<?xml version="1.0" encoding="UTF-8"?>
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<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKS9</accession>
    <name>A0A1J1GKS9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00068100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG92977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525799.1">
        <property type="nucleotide sequence ID" value="XM_028671421.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729206"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00068100"/>
    <dbReference type="OrthoDB" id="370483at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="681"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1100"/>
            <end position="1127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG92977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1850" mass="220845" checksum="17A2B41B0D23A8A3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKW8</accession>
    <name>A0A1J1GKW8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00076200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525878.1">
        <property type="nucleotide sequence ID" value="XM_028670000.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKW8"/>
    <dbReference type="GeneID" id="39729287"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00076200"/>
    <dbReference type="OMA" id="VNTQGIC"/>
    <dbReference type="OrthoDB" id="368411at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012000751" evidence="1">
        <location>
            <begin position="22"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="231" mass="27348" checksum="D7EB75B0FA5AE5AA" modified="2017-02-15" version="1">MISVVKRLVCCVLLCVIVVSSFNFNNEIKQKNYLVLQKAYIDCKNYNVVNNKNKNLSINYGELYCNEDPFCQYFLFNNKKKEIRLCYDKKIVLKKPKYDHLWLTSIKVKVFENFSPCLVNTQGICNHKVDKFFFNTLNEAIKKRKEIKENFMILNFQPKEKEKKIEAYFCETIDYFVDREGYVVFDFIKIKNPHQSCLRTQKCSLRGSIQLDDSKHDKGINPGDIVEAHKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKX7</accession>
    <name>A0A1J1GKX7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">PPM9</name>
        <name evidence="12" type="ORF">PGAL8A_00067500</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG92971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525793.1">
        <property type="nucleotide sequence ID" value="XM_028670754.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKX7"/>
    <dbReference type="GeneID" id="39729200"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00067500"/>
    <dbReference type="OMA" id="NKMFIAN"/>
    <dbReference type="OrthoDB" id="10264738at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF803">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="11">
        <location>
            <begin position="115"/>
            <end position="638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG92971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="639" mass="74852" checksum="12A73C1361D92902" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKY8</accession>
    <name>A0A1J1GKY8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="6">PPIase</shortName>
            <ecNumber evidence="6">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00076000</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525876.1">
        <property type="nucleotide sequence ID" value="XM_028669978.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKY8"/>
    <dbReference type="GeneID" id="39729285"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00076000"/>
    <dbReference type="OMA" id="PYHKANF"/>
    <dbReference type="OrthoDB" id="271386at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000003">
        <property type="entry name" value="Peptidylprolyl isomerase domain and WD repeat-containing 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF4">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE DOMAIN AND WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 6 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6" id="KW-0697">Rotamase</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="8">
        <location>
            <begin position="51"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="5"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="202" mass="22892" checksum="9D76D43779A1A451" modified="2017-02-15" version="1">MFTLCKGYSDDEEEEKNLVDSLEEKKKSLEEKISYYKLKGKDERGKITIYTNLGDFEIELYWYHSPKTCLNFYTLCNMGYYDNTIFHRVIPNYIIQGGDPTGTGKGGKSIYGEYFEDEINCELKHTGAGILSMSNNGPNTNTSQFFITLCPLPHLDGKHTIFARVSKNMTCIESIASVQTTATNKPIFDVKILRTSTAINVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL74</accession>
    <name>A0A1J1GL74_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00078600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525906.1">
        <property type="nucleotide sequence ID" value="XM_028670311.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL74"/>
    <dbReference type="GeneID" id="39729311"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00078600"/>
    <dbReference type="OMA" id="WATHTTH"/>
    <dbReference type="OrthoDB" id="361691at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00043">
        <property type="entry name" value="CYCLIN_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="615"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="650"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="258"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="745"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="907"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="258"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="331"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="350"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="381"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1124" mass="134222" checksum="7E2F66DC8C9DA3B7" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLD1</accession>
    <name>A0A1J1GLD1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="11">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">PGAL8A_00087300</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="11"/>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525991.1">
        <property type="nucleotide sequence ID" value="XM_028671255.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLD1"/>
    <dbReference type="GeneID" id="39729397"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00087300"/>
    <dbReference type="OMA" id="FVPCEHT"/>
    <dbReference type="OrthoDB" id="361536at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016652">
        <property type="entry name" value="Ubiquitinyl_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041432">
        <property type="entry name" value="UBP13_Znf-UBP_var"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001607">
        <property type="entry name" value="Znf_UBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF664">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02148">
        <property type="entry name" value="zf-UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17807">
        <property type="entry name" value="zf-UBP_var"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016308">
        <property type="entry name" value="UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00290">
        <property type="entry name" value="ZnF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50271">
        <property type="entry name" value="ZF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11 19" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 11" id="KW-0645">Protease</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="9 11" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="7 11" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="10 11 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBP-type" evidence="18">
        <location>
            <begin position="164"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="17">
        <location>
            <begin position="321"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="16">
        <location>
            <begin position="667"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="16">
        <location>
            <begin position="726"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="477"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="477"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="12">
        <location>
            <position position="330"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="808"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR016308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR016308-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR016308-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="CRG93169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="847" mass="98411" checksum="7105A02629C4E8CD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLH2</accession>
    <name>A0A1J1GLH2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">RNA-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00096000</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HTATSF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526076.1">
        <property type="nucleotide sequence ID" value="XM_028672200.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLH2"/>
    <dbReference type="GeneID" id="39729484"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00096000"/>
    <dbReference type="OMA" id="EVYFYDG"/>
    <dbReference type="OrthoDB" id="10258585at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12281">
        <property type="entry name" value="RRM1_TatSF1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034393">
        <property type="entry name" value="TatSF1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034392">
        <property type="entry name" value="TatSF1-like_RRM1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15608:SF0">
        <property type="entry name" value="HIV TAT-SPECIFIC FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15608">
        <property type="entry name" value="SPLICING FACTOR U2AF-ASSOCIATED PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="218"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="172"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="501" mass="59080" checksum="7676BC2CA48EEA51" modified="2017-02-15" version="1">MKEVNETKPHHITKDNTDLLNIGKENVLNDKKMSEPNNLTQNKEENNLIHDKKDCNIEKNDTSNEWIIYVNNNSYGPYNFDQIIELWNENRINLMTPIYKKGENNWKYIYNDNILKNYIYNKNKDENNLINSQNNFNLINESNENNSSEYLNSSSSKNFNINNIKDNNNNKNEILNEKITSNTLDLEKLRKKEKKKKYLERKKKKIEEGLCDRKIKNSSIYITGLPKDVTKEEIHNVFKKAGIIKIDAESTEPKIKIYYDENNNIKGDALITYVYSQSVDIAIKYFDNFYFRQDCIIHVEKAQFNKKKQVAKISKEEILKKKKKIKAAKYEQLRLQKWGEYYTGTKKKIVIFRNVFSYEDAMKYDEGDPFYDFIKNLIEAEIKKYVPVHKVYPIPKHPNGIVCVKFKGVEEAEMIVSCFKDIVLNDKKLEVYFYDGKQDLKVQCLTVEKSGRLNTESTSENKGLDKNIDGNNPILMDQSLKSFHEWIDNQSEDEEHEIMVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLI0</accession>
    <name>A0A1J1GLI0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA mismatch repair protein PMS1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PMS1</name>
        <name evidence="7" type="ORF">PGAL8A_00098600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526102.1">
        <property type="nucleotide sequence ID" value="XM_028672488.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLI0"/>
    <dbReference type="GeneID" id="39729510"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00098600"/>
    <dbReference type="OrthoDB" id="10263226at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032389">
        <property type="term" value="C:MutLalpha complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16926">
        <property type="entry name" value="HATPase_MutL-MLH-PMS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000003">
        <property type="entry name" value="DNA mismatch repair endonuclease MutL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.20">
        <property type="entry name" value="MutL, C-terminal domain, dimerisation subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.100">
        <property type="entry name" value="MutL, C-terminal domain, regulatory subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014762">
        <property type="entry name" value="DNA_mismatch_repair_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013507">
        <property type="entry name" value="DNA_mismatch_S5_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002099">
        <property type="entry name" value="MutL/Mlh/PMS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014790">
        <property type="entry name" value="MutL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042120">
        <property type="entry name" value="MutL_C_dimsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042121">
        <property type="entry name" value="MutL_C_regsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037198">
        <property type="entry name" value="MutL_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00585">
        <property type="entry name" value="mutl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073:SF52">
        <property type="entry name" value="MISMATCH REPAIR ENDONUCLEASE PMS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01119">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08676">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01340">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00853">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118116">
        <property type="entry name" value="DNA mismatch repair protein MutL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00058">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair protein S5" evidence="6">
        <location>
            <begin position="219"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="MutL C-terminal dimerisation" evidence="5">
        <location>
            <begin position="953"/>
            <end position="1175"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="627"/>
            <end position="654"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1265" mass="150006" checksum="C3CC6CEEF63BC079" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLN2</accession>
    <name>A0A1J1GLN2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00104200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the proteasome complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase T1B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526158.1">
        <property type="nucleotide sequence ID" value="XM_028673110.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLN2"/>
    <dbReference type="GeneID" id="39729567"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00104200"/>
    <dbReference type="OMA" id="CESLWES"/>
    <dbReference type="OrthoDB" id="204949at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03759">
        <property type="entry name" value="proteasome_beta_type_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000003">
        <property type="entry name" value="Proteasome subunit beta type-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033811">
        <property type="entry name" value="Proteasome_beta_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF10">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA TYPE-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 4 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="218" mass="24505" checksum="B32F49691398E039" modified="2017-02-15" version="1">MGSIFNYNGGCVLGMSGTDCVAIACDLRLGSNGFTTVSTNFTKIFKMNDYVYVGLSGLATDIQTLYELLRFRVNLYQIRQEKLMDVDCFSNMLSSILYSNRFSPYFVNPIVVGFKIKHSIDEKGNKTSTYEPYLTAFDLIGAKCETNDFVINGITSEQLYGMCESLYIKDQDENGLFETISQCILSALDRDCLSGWGAEVYVLTPDKVIKKRLKARMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLS3</accession>
    <name>A0A1J1GLS3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00103500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526151.1">
        <property type="nucleotide sequence ID" value="XM_028673032.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLS3"/>
    <dbReference type="GeneID" id="39729560"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00103500"/>
    <dbReference type="OMA" id="CKGRMME"/>
    <dbReference type="OrthoDB" id="409554at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="151" mass="18521" checksum="7E4DF16905CF9E25" modified="2017-02-15" version="1">MFKRYIWNSIFRDINYRLKKFYHSFYYSQSHIKYVMLILFPAIIWSTRYRTDTKLGYFFYINDEKLYPQYSNNLINTKWKNGTKFYLDDNLTVKDIKKIIYQNEENIPKNIKFGCKGRMMEDTDNLALAVRAFCKRDPKVFIWEDEHAQLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM12</accession>
    <name>A0A1J1GM12_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Kinesin-like protein KIN-8B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00106800</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526185.1">
        <property type="nucleotide sequence ID" value="XM_028673410.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729594"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00106800"/>
    <dbReference type="OMA" id="GAHKISE"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01370">
        <property type="entry name" value="KISc_KIP3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000056">
        <property type="entry name" value="Kinesin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968">
        <property type="entry name" value="CENTROMERE PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968:SF13">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KIF19 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0493">Microtubule</keyword>
    <keyword evidence="5 7" id="KW-0505">Motor protein</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="10">
        <location>
            <begin position="697"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="887"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="1051"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="1180"/>
            <end position="1242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="888"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="790"/>
            <end position="797"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00068376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG93363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1382" mass="160169" checksum="4F7A342EB5556C76" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMB4</accession>
    <name>A0A1J1GMB4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA topoisomerase (ATP-hydrolyzing)</fullName>
            <ecNumber evidence="2">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00124400</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the type II topoisomerase GyrA/ParC subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526359.1">
        <property type="nucleotide sequence ID" value="XM_028674760.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729769"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00124400"/>
    <dbReference type="OrthoDB" id="734at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009330">
        <property type="term" value="C:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.90">
        <property type="entry name" value="DNA gyrase/topoisomerase IV, subunit A, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.199.10">
        <property type="entry name" value="Topoisomerase II, domain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.268.10">
        <property type="entry name" value="Topoisomerase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006691">
        <property type="entry name" value="GyrA/parC_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035516">
        <property type="entry name" value="Gyrase/topoIV_suA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013758">
        <property type="entry name" value="Topo_IIA_A/C_ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013757">
        <property type="entry name" value="Topo_IIA_A_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002205">
        <property type="entry name" value="Topo_IIA_dom_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050220">
        <property type="entry name" value="Type_II_DNA_Topoisomerases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43493:SF5">
        <property type="entry name" value="DNA GYRASE SUBUNIT A, CHLOROPLASTIC_MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43493">
        <property type="entry name" value="DNA GYRASE/TOPOISOMERASE SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03989">
        <property type="entry name" value="DNA_gyraseA_C"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00521">
        <property type="entry name" value="DNA_topoisoIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00434">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101904">
        <property type="entry name" value="GyrA/ParC C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="Type II DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52040">
        <property type="entry name" value="TOPO_IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0799">Topoisomerase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="Topo IIA-type catalytic" evidence="10">
        <location>
            <begin position="187"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1180"/>
            <end position="1237"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="117"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1180"/>
            <end position="1195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1196"/>
            <end position="1218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1219"/>
            <end position="1237"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="6">
        <location>
            <position position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG93537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1314" mass="154157" checksum="AC6D087686C08BCC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMS9</accession>
    <name>A0A1J1GMS9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Mitochondrial import receptor subunit TOM40, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">TOM40</name>
        <name evidence="10" type="ORF">PGAL8A_00145800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tom40 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526574.1">
        <property type="nucleotide sequence ID" value="XM_028674998.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMS9"/>
    <dbReference type="GeneID" id="39729982"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00145800"/>
    <dbReference type="OMA" id="GFMMHIA"/>
    <dbReference type="OrthoDB" id="19656at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07305">
        <property type="entry name" value="Porin3_Tom40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.160.10:FF:000015">
        <property type="entry name" value="Mitochondrial import receptor subunit tom40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="entry name" value="Porin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027246">
        <property type="entry name" value="Porin_Euk/Tom40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037930">
        <property type="entry name" value="Tom40"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10802">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01459">
        <property type="entry name" value="Porin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG93752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="374" mass="43360" checksum="D59928B7F7301CD1" modified="2017-02-15" version="1">MEITNIFKKLLRQNVVYTESNSLFSIFKKQNEETLKEKTEETPNVESLSELKNDSLKKTEEEKLKEQNFLPYTNNFDSSNALLFENLNKEYKFITTQDNFDGFRFEVDKNVNKYLQSTHTLFLGTSLRDIGYLYQFGANFTNSDNSLLMISRINIDGSVNGRFCKKINPNIDCKLNFNTFAKSDTRNMYEMSLEVNKPVYTYNIKTIWQGAWIFNASYTQLLTKKFQAGVDLTYIASNCASIGSFGLRYNHKNNVITMQVIRQPNFKSPEFMLNQTHLYKIQYAKKISDRLSLGTELELTPQTKESAMRLGWDYSFRHAKVQGTIDTSGKISVFTQDYSGFGVSGYIDYLNNEYKFGFMMHISPSQEQPQQQPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNI7</accession>
    <name>A0A1J1GNI7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">26S proteasome regulatory subunit RPN11, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RPN11</name>
        <name evidence="8" type="ORF">PGAL8A_00174600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526860.1">
        <property type="nucleotide sequence ID" value="XM_028670071.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNI7"/>
    <dbReference type="GeneID" id="39730273"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00174600"/>
    <dbReference type="OMA" id="KTGRHEM"/>
    <dbReference type="OrthoDB" id="605656at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08069">
        <property type="entry name" value="MPN_RPN11_CSN5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000026">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050242">
        <property type="entry name" value="JAMM_MPN+_peptidase_M67A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056263">
        <property type="entry name" value="RPN11_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10410">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23594">
        <property type="entry name" value="RPN11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102712">
        <property type="entry name" value="JAB1/MPN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="5 8" id="KW-0647">Proteasome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="7">
        <location>
            <begin position="33"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="311" mass="35188" checksum="A2AAB73B9C8B5BA6" modified="2017-02-15" version="1">MAGIPSSLRELFYSFSDGNGMNNETLADTSEQVYISPLALLKILKHGRAGVPMEVMGLMLGEIVDEYTIRIVDVFAMPQSGNSVSVEAVDPVYQTNMLEELKKTGRHEMVVGWYHSHPGFGCWLSGTDVNTQKSFEQLNPRTIGVVVDPIQSVKGKVVIDCFRLINPHILMLGQEPRQTTSNIGYLTKPTLTALVHGLNRNYYSIVINYRKNELEKNMLLNLHKDIWAKPLKLLDFFEQKKDSDDMLESIKKLTNLYNKSVRNEMKKTNEEILLENIGKIDAKKRIQNSVETLLNDSILTCIGTMANTLFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNJ6</accession>
    <name>A0A1J1GNJ6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Arabinogalactan protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00175400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526868.1">
        <property type="nucleotide sequence ID" value="XM_028670080.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNJ6"/>
    <dbReference type="GeneID" id="39730281"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00175400"/>
    <dbReference type="OMA" id="EFTYLRR"/>
    <dbReference type="OrthoDB" id="1259151at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13214">
        <property type="entry name" value="PH-GRAM_WBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044852">
        <property type="entry name" value="WBP2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31606">
        <property type="entry name" value="WW DOMAIN BINDING PROTEIN 2, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31606:SF1">
        <property type="entry name" value="WW DOMAIN BINDING PROTEIN 2, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="354"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="354"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="373"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="420" mass="49594" checksum="915F9853E64E64F2" modified="2017-02-15" version="1">MALNPTLIQGNEYLFPANKGSEFTYLRRNDVKLKLYLPDRTIKEDGMIFLTSTRLVFVKSEQSKTNSNFAGVELPLNLIEKPKFEQPVFGLNYLSGMIKPLIDHPNSLKSTCKWNITFLNGQCSNFLNYFFKVYEASKKNKPLGTLSEFNEQFFSNSNAYVDPNDPTFLYINEPLPENLYKPQNISQNHYIPINTANNNPVVQQLNNQNEDIPVYKRPYIPRNNNVNNFIPYNQQHYIANCDPTNNGSMYNQQSYLSNNYDHQNNMHNFNQQNTNIPNYDHHNNNLSHYNQQENRMMYNHKDNMPLYNQQNSLMNYDHMNNRNIHNQHNNIHNSEYNLQNNRTHCNQRINQLHNQPNNQQFNPAYNQHFNSSYNQPCNIPPYNQQYNQQLNGQLNQQNDASYNAPYNQPYNQQQNQSYNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNV9</accession>
    <name>A0A1J1GNV9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Inner membrane complex sub-compartment protein 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ISP1</name>
        <name evidence="2" type="ORF">PGAL8A_00387300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526990.1">
        <property type="nucleotide sequence ID" value="XM_028670216.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNV9"/>
    <dbReference type="GeneID" id="39732403"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00387300"/>
    <dbReference type="OMA" id="FIFIMRD"/>
    <dbReference type="OrthoDB" id="328439at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000358">
        <property type="entry name" value="Inner membrane complex sub-compartment protein 1 (ISP1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041316">
        <property type="entry name" value="ISP1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18161">
        <property type="entry name" value="ISP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ISP1 C-terminal" evidence="1">
        <location>
            <begin position="34"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="144" mass="16576" checksum="A02C623E9F2635CA" modified="2017-02-15" version="1">MGNIVSCCSLDDNKKNINEDEILEKFSNNEINEFKKRLKNNIQIVVLLQDGTKLPCNLQANFHEKTLCISCQQKVRMINFSDIRSLLYGEEQLKRVETQANLINDNCCLALHLDDSGNCIPIKFGSVKEKNLFIFVMKDYKKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNW5</accession>
    <name>A0A1J1GNW5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Heme oxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">HO</name>
        <name evidence="1" type="ORF">PGAL8A_00388100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526998.1">
        <property type="nucleotide sequence ID" value="XM_028670225.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNW5"/>
    <dbReference type="GeneID" id="39732411"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00388100"/>
    <dbReference type="OrthoDB" id="365431at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.910.10">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016084">
        <property type="entry name" value="Haem_Oase-like_multi-hlx"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48613">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="300" mass="36421" checksum="B532725774DFF3BF" modified="2017-02-15" version="1">MIKIILLSFLIIIFFSNVFNKKLYNIYKKNTKNNLTFINVLKCKQKYQLNAKKFINFKEIQLQRITEYRKRSGSNKNNINYNSRDKYNYHENLNEVLPTLAKIENEKLKEKEKYREIFRNINDYNILFTRQTFLQFLIDLYNIFLKIDEAFIIYKKDFSPLIYIGPMQLTNYLYNDIIYLSSIVDNPDDITVSQYGREYISYLEELCEKNKLKFLAQSYVFYKNFHLTKEHLLNSICKYLNIFKKLKSSTYVSDVSNFEYCLNKISRKWSRWEKDHFLSGLYDATDKMMILTKHFQQTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP98</accession>
    <name>A0A1J1GP98_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UDP-N-acetylglucosamine transferase subunit ALG14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00402300</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ALG14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527140.1">
        <property type="nucleotide sequence ID" value="XM_028670382.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP98"/>
    <dbReference type="GeneID" id="39732553"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00402300"/>
    <dbReference type="OMA" id="GTCCIIT"/>
    <dbReference type="OrthoDB" id="5978656at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043541">
        <property type="term" value="C:UDP-N-acetylglucosamine transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004577">
        <property type="term" value="F:N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013969">
        <property type="entry name" value="Oligosacch_biosynth_Alg14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12154">
        <property type="entry name" value="GLYCOSYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12154:SF4">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE TRANSFERASE SUBUNIT ALG14 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08660">
        <property type="entry name" value="Alg14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="205" mass="24622" checksum="DEDC1A8EA8D0F143" modified="2017-02-15" version="1">MFSMFIYINIFFFLWFFLILKNKFYEDKNDKKKEIEIGVVLGSGGHTFEIIEILKILKNNDNIFNFFYASNDIFSKIKVEKILKNYKKKFLIIPRCRNVGESYILSFIKFFFTFIYCIFLTYKMNNMKLIIVNGPGTCLPVVFSLLFRKYIFFKTIKIVYIESVCRIYSLSLTAKLLYVFADLFVVFSEHLEKKYKKAKFYGYLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPG3</accession>
    <name>A0A1J1GPG3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00390000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527017.1">
        <property type="nucleotide sequence ID" value="XM_028670246.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPG3"/>
    <dbReference type="GeneID" id="39732430"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00390000"/>
    <dbReference type="OMA" id="ELITFYT"/>
    <dbReference type="OrthoDB" id="387578at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="362"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="384" mass="45592" checksum="A076E13464CD0280" modified="2017-02-15" version="1">MLYYIIEQKKIRILCLVILYYFSFLITIQANANNYMLKIHEPLKKLKRGSTYKYDKRDVKNIMDFSFVSKNEVKEKDPHVEKEKKEDDKSLTLENEKKNKEKKNKDKKKEKKINLDEMEEHISEDEEEERDEEIDTIKKKGKEKDNRKDEEKNENKKKAKGDDEDEDEDEDEEEGEGEDEYDDEDDGEKKKKNENEKKNKDKKKGNESSEEHHEENNEKDKKKEKKEGEKNNPEGKENTENLKHDEQKSDIYPIITNGAQNMTPTLENNMQTKEEKITPEKDTKTNEDLHIPEDIKKNFMKLLRSVVEVNKNDLDKKENTHFREGEDKNHGVSPLHDKYNNGNELHNSLSLLNKIIEHFKKYMIYYAIGFIVFSVFALSLQCSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPS7</accession>
    <name>A0A1J1GPS7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00100100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526117.1">
        <property type="nucleotide sequence ID" value="XM_028672655.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPS7"/>
    <dbReference type="GeneID" id="39729525"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00100100"/>
    <dbReference type="OrthoDB" id="10361567at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="456" mass="55016" checksum="8448FB46BA62444C" modified="2017-02-15" version="1">MVPLLKTNELIYKTLNYTLDIFEISNEKKMLNIFHKINELIYLRGEKSVLNDGNKIHFAKYSDLIKEMEIYCEMNKKCLYLYENKEITYKLIKCFEKCFNNTFIDNSKIYPIFKLNIKDFLNLHIHKHISSQEFQFFLFLYLEKFLYSFSLFSYKYSIKNLSEGVILYNFENVNTVDLNNAFFYLLMRDINCIISIIIPIYINTILIYKSRNLKEKIYKIYNLIENKSCKTIFIEEEDDLLDVIKLENTYAHHITTKNKEKNTLCDYNNFFLLNIILDENHNDTENFVEHFDLSEMLIKAHINFMKIHKKLKRKIEIQNNYIQKKNSKLNLCKNNLETKNGKEKLDDKEKMNFLEKNVFSNIFDFKYFIDAANKYHEDALIKNETEKKIIDFITQSNLHNRKIINKKIQDVSIGDMYIYYRKNESKKEIKKEKAFIDLEKVFRKNVTTCIFRDNLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPS9</accession>
    <name>A0A1J1GPS9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cell cycle control protein cwf15, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00184200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CWC15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527271.1">
        <property type="nucleotide sequence ID" value="XM_028670527.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPS9"/>
    <dbReference type="GeneID" id="39730369"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00184200"/>
    <dbReference type="OMA" id="FRNTCER"/>
    <dbReference type="OrthoDB" id="30179at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006973">
        <property type="entry name" value="Cwf_Cwc_15"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12718">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN CWF15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12718:SF2">
        <property type="entry name" value="SPLICEOSOME-ASSOCIATED PROTEIN CWC15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04889">
        <property type="entry name" value="Cwf_Cwc_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="118"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="138"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="188"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="272" mass="32530" checksum="C39C54B62DE05250" modified="2017-02-15" version="1">MTTAHRPTWYNAIGGENQGGNRKVSQTVKVCSRDLPSHTKMKTRDLSDYVEDKTLIKNNLLKLENNNNNDTKTNKLLAIENIKKYTNQEYTNPFPQDEDDEIDDDFKSYKKKDKKKKKKNFKINISNNNDTNKKDTDNEKDEEYEDENDEYEDEYEDDDDDDDDDDDDDDDEEKELLRELENLKREKLEKLKKEKEEQEIMKNKKNNVLTNNPLINLEDSDNENSEKNVKKRKWTEEAIFRNTCERKEKKVSFINDTVRSAFHKKFLFKYIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPX8</accession>
    <name>A0A1J1GPX8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Photosensitized INA-labeled protein 1, PhIL1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00104900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526165.1">
        <property type="nucleotide sequence ID" value="XM_028673187.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPX8"/>
    <dbReference type="GeneID" id="39729574"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00104900"/>
    <dbReference type="OMA" id="NSEWCNA"/>
    <dbReference type="OrthoDB" id="360786at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="222" mass="25561" checksum="0A065251F4628087" modified="2017-02-15" version="1">MLSSILPKRYYFDKQGKIKEIDLLSCKTIISPQKHVDTKDNLTCTTHVLPNIYETTHNFPKMNLTHENNFDNVEMNTNVYVNQEPSMNNVNAVPYAADQYNNIQEVNIHEITQPLTFADGNLYYADGPQGIDPGVLAVSNALFAYNSSFQSIPIKTSPKVFRRRRRGETNSEWSNAFVTRVDPCECTEPEEEYKPYEVTKYYDESGVKTVFNFDHEPFHEAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ14</accession>
    <name>A0A1J1GQ14_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Small nuclear ribonucleoprotein Sm D2</fullName>
            <shortName evidence="10">Sm-D2</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">snRNP core protein D2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00409200</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the snRNP core protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527209.1">
        <property type="nucleotide sequence ID" value="XM_028670459.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ14"/>
    <dbReference type="GeneID" id="39732622"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00409200"/>
    <dbReference type="OMA" id="DVKEMWT"/>
    <dbReference type="OrthoDB" id="437526at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030532">
        <property type="term" value="C:small nuclear ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005689">
        <property type="term" value="C:U12-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01720">
        <property type="entry name" value="Sm_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000069">
        <property type="entry name" value="Small nuclear ribonucleoprotein Sm D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027248">
        <property type="entry name" value="Sm_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12777">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN SM D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 10" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7 10" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 10 12" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="11">
        <location>
            <begin position="19"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG94388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="101" mass="11817" checksum="351466ACB1B2D66A" modified="2017-02-15" version="1">MKSETQVEENRDNPEDGPLGLLSECVKDNSQVLVNCRNNRKLLGRVKAFDRHCNLLLTEVREIWVEIVKDKKKKKKINKDRYISILFLRGDSVILILRNPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ42</accession>
    <name>A0A1J1GQ42_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00194400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000030">
        <property type="protein sequence ID" value="CRG94547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527362.1">
        <property type="nucleotide sequence ID" value="XM_028670628.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ42"/>
    <dbReference type="GeneID" id="39730470"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00194400"/>
    <dbReference type="OMA" id="NDISCIQ"/>
    <dbReference type="OrthoDB" id="10591120at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012249866" evidence="3">
        <location>
            <begin position="23"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="447"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="86"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="447"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="965" mass="112443" checksum="35EB687554F95738" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQA1</accession>
    <name>A0A1J1GQA1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00201600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527434.1">
        <property type="nucleotide sequence ID" value="XM_028670708.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730542"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00201600"/>
    <dbReference type="OMA" id="MISNHYN"/>
    <dbReference type="OrthoDB" id="378574at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="518"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="588"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="630"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="782"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="878"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1041"/>
            <end position="1092"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1541"/>
            <end position="1575"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1883"/>
            <end position="1943"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="540"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="589"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="782"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="795"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="878"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="902"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1055"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1081"/>
            <end position="1091"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2195" mass="259302" checksum="1CD174F76517FB71" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQC4</accession>
    <name>A0A1J1GQC4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">tRNA pseudouridine synthase D, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00094800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pseudouridine synthase TruD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526064.1">
        <property type="nucleotide sequence ID" value="XM_028672065.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQC4"/>
    <dbReference type="GeneID" id="39729472"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00094800"/>
    <dbReference type="OrthoDB" id="447290at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.20">
        <property type="entry name" value="TruD, catalytic domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001656">
        <property type="entry name" value="PsdUridine_synth_TruD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011760">
        <property type="entry name" value="PsdUridine_synth_TruD_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042214">
        <property type="entry name" value="TruD_catalytic"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13326:SF21">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE PUS7L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13326">
        <property type="entry name" value="TRNA PSEUDOURIDINE SYNTHASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01142">
        <property type="entry name" value="TruD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037016">
        <property type="entry name" value="Pseudouridin_synth_euk_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50984">
        <property type="entry name" value="TRUD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TRUD" evidence="3">
        <location>
            <begin position="303"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="854" mass="102727" checksum="60A047CC5EC029F1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQI7</accession>
    <name>A0A1J1GQI7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00194900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527369.1">
        <property type="nucleotide sequence ID" value="XM_028670636.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQI7"/>
    <dbReference type="GeneID" id="39730476"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00194900"/>
    <dbReference type="OMA" id="WVDYFND"/>
    <dbReference type="OrthoDB" id="386257at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="257" mass="30887" checksum="92B5DA41F7DCF797" modified="2017-02-15" version="1">MKFSTALYFFYYFLVINWLTPCISIRSEPPLYFPLGVDELKHLLRHSLMTGVTNSAKIINFKFNVMEASVEKFKNSTQEERNEMLNSKDQLLNAITKLAELKDLKIEEVVLKYIANFVMDELIRINEGNLNEAQGYQECREYSGNYDIYIDQKCKMILKEMKYIWNSNIFIKDIDPLWKDEKWDLWYKNYTHFVTALKKNNYMIFLSMLQKNIQKKSCKGIYEFLEKDFMRSYYGPLMAEFDKFFKETLGEWRKKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQK3</accession>
    <name>A0A1J1GQK3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00221800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527636.1">
        <property type="nucleotide sequence ID" value="XM_028670933.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730745"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00221800"/>
    <dbReference type="OMA" id="NDMNNDM"/>
    <dbReference type="OrthoDB" id="385893at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1314"/>
            <end position="1364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1538"/>
            <end position="1562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2403"/>
            <end position="2480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2512"/>
            <end position="2538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2559"/>
            <end position="2589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1323"/>
            <end position="1358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="2412"/>
            <end position="2449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2450"/>
            <end position="2460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2468"/>
            <end position="2480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2518"/>
            <end position="2528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2566"/>
            <end position="2576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2982" mass="353829" checksum="5D3B1B85FDAF3D65" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQP8</accession>
    <name>A0A1J1GQP8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Zinc finger protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00223600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527654.1">
        <property type="nucleotide sequence ID" value="XM_028670952.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQP8"/>
    <dbReference type="GeneID" id="39730763"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00223600"/>
    <dbReference type="OMA" id="FFCRNNV"/>
    <dbReference type="OrthoDB" id="411372at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045124">
        <property type="entry name" value="Su(sable)-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13119:SF12">
        <property type="entry name" value="PROTEIN SUPPRESSOR OF SABLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13119">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="67"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="98"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="67"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="98"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="282"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="26"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="285"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="340" mass="40743" checksum="BB4DA5303BE9C157" modified="2017-02-15" version="1">MEKINDKQILEKISTITGGLTNTSVIKKKSKKKKKKRKNAKLDEKKKSITKNRKRKIVDLFEDYKLQQKKETCKFFFKKGKCIHNENCSYSHDVIPIYKISKLCKFLVKGTCDKKNCIFSHDYQLFYCRNNVIFNSCNNPFCKFKHIKIGNTINNADEYNLEVDNVLSKDDKIRFLYNNKNYLMELLIHKYHNFDNYEEINVDELIKKDNYPWFINGIIDLIKLDFKYNKADVFFKLVKNYMNKTNNLKCYIDKDNLKILQNDKNHNELSKKNTILENINSENNNESKEELNTFEKNNKDNKTNTNDTNNTTENFNDYKFYSSEEEDYTQYLNKYFEIDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQU6</accession>
    <name>A0A1J1GQU6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mitochondrial ribosomal protein S6-2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00223200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527650.1">
        <property type="nucleotide sequence ID" value="XM_028670948.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQU6"/>
    <dbReference type="GeneID" id="39730759"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00223200"/>
    <dbReference type="OMA" id="FFHSNTF"/>
    <dbReference type="OrthoDB" id="363348at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070181">
        <property type="term" value="F:small ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15465">
        <property type="entry name" value="bS6_mito"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00360">
        <property type="entry name" value="Ribosomal_bS6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000529">
        <property type="entry name" value="Ribosomal_bS6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035980">
        <property type="entry name" value="Ribosomal_bS6_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020814">
        <property type="entry name" value="Ribosomal_S6_plastid/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribsomal_bS6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21011">
        <property type="entry name" value="MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21011:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN BS6M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01250">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54995">
        <property type="entry name" value="Ribosomal protein S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="114" mass="13720" checksum="E63714C9E3A87359" modified="2017-02-15" version="1">MVLYESYIALNKHIKKEDVKNLMKNFNFIINKYNGNIININDLGWRKFAFCIKKPKVGTFHFARFYCITFYSNSKSIKDLNEFFHSNTFILRFLNVKMKYRSNFLVAPFTHINE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRH5</accession>
    <name>A0A1J1GRH5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide repeat protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00159600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526709.1">
        <property type="nucleotide sequence ID" value="XM_028675149.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRH5"/>
    <dbReference type="GeneID" id="39730121"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00159600"/>
    <dbReference type="OMA" id="ADLCCIH"/>
    <dbReference type="OrthoDB" id="420945at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045842">
        <property type="term" value="P:positive regulation of mitotic metaphase/anaphase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558">
        <property type="entry name" value="CELL DIVISION CYCLE 16,23,27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558:SF45">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_12, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="161"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="228"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="278" mass="32635" checksum="B11885E6AFC8E402" modified="2017-02-15" version="1">MGGSASKNLEYYNYTSMRLLDTENYENEEEYFKEHDVEEIIRKAREIRSYNFKESLDLYFKCLKILKKLKDDNSRIYKNVLEFEIKPLDMANKSLKLDPQNLGQKNKRYDSSSSITVDNVSINKKIASLYNEIGDLCCMHDFIDKSLFYYDKACSYNPSKVDYIYKKGVLYQQMNETEKAINTFKRILSTDENHIPTLFSLGNLYRYIDSNIALAYFEAILKKEPNNTEVLSLIASCYDNLGNLNEAISYQNKVVQINPDNFNHKKFAQRLIEMKLQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRV9</accession>
    <name>A0A1J1GRV9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00243400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527849.1">
        <property type="nucleotide sequence ID" value="XM_028671170.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRV9"/>
    <dbReference type="GeneID" id="39730962"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00243400"/>
    <dbReference type="OMA" id="MPIHCIL"/>
    <dbReference type="OrthoDB" id="385061at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="188"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="21"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="374" mass="44634" checksum="18E7D1761D3ABBEE" modified="2017-02-15" version="1">MEENCEVNTKSSFFDDDISIESKKEKEYEIKNNKNEQIKEEMKSIEVNLNNEMESTIIMNYKKRKTTNLDEIYYSLKLPKFIDVNSEIIKKKKSYIECEQEEGEIESLNKNKSSIISWSFDEEMYNKKKIENNKTDKENEDKLFFGDDINIKNDNNEEYIDKINVNEKKIFVNNELEYSCKKEDENKLFNENDEKDPNKSDEVKDKEENLNSFSTKSNKLDKIKKEYSTDEESNFNENMSDLTNLEDLYEKYEIENSDIMSISSNESNENMKDLCNNLKYLETNSFIVEYEDGKFIFFVNQKPYILEEDNEVNYLIESTDQNIKPIHCKLEKKFFVKSFTTEEQIIPSSLKLKKEDIYYSLDDNMKINEEIEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRW1</accession>
    <name>A0A1J1GRW1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00261000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528018.1">
        <property type="nucleotide sequence ID" value="XM_028671358.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRW1"/>
    <dbReference type="GeneID" id="39731139"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00261000"/>
    <dbReference type="OMA" id="AIGEHTD"/>
    <dbReference type="OrthoDB" id="372098at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="17"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="267" mass="32304" checksum="14E2C6FE3B7D649C" modified="2017-02-15" version="1">MQKNTYNFDVGYFLKSCTDLEQSYEVLLNEKKKSELKLNEVSKNLQEIKEKYEKEKKNNLEISFNISEQTDKLIKKQNYFENYENVKKQNEDFKRKIEILKKEKQFEKQNMMEKIKIAERKKHQEIEEYEKKMRQNKNMLLELESQIKELDFEISSKNIEIKRLSSIINDIQQKHEKKKLEYEQKIKDLIKENEEINRKNKEVINNLINESNNPSLDNLKNKLKLQQQEPIKLEGEHLNLKKSINKTSNKKSVSTMHTRNNKILYKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS30</accession>
    <name>A0A1J1GS30_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00381600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526933.1">
        <property type="nucleotide sequence ID" value="XM_028670152.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS30"/>
    <dbReference type="GeneID" id="39732346"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00381600"/>
    <dbReference type="OrthoDB" id="375435at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="290" mass="35452" checksum="CDC3CAD30E8B9654" modified="2017-02-15" version="1">MIKINPELKKRFLTFEEAKMLVISTLKRGRAIEILNKIINEKYILRKFFCHLKIQNKLRLIKKEYFPISICKIEKTIKCKLSKIFSELRNYSKNSTYFISNCKNFKDFKKIYGVFKLEKALKSYTHKLLFTFISKCLILRDINFSKTDKNEIREIINNFKSFKKNDIFLYNFNYNIRKSNTYYKYINDKLPKKTSNNNINFNHKVFDFLLHNNIKTKKKEKKYSLENFYDEYPLKPYYYEELPSIKLSHNFDLFIKDSYQNDNENILPYIKYLLYIKDEYNNYGFFEEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS68</accession>
    <name>A0A1J1GS68_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">RNA polymerase II transcription factor B subunit 4, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">TFB4</name>
        <name evidence="12" type="ORF">PGAL8A_00159900</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the TFB4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526712.1">
        <property type="nucleotide sequence ID" value="XM_028675152.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS68"/>
    <dbReference type="GeneID" id="39730124"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00159900"/>
    <dbReference type="OMA" id="IAVCSCH"/>
    <dbReference type="OrthoDB" id="17307at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000439">
        <property type="term" value="C:transcription factor TFIIH core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004600">
        <property type="entry name" value="TFIIH_Tfb4/GTF2H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12831:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12831">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIH TFIIH , POLYPEPTIDE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03850">
        <property type="entry name" value="Tfb4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9 11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 11" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6 11" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG93891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="323" mass="37662" checksum="FC9921303D99E5F9" modified="2017-02-15" version="1">MQKNEEVCSKTGNLKDEKEVVKNHLIIVVDVNILIWCEGLKIKFDKNQVKNLKLSDFFKSLFQFIRFYCFMSNSERLCLIATSSNNCKIIYENYISYTKNNLAENDYCSDTYDNLINFINENKNSKLSESTLSSALIIALCYNNKICNLYENINTRIFLLDISKSHFYTNQYTQLMNIAYNAKRNNVIIDVLSLNHKTKILEQICNITNGLYIDNSIFLNVNCNDKIEDILTQTMIFWFLPSNNSRKYFSNTYLNEDTNIAVCSCHNKQIDIAYICSCCLTIYCSEKDFQTNKDRICCSICKTRFTKSLLRNKIVSDLDFTII</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS72</accession>
    <name>A0A1J1GS72_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">40S ribosomal protein S6, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00253100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527939.1">
        <property type="nucleotide sequence ID" value="XM_028671270.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS72"/>
    <dbReference type="GeneID" id="39731059"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00253100"/>
    <dbReference type="OMA" id="KPRYKAP"/>
    <dbReference type="OrthoDB" id="10260596at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001377">
        <property type="entry name" value="Ribosomal_eS6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018282">
        <property type="entry name" value="Ribosomal_eS6_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11502">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01092">
        <property type="entry name" value="Ribosomal_S6e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01405">
        <property type="entry name" value="Ribosomal_S6e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00578">
        <property type="entry name" value="RIBOSOMAL_S6E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="219"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="229"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="243"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="315" mass="36418" checksum="5ED4EEA2ADA477A6" modified="2017-02-15" version="1">MKLNISNPLNNVQKSIEIDDEKKLLPFMEKRIGNVVPGDSIGEEFTGYVFRITGGNDKQGFPMMQGVLTNNRVRLLFKKGMKCYRPRKKGERKRKSVRGCIVGQDLSALNLTLVKKGTNEIPGLTDKTVGKKLGPKRASKIRKLFNLDKTDDVRKYVIGRSVTKNGKTRIIKPKIQRLVTEKRLFRKRKLMEAKKKRKLEKCKALKEYKHVLKMYRKKMASKKEEETGKKKKVKKTISKKNVKKDEKNRDKNANIKNKVKTENVEKTAIKKDKKTEKPKGDKQIKSENKTKIEKKTVAKDHKEGNKGDKKKKNQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS75</accession>
    <name>A0A1J1GS75_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Putative rRNA methyltransferase</fullName>
            <ecNumber evidence="8">2.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">2'-O-ribose RNA methyltransferase SPB1 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00160700</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a ribonucleotide in rRNA + S-adenosyl-L-methionine = a 2'-O-methylribonucleotide in rRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48628"/>
            <dbReference type="Rhea" id="RHEA-COMP:12164"/>
            <dbReference type="Rhea" id="RHEA-COMP:12165"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90675"/>
            <dbReference type="ChEBI" id="CHEBI:90676"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
            <location evidence="1 8">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526720.1">
        <property type="nucleotide sequence ID" value="XM_028675161.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS75"/>
    <dbReference type="GeneID" id="39730132"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00160700"/>
    <dbReference type="OMA" id="MAGGDSH"/>
    <dbReference type="OrthoDB" id="1287559at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016435">
        <property type="term" value="F:rRNA (guanine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008650">
        <property type="term" value="F:rRNA (uridine-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000466">
        <property type="term" value="P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000004">
        <property type="entry name" value="AdoMet-dependent rRNA methyltransferase SPB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01547">
        <property type="entry name" value="RNA_methyltr_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03163">
        <property type="entry name" value="RNA_methyltr_E_SPB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050082">
        <property type="entry name" value="RNA_methyltr_RlmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002877">
        <property type="entry name" value="RNA_MeTrfase_FtsJ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015507">
        <property type="entry name" value="rRNA-MeTfrase_E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012920">
        <property type="entry name" value="rRNA_MeTfrase_SPB1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024576">
        <property type="entry name" value="rRNA_MeTfrase_Spb1_DUF3381"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028589">
        <property type="entry name" value="SPB1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10920:SF13">
        <property type="entry name" value="PRE-RRNA 2'-O-RIBOSE RNA METHYLTRANSFERASE FTSJ3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10920">
        <property type="entry name" value="RIBOSOMAL RNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11861">
        <property type="entry name" value="DUF3381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01728">
        <property type="entry name" value="FtsJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07780">
        <property type="entry name" value="Spb1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 8 13" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3 8" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6 8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 8 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribosomal RNA methyltransferase FtsJ" evidence="10">
        <location>
            <begin position="24"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3381" evidence="12">
        <location>
            <begin position="263"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal RNA methyltransferase SPB1-like C-terminal" evidence="11">
        <location>
            <begin position="788"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="371"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="935"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="532"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="869"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="371"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="958"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="158"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF11861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG93899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="991" mass="117609" checksum="FD708AF30885DDFA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS89</accession>
    <name>A0A1J1GS89_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">PRE-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PREBP</name>
        <name evidence="6" type="ORF">PGAL8A_00388000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526997.1">
        <property type="nucleotide sequence ID" value="XM_028670224.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS89"/>
    <dbReference type="GeneID" id="39732410"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00388000"/>
    <dbReference type="OMA" id="CAYELND"/>
    <dbReference type="OrthoDB" id="427410at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00105">
        <property type="entry name" value="KH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056247">
        <property type="entry name" value="KH_DEAH11/12_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24641">
        <property type="entry name" value="KH_DEAH11_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="686"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="5">
        <location>
            <begin position="764"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="32"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="836"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="292"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="666"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="32"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="49"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="64"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="98"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="129"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="851"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="861"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="909"/>
            <end position="921"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG94176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="921" mass="106926" checksum="C839F281C1C09F16" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSA2</accession>
    <name>A0A1J1GSA2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA polymerase epsilon subunit b, putative</fullName>
            <ecNumber evidence="5">2.7.7.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00007400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA polymerase delta/II small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528119.1">
        <property type="nucleotide sequence ID" value="XM_028671470.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSA2"/>
    <dbReference type="GeneID" id="39728596"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00007400"/>
    <dbReference type="OMA" id="HCILIGT"/>
    <dbReference type="OrthoDB" id="3763at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043625">
        <property type="term" value="C:delta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007185">
        <property type="entry name" value="DNA_pol_a/d/e_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040663">
        <property type="entry name" value="DNA_pol_D_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024826">
        <property type="entry name" value="DNA_pol_delta/II_ssu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10416">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10416:SF0">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18018">
        <property type="entry name" value="DNA_pol_D_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04042">
        <property type="entry name" value="DNA_pol_E_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA polymerase delta subunit OB-fold" evidence="4">
        <location>
            <begin position="52"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="DNA polymerase alpha/delta/epsilon subunit B" evidence="3">
        <location>
            <begin position="205"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF18018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="449" mass="51832" checksum="C0D5835C6F687516" modified="2017-02-15" version="1">MDAQITNKDVEDIINHINENELHLNKKIKRKHFNYENLSKEFLLIDPTYTQQYSEIYCLRIKIMKNLLMKTIEMLKDDKKKDNDEYNVLNYLKEIKANEKCYCIGTLFKKMQLRPSILKEYLSEINIVETLVNFSHEEDTLFLEDETARLRLEGNINSDHYVTGLTLIVKGQGMSNGSLYVEELIYSYLPKLEIPKCISNDDKYILFVSGLYINELNKNINNISLLRNFILGLHGDINISENLIRLIIVGNSLSNLDNDETNLNTIDVFISSICSAVYVDIMPGEKDPSDSNLPQQPFPNLFFRKSKNYNSFQCVTNPYIFSIDNINICCMSGESVNNISSYSKNSKIQSLKIIAQSRILSPTSPDTLGCYPFTKNDPFCIHDDNTYPHIFINGNCSKLEIEYMRNDNNEKQLPLLVCLPSFQITPKALLINTKNMDYKVLTFEVEKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSB5</accession>
    <name>A0A1J1GSB5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">60S ribosomal protein L26, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00012000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528162.1">
        <property type="nucleotide sequence ID" value="XM_028671517.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSB5"/>
    <dbReference type="GeneID" id="39728642"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00012000"/>
    <dbReference type="OMA" id="VRIMRGD"/>
    <dbReference type="OrthoDB" id="1688503at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06089">
        <property type="entry name" value="KOW_RPL26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000009">
        <property type="entry name" value="60S ribosomal protein L26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01326_A">
        <property type="entry name" value="Ribosomal_uL24_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005756">
        <property type="entry name" value="Ribosomal_uL24_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041988">
        <property type="entry name" value="Ribosomal_uL24_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01080">
        <property type="entry name" value="rplX_A_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11143">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L26 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16906">
        <property type="entry name" value="Ribosomal_L26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="KOW" evidence="5">
        <location>
            <begin position="48"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="127" mass="15047" checksum="9501039101C67628" modified="2017-02-15" version="1">MKLNKQKSSSRRKMRKTHFTAPAGLRRKIMSSKLSKELRLKYKTRSLPVRKDDEVLICRGHNHGREGKVVKINRKRYKIYIERVTREKVNGESTFIGIHPSNVILTKLKIDKNRKKILDRKIPKEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSE2</accession>
    <name>A0A1J1GSE2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 9">Adenylosuccinate lyase</fullName>
            <shortName evidence="9">ASL</shortName>
            <ecNumber evidence="4 9">4.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Adenylosuccinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ASL</name>
        <name evidence="12" type="ORF">PGAL8A_00017800</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + fumarate</text>
            <dbReference type="Rhea" id="RHEA:23920"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:58443"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N(6)-(1,2-dicarboxyethyl)-AMP = fumarate + AMP</text>
            <dbReference type="Rhea" id="RHEA:16853"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.2" evidence="4 9"/>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528220.1">
        <property type="nucleotide sequence ID" value="XM_028671582.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSE2"/>
    <dbReference type="GeneID" id="39728700"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00017800"/>
    <dbReference type="OMA" id="NNWAVVA"/>
    <dbReference type="OrthoDB" id="406045at2759"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00132"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00336"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070626">
        <property type="term" value="F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004018">
        <property type="term" value="F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.40.30">
        <property type="entry name" value="Fumarase/aspartase (C-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.200.10">
        <property type="entry name" value="Fumarase/aspartase (Central domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="entry name" value="Fumarase/aspartase (N-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004769">
        <property type="entry name" value="Pur_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047136">
        <property type="entry name" value="PurB_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013539">
        <property type="entry name" value="PurB_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006764">
        <property type="entry name" value="PRK09285.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00928">
        <property type="entry name" value="purB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43411">
        <property type="entry name" value="ADENYLOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43411:SF1">
        <property type="entry name" value="ADENYLOSUCCINATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08328">
        <property type="entry name" value="ASL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="L-aspartase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 9" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumarate lyase N-terminal" evidence="10">
        <location>
            <begin position="15"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="Adenylosuccinate lyase PurB C-terminal" evidence="11">
        <location>
            <begin position="332"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG95409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="470" mass="54593" checksum="9B1C96C5A88EF5DF" modified="2017-02-15" version="1">MESLIKIKNISPIDGRYKKLCEEISSYFSEYALIKYRIIVEIKWLLFLNEKEFFFKKLSESALKSLNEISNVMDDDILRVKKIEEETNHDVKAVEYFIKEKIKLSENQELLNIKEYVHYLCTSEDINNITYGICIKLCLNDIIIPNIKKILDKLNQLAVDYADISLLSKTHGQPASSTTFGKEMANFFSRIYNHLNVLKKIKIYGKFNGAVGNFNSHKIADKNVDWISNIKYFIENYFNLNFGLYCTQIQDHDYICELCDALARINSTLIDLCVDMWLYISNNLLKLKIVQKEIGSSTMPHKVNPIDFENAEGNLHLANSLFKLFSTKLPISRLQRDLSDSTILRNIGSSFSYTLIAYKSLLKGLSKIDIEEKALNKELNENWSTLSEPIQIIMKKYNFPDAYEELKNFTRGKHVNKETMHEFIKTKCNFLPKNVTDELINLTPHSYIGYANYLAQNVKELTEKMQNTNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSG0</accession>
    <name>A0A1J1GSG0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Vesicle transport v-SNARE protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00013300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528175.1">
        <property type="nucleotide sequence ID" value="XM_028671531.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSG0"/>
    <dbReference type="GeneID" id="39728655"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00013300"/>
    <dbReference type="OMA" id="SIYHNKV"/>
    <dbReference type="OrthoDB" id="430637at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="195" mass="23430" checksum="643E30FB7E848E46" modified="2017-02-15" version="1">MITYSEYLDVYVRDFNIYMQKIKNSIFYIKNQEDYKNTKEYILEAEKCIKQIIIEINSLPKGSHKIFEDINKYNLELKKYKNILEKMSDSDENSDNKQLEITRKYIEGSKFLLDSEKRAQDVEDIGYTIMSELNSQRNSILRTKHYTDVNRQEQNRVKRMLINIYKNRLLYKFLLILTIILLVIANIGVIIYKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSQ1</accession>
    <name>A0A1J1GSQ1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00271600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000041">
        <property type="protein sequence ID" value="CRG95515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528324.1">
        <property type="nucleotide sequence ID" value="XM_028671697.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSQ1"/>
    <dbReference type="GeneID" id="39731247"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00271600"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022139">
        <property type="entry name" value="Fam-L/Fam-M-like_plasmodium"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12420">
        <property type="entry name" value="DUF3671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="138" mass="16521" checksum="AE49365CE4E57630" modified="2017-02-15" version="1">MKTFTLYFKIFTFLLLIWIFHCLYNYDSNKSLINRDTSETKIGLKHERMLAEGDKSKKKSSYIKKSVDYYPSGEVDMIIREFIHLMDMYFKCYNANIKTNIVDNVLLNEENEVRYICRNKILNAYRNNISKEKSLSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GST1</accession>
    <name>A0A1J1GST1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00270300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000040">
        <property type="protein sequence ID" value="CRG95502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528311.1">
        <property type="nucleotide sequence ID" value="XM_028671683.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731234"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00270300"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="567"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="293"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="367"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="608"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1338"/>
            <end position="1394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="300"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="378"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="608"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="622"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="654"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="689"/>
            <end position="702"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1532" mass="181736" checksum="68CF005014F1CA2D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSW3</accession>
    <name>A0A1J1GSW3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00014300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528185.1">
        <property type="nucleotide sequence ID" value="XM_028671543.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSW3"/>
    <dbReference type="GeneID" id="39728665"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00014300"/>
    <dbReference type="OMA" id="IFEEHFF"/>
    <dbReference type="OrthoDB" id="372840at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="335"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="382" mass="46913" checksum="3E2B71D599744947" modified="2017-02-15" version="1">MSLSYANIYIFYFILIIIIKIKCMKIHATYEKNGNMRLLNIISNNFRRKTKLSLNILDKINKYKKENLFEDIVYANKKKSIINTFYKEIIKRDKKIIVRKLNEIINKQQRINPPLFFNESVHCFHKNFFYYYVFFYILGINTNTYIPKKIHKFFINKLKIELLNNAVCNLNLFKKIYIWNEEIISNIYKKYFKIYEKELYVIIDQHLNHDEYYQSRWKEYDNKEFTVPLLNTYAILLFNTFNKNFYIKSLHTIKRLIQTNIKIYILKNYINDLYSVKKILYTYKVFFKLSIKKNMIPLFCTLQDNLKLNKNFEYFFDEIIKQVDVDVPNLKIINLFNLFVILFKLLLNKITQLLFYSTLIYMQKKIHERKKFIKDIYSFPFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT77</accession>
    <name>A0A1J1GT77_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Large ribosomal subunit protein bL21m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00293900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528542.1">
        <property type="nucleotide sequence ID" value="XM_028671939.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT77"/>
    <dbReference type="GeneID" id="39731472"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00293900"/>
    <dbReference type="OMA" id="DLWSNRW"/>
    <dbReference type="OrthoDB" id="5994at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028909">
        <property type="entry name" value="bL21-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036164">
        <property type="entry name" value="bL21-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21349">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21349:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL21M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00829">
        <property type="entry name" value="Ribosomal_L21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141091">
        <property type="entry name" value="L21p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00044129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="385" mass="46362" checksum="32018E0927BA7302" modified="2017-02-15" version="1">MLGKHRKRKINPPLFPIHPNEEKKKNLNNFITYKDLKIRWRNTSKNYRKKVTIARKWKNLHCLLPSNKNSCIFILHKNLPFTRFKKNNSNLEKDNINISLKNKINEEVPQDNSSILVKGDNETIVKKNYINYDLKEKNNKMGRRRKINNILMIKRPGKKDEEDEEKENSNLFNQEKIHIEEQNYYEKPPKELEYLLNNDKKDMFCIFKSNFINEHKVTIGDIVQTERLHRKKAGDIVYFGTVLFVGTKNFSIIGKPTVPYCKVKAVIEQITLSQEILSFRYKKVRRSSRFLRIKHWITILKIEDIIIDLKNEIKDERIKPLQILDLWSNRWLYQKELNFIKFDENKKPLAERIYNLIEHQPNTLHRRGLTECYRFYPDPYIPQSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTK5</accession>
    <name>A0A1J1GTK5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Queuine tRNA-ribosyltransferase, putative</fullName>
            <ecNumber evidence="2">2.4.2.29</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00305600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.29" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528652.1">
        <property type="nucleotide sequence ID" value="XM_028672061.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTK5"/>
    <dbReference type="GeneID" id="39731589"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00305600"/>
    <dbReference type="OMA" id="MAGSRMK"/>
    <dbReference type="OrthoDB" id="27601at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.105">
        <property type="entry name" value="Queuine tRNA-ribosyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050852">
        <property type="entry name" value="Queuine_tRNA-ribosyltrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036511">
        <property type="entry name" value="TGT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002616">
        <property type="entry name" value="tRNA_ribo_trans-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00449">
        <property type="entry name" value="tgt_general"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46064">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46064:SF1">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01702">
        <property type="entry name" value="TGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51713">
        <property type="entry name" value="tRNA-guanine transglycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="tRNA-guanine(15) transglycosylase-like" evidence="1">
        <location>
            <begin position="20"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="396" mass="46760" checksum="6BB4FE6A1CC6BF3D" modified="2017-02-15" version="1">MLFLKMKDEMKYCIKKINDVETPVSTILTNDFLPEFINMELLRKIEKKVILNCPLFEVYNQLDVLEKAKEFFNKKSDKSKNYLDNFCDFEGTYRYMNIRNVLTNNFSININKYITLKYNNSTVVFSIDDFLKCIEIFEPNIFCIPSEEIKINEDIGKKKKIRIINLMDEFLEKIKTMKENSLHNSLCILSIPSTINIHNLITDILNKYNCILDGYLLSGIGYDESNEIRTKYLKNILNVLPDDKLKFIQLSIGNPIEILHSIFNGIDIIETNFPYYLAKNGKAINMNIKMNESNYNSKLHDINLINFKNSENFIIDLNDTKYNFDFSTITNNSPRKETKSYIHHLLKCQELTAHVILTYHNLYIYNLFFKEIQTQIKNNNFLNYISWFVENHNLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTK6</accession>
    <name>A0A1J1GTK6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00299500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528591.1">
        <property type="nucleotide sequence ID" value="XM_028671994.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTK6"/>
    <dbReference type="GeneID" id="39731528"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00299500"/>
    <dbReference type="OMA" id="YHGTELR"/>
    <dbReference type="OrthoDB" id="391665at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="243"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="272"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="329"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="359"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="395" mass="47632" checksum="C7876CE92D1E8235" modified="2017-02-15" version="1">MEEEIMTQKNFSKELLEPLITVSVIFICFYMITSVESPLYFFLRGYIFKAKIFYYEIRKSFTNINYFALIFSSFFFLPYVLNILNYKNVKPIFCVNYNYYENILNYNLKDINIKSIFQNDVSENYLVNFLYSFKFIFHIFFLNDSNLLKTFFTFFFVYILLSLYAKHVNRVIFISSIFMNIVLSGFILVFFLKKFLNIKYNHCGDEAFSFLFLLFFFVSNPYLSSLQYNDRSLHPYHGTEIRFFIHLLFFIKYVTYYENFYEQKALTARHTFIKIIWLVAYYFINNYLPFTFSTNFTISKIFHSNIMDLLSKEIKSNISLFHFNVTSGLPFNYLICKISFFWIPYILLTSNNDNFKYLIILLITTNLIVTCTYLAYTFLPGIILNILLLYYLRKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTT6</accession>
    <name>A0A1J1GTT6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">GPI mannosyltransferase 1</fullName>
            <ecNumber evidence="11">2.4.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">GPI mannosyltransferase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">PIGM</name>
        <name evidence="12" type="ORF">PGAL8A_00311000</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalytic subunit of the glycosylphosphatidylinositol-mannosyltransferase I complex which catalyzes the transfer of the first mannose, via an alpha-1,4 bond from a dolichol-phosphate-mannose (Dol-P-Man) to the glucosaminyl acyl phosphatidylinositol (GlcN-(acyl)PI) intermediate to generate alpha-D-Man-(1-&gt;4)-alpha-D-GlcN-(1-&gt;6)-(1-radyl,2-acyl-sn-glycero-3-phospho)-2-acyl-inositol and participates in the sixth step of the glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the PIGM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="11"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528706.1">
        <property type="nucleotide sequence ID" value="XM_028672122.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTT6"/>
    <dbReference type="GeneID" id="39731643"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00311000"/>
    <dbReference type="OMA" id="MLWFIGQ"/>
    <dbReference type="OrthoDB" id="1741594at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990529">
        <property type="term" value="C:glycosylphosphatidylinositol-mannosyltransferase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051751">
        <property type="term" value="F:alpha-1,4-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004376">
        <property type="term" value="F:GPI mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007704">
        <property type="entry name" value="PIG-M"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12886:SF0">
        <property type="entry name" value="GPI MANNOSYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12886">
        <property type="entry name" value="PIG-M MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05007">
        <property type="entry name" value="Mannosyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 11 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4 11" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="135"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="182"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="250"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="311"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="358"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="382"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="415"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU365064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG95898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="447" mass="53962" checksum="E91E78D04AE7AA8D" modified="2017-02-15" version="1">MSFNIIKKQIQFNIRNKRNFKEINLNFLTKIIYFLGIFLRVIIYYYGLWQDNNLNVKFTDVDYYVFSDAAKYVLSKKSPYERYTYRYTPILAYLMLPNFFIHFSFGKILFSLMDFFVSIIIIKIIKIKYPECKNYVYYVTLWILNPLVIVISSRGNADCIPCLLVLITVLCIYQKKILLSSIFYGLAVNFKIYPIIYSLPLMLYLNRNYLSRNKVLYLKKKNDSFLNCIINVYYIIFQFFSELFKLNYNQLVFSLCSFFTFLTLNIIFYLVYGYEFLYESYIYHLVRRDHRHNFSLFFYIMYLSIEKNSKIIPLITFIPQMILVGLVGFKYAKTNLDLAMFLQTMMFIAMNKVCTSQYFIWCIPFIPIILCSITLDKKNIIIITFAIIFFTFTKSYWLLWAYFLEFKGYNSFLQLFFSSILFVISEMTLCWAFMYMHHREEKIKKNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTW7</accession>
    <name>A0A1J1GTW7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00288000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528491.1">
        <property type="nucleotide sequence ID" value="XM_028671883.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTW7"/>
    <dbReference type="GeneID" id="39731413"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00288000"/>
    <dbReference type="OrthoDB" id="371614at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="333"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="542"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="619"/>
            <end position="646"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="656" mass="78577" checksum="95559F6F93A72EF3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUE5</accession>
    <name>A0A1J1GUE5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00334200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528932.1">
        <property type="nucleotide sequence ID" value="XM_028672373.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUE5"/>
    <dbReference type="GeneID" id="39731872"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00334200"/>
    <dbReference type="OMA" id="EKHRIYQ"/>
    <dbReference type="OrthoDB" id="386301at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="19"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="168" mass="20319" checksum="067868185339D8DA" modified="2017-02-15" version="1">MAEFYENDEDVLQMIQQIKKITKESKRKFENEIDNLVEDTKINLINNVNEEKNLIEKERDEKLKKLRENITKHEKNIKEKHRLYQKLKSELADVANNYKNKIKDFYKETENFMKAYESDKKKLEELEDEEWKELNNQCIEILNKTKSNMCATKDETNEKLRKALKSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUE9</accession>
    <name>A0A1J1GUE9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Histone H2B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00332400</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the histone H2B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528914.1">
        <property type="nucleotide sequence ID" value="XM_028672353.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUE9"/>
    <dbReference type="GeneID" id="39731854"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00332400"/>
    <dbReference type="OMA" id="LLXGELA"/>
    <dbReference type="OrthoDB" id="10036053at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22910">
        <property type="entry name" value="HFD_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000043">
        <property type="entry name" value="Histone H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000558">
        <property type="entry name" value="Histone_H2B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055333">
        <property type="entry name" value="HISTONE_H2B_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23428">
        <property type="entry name" value="HISTONE H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00621">
        <property type="entry name" value="HISTONEH2B"/>
    </dbReference>
    <dbReference type="SMART" id="SM00427">
        <property type="entry name" value="H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00357">
        <property type="entry name" value="HISTONE_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 8" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="10">
        <location>
            <begin position="14"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG96109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="118" mass="13297" checksum="D7F74500CC4010E7" modified="2017-02-15" version="1">MVSKKPVKAKKSSTAAPDAKKKRKKSRYDSYGLYIFKVLKQVHPDTGISRRSMNIMNSFLVDTFEKIATEASRLCKYTRRDTLSSREIQTAIRLVLPGELAKHAVSEGTKAVTKFTSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUF7</accession>
    <name>A0A1J1GUF7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MARVEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00333200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528922.1">
        <property type="nucleotide sequence ID" value="XM_028672362.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUF7"/>
    <dbReference type="GeneID" id="39731862"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00333200"/>
    <dbReference type="OMA" id="STIWMFV"/>
    <dbReference type="OrthoDB" id="374371at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="132" mass="14503" checksum="B02AB56C26E9D622" modified="2017-02-15" version="1">MAISRDIATSIFGLIASSLLFAVAGTFNELTGVVGCFIFLGGAFTIYTIITFLIPSMKNSRDLVFSYGVSTACMFVACIMTFIILTYFYTKIHCHYGSKYCARLVFGSIFGFLSSGFFLVSSMLSLKIAHVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUJ4</accession>
    <name>A0A1J1GUJ4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00340100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528988.1">
        <property type="nucleotide sequence ID" value="XM_028672436.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUJ4"/>
    <dbReference type="GeneID" id="39731931"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00340100"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="111" mass="13497" checksum="76D25C48D57CAA8C" modified="2017-02-15" version="1">MNLHKFLPIRNIFFSSKNTIHSLKKFSFFKKISENDFCKPLVNNELTPIKSDIILKNYFFFNNMFLFNIKIKDNSIVKKPAQELYFKNKKTKLALRRKRKRMGERVSLRYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUR7</accession>
    <name>A0A1J1GUR7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00343900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529026.1">
        <property type="nucleotide sequence ID" value="XM_028672478.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUR7"/>
    <dbReference type="GeneID" id="39731969"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00343900"/>
    <dbReference type="OMA" id="KISGFIW"/>
    <dbReference type="OrthoDB" id="361576at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="128" mass="15335" checksum="659F456DE65A0720" modified="2017-02-15" version="1">MICIFYHLIIFLVGYLLPIGLSFHGWNNKKYDMVEYYLKYIFFFVIFENMITPLVGTIIYKINSSVWCFLHLSIYIILITPKFNYLYLIYETVSKVTNQNNLTSLWNNYLVKPLNDKINKVIKKVKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUX8</accession>
    <name>A0A1J1GUX8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S acidic ribosomal protein P0</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00357100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Ribosomal protein P0 is the functional equivalent of E.coli protein L10.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529158.1">
        <property type="nucleotide sequence ID" value="XM_028672624.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUX8"/>
    <dbReference type="GeneID" id="39732101"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00357100"/>
    <dbReference type="OMA" id="DMNPFKL"/>
    <dbReference type="OrthoDB" id="10259902at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05795">
        <property type="entry name" value="Ribosomal_P0_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.105.20:FF:000001">
        <property type="entry name" value="60S acidic ribosomal protein P0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.105.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050323">
        <property type="entry name" value="Ribosomal_protein_uL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_uL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040637">
        <property type="entry name" value="Ribosomal_uL10-like_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043164">
        <property type="entry name" value="Ribosomal_uL10-like_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_uL10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030670">
        <property type="entry name" value="uL10_eukaryotes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45699">
        <property type="entry name" value="60S ACIDIC RIBOSOMAL PROTEIN P0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45699:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00428">
        <property type="entry name" value="Ribosomal_60s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17777">
        <property type="entry name" value="RL10P_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039087">
        <property type="entry name" value="L10E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="Ribosomal protein L10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL10-like insertion" evidence="6">
        <location>
            <begin position="111"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="279"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="286"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR039087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="316" mass="34999" checksum="A2209F96ECB5A604" modified="2017-02-15" version="1">MAKLSKAQKKQMYIDKLSTLIQQYTKILIVHVDNVGSDQMATVRQSLRGKAVILMGKNTRIRTALKKNLQAVPQIEKLLPLVKLNMGFVFCNDDLSEVRKIILENRSPAPARLGVIAPIDVFIPPGPTGMDPSHTSFFQSLGISTKIVKGQIEIQEKVHLIKQGEKVTASSATLLQKFNMKPFSYGVEVKTVYDDGVIYDANVLDITEEDILKKFSKGVSNVAALSRAVGIITEASYPHVFVEAFKNIVSLVIDSDYTFPLMQNIKNMVENPQAYVAAAPAASATKTEEPKKEEAKKQEEEEEDDEDGFVGFGMFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV32</accession>
    <name>A0A1J1GV32_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">tRNA (guanine-N(7)-)-methyltransferase</fullName>
            <ecNumber evidence="9">2.1.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">tRNA (guanine(46)-N(7))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">tRNA(m7G46)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00354000</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>guanosine(46) in tRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(46) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42708"/>
            <dbReference type="Rhea" id="RHEA-COMP:10188"/>
            <dbReference type="Rhea" id="RHEA-COMP:10189"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74480"/>
            <dbReference type="EC" id="2.1.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">tRNA modification; N(7)-methylguanine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.33" evidence="9"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529127.1">
        <property type="nucleotide sequence ID" value="XM_028672590.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV32"/>
    <dbReference type="GeneID" id="39732070"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00354000"/>
    <dbReference type="OMA" id="QCGETVQ"/>
    <dbReference type="OrthoDB" id="47276at2759"/>
    <dbReference type="UniPathway" id="UPA00989"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043527">
        <property type="term" value="C:tRNA methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008176">
        <property type="term" value="F:tRNA (guanine(46)-N7)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03055">
        <property type="entry name" value="tRNA_methyltr_TrmB_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025763">
        <property type="entry name" value="Trm8_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003358">
        <property type="entry name" value="tRNA_(Gua-N-7)_MeTrfase_Trmb"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00091">
        <property type="entry name" value="tRNA (guanosine(46)-N7)-methyltransferase TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23417">
        <property type="entry name" value="3-DEOXY-D-MANNO-OCTULOSONIC-ACID TRANSFERASE/TRNA GUANINE-N 7 - -METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23417:SF16">
        <property type="entry name" value="TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02390">
        <property type="entry name" value="Methyltransf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51625">
        <property type="entry name" value="SAM_MT_TRMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 9" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2 9" id="KW-0820">tRNA-binding</keyword>
    <feature type="active site" evidence="9">
        <location>
            <position position="210"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="154"/>
            <end position="155"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="187"/>
            <end position="188"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="285"/>
            <end position="287"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG96322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="306" mass="37074" checksum="4AA55C945D0A4F61" modified="2017-02-15" version="1">MKKDKTPCKRYYRQRAHCNPLSDSYIKYPLNYNYVDWKLHYPYYFKNENIIENKEKKNENALKDIEYNNDNDNSKDQTDRNIINKETNKEINDLMGDVNKLYLNTNKHPITYDKIICSKSNNHEVKFLDIGCGYGGLLFALSKLFNDKLILGLEIRDKITNYVGEKIISYRNNHYPYYNNISIIRTNAIKFLPNYIKKNQIEKIFFCFPDPHFKKHNWRRRIITLENLSLYYHLLQKNGLIYFITDVFTLHLWVKYCFYKFPYFKLLSHEEYKDDICIKLIHESSEESKKVKRNNQNMYFCIAKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV90</accession>
    <name>A0A1J1GV90_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mitochondrial ribosomal protein L2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00360200</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529183.1">
        <property type="nucleotide sequence ID" value="XM_028672652.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV90"/>
    <dbReference type="GeneID" id="39732132"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00360200"/>
    <dbReference type="OMA" id="TAQRGNC"/>
    <dbReference type="OrthoDB" id="1298661at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000001">
        <property type="entry name" value="50S ribosomal protein L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.950.10:FF:000003">
        <property type="entry name" value="50S ribosomal protein L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000029">
        <property type="entry name" value="50S ribosomal protein L2, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.950.10">
        <property type="entry name" value="Ribosomal protein L2, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002171">
        <property type="entry name" value="Ribosomal_uL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005880">
        <property type="entry name" value="Ribosomal_uL2_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022669">
        <property type="entry name" value="Ribosomal_uL2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014726">
        <property type="entry name" value="Ribosomal_uL2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022666">
        <property type="entry name" value="Ribosomal_uL2_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01171">
        <property type="entry name" value="rplB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691:SF5">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691">
        <property type="entry name" value="RIBOSOMAL PROTEIN L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03947">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00181">
        <property type="entry name" value="Ribosomal_L2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01383">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01382">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0934">Plastid</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 9" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL2 RNA-binding" evidence="8">
        <location>
            <begin position="90"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL2 C-terminal" evidence="7">
        <location>
            <begin position="172"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="271"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="277"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG96378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="333" mass="37755" checksum="4AE6A89E6FD4EDA5" modified="2017-02-15" version="1">MNKLTFGLKNNILIKRFFSNYYSPNIKRNVPEYIDFETFFPKKDIKPDVLSAFTIAKQQRLEKLLENNPLVLYKGRVIKNLSCHKIKNSGRNNVGKITTRHRGGGHVQRLRFIDFKRSRKDIYSTVLRIEYDPSRSAHIALIQYEDGVLSYILAPLLLRPGDKVIASKYANINPGNCLPLKNIPVGSIIHNIELRPGAGGQFIRAAGTYATILSKDSQYATIKLKSTEIRKFPLECWATIGQVSNLQRHMRILGKAGVNRWLGKRPVVRGVAMNPSKHPHGGGTSKKHTKRPKCSLWGKCRDGFKTRSKKKPLGLIIRRNICGRLQKKYGVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVA8</accession>
    <name>A0A1J1GVA8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">P-loop containing nucleoside triphosphate, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00263800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528045.1">
        <property type="nucleotide sequence ID" value="XM_028671387.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731167"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00263800"/>
    <dbReference type="OrthoDB" id="1879at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001749">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048966">
        <property type="entry name" value="Aquarius_b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032174">
        <property type="entry name" value="Aquarius_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF5">
        <property type="entry name" value="RNA HELICASE AQUARIUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16399">
        <property type="entry name" value="Aquarius_N_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21143">
        <property type="entry name" value="Aquarius_N_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA helicase aquarius N-terminal" evidence="4">
        <location>
            <begin position="621"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="domain" description="RNA helicase aquarius beta-barrel" evidence="5">
        <location>
            <begin position="992"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="2">
        <location>
            <begin position="1548"/>
            <end position="1670"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="2">
        <location>
            <begin position="1874"/>
            <end position="2071"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="3">
        <location>
            <begin position="2080"/>
            <end position="2272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1199"/>
            <end position="1251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1426"/>
            <end position="1445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1199"/>
            <end position="1209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1432"/>
            <end position="1442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF21143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2338" mass="281970" checksum="2928E5AC47F7D6BA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVJ3</accession>
    <name>A0A1J1GVJ3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PIR-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00413300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000065">
        <property type="protein sequence ID" value="CRG96551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529356.1">
        <property type="nucleotide sequence ID" value="XM_028672844.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVJ3"/>
    <dbReference type="GeneID" id="39732663"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00413300"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="282"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="159"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="207"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="379" mass="42133" checksum="0BEB0FA54816C9FA" modified="2017-02-15" version="1">MMIIYIYLLVCIFQYFYSINFETGKNNLKTELCLRSGRVLAERQQGTRSRNVRSTRDIKGNLKVWLDTIEEGLFDRIEELKSNLTLRNAMDFSQWMNKKSDNITYVLNRVPDPIEKKILNDTLTSWRKLTDKVLLDQISDTYVHRMVIPQKVATTNGLSITSATSNPTSSSNSTSSPTPTQSYNLTPFPISTTSPVLTISPTVLPSASDLSPTSDLSSTTSDSHIHTTTSSTNDTSESPTVFPTNEINSTTSLTNNPTALIPTQHGGGLTGATCTGLLCAPAFAALPISVVLLGVVLVFVLLYMYTPVGKFLGRDKPKKKKAKKRLNEIPMECINSPQLLKVKKKENAKRSVLDRFLRAFGYDKNFPYIDEEIASDQVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVL6</accession>
    <name>A0A1J1GVL6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Leucine-rich repeat protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">LRR10</name>
        <name evidence="4" type="ORF">PGAL8A_00373900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529319.1">
        <property type="nucleotide sequence ID" value="XM_028672803.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVL6"/>
    <dbReference type="GeneID" id="39732269"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00373900"/>
    <dbReference type="OMA" id="HLKYINM"/>
    <dbReference type="OrthoDB" id="271226at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050836">
        <property type="entry name" value="SDS22/Internalin_LRR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46652">
        <property type="entry name" value="LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46652:SF3">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00019">
        <property type="entry name" value="LEURICHRPT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="277" mass="32590" checksum="B2E67988A8248696" modified="2017-02-15" version="1">MKALSKNSINENIKSTNNENELNNKNTINNFLLHVKNGLTQLEKTLSGEGYAFSNLICKNKNIDNIPKEIEKYRHLKYINMSNNKISDIKNLCLLPNIVFLDISFNVIENLKDFKKNCLENCLYINISHNLIKNIEKICLKSIIEFDLSYNNISNFNIYFSNTIKKLNLSNNYIKNLSFKNKLTNLEFLDLSSNPLENLDFYENTPNLNFLKINNISTLEKDKLKSLNNFKFLEYLDMDNYFYFKDISYKEIKKIIITNTKDINLLKFNGRRILNKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVM2</accession>
    <name>A0A1J1GVM2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TFIIS N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00418300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529406.1">
        <property type="nucleotide sequence ID" value="XM_028672900.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732714"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00418300"/>
    <dbReference type="OMA" id="PCLFEDK"/>
    <dbReference type="OrthoDB" id="378545at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.10">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035441">
        <property type="entry name" value="TFIIS/LEDGF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017923">
        <property type="entry name" value="TFIIS_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08711">
        <property type="entry name" value="Med26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47676">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51319">
        <property type="entry name" value="TFIIS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TFIIS N-terminal" evidence="4">
        <location>
            <begin position="345"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="250"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="442"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="555"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1535" mass="178995" checksum="01C3EFD9E0AC412A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVW0</accession>
    <name>A0A1J1GVW0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">DNA-directed RNA polymerase subunit beta</fullName>
            <ecNumber evidence="4 14">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">PGAL8A_00362200</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 14">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">In plastids the minimal PEP RNA polymerase catalytic core is composed of four subunits: alpha, beta, beta', and beta''. When a (nuclear-encoded) sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Apicoplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="4 14"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529203.1">
        <property type="nucleotide sequence ID" value="XM_028672674.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732152"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00362200"/>
    <dbReference type="OMA" id="FNISIER"/>
    <dbReference type="OrthoDB" id="10248617at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020011">
        <property type="term" value="C:apicoplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.270.10:FF:000006">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.270.10:FF:000012">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1100.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="entry name" value="DNA-directed RNA polymerase, subunit 2, domain 6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1800.10">
        <property type="entry name" value="RNA polymerase alpha subunit dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="entry name" value="RNA polymerase Rpb2, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0933">Apicoplast</keyword>
    <keyword evidence="6 14 20" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="9 14" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-0934">Plastid</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 14" id="KW-0804">Transcription</keyword>
    <keyword evidence="8 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNA polymerase beta subunit protrusion" evidence="18">
        <location>
            <begin position="83"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="19">
        <location>
            <begin position="591"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase subunit 2 hybrid-binding" evidence="16">
        <location>
            <begin position="934"/>
            <end position="1230"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase subunit 2 hybrid-binding" evidence="16">
        <location>
            <begin position="1299"/>
            <end position="1381"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="17">
        <location>
            <begin position="1383"/>
            <end position="1487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1278"/>
            <end position="1298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="1280"/>
            <end position="1294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022887"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00026088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU363031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="CRG96398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1498" mass="174302" checksum="F0F3099BAB55B7DF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVY1</accession>
    <name>A0A1J1GVY1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fam-h protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00265300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000034">
        <property type="protein sequence ID" value="CRG95450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528261.1">
        <property type="nucleotide sequence ID" value="XM_028671627.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVY1"/>
    <dbReference type="GeneID" id="39731182"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00265300"/>
    <dbReference type="OMA" id="MSASKIY"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="216" mass="24881" checksum="C008E281D23949F0" modified="2017-02-15" version="1">MRNLIISNVTSKSRNNTHIAENFIIEDISTSRKYHAKGKINKFIFFIKVFLFTLLNIQRSLNEKCSLKNNLNLGAKRFLAENKEITELTNDELKTRLSDLLKTLEEKNTKDSNVQSDVVQGKVETIEIENENSVSRREKSNKKINSRDLMEKYKKCMRLFNLASIILLPVLSMTVSIVAFTSTDQKYINISNIITSLYLVLNSILLSDLRSNKDNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW55</accession>
    <name>A0A1J1GW55_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Plasmodium RESA N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00413900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000068">
        <property type="protein sequence ID" value="CRG96557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529361.1">
        <property type="nucleotide sequence ID" value="XM_028672849.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW55"/>
    <dbReference type="GeneID" id="39732669"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00413900"/>
    <dbReference type="OMA" id="WIHIERT"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="209" mass="25555" checksum="402C1143A3855756" modified="2017-02-15" version="1">MKNYPIYPYIHKGGTTKKKGSIVRCLFNQKSQSVSIIKFNKEYLRILAEEEEEIKNKILKMDNPYGIYSIHFNIKTGALIERMLSDWQNLCNDLRKKFSSYEREWEVEHFDQWYNKISDDIKSFHEEVLAEYIPIWVSRHNDKECYKYFEKKRKELSKLCNILEEWFMKYIKKCKDEWYPSNCKNVPTFYKSIFKNKKKDYMPLINNQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWA0</accession>
    <name>A0A1J1GWA0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CS domain protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00439800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529620.1">
        <property type="nucleotide sequence ID" value="XM_028673137.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWA0"/>
    <dbReference type="GeneID" id="39732931"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00439800"/>
    <dbReference type="OMA" id="HDFVHKG"/>
    <dbReference type="OrthoDB" id="515366at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06467">
        <property type="entry name" value="p23_NUDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037898">
        <property type="entry name" value="NudC_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12356">
        <property type="entry name" value="NUCLEAR MOVEMENT PROTEIN NUDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12356:SF18">
        <property type="entry name" value="NUDC DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="1">
        <location>
            <begin position="14"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="156" mass="18370" checksum="E56EDA9756FF7CB1" modified="2017-02-15" version="1">MGEIYNKRHKYVNNGVLIYEWEQSIDEINIYINMSSKIVNKNDLNIEIKSKRIRIGLKKMKSFLDDELFSIIDEDCSYWFIEDNNLHILLTKAKKGEVWSSVFKGHKNLNAIDEDNTKKKILLERFQQEYPNFDFSSASFNGQVPDARTFMGGIKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWE0</accession>
    <name>A0A1J1GWE0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00437300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529594.1">
        <property type="nucleotide sequence ID" value="XM_028673108.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWE0"/>
    <dbReference type="GeneID" id="39732905"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00437300"/>
    <dbReference type="OMA" id="HNENNIR"/>
    <dbReference type="OrthoDB" id="378840at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1183" mass="140294" checksum="D07FCB3F58A7EEDB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWP9</accession>
    <name>A0A1J1GWP9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00454900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529772.1">
        <property type="nucleotide sequence ID" value="XM_028673305.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733082"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00454900"/>
    <dbReference type="OMA" id="NQYNNHD"/>
    <dbReference type="OrthoDB" id="372810at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="79"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="135"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1437"/>
            <end position="1484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1817"/>
            <end position="1842"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1868"/>
            <end position="1993"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2095"/>
            <end position="2259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2389"/>
            <end position="2422"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1552"/>
            <end position="1579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="146"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1437"/>
            <end position="1461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1475"/>
            <end position="1484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1817"/>
            <end position="1828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1829"/>
            <end position="1842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1876"/>
            <end position="1993"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2104"/>
            <end position="2128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2129"/>
            <end position="2157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2166"/>
            <end position="2258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2391"/>
            <end position="2421"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="2600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2600" mass="301912" checksum="890D32D442102B96" modified="2017-02-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWZ9</accession>
    <name>A0A1J1GWZ9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00441900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529641.1">
        <property type="nucleotide sequence ID" value="XM_028673160.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWZ9"/>
    <dbReference type="GeneID" id="39732952"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00441900"/>
    <dbReference type="OMA" id="FTRLHTC"/>
    <dbReference type="OrthoDB" id="372171at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="313" mass="37940" checksum="6BC7D809C8A7D7D0" modified="2017-02-15" version="1">MGNFIGFKEKNKNIENINIFEKRYGYNLNDLHSYIYKINLPLKPPYINYVLQEKNRKTENFTKEHLNNEEEKKLNNTSDPVDLYKNYERENINNSNNIYSNKLIINNKEPNEKYDDKYVHISYDNNYEYDLNKNNIYTEDNISDYILQHTNTFSNKNKINKTYVNLCLNYYNNLNTCIIKKYEKNVQNKKYKFTRLHTCKPHYVLFSRCIKYRDKKLMKEIKKIELNYFNSLNSTNKLSYLNEFLTNLNYHEYVISKLYDGVEKIKINKELNELKERYNNILKHSESNGEKLPNINEQKRKTNSNKKHILLNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX79</accession>
    <name>A0A1J1GX79_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00282100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528432.1">
        <property type="nucleotide sequence ID" value="XM_028671817.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX79"/>
    <dbReference type="GeneID" id="39731354"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00282100"/>
    <dbReference type="OMA" id="LLFWNRS"/>
    <dbReference type="OrthoDB" id="371164at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="123" mass="14755" checksum="3D8E026BA6212AF9" modified="2017-02-15" version="1">MNKIAYLRKFISNNFFFKNMLIADMKIKKSCIVENYEKNVRKSDFICSNLNIRKENEIKNHSFSFFFNSEFLIDKKFLNKKKEEVLCFWNRSPGARYPKKANNGARPDCRSVRKIRKRLKTGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXA8</accession>
    <name>A0A1J1GXA8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Bax inhibitor 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00469200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the BI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529914.1">
        <property type="nucleotide sequence ID" value="XM_028673464.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXA8"/>
    <dbReference type="GeneID" id="39733225"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00469200"/>
    <dbReference type="OMA" id="FHVADWD"/>
    <dbReference type="OrthoDB" id="7933078at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd10428">
        <property type="entry name" value="LFG_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006214">
        <property type="entry name" value="Bax_inhibitor_1-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291">
        <property type="entry name" value="BAX INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291:SF47">
        <property type="entry name" value="TRANSMEMBRANE BAX INHIBITOR MOTIF CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01027">
        <property type="entry name" value="Bax1-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="233"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="269"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="295" mass="33199" checksum="7216EAD787A6FB68" modified="2017-02-15" version="1">MYNANGRDSANPPPPAQNYGAVYNHGNYSYEQNKLNNNMYDIPIPNQQKEYCYDAPTNATANGGLYDEFSLNEFSSTKIRHGFIRKVYSILSLQLLITFGFSALTVLYDPVKTFVRSNDVLFLVLGILLSLPILITLACYPTLARKYPSNYLILLLITIGMTLIVSLATARTNSEIFFYAFGITAAVVIGLTIFSFQTKWDFTGWHVFLFMAFLILFVLGIITIFVRSKIMNLVYSGVSAFILSISIIVDTQLIIGGKHKKYEFSIDDYIFATLALYMDIVNLFLSILSIISNTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXM3</accession>
    <name>A0A1J1GXM3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Claudin-like apicomplexan microneme protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00489500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530118.1">
        <property type="nucleotide sequence ID" value="XM_028673691.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXM3"/>
    <dbReference type="GeneID" id="39733428"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00489500"/>
    <dbReference type="OMA" id="FYIFMIT"/>
    <dbReference type="OrthoDB" id="330952at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="412" mass="47871" checksum="008A6257CDEB7715" modified="2017-02-15" version="1">MGRAHKARGKVELPKKSSRFLNVIMVLAFLSAVPQILTTFMLSWRVADPIKYTFMFRGSRHYITFDVTWYGLYRVLYDNKHSETWSQRVDNMKNRGNLVIQQGRNSESAGSLSLWTSLCPEACREAIMKRIESYERVAFISLVLLCSIILSCTIVLLSIGWSILFYKNIFILMGCFILSFIINAGVGGYWYYETDMSWNIVSGVQQYPFPRCSYCFYIFMITTVMYALCFLGLLILDLVNKNKEKKSHMDQINMHNRDPVNAKGMYQPLFGNPSNMMMQRSASFSNLMPFDKGMNNEYPNFMLYNKMNMNPMGTFSSFRNMPPGMPPNMQPNMPPNMQPNMPSHMNPNFFPQVSRQYSYSGSPSFQQNFQNFDNFSMRNMPSMSDLNFARQYSGMNYSNMNNPFNSQKPFKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXM5</accession>
    <name>A0A1J1GXM5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tetratricopeptide repeat protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00462600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529849.1">
        <property type="nucleotide sequence ID" value="XM_028673392.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXM5"/>
    <dbReference type="GeneID" id="39733159"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00462600"/>
    <dbReference type="OMA" id="KREDVKY"/>
    <dbReference type="OrthoDB" id="1872379at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052769">
        <property type="entry name" value="TPR_domain_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46014">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46014:SF1">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="490"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="335"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="127"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="294"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="496"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="335"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="370"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="386"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="591" mass="69659" checksum="7C49B69B7CC6B471" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXT7</accession>
    <name>A0A1J1GXT7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">S-antigen protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00495100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">S antigens are soluble heat-stable proteins present in the sera of some infected individuals.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Parasitophorous vacuole</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530174.1">
        <property type="nucleotide sequence ID" value="XM_028673752.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXT7"/>
    <dbReference type="GeneID" id="39733484"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00495100"/>
    <dbReference type="OMA" id="IQADSHT"/>
    <dbReference type="OrthoDB" id="392935at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020003">
        <property type="term" value="C:symbiont-containing vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008825">
        <property type="entry name" value="S-antigen"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05756">
        <property type="entry name" value="S-antigen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012362518" description="S-antigen protein" evidence="6">
        <location>
            <begin position="20"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="domain" description="S-antigen" evidence="7">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="104"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="146"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="167"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="204"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="242"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="263"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="301"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="336"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="350"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="367"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="442"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="479"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="568" mass="63085" checksum="CCB1979B2399498B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXZ0</accession>
    <name>A0A1J1GXZ0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00500600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530235.1">
        <property type="nucleotide sequence ID" value="XM_028673820.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXZ0"/>
    <dbReference type="GeneID" id="39733539"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00500600"/>
    <dbReference type="OrthoDB" id="441812at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF137">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="606"/>
            <end position="806"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1084" mass="130816" checksum="24319A76C23BA1BF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY21</accession>
    <name>A0A1J1GY21_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00311700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528712.1">
        <property type="nucleotide sequence ID" value="XM_028672128.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY21"/>
    <dbReference type="GeneID" id="39731650"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00311700"/>
    <dbReference type="OMA" id="NISHMEG"/>
    <dbReference type="OrthoDB" id="392213at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="209" mass="24696" checksum="3E001FE896CF4F38" modified="2017-02-15" version="1">MKENPSISSKFKKTEDELILDSQEGFLKYEIKEKSEFSNENYLKNYAIEESNINLTNNNKDKNESLNEEEKDKQNDIINSQNISNNILIPKVIKKYVNITHKEEVVSYIYTLVSYKNYNIFFITHNGKFASWIYTYNVILPFSVDQETEIIFGERNYPLLEIFCSKFMKDHASLLKYKPIIFALSIYKMSFDDKDILNQIFVNLSNIIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYA4</accession>
    <name>A0A1J1GYA4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ATP-dependent RNA helicase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00319700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528792.1">
        <property type="nucleotide sequence ID" value="XM_028672218.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYA4"/>
    <dbReference type="GeneID" id="39731730"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00319700"/>
    <dbReference type="OMA" id="KLYMYQY"/>
    <dbReference type="OrthoDB" id="10256233at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="198"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="539"/>
            <end position="678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="879" mass="104455" checksum="2F4625E30418D720" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYP5</accession>
    <name>A0A1J1GYP5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 subunit A</fullName>
            <shortName evidence="5">eIF3a</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 subunit 10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00527400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the eIF-3 subunit A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530499.1">
        <property type="nucleotide sequence ID" value="XM_028674114.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733807"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00527400"/>
    <dbReference type="OMA" id="EHITNKR"/>
    <dbReference type="OrthoDB" id="1938156at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071540">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex, eIF3e"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071541">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex, eIF3m"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043614">
        <property type="term" value="C:multi-eIF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002188">
        <property type="term" value="P:translation reinitiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.860">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.10">
        <property type="entry name" value="UVR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03000">
        <property type="entry name" value="eIF3a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027512">
        <property type="entry name" value="EIF3A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054711">
        <property type="entry name" value="eIF3a_PCI_TPR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14005:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14005">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3, THETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22591">
        <property type="entry name" value="eIF3a_PCI_TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 8" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="PCI" evidence="7">
        <location>
            <begin position="394"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="282"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="926"/>
            <end position="1290"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="660"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="289"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="325"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="926"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1013"/>
            <end position="1281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1315" mass="159183" checksum="3BA31DDAFE3BDD8F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYU0</accession>
    <name>A0A1J1GYU0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00531600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530539.1">
        <property type="nucleotide sequence ID" value="XM_028674158.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYU0"/>
    <dbReference type="GeneID" id="39733849"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00531600"/>
    <dbReference type="OMA" id="RFSHQCV"/>
    <dbReference type="OrthoDB" id="383635at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="137" mass="17015" checksum="047F2F497786189A" modified="2017-02-15" version="1">MLKSSFETLLKLSQQCAKNCFKNKNEILSSKKIYFSDLVNKRYKKFNFKYLSFPFLKYNFSFTFNKNISTKRRRYFKIRKHQKKKYKKKRMGLSTIPWIPTKEKIRTYKLPRQSKLINKRFMRDKKGGRRYRLKKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYW4</accession>
    <name>A0A1J1GYW4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">AP-1 complex subunit mu-1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">AP1M1</name>
        <name evidence="7" type="ORF">PGAL8A_00507600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the adaptor complexes medium subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530304.1">
        <property type="nucleotide sequence ID" value="XM_028673897.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYW4"/>
    <dbReference type="GeneID" id="39733609"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00507600"/>
    <dbReference type="OMA" id="HSRLEIM"/>
    <dbReference type="OrthoDB" id="10259133at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030131">
        <property type="term" value="C:clathrin adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09250">
        <property type="entry name" value="AP-1_Mu1_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14835">
        <property type="entry name" value="AP1_Mu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000002">
        <property type="entry name" value="AP-2 complex subunit mu, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1170">
        <property type="entry name" value="Mu homology domain, subdomain B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050431">
        <property type="entry name" value="Adaptor_comp_med_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001392">
        <property type="entry name" value="Clathrin_mu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018240">
        <property type="entry name" value="Clathrin_mu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10529">
        <property type="entry name" value="AP COMPLEX SUBUNIT MU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00928">
        <property type="entry name" value="Adap_comp_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005992">
        <property type="entry name" value="Clathrin_mu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00314">
        <property type="entry name" value="CLATHRINADPT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00990">
        <property type="entry name" value="CLAT_ADAPTOR_M_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00991">
        <property type="entry name" value="CLAT_ADAPTOR_M_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MHD" evidence="6">
        <location>
            <begin position="168"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR005992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="436" mass="50689" checksum="5BD98371D8EC5F4A" modified="2017-02-15" version="1">MACISAIFIIDLKGKVIINRNYRGEVNVNLTEVFYNCVIDQEDNLIKPIFHVNGLTYCWVAHNNIYILAVTRKNSNATLIITFLYKLIQVLKDYFKVLEEESIKDNFVITYELLDEMIDNGFPQLSEVKILREYIKNKAHQLTVNNIKIPSAITNSVSWRNEGIKYKKNEIFLDVIESLNIIISSNGTVLRSEILGCLKMKSYLSGMPELKLGLNDKLLFNKNLNNYPNSSNNINSKAKLVELEDIKFHQCVRLSKFENDRTISFIPPDGIFNLMTYRLSTHVKPLFWLDINISKKSLTKIEYIVKAKSQFKNKSIANNVEFHFPVPADVDSPHFQTYIGNVKYYPDKDILIWKIKQFQGQKEYIMNAQFGLPSIVSNENKDLYYKRPVNVKFEIPYFTVSGITVRYLKIIEKSGYQALPWVRYITQNGDYQLRMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ14</accession>
    <name>A0A1J1GZ14_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MMS19 nucleotide excision repair protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00026200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MET18/MMS19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530627.1">
        <property type="nucleotide sequence ID" value="XM_028674256.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728785"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00026200"/>
    <dbReference type="OMA" id="KIEDWHC"/>
    <dbReference type="OrthoDB" id="342900at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097361">
        <property type="term" value="C:cytosolic [4Fe-4S] assembly targeting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039920">
        <property type="entry name" value="MMS19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029240">
        <property type="entry name" value="MMS19_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12891">
        <property type="entry name" value="DNA REPAIR/TRANSCRIPTION PROTEIN MET18/MMS19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12891:SF0">
        <property type="entry name" value="MMS19 NUCLEOTIDE EXCISION REPAIR PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14500">
        <property type="entry name" value="MMS19_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="922"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1023"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1061"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1302"/>
            <end position="1321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="2289"/>
            <end position="2312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="2352"/>
            <end position="2375"/>
        </location>
    </feature>
    <feature type="domain" description="MMS19 N-terminal" evidence="5">
        <location>
            <begin position="283"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="MMS19 N-terminal" evidence="5">
        <location>
            <begin position="417"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1136"/>
            <end position="1156"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="715"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1136"/>
            <end position="1147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU367072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2416" mass="292037" checksum="3D8CB9A077729400" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ49</accession>
    <name>A0A1J1GZ49_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">60S ribosomal subunit protein L24-2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00027200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic ribosomal protein eL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530637.1">
        <property type="nucleotide sequence ID" value="XM_028674267.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ49"/>
    <dbReference type="GeneID" id="39728795"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00027200"/>
    <dbReference type="OMA" id="HNPRKVK"/>
    <dbReference type="OrthoDB" id="10262490at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00472">
        <property type="entry name" value="Ribosomal_L24e_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.170.20:FF:000001">
        <property type="entry name" value="probable ribosome biogenesis protein RLP24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.20">
        <property type="entry name" value="Ribosomal protein L24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038630">
        <property type="entry name" value="L24e/L24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056366">
        <property type="entry name" value="Ribosomal_eL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000988">
        <property type="entry name" value="Ribosomal_eL24-rel_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023442">
        <property type="entry name" value="Ribosomal_eL24_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011017">
        <property type="entry name" value="TRASH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10792">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10792:SF8">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN RLP24-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01246">
        <property type="entry name" value="Ribosomal_L24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00746">
        <property type="entry name" value="TRASH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01073">
        <property type="entry name" value="RIBOSOMAL_L24E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="TRASH" evidence="5">
        <location>
            <begin position="6"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="201" mass="24658" checksum="0D4FA7577FC035D2" modified="2017-02-15" version="1">MRIEKCWYCSGNIYPGHGIFFIRNDANIFRFCRSKCHKHFKAKHNPRKIKWTKIYRKERKKELNYDKTYEFEKIRNEPIKYDRDLYIKTINAIKKIDEIKEKRKLRYYKNRIKESSEKNINLSLNYIKKNPLLLKNTEYENTINDLISNEKEENKMNLIKNTFESEDIIHKEKDDLIKFKADINSIKETTEYKKNKFLELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ52</accession>
    <name>A0A1J1GZ52_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Translation initiation factor IF-2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">IF2a</name>
        <name evidence="8" type="ORF">PGAL8A_00508600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530314.1">
        <property type="nucleotide sequence ID" value="XM_028673908.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ52"/>
    <dbReference type="GeneID" id="39733619"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00508600"/>
    <dbReference type="OMA" id="YVGMFDI"/>
    <dbReference type="OrthoDB" id="361630at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10050">
        <property type="entry name" value="Translation initiation factor IF- 2, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015760">
        <property type="entry name" value="TIF_IF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023115">
        <property type="entry name" value="TIF_IF2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036925">
        <property type="entry name" value="TIF_IF2_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381:SF20">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11987">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52156">
        <property type="entry name" value="Initiation factor IF2/eIF5b, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 8" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="7">
        <location>
            <begin position="199"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="841"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="841"/>
            <end position="854"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1090" mass="128026" checksum="4EE6595120DDCE9D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZN4</accession>
    <name>A0A1J1GZN4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00034200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530705.1">
        <property type="nucleotide sequence ID" value="XM_028674342.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZN4"/>
    <dbReference type="GeneID" id="39728866"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00034200"/>
    <dbReference type="OMA" id="KMESIEF"/>
    <dbReference type="OrthoDB" id="392581at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="734"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1001"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1108"/>
            <end position="1127"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="535"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1260" mass="154572" checksum="35F2EABEC6A784C5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZN9</accession>
    <name>A0A1J1GZN9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Deoxyribodipyrimidine photo-lyase</fullName>
            <ecNumber evidence="3">4.1.99.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">DNA photolyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PGAL8A_00035000</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>cyclobutadipyrimidine (in DNA) = 2 pyrimidine residues (in DNA).</text>
            <dbReference type="EC" id="4.1.99.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA photolyase class-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.3" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530713.1">
        <property type="nucleotide sequence ID" value="XM_028674351.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZN9"/>
    <dbReference type="GeneID" id="39728874"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00035000"/>
    <dbReference type="OMA" id="LIYAYEI"/>
    <dbReference type="OrthoDB" id="496749at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003904">
        <property type="term" value="F:deoxyribodipyrimidine photo-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000719">
        <property type="term" value="P:photoreactive repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.579.10:FF:000002">
        <property type="entry name" value="Deoxyribodipyrimidine photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.579.10">
        <property type="entry name" value="DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032673">
        <property type="entry name" value="DNA_photolyase_2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052219">
        <property type="entry name" value="Photolyase_Class-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10211:SF0">
        <property type="entry name" value="DEOXYRIBODIPYRIMIDINE PHOTO-LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10211">
        <property type="entry name" value="DEOXYRIBODIPYRIMIDINE PHOTOLYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="Cryptochrome/photolyase FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="Cryptochrome/photolyase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01084">
        <property type="entry name" value="DNA_PHOTOLYASES_2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0274">FAD</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="13">
        <location>
            <begin position="301"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG97914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="776" mass="92327" checksum="26588A96BEA9A9BA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZU3</accession>
    <name>A0A1J1GZU3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, putative</fullName>
            <ecNumber evidence="7">2.7.1.148</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">IspE</name>
        <name evidence="7" type="ORF">PGAL8A_00024300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.148" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530608.1">
        <property type="nucleotide sequence ID" value="XM_028674235.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZU3"/>
    <dbReference type="GeneID" id="39728766"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00024300"/>
    <dbReference type="OMA" id="RKETHNE"/>
    <dbReference type="OrthoDB" id="3191556at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050515">
        <property type="term" value="F:4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="entry name" value="GHMP kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00061">
        <property type="entry name" value="IspE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004424">
        <property type="entry name" value="IspE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43527">
        <property type="entry name" value="4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43527:SF2">
        <property type="entry name" value="4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="GHMP Kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 7" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012339720" evidence="5">
        <location>
            <begin position="26"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP kinase N-terminal" evidence="6">
        <location>
            <begin position="223"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="497" mass="58634" checksum="DB24A4CB3AD6CF85" modified="2017-02-15" version="1">MKFSININTFVFLYINLVFFNMAHKNVFNKDSKVIKSKMKNSKRKISNIYFITQNKKINNKLTLRKNRKSNYLNQNTNYEVKENINLDIDQNINNNEAFYKKENVLCNKKMKLILQVLNRTKWFDFKFFSPAKINLFLRLKEKKDGYNEISTLMHSINLGDDLFVTILNKENQKKLRNLLHQCSSGDFLTIKKSKKCKIKHKNTYTKKEKDLYYNNYPLNDDNIIIKILKKYREELNINDDIKFLVHANKRIPIFGGLGGGSSDGATIFYFLEKYFYKYLKLNTLKSDFLKKIGSDISFFDSSGFAYCTGKGNDIIDLKNVFSDIIKDRIYLFQFNEGLSSKLVYENVDYNKIIQYNPVDLLENIINSNNNITEIIKEKEKKYMKSFVKIESKDLHKIFINDLEHSAFFLAKKLKEIKKILVDQNIFQVVTMSGSGSTLFAIPKNNINLDLEKIQIKNLIEHIQEKLNVKIKIYLCNILRKNEKIWYKPKKIAEVIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZY1</accession>
    <name>A0A1J1GZY1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00047600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530838.1">
        <property type="nucleotide sequence ID" value="XM_028674491.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729001"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00047600"/>
    <dbReference type="OMA" id="FHCFSAG"/>
    <dbReference type="OrthoDB" id="392903at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG98041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1289" mass="158202" checksum="5146BDF3CD8D37A2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H020</accession>
    <name>A0A1J1H020_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Heat shock protein 86 family protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00048700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NKAP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530849.1">
        <property type="nucleotide sequence ID" value="XM_028674503.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H020"/>
    <dbReference type="GeneID" id="39729012"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00048700"/>
    <dbReference type="OMA" id="NNDNEKC"/>
    <dbReference type="OrthoDB" id="273141at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040466">
        <property type="entry name" value="NKAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009269">
        <property type="entry name" value="NKAP_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13087">
        <property type="entry name" value="NF-KAPPA B ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13087:SF0">
        <property type="entry name" value="NFKB ACTIVATING PROTEIN LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06047">
        <property type="entry name" value="Nkap_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="NF-kappa-B-activating protein C-terminal" evidence="3">
        <location>
            <begin position="725"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="131"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="399"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="39"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="81"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="144"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="166"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="212"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="401"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="411"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="482"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="504"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="547"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="567"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="586"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="596"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG98052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="841" mass="99900" checksum="AD62B02C070024DD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H028</accession>
    <name>A0A1J1H028_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">GTPase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00061300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530973.1">
        <property type="nucleotide sequence ID" value="XM_028674640.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H028"/>
    <dbReference type="GeneID" id="39729138"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00061300"/>
    <dbReference type="OrthoDB" id="269151at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45782">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45782:SF4">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012091313" evidence="5">
        <location>
            <begin position="18"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="domain" description="G" evidence="6">
        <location>
            <begin position="528"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="194"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="91"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="195"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG98176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="761" mass="91010" checksum="EB0757C79D7DF219" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H088</accession>
    <name>A0A1J1H088_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Oocyst capsule protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00059600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530958.1">
        <property type="nucleotide sequence ID" value="XM_028674624.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729121"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00059600"/>
    <dbReference type="OMA" id="ECYMWYY"/>
    <dbReference type="OrthoDB" id="380437at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012475674" description="Oocyst capsule protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="1989"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="525"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1989" mass="241816" checksum="A5ADCDCA5AE34670" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0F1</accession>
    <name>A0A1J1H0F1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">E3 ubiquitin-protein ligase CHIP</fullName>
            <ecNumber evidence="2">2.3.2.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">RING-type E3 ubiquitin transferase CHIP</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00047800</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530840.1">
        <property type="nucleotide sequence ID" value="XM_028674493.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0F1"/>
    <dbReference type="GeneID" id="39729003"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00047800"/>
    <dbReference type="OMA" id="NTNNCET"/>
    <dbReference type="OrthoDB" id="273087at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071218">
        <property type="term" value="P:cellular response to misfolded protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045862">
        <property type="term" value="P:positive regulation of proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16654">
        <property type="entry name" value="RING-Ubox_CHIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045202">
        <property type="entry name" value="CHIP_RING-Ubox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46803">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE CHIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46803:SF2">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE CHIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04564">
        <property type="entry name" value="U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 9" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="repeat" description="TPR" evidence="9">
        <location>
            <begin position="465"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="U-box" evidence="11">
        <location>
            <begin position="644"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="131"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="309"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="427"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="143"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="204"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="244"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="256"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="309"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="334"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="348"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG98043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="721" mass="83492" checksum="093788340758FA12" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0I5</accession>
    <name>A0A1J1H0I5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Eukaryotic translation initiation factor 3 subunit B</fullName>
            <shortName evidence="6 7">eIF3b</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Eukaryotic translation initiation factor 3 subunit 9</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00039200</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="6">RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 7">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the eIF-3 subunit B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530754.1">
        <property type="nucleotide sequence ID" value="XM_028674396.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0I5"/>
    <dbReference type="GeneID" id="39728916"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00039200"/>
    <dbReference type="OMA" id="HLFWAPR"/>
    <dbReference type="OrthoDB" id="10250414at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12278">
        <property type="entry name" value="RRM_eIF3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03001">
        <property type="entry name" value="eIF3b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011400">
        <property type="entry name" value="EIF3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034363">
        <property type="entry name" value="eIF3B_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013979">
        <property type="entry name" value="TIF_beta_prop-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14068">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 EIF3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14068:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08662">
        <property type="entry name" value="eIF2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036424">
        <property type="entry name" value="eIF3b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5 6 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6 7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="49"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR036424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG97955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="716" mass="83654" checksum="59E95E038F10AFB2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0N1</accession>
    <name>A0A1J1H0N1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Erythrocyte membrane-associated antigen, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00043600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA2/NAM7 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530802.1">
        <property type="nucleotide sequence ID" value="XM_028674451.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728961"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00043600"/>
    <dbReference type="OMA" id="DSWHRQN"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001247">
        <property type="entry name" value="Erythrocyte membrane-associated antigen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001232">
        <property type="entry name" value="Erythrocyte membrane-associated antigen, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050534">
        <property type="entry name" value="Coronavir_polyprotein_1ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43788">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43788:SF16">
        <property type="entry name" value="HELICASE WITH ZINC FINGER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="1554"/>
            <end position="1774"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG98005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2064" mass="239042" checksum="28BF1CE780C97E70" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1X5</accession>
    <name>A0A1J1H1X5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MORN repeat-containing protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">MORN1</name>
        <name evidence="2" type="ORF">PGAL8A_00490500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530128.1">
        <property type="nucleotide sequence ID" value="XM_028673702.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1X5"/>
    <dbReference type="GeneID" id="39733438"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00490500"/>
    <dbReference type="OMA" id="DRHEGMY"/>
    <dbReference type="OrthoDB" id="270720at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.110.10:FF:000002">
        <property type="entry name" value="Phosphatidylinositol 4-phosphate 5-kinase 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43215">
        <property type="entry name" value="RADIAL SPOKE HEAD 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43215:SF14">
        <property type="entry name" value="RADIAL SPOKE HEAD 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="364" mass="41117" checksum="B9F6F68B5156317A" modified="2017-02-15" version="1">MSEDTHAYHGNIKDGLFHGYGVLIYSKNEKYEGDFVYGKREGKGKFTYADGATYEGEWIDDKIHGKGIAKFISGNVYEGEWENGKINGFGILSYNNGDIYEGEWLDGKMHGRGTYTYEDGDVYIGEWKNDKRHGKGCVKYKGNENKIAETYEGDWVEGKMQGKGIYTFADGGIYEGDWIDGKMEGKGIYKYLNGNVYEGEWSNDMKNGYGVLTYVNGEKYEGYWKNDKVHGKGTLTYSKGDKYIGGWKYAKKCGEGELIYASGDRFKGEWKNDQANGFGILLYANGNKYEGEWIDDQRHGYGTFSCKEDGSVYSGYFAYNRREGKGTLTFVNGNILEGIWNLGVLTKVTNFKLSPSSPWNDADL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H241</accession>
    <name>A0A1J1H241_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SNARE protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00516800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SNAP-25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530396.1">
        <property type="nucleotide sequence ID" value="XM_028674000.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H241"/>
    <dbReference type="GeneID" id="39733701"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00516800"/>
    <dbReference type="OMA" id="WWKNINS"/>
    <dbReference type="OrthoDB" id="19261at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19305">
        <property type="entry name" value="SYNAPTOSOMAL ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19305:SF9">
        <property type="entry name" value="SYNAPTOSOMAL-ASSOCIATED PROTEIN 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="3">
        <location>
            <begin position="16"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="3">
        <location>
            <begin position="142"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="26"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="145"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="207" mass="24801" checksum="7E4841B32FCB1674" modified="2017-02-15" version="1">MELSHKKSTYDRKKITEIEKKCEESLNEILRSANEAKEISKKAEEELEHQTEQIKHIHKETEDIQENLKQSQYHLHGIKYWWKNINSFLGFETYKNNENKKTNNKLNETKRSIKLNDNNKNVKNHDIYKNSMKIENTSKRNETFEEKYESNLNSLSAVLDELHTRALIMGNTINEQNKMLNEVNEKMECNIEKIRDQQKLMKEIMKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2P3</accession>
    <name>A0A1J1H2P3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00533300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530556.1">
        <property type="nucleotide sequence ID" value="XM_028674177.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2P3"/>
    <dbReference type="GeneID" id="39733866"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00533300"/>
    <dbReference type="OMA" id="NIMFTIL"/>
    <dbReference type="OrthoDB" id="378086at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="13"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="70"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="331"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="524" mass="62472" checksum="01E757E33F624026" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3B2</accession>
    <name>A0A1J1H3B2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00026600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530631.1">
        <property type="nucleotide sequence ID" value="XM_028674260.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3B2"/>
    <dbReference type="GeneID" id="39728789"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00026600"/>
    <dbReference type="OMA" id="AFRKHES"/>
    <dbReference type="OrthoDB" id="360581at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="674"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="674"/>
            <end position="684"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="693" mass="84308" checksum="EE355BCF8F412B69" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3Z5</accession>
    <name>A0A1J1H3Z5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00050900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530871.1">
        <property type="nucleotide sequence ID" value="XM_028674527.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3Z5"/>
    <dbReference type="GeneID" id="39729034"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00050900"/>
    <dbReference type="OMA" id="EWSEQID"/>
    <dbReference type="OrthoDB" id="371948at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="362"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="388" mass="45753" checksum="8AC738878C769786" modified="2017-02-15" version="1">MIEFDEIFEFLREVENTCDNFNEEEEENEKIILFINELKSYINDFSNSLKEKINKSSGTTELDLLEKINNKKKSLEKIILKEKNNFNNIKKKGILYNNDNISNLSNDINNNCMNYDNLNNDTINNYMTNNNSNNVDNTKNIEDNNSNLTIKNVEDVKNHFDEVNYNSLKNCNENFSYNNDINNIIIKTKKNKEKEETKKSISFNLNNINMSNLNGYNNIKGVKIEEEITSENSKKTLLTDEEKIYTTNLENCQILKDDIIKEWSNHIDEYDNLLYEYTYEYKKNHVRKKMEKKNKINFFSENIDEELCLLAQEMKENVLTYREIIIEDNKTLEKAASKQLQNIDALEDVNKKTKKMNEGKNISFFLSLLIIAISILLFILTFFVIVFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2012-05-16" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>H7CDX5</accession>
    <name>H7CDX5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Apicoplast ribosomal protein L14, putative</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Large subunit ribosomal protein 14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpl14</name>
        <name evidence="5" type="synonym">RPL14</name>
        <name evidence="5" type="ORF">PGAL8A_API01900</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <geneLocation type="apicoplast" evidence="4"/>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Mol. Biol. Evol." volume="29" first="2095" last="2099">
            <title>The Plasmodium Apicoplast Genome: Conserved Structure and Close Relationship of P. ovale to Rodent Malaria Parasites.</title>
            <authorList>
                <person name="Arisue N."/>
                <person name="Hashimoto T."/>
                <person name="Mitsui H."/>
                <person name="Palacpac N.M.Q."/>
                <person name="Kaneko A."/>
                <person name="Kawai S."/>
                <person name="Hasegawa M."/>
                <person name="Tanabe K."/>
                <person name="Horii T."/>
            </authorList>
            <dbReference type="PubMed" id="22396524"/>
            <dbReference type="DOI" id="10.1093/molbev/mss082"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">A8</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL14 family.</text>
    </comment>
    <dbReference type="EMBL" id="AB649424">
        <property type="protein sequence ID" value="BAL70745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LN835293">
        <property type="protein sequence ID" value="CRG98234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009325461.1">
        <property type="nucleotide sequence ID" value="NC_031963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="H7CDX5"/>
    <dbReference type="GeneID" id="30315807"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_API01900"/>
    <dbReference type="OMA" id="YKKSDKC"/>
    <dbReference type="OrthoDB" id="274765at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Apicoplast API"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00337">
        <property type="entry name" value="Ribosomal_uL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.150.20">
        <property type="entry name" value="Ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01367">
        <property type="entry name" value="Ribosomal_uL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000218">
        <property type="entry name" value="Ribosomal_uL14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036853">
        <property type="entry name" value="Ribosomal_uL14_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00238">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01374">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50193">
        <property type="entry name" value="Ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0933">Apicoplast</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAL70745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG98234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="120" mass="14126" checksum="50DB858254217C11" modified="2012-05-16" version="1">MIYLNSLLDVIDNSGIFKFKYINVLNKCKKPKYGDIIIGVVYKLYNNNLYKKSDKCKGILVQQKLFLNLKIYYSIKFNKNAVIILNNNLISVGTKSNNYILKYIKYNKNINIKKLKIKYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2012-05-16" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>H7CDY3</accession>
    <name>H7CDY3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Apicoplast ribosomal protein S7, putative</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Small subunit ribosomal protein 7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rps7</name>
        <name evidence="5" type="synonym">RPS7</name>
        <name evidence="5" type="ORF">PGAL8A_API02700</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <geneLocation type="apicoplast" evidence="4"/>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Mol. Biol. Evol." volume="29" first="2095" last="2099">
            <title>The Plasmodium Apicoplast Genome: Conserved Structure and Close Relationship of P. ovale to Rodent Malaria Parasites.</title>
            <authorList>
                <person name="Arisue N."/>
                <person name="Hashimoto T."/>
                <person name="Mitsui H."/>
                <person name="Palacpac N.M.Q."/>
                <person name="Kaneko A."/>
                <person name="Kawai S."/>
                <person name="Hasegawa M."/>
                <person name="Tanabe K."/>
                <person name="Horii T."/>
            </authorList>
            <dbReference type="PubMed" id="22396524"/>
            <dbReference type="DOI" id="10.1093/molbev/mss082"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">A8</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <dbReference type="EMBL" id="AB649424">
        <property type="protein sequence ID" value="BAL70753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LN835293">
        <property type="protein sequence ID" value="CRG98242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009325469.1">
        <property type="nucleotide sequence ID" value="NC_031963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="H7CDY3"/>
    <dbReference type="GeneID" id="30315806"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_API02700"/>
    <dbReference type="OMA" id="IICKYLI"/>
    <dbReference type="OrthoDB" id="372959at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Apicoplast API"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="entry name" value="Ribosomal protein S7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_uS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_uS7_dom_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002122">
        <property type="entry name" value="RPS7p_RPS7a_RPS5e_RPS7o"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="Ribosomal protein S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0933">Apicoplast</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAL70753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG98242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="141" mass="17030" checksum="48A6D5D24F4337D2" modified="2012-05-16" version="1">MIIFKYFVKIYLKKGNINKSIKLLIYILYLLKKITKKSGIFIFNKAIKNLLLPFSFLKIKINTIKYYIPIIISYEQSIFNVYKLFIKIIKNKNIMLYKIICKYIILSYNKEGDLYKMKLNLIKQFISNRVYIYLLNKSKII</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKY7</accession>
    <name>A0A1J1GKY7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glutamate dehydrogenase, putative</fullName>
            <ecNumber evidence="6">1.4.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">GDH3</name>
        <name evidence="6" type="ORF">PGAL8A_00078200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.2" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525902.1">
        <property type="nucleotide sequence ID" value="XM_028670266.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKY7"/>
    <dbReference type="GeneID" id="39729307"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00078200"/>
    <dbReference type="OrthoDB" id="184415at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004352">
        <property type="term" value="F:glutamate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004069">
        <property type="term" value="F:L-aspartate:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006538">
        <property type="term" value="P:L-glutamate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056365">
        <property type="entry name" value="NAD-GDH_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028971">
        <property type="entry name" value="NAD-GDH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055480">
        <property type="entry name" value="NAD-GDH_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11606">
        <property type="entry name" value="GLUTAMATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11606:SF24">
        <property type="entry name" value="NAD-SPECIFIC GLUTAMATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05088">
        <property type="entry name" value="Bac_GDH_CD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23147">
        <property type="entry name" value="GDH2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23152">
        <property type="entry name" value="GDH_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal" evidence="5">
        <location>
            <begin position="734"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="631"/>
            <end position="658"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1170" mass="135974" checksum="8CD3A60B0A0A7365" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL23</accession>
    <name>A0A1J1GL23_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA repair protein RAD54, putative</fullName>
            <ecNumber evidence="6">3.6.4.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RAD54</name>
        <name evidence="6" type="ORF">PGAL8A_00079600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525916.1">
        <property type="nucleotide sequence ID" value="XM_028670422.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL23"/>
    <dbReference type="GeneID" id="39729321"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00079600"/>
    <dbReference type="OMA" id="CADDENA"/>
    <dbReference type="OrthoDB" id="413460at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015616">
        <property type="term" value="F:DNA translocase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045003">
        <property type="term" value="P:double-strand break repair via synthesis-dependent strand annealing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18004">
        <property type="entry name" value="DEXHc_RAD54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000021">
        <property type="entry name" value="DNA repair and recombination protein RAD54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.850">
        <property type="entry name" value="SWI2/SNF2 ATPases, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050496">
        <property type="entry name" value="SNF2_RAD54_helicase_repair"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629:SF7">
        <property type="entry name" value="DNA EXCISION REPAIR PROTEIN ERCC-6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45629">
        <property type="entry name" value="SNF2/RAD54 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="4">
        <location>
            <begin position="150"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="5">
        <location>
            <begin position="533"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="828"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="455"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="837"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="895"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="953"/>
            <end position="962"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1031" mass="120307" checksum="AB24DBB1EB0AF13E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLA7</accession>
    <name>A0A1J1GLA7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00081100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525929.1">
        <property type="nucleotide sequence ID" value="XM_028670566.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLA7"/>
    <dbReference type="GeneID" id="39729335"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00081100"/>
    <dbReference type="OMA" id="HNKCLRW"/>
    <dbReference type="OrthoDB" id="446723at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277">
        <property type="entry name" value="ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277:SF81">
        <property type="entry name" value="PROTEIN ABHD13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="48"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="244" mass="28262" checksum="ABE171C13B4747EE" modified="2017-02-15" version="1">MGNFLNKIIFNAPSEGSFENFDLDLIYIETENHEKVAAHFINRNAPLTILFCHGNSENIYMLYDYFYETSRIWDVNIFLYDYLGYGKSTGIASEENMYLSGNAVYDYMVNNLNIKPDSIVIYGKSIGSCAAVELASNRIVKGIILQSAILSLLNICFKTRFIFPFDSFCNINKIKNIPCYIFFIHGTEDKIVPFYHGISLYEKCKLKVHPYWVIDGKHNDIEIIENEKFNEHIKSFLNFLINLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLD8</accession>
    <name>A0A1J1GLD8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00092600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526044.1">
        <property type="nucleotide sequence ID" value="XM_028671843.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLD8"/>
    <dbReference type="GeneID" id="39729450"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00092600"/>
    <dbReference type="OrthoDB" id="370336at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="248" mass="30544" checksum="7B18EC804545C628" modified="2017-02-15" version="1">MNFHIYFFKTFARFLCIKNETPYFFKNGSRILINEKKSYNINYVEKENNKYTLINNIHYIKESDFFNRLIKIYIDIIFNFSKYPLHVQCLHIFCKKILKEKIENVKSSLEHKKVLYNSDNIKFENLNEYLVNLNKESIEKKESEEYFNKVFEKVKKFYYYKNVLYALFTLEHNKIIFNYTENLLIKDLQNCLINSTLNNSKDIYRFIKKNGQDNIYIYIIEFSDNLYILKKRYNFIKYLFYNNMQNKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLP3</accession>
    <name>A0A1J1GLP3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="7">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00084500</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="7">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525963.1">
        <property type="nucleotide sequence ID" value="XM_028670943.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLP3"/>
    <dbReference type="GeneID" id="39729369"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00084500"/>
    <dbReference type="OMA" id="QYDPPQQ"/>
    <dbReference type="OrthoDB" id="422663at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025313">
        <property type="entry name" value="SPB4-like_CTE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13959">
        <property type="entry name" value="CTE_SPB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01178">
        <property type="entry name" value="DUF4217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="182"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="477"/>
            <end position="659"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG93141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="791" mass="93004" checksum="D2F100692F1A8003" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLP8</accession>
    <name>A0A1J1GLP8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">mTERF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00097400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the mTERF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526090.1">
        <property type="nucleotide sequence ID" value="XM_028672355.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLP8"/>
    <dbReference type="GeneID" id="39729498"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00097400"/>
    <dbReference type="OrthoDB" id="637682at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.70.10">
        <property type="entry name" value="Transcription termination factor 3, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003690">
        <property type="entry name" value="MTERF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038538">
        <property type="entry name" value="MTERF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02536">
        <property type="entry name" value="mTERF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00733">
        <property type="entry name" value="Mterf"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="325"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="329"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="343"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="366"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="378"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="679" mass="82634" checksum="9CC217C520327FA0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLV7</accession>
    <name>A0A1J1GLV7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Perforin like protein 5, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PLP5</name>
        <name evidence="3" type="ORF">PGAL8A_00112200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526238.1">
        <property type="nucleotide sequence ID" value="XM_028673999.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLV7"/>
    <dbReference type="GeneID" id="39729647"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00112200"/>
    <dbReference type="OrthoDB" id="369671at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020864">
        <property type="entry name" value="MACPF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01823">
        <property type="entry name" value="MACPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51412">
        <property type="entry name" value="MACPF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012814262" evidence="1">
        <location>
            <begin position="24"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="domain" description="MACPF" evidence="2">
        <location>
            <begin position="32"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="629" mass="73105" checksum="20219672AD56632F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM38</accession>
    <name>A0A1J1GM38_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Protein disulfide-isomerase</fullName>
            <ecNumber evidence="4 13">5.3.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PGAL8A_00121100</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Catalyzes the rearrangement of -S-S- bonds in proteins.</text>
            <dbReference type="EC" id="5.3.4.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the protein disulfide isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.4.1" evidence="4 13"/>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526326.1">
        <property type="nucleotide sequence ID" value="XM_028674724.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM38"/>
    <dbReference type="GeneID" id="39729736"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00121100"/>
    <dbReference type="OMA" id="QLANKFE"/>
    <dbReference type="OrthoDB" id="72053at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034976">
        <property type="term" value="P:response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02995">
        <property type="entry name" value="PDI_a_PDI_a'_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02982">
        <property type="entry name" value="PDI_b'_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000045">
        <property type="entry name" value="Disulfide-isomerase A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000023">
        <property type="entry name" value="Protein disulfide-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005788">
        <property type="entry name" value="PDI_thioredoxin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005792">
        <property type="entry name" value="Prot_disulphide_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01130">
        <property type="entry name" value="ER_PDI_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01126">
        <property type="entry name" value="pdi_dom"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18929">
        <property type="entry name" value="PROTEIN DISULFIDE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18929:SF132">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13848">
        <property type="entry name" value="Thioredoxin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 13 15" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10 11" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 13" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011832512" description="Protein disulfide-isomerase" evidence="13">
        <location>
            <begin position="19"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="14">
        <location>
            <begin position="11"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="14">
        <location>
            <begin position="337"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="11">
        <location>
            <begin position="59"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="11">
        <location>
            <begin position="383"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR605792-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG93504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="482" mass="55225" checksum="5CEF34040323655C" modified="2017-02-15" version="1">MNAKYISFFLLLIPFVFQNFIRSHEDLFNDLVTEIHDGELEKFITKNNIVLVMFYAPWCGHCKRLIPEYNEAANILSDKKSEIKLASVDATTENALAQEYGITGYPTLILFNKKRRVNYGGGRTAQLIVDWLLQMTGPVFTEIEGNIEDVLSEKNISVAFYLEYTSEDNELYKKFNEIGDKNRELAKFFVKKNDKHNKLYCHRKDENKVEYDEKTSLDEFINTESFPLFGAINTENYRFYAESSKELVWVCATNEQYNEIKEEVRLAAAELRSKTHFVLLNVPEYADHAKASLGLNEFPGLAFQSSEGRFLLPNAKESLRNHKEIIKFFKDVEEGKIEKSLKSEPIPEEDKDAPVKVVVGNSFVDVVLKSGKDVLIEIYAPWCGHCKKLQPIYEELGKHLKKYDSLIIAKMDGTLNETPIKDFEWSGFPTIFFVKAGSKVPLPYEGERTLKGFVDFLNKHATNTPISIEGVSQDTDGSEEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMB9</accession>
    <name>A0A1J1GMB9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">V-type proton ATPase subunit a</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00109400</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the V-ATPase 116 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526211.1">
        <property type="nucleotide sequence ID" value="XM_028673699.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMB9"/>
    <dbReference type="GeneID" id="39729620"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00109400"/>
    <dbReference type="OMA" id="TYVQLYI"/>
    <dbReference type="OrthoDB" id="10264220at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000220">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051117">
        <property type="term" value="F:ATPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002490">
        <property type="entry name" value="V-ATPase_116kDa_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026028">
        <property type="entry name" value="V-type_ATPase_116kDa_su_euka"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11629:SF63">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11629">
        <property type="entry name" value="VACUOLAR PROTON ATPASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01496">
        <property type="entry name" value="V_ATPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001293">
        <property type="entry name" value="ATP6V0A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="440"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="486"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="572"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="602"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="670"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="839"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="283"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG93389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="906" mass="106714" checksum="04C4B7A824482008" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GME1</accession>
    <name>A0A1J1GME1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Surface-associated interspersed protein (SURFIN)</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00130300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526420.1">
        <property type="nucleotide sequence ID" value="XM_028674828.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GME1"/>
    <dbReference type="GeneID" id="39729828"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00130300"/>
    <dbReference type="OrthoDB" id="373054at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="854" mass="100095" checksum="1EE65A59A8E5160A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMI3</accession>
    <name>A0A1J1GMI3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">WD repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00135100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526468.1">
        <property type="nucleotide sequence ID" value="XM_028674881.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729876"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00135100"/>
    <dbReference type="OMA" id="NNIAHYE"/>
    <dbReference type="OrthoDB" id="340226at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031087">
        <property type="term" value="P:deadenylation-independent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045152">
        <property type="entry name" value="EDC4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15598">
        <property type="entry name" value="ENHANCER OF MRNA-DECAPPING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15598:SF5">
        <property type="entry name" value="ENHANCER OF MRNA-DECAPPING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="946"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1510"/>
            <end position="1535"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1087"/>
            <end position="1125"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1237"/>
            <end position="1271"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1458"/>
            <end position="1485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="952"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="973"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1517"/>
            <end position="1535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1779" mass="208299" checksum="6CF03E4D1FDAA953" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMN4</accession>
    <name>A0A1J1GMN4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Coiled-coil domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00122400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCDC124 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526339.1">
        <property type="nucleotide sequence ID" value="XM_028674738.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMN4"/>
    <dbReference type="GeneID" id="39729749"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00122400"/>
    <dbReference type="OMA" id="PKANYTK"/>
    <dbReference type="OrthoDB" id="76412at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010422">
        <property type="entry name" value="Ccdc124/Oxs1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054414">
        <property type="entry name" value="Ccdc124/Oxs1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21680">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21680:SF0">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06244">
        <property type="entry name" value="Ccdc124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Coiled-coil" evidence="4">
        <location>
            <begin position="130"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="42"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="42"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="216" mass="25902" checksum="6DCC1D6E1F88C867" modified="2017-02-15" version="1">MPQWGAGNSRAIEARLRKKLEKDRKQKEIEEKKLEEYWRDDDKKVQAKIQRKTEAENKRQQKLDRKKELRALYGEEEKSMKSNKESKTTNTKVSQAEILQRLIEEKKKELEEEKKKKNNINVHEMELEENINHIQRNEMNDYDEYINATGIDNAISALENISFDKTKKVKVAYKKFEEENLPIVKEEYKGLKLSQYKQILWKQFKKSVDNPLNQKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN12</accession>
    <name>A0A1J1GN12_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="4">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PGAL8A_00155800</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526670.1">
        <property type="nucleotide sequence ID" value="XM_028675105.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN12"/>
    <dbReference type="GeneID" id="39730082"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00155800"/>
    <dbReference type="OMA" id="NEFKYEK"/>
    <dbReference type="OrthoDB" id="10254945at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16745">
        <property type="entry name" value="RING-HC_AtRMA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045103">
        <property type="entry name" value="RNF5/RNF185-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12313">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="500"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="14">
        <location>
            <begin position="366"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="265"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="424"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="265"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="331"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="428"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG93849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="521" mass="62033" checksum="520DBCF62607F0AD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN67</accession>
    <name>A0A1J1GN67_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Anaphase promoting complex subunit, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00153000</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526642.1">
        <property type="nucleotide sequence ID" value="XM_028675074.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN67"/>
    <dbReference type="GeneID" id="39730054"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00153000"/>
    <dbReference type="OMA" id="QWRWDTG"/>
    <dbReference type="OrthoDB" id="1681166at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097602">
        <property type="term" value="F:cullin family protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000552">
        <property type="entry name" value="Anaphase promoting complex subunit, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051031">
        <property type="entry name" value="RING-box_E3_Ubiquitin_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024766">
        <property type="entry name" value="Znf_RING_H2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11210">
        <property type="entry name" value="RING BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12678">
        <property type="entry name" value="zf-rbx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="11">
        <location>
            <begin position="26"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG93821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="89" mass="10196" checksum="FB03F7AEC0E7F548" modified="2017-02-15" version="1">MPKVTVKKIHAVAKWKWLGTSTDSVCAICNNSLENTCTNCIRPGDNCPPAFGKCGHHFHLHCMEKWIKQNKLTCPCCRADWYYEIQNLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNJ5</accession>
    <name>A0A1J1GNJ5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transportin, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00156200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526675.1">
        <property type="nucleotide sequence ID" value="XM_028675110.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNJ5"/>
    <dbReference type="GeneID" id="39730087"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00156200"/>
    <dbReference type="OMA" id="AQEGAMS"/>
    <dbReference type="OrthoDB" id="951172at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040122">
        <property type="entry name" value="Importin_beta"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10527">
        <property type="entry name" value="IMPORTIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13513">
        <property type="entry name" value="HEAT_EZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="7">
        <location>
            <begin position="43"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="411"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1070" mass="124116" checksum="D7468D099F47758F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP31</accession>
    <name>A0A1J1GP31_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00393000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527047.1">
        <property type="nucleotide sequence ID" value="XM_028670279.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP31"/>
    <dbReference type="GeneID" id="39732460"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00393000"/>
    <dbReference type="OrthoDB" id="419333at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018881">
        <property type="entry name" value="C2orf69_mit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31296:SF1">
        <property type="entry name" value="MITOCHONDRIAL PROTEIN C2ORF69"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31296">
        <property type="entry name" value="UPF0565 PROTEIN C2ORF69"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10561">
        <property type="entry name" value="C2orf69"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="410" mass="48239" checksum="762C7EDC64A32ACA" modified="2017-02-15" version="1">MPVCFCVYNVCGYNEKYNTILYREPILINKDYDSKYIIFFPGDYSSFFYNSIYTSFKLESKYECTDYCFSYEALFWVISHKYLYDHIIFIKPCTFYNYYATFSNFLPSPEIYSYENTGNIIERNSKENNKTTTNNNNMTATSAKHLLSLLISLNKKLTENKKKYINSNSMNNADNLRNTTNGDNSDTNETNSSSNDNFYKNVTKDKTSMEKKFVNDNFNNEYYSIYLKEKIKKKLVLIGFSKGCTVLISLLREAYKIDVFWSIVDSIFFLDPGFNKNTFNSNIESYSLEKISEYNLKIYIHSTLRQIIDESGSCIHKQLLNFINSLKKFNICVSSYLHYTNVQNSIKPLSLHFEILVDFFQDISTDLHTHPLLLNSHEKTEIKLCNNKKCKENFLFESWRNSSSFNDQIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPH2</accession>
    <name>A0A1J1GPH2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Retrotransposon</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PGAL8A_00410600</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527220.1">
        <property type="nucleotide sequence ID" value="XM_028670471.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732636"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00410600"/>
    <dbReference type="OMA" id="DICTIST"/>
    <dbReference type="OrthoDB" id="2013610at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09274">
        <property type="entry name" value="RNase_HI_RT_Ty3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01647">
        <property type="entry name" value="RT_LTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.70:FF:000001">
        <property type="entry name" value="Retrovirus-related Pol polyprotein from transposon gypsy-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.270:FF:000020">
        <property type="entry name" value="Transposon Tf2-6 polyprotein-like Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.10.10">
        <property type="entry name" value="HIV Type 1 Reverse Transcriptase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041588">
        <property type="entry name" value="Integrase_H2C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050951">
        <property type="entry name" value="Retrovirus_Pol_polyprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041577">
        <property type="entry name" value="RT_RNaseH_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984">
        <property type="entry name" value="PROTEIN CBG26694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37984:SF5">
        <property type="entry name" value="PROTEIN NYNRIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17921">
        <property type="entry name" value="Integrase_H2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17919">
        <property type="entry name" value="RT_RNaseH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="11">
        <location>
            <begin position="240"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="Reverse transcriptase" evidence="12">
        <location>
            <begin position="604"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="domain" description="Integrase catalytic" evidence="13">
        <location>
            <begin position="1131"/>
            <end position="1293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="328"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="328"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG94399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1485" mass="173848" checksum="993107719B782201" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPT7</accession>
    <name>A0A1J1GPT7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00191300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000028">
        <property type="protein sequence ID" value="CRG94516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527332.1">
        <property type="nucleotide sequence ID" value="XM_028670595.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPT7"/>
    <dbReference type="GeneID" id="39730438"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00191300"/>
    <dbReference type="OMA" id="DKERTIM"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="435"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="497"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="455"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="506"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="539"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="557"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="572" mass="69183" checksum="5E1161E75BAB9EA6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ56</accession>
    <name>A0A1J1GQ56_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00182800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527257.1">
        <property type="nucleotide sequence ID" value="XM_028670512.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ56"/>
    <dbReference type="GeneID" id="39730355"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00182800"/>
    <dbReference type="OMA" id="RRMQVIY"/>
    <dbReference type="OrthoDB" id="2017782at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="905"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="183"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="701"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="762"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1039"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="183"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="708"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="724"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="763"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="777"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="797"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1045"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1065"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1075"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1088"/>
            <end position="1109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1119"/>
            <end position="1138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1265" mass="150209" checksum="43D8F28C7FC700A8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ66</accession>
    <name>A0A1J1GQ66_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00195500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527375.1">
        <property type="nucleotide sequence ID" value="XM_028670642.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ66"/>
    <dbReference type="GeneID" id="39730482"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00195500"/>
    <dbReference type="OMA" id="IDYNEEP"/>
    <dbReference type="OrthoDB" id="390250at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042776">
        <property type="entry name" value="Ribosomal_mL53_fung"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28236">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN L44, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28236:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="159" mass="19284" checksum="C6A4E17005123D3D" modified="2017-02-15" version="1">MPKFNFFPKVNLLAYVKKIKIKYNPCSTYNDNCRKLIHHIEAKQKKNKFLNLEYTLELIDYNEEPLIEIEMQNSKVFKFNPENYNLLEIQRVINNDQQQRKIHKKKKKKKKKNFYNSKTSKENSISSLLICLFIDISKLLNDRLVNWIHSSLFIMLYEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQE8</accession>
    <name>A0A1J1GQE8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">U6 snRNA-associated Sm-like protein LSm8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 11" type="primary">LSM8</name>
        <name evidence="11" type="ORF">PGAL8A_00122600</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">LSm subunits form a heteromer with a doughnut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526341.1">
        <property type="nucleotide sequence ID" value="XM_028674740.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQE8"/>
    <dbReference type="GeneID" id="39729751"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00122600"/>
    <dbReference type="OMA" id="TLESYMN"/>
    <dbReference type="OrthoDB" id="10263346at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01727">
        <property type="entry name" value="LSm8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000027">
        <property type="entry name" value="U6 snRNA-associated Sm-like protein LSm8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034103">
        <property type="entry name" value="Lsm8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044642">
        <property type="entry name" value="PTHR15588"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588">
        <property type="entry name" value="LSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588:SF9">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG93519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="95" mass="10892" checksum="64A558951375740F" modified="2017-02-15" version="1">MISINIESYLENEILVITNDSRIFTGKLKGFDQTTNIILSNCFERIYKDSLEKISLGLYIIRGDTVTLIGEIDEDVDKNILHDKIKPEILKPIVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQW2</accession>
    <name>A0A1J1GQW2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00224800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527666.1">
        <property type="nucleotide sequence ID" value="XM_028670966.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQW2"/>
    <dbReference type="GeneID" id="39730775"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00224800"/>
    <dbReference type="OMA" id="FNKFCDM"/>
    <dbReference type="OrthoDB" id="368332at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="88" mass="10960" checksum="4FD971F1D30347DA" modified="2017-02-15" version="1">MFNLSKSYLLRWNTSWTYKLKRYHMSPRWNVSKWLVKEEYKSQKFSKPFHLTKWGNFKTYQHQYSSNGAFNKFCDMKKLHEQNINLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR10</accession>
    <name>A0A1J1GR10_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00118000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526296.1">
        <property type="nucleotide sequence ID" value="XM_028674644.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR10"/>
    <dbReference type="GeneID" id="39729705"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00118000"/>
    <dbReference type="OrthoDB" id="378221at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="559"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="669"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="939" mass="113581" checksum="E65135712BBF8D44" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR78</accession>
    <name>A0A1J1GR78_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00216900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527587.1">
        <property type="nucleotide sequence ID" value="XM_028670879.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR78"/>
    <dbReference type="GeneID" id="39730696"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00216900"/>
    <dbReference type="OMA" id="FESIGVC"/>
    <dbReference type="OrthoDB" id="383952at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="35"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="475" mass="57223" checksum="09E4E8735E55F9C8" modified="2017-02-15" version="1">MNENNKKKSNNEEKIRSIDIYFDSEETNVPINYSKDKYELQKEKINKKISEKYDKKEFSILNSFQKELNDKNEYMKKKEIEKNPRQKKNYVEENINLNNEEFEIPIQRRNTKNDYYNNNFYKNIEHDKEYEDDKKLHLLDIFNYNDFPINLFGKKKKKEKNKEKKFVIEFLDSYNDEFVKKNIDNNLIFESIGVCKGVSFLYIGKNININCIGSKDDNAFYFYKMIPFNKIYSKDAINKILSKKKVVSKKEDIRQSDIKNINSNIDHKNYFLNYYNILKNYFFKDKKKKTLYNDLYLSPYEKNLKSSVCIGTHIYSKERAVKKCFGLLIEQNVYNIDQPHDDNTTVNKNLENLYFDFPYDKHQIIFKPIYYPYKNIKIINNSLKNYLKSIHFEKLSHLKDSQFYYNAKKNIFDFSKDLYLTTKNAIKYFDSPKDFIIQTTKRMQDINIQIKKICEKSLYIIHDSILKLSKASKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRC1</accession>
    <name>A0A1J1GRC1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Dihydrofolate synthase/folylpolyglutamate synthase, putative</fullName>
            <ecNumber evidence="8">6.3.2.12</ecNumber>
            <ecNumber evidence="8">6.3.2.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">DHFS-FPGS</name>
        <name evidence="8" type="ORF">PGAL8A_00236700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the folylpolyglutamate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.12" evidence="8"/>
    <dbReference type="EC" id="6.3.2.17" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527783.1">
        <property type="nucleotide sequence ID" value="XM_028671097.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRC1"/>
    <dbReference type="GeneID" id="39730895"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00236700"/>
    <dbReference type="OMA" id="KGTTCAK"/>
    <dbReference type="OrthoDB" id="5212574at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008841">
        <property type="term" value="F:dihydrofolate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004326">
        <property type="term" value="F:tetrahydrofolylpolyglutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1190.10:FF:000015">
        <property type="entry name" value="Dihydrofolate synthase/folylpolyglutamate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="entry name" value="Mur ligase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="entry name" value="Mur-like, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001645">
        <property type="entry name" value="Folylpolyglutamate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018109">
        <property type="entry name" value="Folylpolyglutamate_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01499">
        <property type="entry name" value="folC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136:SF0">
        <property type="entry name" value="DIHYDROFOLATE SYNTHETASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136">
        <property type="entry name" value="FOLYLPOLYGLUTAMATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="MurD-like peptide ligases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="MurD-like peptide ligases, peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01012">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur ligase central" evidence="7">
        <location>
            <begin position="47"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="471" mass="54280" checksum="40F3A3FADA97C995" modified="2017-02-15" version="1">MEEQIKTYSECLDKLYKTHSIKLGLDNSKKLSESFDNPCDKYKTIHIAGTNGKGSVCYKIYSCLKLKKYKVGLFSSPHIFSLRERIIVDDELINEEDLIFLVNKVINKIKKIDIKPSFFEIITMVAYLHFLNKEVDYAIIETGLGGRLDATNILSKPELIVITSIGYDHSHILGNELNLICNEKIGIFKKDTNVIIGPSVSIYKNVFEKAKELNCRITLVSPEPRGETYNEENSRIALEALKILNINVDNFLKSVIYIKPPLRLQYLAQEQIHHVKKKYTSNNLDNNFSLYPCAVILDVGHNETAIDRLCTDINYFHKGKLIRICISLTKPRNLNIFHPFIAHFPDTLKDVFYLPSINQRTYDFEEITDMINNDDQIDNKLKQLILDSSEKVRRWLQCNNKENIDGAENFDKLYKRGTIPLIVKNAFLECCKDNSILLIVGTFFMFDEVLNTFDIYSDIQDSVCMNEPSLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRD0</accession>
    <name>A0A1J1GRD0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sec14 domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00154900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526661.1">
        <property type="nucleotide sequence ID" value="XM_028675095.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRD0"/>
    <dbReference type="GeneID" id="39730073"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00154900"/>
    <dbReference type="OMA" id="KGVIYWH"/>
    <dbReference type="OrthoDB" id="7777654at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46818:SF1">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_125, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46818">
        <property type="entry name" value="DOMAIN-CONTAINING PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="3">
        <location>
            <begin position="114"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="670"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="329"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="679"/>
            <end position="690"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="841" mass="99381" checksum="A13C571397CE432D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRD8</accession>
    <name>A0A1J1GRD8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Myosin light chain, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00155700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526669.1">
        <property type="nucleotide sequence ID" value="XM_028675104.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRD8"/>
    <dbReference type="GeneID" id="39730081"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00155700"/>
    <dbReference type="OMA" id="VESAFCE"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="1">
        <location>
            <begin position="73"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="139" mass="16189" checksum="CAF04FF0538F4130" modified="2017-02-15" version="1">MEELIDEIELTSLFNKLSDGSKNINSENALEIIYKLGYVPSKEDIEEFVYVTNGSCTLSNIKKFCNKLRSSKYSTENLIDLFYFYDTKKTGKISKKMFKILFTTVGSKLSNKEIDIITSELCNDEEFIDYKEFLDKFFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRE5</accession>
    <name>A0A1J1GRE5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00156400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic/archaeal RNase P protein component 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526677.1">
        <property type="nucleotide sequence ID" value="XM_028675114.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRE5"/>
    <dbReference type="GeneID" id="39730089"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00156400"/>
    <dbReference type="OMA" id="MELNGAY"/>
    <dbReference type="OrthoDB" id="124041at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000172">
        <property type="term" value="C:ribonuclease MRP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030677">
        <property type="term" value="C:ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033204">
        <property type="term" value="F:ribonuclease P RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.210">
        <property type="entry name" value="Ribonuclease P/MRP, subunit p29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016848">
        <property type="entry name" value="RNase_P/MRP_Rpp29-subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036980">
        <property type="entry name" value="RNase_P/MRP_Rpp29_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023534">
        <property type="entry name" value="Rof/RNase_P-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002730">
        <property type="entry name" value="Rpp29/RNP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13348:SF0">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13348">
        <property type="entry name" value="RIBONUCLEASE P SUBUNIT P29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01868">
        <property type="entry name" value="RNase_P-MRP_p29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00538">
        <property type="entry name" value="POP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101744">
        <property type="entry name" value="Rof/RNase P subunit-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="313" mass="36766" checksum="FBAE859CF239E916" modified="2017-02-15" version="1">MEEDNINEINKKRKTDNKKYLNYYLHSKRLYTNYENNPPFINSQFNNQIKSNKTFNVSVDHNNSSQQQNLNKNINLNVKPIYNNKYNSNNNNIDYNDNNSYGINNNKGNKITHHPFLNKSSKDKPDFTDDELNKAFELELPSKIFISESLKNNYADDINMKKKMKKQRTDKVGLSSNEYNSYKVEIQSNVSYEHAKKLHQLWNIYVNELLELSSNNELSLDTINDMELNGAYVEIHKSRCSTYIGIKGIIVLETQNSFKIITPKNKVLILLKNKSVFIIKIKERLYYLHGIQLMRDPALKSSKKYKMLQSRII</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRF1</accession>
    <name>A0A1J1GRF1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Potassium channel, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">K2</name>
        <name evidence="15" type="ORF">PGAL8A_00224900</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527667.1">
        <property type="nucleotide sequence ID" value="XM_028670967.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730776"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00224900"/>
    <dbReference type="OMA" id="WLFEIKS"/>
    <dbReference type="OrthoDB" id="10035564at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005267">
        <property type="term" value="F:potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003929">
        <property type="entry name" value="K_chnl_BK_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047871">
        <property type="entry name" value="K_chnl_Slo-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10027">
        <property type="entry name" value="CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10027:SF10">
        <property type="entry name" value="SLOWPOKE 2, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03493">
        <property type="entry name" value="BK_channel_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10 15" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0631">Potassium channel</keyword>
    <keyword evidence="3" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="44"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="183"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="278"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="323"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="348"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="Potassium channel" evidence="14">
        <location>
            <begin position="286"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="Calcium-activated potassium channel BK alpha subunit" evidence="13">
        <location>
            <begin position="525"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="673"/>
            <end position="692"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF07885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG94852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1385" mass="165456" checksum="D0C0477441711404" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRH7</accession>
    <name>A0A1J1GRH7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00242400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527839.1">
        <property type="nucleotide sequence ID" value="XM_028671159.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRH7"/>
    <dbReference type="GeneID" id="39730952"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00242400"/>
    <dbReference type="OMA" id="NNTPFFK"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013380394" evidence="1">
        <location>
            <begin position="25"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="164" mass="20212" checksum="B68A19D5D83061EE" modified="2017-02-15" version="1">MLRFNLIFFLKFFFFFYLVKDCTNKKLERSITNKYNCFFFFFKINNTPFFKKKLNNTKKNLLKARKIDQKKIKRIKNYQYAIKHMYDKNGKRIKQINKEKKSLKKKKLFDYEGFKVDKIFTCLSEEDMEELREEELKRKSGEILYNNKYIDNYGVESENDINEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRJ7</accession>
    <name>A0A1J1GRJ7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">NIF3</name>
        <name evidence="10" type="ORF">PGAL8A_00162100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526733.1">
        <property type="nucleotide sequence ID" value="XM_028675175.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730146"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00162100"/>
    <dbReference type="OMA" id="EYTHDAV"/>
    <dbReference type="OrthoDB" id="10249888at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008420">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17729">
        <property type="entry name" value="BRCT_CTDP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039189">
        <property type="entry name" value="Fcp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081">
        <property type="entry name" value="RNA POLYMERASE II CTD PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081:SF36">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="9">
        <location>
            <begin position="970"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="8">
        <location>
            <begin position="1186"/>
            <end position="1275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="196"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="266"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="368"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="786"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1374"/>
            <end position="1417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="62"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="196"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="210"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="271"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="788"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1392"/>
            <end position="1409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG93912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1417" mass="166994" checksum="4754DEC33B123565" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRT4</accession>
    <name>A0A1J1GRT4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00258600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527994.1">
        <property type="nucleotide sequence ID" value="XM_028671331.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRT4"/>
    <dbReference type="GeneID" id="39731115"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00258600"/>
    <dbReference type="OMA" id="RPRKYWI"/>
    <dbReference type="OrthoDB" id="369348at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="266" mass="30892" checksum="7C0DD5D4833CA240" modified="2017-02-15" version="1">MKKIFLFGIIFTTIIDLNKNILEEEIKKYMQNFLFLKNSQKYCEKDNLILAQTTDKLFNLSKVLDICVSKKTCDFISYSPKRKLRNSIFYENDEPLKNTGANWICSGDSWIFSRPRKYWITAIKDNHIKDQIKNYNVIDLNKTGECDEKNVLIKITNFITPKEVAEECNKISNCKFIIFNYNKKLGSSSKLNEKAVLCSQPPINRISKLGFFIAGKYVDSSSNQKKENKKKKKMIVNIPVGGSITPDNHYYNYNKGDLVHAEKLDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRW0</accession>
    <name>A0A1J1GRW0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter E family member 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ABCE1</name>
        <name evidence="5" type="ORF">PGAL8A_00174700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526861.1">
        <property type="nucleotide sequence ID" value="XM_028670072.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRW0"/>
    <dbReference type="GeneID" id="39730274"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00174700"/>
    <dbReference type="OMA" id="MVCIQNG"/>
    <dbReference type="OrthoDB" id="6593433at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060255">
        <property type="term" value="P:regulation of macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03236">
        <property type="entry name" value="ABC_RNaseL_inhibitor_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03237">
        <property type="entry name" value="ABC_RNaseL_inhibitor_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000144">
        <property type="entry name" value="ATP-binding cassette sub-family E member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000152">
        <property type="entry name" value="ATP-binding cassette, sub-family E, member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013283">
        <property type="entry name" value="RLI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034348">
        <property type="entry name" value="RLI_dom_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007209">
        <property type="entry name" value="RNaseL-inhib-like_metal-bd_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009945">
        <property type="entry name" value="PRK13409.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19248">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04068">
        <property type="entry name" value="Fer4_RLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01868">
        <property type="entry name" value="ABCEFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54862">
        <property type="entry name" value="4Fe-4S ferredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="60"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="3">
        <location>
            <begin position="84"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="3">
        <location>
            <begin position="339"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="619" mass="70207" checksum="D77BA0F7715928F3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS32</accession>
    <name>A0A1J1GS32_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00248500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527899.1">
        <property type="nucleotide sequence ID" value="XM_028671226.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS32"/>
    <dbReference type="GeneID" id="39731013"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00248500"/>
    <dbReference type="OrthoDB" id="376948at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="762"/>
            <end position="789"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="893" mass="105567" checksum="2F67F84F32ACDE6F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSG1</accession>
    <name>A0A1J1GSG1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00169400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526808.1">
        <property type="nucleotide sequence ID" value="XM_028670014.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSG1"/>
    <dbReference type="GeneID" id="39730221"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00169400"/>
    <dbReference type="OMA" id="MITEMIF"/>
    <dbReference type="OrthoDB" id="371040at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="987" mass="120519" checksum="7EC23B1D63F1810E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSL0</accession>
    <name>A0A1J1GSL0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tryptophan/threonine-rich plasmodium antigen C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00265800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000035">
        <property type="protein sequence ID" value="CRG95455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528266.1">
        <property type="nucleotide sequence ID" value="XM_028671633.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSL0"/>
    <dbReference type="GeneID" id="39731187"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00265800"/>
    <dbReference type="OMA" id="TQWEDWI"/>
    <dbReference type="OrthoDB" id="370547at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022089">
        <property type="entry name" value="Plasmodium-antigen_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12319">
        <property type="entry name" value="TryThrA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="Tryptophan/threonine-rich plasmodium antigen C-terminal" evidence="4">
        <location>
            <begin position="109"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="72"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="343" mass="43483" checksum="2280B1EA7196E669" modified="2017-02-15" version="1">MNDITKSPISSPNSTAENDRNSPGAQNEIFDVFYVYLSLSLILVFAFLQLFSDYILMKIQEQSCESMMLEGKNDDEMNDKEIEEEVEREENKKEAGSNIKEEWKKNERSKWMGQVENDWKEWLVEIENEKCNWIIEKESEWNEWMKNEEKKWIDWNKKMEEVFAYNEWEECMGWDRDEWIKWMEEKWMDFMIGNFKEWIKSCEVFMLNLMNTIWRNWKDKKLIEWLRKDWKQKEDDYWDNWEKKKWKRWILIKERKKWIKWKERIYLENIEWKKWIEGKEDEINRQEKWWAWIKWKQEKLVYLKNWMKLIENQWIKEERWKEWKNKRENMNKEKNNVNEVNEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GST7</accession>
    <name>A0A1J1GST7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00407200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527189.1">
        <property type="nucleotide sequence ID" value="XM_028670437.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732602"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00407200"/>
    <dbReference type="OMA" id="CKENCRT"/>
    <dbReference type="OrthoDB" id="386658at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="622"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1094"/>
            <end position="1116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1145"/>
            <end position="1165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1520"/>
            <end position="1550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="622"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1094"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1145"/>
            <end position="1156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1520"/>
            <end position="1538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1691" mass="202542" checksum="032051BA17A778A8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSV6</accession>
    <name>A0A1J1GSV6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00013500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528177.1">
        <property type="nucleotide sequence ID" value="XM_028671535.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSV6"/>
    <dbReference type="GeneID" id="39728657"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00013500"/>
    <dbReference type="OMA" id="FNYICID"/>
    <dbReference type="OrthoDB" id="378304at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1187" mass="143855" checksum="F237C3FAFB47E1DB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT42</accession>
    <name>A0A1J1GT42_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Serine C-palmitoyltransferase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00287300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528484.1">
        <property type="nucleotide sequence ID" value="XM_028671875.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT42"/>
    <dbReference type="GeneID" id="39731406"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00287300"/>
    <dbReference type="OMA" id="MDCWIVI"/>
    <dbReference type="OrthoDB" id="65434at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017059">
        <property type="term" value="C:serine palmitoyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004758">
        <property type="term" value="F:serine C-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046512">
        <property type="term" value="P:sphingosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050087">
        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693">
        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF3">
        <property type="entry name" value="LD36009P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="4">
        <location>
            <begin position="204"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="573" mass="65243" checksum="0A5979AA08F0BE1E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT96</accession>
    <name>A0A1J1GT96_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00272000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000041">
        <property type="protein sequence ID" value="CRG95520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528329.1">
        <property type="nucleotide sequence ID" value="XM_028671703.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT96"/>
    <dbReference type="GeneID" id="39731252"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00272000"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="222" mass="27268" checksum="A74BA4B271A64958" modified="2017-02-15" version="1" fragment="single">PDKYKNPYNYWFKFKVPIFWERFKNETNQMDHEWKLKKWNGDFRIFSNTKFNDLYSIIRSNIPDKQKKEKIDSFMNEFDSEFNKFLFECKKEMRDNKKESESKKEMREDKTESESEEEMTDNKTESESKKEMIDDKTESESKKEMIDNKTESESMKEMIENKTEFECKNEMRGNKTESEPKKEMIDDKTESEYRKEQGTNDIKNYKKKIWELLIVLIILRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTB3</accession>
    <name>A0A1J1GTB3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA-directed DNA polymerase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00296800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528564.1">
        <property type="nucleotide sequence ID" value="XM_028671963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTB3"/>
    <dbReference type="GeneID" id="39731501"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00296800"/>
    <dbReference type="OMA" id="KEHYICN"/>
    <dbReference type="OrthoDB" id="2320933at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050474">
        <property type="entry name" value="Hel308_SKI2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961">
        <property type="entry name" value="DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961:SF6">
        <property type="entry name" value="DNA-DIRECTED DNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="85"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="323"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="825" mass="98627" checksum="6D66E7B25D017CC4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTB9</accession>
    <name>A0A1J1GTB9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">26S proteasome regulatory subunit, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00274100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit S9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528353.1">
        <property type="nucleotide sequence ID" value="XM_028671729.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTB9"/>
    <dbReference type="GeneID" id="39731273"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00274100"/>
    <dbReference type="OrthoDB" id="1418352at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.570:FF:000015">
        <property type="entry name" value="26S proteasome regulatory subunit RPN6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050871">
        <property type="entry name" value="26S_Proteasome/COP9_Components"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040773">
        <property type="entry name" value="Rpn6_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10678">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18055">
        <property type="entry name" value="RPN6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0647">Proteasome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="3">
        <location>
            <begin position="392"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="613" mass="72092" checksum="9C2B80DBC316E6F5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTM3</accession>
    <name>A0A1J1GTM3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LsmAD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00307200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528668.1">
        <property type="nucleotide sequence ID" value="XM_028672079.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTM3"/>
    <dbReference type="GeneID" id="39731605"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00307200"/>
    <dbReference type="OrthoDB" id="2275718at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034063">
        <property type="term" value="P:stress granule assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045117">
        <property type="entry name" value="ATXN2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009604">
        <property type="entry name" value="LsmAD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025852">
        <property type="entry name" value="SM_dom_ATX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12854">
        <property type="entry name" value="ATAXIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12854:SF7">
        <property type="entry name" value="ATAXIN-2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06741">
        <property type="entry name" value="LsmAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14438">
        <property type="entry name" value="SM-ATX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01272">
        <property type="entry name" value="LsmAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LsmAD" evidence="2">
        <location>
            <begin position="173"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="305"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="814" mass="94332" checksum="0F99ACA376CA8D3E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTU7</accession>
    <name>A0A1J1GTU7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-f protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00186300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000025">
        <property type="protein sequence ID" value="CRG94468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527288.1">
        <property type="nucleotide sequence ID" value="XM_028670547.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTU7"/>
    <dbReference type="GeneID" id="39730390"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00186300"/>
    <dbReference type="OrthoDB" id="384111at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="590" mass="70958" checksum="E40902096AF3261D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU32</accession>
    <name>A0A1J1GU32_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-i protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00320700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000047">
        <property type="protein sequence ID" value="CRG95994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528802.1">
        <property type="nucleotide sequence ID" value="XM_028672229.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU32"/>
    <dbReference type="GeneID" id="39731740"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00320700"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="377" mass="45987" checksum="9FAAC5CB761A1B50" modified="2017-02-15" version="1">MDLKLSDATSIDSNDNLNGGNSTVDFAHREIEGATVSIPENPLYDDLDLRDAIQNPSEDINLDSTSSTNLHHKNLLSIFHLVMIIISFLRFARTYSPKLRAKHKERVRLQNKWDNRDKKMKGDWKKMEEKWNERKQKENREKEELNKKKEEREKKTNNEMEQFNRKWDGENYSEEKSWKFLNYSCINGKCIKSFNEPSTSQTCNKIVKRKKKNKVLLDIIEEKLKGISFKKPLSEDELIKKITEEEKKRREMLFRQVVELDEKWKKYEEHSIMRVKWEKDKRKKLEEKRRKRKEKHEEDMRKKHEEWEKSMIEKIKEWEKSMIEEFEKWEKSKIEKSEKWKKKENMKVNEEECRLNLKWKYELDKIKAIEGKKIRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU57</accession>
    <name>A0A1J1GU57_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Gamete antigen 27/25, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00411500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000055">
        <property type="protein sequence ID" value="CRG96065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528870.1">
        <property type="nucleotide sequence ID" value="XM_028672304.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU57"/>
    <dbReference type="GeneID" id="39732645"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00411500"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3030.10">
        <property type="entry name" value="Gametocyte protein Pfg27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015299">
        <property type="entry name" value="Gamete_antigen_PLAspp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036469">
        <property type="entry name" value="Pfg27_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09216">
        <property type="entry name" value="Pfg27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89162">
        <property type="entry name" value="Gametocyte protein Pfg27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="112" mass="13284" checksum="E5E24544EB011BF1" modified="2017-02-15" version="1">MSKINITRECQNFTVNEELRDNMTFRIQNRFSDYCLDVALTDEYCLKLKNIFSIEQQAFEEVFLDIHKKKIINEKLHNSAVRIGKFVNDFNFLSLTYSKVLPIVPDDHNIHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU76</accession>
    <name>A0A1J1GU76_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00300700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528603.1">
        <property type="nucleotide sequence ID" value="XM_028672007.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU76"/>
    <dbReference type="GeneID" id="39731540"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00300700"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="324"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="409"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="447"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="476" mass="59025" checksum="A2758C43AD7CF66F" modified="2017-02-15" version="1">MYCILFNENENYNKSKYSIINYFKNNYKIKRDKIKIKHLIDGLKRIHSNYDKKIIDDIIKKVKKDDTKKERIKYIKITDFFNIFYDEKKKLLELCILQYNEMKNYSIRIEHFKKSFNFYENKRYIYEEKGILKINIKSIELIEKYIPEEIIYYRIMFRVLEKYDDIKFLVSGKKNKKIFFNKKMEFLIKDKIEYMYINISKKNIRKKEKYNIKIKLPLIFLCDQRKHSMKIKVHHLLLSEINATFQYIFSRKKLYDDILKEYECIKNKQIERIINYEKEVLKYQLHFISSDNDITTNLKDPNIYFSYFYFYLKNIFDNKYLCDYNLTIFLYIGILLSALSSFQRPLFIDHINLSISAFYNLKNILFNLKSKKRNIHQNLLLIKKKRKKKKKNYTNIFHSNNFFKNEKQYKHIFILLIISFIYDIIWFNDYFMCITLDFLENIQCICMIFNIFFILWKILYFINLFKYFVEYKILYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUL4</accession>
    <name>A0A1J1GUL4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nucleolar protein 56</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00345100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NOP5/NOP56 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529038.1">
        <property type="nucleotide sequence ID" value="XM_028672491.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUL4"/>
    <dbReference type="GeneID" id="39731981"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00345100"/>
    <dbReference type="OMA" id="PDNYMFA"/>
    <dbReference type="OrthoDB" id="6780543at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031428">
        <property type="term" value="C:box C/D methylation guide snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.4070:FF:000005">
        <property type="entry name" value="SnoRNA binding domain containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.4070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.90">
        <property type="entry name" value="Nop domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045056">
        <property type="entry name" value="Nop56/Nop58"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012974">
        <property type="entry name" value="NOP58/56_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042239">
        <property type="entry name" value="Nop_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002687">
        <property type="entry name" value="Nop_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036070">
        <property type="entry name" value="Nop_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012976">
        <property type="entry name" value="NOSIC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10894">
        <property type="entry name" value="NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10894:SF0">
        <property type="entry name" value="NUCLEOLAR PROTEIN 56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01798">
        <property type="entry name" value="Nop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08156">
        <property type="entry name" value="NOP5NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00931">
        <property type="entry name" value="NOSIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89124">
        <property type="entry name" value="Nop domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51358">
        <property type="entry name" value="NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Nop" evidence="7">
        <location>
            <begin position="294"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="450"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="523"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="450"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="477"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="523"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00040742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="555" mass="65069" checksum="7370A2559078D24A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUP9</accession>
    <name>A0A1J1GUP9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">MI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00216600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PDCD4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527584.1">
        <property type="nucleotide sequence ID" value="XM_028670875.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUP9"/>
    <dbReference type="GeneID" id="39730693"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00216600"/>
    <dbReference type="OMA" id="MNILSFE"/>
    <dbReference type="OrthoDB" id="414546at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003891">
        <property type="entry name" value="Initiation_fac_eIF4g_MI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039778">
        <property type="entry name" value="PDCD4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12626">
        <property type="entry name" value="PROGRAMMED CELL DEATH 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12626:SF0">
        <property type="entry name" value="PROGRAMMED CELL DEATH PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02847">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00544">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51366">
        <property type="entry name" value="MI"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="MI" evidence="8">
        <location>
            <begin position="75"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="MI" evidence="8">
        <location>
            <begin position="291"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="MI" evidence="8">
        <location>
            <begin position="455"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="217"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="275"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="229"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="586" mass="70175" checksum="A61125B9EA0F8B55" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV08</accession>
    <name>A0A1J1GV08_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">phosphoethanolamine N-methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.103</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PMT</name>
        <name evidence="10" type="ORF">PGAL8A_00254100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>N,N-dimethylethanolamine phosphate + S-adenosyl-L-methionine = phosphocholine + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25325"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58641"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:295975"/>
            <dbReference type="EC" id="2.1.1.103"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:25326"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>N-methylethanolamine phosphate + S-adenosyl-L-methionine = N,N-dimethylethanolamine phosphate + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25321"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57781"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58641"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.1.1.103"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:25322"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Phospholipid metabolism; phosphatidylcholine biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.103" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527949.1">
        <property type="nucleotide sequence ID" value="XM_028671281.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV08"/>
    <dbReference type="GeneID" id="39731069"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00254100"/>
    <dbReference type="OMA" id="WTRKIKD"/>
    <dbReference type="OrthoDB" id="8300214at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000234">
        <property type="term" value="F:phosphoethanolamine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44307">
        <property type="entry name" value="PHOSPHOETHANOLAMINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44307:SF2">
        <property type="entry name" value="PHOSPHOETHANOLAMINE METHYLTRANSFERASE ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="9">
        <location>
            <begin position="52"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="209"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG95136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="264" mass="30989" checksum="D2239BB64A4C428C" modified="2017-02-15" version="1">MENKFKIDKTFLETNQYTEEGIKSYEFIFGDNFISSGGLDATIKILSDIQLNENSKVLDIGSGLGGGCKYINDKYGAHVYGIDISENMVNIAKNRNSGNKKIEFEANDILLKDFPENTFDMIYSRDSILHLSLENKKKLFEKCYKWLKPNGIILVTDYCASKPENWDEEFKEYIKKRRYTLITVEEYKDLIVSCKFENVISKDISDMWLDLLEVEINKLEDKKEEFLKKFSQKEYNSLRDGWTRKIKDSKRKIQLWGYFKAVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV46</accession>
    <name>A0A1J1GV46_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Asparagine-rich antigen, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00337400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528961.1">
        <property type="nucleotide sequence ID" value="XM_028672405.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731904"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00337400"/>
    <dbReference type="OMA" id="DYKRRED"/>
    <dbReference type="OrthoDB" id="48651at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12254">
        <property type="entry name" value="RRM_hnRNPH_ESRPs_RBM12_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="88"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="313"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="383"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="643"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="768"/>
            <end position="1179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1237"/>
            <end position="1259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="313"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="383"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="444"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="646"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="768"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="797"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="839"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="869"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="881"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="906"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="953"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1096"/>
            <end position="1108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1115"/>
            <end position="1176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1237"/>
            <end position="1255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1292" mass="153061" checksum="7A4D57BC19569465" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV74</accession>
    <name>A0A1J1GV74_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00358600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529167.1">
        <property type="nucleotide sequence ID" value="XM_028672634.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV74"/>
    <dbReference type="GeneID" id="39732116"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00358600"/>
    <dbReference type="OMA" id="SMLYYIY"/>
    <dbReference type="OrthoDB" id="372589at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="180"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="291"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="390" mass="47242" checksum="E21C23C0D7602F6F" modified="2017-02-15" version="1">MNLDINFKKKNDLGEKKVIEINNINRIILDILCTEAIRKIKFILHILKELLKKKTNILHVYISNNIDHLSTENKRKQIFNSLQDQIELCENETHYNLIKKKIEKYIDSLSETNEILCQNSPTDRNIKENRNKVIEDGTLLLNIFRKIKKLDFSSVSDELNMFKDEQNLLLNLKQSVYHKKQIINILNEQIKEQIENTKKKKEKIEEKIEQIEKRKKIFFVKSMLYYIYKEEYVNAKVSNYNMNINLKYDSTKKSKETMEEDLKSYESINDYIKMFLNKRNDHLQNIHDELVDYYEKEKIKKNKELEEINNEIYNTIKSIESKKNKIIQYEEVNKLHETEEKTKMKKEIEKKEFLKQYNESILFLQHIGRNKIKDYEEKKKKLKKKTKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVC5</accession>
    <name>A0A1J1GVC5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein tyrosine phosphatase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PRL</name>
        <name evidence="3" type="ORF">PGAL8A_00340000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528987.1">
        <property type="nucleotide sequence ID" value="XM_028672435.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVC5"/>
    <dbReference type="GeneID" id="39731930"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00340000"/>
    <dbReference type="OMA" id="GIEVHSW"/>
    <dbReference type="OrthoDB" id="5632at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14500">
        <property type="entry name" value="PTP-IVa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000078">
        <property type="entry name" value="Protein tyrosine phosphatase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050561">
        <property type="entry name" value="PTP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23339">
        <property type="entry name" value="TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22785">
        <property type="entry name" value="Tc-R-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="1">
        <location>
            <begin position="56"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="2">
        <location>
            <begin position="130"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="214" mass="24864" checksum="65AE420BA091A92D" modified="2017-02-15" version="1">MQNPIDYKLFKSHDYCNKRDNSDQLFNCIDVKLFDMERYMGNANYDMDYLNPVLNHPTKIEHGKIKILILDAPTNDLLPLYIKEMKNYNVTDLVRTCEKTYNDREIERAGINVHELIFPDGDAPTDDIVNNWLTVVNNVIKNNCAVAVHCVAGLGRAPVLASIVLIEFGMDPIDAIVFIRERRKGAINKRQLQFLKSYKKKKKKKNCLRRCHFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVC9</accession>
    <name>A0A1J1GVC9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00364200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529223.1">
        <property type="nucleotide sequence ID" value="XM_028672696.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732172"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00364200"/>
    <dbReference type="OrthoDB" id="5355499at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="563"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1086"/>
            <end position="1109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1147"/>
            <end position="1181"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="900"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1086"/>
            <end position="1107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1147"/>
            <end position="1162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1163"/>
            <end position="1172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1377" mass="162612" checksum="615C806DFABE45CC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVJ0</accession>
    <name>A0A1J1GVJ0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00007200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528117.1">
        <property type="nucleotide sequence ID" value="XM_028671468.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVJ0"/>
    <dbReference type="GeneID" id="39728594"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00007200"/>
    <dbReference type="OMA" id="KCTENIY"/>
    <dbReference type="OrthoDB" id="6502734at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="497"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="178"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="645" mass="76704" checksum="34D7307C4E47BCD1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVK3</accession>
    <name>A0A1J1GVK3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00414800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529372.1">
        <property type="nucleotide sequence ID" value="XM_028672861.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732678"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00414800"/>
    <dbReference type="OMA" id="QKMNNFE"/>
    <dbReference type="OrthoDB" id="371224at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13369">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13369:SF0">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13679">
        <property type="entry name" value="Methyltransf_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase" evidence="1">
        <location>
            <begin position="612"/>
            <end position="723"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="938" mass="112714" checksum="C2982BA3F76AC8AD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVM6</accession>
    <name>A0A1J1GVM6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">valine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Valyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PGAL8A_00010500</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.9" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528149.1">
        <property type="nucleotide sequence ID" value="XM_028671503.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVM6"/>
    <dbReference type="GeneID" id="39728627"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00010500"/>
    <dbReference type="OMA" id="QLHAGHY"/>
    <dbReference type="OrthoDB" id="629407at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004832">
        <property type="term" value="F:valine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006438">
        <property type="term" value="P:valyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002303">
        <property type="entry name" value="Valyl-tRNA_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946:SF109">
        <property type="entry name" value="VALINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946">
        <property type="entry name" value="VALYL-TRNA SYNTHETASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00986">
        <property type="entry name" value="TRNASYNTHVAL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012610905" description="valine--tRNA ligase" evidence="11">
        <location>
            <begin position="19"/>
            <end position="1220"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="12">
        <location>
            <begin position="229"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="13">
        <location>
            <begin position="1010"/>
            <end position="1153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="593"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="602"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG95338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1220" mass="148781" checksum="A20190B176C413AC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVN1</accession>
    <name>A0A1J1GVN1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Autophagy-related protein 7, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ATG7</name>
        <name evidence="4" type="ORF">PGAL8A_00352800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529115.1">
        <property type="nucleotide sequence ID" value="XM_028672576.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVN1"/>
    <dbReference type="GeneID" id="39732058"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00352800"/>
    <dbReference type="OMA" id="FKMDISF"/>
    <dbReference type="OrthoDB" id="338614at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019778">
        <property type="term" value="F:Atg12 activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019779">
        <property type="term" value="F:Atg8 activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006995">
        <property type="term" value="P:cellular response to nitrogen starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032446">
        <property type="term" value="P:protein modification by small protein conjugation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.70">
        <property type="entry name" value="Ubiquitin-like modifier-activating enzyme ATG7 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032197">
        <property type="entry name" value="Atg7_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042522">
        <property type="entry name" value="Atg7_N_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF3">
        <property type="entry name" value="UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME ATG7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16420">
        <property type="entry name" value="ATG7_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like modifier-activating enzyme Atg7 N-terminal" evidence="3">
        <location>
            <begin position="36"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="2">
        <location>
            <begin position="806"/>
            <end position="1108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="561"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1219" mass="144661" checksum="5F5F8D52FCC30581" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVP3</accession>
    <name>A0A1J1GVP3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tubulin-specific chaperone, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00419600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the TBCB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529420.1">
        <property type="nucleotide sequence ID" value="XM_028672915.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVP3"/>
    <dbReference type="GeneID" id="39732728"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00419600"/>
    <dbReference type="OMA" id="DQYEQRT"/>
    <dbReference type="OrthoDB" id="2130750at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043014">
        <property type="term" value="F:alpha-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007023">
        <property type="term" value="P:post-chaperonin tubulin folding pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007021">
        <property type="term" value="P:tubulin complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01789">
        <property type="entry name" value="Ubl_TBCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.190">
        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036859">
        <property type="entry name" value="CAP-Gly_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000938">
        <property type="entry name" value="CAP-Gly_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045172">
        <property type="entry name" value="TBCB_Ubl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18916">
        <property type="entry name" value="DYNACTIN 1-RELATED MICROTUBULE-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14560">
        <property type="entry name" value="Ubiquitin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01052">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74924">
        <property type="entry name" value="Cap-Gly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50245">
        <property type="entry name" value="CAP_GLY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CAP-Gly" evidence="3">
        <location>
            <begin position="182"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="245" mass="29262" checksum="E447F5A4601C2FF2" modified="2017-02-15" version="1">MNNYIKVDLIHNLYKNKKWTEIKLNKFDKIENIKQKIYTHTGTPCDNMNLYAYDELNVEQTQVFLNNDKLCLNDYNVKDNYTIYIQEKSKTFTNDLYNIDDEENLEKLKHLKYKIKEEDYNKRPDNVRTFLRKLREKKKEENIKLNDNEQNTYNAYDEELYKIGGRCRVKMGDRRGILKYVGNLKNNSEIFVGVDLDEPLGNSDGFYHNQLLFECKGNKYGYIGNINSIEMGDFPPFDIMNLEEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVP8</accession>
    <name>A0A1J1GVP8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Alpha/beta hydrolase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00362000</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529201.1">
        <property type="nucleotide sequence ID" value="XM_028672672.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732150"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00362000"/>
    <dbReference type="OMA" id="HIYMISK"/>
    <dbReference type="OrthoDB" id="5086500at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052374">
        <property type="entry name" value="SERAC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182">
        <property type="entry name" value="PROTEIN SERAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182:SF2">
        <property type="entry name" value="PROTEIN SERAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="600"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="15"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="999"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="605"/>
            <end position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG96396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1384" mass="166561" checksum="F5B10E9FDFDB716B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVR0</accession>
    <name>A0A1J1GVR0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">26S proteasome regulatory subunit RPN7, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00356000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529147.1">
        <property type="nucleotide sequence ID" value="XM_028672612.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVR0"/>
    <dbReference type="GeneID" id="39732090"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00356000"/>
    <dbReference type="OMA" id="RLHCKVD"/>
    <dbReference type="OrthoDB" id="1452at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.570:FF:000005">
        <property type="entry name" value="26S proteasome regulatory subunit N7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019585">
        <property type="entry name" value="Rpn7/CSN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045135">
        <property type="entry name" value="Rpn7_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049549">
        <property type="entry name" value="RPN7_PSMD6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14145:SF1">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14145">
        <property type="entry name" value="26S PROTESOME SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10602">
        <property type="entry name" value="RPN7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21154">
        <property type="entry name" value="RPN7_PSMD6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 4" id="KW-0647">Proteasome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="3">
        <location>
            <begin position="198"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="33"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="394" mass="46581" checksum="9F635169E26A1478" modified="2017-02-15" version="1">MEKDNKEENYELNKDCYPNFYLADLFYNLQLSHISINERNETLQKLLDEIEKNNMYPYYSYICEELNLNIDQDLYKKLKDKADEEMNEIEKKILESSENFDSVETKNDLLIKANFFCKIGDKENSFKEYEEAYKKGIGIGVKLDILLTMIRISIFFNDLKNTKKYLEQAKTQMEKGGDWERKNKLKIYEALNYIMIRNFSEASKILIDAASTFTATEILSYDQLIFYVVILSIMTEERTVLNKKILNNSVILQVTSSDDDLQSYISSFYHCDYRTFMEKIIKIAIRVKRDKYIGRHYRYFIRNTRVRAYKQFLEPFKNVTLKNMAYAFGVSEEFIESEVSSFIANGKLNCKIDKVNGSIESNQPNERNTMYLNTIKKGDILLNRIQKLSRVIDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVZ6</accession>
    <name>A0A1J1GVZ6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00421800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529442.1">
        <property type="nucleotide sequence ID" value="XM_028672939.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVZ6"/>
    <dbReference type="GeneID" id="39732750"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00421800"/>
    <dbReference type="OMA" id="GHFHLAY"/>
    <dbReference type="OrthoDB" id="17317at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="807" mass="95710" checksum="27083811BBFFB541" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWB0</accession>
    <name>A0A1J1GWB0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Vacuolar protein sorting-associated protein 29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">VPS29</name>
        <name evidence="7" type="ORF">PGAL8A_00278600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the VPS29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528397.1">
        <property type="nucleotide sequence ID" value="XM_028671779.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWB0"/>
    <dbReference type="GeneID" id="39731319"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00278600"/>
    <dbReference type="OMA" id="VRGNMDY"/>
    <dbReference type="OrthoDB" id="10258130at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030904">
        <property type="term" value="C:retromer complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07394">
        <property type="entry name" value="MPP_Vps29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000015">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024654">
        <property type="entry name" value="Calcineurin-like_PHP_lpxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000979">
        <property type="entry name" value="Phosphodiesterase_MJ0936/Vps29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028661">
        <property type="entry name" value="Vps29"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00040">
        <property type="entry name" value="yfcE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11124">
        <property type="entry name" value="VACUOLAR SORTING PROTEIN VPS29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12850">
        <property type="entry name" value="Metallophos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="6">
        <location>
            <begin position="12"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="190" mass="21426" checksum="3DE7027FC18AAED5" modified="2017-02-15" version="1">MSGKLEDIGELVLLIGDFHSPIRNLGLPDCFKDLLKTDKIKHVLCTGNVGSRENLELLKNIADSVHITKGDMDDNYDFPEEISLNIGDFKISLIHGHQIIPWGNMNSLLQWQKKYDSDIIISGHTHKNSIVQYEGKYFINPGSATGAFQPWLAETVPSFILMAVAKNSIVVYVYEEKYGKTNVEMSELRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWD6</accession>
    <name>A0A1J1GWD6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00415400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529379.1">
        <property type="nucleotide sequence ID" value="XM_028672870.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWD6"/>
    <dbReference type="GeneID" id="39732685"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00415400"/>
    <dbReference type="OMA" id="YEVYSNA"/>
    <dbReference type="OrthoDB" id="372218at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="331" mass="39484" checksum="802E5ED21D52D538" modified="2017-02-15" version="1">MNYIESYRFQKKAPNLKSDLEENKDNWDEFIKYMNNLKNISYYPSKDSECIFNSYNEDDINTNENELNENIDDLIKLKKWNDMQIDNHSIYKESSSDIESNSNSSGSVLSFNKYNIIQNNIYSNNANFKRQKIKNNSYDYKPNENYEDEKNDSLSYVKSKNLLEFDDNKDNNEPYKNNKVQKKMYTKNNIENSSKNSLKNRNQKRNFNLNNHKSYDTNTYDNLVDGNNRDKSDNKKNYMNINIIKKNNKYEAGNYNRINQNKEKKFKKNSNIKKKKKKIENNLEIDGSYAYNYAYLNKNDESSVSSPMETVNNTIMNLEEEINNYQFNDFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWW6</accession>
    <name>A0A1J1GWW6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00433200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529555.1">
        <property type="nucleotide sequence ID" value="XM_028673064.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732864"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00433200"/>
    <dbReference type="OMA" id="KQTMLFY"/>
    <dbReference type="OrthoDB" id="377415at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="810"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="920"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1056"/>
            <end position="1100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1493" mass="181463" checksum="4A3BC6845D035747" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX60</accession>
    <name>A0A1J1GX60_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">tRNA-dihydrouridine synthase</fullName>
            <ecNumber evidence="13">1.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">PGAL8A_00280500</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>5,6-dihydrouridine(16) in tRNA + NAD(+) = uridine(16) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53380"/>
            <dbReference type="Rhea" id="RHEA-COMP:13543"/>
            <dbReference type="Rhea" id="RHEA-COMP:13544"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="11">
            <dbReference type="Rhea" id="RHEA:53382"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>5,6-dihydrouridine(16) in tRNA + NADP(+) = uridine(16) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53376"/>
            <dbReference type="Rhea" id="RHEA-COMP:13543"/>
            <dbReference type="Rhea" id="RHEA-COMP:13544"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="10">
            <dbReference type="Rhea" id="RHEA:53378"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>5,6-dihydrouridine(17) in tRNA + NAD(+) = uridine(17) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53372"/>
            <dbReference type="Rhea" id="RHEA-COMP:13541"/>
            <dbReference type="Rhea" id="RHEA-COMP:13542"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="9">
            <dbReference type="Rhea" id="RHEA:53374"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>5,6-dihydrouridine(17) in tRNA + NADP(+) = uridine(17) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53368"/>
            <dbReference type="Rhea" id="RHEA-COMP:13541"/>
            <dbReference type="Rhea" id="RHEA-COMP:13542"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.88"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="12">
            <dbReference type="Rhea" id="RHEA:53370"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 13 15">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the Dus family. Dus1 subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the dus family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.-" evidence="13"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528416.1">
        <property type="nucleotide sequence ID" value="XM_028671800.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX60"/>
    <dbReference type="GeneID" id="39731338"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00280500"/>
    <dbReference type="OMA" id="QRPHHDI"/>
    <dbReference type="OrthoDB" id="272303at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102262">
        <property type="term" value="F:tRNA-dihydrouridine16 synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102263">
        <property type="term" value="F:tRNA-dihydrouridine17 synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001269">
        <property type="entry name" value="DUS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11082">
        <property type="entry name" value="TRNA-DIHYDROURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11082:SF5">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(16_17) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006621">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 13" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 13 15" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DUS-like FMN-binding" evidence="16">
        <location>
            <begin position="26"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="14">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="29"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR006621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR006621-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR006621-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="CRG95608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="337" mass="39907" checksum="6FC46AEBD4ADA47E" modified="2017-02-15" version="1">MISDEYMHKKEYEKTFWEKIGKPKYILAPMVDLSELAFRLLCKKYNCHLSFTPMLHSKNFAQQEKYRISNFKSCEEDKPVIGQFCGNDSKIILDAIEFIKKDVNAVDLNFGCPQQIAKKGNYGAFLLHKHDEVVNLVSNITNNCNIPITCKIRKIDEDYQKTLNLCYDLQSRNVQMITIHGRTKEEKGKNIKNCDYEIIRIIKERLNIPIIANGSIENFEDIEKCLNYTKADAVMCAEILLEKPYFFSNKNIDTVDIVNEYYDLFLKYESNTKYLKGHLFKMLYKYFQIHTDLRDLLNNCYTLNDYLNFQVILNEKKKMGILMESPHSWYRRYRKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX87</accession>
    <name>A0A1J1GX87_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter B family member 7, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ABCB7</name>
        <name evidence="10" type="ORF">PGAL8A_00312200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528717.1">
        <property type="nucleotide sequence ID" value="XM_028672134.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX87"/>
    <dbReference type="GeneID" id="39731655"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00312200"/>
    <dbReference type="OMA" id="MYTGHTL"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03228">
        <property type="entry name" value="ABCC_MRP_Like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF1">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="258"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="288"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="373"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="147"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="468"/>
            <end position="768"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG95909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="771" mass="89256" checksum="2A1AB5D0B73A064B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXJ2</accession>
    <name>A0A1J1GXJ2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TMEM205-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00459400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529817.1">
        <property type="nucleotide sequence ID" value="XM_028673357.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXJ2"/>
    <dbReference type="GeneID" id="39733127"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00459400"/>
    <dbReference type="OMA" id="ISWGYLF"/>
    <dbReference type="OrthoDB" id="360207at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025423">
        <property type="entry name" value="TMEM205-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13664">
        <property type="entry name" value="DUF4149"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="TMEM205-like" evidence="6">
        <location>
            <begin position="43"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="210" mass="24021" checksum="3AB824DB338AA011" modified="2017-02-15" version="1">MGCTFSNLRCVTNFTGLSSLIISLFPNLIIKNPEILRPLLNVSWGYLFGSTFWLCFFSEVGVLRGLKDIKSLPLPENAEDAKRLLEEHKGMESDFNRRSVDFQYFFSLSTLFSGILLLSTVRLATHNIQLRISSSVVAISCLLNSLYFYNKIYKLKQTKVNLYNELIENPKSDTAMAALKKNKKEFHIYHGLSILSLYLSFFGLTPYIFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXL1</accession>
    <name>A0A1J1GXL1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">60S ribosomal protein L5, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00295700</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the universal ribosomal protein uL18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528560.1">
        <property type="nucleotide sequence ID" value="XM_028671959.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXL1"/>
    <dbReference type="GeneID" id="39731490"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00295700"/>
    <dbReference type="OMA" id="CQIASAH"/>
    <dbReference type="OrthoDB" id="1618453at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008097">
        <property type="term" value="F:5S rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00432">
        <property type="entry name" value="Ribosomal_L18_L5e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.100:FF:000002">
        <property type="entry name" value="60S ribosomal protein L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01337_A">
        <property type="entry name" value="Ribosomal_uL18_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005485">
        <property type="entry name" value="Rbsml_uL18_euk_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057268">
        <property type="entry name" value="Ribosomal_L18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025607">
        <property type="entry name" value="Ribosomal_uL18_C_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23410:SF12">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23410">
        <property type="entry name" value="RIBOSOMAL PROTEIN L5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14204">
        <property type="entry name" value="Ribosomal_L18_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17144">
        <property type="entry name" value="Ribosomal_L5e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00058">
        <property type="entry name" value="RIBOSOMALL5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53137">
        <property type="entry name" value="Translational machinery components"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6 11" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL18 C-terminal eukaryotes" evidence="10">
        <location>
            <begin position="235"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="245"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="245"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF14204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG95752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="294" mass="34252" checksum="9A58E5896BB3356A" modified="2017-02-15" version="1">MAYVKVVKNKAYFKRYQVKYRRRREGKTDYRARKALILQDKNKYNAQKLRFVVRKTNSQIICQIASAHIEGDKILAEAKSKELTKYGIPVGLKNYAAAYATGLLCARRFLKSLNLDSQFVGVERVTEQIEDKEEKEDEDSRKPIKAFLDVGITMTTTGNRVFAALKGACDGGLHIPHGNNRFPGSKNEFNPEQLRKNILGIHVAEYMKTLKEEDNEKYKAHFNEYIKNNIDPDNIEQMYLSAHEKIRQNPERKEKNKDKTKKFLSKHEKPKKLNAKIRKKRVKEKLAKYVEKLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY50</accession>
    <name>A0A1J1GY50_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00506300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530291.1">
        <property type="nucleotide sequence ID" value="XM_028673883.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY50"/>
    <dbReference type="GeneID" id="39733596"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00506300"/>
    <dbReference type="OrthoDB" id="372226at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="143" mass="17073" checksum="AA81E734D952218C" modified="2017-02-15" version="1">MKKNLVILYFIIFTFSHILTVNTIQRSLKGNLKNGNRNNRDLHKEEYLMNFEIMKDKNNISYMQLNSSTFFNILASTRLMRNSGGAMSQPPIYRYVPNLHDHNENIGASLVFFMFMILIFFVVFFIFYFIFKHHVKHIKFMNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY95</accession>
    <name>A0A1J1GY95_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00485800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530081.1">
        <property type="nucleotide sequence ID" value="XM_028673650.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY95"/>
    <dbReference type="GeneID" id="39733391"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00485800"/>
    <dbReference type="OrthoDB" id="370651at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="71" mass="8149" checksum="22A42421B791FAAE" modified="2017-02-15" version="1">MYSSQYYSYDTIYRPYYPGYVLYEIPQEKNIFCSLTEALCSGIGLIITSLASICVASTDLLIRSCDNRKNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYF3</accession>
    <name>A0A1J1GYF3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00325300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000053">
        <property type="protein sequence ID" value="CRG96040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528848.1">
        <property type="nucleotide sequence ID" value="XM_028672280.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYF3"/>
    <dbReference type="GeneID" id="39731786"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00325300"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="296"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="334" mass="38794" checksum="F818345F259A3FB3" modified="2017-02-15" version="1">MALLYNEGCENSEKDITECNVTACVLHGSKFKSVECDPAFKKVIKYSQKNSGDDIKKNIFVFEDTPPPYWDDTKITFLSQDSNRDIVFLYEVNPKNGYASSLVFLCRLRNLKPGLSLCQQVDKSYVERPLSFYTIDVLDRDNENNFPNGLKYLKNERHATRKARYDQIFFSKDSCHYVTDSNSSEQVCRYSVCKKYPNGALSCKDAKFNGRLCQLEPSNGVKEPTKFIYLPNDCIKGDSNYCTPYLCQYEEPNELYPCSKLEISAVKGLMPHSQRQALEYRQNRYISNEDNNSSSLIAMSFFPFLILFFFIGCYLYKVLRKNRKKKRYATYKEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYH3</accession>
    <name>A0A1J1GYH3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00328000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000056">
        <property type="protein sequence ID" value="CRG96067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528872.1">
        <property type="nucleotide sequence ID" value="XM_028672306.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYH3"/>
    <dbReference type="GeneID" id="39731810"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00328000"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="226" mass="28461" checksum="DFDB0A7230DD213B" modified="2017-02-15" version="1">MLEKQKRIWKQWLKKQRMWFILHSEDEWFNNLLEQYEEEEESMKRITKKDTKKEKEIHENIEELKQVGDNEIEKNRKKREKLIQKVLIEIHMTLLEECMKDELQREKEYFFKKMVEELKIQENLDEDVNILEIKKKSRNVILNNDKEKIEEWKKKKWFIELILEMKNKEKEYMKEVYEDIIAKKNEDRIRNPMLERQKIIWKKHCEDIHKKWIEKNNKECFTTVIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYX4</accession>
    <name>A0A1J1GYX4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00523200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530457.1">
        <property type="nucleotide sequence ID" value="XM_028674067.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYX4"/>
    <dbReference type="GeneID" id="39733765"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00523200"/>
    <dbReference type="OrthoDB" id="370932at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1050.10">
        <property type="entry name" value="At2g23090-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039713">
        <property type="entry name" value="At2g23090-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039438">
        <property type="entry name" value="At2g23090-like_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007513">
        <property type="entry name" value="SERF-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026939">
        <property type="entry name" value="ZNF706/At2g23090_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33788">
        <property type="entry name" value="OS07G0114300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33788:SF1">
        <property type="entry name" value="ZINC-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04419">
        <property type="entry name" value="SERF-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12907">
        <property type="entry name" value="zf-met2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118359">
        <property type="entry name" value="Expressed protein At2g23090/F21P24.15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Small EDRK-rich factor-like N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="At2g23090-like zinc-binding" evidence="3">
        <location>
            <begin position="37"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="71" mass="8277" checksum="4B0CEB8E2FD28108" modified="2017-02-15" version="1">MTRGNQREVDRIRSSKRNDKAKPNSTVKDASKNLNVICKLCKHTFMCTVNQSILKDHHEKKHSKNAYEDCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ85</accession>
    <name>A0A1J1GZ85_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00031300</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530677.1">
        <property type="nucleotide sequence ID" value="XM_028674312.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ85"/>
    <dbReference type="GeneID" id="39728836"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00031300"/>
    <dbReference type="OMA" id="GMVEYWR"/>
    <dbReference type="OrthoDB" id="271386at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000003">
        <property type="entry name" value="Peptidylprolyl isomerase domain and WD repeat-containing 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF4">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE DOMAIN AND WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0697">Rotamase</keyword>
    <keyword evidence="3 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="144"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="9">
        <location>
            <begin position="589"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="90"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG97878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="737" mass="85660" checksum="37209143F1CE44FD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZB3</accession>
    <name>A0A1J1GZB3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mitochondrial import inner membrane translocase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00024100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the small Tim family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530606.1">
        <property type="nucleotide sequence ID" value="XM_028674233.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZB3"/>
    <dbReference type="GeneID" id="39728764"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00024100"/>
    <dbReference type="OMA" id="CFEKCFG"/>
    <dbReference type="OrthoDB" id="7813104at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.810">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit tim13 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004217">
        <property type="entry name" value="Tim10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035427">
        <property type="entry name" value="Tim10-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02953">
        <property type="entry name" value="zf-Tim10_DDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144122">
        <property type="entry name" value="Tim10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="1" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="1" id="KW-0653">Protein transport</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0811">Translocation</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Tim10-like" evidence="2">
        <location>
            <begin position="17"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU367043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="82" mass="9475" checksum="BC55974249DE54CB" modified="2017-02-15" version="1">MDNPRSMEDAQNALGMMIYQILNNQVRKTCFEKCFGQKFSEQMGKNEQICLAKCMDRMYEAHTIVTKASTEIAQNLNIDTNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZQ7</accession>
    <name>A0A1J1GZQ7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00436800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529589.1">
        <property type="nucleotide sequence ID" value="XM_028673103.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZQ7"/>
    <dbReference type="GeneID" id="39732900"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00436800"/>
    <dbReference type="OMA" id="INIEQMN"/>
    <dbReference type="OrthoDB" id="4726at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008143">
        <property type="term" value="F:poly(A) binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12306">
        <property type="entry name" value="RRM_II_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236:SF92">
        <property type="entry name" value="POLYADENYLATE-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="71"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="202" mass="23347" checksum="ACD47F0E69380E43" modified="2017-02-15" version="1">MEQINIDQMNPEKGKNDGGNFKVQVDDINNIDKEFSDLQKLKMMNEGAEMQMNQNSTLDSHEMEQEEINNRSIFVGNVDYSTQPEELQSLFSECGLINRVTILVNKNTGHSKGYAYIEFADASSVRTALSLSESFFKKRQIKVCSKRRNIPGFNRPKINAYRGRAMKTTLNTRGRLRQPTFRPFYRGRGVYKKIITNPYERT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZS4</accession>
    <name>A0A1J1GZS4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioredoxin-like protein 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">TLP2</name>
        <name evidence="2" type="ORF">PGAL8A_00438300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529605.1">
        <property type="nucleotide sequence ID" value="XM_028673120.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZS4"/>
    <dbReference type="GeneID" id="39732916"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00438300"/>
    <dbReference type="OMA" id="ANSMPTF"/>
    <dbReference type="OrthoDB" id="10263751at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050620">
        <property type="entry name" value="Thioredoxin_H-type-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10438">
        <property type="entry name" value="THIOREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10438:SF468">
        <property type="entry name" value="THIOREDOXIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="4"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="127" mass="14960" checksum="8D6F46136CA16EC0" modified="2017-02-15" version="1">MYSLKFYNKIRHYSLGRLSRRNLYTELNNMDDYLKKVNGEKLVVAQFGASWCAPCKKMKPLIKQLGEDNENIETLYIDIDEFPELGENEDINELPTFLLRKNGKYLDKIIGTNEKELIKSIEKHQKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZT0</accession>
    <name>A0A1J1GZT0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00022600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530592.1">
        <property type="nucleotide sequence ID" value="XM_028674217.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZT0"/>
    <dbReference type="GeneID" id="39728749"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00022600"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="323" mass="38823" checksum="1F508879599B0781" modified="2017-02-15" version="1">MALLYNEGCENFEEDSAICRMSICSIKQNKFEKSFCNLDKKLVKVHRPLNNVSNDISRNIFKYERYVPYRSSRIIILSDNNQDGIVFLYEYNIYNDPYPTKTYLCRLRNINQTAALCESVDIYYLDKRLYFSSYDFISEKNDQPLKHLKNPNHKIIKSKYKDLFIKEHSCHHIKTRYISRRSCMYAICEKKNEDYMLCSDANYSGKLIFLDDRNPINRKFIYLPEGCLKIYPNFACNAYFCEIHAKDNFFPCEYKEISAIKDIMPYSKRSEVMPIKQQIVHHEDNLSASALFAMTLMPFLILFVFFWCYIYKYFKKRRRRKIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZW8</accession>
    <name>A0A1J1GZW8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA-binding chaperone, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00531500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530538.1">
        <property type="nucleotide sequence ID" value="XM_028674157.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZW8"/>
    <dbReference type="GeneID" id="39733848"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00531500"/>
    <dbReference type="OMA" id="QRWEVIS"/>
    <dbReference type="OrthoDB" id="1690618at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051083">
        <property type="term" value="P:'de novo' cotranslational protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006450">
        <property type="term" value="P:regulation of translational fidelity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054076">
        <property type="entry name" value="ZUO1-like_ZHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044634">
        <property type="entry name" value="Zuotin/DnaJC2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43999">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43999:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23082">
        <property type="entry name" value="Myb_DNA-binding_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21884">
        <property type="entry name" value="ZUO1-like_ZHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="157"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="107"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="414"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="528"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="586"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="699"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="194"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="534"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="588"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="699"/>
            <end position="734"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="911" mass="108212" checksum="574950E73C46A5B4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H010</accession>
    <name>A0A1J1H010_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00032600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530688.1">
        <property type="nucleotide sequence ID" value="XM_028674324.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H010"/>
    <dbReference type="GeneID" id="39728849"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00032600"/>
    <dbReference type="OMA" id="INYNEEC"/>
    <dbReference type="OrthoDB" id="10585219at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012385040" description="Apple domain-containing protein" evidence="3">
        <location>
            <begin position="19"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="134"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="284"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="134"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="185"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="602" mass="72511" checksum="E46D69346CF3EC6E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H015</accession>
    <name>A0A1J1H015_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00065300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028531011.1">
        <property type="nucleotide sequence ID" value="XM_028674683.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H015"/>
    <dbReference type="GeneID" id="39729178"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00065300"/>
    <dbReference type="OrthoDB" id="10567176at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="279" mass="34544" checksum="97EBFE12F3576C2E" modified="2017-02-15" version="1">MLNTTLHPIIKKSINYENFFLGINNINVNHCNKYYFSKKEEKCKRIYYANNTINIFVLLFLLSLLYFFLQSTFKLQGQVICILGLNRNYPRKLIEREYFYRKKNNFNELKRRISEEEIYDMWCRYMNYMEEEDCNDIYIKIEEEWKNITEEYKIEKKWSKKILKVWYTELSRELLYKYLQEYRELENKQNDTYTLGDHIEFLNEKLNQWRNDRYIIMDKWKTFREEATHIWNEYILETSEKEEKGNNEKVIESLKKRISISEKQEIKNDTKNCKSSVIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H027</accession>
    <name>A0A1J1H027_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">orotate phosphoribosyltransferase</fullName>
            <ecNumber evidence="5">2.4.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">OPRT</name>
        <name evidence="11" type="ORF">PGAL8A_00034100</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.10" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530704.1">
        <property type="nucleotide sequence ID" value="XM_028674341.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H027"/>
    <dbReference type="GeneID" id="39728865"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00034100"/>
    <dbReference type="OMA" id="ANVFYLY"/>
    <dbReference type="OrthoDB" id="5553476at2759"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00119"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004588">
        <property type="term" value="F:orotate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046132">
        <property type="term" value="P:pyrimidine ribonucleoside biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01208">
        <property type="entry name" value="PyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023031">
        <property type="entry name" value="OPRT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004467">
        <property type="entry name" value="Or_phspho_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00336">
        <property type="entry name" value="pyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46683">
        <property type="entry name" value="OROTATE PHOSPHORIBOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46683:SF1">
        <property type="entry name" value="OROTATE PHOSPHORIBOSYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="69"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="10">
        <location>
            <begin position="77"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG97905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="240" mass="28286" checksum="0100553B3ACE75D0" modified="2017-02-15" version="1">MRNGNTVNILSDEEINKKYVELKNKINLENDEDDCHIKEMKHLLKIVCLKYKAIKFGDFILKSKRKSKYFFSSGVLNNVISANIISFLISHLILKKNFKFDYLLGASYKGIPIATLTSYFLFSSNKYHNVFYLYDRKEKKEYGDKNDIIGILEDNNINEEKKIIIIDDVFTCGTALGEILNKLKHYNNLKVIAIIVLFNRNEYNINENNEKIYFKDLFEQKFNIPLYSILNYNEDFDHLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0A7</accession>
    <name>A0A1J1H0A7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00031900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530682.1">
        <property type="nucleotide sequence ID" value="XM_028674317.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0A7"/>
    <dbReference type="GeneID" id="39728842"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00031900"/>
    <dbReference type="OMA" id="ERNVEPF"/>
    <dbReference type="OrthoDB" id="383990at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="349" mass="40925" checksum="A014193592C00316" modified="2017-02-15" version="1">MNSLLFKNKASNNEMDKIFNENNEAIISIENKKIVFPHKFKKCIIQNAFSSVLSPLKIEHNNILTKNSKISNIFSPRKKKTKLKNREDIYKKEASVKYNKEISFSNNINLCNMELFDNNNFESQINNKIMKKKFFERNFYSKYSNLENFSTDEVNDILENYDYSTNYIIKNRDFKDFQGKHDSKLTNKIGNINNLYSNKIQIINYNINFVEHNSVVNPIIQHECNRKFPNGKWIMENDKINKEIKTFHNCNITADTKLNRENSIYVNCENELQKIHSLSLKDMDTKVTGDSIKQVSEVVDTSRQHFSICDDISPLIKKKIKKGKKKNKGACFFNLNNFSCQFLMSCSKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0G6</accession>
    <name>A0A1J1H0G6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cation-transporting ATPase</fullName>
            <ecNumber evidence="13">7.2.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">ATPase1</name>
        <name evidence="17" type="ORF">PGAL8A_00037600</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Membrane</location>
            <topology evidence="1 13">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.-" evidence="13"/>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530738.1">
        <property type="nucleotide sequence ID" value="XM_028674379.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728900"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00037600"/>
    <dbReference type="OMA" id="FQIFAMI"/>
    <dbReference type="OrthoDB" id="425043at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140358">
        <property type="term" value="F:P-type transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000023">
        <property type="entry name" value="Cation-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006544">
        <property type="entry name" value="P-type_TPase_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047819">
        <property type="entry name" value="P5A-ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630:SF8">
        <property type="entry name" value="CATION-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630">
        <property type="entry name" value="CATION-TRANSPORTING ATPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12409">
        <property type="entry name" value="P5-ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="244"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="278"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="580"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1822"/>
            <end position="1844"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1850"/>
            <end position="1869"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1890"/>
            <end position="1914"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1972"/>
            <end position="1996"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="2016"/>
            <end position="2036"/>
        </location>
    </feature>
    <feature type="domain" description="P5B-type ATPase N-terminal" evidence="16">
        <location>
            <begin position="37"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="15">
        <location>
            <begin position="314"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="457"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF12409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="CRG97939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2076" mass="244762" checksum="21417071E8E3AC53" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0L9</accession>
    <name>A0A1J1H0L9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00441000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529632.1">
        <property type="nucleotide sequence ID" value="XM_028673150.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0L9"/>
    <dbReference type="GeneID" id="39732943"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00441000"/>
    <dbReference type="OrthoDB" id="371809at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="332"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="148"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="592" mass="72931" checksum="FFB4A3BB5CE7D90A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0R9</accession>
    <name>A0A1J1H0R9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosome biogenesis protein NSA2 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00048000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the pre-66S ribosomal particle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
            <location evidence="1 6">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530842.1">
        <property type="nucleotide sequence ID" value="XM_028674495.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0R9"/>
    <dbReference type="GeneID" id="39729005"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00048000"/>
    <dbReference type="OMA" id="AHVIHPE"/>
    <dbReference type="OrthoDB" id="1847590at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030684">
        <property type="term" value="C:preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11381">
        <property type="entry name" value="NSA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.310:FF:000001">
        <property type="entry name" value="NSA2, ribosome biogenesis homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039411">
        <property type="entry name" value="NSA2_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022309">
        <property type="entry name" value="Ribosomal_Se8/biogenesis_NSA2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12642">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN NSA2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01201">
        <property type="entry name" value="Ribosomal_S8e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 6" id="KW-0698">rRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG98045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="259" mass="30323" checksum="7911DA564A24DA59" modified="2017-02-15" version="1">MPQNDYIELHRKRYGYRFDYFEKLRKKEARKVHKESLKAKKLRGIKAKIYNKKRYTEKINLKKTIKSHELKDVKSVEKIRDENGLPSYLLDRNQIKHTQILTNLIKQKRKNKAGKWQLPIPKIQALNEAEMLRVVKSGKRRKKTWKRLIDKISFVGNDFTRKNPKFERYIRPSSLRFKKANVYHSELKATFSLDIISVKVNPQSNLYTNLGIITKGTIIEVNVSELGLVTQSGKVIWAKFAQVTNNPELDGCINASLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H100</accession>
    <name>A0A1J1H100_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerase</fullName>
            <ecNumber evidence="2">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">rpoD</name>
        <name evidence="11" type="ORF">PGAL8A_API04100</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <geneLocation type="apicoplast" evidence="11"/>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 13">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="2"/>
    <dbReference type="EMBL" id="LN835293">
        <property type="protein sequence ID" value="CRG98251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009325478.1">
        <property type="nucleotide sequence ID" value="NC_031963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H100"/>
    <dbReference type="GeneID" id="30315775"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_API04100"/>
    <dbReference type="OMA" id="FEYCFIY"/>
    <dbReference type="OrthoDB" id="498011at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Apicoplast API"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038120">
        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376:SF54">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0933">Apicoplast</keyword>
    <keyword evidence="3" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-0934">Plastid</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="455"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="494"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb1" evidence="10">
        <location>
            <begin position="164"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG98251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="526" mass="64099" checksum="882591E5CF22FB37" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H174</accession>
    <name>A0A1J1H174_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Exported serine/threonine protein kinase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">EST</name>
        <name evidence="4" type="ORF">PGAL8A_00065200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028531010.1">
        <property type="nucleotide sequence ID" value="XM_028674682.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729177"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00065200"/>
    <dbReference type="OrthoDB" id="377209at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36593">
        <property type="entry name" value="EXPORTED SERINE/THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36593:SF1">
        <property type="entry name" value="EXPORTED SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="1158"/>
            <end position="1623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="377"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1827"/>
            <end position="1853"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="475"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="726"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1749"/>
            <end position="1777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="392"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1835"/>
            <end position="1853"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG98213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2393" mass="284156" checksum="BBB91102D8B43BD0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H180</accession>
    <name>A0A1J1H180_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DEAD/DEAH box ATP-dependent RNA helicase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00462500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529848.1">
        <property type="nucleotide sequence ID" value="XM_028673391.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H180"/>
    <dbReference type="GeneID" id="39733158"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00462500"/>
    <dbReference type="OMA" id="QIYEVAQ"/>
    <dbReference type="OrthoDB" id="1191041at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00268">
        <property type="entry name" value="DEADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044742">
        <property type="entry name" value="DEAD/DEAH_RhlB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="87"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="389"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="726" mass="86369" checksum="4751FEC02173D77B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1L3</accession>
    <name>A0A1J1H1L3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GINS subunit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00499900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530228.1">
        <property type="nucleotide sequence ID" value="XM_028673813.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1L3"/>
    <dbReference type="GeneID" id="39733532"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00499900"/>
    <dbReference type="OMA" id="CIPCCVL"/>
    <dbReference type="OrthoDB" id="374114at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000811">
        <property type="term" value="C:GINS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902975">
        <property type="term" value="P:mitotic DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11713">
        <property type="entry name" value="GINS_A_psf3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021151">
        <property type="entry name" value="GINS_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010492">
        <property type="entry name" value="GINS_Psf3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038437">
        <property type="entry name" value="GINS_Psf3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22768">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22768:SF0">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05916">
        <property type="entry name" value="Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GINS subunit" evidence="1">
        <location>
            <begin position="97"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="202" mass="23835" checksum="DABF7E43F173BA3B" modified="2017-02-15" version="1">MNNEIILNEKLEELKNLIYVDETPFKHLDFKVPCVPCCVLPGLSFLSARAMEEYKNGYRKDEINENDEIYIEYFYAKRLHKNNLVKIRFPEYYEMAGALLSDATAAAVGNLSHLYFELGNELCEILPENEWPVEKLEDLLLIAEIRRRLYLIKHNDQVDQTYLEGMTYMERKMFNSFSMGTDLEKEKASSNRDIFNFFELDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1R7</accession>
    <name>A0A1J1H1R7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">H/ACA ribonucleoprotein complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">GAR1</name>
        <name evidence="10" type="ORF">PGAL8A_00505600</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
            <location evidence="1 8">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the GAR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530284.1">
        <property type="nucleotide sequence ID" value="XM_028673875.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1R7"/>
    <dbReference type="GeneID" id="39733589"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00505600"/>
    <dbReference type="OrthoDB" id="2187159at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031429">
        <property type="term" value="C:box H/ACA snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034513">
        <property type="term" value="F:box H/ACA snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000454">
        <property type="term" value="P:snoRNA guided rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.230:FF:000001">
        <property type="entry name" value="H/ACA ribonucleoprotein complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.230">
        <property type="entry name" value="Probable tRNA pseudouridine synthase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038664">
        <property type="entry name" value="Gar1/Naf1_Cbf5-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007504">
        <property type="entry name" value="H/ACA_rnp_Gar1/Naf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23237:SF6">
        <property type="entry name" value="H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23237">
        <property type="entry name" value="NUCLEOLAR PROTEIN FAMILY A MEMBER 1 SNORNP PROTEIN GAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04410">
        <property type="entry name" value="Gar1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 8" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="115"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="123"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="157"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG97483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="207" mass="24786" checksum="C0452D23DDB5EAA2" modified="2017-02-15" version="1">MGFFRKNRKQNYNRNNENEVKLDKIILGGTFYKYCENDLVIKNKLENLVPYFNGRIFLENKEEIGKVDEILGPINEFYFSVKLKEGIRAKSFSSDTKFFIDSSQTLPLSRFLPQCKKVENTPKKKKKSNRDKKKNTFNTNINKSQNFSYRGGNNNERNNRNDRNNRNNRNDRNNRNDRNNRNDRNNRNNFKNRSNSSRKFSNQRGRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1T2</accession>
    <name>A0A1J1H1T2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00506400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530292.1">
        <property type="nucleotide sequence ID" value="XM_028673884.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1T2"/>
    <dbReference type="GeneID" id="39733597"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00506400"/>
    <dbReference type="OrthoDB" id="10543588at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="502" mass="60578" checksum="E60C7ED45766C1EA" modified="2017-02-15" version="1">MIAVRLKCSEDMKELNMSKIEDNSKEIIMKGIEDLEKINEINKINIKKNDEHSKEKLENKKFQKLTCLVKNDDPKNSILSELDCFSKNKSSFAEKKNCIKNNLVFKNKILELIKNGEKDKNIWFDQNENSHNFVKRSDITEKKKPNYVYDIGKNKRNETLKKYKDSIFKDLQKEIKNNSNKNNKKKVVLKMLHNKLNNFELDKFNDYKYINSSKSIVFEKEKNTELKSTRDNNFKKNFIEHYDEKNILNYKQLQYKNKEVKRKNKKENIKRNKSHIFSYFYKSNPSKFSKYDKNVFPKSMSDYIKENINEKNGVDIKEKTYTMNDQTGSEGKKKDKRNKRDEIRSDIGKEDKNINIENNKDINKKKKKKNFKNERGQRKKEEEEEEEEEKNEDEDEEEEEEEKENEEEEKKEDEEEEEEEEKKVKEKEKENEKEKLQNSVELVDEKKKKKTKGKLNKKKNFILINIKKVKNYKNNHYISKIVNSSYYLKKNCDKKFSEHRFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H227</accession>
    <name>A0A1J1H227_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Dynamin-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">DYN2</name>
        <name evidence="5" type="ORF">PGAL8A_00496100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530184.1">
        <property type="nucleotide sequence ID" value="XM_028673764.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H227"/>
    <dbReference type="GeneID" id="39733494"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00496100"/>
    <dbReference type="OMA" id="IQRRKEC"/>
    <dbReference type="OrthoDB" id="5061070at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1240">
        <property type="entry name" value="Dynamin, middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003130">
        <property type="entry name" value="GED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF21">
        <property type="entry name" value="DYNAMIN RELATED PROTEIN 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02212">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00302">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="4">
        <location>
            <begin position="23"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="GED" evidence="3">
        <location>
            <begin position="613"/>
            <end position="703"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="703" mass="80484" checksum="952C5FA24FD699EF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2I9</accession>
    <name>A0A1J1H2I9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">proline--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Prolyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00528400</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>tRNA(Pro) + L-proline + ATP = L-prolyl-tRNA(Pro) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:14305"/>
            <dbReference type="Rhea" id="RHEA-COMP:9700"/>
            <dbReference type="Rhea" id="RHEA-COMP:9702"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78532"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.15"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.15" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530508.1">
        <property type="nucleotide sequence ID" value="XM_028674124.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2I9"/>
    <dbReference type="GeneID" id="39733817"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00528400"/>
    <dbReference type="OMA" id="GINYIAH"/>
    <dbReference type="OrthoDB" id="1350766at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017101">
        <property type="term" value="C:aminoacyl-tRNA synthetase multienzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004827">
        <property type="term" value="F:proline-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006433">
        <property type="term" value="P:prolyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00862">
        <property type="entry name" value="ProRS_anticodon_zinc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00778">
        <property type="entry name" value="ProRS_core_arch_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.110.30:FF:000001">
        <property type="entry name" value="Bifunctional glutamate/proline--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000007">
        <property type="entry name" value="Bifunctional glutamate/proline--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.800:FF:000005">
        <property type="entry name" value="bifunctional glutamate/proline--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.30">
        <property type="entry name" value="C-terminal domain of ProRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.960.10">
        <property type="entry name" value="YbaK/aminoacyl-tRNA synthetase-associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01571">
        <property type="entry name" value="Pro_tRNA_synth_type3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002316">
        <property type="entry name" value="Pro-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004499">
        <property type="entry name" value="Pro-tRNA-ligase_IIa_arc-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016061">
        <property type="entry name" value="Pro-tRNA_ligase_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017449">
        <property type="entry name" value="Pro-tRNA_synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033721">
        <property type="entry name" value="ProRS_core_arch_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036754">
        <property type="entry name" value="YbaK/aa-tRNA-synt-asso_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007214">
        <property type="entry name" value="YbaK/aa-tRNA-synth-assoc-dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00408">
        <property type="entry name" value="proS_fam_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43382:SF2">
        <property type="entry name" value="BIFUNCTIONAL GLUTAMATE_PROLINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43382">
        <property type="entry name" value="PROLYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09180">
        <property type="entry name" value="ProRS-C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04073">
        <property type="entry name" value="tRNA_edit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01046">
        <property type="entry name" value="TRNASYNTHPRO"/>
    </dbReference>
    <dbReference type="SMART" id="SM00946">
        <property type="entry name" value="ProRS-C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64586">
        <property type="entry name" value="C-terminal domain of ProRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55826">
        <property type="entry name" value="YbaK/ProRS associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="9">
        <location>
            <begin position="251"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG97707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="714" mass="83300" checksum="49C84D12420B970C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H392</accession>
    <name>A0A1J1H392_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcription factor with AP2 domain(S), putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ApiAp2</name>
        <name evidence="3" type="ORF">PGAL8A_00039400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530756.1">
        <property type="nucleotide sequence ID" value="XM_028674399.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728918"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00039400"/>
    <dbReference type="OMA" id="NTWNILW"/>
    <dbReference type="OrthoDB" id="387495at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2050">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="733"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="894"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1137"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="733"/>
            <end position="819"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1787" mass="215058" checksum="C101179697844993" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3J3</accession>
    <name>A0A1J1H3J3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="9">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PGAL8A_00035600</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. UvrD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="9"/>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530719.1">
        <property type="nucleotide sequence ID" value="XM_028674358.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3J3"/>
    <dbReference type="GeneID" id="39728880"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00035600"/>
    <dbReference type="OMA" id="GHNKNED"/>
    <dbReference type="OrthoDB" id="417752at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000725">
        <property type="term" value="P:recombinational repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.486.10">
        <property type="entry name" value="PCRA, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013986">
        <property type="entry name" value="DExx_box_DNA_helicase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070:SF2">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE SRS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00580">
        <property type="entry name" value="UvrD-helicase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 11 16" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="15">
        <location>
            <begin position="49"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="427"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="619"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="6"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="431"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="619"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="629"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="70"/>
            <end position="77"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="CRG97920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1127" mass="133438" checksum="F4B55172029953BB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H473</accession>
    <name>A0A1J1H473_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Mitochondrial carrier protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00058100</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530943.1">
        <property type="nucleotide sequence ID" value="XM_028674607.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H473"/>
    <dbReference type="GeneID" id="39729106"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00058100"/>
    <dbReference type="OrthoDB" id="409586at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990542">
        <property type="term" value="P:mitochondrial transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045315">
        <property type="entry name" value="Mtm1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45760">
        <property type="entry name" value="FI19922P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45760:SF2">
        <property type="entry name" value="FI19922P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="6"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="115"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG98146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="380" mass="45451" checksum="036B7925D8918197" modified="2017-02-15" version="1">MENRTINIQNIVYSSTVSSIFVSLICTPLDVIKNYIQYNNNISFDKKYILKKITKKKKNNLLKFNSFYYQTFKNIYNNYGIKAIYRGLVSTTNLYVINNTLFFYVYEELKEKGIPYYLSATISRFISIIITSPLELYKTNIQANVCNNYKITIFDIFKDKKNRKVKINIYKGITSTLIRDIPFSALYWSLNEYLVSYIKKNDTEFEKRKKFIKKFVYPFICGCLSSTITTFITHPLDIIKTNMQARCIDIIHKSEFDYRKIKNYDIYSRNKTNTFYNICQNNLYNNKYICDVKINNYAHNNHRSIYYKYGSHKYGCNTYSYKYYNYFKYTNNSNYNIFSVSKFIFKKNGIKGFYIGIFPRLVKIVPTCAILFSTYHYFNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2009-09-01" modified="2025-10-08" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>C6F1F7</accession>
    <name>C6F1F7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">DNA-directed RNA polymerase subunit</fullName>
            <ecNumber evidence="16">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">Rbp1</name>
        <name evidence="20" type="synonym">RPB1</name>
        <name evidence="20" type="ORF">PGAL8A_00398100</name>
    </gene>
    <organism evidence="19">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2009" name="J. Mol. Evol." volume="68" first="706" last="714">
            <title>An unusual recent expansion of the C-terminal domain of RNA polymerase II in primate malaria parasites features a motif otherwise found only in mammalian polymerases.</title>
            <authorList>
                <person name="Kishore S.P."/>
                <person name="Perkins S.L."/>
                <person name="Templeton T.J."/>
                <person name="Deitsch K.W."/>
            </authorList>
            <dbReference type="PubMed" id="19449052"/>
            <dbReference type="DOI" id="10.1007/s00239-009-9245-2"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="20 21" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15 16">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the RNA polymerase beta' chain family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="16"/>
    <dbReference type="EMBL" id="EU840284">
        <property type="protein sequence ID" value="ACJ53770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00398100"/>
    <dbReference type="OMA" id="QAFPIPH"/>
    <dbReference type="OrthoDB" id="270392at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02584">
        <property type="entry name" value="RNAP_II_Rpb1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02733">
        <property type="entry name" value="RNAP_II_RPB1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.40.20:FF:000019">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.132.30:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.390:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.860.120:FF:000003">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.180">
        <property type="entry name" value="RNA polymerase ii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.120">
        <property type="entry name" value="RNA polymerase II, clamp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="entry name" value="RNA polymerase Rpb1, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006592">
        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007080">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007083">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007075">
        <property type="entry name" value="RNA_pol_Rpb1_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007073">
        <property type="entry name" value="RNA_pol_Rpb1_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038593">
        <property type="entry name" value="RNA_pol_Rpb1_7_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044893">
        <property type="entry name" value="RNA_pol_Rpb1_clamp_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038120">
        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376:SF37">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04997">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05000">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04992">
        <property type="entry name" value="RNA_pol_Rpb1_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04990">
        <property type="entry name" value="RNA_pol_Rpb1_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 16 20" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 16 20" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="13 16" id="KW-0804">Transcription</keyword>
    <keyword evidence="6 16 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RNA polymerase N-terminal" evidence="18">
        <location>
            <begin position="266"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1115"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1181"/>
            <end position="1215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1510"/>
            <end position="1614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1628"/>
            <end position="1656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="2093"/>
            <end position="2115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="2167"/>
            <end position="2200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="1140"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="1181"/>
            <end position="1205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="1512"/>
            <end position="1529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="1530"/>
            <end position="1545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="1558"/>
            <end position="1573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="1574"/>
            <end position="1584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="1585"/>
            <end position="1595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="1599"/>
            <end position="1614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="2093"/>
            <end position="2107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="2167"/>
            <end position="2178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU004279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM00663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="ACJ53770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="CRG94277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2200" mass="251147" checksum="670F1F9E86C3E69E" modified="2009-09-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2012-05-16" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>H7CDX6</accession>
    <name>H7CDX6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Apicoplast ribosomal protein S8, putative</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Small subunit ribosomal protein 8</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rps8</name>
        <name evidence="3" type="synonym">RPS8</name>
        <name evidence="3" type="ORF">PGAL8A_API02000</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <geneLocation type="apicoplast" evidence="2"/>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Mol. Biol. Evol." volume="29" first="2095" last="2099">
            <title>The Plasmodium Apicoplast Genome: Conserved Structure and Close Relationship of P. ovale to Rodent Malaria Parasites.</title>
            <authorList>
                <person name="Arisue N."/>
                <person name="Hashimoto T."/>
                <person name="Mitsui H."/>
                <person name="Palacpac N.M.Q."/>
                <person name="Kaneko A."/>
                <person name="Kawai S."/>
                <person name="Hasegawa M."/>
                <person name="Tanabe K."/>
                <person name="Horii T."/>
            </authorList>
            <dbReference type="PubMed" id="22396524"/>
            <dbReference type="DOI" id="10.1093/molbev/mss082"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">A8</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">8A</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AB649424">
        <property type="protein sequence ID" value="BAL70746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LN835293">
        <property type="protein sequence ID" value="CRG98235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009325462.1">
        <property type="nucleotide sequence ID" value="NC_031963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="H7CDX6"/>
    <dbReference type="GeneID" id="30315795"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_API02000"/>
    <dbReference type="OMA" id="SFKYKFI"/>
    <dbReference type="OrthoDB" id="387228at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Apicoplast API"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035987">
        <property type="entry name" value="Ribosomal_uS8_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56047">
        <property type="entry name" value="Ribosomal protein S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0933">Apicoplast</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0934">Plastid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAL70746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="128" mass="16113" checksum="31D70ED736FC2573" modified="2012-05-16" version="1">MIVKFLNQFKYNLKLKKKFIFYKFSKIIYSIIILLYNYNYVLKFYIFKIDSKYFIFIILNKNKKINYFKIYIKYNQIFYINYNKLINFIKFYRYFKGLLILYSFKYKFITHLLSLKYKSGGILIFCIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL41</accession>
    <name>A0A1J1GL41_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00082200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525940.1">
        <property type="nucleotide sequence ID" value="XM_028670688.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL41"/>
    <dbReference type="GeneID" id="39729346"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00082200"/>
    <dbReference type="OrthoDB" id="548474at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070682">
        <property type="term" value="P:proteasome regulatory particle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038966">
        <property type="entry name" value="TMA17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40422">
        <property type="entry name" value="TRANSLATION MACHINERY-ASSOCIATED PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40422:SF1">
        <property type="entry name" value="TRANSLATION MACHINERY-ASSOCIATED PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="189" mass="21882" checksum="860C453C9889F32F" modified="2017-02-15" version="1">MVEIRLKTKNSSCEFNLDFSEVKIPDDINILKDLEKEIENSIYHLKRSNEEIKEFDPLGKDNDLFLALNENKFALSRKEERLQLIKKKIHNLESLNLLNEVSVCNDPLTNKDKKLEIGILNENDNSKDENNDSSIKNILSDNLNDENLYYDNSNQNYLCNKNLSGTIKDESETHSEKNTNALDENGIYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL84</accession>
    <name>A0A1J1GL84_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">mRNA-binding protein PUF1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PUF1</name>
        <name evidence="6" type="ORF">PGAL8A_00066100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG92957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525779.1">
        <property type="nucleotide sequence ID" value="XM_028672198.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL84"/>
    <dbReference type="GeneID" id="39729186"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00066100"/>
    <dbReference type="OMA" id="NMKNYNV"/>
    <dbReference type="OrthoDB" id="668540at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010608">
        <property type="term" value="P:post-transcriptional regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07920">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000237">
        <property type="entry name" value="Pumilio homolog 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033133">
        <property type="entry name" value="PUM-HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033712">
        <property type="entry name" value="Pumilio_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537:SF13">
        <property type="entry name" value="PUMILIO HOMOLOGY DOMAIN FAMILY MEMBER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537">
        <property type="entry name" value="RNA BINDING PROTEIN PUMILIO-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00806">
        <property type="entry name" value="PUF"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50302">
        <property type="entry name" value="PUM"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50303">
        <property type="entry name" value="PUM_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PUM-HD" evidence="5">
        <location>
            <begin position="465"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="488"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="524"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="597"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="633"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="669"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="705"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="741"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="844"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="995"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="69"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="859"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="881"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="899"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1004"/>
            <end position="1014"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG92957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1240" mass="144155" checksum="9D8A2A4BD13EB05B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL89</accession>
    <name>A0A1J1GL89_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">HIT-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00080400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525922.1">
        <property type="nucleotide sequence ID" value="XM_028670488.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL89"/>
    <dbReference type="GeneID" id="39729328"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00080400"/>
    <dbReference type="OMA" id="CVDENIN"/>
    <dbReference type="OrthoDB" id="272357at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070761">
        <property type="term" value="C:pre-snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000492">
        <property type="term" value="P:box C/D snoRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048254">
        <property type="term" value="P:snoRNA localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23023">
        <property type="entry name" value="zf-HIT_BCD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051639">
        <property type="entry name" value="BCD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007529">
        <property type="entry name" value="Znf_HIT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13483:SF3">
        <property type="entry name" value="BOX C_D SNORNA PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13483">
        <property type="entry name" value="BOX C_D SNORNA PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04438">
        <property type="entry name" value="zf-HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51083">
        <property type="entry name" value="ZF_HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="HIT-type" evidence="6">
        <location>
            <begin position="451"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="356"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="360"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="810" mass="96492" checksum="9814E7179F3C84D7" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLP7</accession>
    <name>A0A1J1GLP7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dolichol kinase</fullName>
            <ecNumber evidence="3">2.7.1.108</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00105750</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the polyprenol kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.108" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526174.1">
        <property type="nucleotide sequence ID" value="XM_028673287.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLP7"/>
    <dbReference type="GeneID" id="39729583"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00105750"/>
    <dbReference type="OMA" id="FCESYAL"/>
    <dbReference type="OrthoDB" id="377083at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004168">
        <property type="term" value="F:dolichol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043048">
        <property type="term" value="P:dolichyl monophosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032974">
        <property type="entry name" value="Polypren_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13205:SF15">
        <property type="entry name" value="DOLICHOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13205">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 15-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="43"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="206"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="273"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="303"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="347"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="401"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="448"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="490"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="526"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="553"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG93352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="593" mass="70807" checksum="BD4182C5E2C03571" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM74</accession>
    <name>A0A1J1GM74_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 14">Protein transport protein SEC23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="primary">SEC23</name>
        <name evidence="20" type="ORF">PGAL8A_00115800</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 14">Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Cytoplasmic vesicle</location>
            <location evidence="14">COPII-coated vesicle membrane</location>
            <topology evidence="14">Peripheral membrane protein</topology>
            <orientation evidence="14">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="14">Endoplasmic reticulum membrane</location>
            <topology evidence="14">Peripheral membrane protein</topology>
            <orientation evidence="14">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the SEC23/SEC24 family. SEC23 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526274.1">
        <property type="nucleotide sequence ID" value="XM_028674398.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM74"/>
    <dbReference type="GeneID" id="39729683"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00115800"/>
    <dbReference type="OMA" id="MPWNIIP"/>
    <dbReference type="OrthoDB" id="10256289at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030127">
        <property type="term" value="C:COPII vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090110">
        <property type="term" value="P:COPII-coated vesicle cargo loading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.730:FF:000005">
        <property type="entry name" value="Protein transport protein SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.380:FF:000016">
        <property type="entry name" value="Protein transport protein SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.20.10:FF:000041">
        <property type="entry name" value="Protein transport protein SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.410:FF:000008">
        <property type="entry name" value="Protein transport protein SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1670">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.730">
        <property type="entry name" value="Sec23/Sec24 helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.380">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012990">
        <property type="entry name" value="Beta-sandwich_Sec23_24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007123">
        <property type="entry name" value="Gelsolin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036180">
        <property type="entry name" value="Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037364">
        <property type="entry name" value="Sec23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006900">
        <property type="entry name" value="Sec23/24_helical_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036175">
        <property type="entry name" value="Sec23/24_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006896">
        <property type="entry name" value="Sec23/24_trunk_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006895">
        <property type="entry name" value="Znf_Sec23_Sec24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036174">
        <property type="entry name" value="Znf_Sec23_Sec24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11141">
        <property type="entry name" value="PROTEIN TRANSPORT PROTEIN SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11141:SF0">
        <property type="entry name" value="PROTEIN TRANSPORT PROTEIN SEC23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00626">
        <property type="entry name" value="Gelsolin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08033">
        <property type="entry name" value="Sec23_BS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04815">
        <property type="entry name" value="Sec23_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04811">
        <property type="entry name" value="Sec23_trunk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04810">
        <property type="entry name" value="zf-Sec23_Sec24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82754">
        <property type="entry name" value="C-terminal, gelsolin-like domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81811">
        <property type="entry name" value="Helical domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82919">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12 14" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 14" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 14" id="KW-0653">Protein transport</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 14" id="KW-0813">Transport</keyword>
    <keyword evidence="7 14" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zinc finger Sec23/Sec24-type" evidence="16">
        <location>
            <begin position="55"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 trunk" evidence="17">
        <location>
            <begin position="123"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 beta-sandwich" evidence="19">
        <location>
            <begin position="394"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 helical" evidence="18">
        <location>
            <begin position="509"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="domain" description="Gelsolin-like" evidence="15">
        <location>
            <begin position="622"/>
            <end position="710"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU365030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF08033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="CRG93452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="759" mass="86270" checksum="401EB7697B9A396D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM91</accession>
    <name>A0A1J1GM91_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">DNA-directed RNA polymerase 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00106200</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the archaeal RpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526179.1">
        <property type="nucleotide sequence ID" value="XM_028673344.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM91"/>
    <dbReference type="GeneID" id="39729588"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00106200"/>
    <dbReference type="OMA" id="HSEHIDI"/>
    <dbReference type="OrthoDB" id="282270at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001193">
        <property type="term" value="P:maintenance of transcriptional fidelity during transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006283">
        <property type="term" value="P:transcription-coupled nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10508">
        <property type="entry name" value="Zn-ribbon_RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019761">
        <property type="entry name" value="DNA-dir_RNA_pol-M_15_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012164">
        <property type="entry name" value="Rpa12/Rpb9/Rpc10/TFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001529">
        <property type="entry name" value="Zn_ribbon_RPB9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034012">
        <property type="entry name" value="Zn_ribbon_RPB9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001222">
        <property type="entry name" value="Znf_TFIIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239:SF1">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02150">
        <property type="entry name" value="Zn_ribbon_RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01096">
        <property type="entry name" value="Zn_ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00661">
        <property type="entry name" value="RPOL9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01030">
        <property type="entry name" value="RNA_POL_M_15KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51133">
        <property type="entry name" value="ZF_TFIIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 12" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIS-type" evidence="11">
        <location>
            <begin position="75"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="156"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG93357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="228" mass="27204" checksum="6DEFFAEFC7F83FDF" modified="2017-02-15" version="1">MAEVTFCEECNNILYARSDRKNKKLIYVCRSCEFISHKQNEEHNVVARINYNYNRKEDIYIHPETKNDPALGRVRDWKCKQCGNNEAVFLQLPEKISYNPMALIYVCTDKSCHYWEKEIQQKSDNLYKSDESSVSSQDNDSKLSIKEEISGDAIYGEKKNNVNNGTNRKNRKKLKKKKDEEDEDEEEEYQLKQELYKILNINEKEYNEEIKLKNENLYDLNVEEYFCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMF4</accession>
    <name>A0A1J1GMF4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">E3 ubiquitin protein ligase</fullName>
            <ecNumber evidence="14">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">TEX1</name>
        <name evidence="18" type="ORF">PGAL8A_00131900</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 14">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 14">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the BRE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="14"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526436.1">
        <property type="nucleotide sequence ID" value="XM_028674846.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMF4"/>
    <dbReference type="GeneID" id="39729844"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00131900"/>
    <dbReference type="OMA" id="DEMIIQI"/>
    <dbReference type="OrthoDB" id="10266039at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033503">
        <property type="term" value="C:HULC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16499">
        <property type="entry name" value="RING-HC_Bre1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013956">
        <property type="entry name" value="E3_ubiquit_lig_Bre1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23163:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE BRE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23163">
        <property type="entry name" value="RING FINGER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 14" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="11 14 15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 14" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9 14" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 13 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="17">
        <location>
            <begin position="975"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="476"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="148"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="378"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="527"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="640"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="752"/>
            <end position="824"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU365038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="CRG93614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1028" mass="122907" checksum="8342CD0474489C49" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMH2</accession>
    <name>A0A1J1GMH2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glideosome-associated protein 45, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">GAP45</name>
        <name evidence="2" type="ORF">PGAL8A_00123800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526353.1">
        <property type="nucleotide sequence ID" value="XM_028674753.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMH2"/>
    <dbReference type="GeneID" id="39729763"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00123800"/>
    <dbReference type="OMA" id="SKRCGCD"/>
    <dbReference type="OrthoDB" id="377174at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="196" mass="22728" checksum="40691DCDDDEAD32A" modified="2017-02-15" version="1">MGNYCRKNKVRDPKRKDIDELAERERLEKEAEKQREEQPEELEEQNEEPPEEPPENEEDQDDEDDKDDEPEEATQEESKSFEEKPIDDLDRSNSELYSESQQKYDNGSEKMETGTQLTLSTEATGAVQQVTKLSEPAHEESIYNTYRSVTPCDMNKVDETAKVFSRRCGCDLGDRHDENTCKICRKIDLSDTPLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMY7</accession>
    <name>A0A1J1GMY7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DnaJ protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00149100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526607.1">
        <property type="nucleotide sequence ID" value="XM_028675036.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMY7"/>
    <dbReference type="GeneID" id="39730015"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00149100"/>
    <dbReference type="OMA" id="NVIKMKH"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042407">
        <property type="term" value="P:cristae formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024586">
        <property type="entry name" value="DnaJ-like_C11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052243">
        <property type="entry name" value="Mito_inner_membrane_organizer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44157">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44157:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11875">
        <property type="entry name" value="DnaJ-like_C11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="69"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="356" mass="41952" checksum="A02FB96421CF3AD0" modified="2017-02-15" version="1">MYNANSEKEKSNETSGMDEKNKNINEVIDEVDTNVILQINSMNSENKKIFLNNYIAKIKYMNENYSKPRYYEILNVDVNSNVKTIRKSYLLLSKLLSVNKKLSSEYEECYYLIQKSYKILTDKFEKFYYDVLNNYIDESMIEEQRQILEKEANFIYENKINELKDEYYKKLKEEKEKNGLIIEKALFGNLSLKDECINNCFNINPITEDHIQGPFLDLTILLQCRIENSSLLFNDDVSFAYFLGIPKPLIKISSENKKSYVHILEDTEMHLYIKYKFLNVYHELIVVDRSTFTLPQSAHRVFGNHICGPFSPVNVIKLKHLSNSFMDNIFKFFSKNKVYITLFTTIILCAQSIKSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN27</accession>
    <name>A0A1J1GN27_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00143700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526553.1">
        <property type="nucleotide sequence ID" value="XM_028674975.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN27"/>
    <dbReference type="GeneID" id="39729961"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00143700"/>
    <dbReference type="OMA" id="IFKVPRY"/>
    <dbReference type="OrthoDB" id="376650at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="137" mass="16539" checksum="6DA55A668860D6C9" modified="2017-02-15" version="1">MDDSLFTIPRYIPEIDSNINEFNKINKEDENEHIINNNLKEKDNVTYNNELYKDSTKESNNLNYDTLEINEKMWFNNLIKKKEEIEITNIEESENDEEIIINTDNIFKNIYPFFKTEEDSNYLNQKKELKKNIKNMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN74</accession>
    <name>A0A1J1GN74_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA polymerase 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00153800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526650.1">
        <property type="nucleotide sequence ID" value="XM_028675083.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN74"/>
    <dbReference type="GeneID" id="39730062"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00153800"/>
    <dbReference type="OMA" id="KIYISWF"/>
    <dbReference type="OrthoDB" id="2320933at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1060.10">
        <property type="entry name" value="Taq DNA Polymerase, Chain T, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001098">
        <property type="entry name" value="DNA-dir_DNA_pol_A_palm_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002298">
        <property type="entry name" value="DNA_polymerase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10133">
        <property type="entry name" value="DNA POLYMERASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10133:SF62">
        <property type="entry name" value="DNA POLYMERASE THETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00476">
        <property type="entry name" value="DNA_pol_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00868">
        <property type="entry name" value="DNAPOLI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00482">
        <property type="entry name" value="POLAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA-directed DNA polymerase family A palm" evidence="1">
        <location>
            <begin position="815"/>
            <end position="1047"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1147" mass="135449" checksum="C4EA0BCDB7B825E8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN92</accession>
    <name>A0A1J1GN92_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">40S ribosomal protein S15, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RPS15</name>
        <name evidence="7" type="ORF">PGAL8A_00165300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526766.1">
        <property type="nucleotide sequence ID" value="XM_028675212.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN92"/>
    <dbReference type="GeneID" id="39730179"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00165300"/>
    <dbReference type="OMA" id="MHTRRKG"/>
    <dbReference type="OrthoDB" id="623277at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070181">
        <property type="term" value="F:small ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00353">
        <property type="entry name" value="Ribosomal_S15p_S13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.10:FF:000003">
        <property type="entry name" value="40S ribosomal protein S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.860.130:FF:000001">
        <property type="entry name" value="40S ribosomal protein S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01343_A">
        <property type="entry name" value="Ribosomal_uS15_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000589">
        <property type="entry name" value="Ribosomal_uS15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023029">
        <property type="entry name" value="Ribosomal_uS15_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012606">
        <property type="entry name" value="Ribosomal_uS15_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="uS15_NS1_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006331">
        <property type="entry name" value="PRK08561.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11885">
        <property type="entry name" value="RIBOSOMAL PROTEIN S15P/S13E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11885:SF6">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08069">
        <property type="entry name" value="Ribosomal_S13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00312">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01386">
        <property type="entry name" value="Ribosomal_S13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01387">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="S15/NS1 RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS15 N-terminal" evidence="6">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="151" mass="17261" checksum="8FF9E7832290BBAD" modified="2017-02-15" version="1">MGRMYGKGKGISSSTVPYKRKQPSWLKQKPSEIEDTIIKLAKKGQTPSQIGATLRDNYGIPQVKSVTGNKILRILRAHGVATTIPEDLYFLIKKAVSMRKHLEKNKKDKDCKFRLILTESKIHRISRYYKRKKLLPSNWKYQSSTASALIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNB1</accession>
    <name>A0A1J1GNB1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00154500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526657.1">
        <property type="nucleotide sequence ID" value="XM_028675091.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730069"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00154500"/>
    <dbReference type="OMA" id="LMYLEFF"/>
    <dbReference type="OrthoDB" id="376829at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="612"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="649"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="681"/>
            <end position="700"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1415" mass="170165" checksum="08ED3631E827BACA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNH9</accession>
    <name>A0A1J1GNH9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">NADH-cytochrome b5 reductase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00174000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526854.1">
        <property type="nucleotide sequence ID" value="XM_028670064.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNH9"/>
    <dbReference type="GeneID" id="39730267"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00174000"/>
    <dbReference type="OMA" id="DRPKPEW"/>
    <dbReference type="OrthoDB" id="432685at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06183">
        <property type="entry name" value="cyt_b5_reduct_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000042">
        <property type="entry name" value="Putative NADH-cytochrome b5 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001834">
        <property type="entry name" value="CBR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370:SF184">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00406">
        <property type="entry name" value="CYTB5RDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0274">FAD</keyword>
    <keyword evidence="3 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="7">
        <location>
            <begin position="44"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601834-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="328" mass="38942" checksum="AF0CBE9949F4CED6" modified="2017-02-15" version="1">MSIAFLSFFRKKDCAKNLFHIYSEKHAYEELDDKNEKTNVFLNKKKQILKLHKIIKLTKTVKIFIFSYPNEYEYLGLGICKHIKFSGLNKEGKIKGKWNNNDDKEKDLKQIFRSYTPIYIDKKNKHVHFVIRIYYPDDNYVDGGKMSMQLNNLKYNDKLEITGPFGLLEYKGNNEFVHLSKTIKNKKHIIMIAGGTGMTPFFRLINHLLLTENKEHSNIIYMTFIYANRNEEEILLKSIFDEYERKYENIKIVYSIDKCLDETKKNTFEHIGFINEELLKKYVLKYQKLDIKIENEDTLILLCGPPPMTTFLQKMLKDLNQLENIITL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNQ2</accession>
    <name>A0A1J1GNQ2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">U1 small nuclear ribonucleoprotein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00173600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526850.1">
        <property type="nucleotide sequence ID" value="XM_028670060.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNQ2"/>
    <dbReference type="GeneID" id="39730263"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00173600"/>
    <dbReference type="OMA" id="GRTTKGW"/>
    <dbReference type="OrthoDB" id="272703at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030619">
        <property type="term" value="F:U1 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12236">
        <property type="entry name" value="RRM_snRNP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000646">
        <property type="entry name" value="U1 small nuclear ribonucleoprotein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034143">
        <property type="entry name" value="snRNP70_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051183">
        <property type="entry name" value="U1_U11-U12_snRNP_70-35kDa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022023">
        <property type="entry name" value="U1snRNP70_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13952">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13952:SF5">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12220">
        <property type="entry name" value="U1snRNP70_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="98"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="221"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="261"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="289"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="379"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="401" mass="48851" checksum="793465442BE86B91" modified="2017-02-15" version="1">MSAIGMPPHILILFQARPLLNYYKPIKKKKPKEYSGLADFLNYFEEGEPPPKIKLENTKERKERKKKEKITYNELMLKEKRKNYDPFKNEDLTNDPKKTLFIGRLSYEVNEKRLRKEFETYGKIRKVKVICDKNNKPRGYAFVEFEHTKSLNQAYNLADGKKIDNRRILVDIERGRTIKNWLPRRLGGGKGPARGSEEKKRITHNINWSALINKDKYRNDKRRNDDRYKNVPLYNERNDDDDDIKYMLKNHKRHREDDRRSSKRERGHRSKRSASYDRHHHKHRRKEKSRLGRERSRDKEKIRDRSRERNRDRSRDRSRDRSRGRNRERDRERERERDRDREKEKGIEIESEMDKDKKREKDSFSDTESHNENSRNIEGENNNLHESTMKNAYYNYNNDIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNR5</accession>
    <name>A0A1J1GNR5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Falcilysin, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00167200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526785.1">
        <property type="nucleotide sequence ID" value="XM_028669988.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNR5"/>
    <dbReference type="GeneID" id="39730198"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00167200"/>
    <dbReference type="OMA" id="NYLYYIR"/>
    <dbReference type="OrthoDB" id="10250783at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013578">
        <property type="entry name" value="Peptidase_M16C_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055130">
        <property type="entry name" value="PreP_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43016">
        <property type="entry name" value="PRESEQUENCE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43016:SF13">
        <property type="entry name" value="PRESEQUENCE PROTEASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08367">
        <property type="entry name" value="M16C_assoc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22516">
        <property type="entry name" value="PreP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01264">
        <property type="entry name" value="M16C_associated"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M16C associated" evidence="1">
        <location>
            <begin position="558"/>
            <end position="864"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1147" mass="134084" checksum="EE4A89AF0223D863" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP29</accession>
    <name>A0A1J1GP29_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00175900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526873.1">
        <property type="nucleotide sequence ID" value="XM_028670085.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730286"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00175900"/>
    <dbReference type="OMA" id="IMLNYPH"/>
    <dbReference type="OrthoDB" id="16066at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2553" mass="308634" checksum="EA81643DE1DF530E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPA0</accession>
    <name>A0A1J1GPA0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00382800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526945.1">
        <property type="nucleotide sequence ID" value="XM_028670165.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPA0"/>
    <dbReference type="GeneID" id="39732358"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00382800"/>
    <dbReference type="OMA" id="NTEMNYN"/>
    <dbReference type="OrthoDB" id="28939at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009563">
        <property type="entry name" value="SSSCA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051888">
        <property type="entry name" value="UPF0148_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16537:SF1">
        <property type="entry name" value="PROTEIN ZNRD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16537">
        <property type="entry name" value="SJOEGREN SYNDROME/SCLERODERMA AUTOANTIGEN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06677">
        <property type="entry name" value="Auto_anti-p27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="268" mass="31829" checksum="C89F84A494E2A4D5" modified="2017-02-15" version="1">MKIENSIGNEPFSVSQIIGDKLLQGWTLLNSSCHICNITPLIKQKNKEERFCVRCNLFIKFEKSESEEDTNDIKEKNEKKEYKENVGDPIKYIKEIKLQNEEFNEILNKNNISKDEIQNLFEYKNYIKERCGYEVGEWLNFDKGYNHSVIKNENFELGNGDIKLKKENEFYSKYENKDFLQCEKPDLKGLKKKDISNTEMNYNKYSKLEEELCTLNKTKDVFINKLEKYLEYLNKSNNKNEEMEYINKISNVITILEKVNNLKKNIIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPA5</accession>
    <name>A0A1J1GPA5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Protein kinase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00394900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527066.1">
        <property type="nucleotide sequence ID" value="XM_028670300.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPA5"/>
    <dbReference type="GeneID" id="39732479"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00394900"/>
    <dbReference type="OrthoDB" id="541276at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050205">
        <property type="entry name" value="CDPK_Ser/Thr_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24349">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="202"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="19"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="314" mass="37416" checksum="8DCE778A735E5CD2" modified="2017-02-15" version="1">MGLCYPTKEKNTKYFHQGYILERRINKNDDSELYFAIFVKGNKERMVRKVNKNILKGITFDYLMKIRDFTYSNTLAIPNYLLKIYNLYEDNNSVYVITEKCTGGFLFDILKNNDCINERLLSEWFYQIITSLCFLEKNNIYHGNLNGYCIFFKDKNRKEIRLSLLSKNNKYDNIDQNGDLYGLFFIRSPQEIKRLYHDKNNTWYVGVLLFFLLFGSYPFISRNILKNYFKIVKNDIPFSTLKIRHNLSKNIYDFLEKALEKNYGKRPSLTELLNHPWITERNNHSEDNIINSITRKSANNQICVLEKDILKSVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPH5</accession>
    <name>A0A1J1GPH5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00179800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527230.1">
        <property type="nucleotide sequence ID" value="XM_028670482.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPH5"/>
    <dbReference type="GeneID" id="39730325"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00179800"/>
    <dbReference type="OrthoDB" id="6362699at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="323"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="355" mass="41839" checksum="0905844B3B2CFA0C" modified="2017-02-15" version="1">MALLYNRGCDDFEGDSVTCHMAICHINPYKFETSHCPVQLNSIKVYRPLDNVSNDISKNIFKYKRYGPYKFSRIIILSNNDQDGIVFLYELNPYMDNFPIKTYLCRLRSINQMLSLCESIDPYYLDKNLSFNSYDIINEKNDVGSLKHIKNPRHQIIISKYKDLFHKEHSCHLIKSKFFTQLRCVNYLCEKNNEEYNLCTDANYSGKLVFLDYDRYDKKIQDLIYLPESCLKKDSNFACTPYFCQKRDISQFSSCEYQEISAIKNIATNSKSLDVITTNSKSLDVITRNSKSLDLIPRNSKSLEVISTDPHNVYHENNLNAPALFAMTFMPFLILFVFFWCYIYKLMKKKRRKIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPQ1</accession>
    <name>A0A1J1GPQ1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Inner membrane complex protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00069800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG92994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525816.1">
        <property type="nucleotide sequence ID" value="XM_028673310.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPQ1"/>
    <dbReference type="GeneID" id="39729223"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00069800"/>
    <dbReference type="OMA" id="PYVTMDV"/>
    <dbReference type="OrthoDB" id="165382at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008521">
        <property type="entry name" value="Mg_trans_NIPA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570:SF9">
        <property type="entry name" value="MAGNESIUM TRANSPORTER NIPA8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05653">
        <property type="entry name" value="Mg_trans_NIPA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="251"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG92994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="461" mass="53083" checksum="108AAB1F06773220" modified="2017-02-15" version="1">MLTVIGSIFMAIANTFMKLGLSDSKKKKYFFSNYSCDMKWYVGFVVYCFGSFLHIIALGFAPASTLAPMNSFGLIANAIVANIYLHEKLGKIEIISTLGIFFGISICACASFLCETENVLFNPFNIIESWKNPWYIFYIFISIFLSFFTLIYLNYEENKIILGNEEIYAAKKYVELSVYDEKKEEIEESNMNSLINNKKINETLNIYPKSIGLSYGFLAGLIGSQCVLEIKEIVAFLNIGLTNKHIYKTPLPHLCFIFLVISIYLQIHFLNLGLTRGDATLVVPTYYVFWTFFGTLGGLVKFNEIQNFNFNSIILFLVGFVLTVLFISILAVQEITFLRKYVDKEVPDLPLENLDIHTQVLQNKKLSKQVLLNMGLFPVSLLGTTVGRKKFRPLYERFRRTRSILSDTHIGDQHCEYSIDNNIYNAYTLPYDIYNTNKDNFNDKKKKIRNNDKQVENTYIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPU4</accession>
    <name>A0A1J1GPU4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Erythrocyte membrane-associated antigen, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00192300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000029">
        <property type="protein sequence ID" value="CRG94525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527340.1">
        <property type="nucleotide sequence ID" value="XM_028670604.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730448"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00192300"/>
    <dbReference type="OMA" id="SCEPNHY"/>
    <dbReference type="OrthoDB" id="2274644at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05402">
        <property type="entry name" value="NT_PAP_TUTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="734"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1105"/>
            <end position="1128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1528"/>
            <end position="1569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1969"/>
            <end position="1995"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2680"/>
            <end position="2719"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="30"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="734"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="839"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="870"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1111"/>
            <end position="1120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1528"/>
            <end position="1538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1539"/>
            <end position="1549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1550"/>
            <end position="1561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1969"/>
            <end position="1982"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2683"/>
            <end position="2712"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="4566" mass="543597" checksum="C2E6F8258BBB7B8D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPV0</accession>
    <name>A0A1J1GPV0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pre-rRNA-processing protein TSR2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00102500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TSR2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526141.1">
        <property type="nucleotide sequence ID" value="XM_028672921.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPV0"/>
    <dbReference type="GeneID" id="39729550"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00102500"/>
    <dbReference type="OrthoDB" id="263560at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019398">
        <property type="entry name" value="Pre-rRNA_process_TSR2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21250">
        <property type="entry name" value="PRE-RRNA-PROCESSING PROTEIN TSR2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10273">
        <property type="entry name" value="WGG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="126"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="148" mass="17511" checksum="7774B2769A792291" modified="2017-02-15" version="1">MNDDTLILLNEGINLIFDKWTVLRLAVTNNWGGMNSEEKKKKLIEYVYNFVLSNNFRKNKLCDFLRDEMNTLFNVEIEDDSDIEIAELILELYENLKKKSFDILEKIRKIEVSDLSQSKEKELIDEVEVTDEEYSNSEYSDENYSNSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPW2</accession>
    <name>A0A1J1GPW2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00404400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAM136 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527161.1">
        <property type="nucleotide sequence ID" value="XM_028670405.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPW2"/>
    <dbReference type="GeneID" id="39732574"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00404400"/>
    <dbReference type="OMA" id="EMEGCVV"/>
    <dbReference type="OrthoDB" id="9975421at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008560">
        <property type="entry name" value="DUF842_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21096">
        <property type="entry name" value="PROTEIN FAM136A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21096:SF0">
        <property type="entry name" value="PROTEIN FAM136A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05811">
        <property type="entry name" value="DUF842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="154" mass="17756" checksum="3BB9B464A472EE03" modified="2017-02-15" version="1">MSFLSSPSTNHMITNLTKRTNEFQSKIDHILNTISTESLPFQKKSFVCCVNCFDTYNTDFESIGKCVNNCQKGTEHFVQVVQNEMQNLQNNLQSCQQSCFYKYSPNYAKSNASIDGPTIEKEMECCVVKCFDKHEPMLPEISDRLHKTLKEEMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPZ5</accession>
    <name>A0A1J1GPZ5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00189100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000026">
        <property type="protein sequence ID" value="CRG94496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527314.1">
        <property type="nucleotide sequence ID" value="XM_028670575.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPZ5"/>
    <dbReference type="GeneID" id="39730418"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00189100"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="243" mass="28889" checksum="D9257C73DBB7C9A5" modified="2017-02-15" version="1">MKTLTSYLKITTFILLIWMYQCFYNCYSYRTWIDENILQTKNELKYERVLTEGNTEEKKQTNAEGCLKERPLDNEKNKCKNPIQYKNPYDPCHGANTPSLSESFDRKAKEMNPKLRDQKLNIECNKISANQVSDLHFISHGPDIPDEEKSKITDSAKNQHDFKLDERLCESNKKMKDNKTEFDSNKELRGNKTESESKKEMTENKAESESKKEQRKKKKKNMKFDLMKHLIFHKFDKIYDDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ05</accession>
    <name>A0A1J1GQ05_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zinc finger protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00199600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527414.1">
        <property type="nucleotide sequence ID" value="XM_028670686.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ05"/>
    <dbReference type="GeneID" id="39730522"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00199600"/>
    <dbReference type="OMA" id="CDIKHHE"/>
    <dbReference type="OrthoDB" id="153872at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19821">
        <property type="entry name" value="Bbox1_BBX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19756">
        <property type="entry name" value="Bbox2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049808">
        <property type="entry name" value="CONSTANS-like_Bbox1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000315">
        <property type="entry name" value="Znf_B-box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31717">
        <property type="entry name" value="ZINC FINGER PROTEIN CONSTANS-LIKE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31717:SF45">
        <property type="entry name" value="ZINC FINGER PROTEIN CONSTANS-LIKE 14-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00336">
        <property type="entry name" value="BBOX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57845">
        <property type="entry name" value="B-box zinc-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50119">
        <property type="entry name" value="ZF_BBOX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="B box-type" evidence="5">
        <location>
            <begin position="251"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="269"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="B box-type" evidence="5">
        <location>
            <begin position="303"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="774"/>
            <end position="863"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG94599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1134" mass="135433" checksum="7454136FA13BA9D8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ16</accession>
    <name>A0A1J1GQ16_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ADP-ribosylation factor, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00201200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527430.1">
        <property type="nucleotide sequence ID" value="XM_028670704.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ16"/>
    <dbReference type="GeneID" id="39730538"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00201200"/>
    <dbReference type="OMA" id="KTHHWQI"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001166">
        <property type="entry name" value="ADP-ribosylation factor D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044612">
        <property type="entry name" value="ARL2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45697">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="23"/>
            <end position="30"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="125"/>
            <end position="128"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG94615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="185" mass="21657" checksum="32052CD16BBA704F" modified="2017-02-15" version="1">MVLLKILKKIKEKNKNIRIIILGLDNAGKTTIVKRLMGEDIYKVNPTFGFTIETLCFNNHFINIWDIGGQKSIRHFWKNYYENVDGIIYVIDSSDLFRIQLCSYELKQILKEERLYGCSLLILSNKIDIENSLNINQIVDILKLNEMNIDRHWCINECSAFSGKGLLKSFMWLVDDITSRLNNNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ20</accession>
    <name>A0A1J1GQ20_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00082600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525944.1">
        <property type="nucleotide sequence ID" value="XM_028670732.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729350"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00082600"/>
    <dbReference type="OMA" id="PLNVMTL"/>
    <dbReference type="OrthoDB" id="378074at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1284" mass="154942" checksum="AF59C04804E36DAD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ22</accession>
    <name>A0A1J1GQ22_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pre-mRNA-processing protein 45, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PRP45</name>
        <name evidence="3" type="ORF">PGAL8A_00409400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SNW family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527211.1">
        <property type="nucleotide sequence ID" value="XM_028670461.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ22"/>
    <dbReference type="GeneID" id="39732624"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00409400"/>
    <dbReference type="OMA" id="YGQRRGW"/>
    <dbReference type="OrthoDB" id="666364at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017862">
        <property type="entry name" value="SKI-int_prot_SKIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004015">
        <property type="entry name" value="SKI-int_prot_SKIP_SNW-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12096">
        <property type="entry name" value="NUCLEAR PROTEIN SKIP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02731">
        <property type="entry name" value="SKIP_SNW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SKI-interacting protein SKIP SNW" evidence="2">
        <location>
            <begin position="183"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="474" mass="56698" checksum="BFCAE3F5ADAEF9C0" modified="2017-02-15" version="1">MTDFLRNIPKPSKKYYNDLDENNIKEKILPKKEVTKNQCYEYLKRKHLRITCNEDFQGGGAYPEIHINQYPNNIGLKKTNNNDIVLKYIDENNNVKYDNLINEDVYIYNNNIDKIEQNERINKLRKKKILSDTKDREEKYNEPIYKPDDKEENEIIENTRKNIENILNEKLNKSIVNKKEEKYYRYIPQNKLNNNLEERILKVVEKSTDPLDVSKFRHKKLPNVKNSPDYPLLRSPTRKLNKEEENDWKIPPCVSNWKNNKGYNIPLDKRIQSDNKKLNSVEVNENFAHLSEYLYVAEKKAREEIRMRNNIIKQKKLKEKEQKENVLKNLAIQARKEKGFSHSSIINERKREIEREYKIEKNLKKVKNYENRYVEEQIALNKVNVSKNNNIHDISLFNINNDNTNTQDDDTYQIYDTSLFNNKTNSHIYKFSNERLKKTLQKIETRENTEPVKFIKDISDPFGLDSLLSEAKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQD7</accession>
    <name>A0A1J1GQD7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dephospho-CoA kinase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00202900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527447.1">
        <property type="nucleotide sequence ID" value="XM_028670723.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQD7"/>
    <dbReference type="GeneID" id="39730555"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00202900"/>
    <dbReference type="OMA" id="CQMDIEQ"/>
    <dbReference type="OrthoDB" id="247245at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004140">
        <property type="term" value="F:dephospho-CoA kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02022">
        <property type="entry name" value="DPCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001431">
        <property type="entry name" value="Dephospho-CoA kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00376">
        <property type="entry name" value="Dephospho_CoA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001977">
        <property type="entry name" value="Depp_CoAkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00152">
        <property type="entry name" value="dephospho-CoA kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10695:SF46">
        <property type="entry name" value="BIFUNCTIONAL COENZYME A SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10695">
        <property type="entry name" value="DEPHOSPHO-COA KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01121">
        <property type="entry name" value="CoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51219">
        <property type="entry name" value="DPCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="37"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="60"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="274" mass="31969" checksum="1876905096F95590" modified="2017-02-15" version="1">MFLITFFDKCILCFLALGSIPIGFINRKNKFKKIENNNYALFSTIIMNTFLIYINKFFGLFGIFNFFLGNYLCLIGITGGIAVGKSTFCNFLKKKNVVVINADEITNKIYKKGSTCYKKIIKHFGEDILNNDKTINRTLLRKIVFNNEENVKYINKITHTYIILQIIKECLKYKFFYFKYNVAIEAPLLIETKLYLLTSPVILLKSSVRNQIKRILSRDKNCTYDTAMSIIKNQLPTDEKIKYADIIINNDGDLLDLQMKCDVVYNKYLKSFFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQH2</accession>
    <name>A0A1J1GQH2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00215600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527574.1">
        <property type="nucleotide sequence ID" value="XM_028670863.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQH2"/>
    <dbReference type="GeneID" id="39730683"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00215600"/>
    <dbReference type="OMA" id="RVEYLPR"/>
    <dbReference type="OrthoDB" id="376398at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="393" mass="47967" checksum="3879A1C5C30C94D2" modified="2017-02-15" version="1">MKEREGKSYGKNEKIYVIYDEIYDIYIKEKKKKNCYCKILRFLNPSVLILKVLSEIYNLKDRIEYISCSSFQMVKEHTYINGEKKGIYETLLILYSINKSNLKINNNINIFNDSLIKNVDTDIIDLNMYHILNEFNDIYEYLLIIYKNCYENYTKKFFINKDYNLIKGYIKLQKFKKYVLKKYKNISFDTILNKFIKLLNLFTKLKNNYKQIECIIFYVYFYIFLNIPIYFYPWNNISDNLNKKIFKDGNVNMITNIIEKNKNNFFSCILNRTEGTSDYFETYEFNIALFINNEQEKNNEISLNQDKMMPKDLYNNLFCKNNKYFINLSEYNILKEIGYNSLKQFYIPHFYYLIILKKFLIFNKKMQIMQYLFHILTKSLIKIDEYYKNNIKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQH6</accession>
    <name>A0A1J1GQH6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein uL24c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00125000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526365.1">
        <property type="nucleotide sequence ID" value="XM_028674766.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQH6"/>
    <dbReference type="GeneID" id="39729775"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00125000"/>
    <dbReference type="OMA" id="IVDGCNM"/>
    <dbReference type="OrthoDB" id="359154at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06089">
        <property type="entry name" value="KOW_RPL26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000052">
        <property type="entry name" value="50S ribosomal protein L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01326_B">
        <property type="entry name" value="Ribosomal_uL24_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003256">
        <property type="entry name" value="Ribosomal_uL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057264">
        <property type="entry name" value="Ribosomal_uL24_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041988">
        <property type="entry name" value="Ribosomal_uL24_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01079">
        <property type="entry name" value="rplX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12903">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17136">
        <property type="entry name" value="ribosomal_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="KOW" evidence="7">
        <location>
            <begin position="55"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="230" mass="26997" checksum="56EC1CA9C7C4694A" modified="2017-02-15" version="1">MSKYVKYFVQAKKLDKRKRKYYKLEFLELNKELSIPYPLREQNQPKRLDLSKYLNIEVGDLVKVLYGPDKDKEGLVLSINPKRNTVIVDGCNMKKSAWNVTSKKGSIITQEMPIHITNVAILDPINKKPTVVKRRYMMNGECVRISKISGCAMPEPVNKNILKEQNNYELFIQKKKTGPPIKDIYAEKDSKNFNLLKKIAYEIKKKRFYEMKNFFKKDEENEKSSTIKSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQN1</accession>
    <name>A0A1J1GQN1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00222000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527638.1">
        <property type="nucleotide sequence ID" value="XM_028670935.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQN1"/>
    <dbReference type="GeneID" id="39730747"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00222000"/>
    <dbReference type="OMA" id="SQCFCER"/>
    <dbReference type="OrthoDB" id="391562at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="333"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="372"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="417"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="485"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="522" mass="61001" checksum="0CF64C5EFD981153" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQT0</accession>
    <name>A0A1J1GQT0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Geranylgeranyl transferase type-2 subunit alpha</fullName>
            <ecNumber evidence="6">2.5.1.60</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Geranylgeranyl transferase type II subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00201700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21240"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11537"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57533"/>
            <dbReference type="ChEBI" id="CHEBI:86021"/>
            <dbReference type="EC" id="2.5.1.60"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the protein prenyltransferase subunit alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.60" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527435.1">
        <property type="nucleotide sequence ID" value="XM_028670709.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQT0"/>
    <dbReference type="GeneID" id="39730543"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00201700"/>
    <dbReference type="OMA" id="WEFYRWF"/>
    <dbReference type="OrthoDB" id="1658at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005968">
        <property type="term" value="C:Rab-protein geranylgeranyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004663">
        <property type="term" value="F:Rab geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097354">
        <property type="term" value="P:prenylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.120">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002088">
        <property type="entry name" value="Prenyl_trans_a"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129:SF2">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129">
        <property type="entry name" value="PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01239">
        <property type="entry name" value="PPTA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52075">
        <property type="entry name" value="Outer arm dynein light chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48439">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51147">
        <property type="entry name" value="PFTA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 6" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6 8" id="KW-0808">Transferase</keyword>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="79"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="690" mass="84269" checksum="551B091D07A7E780" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQU7</accession>
    <name>A0A1J1GQU7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Inorganic anion exchanger, inorganic anion antiporter, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SulP</name>
        <name evidence="7" type="ORF">PGAL8A_00230700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527724.1">
        <property type="nucleotide sequence ID" value="XM_028671030.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQU7"/>
    <dbReference type="GeneID" id="39730834"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00230700"/>
    <dbReference type="OMA" id="IPETAGF"/>
    <dbReference type="OrthoDB" id="288203at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052706">
        <property type="entry name" value="Membrane-Transporter-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43310">
        <property type="entry name" value="SULFATE TRANSPORTER YBAR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43310:SF1">
        <property type="entry name" value="SULFATE TRANSPORTER YBAR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="166"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="327"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="366"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="402"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="425"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="473"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="SLC26A/SulP transporter" evidence="6">
        <location>
            <begin position="85"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG94910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="664" mass="75646" checksum="8CD3EB178A2FC000" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR66</accession>
    <name>A0A1J1GR66_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatidylinositol N-acetylglucosaminyltransferase subunit GPI1, putative</fullName>
            <ecNumber evidence="3">2.4.1.198</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">GPI1</name>
        <name evidence="3" type="ORF">PGAL8A_00147300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.198" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526589.1">
        <property type="nucleotide sequence ID" value="XM_028675016.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR66"/>
    <dbReference type="GeneID" id="39729997"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00147300"/>
    <dbReference type="OMA" id="CLNIFFP"/>
    <dbReference type="OrthoDB" id="70250at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017176">
        <property type="term" value="F:phosphatidylinositol N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007720">
        <property type="entry name" value="PigQ/GPI1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21329:SF3">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT Q"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21329">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT Q-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05024">
        <property type="entry name" value="Gpi1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="294"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="388"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="546"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="582"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="179"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="661" mass="79557" checksum="A26C9C2D342E524B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRI7</accession>
    <name>A0A1J1GRI7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein kinase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00243200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527847.1">
        <property type="nucleotide sequence ID" value="XM_028671168.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRI7"/>
    <dbReference type="GeneID" id="39730960"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00243200"/>
    <dbReference type="OMA" id="FIFSEAN"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053083">
        <property type="entry name" value="TF_kinase-domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44305:SF2">
        <property type="entry name" value="SI:DKEY-192D15.2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44305">
        <property type="entry name" value="SI:DKEY-192D15.2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="151"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="493" mass="59153" checksum="F9BEAE4FF7E5BBD2" modified="2017-02-15" version="1">MSKWGLLRSKIIWPKEFVYVIENEGYENKFGYSYIVKYNGNIVQKNLKKNLNQIKKLLNITNDISQDIEKENDQYDSDDLEYNKDAALSEIEKANQITLRLNDKKEYIEDQLSKVKTINEKFDIIIKNEPIYMFRLDCPFLNVENSSLTEYLKKEYIRENLTKKKKKKSMHDKKNEEREYKTYLYNIKIIESEETIIENREFIYCESNTESLKINTIINEGRNIQNILYEYKESCKNTCDNEEDKRENKNEEEICYEKLSILPYSDIILLKKKHYNKEINIAGFLTPFILNGNIKKIIENINQYLIYAFDSNIIYKNLSNIVRLMAYLESNNIIHGNIKPTNLFISNDGYNILIGTFVPKIKLLNFYFYVIQKKKKIPKYISPELLFYLNKKIKIVKTNKKKIKHIEKYFIKNDIFCLGLCFYYILTMKEDIINYIDAEKMFQLKVESLQNYITKPELFFLLKNMLIYNHEYRPSWSTLLNFIDTKKNEDEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRI9</accession>
    <name>A0A1J1GRI9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metacaspase 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">MCA1</name>
        <name evidence="3" type="ORF">PGAL8A_00161200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C14B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526725.1">
        <property type="nucleotide sequence ID" value="XM_028675166.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRI9"/>
    <dbReference type="GeneID" id="39730137"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00161200"/>
    <dbReference type="OMA" id="VYWKNKK"/>
    <dbReference type="OrthoDB" id="3223806at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050452">
        <property type="entry name" value="Metacaspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104:SF30">
        <property type="entry name" value="METACASPASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104">
        <property type="entry name" value="METACASPASE-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="Caspase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase C14 caspase" evidence="2">
        <location>
            <begin position="287"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="569" mass="66733" checksum="9DA5A2763EE8D686" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRJ1</accession>
    <name>A0A1J1GRJ1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GTP-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00136300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526480.1">
        <property type="nucleotide sequence ID" value="XM_028674895.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRJ1"/>
    <dbReference type="GeneID" id="39729888"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00136300"/>
    <dbReference type="OMA" id="GKGNNMQ"/>
    <dbReference type="OrthoDB" id="347018at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.210.12">
        <property type="entry name" value="GTP1/OBG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006169">
        <property type="entry name" value="GTP1_OBG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036726">
        <property type="entry name" value="GTP1_OBG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045086">
        <property type="entry name" value="OBG_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11702">
        <property type="entry name" value="DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11702:SF44">
        <property type="entry name" value="GTP-BINDING PROTEIN OBGC, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01018">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82051">
        <property type="entry name" value="Obg GTP-binding protein N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51883">
        <property type="entry name" value="OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Obg" evidence="3">
        <location>
            <begin position="88"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="215"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="48"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="554" mass="64415" checksum="3C163F07D17EA71B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRP2</accession>
    <name>A0A1J1GRP2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00166800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526781.1">
        <property type="nucleotide sequence ID" value="XM_028669984.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRP2"/>
    <dbReference type="GeneID" id="39730194"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00166800"/>
    <dbReference type="OMA" id="SFYKLYV"/>
    <dbReference type="OrthoDB" id="374723at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012859626" evidence="2">
        <location>
            <begin position="19"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="336" mass="40885" checksum="4F2F2519785C9388" modified="2017-02-15" version="1">MQSLHIIIFFNFLFIIRATYELNNPKHLKNLLTLITHKTFSHEHITNIKNKYMVVFNCPFNNKVKRTTFPCVKRDLLKNSKKLFNIWSNNLPKIHTNKKLEKEKVYTEADHIMIKYGINEKLNYFDLSSFNTYCSFYKLYMNDKFFNIKKNIFNNLKTIKKRCFIKTDHLNSDPLEEESYINIRGDKKEKLQSEKYKIHNVIGKINYFYVIFLNKILDHTFYFVFNNNEHYIIYKNEIIYPFKIPKNDNFLKSTNINYEINNFYLIEICHSLNGITYKQNINKLLKKLSNLYFNIEFVPYNFQLPPVFYHITFIIIFSLINAYFFYKIFLKYKNHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRP6</accession>
    <name>A0A1J1GRP6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">6-cysteine protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00141200</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cell surface</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526528.1">
        <property type="nucleotide sequence ID" value="XM_028674948.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRP6"/>
    <dbReference type="GeneID" id="39729936"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00141200"/>
    <dbReference type="OMA" id="IEPEECF"/>
    <dbReference type="OrthoDB" id="384332at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2860">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010884">
        <property type="entry name" value="6_CYS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038160">
        <property type="entry name" value="6_CYS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051444">
        <property type="entry name" value="Parasite_Repro/Invasion_Surf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38796">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38796:SF1">
        <property type="entry name" value="ANCHORED PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G09600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07422">
        <property type="entry name" value="s48_45"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00970">
        <property type="entry name" value="s48_45"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51701">
        <property type="entry name" value="6_CYS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012362491" evidence="9">
        <location>
            <begin position="23"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="10">
        <location>
            <begin position="23"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="10">
        <location>
            <begin position="169"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG93706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="335" mass="38557" checksum="DAA249333859B2F3" modified="2017-02-15" version="1">MILKKLFFLALSVICSFHITSAYDHVCDFNEDRPLTFPKNQKDNLSKTCKLQPSLMDKVIIKCGSNSLKYKLNPPNCLQEVYDSNTLVNKKKIHEILEGVSSIMIRNNPEVDVNDVSLRIPPNIFADKKIFCTCEHEKTIRVRRNQVESSKVIKYTGIIEIVIPTLKEKIPGCDFTKETSSLFTNGYDHTVDINDDDDNKITCKIPLKKNMLVGFKCPKDSNIKPEDCFINGYNTNGKIQNLQQTFGFTELVMDHYNNVFYAKFPDNLKKEASFFCFCSYNEKKFVTYFFFGNVNNQNITIPELPDKNLKSNISYSVKIAASIFFMYFVSFLITL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS90</accession>
    <name>A0A1J1GS90_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF6827 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00257700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527985.1">
        <property type="nucleotide sequence ID" value="XM_028671321.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS90"/>
    <dbReference type="GeneID" id="39731105"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00257700"/>
    <dbReference type="OMA" id="HMHDFFF"/>
    <dbReference type="OrthoDB" id="361874at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049230">
        <property type="entry name" value="DUF6827"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20715">
        <property type="entry name" value="DUF6827"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6827" evidence="1">
        <location>
            <begin position="59"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="215" mass="25791" checksum="E06E7FDE082E01B3" modified="2017-02-15" version="1">MRLSSYFLYGKNFLKVFNKENGLICGTFLSNRAKNNEIKKIMLKDKRKYFTSLYNNLNEKKNIIREIDDLYDNIITSNWNDSFNLVLNVSIWEGILNSIEEKIKGYEYDNEVMKKKKEINELFDVLFILEDLRDHINEILEQSSRSSGLAGTHILSSFKIENINEHINFLKKKYEDLLLTYPSYNYQIKLVLGRGLALLRQRYNFEWKYMHEFFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSB1</accession>
    <name>A0A1J1GSB1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosome-recycling factor, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RRF1</name>
        <name evidence="6" type="ORF">PGAL8A_00016400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RRF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528206.1">
        <property type="nucleotide sequence ID" value="XM_028671567.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSB1"/>
    <dbReference type="GeneID" id="39728686"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00016400"/>
    <dbReference type="OMA" id="INHICHI"/>
    <dbReference type="OrthoDB" id="372654at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.20">
        <property type="entry name" value="Ribosome-recycling factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002661">
        <property type="entry name" value="Ribosome_recyc_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023584">
        <property type="entry name" value="Ribosome_recyc_fac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036191">
        <property type="entry name" value="RRF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982:SF3">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME RECYCLING FACTOR PSEUDO 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982">
        <property type="entry name" value="RIBOSOME RECYCLING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01765">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55194">
        <property type="entry name" value="Ribosome recycling factor, RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosome recycling factor" evidence="5">
        <location>
            <begin position="251"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="158"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="165"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="196"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="399" mass="48600" checksum="CFB4D0918EB8EFE2" modified="2017-02-15" version="1">MIIQNEKKIRKIILFYFLIFFLNKFIVIYSCLDIKKKIKYDIFLTNKNKYSSCFLNFYLYKKNILKNFRKVIYNNKFSNIKTKKNIYILYAHKKKKKQDKIEEILKKKLLNNNEKNTTEEDETINNSNEEIVIDNQIKGNDSFSLKNYKIKKNLREDIDDNEDNSTSKDKKEIKNNDNENNDNENNNLGENSVERNEDEEEEEDEEEDEEEEEDEEEYENTEEYINNLNKICLDKMNNVYKYIRKESYRFNLNNVSNIMFENEKVKINERIYTIKHICHIKKKENLFIITPYDPYYVNFIYKHFVKEYNELKFYIKDKSVFAIIPPISESLKNEIKTKIKNKIEDSKLTLRNVRKKMMDKLEKIKNKIGKDIYFKQKNYIQSIHDQTKKNIEKIFEELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSG7</accession>
    <name>A0A1J1GSG7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">indole-3-glycerol-phosphate synthase</fullName>
            <ecNumber evidence="3">4.1.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00170200</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H(+) = (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:23476"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="EC" id="4.1.1.48"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.48" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG93995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526816.1">
        <property type="nucleotide sequence ID" value="XM_028670023.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSG7"/>
    <dbReference type="GeneID" id="39730229"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00170200"/>
    <dbReference type="OMA" id="VIIHPIQ"/>
    <dbReference type="OrthoDB" id="524799at2759"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00043"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004425">
        <property type="term" value="F:indole-3-glycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004640">
        <property type="term" value="F:phosphoribosylanthranilate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:L-tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045186">
        <property type="entry name" value="Indole-3-glycerol_P_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013798">
        <property type="entry name" value="Indole-3-glycerol_P_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22854:SF2">
        <property type="entry name" value="INDOLE-3-GLYCEROL-PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22854">
        <property type="entry name" value="TRYPTOPHAN BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00218">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012339657" description="indole-3-glycerol-phosphate synthase" evidence="11">
        <location>
            <begin position="18"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="domain" description="Indole-3-glycerol phosphate synthase" evidence="12">
        <location>
            <begin position="194"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="456"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="630"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="516"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="633"/>
            <end position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG93995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="654" mass="77482" checksum="9ECE7258D0F02C55" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSU0</accession>
    <name>A0A1J1GSU0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">carnosine N-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00008700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carnosine N-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.22" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528131.1">
        <property type="nucleotide sequence ID" value="XM_028671483.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSU0"/>
    <dbReference type="GeneID" id="39728609"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00008700"/>
    <dbReference type="OMA" id="SMCAGEL"/>
    <dbReference type="OrthoDB" id="978at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030735">
        <property type="term" value="F:carnosine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012901">
        <property type="entry name" value="CARME"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12303">
        <property type="entry name" value="CARNOSINE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12303:SF6">
        <property type="entry name" value="CARNOSINE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07942">
        <property type="entry name" value="CARME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01296">
        <property type="entry name" value="N2227"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="308"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="364"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="329"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="373"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="789" mass="93533" checksum="AAB881A0C51A5A37" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSV0</accession>
    <name>A0A1J1GSV0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Phd finger protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00009500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528139.1">
        <property type="nucleotide sequence ID" value="XM_028671492.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728617"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00009500"/>
    <dbReference type="OMA" id="DVDHKMV"/>
    <dbReference type="OrthoDB" id="9547406at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15571">
        <property type="entry name" value="ePHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15489">
        <property type="entry name" value="PHD_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13831">
        <property type="entry name" value="PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13771">
        <property type="entry name" value="zf-HC5HC2H"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13832">
        <property type="entry name" value="zf-HC5HC2H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Zinc finger PHD-type" evidence="6">
        <location>
            <begin position="133"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="Zinc finger PHD-type" evidence="6">
        <location>
            <begin position="636"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="domain" description="Zinc finger PHD-type" evidence="6">
        <location>
            <begin position="2816"/>
            <end position="2863"/>
        </location>
    </feature>
    <feature type="domain" description="Zinc finger PHD-type" evidence="6">
        <location>
            <begin position="3870"/>
            <end position="3925"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1493"/>
            <end position="1539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="4546"/>
            <end position="4599"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1249"/>
            <end position="1289"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="3551"/>
            <end position="3578"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="4796"/>
            <end position="4843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1493"/>
            <end position="1530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="4556"/>
            <end position="4578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="4975" mass="596065" checksum="6D37C3E064FE73FA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT07</accession>
    <name>A0A1J1GT07_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="17">DNA repair protein RAD2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">RAD2</name>
        <name evidence="17" type="ORF">PGAL8A_00018300</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the XPG/RAD2 endonuclease family. GEN subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528225.1">
        <property type="nucleotide sequence ID" value="XM_028671587.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728705"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00018300"/>
    <dbReference type="OMA" id="AKDDMDI"/>
    <dbReference type="OrthoDB" id="31113at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048256">
        <property type="term" value="F:flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09904">
        <property type="entry name" value="H3TH_XPG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09868">
        <property type="entry name" value="PIN_XPG_RAD2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000030">
        <property type="entry name" value="Flap endonuclease GEN-like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006086">
        <property type="entry name" value="XPG-I_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019974">
        <property type="entry name" value="XPG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006085">
        <property type="entry name" value="XPG_DNA_repair_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16171">
        <property type="entry name" value="DNA REPAIR PROTEIN COMPLEMENTING XP-G CELLS-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16171:SF7">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00867">
        <property type="entry name" value="XPG_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00752">
        <property type="entry name" value="XPG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00853">
        <property type="entry name" value="XPGRADSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00484">
        <property type="entry name" value="XPGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00485">
        <property type="entry name" value="XPGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69349">
        <property type="entry name" value="Phage fibre proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00841">
        <property type="entry name" value="XPG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XPG N-terminal" evidence="16">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="XPG-I" evidence="15">
        <location>
            <begin position="1315"/>
            <end position="1384"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="617"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="1241"/>
            <end position="1305"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="1543"/>
            <end position="1570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="CRG95414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1610" mass="191565" checksum="1C036BC9FDCE42A9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT12</accession>
    <name>A0A1J1GT12_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MORN repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00019100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528233.1">
        <property type="nucleotide sequence ID" value="XM_028671596.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT12"/>
    <dbReference type="GeneID" id="39728713"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00019100"/>
    <dbReference type="OMA" id="DIYQGQY"/>
    <dbReference type="OrthoDB" id="270720at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43215">
        <property type="entry name" value="RADIAL SPOKE HEAD 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43215:SF14">
        <property type="entry name" value="RADIAL SPOKE HEAD 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="198" mass="23490" checksum="F4A7EDBE6D7F32B1" modified="2017-02-15" version="1">MIEFLGEKEVCKSFERNYSGEANVKYKNGDKFVGTFENGEKKKGKYYYSNKSIYEGFYLNGKKSGLGKLIKSENEFYYGNFENGKKKGIGFQKYPNGDFYYGEWINNKKNGKGIYYFYSTKEYYFGEWCKGNFISGEWQISNELKYIGKYFKNKPKCVGYFLFSNELKINVFFKQLLSISNINKNKEENIELKWNYIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT15</accession>
    <name>A0A1J1GT15_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dynein light chain, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00019900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528241.1">
        <property type="nucleotide sequence ID" value="XM_028671605.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT15"/>
    <dbReference type="GeneID" id="39728721"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00019900"/>
    <dbReference type="OMA" id="FGAGWIC"/>
    <dbReference type="OrthoDB" id="6506078at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21453">
        <property type="entry name" value="DLC-like_DNAL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.740.10:FF:000007">
        <property type="entry name" value="Dynein light chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.740.10">
        <property type="entry name" value="Protein Inhibitor Of Neuronal Nitric Oxide Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037177">
        <property type="entry name" value="DLC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001372">
        <property type="entry name" value="Dynein_light_chain_typ-1/2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01221">
        <property type="entry name" value="Dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01375">
        <property type="entry name" value="Dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54648">
        <property type="entry name" value="DLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="107" mass="12358" checksum="AF42998A69A463E9" modified="2017-02-15" version="1">MNSQNFYQNLKKHMQSLLIRKSDIPYYNQNNIVDIITGVLDKFTNANTNVINVENAIKNIKEILDKNFGVGWICIIGESFSFNISAKENSFLFCFYQGYLAIVVYKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT27</accession>
    <name>A0A1J1GT27_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00283100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528442.1">
        <property type="nucleotide sequence ID" value="XM_028671828.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT27"/>
    <dbReference type="GeneID" id="39731364"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00283100"/>
    <dbReference type="OMA" id="EYDKYQD"/>
    <dbReference type="OrthoDB" id="372916at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050781">
        <property type="entry name" value="CWC22_splicing_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003891">
        <property type="entry name" value="Initiation_fac_eIF4g_MI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18034">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN CWF22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18034:SF4">
        <property type="entry name" value="NUCLEOLAR MIF4G DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51366">
        <property type="entry name" value="MI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MI" evidence="6">
        <location>
            <begin position="681"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="194"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="86"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="14"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="51"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="207"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="893" mass="106358" checksum="DE4ECD3744805728" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT78</accession>
    <name>A0A1J1GT78_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00190500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000027">
        <property type="protein sequence ID" value="CRG94508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527325.1">
        <property type="nucleotide sequence ID" value="XM_028670587.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT78"/>
    <dbReference type="GeneID" id="39730430"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00190500"/>
    <dbReference type="OMA" id="YNNMYDD"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="747"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="941" mass="116457" checksum="202FD4BC180C5133" modified="2017-02-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT92</accession>
    <name>A0A1J1GT92_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00265100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000034">
        <property type="protein sequence ID" value="CRG95448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528259.1">
        <property type="nucleotide sequence ID" value="XM_028671625.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT92"/>
    <dbReference type="GeneID" id="39731180"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00265100"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="294"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="330" mass="39114" checksum="E47C98566610DDCE" modified="2017-02-15" version="1">MALLYNKGCDDFEGNSAKCHMTICPIDKSKYETSYCQVQLNPIKVYRPLYNVSNDISQNMFKYIRYGPYEFSRIIILSNNNQDGIVFLYELNPYKDDFPFKTYLCRLKNINQRITLCESIDINYLGKNLSFNSYDVINGKNNLSSLKLLKNPRHKIIKAKYKNLFYKQHFCHVVKTKFVTHLRCVNYLCEKYNEEYTLCTNANYSGKLVFLDYYSYQRNIKDLIYLPDSCLKKDSNFACTPYFCQKKVINQFTSCEYQEISAIKNIAISPKSLDVISTNPQNVYHENNMSAPELFAIAFVPFLILFVFFWCYIYKLMKKRRRKFYNAKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTD3</accession>
    <name>A0A1J1GTD3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Circumsporozoite-and TRAP-related protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CTRP</name>
        <name evidence="8" type="ORF">PGAL8A_00401100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527128.1">
        <property type="nucleotide sequence ID" value="XM_028670369.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732541"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00401100"/>
    <dbReference type="OMA" id="DALCNEW"/>
    <dbReference type="OrthoDB" id="446173at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd01473">
        <property type="entry name" value="vWA_CTRP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="CDD" id="cd00198">
        <property type="entry name" value="vWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.100.10:FF:000105">
        <property type="entry name" value="Circumsporozoite-and TRAP-related protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.100.10">
        <property type="entry name" value="Thrombospondin type-1 (TSP1) repeat"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050525">
        <property type="entry name" value="ECM_Assembly_Org"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000884">
        <property type="entry name" value="TSP1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036383">
        <property type="entry name" value="TSP1_rpt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24020">
        <property type="entry name" value="COLLAGEN ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00090">
        <property type="entry name" value="TSP_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00209">
        <property type="entry name" value="TSP1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82895">
        <property type="entry name" value="TSP-1 type 1 repeat"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50092">
        <property type="entry name" value="TSP1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012158941" evidence="6">
        <location>
            <begin position="24"/>
            <end position="1883"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1818"/>
            <end position="1839"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="7">
        <location>
            <begin position="79"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="7">
        <location>
            <begin position="294"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="7">
        <location>
            <begin position="517"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="7">
        <location>
            <begin position="732"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="7">
        <location>
            <begin position="945"/>
            <end position="1131"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="7">
        <location>
            <begin position="1170"/>
            <end position="1352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1790"/>
            <end position="1810"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="573"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1798"/>
            <end position="1808"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1883" mass="213997" checksum="7BEF609236FBE49D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTE2</accession>
    <name>A0A1J1GTE2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00269850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000039">
        <property type="protein sequence ID" value="CRG95498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528307.1">
        <property type="nucleotide sequence ID" value="XM_028671679.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTE2"/>
    <dbReference type="GeneID" id="39731230"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00269850"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="138" mass="16665" checksum="0668E05F7A357F58" modified="2017-02-15" version="1">MKTFTLRLKIFTFLLLIWIFHCFYSYDSIRSLIYKDTLQIKNRLKDGRMLAEGGMLKKKQTCIKEHSEHYLYDEKDNKEDKLVYLKNMYNIWYNVIILSMCELLSIKKNEMANKCRDKLLNVHRNNTYEFSIPALSMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTF2</accession>
    <name>A0A1J1GTF2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00293200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528535.1">
        <property type="nucleotide sequence ID" value="XM_028671931.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTF2"/>
    <dbReference type="GeneID" id="39731465"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00293200"/>
    <dbReference type="OMA" id="TIECMFE"/>
    <dbReference type="OrthoDB" id="384377at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="708"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="260"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="856" mass="105367" checksum="E1EB3DE8247FAC6A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTN0</accession>
    <name>A0A1J1GTN0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">diphosphoinositol-pentakisphosphate 1-kinase</fullName>
            <ecNumber evidence="3">2.7.4.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PGAL8A_00301900</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>1D-myo-inositol hexakisphosphate + ATP = 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:37459"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58130"/>
            <dbReference type="ChEBI" id="CHEBI:74946"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:37460"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + ATP + H(+) = 1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:10276"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58628"/>
            <dbReference type="ChEBI" id="CHEBI:77983"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.24"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:10277"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histidine acid phosphatase family. VIP1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.24" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528615.1">
        <property type="nucleotide sequence ID" value="XM_028672020.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731552"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00301900"/>
    <dbReference type="OrthoDB" id="18042at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033857">
        <property type="term" value="F:5-diphosphoinositol pentakisphosphate 1-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000828">
        <property type="term" value="F:inositol hexakisphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006020">
        <property type="term" value="P:inositol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032958">
        <property type="term" value="P:inositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000050">
        <property type="entry name" value="Acid phosphatase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11950:FF:000002">
        <property type="entry name" value="Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1240:FF:000062">
        <property type="entry name" value="Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033379">
        <property type="entry name" value="Acid_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037446">
        <property type="entry name" value="His_Pase_VIP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040557">
        <property type="entry name" value="VIP1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12750">
        <property type="entry name" value="DIPHOSPHOINOSITOL PENTAKISPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12750:SF9">
        <property type="entry name" value="INOSITOL HEXAKISPHOSPHATE AND DIPHOSPHOINOSITOL-PENTAKISPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18086">
        <property type="entry name" value="PPIP5K2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00616">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="VIP1 N-terminal" evidence="13">
        <location>
            <begin position="31"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="466"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1392"/>
            <end position="1455"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="1890"/>
            <end position="1917"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="466"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="485"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="536"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1392"/>
            <end position="1433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="1434"/>
            <end position="1451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00034629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF18086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG95807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2033" mass="238130" checksum="09184EE668C1A241" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTV3</accession>
    <name>A0A1J1GTV3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Probable cytosolic iron-sulfur protein assembly protein CIAO1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CIA1</name>
        <name evidence="6" type="ORF">PGAL8A_00312700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat CIA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528722.1">
        <property type="nucleotide sequence ID" value="XM_028672139.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTV3"/>
    <dbReference type="GeneID" id="39731660"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00312700"/>
    <dbReference type="OrthoDB" id="284782at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097361">
        <property type="term" value="C:cytosolic [4Fe-4S] assembly targeting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03037">
        <property type="entry name" value="ciao1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028608">
        <property type="entry name" value="CIAO1/Cia1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19920:SF0">
        <property type="entry name" value="CYTOSOLIC IRON-SULFUR PROTEIN ASSEMBLY PROTEIN CIAO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19920">
        <property type="entry name" value="WD40 PROTEIN CIAO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="9"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="128"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="208"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="253"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="440"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="440"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="626" mass="74323" checksum="4B3E198A4C4E236A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU58</accession>
    <name>A0A1J1GU58_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">ATP-dependent zinc metalloprotease FTSH, putative</fullName>
            <ecNumber evidence="13">3.4.24.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00224300</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the peptidase M41 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the N-terminal section; belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="13"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527661.1">
        <property type="nucleotide sequence ID" value="XM_028670960.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU58"/>
    <dbReference type="GeneID" id="39730770"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00224300"/>
    <dbReference type="OMA" id="KYDSDPM"/>
    <dbReference type="OrthoDB" id="1413014at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19501">
        <property type="entry name" value="RecA-like_FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000001">
        <property type="entry name" value="ATP-dependent zinc metalloprotease FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.760:FF:000008">
        <property type="entry name" value="ATP-dependent zinc metalloprotease FTSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000195">
        <property type="entry name" value="ATP-dependent zinc metalloprotease FTSH 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="entry name" value="Peptidase M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076:SF97">
        <property type="entry name" value="ATP-DEPENDENT ZINC METALLOPROTEASE YME1L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076">
        <property type="entry name" value="METALLOPROTEASE M41 FTSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="FtsH protease domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 13" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="12">
        <location>
            <begin position="281"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="136"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG94846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="701" mass="79615" checksum="2BC734DC6C8FD848" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUA3</accession>
    <name>A0A1J1GUA3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00325200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000053">
        <property type="protein sequence ID" value="CRG96039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528847.1">
        <property type="nucleotide sequence ID" value="XM_028672279.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUA3"/>
    <dbReference type="GeneID" id="39731785"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00325200"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="296"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="334" mass="39006" checksum="ECC1A95E49227D72" modified="2017-02-15" version="1">MALLYNEGCENSEKDITECNVTACVLHGSKFKSVKCDPAFKEVIKYSQKNSGDDIKKNIFVFEDTPPPYKNDAKITFLSQDSNNDIVFLYEVNSKEGYSSSLVFLCRFRHLKPGLSLCQEVNKDHVGRPLSFNTIDVLDRENENYFQNRLKYLKNERHATRKARYEEIFFSKDSCHYVTEENSSEQVCRFSICKKYSNGGAYCKDAKFNGRLCQLEPSNGPKEPTKFIYLPNSCLNENSDHCTPYLCQYERPNELYPCSKLEISSVKGLMPHSQRQALEYRQNRYMSNEDNYSSSLIAMSFFPFLILFFFVGCYLYKVLRRNRKKKRYASYKEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUN2</accession>
    <name>A0A1J1GUN2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Replication factor C subunit 5, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">RFC5</name>
        <name evidence="2" type="ORF">PGAL8A_00338000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528967.1">
        <property type="nucleotide sequence ID" value="XM_028672412.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUN2"/>
    <dbReference type="GeneID" id="39731910"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00338000"/>
    <dbReference type="OrthoDB" id="761538at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005663">
        <property type="term" value="C:DNA replication factor C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001654">
        <property type="entry name" value="Replication factor C subunit 5, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050238">
        <property type="entry name" value="DNA_Rep/Repair_Clamp_Loader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669">
        <property type="entry name" value="REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669:SF1">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13177">
        <property type="entry name" value="DNA_pol3_delta2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="349" mass="40329" checksum="6DC1269B9B227026" modified="2017-02-15" version="1">MWLEKYAPQSLDELTIHKDITERLKKLSAHKDLPHIIFYGTPGGGKSTRIDCLIKEIFKEEKIIRRPECITNVENKININVVQSNYHLELQCFELGSKDKIIVQSIIKELCSYKSSASFFSKTPMYRIFVFKDAEFLSEGAQAGLRRTLETYIRNARVILHLEHLSKIIEPLKSRCICIRVPLPTEEEIFSVLKNICDNENVSESFSSQSFFKNLIETHGRNLRKCIMALEMTVYANSTKPHQSLSVAATYINELCDFVFINPTQTKMKECVTKIQSLITCQIPVNFIFETTIKYLLRSNYDYKLKCYFLKLCSHFSYLSEASYDKSVSLIAFIVNVNTAIVKYNLSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUQ5</accession>
    <name>A0A1J1GUQ5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">GTP binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00340400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528991.1">
        <property type="nucleotide sequence ID" value="XM_028672439.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUQ5"/>
    <dbReference type="GeneID" id="39731934"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00340400"/>
    <dbReference type="OMA" id="VCHPYRE"/>
    <dbReference type="OrthoDB" id="10268034at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11060">
        <property type="entry name" value="GTPase HflX, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030394">
        <property type="entry name" value="G_HFLX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016496">
        <property type="entry name" value="GTPase_HflX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025121">
        <property type="entry name" value="GTPase_HflX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042108">
        <property type="entry name" value="GTPase_HflX_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10229:SF0">
        <property type="entry name" value="GTP-BINDING PROTEIN 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10229">
        <property type="entry name" value="GTP-BINDING PROTEIN HFLX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13167">
        <property type="entry name" value="GTP-bdg_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51705">
        <property type="entry name" value="G_HFLX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hflx-type G" evidence="5">
        <location>
            <begin position="504"/>
            <end position="674"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="735" mass="86853" checksum="572E941FE4A4BAE5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUZ0</accession>
    <name>A0A1J1GUZ0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00351900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529106.1">
        <property type="nucleotide sequence ID" value="XM_028672567.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUZ0"/>
    <dbReference type="GeneID" id="39732049"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00351900"/>
    <dbReference type="OMA" id="LLWMYRY"/>
    <dbReference type="OrthoDB" id="376266at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="6"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="244" mass="29059" checksum="AD26041D56DC5B4A" modified="2017-02-15" version="1">MVTKLIKFIILRPRGIPQNLELEINCNEIIKNLKQKLFPEDIKKDLNVRLIYMGKILDDKKKLEDYLNFYQKELLINNKKDNYFINEKKNENQNEINKDINNQNISRSYKENIPITIHVKITEKSTSAKNANNEGKGINTSLAQISLVAFVLLLWLYRYNYSSIFPLFSTTVLFLFTILIMTIIFHSYLVLFFNIAFKVITTIYQIIKYYFVRIYTYIIQKKEKLCIKKKLKNDENDEKNLKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV21</accession>
    <name>A0A1J1GV21_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Shewanella-like protein phosphatase 1, putative</fullName>
            <ecNumber evidence="2">3.1.3.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">SHLP1</name>
        <name evidence="2" type="ORF">PGAL8A_00228600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527704.1">
        <property type="nucleotide sequence ID" value="XM_028671008.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV21"/>
    <dbReference type="GeneID" id="39730813"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00228600"/>
    <dbReference type="OMA" id="DENDEWC"/>
    <dbReference type="OrthoDB" id="5976022at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46546">
        <property type="entry name" value="SHEWANELLA-LIKE PROTEIN PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46546:SF4">
        <property type="entry name" value="SHEWANELLA-LIKE PROTEIN PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="1">
        <location>
            <begin position="59"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="358" mass="42255" checksum="1193CA6C5C6D1FD0" modified="2017-02-15" version="1">MIIDEKICILLLIYILIVKEINSSIYLKDNFLFKNLVINKKNLDSSYFYNYDNLKWDGKIVAIGDIHGDIEGLKLILKHSNLIDENDEWCGENVLLIQVGDILDRGIYGPLIYDYLFDLQKKAVIKNSKIILILGNHEQLNLCGYYNYVNEKETQLFFENNYNYRSFSFNNKNGNYFKKLIKLPSIVKVNNAIFTHAGISKKMSQFSINLINLKIRLQIENKCKILKYDNYNYLNHDSVLWYDDFSYKVRLNHHEGCSELFQILKKYNSSYLVVGHTKQVSHKIGSFCDNKYFLIDTGMSLFMNNGISHPSYLLIEQNKFKSIHLFIEYRNKKKCSREIHLHNPYNKKLCIYSKQIDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV34</accession>
    <name>A0A1J1GV34_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00256500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527973.1">
        <property type="nucleotide sequence ID" value="XM_028671307.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731093"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00256500"/>
    <dbReference type="OMA" id="RIYAENY"/>
    <dbReference type="OrthoDB" id="392888at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="58"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="948"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="537"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="70"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="110"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="121"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="137"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="179"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="232"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1314" mass="156613" checksum="9047DFB5AEE1EA30" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV47</accession>
    <name>A0A1J1GV47_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00231100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527728.1">
        <property type="nucleotide sequence ID" value="XM_028671035.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV47"/>
    <dbReference type="GeneID" id="39730838"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00231100"/>
    <dbReference type="OMA" id="VIEVYSE"/>
    <dbReference type="OrthoDB" id="377447at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="421"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="425"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="460"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="472"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="493"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1199" mass="139849" checksum="41D7A5BFAE8BF80D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV63</accession>
    <name>A0A1J1GV63_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">26S protease regulatory subunit 6a, putative</fullName>
            <ecNumber evidence="12">3.6.4.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">RPT5</name>
        <name evidence="12" type="ORF">PGAL8A_00357800</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.8" evidence="12"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529159.1">
        <property type="nucleotide sequence ID" value="XM_028672625.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV63"/>
    <dbReference type="GeneID" id="39732108"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00357800"/>
    <dbReference type="OMA" id="NKISHEH"/>
    <dbReference type="OrthoDB" id="9443236at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000009">
        <property type="entry name" value="26S protease regulatory subunit 6A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000037">
        <property type="entry name" value="26S protease regulatory subunit 6A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000183">
        <property type="entry name" value="26S protease regulatory subunit 6a, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032501">
        <property type="entry name" value="Prot_ATP_ID_OB_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16450">
        <property type="entry name" value="Prot_ATP_ID_OB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-0647">Proteasome</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="11">
        <location>
            <begin position="219"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="29"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG96354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="439" mass="49612" checksum="A0AD5B8CE6A1A405" modified="2017-02-15" version="1">MNVENIFGNEEVNVDEIEKLSNNEIKTRISLIDTEVKILKNEHARLKNEYKNLQEKIKDNLEKIHLNKMLPYLVANVVESLDLEDEEEENEPKDEYDLYDNNMKLSHEGFRDIDDEKRGKCMVIKTSTRQTIFLPVPGLIEASELRPGDLVGVNKDSYLIIDKLPQEYDNRVKAMEVIEKPSEDYSDIGGLDKQIEDLVEAIVLPMLHKEKFEKIGIKPPKGVLMHGPPGTGKTLLARACASQTNATFLKLAGPQLVQMFIGDGAKMVRDAFNLAKEKAPAIIFIDELDAIGTKRFDSELSGDREVQRTMLELLNQLDGFSTDDTVKVIAATNRPDTLDPALLRSGRLDRKIELPHPNEESRARILQIHSRKMNVHKDVNFEELARSTDDFNGAQLKAVCVEAGMIALRRGATEIDHEDFVEGITSVLSKKKSTLNYFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV68</accession>
    <name>A0A1J1GV68_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RNA (Uracil-5-)methyltransferase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00361300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529194.1">
        <property type="nucleotide sequence ID" value="XM_028672664.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV68"/>
    <dbReference type="GeneID" id="39732143"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00361300"/>
    <dbReference type="OMA" id="NLRNKWE"/>
    <dbReference type="OrthoDB" id="10250660at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009451">
        <property type="term" value="P:RNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030390">
        <property type="entry name" value="MeTrfase_TrmA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030391">
        <property type="entry name" value="MeTrfase_TrmA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045850">
        <property type="entry name" value="TRM2_met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010280">
        <property type="entry name" value="U5_MeTrfase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45904">
        <property type="entry name" value="TRNA (URACIL-5-)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45904:SF2">
        <property type="entry name" value="TRNA (URACIL-5-)-METHYLTRANSFERASE HOMOLOG A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05958">
        <property type="entry name" value="tRNA_U5-meth_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51687">
        <property type="entry name" value="SAM_MT_RNA_M5U"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01230">
        <property type="entry name" value="TRMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01231">
        <property type="entry name" value="TRMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="5">
        <location>
            <position position="670"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="670"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="536"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="591"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="642"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="715" mass="83881" checksum="59611E37D7FD3030" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVH5</accession>
    <name>A0A1J1GVH5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Activator of Hsp90 ATPase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">AHA1</name>
        <name evidence="4" type="ORF">PGAL8A_00005500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AHA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528101.1">
        <property type="nucleotide sequence ID" value="XM_028671450.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVH5"/>
    <dbReference type="GeneID" id="39728577"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00005500"/>
    <dbReference type="OMA" id="EDNDYEI"/>
    <dbReference type="OrthoDB" id="567237at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001671">
        <property type="term" value="F:ATPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.15.10.20">
        <property type="entry name" value="Activator of Hsp90 ATPase Aha1, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036338">
        <property type="entry name" value="Aha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015310">
        <property type="entry name" value="AHSA1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13009">
        <property type="entry name" value="HEAT SHOCK PROTEIN 90 HSP90 CO-CHAPERONE AHA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13009:SF22">
        <property type="entry name" value="LD43819P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09229">
        <property type="entry name" value="Aha1_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01000">
        <property type="entry name" value="Aha1_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103111">
        <property type="entry name" value="Activator of Hsp90 ATPase, Aha1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Activator of Hsp90 ATPase AHSA1-like N-terminal" evidence="3">
        <location>
            <begin position="15"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Activator of Hsp90 ATPase AHSA1-like N-terminal" evidence="3">
        <location>
            <begin position="208"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="158"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="346" mass="41037" checksum="8FA568680E51AD0B" modified="2017-02-15" version="1">MAGSVWNRNSWHWEEKNYNKWGESYIKSKLINLKIEKDNLTIYFDNIDISGNTCVSIRKGKQISSFEYIIKFRWLSSMKTDSKEHSGNIEILDFSNCSLEDNDYEINIEKDSDNEKSRKIYDILKKEGKQKIKDTLKNFPEDLLKHDKNESSKELMIKQAEEEKLKNIEILNRDEKKNENLIENLNKDINCEKKEGSIWNINNYHWEEKCLTKWAKEELKNTLENSSIELSNNIFLQFFYSEVEGEASSSLRKKKKILIYDLKINSEWKAYKKNKNNEIEIETKGHISINEIISDFSCDDENKYKYSFIFDNNTPEHKNINDVVKSEGPNEINKIIDLFISKMKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVK2</accession>
    <name>A0A1J1GVK2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DEAD/DEAH box helicase, putative</fullName>
            <ecNumber evidence="6">3.6.4.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00415900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529382.1">
        <property type="nucleotide sequence ID" value="XM_028672873.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732690"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00415900"/>
    <dbReference type="OrthoDB" id="64767at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052431">
        <property type="entry name" value="SKI2_subfamily_helicases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44533">
        <property type="entry name" value="DEAD/H RNA HELICASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44533:SF4">
        <property type="entry name" value="DEAD_H RNA HELICASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 6" id="KW-0347">Helicase</keyword>
    <keyword evidence="1 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="1140"/>
            <end position="1322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="579"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="807"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1028"/>
            <end position="1070"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="332"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="586"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="807"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="821"/>
            <end position="830"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2412" mass="287761" checksum="4AD28DCE1D761A2F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVN7</accession>
    <name>A0A1J1GVN7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Telomere length regulation protein conserved domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00419800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529422.1">
        <property type="nucleotide sequence ID" value="XM_028672917.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732730"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00419800"/>
    <dbReference type="OrthoDB" id="371666at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="782"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="510"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="790"/>
            <end position="906"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1480" mass="178151" checksum="CE85D1D78DD8461D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVY6</accession>
    <name>A0A1J1GVY6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00258400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527992.1">
        <property type="nucleotide sequence ID" value="XM_028671329.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVY6"/>
    <dbReference type="GeneID" id="39731113"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00258400"/>
    <dbReference type="OMA" id="FIFCLRM"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="130" mass="15722" checksum="BF45E15B1D33E090" modified="2017-02-15" version="1">MKEEINLGLKDYNLERDTDGNKEKIKDKKNKKAENFGLNDILYYKENFKVLKKFFIFVLLIILSPVILIVLYNYFFKIFFKLSKNDSLLYSLYFVIFYILFLTFLYAYLAFKEDNNTTNNNTIKEEKKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW08</accession>
    <name>A0A1J1GW08_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DnaJ protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00431900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529542.1">
        <property type="nucleotide sequence ID" value="XM_028673050.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW08"/>
    <dbReference type="GeneID" id="39732851"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00431900"/>
    <dbReference type="OMA" id="TLIYLMR"/>
    <dbReference type="OrthoDB" id="66964at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43096:SF10">
        <property type="entry name" value="CHAPERONE PROTEIN DNAJ A6, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43096">
        <property type="entry name" value="DNAJ HOMOLOG 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="5"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="358"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="53"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="381" mass="44704" checksum="C252256FA90EBA60" modified="2017-02-15" version="1">MLNDIIFQVIIAAFGVSLVNSDKLKFLHKLKYAIYILILSFLLYKGIPWKRENYYTYLSVTPNATKQEIQTAYRQAAKVYHPDKNPDEYADSSFIKLKLAYDILTDDVRRSNYNRFGDYKNGEVDDNTATLLICLSLVQHTMFFIIGYFLSYPKKLEFSRQIFLVYNIASFCFELQFRFIEDDTTFDWLPFLGYLLPYEKIKLLRMLFPIVFFISICASAHIYTDKNATMIFLMRSILSTNRIIVERSNDVIESTNYLKKHGTDIISKLQHIRKNELSSTLNLKDASKIGNENLENVNKYDTENSGKKSSKDEVIDSKLLDNIQKFSLTLDSQQMNLLEKCFELMKNKSSKDKNKKKSWFEFFSLQMIFGIIFVYIWLTSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW35</accession>
    <name>A0A1J1GW35_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00263300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528040.1">
        <property type="nucleotide sequence ID" value="XM_028671382.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW35"/>
    <dbReference type="GeneID" id="39731162"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00263300"/>
    <dbReference type="OMA" id="GKWLIEV"/>
    <dbReference type="OrthoDB" id="189968at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045943">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19924:SF26">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19924">
        <property type="entry name" value="UTP15 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 15 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="110"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="464" mass="54900" checksum="464744FE976273FD" modified="2017-02-15" version="1">MSFFQPVELIRKRKKINETNDYLFDFKILKTRDENASIKSISICSKYVAISYNNTIILNNIKGESLDKKYQCKENVSKLKFRDDKMLGVGLENGDIELIGMFCFDRIKKLEGHKSTINDLIFSANFQNLYSCSRDFTIKIWNIWKGICEYSLDYHIDNVTSICLYNFDNNINYLISSSYDGYVYLYDLSLNKCLNKLELIEPVDYLYIFKNEYLVLSIKNIIKIYNLENLEFIKDIIVSTKTIFYINIFKNFLVAASLDKSIYFIDPFHKNLQNIKIVSIANFIKSPKSIDVFNDILVLGELEGSWFIEVYNEKEKNKKAKNQHNNSINNFEMERYVYTDNKINNLVKKFKYRDALMNIINNDPQSTLSLLDYFSKHKVLVAACRTYSIQEALKILTFFRKKFVIDILMFEFFFSFFSANKWIITTKNTKVLEELQLLKREFENVKNSMKYYHSLKEIADNLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWL7</accession>
    <name>A0A1J1GWL7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00289800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528509.1">
        <property type="nucleotide sequence ID" value="XM_028671903.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWL7"/>
    <dbReference type="GeneID" id="39731431"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00289800"/>
    <dbReference type="OMA" id="IFDVCND"/>
    <dbReference type="OrthoDB" id="382681at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="165" mass="19211" checksum="FC5ED7DBD2D6254A" modified="2017-02-15" version="1">MNENQNDDDNKGTRSNKILRGSLLDDQFNESNSNKLFLCNEKYDDETEEFYSRKKINAEKPNIDRSLINNFSTEKYREFLVKIEKSNQDLNNMDSESVRIDKDMLNPPDDNNEKTCVVMDVSMGIFDVCNENLCDSKLKDMNITVSEVIDKESVEKCEKDLIQEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWN1</accession>
    <name>A0A1J1GWN1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00430500</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529529.1">
        <property type="nucleotide sequence ID" value="XM_028673036.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWN1"/>
    <dbReference type="GeneID" id="39732837"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00430500"/>
    <dbReference type="OMA" id="FYTREPE"/>
    <dbReference type="OrthoDB" id="10253254at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000007">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001148">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15/PRP43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1080:FF:000003">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF109">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="205"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="393"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="66"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="75"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="86"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG96725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="846" mass="97116" checksum="AB95EB2DD1892341" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX26</accession>
    <name>A0A1J1GX26_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">COBW domain-containing protein 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">CBWD1</name>
        <name evidence="2" type="ORF">PGAL8A_00277300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528384.1">
        <property type="nucleotide sequence ID" value="XM_028671764.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX26"/>
    <dbReference type="GeneID" id="39731306"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00277300"/>
    <dbReference type="OMA" id="TELKCYE"/>
    <dbReference type="OrthoDB" id="258627at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03112">
        <property type="entry name" value="CobW-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051316">
        <property type="entry name" value="Zinc-reg_GTPase_activator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13748">
        <property type="entry name" value="COBW-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13748:SF31">
        <property type="entry name" value="ZINC-REGULATED GTPASE METALLOPROTEIN ACTIVATOR 1A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW/HypB/UreG nucleotide-binding" evidence="1">
        <location>
            <begin position="4"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="512" mass="60109" checksum="F1A7504C31A09F3B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX67</accession>
    <name>A0A1J1GX67_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein kish</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00448300</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Involved in the early part of the secretory pathway.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the KISH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529705.1">
        <property type="nucleotide sequence ID" value="XM_028673231.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX67"/>
    <dbReference type="GeneID" id="39733016"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00448300"/>
    <dbReference type="OMA" id="KVGFQGT"/>
    <dbReference type="OrthoDB" id="10034655at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051523">
        <property type="entry name" value="KISH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009653">
        <property type="entry name" value="Ksh1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13229">
        <property type="entry name" value="PROTEIN KISH-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06842">
        <property type="entry name" value="DUF1242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU910717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG96902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="72" mass="8025" checksum="BA1D0F2F192A72AD" modified="2017-02-15" version="1">MSALFNLESMITVIILCICTCTYLKPKFPNIFDNKKSGFLGTLGKFAIIGDRLSIYVSIACVILAFVNLFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX83</accession>
    <name>A0A1J1GX83_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Early transcribed membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ETRAMP</name>
        <name evidence="4" type="ORF">PGAL8A_00475800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529982.1">
        <property type="nucleotide sequence ID" value="XM_028673540.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX83"/>
    <dbReference type="GeneID" id="39733291"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00475800"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006389">
        <property type="entry name" value="Early_transc_mb_plasmodium"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01495">
        <property type="entry name" value="ETRAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09716">
        <property type="entry name" value="ETRAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012565845" evidence="3">
        <location>
            <begin position="25"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="243" mass="28111" checksum="94042E9AA150E776" modified="2017-02-15" version="1">MKLKKILIIFNFLLLINLISQCLCIHDLSKGDNTDSLKKIRKELEKKKKHKIILGSVLGGLALALSIGLGVAFSGKKKHRNKSYGDSPDNEFSKKGEFSKEDDFSKESESKERNDNSYFNLTPNKKPYDYYNFNYDVETGLNEFFDESLAGDIPNKTYEEMRSFTFNELQNHFNYYGPQYEHLIPYEYESIGVSIRDILLQNGIKASDEQVKQLEKEALSLYLNTGNFDPIGEFLYIDETRLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXB7</accession>
    <name>A0A1J1GXB7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00478000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530004.1">
        <property type="nucleotide sequence ID" value="XM_028673564.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXB7"/>
    <dbReference type="GeneID" id="39733313"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00478000"/>
    <dbReference type="OMA" id="IKLLCAY"/>
    <dbReference type="OrthoDB" id="361063at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="574"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="574"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="618" mass="73877" checksum="576D863EB9E62077" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXC3</accession>
    <name>A0A1J1GXC3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">WD-repeat protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00452200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529745.1">
        <property type="nucleotide sequence ID" value="XM_028673275.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXC3"/>
    <dbReference type="GeneID" id="39733055"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00452200"/>
    <dbReference type="OMA" id="ERCENKF"/>
    <dbReference type="OrthoDB" id="756370at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005656">
        <property type="term" value="C:nuclear pre-replicative complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120330">
        <property type="term" value="C:rixosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045227">
        <property type="entry name" value="WDR18/Ipi3/RID3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18763:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18763">
        <property type="entry name" value="WD-REPEAT PROTEIN 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="423" mass="49438" checksum="2DD52CB547624E8B" modified="2017-02-15" version="1">MEYNKIMLVYDNNEILLVNLDNERCENKYENSIKDKEKKICMLNNGNFIILNANRKVISQYLSTKNAAIYTKFVRVNLSVIKLTKNEKIIFGGDKIGNIYVWSSISGFLINYFQAHFGEVKDILIDQILNVVYTYSDDNIIHVYNLSDVLKKKKVKPMLLYQHNINASIRQIISVTPNIYDTYYTLISLTSNGNLHIFGLKSKKAVYILKTNTENCTYICSNEPFNTHLYLCKGNKIFRIPFTAFSKNNENNIKDLKCKKDIKLKEYGDYVQIVKKKSDDIFSNFKENEISKNENENESYLNLKDFTIFLGHKNDVIKCYVNDKKQIMISLAKDGIRIWDIFNCYTIKSLKYGENVIDFFVPNIKIHSYLIEFPNLTLEYEDDAKINFINEIKQNDCYINYKLFLGEENTLINMANMFATHGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXI8</accession>
    <name>A0A1J1GXI8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mitosis protein dim1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00453200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the DIM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529755.1">
        <property type="nucleotide sequence ID" value="XM_028673286.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXI8"/>
    <dbReference type="GeneID" id="39733065"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00453200"/>
    <dbReference type="OMA" id="GMYELYD"/>
    <dbReference type="OrthoDB" id="147752at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02954">
        <property type="entry name" value="DIM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000004">
        <property type="entry name" value="Spliceosomal protein DIB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004123">
        <property type="entry name" value="Dim1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12052:SF5">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12052">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEN 4A, 4B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02966">
        <property type="entry name" value="DIM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017199">
        <property type="entry name" value="mRNA_splic_U5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01410">
        <property type="entry name" value="DIM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4 6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR017199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="142" mass="16817" checksum="9B86B8454742564A" modified="2017-02-15" version="1">MSFMLQHLNSGWAVDQAILNEEERLVCIRFGHDYDPDCMKMDELLYKVAEDIKNFCVIYLVDITEVPDFNTMYELYDPVSVMFFYRNKHMMIDLGTGNNNKINWPMNNKQEFIDIVETIFRGARKGRGLVISPKDYSTKYKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXL0</accession>
    <name>A0A1J1GXL0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thioredoxin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00455600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529779.1">
        <property type="nucleotide sequence ID" value="XM_028673315.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXL0"/>
    <dbReference type="GeneID" id="39733089"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00455600"/>
    <dbReference type="OMA" id="KCIFEHE"/>
    <dbReference type="OrthoDB" id="443883at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="422" mass="50839" checksum="FA63324B2E76E9B1" modified="2017-02-15" version="1">MLIFNKSFHKIKDILKCSYKRKNIYISFQCICSNNIEKTPSKQVKSVQLKEYEDFVKVLQNNSIIINEIGKFVLIRKNSNLLYDRILFNPSSFDRLMEFVHFLEKNEVKSDYDIYFYEESLSNIKLNREQNKKEIFINIKEILKNKKMKNNEKKEYLEKKNINSLYYYNIQRYEDNLDPSSFLVDRRRLTKEEYTYQYISTILPYICFTFMIFFPHFLICLFIPHIKKKNERQKELCKILQIKKNIHSYKDINPEHIINIIDNNVKTIVFFYNNNIFLNMYLKSLLVNLSEIFKNNSISINIVGIDVSKYNIRYNIIKDFNENLFPLIYFILPYHYDNDSAVLKIEKPLSIENIVSQLRNFVHIPENAYKQIKALDDIGRKLKKCVFEYEIMNKNKEDILYDYGCEVAHLSCLLFNDKGLFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXL3</accession>
    <name>A0A1J1GXL3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00477500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529999.1">
        <property type="nucleotide sequence ID" value="XM_028673559.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXL3"/>
    <dbReference type="GeneID" id="39733308"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00477500"/>
    <dbReference type="OrthoDB" id="10464088at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="139" mass="16915" checksum="BFE2FBE97B9C500D" modified="2017-02-15" version="1">MLFMKNYYYFMHNKKINRKHYKKFGFYKNIKNRKPGDKKKKTRILSRSICHNIIEDLLNGLKLKNVNNVKETYDINIDEYLFDTFEKFCTSIFDDIPMWVLCSMFHVLYGCNSTRLNLSGFYYDLLLSNKKYAFDIFFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXN8</accession>
    <name>A0A1J1GXN8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00483500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530058.1">
        <property type="nucleotide sequence ID" value="XM_028673624.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXN8"/>
    <dbReference type="GeneID" id="39733368"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00483500"/>
    <dbReference type="OrthoDB" id="431068at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12254">
        <property type="entry name" value="RRM_hnRNPH_ESRPs_RBM12_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050666">
        <property type="entry name" value="ESRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13976">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="51"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="156" mass="18954" checksum="05E5815347559E22" modified="2017-02-15" version="1">MFFHMLKEKKVIIPKKYFKKNIHIPFINNGKFFKIVRSFTEYNIKEKINLPRLKLRGLPFDASEEEIRNFFKNFQLSKQGYPIHIIKGAKNKPTGHAYVYFDDEEEARNACKTLNRKFLRDRYVEIYIDYIFNHNLTPIKDHVTTLMRDRYKKDNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXY9</accession>
    <name>A0A1J1GXY9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ATP-dependent Clp protease proteolytic subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00308400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase S14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528680.1">
        <property type="nucleotide sequence ID" value="XM_028672093.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXY9"/>
    <dbReference type="GeneID" id="39731617"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00308400"/>
    <dbReference type="OMA" id="ERKVFLW"/>
    <dbReference type="OrthoDB" id="2017408at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009368">
        <property type="term" value="C:endopeptidase Clp complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051117">
        <property type="term" value="F:ATPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07017">
        <property type="entry name" value="S14_ClpP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000063">
        <property type="entry name" value="ATP-dependent Clp protease proteolytic subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381:SF11">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="232" mass="27065" checksum="B2B59997BED1A92E" modified="2017-02-15" version="1">MTCIYFCKCKKIVKRYNFMTYKINTNKFKKKKKIFFSDNEYHKHTINIPSLLLSKRIIFLSSPIYPHISEQIISQLLYLEYESKRKPIHLYINSTGDLENNKIINLNGITDVISIIDVINYISSDVYTYCLGKAYGISCILASSGKKGYRFSLKNSSFCLNQSYSIIPFNQATNIEIQNKEIMNTKKKVIEIIAKNTEKDKNLISDILERDRYFNADEAINFNLVDNILEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXZ6</accession>
    <name>A0A1J1GXZ6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ring-exported protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00475300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529977.1">
        <property type="nucleotide sequence ID" value="XM_028673535.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXZ6"/>
    <dbReference type="GeneID" id="39733286"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00475300"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012520583" description="Ring-exported protein 3" evidence="1">
        <location>
            <begin position="28"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="208" mass="25457" checksum="6B1270858617A6F8" modified="2017-02-15" version="1">MMFSKNFIIYFFSLLFLLLHCMHDMLHKENLRLVLERRYVRILAENNREDDICIKTQNKEEDSPDEVLDMLNEFIQKVEKEWEELNKMQKFKDSELKLMLTYEMYLSASTEEYRENLSEYNDLLDIVQAQNEAPLNEVNQMFCKWKSDLKDRIVEGKIINWQNVVEDEWNQIKEKKMQNTNDRSDKIKQAYKDWLTIKFPSFNHNFEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY09</accession>
    <name>A0A1J1GY09_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alpha/beta hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00502300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530251.1">
        <property type="nucleotide sequence ID" value="XM_028673838.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY09"/>
    <dbReference type="GeneID" id="39733556"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00502300"/>
    <dbReference type="OrthoDB" id="364221at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012678574" description="Alpha/beta hydrolase" evidence="1">
        <location>
            <begin position="20"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="473" mass="56433" checksum="48955A90A690A94F" modified="2017-02-15" version="1">MKISLLIYIVIFFFKENLGIKIYTNDSAIFDINKVFKNKFSLLYRKGNKLNNYFFSYVTKNGKNNKCYQYIQDALYDSNTQIMKEEVFKCLKTSKDILHKTFFDIINKLFLYIKNVFLKKYFIFFLLYLINFNCDSLVSQLNDPYVLNNYNLSENATPGMYNMKYEEIEIPSFNNIKGWLIKSNKKSNKLFLLLHGYNSNRQACLFFLNILKKLNINHDTNIFIPDVRNFNDKGVEDIYNILNYFKENMGLNDVNIYTQSSTNLLVLLLSKHYKNKIINKSKQKFINNIISYNNEKKDENNVIYIDKYIFDSPILNLHKTIDIHFNLNDINKKINQDKNNNNYNVNIYDKKAMFKYFISFFMWLLNNQLKGQLYDFDFNKLINENNINPSNIYILHSLNDNISLLNTLTQEIKENRLLPLKNIYIFKNGKHANIYESSKNEYDLVIKRILKGFNLLDLIYYIPMKSKMSTLNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY34</accession>
    <name>A0A1J1GY34_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Dynein light chain roadblock</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00479300</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Cytoplasm</location>
            <location evidence="1 10">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the GAMAD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530017.1">
        <property type="nucleotide sequence ID" value="XM_028673579.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY34"/>
    <dbReference type="GeneID" id="39733326"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00479300"/>
    <dbReference type="OMA" id="NNSTIEY"/>
    <dbReference type="OrthoDB" id="9985637at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.30:FF:000009">
        <property type="entry name" value="Dynein light chain roadblock"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.30">
        <property type="entry name" value="Dynein light chain 2a, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016561">
        <property type="entry name" value="DYNLRB1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004942">
        <property type="entry name" value="Roadblock/LAMTOR2_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10779">
        <property type="entry name" value="DYNEIN LIGHT CHAIN ROADBLOCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03259">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009998">
        <property type="entry name" value="DLC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00960">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103196">
        <property type="entry name" value="Roadblock/LC7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0966">Cell projection</keyword>
    <keyword evidence="12" id="KW-0969">Cilium</keyword>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6 10" id="KW-0243">Dynein</keyword>
    <keyword evidence="12" id="KW-0282">Flagellum</keyword>
    <keyword evidence="5 10" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7 10" id="KW-0505">Motor protein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Roadblock/LAMTOR2" evidence="11">
        <location>
            <begin position="4"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR009998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG97214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="101" mass="11729" checksum="B931738A2E064205" modified="2017-02-15" version="1">MNEAEEILNRIKNHKGVIGILVINNEGLIIKSTFDQQQSDLHASLLTQLSNKARDVIRELDPQNDINFLRLRSKKHEIMIAPDKDYTLIVVQDPYYDKEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYW5</accession>
    <name>A0A1J1GYW5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription initiation factor IIF subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00372100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529301.1">
        <property type="nucleotide sequence ID" value="XM_028672783.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYW5"/>
    <dbReference type="GeneID" id="39732251"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00372100"/>
    <dbReference type="OMA" id="NCEHTYS"/>
    <dbReference type="OrthoDB" id="26094at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="310" mass="36448" checksum="DD2DFDF17344358A" modified="2017-02-15" version="1">MINSKENDTLPKISFKNKNIKLIKVPKFVSNKWLKRKHRDVVGLFEHKNNEISNLYIQKDDSDEVKKLTCNKNYTINTYILKQNKISLKPNKGTNPSNNNLNNKTIENSNQNKLKININNPINENSERNKELDYVICADVIKNCEHTYSFLPLLDEDYSLILKERHYNTNIKKNRYTIIETRNEENLDSSQTLFKYYTSDDNNNLNKDKNNKNNKRVLLENENNFNSSSAASKQKTKQAKKFHIFDLDKTKISMFKIFEREGKKGVPFSFFAKSFNIPSNHIKNILDEIAVKRKRASDKKSVYFLKDYIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYZ3</accession>
    <name>A0A1J1GYZ3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00023800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530603.1">
        <property type="nucleotide sequence ID" value="XM_028674229.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYZ3"/>
    <dbReference type="GeneID" id="39728761"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00023800"/>
    <dbReference type="OMA" id="NNANEQM"/>
    <dbReference type="OrthoDB" id="372053at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="557"/>
            <end position="669"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="807" mass="97916" checksum="EF7E562F4727A073" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ02</accession>
    <name>A0A1J1GZ02_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00526900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530494.1">
        <property type="nucleotide sequence ID" value="XM_028674108.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ02"/>
    <dbReference type="GeneID" id="39733802"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00526900"/>
    <dbReference type="OrthoDB" id="361667at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="717" mass="86412" checksum="990920D32022C611" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ57</accession>
    <name>A0A1J1GZ57_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00031100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530675.1">
        <property type="nucleotide sequence ID" value="XM_028674308.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ57"/>
    <dbReference type="GeneID" id="39728834"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00031100"/>
    <dbReference type="OMA" id="EMCLCLD"/>
    <dbReference type="OrthoDB" id="377579at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="521"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="363"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="852" mass="102353" checksum="3B61719C110E9ED1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ68</accession>
    <name>A0A1J1GZ68_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00029700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530661.1">
        <property type="nucleotide sequence ID" value="XM_028674293.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ68"/>
    <dbReference type="GeneID" id="39728820"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00029700"/>
    <dbReference type="OMA" id="CRNMITI"/>
    <dbReference type="OrthoDB" id="31154at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31437:SF1">
        <property type="entry name" value="PROTEIN SREK1IP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31437">
        <property type="entry name" value="SREK1IP1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="107"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="107"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="128"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="163"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="222"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="240"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="273" mass="31702" checksum="2453018BBB55C820" modified="2017-02-15" version="1">MPSKTGRVRMPADNRLPVSASLKTSEIWKNSVGYDPYASIEEINNKKNAKTEEINEKAQSLFNLARLTGNVSSTIPGACSLCNHVGHLPYQCRNFINLEKQNFKKDMKENSEDELKERKNLGLISSESENESESESESESESESKSESESDSESNFSDDSSYKKKKIKKIKKKNHRHEKLKHSKNKHKKHKKSENEHERYKCKKNIHKKSKDRKALKKNKNGYKDIDKKYEHDNHDSSKNYKKLKVKDKKIKKKKKYKSKNKNKKYKGSSSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZJ1</accession>
    <name>A0A1J1GZJ1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Histone-lysine N-methyltransferase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00528800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530512.1">
        <property type="nucleotide sequence ID" value="XM_028674128.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZJ1"/>
    <dbReference type="GeneID" id="39733821"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00528800"/>
    <dbReference type="OrthoDB" id="3180714at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009207">
        <property type="entry name" value="SET7_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF022536">
        <property type="entry name" value="A612L_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="33"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="173" mass="20345" checksum="8CB0A435B1F88746" modified="2017-02-15" version="1">MIIVKRNFHNYFAKNALKEILKKENINFNDIHKKVYIGNSIYSGLGVFSFDILKKNEIIEVCPTIEIENEEMPKILVDYLFESEKGNINKKIVDILTKKKETKRNKLLPLGYGMLYNHSNTPNAFVHIFPINQNKETVTSNKIMIFYAEQDIQKNEEIFISYGESWWNVSLYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZN2</accession>
    <name>A0A1J1GZN2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fe-S-cluster redox enzyme, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00434300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NifU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529565.1">
        <property type="nucleotide sequence ID" value="XM_028673075.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZN2"/>
    <dbReference type="GeneID" id="39732875"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00434300"/>
    <dbReference type="OMA" id="YYELNHE"/>
    <dbReference type="OrthoDB" id="565552at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="entry name" value="Fe-S cluster assembly (FSCA)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001075">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11178">
        <property type="entry name" value="IRON-SULFUR CLUSTER SCAFFOLD PROTEIN NFU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11178:SF25">
        <property type="entry name" value="NIFU-LIKE PROTEIN 3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01106">
        <property type="entry name" value="NifU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="Fe-S cluster assembly (FSCA) domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NIF system FeS cluster assembly NifU C-terminal" evidence="2">
        <location>
            <begin position="81"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="236" mass="27958" checksum="B05DFC5F883DF515" modified="2017-02-15" version="1">MKHFFFFFLTVIYLFLLNEITSLKFTKKNLLFIYSNFDLFNNKILNSSLNTLKNKRKTKLKILSSPEKDEEIYYELNHENVEKVLNLIRPKLQIDNGDVELVKIKNNDLYIRLLGNCVTCSSNSVTVSQVIKKTLKKYIRNEKKEEPNVIITNFDEINKENIQNCLNQLKPYFDFLKVEIIIKDIVINKENINNSVSLKFQNFDDSEEIKIPFNIKNEVTERLKQKFPTLTVNFEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZQ9</accession>
    <name>A0A1J1GZQ9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nitric oxide synthase-interacting protein zinc-finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00039600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the NOSIP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530758.1">
        <property type="nucleotide sequence ID" value="XM_028674401.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZQ9"/>
    <dbReference type="GeneID" id="39728920"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00039600"/>
    <dbReference type="OMA" id="LENVHEH"/>
    <dbReference type="OrthoDB" id="116827at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016818">
        <property type="entry name" value="NOSIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031790">
        <property type="entry name" value="Znf-NOSIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13063">
        <property type="entry name" value="ENOS INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13063:SF10">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15906">
        <property type="entry name" value="zf-NOSIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF023577">
        <property type="entry name" value="ENOS_interacting"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitric oxide synthase-interacting protein zinc-finger" evidence="6">
        <location>
            <begin position="4"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="68"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR023577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF15906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="270" mass="31901" checksum="106FDA260D4BE04E" modified="2017-02-15" version="1">MPRHSKNNTANPIFTYHERKKVKDVGTLKERLGKDSMRKFEQCWICLRNAEYPVSTPYGHIFCKMCIINNLLKQKKEYSRKKKEYNDYIKELKKKKKDEANYEKEKEKKKFIEDLESINNNEKDKNEEKKNLLDISNNFWLSNNSKVKKDIIQKKLKPPLKNLICPISRKPLKMNDLITINPEVPNKNESTKENWICSFSKKSIDHHKAVLIKKTGQIILKSFFESYIYNKKNSWEFSVGEGDFIDLQPGGTAFCSHSNVEKTLYREPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0H4</accession>
    <name>A0A1J1H0H4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">60S ribosomal protein L2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RPL2</name>
        <name evidence="7" type="ORF">PGAL8A_00038400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530746.1">
        <property type="nucleotide sequence ID" value="XM_028674388.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0H4"/>
    <dbReference type="GeneID" id="39728908"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00038400"/>
    <dbReference type="OMA" id="GGRHPCT"/>
    <dbReference type="OrthoDB" id="10267824at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000020">
        <property type="entry name" value="60S ribosomal protein L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.950.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000006">
        <property type="entry name" value="60S ribosomal protein L8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.950.10">
        <property type="entry name" value="Ribosomal protein L2, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002171">
        <property type="entry name" value="Ribosomal_uL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023672">
        <property type="entry name" value="Ribosomal_uL2_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022669">
        <property type="entry name" value="Ribosomal_uL2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022671">
        <property type="entry name" value="Ribosomal_uL2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014726">
        <property type="entry name" value="Ribosomal_uL2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022666">
        <property type="entry name" value="Ribosomal_uL2_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007180">
        <property type="entry name" value="PRK09612.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691:SF16">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691">
        <property type="entry name" value="RIBOSOMAL PROTEIN L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03947">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00181">
        <property type="entry name" value="Ribosomal_L2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002158">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01383">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01382">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00467">
        <property type="entry name" value="RIBOSOMAL_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL2 RNA-binding" evidence="6">
        <location>
            <begin position="11"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL2 C-terminal" evidence="5">
        <location>
            <begin position="96"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="260" mass="27976" checksum="00034EA721714A55" modified="2017-02-15" version="1">MGRVIRGQRKGRGSIFKSHNHHRKGAAKLRHLDYCEKKGYIKGLVKDIIHDPGRGAPLAKVIFKRTDKYGKKEELMVATEGMFTGQYISCGTKAPLSVGNILPVGKMPEGTLICNLEHRTGNRGTLVKASGCYATVVGQSEDGKKTKVRLPSGAKKTIDSKARAMVGVVGAGGRIDKPILKAGVAYHKYKVKRNCWPKVRGVAMNPVEHPHGGGNHQHIGHPSTVSRSAPAGQKVGLIAARRTGLLRGAKKSKLVGKSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H167</accession>
    <name>A0A1J1H167_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transcription factor with AP2 domain(S), putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ApiAP2</name>
        <name evidence="9" type="ORF">PGAL8A_00460900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529832.1">
        <property type="nucleotide sequence ID" value="XM_028673373.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733142"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00460900"/>
    <dbReference type="OrthoDB" id="371759at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2050">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028078">
        <property type="entry name" value="ACDC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14733">
        <property type="entry name" value="ACDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00847">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="7">
        <location>
            <begin position="1879"/>
            <end position="1927"/>
        </location>
    </feature>
    <feature type="domain" description="AP2/ERF" evidence="7">
        <location>
            <begin position="1975"/>
            <end position="2026"/>
        </location>
    </feature>
    <feature type="domain" description="AP2-coincident C-terminal" evidence="8">
        <location>
            <begin position="2078"/>
            <end position="2167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="257"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="901"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="955"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1190"/>
            <end position="1306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1367"/>
            <end position="1387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1520"/>
            <end position="1539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="24"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="271"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="957"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1204"/>
            <end position="1216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1219"/>
            <end position="1228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1236"/>
            <end position="1259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1283"/>
            <end position="1301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1526"/>
            <end position="1539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF14733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG97029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2200" mass="258737" checksum="CEDAA39E72B85305" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1P5</accession>
    <name>A0A1J1H1P5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">U3 small nucleolar RNA-associated protein 6, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00503200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530260.1">
        <property type="nucleotide sequence ID" value="XM_028673848.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1P5"/>
    <dbReference type="GeneID" id="39733565"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00503200"/>
    <dbReference type="OMA" id="CLFENRH"/>
    <dbReference type="OrthoDB" id="28112at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034388">
        <property type="term" value="C:Pwp2p-containing subcomplex of 90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013949">
        <property type="entry name" value="Utp6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055347">
        <property type="entry name" value="UTP6_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23271">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN 66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23271:SF1">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 6 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08640">
        <property type="entry name" value="U3_assoc_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="U3 small nucleolar RNA-associated protein 6 N-terminal" evidence="7">
        <location>
            <begin position="9"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="296"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="718"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="113"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="298"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="718"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="756"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="819"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="856"/>
            <end position="878"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="996" mass="120412" checksum="A9E5C583EE9DE8DB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2X9</accession>
    <name>A0A1J1H2X9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00527000</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynein intermediate chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530495.1">
        <property type="nucleotide sequence ID" value="XM_028674109.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2X9"/>
    <dbReference type="GeneID" id="39733803"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00527000"/>
    <dbReference type="OMA" id="NCFEPIY"/>
    <dbReference type="OrthoDB" id="366230at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036157">
        <property type="term" value="C:outer dynein arm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045504">
        <property type="term" value="F:dynein heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045503">
        <property type="term" value="F:dynein light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003341">
        <property type="term" value="P:cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036158">
        <property type="term" value="P:outer dynein arm assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050687">
        <property type="entry name" value="Dynein_IC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442:SF11">
        <property type="entry name" value="DYNEIN AXONEMAL INTERMEDIATE CHAIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442">
        <property type="entry name" value="DYNEIN INTERMEDIATE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0966">Cell projection</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0243">Dynein</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8" id="KW-0505">Motor protein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="1020"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="154"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG97694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1176" mass="139796" checksum="9F1E056739CB4871" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL87</accession>
    <name>A0A1J1GL87_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Actin-related protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ARP6</name>
        <name evidence="4" type="ORF">PGAL8A_00082500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525943.1">
        <property type="nucleotide sequence ID" value="XM_028670721.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL87"/>
    <dbReference type="GeneID" id="39729349"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00082500"/>
    <dbReference type="OrthoDB" id="6220758at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="476"/>
            <end position="519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="873" mass="103476" checksum="1850921594FFE351" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLC1</accession>
    <name>A0A1J1GLC1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">LEM3/CDC50 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00082700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CDC50/LEM3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525945.1">
        <property type="nucleotide sequence ID" value="XM_028670743.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLC1"/>
    <dbReference type="GeneID" id="39729351"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00082700"/>
    <dbReference type="OrthoDB" id="340608at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005045">
        <property type="entry name" value="CDC50/LEM3_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10926:SF0">
        <property type="entry name" value="CDC50, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10926">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03381">
        <property type="entry name" value="CDC50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="252"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="520"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="182"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="22"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="551" mass="65640" checksum="84EE09BD8D5E5761" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLN1</accession>
    <name>A0A1J1GLN1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">40S ribosomal protein S10, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00082900</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic ribosomal protein eS10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525947.1">
        <property type="nucleotide sequence ID" value="XM_028670766.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLN1"/>
    <dbReference type="GeneID" id="39729353"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00082900"/>
    <dbReference type="OMA" id="AYFFITD"/>
    <dbReference type="OrthoDB" id="5211809at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000388">
        <property type="entry name" value="plectin isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005326">
        <property type="entry name" value="Plectin_eS10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037447">
        <property type="entry name" value="Ribosomal_eS10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12146">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12146:SF0">
        <property type="entry name" value="RIBOSOMAL PROTEIN S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03501">
        <property type="entry name" value="S10_plectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Plectin/eS10 N-terminal" evidence="6">
        <location>
            <begin position="14"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="137" mass="16581" checksum="2080402E0D4AEF77" modified="2017-02-15" version="1">MEKKLLPHHKYSYIPKQNKKLIYEYLFKEGVIVVEKDAKIPRHPHLNIPNLHIMMTLKSLKSRNYVEEKYNWKHQYFILNNEGIEYLREFLHLPPSIFPATLSKKTVNRAPKIDEEITREIRQPMGRGRPYDRRNLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM37</accession>
    <name>A0A1J1GM37_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00112600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526242.1">
        <property type="nucleotide sequence ID" value="XM_028674043.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM37"/>
    <dbReference type="GeneID" id="39729651"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00112600"/>
    <dbReference type="OMA" id="LVDCCYW"/>
    <dbReference type="OrthoDB" id="329227at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17039">
        <property type="entry name" value="Ubl_ubiquitin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="92"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="232" mass="26858" checksum="D200F7E92E22EAF2" modified="2017-02-15" version="1">MYVTVGNNDILVSINDFVNKNSTTYQLTDINNEMRISEIINKIKAKKNYTHDASSLVLYFARVECKMNEKLSTYNKSNRKSIKLELYLSSLITINVRTLQSCGSGTSRCIPLWSLCCRQTIKVKILDTCEVRALKQKIYNMTDESSSISVDNIVLLYKGAPLNNFLTLKESELVNNCRVDYFVPLCYIYKENKENKENEENEKKEEKEENKEKEEIEDKGENNDEVANKNEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM50</accession>
    <name>A0A1J1GM50_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00110900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526225.1">
        <property type="nucleotide sequence ID" value="XM_028673854.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM50"/>
    <dbReference type="GeneID" id="39729634"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00110900"/>
    <dbReference type="OMA" id="IRLMSCC"/>
    <dbReference type="OrthoDB" id="1919336at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.30.10:FF:000037">
        <property type="entry name" value="High mobility group protein B2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050342">
        <property type="entry name" value="HMGB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN DSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112:SF22">
        <property type="entry name" value="MITOCHONDRIAL TRANSCRIPTION FACTOR A, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00886">
        <property type="entry name" value="HIGHMOBLTY12"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="5">
        <location>
            <begin position="24"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="24"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="99" mass="11525" checksum="6306ED24913AD307" modified="2017-02-15" version="1">MATKTQKKVLKKQNKKKKKDPLAPKRALSAYMFYVKDKRLEIIKEKPELAKDVAQVGKLIGEAWGKLSAAQKSPYEKKAQLDKARYSKEIEEYRKKNKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMH1</accession>
    <name>A0A1J1GMH1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">SANT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00126300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526378.1">
        <property type="nucleotide sequence ID" value="XM_028674782.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMH1"/>
    <dbReference type="GeneID" id="39729788"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00126300"/>
    <dbReference type="OMA" id="MQEIHNT"/>
    <dbReference type="OrthoDB" id="118550at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032451">
        <property type="entry name" value="SMARCC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007526">
        <property type="entry name" value="SWIRM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16495">
        <property type="entry name" value="SWIRM-assoc_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50934">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="SWIRM" evidence="6">
        <location>
            <begin position="402"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="5">
        <location>
            <begin position="832"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="7">
        <location>
            <begin position="835"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1035"/>
            <end position="1110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1220" mass="143638" checksum="EA8F0BD8D7CEF4D1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMJ7</accession>
    <name>A0A1J1GMJ7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00136700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526484.1">
        <property type="nucleotide sequence ID" value="XM_028674899.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMJ7"/>
    <dbReference type="GeneID" id="39729892"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00136700"/>
    <dbReference type="OMA" id="REWKQFM"/>
    <dbReference type="OrthoDB" id="368993at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="151" mass="18734" checksum="EDF93CF5E657F0D8" modified="2017-02-15" version="1">MTKKNIFMFFRLIHFKSAREWKQFMNPKIDRTRIKKIRNVSENDMIHKHRILKYPYFKMKRIGSYSKIIKNNDFLFNRDIEILYDYRYCSIFEKLKDIISFYLKGIVIKEKCTNDLCFEIYDCLQNKVLIKRKNEELEAEELFKEMLEKMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GML0</accession>
    <name>A0A1J1GML0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00134600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526463.1">
        <property type="nucleotide sequence ID" value="XM_028674875.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GML0"/>
    <dbReference type="GeneID" id="39729871"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00134600"/>
    <dbReference type="OMA" id="KFESCDE"/>
    <dbReference type="OrthoDB" id="4726at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32343">
        <property type="entry name" value="SERINE/ARGININE-RICH SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="9"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="159"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="347"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="482"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="361"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="389"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="418"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="438"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="449"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="504" mass="59110" checksum="DFFB911AEDAAC479" modified="2017-02-15" version="1">MSLNFSIANVVYVKNLSTDVSEKDIKEKFESCDEIINITFKNFPGKNQKYCQIEFKSSEGITKASRLNGELLLNVPMVVTVIEPVSHNFNEISNNENEKNLNSDLRNIHINNNIQNNITNQNVQNILLQKQLISEQKKGLVDFQNSLNAKNNKFDVFSKIVYMENIPENFDEEDIKKFFKNVGKTTNYKIQYNEHKKLYTAFVEFKNEEHAKAALNLNGNKVGKNEICIRDAYSLINEKDILKNNFSLCSNSKDDINVSNKQTVNEKVEKVLALKEKLTLKLCAMYKPNLLLVNNLVKANPFLLNTNIENEENKNIEKCVDETKKEIINNSNDIKLVKSDIPTDKSCEEEKKMKKRKNSKSKYSNSILSGKSYSDNSSRSSSYDDSYRRSSKTSSKKKKILKKHKSSKRRKKYKSRSKSSYYYSRSNSRSSYESEKLRYKKKKKKKYRNSSSSYSDSSYSSRRKYRESSNYKPWWVKESEKMQMRQRMKEKQMREIAMREKYRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMS5</accession>
    <name>A0A1J1GMS5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Haloacid dehalogenase-like hydrolase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">HAD3</name>
        <name evidence="1" type="ORF">PGAL8A_00127200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526387.1">
        <property type="nucleotide sequence ID" value="XM_028674792.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMS5"/>
    <dbReference type="GeneID" id="39729797"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00127200"/>
    <dbReference type="OMA" id="MDGVYSH"/>
    <dbReference type="OrthoDB" id="27226at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10000:SF8">
        <property type="entry name" value="HAD SUPERFAMILY HYDROLASE-LIKE, TYPE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10000">
        <property type="entry name" value="PHOSPHOSERINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08282">
        <property type="entry name" value="Hydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="299" mass="33923" checksum="91DF4F3449B0E2A0" modified="2017-02-15" version="1">MHKNNIKLIAIDIDGTLANYENRVSNENLRAMHIAKKLGINVILATGRSHGYALQIFDQDQIDQYKMDKYDGVFSDGASVYIKGNNFVYRKFSNRDFDTLMFALAHYNLFNYAVFITKDSAYVVVEDPNLPNILVKEHEGIKSSVKYIVTLDRGLEAIVLNNIKDISSIGDILIVHIYREVYEGQEPFNDFFRTLHDELKQNFKVYITEHNDKIVISPLNTSKLVGVELYARLYNININNILSIGNDLNDVQLLSSTGYSVAVKNAIKEVSDIAKCVSTKTNDEHSIADIIYKVISGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMV1</accession>
    <name>A0A1J1GMV1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00136400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526481.1">
        <property type="nucleotide sequence ID" value="XM_028674896.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMV1"/>
    <dbReference type="GeneID" id="39729889"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00136400"/>
    <dbReference type="OrthoDB" id="372586at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="532"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="71"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="707"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="305"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="71"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="707"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="723"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="744"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="755"/>
            <end position="773"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="773" mass="92694" checksum="B04EA124BB4B25A1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMX1</accession>
    <name>A0A1J1GMX1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00150900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526622.1">
        <property type="nucleotide sequence ID" value="XM_028675052.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMX1"/>
    <dbReference type="GeneID" id="39730033"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00150900"/>
    <dbReference type="OMA" id="VHRMTVY"/>
    <dbReference type="OrthoDB" id="333425at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="124" mass="15506" checksum="1A4A6AACABBE48B9" modified="2017-02-15" version="1">MRKLFHNRCNRKSKEFFKVLNFSTFEKNENLDLENFINDLKTDESKSWEYYIKGINPDYEPRREMYNFLKSKNINVHRMTVYEIECFTKWLLMRKIYGNKFPRFPYEITFEDKIEELKEKYPLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN51</accession>
    <name>A0A1J1GN51_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SWI/SNF-related matrix-associated actin-dependent, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00139900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526515.1">
        <property type="nucleotide sequence ID" value="XM_028674933.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN51"/>
    <dbReference type="GeneID" id="39729923"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00139900"/>
    <dbReference type="OMA" id="RCIDMSN"/>
    <dbReference type="OrthoDB" id="10263741at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00855">
        <property type="entry name" value="SWIB-MDM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.245.10">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019835">
        <property type="entry name" value="SWIB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036885">
        <property type="entry name" value="SWIB_MDM2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003121">
        <property type="entry name" value="SWIB_MDM2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13844">
        <property type="entry name" value="SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02201">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00151">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47592">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SWIB" evidence="1">
        <location>
            <begin position="253"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="832" mass="99020" checksum="5C1A31E65944246C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNA2</accession>
    <name>A0A1J1GNA2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00152900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526641.1">
        <property type="nucleotide sequence ID" value="XM_028675073.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNA2"/>
    <dbReference type="GeneID" id="39730053"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00152900"/>
    <dbReference type="OMA" id="CVYNIYV"/>
    <dbReference type="OrthoDB" id="364384at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012430209" evidence="1">
        <location>
            <begin position="21"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="556" mass="66586" checksum="6F7DB18E2AE2EF9D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNS8</accession>
    <name>A0A1J1GNS8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Zinc finger protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00165100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526763.1">
        <property type="nucleotide sequence ID" value="XM_028675208.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNS8"/>
    <dbReference type="GeneID" id="39730176"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00165100"/>
    <dbReference type="OMA" id="ENRCKEG"/>
    <dbReference type="OrthoDB" id="410307at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045877">
        <property type="entry name" value="ZFP36-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12547">
        <property type="entry name" value="CCCH ZINC FINGER/TIS11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12547:SF18">
        <property type="entry name" value="PROTEIN TIS11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="9"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="44"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="81"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="9"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="44"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="81"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="315"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="559"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="316"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="326"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="338"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="563"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="580"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="595"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="874" mass="103385" checksum="D9D060FDFAAB00BE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNU6</accession>
    <name>A0A1J1GNU6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nuclear fusion protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00170300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG93996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526817.1">
        <property type="nucleotide sequence ID" value="XM_028670024.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNU6"/>
    <dbReference type="GeneID" id="39730230"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00170300"/>
    <dbReference type="OMA" id="FHYFPSP"/>
    <dbReference type="OrthoDB" id="377549at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040346">
        <property type="entry name" value="GEX1/Brambleberry"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33538">
        <property type="entry name" value="PROTEIN GAMETE EXPRESSED 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33538:SF2">
        <property type="entry name" value="PROTEIN GAMETE EXPRESSED 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="345"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="35"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="642" mass="76727" checksum="35F12158B084827A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNV3</accession>
    <name>A0A1J1GNV3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glideosome-associated connector</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00168200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526795.1">
        <property type="nucleotide sequence ID" value="XM_028669999.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730208"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00168200"/>
    <dbReference type="OMA" id="YVNGVHD"/>
    <dbReference type="OrthoDB" id="7537227at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22895">
        <property type="entry name" value="ARMADILLO REPEAT-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22895:SF0">
        <property type="entry name" value="ARMADILLO REPEAT-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2605" mass="290586" checksum="5B7B7DC85C9412E7" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNX4</accession>
    <name>A0A1J1GNX4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Swt1-like HEPN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00170500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG93998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526819.1">
        <property type="nucleotide sequence ID" value="XM_028670026.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNX4"/>
    <dbReference type="GeneID" id="39730232"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00170500"/>
    <dbReference type="OMA" id="FWANQEI"/>
    <dbReference type="OrthoDB" id="365277at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.270.50">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041650">
        <property type="entry name" value="HEPN_Swt1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18731">
        <property type="entry name" value="HEPN_Swt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Swt1-like HEPN" evidence="1">
        <location>
            <begin position="627"/>
            <end position="734"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="762" mass="89323" checksum="09423560AC4AE722" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP35</accession>
    <name>A0A1J1GP35_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00387700</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleavage of peptide bonds with very broad specificity.</text>
            <dbReference type="EC" id="3.4.25.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the proteasome complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the peptidase T1B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526994.1">
        <property type="nucleotide sequence ID" value="XM_028670220.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP35"/>
    <dbReference type="GeneID" id="39732407"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00387700"/>
    <dbReference type="OMA" id="IQIEMAH"/>
    <dbReference type="OrthoDB" id="37597at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005839">
        <property type="term" value="C:proteasome core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03761">
        <property type="entry name" value="proteasome_beta_type_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000051">
        <property type="entry name" value="Proteasome subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000243">
        <property type="entry name" value="Pept_T1A_subB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF3">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00141">
        <property type="entry name" value="PROTEASOME"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="6 10 11" id="KW-0647">Proteasome</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0888">Threonine protease</keyword>
    <keyword evidence="7" id="KW-0865">Zymogen</keyword>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR600243-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG94173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="269" mass="30347" checksum="54541110B8248E9B" modified="2017-02-15" version="1">MIESENFMNEIDNLINDSEEDKINNDELQFSIAPVDIPRNFIKDAKTKNSKLFDFHKGTTTLAFKFKEGIIVAVDSRASMGSFISSPNVEKIIEINKNILGTMAGGAADCLYWEKYLGKIIKIYELRNNDKISVRAASTILSNILYQYKGYGLCCGIILSGYDHTGFNMFYVDDSGKKVEGNLFSCGSGSTYAYSILDSSYDYNLNLEQAVELARNAIYHATFRDGGSGGKVRVYYIHKSGYDKIIEGEDVFDLHYHYTNPLQKDQYVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP49</accession>
    <name>A0A1J1GP49_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Microtubule and actin binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00394600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527063.1">
        <property type="nucleotide sequence ID" value="XM_028670296.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732476"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00394600"/>
    <dbReference type="OMA" id="MIDENEY"/>
    <dbReference type="OrthoDB" id="378346at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="350"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="410"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="822"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="980"/>
            <end position="1412"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1445"/>
            <end position="1692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="350"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="376"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1698" mass="203141" checksum="3505A95E6B7DB080" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPR5</accession>
    <name>A0A1J1GPR5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">HVA22/TB2/DP1 family protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00399600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the DP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527113.1">
        <property type="nucleotide sequence ID" value="XM_028670352.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPR5"/>
    <dbReference type="GeneID" id="39732526"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00399600"/>
    <dbReference type="OMA" id="DTQYWVV"/>
    <dbReference type="OrthoDB" id="10009287at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004345">
        <property type="entry name" value="TB2_DP1_HVA22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300">
        <property type="entry name" value="HVA22-LIKE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300:SF161">
        <property type="entry name" value="RECEPTOR EXPRESSION-ENHANCING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03134">
        <property type="entry name" value="TB2_DP1_HVA22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="157"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="236" mass="27742" checksum="F2AF8294393D48EC" modified="2017-02-15" version="1">MDKIKEYDKEKEQEKCNVVQGVQGIKKLSSKVLSDKLNNLDVSKVFDNIDDHIKKHPFINDLAKKFGVKPSYIIVPFFFFLFISLIFGWGAALICNVLGFAYPGIIKKINRLKRETYQSFKAVESQSTDETKLWLTYWVVFSLFFFLEYLIDIILFWIPFYYLIKLLFLLYLYMPQVRGAEMVYNFIIRPILLKHEKTIDDTVQKISQTATSHLTQITGNLTEKLVQEGIRRRNVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPT2</accession>
    <name>A0A1J1GPT2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00400600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527123.1">
        <property type="nucleotide sequence ID" value="XM_028670363.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPT2"/>
    <dbReference type="GeneID" id="39732536"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00400600"/>
    <dbReference type="OMA" id="KNEAHEY"/>
    <dbReference type="OrthoDB" id="371323at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="242"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="267"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="319"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="347"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="419"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="718"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="748"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="783"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="810"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="894"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="933"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="526"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="984" mass="116608" checksum="E9EAAB0D699040CF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ09</accession>
    <name>A0A1J1GQ09_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">60S ribosomal protein L1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00200400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527422.1">
        <property type="nucleotide sequence ID" value="XM_028670695.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ09"/>
    <dbReference type="GeneID" id="39730530"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00200400"/>
    <dbReference type="OMA" id="GPRNKMP"/>
    <dbReference type="OrthoDB" id="2449818at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00403">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.190.20:FF:000006">
        <property type="entry name" value="Ribosomal protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.790:FF:000002">
        <property type="entry name" value="Ribosomal protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.190.20:FF:000009">
        <property type="entry name" value="Ribosomal protein L10a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050257">
        <property type="entry name" value="eL8/uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002143">
        <property type="entry name" value="Ribosomal_uL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_uL1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_uL1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23105">
        <property type="entry name" value="RIBOSOMAL PROTEIN L7AE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002155">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="Ribosomal protein L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="217" mass="24747" checksum="F9F0905649440FBC" modified="2017-02-15" version="1">MSKLNQDLLKKAIADVFEGTRQKKRKFVETIELQIGLKDYDTQRDKRFSGTVKLSNEVRKKLKVCILGDAVHVEEAQKLQLDYMDIEAMKKLNKDKTLVKKLAKKYDAFLASQVILPQIPKLLGPGLNKAGKFPSLITHNDKINDKINELKSSIKFQLKKVLCMGVPVGHANLKEDELRSNIVHAINFLVSLLKKNWQNIKTLHIKSTMGKPQRIYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ18</accession>
    <name>A0A1J1GQ18_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cytoplasmic tRNA 2-thiolation protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00200200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527420.1">
        <property type="nucleotide sequence ID" value="XM_028670693.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ18"/>
    <dbReference type="GeneID" id="39730528"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00200200"/>
    <dbReference type="OMA" id="KEIYIYC"/>
    <dbReference type="OrthoDB" id="25129at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002143">
        <property type="term" value="P:tRNA wobble position uridine thiolation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019407">
        <property type="entry name" value="CTU2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20882">
        <property type="entry name" value="CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20882:SF14">
        <property type="entry name" value="CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="512" mass="60524" checksum="33483E96638C6B17" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ26</accession>
    <name>A0A1J1GQ26_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Gas41 homologue, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00109600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526213.1">
        <property type="nucleotide sequence ID" value="XM_028673721.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ26"/>
    <dbReference type="GeneID" id="39729622"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00109600"/>
    <dbReference type="OMA" id="VKPYHNE"/>
    <dbReference type="OrthoDB" id="16041at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16887">
        <property type="entry name" value="YEATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1970">
        <property type="entry name" value="YEATS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038704">
        <property type="entry name" value="YEAST_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005033">
        <property type="entry name" value="YEATS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055129">
        <property type="entry name" value="YEATS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47573">
        <property type="entry name" value="PROTEIN AF-9 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47573:SF1">
        <property type="entry name" value="PROTEIN AF-9 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03366">
        <property type="entry name" value="YEATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51037">
        <property type="entry name" value="YEATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="YEATS" evidence="5">
        <location>
            <begin position="4"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="221" mass="25881" checksum="F232E38076F2BB7E" modified="2017-02-15" version="1">MESRMQNVKLVKPLVIGTYSFLLSQQEKRKYGNMTHKWTCLLRCPNSSDISLFINKVVFELDPSFIYPKRVYTQPPYEVNEIGWGEFYLQVKIYFADSTLPPVNIMHFVKLNTDSDSTHCPCVVNETYEEIIFKNPTIGLYNKILQSNSTKVAPHKFQEYFIKYDFKEENFTKTYLQFQSKVQEEICDLMSEATLLSKDINEAQQKYFAMKTEMGVSSDDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQC2</accession>
    <name>A0A1J1GQC2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00210000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527518.1">
        <property type="nucleotide sequence ID" value="XM_028670802.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQC2"/>
    <dbReference type="GeneID" id="39730627"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00210000"/>
    <dbReference type="OrthoDB" id="332498at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="334"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="427" mass="50413" checksum="F9AEB7FB06A3417C" modified="2017-02-15" version="1">MIKNIILRCKNNINENLNWKINDVEYKKLKLKWSDKNLSLSIFDINPSNKKNEEKLEIKNMSIIKHITKTKYDFVVLGIGYVDYHKILKSFNRANLVQRKMIDSIHSNLKKVNGQYISIIQQCLLLNIPHFCLGRDRLTELTSIGTAIFSNPKEIFSLLYYFIINSEENAKGKNGIIENEKNKSDKENNLQNISPNFYRALIVENALYLTYNLHATLLKIIKSKYYIPFDNERSSNNSKKKNLKQRILSFFNETTHDQINKLRMQIRKTELYGDFQIPTEKKDISILIICDSVCVDYFYNLIQKKFSVWYNISPFYNELFNLEKKNTYKFTLSLFLFIIAPISWTITFLIKYLYYLWIEYFTKGKVITVGGDVFFKNSQLIDLDDNDMISKNNNDDFLKSLNNNKVEFETVSLLGGLLQWFKNKSRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQI6</accession>
    <name>A0A1J1GQI6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Transmembrane emp24 domain-containing protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00192200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EMP24/GP25L family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000029">
        <property type="protein sequence ID" value="CRG94524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527339.1">
        <property type="nucleotide sequence ID" value="XM_028670603.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQI6"/>
    <dbReference type="GeneID" id="39730447"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00192200"/>
    <dbReference type="OMA" id="MIDFDPE"/>
    <dbReference type="OrthoDB" id="1929172at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015720">
        <property type="entry name" value="Emp24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009038">
        <property type="entry name" value="GOLD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22811">
        <property type="entry name" value="TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01105">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01190">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="314"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="GOLD" evidence="9">
        <location>
            <begin position="169"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="34"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="44"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG94524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="346" mass="41303" checksum="831E4621CEE025A0" modified="2017-02-15" version="1">MKIIYPYYFIFFFFIILCVIDKVSSKARSNNYQNKEKKDDNKNHVNSLNNLNNYDNYENEDILNIKNKKRKGKSKSIEDNLSEFINETKDNSEDSFNEEYNKLEKEFQYNLNENESKSNFEENNLNEEYDKMKPNMEDFHYNDNDEDMDEEDLTNIWNKNMQNFEPSTSLTFEIASNSEEYLFEEINMENTYFRGVFYSNNESDDNIIEFFISDPDGNVVYKKEASEGIFFFYTKKIGIYTITLKNSKWVGKKLTTVALGLGENPSLSSDHVKDFTNYIQEIVHRTKKLKNEIKYLSSKHMIHIEKMKRITNKAFIYCFIKLFVLIFLSLFTIYYIKNLVSNKRVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQJ2</accession>
    <name>A0A1J1GQJ2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00212000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527538.1">
        <property type="nucleotide sequence ID" value="XM_028670824.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQJ2"/>
    <dbReference type="GeneID" id="39730647"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00212000"/>
    <dbReference type="OMA" id="MISIMNK"/>
    <dbReference type="OrthoDB" id="372408at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="149"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="263" mass="31901" checksum="A7D5574EB7C2EC63" modified="2017-02-15" version="1">MNSETKMDNTNMINKLNKEKHEEIIECLKNKDLGKNVFETLENFFLEEKENNKNNYKELYHLINKIKTDFDDKINSLKDNTHENFEELKYYMDELNKNNKENTLDSNSFKDDIDFIKDDLLNLKKQKDENINLIKSSTRTYFDKIKSMLNIMNINIENVKEEITKYKENNEIENKKKYIEILQLINDENEILNKRREESVNYINEEIKQVKEYINGFKESLEKHIKNIEYKIEINKKEIDEKINTISKNQKKFLEDFYPSYKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQY3</accession>
    <name>A0A1J1GQY3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00234800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527764.1">
        <property type="nucleotide sequence ID" value="XM_028671074.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQY3"/>
    <dbReference type="GeneID" id="39730876"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00234800"/>
    <dbReference type="OMA" id="KLPYPVF"/>
    <dbReference type="OrthoDB" id="328978at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="263" mass="30197" checksum="49EAE1ED393B4260" modified="2017-02-15" version="1">MKINLKIFLVTYFIVFLEGYFSISLLSKSVFPREFTKAVEKHLREDYGDRDVAIFREILRNYKNNDVLLSPSEEENLKASMKKYAGSHFIEEYENLMDEKTVDSKRTLAKSMINLIKQQFIKLKEIEAQYVTPNFEQFKQVTELKPEISDLRADTPCSTDAECKKLENMMNICTYIRGGADFAYDIFLVTTHVVTSMMAVLCACIFIGPVHICALKNFPYTCKLPYPVFSTLFMATSAVWEVVKATTALCRVYGDLSVMSKMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR82</accession>
    <name>A0A1J1GR82_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">AP2/ERF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00233500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527751.1">
        <property type="nucleotide sequence ID" value="XM_028671060.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730862"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00233500"/>
    <dbReference type="OrthoDB" id="10538069at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00847">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="8">
        <location>
            <begin position="2033"/>
            <end position="2083"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="482"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2007"/>
            <end position="2026"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1781"/>
            <end position="1816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="482"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2126" mass="249567" checksum="BE28A0AECB5C5B0B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRH4</accession>
    <name>A0A1J1GRH4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ubiquitin-conjugating enzyme E2, putative</fullName>
            <ecNumber evidence="2">6.3.2.19</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00134700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.19" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526464.1">
        <property type="nucleotide sequence ID" value="XM_028674876.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRH4"/>
    <dbReference type="GeneID" id="39729872"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00134700"/>
    <dbReference type="OMA" id="WRAVMKG"/>
    <dbReference type="OrthoDB" id="9973183at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd23812">
        <property type="entry name" value="UBCc_ScPEX4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000089">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBC core" evidence="1">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="152" mass="17344" checksum="D53EB8A3F06FCCBC" modified="2017-02-15" version="1">MTKNRLLIESREAKKQADPDIILTHSEHNLHEWQAIIKGPRDSPYEGGKWKLNIKCKSTYPIDPPLITFETKFFHPNVNFATGELCMDILKANWSPAWTIQSLCRAILFLFTEPNAESPLNCDAGNLIRSGDIKGFQSMAKMYTVEYAIQND</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRM3</accession>
    <name>A0A1J1GRM3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-directed RNA polymerase, alpha subunit, putative</fullName>
            <ecNumber evidence="5">2.7.7.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00232200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527739.1">
        <property type="nucleotide sequence ID" value="XM_028671047.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRM3"/>
    <dbReference type="GeneID" id="39730849"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00232200"/>
    <dbReference type="OMA" id="CEDRCEF"/>
    <dbReference type="OrthoDB" id="360088at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.12">
        <property type="entry name" value="DNA-directed RNA polymerase, insert domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="entry name" value="RNA polymerase, RBP11-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011262">
        <property type="entry name" value="DNA-dir_RNA_pol_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011263">
        <property type="entry name" value="DNA-dir_RNA_pol_RpoA/D/Rpb3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036643">
        <property type="entry name" value="RNApol_insert_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01000">
        <property type="entry name" value="RNA_pol_A_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00662">
        <property type="entry name" value="RPOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56553">
        <property type="entry name" value="Insert subdomain of RNA polymerase alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="RBP11-like subunits of RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 5" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase RpoA/D/Rpb3-type" evidence="4">
        <location>
            <begin position="393"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="90"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="717"/>
            <end position="745"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="766" mass="91783" checksum="C1AD055F090CC7D4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRV4</accession>
    <name>A0A1J1GRV4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Inner membrane complex protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00256700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527975.1">
        <property type="nucleotide sequence ID" value="XM_028671309.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRV4"/>
    <dbReference type="GeneID" id="39731095"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00256700"/>
    <dbReference type="OMA" id="FSNFERH"/>
    <dbReference type="OrthoDB" id="390329at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="368" mass="43516" checksum="4EBB9843848DE3C7" modified="2017-02-15" version="1">MNKLENNLDETNDTLVESGCRTYIMEGYPTENGETQPELKEYYVYPNVVVHDYENNNNSLMNFDCSKTPFSCHPKNPRVFIRRVDNKRIWGNKTYNVLNGSYYKNVSHPIFPSRDSFDRRKMEEHNYSMNANESGGINENYLSNKINDKTYMYATDEYNYPINEQVLNDSNIQMDVPLCVQEASQSDNGYNIVLPINPINQDEYYYNYLNPEVLDNKCNINPRAVANFVYIFFKYIYKVFKLALEKIKRDFNTKEVYFDSGMLPFHDLDIACEICRSKYGDILMEAHNKDCLTYFEGYDETRTVFTKLWDILNNWIDSRDNSKIEIIRGKKSINNEAYYQMEDFPKDKNGKIELPEFKPAERKKSVKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRZ4</accession>
    <name>A0A1J1GRZ4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">1-cys-glutaredoxin-like protein-1, putative</fullName>
            <ecNumber evidence="7">1.11.1.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">GLP1</name>
        <name evidence="7" type="ORF">PGAL8A_00003800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.15" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528084.1">
        <property type="nucleotide sequence ID" value="XM_028671431.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRZ4"/>
    <dbReference type="SMR" id="A0A1J1GRZ4"/>
    <dbReference type="GeneID" id="39728560"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00003800"/>
    <dbReference type="OMA" id="WPYIPHL"/>
    <dbReference type="OrthoDB" id="415696at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03028">
        <property type="entry name" value="GRX_PICOT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033658">
        <property type="entry name" value="GRX_PICOT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004480">
        <property type="entry name" value="Monothiol_GRX-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00365">
        <property type="entry name" value="Grx4 family monothiol glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293">
        <property type="entry name" value="GLUTAREDOXIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293:SF72">
        <property type="entry name" value="MONOTHIOL GLUTAREDOXIN-S14, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="5" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="6">
        <location>
            <begin position="83"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="168" mass="19924" checksum="A0017C8BB770CB07" modified="2017-02-15" version="1">MITKNNFGFLFFLRRNAMNKNVKFSSLIKFSKINLFNSFSDEKNGTFENKIDQNKKECIEFEKSDIYMTLRTKIKEVLEKEKIVLFMKGSPEKPLCGFSANVVYILNHMNVKDYVYIDVMKNQNLREAIKIYSNWPYIPHLYVRNNFIGGYDIISELYNKGELEKILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS73</accession>
    <name>A0A1J1GS73_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00256100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527969.1">
        <property type="nucleotide sequence ID" value="XM_028671303.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS73"/>
    <dbReference type="GeneID" id="39731089"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00256100"/>
    <dbReference type="OMA" id="KTCCICH"/>
    <dbReference type="OrthoDB" id="371074at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="2">
        <location>
            <begin position="238"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="331" mass="39215" checksum="3FE8382E3786E622" modified="2017-02-15" version="1">MQNNEHFKKKDIDLSDVKLEKFKKAAFEVIEYKDKIIRMLCAILEVQGTTTLNIKEFISNATDVTNDNLFMNNEYELKANKKKTSSRKRTLINIPDFRTIKKNKELNLFSTPNKINEELNKENHFSDSILSSYKLSLKEKNYENKIIDNNLKCNFSEKKNLQEQIVNSSQKKNENSWNTLQKKNDGFVKNILESHRKALENFRNNEANFECTYKSDSQMDIKTSKNTPKIKETINEECQLCLMPNTESLHGNFPPIFYKLNCDHVFHLMCLYEIIIRRECRKTCCICHNELDEEDKDNIIRRVKREKKENDKKSKLLFKVMKLQSNNKNQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS79</accession>
    <name>A0A1J1GS79_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Calcium-dependent protein kinase 3</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="primary">CDPK3</name>
        <name evidence="23" type="ORF">PGAL8A_00009400</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Calcium-dependent protein kinase which acts as a sensor and effector of intracellular Ca(2+) levels probably in part downstream of cGMP-activated PKG kinase. In the mosquito midgut, regulates the gliding motility of the ookinete which is essential for the ookinete to invade the midgut epithelium. However, another study showed that while required for ookinete invasion of the midgut epithelium, is not required for ookinete gliding motility.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528138.1">
        <property type="nucleotide sequence ID" value="XM_028671491.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS79"/>
    <dbReference type="GeneID" id="39728616"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00009400"/>
    <dbReference type="OMA" id="YGESDHE"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05117">
        <property type="entry name" value="STKc_CAMK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000315">
        <property type="entry name" value="Calcium-dependent protein kinase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000003">
        <property type="entry name" value="Calmodulin A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000739">
        <property type="entry name" value="CAMK/CDPK protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050205">
        <property type="entry name" value="CDPK_Ser/Thr_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24349">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 23" id="KW-0418">Kinase</keyword>
    <keyword evidence="13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="21">
        <location>
            <begin position="110"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="22">
        <location>
            <begin position="410"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="22">
        <location>
            <begin position="480"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="22">
        <location>
            <begin position="521"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00024334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00057374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00068068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="CRG95327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="554" mass="63702" checksum="48B90D9F123562B0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSJ2</accession>
    <name>A0A1J1GSJ2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00398400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527101.1">
        <property type="nucleotide sequence ID" value="XM_028670339.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSJ2"/>
    <dbReference type="GeneID" id="39732514"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00398400"/>
    <dbReference type="OMA" id="FEPCDFN"/>
    <dbReference type="OrthoDB" id="432817at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="628" mass="76044" checksum="63EB0201D46DF666" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GST4</accession>
    <name>A0A1J1GST4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Dynein light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00275300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528364.1">
        <property type="nucleotide sequence ID" value="XM_028671741.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GST4"/>
    <dbReference type="GeneID" id="39731285"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00275300"/>
    <dbReference type="OMA" id="EHNNDMN"/>
    <dbReference type="OrthoDB" id="273640at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019347">
        <property type="entry name" value="Axonemal_dynein_light_chain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10211">
        <property type="entry name" value="Ax_dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="165"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="270" mass="32437" checksum="0B95EF385072D504" modified="2017-02-15" version="1">MEKNHNILKYGNSFNVSKELKSYMLKVMSEYKNYFEKILIKNRNLEDNINFVKDIIIDEENSYNEDIFLKIQKKFHLYDIFNLSFLFPTNILNKNGKTLVQLISEDTNQNDLEVIYAILKNIEQNELDKLNFFYIENIIFELLDEIIRQITVECPKRGFALILINNELQKNINYYKNLIKIIEHNNDVNNGKFKEMQSYYSSLLEHLSVEEKTLKEKLIDLQNEFEILKNENKKKLQENKNKKEIQYDLLKHNESLLEKIKEIYDKNGEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSV1</accession>
    <name>A0A1J1GSV1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00281100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528422.1">
        <property type="nucleotide sequence ID" value="XM_028671806.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSV1"/>
    <dbReference type="GeneID" id="39731344"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00281100"/>
    <dbReference type="OMA" id="QMNIDQN"/>
    <dbReference type="OrthoDB" id="372204at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="152"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="695"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="300"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="404"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="892"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="157"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="701"/>
            <end position="842"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1232" mass="146994" checksum="A01DA57684631E6B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTE7</accession>
    <name>A0A1J1GTE7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">GDP-fructose:GMP antiporter, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00402700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527144.1">
        <property type="nucleotide sequence ID" value="XM_028670386.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTE7"/>
    <dbReference type="GeneID" id="39732557"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00402700"/>
    <dbReference type="OMA" id="WWTSNIV"/>
    <dbReference type="OrthoDB" id="5547497at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="222"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="277"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG94323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="308" mass="36426" checksum="E716E23FE5ED89E0" modified="2017-02-15" version="1">MKKTRLRMFLSIVIYLISSITSVFANKYVLMENVMDTVLLIFLQHVSCLIFLFLFRKYLRKFQDKNNFQDYFFSLYDGIKNMWQLIISFNLTLIFGNICLKYTNVSSYQLARSMTLPFNFLFSYFFFKQIKFNCLMTLSCILVSIGFFVFSIDAINTNYKSVLYGTIVSIIQAIHLNLLKVKLMIYKDKMIMMHYNLIYSSIILFIYLFLTKDIFIIFTLNYRILFFLFLSCISSICVTFSSFLCIYYTDNVVFNMFGNVKSTIQTFLSKFYYSEKFNLNTVIGIILTTIGSFIYTCSSEYAKKEKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU15</accession>
    <name>A0A1J1GU15_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Apicoplast ribosomal protein S10, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00220300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527621.1">
        <property type="nucleotide sequence ID" value="XM_028670916.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU15"/>
    <dbReference type="GeneID" id="39730730"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00220300"/>
    <dbReference type="OMA" id="GCKLDIF"/>
    <dbReference type="OrthoDB" id="366214at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.600">
        <property type="entry name" value="Ribosomal protein S10 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00508">
        <property type="entry name" value="Ribosomal_uS10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001848">
        <property type="entry name" value="Ribosomal_uS10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027486">
        <property type="entry name" value="Ribosomal_uS10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036838">
        <property type="entry name" value="Ribosomal_uS10_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11700">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S10 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00338">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01403">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54999">
        <property type="entry name" value="Ribosomal protein S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS10" evidence="4">
        <location>
            <begin position="74"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="272" mass="33091" checksum="94268F5E5678EA0E" modified="2017-02-15" version="1">MSFYAFIIFLTIYYTYNIGYSFKLKLKTSITFLNGYKKNTLKKSSKLYNNLEKVNNDLKKEDIIKKWSDNYHLRIILNSYFSDHLQKAVLNVKEKINQYPQFNIVGPIPQKTIKKRFTFLRSPHVDKDSREQFEIRQYGCKLDIYLNSSISLKNSEFVSFLSVKLPRFVGFEYYFEENYKGLTKKEINSLKKKKYVNKYYKNLFDSTEKKKYVDLLLENSKYMNVKLPRNFYDLYKYPLDILRHFYKKTMEKKKWYHENEELMKKIESLSFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU83</accession>
    <name>A0A1J1GU83_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fam-h protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00325600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000053">
        <property type="protein sequence ID" value="CRG96042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528850.1">
        <property type="nucleotide sequence ID" value="XM_028672282.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU83"/>
    <dbReference type="GeneID" id="39731788"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00325600"/>
    <dbReference type="OMA" id="MISFMIC"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="185" mass="21772" checksum="62EE00CA5A5A3711" modified="2017-02-15" version="1">MNSLFFSIKYLMFAFLILILQYSNNSSFESWNIKKNSEGAFRLKVKRTLSENIFKKSKSESTENLLYAYEKEEINEKQDEKEKDITKSNTQKSIFHSNIIPKSSETKVEISNENSVSKKKVSKCKDKFIRTLAFSLAFLSLPLYLVYLSHMAAFFNWDKHKKTSLIIMSYCILMISFMICLLFRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUT1</accession>
    <name>A0A1J1GUT1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00345500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529042.1">
        <property type="nucleotide sequence ID" value="XM_028672495.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUT1"/>
    <dbReference type="GeneID" id="39731985"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00345500"/>
    <dbReference type="OMA" id="FLGGPCI"/>
    <dbReference type="OrthoDB" id="282383at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39767">
        <property type="entry name" value="CALCIUM/CALMODULIN-BINDING MEMBRANE PROTEIN PCM4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39767:SF2">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="248" mass="29075" checksum="B124BA70AEB2BCF0" modified="2017-02-15" version="1">MNIFYHISFFLEILLFFTNYVYSNYNIKTNKLIFEDKTEQCKKSIYLYGEKESFIIASKDNVYLEIQDNKTIINSLNIYGKLHTNDFLFFENKQWKLFHLNTFDVNDNSWIPSEISTCRNSPDSFLGGPCKFGATEAYTKINNLPYHKKLNIKLRVHFFDKWDNDSLFLQVDNKTMWTQSHELCPEGNCLLGIDVCGQNHPDRLSVPIDIQFQHSSDTLNILIGSTLKKTTDPCLTSWGVDDFMIYYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUU6</accession>
    <name>A0A1J1GUU6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00329000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000057">
        <property type="protein sequence ID" value="CRG96076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528881.1">
        <property type="nucleotide sequence ID" value="XM_028672317.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUU6"/>
    <dbReference type="GeneID" id="39731819"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00329000"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009618931" evidence="2">
        <location>
            <begin position="29"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="253" mass="30582" checksum="15F3FB8564D5BB13" modified="2017-02-15" version="1">MKTLTLYLKITTFLLLIWMYQCFYNCDSYKTLIDKNILQKKNELKYERVLAEGDIAGKKRTYSEGCLEECPLDNKKNKWENPVQYENPCDYWNKVITPQLWEQFNQETSDMDTKLKEKKWNVEWNKTAANKVNDLSSISRRRDISDEEKKKLIDSVKESLLLEFKKFLDECRKEMRENKTESEFNKGMRDNKTESEYNKEMSDNKTESEFMKEMKQNEAESKSKKEQGKNKKKNKIFDFMKQLIFYKYDNIFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUW2</accession>
    <name>A0A1J1GUW2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">CCR4-NOT transcription complex subunit 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">NOT2</name>
        <name evidence="6" type="ORF">PGAL8A_00355500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CNOT2/3/5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529142.1">
        <property type="nucleotide sequence ID" value="XM_028672606.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUW2"/>
    <dbReference type="GeneID" id="39732085"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00355500"/>
    <dbReference type="OMA" id="LRNTHAV"/>
    <dbReference type="OrthoDB" id="25391at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030015">
        <property type="term" value="C:CCR4-NOT core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.1020">
        <property type="entry name" value="CCR4-NOT complex subunit 2/3/5, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038635">
        <property type="entry name" value="CCR4-NOT_su2/3/5_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040168">
        <property type="entry name" value="Not2/3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007282">
        <property type="entry name" value="NOT2/3/5_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23326">
        <property type="entry name" value="CCR4 NOT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04153">
        <property type="entry name" value="NOT2_3_5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="NOT2/NOT3/NOT5 C-terminal" evidence="5">
        <location>
            <begin position="740"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="163"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="355"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="184"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="355"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="539"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="556"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="911" mass="105952" checksum="B42CF1E865A5CD18" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV13</accession>
    <name>A0A1J1GV13_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00329200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000057">
        <property type="protein sequence ID" value="CRG96078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528883.1">
        <property type="nucleotide sequence ID" value="XM_028672319.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV13"/>
    <dbReference type="GeneID" id="39731821"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00329200"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="263" mass="31420" checksum="858378BDDD6CF4B8" modified="2017-02-15" version="1">MKTLNLYLKISTFLLFIWIYQCFYNSDSYKTLIDENILQTINELKYERILTEGNIEGKKQTYAEGCLEESPLDNKKNKCKNQDQYKDPSNYWNKVIIPQMWKRFDQETSGMDPKLKEKKWNVELHKFSNRKVRDMHLISRRRDISDEEKKQNIDSIMRELHSEFEKFLCKYKKGMGDNKTEFESKKGMTDNKAESESKKGMTDNKTESESKKEMTDNKTECESNKEMKDNKTESESKGDQGKNKKKNKKSNIFKFLFCRFDNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV19</accession>
    <name>A0A1J1GV19_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA repair protein RAD51 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">RAD51</name>
        <name evidence="10" type="ORF">PGAL8A_00334700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the RecA family. RAD51 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528937.1">
        <property type="nucleotide sequence ID" value="XM_028672379.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV19"/>
    <dbReference type="GeneID" id="39731877"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00334700"/>
    <dbReference type="OMA" id="RAYNSNH"/>
    <dbReference type="OrthoDB" id="10251254at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000794">
        <property type="term" value="C:condensed nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070192">
        <property type="term" value="P:chromosome organization involved in meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000730">
        <property type="term" value="P:DNA recombinase assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042148">
        <property type="term" value="P:DNA strand invasion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006312">
        <property type="term" value="P:mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990426">
        <property type="term" value="P:mitotic recombination-dependent replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19513">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000092">
        <property type="entry name" value="DNA repair protein Rad51 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011941">
        <property type="entry name" value="DNA_recomb/repair_Rad51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016467">
        <property type="entry name" value="DNA_recomb/repair_RecA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010995">
        <property type="entry name" value="DNA_repair_Rad51/TF_NusA_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013632">
        <property type="entry name" value="Rad51_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020587">
        <property type="entry name" value="RecA_monomer-monomer_interface"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003301">
        <property type="entry name" value="PRK04301.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02239">
        <property type="entry name" value="recomb_RAD51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22942:SF39">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD51 HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22942">
        <property type="entry name" value="RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08423">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005856">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47794">
        <property type="entry name" value="Rad51 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50163">
        <property type="entry name" value="RECA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecA family profile 1" evidence="8">
        <location>
            <begin position="108"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="RecA family profile 2" evidence="9">
        <location>
            <begin position="286"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG96132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="350" mass="38598" checksum="944FBFEF8217F237" modified="2017-02-15" version="1">MKPANAKEDKLQKVINSNAIDEVEEEQLYTGPLKIEQLLAKGFVKRDLELLKEGGLQTVECVAYAPMRTLCSIKGISEQKAEKLKKACKELCNSGFCNAIDYHDARQNLIKFTTGSKQLDALLKGGIETGGITELFGEFRTGKSQLCHTLAITCQLPIEQSGGEGKCLWIDTEGTFRPERIVAIAKRYGLHPTDCLNNIAYAKAYNCDHQTELLIDASAMMADTRFALLIVDSATALYRSEYIGRGELANRQSHLCRFLRGLQRIADIYGVAVIITNQVVAKVDAMSMFGGHEKIPIGGNIIAHASQTRLYLRKGRGESRICKIYDSPVLPEGEAVFAITEGGIADYEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV69</accession>
    <name>A0A1J1GV69_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein kinase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00334100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528931.1">
        <property type="nucleotide sequence ID" value="XM_028672372.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731871"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00334100"/>
    <dbReference type="OMA" id="HIYCNNI"/>
    <dbReference type="OrthoDB" id="339325at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF140">
        <property type="entry name" value="INACTIVE PROTEIN TYROSINE KINASE PTKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM" evidence="4">
        <location>
            <begin position="283"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="941"/>
            <end position="1289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="482"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="624"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="360"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="199"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="482"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="499"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1307" mass="152990" checksum="185D9DA8EA7C6AE6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV76</accession>
    <name>A0A1J1GV76_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Zinc finger protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00362100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529202.1">
        <property type="nucleotide sequence ID" value="XM_028672673.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732151"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00362100"/>
    <dbReference type="OMA" id="NCEEKIE"/>
    <dbReference type="OrthoDB" id="387309at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045877">
        <property type="entry name" value="ZFP36-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12547">
        <property type="entry name" value="CCCH ZINC FINGER/TIS11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12547:SF18">
        <property type="entry name" value="PROTEIN TIS11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="415"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="450"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="484"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="415"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="450"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="484"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="722"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="734"/>
            <end position="746"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1462" mass="173567" checksum="5A70904259FEF93A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVA0</accession>
    <name>A0A1J1GVA0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Mitochondrial ribosomal protein L11, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00337600</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528963.1">
        <property type="nucleotide sequence ID" value="XM_028672407.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVA0"/>
    <dbReference type="GeneID" id="39731906"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00337600"/>
    <dbReference type="OMA" id="CKQFNAK"/>
    <dbReference type="OrthoDB" id="1091498at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00349">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1550.10:FF:000006">
        <property type="entry name" value="50S ribosomal protein L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.250">
        <property type="entry name" value="Ribosomal protein L11, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="entry name" value="Ribosomal protein L11/L12, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00736">
        <property type="entry name" value="Ribosomal_uL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000911">
        <property type="entry name" value="Ribosomal_uL11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020783">
        <property type="entry name" value="Ribosomal_uL11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036769">
        <property type="entry name" value="Ribosomal_uL11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_uL11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_uL11_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL11M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00298">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00649">
        <property type="entry name" value="RL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="Ribosomal L11/L12e N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46906">
        <property type="entry name" value="Ribosomal protein L11, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0488">Methylation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL11 N-terminal" evidence="9">
        <location>
            <begin position="8"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL11 C-terminal" evidence="8">
        <location>
            <begin position="70"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG96158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="178" mass="20492" checksum="8E160625145404F0" modified="2017-02-15" version="1">MSRIGRFNLIVLAGSAKPSPSIGQTLGPLGINMMTFFKEFNERTKNISKNVPIQVTLEPLNDRTYRFYLRTPSVVWFIRRCARVPMFSSTPKHHIVGSITLAEVFHIAKCKRMDPPLINLSLKSICKYIIGTCNSMGIKVCRELDDESKKKYFVDINKLDNIKKDIRSRNKQQKRSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVL4</accession>
    <name>A0A1J1GVL4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00417500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529398.1">
        <property type="nucleotide sequence ID" value="XM_028672891.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVL4"/>
    <dbReference type="GeneID" id="39732706"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00417500"/>
    <dbReference type="OMA" id="PCVCLIY"/>
    <dbReference type="OrthoDB" id="371404at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="266" mass="32039" checksum="0E3DDABDD366EEEF" modified="2017-02-15" version="1">MLKVLNLNKILKKNNSKFLSVISKNYSTIKNDCMKIDNKYIYNVYKLNESPYNNLKIINNYDEYFNFIIKNEYFKDYSEISNKSHNKIRGETDNKLEEHVSKEIKQQNNTTQNELENIDDETYSKNVIISNDLQVLFFGSYENNISIVLFNKFKSIIEKNKNLNFFFIDINICPQCSYNCQINYVPSVILIYKNHIFRKKFEINYENVVDENYLTEFLNKVQQNIDLFHSYNNKFIYSLEKQSNYLNTKYIDLDNQNIHKENWNTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVL8</accession>
    <name>A0A1J1GVL8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Coatomer subunit gamma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PGAL8A_00372600</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Oligomeric complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 11">Golgi apparatus membrane</location>
            <topology evidence="1 11">Peripheral membrane protein</topology>
            <orientation evidence="1 11">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Cytoplasmic vesicle</location>
            <location evidence="11">COPI-coated vesicle membrane</location>
            <topology evidence="11">Peripheral membrane protein</topology>
            <orientation evidence="11">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the COPG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529306.1">
        <property type="nucleotide sequence ID" value="XM_028672789.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVL8"/>
    <dbReference type="GeneID" id="39732256"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00372600"/>
    <dbReference type="OMA" id="ISKVTWH"/>
    <dbReference type="OrthoDB" id="6537869at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005793">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1480">
        <property type="entry name" value="Coatomer, gamma subunit, appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="entry name" value="TATA-Binding Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013041">
        <property type="entry name" value="Clathrin_app_Ig-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009028">
        <property type="entry name" value="Coatomer/calthrin_app_sub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032154">
        <property type="entry name" value="Coatomer_g_Cpla"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017106">
        <property type="entry name" value="Coatomer_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013040">
        <property type="entry name" value="Coatomer_gsu_app_Ig-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037067">
        <property type="entry name" value="Coatomer_gsu_app_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10261">
        <property type="entry name" value="COATOMER SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10261:SF0">
        <property type="entry name" value="COATOMER SUBUNIT GAMMA-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16381">
        <property type="entry name" value="Coatomer_g_Cpla"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08752">
        <property type="entry name" value="COP-gamma_platf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037093">
        <property type="entry name" value="Coatomer_gamma_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49348">
        <property type="entry name" value="Clathrin adaptor appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55711">
        <property type="entry name" value="Subdomain of clathrin and coatomer appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 11" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6 11" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 11" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="12">
        <location>
            <begin position="37"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer gamma subunit appendage Ig-like subdomain" evidence="13">
        <location>
            <begin position="708"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer subunit gamma C-terminal" evidence="14">
        <location>
            <begin position="860"/>
            <end position="974"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR037093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF16381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG96501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="976" mass="113390" checksum="3A6812636C82B36C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVW5</accession>
    <name>A0A1J1GVW5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Condensin II complex subunit H2 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00020300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CND2 H2 (condensin-2 subunit 2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528245.1">
        <property type="nucleotide sequence ID" value="XM_028671609.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVW5"/>
    <dbReference type="GeneID" id="39728725"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00020300"/>
    <dbReference type="OMA" id="CSRHSTY"/>
    <dbReference type="OrthoDB" id="10038475at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010032">
        <property type="term" value="P:meiotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051306">
        <property type="term" value="P:mitotic sister chromatid separation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031737">
        <property type="entry name" value="CNDH2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009378">
        <property type="entry name" value="H2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031739">
        <property type="entry name" value="Ncaph2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14324">
        <property type="entry name" value="CONDENSIN-2 COMPLEX SUBUNIT H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14324:SF3">
        <property type="entry name" value="CONDENSIN-2 COMPLEX SUBUNIT H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16858">
        <property type="entry name" value="CNDH2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06278">
        <property type="entry name" value="CNDH2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Condensin II complex subunit H2 N-terminal" evidence="4">
        <location>
            <begin position="12"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="Condensin-2 complex subunit H2 C-terminal" evidence="5">
        <location>
            <begin position="522"/>
            <end position="609"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="667" mass="79944" checksum="5C53ABAB5A5C1E69" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW19</accession>
    <name>A0A1J1GW19_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00374100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529321.1">
        <property type="nucleotide sequence ID" value="XM_028672805.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW19"/>
    <dbReference type="GeneID" id="39732271"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00374100"/>
    <dbReference type="OMA" id="HCLLTVY"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24115:SF1004">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KIF15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24115">
        <property type="entry name" value="KINESIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="3 4" id="KW-0505">Motor protein</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="6">
        <location>
            <begin position="4"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="589"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="95"/>
            <end position="102"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="782" mass="92196" checksum="936F3634BA20405C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWN5</accession>
    <name>A0A1J1GWN5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">CHY-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00443300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529655.1">
        <property type="nucleotide sequence ID" value="XM_028673175.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWN5"/>
    <dbReference type="GeneID" id="39732966"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00443300"/>
    <dbReference type="OMA" id="SNHECDI"/>
    <dbReference type="OrthoDB" id="411372at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008913">
        <property type="entry name" value="Znf_CHY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037274">
        <property type="entry name" value="Znf_CHY_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161219">
        <property type="entry name" value="CHY zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51266">
        <property type="entry name" value="ZF_CHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CHY-type" evidence="7">
        <location>
            <begin position="848"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="302"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="495"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="393"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="602"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="311"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="500"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="959" mass="113462" checksum="F0CB28E5A43E0204" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWU3</accession>
    <name>A0A1J1GWU3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00430700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529531.1">
        <property type="nucleotide sequence ID" value="XM_028673038.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWU3"/>
    <dbReference type="GeneID" id="39732839"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00430700"/>
    <dbReference type="OMA" id="NFFYQYL"/>
    <dbReference type="OrthoDB" id="376063at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="433" mass="51678" checksum="8C5A6AFD32222B06" modified="2017-02-15" version="1">MNIEKLTADLNDIENEFNEENKGGDFLCLNMFKLDNCTMPYENVINYFSIFNIKNEYKKTEINAEKIQISILNNLIFLLNLKKKFYDEEILKIILECINVSFKNKNETIENASEEKSLLIYKQHLLKNKYLFLKILRKIKSKNYYPDIKQCIKDVTRDVFSFNMSVYNGSLGFETILFLLYKLLNKNLKNDIRNFLLSFFLLSIMSRTNNSVDILYILEYFYKNNNFSLIIPNTSYLTPCEVSIYNNIIILKTNVKYFINLIDQTNLSYNCHNIIYIDENLISDNFYLYIYKTLLKQKKYHYIFNNKTFENLDFFNINMNYSKLKGSNINCEENLNVKIKKENTINVEHISDQKEHNLINKENINEKIKNGAIIEFPTEDIEIFSDSTYSVSDNEFDIKKINEQNSYYLNIDNNSNKKKKNYFYQYLIIELNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWW5</accession>
    <name>A0A1J1GWW5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00271200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000041">
        <property type="protein sequence ID" value="CRG95511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528320.1">
        <property type="nucleotide sequence ID" value="XM_028671693.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWW5"/>
    <dbReference type="GeneID" id="39731243"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00271200"/>
    <dbReference type="OrthoDB" id="10583799at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012837005" evidence="2">
        <location>
            <begin position="20"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="326" mass="38343" checksum="411F6D9678A79927" modified="2017-02-15" version="1">MFMLFSVFLPLSPIDLLTGYSCDSYKTLIYKNILQKKNKLKYERGLTEGDIAAKNQAYAEGYPEECPLDNKKNNCEDPFQYENPCDHWHNVIAPKMLELFNKVTSGMDPNLKEKKWNNEWNKISANHVKDLSSISHRQDISEEEKKKLIDSVMEKRLSEFLKFLDACEEMMRDHKTRSECKKEMRDNKIKSKCKKEMRDNKTKSESMKEIRENKTESKGKKVMRDNKTEFESKKEMIDNKRESESMNEMIDNKTESESKKGMIDNKTECESKNKMTDNKTESESKNEIIDNKTESQSKNEIIDNKTESESKNEMTDYKTCPHSFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX30</accession>
    <name>A0A1J1GX30_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cytochrome c oxidase assembly protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00306500</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>Fe(II)-heme o + 2 A + H2O = Fe(II)-heme a + 2 AH2</text>
            <dbReference type="Rhea" id="RHEA:63388"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:60530"/>
            <dbReference type="ChEBI" id="CHEBI:61715"/>
            <dbReference type="EC" id="1.17.99.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:63389"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="10">Porphyrin-containing compound metabolism; heme A biosynthesis; heme A from heme O: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528661.1">
        <property type="nucleotide sequence ID" value="XM_028672071.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX30"/>
    <dbReference type="GeneID" id="39731598"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00306500"/>
    <dbReference type="OMA" id="WLNFLAN"/>
    <dbReference type="OrthoDB" id="1726137at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120547">
        <property type="term" value="F:heme A synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016653">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006784">
        <property type="term" value="P:heme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003780">
        <property type="entry name" value="COX15/CtaA_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023754">
        <property type="entry name" value="HemeA_Synthase_type2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23289">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23289:SF2">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02628">
        <property type="entry name" value="COX15-CtaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="216"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="280"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="350"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="378"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="404"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG95853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="430" mass="51023" checksum="1093ED3DAE004B50" modified="2017-02-15" version="1">MYFNRIFQNYHIQKNFGNVLKRRILFNKNYVSTFNKLNKVEELYILKKVEKCKNLVKEGYEFKVGIWLNTCSLLILGMISIGGYTRLTESGLSITHWKFQGIKYPRSNEEWMEEFEKYKMTPEYKEVHYNISLDEYKKIFFNEWLHRMFGRGIGLFFVSGAGYFLFKRSLKKNMIKKLSFVLTLGIFQGLVGWWMVKSGFHKPETENKTPRVSPYRLVFHLLCATVTYSYTFVNSLTLIELGKLRRQFKKSKLSSWSEFLRNELIHGMYEKRNITKKMKLGLFAFTLLTFSNILYGGFVAGNDAGYAYNTWPKMLDKFVPDDVRNFYMQKKKKYKQLFENTAVVQFNHRMLSYIIVLNSFLLYYYSKTLSLSKKTRRFFFLLPIITTTQMLTGISVVIHHVPIYLALVHQFGGFCVLSTLLHLLKRIYMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX39</accession>
    <name>A0A1J1GX39_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Vacuolar protein sorting-associated protein 26, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">VPS26</name>
        <name evidence="4" type="ORF">PGAL8A_00471200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529934.1">
        <property type="nucleotide sequence ID" value="XM_028673486.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX39"/>
    <dbReference type="GeneID" id="39733245"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00471200"/>
    <dbReference type="OMA" id="FKWKFSS"/>
    <dbReference type="OrthoDB" id="3821113at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030904">
        <property type="term" value="C:retromer complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.640:FF:000015">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028934">
        <property type="entry name" value="Vps26-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12233">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING 26 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03643">
        <property type="entry name" value="Vps26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="297" mass="34605" checksum="94672B3FBCD0ADC5" modified="2017-02-15" version="1">MLSNIFGSVCSINLNIDAEENRKFAFLRKDKKGERCPIFSDGEDINGTATISLKPGKKFEHYGIKLELIGQINILNDKTNSYDFFSMSKDLEPPGLLIESKQFKWKFSSVDKQHESYFGVNVQLRYFVRLNIIKGYSGNIQKEMDFIVQNLSIPPEINNTIKMEVGIEDCLHIEFEYDKSKYHLKDVVVGKVYFLLVRIKIKHMELDIIKMETSGVGKNYTTESITLSKFEIMDGSPTKSECIPVRLYLSGFDLTPTYKNIQNKFSVKYYINLIIVDEEERRYFKKQEIFLWRKKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX52</accession>
    <name>A0A1J1GX52_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Plasmepsin IV</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">PM4</name>
        <name evidence="18" type="ORF">PGAL8A_00279700</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Vacuole lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528408.1">
        <property type="nucleotide sequence ID" value="XM_028671791.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX52"/>
    <dbReference type="GeneID" id="39731330"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00279700"/>
    <dbReference type="OMA" id="KYDHDAS"/>
    <dbReference type="OrthoDB" id="771136at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020020">
        <property type="term" value="C:food vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005775">
        <property type="term" value="C:vacuolar lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000035">
        <property type="entry name" value="Plasmepsin-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000038">
        <property type="entry name" value="Plasmepsin-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 15" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="12 14" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 15" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="17">
        <location>
            <begin position="138"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="active site" evidence="13">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <feature type="active site" evidence="13">
        <location>
            <position position="336"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="169"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="14">
        <location>
            <begin position="371"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="CRG95600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="450" mass="51492" checksum="A6B914F94EEF8F3D" modified="2017-02-15" version="1">MDITIKEQDYSNSLIKSTSAFERLKANNLKFFKFQKKLRILYLVLFILLTGAFAFFLVENYYFSNNKLNEVLQNTEYLTIAVKIERSQEKVLKTLINKKLKNYIKETFKFLNSGYLTENYLGNENDSVELDEVSNVMFYGEAEVGDDKQKFTFIFDTGSANLWVPSTKCSSKGCTTKHIYDSSKSKTYEEDGEKAEITYGSGSIKGFFSKDLVTIGHLSLPYKFIEVTDTDDLEPIYSSSPFDGIVGLGWKDLALGKISPIVVELKNQNKIDHGLFTFYLPVLDKHAGYLTIGGIEDKFYEGEITYEKLNHDLFWQIDLDITFGNDTFEKANAIIDSGTSTIVAPTEFVKKFFKDAGIFKVPFLPVYVTECDNKSLPTLEFHSGNNKYTLEPKFYLDTLEEVDESLCMVYIMPGDIDKQTFILGDPFMRKYFTVFDYDNERVGFAVAKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX56</accession>
    <name>A0A1J1GX56_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rab GDP dissociation inhibitor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00463500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Rab GDI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529858.1">
        <property type="nucleotide sequence ID" value="XM_028673402.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX56"/>
    <dbReference type="GeneID" id="39733168"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00463500"/>
    <dbReference type="OMA" id="FETKAKM"/>
    <dbReference type="OrthoDB" id="9446342at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005093">
        <property type="term" value="F:Rab GDP-dissociation inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.405.10:FF:000011">
        <property type="entry name" value="Rab GDP dissociation inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.405.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.519.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018203">
        <property type="entry name" value="GDP_dissociation_inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000806">
        <property type="entry name" value="RabGDI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787:SF8">
        <property type="entry name" value="RAB GDP DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787">
        <property type="entry name" value="RAB GDP-DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00996">
        <property type="entry name" value="GDI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00892">
        <property type="entry name" value="RABGDI"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00891">
        <property type="entry name" value="RABGDIREP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="457" mass="52212" checksum="B781946CB0381DCF" modified="2017-02-15" version="1">MNEHYDVIILGTGLKECILSGLLSHYGKKILVLDRNPYYGGETASLNLTNLYNTFKPDEKIPSKYGENRHWNVDLIPKFILVGGNLVKILKKTRVTNYLEWLVVEGSYVYQHQKKGLLYSEKFIHKVPATDMEALVSPLLSLMEKNRCKNFYQYVSEWDSNNKSTWKNLDPFKLTMMDIYKYFNLCQLTIDFLGHAVALYLNDDYLKEPAYVTLERIKLYMQSISAFGKSPFIYPLYGLGGIPEGFSRMCAINGGTFMLNKNAVDFIFNDNKVCGIKSSDGEVAYCDKVICDPSYVMHLENKIKKIGQVIRCICILSNPIPETNQANSCQIIIPQNQLNRKSDIYINLVSFQHGVTLKGKYIAIVSATVETDNPLKEIEKPLELLGSIEEKFVKISDIYTSIDKKPEDNIFVTSSYDATSHFETATNDLLQIWENLWGQKLNFDDLATNEENEGELQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX93</accession>
    <name>A0A1J1GX93_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PGAL8A_00467600</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529898.1">
        <property type="nucleotide sequence ID" value="XM_028673447.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX93"/>
    <dbReference type="GeneID" id="39733209"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00467600"/>
    <dbReference type="OMA" id="GELPFNN"/>
    <dbReference type="OrthoDB" id="63267at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05123">
        <property type="entry name" value="STKc_AGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000008">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000524">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045270">
        <property type="entry name" value="STKc_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24351">
        <property type="entry name" value="RIBOSOMAL PROTEIN S6 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 14" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="358"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="13">
        <location>
            <begin position="616"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="387"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG97095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="683" mass="81152" checksum="7711636EC90D0314" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXI0</accession>
    <name>A0A1J1GXI0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pantothenate kinase, putative</fullName>
            <ecNumber evidence="4">2.7.1.33</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">PANK</name>
        <name evidence="4" type="ORF">PGAL8A_00292400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.33" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528528.1">
        <property type="nucleotide sequence ID" value="XM_028671924.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXI0"/>
    <dbReference type="GeneID" id="39731457"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00292400"/>
    <dbReference type="OMA" id="DEMNCIM"/>
    <dbReference type="OrthoDB" id="498611at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004594">
        <property type="term" value="F:pantothenate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.510">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004567">
        <property type="entry name" value="Type_II_PanK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12280:SF20">
        <property type="entry name" value="4'-PHOSPHOPANTETHEINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12280">
        <property type="entry name" value="PANTOTHENATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03630">
        <property type="entry name" value="Fumble"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="600" mass="69545" checksum="4F0ACA5C39FE185A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXN6</accession>
    <name>A0A1J1GXN6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00298800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528584.1">
        <property type="nucleotide sequence ID" value="XM_028671986.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731521"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00298800"/>
    <dbReference type="OrthoDB" id="370839at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044986">
        <property type="entry name" value="KIF15/KIN-12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37739">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KIN-12D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37739:SF14">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KIN-12E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0493">Microtubule</keyword>
    <keyword evidence="5" id="KW-0505">Motor protein</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1150"/>
            <end position="1430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1461" mass="174438" checksum="922903B88B9D9292" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXP0</accession>
    <name>A0A1J1GXP0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein phosphatase inhibitor 3, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">I3</name>
        <name evidence="2" type="ORF">PGAL8A_00491100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530134.1">
        <property type="nucleotide sequence ID" value="XM_028673708.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXP0"/>
    <dbReference type="GeneID" id="39733444"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00491100"/>
    <dbReference type="OMA" id="MSHMHSS"/>
    <dbReference type="OrthoDB" id="307488at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008157">
        <property type="term" value="F:protein phosphatase 1 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004865">
        <property type="term" value="F:protein serine/threonine phosphatase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011107">
        <property type="entry name" value="PPI_Ypi1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20835:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE PPP1R11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20835">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE PPP1R11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07491">
        <property type="entry name" value="PPI_Ypi1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0650">Protein phosphatase inhibitor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="111" mass="12682" checksum="49F857B07A9E4F59" modified="2017-02-15" version="1">MMSHMHSSSTTTYIQEPNTKNDQNGNASTIVRILKLSPQKMVRWDENTIDNENAKKKSSKICCIYHKPREFGESSDSNSDSDSSDIEHNCNSCSKKDNHKNETKEEKELKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXR2</accession>
    <name>A0A1J1GXR2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Chromodomain-helicase-DNA-binding protein 1 homolog, putative</fullName>
            <ecNumber evidence="11">3.6.4.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">CHD1</name>
        <name evidence="11" type="ORF">PGAL8A_00483200</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="11"/>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530055.1">
        <property type="nucleotide sequence ID" value="XM_028673620.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733365"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00483200"/>
    <dbReference type="OMA" id="KQSMGGI"/>
    <dbReference type="OrthoDB" id="5857104at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034728">
        <property type="term" value="P:nucleosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623:SF14">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Chromo" evidence="8">
        <location>
            <begin position="1012"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="domain" description="Chromo" evidence="8">
        <location>
            <begin position="1094"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="1199"/>
            <end position="1375"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="1508"/>
            <end position="1664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="384"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="530"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="787"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="953"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1990"/>
            <end position="2085"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2117"/>
            <end position="2177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2394"/>
            <end position="2537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2550"/>
            <end position="2602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2798"/>
            <end position="2840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="530"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="544"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="794"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="955"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="974"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1998"/>
            <end position="2015"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="2016"/>
            <end position="2034"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="2068"/>
            <end position="2085"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="2121"/>
            <end position="2136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="2137"/>
            <end position="2155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="2399"/>
            <end position="2409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="2431"/>
            <end position="2443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="2453"/>
            <end position="2472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="2475"/>
            <end position="2488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="2509"/>
            <end position="2525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="2526"/>
            <end position="2537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="2552"/>
            <end position="2561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="2567"/>
            <end position="2576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="2577"/>
            <end position="2590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="2806"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="2831"/>
            <end position="2840"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG97253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2840" mass="329510" checksum="0B36302A5E9A1823" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXS8</accession>
    <name>A0A1J1GXS8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Uroporphyrinogen-III synthase</fullName>
            <ecNumber evidence="1">4.2.1.75</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00468300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>hydroxymethylbilane = uroporphyrinogen III + H2O</text>
            <dbReference type="Rhea" id="RHEA:18965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57308"/>
            <dbReference type="ChEBI" id="CHEBI:57845"/>
            <dbReference type="EC" id="4.2.1.75"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 3/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the uroporphyrinogen-III synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.75" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529905.1">
        <property type="nucleotide sequence ID" value="XM_028673454.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXS8"/>
    <dbReference type="GeneID" id="39733216"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00468300"/>
    <dbReference type="OMA" id="TKINCYD"/>
    <dbReference type="OrthoDB" id="386028at2759"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004852">
        <property type="term" value="F:uroporphyrinogen-III synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006780">
        <property type="term" value="P:uroporphyrinogen III biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10090">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036108">
        <property type="entry name" value="4pyrrol_syn_uPrphyn_synt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039793">
        <property type="entry name" value="UROS/Hem4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38042">
        <property type="entry name" value="UROPORPHYRINOGEN-III SYNTHASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38042:SF1">
        <property type="entry name" value="UROPORPHYRINOGEN-III SYNTHASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69618">
        <property type="entry name" value="HemD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="395" mass="46775" checksum="E4A57C28A83262F9" modified="2017-02-15" version="1">MEINLLKYIFFFLIYIISSVCYKLRNFLSDSFLKLNNIKTNRNILKYNKEVNPSSKKWSLKYNENITLLKNEEKEKLYVLITSPEGARIYRFLVILFIYNLKREQNCKSFEILMDNHRYVSEILKIPIISIGESCNKILNNEFKKSDFFNIYKNISLENKKEIIDNDIFNKINNDIGKLNIVFYPSKSNSTVLKKELICKFFNNTQITNANLVWISSAISNSNFNELSLLNKKKNNKIEKNIRVTKINCYDTKKVVYKKENNINKNSIICLMSNSTALSFYENFGNDFDYVICMGISCYKLLKKLNFKNVYFPEDSKTHSFLNILVNLYNKLKNGYKKEFQVVLTREKDKNEELKRILSELNIPLKIIPCTKTKYNFENIKNVYSLIYSYIKNQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXY2</accession>
    <name>A0A1J1GXY2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcription factor with AP2 domain(S), putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ApiAP2</name>
        <name evidence="3" type="ORF">PGAL8A_00335100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528941.1">
        <property type="nucleotide sequence ID" value="XM_028672383.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731881"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00335100"/>
    <dbReference type="OrthoDB" id="372841at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2050">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1201"/>
            <end position="1221"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="281"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="15"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1201"/>
            <end position="1212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1411" mass="161936" checksum="7A2102696CCD45F5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY03</accession>
    <name>A0A1J1GY03_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Calmodulin binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00337800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528965.1">
        <property type="nucleotide sequence ID" value="XM_028672409.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY03"/>
    <dbReference type="GeneID" id="39731908"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00337800"/>
    <dbReference type="OMA" id="QRGVYNY"/>
    <dbReference type="OrthoDB" id="190375at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="201" mass="24923" checksum="DBD58D2D793467FA" modified="2017-02-15" version="1">MMFIKLSKYMNIFYEYKALLREKKENEKREKLAAIVIQKYYRGYKERRAYLIYKYFIKYIKHKIQLCSCKYLLKNLKKQKLEQQMIMYMSDNAIKIQKTFRGFYSRKYIHDFFKRKRQIIEIDNYVNEKKSKMLLELEEKRKKQLIYENKLKDMKIHKVAKNLHHLVSTKAQRGVYNLKIENIIKEQQGKIEKKDKNYTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY35</accession>
    <name>A0A1J1GY35_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00495200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530175.1">
        <property type="nucleotide sequence ID" value="XM_028673753.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY35"/>
    <dbReference type="GeneID" id="39733485"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00495200"/>
    <dbReference type="OMA" id="DHKEIQF"/>
    <dbReference type="OrthoDB" id="1668230at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="220" mass="26690" checksum="E4D1C38CFD01EB9A" modified="2017-02-15" version="1">MLSRVFLWNRVSCSLSFIPMRAPTKKKNIQEKKKKEDTDEKEKLSETRYLPYIPPAYVVDTVSFFKDKNKLDNLLSLIFSPKNSTDSYEDRVEYQKNFEIYQILKEKEENKYEKHLERMKEKIFKSIENLPEELYDESIKRGDLLDNKEIQFGLKYENDLVKNMNVYKKKLLHVYKILLYLRYPFYLIKRKNPLLFYISESKAISRQKQINSQKKKLKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY67</accession>
    <name>A0A1J1GY67_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00498000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000102">
        <property type="protein sequence ID" value="CRG97405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530207.1">
        <property type="nucleotide sequence ID" value="XM_028673790.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY67"/>
    <dbReference type="GeneID" id="39733513"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00498000"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006496">
        <property type="entry name" value="CHP01606_Plasmodium_spp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09688">
        <property type="entry name" value="Wx5_PLAF3D7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012588409" evidence="2">
        <location>
            <begin position="29"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="211" mass="25290" checksum="0C169C57E2E64818" modified="2017-02-15" version="1">MKTLTLYLKITTLLLLIWMYQRFYNCDSYKTLIDKNILLTKNELIYERVLTEGDIAGKKQNNAGGCLEERPLGNKKNKCKNPAQYKNPCDQWHRVITPALWERFNKETIEMDPKWRNQKWNSEWNKISANKVNDLRSMSCRRDIPDEEKNKITDSIIKELESEFEKFLCECKQEMRDHKTESESKKEQGKNKIKNKESNIFKFLFSKFHNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY93</accession>
    <name>A0A1J1GY93_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">W2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00346600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529053.1">
        <property type="nucleotide sequence ID" value="XM_028672507.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY93"/>
    <dbReference type="GeneID" id="39731996"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00346600"/>
    <dbReference type="OMA" id="PKRVIMY"/>
    <dbReference type="OrthoDB" id="445594at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070274">
        <property type="term" value="C:RES complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11473">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051112">
        <property type="entry name" value="CWC26_splicing_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003307">
        <property type="entry name" value="W2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31809">
        <property type="entry name" value="BUD13 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31809:SF0">
        <property type="entry name" value="BUD13 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51363">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="W2" evidence="3">
        <location>
            <begin position="770"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="62"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="431"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="634"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="62"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="435"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="979" mass="117209" checksum="A7003DE17CD4CAEC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY97</accession>
    <name>A0A1J1GY97_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Telomerase reverse transcriptase</fullName>
            <ecNumber evidence="2 13">2.7.7.49</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Telomerase catalytic subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">TERT</name>
        <name evidence="16" type="ORF">PGAL8A_00510500</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.49"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="13">Chromosome</location>
            <location evidence="13">Telomere</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 13">Belongs to the reverse transcriptase family. Telomerase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="2 13"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530333.1">
        <property type="nucleotide sequence ID" value="XM_028673929.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733638"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00510500"/>
    <dbReference type="OMA" id="NTHEEQN"/>
    <dbReference type="OrthoDB" id="289721at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000333">
        <property type="term" value="C:telomerase catalytic core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003720">
        <property type="term" value="F:telomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070034">
        <property type="term" value="F:telomerase RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042162">
        <property type="term" value="F:telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007004">
        <property type="term" value="P:telomere maintenance via telomerase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021891">
        <property type="entry name" value="Telomerase_RBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003545">
        <property type="entry name" value="Telomerase_RT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12066">
        <property type="entry name" value="TELOMERASE REVERSE TRANSCRIPTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12066:SF0">
        <property type="entry name" value="TELOMERASE REVERSE TRANSCRIPTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12009">
        <property type="entry name" value="Telomerase_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00975">
        <property type="entry name" value="Telomerase_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 13" id="KW-0158">Chromosome</keyword>
    <keyword evidence="14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 13 16" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 13 16" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="9 13" id="KW-0779">Telomere</keyword>
    <keyword evidence="5 13 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="15">
        <location>
            <begin position="1226"/>
            <end position="1773"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="453"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU365061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="CRG97532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2164" mass="263289" checksum="A83BC5BD697D017B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYA7</accession>
    <name>A0A1J1GYA7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00511300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530341.1">
        <property type="nucleotide sequence ID" value="XM_028673938.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYA7"/>
    <dbReference type="GeneID" id="39733646"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00511300"/>
    <dbReference type="OrthoDB" id="391935at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="214" mass="25097" checksum="08F22D56391FBB87" modified="2017-02-15" version="1">MAGTLNLNDLKDEPILYYENALSYVFCNSSEENKKEIPTCVIYPSKNIKIGFPICSIKNINKNENLLNDNDIHSNRFNEEPLITYASESKDIYPLRVKVYYTILYILILLQIFVMIFFKDNINFITTGDINLWQNYIFIFTGLSHILVIMSKLSKLKNYLFDMYTSLSLFFFILSVLTINCFSSFLISIIQFFIFYLHLKINFYVMPHSCVVPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYB4</accession>
    <name>A0A1J1GYB4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">MORN repeat protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00502600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530254.1">
        <property type="nucleotide sequence ID" value="XM_028673841.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733559"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00502600"/>
    <dbReference type="OrthoDB" id="377104at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43215">
        <property type="entry name" value="RADIAL SPOKE HEAD 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43215:SF14">
        <property type="entry name" value="RADIAL SPOKE HEAD 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="834"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="880"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1358"/>
            <end position="1379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1385"/>
            <end position="1406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1559"/>
            <end position="1576"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1596"/>
            <end position="1616"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1628"/>
            <end position="1652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="737"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2110"/>
            <end position="2137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3128"/>
            <end position="3151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3432"/>
            <end position="3505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="2113"/>
            <end position="2129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="3432"/>
            <end position="3493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="3495"/>
            <end position="3505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3986" mass="480250" checksum="2FF6E8B27EAD7660" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYF8</accession>
    <name>A0A1J1GYF8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ras-related protein Rab-11A, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00516900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endomembrane system</location>
            <topology evidence="7">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530397.1">
        <property type="nucleotide sequence ID" value="XM_028674001.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYF8"/>
    <dbReference type="GeneID" id="39733702"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00516900"/>
    <dbReference type="OMA" id="DSPDMRK"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01868">
        <property type="entry name" value="Rab11_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000067">
        <property type="entry name" value="ras-related protein RABA1f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0636">Prenylation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="184"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG97596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="216" mass="24726" checksum="AC2452E2E4EE2583" modified="2017-02-15" version="1">MAMKEDYYDYLFKIVLIGDSGVGKSNLLSRFTRDEFNLESKSTIGVEFATKSIQLKNNKIIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDITKKNSFENIEKWLKELRDNADTNIVILLVGNKSDLKHLRVINDNDATQFAKKEKLAFIETSALESTNVELAFHQLLNEIYNVRQKKQATTKEDNLSIQPRGKKINVDDDNDQNDTKKKSKCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYH0</accession>
    <name>A0A1J1GYH0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">26S protease regulatory subunit 7, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00507700</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530305.1">
        <property type="nucleotide sequence ID" value="XM_028673898.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYH0"/>
    <dbReference type="GeneID" id="39733610"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00507700"/>
    <dbReference type="OMA" id="TEAGMYC"/>
    <dbReference type="OrthoDB" id="1664597at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19502">
        <property type="entry name" value="RecA-like_PAN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000005">
        <property type="entry name" value="26S protease regulatory subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000037">
        <property type="entry name" value="26S protease regulatory subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000027">
        <property type="entry name" value="26S protease regulatory subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048723">
        <property type="entry name" value="OB_PRS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21236">
        <property type="entry name" value="OB_PRS7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-0647">Proteasome</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="11">
        <location>
            <begin position="195"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG97504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="420" mass="46823" checksum="99C0DEB23BDE1764" modified="2017-02-15" version="1">MQEETDTQSKPLDDEDINILKSYGSGPYSKSIKKVEGDISGLLTNINKLCGVRESDTGLCLPNQWDLQLDKQMLNEEQPLQVARCTKIINADTDQTKYIINVKQIAKFVVGLGDKVAPTDIEEGMRVGVDRTKYKIQILLPPKIDPTVTMMTVEEKPDITYNDIGGCKEQLEKLREVVEMPLLQPERFVTLGIDPPKGVLLYGPPGTGKTLTARAIANRTDACFICVIGSELVQKYVGEGARMVRELFQMAKSKKACILFIDEVDAIGGSRGDESAHGDHEVQRTMLEIVNQLDGFDNRGNIKVLMATNRPDTLDSALVRPGRIDRKIEFSLPDLEGRTHIFKIHANTMNMSRDVRFELLARLCPNSTGSDIRSVCTEAGMFAIRARRKTITEKDLLLAINKVIHGCKQFSATGKYMVYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYP1</accession>
    <name>A0A1J1GYP1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Apicoplast ribosomal protein L33, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00526000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530485.1">
        <property type="nucleotide sequence ID" value="XM_028674098.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYP1"/>
    <dbReference type="GeneID" id="39733793"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00526000"/>
    <dbReference type="OrthoDB" id="361870at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.120">
        <property type="entry name" value="Ribosomal protein L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00294">
        <property type="entry name" value="Ribosomal_bL33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001705">
        <property type="entry name" value="Ribosomal_bL33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038584">
        <property type="entry name" value="Ribosomal_bL33_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001860">
        <property type="entry name" value="PRK00595.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01023">
        <property type="entry name" value="rpmG_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43168">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L33, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43168:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL33C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00471">
        <property type="entry name" value="Ribosomal_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="107" mass="13051" checksum="0465D667650CB4EB" modified="2017-02-15" version="1">MKKCDLIIYSFFFLLIIKCYNQFIILNNIKMINPIVKNIYKSKRYVNIYAKKKNRKVVVLECTEARKLGKRPSRYVTEKNKINTPKKLQLYKYNKYLKRRTLHVEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYR7</accession>
    <name>A0A1J1GYR7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">G-patch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00337300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528960.1">
        <property type="nucleotide sequence ID" value="XM_028672404.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYR7"/>
    <dbReference type="GeneID" id="39731903"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00337300"/>
    <dbReference type="OMA" id="NQESSIC"/>
    <dbReference type="OrthoDB" id="10019757at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050656">
        <property type="entry name" value="PINX1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23149">
        <property type="entry name" value="G PATCH DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23149:SF9">
        <property type="entry name" value="G PATCH DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G-patch" evidence="2">
        <location>
            <begin position="21"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="258" mass="30430" checksum="38CAE3E7B859359A" modified="2017-02-15" version="1">MSKKYYDKLLSDIQNQSKPVESKFGSYILKKFGWEKGKGLGKHENGEVNIMKIKKYGEHGLGYNEHEEENEKWWENMYNNCAKNIKKINNNKNLFSGREDNLHSSSDNKIQNDKNENIKYSIFIKKDNSTISTNNQESSICNLEKKKNLIVIDNKGTDNKKKIKIKNKEINKKRNYEQIIDKNNTFNKNVLNEIKSEGITNNNGKITIKKKNKKINKEINDTENLNGKKELKIKKKEKKKKKKKRKKEKKKKRLTDEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYU7</accession>
    <name>A0A1J1GYU7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Diphthamide biosynthesis protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00532400</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2 [3Fe-4S](0)-[protein] + 2 Fe(2+)-[Dph3] + NADH = 2 [4Fe-4S](1+)-[protein] + 2 [Dph3] + NAD(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:71239"/>
            <dbReference type="Rhea" id="RHEA-COMP:17997"/>
            <dbReference type="Rhea" id="RHEA-COMP:17998"/>
            <dbReference type="Rhea" id="RHEA-COMP:18001"/>
            <dbReference type="Rhea" id="RHEA-COMP:18002"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:33723"/>
            <dbReference type="ChEBI" id="CHEBI:47402"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83228"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[3Fe-4S](1+)-[protein] + Fe(2+)-[Dph3] = [3Fe-4S](0)-[protein] + Fe(3+)-[Dph3]</text>
            <dbReference type="Rhea" id="RHEA:71235"/>
            <dbReference type="Rhea" id="RHEA-COMP:17996"/>
            <dbReference type="Rhea" id="RHEA-COMP:17997"/>
            <dbReference type="Rhea" id="RHEA-COMP:18002"/>
            <dbReference type="Rhea" id="RHEA-COMP:18003"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:33751"/>
            <dbReference type="ChEBI" id="CHEBI:47402"/>
            <dbReference type="ChEBI" id="CHEBI:83228"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DPH3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530547.1">
        <property type="nucleotide sequence ID" value="XM_028674167.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYU7"/>
    <dbReference type="GeneID" id="39733857"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00532400"/>
    <dbReference type="OMA" id="IYDPDMF"/>
    <dbReference type="OrthoDB" id="66964at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.660.10:FF:000004">
        <property type="entry name" value="Diphthamide biosynthesis protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.660.10">
        <property type="entry name" value="DPH Zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044248">
        <property type="entry name" value="DPH3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007872">
        <property type="entry name" value="DPH_MB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036671">
        <property type="entry name" value="DPH_MB_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21454:SF31">
        <property type="entry name" value="DIPHTHAMIDE BIOSYNTHESIS PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21454">
        <property type="entry name" value="DPH3 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05207">
        <property type="entry name" value="Zn_ribbon_CSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144217">
        <property type="entry name" value="CSL zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51074">
        <property type="entry name" value="DPH_MB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DPH-type MB" evidence="8">
        <location>
            <begin position="17"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00036267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00041070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG97746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="81" mass="9579" checksum="A686422A4451E9F0" modified="2017-02-15" version="1">MIVENNNYEANEAYNVIYEEVKLEDFEFDESIKTFFYPCPCGDIFEITLEDLLKGENILRCPSCSLTIKIIYDFNNLKKYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYV5</accession>
    <name>A0A1J1GYV5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ras-related protein Rab-5B, putative</fullName>
            <ecNumber evidence="2">3.6.5.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">RAB5b</name>
        <name evidence="2" type="ORF">PGAL8A_00506800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.2" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530296.1">
        <property type="nucleotide sequence ID" value="XM_028673889.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYV5"/>
    <dbReference type="GeneID" id="39733601"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00506800"/>
    <dbReference type="OMA" id="PKNEPQC"/>
    <dbReference type="OrthoDB" id="63533at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003925">
        <property type="term" value="F:G protein activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00154">
        <property type="entry name" value="Rab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001457">
        <property type="entry name" value="Ras-related protein Rab-5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47978">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="206" mass="23299" checksum="723EA2326840BB48" modified="2017-02-15" version="1">MGCSSSSQRYNSQKNINILTKPLEEKNKCVKDTKVKIVLLGDSGVGKSSIALYLCHGRFSEKHQVTIGAAFLHHTVELKNGANMKLHIWDTGGQERFRSMAPLYYRDAYGAIVVYDSNNVESFDSLKYWINEIKSKGARNCCIVVAANKKDLPKKINSEMVMKFCEEENVSFIECSAKTGENINSLFEKIASRIYIAFKEVLFYNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ28</accession>
    <name>A0A1J1GZ28_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00414100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529365.1">
        <property type="nucleotide sequence ID" value="XM_028672853.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ28"/>
    <dbReference type="GeneID" id="39732671"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00414100"/>
    <dbReference type="OMA" id="RYIPTQE"/>
    <dbReference type="OrthoDB" id="378653at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="82" mass="9965" checksum="4035AEB8F50DB7E8" modified="2017-02-15" version="1">MNKNKHRSKKRLPKGRERYVPTQEEVERRNAEISRRQYEEESEEDSENEKENQENKKETSENEKMIDNKSNIKDNEKSPLNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ46</accession>
    <name>A0A1J1GZ46_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00350900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529096.1">
        <property type="nucleotide sequence ID" value="XM_028672556.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ46"/>
    <dbReference type="GeneID" id="39732039"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00350900"/>
    <dbReference type="OrthoDB" id="343702at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="271"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="727"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="527"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="271"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="342"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="733"/>
            <end position="750"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="837" mass="99672" checksum="E9C0A696FA406F98" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ84</accession>
    <name>A0A1J1GZ84_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Histone-lysine N-methyltransferase, H3 lysine-4 specific, putative</fullName>
            <ecNumber evidence="9">2.1.1.43</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SET10</name>
        <name evidence="9" type="ORF">PGAL8A_00535100</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.43" evidence="9"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530574.1">
        <property type="nucleotide sequence ID" value="XM_028674196.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733884"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00535100"/>
    <dbReference type="OMA" id="FIHAPFF"/>
    <dbReference type="OrthoDB" id="332390at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15489">
        <property type="entry name" value="PHD_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="8">
        <location>
            <begin position="1002"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="321"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1244"/>
            <end position="1307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1507"/>
            <end position="1555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1600"/>
            <end position="1620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1770"/>
            <end position="1794"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1134"/>
            <end position="1168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1244"/>
            <end position="1262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1272"/>
            <end position="1300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1507"/>
            <end position="1521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1535"/>
            <end position="1548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1600"/>
            <end position="1613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1770"/>
            <end position="1780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1785"/>
            <end position="1794"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG97773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1826" mass="216051" checksum="E63456CFF4A0C27D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZE6</accession>
    <name>A0A1J1GZE6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00425300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529477.1">
        <property type="nucleotide sequence ID" value="XM_028672979.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZE6"/>
    <dbReference type="GeneID" id="39732785"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00425300"/>
    <dbReference type="OMA" id="INEDNHM"/>
    <dbReference type="OrthoDB" id="381930at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1102" mass="135316" checksum="A4EE8BCB1F8B0691" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZF4</accession>
    <name>A0A1J1GZF4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein phosphatase PPM8, putative</fullName>
            <ecNumber evidence="2">3.1.3.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PPM8</name>
        <name evidence="2" type="ORF">PGAL8A_00362700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529208.1">
        <property type="nucleotide sequence ID" value="XM_028672680.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZF4"/>
    <dbReference type="GeneID" id="39732157"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00362700"/>
    <dbReference type="OMA" id="NIHNANQ"/>
    <dbReference type="OrthoDB" id="420076at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF792">
        <property type="entry name" value="GM14286P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="1">
        <location>
            <begin position="235"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="570" mass="66685" checksum="1D02366FF3B677F2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZH1</accession>
    <name>A0A1J1GZH1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00030600</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530670.1">
        <property type="nucleotide sequence ID" value="XM_028674303.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZH1"/>
    <dbReference type="GeneID" id="39728829"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00030600"/>
    <dbReference type="OMA" id="FKCCKYL"/>
    <dbReference type="OrthoDB" id="343092at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048476">
        <property type="term" value="C:Holliday junction resolvase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction DNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031573">
        <property type="term" value="P:mitotic intra-S DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.670">
        <property type="entry name" value="Crossover junction endonuclease EME1, DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042530">
        <property type="entry name" value="EME1/EME2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033310">
        <property type="entry name" value="Mms4/EME1/EME2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21077:SF5">
        <property type="entry name" value="CROSSOVER JUNCTION ENDONUCLEASE MMS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21077">
        <property type="entry name" value="EME1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21292">
        <property type="entry name" value="EME1-MUS81_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0469">Meiosis</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG97871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="330" mass="39380" checksum="500F56C5E2E150F5" modified="2017-02-15" version="1">MDEIKIIFSNDLKLSTHYEILKSFLKNEEENDKNDTNYSNMLNYDSKEIQEPSIHFDSVCFIYTNFSYKSHFTLINEKKSEKISLHEESDTSYYEDTKIDEKYVLSLILIIIEENYLEYQYDKEKNIFHKVEKLQKEYKNVRIMCIFIGIREILDRTNIKENYKFENINKNENIIINNKDFDSFIAALLVRYHIDSVELDNITHLNKYIFKCCKYLYQSKIRKPNSYFKVKPLSLNQLTNSNTNENKNYSTWISQLMQISGISEDISKKIAEVFKTPFDLIRHFKKINDEECLKDIIINSSYGERKLGKALSKKIYRVFSPYSKSDNFVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZK4</accession>
    <name>A0A1J1GZK4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00047300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Endosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Lysosome membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530835.1">
        <property type="nucleotide sequence ID" value="XM_028674487.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728998"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00047300"/>
    <dbReference type="OMA" id="MCIYMEK"/>
    <dbReference type="OrthoDB" id="378493at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45981">
        <property type="entry name" value="LD02310P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="793"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="831"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="664"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1359"/>
            <end position="1477"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1570"/>
            <end position="1611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="686"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1359"/>
            <end position="1368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1382"/>
            <end position="1424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1425"/>
            <end position="1438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1439"/>
            <end position="1462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1463"/>
            <end position="1477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG98038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1703" mass="206652" checksum="504929A39EB70372" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZL9</accession>
    <name>A0A1J1GZL9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00032700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530689.1">
        <property type="nucleotide sequence ID" value="XM_028674325.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZL9"/>
    <dbReference type="GeneID" id="39728850"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00032700"/>
    <dbReference type="OMA" id="EFCKYCE"/>
    <dbReference type="OrthoDB" id="387446at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="384"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="450" mass="52624" checksum="D1A1921A9F9EC89B" modified="2017-02-15" version="1">MNYNIYLGKFCVKPKIIKQEILKDWRDCLNSLNNYEDYHIATYDRNNICSVIDSTFSNWNEIINDEDKFCLLKDSNMMILIKNVSNSKCTSTCLHEKKFSKWSSCNDLGKESYKIRVKGILSKPYGLDDCFGTLQKKNCFNKEIVTGDFLNDTASCSFNFSMHIDKCSQICNGNIDINLSLFRILHKNVDNYGLSCPTNENIILVEFCKYCEKKKEKKRDNNNNNKVSLADLKRHEDFSINSSENYKKRSIQKFSPQYTLSSSLDSGLNINKNKFSFVSLYSKNNTSDTIPMNFLIHNSVMNITDNEYDKLMKEGSVKIYKDNHIVDYKYEDFEIKDENEINENKEKDNNKDNIYEQIDDNNTSEKQSEDNYKNHKKYIKDDDIIKYAIIISIFLILLLIIFIIYYFNLIRKIKGILFKKKRKPNKSMTIAAEKSTGIYIDDSFAETTNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZN8</accession>
    <name>A0A1J1GZN8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">AP-2 complex subunit mu, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">AP2-MU</name>
        <name evidence="6" type="ORF">PGAL8A_00532900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530552.1">
        <property type="nucleotide sequence ID" value="XM_028674172.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZN8"/>
    <dbReference type="GeneID" id="39733862"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00532900"/>
    <dbReference type="OMA" id="MPICELS"/>
    <dbReference type="OrthoDB" id="10259133at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030131">
        <property type="term" value="C:clathrin adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000002">
        <property type="entry name" value="AP-2 complex subunit mu, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1170">
        <property type="entry name" value="Mu homology domain, subdomain B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050431">
        <property type="entry name" value="Adaptor_comp_med_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001392">
        <property type="entry name" value="Clathrin_mu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10529">
        <property type="entry name" value="AP COMPLEX SUBUNIT MU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00928">
        <property type="entry name" value="Adap_comp_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00314">
        <property type="entry name" value="CLATHRINADPT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MHD" evidence="5">
        <location>
            <begin position="252"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="584" mass="68920" checksum="1572A09709773FB5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZY7</accession>
    <name>A0A1J1GZY7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00048400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530846.1">
        <property type="nucleotide sequence ID" value="XM_028674500.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZY7"/>
    <dbReference type="GeneID" id="39729009"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00048400"/>
    <dbReference type="OMA" id="VFWLWLQ"/>
    <dbReference type="OrthoDB" id="378019at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="855" mass="104182" checksum="46366CC954C0D7D9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H035</accession>
    <name>A0A1J1H035_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">UBX domain, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00447900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529701.1">
        <property type="nucleotide sequence ID" value="XM_028673227.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H035"/>
    <dbReference type="GeneID" id="39733012"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00447900"/>
    <dbReference type="OMA" id="YFCESIF"/>
    <dbReference type="OrthoDB" id="1026733at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01767">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049483">
        <property type="entry name" value="FAF1_2-like_UAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006577">
        <property type="entry name" value="UAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050730">
        <property type="entry name" value="UBX_domain-protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23322:SF1">
        <property type="entry name" value="FAS-ASSOCIATED FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23322">
        <property type="entry name" value="FAS-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21021">
        <property type="entry name" value="FAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00594">
        <property type="entry name" value="UAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00166">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBX" evidence="3">
        <location>
            <begin position="286"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="238"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="376" mass="44752" checksum="8EE277DF6F5347DF" modified="2017-02-15" version="1" fragment="single">EFNSTTENLENIDKINEIKESEEGIFKKDENEIEKKNFLYIFNPLGKIIFPIFKNIYYAISTFFKLLTTFILTPYDENNFTSYYEHKYGKMHTNFFKGNLNEAILKSRKEEKLLLVYLHIDNNESSYFCENIFNNSEIKSFFDENCILYAQDISKGDTKELNNILNVFILPQISIILTCYVKDIKELTIVYGNPSVNHIINSITHCIEQMQVKKENCESLKYKTYNDRLIREEQDREYQEALKKDKLIEEQKKKKENEKLKKTQYKKEIKKKREENCKKFPLSIKENEQVTEISIRLSNGTRIQNKFSVNHTIEDIYEWAECCEFLEENIKIPYKFELICGHSKSILQKVKNKIKEFDLYPNAVLNLKSLDTSDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0D4</accession>
    <name>A0A1J1H0D4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CHCH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00456600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529789.1">
        <property type="nucleotide sequence ID" value="XM_028673326.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0D4"/>
    <dbReference type="GeneID" id="39733099"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00456600"/>
    <dbReference type="OMA" id="CQFYLDQ"/>
    <dbReference type="OrthoDB" id="1106148at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055304">
        <property type="entry name" value="CHCHD2/10-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13523:SF2">
        <property type="entry name" value="COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13523">
        <property type="entry name" value="COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2/NUR77"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="148" mass="16190" checksum="991751B5C6EF9D21" modified="2017-02-15" version="1">MGRSSRSRSNSLSTRSSFVKRSGSNDMNRRNNTSAQNYSGNLMQQQNSGKSGFLSNMMGTVASGMASGVGFGVAQRAVDSILGPRHVEVSHTNNNSQMNQSAAISSERNNLYKCQPYMDELNQCLMRHSDVSLCQNYADSLKSCQQSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0E2</accession>
    <name>A0A1J1H0E2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Secreted ookinete protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PSOP12</name>
        <name evidence="3" type="ORF">PGAL8A_00035100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530714.1">
        <property type="nucleotide sequence ID" value="XM_028674352.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0E2"/>
    <dbReference type="GeneID" id="39728875"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00035100"/>
    <dbReference type="OrthoDB" id="380483at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041396">
        <property type="entry name" value="CyRPA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18638">
        <property type="entry name" value="CyRPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013176095" evidence="1">
        <location>
            <begin position="24"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="Cysteine-rich protective antigen 6 bladed" evidence="2">
        <location>
            <begin position="41"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="348" mass="40914" checksum="73165AAEAEC21BE1" modified="2017-02-15" version="1">MITLKKIFYFFYLTYIIVKKVEGLDNSVVNYDNYTLYQFGNCMKQQYIYFLESIYKLCYLWKTIDEKTVSKILVQKGKDSSWEVKSELIYRNKDLSSLYFSYVLNKELIVLMCYSNFQLRKYECVRSVSHNGIKFNTTDTSFSSDPHSDSSMDNYSSLPFNFSGVNYLLICSLNKNPSRDGSLKLFITCSGSKDKGITWKTIFRFYYSSDSSFKYYKLAPRISEGSIGFQYVKHNNSTWTHEYIECNHRKDYDFECKNIDLQKKNKVLQIALKVGNYYVSSYMGKNNYLCYLYYTSDNIVLIKTKINKNKKGDCNPRDLIMVDDSKVVLVYADGMNIDGFSTYRFINN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0J1</accession>
    <name>A0A1J1H0J1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cyclin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CYC3</name>
        <name evidence="3" type="ORF">PGAL8A_00040000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the cyclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530762.1">
        <property type="nucleotide sequence ID" value="XM_028674405.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0J1"/>
    <dbReference type="GeneID" id="39728924"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00040000"/>
    <dbReference type="OMA" id="QISIYKY"/>
    <dbReference type="OrthoDB" id="337735at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd20558">
        <property type="entry name" value="CYCLIN_ScPCL7-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012389">
        <property type="entry name" value="Cyclin_P/U"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF108">
        <property type="entry name" value="PROTEIN CNPPD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF027110">
        <property type="entry name" value="PREG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0195">Cyclin</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR027110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="223" mass="26322" checksum="2BB1496E81876489" modified="2017-02-15" version="1">MDYDIEADVPRTDKNYILYIPIVLDQIVKMNKKEGKITSFHASKIPEISIKNYVERIGKYIGCSNECFVLLMIYVDRIIKLHKDITLSLLCIHRIIITAAMIAAKFFDDLYYSNSFYAKVGGVTTKELNKLEACFLNLLDYKLYVSSEEYDFYRKYISLAVQKFLNNKKITRIPIAKPYNLFNYTSPDKSNMFLEREQNVHSDMRKFSRISQNKKKNYQYDNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0S0</accession>
    <name>A0A1J1H0S0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DDB1- and CUL4-associated factor 13</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">WD repeat and SOF domain-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00059800</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat DCAF13/WDSOF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530960.1">
        <property type="nucleotide sequence ID" value="XM_028674626.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0S0"/>
    <dbReference type="GeneID" id="39729123"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00059800"/>
    <dbReference type="OMA" id="NCIRICT"/>
    <dbReference type="OrthoDB" id="10249065at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007287">
        <property type="entry name" value="Sof1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051733">
        <property type="entry name" value="WD_repeat_DCAF13/WDSOF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22851:SF0">
        <property type="entry name" value="DDB1- AND CUL4-ASSOCIATED FACTOR 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22851">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA U3 SNORNA ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04158">
        <property type="entry name" value="Sof1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 9" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="62"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="105"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Sof1-like protein" evidence="11">
        <location>
            <begin position="376"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="436"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="436"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="446"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG98163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="464" mass="54319" checksum="E9998D9B4F202894" modified="2017-02-15" version="1">MEIKILHRNPDDYKSSTSTSNYKHIRSFDKNIHLFQREIEYKRALNATKIDKIFAKPLVKCLDDHDDSIRSICVSNKNLTDLYSGSCNGFINVWNILDKKLMRKIKAHDGFVRGLCVSYDEKYLFSCGDDKYIKQWVVDKNKNINELNEDDVVQQDFSNFKYLENEVVPKKIYVCKSVPNSIDKHFSDPLIISGSQTLDVWDYYRNNAISSFDYNSEYIYYVKFNYAQRNLVGLTLSDNSVGLVDIRSKSPIKKLFLKYRSNSLSWNNMNPKHFIVANEDSNLYTFDMRYLKTAYLVHKGFVNAVLDVDFSPIGNKFVACSYDKTIRLFNSDESKSYDVYHTKRMQHVLCCKFSLDAKYIFSGSSDMCLRIWKSCSHEPSGVLSNKEKQAINYRNKLKEKYASLKEIKRIREHHHVPALIKSLSDKKKIMLEAKKRKEKNKIKHSKNPDELPIPEKKKIFVTEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0Z5</accession>
    <name>A0A1J1H0Z5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00478900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530013.1">
        <property type="nucleotide sequence ID" value="XM_028673574.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0Z5"/>
    <dbReference type="GeneID" id="39733322"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00478900"/>
    <dbReference type="OMA" id="FFINEYD"/>
    <dbReference type="OrthoDB" id="387553at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="679" mass="80695" checksum="2C7FE64104386DDE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1W9</accession>
    <name>A0A1J1H1W9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00510400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530332.1">
        <property type="nucleotide sequence ID" value="XM_028673928.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1W9"/>
    <dbReference type="GeneID" id="39733637"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00510400"/>
    <dbReference type="OrthoDB" id="375413at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="704" mass="84149" checksum="8D50E7FC73D663AE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H481</accession>
    <name>A0A1J1H481_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zinc finger Ran-binding domain-containing protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PGAL8A_00058900</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the ZRANB2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530951.1">
        <property type="nucleotide sequence ID" value="XM_028674616.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H481"/>
    <dbReference type="GeneID" id="39729114"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00058900"/>
    <dbReference type="OMA" id="GHYDIQG"/>
    <dbReference type="OrthoDB" id="430695at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.10">
        <property type="entry name" value="Zinc finger, RanBP2-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017337">
        <property type="entry name" value="ZRANB2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12999:SF17">
        <property type="entry name" value="ZINC FINGER RAN-BINDING DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12999">
        <property type="entry name" value="ZINC FINGER RAN-BINDING DOMAIN-CONTAINING PROTEIN 2 ZRANB2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00641">
        <property type="entry name" value="Zn_ribbon_RanBP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037956">
        <property type="entry name" value="UCP037956_ZnF_Ran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RanBP2-type" evidence="13">
        <location>
            <begin position="11"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="13">
        <location>
            <begin position="53"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="116"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="133"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="144"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="194"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG98154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="266" mass="32601" checksum="5ED169F7DDB8A9DC" modified="2017-02-15" version="1">MESHKYTDKLKSGDWICTDENCRNLNFSKRTHCNRCSKPRPKIKKNFKQIFFKSNDWKCDDCGNINWAKREKCNICSKSRYSKKLNEFRSNKEIRTGKGGGHYDIQWNNEKRVHDSEDEEYDEFGRKKKKKKKIDDEEEKSRGNNENNDINNNKNNNNNKDMLYKNNISKNKNYENSRSRSISSNTYKKVKKNNIYDEVKEHKKSNGDHRKYDRRYDYDKKYNDKKIDHDQKYNFDNRGNDYDKKYDDRKYNYDKKYDDRKKHRRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2012-05-16" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>H7CDW7</accession>
    <name>H7CDW7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Apicoplast ribosomal protein S4, putative</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Small subunit ribosomal protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rps4</name>
        <name evidence="4" type="synonym">RPS4</name>
        <name evidence="4" type="ORF">PGAL8A_API00200</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <geneLocation type="apicoplast" evidence="3"/>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Mol. Biol. Evol." volume="29" first="2095" last="2099">
            <title>The Plasmodium Apicoplast Genome: Conserved Structure and Close Relationship of P. ovale to Rodent Malaria Parasites.</title>
            <authorList>
                <person name="Arisue N."/>
                <person name="Hashimoto T."/>
                <person name="Mitsui H."/>
                <person name="Palacpac N.M.Q."/>
                <person name="Kaneko A."/>
                <person name="Kawai S."/>
                <person name="Hasegawa M."/>
                <person name="Tanabe K."/>
                <person name="Horii T."/>
            </authorList>
            <dbReference type="PubMed" id="22396524"/>
            <dbReference type="DOI" id="10.1093/molbev/mss082"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">A8</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">8A</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AB649424">
        <property type="protein sequence ID" value="BAL70737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LN835293">
        <property type="protein sequence ID" value="CRG98226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009325453.1">
        <property type="nucleotide sequence ID" value="NC_031963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="H7CDW7"/>
    <dbReference type="GeneID" id="30315760"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_API00200"/>
    <dbReference type="OMA" id="YICYNYC"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Apicoplast API"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1050.10">
        <property type="entry name" value="Ribosomal Protein S4 Delta 41, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="entry name" value="RNA-binding S4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55174">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0933">Apicoplast</keyword>
    <keyword evidence="3" id="KW-0934">Plastid</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RNA-binding S4" evidence="2">
        <location>
            <begin position="89"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAL70737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG98226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="208" mass="26091" checksum="020BFFAE97572A3A" modified="2012-05-16" version="1">MIKFLISKIKVLKKLNIPFLLYFSSKYNYKLYNNKILYNKTYYNLKLKFIRYICYNYCITYKQYLYYINKIRKNYKYVIYFKLLNILESRLDVFLVNIGCFKTILQSRYYIKSQNIYINNINIKYYNINIKNNDIIFFNSKIKYIILKNLIYKYNIYLYIFKLYKYNFIKIYSYNENFILCIYNLKIKIVNNILLNNILYIYNNFFYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2012-07-11" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>I2FKC3</accession>
    <name>I2FKC3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Enolase</fullName>
            <ecNumber evidence="8">4.2.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="31" type="primary">ENO</name>
        <name evidence="32" type="ORF">PGAL8A_00392100</name>
    </gene>
    <organism evidence="31">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="31" key="1">
        <citation type="journal article" date="2012" name="Gene" volume="502" first="36" last="39">
            <title>Age of the last common ancestor of extant Plasmodium parasite lineages.</title>
            <authorList>
                <person name="Hayakawa T."/>
                <person name="Tachibana S."/>
                <person name="Hikosaka K."/>
                <person name="Arisue N."/>
                <person name="Matsui A."/>
                <person name="Horii T."/>
                <person name="Tanabe K."/>
            </authorList>
            <dbReference type="PubMed" id="22555021"/>
            <dbReference type="DOI" id="10.1016/j.gene.2012.04.037"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="32 33" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="32 33">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="23">Glycolytic enzyme that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate. In addition to glycolysis, involved in various processes such as parasite development and invasion. Plays an essential role during ookinete invasion of the mosquito vector midgut by mediating the interaction of the ookinete with the midgut epithelium and, further, by binding to mammalian host plasminogen in the blood meal, whose conversion to active plasmin promotes the invasion process.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="25">
            <text>(2R)-2-phosphoglycerate = phosphoenolpyruvate + H2O</text>
            <dbReference type="Rhea" id="RHEA:10164"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.2.1.11"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="25">
            <dbReference type="Rhea" id="RHEA:10165"/>
        </physiologicalReaction>
        <physiologicalReaction direction="right-to-left" evidence="25">
            <dbReference type="Rhea" id="RHEA:10166"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="28">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="28">Mg(2+) is required for catalysis and for stabilizing the dimer.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="24">Homodimer. Forms a complex at least composed of DegP, ENO and HSP70. Interacts with G-actin. Interacts (via the DKSLVK motif) with mammalian host PLG/plasminogen (present in the mosquito blood meal); the interaction occurs at the ookinete cell surface and is required for ookinete invasion of the mosquito midgut. Interacts with A.gambiae EBP; depending on the Plasmodium species, the interaction is either involved in ookinete invasion of the mosquito midgut (P.berghei) or is dispensable (P.falciparum).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Cell surface</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
            <location evidence="4">Cytoskeleton</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Vacuole</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the enolase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.11" evidence="8"/>
    <dbReference type="EMBL" id="AB571132">
        <property type="protein sequence ID" value="BAM15608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527038.1">
        <property type="nucleotide sequence ID" value="XM_028670269.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="I2FKC3"/>
    <dbReference type="GeneID" id="39732451"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00392100"/>
    <dbReference type="OMA" id="GMSITKI"/>
    <dbReference type="OrthoDB" id="1739814at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00187"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000015">
        <property type="term" value="C:phosphopyruvate hydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004634">
        <property type="term" value="F:phosphopyruvate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03313">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.10:FF:000001">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.120:FF:000002">
        <property type="entry name" value="Enolase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="entry name" value="Enolase-like C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="entry name" value="Enolase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00318">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000941">
        <property type="entry name" value="Enolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020810">
        <property type="entry name" value="Enolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020809">
        <property type="entry name" value="Enolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020811">
        <property type="entry name" value="Enolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01060">
        <property type="entry name" value="eno"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902:SF1">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00113">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03952">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001400">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00148">
        <property type="entry name" value="ENOLASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00002">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00178">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00001">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01192">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01193">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="Enolase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="Enolase N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00164">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="17" id="KW-0007">Acetylation</keyword>
    <keyword evidence="10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="20" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="19" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="12" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="21 32" id="KW-0456">Lyase</keyword>
    <keyword evidence="15 28" id="KW-0460">Magnesium</keyword>
    <keyword evidence="18" id="KW-0472">Membrane</keyword>
    <keyword evidence="28" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="22" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="33" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="16" id="KW-0832">Ubl conjugation</keyword>
    <keyword evidence="14" id="KW-0926">Vacuole</keyword>
    <feature type="domain" description="Enolase N-terminal" evidence="30">
        <location>
            <begin position="5"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Enolase C-terminal TIM barrel" evidence="29">
        <location>
            <begin position="150"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="26">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="26">
        <location>
            <position position="356"/>
        </location>
    </feature>
    <feature type="binding site" evidence="27">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="27">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="28">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="28">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="27">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="28">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="27">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="27">
        <location>
            <begin position="383"/>
            <end position="386"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="27">
        <location>
            <position position="407"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00005031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00009604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00012058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00017068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00046218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00046930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="ARBA" id="ARBA00049098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="27">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="28">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="29">
        <source>
            <dbReference type="SMART" id="SM01192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="30">
        <source>
            <dbReference type="SMART" id="SM01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="31">
        <source>
            <dbReference type="EMBL" id="BAM15608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="32">
        <source>
            <dbReference type="EMBL" id="CRG94217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="33">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="446" mass="48904" checksum="5BA3F98FDBC2E0F4" modified="2012-07-11" version="1">MAHLITRISAREILDSRGNPTVEVDLETDIGIFRAAVPSGASTGIYEALELRDNDKTRYLGKGVQEAIKNITNVIAPKLIGLDCREQKKIDRLMVEAIDGTKNEWGWSKSKLGANAILAVSMAVCRAGAAANKISLYKYIANLAEKKDDKMVLPVPCLNVINGGSHAGNKLAFQEFMIVPVGAPTFKEALRYGAEVYHTLKSGIKKKYGIDATNVGDEGGFAPNILNAVEALDLLVDAIKTAGYEGKVKIAMDVAASEFYDENTKLYDLDFKTPNNDKSLVKTGEQLVELYTHLVKKYPIISIEDPFDQDDWENYAKLTKAIGKTVQIVGDDLLVTNPARINKALEKKACNALLLKVNQIGSITEAIEACLLSQKNNWGVMVSHRSGETEDVFIADLVVALRTGQIKTGAPCRSERNAKYNQLLRIEESLGNNAIYAGENFRHQLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL30</accession>
    <name>A0A1J1GL30_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Inner membrane complex protein 1g, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">IMC1g</name>
        <name evidence="1" type="ORF">PGAL8A_00073100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525849.1">
        <property type="nucleotide sequence ID" value="XM_028674923.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL30"/>
    <dbReference type="GeneID" id="39729256"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00073100"/>
    <dbReference type="OrthoDB" id="371494at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022086">
        <property type="entry name" value="IMCp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12314">
        <property type="entry name" value="IMCp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="300" mass="35002" checksum="36A0D786A38B05B7" modified="2017-02-15" version="1">MCSTNKGFKCCSAENVFEPAGNENQAYPQVVNKQLPPKVLEPIVQNKIVEVPKEVYLEKIIEVPQIKTVERIVEQIKPIIKYKNVYRPKTVYVEKIKNVDRIIYQEKIIEVPQIRTVEKVVDVPVYVDRERIIKVPKYMVVERVIPILKTTKTERVMEVPEVNCPDIDVNEKVETKERIEVKDLKENQTTKVVDEKEVQLLNELNNSNMNLEPTINIETTQEQTMKNGTQENFCTTLGCKFLPIYQNFVKVASPILRIHQERERQMINSNVYRAKQIGFPRIRIARTPHTNQRSCYCNCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL32</accession>
    <name>A0A1J1GL32_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Exosome complex component CSL4, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CSL4</name>
        <name evidence="6" type="ORF">PGAL8A_00083200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525950.1">
        <property type="nucleotide sequence ID" value="XM_028670799.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL32"/>
    <dbReference type="GeneID" id="39729356"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00083200"/>
    <dbReference type="OMA" id="PMVPVGW"/>
    <dbReference type="OrthoDB" id="440760at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039771">
        <property type="entry name" value="Csl4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019495">
        <property type="entry name" value="EXOSC1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025721">
        <property type="entry name" value="Exosome_cplx_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF034126">
        <property type="entry name" value="PRK09521.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12686">
        <property type="entry name" value="3'-5' EXORIBONUCLEASE CSL4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12686:SF8">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT CSL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14382">
        <property type="entry name" value="ECR1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10447">
        <property type="entry name" value="EXOSC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110324">
        <property type="entry name" value="Ribosomal L27 protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0271">Exosome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exosome complex component N-terminal" evidence="5">
        <location>
            <begin position="4"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="Exosome complex component CSL4 C-terminal" evidence="4">
        <location>
            <begin position="90"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="188" mass="20988" checksum="082FE135F3BFEDC2" modified="2017-02-15" version="1">MDDIVLPGEVVGCAKDYINGENTYILKDEIRSTILGRKHIIDNENKQIINVDNIKSFVALPKTGDIVICKVYRVTFNIIYCNIILSNGNPLKNSFKGYINKSDIHIYEGELGDNFDCFKQGDIIKAKILSIGQHSSYKLSTVGSDLGVIIALSDKGEILKPVAWNLMVNLSDMSFEQRKVSNDFSIPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLE4</accession>
    <name>A0A1J1GLE4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Nuclear cap-binding protein subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">20 kDa nuclear cap-binding protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00088900</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the RRM NCBP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526007.1">
        <property type="nucleotide sequence ID" value="XM_028671433.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLE4"/>
    <dbReference type="GeneID" id="39729413"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00088900"/>
    <dbReference type="OMA" id="PNVQHMM"/>
    <dbReference type="OrthoDB" id="201398at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005846">
        <property type="term" value="C:nuclear cap binding complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000339">
        <property type="term" value="F:RNA cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12240">
        <property type="entry name" value="RRM_NCBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000541">
        <property type="entry name" value="Nuclear cap-binding protein subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027157">
        <property type="entry name" value="NCBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034148">
        <property type="entry name" value="NCBP2_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18847">
        <property type="entry name" value="20 KD NUCLEAR CAP BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18847:SF0">
        <property type="entry name" value="NUCLEAR CAP-BINDING PROTEIN SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5 8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="9">
        <location>
            <begin position="34"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG93185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="228" mass="27331" checksum="2D1A347FA3EEA8BF" modified="2017-02-15" version="1">MAHLYEEVNKKRKYYDRSLCNDYDDWLKKIQFSKTVYIGNLSIYTTEQQIYEHMSKSGDIEDIIMGLHRKEKSPCGFCFVIYKKREGYIRAVNFLNNSILDGRIIRVDEDLGIIGRRKYGRGKTGVQKRDERNKFYDEDRPAVLDNLASYNTTKKRKFNNFNTYYDRNVKQRRSTNYTLYPNDQKNNKFVNLKPAVTLYPNVQHLMSYRNKNDKLSNFQFKKDSKRNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLI8</accession>
    <name>A0A1J1GLI8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00093700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526055.1">
        <property type="nucleotide sequence ID" value="XM_028671965.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729461"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00093700"/>
    <dbReference type="OMA" id="DMHITHM"/>
    <dbReference type="OrthoDB" id="1716816at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF19">
        <property type="entry name" value="BINDING MONOOXYGENASE, PUTATIVE (JCVI)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="33"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="1013"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="275"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="817"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="902"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="275"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="304"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="909"/>
            <end position="918"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1372" mass="159886" checksum="802BD2FD02CB314F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLY2</accession>
    <name>A0A1J1GLY2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Adenylate kinase 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00109800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the adenylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526215.1">
        <property type="nucleotide sequence ID" value="XM_028673743.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLY2"/>
    <dbReference type="GeneID" id="39729624"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00109800"/>
    <dbReference type="OrthoDB" id="439792at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019205">
        <property type="term" value="F:nucleobase-containing compound kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="321" mass="36964" checksum="3775C84DCAB98F29" modified="2017-02-15" version="1">MGSCQSTSKNNVAEKKEDIKEYVDVSKKNEDVDKVITEVNKEEICKNNDEEKNEIKEEKEVDGEKKKIIIFNGAPGSGKDTQCRLIKQKYNFKILTSSELLKKYLEENKGKLTEDSDTNENKLSEQEKGDLEVVEKCINDGSLVPDEIVSRIFFQNLNYDINNVEFDGILINGFPRTYEQALSFKNNNIKVNALINMTTSKECLLDRINNRLVDPVTNINYDEKIIELIKKKRGGELTEEEEKIVSQNEDYNNLSDEDISRLIKRGDDEENVFHKRFSLYKDNEEKIISLFTDVCKNVDGEKSINEVFDEISSIIDNIVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMJ8</accession>
    <name>A0A1J1GMJ8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Zn2+ or Fe2+ permease, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00137700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526494.1">
        <property type="nucleotide sequence ID" value="XM_028674910.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMJ8"/>
    <dbReference type="GeneID" id="39729902"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00137700"/>
    <dbReference type="OMA" id="QECGIIG"/>
    <dbReference type="OrthoDB" id="448280at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040">
        <property type="entry name" value="ZINC/IRON TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040:SF140">
        <property type="entry name" value="ZRT (ZRT), IRT- (IRT-) LIKE PROTEIN TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="211"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="247"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="307"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="335" mass="38200" checksum="D5E142036E1DF27B" modified="2017-02-15" version="1">MDTFLAKTICIFIFIIVTTTGCLIPYLIGIYGKKHESQNENKIKNILSNLNCFGSGFIFSIIMFHLLPETIFVAIEHDNMKIFNSYDKEIKILYIFFFVFIGFCMQLALEYVLPTDRHICCVLHENENVIPNENYINKLVKTNNNSHNLEMHNVIINEAQYLHACENHNITKKNSWEFLQVLTMQSFFLTLSLAIHSFIEGMVVGTSDQVNYVFINSFCILSHKWIAGITVSISLNQNNLSNSLKIILLMIFIISSPLGIILGYVVQAAGEKITCIINAISIGTLLFIGCEILLNEINEKFSRKVRFTKWISFCCSCIIAFSIICLMAHISPHTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMS3</accession>
    <name>A0A1J1GMS3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">T-complex protein 1 subunit zeta, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CCT6</name>
        <name evidence="8" type="ORF">PGAL8A_00137300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526490.1">
        <property type="nucleotide sequence ID" value="XM_028674906.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMS3"/>
    <dbReference type="GeneID" id="39729898"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00137300"/>
    <dbReference type="OMA" id="LHPRIMT"/>
    <dbReference type="OrthoDB" id="10052040at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03342">
        <property type="entry name" value="TCP1_zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.260.10:FF:000017">
        <property type="entry name" value="T-complex protein 1 subunit zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000004">
        <property type="entry name" value="T-complex protein 1 subunit zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012722">
        <property type="entry name" value="Chap_CCT_zeta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02347">
        <property type="entry name" value="chap_CCT_zeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="543" mass="61597" checksum="7BC38A16914C018A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMY6</accession>
    <name>A0A1J1GMY6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00152600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526638.1">
        <property type="nucleotide sequence ID" value="XM_028675070.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMY6"/>
    <dbReference type="GeneID" id="39730050"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00152600"/>
    <dbReference type="OMA" id="NNSIYPQ"/>
    <dbReference type="OrthoDB" id="427543at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="269" mass="32361" checksum="222A7E7475A094FE" modified="2017-02-15" version="1">MPRGGHKGGLFPVSGIKWGMNERIKKRGLYHNRREDILTPRWGYRYENQNKKYIPDGSSKSFDIDSSKAWPNEKTQWNYFYSINENRYIWPSICAYNPYIKNYILNVLENSENHFSGIGLDEVSNEKNFKKKDYISSNNKNNYLYKLANEFNNSIYPQIEVNLNNNLKRGRIQKLYDIVREENIWKTTQKIKTIESKNVFPYVDDNSTLIRELPLSEILYTKSNLRLKVRRHPKWMNVQFLKKKIKIPYLYRRRVAREELQKKEFGSFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN34</accession>
    <name>A0A1J1GN34_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA-processing protein 7 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00158100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RRP7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526694.1">
        <property type="nucleotide sequence ID" value="XM_028675132.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN34"/>
    <dbReference type="GeneID" id="39730106"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00158100"/>
    <dbReference type="OMA" id="KFAYCAY"/>
    <dbReference type="OrthoDB" id="370341at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032545">
        <property type="term" value="C:CURI complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034456">
        <property type="term" value="C:UTP-C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040446">
        <property type="entry name" value="RRP7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024326">
        <property type="entry name" value="RRP7_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13191">
        <property type="entry name" value="RIBOSOMAL RNA PROCESSING PROTEIN 7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13191:SF0">
        <property type="entry name" value="RIBOSOMAL RNA-PROCESSING PROTEIN 7 HOMOLOG A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12923">
        <property type="entry name" value="RRP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RRM" evidence="2">
        <location>
            <begin position="47"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal RNA-processing protein 7 C-terminal" evidence="3">
        <location>
            <begin position="163"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="247" mass="29831" checksum="398553659F509871" modified="2017-02-15" version="1">MRNILKHFNILNISAEDNPFITLNLLIADCKDISNNNEFYDETLCVAILDNIISEKELKTFFSKFGRIKSFNILERKHLSTNFKNFVFCVYITYEEKNIIENILSYSVHINDYFKQKNQAPFIINFEKKNFLYFVKKYYDNYYNLYNGRKIIINDILNLCKENKVKKKLDVVDEDGFTVVQRSSDKPEFMNSIFSSKNEKFNYFKKKKKKKVHENFYLFRKKENFKNTNDTFKKKKINIKKKMIKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN99</accession>
    <name>A0A1J1GN99_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Branchpoint-bridging protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PGAL8A_00152100</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the BBP/SF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526633.1">
        <property type="nucleotide sequence ID" value="XM_028675064.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN99"/>
    <dbReference type="GeneID" id="39730045"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00152100"/>
    <dbReference type="OMA" id="EANMPKH"/>
    <dbReference type="OrthoDB" id="6777263at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045131">
        <property type="term" value="F:pre-mRNA branch point binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048024">
        <property type="term" value="P:regulation of mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02395">
        <property type="entry name" value="KH-I_BBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.10:FF:000073">
        <property type="entry name" value="Transcription or splicing factor-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045071">
        <property type="entry name" value="BBP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055256">
        <property type="entry name" value="KH_1_KHDC4/BBP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032570">
        <property type="entry name" value="SF1-HH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047086">
        <property type="entry name" value="SF1-HH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11208">
        <property type="entry name" value="RNA-BINDING PROTEIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11208:SF45">
        <property type="entry name" value="SPLICING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22675">
        <property type="entry name" value="KH-I_KHDC4-BBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16275">
        <property type="entry name" value="SF1-HH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 11" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8 11" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="11" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="6 11" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="K Homology" evidence="13">
        <location>
            <begin position="156"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="14">
        <location>
            <begin position="277"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="14">
        <location>
            <begin position="306"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="382"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="595"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="402"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="607"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU367126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG93812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="619" mass="71547" checksum="DD452CA46F223AE6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNA1</accession>
    <name>A0A1J1GNA1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RWD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00162300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526735.1">
        <property type="nucleotide sequence ID" value="XM_028675177.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNA1"/>
    <dbReference type="GeneID" id="39730148"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00162300"/>
    <dbReference type="OMA" id="GIIICEG"/>
    <dbReference type="OrthoDB" id="432412at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd24163">
        <property type="entry name" value="RWDD2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017359">
        <property type="entry name" value="Phi-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010541">
        <property type="entry name" value="Prp3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059181">
        <property type="entry name" value="RWDD2A-B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15955">
        <property type="entry name" value="RWD DOMAIN CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15955:SF8">
        <property type="entry name" value="RWD DOMAIN-CONTAINING PROTEIN 2B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06544">
        <property type="entry name" value="Prp3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RWD" evidence="2">
        <location>
            <begin position="62"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="373" mass="43809" checksum="D71B6AACEF218CFC" modified="2017-02-15" version="1">MLHNKKASDNELSQKKKKSGGTNSKEIKIESLKENIAKEDTYNIEEKKRKEILMKCEELQKKELEALKLIYVLNGELNIKNENDKEKHTIIHIQLNDQNINDNIINLTFELPKDYPLNSFLIINICVKNFSTDMNNYINDQIYKYIQNYFEQECILHIIYKVNELVENIQNKKEVIDNSDSSSDEKIGKDDKNSQELINNIPLLYYKMPYSHQSRILSRRLCYSHHILSLIKRSYILKWAKELNIGGYSKIGYPGIIICEGPKEEVDFYINSLNKLRWKHFDCRGMEDIKLNEYEDLDEARVLPKSMYELDSKGMSTLSNICTECGLRDLFLTSMKIYNTNGKHVKSEKSKNLDKNNEENLKINNKGKKKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNA6</accession>
    <name>A0A1J1GNA6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00156900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526682.1">
        <property type="nucleotide sequence ID" value="XM_028675119.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNA6"/>
    <dbReference type="GeneID" id="39730094"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00156900"/>
    <dbReference type="OMA" id="EMILYGA"/>
    <dbReference type="OrthoDB" id="392543at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026898">
        <property type="entry name" value="PrsW"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36844">
        <property type="entry name" value="PROTEASE PRSW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36844:SF1">
        <property type="entry name" value="PROTEASE PRSW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13367">
        <property type="entry name" value="PrsW-protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="273"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="306"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="336" mass="40302" checksum="536759D5975B0FE6" modified="2017-02-15" version="1">MLFEKLRNNNYGDENEKNIKWFCFMKYIRLFYCFCSVIFLVGFSYTINGNRGIIYLVFSFFPSFFYLYLFKRKIRRKINILNIIEMILYGSTISTFFASFLEYFLTFYFFYFCSICLMKEINESLLFVCSIILFFYFFFIIAYVEEISKIIPMIFIHRNIERNGNDYTEIPLFDRNTYLIENIYEEECEKKETKIKKFKYINVNDILEFIFFSLCSSAGFSSTENLFYSSHTTKENFVSILILRNLTCVLFHMCCSGLSSYNLFNYLNNKNRSFLNFIGILSSLFTASLFHAVYNYSIYFASLNIPIYQIFFLTILFIYCFLSILLMFFSVVKSII</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNA8</accession>
    <name>A0A1J1GNA8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DnaJ protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00157700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526690.1">
        <property type="nucleotide sequence ID" value="XM_028675128.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNA8"/>
    <dbReference type="GeneID" id="39730102"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00157700"/>
    <dbReference type="OMA" id="NIYESFF"/>
    <dbReference type="OrthoDB" id="550424at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000013">
        <property type="entry name" value="DnaJ subfamily B member 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.230.10">
        <property type="entry name" value="Heat shock protein DnaJ, cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044713">
        <property type="entry name" value="DNJA1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43888">
        <property type="entry name" value="DNAJ-LIKE-2, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012068587" evidence="1">
        <location>
            <begin position="22"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="46"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="378" mass="44516" checksum="6BC0691425D03F92" modified="2017-02-15" version="1">MIKSKFFLVFLIFLIFKTIKINEKSKIFISAWYNDEEQDDDYDHMKLYDVLGVQKNASLDEIKKAYRKLSKKYHPDKAKDKNSNNRFNEIVEAYEILSDDEKRKMYDYHGLNAAKNLESNKMEEDPSDHFNIYESFFGGGFRRDEQKKVENLILNIEIDLEQLYNGELFSVFYTRDINCLRSDDCIEKRRECSGKGYKTVTQQVAPGFIMQNKIKDESCIDRGKAWKYKCTYCPNGMKEEKTIKLTLEIEKGMKTNDKIVFEKKGKQEIGYENGDIVFIIQTKKHKIYERKNNDLHQLYEISLKDALIGFSKDIDHISGTPINVSKQTVTFHNEILKIKDKGMPIKNTNKFGDLYIKFLIQFPKKLTEEQKKVISEML</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNG9</accession>
    <name>A0A1J1GNG9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Ubiquitin-60S ribosomal protein L40, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PGAL8A_00172400</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the 60S subunit of the ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Part of the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the N-terminal section; belongs to the ubiquitin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526838.1">
        <property type="nucleotide sequence ID" value="XM_028670047.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNG9"/>
    <dbReference type="GeneID" id="39730251"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00172400"/>
    <dbReference type="OMA" id="CGRCSQL"/>
    <dbReference type="OrthoDB" id="428577at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01803">
        <property type="entry name" value="Ubl_ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000158">
        <property type="entry name" value="Polyubiquitin 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1060.50:FF:000001">
        <property type="entry name" value="ubiquitin-60S ribosomal protein L40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001975">
        <property type="entry name" value="Ribosomal_eL40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038587">
        <property type="entry name" value="Ribosomal_eL40_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019954">
        <property type="entry name" value="Ubiquitin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01020">
        <property type="entry name" value="Ribosomal_L40e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01377">
        <property type="entry name" value="Ribosomal_L40e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00299">
        <property type="entry name" value="UBIQUITIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="9 14" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="8" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="13">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00035124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG94017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="128" mass="14603" checksum="769C2AFEA5EAD858" modified="2017-02-15" version="1">MQIFVKTLTGKTITLDVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAIEPSLAQLAQKYNCQKLICRKCYARLHPRATNCRNKKCGRSNQLRPKKKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNM6</accession>
    <name>A0A1J1GNM6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Cyclin-dependent kinase 2 homolog</fullName>
            <ecNumber evidence="5">2.7.11.22</ecNumber>
            <ecNumber evidence="4">2.7.11.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="20">Cell division control protein 2 homolog</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="21">cdc2-related kinase 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="28" type="ORF">PGAL8A_00163300</name>
    </gene>
    <organism evidence="28 29">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="28" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="28">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="23">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="22">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="24">
            <text>[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10216"/>
            <dbReference type="Rhea" id="RHEA-COMP:11321"/>
            <dbReference type="Rhea" id="RHEA-COMP:11322"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43176"/>
            <dbReference type="ChEBI" id="CHEBI:68546"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="18">May form a complex composed of at least the catalytic subunit CRK2 and a cyclin.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="28">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="5"/>
    <dbReference type="EC" id="2.7.11.23" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526745.1">
        <property type="nucleotide sequence ID" value="XM_028675188.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNM6"/>
    <dbReference type="GeneID" id="39730158"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00163300"/>
    <dbReference type="OMA" id="YLYQITR"/>
    <dbReference type="OrthoDB" id="1732493at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008353">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07829">
        <property type="entry name" value="STKc_CDK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000396">
        <property type="entry name" value="Cdc2-related kinase 2, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000184">
        <property type="entry name" value="cyclin-dependent kinase 5 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF46">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15 25 26" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="17" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="9" id="KW-0132">Cell division</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14 28" id="KW-0418">Kinase</keyword>
    <keyword evidence="16" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0498">Mitosis</keyword>
    <keyword evidence="12 25 26" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="29" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 26" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="27">
        <location>
            <begin position="4"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="binding site" evidence="25">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00038543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00039612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00041902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00042858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00049280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="27">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="EMBL" id="CRG93924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="29">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="288" mass="32991" checksum="923675AEC14C18E9" modified="2017-02-15" version="1">MEKYHGLEKIGEGTYGVVYKAQNNYGETFALKKIRLEKEDEGIPSTAIREISILKELKHSNIVKLYDVIHTKKRLILVFEHLDQDLKKLLDVCDGGLESVTAKSFLLQLLNGIAYCHEHRVLHRDLKPQNLLINREGELKIADFGLARAFGIPVRKYTHEVVTLWYRAPDVLMGSKKYSTTIDIWSVGCIFAEMVNGRPLFPGVSETDQLMRIFKILGTPNSQNWPSVTELPKYDPNFTVYEPLPWESFLKGLDESGIDLLSKMLKLDPNQRITAKQALEHAYFKENN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPS5</accession>
    <name>A0A1J1GPS5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00190400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000027">
        <property type="protein sequence ID" value="CRG94507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527324.1">
        <property type="nucleotide sequence ID" value="XM_028670586.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730429"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00190400"/>
    <dbReference type="OMA" id="IHMILLE"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="691"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="323"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="378"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="504"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
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            <begin position="883"/>
            <end position="910"/>
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    <feature type="coiled-coil region" evidence="1">
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            <begin position="1068"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1186"/>
            <end position="1217"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1489"/>
            <end position="1523"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1609"/>
            <end position="1640"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1912"/>
            <end position="1946"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="329"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="378"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="508"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2090" mass="249758" checksum="E039D616F91DD41C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPX7</accession>
    <name>A0A1J1GPX7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00189800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000026">
        <property type="protein sequence ID" value="CRG94501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527319.1">
        <property type="nucleotide sequence ID" value="XM_028670581.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPX7"/>
    <dbReference type="GeneID" id="39730423"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00189800"/>
    <dbReference type="OMA" id="FPFGKND"/>
    <dbReference type="OrthoDB" id="2015333at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="283" mass="32890" checksum="E80135935C04272E" modified="2017-02-15" version="1" fragment="single">VNNLRSMFRREEKNNITDSAKNERDLKRQKFLGQGKKEKGENITESEPKKEITDNITESEPKKEITDNITESEPKKEITDNITESEPKKEITDNITESEPKKEITDNITESEPKKEVTDNITESEPKIEITDNITESEPKKEITDNITESEPKKEITDNITESEPKKEMRDNITESKPKKEITDNITESEPKKEITDNITESEPKKEITDNITESEPRKEITDNITESKPKKEIKDNITESEPKKEMRVNITESEPKKEQEKNKKKHKKLNILKFPFGKNDNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPY4</accession>
    <name>A0A1J1GPY4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DNA repair metallo-beta-lactamase protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00197000</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527390.1">
        <property type="nucleotide sequence ID" value="XM_028670660.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPY4"/>
    <dbReference type="GeneID" id="39730497"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00197000"/>
    <dbReference type="OrthoDB" id="262529at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035312">
        <property type="term" value="F:5'-3' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011084">
        <property type="entry name" value="DRMBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23240:SF6">
        <property type="entry name" value="DNA CROSS-LINK REPAIR 1A PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23240">
        <property type="entry name" value="DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07522">
        <property type="entry name" value="DRMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="8">
        <location>
            <begin position="3"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="480"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="149"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="763" mass="92151" checksum="D54B0445ACD39029" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ15</accession>
    <name>A0A1J1GQ15_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HotDog ACOT-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00408600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the acyl coenzyme A hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527203.1">
        <property type="nucleotide sequence ID" value="XM_028670452.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ15"/>
    <dbReference type="GeneID" id="39732616"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00408600"/>
    <dbReference type="OMA" id="FYCKDSY"/>
    <dbReference type="OrthoDB" id="331699at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047617">
        <property type="term" value="F:fatty acyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006637">
        <property type="term" value="P:acyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12655">
        <property type="entry name" value="ACYL-COA THIOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12655:SF0">
        <property type="entry name" value="ACYL-COENZYME A THIOESTERASE 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="533" mass="63134" checksum="4EDC5D10282F8033" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ54</accession>
    <name>A0A1J1GQ54_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">2-oxoglutarate dehydrogenase, mitochondrial</fullName>
            <ecNumber evidence="3">1.2.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">2-oxoglutarate dehydrogenase complex component E1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00113700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the alpha-ketoglutarate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.2" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526253.1">
        <property type="nucleotide sequence ID" value="XM_028674165.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ54"/>
    <dbReference type="GeneID" id="39729662"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00113700"/>
    <dbReference type="OMA" id="RDSYCRT"/>
    <dbReference type="OrthoDB" id="413077at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045252">
        <property type="term" value="C:oxoglutarate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004591">
        <property type="term" value="F:oxoglutarate dehydrogenase (succinyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02016">
        <property type="entry name" value="TPP_E1_OGDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12470:FF:000003">
        <property type="entry name" value="2-oxoglutarate dehydrogenase E1 component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11610">
        <property type="entry name" value="Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1150">
        <property type="entry name" value="TPP helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032106">
        <property type="entry name" value="2-oxogl_dehyd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011603">
        <property type="entry name" value="2oxoglutarate_DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042179">
        <property type="entry name" value="KGD_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031717">
        <property type="entry name" value="ODO-1/KGD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00239">
        <property type="entry name" value="2oxo_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006914">
        <property type="entry name" value="PRK09404.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008907">
        <property type="entry name" value="PRK12270.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152:SF4">
        <property type="entry name" value="2-OXOADIPATE DEHYDROGENASE COMPLEX COMPONENT E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152">
        <property type="entry name" value="2-OXOGLUTARATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16078">
        <property type="entry name" value="2-oxogl_dehyd_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16870">
        <property type="entry name" value="OxoGdeHyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000157">
        <property type="entry name" value="Oxoglu_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="9">
        <location>
            <begin position="648"/>
            <end position="858"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00040267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00042984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG93431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1036" mass="120467" checksum="F36D0AADC47EE718" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ59</accession>
    <name>A0A1J1GQ59_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00179500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527227.1">
        <property type="nucleotide sequence ID" value="XM_028670479.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ59"/>
    <dbReference type="GeneID" id="39730322"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00179500"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="148" mass="16874" checksum="C8D459994C9CF3A8" modified="2017-02-15" version="1">MKPFINHSLYVQNVTANVTSNNTNNSIYTSTFPLLIAFLVGASLLLIIFLFIIHYKKGNSMNFIITPSDIPYELLESNIQLNNVCNRTNNSLCSIVFENNLSNALTEKSEEKEINIKTKSDIAIIREKLKSRIIIETYIIIIDKCKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ79</accession>
    <name>A0A1J1GQ79_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA helicase MCM9, putative</fullName>
            <ecNumber evidence="7">3.6.4.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MCM9</name>
        <name evidence="7" type="ORF">PGAL8A_00089800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526016.1">
        <property type="nucleotide sequence ID" value="XM_028671533.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ79"/>
    <dbReference type="GeneID" id="39729422"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00089800"/>
    <dbReference type="OMA" id="CCIDEFC"/>
    <dbReference type="OrthoDB" id="331858at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF48">
        <property type="entry name" value="DNA HELICASE MCM9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="6">
        <location>
            <begin position="615"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="209"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1104" mass="130218" checksum="F843F3BFDEBF2BDB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQE6</accession>
    <name>A0A1J1GQE6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcription initiation factor IIF subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00206400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527482.1">
        <property type="nucleotide sequence ID" value="XM_028670762.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQE6"/>
    <dbReference type="GeneID" id="39730591"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00206400"/>
    <dbReference type="OMA" id="NWDYNND"/>
    <dbReference type="OrthoDB" id="343414at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="521" mass="61304" checksum="B481251C2F94111C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQF4</accession>
    <name>A0A1J1GQF4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00189200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000026">
        <property type="protein sequence ID" value="CRG94497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527315.1">
        <property type="nucleotide sequence ID" value="XM_028670576.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQF4"/>
    <dbReference type="GeneID" id="39730419"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00189200"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47239">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47239:SF1">
        <property type="entry name" value="EXTENSIN-3-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013244169" evidence="2">
        <location>
            <begin position="23"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="450" mass="53129" checksum="864BC078B7442FE8" modified="2017-02-15" version="1">MITLTLYLKITAFLLLIWMYQCFYNCDSYKSLIDKNILQTKNKLKYERVLTEGDIVGNKQTNDKGCLEECPLDNEKNNWENPVQNENPCDRWKRKTNPLFRKIFNKKTSEMDPEWRDQKWNNEWNKISANKVNELSSIFYRSDISEEEKKKLIRNVKDELDMEFWTFLDECKKEMRDNKTESESKKEMIDNKTESESMKETIDNKTESESMKETIDNKTESESMKETIDNKTESESMKETIDNKIESESKKEMIDNKTESESMKETIDNKTESESMKETIDNKTESESMKETIDNKTESESMKETIDNKTESESMKETIDNKTESESMKETIDNKTESESMKETIDNKTESESMKETIDNKTESESMKELIDSKTESESKKEMRENRTESESTKEMRDNKKESESTKEKGTNEIKNYKKKISKLIIVLIFLRRIEYNGLTENIGGVMHKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQK2</accession>
    <name>A0A1J1GQK2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Proteasome subunit alpha type-1, putative</fullName>
            <ecNumber evidence="9">3.4.25.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00196500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase T1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.25.1" evidence="9"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527385.1">
        <property type="nucleotide sequence ID" value="XM_028670654.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQK2"/>
    <dbReference type="GeneID" id="39730492"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00196500"/>
    <dbReference type="OMA" id="NTQVYGK"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03749">
        <property type="entry name" value="proteasome_alpha_type_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000063">
        <property type="entry name" value="Proteasome subunit alpha type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035144">
        <property type="entry name" value="Proteasome_alpha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4 6 9" id="KW-0647">Proteasome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="8">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="237"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="266" mass="30361" checksum="529BDD3AEFFD766C" modified="2017-02-15" version="1">MYRNLYDTDNIIYSPEGRLYQIEYANEAIKQGTCAVAIKSKDFVVVCGLKKCISKLSYHQEKLFKIDDYIGVTMSGITSDAKVLTKFMRNECLTHKFLYDENINIEKLVKKVADKYQRNTQKSSRRAFGVGLIIAGYDKEPFIFETKPNGSYFEYIAISFGARSHASKTYLEKNVHLFEESNLDDLILHCLKALKSSLSSENELTVDNTSLAIVGKDKPWDEISPLELVSYLTKINNEAQNEQNQTGDQNETSQSNDQNQKNEQVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQP7</accession>
    <name>A0A1J1GQP7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transcription factor with AP2 domain(S), putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ApiAP2</name>
        <name evidence="8" type="ORF">PGAL8A_00225800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527676.1">
        <property type="nucleotide sequence ID" value="XM_028670978.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQP7"/>
    <dbReference type="GeneID" id="39730785"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00225800"/>
    <dbReference type="OrthoDB" id="333966at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00847">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="7">
        <location>
            <begin position="62"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="329"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="565"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="662"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="575"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="687"/>
            <end position="697"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="741" mass="85050" checksum="15D6EC3DB42F7E73" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQR5</accession>
    <name>A0A1J1GQR5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Dynein beta chain, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">PGAL8A_00225200</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527670.1">
        <property type="nucleotide sequence ID" value="XM_028670970.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730779"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00225200"/>
    <dbReference type="OrthoDB" id="5593012at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097729">
        <property type="term" value="C:9+2 motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036157">
        <property type="term" value="C:outer dynein arm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008569">
        <property type="term" value="F:minus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060294">
        <property type="term" value="P:cilium movement involved in cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036158">
        <property type="term" value="P:outer dynein arm assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.20:FF:000001">
        <property type="entry name" value="dynein heavy chain 2, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.180.20">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.720">
        <property type="entry name" value="Region D6 of dynein motor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035699">
        <property type="entry name" value="AAA_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041658">
        <property type="entry name" value="AAA_lid_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042219">
        <property type="entry name" value="AAA_lid_11_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054354">
        <property type="entry name" value="DYNC2H1-like_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043157">
        <property type="entry name" value="Dynein_AAA1S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041466">
        <property type="entry name" value="Dynein_AAA5_ext"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041228">
        <property type="entry name" value="Dynein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043160">
        <property type="entry name" value="Dynein_C_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042228">
        <property type="entry name" value="Dynein_linker_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10676:SF365">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10676">
        <property type="entry name" value="DYNEIN HEAVY CHAIN FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12774">
        <property type="entry name" value="AAA_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12775">
        <property type="entry name" value="AAA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18198">
        <property type="entry name" value="AAA_lid_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22597">
        <property type="entry name" value="DYN_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17852">
        <property type="entry name" value="Dynein_AAA_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18199">
        <property type="entry name" value="Dynein_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-0243">Dynein</keyword>
    <keyword evidence="3" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8" id="KW-0505">Motor protein</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynein heavy chain hydrolytic ATP-binding dynein motor region" evidence="12">
        <location>
            <begin position="2283"/>
            <end position="2400"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain hydrolytic ATP-binding dynein motor region" evidence="12">
        <location>
            <begin position="2530"/>
            <end position="2742"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain AAA 5 extension" evidence="13">
        <location>
            <begin position="3033"/>
            <end position="3150"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein 2 heavy chain 1 cytoplasmic ATPase lid" evidence="16">
        <location>
            <begin position="3601"/>
            <end position="3683"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain AAA lid" evidence="14">
        <location>
            <begin position="5843"/>
            <end position="5981"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain C-terminal" evidence="15">
        <location>
            <begin position="6019"/>
            <end position="6298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="2009"/>
            <end position="2197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="4017"/>
            <end position="4063"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="5282"/>
            <end position="5425"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="213"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="1132"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="4414"/>
            <end position="4441"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="4484"/>
            <end position="4582"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="4697"/>
            <end position="4738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="2026"/>
            <end position="2043"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="2059"/>
            <end position="2071"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="2072"/>
            <end position="2131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="2132"/>
            <end position="2164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="2165"/>
            <end position="2175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="2176"/>
            <end position="2187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="2188"/>
            <end position="2197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="4017"/>
            <end position="4032"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="4049"/>
            <end position="4063"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="5282"/>
            <end position="5299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="5305"/>
            <end position="5371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="5385"/>
            <end position="5403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="5410"/>
            <end position="5423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF12774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF17852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF18198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF18199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF22597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="CRG94855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="6302" mass="750961" checksum="850AFB9483DDF5E4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQU0</accession>
    <name>A0A1J1GQU0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00205500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527473.1">
        <property type="nucleotide sequence ID" value="XM_028670751.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQU0"/>
    <dbReference type="GeneID" id="39730582"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00205500"/>
    <dbReference type="OMA" id="KFNTIKW"/>
    <dbReference type="OrthoDB" id="346562at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36329">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36329:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="5"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="770"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="811"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="843"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="877"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="901"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="954"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="982"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1111" mass="133957" checksum="B4D3AF4F31377010" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRC4</accession>
    <name>A0A1J1GRC4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD-dependent protein deacylase</fullName>
            <ecNumber evidence="3">2.3.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Regulatory protein SIR2 homolog 5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00241100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the sirtuin family. Class III subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527826.1">
        <property type="nucleotide sequence ID" value="XM_028671145.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRC4"/>
    <dbReference type="GeneID" id="39730939"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00241100"/>
    <dbReference type="OMA" id="LIHMHGE"/>
    <dbReference type="OrthoDB" id="424302at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017136">
        <property type="term" value="F:histone deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036054">
        <property type="term" value="F:protein-malonyllysine demalonylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036055">
        <property type="term" value="F:protein-succinyllysine desuccinylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01407">
        <property type="entry name" value="SIR2-fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="entry name" value="SIR2/SIRT2 'Small Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01121">
        <property type="entry name" value="Sirtuin_ClassIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027546">
        <property type="entry name" value="Sirtuin_class_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF10">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2 3" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="5">
        <location>
            <begin position="11"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3 4">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="114"/>
            <end position="117"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="207"/>
            <end position="209"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="233"/>
            <end position="235"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="266" mass="29991" checksum="3169B051DD624DA1" modified="2017-02-15" version="1">MGNLMIFTLKKETKNMTLEELAELIKNSKYVVALTGSGTSAESNIPSFRGSINSIWNKYDPRIYGTIWGFWKYPEKIWEVIRDISSDYDIELNNGHIALSTLENLGYLKSVITQNIDGLHEESGNTKVIPLHGNVFEACCCTCNKIVKLNKIMLQKTSHFMHQLPPECPCGGIFKPNVVLFGEVIPKDLLKEAEKEIAKCDILLVIGTSSTVSTATNLCYFANKKKKKIVEINISKTYITNKMSDYHVCAKFSQLIKVTNILKEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRH8</accession>
    <name>A0A1J1GRH8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Inner centromere protein ARK-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00251500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the INCENP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527926.1">
        <property type="nucleotide sequence ID" value="XM_028671256.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRH8"/>
    <dbReference type="GeneID" id="39731043"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00251500"/>
    <dbReference type="OMA" id="EINESSC"/>
    <dbReference type="OrthoDB" id="339519at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005819">
        <property type="term" value="C:spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005635">
        <property type="entry name" value="Inner_centromere_prot_ARK-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03941">
        <property type="entry name" value="INCENP_ARK-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inner centromere protein ARK-binding" evidence="7">
        <location>
            <begin position="903"/>
            <end position="940"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1200" mass="144445" checksum="AE1F7E24F3575830" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRS6</accession>
    <name>A0A1J1GRS6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00237900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527795.1">
        <property type="nucleotide sequence ID" value="XM_028671110.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRS6"/>
    <dbReference type="GeneID" id="39730907"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00237900"/>
    <dbReference type="OMA" id="EKNFFNC"/>
    <dbReference type="OrthoDB" id="387690at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="619"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="619"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="633"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="986" mass="117248" checksum="2915BE871C8B155C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRZ1</accession>
    <name>A0A1J1GRZ1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PIR-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00178400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000021">
        <property type="protein sequence ID" value="CRG94072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526893.1">
        <property type="nucleotide sequence ID" value="XM_028670108.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRZ1"/>
    <dbReference type="GeneID" id="39730311"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00178400"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="219"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="272"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="354" mass="39505" checksum="55FC23CB2987BFD5" modified="2017-02-15" version="1">MLNYSIIIFYFSFLINNINLKTEKFFTTWRTLAEEQATAPLIRMARSTSTMEGRLNRWLDFIQEEFFSNIDKFKSNSTGTDAAIQWVKDKTNILMHALNSTNDTQDRNLLSQTLTSWNELARKLLNSTLGLDFSNGSSSSNSTGSSNLPNMSTPLSTLSSFPATDVSTGVEKITTILSENSTGIPGLLSTTSSGIAQESSLGYSISEGCSSIFCGSTTIALSLPFVIIGGLLFFVYLYKFTCFGSFLGRSNIKKERRKRRIYNVSMENIEDPYESSQETESMKSTLESSEETEAKRSKLESSEETETKGSRLENSKKTGAMRSGFNSLARAFGYKYRNIFPYVDSNSYENETAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS77</accession>
    <name>A0A1J1GS77_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA-(apurinic or apyrimidinic site) endonuclease</fullName>
            <ecNumber evidence="8">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00004900</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="6 8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="6 8">Probably binds two magnesium or manganese ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the DNA repair enzymes AP/ExoA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528095.1">
        <property type="nucleotide sequence ID" value="XM_028671443.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS77"/>
    <dbReference type="GeneID" id="39728571"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00004900"/>
    <dbReference type="OMA" id="CSSEILG"/>
    <dbReference type="OrthoDB" id="498125at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003906">
        <property type="term" value="F:DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008311">
        <property type="term" value="F:double-stranded DNA 3'-5' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004808">
        <property type="entry name" value="AP_endonuc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00633">
        <property type="entry name" value="xth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748">
        <property type="entry name" value="AP ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748:SF6">
        <property type="entry name" value="DNA-(APURINIC OR APYRIMIDINIC SITE) ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51435">
        <property type="entry name" value="AP_NUCLEASE_F1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 6 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="2 6 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="9">
        <location>
            <begin position="187"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="333"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="5">
        <location>
            <position position="372"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="502"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="372"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="374"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="501"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="502"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="374"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="7">
        <location>
            <position position="470"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA substrate" evidence="7">
        <location>
            <position position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604808-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR604808-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR604808-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG95284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="526" mass="62520" checksum="78879640E95F3C7A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS78</accession>
    <name>A0A1J1GS78_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00012200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528164.1">
        <property type="nucleotide sequence ID" value="XM_028671519.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS78"/>
    <dbReference type="GeneID" id="39728644"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00012200"/>
    <dbReference type="OMA" id="DSHWRNQ"/>
    <dbReference type="OrthoDB" id="372072at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="534" mass="62378" checksum="FD224D1DE68F3CC4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSB0</accession>
    <name>A0A1J1GSB0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Dynactin subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00257100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527979.1">
        <property type="nucleotide sequence ID" value="XM_028671315.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSB0"/>
    <dbReference type="GeneID" id="39731099"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00257100"/>
    <dbReference type="OMA" id="MNKHFLD"/>
    <dbReference type="OrthoDB" id="4977at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005869">
        <property type="term" value="C:dynactin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028133">
        <property type="entry name" value="Dynamitin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15346">
        <property type="entry name" value="DYNACTIN SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04912">
        <property type="entry name" value="Dynamitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="625"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="68"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="88"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="691" mass="81690" checksum="277177DB53B0262C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSE3</accession>
    <name>A0A1J1GSE3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">5'-3' exonuclease, N-terminal resolvase-like domain, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00020400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528246.1">
        <property type="nucleotide sequence ID" value="XM_028671611.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSE3"/>
    <dbReference type="GeneID" id="39728726"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00020400"/>
    <dbReference type="OMA" id="CQPNRKY"/>
    <dbReference type="OrthoDB" id="275278at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008409">
        <property type="term" value="F:5'-3' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033567">
        <property type="term" value="P:DNA replication, Okazaki fragment processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09898">
        <property type="entry name" value="H3TH_53EXO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09859">
        <property type="entry name" value="PIN_53EXO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020046">
        <property type="entry name" value="5-3_exonucl_a-hlix_arch_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002421">
        <property type="entry name" value="5-3_exonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020045">
        <property type="entry name" value="DNA_polI_H3TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038969">
        <property type="entry name" value="FEN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42646:SF2">
        <property type="entry name" value="5'-3' EXONUCLEASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42646">
        <property type="entry name" value="FLAP ENDONUCLEASE XNI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01367">
        <property type="entry name" value="5_3_exonuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02739">
        <property type="entry name" value="5_3_exonuc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00475">
        <property type="entry name" value="53EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012000758" evidence="4">
        <location>
            <begin position="22"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="5'-3' exonuclease" evidence="5">
        <location>
            <begin position="80"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="426" mass="50553" checksum="9C00E6E75AE55195" modified="2017-02-15" version="1">MNKKFFIIIISIKYFLLCSKAKIKKNKYIFYRKNLNNLFFLKSSVREFLSINKFLLKRKSISKINVKRKKNDENVGKIKNYETFLIVDGSSILYKNFFGMPILKNDNEINLSTIYGFIQSLNKIYNLFSPSYVVIVFDSKTSNDNKKKIYSKYKIYRKKNPEEIYEQLKIVSDFCDLIGIKTISSTNVESDNYIASIVDNIYNTIKNKTLNIYKNDDEDNRIINENSNDIEKIKEEDEITKANEDKKKNDYENELRVVVVSSDKDLLQLLEYNYNNNLNNMKIYICQPNKKYRLVDSNLFYEEYNIMPHQYCDYLILSGDKTDGISGVPNIGDKTSKYLLKEFYNIDNILKNLHKLPNKLHNILLNNIENINIFRKLIKLKCETNQSLVLNDYKQKNIKNFEKFQNFVDKYSLHKLLRKSIIINYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSF1</accession>
    <name>A0A1J1GSF1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cyclic amine resistance locus protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CARL</name>
        <name evidence="8" type="ORF">PGAL8A_00394400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAPT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527061.1">
        <property type="nucleotide sequence ID" value="XM_028670294.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSF1"/>
    <dbReference type="GeneID" id="39732474"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00394400"/>
    <dbReference type="OMA" id="IYINIAH"/>
    <dbReference type="OrthoDB" id="29023at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008010">
        <property type="entry name" value="Tatp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13317">
        <property type="entry name" value="TRANSMEMBRANE ANTERIOR POSTERIOR TRANSFORMATION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13317:SF4">
        <property type="entry name" value="TRANSMEMBRANE ANTERIOR POSTERIOR TRANSFORMATION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05346">
        <property type="entry name" value="DUF747"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="678"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="892"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="922"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="999"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1105"/>
            <end position="1132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1153" mass="138671" checksum="2F77A0A7E97400A7" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSJ3</accession>
    <name>A0A1J1GSJ3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00172600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526840.1">
        <property type="nucleotide sequence ID" value="XM_028670049.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSJ3"/>
    <dbReference type="GeneID" id="39730253"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00172600"/>
    <dbReference type="OMA" id="ETKNEYD"/>
    <dbReference type="OrthoDB" id="295355at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033362">
        <property type="entry name" value="SSNA1_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28661:SF1">
        <property type="entry name" value="MICROTUBULE NUCLEATION FACTOR SSNA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28661">
        <property type="entry name" value="SJOEGREN SYNDROME NUCLEAR AUTOANTIGEN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="20"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="127" mass="14966" checksum="2D105C5A0673E011" modified="2017-02-15" version="1">MDHEKPIPLIKNEDELSKCIEILRIKRQEIHEQILKEEDKERMQKEIAMLNEKLQKVCHSIAKKSQTRLEYDRTIKETSAAYSKIRESAKSLLHILKREENHLGSKLYSGVSEDDLKSLRELGNLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSJ4</accession>
    <name>A0A1J1GSJ4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PIR-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00264400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528051.1">
        <property type="nucleotide sequence ID" value="XM_028671394.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSJ4"/>
    <dbReference type="GeneID" id="39731173"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00264400"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="287"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="157"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="203"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="384" mass="42608" checksum="1C7A4F797BDF12D4" modified="2017-02-15" version="1">MTIYIYFLVCIFQYFYSINFEIGKNNLKTELCLRSGRILSEKQQGTRSRNVRSTRDIKSNLKFWLDTIEEGLFDEIEKLTNNFTVSNVRNFSQWMNHKSNIITRALNRIPDPTAKKFLNETLTSWRKLTDDIILNQISDTYIDRYFPSNFTNLNGSSSPSALSSASPSTSTLSSVSAASSNSTSFSSPTQLPSLTTLSIFNSSPESTVSPTTTFPSTLDLSPTTSSNSHIHTTTSSTNDTSDLPTLHSTNETNSTAALTINSASVIPVNNSGGLTSTTCTGLLCSPAFVALPVSVALLGGVLFFVLLYKYTPVGKFLGRDNPKKKKGKKRLHEIPMERINSPKLLKAKKTENVKRSRLDSFLRAFGYNKKFPYIDEDVTSDQVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSM1</accession>
    <name>A0A1J1GSM1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00020500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528247.1">
        <property type="nucleotide sequence ID" value="XM_028671612.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSM1"/>
    <dbReference type="GeneID" id="39728727"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00020500"/>
    <dbReference type="OMA" id="SYTFWDM"/>
    <dbReference type="OrthoDB" id="336008at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057221">
        <property type="entry name" value="DUF7899"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31789">
        <property type="entry name" value="OS05G0482600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31789:SF1">
        <property type="entry name" value="OS05G0482600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25463">
        <property type="entry name" value="DUF7899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="537" mass="62446" checksum="F1D60D5022A6F90B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSW7</accession>
    <name>A0A1J1GSW7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00011100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528155.1">
        <property type="nucleotide sequence ID" value="XM_028671509.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSW7"/>
    <dbReference type="GeneID" id="39728633"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00011100"/>
    <dbReference type="OMA" id="KFNERTD"/>
    <dbReference type="OrthoDB" id="446168at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="83"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="566" mass="68500" checksum="257BADF99AAB3E0C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSX4</accession>
    <name>A0A1J1GSX4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00012100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528163.1">
        <property type="nucleotide sequence ID" value="XM_028671518.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSX4"/>
    <dbReference type="GeneID" id="39728643"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00012100"/>
    <dbReference type="OrthoDB" id="10551895at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="271" mass="31435" checksum="74E29368C0C2853A" modified="2017-02-15" version="1">MNVKPTESYNENLRINEYDNIQNDKNNNSINLNKKDGDNKIIEDYNSGNSLISYSSKNKDQVESQKKRINVSSITISDEIENMIKEKSINTEEKSKTSYDNLNKNKKKNSKSSSDKLIKNIVVIGKSKTTPDKLYKNTNTTNKLKTTFSDQSYEQSKNKIKALKTIHLDKSFLLKSNIFSNNNKGASDDFFKNDDFITYSSDCKTLPTVNEEKLRIKSERTKKLIFQKNKKINRLAYSLDISKYNLNEKKKLTLKKCNSTYFNKRGIILYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSZ1</accession>
    <name>A0A1J1GSZ1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ABC transporter I family member 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SufC</name>
        <name evidence="4" type="ORF">PGAL8A_00285100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528462.1">
        <property type="nucleotide sequence ID" value="XM_028671850.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSZ1"/>
    <dbReference type="GeneID" id="39731384"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00285100"/>
    <dbReference type="OMA" id="MAMLEPK"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03217">
        <property type="entry name" value="ABC_FeS_Assembly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000405">
        <property type="entry name" value="Fe-S cluster assembly ATPase SufC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010230">
        <property type="entry name" value="FeS-cluster_ATPase_SufC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01978">
        <property type="entry name" value="sufC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43204">
        <property type="entry name" value="ABC TRANSPORTER I FAMILY MEMBER 6, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43204:SF1">
        <property type="entry name" value="ABC TRANSPORTER I FAMILY MEMBER 6, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="3">
        <location>
            <begin position="106"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="357" mass="40964" checksum="D9878B1D01E9148D" modified="2017-02-15" version="1">MYIKIYIIIAYGLLVLFDMIKCIYIEKSKNALKKCKKKKYNLNKKVNKIFFVVNKIKKTNLNKIKNLIKMENSNFDKDRLSLLKNLEEESNIVLQSPEWNEKCPLLEINNLHAIEIEGEKEILKGINLKIYLGEKHTIMGRNGSGKSTLAKVIAGHPYYKVTKGNMKFKGLDLNTLPVNVRSLCGIFLAFQYPVELPMVKNNEFLRAALNCHRRNRNETEISASEFNLLMINEIKKVGLSPDFLDRPVNYGFSGGEKKRNEILQMLILKPSFCILDETDSGLDVDSFKLTSSVISNFSNKNNSFLIVTHYKKLLELLKPNFIHIMHHGKIIESGDYSLVDKIESEGFSQFLKNSDTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT00</accession>
    <name>A0A1J1GT00_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Ribosome maturation protein SBDS, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00282500</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Associates with the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SDO1/SBDS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528436.1">
        <property type="nucleotide sequence ID" value="XM_028671822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT00"/>
    <dbReference type="GeneID" id="39731358"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00282500"/>
    <dbReference type="OMA" id="ENLMNEC"/>
    <dbReference type="OrthoDB" id="10253092at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042256">
        <property type="term" value="P:cytosolic ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1250.10">
        <property type="entry name" value="Ribosome maturation protein SBDS, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.900">
        <property type="entry name" value="SBDS protein C-terminal domain, subdomain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018023">
        <property type="entry name" value="Ribosome_mat_SBDS_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036786">
        <property type="entry name" value="Ribosome_mat_SBDS_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002140">
        <property type="entry name" value="Sdo1/SBDS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039100">
        <property type="entry name" value="Sdo1/SBDS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018978">
        <property type="entry name" value="SDO1/SBDS_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037188">
        <property type="entry name" value="Sdo1/SBDS_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019783">
        <property type="entry name" value="SDO1/SBDS_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00291">
        <property type="entry name" value="RNA_SBDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10927">
        <property type="entry name" value="RIBOSOME MATURATION PROTEIN SBDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10927:SF1">
        <property type="entry name" value="RIBOSOME MATURATION PROTEIN SBDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09377">
        <property type="entry name" value="SBDS_domain_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01172">
        <property type="entry name" value="SBDS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89895">
        <property type="entry name" value="FYSH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109728">
        <property type="entry name" value="Hypothetical protein AF0491, middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01267">
        <property type="entry name" value="UPF0023"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Ribosome maturation protein SDO1/SBDS N-terminal" evidence="10">
        <location>
            <begin position="15"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosome maturation protein SDO1/SBDS central" evidence="11">
        <location>
            <begin position="110"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="216"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="467"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="390"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="229"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="471"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="487"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF09377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG95628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="605" mass="71038" checksum="351191FADDD180DD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT79</accession>
    <name>A0A1J1GT79_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tetratricopeptide repeat family protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00292000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528524.1">
        <property type="nucleotide sequence ID" value="XM_028671919.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT79"/>
    <dbReference type="GeneID" id="39731453"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00292000"/>
    <dbReference type="OMA" id="NDLIYEC"/>
    <dbReference type="OrthoDB" id="433738at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45994">
        <property type="entry name" value="FI21225P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45994:SF1">
        <property type="entry name" value="FI21225P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="160"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1173" mass="138927" checksum="2689394FB65FDBA1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTB4</accession>
    <name>A0A1J1GTB4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Leucine-zipper-like transcriptional regulator 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00298600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528582.1">
        <property type="nucleotide sequence ID" value="XM_028671984.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTB4"/>
    <dbReference type="GeneID" id="39731519"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00298600"/>
    <dbReference type="OMA" id="WIELNTI"/>
    <dbReference type="OrthoDB" id="10251809at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23244">
        <property type="entry name" value="KELCH REPEAT DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23244:SF481">
        <property type="entry name" value="KELCH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="BTB" evidence="4">
        <location>
            <begin position="785"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="372"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="340"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="372"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="397"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="948" mass="111827" checksum="3EA1496DBBD10BA4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTF7</accession>
    <name>A0A1J1GTF7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mitochondrial ribosomal protein L17-2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00302600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528622.1">
        <property type="nucleotide sequence ID" value="XM_028672028.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTF7"/>
    <dbReference type="GeneID" id="39731559"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00302600"/>
    <dbReference type="OMA" id="LYRYRPF"/>
    <dbReference type="OrthoDB" id="275000at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1030.10:FF:000011">
        <property type="entry name" value="Ribosomal protein L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1030.10">
        <property type="entry name" value="Ribosomal protein L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000456">
        <property type="entry name" value="Ribosomal_bL17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036373">
        <property type="entry name" value="Ribosomal_bL17_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14413:SF16">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL17M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14413">
        <property type="entry name" value="RIBOSOMAL PROTEIN L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01196">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64263">
        <property type="entry name" value="Prokaryotic ribosomal protein L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="254" mass="30807" checksum="067B494DE6666DD1" modified="2017-02-15" version="1">MGYTSTLKFVNLGVKRRLFRRAHKQPHHKWDSIKNQLNDLLKYGRIETTLTKAKELQGYAEELIYLAKKDNVENNLKVESMLRTAQGRRRLYEYYVPLYRYRPFFFTRVVNQWRLRLRDSAPMAFIEFIDRPGELRPARPSGYDRIKYIFEEMKKNRRNFRKYFHIAKRFNLLDENNQLISNLHEHLISKNDNMWDSDDEDQIIVDPELIEKYKHLSEPMLKGPKKGREPFYVDLPIPSVAEREFLNYRKKFKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTL3</accession>
    <name>A0A1J1GTL3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00308200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528678.1">
        <property type="nucleotide sequence ID" value="XM_028672091.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTL3"/>
    <dbReference type="GeneID" id="39731615"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00308200"/>
    <dbReference type="OrthoDB" id="10421777at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="504"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="529"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="567"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="632"/>
            <end position="651"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="886" mass="107233" checksum="8678D6079C12041F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTQ8</accession>
    <name>A0A1J1GTQ8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metacaspase-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">MCA3</name>
        <name evidence="3" type="ORF">PGAL8A_00287800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C14B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528489.1">
        <property type="nucleotide sequence ID" value="XM_028671881.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731411"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00287800"/>
    <dbReference type="OrthoDB" id="3223806at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12660">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050452">
        <property type="entry name" value="Metacaspase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104:SF30">
        <property type="entry name" value="METACASPASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104">
        <property type="entry name" value="METACASPASE-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1439"/>
            <end position="1464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1529"/>
            <end position="1556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1448"/>
            <end position="1460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1531"/>
            <end position="1544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1545"/>
            <end position="1556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1717" mass="200766" checksum="F49BA3EBAAD13215" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTX4</accession>
    <name>A0A1J1GTX4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00311600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528711.1">
        <property type="nucleotide sequence ID" value="XM_028672127.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTX4"/>
    <dbReference type="GeneID" id="39731649"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00311600"/>
    <dbReference type="OrthoDB" id="372941at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="448" mass="53490" checksum="EA0E3FF7FAA511AA" modified="2017-02-15" version="1">MHDENKSIMKKGENEQDKFINRNNFNISNCTNIKDTNVENIDYWIQQKKYKELIKKIDDKNESNNKKNCGKNYIIYGDGLKGKNFNSKKLYKDLDKIKSDFINRKSSSEENLKDSKNNIQNYNNIEHYNIMSSTDPSLSSNNSITEMYETNYNYFTNFKGEMSELPISSYNLKIKSIPNHNINKYNNLLKNIYLNNKDIKTKKLYENISVNLKKKNENKIKKEYSNLQKYKDTLLYKSRYIYLKQIKSKNSLKKNGTNFNLNTHNNRNIQIKYEPINKLINKNILFLGSFNKMKNRTPHKIKYISKYKNHFKKVHHINESYLNGKFKKKRNNCIFLDQHNSKNIKSIKNYYIPFILQNIRKNQSILNDIINYSYIKNMKDENLLNNSIDYRPKKSKGIYRRITCKNKCVYTKNAFTNLMEKLKLLGYALFFCFFFTNKTKSTKDKANI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUE2</accession>
    <name>A0A1J1GUE2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4460 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00313400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528729.1">
        <property type="nucleotide sequence ID" value="XM_028672147.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUE2"/>
    <dbReference type="GeneID" id="39731667"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00313400"/>
    <dbReference type="OMA" id="PNLIFFH"/>
    <dbReference type="OrthoDB" id="423408at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028031">
        <property type="entry name" value="DUF4460"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027986">
        <property type="entry name" value="TCAIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31596">
        <property type="entry name" value="T-CELL ACTIVATION INHIBITOR, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31596:SF1">
        <property type="entry name" value="T-CELL ACTIVATION INHIBITOR, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14687">
        <property type="entry name" value="DUF4460"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4460" evidence="1">
        <location>
            <begin position="33"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="386" mass="46456" checksum="43568FC8885AEE35" modified="2017-02-15" version="1">MLIKFLNFFIKKNNYFQLKNYTFKFENKRNYDSRLFRKSVRKLLYFFYKEVHPDLTSNLPDDLKKVNNESLSVLNSYIDILSSSKKNENNIFLEKSLVFFKVFENSENKIIKGRYKNIIIKLPTISNNLSFDEKEKITAKLIYDIKNSLEKTKRKNIFNDDIEEIEITDNILSTKETKKRGDINNIWEDLTNHVKDTEALYQPCEEEIELKKKKKSYFYYIKKKLELKFQKINHKKRRKKKLQKINEIASKIVQEKFPYNNKNNYDQILINQSYQIIQNGFNPNLIFFHKDINEKEKRIGIENLCGMHLKDDADKWLLENCLKLLKNHKTPIPLVVYSEKKIQLSLTYGFIYIPYEFCLNDLFTFLEDNIDKARNIRKKVLESFEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUL7</accession>
    <name>A0A1J1GUL7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00336100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528951.1">
        <property type="nucleotide sequence ID" value="XM_028672394.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUL7"/>
    <dbReference type="GeneID" id="39731891"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00336100"/>
    <dbReference type="OMA" id="CVQKIKI"/>
    <dbReference type="OrthoDB" id="370551at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="164" mass="19543" checksum="0FDBB2F6F7647B07" modified="2017-02-15" version="1">MGNTTSKDEENQKRNLILLDDNFLHNFQKKDNTIFEKKLNNIEKDDNLHKNNIPTKINGSVKSTKSEDPLNYKGEEYDKLRKMVIDDLIIESEKYISMHKDKLNNINKDNLKIPQTNNECLYNENKIYDCLKNMNESTSDFINSYTRCYRYLRKYESCVQKIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUS4</accession>
    <name>A0A1J1GUS4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Transmembrane protein Tmp21 homologue, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00245500</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EMP24/GP25L family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527869.1">
        <property type="nucleotide sequence ID" value="XM_028671192.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUS4"/>
    <dbReference type="GeneID" id="39730983"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00245500"/>
    <dbReference type="OMA" id="TKDFAFM"/>
    <dbReference type="OrthoDB" id="759142at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015720">
        <property type="entry name" value="Emp24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009038">
        <property type="entry name" value="GOLD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22811">
        <property type="entry name" value="TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01105">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01190">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012272438" evidence="8">
        <location>
            <begin position="24"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="GOLD" evidence="9">
        <location>
            <begin position="25"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG95056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="214" mass="25197" checksum="17FDA3049D1E640A" modified="2017-02-15" version="1">MNKTNKMILFLLIVFLQVVLINGIEIYITLNSNKLKCIKERINKDTLVVGKVKTDNESYLVSLFIYDSDVSEKNFNYQPKLPIFESRNEHDIKTAFTTFFSTSYSFCLQNRSNKNMNVYLEIKHGTEARDYTRIAKTEHLNKASIYLKQIIDQMNNFHVNLKRIKAMEEKEKAASDKLNDTLMWFSIINIIIIFIAAIIQDFYFKKFFTSKKII</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUW4</accession>
    <name>A0A1J1GUW4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Iron-sulfur assembly protein, sufD, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00330700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528897.1">
        <property type="nucleotide sequence ID" value="XM_028672335.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731837"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00330700"/>
    <dbReference type="OMA" id="YKKNTQP"/>
    <dbReference type="OrthoDB" id="2510at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055346">
        <property type="entry name" value="Fe-S_cluster_assembly_SufBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000825">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037284">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43575">
        <property type="entry name" value="PROTEIN ABCI7, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43575:SF1">
        <property type="entry name" value="PROTEIN ABCI7, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01458">
        <property type="entry name" value="SUFBD_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101960">
        <property type="entry name" value="Stabilizer of iron transporter SufD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012904647" evidence="3">
        <location>
            <begin position="30"/>
            <end position="1319"/>
        </location>
    </feature>
    <feature type="domain" description="SUF system FeS cluster assembly SufBD core" evidence="4">
        <location>
            <begin position="1060"/>
            <end position="1287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="441"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="519"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="813"/>
            <end position="840"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1319" mass="156357" checksum="D4321A8E7D90113C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUY7</accession>
    <name>A0A1J1GUY7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SUEL-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00225400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527672.1">
        <property type="nucleotide sequence ID" value="XM_028670972.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUY7"/>
    <dbReference type="GeneID" id="39730781"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00225400"/>
    <dbReference type="OMA" id="NEGYQHY"/>
    <dbReference type="OrthoDB" id="368565at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012068591" description="SUEL-type lectin domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="312" mass="36514" checksum="FBF6ED8C5A48F2FB" modified="2017-02-15" version="1">MKLFLFFFFFFLFSLFKNNSSKDLSKREEDSSIFYYGFTNNEEYQHYMPSKYPNIQRDRDLIIMSCNKGYTVVIKRAYIIDLNDEEYDYTKIAQNICIKKEQCSIDVKKFKRNTNNNSIDSSSELRVEYICMSSQKPLYDGNIFHQGVTHKYLIVRNQSSACAQNNENVIKLESISKAIEVCTLNNCNYVVWDNEEKKAFICKEENNDNIIEKKNSVTYINPNYFYTYGYATFLNYMSVCDNIIKAVPYNLSMTKSVDVCSHLDCHYFTKSYPGSIRSLSNTRNGKSWFCKGFPTIIPMDGFITSVKLSKFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV41</accession>
    <name>A0A1J1GV41_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Structural maintenance of chromosome protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00358100</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529162.1">
        <property type="nucleotide sequence ID" value="XM_028672628.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732111"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00358100"/>
    <dbReference type="OMA" id="KHMDFQR"/>
    <dbReference type="OrthoDB" id="5575062at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008278">
        <property type="term" value="C:cohesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007062">
        <property type="term" value="P:sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1060.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010935">
        <property type="entry name" value="SMC_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
        <property type="entry name" value="SMC_hinge_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937:SF12">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06470">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00968">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75553">
        <property type="entry name" value="Smc hinge domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0498">Mitosis</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC hinge" evidence="8">
        <location>
            <begin position="834"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1319"/>
            <end position="1375"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="444"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="511"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="713"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="776"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1030"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1108"/>
            <end position="1293"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1385"/>
            <end position="1466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1324"/>
            <end position="1345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1365"/>
            <end position="1375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG96357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1637" mass="194280" checksum="30A02A2F5EC2B354" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVG8</accession>
    <name>A0A1J1GVG8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Vacuolar membrane protein-related, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00351800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529105.1">
        <property type="nucleotide sequence ID" value="XM_028672565.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVG8"/>
    <dbReference type="GeneID" id="39732048"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00351800"/>
    <dbReference type="OMA" id="NAWFFAK"/>
    <dbReference type="OrthoDB" id="754047at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="181"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="286"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="493" mass="59195" checksum="90A734569B30A4F9" modified="2017-02-15" version="1">MLKIKKNINLINFIIKRSYTNNSKGISKEYVYTKYRISLPYINNVKYDDLYLSSPSREDLYVFTKKIPIFLRFLKLITSLENRNNDFIEFAKRCENGLTIEKDIYLTKEELLELMFINGYSKKEMNAFDLAFSNNYEFHYPEISVLFQLNEEDVYKFCLKKRSENPEKLFHLKFVKDKNMLSSYGLIFVFLYFGLNNVVLSNAWFLSKTIPFFSVFYMLASYFYKDIWNFLNKEKNLMIEQNLNNKLSAEDIIYNQLKLYSKDTECSSNLINFKEYCNKLIKDYRKAYINEQKKKVQENLEKKLNEIHNTEVNYKNSLQNILLEEIIKKIYHNINTDNNFYNSILNDSINNIRNINENDTLINHVRNELNSIKNLDKQNPLIKNILDQYEIKKEEYLNQYVIQKEEVDKIKSIISKCNMDINKLNKNDYNDLLNLYYRINNRFGFYVNDDELSELIPRDEESKKIIDNMNKTINDTNKLFNEKKLVAFLKAFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVV8</accession>
    <name>A0A1J1GVV8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Formin 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00415000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529375.1">
        <property type="nucleotide sequence ID" value="XM_028672864.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732681"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00415000"/>
    <dbReference type="OMA" id="ILICKCY"/>
    <dbReference type="OrthoDB" id="1668162at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2220">
        <property type="entry name" value="Formin, FH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015425">
        <property type="entry name" value="FH2_Formin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042201">
        <property type="entry name" value="FH2_Formin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051425">
        <property type="entry name" value="Formin_Homology"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45725:SF1">
        <property type="entry name" value="DISHEVELLED ASSOCIATED ACTIVATOR OF MORPHOGENESIS, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45725">
        <property type="entry name" value="FORMIN HOMOLOGY 2 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02181">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00498">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101447">
        <property type="entry name" value="Formin homology 2 domain (FH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51444">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FH2" evidence="3">
        <location>
            <begin position="2144"/>
            <end position="2544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="861"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2094"/>
            <end position="2137"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1509"/>
            <end position="1536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="874"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2094"/>
            <end position="2107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2577" mass="300499" checksum="01AA15029B507F25" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVW8</accession>
    <name>A0A1J1GVW8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00363000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529211.1">
        <property type="nucleotide sequence ID" value="XM_028672683.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVW8"/>
    <dbReference type="GeneID" id="39732160"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00363000"/>
    <dbReference type="OMA" id="CCENVEA"/>
    <dbReference type="OrthoDB" id="386127at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012904642" evidence="1">
        <location>
            <begin position="24"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="237" mass="27587" checksum="4D1BE7D366E5896B" modified="2017-02-15" version="1">MKTILVLFLIQIFLCFYQKNVVSKNIKFNIDGNMYTILYDKKKVKFSDLDLLKIMFHSNHIKHCGNSVIRYILKLSTKNLFQMDFVVKHIDITYNKVLKFDDKYKIIGAITNYGNTSLRVSLFGVGNENKKISLNSFIKNKLSNNLELESQSDKNEENSINEVLDNYDEDNDDPINLSSKEIDQLKEEKNCAVYFIVHYTLVKVDKKGMKKNIKDQFKNENSLIEIEQIENLASALC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW42</accession>
    <name>A0A1J1GW42_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00434200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529564.1">
        <property type="nucleotide sequence ID" value="XM_028673074.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW42"/>
    <dbReference type="GeneID" id="39732874"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00434200"/>
    <dbReference type="OrthoDB" id="429842at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049235">
        <property type="entry name" value="DUF6832"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013584">
        <property type="entry name" value="RAP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20724">
        <property type="entry name" value="DUF6831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20725">
        <property type="entry name" value="DUF6832"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51286">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RAP" evidence="1">
        <location>
            <begin position="379"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="485" mass="58353" checksum="3491B4ECC001C0C4" modified="2017-02-15" version="1">MNLKILKNIKRYDNIFHRKRKYIATESIIKNSYLTKEYYDKSKKKKIDLFDFIPPENFISSYFQKLDKCYSNPRSILRLYKDYIDKEDYPNYNWLVRCFCQLANVFGFNSFWSIKDKEAIHDLKLFKYLIYDLIEKKELIKPRHCPRLLYAMCCLDYRCYFLIPTILEIIEINLEKYRIPTLCMISFCLSYLGLTNKNVQFGSENNLSRSYNLIIKVLNNIYERREEAKSDTTNFCWSLLSYVIVINNMYEFPSKDNSFLPDILTNACKSLTKENISESGWLQYFLYITLYCCDVEKPSNELEIKKSIPFFIQEYLHLKWLDNILITAQNQGSEKMQLEMENIIQKLKLKNFFINLSVGRKIDEQHCFFTSHFYKPFNLCIEYDYFHPIGFNRPLVSGIISLKNRIFKKLNFNVVNIHKCFWDLLSDEEKESQLIKIIEAFQTKQNTETLKEKEYYGEKKFDSNMLHLKHKRIKFHSWPPENITV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW43</accession>
    <name>A0A1J1GW43_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00426600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529490.1">
        <property type="nucleotide sequence ID" value="XM_028672993.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW43"/>
    <dbReference type="GeneID" id="39732798"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00426600"/>
    <dbReference type="OMA" id="NEPKICE"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="69" mass="7633" checksum="6CBD58DC5E434E22" modified="2017-02-15" version="1">MGCTQSKVNEPKICEPNDVEKKNEENNVNEKKNETTQPSPVTRKELDVKPPPVKAIPKIVPKAIPKKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWT6</accession>
    <name>A0A1J1GWT6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ADF-H domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00459900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529822.1">
        <property type="nucleotide sequence ID" value="XM_028673362.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWT6"/>
    <dbReference type="GeneID" id="39733132"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00459900"/>
    <dbReference type="OMA" id="FYLCHSD"/>
    <dbReference type="OrthoDB" id="371415at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="567"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="568"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="601"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="613" mass="72542" checksum="B8084FCE3E7B553D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWU9</accession>
    <name>A0A1J1GWU9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00449700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000074">
        <property type="protein sequence ID" value="CRG96916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529719.1">
        <property type="nucleotide sequence ID" value="XM_028673247.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWU9"/>
    <dbReference type="GeneID" id="39733030"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00449700"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006496">
        <property type="entry name" value="CHP01606_Plasmodium_spp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09688">
        <property type="entry name" value="Wx5_PLAF3D7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="218" mass="26329" checksum="2B5FAB12491DE118" modified="2017-02-15" version="1" fragment="single">AYTEGCTKECSLDYEKNKWENLLLQQNPYDRWQKVTNPKLFEQFKKETDGMDPKWIDEKWNNEWNNISANKVNELSSIFDRSDISEEEKGKLIFSIMKELSSLYLKFIDECKKEMRDNKSESESKIEMRENKTESECMREMRDNKTEIKSMKDMIDNKTESESMKKMIDNKTESESKSEKEMREHKAESKYKNYYGKNKKKKKKSNILKFLFCRFDNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWV0</accession>
    <name>A0A1J1GWV0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Dihydrouridine synthase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00431600</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529539.1">
        <property type="nucleotide sequence ID" value="XM_028673047.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWV0"/>
    <dbReference type="GeneID" id="39732848"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00431600"/>
    <dbReference type="OMA" id="ACMENTT"/>
    <dbReference type="OrthoDB" id="10262250at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017150">
        <property type="term" value="F:tRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004653">
        <property type="entry name" value="DusA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008774">
        <property type="entry name" value="PRK11815.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42907">
        <property type="entry name" value="FMN-LINKED OXIDOREDUCTASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42907:SF1">
        <property type="entry name" value="FMN-LINKED OXIDOREDUCTASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0288">FMN</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2" id="KW-0820">tRNA-binding</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012000756" evidence="9">
        <location>
            <begin position="22"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="DUS-like FMN-binding" evidence="10">
        <location>
            <begin position="121"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG96735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="490" mass="56632" checksum="F9EF1E42A311FD21" modified="2017-02-15" version="1">MQVKLIGFILCIYFLLLKNHGKTKLKRKTYTLVRVYIEKVKLYKKKKKLWLNISKKYIYCFNKVTDFTKIKNKNNMLTLKENNTGEMLSSCENIFKFENISTYLNSSYWKNKNEVIPFIQVAPMINVTNRHFRALVRIFTKKAQLWTEMIVDNTLLYNLNNLEEYLGFNDNEHPIVCQLGGCDITSMSEAAILVEQAGYDEININVGCPSTKVANKGAFGASLMKKPEHVRNIVYEIKKKVQIPVTVKLRTGVDDYDSFSFLKSFIETVSSAGCNHFIVHARKAWLKGLDPKKNRKIPPLEYKKVYDLCKLYPNLKFTLNGGVKTIEEATALLNGYMPQNNDLNQNNYVFVENYNINPLNGVMIGRACMENTTILYQTDKLIYNEKVPDTAYSRRTALNAYKSYLEENSIFYNVASAFELLKPILGILKGMPGHRLFRNKLDVYIRNYASTLQCSEILEKAMIDVDKIAPGCLDLPLNDYKMHQEYLKNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX09</accession>
    <name>A0A1J1GX09_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Vacuolar import/degradation Vid27 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00457900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529802.1">
        <property type="nucleotide sequence ID" value="XM_028673340.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX09"/>
    <dbReference type="GeneID" id="39733112"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00457900"/>
    <dbReference type="OMA" id="DMCQFKY"/>
    <dbReference type="OrthoDB" id="10251113at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="329"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="817" mass="97725" checksum="0EB10A87C5F0848F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX41</accession>
    <name>A0A1J1GX41_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Exportin-2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00445900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529681.1">
        <property type="nucleotide sequence ID" value="XM_028673205.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX41"/>
    <dbReference type="GeneID" id="39732992"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00445900"/>
    <dbReference type="OMA" id="TIKLIHH"/>
    <dbReference type="OrthoDB" id="3268246at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005043">
        <property type="entry name" value="XPO2_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03378">
        <property type="entry name" value="CAS_CSE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exportin-2 C-terminal" evidence="1">
        <location>
            <begin position="861"/>
            <end position="1224"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1266" mass="150593" checksum="1742F64433F97278" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX69</accession>
    <name>A0A1J1GX69_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00281300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528424.1">
        <property type="nucleotide sequence ID" value="XM_028671808.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX69"/>
    <dbReference type="GeneID" id="39731346"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00281300"/>
    <dbReference type="OrthoDB" id="434319at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="785" mass="94727" checksum="312A3957EE4958D3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX96</accession>
    <name>A0A1J1GX96_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fam-i protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00450700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000080">
        <property type="protein sequence ID" value="CRG96926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529729.1">
        <property type="nucleotide sequence ID" value="XM_028673258.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX96"/>
    <dbReference type="GeneID" id="39733040"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00450700"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="111"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="224" mass="26680" checksum="3BB488BD7CC691C8" modified="2017-02-15" version="1">MDVNPSDPININSNKRLNEGDSTAGIAHSAKKNATVTKRKNPLHNCFWKLRHANKKPSKDINLDSATSKNLLDKKSLSIFQLKIYSRKLKAKNEMNVRLQKILDNSNKKVKDDLEKEMQEEKKKMEDGQKKLLKEKKEMEHREKGVLRHKEEWERTLKEKQVIDESMLKVLEGRKKRITKEGEKWKKRMLKEKMELDKKMRKNKEEGEKRMLEIIEKFEKEMLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXK1</accession>
    <name>A0A1J1GXK1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00479400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530018.1">
        <property type="nucleotide sequence ID" value="XM_028673580.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXK1"/>
    <dbReference type="GeneID" id="39733327"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00479400"/>
    <dbReference type="OMA" id="FHEACEN"/>
    <dbReference type="OrthoDB" id="372036at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="657"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="118"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="206"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="503"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="657"/>
            <end position="669"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="793" mass="94680" checksum="FFA2C7B388769051" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXQ1</accession>
    <name>A0A1J1GXQ1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">S-adenosylmethionine decarboxylase/ornithine decarboxylase, putative</fullName>
            <ecNumber evidence="14">4.1.1.17</ecNumber>
            <ecNumber evidence="14">4.1.1.50</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">AdoMetDC/ODC</name>
        <name evidence="14" type="ORF">PGAL8A_00492500</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amine and polyamine biosynthesis; S-adenosylmethioninamine biosynthesis; S-adenosylmethioninamine from S-adenosyl-L-methionine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the Orn/Lys/Arg decarboxylase class-II family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the eukaryotic AdoMetDC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.17" evidence="14"/>
    <dbReference type="EC" id="4.1.1.50" evidence="14"/>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00492500"/>
    <dbReference type="OMA" id="YYEQEYP"/>
    <dbReference type="OrthoDB" id="5034579at2759"/>
    <dbReference type="UniPathway" id="UPA00331">
        <property type="reaction ID" value="UER00451"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004014">
        <property type="term" value="F:adenosylmethionine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004586">
        <property type="term" value="F:ornithine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033387">
        <property type="term" value="P:putrescine biosynthetic process from arginine, via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.10:FF:000008">
        <property type="entry name" value="Ornithine decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.37.10:FF:000018">
        <property type="entry name" value="S-adenosylmethionine decarboxylase/ornithine decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="entry name" value="Alanine racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="entry name" value="Lyase, Ornithine Decarboxylase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.90.10">
        <property type="entry name" value="S-adenosylmethionine decarboxylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048283">
        <property type="entry name" value="AdoMetDC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022643">
        <property type="entry name" value="De-COase2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000183">
        <property type="entry name" value="Orn/DAP/Arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002433">
        <property type="entry name" value="Orn_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016067">
        <property type="entry name" value="S-AdoMet_deCO2ase_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11482">
        <property type="entry name" value="ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11482:SF6">
        <property type="entry name" value="ORNITHINE DECARBOXYLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00278">
        <property type="entry name" value="Orn_DAP_Arg_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01536">
        <property type="entry name" value="SAM_decarbox"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01179">
        <property type="entry name" value="ODADCRBXLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01182">
        <property type="entry name" value="ORNDCRBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="Alanine racemase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="PLP-binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56276">
        <property type="entry name" value="S-adenosylmethionine decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="5 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0745">Spermidine biosynthesis</keyword>
    <feature type="domain" description="Orn/DAP/Arg decarboxylase 2 N-terminal" evidence="13">
        <location>
            <begin position="857"/>
            <end position="1133"/>
        </location>
    </feature>
    <feature type="domain" description="Orn/DAP/Arg decarboxylase 2 C-terminal" evidence="12">
        <location>
            <begin position="1217"/>
            <end position="1305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="777"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="784"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9">
        <location>
            <position position="1278"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="9">
        <location>
            <position position="880"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR600183-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG97346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1336" mass="158740" checksum="5B860200B10B3F90" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXY3</accession>
    <name>A0A1J1GXY3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">SNARE protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00499200</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endomembrane system</location>
            <topology evidence="7">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the synaptobrevin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530221.1">
        <property type="nucleotide sequence ID" value="XM_028673805.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXY3"/>
    <dbReference type="GeneID" id="39733525"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00499200"/>
    <dbReference type="OMA" id="RLNFFMW"/>
    <dbReference type="OrthoDB" id="248747at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14824">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15843">
        <property type="entry name" value="R-SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.50:FF:000015">
        <property type="entry name" value="Synaptobrevin 2 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.50">
        <property type="entry name" value="Longin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010908">
        <property type="entry name" value="Longin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001388">
        <property type="entry name" value="Synaptobrevin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051097">
        <property type="entry name" value="Synaptobrevin-like_transport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042855">
        <property type="entry name" value="V_SNARE_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21136">
        <property type="entry name" value="SNARE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21136:SF168">
        <property type="entry name" value="VESICLE-ASSOCIATED MEMBRANE PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13774">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00957">
        <property type="entry name" value="Synaptobrevin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00219">
        <property type="entry name" value="SYNAPTOBREVN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01270">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50859">
        <property type="entry name" value="LONGIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00417">
        <property type="entry name" value="SYNAPTOBREVIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50892">
        <property type="entry name" value="V_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Longin" evidence="10">
        <location>
            <begin position="7"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="V-SNARE coiled-coil homology" evidence="11">
        <location>
            <begin position="123"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00046280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG97420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="208" mass="24795" checksum="AEAC7E033C682FD6" modified="2017-02-15" version="1">MSIIYGLVARDKTVLAEYTEFGGNFSNITRLLLEIIPPHSSRKSYIYDDYVFHQLMKNGVTFMTMTDKELGFLTPYAFLEEISKIFFKKFKNTSDLITLSLDEQFKPVLKENMRIFNEYESNDVHNIKNQISNIQNIIIENIEKILERREKIDILVNKSEKLNQENISFRRQAMNLNFYMWLENNKLCVYLISSIVIFIFFIWSFYNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXZ1</accession>
    <name>A0A1J1GXZ1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">rRNA-processing protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00470900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529931.1">
        <property type="nucleotide sequence ID" value="XM_028673483.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXZ1"/>
    <dbReference type="GeneID" id="39733242"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00470900"/>
    <dbReference type="OrthoDB" id="427886at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014810">
        <property type="entry name" value="Fcf2_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08698">
        <property type="entry name" value="Fcf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fcf2 pre-rRNA processing C-terminal" evidence="1">
        <location>
            <begin position="39"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="171" mass="20429" checksum="CBEB37DACE19244D" modified="2017-02-15" version="1">MTQLDKKRINILEAVTPEPLSVLDYVNDIIENKKKEKEKKKNYLDEWGNMKKNEKTDELKLQWKLLQHENMYTVNEYHKIKKDEKMPDFFQVATLVNSNDKIKVGEGKESQSLHTSNRRKKRCLSALNLLEKDKNMKKWCIKKYTKIQTEKNIGGKSFVKKQRKQLLKMKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY07</accession>
    <name>A0A1J1GY07_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Membrane integral peptidase, M50 family, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PGAL8A_00501700</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M50B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530245.1">
        <property type="nucleotide sequence ID" value="XM_028673831.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY07"/>
    <dbReference type="GeneID" id="39733550"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00501700"/>
    <dbReference type="OMA" id="YGDITMV"/>
    <dbReference type="OrthoDB" id="371073at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06158">
        <property type="entry name" value="S2P-M50_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052348">
        <property type="entry name" value="Metallopeptidase_M50B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044537">
        <property type="entry name" value="Rip2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35864">
        <property type="entry name" value="ZINC METALLOPROTEASE MJ0611-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35864:SF1">
        <property type="entry name" value="ZINC METALLOPROTEASE YWHC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="95"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="180"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="218"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG97444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="330" mass="39024" checksum="974D6DCA6A4155F5" modified="2017-02-15" version="1">MGSKNRMLFYSNILLPHRKLEKNFLSSYKDRNYEFKKYQDFISYILSLLPLLIISVIHILIKINSYTIGNLFLIISYLFSFFFFILYYYNSHFIFVAFVYFSFVISLCLHEFAHAYVAFKCGDITMIYKGYLYLDILNYLDIFHTLIIPSVTLFITGFALPGNLYWLQLHFIKSRFHLSLIFLSGPLLDIIFIMYIIFFYNLLTYFKNKKIVNVQPHSILFISLATSASFLVDSFLLNMFPIIGFDGWGIIEPYLPYCINSIINEEIVYTYLSYICPLCVFIYFNFIETKYLFFTKVVNFILEKALGIKISHVTKGVNSFPTLYSYLRKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY08</accession>
    <name>A0A1J1GY08_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MSP3-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00494700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530170.1">
        <property type="nucleotide sequence ID" value="XM_028673748.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY08"/>
    <dbReference type="GeneID" id="39733480"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00494700"/>
    <dbReference type="OMA" id="TDCEQAN"/>
    <dbReference type="OrthoDB" id="392935at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010784">
        <property type="entry name" value="Merozoite_SPAM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07133">
        <property type="entry name" value="Merozoite_SPAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="436"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="506"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="542"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="632" mass="70121" checksum="899A456DC7FCE1D4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY38</accession>
    <name>A0A1J1GY38_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Plasmodium RESA N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00475500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529979.1">
        <property type="nucleotide sequence ID" value="XM_028673537.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY38"/>
    <dbReference type="GeneID" id="39733288"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00475500"/>
    <dbReference type="OMA" id="MINATIQ"/>
    <dbReference type="OrthoDB" id="10477315at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="231" mass="28170" checksum="FB5E55BE9442776D" modified="2017-02-15" version="1">MNYRNHLILRFSFIYFYIAFYFLLQCTLKIKSKETLNLQFNKNHVRNLSEHNVENTYKKQETLNNLTGEVLENNCYEATRLEDSEEKIDLDYMRSLWKDMYNEQTLKNDMLNSLIENWDNMCLIHGMDKNSTIEVCKNTRLGCWNRRDAIQKKVNDIKYYNEFKELEEGCTKEQFLHFLDKTKEEMEVRREKLLITWKECLDNSMKMWEMYVKKYSEKKDGEPTEDIKKDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY66</accession>
    <name>A0A1J1GY66_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome c2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00507900</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome c family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530307.1">
        <property type="nucleotide sequence ID" value="XM_028673901.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY66"/>
    <dbReference type="GeneID" id="39733612"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00507900"/>
    <dbReference type="OMA" id="NIGMNFK"/>
    <dbReference type="OrthoDB" id="449280at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="entry name" value="Cytochrome c-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002327">
        <property type="entry name" value="Cyt_c_1A/1B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11961">
        <property type="entry name" value="CYTOCHROME C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="Cytochrome c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4 8" id="KW-0349">Heme</keyword>
    <keyword evidence="7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cytochrome c" evidence="10">
        <location>
            <begin position="25"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG97506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="154" mass="17639" checksum="FBE4415308A114F9" modified="2017-02-15" version="1">MKFNNNKKNDILEDELSDNFVLPEGDKVKGEKLFKKHCKQCHSVAPDNSQTNSGFTSWGPSLFNVYNRTAGMSMGNSPFQVSPDMYSSGIIWNDVNLLKYMKNPKQFVESNIGMNFKGISNFQDRVDIVHYLKTLTYDDPHGREIAEKYSKKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY76</accession>
    <name>A0A1J1GY76_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Haloacid dehalogenase-like hydrolase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00345000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529037.1">
        <property type="nucleotide sequence ID" value="XM_028672490.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY76"/>
    <dbReference type="GeneID" id="39731980"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00345000"/>
    <dbReference type="OMA" id="IRSMDYN"/>
    <dbReference type="OrthoDB" id="444127at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051540">
        <property type="entry name" value="S-2-haloacid_dehalogenase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43316:SF8">
        <property type="entry name" value="HAD FAMILY HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43316">
        <property type="entry name" value="HYDROLASE, HALOACID DELAHOGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="304" mass="36232" checksum="937FE472CBEB965E" modified="2017-02-15" version="1">MKKEKNCYYITPKGRQKCFKNIKLITFDLDHTIWNIEALLNYADNECYKYMRKNYKRLYDYLLKEYELSITKLVKQLLEKNHDFTKDGVQILTRIRIDALKYLAKQTNYDEIKFASEIQQLWNKKKNDVHLFISPGTLEYLRELKNRGYILGAITNGDSDVNGIKFLNEIFSFVIRSMDYNCAKPSIEIFNVAENLLKERNIKFDVEEWLHVGDDVCTDVMGAKNKNINCAWITTFRDGREVSENEWYSYLKLKLEKNNESTLTEYDPYADGLFSRFKKKDIILPYDYIDIEIRHCRDLDKILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYR9</accession>
    <name>A0A1J1GYR9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00517300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530401.1">
        <property type="nucleotide sequence ID" value="XM_028674005.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYR9"/>
    <dbReference type="GeneID" id="39733706"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00517300"/>
    <dbReference type="OrthoDB" id="371315at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="619" mass="72991" checksum="F8622A03152B8639" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ95</accession>
    <name>A0A1J1GZ95_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00355700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529144.1">
        <property type="nucleotide sequence ID" value="XM_028672608.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ95"/>
    <dbReference type="GeneID" id="39732087"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00355700"/>
    <dbReference type="OMA" id="FGYQFDY"/>
    <dbReference type="OrthoDB" id="343184at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="512"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="512"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="525"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="628" mass="74226" checksum="504FF94B9EA030F4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZE3</accession>
    <name>A0A1J1GZE3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TATA-box-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TBP</name>
        <name evidence="4" type="ORF">PGAL8A_00027300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530638.1">
        <property type="nucleotide sequence ID" value="XM_028674268.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZE3"/>
    <dbReference type="GeneID" id="39728796"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00027300"/>
    <dbReference type="OMA" id="FHFKIAE"/>
    <dbReference type="OrthoDB" id="2127950at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.310.10:FF:000015">
        <property type="entry name" value="Transcription initiation factor TFiid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="entry name" value="TATA-Binding Protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000814">
        <property type="entry name" value="TBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030491">
        <property type="entry name" value="TBP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10126">
        <property type="entry name" value="TATA-BOX BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00352">
        <property type="entry name" value="TBP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00686">
        <property type="entry name" value="TIFACTORIID"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55945">
        <property type="entry name" value="TATA-box binding protein-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00351">
        <property type="entry name" value="TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="246" mass="28036" checksum="4F90C998DF1D1457" modified="2017-02-15" version="1">MSERNDEENNLNKLSLLSDDQENDINNESVNFSTENILENYDEININSDGKGMSDSIKNKLVHKNVSLKIHNIISSANLCLEIDLRLIAVSIRNAEYNPSKINTLIIRLNKPKCTALIFKNGRIMLTGTKTKNDSIYGCKKIGKIIKIITNKSVKFQNFKIENIIASANCNMPIRLEMLAHDHKEYCNYEPELFAGLVYRYKPTSKLKSVILIFVSGKIIITGCKSIQKLNTVFQDIYNVLIQYKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZK0</accession>
    <name>A0A1J1GZK0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">1-phosphatidylinositol 4-kinase</fullName>
            <ecNumber evidence="2">2.7.1.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PI4K</name>
        <name evidence="9" type="ORF">PGAL8A_00030900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19877"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57880"/>
            <dbReference type="ChEBI" id="CHEBI:58178"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.67"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.67" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530673.1">
        <property type="nucleotide sequence ID" value="XM_028674306.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728832"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00030900"/>
    <dbReference type="OMA" id="YNCIVND"/>
    <dbReference type="OrthoDB" id="10264149at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004430">
        <property type="term" value="F:1-phosphatidylinositol 4-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05168">
        <property type="entry name" value="PI4Kc_III_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1070.11:FF:000027">
        <property type="entry name" value="Putative Phosphatidylinositol 4-kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.70">
        <property type="entry name" value="Phosphatidylinositol 3-kinase, accessory domain (PIK)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015433">
        <property type="entry name" value="PI3/4_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001263">
        <property type="entry name" value="PI3K_accessory_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042236">
        <property type="entry name" value="PI3K_accessory_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057754">
        <property type="entry name" value="PI4-kinase_beta/PIK1_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049160">
        <property type="entry name" value="PI4KB-PIK1_PIK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048:SF22">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21245">
        <property type="entry name" value="PI4KB-PIK1_PIK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00915">
        <property type="entry name" value="PI3_4_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51545">
        <property type="entry name" value="PIK_HELICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PIK helical" evidence="8">
        <location>
            <begin position="338"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="7">
        <location>
            <begin position="1202"/>
            <end position="1467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="211"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="614"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1133"/>
            <end position="1164"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="316"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="223"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="624"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="643"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="662"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1142"/>
            <end position="1153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1154"/>
            <end position="1164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG97874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1482" mass="175273" checksum="D765AB5BD25809B9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZL1</accession>
    <name>A0A1J1GZL1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nucleosome assembly protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00431800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the nucleosome assembly protein (NAP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529541.1">
        <property type="nucleotide sequence ID" value="XM_028673049.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZL1"/>
    <dbReference type="GeneID" id="39732850"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00431800"/>
    <dbReference type="OMA" id="WPVALMN"/>
    <dbReference type="OrthoDB" id="19419at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051262">
        <property type="term" value="P:protein tetramerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.90">
        <property type="entry name" value="Nucleosome assembly protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.170.10">
        <property type="entry name" value="p53-like tetramerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037231">
        <property type="entry name" value="NAP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002164">
        <property type="entry name" value="NAP_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036674">
        <property type="entry name" value="p53_tetramer_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11875">
        <property type="entry name" value="TESTIS-SPECIFIC Y-ENCODED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00956">
        <property type="entry name" value="NAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143113">
        <property type="entry name" value="NAP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="227"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="277" mass="32835" checksum="F112B40F00D467C7" modified="2017-02-15" version="1">MKRDRSENSAENTTDPKHTKIDNDDPLVPYMKDFEDIQKDIEQLDIKCAHEQMNIQKQYDEKKKPLFEKREEIIGKVPGFWANTLRKHPALSDIVPEDIEILKHLIKLDLKDNMDNNGSYKITFIFGEKAKEFMEPLTLVKHVTFDNNQEKVVECTRIKWKEGKNPIAAVTNNRSDLDNEIPKWSIFEWFTTEELQDKPDLGELIRREIWHNPLSYYLGIDEFEDFEEDFDEEFDDDDEDEDEDDDDDDDEKDDDDEDKDDDRDGDEDDGKDDDNED</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZN3</accession>
    <name>A0A1J1GZN3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-directed RNA polymerase I, putative</fullName>
            <ecNumber evidence="5">2.7.7.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00370800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529288.1">
        <property type="nucleotide sequence ID" value="XM_028672769.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZN3"/>
    <dbReference type="GeneID" id="39732238"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00370800"/>
    <dbReference type="OMA" id="KKKCRAF"/>
    <dbReference type="OrthoDB" id="270173at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07032">
        <property type="entry name" value="RNAP_I_II_AC40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.12">
        <property type="entry name" value="DNA-directed RNA polymerase, insert domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="entry name" value="RNA polymerase, RBP11-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00320">
        <property type="entry name" value="RNApol_arch_Rpo3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011262">
        <property type="entry name" value="DNA-dir_RNA_pol_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011263">
        <property type="entry name" value="DNA-dir_RNA_pol_RpoA/D/Rpb3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022842">
        <property type="entry name" value="RNAP_Rpo3/Rpb3/RPAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033901">
        <property type="entry name" value="RNAPI/III_AC40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036643">
        <property type="entry name" value="RNApol_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050518">
        <property type="entry name" value="Rpo3/RPB3_RNA_Pol_subunit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001988">
        <property type="entry name" value="PRK00783.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11800">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11800:SF13">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01000">
        <property type="entry name" value="RNA_pol_A_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01193">
        <property type="entry name" value="RNA_pol_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00662">
        <property type="entry name" value="RPOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56553">
        <property type="entry name" value="Insert subdomain of RNA polymerase alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="RBP11-like subunits of RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase RpoA/D/Rpb3-type" evidence="4">
        <location>
            <begin position="59"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="331" mass="38381" checksum="964A1FF059B85AB1" modified="2017-02-15" version="1">MESVKFTDNFIKLGEEGPRNATTTNFYGSYFLSEKENYFDINEFEKNLEMNILKNEHNLLILEVKNLNVSIANALRRIMISEVPTIAIEKVNIFQNTGIIADEILCHRLGLIPFKFDADLINYKEEYEKYNHLNCFCFKLHVKYKKIGNENSLSVYSKDLKWFPINEQQKIKFEKNHPKVVDDNILITKLSSGQEIELICFLEKGIGKTHAKWSPVCTSVYKMYPSFTFNTSENLTKEEKYDLVNICPKNVFDIEESGNLVVKDPLNCSSCRVCIEKYPKKVSFHKVKNHFIFTIESTGCFSSADIFKKALLILKQKVLNIKEALEEETNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZX9</accession>
    <name>A0A1J1GZX9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">tRNA m5C-methyltransferase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00044300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530809.1">
        <property type="nucleotide sequence ID" value="XM_028674459.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZX9"/>
    <dbReference type="GeneID" id="39728968"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00044300"/>
    <dbReference type="OMA" id="ANFKRCC"/>
    <dbReference type="OrthoDB" id="6093671at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001510">
        <property type="term" value="P:RNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049560">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22808">
        <property type="entry name" value="NCL1 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22808:SF1">
        <property type="entry name" value="RNA CYTOSINE-C(5)-METHYLTRANSFERASE NSUN2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM-dependent MTase RsmB/NOP-type" evidence="6">
        <location>
            <begin position="188"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="416"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="363"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG98012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1047" mass="124569" checksum="F772B6905A69C26E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H005</accession>
    <name>A0A1J1H005_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">tRNA N6-adenosine threonylcarbamoyltransferase, putative</fullName>
            <ecNumber evidence="5">2.3.1.234</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">KAE1</name>
        <name evidence="5" type="ORF">PGAL8A_00059500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.234" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530957.1">
        <property type="nucleotide sequence ID" value="XM_028674623.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H005"/>
    <dbReference type="GeneID" id="39729120"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00059500"/>
    <dbReference type="OrthoDB" id="10259622at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061711">
        <property type="term" value="F:tRNA N(6)-L-threonylcarbamoyladenine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF6">
        <property type="entry name" value="TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="Gcp-like" evidence="4">
        <location>
            <begin position="332"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="290"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="511"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG98160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="693" mass="81802" checksum="39F289BB94A232FF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H031</accession>
    <name>A0A1J1H031_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Apicoplast integral membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00420800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529432.1">
        <property type="nucleotide sequence ID" value="XM_028672928.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H031"/>
    <dbReference type="GeneID" id="39732740"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00420800"/>
    <dbReference type="OMA" id="HTGFIPM"/>
    <dbReference type="OrthoDB" id="372472at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013085613" description="Apicoplast integral membrane protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="278"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="312"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="351"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="383"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="420"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="452"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="490"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="513" mass="61864" checksum="83A025C14BA77612" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H050</accession>
    <name>A0A1J1H050_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00050300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530865.1">
        <property type="nucleotide sequence ID" value="XM_028674520.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H050"/>
    <dbReference type="GeneID" id="39729028"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00050300"/>
    <dbReference type="OMA" id="AMYFLQL"/>
    <dbReference type="OrthoDB" id="437309at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="370"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="436" mass="52212" checksum="B2CBCF73A54A3939" modified="2017-02-15" version="1">MNYIHLKNLQSNCWRNKRCNYFICLHNLYKIETIFNVKKNKFSILKNSKNLDEYINYNNKKYIFAKYRFFSNSKKENVVNKNLENENSPVNYNNTVTEENKCKLIEEKDIDENNINDITKKKKKFSKLKIFAYSFNIIFFSYVIYKVYKNDMNLSKAEESIIRDFVKLFYSYEEKNSVKNSQFLTCLNEDLSRQIAMYFIQLDTDKSSGFLINDAVNFLSELNINEDNEIIKKFIKKGNGKSIELKKLSGCSLQEFAELIESLILVNKTKNETYLSKRLSSLENEKTYYIDVLQYYLDSIVNFVKTSKIFLYYQSKKKKTNEDIKQIDNLEKLILDKLIQYNEKYVDKKNLSLDYLLSKEELNYLKNNNLSKKKEEKEILLVEKKILEDKIQILNNLQLKKNLTEAEIKRLEDLKVKLKNLKKTIRKEELKKYFFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0N0</accession>
    <name>A0A1J1H0N0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcription initiation factor TFIID subunit 7, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">TAF7</name>
        <name evidence="7" type="ORF">PGAL8A_00441800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529640.1">
        <property type="nucleotide sequence ID" value="XM_028673159.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0N0"/>
    <dbReference type="GeneID" id="39732951"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00441800"/>
    <dbReference type="OMA" id="AKLYKYH"/>
    <dbReference type="OrthoDB" id="153872at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08047">
        <property type="entry name" value="TAF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037817">
        <property type="entry name" value="TAF7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006751">
        <property type="entry name" value="TAFII55_prot_cons_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12228:SF0">
        <property type="entry name" value="TATA-BOX BINDING PROTEIN ASSOCIATED FACTOR 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12228">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID 55 KD SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04658">
        <property type="entry name" value="TAFII55_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01370">
        <property type="entry name" value="TAFII55_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TAFII55 protein conserved region" evidence="6">
        <location>
            <begin position="104"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="345" mass="41015" checksum="C3DB99D42054597E" modified="2017-02-15" version="1">MEKKNPNFKKISININTKKDENDLNEQNIESNESKVKSNSKEIIQTLNTIENIRKGTFEYEDLQEIYFMNDLDLLNIINDAKCREDKMKNKDNINNVYMLDSDVDKVCIIRFPPSVSKKIKKHLLKKNLELEIEPTNLLNSRFFIINFKNINKKYYGILVELATHIEIHKTLDGINLYKTSDVSQMIYVYENNKNSKKLLRKFINNNFQLNCGISNKTNNFNFQNYAKLYKYHDIYFAQKLIYEYLNSDFYDYYDIYVKTYNEMLNHISNEKENNKQNEIVDELTDLSEILSSLDNTYNLMNQIEKENGDINFEALLNYEIENENYESDVSDLLLGGNHYLKKKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0R3</accession>
    <name>A0A1J1H0R3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">DNA mismatch repair protein MSH2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00046800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530834.1">
        <property type="nucleotide sequence ID" value="XM_028674486.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0R3"/>
    <dbReference type="GeneID" id="39728993"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00046800"/>
    <dbReference type="OMA" id="LVRFPQK"/>
    <dbReference type="OrthoDB" id="295033at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032301">
        <property type="term" value="C:MutSalpha complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043570">
        <property type="term" value="P:maintenance of DNA repeat elements"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006312">
        <property type="term" value="P:mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03285">
        <property type="entry name" value="ABC_MSH2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001115">
        <property type="entry name" value="DNA mismatch repair protein MSH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="entry name" value="MutS, connector domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011184">
        <property type="entry name" value="DNA_mismatch_repair_Msh2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032642">
        <property type="entry name" value="Msh2_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF35">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MSH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005813">
        <property type="entry name" value="MSH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="9">
        <location>
            <begin position="636"/>
            <end position="652"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG98037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="809" mass="94217" checksum="E49DE229D80084A1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0U8</accession>
    <name>A0A1J1H0U8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">U2 small nuclear ribonucleoprotein B'', putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00448200</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRM U1 A/B'' family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529704.1">
        <property type="nucleotide sequence ID" value="XM_028673230.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0U8"/>
    <dbReference type="GeneID" id="39733015"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00448200"/>
    <dbReference type="OMA" id="VRMIPTK"/>
    <dbReference type="OrthoDB" id="277802at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030532">
        <property type="term" value="C:small nuclear ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12246">
        <property type="entry name" value="RRM1_U1A_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12247">
        <property type="entry name" value="RRM2_U1A_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000039">
        <property type="entry name" value="U1 small nuclear ribonucleoprotein A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000029">
        <property type="entry name" value="U2 small nuclear ribonucleoprotein B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10501">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="9 12" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="RRM" evidence="11">
        <location>
            <begin position="10"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="11">
        <location>
            <begin position="120"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG96901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="192" mass="22231" checksum="2C7059C75AAD09E4" modified="2017-02-15" version="1">MENFDIPPNQTLYVNNLEDKINVNDLKFLLYEFFCPYGSIIDIVLKKSNRSRGQAFIVFNNIASSTLACKNLKGKLFLNKNININYAKTKSRIIEKLEGTYKPTKTCKSLNNYENKTNLYTLFVQNLPNEINKNALEILFNQYPGYFEARYIPGRNVAFIDFTSYQNGEIAMNGLQNFKITPQHPIKISWSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0Z3</accession>
    <name>A0A1J1H0Z3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ATP-dependent protease subunit ClpQ, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ClpQ</name>
        <name evidence="5" type="ORF">PGAL8A_00452100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase T1B family. HslV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529744.1">
        <property type="nucleotide sequence ID" value="XM_028673274.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0Z3"/>
    <dbReference type="GeneID" id="39733054"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00452100"/>
    <dbReference type="OMA" id="WRTDKML"/>
    <dbReference type="OrthoDB" id="276825at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009376">
        <property type="term" value="C:HslUV protease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005839">
        <property type="term" value="C:proteasome core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01913">
        <property type="entry name" value="protease_HslV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000057">
        <property type="entry name" value="ATP-dependent protease subunit ClpQ, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022281">
        <property type="entry name" value="ATP-dep_Prtase_HsIV_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03692">
        <property type="entry name" value="ATP_dep_HslV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003964">
        <property type="entry name" value="PRK05456.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF7">
        <property type="entry name" value="ATP-DEPENDENT PROTEASE SUBUNIT HSLV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0888">Threonine protease</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="207" mass="23147" checksum="1A4190480D73D3BB" modified="2017-02-15" version="1">MYIRYFSNLINTHKPITKTILRNYFSDNRKLIIPRYGTTILCVRKNNEVCLIGDGMVSQGTMIVKGNAKKIRRLKDNILMGFAGATADCFTLLDKFETKIDEYPNQLLRSCVELAKLWRTDRYLRHLEAVLIVADKDILLEVTGNGDVLEPSGNVLGTGSGGPYAIAAARALYDIENLSAKDIAYKAMNIAADMCCHTNNNFICETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H106</accession>
    <name>A0A1J1H106_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">phenylalanine--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Phenylalanyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PGAL8A_00453700</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>tRNA(Phe) + L-phenylalanine + ATP = L-phenylalanyl-tRNA(Phe) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529760.1">
        <property type="nucleotide sequence ID" value="XM_028673292.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H106"/>
    <dbReference type="GeneID" id="39733070"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00453700"/>
    <dbReference type="OMA" id="IKNHPIH"/>
    <dbReference type="OrthoDB" id="4457at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.380">
        <property type="entry name" value="Ferrodoxin-fold anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005121">
        <property type="entry name" value="Fdx_antiC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036690">
        <property type="entry name" value="Fdx_antiC-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002319">
        <property type="entry name" value="Phenylalanyl-tRNA_Synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538:SF41">
        <property type="entry name" value="PHENYLALANINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538">
        <property type="entry name" value="PHENYLALANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01409">
        <property type="entry name" value="tRNA-synt_2d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00896">
        <property type="entry name" value="FDX-ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54991">
        <property type="entry name" value="Anticodon-binding domain of PheRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011955606" description="phenylalanine--tRNA ligase" evidence="13">
        <location>
            <begin position="20"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="14">
        <location>
            <begin position="228"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG96957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="550" mass="66331" checksum="33324FF151853C84" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1D1</accession>
    <name>A0A1J1H1D1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00469800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529920.1">
        <property type="nucleotide sequence ID" value="XM_028673471.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1D1"/>
    <dbReference type="GeneID" id="39733231"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00469800"/>
    <dbReference type="OMA" id="PLHKSQL"/>
    <dbReference type="OrthoDB" id="371266at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="363"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="404"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="433"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="477"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="604" mass="73268" checksum="01E560C40B2C8B92" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1E1</accession>
    <name>A0A1J1H1E1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">phosphatidylinositol N-acetylglucosaminyltransferase</fullName>
            <ecNumber evidence="2">2.4.1.198</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">GlcNAc-PI synthesis protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PIGA</name>
        <name evidence="10" type="ORF">PGAL8A_00491800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.198" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530141.1">
        <property type="nucleotide sequence ID" value="XM_028673716.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1E1"/>
    <dbReference type="GeneID" id="39733451"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00491800"/>
    <dbReference type="OMA" id="SDWYFPK"/>
    <dbReference type="OrthoDB" id="734129at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000506">
        <property type="term" value="C:glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017176">
        <property type="term" value="F:phosphatidylinositol N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03796">
        <property type="entry name" value="GT4_PIG-A-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000148">
        <property type="entry name" value="Phosphatidylinositol N-acetylglucosaminyltransferase subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039507">
        <property type="entry name" value="PIG-A/GPI3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013234">
        <property type="entry name" value="PIGA_GPI_anchor_biosynthesis"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45871">
        <property type="entry name" value="N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45871:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08288">
        <property type="entry name" value="PIGA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="409"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="PIGA GPI anchor biosynthesis" evidence="9">
        <location>
            <begin position="66"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="8">
        <location>
            <begin position="224"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG97339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="456" mass="52546" checksum="6FF416D708E71D9E" modified="2017-02-15" version="1">MIYKNKEINKTKNKNEQELIYKKERKCCICMVSDFFYPNLGGIEMHIFELSKQLIRKGFKVIIVTHCYNNRNGIRWMGNGIKVYYLPIYPFLDVVTVPNIIGSLPLCRNILFREKVDIVHGHQATSTLAHEFILHAKSLGIKTIYTDHSLYSFSDKGCIHVNKLLKYCINDVDHSICVSHTNRENLVLRTEINPYNTSVIGNALDTKKFVPCINKRPEFPRINIIVISRLTYRKGIDLIVKVIPPVCKKYPFINFIIGGDGPKRILLEEMREKYHLHNSVILLGKIKHEEVKNVLQTGHIFLNTSLTEAFCIAIIEAASCGLLVISTDVGGISEVLPQDMMILSKPNHIDLCKAVDNALEIVKNVDSNSFHERLTKMYSWEKVAEKTEKVYMKVLSHPNPTLLSRIQKIYGISRVFSKIYIFIIIVSYLYCQILEWINPKEDIEEAVSFPHFIEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1U8</accession>
    <name>A0A1J1H1U8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Inner membrane complex protein 1m, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">IMC1m</name>
        <name evidence="2" type="ORF">PGAL8A_00488100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530104.1">
        <property type="nucleotide sequence ID" value="XM_028673675.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1U8"/>
    <dbReference type="GeneID" id="39733414"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00488100"/>
    <dbReference type="OMA" id="FEGYNDN"/>
    <dbReference type="OrthoDB" id="369807at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="337" mass="38856" checksum="FC579EA7182C0460" modified="2017-02-15" version="1">MCDNICKDEKKYILGPAPPLMPQLIEDSPSTTVEVDVPIYESLVKPVIKNIIQETTINVPKIEYREKVVEVPRIEYRTYPVVKDIETPIYQDKYKYKNVEVPQKKLRVKPVYKVVDVPQIEYVDKYVKKKYKRFKYVPKEVQVPFRPRREIHNEVPIPRYIPQNINTIIQPDMFSAPYTGELPLFEGHNDNFLNMLNPFTVYGREKKNKCFLSCLCNGNDEATYEMNPLLVSSPPYNNQLCDISNNYELYPGSCDPLGYSYPFIIDNEENNFCNKIIEATSSIIAATGIAVILAGKLTLDGISLFLKSKNEENKKDTENILDSKINESSSAKKKEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1Z5</accession>
    <name>A0A1J1H1Z5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Haloacid dehalogenase-like hydrolase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">HAD1</name>
        <name evidence="1" type="ORF">PGAL8A_00492900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530152.1">
        <property type="nucleotide sequence ID" value="XM_028673728.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1Z5"/>
    <dbReference type="GeneID" id="39733462"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00492900"/>
    <dbReference type="OMA" id="QVIFQAM"/>
    <dbReference type="OrthoDB" id="27226at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000150">
        <property type="entry name" value="Cof"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00099">
        <property type="entry name" value="Cof-subfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10000:SF8">
        <property type="entry name" value="HAD SUPERFAMILY HYDROLASE-LIKE, TYPE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10000">
        <property type="entry name" value="PHOSPHOSERINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08282">
        <property type="entry name" value="Hydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01140">
        <property type="entry name" value="C2.B:_Phosphomannomutase_and_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01228">
        <property type="entry name" value="COF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="287" mass="32566" checksum="7BD2801382E20992" modified="2017-02-15" version="1">MYEIRDKTGKIVQRENINEIKIIFTDLDGTLLNSEHKVSDLNLQSLIKARDKGIKIVISTGRTLLSVERIIGKDLKKNNLNLLPGIYLNGSVTFDSSGSLIVDKVIDNNLKMEINDFVRNLNISEYCVWYSSNKTYCFSMNDKIQYHSEIECITPEIIKEQDLKNINVYKVLFCLDKTNLESVLKLSKDKFIKKINVTNTFECFIELFHQDINKLEGIKEICNLYNISLNNALAIGDGENDMEMLNGLPHSVAVSNASDKVKKCAKYIGPSNNENAVAHVLQTFCDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H331</accession>
    <name>A0A1J1H331_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00532000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530543.1">
        <property type="nucleotide sequence ID" value="XM_028674162.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H331"/>
    <dbReference type="GeneID" id="39733853"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00532000"/>
    <dbReference type="OrthoDB" id="392648at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="656"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="657"/>
            <end position="668"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="901" mass="107649" checksum="CDD28F17D52ECA0C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H377</accession>
    <name>A0A1J1H377_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">tRNA pseudouridine synthase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00037800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the tRNA pseudouridine synthase TruA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530740.1">
        <property type="nucleotide sequence ID" value="XM_028674381.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H377"/>
    <dbReference type="GeneID" id="39728902"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00037800"/>
    <dbReference type="OMA" id="LPNDNIC"/>
    <dbReference type="OrthoDB" id="271910at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.660">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00171">
        <property type="entry name" value="TruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001406">
        <property type="entry name" value="PsdUridine_synth_TruA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020097">
        <property type="entry name" value="PsdUridine_synth_TruA_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020095">
        <property type="entry name" value="PsdUridine_synth_TruA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142:SF0">
        <property type="entry name" value="TRNA PSEUDOURIDINE SYNTHASE-LIKE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01416">
        <property type="entry name" value="PseudoU_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Pseudouridine synthase I TruA alpha/beta" evidence="4">
        <location>
            <begin position="401"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="521" mass="61198" checksum="1B039445E6DA8F81" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H400</accession>
    <name>A0A1J1H400_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Coatomer epsilon subunit, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00051700</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasmic vesicle</location>
            <location evidence="2">COPI-coated vesicle membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the COPE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530879.1">
        <property type="nucleotide sequence ID" value="XM_028674537.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H400"/>
    <dbReference type="GeneID" id="39729042"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00051700"/>
    <dbReference type="OMA" id="YIYQIYM"/>
    <dbReference type="OrthoDB" id="310217at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006822">
        <property type="entry name" value="Coatomer_esu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10805">
        <property type="entry name" value="COATOMER SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10805:SF0">
        <property type="entry name" value="COATOMER SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04733">
        <property type="entry name" value="Coatomer_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG98082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="282" mass="33638" checksum="0D6DC266AA2F879F" modified="2017-02-15" version="1">MDGTLQLRDYFYAGFNNYCLNNYKNIEEEEEKKEADEYIYQIYMISNIKKDFILSLKYEKNENLYLLYLYYKYYYLNEKEDVLSELKNLKISSTNGNILKSRILFDNDLLDECFDLLEDGTVEVKAAKIFFLLSINRNDLVKEIINEYLKMNDEIPIIKIALAIYYLYNDNYKESFLIFDDLESLYSSVVNDFSTIILNGKSVSNIISYEFNDAKEYLKNAIKNEINNSDILYNLITCSLYLYELDEAEEYLKKLYDFFPVHDSISVLRKIDYEVDNFVCEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2012-05-16" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>H7CDZ1</accession>
    <name>H7CDZ1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA-directed RNA polymerase subunit</fullName>
            <ecNumber evidence="7">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rpoC</name>
        <name evidence="11" type="ORF">PGAL8A_API04200</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <geneLocation type="apicoplast" evidence="10"/>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2012" name="Mol. Biol. Evol." volume="29" first="2095" last="2099">
            <title>The Plasmodium Apicoplast Genome: Conserved Structure and Close Relationship of P. ovale to Rodent Malaria Parasites.</title>
            <authorList>
                <person name="Arisue N."/>
                <person name="Hashimoto T."/>
                <person name="Mitsui H."/>
                <person name="Palacpac N.M.Q."/>
                <person name="Kaneko A."/>
                <person name="Kawai S."/>
                <person name="Hasegawa M."/>
                <person name="Tanabe K."/>
                <person name="Horii T."/>
            </authorList>
            <dbReference type="PubMed" id="22396524"/>
            <dbReference type="DOI" id="10.1093/molbev/mss082"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">A8</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the RNA polymerase beta' chain family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="7"/>
    <dbReference type="EMBL" id="AB649424">
        <property type="protein sequence ID" value="BAL70761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LN835293">
        <property type="protein sequence ID" value="CRG98252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009325479.1">
        <property type="nucleotide sequence ID" value="NC_031963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="H7CDZ1"/>
    <dbReference type="GeneID" id="30315804"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_API04200"/>
    <dbReference type="OMA" id="WGERTLP"/>
    <dbReference type="OrthoDB" id="35434at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Apicoplast API"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006592">
        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007080">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376:SF54">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04997">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0933">Apicoplast</keyword>
    <keyword evidence="2 7 10" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-0934">Plastid</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase N-terminal" evidence="9">
        <location>
            <begin position="235"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAL70761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG98252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="573" mass="68917" checksum="4336D68A2F0A4F7B" modified="2012-05-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL53</accession>
    <name>A0A1J1GL53_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">40S ribosomal protein S5, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00084800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525966.1">
        <property type="nucleotide sequence ID" value="XM_028670977.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL53"/>
    <dbReference type="GeneID" id="39729372"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00084800"/>
    <dbReference type="OMA" id="QANEWPE"/>
    <dbReference type="OrthoDB" id="10264639at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14867">
        <property type="entry name" value="uS7_Eukaryote"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.455.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="entry name" value="Ribosomal protein S7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_uS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020606">
        <property type="entry name" value="Ribosomal_uS7_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023798">
        <property type="entry name" value="Ribosomal_uS7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_uS7_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005716">
        <property type="entry name" value="Ribosomal_uS7_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003106">
        <property type="entry name" value="PRK04027.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01028">
        <property type="entry name" value="uS7_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11205">
        <property type="entry name" value="RIBOSOMAL PROTEIN S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00177">
        <property type="entry name" value="Ribosomal_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002122">
        <property type="entry name" value="RPS7p_RPS7a_RPS5e_RPS7o"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="Ribosomal protein S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00052">
        <property type="entry name" value="RIBOSOMAL_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS7" evidence="5">
        <location>
            <begin position="37"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="194" mass="21803" checksum="E5B13B2867D480FF" modified="2017-02-15" version="1">METTCDIKLFKKWSYEEVNIADLSLVDCIAVSQKACVYTPHTAGRYQKKRFRKALCPIVERLVNSMMMHGRNNGKKLKAIRIVAYAFEIIHLMTGENPIQVFVNAVQKGGPREDSTRIGSAGVVRRQAVDVSPLRRVNQAIYLICTGARNAAFRNIKSISECLAEEIIHCANESSSSYAIKKKDEIERVAKANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLA3</accession>
    <name>A0A1J1GLA3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tetratricopeptide repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00084100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525959.1">
        <property type="nucleotide sequence ID" value="XM_028670899.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLA3"/>
    <dbReference type="GeneID" id="39729365"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00084100"/>
    <dbReference type="OMA" id="KKNRDMQ"/>
    <dbReference type="OrthoDB" id="199930at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="156"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="205" mass="24730" checksum="51F33435AF6C1A3C" modified="2017-02-15" version="1">MFLSEDLDPEELKNEANLKWKNGEIEDANNLWRQALKECIKYSMRGYPTTKNRDMQISLRLNLSLYHFKKNELSECINQCNIILENLMNLNDVLNYYENNKNIEKEINEINKINEEKKDDTISENKFIKKDTLIKIFLRRANSFLCLQDFDKCRENIELIKRLDNKNVEMIALEKKMKIEEVDYNKKQKELYKKMCNTIKKKEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLT1</accession>
    <name>A0A1J1GLT1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00104300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526159.1">
        <property type="nucleotide sequence ID" value="XM_028673121.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLT1"/>
    <dbReference type="GeneID" id="39729568"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00104300"/>
    <dbReference type="OMA" id="MNQSEMN"/>
    <dbReference type="OrthoDB" id="691673at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="632" mass="76201" checksum="5A75EBE9E76AB3F0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLU3</accession>
    <name>A0A1J1GLU3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00108700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dpy-19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526204.1">
        <property type="nucleotide sequence ID" value="XM_028673621.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLU3"/>
    <dbReference type="GeneID" id="39729613"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00108700"/>
    <dbReference type="OrthoDB" id="537915at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005637">
        <property type="term" value="C:nuclear inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000030">
        <property type="term" value="F:mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018732">
        <property type="entry name" value="Dpy-19/Dpy-19-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31488:SF1">
        <property type="entry name" value="C-MANNOSYLTRANSFERASE DPY19L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31488">
        <property type="entry name" value="DPY-19-LIKE 1, LIKE (H. SAPIENS)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10034">
        <property type="entry name" value="Dpy19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="171"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="266"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="431"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="466"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="493"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="531"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="984" mass="118475" checksum="ABA890ECD9C0FFCE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLV5</accession>
    <name>A0A1J1GLV5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphatase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00110300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526220.1">
        <property type="nucleotide sequence ID" value="XM_028673799.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLV5"/>
    <dbReference type="GeneID" id="39729629"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00110300"/>
    <dbReference type="OMA" id="YCLFICL"/>
    <dbReference type="OrthoDB" id="19045at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046404">
        <property type="term" value="F:ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046403">
        <property type="term" value="F:polynucleotide 3'-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013954">
        <property type="entry name" value="PNK3P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12083">
        <property type="entry name" value="BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12083:SF9">
        <property type="entry name" value="BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08645">
        <property type="entry name" value="PNK3P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="478" mass="58099" checksum="2A0A9AEBE6205498" modified="2017-02-15" version="1">MALKFDSFTNLRIKKSVCIKYLKFLFYLKRYNFENKWNRYYCCLFQTIDEKTTLKKLVLHKFSNNFEKIKKKEILFKKYLSYLISKPIKIASFDFDGTLINSHFNKHKNNLLYDKNVLNTLYNLKNEYKIIIFSNQTNVSSCVHDYDHLRFQKLPNFFLKIRNFKNSLKYFYTLFCDTKRSNFSYLNNSHKTKNKLYLFILNLQNKFGKCKSSYLYRKYHSYLLNQITLTPQMCNYLTKKKKNFKTVLNKRYYLKESLRNNKRNKLNFLYYFFSIGKYGIEDLDIYTKPNVGQFALYICLEAIKYLIILNFYFKNSFELIKKEISNIENKELRSFILLSIDIFNIDEIRELTKNIKRKNFYIDKISLKILDIYVNFLLKKTKPYIFVKQKYPNSILIDFFLNDQITTNIQNKKEIWNLLNDNENLKYLIFCLIYKNKIMKNLMKQFSNLLFNFKSSFYVGNNIGRPFDKSDIDLKVIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM30</accession>
    <name>A0A1J1GM30_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Translation initiation factor IF-3, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">IF3a</name>
        <name evidence="6" type="ORF">PGAL8A_00118400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IF-3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526300.1">
        <property type="nucleotide sequence ID" value="XM_028674688.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM30"/>
    <dbReference type="GeneID" id="39729709"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00118400"/>
    <dbReference type="OMA" id="ERYMQEK"/>
    <dbReference type="OrthoDB" id="21573at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032790">
        <property type="term" value="P:ribosome disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.10">
        <property type="entry name" value="Translation initiation factor 3 (IF-3), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036788">
        <property type="entry name" value="T_IF-3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001288">
        <property type="entry name" value="Translation_initiation_fac_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019815">
        <property type="entry name" value="Translation_initiation_fac_3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10938">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10938:SF0">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00707">
        <property type="entry name" value="IF3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55200">
        <property type="entry name" value="Translation initiation factor IF3, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="domain" description="Translation initiation factor 3 C-terminal" evidence="5">
        <location>
            <begin position="73"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="162" mass="19530" checksum="A1A2AD6D1CE34FF8" modified="2017-02-15" version="1">MLLHLFFFLIFYVFFILLYYNGYGYCFYQSKISYKFFYLKEANDDAKYSNGYDRYLQEKKMKQLKQKVENKPVKQLRITPRIAMNDLLIKINSAKQFLLKRHRVKFILTLKGREYTNKENVNKIFSKIAEELKNFGISETIRQNGNVVSQLFNLKAKRKNET</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM60</accession>
    <name>A0A1J1GM60_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00118700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the KRI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526303.1">
        <property type="nucleotide sequence ID" value="XM_028674698.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM60"/>
    <dbReference type="GeneID" id="39729712"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00118700"/>
    <dbReference type="OMA" id="WDNYDPR"/>
    <dbReference type="OrthoDB" id="10252032at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02249">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018034">
        <property type="entry name" value="Kri1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024626">
        <property type="entry name" value="Kri1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14490:SF5">
        <property type="entry name" value="PROTEIN KRI1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14490">
        <property type="entry name" value="ZINC FINGER, ZZ TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12936">
        <property type="entry name" value="Kri1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00569">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ZZ-type" evidence="6">
        <location>
            <begin position="535"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="domain" description="Kri1-like C-terminal" evidence="7">
        <location>
            <begin position="611"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="101"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="424"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="113"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="130"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="424"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="445"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="471"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="686" mass="82289" checksum="EF6CB17EB2A701D6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMK5</accession>
    <name>A0A1J1GMK5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00119100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526307.1">
        <property type="nucleotide sequence ID" value="XM_028674703.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMK5"/>
    <dbReference type="GeneID" id="39729716"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00119100"/>
    <dbReference type="OrthoDB" id="343358at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="387" mass="46057" checksum="C4245A50D297A416" modified="2017-02-15" version="1">MWSIFNNEDLSLNLEKKNEKRKTFEKIRNKNLLNKRSYGSFSHYDSKNFNKTIDDKIRTLKKHFRKNYRIIRTNLLKLIKIIKKFPEANNEKDKPENESISIDIELIKKLNKIINKIDIEQLKSKKRIRKNRFKNTHALHSNLSKRSFPSKIFSIQKNDSFKNNINVIKKKYSKRNLLLNTTNNIRNIHKQNSYENGGLLYCNNLKNNYYYMNLKNKKQKNSNFYNDTNDVSVTDFYIYSTLNASFNRLNSMNKKKKKLNLLNIQGNNIYLKKENTLTDYNNIENSLKNRSLQNVPYMKNYNILSSPYLHNLTEHFYSPKKKQQKKNIYSNKQKLKKFVKDEKIRSLLRTATNEDELLKAINVAKIAGLDFEAKLGNKKLQKLKSIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMS0</accession>
    <name>A0A1J1GMS0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein L19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00143200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526548.1">
        <property type="nucleotide sequence ID" value="XM_028674970.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMS0"/>
    <dbReference type="GeneID" id="39729956"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00143200"/>
    <dbReference type="OMA" id="NRVWIDP"/>
    <dbReference type="OrthoDB" id="5407653at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01417">
        <property type="entry name" value="Ribosomal_L19e_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.240:FF:000001">
        <property type="entry name" value="Ribosomal protein L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1650.10:FF:000001">
        <property type="entry name" value="Ribosomal protein L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01475">
        <property type="entry name" value="Ribosomal_eL19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035970">
        <property type="entry name" value="60S_ribosomal_eL19_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039547">
        <property type="entry name" value="Ribosomal_eL19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023638">
        <property type="entry name" value="Ribosomal_eL19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000196">
        <property type="entry name" value="Ribosomal_eL19_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015972">
        <property type="entry name" value="Ribosomal_eL19_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033935">
        <property type="entry name" value="Ribosomal_eL19_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057259">
        <property type="entry name" value="Ribosomal_L19e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057260">
        <property type="entry name" value="Ribosomal_L19e_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006343">
        <property type="entry name" value="PRK08570.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10722">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01280">
        <property type="entry name" value="Ribosomal_L19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25476">
        <property type="entry name" value="Ribosomal_L19e_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01416">
        <property type="entry name" value="Ribosomal_L19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48140">
        <property type="entry name" value="Ribosomal protein L19 (L19e)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00526">
        <property type="entry name" value="RIBOSOMAL_L19E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein eL19" evidence="5">
        <location>
            <begin position="2"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="182" mass="21706" checksum="8164E8C624C94144" modified="2017-02-15" version="1">MSLKLQKRLAASVLKCGKNRIWIDPNEISEIALANSRFSIRKLYKEGLILKKPQKVHSRARVRLYKLAKRKGRHMGIGKRRGTKNARTNQKTLWIKRQRVLRRLLKRFRDSKKIDRHLYHSFYLKCKGNQFKNKRTLIEAIQREKAETLKKKAIADQLEAKRLKAQVLRNRRKLKKDKETLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMZ9</accession>
    <name>A0A1J1GMZ9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">6-cysteine protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00141300</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cell surface</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526529.1">
        <property type="nucleotide sequence ID" value="XM_028674949.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMZ9"/>
    <dbReference type="GeneID" id="39729937"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00141300"/>
    <dbReference type="OMA" id="FGCDFDH"/>
    <dbReference type="OrthoDB" id="369273at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2860">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010884">
        <property type="entry name" value="6_CYS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038160">
        <property type="entry name" value="6_CYS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07422">
        <property type="entry name" value="s48_45"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00970">
        <property type="entry name" value="s48_45"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51701">
        <property type="entry name" value="6_CYS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012972620" evidence="9">
        <location>
            <begin position="24"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="295"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="10">
        <location>
            <begin position="21"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="10">
        <location>
            <begin position="161"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG93707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="314" mass="36537" checksum="6C95F70925720CC9" modified="2017-02-15" version="1">MLTYFFTLFLIIYFLYILCKVKGDCDFSSDSLNLSVSEIIPKDEETYLSNIKYCVKFTKGFEILTFICPKKSINYEGIEVRPFNCFETVRINGRHENLGELLEGSVFKNSETDSTIVRKVFIPPLIKEDILFECTCDNSLTFKGKHMGSRGIMRVQLKKNKIFGCDFDHNGNITQKNPFIYHEKSTKNSNETIICNVIVNSSEVILGLICPKDYKLFPDNCFENVLHENKIVKISELVPHDLKLHTNEKERSSFASFTLNKNEKTKGFSCQCVKNKNSRLYAYFEFDLNYKSSSFHIYILSFIIFILFLILFFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN00</accession>
    <name>A0A1J1GN00_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00154200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526654.1">
        <property type="nucleotide sequence ID" value="XM_028675087.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN00"/>
    <dbReference type="GeneID" id="39730066"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00154200"/>
    <dbReference type="OMA" id="NIKDYGN"/>
    <dbReference type="OrthoDB" id="430577at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="93" mass="11319" checksum="D12C5263A2940377" modified="2017-02-15" version="1">MGKVNIKDYGNICKWFKKLSNKKPMPLLPENKNDRLKKFTNFSLYHIMDKYEFLPNFILQTEYLYPILYKNPEILKQSYFNHHKFSNLQNKPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN54</accession>
    <name>A0A1J1GN54_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00160500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526718.1">
        <property type="nucleotide sequence ID" value="XM_028675159.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN54"/>
    <dbReference type="GeneID" id="39730130"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00160500"/>
    <dbReference type="OrthoDB" id="372668at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="298" mass="36359" checksum="C231A4E8B998E683" modified="2017-02-15" version="1">MKNIKNKNILNKNYNNNNDINNLNLENLKLQLFKEYNKKKPIKENLYELSNKNKKYKNYKNKEININTNIKLNNKNYMKTKNNIPFNVSSTSNINNNFYKDCSAPYYNQKKNENYEKRECFTKYENSENQEINDLENEVIDFKNVLIYRHIDNDSFHLNKNHYNEYENNEFNDNLENSLEDTFFDIHTQNEIEKNHVNLNSNIDKNNNTTYKNFKNDENNEKQLLLDHIKRLEYQNNIFLNNLLNMYYVCVDYMKMQDEKIKKKDEIILFQNKIINNLRKREKLDDTNIYNNLDCNYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNH4</accession>
    <name>A0A1J1GNH4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nucleoside diphosphate kinase</fullName>
            <ecNumber evidence="9">2.7.4.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00173000</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:44640"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the NDK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.6" evidence="9"/>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526844.1">
        <property type="nucleotide sequence ID" value="XM_028670053.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNH4"/>
    <dbReference type="GeneID" id="39730257"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00173000"/>
    <dbReference type="OMA" id="NIWFKAD"/>
    <dbReference type="OrthoDB" id="2162449at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006241">
        <property type="term" value="P:CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006183">
        <property type="term" value="P:GTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006228">
        <property type="term" value="P:UTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04413">
        <property type="entry name" value="NDPk_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.141:FF:000002">
        <property type="entry name" value="Nucleoside diphosphate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="entry name" value="Nucleoside diphosphate kinase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034907">
        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001564">
        <property type="entry name" value="Nucleoside_diP_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023005">
        <property type="entry name" value="Nucleoside_diP_kinase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001908">
        <property type="entry name" value="PRK00668.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11349">
        <property type="entry name" value="NUCLEOSIDE DIPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01243">
        <property type="entry name" value="NUCDPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="Nucleoside diphosphate kinase, NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00469">
        <property type="entry name" value="NDPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51374">
        <property type="entry name" value="NDPK_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleoside diphosphate kinase-like" evidence="10">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="active site" description="Pros-phosphohistidine intermediate" evidence="7">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="3"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG94023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="143" mass="16282" checksum="0DEF4C50AC16472B" modified="2017-02-15" version="1">MVKPDGVQRGLVGSIIKRFERKGYKMIAIKMLNPSKEILKEHYKDLCEKSFFSSLIEYVGKGPVVAMVWEGVDIVNQGRKLIGETNPLNSNVGTIRGDFCLEVGKNVIHGSDSVASANREINIWFKPEELVQWNYHLKEWICE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNI0</accession>
    <name>A0A1J1GNI0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00173800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526852.1">
        <property type="nucleotide sequence ID" value="XM_028670062.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNI0"/>
    <dbReference type="GeneID" id="39730265"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00173800"/>
    <dbReference type="OMA" id="SCKTCIK"/>
    <dbReference type="OrthoDB" id="384313at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012430206" evidence="1">
        <location>
            <begin position="25"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="331" mass="39851" checksum="03301B330AE24344" modified="2017-02-15" version="1">MKNNLSYSVFLFYFFIICYNKISSINVENDYISDLVKLGIFYRNTSTIKKEVYEKINQAHNTFSSCRTCIKLIQLLNKIIKKKKEKYIDIAIEETLELNLCSSELWKEYFNYDEILYNEYILEYCENTFKIIKDNIEENVYELHKNVELFYEKVCGNIDQICKTAIKEEKLNYENQMKTKFIFQLYSKYLIEEENFSYTDDGLPYKLIETNNNNLKLKKSNFAIIQSEIKIIHKNILYNDFKDNHFRLIKIDKLEDKVQNLFLKMKELDMFIFLLYNEFSNEGIIPNDSILEIKIKIQKIIYDIDEVATKNFKNNLIIDEKFLLNKHSFKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNL4</accession>
    <name>A0A1J1GNL4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Plasmodium RESA N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00177700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000021">
        <property type="protein sequence ID" value="CRG94065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526886.1">
        <property type="nucleotide sequence ID" value="XM_028670101.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNL4"/>
    <dbReference type="GeneID" id="39730304"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00177700"/>
    <dbReference type="OMA" id="CEIGRIW"/>
    <dbReference type="OrthoDB" id="10553403at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.180">
        <property type="entry name" value="Plasmodium RESA, N-terminal helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019111">
        <property type="entry name" value="PRESA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044885">
        <property type="entry name" value="PRESA_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36193">
        <property type="entry name" value="PHISTB DOMAIN-CONTAINING RESA-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36193:SF23">
        <property type="entry name" value="PHISTB DOMAIN-CONTAINING RESA-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09687">
        <property type="entry name" value="PRESAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="Plasmodium RESA N-terminal" evidence="2">
        <location>
            <begin position="102"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="239" mass="28569" checksum="E5BEB5BAB1182051" modified="2017-02-15" version="1">MEYSNVQDNNLSKTCIDDDKVTLKKNSICSTGKQDIIFKKLNYRNIVHSRLFLVSILFLLFFFFQDINKFQDDIKSGIQFKNINSRKLAELDLKNYNDDFHDTSEGVPHERVLSKWKDFRDKQRSTLNDEIKKCLDDLFEKSEIHDLSEKERKELWDQFLKEFFSTLADTDGTNYQEIYDLCREGLCSREDFNNFLNKNFTLWNSIKDDLKRKWDDFLSTNIKLLKDQVKLVSYNTIEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNR0</accession>
    <name>A0A1J1GNR0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00174400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526858.1">
        <property type="nucleotide sequence ID" value="XM_028670069.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNR0"/>
    <dbReference type="GeneID" id="39730271"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00174400"/>
    <dbReference type="OMA" id="HYKYLIK"/>
    <dbReference type="OrthoDB" id="370969at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="488"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="514"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="532"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="557"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="745" mass="88558" checksum="0F0809CB652F797B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP23</accession>
    <name>A0A1J1GP23_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">DNA repair endonuclease, putative</fullName>
            <ecNumber evidence="12">3.1.21.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ERCC4</name>
        <name evidence="12" type="ORF">PGAL8A_00175300</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the XPF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.1" evidence="12"/>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526867.1">
        <property type="nucleotide sequence ID" value="XM_028670079.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730280"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00175300"/>
    <dbReference type="OMA" id="VTEKNMH"/>
    <dbReference type="OrthoDB" id="361020at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000110">
        <property type="term" value="C:nucleotide-excision repair factor 1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004530">
        <property type="term" value="F:deoxyribonuclease I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000014">
        <property type="term" value="F:single-stranded DNA endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901255">
        <property type="term" value="P:nucleotide-excision repair involved in interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20078">
        <property type="entry name" value="XPF_nuclease_XPF_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10130:FF:000002">
        <property type="entry name" value="DNA repair endonuclease XPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006166">
        <property type="entry name" value="ERCC4_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047520">
        <property type="entry name" value="XPF_nuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10150">
        <property type="entry name" value="DNA REPAIR ENDONUCLEASE XPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10150:SF0">
        <property type="entry name" value="DNA REPAIR ENDONUCLEASE XPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02732">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00891">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="Restriction endonuclease-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="RuvA domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 12" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERCC4" evidence="11">
        <location>
            <begin position="1105"/>
            <end position="1185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="778"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1302"/>
            <end position="1328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="780"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1302"/>
            <end position="1323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG94046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1445" mass="174100" checksum="49B3B73D2F6D5B89" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP88</accession>
    <name>A0A1J1GP88_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AAA family ATPase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00079700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525917.1">
        <property type="nucleotide sequence ID" value="XM_028670433.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP88"/>
    <dbReference type="GeneID" id="39729322"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00079700"/>
    <dbReference type="OMA" id="WEDNINI"/>
    <dbReference type="OrthoDB" id="391872at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076:SF97">
        <property type="entry name" value="ATP-DEPENDENT ZINC METALLOPROTEASE YME1L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076">
        <property type="entry name" value="METALLOPROTEASE M41 FTSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="520"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="991" mass="118269" checksum="401CCAC0B3262E51" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPC0</accession>
    <name>A0A1J1GPC0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">diphthine methyl ester synthase</fullName>
            <ecNumber evidence="4">2.1.1.314</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00385200</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 4 S-adenosyl-L-methionine = diphthine methyl ester-[translation elongation factor 2] + 4 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:42652"/>
            <dbReference type="Rhea" id="RHEA-COMP:9749"/>
            <dbReference type="Rhea" id="RHEA-COMP:10173"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73995"/>
            <dbReference type="ChEBI" id="CHEBI:79005"/>
            <dbReference type="EC" id="2.1.1.314"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the diphthine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.314" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526969.1">
        <property type="nucleotide sequence ID" value="XM_028670192.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPC0"/>
    <dbReference type="GeneID" id="39732382"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00385200"/>
    <dbReference type="OMA" id="CTGLEMY"/>
    <dbReference type="OrthoDB" id="2516at2759"/>
    <dbReference type="UniPathway" id="UPA00559"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141133">
        <property type="term" value="F:diphthine methyl ester synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd11647">
        <property type="entry name" value="DHP5_DphB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.950.10:FF:000004">
        <property type="entry name" value="Diphthine synthase putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1010.10:FF:000004">
        <property type="entry name" value="Putative diphthine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="entry name" value="Cobalt-precorrin-4 Transmethylase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="entry name" value="Methyltransferase, Cobalt-precorrin-4 Transmethylase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01084">
        <property type="entry name" value="Diphthine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004551">
        <property type="entry name" value="Dphthn_synthase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00522">
        <property type="entry name" value="dph5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10882:SF0">
        <property type="entry name" value="DIPHTHINE METHYL ESTER SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10882">
        <property type="entry name" value="DIPHTHINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036432">
        <property type="entry name" value="Diphthine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="Tetrapyrrole methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Tetrapyrrole methylase" evidence="10">
        <location>
            <begin position="3"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="113"/>
            <end position="114"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR036432-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG94148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="271" mass="31327" checksum="E0DC0E2F781C78F7" modified="2017-02-15" version="1">MVLYIIGLGLGDEKDITVKGKELIEKSDIVYLESYTSILFISKEDLEKFYKKKIYEVDRNFAEENCEEILNEAKNKSVSFLVVGDPLCATTHHDIILRAKKENIDVHIIHNTSIISAIGESGMQLYNFGQIVSIPFFEKDYKPTSFYDKIKINLDNNFHTLCLLDIKIKERTIENIMKNRNIFEPPRYMTINEAIDQLLYCEDIHKKNVITKNTLGIAMVRIGSNNQQIISGNLLTLKSLNYDKPLHSLIICASTLHDIEKEYFNIYLHKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPC1</accession>
    <name>A0A1J1GPC1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">T-complex protein 1 subunit theta, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CCT8</name>
        <name evidence="8" type="ORF">PGAL8A_00404700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527164.1">
        <property type="nucleotide sequence ID" value="XM_028670408.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPC1"/>
    <dbReference type="GeneID" id="39732577"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00404700"/>
    <dbReference type="OMA" id="WGLKYAV"/>
    <dbReference type="OrthoDB" id="1748577at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03341">
        <property type="entry name" value="TCP1_theta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000008">
        <property type="entry name" value="T-complex protein 1 subunit theta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012721">
        <property type="entry name" value="Chap_CCT_theta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02346">
        <property type="entry name" value="chap_CCT_theta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="542" mass="61063" checksum="95F6FB37F811C4CB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPJ7</accession>
    <name>A0A1J1GPJ7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DEAD/DEAH box helicase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00406600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527183.1">
        <property type="nucleotide sequence ID" value="XM_028670430.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732596"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00406600"/>
    <dbReference type="OMA" id="CRCHRIG"/>
    <dbReference type="OrthoDB" id="5857104at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000047">
        <property type="entry name" value="DEAD/DEAH box helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001923">
        <property type="entry name" value="DEAD/DEAH box helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10799">
        <property type="entry name" value="SNF2/RAD54 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="3">
        <location>
            <begin position="675"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="4">
        <location>
            <begin position="976"/>
            <end position="1204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1035"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1277"/>
            <end position="1301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1602"/>
            <end position="1652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="260"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1046"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1286"/>
            <end position="1295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1652" mass="195972" checksum="097228FF92559412" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPQ0</accession>
    <name>A0A1J1GPQ0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00398000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527097.1">
        <property type="nucleotide sequence ID" value="XM_028670335.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPQ0"/>
    <dbReference type="GeneID" id="39732510"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00398000"/>
    <dbReference type="OMA" id="HINAYII"/>
    <dbReference type="OrthoDB" id="391619at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012204618" evidence="2">
        <location>
            <begin position="26"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="165"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="894" mass="107261" checksum="58D1BACB7C7DFF50" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPT3</accession>
    <name>A0A1J1GPT3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein kinase, putative</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00182100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527250.1">
        <property type="nucleotide sequence ID" value="XM_028670504.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730348"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00182100"/>
    <dbReference type="OMA" id="LLEYMHA"/>
    <dbReference type="OrthoDB" id="371216at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1479"/>
            <end position="1733"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1733" mass="205737" checksum="3F8B148630596C43" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPZ8</accession>
    <name>A0A1J1GPZ8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00198800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527406.1">
        <property type="nucleotide sequence ID" value="XM_028670678.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPZ8"/>
    <dbReference type="GeneID" id="39730515"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00198800"/>
    <dbReference type="OMA" id="YNHWLRN"/>
    <dbReference type="OrthoDB" id="438538at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="180" mass="22419" checksum="6830B34940EC7AC5" modified="2017-02-15" version="1">MFIFENAQHYFNFFRNFNGCYTDNKLLRYFFKKSYNNWFNDPSQYNYYFISYYAVAISISVLLRHLLFNPDVHFRRQDKRRNIIDRYQHHAYSLPYFNHWLRNFSQSFKSALIDNEPDYQDVDPWCFRPKRTPFYGRFPFFLEVPKYNVDNPNYEKNSHSYMQKYYESIGYIPQSEQKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ38</accession>
    <name>A0A1J1GQ38_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00202600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527444.1">
        <property type="nucleotide sequence ID" value="XM_028670719.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ38"/>
    <dbReference type="GeneID" id="39730552"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00202600"/>
    <dbReference type="OMA" id="ICTKIDN"/>
    <dbReference type="OrthoDB" id="361494at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016593">
        <property type="term" value="C:Cdc73/Paf1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051510">
        <property type="entry name" value="SKI8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44090:SF1">
        <property type="entry name" value="SUPERKILLER COMPLEX PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44090">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="266"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="345"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="347"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="764" mass="89961" checksum="2A534E24F7297CED" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQE1</accession>
    <name>A0A1J1GQE1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00121800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526333.1">
        <property type="nucleotide sequence ID" value="XM_028674731.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQE1"/>
    <dbReference type="GeneID" id="39729743"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00121800"/>
    <dbReference type="OrthoDB" id="10606205at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="654"/>
            <end position="683"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="845" mass="100779" checksum="49843A2A83D158FE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQE4</accession>
    <name>A0A1J1GQE4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00188400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000026">
        <property type="protein sequence ID" value="CRG94489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527307.1">
        <property type="nucleotide sequence ID" value="XM_028670568.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQE4"/>
    <dbReference type="GeneID" id="39730411"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00188400"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006496">
        <property type="entry name" value="CHP01606_Plasmodium_spp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09688">
        <property type="entry name" value="Wx5_PLAF3D7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="224" mass="26739" checksum="D0EEEDFBD4BDA535" modified="2017-02-15" version="1">MKILTLYLKITTFLLLIWMFQCFYNCYSYKTLIDKNISQTKNELKYERVLTEGDIADEKQNYAEGSLEECALDSKKNKCNVPDLCENPRDYWNKVITPQLWEQFNQETSGMDPKLKEDKWNIEWNKISAKKVNDLSSIFNRTDISKEEKKNLIFSVMNELSSEFVKFLYECKKEMRDNKTGSESKKEIRENKTESESKNVQGKKKMKNNKSKIFEFLFKRFDNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQH5</accession>
    <name>A0A1J1GQH5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ubiquitin carboxyl-terminal hydrolase 1, putative</fullName>
            <ecNumber evidence="4">3.4.19.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">UBP1</name>
        <name evidence="4" type="ORF">PGAL8A_00100400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526120.1">
        <property type="nucleotide sequence ID" value="XM_028672688.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729528"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00100400"/>
    <dbReference type="OrthoDB" id="286820at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="USP" evidence="3">
        <location>
            <begin position="2512"/>
            <end position="2827"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="180"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="432"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="937"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1331"/>
            <end position="1390"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="59"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1083"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="180"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="192"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="229"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="443"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="937"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="948"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1343"/>
            <end position="1363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1370"/>
            <end position="1387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2837" mass="339403" checksum="DC0AECD634FAB94A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQK6</accession>
    <name>A0A1J1GQK6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Haloacid dehalogenase-like hydrolase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">HAD2</name>
        <name evidence="1" type="ORF">PGAL8A_00127400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526389.1">
        <property type="nucleotide sequence ID" value="XM_028674794.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQK6"/>
    <dbReference type="GeneID" id="39729799"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00127400"/>
    <dbReference type="OMA" id="GHENAES"/>
    <dbReference type="OrthoDB" id="27226at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000150">
        <property type="entry name" value="Cof"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00099">
        <property type="entry name" value="Cof-subfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10000:SF8">
        <property type="entry name" value="HAD SUPERFAMILY HYDROLASE-LIKE, TYPE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10000">
        <property type="entry name" value="PHOSPHOSERINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08282">
        <property type="entry name" value="Hydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01144">
        <property type="entry name" value="C2.B.4:_PGP_Like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01140">
        <property type="entry name" value="C2.B:_Phosphomannomutase_and_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="295" mass="33547" checksum="5495040CEE476F58" modified="2017-02-15" version="1">MAADKIFNTDVEETLKGADIKLLLIDFDGTLFVDKDIKVPEENIEAIKLAIEKGYMVSVCTGRSKVGILSAFGEENLKKMNFYGMPGVYINGTIVYDQIGYTLLDETIETDVYAELIRYLVQNNLVNQTIFYRGESNYVTEDNKYADFMQKMYSENRSIIIRQNEILKYRTMNKLMIVLDPSESKIVIENLKRNFGKKLTIFTTYNGHAEVTKLGHDKYTGISYLLKHYNISDDQVLVVGDAENDIAMLSNFKYSFAVANATESAKSFAKCVIPLTHKEGAVAYLLKKVFELKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQQ2</accession>
    <name>A0A1J1GQQ2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GTP-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00218400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527602.1">
        <property type="nucleotide sequence ID" value="XM_028670895.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQQ2"/>
    <dbReference type="GeneID" id="39730711"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00218400"/>
    <dbReference type="OMA" id="FKYKSYR"/>
    <dbReference type="OrthoDB" id="1696305at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050896">
        <property type="entry name" value="Mito_lipid_metab_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048422">
        <property type="entry name" value="NOA1/YqeH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46434">
        <property type="entry name" value="GENETIC INTERACTOR OF PROHIBITINS 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46434:SF1">
        <property type="entry name" value="GENETIC INTERACTOR OF PROHIBITINS 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21516">
        <property type="entry name" value="YqeH-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="614"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="domain" description="G" evidence="2">
        <location>
            <begin position="509"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="domain" description="NOA1/YqeH-like C-terminal" evidence="3">
        <location>
            <begin position="632"/>
            <end position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="813" mass="96052" checksum="0A389A64736A5A95" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQV2</accession>
    <name>A0A1J1GQV2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00136800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526485.1">
        <property type="nucleotide sequence ID" value="XM_028674900.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQV2"/>
    <dbReference type="GeneID" id="39729893"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00136800"/>
    <dbReference type="OMA" id="HTCCILA"/>
    <dbReference type="OrthoDB" id="372093at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1091" mass="130604" checksum="8F0C2A0A29100867" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQV6</accession>
    <name>A0A1J1GQV6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00220500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527623.1">
        <property type="nucleotide sequence ID" value="XM_028670918.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQV6"/>
    <dbReference type="GeneID" id="39730732"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00220500"/>
    <dbReference type="OMA" id="HIMGTCV"/>
    <dbReference type="OrthoDB" id="377630at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="465"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="580"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="589"/>
            <end position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="743" mass="88169" checksum="8894ED1C659505B8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR55</accession>
    <name>A0A1J1GR55_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Early transcribed membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ETRAMP</name>
        <name evidence="2" type="ORF">PGAL8A_00122900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526344.1">
        <property type="nucleotide sequence ID" value="XM_028674743.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR55"/>
    <dbReference type="GeneID" id="39729754"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00122900"/>
    <dbReference type="OrthoDB" id="10545087at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006389">
        <property type="entry name" value="Early_transc_mb_plasmodium"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01495">
        <property type="entry name" value="ETRAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09716">
        <property type="entry name" value="ETRAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="173" mass="19641" checksum="D688BD84CA071E3E" modified="2017-02-15" version="1">MKVSMILHLFNILVAINLLAPCFCLNKKDNVEDNNDIISITESIEKSRKKKIMYTCAALATTLAAVTGIALGIYFTRDKRRSVWENDDLGNAASEIIDKIVDEGSKNGQIALENGLDLEKVIKNKDIKNALKTYLEKSETKFSGFQKRELYHYVPFISHIIRHKLKNNDSYDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR71</accession>
    <name>A0A1J1GR71_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Phospholipid-transporting ATPase, putative</fullName>
            <ecNumber evidence="12">3.6.3.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00124500</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.1" evidence="12"/>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526360.1">
        <property type="nucleotide sequence ID" value="XM_028674761.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729770"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00124500"/>
    <dbReference type="OMA" id="QRAPADC"/>
    <dbReference type="OrthoDB" id="377733at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140326">
        <property type="term" value="F:ATPase-coupled intramembrane lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032631">
        <property type="entry name" value="P-type_ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF5">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16209">
        <property type="entry name" value="PhoLip_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="551"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="593"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="624"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1347"/>
            <end position="1368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1415"/>
            <end position="1439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1475"/>
            <end position="1494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1506"/>
            <end position="1526"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase N-terminal" evidence="10">
        <location>
            <begin position="56"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="9">
        <location>
            <begin position="147"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase C-terminal" evidence="11">
        <location>
            <begin position="1309"/>
            <end position="1535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="293"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="410"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG93538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1542" mass="182559" checksum="7323499B5517051C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR77</accession>
    <name>A0A1J1GR77_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Enkurin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00241500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527830.1">
        <property type="nucleotide sequence ID" value="XM_028671149.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR77"/>
    <dbReference type="GeneID" id="39730943"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00241500"/>
    <dbReference type="OMA" id="THTNFWK"/>
    <dbReference type="OrthoDB" id="371941at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="189"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="263" mass="31196" checksum="32001D53479C6D4B" modified="2017-02-15" version="1">MTTNENEEKLKEDYDDIKYEKPDTHKNFWKSFGLDSKAGKLLYYLYGDNNKINPNLIAPKKFVKKEKDVKEIKIEKSFRNPQINYPSYKKKIEKENPIDKIPHKKPLSKILEETKNYESIKELPIKIGRNREEEKKKLNVIFLEQKCKVLPPSCAPLVLTEEEKKEIIKNAEKRYLDLSESNSREDKIIDALKNYRTELKVELNKKINEFKNIMCDNNTSNNKPGENTRRLNELEYQKINLKNEIEQCKKNIKKTDDILNSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRB7</accession>
    <name>A0A1J1GRB7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00129300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526408.1">
        <property type="nucleotide sequence ID" value="XM_028674815.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRB7"/>
    <dbReference type="GeneID" id="39729818"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00129300"/>
    <dbReference type="OMA" id="DICSNFF"/>
    <dbReference type="OrthoDB" id="392431at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="737" mass="90009" checksum="70E4EF5977C327E8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRN2</accession>
    <name>A0A1J1GRN2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Vacuolar ATP synthase subunit d, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00253000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the V-ATPase D subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527938.1">
        <property type="nucleotide sequence ID" value="XM_028671269.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRN2"/>
    <dbReference type="GeneID" id="39731058"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00253000"/>
    <dbReference type="OMA" id="REEFFRM"/>
    <dbReference type="OrthoDB" id="7676488at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.3240:FF:000006">
        <property type="entry name" value="V-type proton ATPase subunit D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002699">
        <property type="entry name" value="V_ATPase_D"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00309">
        <property type="entry name" value="V_ATPase_subD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11671">
        <property type="entry name" value="V-TYPE ATP SYNTHASE SUBUNIT D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01813">
        <property type="entry name" value="ATP-synt_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="252" mass="28484" checksum="0FEEBB8E5DF70375" modified="2017-02-15" version="1">MGALDESTPVPSRITLQLMKQKKKSAFQGYSLLKKKSDALFIHFRDVLKDIVKTKVKVGEEMRNASFALAKAVWAAGDFKGQIIEGIKRPAVTLSLSTNNVAGVKLPIFQVQIDPTVDVLGNLGVASGGQVINNTRENYLQCLNMLVKLASMQVAFFSLDEEIKMTNRRVNALNNIVLPRLDGGINYIIKELDEIEREEFYRLKKIKEKKIDKLKDSNIEYTMDGNAFKNNYNNVKRNDEFICAQMDDDVIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRR2</accession>
    <name>A0A1J1GRR2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00169100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526805.1">
        <property type="nucleotide sequence ID" value="XM_028670010.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730218"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00169100"/>
    <dbReference type="OMA" id="CRDKNED"/>
    <dbReference type="OrthoDB" id="387070at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="371"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="503"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="767"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1210"/>
            <end position="1274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="75"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="767"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="788"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="817"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1221"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1236"/>
            <end position="1245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1252"/>
            <end position="1274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1428" mass="169515" checksum="6F424AB72102D230" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRS5</accession>
    <name>A0A1J1GRS5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Casein kinase II subunit beta</fullName>
            <shortName evidence="2">CK II beta</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CK2beta2</name>
        <name evidence="4" type="ORF">PGAL8A_00253500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the casein kinase 2 subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527943.1">
        <property type="nucleotide sequence ID" value="XM_028671274.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRS5"/>
    <dbReference type="GeneID" id="39731063"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00253500"/>
    <dbReference type="OMA" id="YCPRCCE"/>
    <dbReference type="OrthoDB" id="3971593at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005956">
        <property type="term" value="C:protein kinase CK2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019887">
        <property type="term" value="F:protein kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1820.10:FF:000007">
        <property type="entry name" value="Casein kinase II subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.20:FF:000001">
        <property type="entry name" value="Casein kinase II subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1820.10">
        <property type="entry name" value="protein kinase ck2 holoenzyme, chain C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016149">
        <property type="entry name" value="Casein_kin_II_reg-sub_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035991">
        <property type="entry name" value="Casein_kinase_II_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000704">
        <property type="entry name" value="Casein_kinase_II_reg-sub"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11740">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11740:SF0">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01214">
        <property type="entry name" value="CK_II_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00472">
        <property type="entry name" value="CASNKINASEII"/>
    </dbReference>
    <dbReference type="SMART" id="SM01085">
        <property type="entry name" value="CK_II_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57798">
        <property type="entry name" value="Casein kinase II beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="43"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="180"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="64"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="357" mass="42026" checksum="F991C0B6659C24AF" modified="2017-02-15" version="1">MEYISNDESSNEILQENMAGEIELSDTSFCNAIKNDDFKEAEYIKEENEENYILDGEKQKEKEDENEEEEEEEEEEEEEEEEEEEEEEEEEEEEDDDDDDDDDDDDDDDDDDDDDDDEYDEDDFNEATVSWIEWFCQLKQNIFLVEVDEDFIRDEFNLIGLQNKVPHFKKLLKIILDEDDDEDDDDDEDDDYDEDDDEINRGSEELYKNKDIYEQNAACLYGLIHSRFILTSKGLALMREKYKAGIYGTCPSIYCDNAKLLPTAISEVPKFLSPLLYCPRCCETYYPHKNSLLNQLDGSYFGTSFASFFALSFNITSDKKKVYYTPQICGFTINRDMRETLYMDVNKDNSESSEEYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS51</accession>
    <name>A0A1J1GS51_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SECIS-binding protein 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">SBP2</name>
        <name evidence="2" type="ORF">PGAL8A_00009000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528134.1">
        <property type="nucleotide sequence ID" value="XM_028671486.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS51"/>
    <dbReference type="GeneID" id="39728612"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00009000"/>
    <dbReference type="OrthoDB" id="263617at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003730">
        <property type="term" value="F:mRNA 3'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043021">
        <property type="term" value="F:ribonucleoprotein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035368">
        <property type="term" value="F:selenocysteine insertion sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040051">
        <property type="entry name" value="SECISBP2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13284:SF4">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13284">
        <property type="entry name" value="GH01354P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="1">
        <location>
            <begin position="328"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="434" mass="52366" checksum="A2799A15C8AC07DA" modified="2017-02-15" version="1">MIDMLNKRLDIEKEKGNFYFLPKHLKKKKKSKLKKMIILEKEVKNKIYFDILQKKQNENIAKDLCYNLIKNQIKWKLKNYTYKFYCRKYMQIYIFKGKRIGKRISFINNYDIKDNNYMNIIEEINNLKNFILLNKKYLKKKKKLDKIKSYKKNMKIHNSKNKVANIQNEYFHNDIKYNNEENKTQKYEINKMRIKEMNYNVGKENDSNHMRCMLVEQNTSNIKNENIKIIKNYEEKFTKNEIMNRKKLNTEVVNNEKYRIHKSMNENMDKDKIKESIIKNDKILNYIQVSKIEKKIYINDYVDHKITDELNNLVKEFLKKIAKSHEKLLLKKKKRYYLGLKESYKHICINEPKLVIVAPNIEPMVNNAFGDLLEKIIYKCKEKNIPLIYALSKNLLGKCISKSRQSIICVIDNDSYIKECNDIITLANSLKIYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS61</accession>
    <name>A0A1J1GS61_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoglycerate mutase, putative</fullName>
            <ecNumber evidence="2">5.4.2.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00009600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.11" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528140.1">
        <property type="nucleotide sequence ID" value="XM_028671493.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS61"/>
    <dbReference type="GeneID" id="39728618"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00009600"/>
    <dbReference type="OrthoDB" id="496981at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004619">
        <property type="term" value="F:phosphoglycerate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF1">
        <property type="entry name" value="HISTIDINE PHOSPHATASE FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="375"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="432"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1011" mass="119577" checksum="4EC3D1B0B4E0D23A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS85</accession>
    <name>A0A1J1GS85_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glycerol-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.5.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00005700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.5.3" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528103.1">
        <property type="nucleotide sequence ID" value="XM_028671452.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS85"/>
    <dbReference type="GeneID" id="39728579"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00005700"/>
    <dbReference type="OMA" id="PHIVKPM"/>
    <dbReference type="OrthoDB" id="264015at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004368">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.870">
        <property type="entry name" value="Alpha-glycerophosphate oxidase, cap domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031656">
        <property type="entry name" value="DAO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038299">
        <property type="entry name" value="DAO_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000447">
        <property type="entry name" value="G3P_DH_FAD-dep"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11985">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11985:SF15">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16901">
        <property type="entry name" value="DAO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01001">
        <property type="entry name" value="FADG3PDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="domain" description="FAD dependent oxidoreductase" evidence="8">
        <location>
            <begin position="59"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-glycerophosphate oxidase C-terminal" evidence="9">
        <location>
            <begin position="467"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG95292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="619" mass="70787" checksum="B3FEF33F587CB9F6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSN8</accession>
    <name>A0A1J1GSN8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00270800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000040">
        <property type="protein sequence ID" value="CRG95507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528316.1">
        <property type="nucleotide sequence ID" value="XM_028671689.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSN8"/>
    <dbReference type="GeneID" id="39731239"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00270800"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="139" mass="16703" checksum="D81B1ADB28B592BE" modified="2017-02-15" version="1">MKTFTLCLKIFTFLLLIWIFPFFYKYDSSKSLINRDTLQTKIGVKHKRILAEGDKSEKKSSSFETFIDSYPSSEIEMRYVDLVYLMDMYIKCYIANIKSFCVDEVLFNEENEMRYKCRNKILNAYRNNFIDDLCEDCFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSX2</accession>
    <name>A0A1J1GSX2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Adenylate kinase, putative</fullName>
            <ecNumber evidence="6">2.7.4.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">AK1</name>
        <name evidence="6" type="ORF">PGAL8A_00385100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the adenylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.3" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526968.1">
        <property type="nucleotide sequence ID" value="XM_028670191.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSX2"/>
    <dbReference type="GeneID" id="39732381"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00385100"/>
    <dbReference type="OMA" id="HYKVDAA"/>
    <dbReference type="OrthoDB" id="439792at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:AMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000106">
        <property type="entry name" value="Adenylate kinase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006259">
        <property type="entry name" value="Adenyl_kin_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007862">
        <property type="entry name" value="Adenylate_kinase_lid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01351">
        <property type="entry name" value="adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001381">
        <property type="entry name" value="PRK00279.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05191">
        <property type="entry name" value="ADK_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Adenylate kinase active site lid" evidence="5">
        <location>
            <begin position="155"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG94147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="242" mass="27729" checksum="F18C1208BEC6DD02" modified="2017-02-15" version="1">MNDNLENISTIDLLNELKRRYACLSKPDGRYIFLGAPGSGKGTQSLNLKKSHCYCHLSTGDLLREAIEKKSEIGNKVKDIMSEGKLVDDDIVLSLVDEKLKSPQCKKGFILDGYPRNVKQAEDLNKLLQKNQTKLNGVFYFNVPDDVLVKRISGRLIHKPSGRIYHKIFNPPKTPFKDDLTDEPLIQREDDNEEVLKKRLHIFKNETTPLVNYYENKNLLINLDATQPPQDLEKKISQHIDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT43</accession>
    <name>A0A1J1GT43_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00392300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527040.1">
        <property type="nucleotide sequence ID" value="XM_028670271.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT43"/>
    <dbReference type="GeneID" id="39732453"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00392300"/>
    <dbReference type="OrthoDB" id="372681at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="235" mass="27637" checksum="818F3CA1C8C75374" modified="2017-02-15" version="1">MGRHNDKYSCNHRGKSHIKSKKKKEKKSKNNIYVLLFFFSISLILYLNSEKVADFVENFKKNPEISTLSTSTSYTYPMNNGITKKEDDDLIRTFKIATNEEIRNNLLMDTFNIKKFEDDTYKLKFYGDDLINNIEIIKKSNFIFDAINYLIKGMKGSNLYSVNQRDKGSLRNEKEKRYDAGKLKRLIIIKLLKCISVLVFIYIIYRLITLLFKNVINFIFVLIFKIIKYCCCGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT44</accession>
    <name>A0A1J1GT44_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoglycerate mutase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00281200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528423.1">
        <property type="nucleotide sequence ID" value="XM_028671807.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT44"/>
    <dbReference type="GeneID" id="39731345"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00281200"/>
    <dbReference type="OrthoDB" id="496981at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="372"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="439" mass="52497" checksum="6EDEDD308078BFF0" modified="2017-02-15" version="1">MKIFLISLVTIFLTFLIINIIFEYIHIFNLKKHKNKKNTNNKRLLKFFLHIQILKEIIVNSFINFFIKIKVIFHCIYRYVSFNRNKYISIPMSEKDESLINKDNCEIKTIYFIRHSESVWNNTFNKKLTFKTFMNISLVIFYEFIFLFSKKSALIDAPLSTNGIIQSLELSNFLQKEKKNKDGSKQCVVPINQIDISEENAKKYENSSEMIKLQRCDNKKNKTFNNNKVAESNVDMKNVNLKNNNDEYDHEEIINLSIKEHIDVLNKLKYNSVLLCSDLRRTISSCFISFYNRINKFNESIYVLNSLQEISRNPDCVPLLRFFNKYITTDIEKFLHKDVERLFKRNLKIANTYSKSYFLDTLKYIFNNENNIFIIFGHSLWFLLFFNYFLKIPHKAKTYKMQNSSIVVFNIMKCTHENKVNYEIEKNSIRVIYKGFDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT61</accession>
    <name>A0A1J1GT61_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00287100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528482.1">
        <property type="nucleotide sequence ID" value="XM_028671873.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT61"/>
    <dbReference type="GeneID" id="39731404"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00287100"/>
    <dbReference type="OMA" id="RINNCEC"/>
    <dbReference type="OrthoDB" id="372506at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="439"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="604"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="638"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="661"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="686"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="739"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="805"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="833"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="859"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="888"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="947"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="987"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1027"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="520"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1079" mass="130688" checksum="8463C2644A7BEB96" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT67</accession>
    <name>A0A1J1GT67_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00287900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528490.1">
        <property type="nucleotide sequence ID" value="XM_028671882.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT67"/>
    <dbReference type="GeneID" id="39731412"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00287900"/>
    <dbReference type="OMA" id="WPERKSC"/>
    <dbReference type="OrthoDB" id="332863at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15032">
        <property type="entry name" value="N-ACYL-PHOSPHATIDYLETHANOLAMINE-HYDROLYZING PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15032:SF4">
        <property type="entry name" value="N-ACYL-PHOSPHATIDYLETHANOLAMINE-HYDROLYZING PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="1">
        <location>
            <begin position="170"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="419" mass="49275" checksum="BCE71A5E1F07643F" modified="2017-02-15" version="1">MKKLINTFLPYYIHNNNLTTNLTFKKKISFFFFYVDRYIYSPLINSLLKNKNAQEKNIIKKVYTKKIFDILGLKNNYNKKKNENVENINDIYKKYTKYTKCSKEAIDKNSNNTNDINYKNFYNNEEMNAIWPDRIFYVTPLEVKKKIENEKFNVIYIGHMSILVQIKNFNILIDPVLSSRIGFFNILGVKRTIKAGISFENLPSIDFVLLSNNRFDIMDKNTLKKIILRDNSIVIGGMNIRRYLFKRNFPVVYPLNWFNKLTFENISFYYLPSLTNSHRYFIDKNIYLPGSFLIHNSTNNSSIFYSGHSGYSNHFLQIKSYVNTILKNDRIDLSILPIGIYKPSSLYNHFHMSPKQALQSHFDLNSKKSLGIGSDVFCLGGEEYNEATNELQNILNIYEKEKKKKIDFITLQPGQNIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTA3</accession>
    <name>A0A1J1GTA3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00287600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528487.1">
        <property type="nucleotide sequence ID" value="XM_028671879.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTA3"/>
    <dbReference type="GeneID" id="39731409"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00287600"/>
    <dbReference type="OMA" id="SIQLYSM"/>
    <dbReference type="OrthoDB" id="369514at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="220" mass="26003" checksum="DC6E04B2223DA490" modified="2017-02-15" version="1">MNIQKITTFCFLISYLVFCHIIWNGCYNIYSTSEDEMYNILYSKKKEGISLKVDTKKNIKLKDIKNLYMKSTPCPVLPRPFKSIFHLNWFRKSSELIPISIQLYSMFEEKNNFLGFILLCSAIFTIIEWVYIAYLACVLLWDGVIKPLFKILYILISTYMIIRFVVILLPYTKSYISQENYNYISSFILNFYNLITKISKELGNLMNKVIQESVVINKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTV5</accession>
    <name>A0A1J1GTV5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 10">6-phosphogluconate dehydrogenase, decarboxylating</fullName>
            <ecNumber evidence="6 10">1.1.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00213900</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>6-phospho-D-gluconate + NADP(+) = D-ribulose 5-phosphate + CO2 + NADPH</text>
            <dbReference type="Rhea" id="RHEA:10116"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="1.1.1.44"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 6 10">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 3/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6 10">Belongs to the 6-phosphogluconate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.44" evidence="6 10"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527557.1">
        <property type="nucleotide sequence ID" value="XM_028670845.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTV5"/>
    <dbReference type="GeneID" id="39730666"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00213900"/>
    <dbReference type="OMA" id="CVTHVGP"/>
    <dbReference type="OrthoDB" id="434986at2759"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004616">
        <property type="term" value="F:phosphogluconate dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019521">
        <property type="term" value="P:D-gluconate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000002">
        <property type="entry name" value="6-phosphogluconate dehydrogenase, decarboxylating"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.320:FF:000001">
        <property type="entry name" value="6-phosphogluconate dehydrogenase, decarboxylating"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000007">
        <property type="entry name" value="6-phosphogluconate dehydrogenase, decarboxylating"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.320">
        <property type="entry name" value="6-Phosphogluconate Dehydrogenase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006114">
        <property type="entry name" value="6PGDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006113">
        <property type="entry name" value="6PGDH_Gnd/GntZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006183">
        <property type="entry name" value="Pgluconate_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00873">
        <property type="entry name" value="gnd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006765">
        <property type="entry name" value="PRK09287.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11811">
        <property type="entry name" value="6-PHOSPHOGLUCONATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00393">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000109">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00076">
        <property type="entry name" value="6PGDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01350">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0311">Gluconate utilization</keyword>
    <keyword evidence="6 10" id="KW-0521">NADP</keyword>
    <keyword evidence="3 6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 6 10" id="KW-0570">Pentose shunt</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphogluconate dehydrogenase C-terminal" evidence="11">
        <location>
            <begin position="181"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="11"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="34"/>
            <end position="36"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="77"/>
            <end position="79"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="8">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="8">
        <location>
            <begin position="131"/>
            <end position="133"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="8">
        <location>
            <begin position="188"/>
            <end position="189"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="8">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="8">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="8">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="449"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="455"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG94742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="471" mass="53319" checksum="F752D9EE8BB3161E" modified="2017-02-15" version="1">MENKCDIGLIGLAVMGQNLSLNIASKGFKIGVYNRTYSRTEETMKRAKEEKLVVYGYKTLLELINNLKKPRIVILLIQAGPAVDENINNILSYFEEGDIIIDGGNEWYQNSERRINLCKEKKVEYLAMGVSGGEAGARYGCSFMPGGSKYAYDCVKNILEKCSAHVGDSPCVTYIGAGSSGNYVKMVHNGIEYGDMQLISESYIIMKNILNYDNRKLSEVFKKWNEGILNSYLIEITSKILEKKDELTDNYVIDMILDIAGAKGTGKWTMLESIERGIPCPTICAALDARNISTFKELRTKADLNFNSETKNCLCEDINTIENDILNALYCCKIISYTQGLFLLKQVSNEMNWELDLGEIARIWRGGCIIRAVFLDRITKAFKNDKKLELLLLDKDFSEEIKNKLPSLKKIVQLATQYSIPIPAFSASLAYFEMITSKNLPLNLVQAQRDYFGSHTYKRIDREGNYHTLWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTW0</accession>
    <name>A0A1J1GTW0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ubiquitin-conjugating enzyme E2, putative</fullName>
            <ecNumber evidence="8">6.3.2.19</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">UBC</name>
        <name evidence="8" type="ORF">PGAL8A_00317900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.19" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528774.1">
        <property type="nucleotide sequence ID" value="XM_028672196.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTW0"/>
    <dbReference type="GeneID" id="39731712"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00317900"/>
    <dbReference type="OMA" id="VHFTTRI"/>
    <dbReference type="OrthoDB" id="7851174at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd23792">
        <property type="entry name" value="UBCc_UBE2D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000010">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2-16 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="7">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="5">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="147" mass="16565" checksum="38250CEA8481B085" modified="2017-02-15" version="1">MALKRITKELQDLNKDPPTNCSAGPIGDDLFFWQATIMGPGDSPYENGVYFLNIKFPPDYPFKPPKIIFTTKIYHPNINTAGAICLDILKDQWSPALTISKVLLSISSLLTDPNPDDPLVPEIAHVYKTDRTKYHQTAKAWTQKYAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTZ2</accession>
    <name>A0A1J1GTZ2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00217900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527597.1">
        <property type="nucleotide sequence ID" value="XM_028670890.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTZ2"/>
    <dbReference type="GeneID" id="39730706"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00217900"/>
    <dbReference type="OMA" id="YFPSKNY"/>
    <dbReference type="OrthoDB" id="377210at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="271"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1149"/>
            <end position="1168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1150"/>
            <end position="1168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1168" mass="140258" checksum="0818FDDEE7450164" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU29</accession>
    <name>A0A1J1GU29_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00295200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528555.1">
        <property type="nucleotide sequence ID" value="XM_028671953.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731485"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00295200"/>
    <dbReference type="OMA" id="NNCICEL"/>
    <dbReference type="OrthoDB" id="372753at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031032">
        <property type="term" value="P:actomyosin structure organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23280">
        <property type="entry name" value="4.1 G PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23280:SF21">
        <property type="entry name" value="PROTEIN 4.1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="319"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1577"/>
            <end position="1602"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1614"/>
            <end position="1637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="607"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="359"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="609"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="644"/>
            <end position="666"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1679" mass="202847" checksum="94D9A63398733D42" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU44</accession>
    <name>A0A1J1GU44_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nascent polypeptide-associated complex subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00297500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Part of the nascent polypeptide-associated complex (NAC).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the NAC-beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528571.1">
        <property type="nucleotide sequence ID" value="XM_028671971.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU44"/>
    <dbReference type="GeneID" id="39731508"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00297500"/>
    <dbReference type="OMA" id="HAENKHL"/>
    <dbReference type="OrthoDB" id="8033832at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.30">
        <property type="entry name" value="Nascent polypeptide-associated complex domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039370">
        <property type="entry name" value="BTF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038187">
        <property type="entry name" value="NAC_A/B_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002715">
        <property type="entry name" value="Nas_poly-pep-assoc_cplx_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10351">
        <property type="entry name" value="TRANSCRIPTION FACTOR BTF3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01849">
        <property type="entry name" value="NAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01407">
        <property type="entry name" value="NAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51151">
        <property type="entry name" value="NAC_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="NAC-A/B" evidence="3">
        <location>
            <begin position="44"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="168" mass="19094" checksum="DD785E0AEEB2E8E9" modified="2017-02-15" version="1">MEKISPEILAARAKLKEKMGGNQRQIGGKGSARRKIKKVHKNTISNEKKINLILKKIGASYFGDVDEISVYKTDDTYLEFKKPKLSASLQSNTYIVTGKFTEQKIDINKIFEGLKGNKNLDVNLLEKIKNDPNIKNILNKENDLKKENDGVEIPDLVENFEEVSKEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUC0</accession>
    <name>A0A1J1GUC0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Kinesin-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00310900</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528705.1">
        <property type="nucleotide sequence ID" value="XM_028672120.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731642"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00310900"/>
    <dbReference type="OMA" id="PPGRNIE"/>
    <dbReference type="OrthoDB" id="21525at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00106">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968">
        <property type="entry name" value="CENTROMERE PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968:SF36">
        <property type="entry name" value="KINESIN HEAVY CHAIN ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0493">Microtubule</keyword>
    <keyword evidence="5 6" id="KW-0505">Motor protein</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="9">
        <location>
            <begin position="27"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="758"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1101"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1195"/>
            <end position="1316"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="140"/>
            <end position="147"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG95897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1481" mass="172299" checksum="D6B2B76575C163A0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUF3</accession>
    <name>A0A1J1GUF3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">NOL1/NOP2/Sun domain family member 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00337900</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a cytidine in rRNA + S-adenosyl-L-methionine = a 5-methylcytidine in rRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:61484"/>
            <dbReference type="Rhea" id="RHEA-COMP:15836"/>
            <dbReference type="Rhea" id="RHEA-COMP:15837"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74483"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528966.1">
        <property type="nucleotide sequence ID" value="XM_028672411.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUF3"/>
    <dbReference type="GeneID" id="39731909"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00337900"/>
    <dbReference type="OrthoDB" id="427002at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031167">
        <property type="term" value="P:rRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049560">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22808:SF3">
        <property type="entry name" value="5-METHYLCYTOSINE RRNA METHYLTRANSFERASE NSUN4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22808">
        <property type="entry name" value="NCL1 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 11" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="SAM-dependent MTase RsmB/NOP-type" evidence="12">
        <location>
            <begin position="88"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="11">
        <location>
            <position position="366"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00042050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG96161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="522" mass="62034" checksum="879C955B3CA7512B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUG6</accession>
    <name>A0A1J1GUG6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Trafficking protein particle complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TRAPPC5</name>
        <name evidence="8" type="ORF">PGAL8A_00309500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Part of the multisubunit TRAPP (transport protein particle) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Golgi apparatus</location>
            <location evidence="7">cis-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the TRAPP small subunits family. BET3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528691.1">
        <property type="nucleotide sequence ID" value="XM_028672105.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUG6"/>
    <dbReference type="GeneID" id="39731628"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00309500"/>
    <dbReference type="OMA" id="YMVKFDD"/>
    <dbReference type="OrthoDB" id="10254842at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990070">
        <property type="term" value="C:TRAPPI protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990071">
        <property type="term" value="C:TRAPPII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990072">
        <property type="term" value="C:TRAPPIII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14943">
        <property type="entry name" value="TRAPPC5_Trs31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.20">
        <property type="entry name" value="Trafficking protein particle complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016696">
        <property type="entry name" value="TRAPP-I_su5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007194">
        <property type="entry name" value="TRAPP_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20902">
        <property type="entry name" value="41-2 PROTEIN ANTIGEN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20902:SF0">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04051">
        <property type="entry name" value="TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017479">
        <property type="entry name" value="TRAPP_I_complex_Trs31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="Ligand-binding domain in the NO signalling and Golgi transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 7" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="6 7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR017479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="184" mass="21571" checksum="A55DB86391722CEC" modified="2017-02-15" version="1">MDKNKSSIEKELNKGKQDVSLSAFSFLFSEVVQYCLYKSKRGYRIEDCLHEMGLRVGYKLNEYLTYKNKMKRSINIVNMLTFISKYVWKYLFQHSSDLLKSQDSIYEYMICDKNILLNKFISIPKDYGNINCASFAAGIVEGLLCSSEFQAEVTAHTIYESDQNYNTTIFIKFYPEVVEREKNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUL5</accession>
    <name>A0A1J1GUL5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00239700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527813.1">
        <property type="nucleotide sequence ID" value="XM_028671130.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUL5"/>
    <dbReference type="GeneID" id="39730925"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00239700"/>
    <dbReference type="OMA" id="YFYHIIE"/>
    <dbReference type="OrthoDB" id="360388at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="865" mass="103149" checksum="E57922374A6FA11C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUP2</accession>
    <name>A0A1J1GUP2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">CLK3</name>
        <name evidence="11" type="ORF">PGAL8A_00341500</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529002.1">
        <property type="nucleotide sequence ID" value="XM_028672451.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUP2"/>
    <dbReference type="GeneID" id="39731945"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00341500"/>
    <dbReference type="OrthoDB" id="3967at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14135">
        <property type="entry name" value="STKc_PRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000440">
        <property type="entry name" value="CMGC/DYRK/PRP4 protein kinase, variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000078">
        <property type="entry name" value="Serine/threonine-protein kinase PRP4 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050494">
        <property type="entry name" value="Ser_Thr_dual-spec_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044092">
        <property type="entry name" value="STKc_PRP4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058:SF103">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE PRP4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="382"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="142"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="80"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="103"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="156"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="411"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG96197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="716" mass="83293" checksum="76CB25FE57AC6A42" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV04</accession>
    <name>A0A1J1GV04_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00328300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000056">
        <property type="protein sequence ID" value="CRG96070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528875.1">
        <property type="nucleotide sequence ID" value="XM_028672309.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV04"/>
    <dbReference type="GeneID" id="39731813"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00328300"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="323" mass="38662" checksum="CEF96E2A062C6296" modified="2017-02-15" version="1">MALLYNEGCENFEGDSAMCRMNICSIKQNKFDLSYCYLAEELVKVYHPLNNDSNVISRNIFKYERYGPYRHSRIIILSKDDQDGIVFLYEYNKLSYSYPTKTFLCRLRNINQTIALCESLDIYYIDNKLSFSSYDVINEKNDLPLKHLKNPNHKIIKSKYKDLFIKEHSCHHIKTRYISHRSCMYAICEKKNEDYMLCSDASYSGKLMFLDYYNRMNKKFIYLPESCLTRDSNFACNAYFCEINAKDKFFPCEHKEISAIKDIMPYSKRSEVMPIKQQIVHHEDNLSASALFAMTLMPFLILFVFFWCYIYKNFKKRRRRKIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVB4</accession>
    <name>A0A1J1GVB4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">PPM2</name>
        <name evidence="15" type="ORF">PGAL8A_00366200</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529242.1">
        <property type="nucleotide sequence ID" value="XM_028672717.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVB4"/>
    <dbReference type="GeneID" id="39732192"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00366200"/>
    <dbReference type="OMA" id="FPEVTCV"/>
    <dbReference type="OrthoDB" id="10264738at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF803">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="14">
        <location>
            <begin position="26"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="188"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="293"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="721"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="199"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="230"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="262"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="731"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="750"/>
            <end position="766"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG96437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="831" mass="95096" checksum="A1AFCDFE5A98859B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVM0</accession>
    <name>A0A1J1GVM0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetylgalactosaminide beta-1,3-galactosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.122</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PGAL8A_00009700</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.122" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528141.1">
        <property type="nucleotide sequence ID" value="XM_028671494.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVM0"/>
    <dbReference type="GeneID" id="39728619"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00009700"/>
    <dbReference type="OrthoDB" id="421979at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016263">
        <property type="term" value="F:glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026050">
        <property type="entry name" value="C1GALT1/C1GALT1_chp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003378">
        <property type="entry name" value="Fringe-like_glycosylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033">
        <property type="entry name" value="BETA1,3-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02434">
        <property type="entry name" value="Fringe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012791743" description="N-acetylgalactosaminide beta-1,3-galactosyltransferase" evidence="14">
        <location>
            <begin position="19"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="domain" description="Fringe-like glycosyltransferase" evidence="15">
        <location>
            <begin position="668"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="330"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="900"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="927"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="994"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="142"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="900"/>
            <end position="912"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="CRG95330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1030" mass="124327" checksum="9D6976954C209403" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVT3</accession>
    <name>A0A1J1GVT3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mitochondrial ribosomal protein S16, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00415300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529378.1">
        <property type="nucleotide sequence ID" value="XM_028672869.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVT3"/>
    <dbReference type="GeneID" id="39732684"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00415300"/>
    <dbReference type="OMA" id="PRIRCQI"/>
    <dbReference type="OrthoDB" id="407221at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1320.10:FF:000011">
        <property type="entry name" value="Mitochondrial ribosomal protein S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000307">
        <property type="entry name" value="Ribosomal_bS16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023803">
        <property type="entry name" value="Ribosomal_bS16_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12919">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12919:SF20">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN BS16M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00886">
        <property type="entry name" value="Ribosomal_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54565">
        <property type="entry name" value="Ribosomal protein S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="213" mass="26034" checksum="6D400E47D257542E" modified="2017-02-15" version="1">MIRRLFLPYFSKDKGPPRIRCQINGVKRKRFYKIVVANQKDKKNGKHIEVLGTYVNKNNIREKLNRYNIADSNNDYYYNNVENIKEIRLRFNRVKFWLAANCNFSDHMKYVLSLCKIIPQYPIKYSRRCSDKYYYKYNEIINKHKLIQAEKINNFLKTDLNIQYLNNFNESSNERKKEDDYLYTPEELTYLKKLSKNRNLDFEHTDKIRKIIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVX5</accession>
    <name>A0A1J1GVX5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L35ae, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00370100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529281.1">
        <property type="nucleotide sequence ID" value="XM_028672761.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVX5"/>
    <dbReference type="GeneID" id="39732231"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00370100"/>
    <dbReference type="OMA" id="YRTNKHH"/>
    <dbReference type="OrthoDB" id="504467at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.190:FF:000002">
        <property type="entry name" value="60S ribosomal protein L35ae, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.190">
        <property type="entry name" value="translation elongation factor selb, chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00573">
        <property type="entry name" value="Ribosomal_eL33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001780">
        <property type="entry name" value="Ribosomal_eL33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038661">
        <property type="entry name" value="Ribosomal_eL33_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10902">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L35A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01247">
        <property type="entry name" value="Ribosomal_L35Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="136" mass="15894" checksum="E436F4DD0ED127B3" modified="2017-02-15" version="1">MEENKNKEKTSIKKKNKVKKQLKNKKSSKKTQAVRLYEKGVILGYKRSQRNQDPNFTLIAIKNVNTKQHAQFYVGKRVAYVYRTNKHHNGVKIKCIWGKVCRTHGNNGVIRAKFRTHIPPKAFGDRVRILMYPSNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVX6</accession>
    <name>A0A1J1GVX6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00363800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529219.1">
        <property type="nucleotide sequence ID" value="XM_028672692.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVX6"/>
    <dbReference type="GeneID" id="39732168"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00363800"/>
    <dbReference type="OMA" id="CTSIHVN"/>
    <dbReference type="OrthoDB" id="387422at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="658"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="604"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="158"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="605"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="676" mass="78343" checksum="FEF88214766C07FC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWB9</accession>
    <name>A0A1J1GWB9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">B box-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00007500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528120.1">
        <property type="nucleotide sequence ID" value="XM_028671471.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728597"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00007500"/>
    <dbReference type="OrthoDB" id="387094at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19757">
        <property type="entry name" value="Bbox1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000315">
        <property type="entry name" value="Znf_B-box"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57845">
        <property type="entry name" value="B-box zinc-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50119">
        <property type="entry name" value="ZF_BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="B box-type" evidence="4">
        <location>
            <begin position="143"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="261"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="683"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1139"/>
            <end position="1173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1816"/>
            <end position="1836"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="432"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="262"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="273"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="715"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1148"/>
            <end position="1158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1160"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1820"/>
            <end position="1833"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1861" mass="218824" checksum="C15C4469EAD3E4AB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWM0</accession>
    <name>A0A1J1GWM0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00451700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529740.1">
        <property type="nucleotide sequence ID" value="XM_028673270.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733050"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00451700"/>
    <dbReference type="OMA" id="NYEQKNY"/>
    <dbReference type="OrthoDB" id="1668230at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957:SF27">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="74"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="3">
        <location>
            <begin position="381"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="896"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1230"/>
            <end position="1257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="912"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="927"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1247"/>
            <end position="1257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1596" mass="192977" checksum="4F3BFA99C4C05311" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWR8</accession>
    <name>A0A1J1GWR8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Splicing factor 3B subunit 3, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">SF3B3</name>
        <name evidence="11" type="ORF">PGAL8A_00456500</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the RSE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529788.1">
        <property type="nucleotide sequence ID" value="XM_028673325.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWR8"/>
    <dbReference type="GeneID" id="39733098"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00456500"/>
    <dbReference type="OMA" id="PRATGHW"/>
    <dbReference type="OrthoDB" id="436637at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000031">
        <property type="entry name" value="Splicing factor 3b subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000640">
        <property type="entry name" value="Splicing factor 3B subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018846">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058543">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050358">
        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004871">
        <property type="entry name" value="RSE1/DDB1/CPSF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10433">
        <property type="entry name" value="Beta-prop_RSE1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23726">
        <property type="entry name" value="Beta-prop_RSE1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03178">
        <property type="entry name" value="CPSF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 first beta-propeller" evidence="9">
        <location>
            <begin position="14"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 second beta-propeller" evidence="10">
        <location>
            <begin position="441"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 C-terminal" evidence="8">
        <location>
            <begin position="918"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="839"/>
            <end position="858"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF23726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG96985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1266" mass="143839" checksum="8ACCEC8159383E18" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWT3</accession>
    <name>A0A1J1GWT3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Dynein-associated protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00297700</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynein intermediate chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528573.1">
        <property type="nucleotide sequence ID" value="XM_028671973.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWT3"/>
    <dbReference type="GeneID" id="39731510"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00297700"/>
    <dbReference type="OMA" id="WDFFYRQ"/>
    <dbReference type="OrthoDB" id="366230at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036157">
        <property type="term" value="C:outer dynein arm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045504">
        <property type="term" value="F:dynein heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045503">
        <property type="term" value="F:dynein light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003341">
        <property type="term" value="P:cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036158">
        <property type="term" value="P:outer dynein arm assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050687">
        <property type="entry name" value="Dynein_IC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442:SF7">
        <property type="entry name" value="DYNEIN AXONEMAL INTERMEDIATE CHAIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442">
        <property type="entry name" value="DYNEIN INTERMEDIATE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0243">Dynein</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="12">
        <location>
            <begin position="218"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG95765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="602" mass="71146" checksum="D14EE943A7D3BC9C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWX2</accession>
    <name>A0A1J1GWX2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00434100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529563.1">
        <property type="nucleotide sequence ID" value="XM_028673073.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732873"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00434100"/>
    <dbReference type="OMA" id="IKGCIKI"/>
    <dbReference type="OrthoDB" id="392610at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="971"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1037"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1307"/>
            <end position="1326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1368"/>
            <end position="1385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2054" mass="247985" checksum="7BDE7D1C076AEF55" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXB9</accession>
    <name>A0A1J1GXB9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 20">DNA-directed RNA polymerase subunit beta</fullName>
            <ecNumber evidence="5 20">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="27" type="ORF">PGAL8A_00315400</name>
    </gene>
    <organism evidence="27 28">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="27" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="27">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 20">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18 20">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="17">In plastids the minimal PEP RNA polymerase catalytic core is composed of four subunits: alpha, beta, beta', and beta''. When a (nuclear-encoded) sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Plastid</location>
            <location evidence="3">Apicoplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 19">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="27">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="5 20"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528749.1">
        <property type="nucleotide sequence ID" value="XM_028672169.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731687"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00315400"/>
    <dbReference type="OMA" id="LAYCSWC"/>
    <dbReference type="OrthoDB" id="10248617at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020011">
        <property type="term" value="C:apicoplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.270.10:FF:000006">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.270.10:FF:000011">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1070.20:FF:000002">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1100.10:FF:000013">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1100.10:FF:000021">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1110.10:FF:000011">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1070.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="entry name" value="DNA-directed RNA polymerase, subunit 2, domain 6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1800.10">
        <property type="entry name" value="RNA polymerase alpha subunit dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="entry name" value="RNA polymerase Rpb2, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007646">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007175">
        <property type="entry name" value="PRK09606.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04566">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0933">Apicoplast</keyword>
    <keyword evidence="7 20 27" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 20" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-0934">Plastid</keyword>
    <keyword evidence="28" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15 20" id="KW-0804">Transcription</keyword>
    <keyword evidence="9 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="13" id="KW-0862">Zinc</keyword>
    <keyword evidence="12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RNA polymerase beta subunit protrusion" evidence="24">
        <location>
            <begin position="196"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="23">
        <location>
            <begin position="345"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="25">
        <location>
            <begin position="624"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="26">
        <location>
            <begin position="726"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase subunit 2 hybrid-binding" evidence="21">
        <location>
            <begin position="855"/>
            <end position="1274"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="22">
        <location>
            <begin position="1276"/>
            <end position="1361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00026088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="RuleBase" id="RU363031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF04561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF04563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="Pfam" id="PF04566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="EMBL" id="CRG95941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1364" mass="156752" checksum="641E304A3AC0F290" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXC0</accession>
    <name>A0A1J1GXC0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00479800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530022.1">
        <property type="nucleotide sequence ID" value="XM_028673584.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733331"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00479800"/>
    <dbReference type="OMA" id="KYICIIS"/>
    <dbReference type="OrthoDB" id="378452at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016035">
        <property type="term" value="C:zeta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030559">
        <property type="entry name" value="PolZ_Rev3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45812">
        <property type="entry name" value="DNA POLYMERASE ZETA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45812:SF1">
        <property type="entry name" value="DNA POLYMERASE ZETA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1383"/>
            <end position="1410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1045"/>
            <end position="1107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1264"/>
            <end position="1313"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="112"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="563"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1049"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1076"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1096"/>
            <end position="1107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1741" mass="212071" checksum="A497D891C068DB3F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXH7</accession>
    <name>A0A1J1GXH7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">26S proteasome regulatory subunit p55, putative</fullName>
            <ecNumber evidence="4">3.4.25.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPN5</name>
        <name evidence="4" type="ORF">PGAL8A_00477000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit p55 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.25.1" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529994.1">
        <property type="nucleotide sequence ID" value="XM_028673553.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXH7"/>
    <dbReference type="GeneID" id="39733303"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00477000"/>
    <dbReference type="OMA" id="CKIDRIK"/>
    <dbReference type="OrthoDB" id="268763at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008541">
        <property type="term" value="C:proteasome regulatory particle, lid subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000070">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054559">
        <property type="entry name" value="PSMD12-CSN4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040134">
        <property type="entry name" value="PSMD12/CSN4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040896">
        <property type="entry name" value="RPN5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10855:SF1">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10855">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22241">
        <property type="entry name" value="PSMD12-CSN4_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18098">
        <property type="entry name" value="RPN5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 4" id="KW-0647">Proteasome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="3">
        <location>
            <begin position="241"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="468" mass="55879" checksum="3849F9EA21C6A4E3" modified="2017-02-15" version="1">MEEDNTAKIIGSHDNLLTDPRIAQDFSNETDELLKKAEKYYKVGDFEIILEDLITLEKRCRQSFDGVSTSKICCFILNKYKLNNNYKKVSEYLIFFNKKRGQLKRTIIDMINLCKSWINDIEDKEEKLNLINTLCTISEGKIFVEVERSEIIKILSKIKEDDGNIEEAANILQDVQVETFISMNKREKTEYILEQMRLVLLRKDYIRCHVISRKINPTLLNNEEFYDLKLKYFMYMIEYYIYEESYSDVAKCYEERFNTDFILKDPNLWVEELKCYILFLILSPFDEQQSKFLNLIKIEKKKLKEIPIFEQLVKDFINQDLIHWPLQYQDELLQFYVFNDTKFMGGENRWNLFKKKVMHHNIHVISNCYNKISLNRLSELLNASVEETENLLSELVSNKFLIAKIDRLYGIIKFGQKNNPENLLNNWSSQINQILDLLEESSHLIQKERMLHEAKLKRMQLENKNLTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXU3</accession>
    <name>A0A1J1GXU3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL3m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00466100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529883.1">
        <property type="nucleotide sequence ID" value="XM_028673430.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXU3"/>
    <dbReference type="GeneID" id="39733194"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00466100"/>
    <dbReference type="OMA" id="IGIYPMW"/>
    <dbReference type="OrthoDB" id="274683at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000597">
        <property type="entry name" value="Ribosomal_uL3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019927">
        <property type="entry name" value="Ribosomal_uL3_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03625">
        <property type="entry name" value="L3_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11229">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11229:SF8">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL3M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00297">
        <property type="entry name" value="Ribosomal_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="333" mass="39146" checksum="2901416158ADA305" modified="2017-02-15" version="1">MNNYLRKKDFIFSLFFIIKEKRTFYSSKWIRRLQLLNEKYNYKIENEEEIEYEEKKEDDQIEKVYPLWNSRRTGLLGYKVGCMSIWDVWGVKHAVTVVKINNCFVLNQKNISRNGYEALEIGIGNMNVIKQSKNNIGNYIKRKLGFIHKIKEFKCTSDCFLPVQHRFSARHFSPGQNLFISSSIKNKGFCGAMKRWNFSGKNKSHGTESKAHRSLGSVSMGKTINIVFRNKKMNTHIGDKNLVKCSNNKLFRINSLKNLLFIKGPIGGYKNKVIKISDAKGRSFNKFKNKIFLYYPTFIYKKNKKYKNVIDMPHSIEDPFLYNEIPLYEPTNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXW6</accession>
    <name>A0A1J1GXW6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thymidylate kinase</fullName>
            <ecNumber evidence="3">2.7.4.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00472300</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; dTTP biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the thymidylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.9" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529945.1">
        <property type="nucleotide sequence ID" value="XM_028673498.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXW6"/>
    <dbReference type="GeneID" id="39733256"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00472300"/>
    <dbReference type="OMA" id="YWHQFDA"/>
    <dbReference type="OrthoDB" id="425602at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004798">
        <property type="term" value="F:dTMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006233">
        <property type="term" value="P:dTDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006227">
        <property type="term" value="P:dUDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01672">
        <property type="entry name" value="TMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001633">
        <property type="entry name" value="Thymidylate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00165">
        <property type="entry name" value="Thymidylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039430">
        <property type="entry name" value="Thymidylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018095">
        <property type="entry name" value="Thymidylate_kin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018094">
        <property type="entry name" value="Thymidylate_kinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00041">
        <property type="entry name" value="DTMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10344">
        <property type="entry name" value="THYMIDYLATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10344:SF1">
        <property type="entry name" value="THYMIDYLATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02223">
        <property type="entry name" value="Thymidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01331">
        <property type="entry name" value="THYMIDYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylate kinase-like" evidence="10">
        <location>
            <begin position="13"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG97142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="211" mass="24914" checksum="397CAE3824313408" modified="2017-02-15" version="1">MSDSKKIGKFIVLEGLDRSGKSTQSKLLVEYLKNENIEVKHLYFPNRETPIGQIIAKYLKMENSMPNETIHLLFSANRWELMNEIKSLLLRGVWVVCDRYAYSGVAYSAGALNLTKNWCMNPDQGLIKPDIVFYLDVPPNYAQNRSEYGEEIYEKIDVQKRIYETYKHFSKEDYWTNIDATKNIDEIHKDILKYIKKLKIVKEQHFKFLWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY01</accession>
    <name>A0A1J1GY01_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">AAR2 protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00501500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAR2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530243.1">
        <property type="nucleotide sequence ID" value="XM_028673829.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY01"/>
    <dbReference type="GeneID" id="39733548"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00501500"/>
    <dbReference type="OMA" id="EFKMNEM"/>
    <dbReference type="OrthoDB" id="201752at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000244">
        <property type="term" value="P:spliceosomal tri-snRNP complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13778">
        <property type="entry name" value="Aar2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13777">
        <property type="entry name" value="Aar2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.550">
        <property type="entry name" value="Aar2, C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007946">
        <property type="entry name" value="AAR2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033648">
        <property type="entry name" value="AAR2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038514">
        <property type="entry name" value="AAR2_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033647">
        <property type="entry name" value="Aar2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12689">
        <property type="entry name" value="A1 CISTRON SPLICING FACTOR AAR2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12689:SF4">
        <property type="entry name" value="PROTEIN AAR2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05282">
        <property type="entry name" value="AAR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20981">
        <property type="entry name" value="AAR2_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAR2 N-terminal" evidence="5">
        <location>
            <begin position="123"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="AAR2 C-terminal" evidence="4">
        <location>
            <begin position="372"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="319"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="57"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="324"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF20981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="549" mass="66485" checksum="A15670E4619F1044" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY33</accession>
    <name>A0A1J1GY33_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00504100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530269.1">
        <property type="nucleotide sequence ID" value="XM_028673858.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY33"/>
    <dbReference type="GeneID" id="39733574"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00504100"/>
    <dbReference type="OMA" id="FNFFCYH"/>
    <dbReference type="OrthoDB" id="371890at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="239"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="413"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="458"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="499"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="639" mass="77547" checksum="87D7159C821C18D3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY88</accession>
    <name>A0A1J1GY88_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="5">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00509700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="5">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530325.1">
        <property type="nucleotide sequence ID" value="XM_028673920.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY88"/>
    <dbReference type="GeneID" id="39733630"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00509700"/>
    <dbReference type="OMA" id="YTPFSEK"/>
    <dbReference type="OrthoDB" id="10256233at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="34"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="138"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="589"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="323"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="332"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG97524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="789" mass="95029" checksum="2AE441EDAB43A7EC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY92</accession>
    <name>A0A1J1GY92_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RED-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00502900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530257.1">
        <property type="nucleotide sequence ID" value="XM_028673845.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY92"/>
    <dbReference type="GeneID" id="39733562"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00502900"/>
    <dbReference type="OrthoDB" id="3366823at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039896">
        <property type="entry name" value="Red-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012916">
        <property type="entry name" value="RED_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12765">
        <property type="entry name" value="RED PROTEIN IK FACTOR CYTOKINE IK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07808">
        <property type="entry name" value="RED_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RED-like N-terminal" evidence="5">
        <location>
            <begin position="38"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="272"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="48"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="387" mass="47020" checksum="018E09631ABC5C1D" modified="2017-02-15" version="1">MSNELTNNDFRLIFDKYEKEKKEKEIKLLLKEEKKLKRKQKYLVKKKKNEEKSEQKYRDRAEERRKGIIKDIKDSTVLYNNVNNTIDESKYMGGDIEHTHLVKGLDFLLLNKIRNKLINKISLEKEKVKSNKIKYPNKIPEFLNNESKYIYKYFFLYEHPHHINFKKKIENIYNNIMNNMKFKNFNKNIHYFNYKYNVDMNVDKNDIPIKYIYNVDNIKTNYTYYIKDSFLNEIGICFKWHMENKKKKKNERLSKRPLTGFLKEEQICDEYIDIFKNDNENFNKNINKIENNNSIMNNNYDYNNINKVKDVSIHINDDEVKNKDDINKENLSEITINNTEKNINLFSSENNYKTNNQNLNEKKNSLNKNVFSDTYEECYPGYNKYIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYA8</accession>
    <name>A0A1J1GYA8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Exported protein 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">EXP1</name>
        <name evidence="4" type="ORF">PGAL8A_00348200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529069.1">
        <property type="nucleotide sequence ID" value="XM_028672525.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYA8"/>
    <dbReference type="GeneID" id="39732012"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00348200"/>
    <dbReference type="OMA" id="FCAILCD"/>
    <dbReference type="OrthoDB" id="387289at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06589">
        <property type="entry name" value="CRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012633732" evidence="3">
        <location>
            <begin position="23"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="133" mass="14633" checksum="18DE9BE3CB0C5A0C" modified="2017-02-15" version="1">MKRLSIIFFVFFFIFFNKSLEGKIKTEGGNAIKKRSPKKPEPLVDVQELLADMIKKDEELVQITKSKAGYKLATQILSATLGVVSAALIGGIGLVMFNANRGRHPFKIGPSEPKNEDVDSSEEGNDTNEETSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYJ9</accession>
    <name>A0A1J1GYJ9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Oxysterol-binding protein-related protein 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00359200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the OSBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529173.1">
        <property type="nucleotide sequence ID" value="XM_028672640.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYJ9"/>
    <dbReference type="GeneID" id="39732122"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00359200"/>
    <dbReference type="OrthoDB" id="1854502at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13293">
        <property type="entry name" value="PH_CpORP2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.120">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972:SF205">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01237">
        <property type="entry name" value="Oxysterol_BP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="5" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PH" evidence="7">
        <location>
            <begin position="52"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="19"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="397"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="890"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="19"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="397"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="890"/>
            <end position="907"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1236" mass="145579" checksum="76AE49E55D8FB2F4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYL4</accession>
    <name>A0A1J1GYL4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Calcium/calmodulin-dependent protein kinase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00332200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528912.1">
        <property type="nucleotide sequence ID" value="XM_028672351.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYL4"/>
    <dbReference type="GeneID" id="39731852"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00332200"/>
    <dbReference type="OMA" id="QNECKRE"/>
    <dbReference type="OrthoDB" id="5794026at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050205">
        <property type="entry name" value="CDPK_Ser/Thr_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24349">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="195"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="127"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1150" mass="137907" checksum="3B0EBDD029B82444" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYM1</accession>
    <name>A0A1J1GYM1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00513800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530366.1">
        <property type="nucleotide sequence ID" value="XM_028673966.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYM1"/>
    <dbReference type="GeneID" id="39733671"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00513800"/>
    <dbReference type="OMA" id="FYSGYHK"/>
    <dbReference type="OrthoDB" id="389724at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056322">
        <property type="entry name" value="Microp_apicomplexa_21"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23535">
        <property type="entry name" value="Microp_apicomplexa_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="89" mass="10532" checksum="CF0A1EDD8F410743" modified="2017-02-15" version="1">MGFFYCGFHKPNRKNIKDKRAKILYVLGLFILPTVMTFIGGNYYILNFFIDTFKPIEVPREVDFEIIKSIYHNKKPKSKSSDYDENTNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYN9</accession>
    <name>A0A1J1GYN9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Bromodomain protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00493200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530155.1">
        <property type="nucleotide sequence ID" value="XM_028673731.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYN9"/>
    <dbReference type="GeneID" id="39733465"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00493200"/>
    <dbReference type="OMA" id="CNPNDAD"/>
    <dbReference type="OrthoDB" id="448960at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04369">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018359">
        <property type="entry name" value="Bromodomain_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24173">
        <property type="entry name" value="ANKYRIN REPEAT CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24173:SF74">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00633">
        <property type="entry name" value="BROMODOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3 5" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="90"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="123"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="156"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="7">
        <location>
            <begin position="343"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="458"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="494" mass="57756" checksum="4F5B77268EF7097C" modified="2017-02-15" version="1">MYEDFNTLPLIRSIREDEFDKVLEFLEKNYNEYKVKDGIINKKTEIVDKQTQATPLFYVTARKSDDESVEISKLLIEKYALCNPTTKDLMKQTCLFYAAREGHINLCNYLIEKGCNPNDSDNFGQTCLFYASREGKTECVQNLIKKGANPNLLDFNKQTCLFYACRDGRYDTVKCLLENGVNPSIKDSQRRTALTFAKGNGHQNIINLLKNANTLNRSFNESHTQSNNLNSLKRNSSCLYGQNYQNENNNNIANIMRDNNNINNTNKTLRKKYKLQYRPLEEEDPLLWLDAPLIKIKEFERKFPQLALWPKNTSVTNIELNNTNNAFNKQWYTSANQLIQSLSKYDGGHIFEKLVDPKKQNCPDYYDVIKNPMSFSCIKSKLKKGQYKSPTEFIKDVQLIFDNCNLYNTSNSLVAITGKNIETYFNNQLIVTGFNSFVTKEKRINELLKKVEEENIKWSEEQEREQKQEQKQEQEKEMEMEMEKNEEKIKLEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYP0</accession>
    <name>A0A1J1GYP0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00500300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530232.1">
        <property type="nucleotide sequence ID" value="XM_028673817.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYP0"/>
    <dbReference type="GeneID" id="39733536"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00500300"/>
    <dbReference type="OMA" id="HKGFCET"/>
    <dbReference type="OrthoDB" id="375359at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="176" mass="21350" checksum="DC1A7246A4B0FCAB" modified="2017-02-15" version="1">MSINKNSIFTILISGTVGWSLNKLYRKNELNIHGIKDNHDIIIVRQINIYDNKYNDNKLNIQNENELLKFVENFNKINKKYKGFCETSIFKNSSFSNFKNEHSDKSFNTYLIIDKWKTKNDFEKSKEEFKKLFLQKNDEYNEKMKDIYYKFEVYNNKYETTSAKNILQKIIYFFFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYS4</accession>
    <name>A0A1J1GYS4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ABM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00529300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530517.1">
        <property type="nucleotide sequence ID" value="XM_028674134.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYS4"/>
    <dbReference type="GeneID" id="39733826"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00529300"/>
    <dbReference type="OMA" id="YEFFPIF"/>
    <dbReference type="OrthoDB" id="360976at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="154" mass="18616" checksum="1541985144145D55" modified="2017-02-15" version="1">MIGKIFDNAFRIRTYNRLICFLIGGSFTYSLTNPDIDTVYEFFPIFKQNKYAYLTFLEINEKNDKIFEEKLKDLCRFYQKQQGYLYTKIIKRKNNINNLSKYIIVSTWLKSENYLLACNRLYGQILIKNIQKYTNYNSYLYRIVVDDSDYLPPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYY6</accession>
    <name>A0A1J1GYY6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00502200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530250.1">
        <property type="nucleotide sequence ID" value="XM_028673837.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYY6"/>
    <dbReference type="GeneID" id="39733555"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00502200"/>
    <dbReference type="OMA" id="KCTISTN"/>
    <dbReference type="OrthoDB" id="374158at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="134" mass="16234" checksum="228B13B9FE9A114C" modified="2017-02-15" version="1">MHNHFFNFFSKSLSSFKMFVEKKEKYRLYNFLNNKISTKIITGDKEKAELGIHKINKFDNILNNLKKDNQINQKTINICNIFNNYINISDINIYKEGNLKKILYFKWKARKSYKKRVLNLPSTKSRRRYAQKNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ66</accession>
    <name>A0A1J1GZ66_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00532700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530550.1">
        <property type="nucleotide sequence ID" value="XM_028674170.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ66"/>
    <dbReference type="GeneID" id="39733860"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00532700"/>
    <dbReference type="OrthoDB" id="385596at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="403"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="442" mass="52670" checksum="4D0E11EC93DE643D" modified="2017-02-15" version="1">MNIYLNSKYKKFRITLLILYFSLIKLNAIKINNKKKSELPHEYVEKSIPLNKVIPYFDEVMTIHQDKVLKKVSSGDNICIKSIKNHHSLNPSSEIKYKINSQEFLVETNHDGNIYNYTKKILTNLGFDLCNKILELFIPSNKHICEFHSFYNYFLYINYVKNEKIEKIKEELQKGKFIFIKLPEIFNLNLSVANFSENEYNIKSGILENNLIKIDVTDIMLNNICSNYDKEKESDNKKKIYNKSHNVNEEKNIRFAILTSHELSDIIIFSFKIININSIRNYKNMKNIVKLKKDIKNIYMEWEEWSPCYNSCENNFAYKCRYNKCIDDKNSFCDKNFHINFNECESTLCKEPLKDEDNKEIKKEIDFPSNIEKVIYDDEEMLRDNKDKKNVNFFMWLINDKKLSLGLLIFVIGIIILSCIYCYVNSSLNFHNDEEYYVSKYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZB4</accession>
    <name>A0A1J1GZB4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Apoptosis-related protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00422100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PDCD5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529445.1">
        <property type="nucleotide sequence ID" value="XM_028672942.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZB4"/>
    <dbReference type="GeneID" id="39732753"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00422100"/>
    <dbReference type="OMA" id="MQYEMQK"/>
    <dbReference type="OrthoDB" id="10252486at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.140">
        <property type="entry name" value="PDCD5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002836">
        <property type="entry name" value="PDCD5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036883">
        <property type="entry name" value="PDCD5-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10840">
        <property type="entry name" value="PROGRAMMED CELL DEATH PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10840:SF0">
        <property type="entry name" value="PROGRAMMED CELL DEATH PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01984">
        <property type="entry name" value="dsDNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015730">
        <property type="entry name" value="TFAR19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46950">
        <property type="entry name" value="Double-stranded DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="3"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="131" mass="15674" checksum="66EFA1343CAEDAEB" modified="2017-02-15" version="1">MNIEKAEVNSKLIELSKQNLENKTKKELELKQKHDELLEQRRIILKSLLTPEAHARLSRIAIVKEDKARKIEDIIIRNSQMGLLHKKIDDDQLIKIIEQISEKIYKKEPVIEIRRRKQFDDDDDFNEEDYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZH7</accession>
    <name>A0A1J1GZH7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TRAP-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00377500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000130">
        <property type="protein sequence ID" value="CRG97974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530773.1">
        <property type="nucleotide sequence ID" value="XM_028674417.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZH7"/>
    <dbReference type="GeneID" id="39732305"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00377500"/>
    <dbReference type="OMA" id="NEHEATQ"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="318" mass="37285" checksum="08F1D2C9C9467FA0" modified="2017-02-15" version="1">MNNDDKEETFHSDQNKNDKLTYEHQTYDNIDGGKQKINEETKEHGKQEISEETEEHGKHDKKMKNDDVKEEEIFHSDQNNNGTLTNKHQTDGNIDGEKQEISEETEEHGKQDNKMNNDDKEETFHSDQNKNDKLTYEQQSGDNMNGEKQEISEETEEHGKQDKKMKNDVDKEETFHSYQNKNDTLINEHHSGDNMNGGKQKINEETKEHGKQEIDKIIRENGKHDKKMNNDDDKEEEIFHFDQNNNDTVTNKYQTDGNIDGEKQEISEETEEHGKQDKKMKNDVDKEETFHSYQNKNDTLINEHHSGDNMNGGKQVKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZI1</accession>
    <name>A0A1J1GZI1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00428500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529509.1">
        <property type="nucleotide sequence ID" value="XM_028673014.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZI1"/>
    <dbReference type="GeneID" id="39732817"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00428500"/>
    <dbReference type="OrthoDB" id="378695at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="23"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="206" mass="24670" checksum="1551AC35D87F3CF6" modified="2017-02-15" version="1">MSKIVRERRKYRISNPYDESEKIAIKENKEKELKKKVKEKLESNNNENNIAENFIKIYNKYLEENEDIEKYKKENKEIEESKKKTVSRKKIKKLNYKLKKNSLIEKLIKKKAFIKANEVLSNSSNKNNRNFSINTNEEKYMKLIENQNNVLKEKSKINTKKNSNTKKKKNDIANQYDKIINSNSYLQNPLEYVKNILKDKKKDSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZM3</accession>
    <name>A0A1J1GZM3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Replication factor A protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00049700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530859.1">
        <property type="nucleotide sequence ID" value="XM_028674514.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZM3"/>
    <dbReference type="GeneID" id="39729022"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00049700"/>
    <dbReference type="OMA" id="NCVECII"/>
    <dbReference type="OrthoDB" id="368957at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG98062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="133" mass="15362" checksum="B05A83384C9F3BA2" modified="2017-02-15" version="1">MDDFDENNNVIEKNELNDSEICSYNKVGKLTSEKYLSELINEEIFFIGEIISLQDNIINLKSVNGNCVECIIKDRNFKTDSKYIGIKGIVSNNLKIIETRGIIPLEDINFEIVNEYINIYMENMNSEVFLSSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZP5</accession>
    <name>A0A1J1GZP5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Aspartate--tRNA ligase, putative</fullName>
            <ecNumber evidence="8">6.1.1.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00035800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.12" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530721.1">
        <property type="nucleotide sequence ID" value="XM_028674360.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZP5"/>
    <dbReference type="GeneID" id="39728882"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00035800"/>
    <dbReference type="OrthoDB" id="372395at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017101">
        <property type="term" value="C:aminoacyl-tRNA synthetase multienzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006422">
        <property type="term" value="P:aspartyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004523">
        <property type="entry name" value="Asp-tRNA_synthase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450:SF1">
        <property type="entry name" value="ASPARTATE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450">
        <property type="entry name" value="ASPARTYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="7">
        <location>
            <begin position="420"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="330"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="343"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="991" mass="118923" checksum="0286F1B8BE82121B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0B5</accession>
    <name>A0A1J1H0B5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00057500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530937.1">
        <property type="nucleotide sequence ID" value="XM_028674601.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729100"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00057500"/>
    <dbReference type="OrthoDB" id="376267at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="738"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="908"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1117"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1206"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1936"/>
            <end position="1968"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2417"/>
            <end position="2437"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="612"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="843"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1500"/>
            <end position="1561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="766"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1118"/>
            <end position="1136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1206"/>
            <end position="1221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1936"/>
            <end position="1947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1948"/>
            <end position="1957"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3301" mass="393945" checksum="EC5ED1563A5AEF64" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0H9</accession>
    <name>A0A1J1H0H9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00064300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028531001.1">
        <property type="nucleotide sequence ID" value="XM_028674672.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0H9"/>
    <dbReference type="GeneID" id="39729168"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00064300"/>
    <dbReference type="OrthoDB" id="372221at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="326" mass="38368" checksum="B4988A945A922172" modified="2017-02-15" version="1">MNKNIKNERKCDNEREIILLGFLNMECVYGKNWFSKKNEIKKDIEYKAVKLNQAFKHPSIFHENFEFLSADDYNYVKNNYIYSAILIFNPNLTNKNSNEEKENNKNSVNNSKKNVYMISNNKKSKENKSKIENIKIHENEKNTEECSNDSQLKEVNNETEQIKDNLDKKKEGIGVLVVTCKKMEKIKMKHILIKMLKKEIKVESTVLKCKDKISNYNIKNNEDNKSKSKLTEIKYLDKPDISLNINKPFDVKKNNFFNMTAYIYGSSNILANTSLVQREYCDDEWAEKLRRTKKEKAEINKTVSDNNKESRKETGLIRSFTSLFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H111</accession>
    <name>A0A1J1H111_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00057600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530938.1">
        <property type="nucleotide sequence ID" value="XM_028674602.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H111"/>
    <dbReference type="GeneID" id="39729101"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00057600"/>
    <dbReference type="OMA" id="HICADTN"/>
    <dbReference type="OrthoDB" id="369753at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="437" mass="52880" checksum="151A2B0EF083BBDE" modified="2017-02-15" version="1">MKYLKKRKLHNLKKISIRMKHGHFFYFIRELLRLKKLKKLYVKQCKKERELIQKVKKKKLKKKKKLYINDNIKRDAAKNKKKRKINKRLNDKAIKNNKKENKKKDKTERSNLKNNDKINKVNKIIIKKEKKKRDKNLIQNKLDSINHHKKGKERKKIVKNKQKIKDGNKKDKTEISEFKENIEINHMEKIKNDCKGNNSAEISSDLSNKIFRIQNSTKIFDINLMRNYTNENNLIKKPNNEHNVIELHHNKYNVKELHDNIKLIEKFDSKNKSINNNISKEMLEYFVSKCIDLKNFIVTYNSSFKNIFNNLFNEYMFLKKYINSNHNVYHKLIFFFSCKHYLKKLNYLLSIFYDVIEENDEDLMLEFYKEIKNNRRLLYYIGRILSNYLTCIAYKKVVYIIIICFARVHTVLNCILISEPFKSIIPELLNIINHIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H146</accession>
    <name>A0A1J1H146_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Vesicle transport v-SNARE protein VTI1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00457700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529800.1">
        <property type="nucleotide sequence ID" value="XM_028673338.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H146"/>
    <dbReference type="GeneID" id="39733110"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00457700"/>
    <dbReference type="OMA" id="NAHNELN"/>
    <dbReference type="OrthoDB" id="385338at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230:SF1">
        <property type="entry name" value="GOLGI SNAP RECEPTOR COMPLEX MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230">
        <property type="entry name" value="VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="296"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="31"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="313"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="324"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG96997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="334" mass="39829" checksum="ED68C985CF3386AB" modified="2017-02-15" version="1">MSDALYNDYKNNYDEYMKTVLYTEKIINDNNSDQNKLLNIYEKAIKSAENMFKRMQLEVETNSMIENAHNELNDMYNEISKCKTKLRKLKEEIMKKDQRNNELNNYDDRILLLSDVDLLEKGDVYINQSKILMDNTEYISNDVMKNLNKQRECIKKNISNISFVSDKLDQAKKIMKNLKNKEILNKYRLYIIFFFIFLTFFLIVCVKYNRYTKNNSNSYIQEKNNALIDFMNNEEINNLDNNNSNNLVNKLNDVYESNSIMYDFTEKNKNSEKPINNKNFHESSVKINKGENYFYDNSNKNVDEYNVNENEDENKNKDKDENNSINEDGSFNEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H158</accession>
    <name>A0A1J1H158_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aspartyl protease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00484600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530069.1">
        <property type="nucleotide sequence ID" value="XM_028673636.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H158"/>
    <dbReference type="GeneID" id="39733379"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00484600"/>
    <dbReference type="OMA" id="NKGMYLL"/>
    <dbReference type="OrthoDB" id="377242at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009618965" description="Aspartyl protease" evidence="2">
        <location>
            <begin position="18"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="629"/>
            <end position="649"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="818" mass="96736" checksum="BE556CE52EDEA4B1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2J9</accession>
    <name>A0A1J1H2J9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00513900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530367.1">
        <property type="nucleotide sequence ID" value="XM_028673967.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2J9"/>
    <dbReference type="GeneID" id="39733672"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00513900"/>
    <dbReference type="OMA" id="NFFEEYE"/>
    <dbReference type="OrthoDB" id="372569at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="554" mass="66309" checksum="9878E5F4739EB91A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2012-05-16" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>H7CDW8</accession>
    <name>H7CDW8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Apicoplast ribosomal protein L4, putative</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Large subunit ribosomal protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpl4</name>
        <name evidence="5" type="synonym">RPL4</name>
        <name evidence="5" type="ORF">PGAL8A_API01200</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <geneLocation type="apicoplast" evidence="4"/>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Mol. Biol. Evol." volume="29" first="2095" last="2099">
            <title>The Plasmodium Apicoplast Genome: Conserved Structure and Close Relationship of P. ovale to Rodent Malaria Parasites.</title>
            <authorList>
                <person name="Arisue N."/>
                <person name="Hashimoto T."/>
                <person name="Mitsui H."/>
                <person name="Palacpac N.M.Q."/>
                <person name="Kaneko A."/>
                <person name="Kawai S."/>
                <person name="Hasegawa M."/>
                <person name="Tanabe K."/>
                <person name="Horii T."/>
            </authorList>
            <dbReference type="PubMed" id="22396524"/>
            <dbReference type="DOI" id="10.1093/molbev/mss082"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">A8</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <dbReference type="EMBL" id="AB649424">
        <property type="protein sequence ID" value="BAL70738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LN835293">
        <property type="protein sequence ID" value="CRG98227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009325454.1">
        <property type="nucleotide sequence ID" value="NC_031963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="H7CDW8"/>
    <dbReference type="GeneID" id="30315769"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_API01200"/>
    <dbReference type="OrthoDB" id="275876at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Apicoplast API"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_uL4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_uL4_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="Ribosomal protein L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0933">Apicoplast</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAL70738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG98227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="199" mass="24359" checksum="B8A0EF59146B0BC6" modified="2012-05-16" version="1">MNIIMLNINNNIFNIIFKYKYNFFIKLYLNNYIKTCKLLVYILKYYFLYDKNRYKHTKNKSLINFSNKKIRIQKGLGKSRLRNFKSPICKQGSCNFGPFYTKKIIKYNNLKYKLVFLYLLLNKRSNIIIIKLEDLIKFLNYMYNYYSNNVFNLNFLINKIIYFNGILNRYLIIYLNQILNFNSNIILNLIKYNYIIIML</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKV2</accession>
    <name>A0A1J1GKV2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ubiquitin-conjugating enzyme E2 N, putative</fullName>
            <ecNumber evidence="6">6.3.2.19</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">UBC13</name>
        <name evidence="6" type="ORF">PGAL8A_00074400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.19" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525862.1">
        <property type="nucleotide sequence ID" value="XM_028675067.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKV2"/>
    <dbReference type="GeneID" id="39729269"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00074400"/>
    <dbReference type="OMA" id="ANFKHFF"/>
    <dbReference type="OrthoDB" id="7851174at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd23813">
        <property type="entry name" value="UBCc_UBE2N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000073">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="5">
        <location>
            <begin position="2"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="3">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="152" mass="17357" checksum="F8E479E7A8C064D2" modified="2017-02-15" version="1">MSIPRRITKETQNLANEPPPGIIAVPVPENYRHFKILINGPEGTPYEGGTYKLELFLPEQYPMEPPKVRFLTKIYHPNIDKLGRICLDILKDKWSPALQIRTVLLSIQALLSSPEPDDPLDSKVAEHFKQDKNDAENVAKQWNKIYANNTVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKV7</accession>
    <name>A0A1J1GKV7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00071300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525831.1">
        <property type="nucleotide sequence ID" value="XM_028674723.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKV7"/>
    <dbReference type="GeneID" id="39729238"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00071300"/>
    <dbReference type="OrthoDB" id="378169at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="401"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="937" mass="111149" checksum="AE613FF50644D474" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKY5</accession>
    <name>A0A1J1GKY5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00068400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG92980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525802.1">
        <property type="nucleotide sequence ID" value="XM_028671754.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729209"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00068400"/>
    <dbReference type="OrthoDB" id="413572at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052623">
        <property type="entry name" value="DAAF5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16216">
        <property type="entry name" value="DYNEIN ASSEMBLY FACTOR 5, AXONEMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16216:SF2">
        <property type="entry name" value="DYNEIN AXONEMAL ASSEMBLY FACTOR 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="248"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="276"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="310"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="399"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="787"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="973"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1092"/>
            <end position="1116"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="509"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG92980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1481" mass="179900" checksum="41DF8057E42B00E8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL05</accession>
    <name>A0A1J1GL05_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00378300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000011">
        <property type="protein sequence ID" value="CRG93070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525892.1">
        <property type="nucleotide sequence ID" value="XM_028670155.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL05"/>
    <dbReference type="GeneID" id="39732313"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00378300"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="138" mass="16697" checksum="7E059BFEA4BB7DF9" modified="2017-02-15" version="1">MKTFTLYLKIFTFLLLIWIFHCLYNYDSSKSLINRDTLQAKIGLKHERMLAEGDISDKKSAYFKKRVEHYPSGEKEFLLHELVHLMYMYIECYNANIKTNIVDNVLLNEENEIRYICRNKILNAYRNNISEERRLEEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLE9</accession>
    <name>A0A1J1GLE9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00086800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525986.1">
        <property type="nucleotide sequence ID" value="XM_028671200.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLE9"/>
    <dbReference type="GeneID" id="39729392"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00086800"/>
    <dbReference type="OrthoDB" id="363546at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="150" mass="17900" checksum="B7B68ACA4B65126A" modified="2017-02-15" version="1">MNEEMIDEMIENSLKSSDTENPYFLQQNNIYWETGHRTYIPFFHFLIHKYTNKIVDDQIRKFTNRVKSIHHTPFVFHKDGYFRSYYGDPDINMIFNLKKNTNFVFNSTGSLNSYNLLSNNCTYNKSTYIFDQILMSAFKLDLKDVLENSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLJ1</accession>
    <name>A0A1J1GLJ1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin carboxyl-terminal hydrolase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00098400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526100.1">
        <property type="nucleotide sequence ID" value="XM_028672466.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729508"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00098400"/>
    <dbReference type="OrthoDB" id="289038at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031647">
        <property type="term" value="P:regulation of protein stability"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00121">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000137">
        <property type="entry name" value="Putative ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002083">
        <property type="entry name" value="MATH/TRAF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF644">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="USP" evidence="2">
        <location>
            <begin position="637"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="482"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="560"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1193"/>
            <end position="1222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1314"/>
            <end position="1354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1639"/>
            <end position="1660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2215"/>
            <end position="2234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="567"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="589"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1209"/>
            <end position="1222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1330"/>
            <end position="1354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1650"/>
            <end position="1660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2215"/>
            <end position="2227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2839" mass="333218" checksum="BDB5D69C0A800152" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM68</accession>
    <name>A0A1J1GM68_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Prohibitin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00122500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the prohibitin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526340.1">
        <property type="nucleotide sequence ID" value="XM_028674739.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM68"/>
    <dbReference type="GeneID" id="39729750"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00122500"/>
    <dbReference type="OMA" id="YMSSDDI"/>
    <dbReference type="OrthoDB" id="275637at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03401">
        <property type="entry name" value="SPFH_prohibitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.479.30:FF:000001">
        <property type="entry name" value="Prohibitin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000163">
        <property type="entry name" value="Prohibitin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222">
        <property type="entry name" value="PROHIBITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222:SF0">
        <property type="entry name" value="PROHIBITIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00679">
        <property type="entry name" value="PROHIBITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="3">
        <location>
            <begin position="25"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU366048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="272" mass="30506" checksum="4E9939B4934F3126" modified="2017-02-15" version="1">MEKVLSSIGKLSVVAGGLSLIPYTFIYDVDGGERCVMFNRFGGVSEKTYGEGSHFYIPWFQTPYIYDIKMKPKVINTTTGTRDLQIVTISLRLLFRPHTQHLPYLHSTLGPDYDERVLPSIGNEVLKAVVAKYNAESLLTQRDKISKEIRESITARAKHFNIMLDDVAITHLSYGKEFAKAIEDKQVAQQESERVKFIVAKTEQEKIAAVIKAQGEAEAAKLISTAVKEYGNSLLEIRKLEAAKEIAENLSKSKNITYFPSSSNILLNTKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMF2</accession>
    <name>A0A1J1GMF2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">C-13 antigen</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00113500</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the YIF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526251.1">
        <property type="nucleotide sequence ID" value="XM_028674143.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMF2"/>
    <dbReference type="GeneID" id="39729660"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00113500"/>
    <dbReference type="OMA" id="GIVHNIF"/>
    <dbReference type="OrthoDB" id="337750at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005793">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005578">
        <property type="entry name" value="Yif1_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14083">
        <property type="entry name" value="YIP1 INTERACTING FACTOR HOMOLOG YIF1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14083:SF0">
        <property type="entry name" value="YIP1D-INTERACTING FACTOR 1, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03878">
        <property type="entry name" value="YIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="318"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="437"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="469"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="513"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="593"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="631"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG93429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="652" mass="77956" checksum="F497FE0A303BDCAA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMJ1</accession>
    <name>A0A1J1GMJ1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sorting assembly machinery 50 kDa subunit, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SAM50</name>
        <name evidence="4" type="ORF">PGAL8A_00136900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526486.1">
        <property type="nucleotide sequence ID" value="XM_028674902.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMJ1"/>
    <dbReference type="GeneID" id="39729894"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00136900"/>
    <dbReference type="OMA" id="MIGTNVN"/>
    <dbReference type="OrthoDB" id="1724197at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.50">
        <property type="entry name" value="membrane protein fhac: a member of the omp85/tpsb transporter family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000184">
        <property type="entry name" value="Bac_surfAg_D15"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01103">
        <property type="entry name" value="Omp85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bacterial surface antigen (D15)" evidence="3">
        <location>
            <begin position="100"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="450" mass="53033" checksum="C9401B695D16D7E9" modified="2017-02-15" version="1">MNIELDLKKKIDNIIINLDGINKIKKSNLNFIFDEIKKSNNVEELFFNIKKCNYKIDNLNIFDGDPIVKLSSSNKNVIIDYKLKERKNNYMIGTNVNNRGEVTADFEINMPYIFKTINSAELKANICSLSTNNFSFRLLIPHLKYLANYRLILESNISSINNIKCSSYITKMNSIKTYLLKNNHSLIWEVNYNKILHNINKNFIPSEKILKLCDQYIKNTIKYNYKKDKLNYSLSSEKNEEVIYSHYPTSGYYYEIENEVSLPFCEAKFFKNHINFLYIKKLIENLYAYFNISNGIKYDYGKKNISYLNNFNFTGSIGSSLILRGFEYNSVGSTEECFKFDKKEKNYKINYNYLGANFFSNIQFIFKYILNFNNINPILFFYLQLGRLSNNLFPSFKQLINDTRISTGIGIMSYIQKNISLELFFCFPLWYQLTDKIKFFQVGLNFKGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMM5</accession>
    <name>A0A1J1GMM5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcription factor Pcc1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00139200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CTAG/PCC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526508.1">
        <property type="nucleotide sequence ID" value="XM_028674926.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMM5"/>
    <dbReference type="GeneID" id="39729916"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00139200"/>
    <dbReference type="OMA" id="HTIEVNC"/>
    <dbReference type="OrthoDB" id="373700at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.50">
        <property type="entry name" value="Alpha-D-phosphohexomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015419">
        <property type="entry name" value="CTAG/Pcc1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09341">
        <property type="entry name" value="Pcc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="84" mass="10065" checksum="5472614A93922912" modified="2017-02-15" version="1">MGEYNIVTHIIEIYCSTEKYSNILYKCLSSDESLKQNQMFKHANIYGNKIKIELQSNTYEDLRYKAKNIYDYLHFFFKTVEAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMM6</accession>
    <name>A0A1J1GMM6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00129400</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526409.1">
        <property type="nucleotide sequence ID" value="XM_028674816.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMM6"/>
    <dbReference type="GeneID" id="39729819"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00129400"/>
    <dbReference type="OMA" id="RNIQKCY"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd08217">
        <property type="entry name" value="STKc_Nek2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000151">
        <property type="entry name" value="G2-specific protein kinase nimA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051131">
        <property type="entry name" value="NEK_Ser/Thr_kinase_NIMA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44899">
        <property type="entry name" value="CAMK FAMILY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44899:SF3">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE NEK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="15"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="389"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG93587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="852" mass="101600" checksum="E391BE50258E74F8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMT5</accession>
    <name>A0A1J1GMT5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00142700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526543.1">
        <property type="nucleotide sequence ID" value="XM_028674964.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMT5"/>
    <dbReference type="GeneID" id="39729951"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00142700"/>
    <dbReference type="OMA" id="KYIEQVM"/>
    <dbReference type="OrthoDB" id="5334309at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017868">
        <property type="entry name" value="Filamin/ABP280_repeat-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00630">
        <property type="entry name" value="Filamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50194">
        <property type="entry name" value="FILAMIN_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="Filamin" evidence="1">
        <location>
            <begin position="308"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="739"/>
            <end position="777"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="853" mass="100906" checksum="D175FD5BA0BB1317" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMV4</accession>
    <name>A0A1J1GMV4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00145100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526567.1">
        <property type="nucleotide sequence ID" value="XM_028674991.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMV4"/>
    <dbReference type="GeneID" id="39729975"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00145100"/>
    <dbReference type="OMA" id="CDNNKYC"/>
    <dbReference type="OrthoDB" id="372740at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="897"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1017"/>
            <end position="1037"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1238" mass="151942" checksum="5E9719D0270A989A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNJ2</accession>
    <name>A0A1J1GNJ2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Phosphatidylserine synthase I, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PGAL8A_00173300</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12">Phospholipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526847.1">
        <property type="nucleotide sequence ID" value="XM_028670057.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNJ2"/>
    <dbReference type="GeneID" id="39730260"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00173300"/>
    <dbReference type="OMA" id="YMENCNS"/>
    <dbReference type="OrthoDB" id="10265393at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106245">
        <property type="term" value="F:L-serine-phosphatidylethanolamine phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006659">
        <property type="term" value="P:phosphatidylserine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004277">
        <property type="entry name" value="PSS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15362">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15362:SF7">
        <property type="entry name" value="PHOSPHATIDYLSERINE SYNTHASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03034">
        <property type="entry name" value="PSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="247"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="280"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="310"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="349"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG94026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="372" mass="43895" checksum="E24DA54C4EEE4A6F" modified="2017-02-15" version="1">MSIYNFFLYIYIFYRRRSLYLLCFSLIVSLILSNSIILLEFKHRIIISLIISFFNLCVLKNVIQKIIFTIKKDVFTILINSVIIFYYVIIVFCQFFSPNEIKYIIKIFNKNIVFYTAEKSYMENCNSLNNITDKLDIFVIAHLLGWFIKGFAMRNFFLLNLNSVLFELLELRFQHLLPNFYECWWDHVILDVLGCNLIGIMLSIFVMKYFNIPFFDWTIPDKIKPKKKNLIFPTLDKLCRKVFKNSASLLLLIFYSIIVNIIDLNIFFLKAELNLYPTNYIIFLRTGLVVIICVKASIELHNCISREASIDGVFYVFIVVTIFLLELLLCVKWKHNLKSDNSDLTVINATWLLITSTFSSILLFLYANECLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNT6</accession>
    <name>A0A1J1GNT6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nucleolar protein 5, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">NOP5</name>
        <name evidence="7" type="ORF">PGAL8A_00384900</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NOP5/NOP56 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526966.1">
        <property type="nucleotide sequence ID" value="XM_028670189.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNT6"/>
    <dbReference type="GeneID" id="39732379"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00384900"/>
    <dbReference type="OMA" id="NRMMVLA"/>
    <dbReference type="OrthoDB" id="6780543at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031428">
        <property type="term" value="C:box C/D methylation guide snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.246.90:FF:000005">
        <property type="entry name" value="Nucleolar protein 5, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.4070:FF:000001">
        <property type="entry name" value="Probable Nucleolar protein 58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.4070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.90">
        <property type="entry name" value="Nop domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045056">
        <property type="entry name" value="Nop56/Nop58"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012974">
        <property type="entry name" value="NOP58/56_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042239">
        <property type="entry name" value="Nop_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002687">
        <property type="entry name" value="Nop_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036070">
        <property type="entry name" value="Nop_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012976">
        <property type="entry name" value="NOSIC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10894">
        <property type="entry name" value="NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10894:SF1">
        <property type="entry name" value="NUCLEOLAR PROTEIN 58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01798">
        <property type="entry name" value="Nop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08156">
        <property type="entry name" value="NOP5NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00931">
        <property type="entry name" value="NOSIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89124">
        <property type="entry name" value="Nop domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51358">
        <property type="entry name" value="NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Nop" evidence="6">
        <location>
            <begin position="285"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="407"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="412"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="424"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="442"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="457"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG94145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="466" mass="52900" checksum="837D6B7D0149F362" modified="2017-02-15" version="1">MLILVETAAGYGLFKVENSKLIESDIKDIEKCFENAEEARKNVSLYSFSKFKKFQNAFDETNSLMESKLGKGLKKFLKKNIVKPKLNESLALCDKALGGIIKKKFNINVTYTNSTQEIIRGIKTHIYDLLVGVKEEDSKLLKLSLSHSLNRFKLKFSADKVDVMIVQAVGLLEDLDKEINVFSMRLKEWYGWHFPELGKIITDNKIYAKCVKIIGFRSNAKNVNLLEETTEEIQKEIKQLAEISMGTEIEEDDLNCINELADRLLELTDYRESLATYLKYRMNSIAPNLTYLVGDLIGAKLIARAGSLISLAKHPSSTLQILGSEKALFRALKTKSKTPKYGLIYHATIVGQTSPKLKGKISRSLAAKLSLCTRVDALGNFSEPSIAIACKSDLEKRLEYITNNLQKKVNPSGSKSQSQQIQQNKYNPNQSNDVQNKNLFNKKNDFRFKREADKNNKKFIKKQKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNW0</accession>
    <name>A0A1J1GNW0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Exonuclease, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00168900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526803.1">
        <property type="nucleotide sequence ID" value="XM_028670008.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNW0"/>
    <dbReference type="GeneID" id="39730216"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00168900"/>
    <dbReference type="OMA" id="SFFKWLL"/>
    <dbReference type="OrthoDB" id="10261556at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052408">
        <property type="entry name" value="Exonuclease_MUT-7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47765">
        <property type="entry name" value="3'-5' EXONUCLEASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47765:SF2">
        <property type="entry name" value="EXONUCLEASE MUT-7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3'-5' exonuclease" evidence="1">
        <location>
            <begin position="604"/>
            <end position="678"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="709" mass="85098" checksum="31D5B9FF1A163F34" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNW6</accession>
    <name>A0A1J1GNW6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UV excision repair protein RAD23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00387900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the RAD23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526996.1">
        <property type="nucleotide sequence ID" value="XM_028670223.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNW6"/>
    <dbReference type="GeneID" id="39732409"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00387900"/>
    <dbReference type="OMA" id="PHMLEPI"/>
    <dbReference type="OrthoDB" id="419317at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd14280">
        <property type="entry name" value="UBA1_Rad23_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14281">
        <property type="entry name" value="UBA2_Rad23_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01805">
        <property type="entry name" value="Ubl_Rad23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000002">
        <property type="entry name" value="UV excision repair protein RAD23 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000003">
        <property type="entry name" value="UV excision repair protein RAD23 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.540">
        <property type="entry name" value="XPC-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004806">
        <property type="entry name" value="Rad23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015360">
        <property type="entry name" value="XPC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036353">
        <property type="entry name" value="XPC-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10621">
        <property type="entry name" value="UV EXCISION REPAIR PROTEIN RAD23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10621:SF0">
        <property type="entry name" value="UV EXCISION REPAIR PROTEIN RAD23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09280">
        <property type="entry name" value="XPC-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01839">
        <property type="entry name" value="RAD23PROTEIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101238">
        <property type="entry name" value="XPC-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3 5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="8">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="7">
        <location>
            <begin position="152"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="7">
        <location>
            <begin position="331"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="79"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="86"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="96"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="381" mass="43674" checksum="1174AB95C4B97F10" modified="2017-02-15" version="1">MIIKVRTLQNNEEEINVDKDDTIFDLKKKVENVLPDMPSDKQKLIFSGKILKDESKAVDILNENDIIIVMVTRKIFNKNNSKDDVNNTSSNSLKNNDNKLNDSKVNTDNKALNINDNINALNKNEQKIEENENNNIESKQIENVDNAESMLLIGEKLKETIDNICAMGFEKENVEKAMILAYNNPNRAIDYLTNGFPASNDTNENAYEREDVGNIPNLSNLLINDNLLGENQRQSSSQNPELFRNSPFFNVLRDVALSNPQRIPEILEMIGRTDPSFLEYIREHQGEFLRAIQNYNNENVENEQPNEASIEQNNQNIIDQSNESYNIPITPLNENEMESIKKLESLGFPKHIALEAFIACDKNEEMAANYLFENMNDYFSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP32</accession>
    <name>A0A1J1GP32_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DNA replication licensing factor MCM3</fullName>
            <ecNumber evidence="11">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">MCM3</name>
        <name evidence="14" type="ORF">PGAL8A_00074300</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the MCM2-7 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="11"/>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525861.1">
        <property type="nucleotide sequence ID" value="XM_028675056.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP32"/>
    <dbReference type="GeneID" id="39729268"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00074300"/>
    <dbReference type="OMA" id="EANHIMV"/>
    <dbReference type="OrthoDB" id="1882346at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902975">
        <property type="term" value="P:mitotic DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008046">
        <property type="entry name" value="Mcm3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF46">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01659">
        <property type="entry name" value="MCMPROTEIN3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 11" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="13">
        <location>
            <begin position="392"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="791"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="791"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="823"/>
            <end position="839"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG93039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="956" mass="109116" checksum="FEC6CFC6077B3415" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP43</accession>
    <name>A0A1J1GP43_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Elongation factor 1 (EF-1), putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00396700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EF-1-beta/EF-1-delta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527084.1">
        <property type="nucleotide sequence ID" value="XM_028670320.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP43"/>
    <dbReference type="GeneID" id="39732497"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00396700"/>
    <dbReference type="OMA" id="IKPYGEE"/>
    <dbReference type="OrthoDB" id="331763at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005853">
        <property type="term" value="C:eukaryotic translation elongation factor 1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00292">
        <property type="entry name" value="EF1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.60:FF:000001">
        <property type="entry name" value="Elongation factor 1-beta 1 like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036219">
        <property type="entry name" value="eEF-1beta-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049720">
        <property type="entry name" value="EF1B_bsu/dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014038">
        <property type="entry name" value="EF1B_bsu/dsu_GNE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribsomal_bS6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11595">
        <property type="entry name" value="EF-HAND AND COILED-COIL DOMAIN-CONTAINING FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11595:SF21">
        <property type="entry name" value="ELONGATION FACTOR 1-BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00736">
        <property type="entry name" value="EF1_GNE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00888">
        <property type="entry name" value="EF1_GNE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54984">
        <property type="entry name" value="eEF-1beta-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Translation elongation factor EF1B beta/delta subunit guanine nucleotide exchange" evidence="5">
        <location>
            <begin position="45"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="137"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG94263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="165" mass="19143" checksum="6543E76C9A8B4DCC" modified="2017-02-15" version="1">MANIYDELYIPLSYYILHNDGKNLNTNNEKINTNKKTNKKEVINKSSLIIEIKPYGENTDLDYVLKLVKEIKIDGLTWGEAYKKIPFAFGLFKLQVSCVIVDDLVNTDEIIEMIENIGLDEEQCKKKKELEAKQTENDEFEEEEEEEEEIEGLVQSAEIISFNKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP52</accession>
    <name>A0A1J1GP52_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00179000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000021">
        <property type="protein sequence ID" value="CRG94078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526899.1">
        <property type="nucleotide sequence ID" value="XM_028670115.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730317"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00179000"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="337"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="777"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1418"/>
            <end position="1470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="28"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="378"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="398"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="424"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="459"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="777"/>
            <end position="796"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1612" mass="190015" checksum="C2831B5070A2E057" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP75</accession>
    <name>A0A1J1GP75_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00399900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Haemosporida</taxon>
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            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
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    </organism>
    <reference evidence="3" key="1">
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                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527116.1">
        <property type="nucleotide sequence ID" value="XM_028670356.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP75"/>
    <dbReference type="GeneID" id="39732529"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00399900"/>
    <dbReference type="OMA" id="EIYLCNI"/>
    <dbReference type="OrthoDB" id="385175at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
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    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="2">
        <location>
            <begin position="769"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="596"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="600"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="895" mass="107627" checksum="0D2DEF41A82272BC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPQ5</accession>
    <name>A0A1J1GPQ5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00179400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
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            <taxon>Apicomplexa</taxon>
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            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="GeneID" id="39730321"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00179400"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
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    </dbReference>
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    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
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            <end position="690"/>
        </location>
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            <end position="543"/>
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        <location>
            <begin position="1884"/>
            <end position="1931"/>
        </location>
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            <begin position="1459"/>
            <end position="1486"/>
        </location>
    </feature>
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            <begin position="378"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="444"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
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            <begin position="511"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="524"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1884"/>
            <end position="1898"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1899"/>
            <end position="1923"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1931" mass="229140" checksum="0C54DDB4012EDA10" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPR1</accession>
    <name>A0A1J1GPR1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00098500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Haemosporida</taxon>
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            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_028672477.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729509"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00098500"/>
    <dbReference type="OMA" id="HNNCLHN"/>
    <dbReference type="OrthoDB" id="392641at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1413"/>
            <end position="1443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1614"/>
            <end position="1638"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="3306"/>
            <end position="3323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="3386"/>
            <end position="3408"/>
        </location>
    </feature>
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        <location>
            <begin position="2718"/>
            <end position="2739"/>
        </location>
    </feature>
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        <location>
            <begin position="733"/>
            <end position="800"/>
        </location>
    </feature>
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            <begin position="2178"/>
            <end position="2188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2718"/>
            <end position="2729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2730"/>
            <end position="2739"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="4180" mass="507657" checksum="62B32FEA994A27F3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPU5</accession>
    <name>A0A1J1GPU5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00402800</name>
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    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
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            <taxon>Sar</taxon>
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            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527145.1">
        <property type="nucleotide sequence ID" value="XM_028670387.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732558"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00402800"/>
    <dbReference type="OMA" id="YTNFLMN"/>
    <dbReference type="OrthoDB" id="372927at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1108"/>
            <end position="1128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1341"/>
            <end position="1369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1450"/>
            <end position="1567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1611"/>
            <end position="1635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1757"/>
            <end position="1805"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="965"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1119"/>
            <end position="1128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1347"/>
            <end position="1369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1450"/>
            <end position="1463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1531"/>
            <end position="1563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1626"/>
            <end position="1635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1762"/>
            <end position="1789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1790"/>
            <end position="1805"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1874" mass="220449" checksum="3C1380E175E94382" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ28</accession>
    <name>A0A1J1GQ28_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00083400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525952.1">
        <property type="nucleotide sequence ID" value="XM_028670821.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ28"/>
    <dbReference type="GeneID" id="39729358"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00083400"/>
    <dbReference type="OrthoDB" id="332269at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="120" mass="14377" checksum="8A07FDCA07D6D288" modified="2017-02-15" version="1">MENTQYYNRLFDLNLLAENVFCQNKKLLLIDNNLNGIRETKRGYRRNEIFKNKGHLSVYNNIFLLLSKSQINDHLENVEKILLERRDKIRDKRKSLIKELIELNPSVTEMPLEEAKFLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ37</accession>
    <name>A0A1J1GQ37_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glideosome associated protein with multiple membrane spans 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">GAPM2</name>
        <name evidence="2" type="ORF">PGAL8A_00193700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000029">
        <property type="protein sequence ID" value="CRG94539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527354.1">
        <property type="nucleotide sequence ID" value="XM_028670619.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ37"/>
    <dbReference type="GeneID" id="39730462"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00193700"/>
    <dbReference type="OMA" id="MFIFYWA"/>
    <dbReference type="OrthoDB" id="359547at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021691">
        <property type="entry name" value="DUF3273"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11677">
        <property type="entry name" value="DUF3273"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="372" mass="42584" checksum="53AECE041870B7F9" modified="2017-02-15" version="1">MYTYGVEGDDGYLQQAQYPSPYENQYQQDEESPSPRGESHTPFIGYFSSHLLRTGFFLQCVSLILMFIFYWAFGGTGIFVFDLYAGPECVKVSSAFHLTISILMAIYLLGTLYIAMFQVFVADNSKWCRGFRAGSKLLSAAVTLDLLSSILRLVQYLYAYFYMNMRWWARYQQTKSDWTLLHFGSIVHSFALFIYGAAFFYMEAYHDEGTYEELAWSNLTLFKLAGLAELLMVFSGFGAFFSILLLGAIICATIWAFSFEPLLEKWSPELHSRDINADVLPEIKNDEEQCGYNEENAYAPYNANPENMGYGEEMIQQNMNDNYVEGNAYDQNIYGQNDGIPTTYDYSQIEGQIQQNAEMGVSENNYAKNGQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ39</accession>
    <name>A0A1J1GQ39_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00180100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527233.1">
        <property type="nucleotide sequence ID" value="XM_028670485.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ39"/>
    <dbReference type="GeneID" id="39730328"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00180100"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="79" mass="9054" checksum="983D111896F00879" modified="2017-02-15" version="1">MDPEHNKNNSFNKSTCNISKIYDMLSPYLIPLLVGISCTILGLWIYIAYKKIQRANNNMDNLSLDSGFAEYEVYDAEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQC6</accession>
    <name>A0A1J1GQC6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00203900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527458.1">
        <property type="nucleotide sequence ID" value="XM_028670735.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQC6"/>
    <dbReference type="GeneID" id="39730566"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00203900"/>
    <dbReference type="OMA" id="LTCWELN"/>
    <dbReference type="OrthoDB" id="370739at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="187" mass="22209" checksum="65897A6E9BA4ADEB" modified="2017-02-15" version="1">MNDILCEDNKIKYKNVVSIYTIRMYINGFIIGYVFRQEIHRKFYIYKKDNIIFSLIKKNIYIKNNTKKLQNSFNLAKHSLYNTRLNNKLNFNNKNINFFFKLPLFNILLNFKNNIQISNFLAFRLSFWTCVCTFCCCKLNKSMDNSIIPPIISGIFASSVSKLIFRENKKILIPTWLGCVLSYVIYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQF2</accession>
    <name>A0A1J1GQF2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">U3 snoRNA-associated small subunit rRNA processing, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00207200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527490.1">
        <property type="nucleotide sequence ID" value="XM_028670771.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730599"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00207200"/>
    <dbReference type="OMA" id="MNIPLTC"/>
    <dbReference type="OrthoDB" id="338608at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034388">
        <property type="term" value="C:Pwp2p-containing subcomplex of 90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051570">
        <property type="entry name" value="TBC1_cilium_biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19853">
        <property type="entry name" value="WD REPEAT CONTAINING PROTEIN 3 WDR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19853:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25173">
        <property type="entry name" value="Beta-prop_WDR3_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25172">
        <property type="entry name" value="Beta-prop_WDR3_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="105"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="853"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="297"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="514"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1259"/>
            <end position="1320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="514"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="544"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="592"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1267"/>
            <end position="1284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1293"/>
            <end position="1305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1320" mass="155250" checksum="C43C6B8AC19D0D65" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQH4</accession>
    <name>A0A1J1GQH4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Phospholipid/glycerol acyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00206900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527487.1">
        <property type="nucleotide sequence ID" value="XM_028670768.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQH4"/>
    <dbReference type="GeneID" id="39730596"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00206900"/>
    <dbReference type="OMA" id="LWKNEIF"/>
    <dbReference type="OrthoDB" id="272512at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23063:SF61">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_7, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23063">
        <property type="entry name" value="PHOSPHOLIPID ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="341" mass="40438" checksum="2F2D04CB6216A712" modified="2017-02-15" version="1">MEKYREFSDSSTGINPFLPVWVNKKLNFHEKLLKILLLPLVICRLCFICLTLIFMFFLNSMLKLLIFQCVKDFFNQIIQTIYCRLLLFYLGFFYLDEQYASNKRLKIKCNKQKIPFTYDDYGHIFLSNFTSFVDILYLAFRLNPLFIVINKNGSLSPVCFFDILKLSLQFSIPNELGLFKNIEEVHNYAKNEKIRNVVIFPEAMKSNGSCILLWKNEIFMNSDHILKNKCNLIAFIYEINLINKKLNQFYTSPHTVFHPLIHIALLCFNIYNKIKIVWLNEKDISESLKEKEFENNEEFVSNLRNLMGQMKSIGGILVNVKGDMLEKFVNYWNLTRKKEYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQU1</accession>
    <name>A0A1J1GQU1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Telomere length and silencing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00227600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TLS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527694.1">
        <property type="nucleotide sequence ID" value="XM_028670997.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQU1"/>
    <dbReference type="GeneID" id="39730803"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00227600"/>
    <dbReference type="OMA" id="KGINADN"/>
    <dbReference type="OrthoDB" id="5627at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010756">
        <property type="entry name" value="Tls1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13486:SF2">
        <property type="entry name" value="SPLICING FACTOR C9ORF78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13486">
        <property type="entry name" value="TELOMERE LENGTH AND SILENCING PROTEIN 1 TLS1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07052">
        <property type="entry name" value="Hep_59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="198" mass="23617" checksum="5524D10A9F558CFE" modified="2017-02-15" version="1">MIKKRKLKTDNKCMRIPLEKDEDLKIQESTKNELIHKNFKILKLETSKNLKLLQNIRLKKKGINADNIIYESKVLEKNEKEKKLLDKQFTKNITEKEIEDAHVESFIRENMKEFYEEKDEKKKKKEEQDDIVKDLYKISDHLKVKSSINDNSEKLNCITGITEIPLPLEIKLKNIEETEKIKRKFLRNAKFLNTESNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQW3</accession>
    <name>A0A1J1GQW3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00204800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527467.1">
        <property type="nucleotide sequence ID" value="XM_028670745.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQW3"/>
    <dbReference type="GeneID" id="39730575"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00204800"/>
    <dbReference type="OMA" id="MTDVQIQ"/>
    <dbReference type="OrthoDB" id="639027at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21546">
        <property type="entry name" value="SPOC_FPA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052462">
        <property type="entry name" value="SLIRP/GR-RBP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012921">
        <property type="entry name" value="SPOC_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48027">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07744">
        <property type="entry name" value="SPOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="30"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="126"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="563"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="126"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="571"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="653" mass="75649" checksum="3749860207A44573" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQY6</accession>
    <name>A0A1J1GQY6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00207300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527491.1">
        <property type="nucleotide sequence ID" value="XM_028670772.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQY6"/>
    <dbReference type="GeneID" id="39730600"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00207300"/>
    <dbReference type="OrthoDB" id="371552at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="139" mass="16507" checksum="535A78BED0E0B092" modified="2017-02-15" version="1">MKSKKVNKLGGENFERGKTCRKNKILVNPHKNNREIKEKTVNEEIHHLSDYLKDEANEKSNENIYNELNKNIYDESNENVFEELNDNLSNFVFKKKIYEKNIAQIEKKIQTNKLNKLIETKEIILDMLTIIKNRKLNLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQY9</accession>
    <name>A0A1J1GQY9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Basal complex transmembrane protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00140100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526517.1">
        <property type="nucleotide sequence ID" value="XM_028674936.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQY9"/>
    <dbReference type="GeneID" id="39729925"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00140100"/>
    <dbReference type="OMA" id="NVVFLYF"/>
    <dbReference type="OrthoDB" id="366215at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="579"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="625"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="663"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="307"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="714" mass="84629" checksum="A33E7B28ED7112D1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRI6</accession>
    <name>A0A1J1GRI6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Inner membrane complex suture component, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ISC1</name>
        <name evidence="1" type="ORF">PGAL8A_00252600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527934.1">
        <property type="nucleotide sequence ID" value="XM_028671264.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRI6"/>
    <dbReference type="GeneID" id="39731054"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00252600"/>
    <dbReference type="OMA" id="DEYPHIN"/>
    <dbReference type="OrthoDB" id="381329at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="457" mass="52777" checksum="F70C958029D2B9DF" modified="2017-02-15" version="1">MNNSGYDKSNNSQNVLNVNENDEKLSKDSINTESIVHNVSENISTIINTANNEITYNDHSYDDANVLRVPEKKSGQVTHGQNVTSVKSCDNLYLNESPQTKILYFPNNNYKQFNSPTDRKLRSSNGNFYNFDANTAWNMNYPINSENYDYLNVQTPSNNIPDACNVPYNLVENSQLISPEHTTSPLYTRRANIHQNPPFTDSCHLNPYSDINPFYGRMSSYSPLHNNELNYLCKPTLSSYENTSPYINYNYFKHMPPHLYYLAEDKDNCSFLKKGIKRAMNVCNSNINESYTPKYEYIIQGPKLPYVNYPNQKKFDVFKKLTLAVGTYLDDAVNIMIDVLESSFRIIKKNNNTNLYDLYPFYNPDPIYSRQERPTLKTGSNLFDKINCALDGTTLEKHKNLPKNFGRIIVPKTEKTGHVVVDGINNILDNLLNEPLSYRNYDYFSDKFKPMNEIKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS19</accession>
    <name>A0A1J1GS19_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">60S ribosomal protein L7, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00006500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528110.1">
        <property type="nucleotide sequence ID" value="XM_028671460.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS19"/>
    <dbReference type="GeneID" id="39728587"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00006500"/>
    <dbReference type="OMA" id="IVEPWIA"/>
    <dbReference type="OrthoDB" id="28644at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01657">
        <property type="entry name" value="Ribosomal_L7_archeal_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1390.20:FF:000004">
        <property type="entry name" value="60S ribosomal protein L7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.20">
        <property type="entry name" value="Ribosomal protein L30, ferredoxin-like fold domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036919">
        <property type="entry name" value="Ribo_uL30_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039699">
        <property type="entry name" value="Ribosomal_uL30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005998">
        <property type="entry name" value="Ribosomal_uL30_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035808">
        <property type="entry name" value="Ribosomal_uL30_euk_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016082">
        <property type="entry name" value="Ribosomal_uL30_ferredoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012988">
        <property type="entry name" value="Ribosomal_uL30_N_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01310">
        <property type="entry name" value="uL30_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11524">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11524:SF16">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00327">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08079">
        <property type="entry name" value="Ribosomal_L30_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55129">
        <property type="entry name" value="Ribosomal protein L30p/L7e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL30 N-terminal eukaryotes" evidence="6">
        <location>
            <begin position="23"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL30-like ferredoxin-like fold" evidence="5">
        <location>
            <begin position="93"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="257" mass="30699" checksum="8F2289E7B2837749" modified="2017-02-15" version="1">MADRYEEKGENEIGKNMTSLRNKKNKKNLELKEKNQKKLKALKLINKKKRSELRERILKYEQEYADERKKIVELKREARKNNCFYKEAEKKVVFVIRLKGINKLSPKVRSVFRLLRLLQVHNGVFVKVNKASKQMLKIVEPYITYGYPTLSTVRKLIYKRGYIKLGKVRRYSRKKIQDNEDISKYLGKYNVHGVEDMVYQIYTCGPAFKKVNNFLWTFKLKPPKKGFKAKRHGFNEPRPGDWGNRENHINELINRMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSB9</accession>
    <name>A0A1J1GSB9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAD synthase</fullName>
            <ecNumber evidence="2">2.7.7.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">FAD pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">FMN adenylyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PGAL8A_00391200</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>FMN + ATP + H(+) = FAD + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:17237"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="EC" id="2.7.7.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.2" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527029.1">
        <property type="nucleotide sequence ID" value="XM_028670259.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSB9"/>
    <dbReference type="GeneID" id="39732442"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00391200"/>
    <dbReference type="OMA" id="INECAYM"/>
    <dbReference type="OrthoDB" id="270728at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003919">
        <property type="term" value="F:FMN adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006747">
        <property type="term" value="P:FAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002500">
        <property type="entry name" value="PAPS_reduct_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23293:SF9">
        <property type="entry name" value="FAD SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23293">
        <property type="entry name" value="FAD SYNTHETASE-RELATED FMN ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01507">
        <property type="entry name" value="PAPS_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0288">FMN</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 15" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoadenosine phosphosulphate reductase" evidence="14">
        <location>
            <begin position="115"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG94208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="329" mass="39564" checksum="EC8F54B3634CDFB5" modified="2017-02-15" version="1">MDIEDNEEWNDYSNSLKFYEKIEKLYYEHMKEANKIKDCNKEISNPNILKDDNEVKSNIRGGNNNIIKPSMYNYDVINYYKDEVNLKKKAIELSEDIMEAIDYIYDIFRLCKKNVFLSFNGGKDAVVTLHLFRCAYARYIKDIKGKRKKPNLIYFKDEINEFPEVYQFINECAYMHDFNIIIIKGTWKNGVTHFIENFHKMYENDFLNQVKIPNIDPVSFYPTIAFINGTRYNDSYSEKLHILNISSRNFPPYLYLNPIFYWTYGAIWTFILYFKFNYCILYNHGYSSIGSMNDTVKNEFLKCNDCYLPAYFLKNWDYERYNRVSTKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSU4</accession>
    <name>A0A1J1GSU4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AP complex subunit sigma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00408000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the adaptor complexes small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527197.1">
        <property type="nucleotide sequence ID" value="XM_028670446.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSU4"/>
    <dbReference type="GeneID" id="39732610"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00408000"/>
    <dbReference type="OMA" id="IVCIENE"/>
    <dbReference type="OrthoDB" id="371463at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030117">
        <property type="term" value="C:membrane coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016635">
        <property type="entry name" value="AP_complex_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000804">
        <property type="entry name" value="Clathrin_sm-chain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11753">
        <property type="entry name" value="ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015588">
        <property type="entry name" value="AP_complex_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00989">
        <property type="entry name" value="CLAT_ADAPTOR_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AP complex mu/sigma subunit" evidence="7">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR015588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="141" mass="17259" checksum="9462621BAE905C0E" modified="2017-02-15" version="1">MLNFILLQNRQGKTRFSKWYINCNETKQKKIERDINKILINRSRSYANIFIYENFKIVYRLYAGLYFVVCIENENELYILEFIHFMAQLLDNFFTNVCELDLLFNFHFLYYFFDNIILGGYIYEVNKNIILDKINKIKKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT97</accession>
    <name>A0A1J1GT97_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Splicing factor 3B subunit 4, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00291800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SF3B4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528522.1">
        <property type="nucleotide sequence ID" value="XM_028671917.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT97"/>
    <dbReference type="GeneID" id="39731451"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00291800"/>
    <dbReference type="OMA" id="KDEDDIC"/>
    <dbReference type="OrthoDB" id="10259687at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097525">
        <property type="term" value="C:spliceosomal snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048026">
        <property type="term" value="P:positive regulation of mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12334">
        <property type="entry name" value="RRM1_SF3B4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12335">
        <property type="entry name" value="RRM2_SF3B4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000895">
        <property type="entry name" value="Hsh49p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000505">
        <property type="entry name" value="Splicing factor 3B subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034158">
        <property type="entry name" value="SF3B4_RRM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034159">
        <property type="entry name" value="SF3B4_RRM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052084">
        <property type="entry name" value="SF3B4_spliceosome_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48030">
        <property type="entry name" value="SPLICING FACTOR 3B SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48030:SF3">
        <property type="entry name" value="SPLICING FACTOR 3B SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="20"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="107"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="432"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="432"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="467"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="491"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG95714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="511" mass="57257" checksum="A252125EFD1B4101" modified="2017-02-15" version="1">MFVPHKNQEINHIYERNNEATLYIANLDSQVDEEILCELFMQCGNVKNVHIPRDKINGYHSGYGFVEYEYEYECEYAAKILNMTKLFGKPLRCNKASQDKRSFDVGANLFIGNLDKEVDEKMLFDIFSSFGQVITVKIMRNEDDTSKGHGFISYDNFESSDLAIENMNNQFICNKKVHISYAFKKDTKGERHGTAAERFIAANKALNMYPVNENANNIFPYNSTSVVNPTNNNASLNNLNNENNIFLNNSMIQANNINKLPNDQIPQVINSYYQTNAPHPVSSNYIQPPINLPINTRSNNTYKLPQKINNRILNNLPPPCVPPNLPSDMSSNVSYNLPHKFPPNFPSNFPPNIPSNFPPNIPPGFPPNFLSNFPPNIPSEIPSSSSYSLPHKFPPNFPPNLPPNFPPNLPPNFSSNFPPNILPNFPPNLPSSMPPNLPPSMPPNLPPNLPPNLPPNLPPNLPPNLPPNSSSNSLPNQSPNLQHNGTSNVSEKVENSQSKDSDVNTNDTVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTC4</accession>
    <name>A0A1J1GTC4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00194600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527365.1">
        <property type="nucleotide sequence ID" value="XM_028670631.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730472"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00194600"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="545"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="293"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="350"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="447"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="921"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1335"/>
            <end position="1373"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1421"/>
            <end position="1451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="301"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="355"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="382"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="404"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1515" mass="179767" checksum="140CEEA15DC3192D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTD7</accession>
    <name>A0A1J1GTD7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Enoyl-CoA hydratase, putative</fullName>
            <ecNumber evidence="3">4.2.1.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00296600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.17" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528562.1">
        <property type="nucleotide sequence ID" value="XM_028671961.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTD7"/>
    <dbReference type="GeneID" id="39731499"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00296600"/>
    <dbReference type="OMA" id="CNTIQHL"/>
    <dbReference type="OrthoDB" id="410701at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004300">
        <property type="term" value="F:enoyl-CoA hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF171">
        <property type="entry name" value="SD19268P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="325"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="392" mass="46616" checksum="BD156DF0D4456DD0" modified="2017-02-15" version="1">MIKKFLNIVSNKRILRIIKENEKCDYKLIGYKKNFNCFHTINVIDENKENSCFTKHKYVDFFRDETRNIGIITFKNINDKINIFHEFLDELKNVIEHINNIISNEENNTFYIKEFKNKDNYLIKNIKNRIPYYDNKLKIIIINSIINDNTFLNSLDYNSYLKNDEETNSNISNSFRYLCNNIQNLPLITISNINGLCINSGIDLILSTDFRISNEKSKFGFDKTYIGLFPYGGSTQKLFRNIQMNYSKYLLLTNQVINANDALKMNLIDVCLRNNENFFIDNSNVFFENNLSHKEKFSILKENIIEYFQDIFKNKTFEMKIDDDSFIFTLFFSFQFLFIPTYILQNTKLSINEGISLIDVNSYLDYDKNIFEKNINSSQRLDILNYIKKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTE5</accession>
    <name>A0A1J1GTE5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein kinase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00300000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528596.1">
        <property type="nucleotide sequence ID" value="XM_028672000.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731533"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00300000"/>
    <dbReference type="OrthoDB" id="341578at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RWD" evidence="3">
        <location>
            <begin position="93"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="675"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="870"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1206"/>
            <end position="1239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1347"/>
            <end position="1571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1756"/>
            <end position="1778"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1799"/>
            <end position="1818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="870"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="890"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1230"/>
            <end position="1239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1347"/>
            <end position="1374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1389"/>
            <end position="1405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1406"/>
            <end position="1421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1429"/>
            <end position="1458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1466"/>
            <end position="1482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1490"/>
            <end position="1514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1522"/>
            <end position="1571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2339" mass="280623" checksum="2BC7A790482D2BFE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTE6</accession>
    <name>A0A1J1GTE6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00196900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527389.1">
        <property type="nucleotide sequence ID" value="XM_028670659.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730496"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00196900"/>
    <dbReference type="OMA" id="FYINYFF"/>
    <dbReference type="OrthoDB" id="5538672at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1302"/>
            <end position="1318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1450"/>
            <end position="1473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1083"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1715"/>
            <end position="1742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1083"/>
            <end position="1095"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2713" mass="328087" checksum="F1B3273AB27EA3C0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTG3</accession>
    <name>A0A1J1GTG3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">CCAAT-binding transcription factor, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00198700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NFYC/HAP5 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527405.1">
        <property type="nucleotide sequence ID" value="XM_028670676.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTG3"/>
    <dbReference type="GeneID" id="39730514"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00198700"/>
    <dbReference type="OMA" id="MITNDSR"/>
    <dbReference type="OrthoDB" id="1272441at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22908">
        <property type="entry name" value="HFD_NFYC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000062">
        <property type="entry name" value="Nuclear transcription factor Y subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050568">
        <property type="entry name" value="Transcr_DNA_Rep_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252">
        <property type="entry name" value="HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252:SF8">
        <property type="entry name" value="NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0010">Activator</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="9">
        <location>
            <begin position="14"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="167"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="527"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="167"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG94590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="730" mass="84053" checksum="36EE43E056E726D8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTL4</accession>
    <name>A0A1J1GTL4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcription initiation TFIID-like, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00300300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528599.1">
        <property type="nucleotide sequence ID" value="XM_028672003.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTL4"/>
    <dbReference type="GeneID" id="39731536"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00300300"/>
    <dbReference type="OMA" id="FANCIYN"/>
    <dbReference type="OrthoDB" id="2127950at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="entry name" value="TATA-Binding Protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000814">
        <property type="entry name" value="TBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10126">
        <property type="entry name" value="TATA-BOX BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00352">
        <property type="entry name" value="TBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55945">
        <property type="entry name" value="TATA-box binding protein-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="258"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="89"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="229"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="89"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="376" mass="43468" checksum="89FAE5098ACF8903" modified="2017-02-15" version="1">MCNPSKKTKLNNNEINNIFIKNENNMSVHNISMNAVLCSSLNLDSIYKYFSNCIYNPREFKCMRIDVPVSIKTVKKYVNYMNNKKERDDKYKLKDEKQEKINEKHSKNEEEKKDNNVNNNIKNNDIKNNDIENEKAKCEKKKEVIFNDKIIDNNKDSMKINENIVKDISICEKENISNNTNEDISDTKNDTTNYIIENITDNDVINKKLIINVSIFSNGKIICTGNNSIEACKIAMKKIEKKLKQLNFKNIKLKKITITNILAVYNVGFSIVLPLFAQYYKSVDYDPNVFPACKVKIALVNDNEKNYDGKHEENNSQYAWWSIKSTAEKEKNKVDIISASIFSTGNITLTGGKSYENLQKCIEILLPYLIKSKSQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTR5</accession>
    <name>A0A1J1GTR5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Inner membrane complex protein 1l, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">IMC1l</name>
        <name evidence="1" type="ORF">PGAL8A_00288600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528497.1">
        <property type="nucleotide sequence ID" value="XM_028671890.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTR5"/>
    <dbReference type="GeneID" id="39731419"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00288600"/>
    <dbReference type="OMA" id="YDVPQFC"/>
    <dbReference type="OrthoDB" id="376921at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="390" mass="46509" checksum="39F6B497A35693AD" modified="2017-02-15" version="1">MKSSNNIPIEFNCENFGLKNFPVVGYPLNVYKGNFKNPIYKRDIRRQFQSNPIIVKKCSSPTFFKVPRYRLNYAHKKVPVPVFHKIPKIVEIPEIREITKFVDSVKVVDVPVEQVRIIPKLKIREIEKVRHVPGPVEYIDIPQEHIVHKPYTEVVEKIYEIPEIEDIEIEVPIYVPTPIGPPKDIHINIPLPYDVPQFCFKPDKSIPPTISFPEFHNMNNIPNIYFQNERFRENSPKVDISRKHKKVMYSSPPIEYSIKNKKINENNANENFYNYNQQNFDKIPKENIYYNKYNINYDNISNTQYIPEKNNNDSSPNQNEKYYYSYSSYNKYDENNTEKNIHNDNYNKIDYSNNYENNKNYIYDEYEDKNGYDKNIIAELIVQKKKILHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU60</accession>
    <name>A0A1J1GU60_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Magnesium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00299100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Mitochondrion inner membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528587.1">
        <property type="nucleotide sequence ID" value="XM_028671990.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU60"/>
    <dbReference type="GeneID" id="39731524"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00299100"/>
    <dbReference type="OrthoDB" id="10251508at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12823">
        <property type="entry name" value="Mrs2_Mfm1p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.340:FF:000019">
        <property type="entry name" value="CorA-like Mg2+ transporter protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039204">
        <property type="entry name" value="MRS2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13890:SF0">
        <property type="entry name" value="MAGNESIUM TRANSPORTER MRS2 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13890">
        <property type="entry name" value="RNA SPLICING PROTEIN MRS2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22099">
        <property type="entry name" value="MRS2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="413"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="443"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG95779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="472" mass="55868" checksum="1982749448FA0982" modified="2017-02-15" version="1">MMPQEKKLNKPLLNINDEEEDIRKYDKNEEYNSRMGVLSNFHLNHDMKKLMKRNEIKINNENVYTDYLKSKFKSNSNSNNKNYDSILDEEKSKASKEFFFNKNTFSYMKENRGEYLKNDDFKVRIKCFNKYLKHDVHKIYNGENIQYSLQTHELLKMVHQIKGENTSINSTSGLAQYRDIRQLVSNNTNTRFDISPKRNCVLLNLPYRKCIIFKDFLLYIPTFTNSPILEVTQKEEKMCKYFIENAKVISLIKDSLPFEILILEAIFVDICEELKNEIEPVICEAEKLFEIISNNLSIYKCINKLTEMRRKLKIIDEKVQSVYKSIHGVLNNDEDVRRLEVSYFWDKPDLWEKCDPTPNNEDTEMLLEYYCHEIEEFIKIIHRTDQSLDDVLQMVELNLDDARNNVLKLELGLKIYGIIITVVGTVAAIFGMNLKNGFESDQYVFWILAFSLMLITVFCLFYVMVSFKKVNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU78</accession>
    <name>A0A1J1GU78_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic</fullName>
            <ecNumber evidence="7">1.1.1.267</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="primary">DXR</name>
        <name evidence="22" type="ORF">PGAL8A_00226700</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>2-C-methyl-D-erythritol 4-phosphate + NADP(+) = 1-deoxy-D-xylulose 5-phosphate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13717"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
            <dbReference type="ChEBI" id="CHEBI:58262"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.267"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="16">
            <dbReference type="Rhea" id="RHEA:13719"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 1/6.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Plastid</location>
            <location evidence="3">Apicoplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DXR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.267" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527685.1">
        <property type="nucleotide sequence ID" value="XM_028670987.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU78"/>
    <dbReference type="GeneID" id="39730794"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00226700"/>
    <dbReference type="OMA" id="AHPNWVM"/>
    <dbReference type="OrthoDB" id="3482at2759"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00092"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020011">
        <property type="term" value="C:apicoplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030604">
        <property type="term" value="F:1-deoxy-D-xylulose-5-phosphate reductoisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070402">
        <property type="term" value="F:NADPH binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051484">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000045">
        <property type="entry name" value="1-deoxy-D-xylulose 5-phosphate reductoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1740.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00183">
        <property type="entry name" value="DXP_reductoisom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003821">
        <property type="entry name" value="DXP_reductoisomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013644">
        <property type="entry name" value="DXP_reductoisomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013512">
        <property type="entry name" value="DXP_reductoisomerase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026877">
        <property type="entry name" value="DXPR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036169">
        <property type="entry name" value="DXPR_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00243">
        <property type="entry name" value="Dxr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30525">
        <property type="entry name" value="1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30525:SF0">
        <property type="entry name" value="1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08436">
        <property type="entry name" value="DXP_redisom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02670">
        <property type="entry name" value="DXP_reductoisom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13288">
        <property type="entry name" value="DXPR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69055">
        <property type="entry name" value="1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0933">Apicoplast</keyword>
    <keyword evidence="15" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="14" id="KW-0464">Manganese</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0521">NADP</keyword>
    <keyword evidence="13 22" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-0934">Plastid</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="18" id="KW-0732">Signal</keyword>
    <keyword evidence="12" id="KW-0809">Transit peptide</keyword>
    <feature type="signal peptide" evidence="18">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012520568" description="1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic" evidence="18">
        <location>
            <begin position="21"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="1-deoxy-D-xylulose 5-phosphate reductoisomerase N-terminal" evidence="19">
        <location>
            <begin position="77"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal" evidence="20">
        <location>
            <begin position="224"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="DXP reductoisomerase C-terminal" evidence="21">
        <location>
            <begin position="354"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00073770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF02670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF08436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF13288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="CRG94870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="484" mass="55506" checksum="BEDF8BC626A03DEC" modified="2017-02-15" version="1">MVIFIYLYILLVLEINYLFSKNASKKTLYKITYINNALKGLGKRKTEKLKNIKSYINVKLLKSNFIDITNSKKQINIGIFGSTGSIGRNTLDIIKECNQIEKIFNVEALYVNKNVKDLYEQAKEFLPKYICIHDETKYEELKNLLLNIKNYHPTILIGDEGMKTICNDNTIDKIVIGIDSFQGIYSTIYAIKNNKIVALANKESIVSAGFFLKKLLNVNKNSFVIPVDSEHSAIFQCLDNNKVLKTKCLQDNFSKINNINKIFLCSSGGPFQNISLNELKNVTSANALKHPKWTMGKKITIDSATMMNKGLEVIETHFLFDVNYDNIEVIVHKECIIHSCVEFVDKSVISQMYYPDMKIPILYALTWPNRIKTNLKPLNLVETSPLTFYKPSLDKFPCIKLAYHAGKKGNFFPTVLNASNEICNNLFLNDKIKYFDISAIISQVLESFQIQKVSENSEDLMNQIFEIHNWSKKKAMDIYKKGNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU82</accession>
    <name>A0A1J1GU82_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00328400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000056">
        <property type="protein sequence ID" value="CRG96071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528876.1">
        <property type="nucleotide sequence ID" value="XM_028672312.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731814"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00328400"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="834"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="369"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="581"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1212"/>
            <end position="1275"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2048"/>
            <end position="2075"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="370"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="392"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="408"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="443"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="468"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="494"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="522"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2131" mass="250331" checksum="493C665514202507" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUW1</accession>
    <name>A0A1J1GUW1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GPI transamidase component GPI16, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">GPI16</name>
        <name evidence="3" type="ORF">PGAL8A_00348700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529074.1">
        <property type="nucleotide sequence ID" value="XM_028672530.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUW1"/>
    <dbReference type="GeneID" id="39732017"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00348700"/>
    <dbReference type="OMA" id="ITEHDHK"/>
    <dbReference type="OrthoDB" id="331263at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042765">
        <property type="term" value="C:GPI-anchor transamidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016255">
        <property type="term" value="P:attachment of GPI anchor to protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007245">
        <property type="entry name" value="PIG-T"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12959:SF11">
        <property type="entry name" value="GPI TRANSAMIDASE COMPONENT PIG-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12959">
        <property type="entry name" value="GPI TRANSAMIDASE COMPONENT PIG-T-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04113">
        <property type="entry name" value="Gpi16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012023500" evidence="2">
        <location>
            <begin position="21"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="482"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="513" mass="60339" checksum="4DC6FD97BB209A1F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV30</accession>
    <name>A0A1J1GV30_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin-like protein ATG12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ATG12</name>
        <name evidence="5" type="ORF">PGAL8A_00229500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">Forms a conjugate with ATG5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ATG12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527712.1">
        <property type="nucleotide sequence ID" value="XM_028671017.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV30"/>
    <dbReference type="GeneID" id="39730822"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00229500"/>
    <dbReference type="OMA" id="EHIYLYI"/>
    <dbReference type="OrthoDB" id="10003551at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034274">
        <property type="term" value="C:Atg12-Atg5-Atg16 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000421">
        <property type="term" value="C:autophagosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019776">
        <property type="term" value="F:Atg8-family ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097352">
        <property type="term" value="P:autophagosome maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061723">
        <property type="term" value="P:glycophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01612">
        <property type="entry name" value="Ubl_ATG12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007242">
        <property type="entry name" value="Atg12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13385">
        <property type="entry name" value="AUTOPHAGY PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13385:SF0">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEIN ATG12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04110">
        <property type="entry name" value="APG12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0072">Autophagy</keyword>
    <keyword evidence="1 4" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0833">Ubl conjugation pathway</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="111" mass="13197" checksum="2F58411D34F8AA7B" modified="2017-02-15" version="1">MPDKIYYFPHFIKKPDMRESLTLRRNKKVKVVFRNISGATLLKKNKILINGNETFASILNFLQKIFNKNENIYLYINNAIKPNLDDFIYDLYELYKISDSLNISYSFTPAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV67</accession>
    <name>A0A1J1GV67_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cilia- and flagella-associated protein 52</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00259700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
            <location evidence="1">Flagellum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the CFAP52 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528005.1">
        <property type="nucleotide sequence ID" value="XM_028671343.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV67"/>
    <dbReference type="GeneID" id="39731126"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00259700"/>
    <dbReference type="OMA" id="RIMVYNF"/>
    <dbReference type="OrthoDB" id="6252103at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031514">
        <property type="term" value="C:motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050630">
        <property type="entry name" value="WD_repeat_EMAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720:SF14">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720">
        <property type="entry name" value="WD-40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="672"/>
            <end position="705"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG95193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="713" mass="84502" checksum="B4C576E7578A7841" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVB1</accession>
    <name>A0A1J1GVB1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00368800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529268.1">
        <property type="nucleotide sequence ID" value="XM_028672746.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732218"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00368800"/>
    <dbReference type="OMA" id="ENLCAIM"/>
    <dbReference type="OrthoDB" id="372199at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="391"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="496"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="667"/>
            <end position="723"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="936" mass="111201" checksum="88418A1FAA355AC4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVR6</accession>
    <name>A0A1J1GVR6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Transporter, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00356800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC43A transporter (TC 2.A.1.44) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529155.1">
        <property type="nucleotide sequence ID" value="XM_028672620.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVR6"/>
    <dbReference type="GeneID" id="39732098"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00356800"/>
    <dbReference type="OMA" id="RYVCEDQ"/>
    <dbReference type="OrthoDB" id="330047at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052599">
        <property type="entry name" value="SLC43A_AATransporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20772">
        <property type="entry name" value="PROTEIN FMP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20772:SF2">
        <property type="entry name" value="PROTEIN FMP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="138"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="225"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="260"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="379"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="445"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="468"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="504"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="535"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG96350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="574" mass="66039" checksum="70BDDFE4492BD066" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVS9</accession>
    <name>A0A1J1GVS9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytosolic Fe-S cluster assembly factor NBP35, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00423600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529460.1">
        <property type="nucleotide sequence ID" value="XM_028672959.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVS9"/>
    <dbReference type="GeneID" id="39732768"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00423600"/>
    <dbReference type="OMA" id="DEHITIC"/>
    <dbReference type="OrthoDB" id="1741334at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140663">
        <property type="term" value="F:ATP-dependent FeS chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02037">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02040">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000808">
        <property type="entry name" value="Mrp-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019591">
        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23264:SF19">
        <property type="entry name" value="CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR NUBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23264">
        <property type="entry name" value="NUCLEOTIDE-BINDING PROTEIN NBP35 YEAST -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01215">
        <property type="entry name" value="MRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="367"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="383"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="431" mass="49015" checksum="FEB65290BB11E7EB" modified="2017-02-15" version="1">MNAYTKKNLITFLLGSLAGLTFSYVLIERRKLLEYLINGFKILKNIKIKNKKNSAVAIPEECPGIDNENAGKSKICEGCPNRKICNDPELKKEKEKEKNKAFNEIKENLKNVKCKILILSGKGGVGKSTVAAQIAFALSYLNYDVGLLDIDICGPSIPILTKTINYDVNYSMNGWIPIYKNNLSIMSVGYLLPNFDDPVIWRGPKKNGLIKQFLCDVYWKNLDFLIIDTPPGTSDEHLTICSYLKDNLDGCLIVTTPHILSICDVKKEIEFCKKTNIPILGIIENMYQSIFISNYTVEKMCSEMSVPYSGKVTFHQNLIEACQKGIGCCDIDPYSPSSREIFFLCKFFIEQILKKYTHQLNETNENPSLKDDKIHINNSENQKNIKEENNGDDKMSNKFNSISCVEENLTKIQMLNKLINEINLYIEEKNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVW3</accession>
    <name>A0A1J1GVW3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pseudouridylate synthase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00426800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529492.1">
        <property type="nucleotide sequence ID" value="XM_028672995.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVW3"/>
    <dbReference type="GeneID" id="39732800"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00426800"/>
    <dbReference type="OrthoDB" id="424794at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluA-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050188">
        <property type="entry name" value="RluA_PseudoU_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600">
        <property type="entry name" value="MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600:SF40">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE RPUSD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012520576" evidence="2">
        <location>
            <begin position="17"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="domain" description="Pseudouridine synthase RsuA/RluA-like" evidence="3">
        <location>
            <begin position="356"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="767" mass="91504" checksum="AAB433F0CF21A3FD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW04</accession>
    <name>A0A1J1GW04_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Small nuclear ribonucleoprotein Sm D3</fullName>
            <shortName evidence="9">Sm-D3</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">snRNP core protein D3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">SNRPD3</name>
        <name evidence="11" type="ORF">PGAL8A_00422600</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the snRNP core protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529450.1">
        <property type="nucleotide sequence ID" value="XM_028672948.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW04"/>
    <dbReference type="GeneID" id="39732758"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00422600"/>
    <dbReference type="OMA" id="CQMSAIT"/>
    <dbReference type="OrthoDB" id="6425924at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01721">
        <property type="entry name" value="Sm_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000002">
        <property type="entry name" value="Small nuclear ribonucleoprotein Sm D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027141">
        <property type="entry name" value="LSm4/Sm_D1/D3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034099">
        <property type="entry name" value="SmD3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23338">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9 11" id="KW-0687">Ribonucleoprotein</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="5"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG96646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="116" mass="12997" checksum="ADD7B0CC63AD3752" modified="2017-02-15" version="1">MSVGVPIKLLHEGIGHTISVETQSGVLYRGTLLFAEDNMNCLLENVSVVKKDGKQILLEQVYIRGGSVCFMIFPDMLRYAPIFKINKSKTKTNFATIRRAMEVHARIASKNKDIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW26</accession>
    <name>A0A1J1GW26_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein farnesyltransferase subunit beta</fullName>
            <ecNumber evidence="3">2.5.1.58</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">CAAX farnesyltransferase subunit beta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Ras proteins prenyltransferase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00374900</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein prenyltransferase subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.58" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529329.1">
        <property type="nucleotide sequence ID" value="XM_028672814.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW26"/>
    <dbReference type="GeneID" id="39732279"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00374900"/>
    <dbReference type="OrthoDB" id="10261146at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005965">
        <property type="term" value="C:protein farnesyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004660">
        <property type="term" value="F:protein farnesyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02893">
        <property type="entry name" value="FTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026872">
        <property type="entry name" value="FTB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045089">
        <property type="entry name" value="PGGT1B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001330">
        <property type="entry name" value="Prenyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774:SF6">
        <property type="entry name" value="PROTEIN FARNESYLTRANSFERASE SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00432">
        <property type="entry name" value="Prenyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Prenyltransferase alpha-alpha toroid" evidence="12">
        <location>
            <begin position="451"/>
            <end position="918"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG96524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="958" mass="113524" checksum="9AA46F2F81631112" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW27</accession>
    <name>A0A1J1GW27_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00262400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528032.1">
        <property type="nucleotide sequence ID" value="XM_028671373.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW27"/>
    <dbReference type="GeneID" id="39731153"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00262400"/>
    <dbReference type="OMA" id="YMDSIVK"/>
    <dbReference type="OrthoDB" id="431202at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022127">
        <property type="entry name" value="STIMATE/YPL162C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31735">
        <property type="entry name" value="VACUOLAR MEMBRANE PROTEIN YPL162C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31735:SF1">
        <property type="entry name" value="VACUOLAR MEMBRANE PROTEIN YPL162C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12400">
        <property type="entry name" value="STIMATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="312"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="354"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="391" mass="46251" checksum="E1068AF68B2537FA" modified="2017-02-15" version="1">MKEQCLLVPGEFGIIVQIFIGCVSLSVLLTKYILENPRRSFITFLKDLISILCGSVILHSVNIFISILIFRCNILLYLCNIDMDECSIYFIQIIIDATFGLYLEYKIFPIYKFIKIRREYLYNNSNGSIYKPIDALSHYSSFLNLTEKNNKKGFDDKYNINSKNNLNIFKLIFFNFKKYLGKKKYNFFSKNKTKNLEDHNGTANIFEEKIFKQDIIFNGDHIFYNFTTNEKIDNKKQTNEKSLRIYNDDDDDDKNELTLLNDKTKNKEFSIQLNENILFDYDDIIIYENKNLDIYKEIDENYSNLSIFHGTILWISVVLTAKCVTLLSFFLLSPIFNIFVLYTLSLINDMKFKLLIVMVILPFFLNFIIYFFTDSIIKTKNTYININYDKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW95</accession>
    <name>A0A1J1GW95_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="26">Dynein heavy chain, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="26" type="ORF">PGAL8A_00417800</name>
    </gene>
    <organism evidence="26 27">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="26" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="26">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynein heavy chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="26">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529401.1">
        <property type="nucleotide sequence ID" value="XM_028672894.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732709"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00417800"/>
    <dbReference type="OMA" id="MGMVFMS"/>
    <dbReference type="OrthoDB" id="424310at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097729">
        <property type="term" value="C:9+2 motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036157">
        <property type="term" value="C:outer dynein arm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008569">
        <property type="term" value="F:minus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060294">
        <property type="term" value="P:cilium movement involved in cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036158">
        <property type="term" value="P:outer dynein arm assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001221">
        <property type="entry name" value="Axonemal dynein heavy chain 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.710:FF:000003">
        <property type="entry name" value="Dynein axonemal heavy chain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.100:FF:000001">
        <property type="entry name" value="dynein heavy chain 17, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000738">
        <property type="entry name" value="Dynein heavy chain axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.1220:FF:000005">
        <property type="entry name" value="Dynein heavy chain, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1120:FF:000009">
        <property type="entry name" value="Dynein heavy chain, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.490.20:FF:000010">
        <property type="entry name" value="Dynein heavy chain, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.180.20:FF:000005">
        <property type="entry name" value="Dynein heavy chain, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001194">
        <property type="entry name" value="Dynein heavy chain, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001310">
        <property type="entry name" value="Dynein heavy chain, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001375">
        <property type="entry name" value="Dynein heavy chain, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.20:FF:000009">
        <property type="entry name" value="Putative dynein heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.100">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.180.20">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.720">
        <property type="entry name" value="Region D6 of dynein motor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035699">
        <property type="entry name" value="AAA_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035706">
        <property type="entry name" value="AAA_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041658">
        <property type="entry name" value="AAA_lid_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042219">
        <property type="entry name" value="AAA_lid_11_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041589">
        <property type="entry name" value="DNAH3_AAA_lid_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042222">
        <property type="entry name" value="Dynein_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043157">
        <property type="entry name" value="Dynein_AAA1S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041466">
        <property type="entry name" value="Dynein_AAA5_ext"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041228">
        <property type="entry name" value="Dynein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043160">
        <property type="entry name" value="Dynein_C_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024743">
        <property type="entry name" value="Dynein_HC_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024317">
        <property type="entry name" value="Dynein_heavy_chain_D4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004273">
        <property type="entry name" value="Dynein_heavy_D6_P-loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013602">
        <property type="entry name" value="Dynein_heavy_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042228">
        <property type="entry name" value="Dynein_linker_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10676:SF365">
        <property type="entry name" value="AAA+ ATPASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10676">
        <property type="entry name" value="DYNEIN HEAVY CHAIN FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12774">
        <property type="entry name" value="AAA_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12775">
        <property type="entry name" value="AAA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12780">
        <property type="entry name" value="AAA_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12781">
        <property type="entry name" value="AAA_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17857">
        <property type="entry name" value="AAA_lid_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18198">
        <property type="entry name" value="AAA_lid_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08393">
        <property type="entry name" value="DHC_N2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17852">
        <property type="entry name" value="Dynein_AAA_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18199">
        <property type="entry name" value="Dynein_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03028">
        <property type="entry name" value="Dynein_heavy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12777">
        <property type="entry name" value="MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0966">Cell projection</keyword>
    <keyword evidence="10" id="KW-0969">Cilium</keyword>
    <keyword evidence="9 14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-0243">Dynein</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="11" id="KW-0505">Motor protein</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="27" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Dynein heavy chain linker" evidence="17">
        <location>
            <begin position="1731"/>
            <end position="1851"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain linker" evidence="17">
        <location>
            <begin position="2056"/>
            <end position="2355"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain hydrolytic ATP-binding dynein motor region" evidence="18">
        <location>
            <begin position="2499"/>
            <end position="2830"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain AAA 5 extension" evidence="22">
        <location>
            <begin position="3196"/>
            <end position="3308"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain 3 AAA+ lid" evidence="23">
        <location>
            <begin position="3540"/>
            <end position="3612"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain AAA module D4" evidence="20">
        <location>
            <begin position="3775"/>
            <end position="3915"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain AAA module D4" evidence="20">
        <location>
            <begin position="3973"/>
            <end position="4105"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain coiled coil stalk" evidence="19">
        <location>
            <begin position="4119"/>
            <end position="4477"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain ATP-binding dynein motor region" evidence="21">
        <location>
            <begin position="4506"/>
            <end position="4729"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain region D6 P-loop" evidence="16">
        <location>
            <begin position="5082"/>
            <end position="5191"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain AAA lid" evidence="24">
        <location>
            <begin position="5225"/>
            <end position="5365"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain C-terminal" evidence="25">
        <location>
            <begin position="5501"/>
            <end position="5788"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="397"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="482"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1379"/>
            <end position="1420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1855"/>
            <end position="1999"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="3093"/>
            <end position="3190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="3911"/>
            <end position="3970"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="185"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="4124"/>
            <end position="4154"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="4357"/>
            <end position="4433"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="4678"/>
            <end position="4754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="397"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="408"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="421"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="439"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="483"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="498"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="1397"/>
            <end position="1410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1855"/>
            <end position="1866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1873"/>
            <end position="1893"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="1894"/>
            <end position="1911"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1912"/>
            <end position="1999"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="3094"/>
            <end position="3115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="3117"/>
            <end position="3130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="3146"/>
            <end position="3171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="3172"/>
            <end position="3181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="3939"/>
            <end position="3950"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="3951"/>
            <end position="3963"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF03028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF08393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF12774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF12777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF12780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF12781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF17852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF17857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF18198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="Pfam" id="PF18199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="EMBL" id="CRG96597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="5791" mass="683107" checksum="5C8841C7678A3BC4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWA2</accession>
    <name>A0A1J1GWA2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00433100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529554.1">
        <property type="nucleotide sequence ID" value="XM_028673063.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWA2"/>
    <dbReference type="GeneID" id="39732863"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00433100"/>
    <dbReference type="OrthoDB" id="382153at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="58"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="186" mass="22160" checksum="7F10EAB07170CA44" modified="2017-02-15" version="1">MSILYSIFPILFFFSFNKKIYGLSKIIKPHINVYYKDYSENLPSDEKDKLMKILLENDENEENENISENMNIEKMEEKEKNLEILMKEQENLSNKIYNELKGYIKRDRNISIKYVHDEEDFISEDKNNLKKDENILNVDTEINGSLDSLQAPIVMIKIPSVNIYNQFEIQRDIGKLIDLNNEELFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWQ7</accession>
    <name>A0A1J1GWQ7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Actin-related protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ARP4a</name>
        <name evidence="4" type="ORF">PGAL8A_00294600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528549.1">
        <property type="nucleotide sequence ID" value="XM_028671947.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWQ7"/>
    <dbReference type="GeneID" id="39731479"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00294600"/>
    <dbReference type="OMA" id="IAYRRCH"/>
    <dbReference type="OrthoDB" id="5132116at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="297"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="297"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="462" mass="53267" checksum="22B86DF3EADE57C0" modified="2017-02-15" version="1">MNLKNETNENVLCGGEDISALVVDLGFNTSKIGHNQEDTPRIFLNSICGENIYESERNINELEKKNNFKKLKFPLNLYNRNENVRIKPLFDRDKSNNVTLNSDVFERILEYSIEGVEVKRIFECTDEIIDPIKLGGLNLKFDEHPILLSESNIHNNKIREEITELLFEKYNVPALYFAKKAKLTSFSLGRSNSLVIDIGFSSLNINPVYEGYVLQKNSLEYNIGGDYFDKLIYNKLKKDNINIIPYFCGQKFNDKDMYKNIHSSYKEEAILDIIRYMKESVCKIRVENDIKCKENNINNLKGNENGDTNNTDTNDSPKEEFFELPDGFKINIEKYKYDIAENLFKSVPLENNFKGLPQSIINCIISTDVDIRKDLLQSVILTGGSSLFPGLVERLFNSLKEKECFSQSVKLKILNMTSLVENKYSSWLGGSILASLGTFQQLWVSKKEYLDYGHKIIFDRCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWU2</accession>
    <name>A0A1J1GWU2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PIR-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00268900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000038">
        <property type="protein sequence ID" value="CRG95487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528296.1">
        <property type="nucleotide sequence ID" value="XM_028671667.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWU2"/>
    <dbReference type="GeneID" id="39731219"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00268900"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="253"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="318" mass="36617" checksum="66FED84D3B46B181" modified="2017-02-15" version="1">MFSYSVVIVYIFFFLILIFQYFCNKSFEISNKNLNIVSNLIGARVLTEQQLSPIIRTVRSSSDIECELVELHEFIHKVLFDKSGKLSSNFTGDNTVEYTNWISNKNMDIVRALNTHPEPNNKYFLNNFVYLWSKLAEEFDVYSYVNWVYQVMLNGRIFNNKPRTIPLLSSTSPSSITPATSAVSSLVNNTLSEIITNASSISTSQLKNLTTLTPSIETETIITSENNSSLLMPVEHSNLHKAFCWFFYDPKNFIALYIPLVVVGRLLFFIYLYKQNTHTRSVLGKGNPKKKKGKRRMHKMDNGYNIHEHSEFPPIYPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX03</accession>
    <name>A0A1J1GX03_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RNA methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00304100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class IV-like SAM-binding methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528637.1">
        <property type="nucleotide sequence ID" value="XM_028672045.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX03"/>
    <dbReference type="GeneID" id="39731574"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00304100"/>
    <dbReference type="OMA" id="FFPIHKD"/>
    <dbReference type="OrthoDB" id="361029at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18086">
        <property type="entry name" value="HsC9orf114-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003750">
        <property type="entry name" value="Put_MeTrfase-C9orf114-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12150">
        <property type="entry name" value="CLASS IV SAM-BINDING METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12150:SF13">
        <property type="entry name" value="METHYLTRANSFERASE C9ORF114-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02598">
        <property type="entry name" value="Methyltrn_RNA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="445" mass="52278" checksum="FE2B4E2FC25BE167" modified="2017-02-15" version="1">MKEKEILHDKKISKKYIYKKQNKKHMNNEKKEKRKEKIKKFDNVGKNENIIVETNDSNITKNENCDDIKSHLNEYIKNSISKKIPNISRNLKIDLFVAIPSTIINNKSDVIKSYLSSYLARIFTIFSISKIYIYDDHLRNEKYVNQQRNNIISNNSYNQNENKCNNDKSDEKNSINFIRRNNDYSTNETKKEKSNEYSYLCKYLYYNLQYLETPQYLRKHLFPITNFLKNSGIMNPVDAPHHLRSDEWLPFREGVVVKRELKGIIVDVGLFTNVFIKDENFINTGTRVTVLLNSDSFKLFQKKNPKILLSGKLIHPTIPKLYNLYWGYSIEILKNVSDIFNLPVDYIIGTSERGKTIDDSILSLKDTKSILIVFGNKDGLEDLLIKEKEEKKKKNYSPEKKIKVLNKILKKFDLFINTCPFQTSRTIRTEEAISITLSLLHNILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX47</accession>
    <name>A0A1J1GX47_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Coronin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00472000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the WD repeat coronin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529942.1">
        <property type="nucleotide sequence ID" value="XM_028673495.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX47"/>
    <dbReference type="GeneID" id="39733253"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00472000"/>
    <dbReference type="OMA" id="MESRTIY"/>
    <dbReference type="OrthoDB" id="291820at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015505">
        <property type="entry name" value="Coronin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10856">
        <property type="entry name" value="CORONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10856:SF0">
        <property type="entry name" value="CORONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16300">
        <property type="entry name" value="WD40_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01167">
        <property type="entry name" value="DUF1900"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="47"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="94"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="445"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="533"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="474"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="445"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="555"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU280818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="605" mass="69484" checksum="1DC3E2117FCBEC35" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX73</accession>
    <name>A0A1J1GX73_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Merozoite surface protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00473600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000084">
        <property type="protein sequence ID" value="CRG97153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529956.1">
        <property type="nucleotide sequence ID" value="XM_028673511.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX73"/>
    <dbReference type="GeneID" id="39733269"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00473600"/>
    <dbReference type="OMA" id="DNMQPDS"/>
    <dbReference type="OrthoDB" id="392935at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0477">Merozoite</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="435"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="506"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="542"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="585"/>
            <end position="597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="633" mass="70488" checksum="31B421D990EA032F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXA1</accession>
    <name>A0A1J1GXA1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00468400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529906.1">
        <property type="nucleotide sequence ID" value="XM_028673456.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXA1"/>
    <dbReference type="GeneID" id="39733217"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00468400"/>
    <dbReference type="OMA" id="NDYFKCF"/>
    <dbReference type="OrthoDB" id="386224at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010995">
        <property type="entry name" value="DNA_repair_Rad51/TF_NusA_a-hlx"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47794">
        <property type="entry name" value="Rad51 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="319" mass="39006" checksum="FA84526A679A90D6" modified="2017-02-15" version="1">MQTKIEKIYYPKDEIKNDIFFKKEDDNFYARKKKNNEKSNILRKHNKSEKHEKIFCGNLKDIKIDCDNFKNEKDNYNNFFDSKIYLPELRASKEELKYFFKIICIMLEKNKKENIYVNLMNFLCKNFSIYIGLFANLWFQCKILLAEKLILIEFFKQLKINSEIINHFFNYGYDSFETILSITPQDLIKIQKFNNVTWIPGHAFRIKIIFSKINDYFKCFYEKNEDYIKEMKKFILHNRRKTKLTNQLILTQEKKNKRDKTDISPCTPTKKNVIKNYEPYISLKLKNENSIHNNQLYRNIPLLKYYQYCPYYKFHKNKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXG4</accession>
    <name>A0A1J1GXG4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytoadherence linked asexual protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00475400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529978.1">
        <property type="nucleotide sequence ID" value="XM_028673536.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733287"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00475400"/>
    <dbReference type="OMA" id="LMHDLNW"/>
    <dbReference type="OrthoDB" id="382618at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020035">
        <property type="term" value="P:adhesion of symbiont to microvasculature"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005553">
        <property type="entry name" value="CLAG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03805">
        <property type="entry name" value="CLAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="250"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1115"/>
            <end position="1132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1171"/>
            <end position="1193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1326" mass="158347" checksum="A5229D1152A7FC67" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXS7</accession>
    <name>A0A1J1GXS7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00484000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530063.1">
        <property type="nucleotide sequence ID" value="XM_028673629.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXS7"/>
    <dbReference type="GeneID" id="39733373"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00484000"/>
    <dbReference type="OMA" id="LERSKYW"/>
    <dbReference type="OrthoDB" id="416353at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="512" mass="61811" checksum="4774E15ECFB504D9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY23</accession>
    <name>A0A1J1GY23_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Enhancer of rudimentary homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ERH</name>
        <name evidence="3" type="ORF">PGAL8A_00496300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">May have a role in the cell cycle.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the E(R) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530186.1">
        <property type="nucleotide sequence ID" value="XM_028673767.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY23"/>
    <dbReference type="GeneID" id="39733496"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00496300"/>
    <dbReference type="OMA" id="ESRTWSD"/>
    <dbReference type="OrthoDB" id="7887808at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2260.10">
        <property type="entry name" value="Enhancer of rudimentary"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035912">
        <property type="entry name" value="EHR_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000781">
        <property type="entry name" value="ERH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12373">
        <property type="entry name" value="ENHANCER OF RUDIMENTARY ERH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12373:SF0">
        <property type="entry name" value="ENHANCER OF RUDIMENTARY HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01133">
        <property type="entry name" value="ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016393">
        <property type="entry name" value="Enh_rudimentary"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143875">
        <property type="entry name" value="ERH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR016393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="105" mass="12549" checksum="E22FB906479FBB2F" modified="2017-02-15" version="1">MNPSYSDVVLLVQFSRKIESRTFVEYNSLKLALNGICQLYEQAIKENDPSVQRITYNMNDLFLYIDNIQKMTLLLFHQPTWTYKPHDKKWIKQKLVEHIKDQIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY86</accession>
    <name>A0A1J1GY86_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00480300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530027.1">
        <property type="nucleotide sequence ID" value="XM_028673590.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733336"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00480300"/>
    <dbReference type="OMA" id="CYMNKLL"/>
    <dbReference type="OrthoDB" id="375802at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031431">
        <property type="term" value="C:Dbf4-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043539">
        <property type="term" value="F:protein serine/threonine kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010571">
        <property type="term" value="P:positive regulation of nuclear cell cycle DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901987">
        <property type="term" value="P:regulation of cell cycle phase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051590">
        <property type="entry name" value="Replication_Regulatory_Kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15375">
        <property type="entry name" value="ACTIVATOR OF S-PHASE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15375:SF26">
        <property type="entry name" value="PROTEIN CHIFFON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1521" mass="184089" checksum="C7285175B92E3995" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYA1</accession>
    <name>A0A1J1GYA1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF4536 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00347400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529061.1">
        <property type="nucleotide sequence ID" value="XM_028672516.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYA1"/>
    <dbReference type="GeneID" id="39732004"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00347400"/>
    <dbReference type="OMA" id="NSEDCIF"/>
    <dbReference type="OrthoDB" id="6604875at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="78" mass="8923" checksum="1B61AF42305AB023" modified="2017-02-15" version="1">MFTVSKKNSEDCIFCRITGTIIFGSVSFYSFLKFLQAEKKSGDKRFFGFISICFSFLALYRATNPAKSLLNKENKNVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYF4</accession>
    <name>A0A1J1GYF4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Deoxyuridine 5'-triphosphate nucleotidohydrolase</fullName>
            <shortName evidence="5">dUTPase</shortName>
            <ecNumber evidence="5">3.6.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">dUTP pyrophosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">dUTPase</name>
        <name evidence="7" type="ORF">PGAL8A_00353800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in nucleotide metabolism via production of dUMP, the immediate precursor of thymidine nucleotides, and decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>dUTP + H2O = dUMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10248"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61555"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="3.6.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 5">Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the dUTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.23" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529125.1">
        <property type="nucleotide sequence ID" value="XM_028672587.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYF4"/>
    <dbReference type="GeneID" id="39732068"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00353800"/>
    <dbReference type="OMA" id="MHLKIMC"/>
    <dbReference type="OrthoDB" id="419889at2759"/>
    <dbReference type="UniPathway" id="UPA00610">
        <property type="reaction ID" value="UER00666"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004170">
        <property type="term" value="F:dUTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006226">
        <property type="term" value="P:dUMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046081">
        <property type="term" value="P:dUTP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07557">
        <property type="entry name" value="trimeric_dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008181">
        <property type="entry name" value="dUTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029054">
        <property type="entry name" value="dUTPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036157">
        <property type="entry name" value="dUTPase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033704">
        <property type="entry name" value="dUTPase_trimeric"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11241">
        <property type="entry name" value="DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11241:SF0">
        <property type="entry name" value="DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00692">
        <property type="entry name" value="dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51283">
        <property type="entry name" value="dUTPase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="dUTPase-like" evidence="6">
        <location>
            <begin position="83"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="169" mass="19000" checksum="3DA852AF3C9A4CCA" modified="2017-02-15" version="1">MHLKIKCLSDEVRELYKNHKTYHEGDSGLDLFIIKDEVIKAKSTTFVKLGIKVVALQYKCDCYNKCCEKNKKDDTKNVINTSFLLFPRSSISKTPLRLANSIGLIDAGYRGEIIAALDNISEDDYHIKKNDKLVQLVSFTGEPLSFELVDELDETSRGEGGFGSTSNNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYF9</accession>
    <name>A0A1J1GYF9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">WD-repeat protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00493000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530153.1">
        <property type="nucleotide sequence ID" value="XM_028673729.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYF9"/>
    <dbReference type="GeneID" id="39733463"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00493000"/>
    <dbReference type="OMA" id="NNNILCC"/>
    <dbReference type="OrthoDB" id="10264376at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051858">
        <property type="entry name" value="WD_repeat_GAD-1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16017">
        <property type="entry name" value="GASTRULATION DEFECTIVE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16017:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="75"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="174"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="283"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="33"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="652" mass="76522" checksum="985004D7A707DBCE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYP9</accession>
    <name>A0A1J1GYP9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00364900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529229.1">
        <property type="nucleotide sequence ID" value="XM_028672703.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732179"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00364900"/>
    <dbReference type="OrthoDB" id="384619at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1779" mass="214305" checksum="09C3B4A0AB46EE99" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYT7</accession>
    <name>A0A1J1GYT7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00497600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000100">
        <property type="protein sequence ID" value="CRG97401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530203.1">
        <property type="nucleotide sequence ID" value="XM_028673785.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYT7"/>
    <dbReference type="GeneID" id="39733509"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00497600"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="560"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="735"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="735" mass="91369" checksum="3A1360A96EF3FDE2" modified="2017-02-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYX0</accession>
    <name>A0A1J1GYX0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Dynamin-like protein, putative</fullName>
            <ecNumber evidence="7">3.6.5.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">DYN1</name>
        <name evidence="7" type="ORF">PGAL8A_00372900</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.5" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529309.1">
        <property type="nucleotide sequence ID" value="XM_028672792.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYX0"/>
    <dbReference type="GeneID" id="39732259"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00372900"/>
    <dbReference type="OMA" id="MAFRYVK"/>
    <dbReference type="OrthoDB" id="5061070at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001311">
        <property type="entry name" value="Dynamin-like protein-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1240">
        <property type="entry name" value="Dynamin, middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019762">
        <property type="entry name" value="Dynamin_GTPase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003130">
        <property type="entry name" value="GED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF233">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_59, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02212">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00302">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00410">
        <property type="entry name" value="G_DYNAMIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="6">
        <location>
            <begin position="23"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="GED" evidence="5">
        <location>
            <begin position="595"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="520"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="783"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="526"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="536"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="789"/>
            <end position="803"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="813" mass="93941" checksum="FA3C32641AAAA7A0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ32</accession>
    <name>A0A1J1GZ32_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00025600</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530621.1">
        <property type="nucleotide sequence ID" value="XM_028674249.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ32"/>
    <dbReference type="GeneID" id="39728779"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00025600"/>
    <dbReference type="OMA" id="EHTMQRF"/>
    <dbReference type="OrthoDB" id="4255at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00268">
        <property type="entry name" value="DEADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001060">
        <property type="entry name" value="ATP-dependent RNA helicase RhlE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059027">
        <property type="entry name" value="DD_DDX21-DDX50"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044742">
        <property type="entry name" value="DEAD/DEAH_RhlB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012562">
        <property type="entry name" value="GUCT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26142">
        <property type="entry name" value="DD_DDX21-DDX50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08152">
        <property type="entry name" value="GUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="170"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="390"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG97821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="721" mass="83796" checksum="55C745E05C1C5B25" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ42</accession>
    <name>A0A1J1GZ42_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SUN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00529700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530521.1">
        <property type="nucleotide sequence ID" value="XM_028674138.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ42"/>
    <dbReference type="GeneID" id="39733830"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00529700"/>
    <dbReference type="OrthoDB" id="342281at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043495">
        <property type="term" value="F:protein-membrane adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045119">
        <property type="entry name" value="SUN1-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012919">
        <property type="entry name" value="SUN_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12911:SF8">
        <property type="entry name" value="KLAROID PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12911">
        <property type="entry name" value="SAD1/UNC-84-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07738">
        <property type="entry name" value="Sad1_UNC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51469">
        <property type="entry name" value="SUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="SUN" evidence="8">
        <location>
            <begin position="591"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="390"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="214"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="401"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG97720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="808" mass="95476" checksum="27DBB04B8C6C515F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ77</accession>
    <name>A0A1J1GZ77_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA-directed RNA polymerase subunit</fullName>
            <ecNumber evidence="6">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">RNAPI</name>
        <name evidence="9" type="ORF">PGAL8A_00030500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the RNA polymerase beta' chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530669.1">
        <property type="nucleotide sequence ID" value="XM_028674302.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728828"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00030500"/>
    <dbReference type="OMA" id="MGRSIDM"/>
    <dbReference type="OrthoDB" id="270392at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.40.20:FF:000019">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.180">
        <property type="entry name" value="RNA polymerase ii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.120">
        <property type="entry name" value="RNA polymerase II, clamp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="entry name" value="RNA polymerase Rpb1, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006592">
        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007080">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007083">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044893">
        <property type="entry name" value="RNA_pol_Rpb1_clamp_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038120">
        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376:SF11">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04997">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05000">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4 6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNA polymerase N-terminal" evidence="8">
        <location>
            <begin position="511"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="855"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2073"/>
            <end position="2295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2350"/>
            <end position="2405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="857"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="2073"/>
            <end position="2084"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="2091"/>
            <end position="2113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="2115"/>
            <end position="2146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="2147"/>
            <end position="2161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="2169"/>
            <end position="2190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="2191"/>
            <end position="2204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="2205"/>
            <end position="2222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="2223"/>
            <end position="2233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="2256"/>
            <end position="2271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="2273"/>
            <end position="2282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="2355"/>
            <end position="2370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="2377"/>
            <end position="2393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG97870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2671" mass="312991" checksum="C1B1E028BB49267F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ86</accession>
    <name>A0A1J1GZ86_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AP-5 complex subunit zeta-1 ARM repeats domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00354900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529136.1">
        <property type="nucleotide sequence ID" value="XM_028672600.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ86"/>
    <dbReference type="GeneID" id="39732079"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00354900"/>
    <dbReference type="OrthoDB" id="371232at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044599">
        <property type="term" value="C:AP-5 adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028222">
        <property type="entry name" value="AP5Z1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055450">
        <property type="entry name" value="AP5Z1_ARM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46488">
        <property type="entry name" value="AP-5 COMPLEX SUBUNIT ZETA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46488:SF1">
        <property type="entry name" value="AP-5 COMPLEX SUBUNIT ZETA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14764">
        <property type="entry name" value="SPG48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP-5 complex subunit zeta-1 ARM repeats" evidence="1">
        <location>
            <begin position="375"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="781" mass="94062" checksum="A60154D015217498" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZA3</accession>
    <name>A0A1J1GZA3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00535400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530577.1">
        <property type="nucleotide sequence ID" value="XM_028674201.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZA3"/>
    <dbReference type="GeneID" id="39733887"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00535400"/>
    <dbReference type="OrthoDB" id="371569at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="512"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="551"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="238"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="521"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="562"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="686" mass="80768" checksum="D5D4F6DD621F2EAC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZG3</accession>
    <name>A0A1J1GZG3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">3-oxo-5-alpha-steroid 4-dehydrogenase, putative</fullName>
            <ecNumber evidence="12">1.3.99.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00363500</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the steroid 5-alpha reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.99.5" evidence="12"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529216.1">
        <property type="nucleotide sequence ID" value="XM_028672689.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZG3"/>
    <dbReference type="GeneID" id="39732165"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00363500"/>
    <dbReference type="OMA" id="ATMPIFN"/>
    <dbReference type="OrthoDB" id="540503at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003865">
        <property type="term" value="F:3-oxo-5-alpha-steroid 4-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01801">
        <property type="entry name" value="Ubl_TECR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000244">
        <property type="entry name" value="3-oxo-5-alpha-steroid 4-dehydrogenase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001104">
        <property type="entry name" value="3-oxo-5_a-steroid_4-DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039357">
        <property type="entry name" value="SRD5A/TECR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10556">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10556:SF28">
        <property type="entry name" value="VERY-LONG-CHAIN ENOYL-COA REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02544">
        <property type="entry name" value="Steroid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50244">
        <property type="entry name" value="S5A_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="7 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="11">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG96411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="296" mass="35271" checksum="C34077A131C6B96D" modified="2017-02-15" version="1">MKVILKKRNGKFIDCFDLSPSTTVEEFKEIFYKKYHYYPERQKWNLDSAAGKTLKSGTFEENGIKDSDILIFKDLGVQISWRLVYVIEYLGPILIFPFFYFCDKYIYSYSNKNKNIIQILSLWFLLFHFIKREFESLFVHRFSNATMPIIRVPINCGHYWVLCGVNIGYYLFHPLYKPHDIVSKPFLVYSLFFVLLILEFLNLKCHLILRNLRPRGTKNRGIPHGYGFKYISCANYFYEVLIWAIFSIITNTLTGYIFTIVATTQMAIWAIKKHKNYKREFPNYPKSRKAIFPFIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZG6</accession>
    <name>A0A1J1GZG6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00426900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529493.1">
        <property type="nucleotide sequence ID" value="XM_028672996.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZG6"/>
    <dbReference type="GeneID" id="39732801"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00426900"/>
    <dbReference type="OMA" id="HIMIGIN"/>
    <dbReference type="OrthoDB" id="378572at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="408"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="623"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="680"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="747"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="858"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="411"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="428"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="998" mass="117793" checksum="328E4B1DD7963044" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZJ7</accession>
    <name>A0A1J1GZJ7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PUB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00522500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530450.1">
        <property type="nucleotide sequence ID" value="XM_028674059.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZJ7"/>
    <dbReference type="GeneID" id="39733758"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00522500"/>
    <dbReference type="OMA" id="VDMIWKF"/>
    <dbReference type="OrthoDB" id="387623at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09212">
        <property type="entry name" value="PUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036339">
        <property type="entry name" value="PUB-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018997">
        <property type="entry name" value="PUB_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09409">
        <property type="entry name" value="PUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00580">
        <property type="entry name" value="PUG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143503">
        <property type="entry name" value="PUG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PUB" evidence="2">
        <location>
            <begin position="308"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="449"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="568" mass="67456" checksum="F35343BF20380475" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZV5</accession>
    <name>A0A1J1GZV5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00041700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG97988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530785.1">
        <property type="nucleotide sequence ID" value="XM_028674432.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZV5"/>
    <dbReference type="GeneID" id="39728942"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00041700"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="177" mass="21559" checksum="D45F6E9BF01103DA" modified="2017-02-15" version="1">MKTFTLYFKITTFLLLIWMYQCFYNCDSYKTLIDKNKLQTENELKYERVLTEGNIPGKKQTYAEGCLKESPLDNKKNKWENPDLYKDPYNYWYKVIIPKLWERFDKETSGISPNTKNREWNVEWPKISNEKANDLYFVKLRRYIPYEEKKKIIDSIMEELDSKFETFLCECKIRNGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H023</accession>
    <name>A0A1J1H023_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00420000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNA polymerase II subunit 5-mediating protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529424.1">
        <property type="nucleotide sequence ID" value="XM_028672919.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H023"/>
    <dbReference type="GeneID" id="39732732"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00420000"/>
    <dbReference type="OMA" id="KFYQDKY"/>
    <dbReference type="OrthoDB" id="21413at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019212">
        <property type="term" value="F:phosphatase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23159">
        <property type="entry name" value="Prefoldin_URI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004127">
        <property type="entry name" value="Prefoldin_subunit_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052255">
        <property type="entry name" value="RNA_pol_II_subunit5-mediator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15111">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT 5-MEDIATING PROTEIN NNX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15111:SF0">
        <property type="entry name" value="UNCONVENTIONAL PREFOLDIN RPB5 INTERACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02996">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="279" mass="32893" checksum="447C8E09C85B49C5" modified="2017-02-15" version="1">MVEDKIEKDKIEGATQRLVSKLTNERLKEEILKKTINEYKQTIEVVSKLTKKLNHKVIIPFSRIAFYEGQIKYTNNIYQNIGCNTYCERTAEKACDYLKKKLDFYEKKYKIITDSINRLTKEIELALELDQTSKIEKNEDNFNAFLRPDGFLEIREEYHSSDEDTNNQKEKNLKNDEEINFEKDSINETKSEKNIVDDKDIDNENVMVQYENIKRYNNEEISNEKINSKKEKLGLSKEKMNLNKANKNISNKSLNINERGFLNIEENYNSSSSNNSYVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H058</accession>
    <name>A0A1J1H058_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fam-h protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00450300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000077">
        <property type="protein sequence ID" value="CRG96922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529725.1">
        <property type="nucleotide sequence ID" value="XM_028673253.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H058"/>
    <dbReference type="GeneID" id="39733036"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00450300"/>
    <dbReference type="OrthoDB" id="10615400at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022139">
        <property type="entry name" value="Fam-L/Fam-M-like_plasmodium"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12420">
        <property type="entry name" value="DUF3671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="106"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="191" mass="22881" checksum="ADEDA7D634E16FB0" modified="2017-02-15" version="1">MRDYINSNIILNSRCNSHTEENFVIEDISTLKKYRTRGKINKLFFFIKISLFTLLIWILLYCENYNYRSRNDKYNLKNKLYLGSKRSLAEGMEVIETTNEELKVSSSNIQTNLEENNTKVEKLELKEKEKDKKEIIKIEDENENVVEKKKESNKKENSFHLMNKYKKTLRIFYVTSIILLPLMLMTLSIWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H073</accession>
    <name>A0A1J1H073_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Multidrug resistance-associated protein 1, putative</fullName>
            <ecNumber evidence="12">3.6.3.44</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">MRP1</name>
        <name evidence="12" type="ORF">PGAL8A_00065500</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.44" evidence="12"/>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028531013.1">
        <property type="nucleotide sequence ID" value="XM_028674685.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729180"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00065500"/>
    <dbReference type="OMA" id="NCITEEL"/>
    <dbReference type="OrthoDB" id="4865934at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000067">
        <property type="entry name" value="Multidrug resistance protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF456">
        <property type="entry name" value="MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN LETHAL(2)03659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="124"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="169"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="310"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="342"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="425"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1074"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1131"/>
            <end position="1154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1160"/>
            <end position="1181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1207"/>
            <end position="1226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1232"/>
            <end position="1250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1318"/>
            <end position="1342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1354"/>
            <end position="1376"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="629"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="1105"/>
            <end position="1328"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="1451"/>
            <end position="1729"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG98216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1730" mass="206234" checksum="271D28EEDB4A3DAC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0C9</accession>
    <name>A0A1J1H0C9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptide chain release factor, putative</fullName>
            <ecNumber evidence="4">3.1.1.29</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00045000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530816.1">
        <property type="nucleotide sequence ID" value="XM_028674467.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0C9"/>
    <dbReference type="GeneID" id="39728975"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00045000"/>
    <dbReference type="OMA" id="HRMVRNS"/>
    <dbReference type="OrthoDB" id="2019491at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:peptidyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003747">
        <property type="term" value="F:translation release factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005139">
        <property type="entry name" value="PCRF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43116:SF3">
        <property type="entry name" value="CLASS I PEPTIDE CHAIN RELEASE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43116">
        <property type="entry name" value="PEPTIDE CHAIN RELEASE FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03462">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00937">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="Release factor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00745">
        <property type="entry name" value="RF_PROK_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prokaryotic-type class I peptide chain release factors" evidence="3">
        <location>
            <begin position="222"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="182"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="194"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG98019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="342" mass="39822" checksum="B2CF25D6DF739041" modified="2017-02-15" version="1">MNFILILIYIFFSIMSIKCKNIALLRSYFFLSKNVKQINKKYLSSYIKKDVENYSKYFKNSCSLILSSGTGGTEACDFCNMLYNMYMKYLSKIKNKKNIKYEVIDISKNEVGLKKVEIKIEGEYSFYNFVSEKGIHRLVRYSPFNAQNKRMTSFVKVDVIPTLNYNDVNIINFLNNAEKTSSKNNKTLEKEKNNNNNNNNNNNNKMNEITINKSDLVIQTMRSGGKGGQNVNKVETAVRILHKPTNISVKVSNERSQILNKRIALKSIYEKLLYLQMEALKNKKYELANKSLTHFGEQIRNYILYGNKMIKDTRTNVYSCDIDKVLLQGEIDLFIDAYQKYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0D3</accession>
    <name>A0A1J1H0D3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">A-kinase anchor protein 7-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00034300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530706.1">
        <property type="nucleotide sequence ID" value="XM_028674344.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0D3"/>
    <dbReference type="GeneID" id="39728867"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00034300"/>
    <dbReference type="OMA" id="TIMKNSY"/>
    <dbReference type="OrthoDB" id="277832at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034237">
        <property type="term" value="F:protein kinase A regulatory subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010738">
        <property type="term" value="P:regulation of protein kinase A signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1140.10">
        <property type="entry name" value="Cyclic phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019510">
        <property type="entry name" value="AKAP7-like_phosphoesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052641">
        <property type="entry name" value="AKAP7_isoform_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009097">
        <property type="entry name" value="Cyclic_Pdiesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15934:SF2">
        <property type="entry name" value="A-KINASE ANCHOR PROTEIN 7-LIKE PHOSPHOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15934">
        <property type="entry name" value="RNA 2',3'-CYCLIC PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10469">
        <property type="entry name" value="AKAP7_NLS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55144">
        <property type="entry name" value="LigT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="A-kinase anchor protein 7-like phosphoesterase" evidence="2">
        <location>
            <begin position="41"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="281" mass="33759" checksum="476EB08801161527" modified="2017-02-15" version="1">MNIKKSICKYLNFYYIFIKSDHNNKKFHFIRENTKMTTIKPNYFICIPLNNEVICNELVKIQNHIVMKYDKLKECSIEKNKFHISLLILYIKKSQIELSKEAFHEAMDEIKKIEHEKILFDKLDTFRNDVLYLSLKESSNDYIINMINVLKKSFEKRDIKIIYNKTKNKNNEKQKKNDNKNEIKNNLDKSDINKDNPIKNNINKNSNDTEKITPHLTIMKNSYMKKIYVNRKPQIFADYYSDFNLTNLLKEHFVANKIQFLEMNIDSFTSYYKILSECNLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0F9</accession>
    <name>A0A1J1H0F9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Heat shock protein 90, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">HSP90</name>
        <name evidence="10" type="ORF">PGAL8A_00048600</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the heat shock protein 90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530848.1">
        <property type="nucleotide sequence ID" value="XM_028674502.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0F9"/>
    <dbReference type="GeneID" id="39729011"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00048600"/>
    <dbReference type="OMA" id="MRRMKEM"/>
    <dbReference type="OrthoDB" id="28737at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16927">
        <property type="entry name" value="HATPase_Hsp90-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.790:FF:000001">
        <property type="entry name" value="Heat shock protein 90 alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.80:FF:000001">
        <property type="entry name" value="Heat shock protein 90 alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11260:FF:000001">
        <property type="entry name" value="Heat shock protein 90 alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000001">
        <property type="entry name" value="Heat shock protein HSP 90-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.790">
        <property type="entry name" value="Heat shock protein 90, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00505">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019805">
        <property type="entry name" value="Heat_shock_protein_90_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037196">
        <property type="entry name" value="HSP90_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001404">
        <property type="entry name" value="Hsp90_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020575">
        <property type="entry name" value="Hsp90_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003555">
        <property type="entry name" value="PRK05218.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11528">
        <property type="entry name" value="HEAT SHOCK PROTEIN 90 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00183">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002583">
        <property type="entry name" value="Hsp90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00775">
        <property type="entry name" value="HEATSHOCK90"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110942">
        <property type="entry name" value="HSP90 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00298">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Histidine kinase/HSP90-like ATPase" evidence="9">
        <location>
            <begin position="26"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="216"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="710"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="226"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="99"/>
            <end position="100"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="119"/>
            <end position="124"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="405"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR002583-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG98051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="731" mass="84709" checksum="C5B96ACCD4AF2DCD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0I3</accession>
    <name>A0A1J1H0I3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Cytochrome c oxidase subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">COX3</name>
        <name evidence="11" type="ORF">PGAL8A_MIT00100</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <geneLocation type="mitochondrion" evidence="11"/>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the cytochrome c oxidase subunit 3 family.</text>
    </comment>
    <dbReference type="EMBL" id="LN835294">
        <property type="protein sequence ID" value="CRG98257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0I3"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_MIT00100"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Mitochondrion MIT"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00386">
        <property type="entry name" value="Heme_Cu_Oxidase_III_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.80">
        <property type="entry name" value="Cytochrome c oxidase, subunit III, four-helix bundle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024791">
        <property type="entry name" value="Cyt_c/ubiquinol_Oxase_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000298">
        <property type="entry name" value="Cyt_c_oxidase-like_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035973">
        <property type="entry name" value="Cyt_c_oxidase_su3-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013833">
        <property type="entry name" value="Cyt_c_oxidase_su3_a-hlx"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11403:SF7">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11403">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00510">
        <property type="entry name" value="COX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81452">
        <property type="entry name" value="Cytochrome c oxidase subunit III-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50253">
        <property type="entry name" value="COX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="62"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="130"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="Heme-copper oxidase subunit III family profile" evidence="10">
        <location>
            <begin position="1"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG98257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="206" mass="23704" checksum="3C5A66AFB22074BC" modified="2017-02-15" version="1">MIFIYSIRESFYSTFSSLASGMLSLIISEALLFVTYFWGILHFSLSPYPLSNEGIILTSSRMLILTITFILASASCMTACLQFLIEKGMSFEISSIVCIIYLIGECFASLQTTEYLHLEYCINDAILGTLFYCVTGLHFSHVIVGLILLLTYFIRIVEVYDTNSEWSYSLFGISYIVLPHSDQITLLYWHFVEIIWLFIEFLFYSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0X0</accession>
    <name>A0A1J1H0X0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Regulator of chromosome condensation, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00053600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530898.1">
        <property type="nucleotide sequence ID" value="XM_028674558.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0X0"/>
    <dbReference type="GeneID" id="39729061"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00053600"/>
    <dbReference type="OMA" id="MYFQCGR"/>
    <dbReference type="OrthoDB" id="8068875at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051553">
        <property type="entry name" value="Ran_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982:SF4">
        <property type="entry name" value="PHR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13540">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG98101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="569" mass="66885" checksum="53C746F4FCCC5586" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1J9</accession>
    <name>A0A1J1H1J9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioredoxin-like protein 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">TrxL1</name>
        <name evidence="2" type="ORF">PGAL8A_00476800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529992.1">
        <property type="nucleotide sequence ID" value="XM_028673551.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1J9"/>
    <dbReference type="GeneID" id="39733301"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00476800"/>
    <dbReference type="OMA" id="CYLGENN"/>
    <dbReference type="OrthoDB" id="189920at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004791">
        <property type="term" value="F:thioredoxin-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031397">
        <property type="term" value="P:negative regulation of protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030178">
        <property type="term" value="P:negative regulation of Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46472">
        <property type="entry name" value="NUCLEOREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46472:SF1">
        <property type="entry name" value="NUCLEOREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13905">
        <property type="entry name" value="Thioredoxin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin-like fold" evidence="1">
        <location>
            <begin position="84"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="218" mass="24995" checksum="9974EFA5C0624446" modified="2017-02-15" version="1">MPRIYKPKSNVTYSKGCYLGENNTGLGGYKITSGAHHLPPCGYAVLEDKKIEMAYGGILQLNDDILKRDYNGFFKPISKDELRNKSVAFYFASYENAKCRSFTPFLTQFYKSINSSTPKEKIEIILVSLDKDEEKFNEHIKHMPWAVVAYNSDLRKHLIKRYQVREDPESLPSGSVPITGLPKLVVVGENGEKLHWLSCDNHSQTILREWDFHSSKWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1M7</accession>
    <name>A0A1J1H1M7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mitogen-activated protein kinase phosphatase 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00501600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530244.1">
        <property type="nucleotide sequence ID" value="XM_028673830.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1M7"/>
    <dbReference type="GeneID" id="39733549"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00501600"/>
    <dbReference type="OMA" id="NGLMNDQ"/>
    <dbReference type="OrthoDB" id="26523at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00158">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="47"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="688" mass="82715" checksum="6D9D88DAF76B814C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1X8</accession>
    <name>A0A1J1H1X8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">General transcription factor IIH subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">P44</name>
        <name evidence="14" type="ORF">PGAL8A_00511200</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the GTF2H2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530340.1">
        <property type="nucleotide sequence ID" value="XM_028673937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1X8"/>
    <dbReference type="GeneID" id="39733645"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00511200"/>
    <dbReference type="OMA" id="ENTICAC"/>
    <dbReference type="OrthoDB" id="284275at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000439">
        <property type="term" value="C:transcription factor TFIIH core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01453">
        <property type="entry name" value="vWA_transcription_factor_IIH_type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007198">
        <property type="entry name" value="Ssl1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004595">
        <property type="entry name" value="TFIIH_C1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012170">
        <property type="entry name" value="TFIIH_SSL1/p44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00622">
        <property type="entry name" value="ssl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12695">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12695:SF2">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07975">
        <property type="entry name" value="C1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04056">
        <property type="entry name" value="Ssl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015919">
        <property type="entry name" value="TFIIH_SSL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01047">
        <property type="entry name" value="C1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 11" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6 11" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="VWFA" evidence="13">
        <location>
            <begin position="83"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="12">
        <location>
            <begin position="302"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR015919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR015919-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG97539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="399" mass="45927" checksum="A19F91405CCE70CC" modified="2017-02-15" version="1">MQNPQNIENKVFEDVVRDFDENEVFEEITGKFTWEQDVERSWNLLVENNGVLQHVSQEKFENKNKQKYKKNQICSLRKGIFRHIIILFDLSSSMKERDFKPDRINVVLECVETFLKNFFFKNPVGHIGIVALKNSSAKLIQPLTSSIDDILNSLLKERSLGLQGSPSLQEGLEIAHDLLIDMPLYGTKEILIMYGSIRTCDKKNILKILELLIKSNIYVNCISIAPEMHILKHICEKTNGIYKICTDKNSLINEINNCAETPLWMNGMEPQLIHICFPIKKKINTQIMCSCHNNLNTDTYICNFCNSYTCKIPSKCKVCGIHLISMHDLSHITNNLQGSPLFTEITNENKQYNLCVSCNQQLDDKVSQCTKCKNIFCIDCDVFIHEDLNQCPFCLINDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2S1</accession>
    <name>A0A1J1H2S1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">S15 sporozoite-expressed protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00521400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530439.1">
        <property type="nucleotide sequence ID" value="XM_028674047.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2S1"/>
    <dbReference type="GeneID" id="39733747"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00521400"/>
    <dbReference type="OrthoDB" id="345191at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="393" mass="44547" checksum="FB1C8D5A2A3205B3" modified="2017-02-15" version="1">MTNVIECTFKAPPPSAKIPENAVIWNEFQYSDEKGWYSLSNHEELSLRPTVFDDKRIKFLPQLQKVPSEFELVLCGKYDAKAWGKDDCNVVIEGEKDVHISLPGLTEKINYNHPVRFPTFLKNWKIIVNLINENVTMIRINTETAVIISINEKKNITVKSIDFNNGFLCVNPHTDLAIAYGDFALSELKKCEKVPPIVHEGGEWGFFVHLFKWGHIIVPKELEMKLPSPGLKLIGKKVDTVAIVSIPPNIHVHVKVDGPKCIKRLEYGKDFNITAIKSSESDVDIYLLFHSQLLKYEFSFDTRLNKPEKGRSNHYAKLKCTSKNKEVSSFTFQQASNLKILLASNCPSDNLGHLLSNQTIAIFNGETGEYLSHPQGLQLTSVFSKLSYPIEKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3H5</accession>
    <name>A0A1J1H3H5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Prefoldin subunit, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00033300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prefoldin subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530695.1">
        <property type="nucleotide sequence ID" value="XM_028674331.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3H5"/>
    <dbReference type="GeneID" id="39728856"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00033300"/>
    <dbReference type="OMA" id="KCYDTIT"/>
    <dbReference type="OrthoDB" id="248120at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051131">
        <property type="term" value="P:chaperone-mediated protein complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002777">
        <property type="entry name" value="PFD_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21431">
        <property type="entry name" value="PREFOLDIN SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21431:SF0">
        <property type="entry name" value="PREFOLDIN SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01920">
        <property type="entry name" value="Prefoldin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="13"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="119" mass="13905" checksum="AC0257CF26518C22" modified="2017-02-15" version="1">MSQEKITKIIKEINTLKTSCEKLNVQLEELITQKVENEMLLEDVKKLEDDAILHKLVGLILVKEEKSKCYDTITRRIHYISGEIESRKKVISNSEEKLKKLFSDLEMYTNQRKIAIPQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3W5</accession>
    <name>A0A1J1H3W5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Hsp70 nucleotide exchange factor FES1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00061200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530972.1">
        <property type="nucleotide sequence ID" value="XM_028674639.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3W5"/>
    <dbReference type="GeneID" id="39729137"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00061200"/>
    <dbReference type="OMA" id="RWSMEYH"/>
    <dbReference type="OrthoDB" id="10250458at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050693">
        <property type="entry name" value="Hsp70_NEF-Inhibitors"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19316:SF18">
        <property type="entry name" value="HSP70-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19316">
        <property type="entry name" value="PROTEIN FOLDING REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG98175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="326" mass="37241" checksum="28B795CC63891BE5" modified="2017-02-15" version="1">MVNINWPGLLKWSTKYADGTIDTNKRLSKEDIEFLQGAIKEALSQVEDPYEAINEAVLNFENKDEGIILASAKIVERLVDEYPEVARNLDKIKAIDPLLKLLDHSNNHILESVLQILSLALSNNPDLQESVFKKNALKTLLIKLQESQKTLIDKKLITAISALIRHHDEAENKFIDYGGVGFLVYGMQTNIYKYQEKSALLLKHLVHQNKITFEIFIKNEIMKGLICLANNKNIDETGIQYGETTAELFLAIIQNHRHKLAKSGNLHNLKKLIEDRLIYLRVIQNSTSYDVSHEMELFNECLKLTNWPGMKLPKENDENNYSIADG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL13</accession>
    <name>A0A1J1GL13_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cytosolic preribosomal GTP-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00071600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525834.1">
        <property type="nucleotide sequence ID" value="XM_028674756.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL13"/>
    <dbReference type="GeneID" id="39729241"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00071600"/>
    <dbReference type="OMA" id="TAICREY"/>
    <dbReference type="OrthoDB" id="603at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01896">
        <property type="entry name" value="DRG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17230">
        <property type="entry name" value="TGS_DRG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000003">
        <property type="entry name" value="Developmentally-regulated GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000740">
        <property type="entry name" value="Putative GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1070">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045001">
        <property type="entry name" value="DRG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031662">
        <property type="entry name" value="GTP-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006074">
        <property type="entry name" value="GTP1-OBG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43127">
        <property type="entry name" value="DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16897">
        <property type="entry name" value="MMR_HSR1_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="TGS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00905">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="3">
        <location>
            <begin position="63"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="4">
        <location>
            <begin position="288"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="365" mass="40656" checksum="7D9D2661ACEE286B" modified="2017-02-15" version="1">MSILQKIADIEAEMAKTQKNKATNYHLGLLKAKLSKLKAQLIEGGTKGGGDGEGFDVSKTGDARIGLVGFPSVGKSTLLNKLTGTFSEVASYEFTTLTCVPGIFKYKGAKMQLLDLPGIIEGAKDGKGRGKQVIAVAKSCSLILIVLDVLKPLTYKKIIEKELEGFGIRLNKKPPNIIFQKKDKGGINITHTVPLNNLDEDIIKSICHEYRIMNANISIRCEATVDDIIDVIEGNRLYVPCIYVLNKVDQITMEELDLITQLPHNVPISAHLEWNLDGLLEAIWNYLDLVRIYTKPKGQIPDYDSPVILKKEKSKVENFCKKIHRSLVQQLKYALVWGKSVKHNPQKVGKDHELNDEDVVQLVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLB0</accession>
    <name>A0A1J1GLB0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Secreted ookinete protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PSOP1</name>
        <name evidence="2" type="ORF">PGAL8A_00084900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525967.1">
        <property type="nucleotide sequence ID" value="XM_028670988.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLB0"/>
    <dbReference type="GeneID" id="39729373"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00084900"/>
    <dbReference type="OrthoDB" id="374222at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012046037" evidence="1">
        <location>
            <begin position="17"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="463" mass="52522" checksum="F6E7604E37A9C88D" modified="2017-02-15" version="1">MNKLLIISFFLYTIAAFKTNKKERDEKISKVLEKQIAKRNPSGSKPFNLRENIDYKRKFNYELYISSDGELQQQRFGVNETRQIIKKNVESFRYLVNDMEILFGVYKFNSRDTEKVLRETLKPESVCFMIVGLIINVLNKIDIDDASLYGLQIKGERNGNNVNSTLGISAIFSNITIPLGNFYFPEVKRVPYQVPFLVGYYNSRSGIKHKSFSHICSLPKFLIDVIHTSKDGLKVNFNGNDIDLKELFPATLAYALENSNSLPNLKDDLQKDERTKLLDILRRDASDVPYRRMKDSGIEGEGIEKPADRILATTSFSNARGKVRDFLASSGKSNMDTDSIALYFLSLSQNIYPRTKESESGRITHVKVTNVQKNASGYLSSFKLDLGLENSRVISIVGTVNGKNIYVPKETISSKTITYNVPFSYGLSLNELGLSYGFSGLFFPFNKILPYNLNNLASFVKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLD5</accession>
    <name>A0A1J1GLD5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RanBP2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00085200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525970.1">
        <property type="nucleotide sequence ID" value="XM_028671021.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLD5"/>
    <dbReference type="GeneID" id="39729376"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00085200"/>
    <dbReference type="OMA" id="NDYNDHT"/>
    <dbReference type="OrthoDB" id="387563at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="173" mass="20599" checksum="B537BDC10AAF5656" modified="2017-02-15" version="1">MKKKCDKNNILIKSHKSKIKHYDKKKSKEKYKKHDKDASSQIYKGTKSNKKISKNYPTNLTDYNKNTGKKNSEISYNSYDYFDKNASDNGLSSNYINEQKLKYEKEVFEKAYGLSLDDDICYDNFLFKKDNGNLDNKNNKKEDSKKYYECFSCKTKNYYSNIQCYKCKKLRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLR9</accession>
    <name>A0A1J1GLR9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00102700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526143.1">
        <property type="nucleotide sequence ID" value="XM_028672943.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLR9"/>
    <dbReference type="GeneID" id="39729552"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00102700"/>
    <dbReference type="OMA" id="NSFHTNN"/>
    <dbReference type="OrthoDB" id="373019at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="305" mass="38008" checksum="A1DDFB92C301CEFB" modified="2017-02-15" version="1">MKYIIILNLFLLYLYNGRKNYFEKIFSFPLILENEEITNIKYKILVYKKKGYSRILYGFFRKHRKKKGSSSRKKKRLENRKKKKQRRERKKEEKKRRKEERKRRKEERKRRKEKKKEEKKKKKKKKKEKKKKKKKKRKKKKKKKKKKKKKKKKKKKKKKRRKKEKREREEEERKKLNIQESRTENEDGNDENEEENDITNERRKYNNGDISQNRSMSQNEANYQHENLYTRDEPMNSFHTNNRRNIEAESNSFTNKNERNLNYSNNGYDNTVDQNENIVINFNKLEHESKGEILRKIKHAVEMLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM01</accession>
    <name>A0A1J1GM01_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">AAA family ATPase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00108500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526202.1">
        <property type="nucleotide sequence ID" value="XM_028673599.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM01"/>
    <dbReference type="GeneID" id="39729611"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00108500"/>
    <dbReference type="OrthoDB" id="377311at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19481">
        <property type="entry name" value="RecA-like_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="899"/>
            <end position="1044"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1134" mass="136663" checksum="4BD6138352C8D0A0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GME5</accession>
    <name>A0A1J1GME5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ARID domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00132100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526438.1">
        <property type="nucleotide sequence ID" value="XM_028674848.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729846"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00132100"/>
    <dbReference type="OMA" id="NHGNYPN"/>
    <dbReference type="OrthoDB" id="338531at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048018">
        <property type="term" value="F:receptor ligand activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16100">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.60">
        <property type="entry name" value="ARID DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001606">
        <property type="entry name" value="ARID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036431">
        <property type="entry name" value="ARID_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37458">
        <property type="entry name" value="THISBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37458:SF1">
        <property type="entry name" value="THISBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01388">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01014">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00501">
        <property type="entry name" value="BRIGHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46774">
        <property type="entry name" value="ARID-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51011">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1920"/>
            <end position="1941"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1964"/>
            <end position="1983"/>
        </location>
    </feature>
    <feature type="domain" description="ARID" evidence="3">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1026"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1146"/>
            <end position="1198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1552"/>
            <end position="1573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1761"/>
            <end position="1780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1146"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1177"/>
            <end position="1190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1552"/>
            <end position="1564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1761"/>
            <end position="1772"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2363" mass="281604" checksum="3520CBF6AFDE86E5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMF9</accession>
    <name>A0A1J1GMF9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Zinc transporter ZIP domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00114300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526259.1">
        <property type="nucleotide sequence ID" value="XM_028674232.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMF9"/>
    <dbReference type="GeneID" id="39729668"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00114300"/>
    <dbReference type="OMA" id="NECYNIF"/>
    <dbReference type="OrthoDB" id="354867at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040">
        <property type="entry name" value="ZINC/IRON TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040:SF140">
        <property type="entry name" value="ZRT (ZRT), IRT- (IRT-) LIKE PROTEIN TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="339"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="376"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="422"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="211"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="444" mass="51453" checksum="B38D0F963AE2F95F" modified="2017-02-15" version="1">MIPYIDKIFAFFSIFFVTIFGAVVPLCIESYSECKLFNLVLGYSGGILLGGGLVHLLPEAREDLNKVKKQQNLHFNYPLCEMFAVLGIFLIIIVEQISDYLIQKRKNRHTEKPNEDNCCNECYNIFFYANKFDYINILNIIRNNKIEDNQMYFINLKNINSSKKDQNVIEKICTNKSAKLGNMNIRYMEKKNICKKIKVQDSFEINSKYKNVSLNRNKNMLISKLNEKKKQNDEKQEVTRDLQSCCEEDMEDSNIYFIQTFSDDIIEEYESDDSIQYNFNKAPIILLLAFSFHSIIEGITLGSVKNSYVTNLSIISHKAFASFSIGINLINKHMKKKKYILFMFLFSLMTPLGILLGLVTNIFASTSSTVIQFLPSILASIGSGTFVYISLFEIIGPLLYTYKIHNHCMHTQKNFAYYKIQYKIQIILLIIIGALSMFILTWYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMK9</accession>
    <name>A0A1J1GMK9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00127800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526393.1">
        <property type="nucleotide sequence ID" value="XM_028674798.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMK9"/>
    <dbReference type="GeneID" id="39729803"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00127800"/>
    <dbReference type="OrthoDB" id="6252103at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034511">
        <property type="term" value="F:U3 snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039241">
        <property type="entry name" value="Rrp9-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19865">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19865:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="390"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="414"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="56"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="98"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="15"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="595" mass="68631" checksum="1127EDE1F7D30BEE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMQ6</accession>
    <name>A0A1J1GMQ6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00132400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526441.1">
        <property type="nucleotide sequence ID" value="XM_028674851.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMQ6"/>
    <dbReference type="GeneID" id="39729849"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00132400"/>
    <dbReference type="OMA" id="FMECAQQ"/>
    <dbReference type="OrthoDB" id="299625at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40515">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40515:SF1">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="93"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="169"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="364" mass="44201" checksum="9F2C7ECFC57232F5" modified="2017-02-15" version="1">MIIEEKEKKNITNDENEITSSINLKNEISLYNNIEEFKESNDNIQKCFESLNNTIENMNVHVNNILKDNEEKYILAFNTYMYDVQKEIRILKKILKEEKIKELKDEKMKKLQKELKWYINECLRLDNISQYLKKEAEKWKRNSSLMKSHMLFLEKKLTKTFDKVIEKKNVKIEEEKKLENENIENKKDIFSEKKNLEQIEKEDENKNENKLKDKRKKDNLNEEMNLKITNLEKKLKKQININSNLQEKLTKYYIEKSKYEKLFIDCVKQIKKDIENKTMINEKEKYIEENFSSLIDESELSYFTKEDKKKLLITFFSSNDLIQFIRKKIFSQEKKMPLDIYKKNSYTNPRMNYQKKSDISPFIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN86</accession>
    <name>A0A1J1GN86_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inositol-polyphosphate 5-phosphatase, putative</fullName>
            <ecNumber evidence="3">3.1.3.56</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00160600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.56" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526719.1">
        <property type="nucleotide sequence ID" value="XM_028675160.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN86"/>
    <dbReference type="GeneID" id="39730131"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00160600"/>
    <dbReference type="OrthoDB" id="405996at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004445">
        <property type="term" value="F:inositol-polyphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043812">
        <property type="term" value="F:phosphatidylinositol-4-phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002013">
        <property type="entry name" value="SAC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45662">
        <property type="entry name" value="PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45662:SF2">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-3-PHOSPHATASE SAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02383">
        <property type="entry name" value="Syja_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50275">
        <property type="entry name" value="SAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="659"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="686"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="729"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="domain" description="SAC" evidence="2">
        <location>
            <begin position="208"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="770" mass="91708" checksum="A5FE0ABE58039A64" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP08</accession>
    <name>A0A1J1GP08_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Suppressor of kinetochore protein 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00173500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the SKP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526849.1">
        <property type="nucleotide sequence ID" value="XM_028670059.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP08"/>
    <dbReference type="GeneID" id="39730262"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00173500"/>
    <dbReference type="OMA" id="DKYTASM"/>
    <dbReference type="OrthoDB" id="2342932at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18322">
        <property type="entry name" value="BTB_POZ_SKP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.710.10:FF:000127">
        <property type="entry name" value="Suppressor of kinetochore protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016897">
        <property type="entry name" value="SKP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001232">
        <property type="entry name" value="SKP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036296">
        <property type="entry name" value="SKP1-like_dim_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016072">
        <property type="entry name" value="Skp1_comp_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016073">
        <property type="entry name" value="Skp1_comp_POZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11165">
        <property type="entry name" value="SKP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01466">
        <property type="entry name" value="Skp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03931">
        <property type="entry name" value="Skp1_POZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028729">
        <property type="entry name" value="E3_ubiquit_lig_SCF_Skp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00512">
        <property type="entry name" value="Skp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81382">
        <property type="entry name" value="Skp1 dimerisation domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="SKP1 component POZ" evidence="5">
        <location>
            <begin position="4"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="SKP1 component dimerisation" evidence="4">
        <location>
            <begin position="112"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR028729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG94028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="162" mass="18928" checksum="479D97CC8E76A235" modified="2017-02-15" version="1">MKNDKIKLVSFEGDEFIVDKYTASMSTVIMNILEVMTEEEDTIPLPNIKTQILKKIIEYMEYHIQNPADEIPKPLSTSNLQDVVSSWDYDFVNTDKETLYELIEASNYLDIKPLLDLTCGKIASMMKDKTTEEIRAEFDIVNDFTREEEKQIREENRWCGDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP09</accession>
    <name>A0A1J1GP09_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BSD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00392700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527044.1">
        <property type="nucleotide sequence ID" value="XM_028670275.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP09"/>
    <dbReference type="GeneID" id="39732457"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00392700"/>
    <dbReference type="OrthoDB" id="360521at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005607">
        <property type="entry name" value="BSD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058878">
        <property type="entry name" value="PH_plasmodium"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26279">
        <property type="entry name" value="PH_37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00751">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50858">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BSD" evidence="1">
        <location>
            <begin position="281"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="648" mass="78229" checksum="89A6A50DA56F51C7" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP81</accession>
    <name>A0A1J1GP81_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00078900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525909.1">
        <property type="nucleotide sequence ID" value="XM_028670344.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP81"/>
    <dbReference type="GeneID" id="39729314"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00078900"/>
    <dbReference type="OrthoDB" id="371817at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="408" mass="48951" checksum="9055F905EFCE4969" modified="2017-02-15" version="1" fragment="single">MKFFPLKSDIINEPESNQKLKKMYTDLLTFSETPDINSEIYDKILNLNSQEYKMQKNKKSSIFSKNGYIGNCFHEYMSDCDITLSKVRDKNIENDKEEKKKEKEKYVEKEKEEEEDEEEEDEQEEEEENEQEEEDEQYEKEEEIYDNEIEEKSYHDKIKNGQYDNYCIGIYEEKGHKDAYECEKEKINIDKKSKVKKEKSINNSCWKDIISKNNTILNKSNNNFKNIDEENVIIDIILDIYKNTMEHKKTHFLCLEEILKKINLILKKQVEICKSNVYQKSERQLLFQNIYELKKQIADKAFNSLANKDFARCYIKNIHSENIKDNIDKNTERNILNFKNLEKINEKSDKYYKDIYEKFKTKSENVNLFLFHLNELEKSIYAFTHFCRNVSSLTYPDGMIGLNSLEQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPB2</accession>
    <name>A0A1J1GPB2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00395700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527074.1">
        <property type="nucleotide sequence ID" value="XM_028670308.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPB2"/>
    <dbReference type="GeneID" id="39732487"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00395700"/>
    <dbReference type="OrthoDB" id="328333at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="133" mass="16364" checksum="F4F7761FF0E6A507" modified="2017-02-15" version="1">MNFDIAFDGNEYTYSGYSKNSLIEDKNYTLDYDKYVHFAFFTCFYISHIKKKQCSDTELLAWYLKKFKHIVINSTKKVRRTYFNLINNLIQDKCVKAIIENNKRYLIHNENFILWAWKRRVLKFDKEQFNRFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPB5</accession>
    <name>A0A1J1GPB5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">mitogen-activated protein kinase kinase</fullName>
            <ecNumber evidence="6">2.7.12.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">PK7</name>
        <name evidence="11" type="ORF">PGAL8A_00404100</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10596"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.12.2" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527158.1">
        <property type="nucleotide sequence ID" value="XM_028670402.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPB5"/>
    <dbReference type="GeneID" id="39732571"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00404100"/>
    <dbReference type="OMA" id="YMENESI"/>
    <dbReference type="OrthoDB" id="68483at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004708">
        <property type="term" value="F:MAP kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004713">
        <property type="term" value="F:protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48013:SF9">
        <property type="entry name" value="DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48013">
        <property type="entry name" value="DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="28"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00051693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG94337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="346" mass="41731" checksum="C31E42365069ACC8" modified="2017-02-15" version="1">MEEILNNYPNVYQLNKYKKENTKFINDYKVIRTLSQGKLNKIILCEKDNKLYVLKKYNKKWLEKKRDFYKNTNNEVILKSKFDDLKTELKILIDINNEYCLSCEKIITDYNKIYVLNEYMENESILKYDEFFFVLDKEESFFIPLAVIKCIIKNILKSFLYLHKKKNICHRDIKPSNILLSKNGKIKLCDYGESQYMTDKKIRGTKGTYEFMPPEFFSKESYYDGEKVDIWSLGICLYALFYRVLPFNSKNSLIQLFNDIGKAEIEYHKDRNYFLFQITKKKCNCSNNFLTSEDINFLKCFLKKNPNERHTSEQALKNNWLNDVNYKYIEDYAEEIYKRKINHSFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPG0</accession>
    <name>A0A1J1GPG0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Zinc finger protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00401300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527130.1">
        <property type="nucleotide sequence ID" value="XM_028670371.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPG0"/>
    <dbReference type="GeneID" id="39732543"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00401300"/>
    <dbReference type="OMA" id="KNFCSCF"/>
    <dbReference type="OrthoDB" id="337581at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04434">
        <property type="entry name" value="SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="2">
        <location>
            <begin position="121"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="189" mass="22431" checksum="A3D316D5D582B5BE" modified="2017-02-15" version="1">MDIRTKTVNSIIFSLKGCKNKNKYILLINELLSLFPLHAEKSLRLCLQWKIKKYTLIKESLFSKDFKFFGNSLRINKKTLKKENKKSFSDTNVVHKEEGLGRNIFNKSKKKKWKKTNIHFFVVNGNNKYIVLKNFCSCFYFKEKVLCSNSDVLCKHILSVLLAKCFNCYSNICLNEDLFYEWYIKKLHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPH8</accession>
    <name>A0A1J1GPH8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00391000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527027.1">
        <property type="nucleotide sequence ID" value="XM_028670257.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPH8"/>
    <dbReference type="GeneID" id="39732440"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00391000"/>
    <dbReference type="OrthoDB" id="329772at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="660"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="141"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="798" mass="96886" checksum="39B270452655D2B8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPI3</accession>
    <name>A0A1J1GPI3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-i protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00180600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527238.1">
        <property type="nucleotide sequence ID" value="XM_028670491.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPI3"/>
    <dbReference type="GeneID" id="39730333"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00180600"/>
    <dbReference type="OMA" id="YEEECKM"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="397"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="444"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="482" mass="58992" checksum="10BF36363989A1B4" modified="2017-02-15" version="1">MDPNLSDAASTDSNDSLSEGDSTAAFAHSQIKDAVVSIPKNPLYDDSNLRSAIQNPSGDIKLDSAKSTNVLHKKSLSFFQLVIIIISILRFARARSPKLKAKHKERVKLQNKWDNRDKKMKGDREKMQKKWDERKQKENREKEELNKKEEERKKKTNNEMKEFNMKWNGEKERVNDSEDKSLQILNSSSESRKNIESLNKPSTSQACNITVKIKENNNMPSDNKEEKLREKSSNKVYSQIELELERKRIEAFYKQMFQIDEKWKRYEEECKMKYEWEKGERKKLEEIRRERKRKHEEKMLKEQEEWNKSMREKKKEWEKRMPKEKEEWERRMPKEEEWGENTVLKEMMDELENRRRKELEELEKRMQKEKEELEKRIQKEKEELKKKFQEEIKEKEEGGNRMLKETKEKEEWEKGMQEENEEWKNIFQKEKEKWEKKMQKEKEEWQREENRKVNEEESKLQSKWRKELDKIRKKESNKIEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPL5</accession>
    <name>A0A1J1GPL5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Zinc finger protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00093500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526053.1">
        <property type="nucleotide sequence ID" value="XM_028671943.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729459"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00093500"/>
    <dbReference type="OMA" id="NYAHNIN"/>
    <dbReference type="OrthoDB" id="757982at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042778">
        <property type="entry name" value="ZCWPW1/ZCWPW2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011124">
        <property type="entry name" value="Znf_CW"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15999">
        <property type="entry name" value="ZINC FINGER CW-TYPE PWWP DOMAIN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15999:SF2">
        <property type="entry name" value="ZINC FINGER CW-TYPE PWWP DOMAIN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07496">
        <property type="entry name" value="zf-CW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51050">
        <property type="entry name" value="ZF_CW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CW-type" evidence="7">
        <location>
            <begin position="90"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="CW-type" evidence="7">
        <location>
            <begin position="642"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="167"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="450"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1193"/>
            <end position="1213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1556"/>
            <end position="1578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1600"/>
            <end position="1623"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="2856"/>
            <end position="2951"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="172"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="450"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="475"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="485"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1201"/>
            <end position="1211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1564"/>
            <end position="1578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3274" mass="392897" checksum="733587D3D75CFDE6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPN1</accession>
    <name>A0A1J1GPN1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Plasmodium RESA N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00186100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000024">
        <property type="protein sequence ID" value="CRG94466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527286.1">
        <property type="nucleotide sequence ID" value="XM_028670545.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPN1"/>
    <dbReference type="GeneID" id="39730388"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00186100"/>
    <dbReference type="OMA" id="ELESIFW"/>
    <dbReference type="OrthoDB" id="10589825at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.180">
        <property type="entry name" value="Plasmodium RESA, N-terminal helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019111">
        <property type="entry name" value="PRESA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044885">
        <property type="entry name" value="PRESA_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36193">
        <property type="entry name" value="PHISTB DOMAIN-CONTAINING RESA-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36193:SF23">
        <property type="entry name" value="PHISTB DOMAIN-CONTAINING RESA-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09687">
        <property type="entry name" value="PRESAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plasmodium RESA N-terminal" evidence="1">
        <location>
            <begin position="108"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="233" mass="26958" checksum="7B2BC0EEC73DF257" modified="2017-02-15" version="1">MINVILPKQSAIDPTIMKCFSVSSLEGENYVFKNKSNRNFMFCKIYVLSFLCLFFFTHHDKCNSQGNVSSEFNFKYSISRKLAASNDGRNANEESFDEFIGRFLDDNEDNENMDENISSEKALSILNDIQSQEEKKLHDNLKTLLDKLNKEAQSYGVPGAAADKMWSTITKETTDAMNKLIQKLHQELSSLVSGGSCTRREFKGFTDNAFFLWGKLRHELESIFWRRFYSLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPV1</accession>
    <name>A0A1J1GPV1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00075600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525872.1">
        <property type="nucleotide sequence ID" value="XM_028675178.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPV1"/>
    <dbReference type="GeneID" id="39729281"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00075600"/>
    <dbReference type="OrthoDB" id="338345at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="513" mass="60178" checksum="84A7831DBD31FFDE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ10</accession>
    <name>A0A1J1GQ10_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00191100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000028">
        <property type="protein sequence ID" value="CRG94514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527330.1">
        <property type="nucleotide sequence ID" value="XM_028670593.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ10"/>
    <dbReference type="GeneID" id="39730436"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00191100"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="130" mass="15369" checksum="C0A037EC4756C5CB" modified="2017-02-15" version="1">MCANSNYNGKLIHLIEQYGLSPPNEERIVYLPNKCLKSDSNLLCTPYMCIKNDFNESYSCEYEEISIVKNIFPSPETFKAISTNHKAIYHESNLRSSSVYAMTLMPFLIIFIFFFCYMYKIFRKKRRKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ13</accession>
    <name>A0A1J1GQ13_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00081800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525936.1">
        <property type="nucleotide sequence ID" value="XM_028670644.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729342"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00081800"/>
    <dbReference type="OMA" id="FENIHND"/>
    <dbReference type="OrthoDB" id="6093641at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="832"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1019"/>
            <end position="1197"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="40"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="832"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="880"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="921"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="935"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1019"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1040"/>
            <end position="1197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1360" mass="159832" checksum="50482E0F3EF8D90A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ63</accession>
    <name>A0A1J1GQ63_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00206600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527484.1">
        <property type="nucleotide sequence ID" value="XM_028670764.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ63"/>
    <dbReference type="GeneID" id="39730593"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00206600"/>
    <dbReference type="OMA" id="EYEPYFG"/>
    <dbReference type="OrthoDB" id="374462at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="252" mass="30259" checksum="CC8709547C9DF237" modified="2017-02-15" version="1">MFIPQRLIVHYHHCSINNIGDIFIDYINVQLFFLKNFFNCSLIQFVEEIHPYSNNGSYPYAFNTLEGNVLHDTEIIDYMKNIYLFDLADYEMYIGLINELNIILIYYLWVDDNIYNNFTKKIYKDRFFYLYYIYLIRKLRKENLEKCQMRGLDNHKLNITRLKTILNILDETIGNSVNSTNRSDICYFHSVCFSVLSIFYSIPSKFNKELQAVLISRPNLIEFVKNINNKYKIWKNEKVFLSGINDVFFKSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ90</accession>
    <name>A0A1J1GQ90_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">S-adenosylmethionine-dependent methyltransferase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00209800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the methyltransferase superfamily. RlmI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527516.1">
        <property type="nucleotide sequence ID" value="XM_028670800.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ90"/>
    <dbReference type="GeneID" id="39730625"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00209800"/>
    <dbReference type="OrthoDB" id="269872at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11572">
        <property type="entry name" value="RlmI_M_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="entry name" value="PUA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.80">
        <property type="entry name" value="RNA methyltransferase domain (HRMD) like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041532">
        <property type="entry name" value="RlmI-like_PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42873">
        <property type="entry name" value="RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42873:SF1">
        <property type="entry name" value="S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17785">
        <property type="entry name" value="PUA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50890">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PUA" evidence="9">
        <location>
            <begin position="48"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG94701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="549" mass="64355" checksum="A1DC123230A0E67A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQD4</accession>
    <name>A0A1J1GQD4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nuclear nucleic acid-binding protein C1D</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00204700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer and homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the C1D family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527466.1">
        <property type="nucleotide sequence ID" value="XM_028670744.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQD4"/>
    <dbReference type="GeneID" id="39730574"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00204700"/>
    <dbReference type="OMA" id="DNPPGCK"/>
    <dbReference type="OrthoDB" id="10261072at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000178">
        <property type="term" value="C:exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011082">
        <property type="entry name" value="Exosome-assoc_fac/DNA_repair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007146">
        <property type="entry name" value="Sas10/Utp3/C1D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15341:SF3">
        <property type="entry name" value="NUCLEAR NUCLEIC ACID-BINDING PROTEIN C1D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15341">
        <property type="entry name" value="SUN-COR STEROID HORMONE RECEPTOR CO-REPRESSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04000">
        <property type="entry name" value="Sas10_Utp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 6" id="KW-0698">rRNA processing</keyword>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="94"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="147" mass="17446" checksum="710BD42E5754495D" modified="2017-02-15" version="1">MDENEKSQSMKCKGDIQYEKEKENFEIVKSLNPSIKEFQNNFRLLSENYSLRDLEKELNPVEYADYNSFLAYSICSLFYAYLKISGDLINNHPIKNELKRVQALMKEIKEKNHEISEERSLTINKEASKRIIDSCVSYNKNLKKRKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQJ4</accession>
    <name>A0A1J1GQJ4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Signal recognition particle 54 kDa protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PGAL8A_00209300</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.4"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="13">The M domain binds the 7SL RNA in presence of SRP19 and binds the signal sequence of presecretory proteins.</text>
    </comment>
    <comment type="domain">
        <text evidence="13">The NG domain, also named G domain, is a special guanosine triphosphatase (GTPase) domain, which binds GTP and forms a guanosine 5'-triphosphate (GTP)-dependent complex with a homologous NG domain in the SRP receptor subunit SRPRA. The two NG domains undergo cooperative rearrangements upon their assembly, which culminate in the reciprocal activation of the GTPase activity of one another. SRP receptor compaction upon binding with cargo-loaded SRP and GTPase rearrangement drive SRP-mediated cotranslational protein translocation into the ER.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the GTP-binding SRP family. SRP54 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527511.1">
        <property type="nucleotide sequence ID" value="XM_028670794.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQJ4"/>
    <dbReference type="GeneID" id="39730620"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00209300"/>
    <dbReference type="OMA" id="GMTGQDA"/>
    <dbReference type="OrthoDB" id="10250817at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030942">
        <property type="term" value="F:endoplasmic reticulum signal peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006616">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane, translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17875">
        <property type="entry name" value="SRP54_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.260.30:FF:000005">
        <property type="entry name" value="Signal recognition particle 54 kDa protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000022">
        <property type="entry name" value="Signal recognition particle 54 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="entry name" value="Signal recognition particle SRP54, nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.30">
        <property type="entry name" value="Signal recognition particle, SRP54 subunit, M-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00306">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036891">
        <property type="entry name" value="Signal_recog_part_SRP54_M_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004125">
        <property type="entry name" value="Signal_recog_particle_SRP54_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036225">
        <property type="entry name" value="SRP/SRP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022941">
        <property type="entry name" value="SRP54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006325">
        <property type="entry name" value="SRP54_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01425">
        <property type="entry name" value="SRP54_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 54K PROTEIN SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564:SF5">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE SUBUNIT SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02978">
        <property type="entry name" value="SRP_SPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47364">
        <property type="entry name" value="Domain of the SRP/SRP receptor G-proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47446">
        <property type="entry name" value="Signal peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 13" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 13" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="8 13" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="10 13" id="KW-0733">Signal recognition particle</keyword>
    <feature type="domain" description="SRP54-type proteins GTP-binding" evidence="14">
        <location>
            <begin position="269"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU364034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG94696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="500" mass="56016" checksum="7C7BD09B05049B30" modified="2017-02-15" version="1">MVLTELGTQITNAFRKLQSATVVDDNVIEECLKEVIRALILSDINISYLKDIKSNIKNNIEKNIDIYGNNKKKLVQKYVVEELINLLEGKKESYVPKKGKRNVILFVGLQGSGKTTTCTKYAHYYQKKGFKTALVCADTFRAGAFDQLKQNAAKVKIPFYGSYTEVDPVKIAKDGVNAFLKDKYDLIIVDSSGRHKQENELFEEMKQVENSIKPEEIIFVIDSHIGQSCHEQAMAFKNSVTIGSIIITKIDGHAKGGGALSAVAATGCPITYIGTGEHVNDFEKFEAKSFVSRLLGLGDISGLVSTIKEVIDIDKQPQLMNRLSKGKFVLRDMYDQFQNVFKMGSLSKVISMIPGFGNNLISKGTEKEGIDKIKKFMVIMDSMTNEELDCVKPLSESRCIRIVKGSGTKMQDIKELLEQFKFLQKMVSKMGKLGLRENNISNLMRNQKQLLSKMNNMMDTNMLKQMGGANNMVNLLKEFSKMEDLGGTMSNMMKQMGLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQL9</accession>
    <name>A0A1J1GQL9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA pseudouridylate synthase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00129000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526405.1">
        <property type="nucleotide sequence ID" value="XM_028674811.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQL9"/>
    <dbReference type="GeneID" id="39729815"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00129000"/>
    <dbReference type="OMA" id="LYQGFHK"/>
    <dbReference type="OrthoDB" id="440619at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050343">
        <property type="entry name" value="RsuA_PseudoU_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47683">
        <property type="entry name" value="PSEUDOURIDINE SYNTHASE FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47683:SF2">
        <property type="entry name" value="RNA-BINDING S4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Pseudouridine synthase RsuA/RluA-like" evidence="2">
        <location>
            <begin position="309"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="499" mass="59510" checksum="E2F20E61661744A8" modified="2017-02-15" version="1">MLVNYIRLKLRRCNNNLNNFKNFYRYISDDIKEEIVTHSYNKKEYEKNIDISEQCKSYIDLKQKIFYDYLSKKTLTFIKKKTIKDSKKNNDDKKKLIENGSLIDYINKEKEICENDENLSVEYLSEYKKLNKILNKNGKIEDEKNKTTISNEKIKKKDGMTLKKIGKEKINKDTKKNIKKSYCEEIKRDDIYVNNNEIKNVKKCETPNEIFLSINNSPNTISNDLINIYIDNSKYFTFYDEQKEIKEMKLNQYCSHYGICSSRFAFKNLKNGILKVNDKIIYENVNVCLHKDKIELTKRGEELLKNKITIIINKPKNYLSLSTDIKSNKKLLVRNLIRNENKYVEEDHKCMSYFIYKNVNIEKVNNLYVCGRLDANSSGLLIYTQNTLSHNYLLNKYKYKIEKEYIITTHNEIKEINLKLLRQNLYIDGKLIYKCHIKYIDGFTLIFKLYQGFHKIIRKICLLSNIKIKSLHRVKIGNIHLNNLPTGKWRFLMPNESFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQQ5</accession>
    <name>A0A1J1GQQ5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WD repeat-containing protein 79</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00226600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527684.1">
        <property type="nucleotide sequence ID" value="XM_028670986.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQQ5"/>
    <dbReference type="GeneID" id="39730793"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00226600"/>
    <dbReference type="OMA" id="PKLLQWD"/>
    <dbReference type="OrthoDB" id="239865at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008290">
        <property type="term" value="C:F-actin capping protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019771">
        <property type="entry name" value="F-actin_capping_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051150">
        <property type="entry name" value="SWT21/TCAB1_mRNA_Telomere"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13211">
        <property type="entry name" value="TELOMERASE CAJAL BODY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13211:SF0">
        <property type="entry name" value="TELOMERASE CAJAL BODY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00231">
        <property type="entry name" value="F_ACTIN_CAPPING_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="526" mass="62445" checksum="4F56C6ACF509A46A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQR8</accession>
    <name>A0A1J1GQR8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Kinesin-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00109100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526208.1">
        <property type="nucleotide sequence ID" value="XM_028673666.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQR8"/>
    <dbReference type="GeneID" id="39729617"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00109100"/>
    <dbReference type="OMA" id="YEHNYEH"/>
    <dbReference type="OrthoDB" id="123929at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005871">
        <property type="term" value="C:kinesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24115">
        <property type="entry name" value="KINESIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24115:SF996">
        <property type="entry name" value="PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0505">Motor protein</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="3">
        <location>
            <begin position="48"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="127"/>
            <end position="134"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="882" mass="103223" checksum="6261C704DF421FAE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQU5</accession>
    <name>A0A1J1GQU5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MSP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00203300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527451.1">
        <property type="nucleotide sequence ID" value="XM_028670727.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730559"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00203300"/>
    <dbReference type="OMA" id="CYRKNKY"/>
    <dbReference type="OrthoDB" id="442692at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:axoneme"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="Hydin-like"/>
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            <end position="2493"/>
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            <end position="4213"/>
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            <end position="3208"/>
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        </location>
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            <end position="5749"/>
        </location>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="CRG94636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="6733" mass="804151" checksum="30C98F98C43A9310" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQW9</accession>
    <name>A0A1J1GQW9_PLAGA</name>
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        <submittedName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00225600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
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            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <feature type="compositionally biased region" description="Low complexity" evidence="1">
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        </source>
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        <source>
            <dbReference type="EMBL" id="CRG94859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2200" mass="259346" checksum="654703967BFC9C05" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
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        </submittedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="7 8">
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                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
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    <comment type="similarity">
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    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
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    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00219100"/>
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        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291:SF32">
        <property type="entry name" value="BAX INHIBITOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00010350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG94794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="244" mass="28153" checksum="F4064B937D49E862" modified="2017-02-15" version="1">MDFLKQIRKRQNDIKLSHIFNFSPLTHEEKNHLIKVYGLLAIGTMVTALSCYFDIYFIKIPRFLASIVSLICSFALAWSCNSHYDLATRSKKRLLYFGGMSVSIGILISDYISYVNYLNPSILPLALFGSLSIFCCFSLAAIFSKNRISLFLSAALCAVCSYVTLISFMNFFIRSKFIDTTLLYIGFFMYMGFVLFDTQITLFDFRRGNKDYIMHSICLYLDLVGLFTHLLRILSQKEEEKKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRC9</accession>
    <name>A0A1J1GRC9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00222500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527643.1">
        <property type="nucleotide sequence ID" value="XM_028670940.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730752"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00222500"/>
    <dbReference type="OMA" id="FFYECID"/>
    <dbReference type="OrthoDB" id="380950at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031431">
        <property type="term" value="C:Dbf4-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043539">
        <property type="term" value="F:protein serine/threonine kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010571">
        <property type="term" value="P:positive regulation of nuclear cell cycle DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901987">
        <property type="term" value="P:regulation of cell cycle phase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051590">
        <property type="entry name" value="Replication_Regulatory_Kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15375">
        <property type="entry name" value="ACTIVATOR OF S-PHASE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15375:SF22">
        <property type="entry name" value="PROTEIN DBF4 HOMOLOG A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1066"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
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            <end position="1397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="3871"/>
            <end position="3894"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
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            <end position="3962"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
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            <end position="4093"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="4099"/>
            <end position="4120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="4413"/>
            <end position="4446"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1954"/>
            <end position="1981"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2320"/>
            <end position="2354"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2468"/>
            <end position="2495"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3474"/>
            <end position="3518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="4416"/>
            <end position="4445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="5505" mass="669292" checksum="7EC5E998D6DE9FBB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRL2</accession>
    <name>A0A1J1GRL2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dynein light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00163700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the dynein light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526749.1">
        <property type="nucleotide sequence ID" value="XM_028675193.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRL2"/>
    <dbReference type="SMR" id="A0A1J1GRL2"/>
    <dbReference type="GeneID" id="39730162"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00163700"/>
    <dbReference type="OMA" id="MIYFQHK"/>
    <dbReference type="OrthoDB" id="370653at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21450">
        <property type="entry name" value="DLC-like_DYNLL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.740.10">
        <property type="entry name" value="Protein Inhibitor Of Neuronal Nitric Oxide Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037177">
        <property type="entry name" value="DLC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001372">
        <property type="entry name" value="Dynein_light_chain_typ-1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11886">
        <property type="entry name" value="DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11886:SF35">
        <property type="entry name" value="DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01221">
        <property type="entry name" value="Dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01375">
        <property type="entry name" value="Dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54648">
        <property type="entry name" value="DLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="1" id="KW-0243">Dynein</keyword>
    <keyword evidence="1" id="KW-0493">Microtubule</keyword>
    <keyword evidence="1" id="KW-0505">Motor protein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU365010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="122" mass="14260" checksum="658A496E78A6836C" modified="2017-02-15" version="1">MMELSDVKKYSSKFEIKGICMNSENCEKISKITLKAIKENKFEKDIASQIKLKCENDEILNKDNINDKNCLDDIDNLKNQNIGSWQCIVGKNFAFSINYQFNCMIYFQHKLTKLTILIYKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRQ6</accession>
    <name>A0A1J1GRQ6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zinc finger protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00255400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527962.1">
        <property type="nucleotide sequence ID" value="XM_028671295.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731082"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00255400"/>
    <dbReference type="OMA" id="YNENCHE"/>
    <dbReference type="OrthoDB" id="264354at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16495">
        <property type="entry name" value="RING_CH-C4HC3_MARCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46210">
        <property type="entry name" value="FHA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46210:SF1">
        <property type="entry name" value="FHA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-CH-type" evidence="6">
        <location>
            <begin position="149"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="5">
        <location>
            <begin position="270"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="363"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="452"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="488"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1457"/>
            <end position="1478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1490"/>
            <end position="1708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="363"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="501"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="522"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="659"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1490"/>
            <end position="1514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1520"/>
            <end position="1538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1552"/>
            <end position="1581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1589"/>
            <end position="1708"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1840" mass="215850" checksum="F83F3D3286296AF8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRW5</accession>
    <name>A0A1J1GRW5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00148400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526600.1">
        <property type="nucleotide sequence ID" value="XM_028675028.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRW5"/>
    <dbReference type="GeneID" id="39730008"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00148400"/>
    <dbReference type="OrthoDB" id="371938at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013334865" evidence="3">
        <location>
            <begin position="21"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="604"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="481"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="550"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="481"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="550"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="562"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="627" mass="73411" checksum="6C2028427AA7BB18" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRZ5</accession>
    <name>A0A1J1GRZ5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Superoxide dismutase [Fe]</fullName>
            <ecNumber evidence="5">1.15.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">FeSOD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PGAL8A_00152000</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the iron/manganese superoxide dismutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526632.1">
        <property type="nucleotide sequence ID" value="XM_028675063.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRZ5"/>
    <dbReference type="GeneID" id="39730044"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00152000"/>
    <dbReference type="OMA" id="KIYQGHD"/>
    <dbReference type="OrthoDB" id="239262at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.990">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="entry name" value="Iron/manganese superoxide dismutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001189">
        <property type="entry name" value="Mn/Fe_SOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019833">
        <property type="entry name" value="Mn/Fe_SOD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019831">
        <property type="entry name" value="Mn/Fe_SOD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42769">
        <property type="entry name" value="SUPEROXIDE DISMUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42769:SF3">
        <property type="entry name" value="SUPEROXIDE DISMUTASE [FE] 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00081">
        <property type="entry name" value="Sod_Fe_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01703">
        <property type="entry name" value="MNSODISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46609">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00088">
        <property type="entry name" value="SOD_MN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013289317" description="Superoxide dismutase [Fe]" evidence="12">
        <location>
            <begin position="27"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Manganese/iron superoxide dismutase N-terminal" evidence="13">
        <location>
            <begin position="72"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Manganese/iron superoxide dismutase C-terminal" evidence="14">
        <location>
            <begin position="160"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00014767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG93811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="265" mass="31356" checksum="488A13B10DF3D1C8" modified="2017-02-15" version="1">MNFNIFIIFMYIVVLMEHKILKGVYGLKHICKLSYINFNGFLHLKSNRCFSKTDESLYDRWGIKPLWNSKPFSLIKLPFNPQSMSPFLSEEAIEYHYSKHHATYVKNLNNLAEQHVEIKNLTLEDIITKYKGSIYNNAAQIFNHNFFWMGLKEEGGGKPYGEIKKKIEESFNSFENFKEIFFKEASGHFGSGWIWLIIKDKKLKIYQGHDADNPIKDDVGNPILTLDIWEHAYYVDYKNSRADYIKEWFNKINWDFANYNLSIVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS20</accession>
    <name>A0A1J1GS20_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">40S ribosomal protein S23, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00006200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528108.1">
        <property type="nucleotide sequence ID" value="XM_028671458.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS20"/>
    <dbReference type="GeneID" id="39728584"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00006200"/>
    <dbReference type="OMA" id="KFRWSQR"/>
    <dbReference type="OrthoDB" id="1713912at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03367">
        <property type="entry name" value="Ribosomal_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000007">
        <property type="entry name" value="40S ribosomal protein S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006032">
        <property type="entry name" value="Ribosomal_uS12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005680">
        <property type="entry name" value="Ribosomal_uS12_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00982">
        <property type="entry name" value="uS12_E_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11652">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S12 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00164">
        <property type="entry name" value="Ribosom_S12_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002133">
        <property type="entry name" value="Ribosomal_S12/S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00055">
        <property type="entry name" value="RIBOSOMAL_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="145" mass="16171" checksum="C93E9666AD74465F" modified="2017-02-15" version="1">MGSGKPRGLRAARKLRIRRRTQKWADKSYKKSHLGTRWKSNPFRGSSHAKGIVVEKVAIEAKQPNSAYRKCVRVQLIKNGKKITAFVPGDGCLNFIDENDEVLVSGFGRSGHSVGDLPGVKFKVVKVARVSLLALFKEKKEKPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS87</accession>
    <name>A0A1J1GS87_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UDP-N-acetylglucosamine diphosphorylase</fullName>
            <ecNumber evidence="3">2.7.7.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00254700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>N-acetyl-alpha-D-glucosamine 1-phosphate + UTP + H(+) = UDP-N-acetyl-alpha-D-glucosamine + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13509"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="EC" id="2.7.7.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; UDP-N-acetyl-alpha-D-glucosamine from N-acetyl-alpha-D-glucosamine 1-phosphate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UDPGP type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.23" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527955.1">
        <property type="nucleotide sequence ID" value="XM_028671287.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS87"/>
    <dbReference type="GeneID" id="39731075"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00254700"/>
    <dbReference type="OMA" id="THCTVPW"/>
    <dbReference type="OrthoDB" id="532420at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003977">
        <property type="term" value="F:UDP-N-acetylglucosamine diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039741">
        <property type="entry name" value="UDP-sugar_pyrophosphorylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002618">
        <property type="entry name" value="UDPGP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11952:SF2">
        <property type="entry name" value="LD24639P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11952">
        <property type="entry name" value="UDP- GLUCOSE PYROPHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01704">
        <property type="entry name" value="UDPGP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="569" mass="66472" checksum="FB70141A442A49F8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSX3</accession>
    <name>A0A1J1GSX3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00279300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528404.1">
        <property type="nucleotide sequence ID" value="XM_028671786.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSX3"/>
    <dbReference type="GeneID" id="39731326"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00279300"/>
    <dbReference type="OMA" id="LLKQVHM"/>
    <dbReference type="OrthoDB" id="371439at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="179" mass="21355" checksum="325FC4D51783D21A" modified="2017-02-15" version="1">MKRYINNNKLYNLKKVKVECEYENELKKECTSSIFDFNKVSKKEENIDENNLEKFNIFNLEENGKRRKIDIMHIFNELKNSTQMNEDLLNQNIDKNLVRNKNELVTKCIKNNVNNNIKDKNSNSNENLNKDTSVEKIENCKTKKSNNLNKYYEKINNLLKEIHLSKIARNNNKNIKYMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT18</accession>
    <name>A0A1J1GT18_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00284900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528460.1">
        <property type="nucleotide sequence ID" value="XM_028671848.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT18"/>
    <dbReference type="GeneID" id="39731382"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00284900"/>
    <dbReference type="OMA" id="YLYCFCK"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="76" mass="9187" checksum="83709BA1609296C0" modified="2017-02-15" version="1">MKLLKSILYKVLKKNDNFFHFSKLLLAIKDPFIFFFLCLFLFVLTSLITYIYCLLKSYKSNKDMRIHNINEKSKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT30</accession>
    <name>A0A1J1GT30_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zinc finger protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00285700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528468.1">
        <property type="nucleotide sequence ID" value="XM_028671857.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT30"/>
    <dbReference type="GeneID" id="39731390"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00285700"/>
    <dbReference type="OMA" id="VSPDYIC"/>
    <dbReference type="OrthoDB" id="106784at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006301">
        <property type="term" value="P:DNA damage tolerance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006513">
        <property type="term" value="P:protein monoubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039577">
        <property type="entry name" value="Rad18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14134">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RAD18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14134:SF3">
        <property type="entry name" value="RING-CH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="3">
        <location>
            <begin position="267"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="2">
        <location>
            <begin position="371"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="603" mass="70542" checksum="C50A7E6A14A4EA4E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT66</accession>
    <name>A0A1J1GT66_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PIR-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00269000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000038">
        <property type="protein sequence ID" value="CRG95488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528297.1">
        <property type="nucleotide sequence ID" value="XM_028671668.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT66"/>
    <dbReference type="GeneID" id="39731220"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00269000"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="330" mass="37729" checksum="A23A7046CE3F8881" modified="2017-02-15" version="1">MFSYSVVIVYIFFFLILIFQYFCNKSFEISNKNLNIVSNLIGARVLTEQQLSPIIRSIRTSSDIPDKLVQLPELRQEALYDKLGKLSSNFTGDNTVEYTTCMSNKNMDIVRSLNTHLEHNSKAYLYNIFSLGSKLEKEFHLYSHDYYISEVMLNGRIFNTEPYTISELSSTFTPFSSTTSSSTSSSSITPATSTVSSLVNNNLSEIVTNFSSISTSLFKNLTTLTPSIETETIITSENNSSLLMPVEHSNLNKECFWFFCDPKNFIALYIPLVVVGRLLFFIYLYKQNTHTRPVSGKSNPKKDIGKRRTHKIDNGYNIHKHSEFPFMHPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTF0</accession>
    <name>A0A1J1GTF0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00270700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000040">
        <property type="protein sequence ID" value="CRG95506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528315.1">
        <property type="nucleotide sequence ID" value="XM_028671687.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTF0"/>
    <dbReference type="GeneID" id="39731238"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00270700"/>
    <dbReference type="OrthoDB" id="9838243at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="447" mass="53057" checksum="0AC24D9077EC887A" modified="2017-02-15" version="1">MRTLILFLKITTFLLLILIYLCFHNCDSYKTLIYKNILQTKNELKSERVLTEGDIAGKKQTNAEGCLEERPLDKKKKKIKWKNPFKYENPHDAWQRDTTPYLRERFNSETSEMDSKWRDEKWNNEWNRISANKVKELSSIFHRRDISKEEKERLIYSAEKELYNLFVKFLDECKTEIIDNKTESESKNEMTDNKTESEYKKEMIDNKTESESKNKMTDNKTESEYKKEMIDIKTESESNKEIIDNKTESESMKEMIDNKTESQSMKETIEDKTESESDKEMIDNKTESESMKEMIDNKTESESNKEMIDNKTESESNKEMINNKTESESMKEMIDNKTESQSMKETIEDKTESESNKEMIDNKTESESMQEMIDNKTESESDKEMIDNKTESESNKEMTDNKTESESKNEMTDNKTESESKNEKGKNKIKNKKSNILKFLFKRFDNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTG4</accession>
    <name>A0A1J1GTG4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ion transport domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00301600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528612.1">
        <property type="nucleotide sequence ID" value="XM_028672017.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTG4"/>
    <dbReference type="GeneID" id="39731549"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00301600"/>
    <dbReference type="OrthoDB" id="377302at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38483">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38483:SF1">
        <property type="entry name" value="ION TRANSPORT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="287" mass="34175" checksum="7B90CCD157D98114" modified="2017-02-15" version="1">MDSFIDEELNSADENEPVLLDISDLLNLKRQKKKNIKEELNYVQKDFNFLKPVEDNYDDNEFLITEKEKTRLKNKEYCSSKYTNYYLNIGSICKNCYKRTCKKLGNIFTHKRRDENFFSYSNTFSSDCFNILANRLYYSKITSYIYFFVLLLNIFILIYCFFTKILNKFVVCSEIFVIFMLFIEVCLRLITEGSNYFYHFDGLFDVTVTIMCFLLLISSGDLKIFNETSIVKTKNKEIEEIISQSLTVLRFSFQLFRTITLFMHHKRTKAPNDNIDFSLLNLPKDDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTI0</accession>
    <name>A0A1J1GTI0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DNA topoisomerase 2</fullName>
            <ecNumber evidence="13">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">PGAL8A_00305000</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12 13">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="13">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the type II topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="13"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528646.1">
        <property type="nucleotide sequence ID" value="XM_028672055.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731583"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00305000"/>
    <dbReference type="OMA" id="DVKPHMI"/>
    <dbReference type="OrthoDB" id="276498at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000819">
        <property type="term" value="P:sister chromatid segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16930">
        <property type="entry name" value="HATPase_TopII-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00187">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03481">
        <property type="entry name" value="TopoIIA_Trans_ScTopoIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03365">
        <property type="entry name" value="TOPRIM_TopoIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.40:FF:000003">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.30:FF:000001">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000008">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000004">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.670:FF:000001">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.199.10:FF:000002">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.670">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.199.10">
        <property type="entry name" value="Topoisomerase II, domain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.268.10">
        <property type="entry name" value="Topoisomerase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050634">
        <property type="entry name" value="DNA_Topoisomerase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001241">
        <property type="entry name" value="Topo_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013758">
        <property type="entry name" value="Topo_IIA_A/C_ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013757">
        <property type="entry name" value="Topo_IIA_A_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013759">
        <property type="entry name" value="Topo_IIA_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013506">
        <property type="entry name" value="Topo_IIA_bsu_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002205">
        <property type="entry name" value="Topo_IIA_dom_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001154">
        <property type="entry name" value="TopoII_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018522">
        <property type="entry name" value="TopoIIA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031660">
        <property type="entry name" value="TOPRIM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034157">
        <property type="entry name" value="TOPRIM_TopoII"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10169:SF38">
        <property type="entry name" value="DNA TOPOISOMERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10169">
        <property type="entry name" value="DNA TOPOISOMERASE/GYRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00204">
        <property type="entry name" value="DNA_gyraseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00521">
        <property type="entry name" value="DNA_topoisoIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16898">
        <property type="entry name" value="TOPRIM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01158">
        <property type="entry name" value="TOPISMRASEII"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00418">
        <property type="entry name" value="TPI2FAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00433">
        <property type="entry name" value="TOP2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00434">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="Type II DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52040">
        <property type="entry name" value="TOPO_IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00177">
        <property type="entry name" value="TOPOISOMERASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10 12 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11 12 13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12 13" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Toprim" evidence="16">
        <location>
            <begin position="482"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="domain" description="Topo IIA-type catalytic" evidence="17">
        <location>
            <begin position="728"/>
            <end position="1179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="262"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1247"/>
            <end position="1267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1475"/>
            <end position="1540"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="1142"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="262"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="274"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="1475"/>
            <end position="1493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="1516"/>
            <end position="1528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="1530"/>
            <end position="1540"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="12">
        <location>
            <position position="818"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS52040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="CRG95838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1540" mass="177183" checksum="0089EC13C3FDC036" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTN5</accession>
    <name>A0A1J1GTN5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00280000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528411.1">
        <property type="nucleotide sequence ID" value="XM_028671794.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTN5"/>
    <dbReference type="GeneID" id="39731333"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00280000"/>
    <dbReference type="OrthoDB" id="373044at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="31"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="173" mass="20658" checksum="829E2E60198E7129" modified="2017-02-15" version="1">MEYNINNNIQELTNVKDVEKENVDIKMDNKNELKINEYDELQNEVNKMIERNRMYLNLTNNKTISNNKHNITVKPIRRTYNKFKNISKNKNLTEMTQAGRELEKKMLEEISERRKKNKIKKEKKKAKKLEGELKVGNMTVIKDLSKIRKCDKKTKNKIYKLSSEVINKILKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTP7</accession>
    <name>A0A1J1GTP7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Choline transporter-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ISC3</name>
        <name evidence="8" type="ORF">PGAL8A_00303500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Choline transporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the CTL (choline transporter-like) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528631.1">
        <property type="nucleotide sequence ID" value="XM_028672038.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTP7"/>
    <dbReference type="GeneID" id="39731568"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00303500"/>
    <dbReference type="OMA" id="KEEFYYG"/>
    <dbReference type="OrthoDB" id="420519at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007603">
        <property type="entry name" value="Choline_transptr-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385:SF14">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04515">
        <property type="entry name" value="Choline_transpo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="282"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="311"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="350"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="398"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="452"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="513"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="617"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="658"/>
            <end position="677"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU368066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="729" mass="85340" checksum="7C6D42C025FD17A9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTW1</accession>
    <name>A0A1J1GTW1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DUF726-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00316100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMCO4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528756.1">
        <property type="nucleotide sequence ID" value="XM_028672177.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTW1"/>
    <dbReference type="GeneID" id="39731694"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00316100"/>
    <dbReference type="OMA" id="RYMEWKL"/>
    <dbReference type="OrthoDB" id="277931at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007941">
        <property type="entry name" value="DUF726"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17920:SF3">
        <property type="entry name" value="TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17920">
        <property type="entry name" value="TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 TMCO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05277">
        <property type="entry name" value="DUF726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="664"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="702"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="875"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="448"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="483"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="996" mass="113936" checksum="337EA08949B72B26" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTX5</accession>
    <name>A0A1J1GTX5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00188900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000026">
        <property type="protein sequence ID" value="CRG94494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527312.1">
        <property type="nucleotide sequence ID" value="XM_028670573.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTX5"/>
    <dbReference type="GeneID" id="39730416"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00188900"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="206" mass="25017" checksum="3EE0BE605EE47560" modified="2017-02-15" version="1">MKTLTSYLKITTFLLLIWMYQCFYNCHSHKILIDKNILQTKNELKYERILTEGNTEEKKQTNAEECLKECPLDNEKKESSFPDLYKNPYNYWLKFKVPKYWDRFKNGTSGMDPKWKVKKWNVEFQIISNKKFNELYSIFCRHDIPDEQKNEKIDSFMIEFDSEFDKFLWECKEEMTINKTESESKKEMTDNITESESKKEMTDNKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU10</accession>
    <name>A0A1J1GU10_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transporter, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00318300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528778.1">
        <property type="nucleotide sequence ID" value="XM_028672203.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU10"/>
    <dbReference type="GeneID" id="39731716"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00318300"/>
    <dbReference type="OMA" id="IRIFIIP"/>
    <dbReference type="OrthoDB" id="372777at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd06174">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24064">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="32"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="494"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="530"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="563"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="801"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="840"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="872"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="904"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="937"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="966"/>
            <end position="988"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1034" mass="123678" checksum="BB93DBCFF7B130DA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU61</accession>
    <name>A0A1J1GU61_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">SF-assemblin, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00304500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SF-assemblin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528641.1">
        <property type="nucleotide sequence ID" value="XM_028672049.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU61"/>
    <dbReference type="GeneID" id="39731578"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00304500"/>
    <dbReference type="OMA" id="EHTANDM"/>
    <dbReference type="OrthoDB" id="436841at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008374">
        <property type="entry name" value="SF_assemblin/giardin_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40412">
        <property type="entry name" value="SF-ASSEMBLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40412:SF1">
        <property type="entry name" value="SF-ASSEMBLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06705">
        <property type="entry name" value="SF-assemblin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01799">
        <property type="entry name" value="SFASSEMBLIN"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="266" mass="31309" checksum="C860AC44EC977D0A" modified="2017-02-15" version="1">MIENSESSNISDENFPYDLNISRNKIHDVNFLNESSFFEEKKNKKIDGENFYQEIKYDILRIERNINTEVKKRIEANKNIQQLIEHMANDMINNVLNKITTKIENISIDLDKIIKRCEELEKIIGEIKVDLPTKIQTEMISLKREISDFQIVVNKYINNKKKRDNILYGKIENISAYICSKIQSEICFKQEDLIALKNESEKLLNYDYNEDINFKNIFIEEIEEIKDALALTIKAREQSDDDIIQAMNKYTNVLQKALQSVIINNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU70</accession>
    <name>A0A1J1GU70_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00327600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000054">
        <property type="protein sequence ID" value="CRG96060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528868.1">
        <property type="nucleotide sequence ID" value="XM_028672302.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU70"/>
    <dbReference type="GeneID" id="39731806"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00327600"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="941"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="965" mass="117276" checksum="A5448668AFF38A66" modified="2017-02-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUA6</accession>
    <name>A0A1J1GUA6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Succinyl-CoA ligase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00309300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528689.1">
        <property type="nucleotide sequence ID" value="XM_028672103.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUA6"/>
    <dbReference type="GeneID" id="39731626"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00309300"/>
    <dbReference type="OMA" id="SEMVCEL"/>
    <dbReference type="OrthoDB" id="1664372at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043758">
        <property type="term" value="F:acetate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000066">
        <property type="entry name" value="Acetyl coenzyme A synthetase (ADP forming), alpha domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000512">
        <property type="entry name" value="Acetyl coenzyme A synthetase (ADP forming), alpha domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051538">
        <property type="entry name" value="Acyl-CoA_Synth/Transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043938">
        <property type="entry name" value="Ligase_CoA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032875">
        <property type="entry name" value="Succ_CoA_lig_flav_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43334:SF1">
        <property type="entry name" value="3-HYDROXYPROPIONATE--COA LIGASE [ADP-FORMING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43334">
        <property type="entry name" value="ACETATE--COA LIGASE [ADP-FORMING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13549">
        <property type="entry name" value="ATP-grasp_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13380">
        <property type="entry name" value="CoA_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19045">
        <property type="entry name" value="Ligase_CoA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13607">
        <property type="entry name" value="Succ_CoA_lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CoA-binding" evidence="4">
        <location>
            <begin position="39"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="982" mass="112744" checksum="9D3503EA0C550C1B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUH5</accession>
    <name>A0A1J1GUH5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Kelch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00316600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528761.1">
        <property type="nucleotide sequence ID" value="XM_028672182.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUH5"/>
    <dbReference type="GeneID" id="39731699"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00316600"/>
    <dbReference type="OMA" id="NFGSIYM"/>
    <dbReference type="OrthoDB" id="10250130at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036202">
        <property type="entry name" value="TopoI_DNA-bd_euk_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23244:SF488">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23244">
        <property type="entry name" value="KELCH REPEAT DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56741">
        <property type="entry name" value="Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="822" mass="97434" checksum="F5E6937C1E526900" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUJ7</accession>
    <name>A0A1J1GUJ7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCZ1/INTU/HSP4 first Longin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00334500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CCZ1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528935.1">
        <property type="nucleotide sequence ID" value="XM_028672376.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUJ7"/>
    <dbReference type="GeneID" id="39731875"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00334500"/>
    <dbReference type="OMA" id="GPWIFAK"/>
    <dbReference type="OrthoDB" id="240546at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035658">
        <property type="term" value="C:Mon1-Ccz1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013176">
        <property type="entry name" value="Ccz1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043987">
        <property type="entry name" value="CCZ1/INTU/HSP4_longin_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13056">
        <property type="entry name" value="VACUOLAR FUSION PROTEIN CCZ1 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13056:SF0">
        <property type="entry name" value="VACUOLAR FUSION PROTEIN CCZ1 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19031">
        <property type="entry name" value="Intu_longin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCZ1/INTU/HSP4 first Longin" evidence="3">
        <location>
            <begin position="9"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="474"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="482"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="648" mass="76055" checksum="6E94303BE899E879" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUR4</accession>
    <name>A0A1J1GUR4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Golgi apparatus membrane protein TVP23 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">TVP23</name>
        <name evidence="7" type="ORF">PGAL8A_00218200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the TVP23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527600.1">
        <property type="nucleotide sequence ID" value="XM_028670893.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUR4"/>
    <dbReference type="GeneID" id="39730709"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00218200"/>
    <dbReference type="OMA" id="KMIWWID"/>
    <dbReference type="OrthoDB" id="2151161at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008564">
        <property type="entry name" value="TVP23-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13019">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13019:SF7">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05832">
        <property type="entry name" value="DUF846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG94785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="227" mass="27432" checksum="1B9C507C06404CC5" modified="2017-02-15" version="1">MNNNIFESNENEDKKLKFPSRIDDVMSIPHTNSNNFNSINRNEFNNYLNFFFQNIKHPYICFVHILFKFLSLFFYFLGPLIFRNEKSKENDFIITFATTFFLVSLDFYLVKNITGRFLVKMTWWIDMSDDYSNKIIFKSLEDNLINKLDKNIFWYSLYINFFIWLIQTIQMLISLQICWFLLCFLCLFLSFYNLFNFCKCSREQYKVVGNVLDQINLNAIFKGVFSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV14</accession>
    <name>A0A1J1GV14_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00361700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529198.1">
        <property type="nucleotide sequence ID" value="XM_028672669.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732147"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00361700"/>
    <dbReference type="OMA" id="CSIFNIY"/>
    <dbReference type="OrthoDB" id="376316at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031431">
        <property type="term" value="C:Dbf4-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043539">
        <property type="term" value="F:protein serine/threonine kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010571">
        <property type="term" value="P:positive regulation of nuclear cell cycle DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901987">
        <property type="term" value="P:regulation of cell cycle phase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051590">
        <property type="entry name" value="Replication_Regulatory_Kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15375">
        <property type="entry name" value="ACTIVATOR OF S-PHASE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15375:SF26">
        <property type="entry name" value="PROTEIN CHIFFON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1434"/>
            <end position="1454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1468"/>
            <end position="1492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1434"/>
            <end position="1448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1468"/>
            <end position="1487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1766" mass="211820" checksum="5B79184B76739CFE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV52</accession>
    <name>A0A1J1GV52_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">G-beta repeat protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00258100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527989.1">
        <property type="nucleotide sequence ID" value="XM_028671326.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV52"/>
    <dbReference type="GeneID" id="39731109"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00258100"/>
    <dbReference type="OMA" id="CLWKYNY"/>
    <dbReference type="OrthoDB" id="10248252at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013979">
        <property type="entry name" value="TIF_beta_prop-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10971">
        <property type="entry name" value="MRNA EXPORT FACTOR AND BUB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08662">
        <property type="entry name" value="eIF2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Translation initiation factor beta propellor-like" evidence="3">
        <location>
            <begin position="10"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="362" mass="41329" checksum="5F9960AE95C311DE" modified="2017-02-15" version="1">MNIQNKPQIIEHINYSVDNTIYDVKWIDEKSKIVAVGELLDKKGYINIYNLNKGKFTCDSSNKTNNGIKTVTPFYSYTGNYTLACGSFDGSILLYDIHNLSKEYYKIKKHNKLINKIDCKSYKNNNIIVTASRDGSVKIFDIRTYQDVVSLEPPKNSAYIPDCWCVATGNNYIEENSCGIGEENFNICAGYDNGDIKFFDLKMMNLEHEVNVNNGVCSISYDRKETKKNKLICSTLEGNIYLFNLDVYSEDAGYSYRKDKIISGTCWGTPFLPQNRDIFALLGGDGNLILYKYIYPEKNHVFDETKGCKRGIIGELDKLNYLNISTQPIISFDWNRQKLGLCALASLDQTIKVYIITKLNLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV95</accession>
    <name>A0A1J1GV95_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">ER membrane protein Sec12, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00343000</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529017.1">
        <property type="nucleotide sequence ID" value="XM_028672468.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV95"/>
    <dbReference type="GeneID" id="39731960"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00343000"/>
    <dbReference type="OMA" id="DDRPCCN"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003400">
        <property type="term" value="P:regulation of COPII vesicle coating"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045260">
        <property type="entry name" value="Sec12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23284">
        <property type="entry name" value="PROLACTIN REGULATORY ELEMENT BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23284:SF0">
        <property type="entry name" value="PROLACTIN REGULATORY ELEMENT-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="3 11" id="KW-0853">WD repeat</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="365"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="116"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="168"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG96212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="417" mass="48211" checksum="316C0FB16E3F0C69" modified="2017-02-15" version="1">MNEIKVSYLNYPIYGIASNENYVVTSGGGGGKSYGIEDLLDVNIFNEKEKKLDVIWSTTEQKGVIDSILYVQKYNIWIGSLKNECILFKINEETGPSILLNFITDFAEKNPRQVVVKFSENQDFILTGGDDKTLRLWKLKFTKDSSFIHVTNDLYLDSKTAVEHLGDFIGHDESIKDCDITFDENIVCTCSSDYSLKIWDTYRYINLHTEFMKNPKNKNDKLIFRCCKFLKKSNIIREYTYSLLTTASSARGNSFLIIWNIYYDNKKEKFSCVKQNLIWIDETPCCNMAISTNENFLALGFSTGSLKLYNSKYSLLAYYKKHELPITAMCFTKNDKFLLAAGADYSISCVDVNCLSFRFKKIWKFFIFLFISLIIFIILLDCFNVGYDLHVNSPTTDKLKFSKIDIIKQKNQPFDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVD8</accession>
    <name>A0A1J1GVD8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta-hydrolase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00240800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527824.1">
        <property type="nucleotide sequence ID" value="XM_028671142.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVD8"/>
    <dbReference type="GeneID" id="39730936"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00240800"/>
    <dbReference type="OMA" id="CNCGVRT"/>
    <dbReference type="OrthoDB" id="2498029at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051044">
        <property type="entry name" value="MAG_DAG_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11614">
        <property type="entry name" value="PHOSPHOLIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="2">
        <location>
            <begin position="602"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="377"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1052" mass="123352" checksum="FF0296919A02B179" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVE0</accession>
    <name>A0A1J1GVE0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ubiquitin activating enzyme (E1) subunit Aos1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AOS1</name>
        <name evidence="2" type="ORF">PGAL8A_00372000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529300.1">
        <property type="nucleotide sequence ID" value="XM_028672782.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVE0"/>
    <dbReference type="GeneID" id="39732250"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00372000"/>
    <dbReference type="OMA" id="EFFGQFD"/>
    <dbReference type="OrthoDB" id="412647at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031510">
        <property type="term" value="C:SUMO activating enzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019948">
        <property type="term" value="F:SUMO activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF162">
        <property type="entry name" value="SUMO-ACTIVATING ENZYME SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="1">
        <location>
            <begin position="13"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="338" mass="39843" checksum="FB7D9652CAD8D487" modified="2017-02-15" version="1">MRDNEEWEKEKIYDRQLRLWGVKAQNRMMKSNVLIIGLSGINIEICKNLILNGINITIIDDNIVDEEMRENIFFLDESDNGKYVCLSIFKELKSINQLININAYIGRIDIVNDNIILDKHLIYKEEGIENEEINECFNINNFINNYTSVCISCEDYPLYKLININEICHEKNIGFFAPMCNGKYAFLFSDFGNHTIEESYYKTKKNDEKSNKLIEIEYCKLSHFLKVSFKNFHKKTNHIIFYMFALILFEQHKEFSKDKKEIDEKEFYNFCNEFALNNDEILKEITKMYKVTFSPSCSIMGGITAQEIRKFVSKQHEPIPNFCVFDMNQNIACTAMIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVN8</accession>
    <name>A0A1J1GVN8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00011300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528157.1">
        <property type="nucleotide sequence ID" value="XM_028671512.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVN8"/>
    <dbReference type="GeneID" id="39728635"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00011300"/>
    <dbReference type="OMA" id="NRSTRLW"/>
    <dbReference type="OrthoDB" id="368753at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="97"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="136" mass="16033" checksum="040D9DED5472F6D4" modified="2017-02-15" version="1">MGKSFYNRSTRLWWGHCHLRIGSRLQVRLNKGIKFSHFEHIGRFIAFARRSRSLRAASLSKCLRRNYWGTSFYYDGKPKTEENPQQILKSSQDEGGYIYAIEKGKIIPSEKEMKKLESILGVPLKREKQKTLLRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW07</accession>
    <name>A0A1J1GW07_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00367100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529251.1">
        <property type="nucleotide sequence ID" value="XM_028672727.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW07"/>
    <dbReference type="GeneID" id="39732201"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00367100"/>
    <dbReference type="OMA" id="NTNWGLY"/>
    <dbReference type="OrthoDB" id="386526at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="272"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="534"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="34"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="275"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="332"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="534"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="767" mass="92397" checksum="5D357953D897545F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW25</accession>
    <name>A0A1J1GW25_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CRAL-TRIO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00433600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529558.1">
        <property type="nucleotide sequence ID" value="XM_028673068.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW25"/>
    <dbReference type="GeneID" id="39732868"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00433600"/>
    <dbReference type="OMA" id="FILWRQM"/>
    <dbReference type="OrthoDB" id="75724at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008526">
        <property type="term" value="F:phosphatidylinositol transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052578">
        <property type="entry name" value="PI_Transfer_CRAL-TRIO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45824">
        <property type="entry name" value="GH16843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45824:SF29">
        <property type="entry name" value="GH16843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="272"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="490" mass="58966" checksum="25ADF7285B41D23E" modified="2017-02-15" version="1">MSDNESFISIENNNDEVKNNENKTNLNLDNFLDYNIDYMNDVEKYNYIGVDILQRPDYFEIKKDKIEFFVNDQMSDINNALHSRKKEEIDIFLKIKKELYNIAYKNHHNQLNINNNDNNNLVDEKNKMINENSKIINESVKLEKSNNKNEDKNKKSYDILNNDLSMTLGNKIEDTYNEIKSSVNWLGNFFSNNENYEKKKNLNIFYKDLYFFNDTTIIRFLDTYNYNMLKTLNKIIKCILWRQMSIIHYNNKQDTLNNSNNTTNNNNIFVNPKNLRNSLMKMNIFRCGYDLKSRPLLYIKIQEKLDIKEEELILMLVYHVDMCMNSVDYKKCYQKNNNLDNSEKIKFDESSLQLVIVVDCLKFDLNNMISVDCIKKIINIFNEFYTDVLYRIYIINVPSFFKKVWSLFNMFIDNHTLKKIIIINKKNINLMYEHIISNFMMHFDRTSEKKDESSIFFPSNTLYYKYDEKYYEKLVGYVNIWVDKMIKVNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW47</accession>
    <name>A0A1J1GW47_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00423900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529463.1">
        <property type="nucleotide sequence ID" value="XM_028672962.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW47"/>
    <dbReference type="GeneID" id="39732771"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00423900"/>
    <dbReference type="OMA" id="KYYDENC"/>
    <dbReference type="OrthoDB" id="360784at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="963" mass="114277" checksum="6227CA7B6CDCECA9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW65</accession>
    <name>A0A1J1GW65_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Telomeric repeat binding factor 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">TRF1</name>
        <name evidence="2" type="ORF">PGAL8A_00437650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529598.1">
        <property type="nucleotide sequence ID" value="XM_028673113.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW65"/>
    <dbReference type="GeneID" id="39732909"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00437650"/>
    <dbReference type="OMA" id="KTRVKWD"/>
    <dbReference type="OrthoDB" id="608866at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042162">
        <property type="term" value="F:telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031848">
        <property type="term" value="P:protection from non-homologous end joining at telomere"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11660">
        <property type="entry name" value="SANT_TRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030657">
        <property type="entry name" value="TERF2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46833:SF1">
        <property type="entry name" value="TELOMERIC REPEAT-BINDING FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46833">
        <property type="entry name" value="TELOMERIC REPEAT-BINDING FACTOR 2 TERF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="1">
        <location>
            <begin position="47"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="104" mass="12488" checksum="F39F0333753FF370" modified="2017-02-15" version="1">MELTDIQLLKIKSSIFMDEDSSPILIDTNKIKKKDKKKKEKIKYKTRVKWTQKEIELLINGINTYGLSNWSKIMNSYSFPEYRTNTSLKDKYRNFKKVFIIEKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW66</accession>
    <name>A0A1J1GW66_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thioredoxin 3, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">TRX3</name>
        <name evidence="3" type="ORF">PGAL8A_00429000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529514.1">
        <property type="nucleotide sequence ID" value="XM_028673019.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW66"/>
    <dbReference type="GeneID" id="39732822"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00429000"/>
    <dbReference type="OMA" id="GATWCKP"/>
    <dbReference type="OrthoDB" id="2121326at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050620">
        <property type="entry name" value="Thioredoxin_H-type-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10438">
        <property type="entry name" value="THIOREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10438:SF405">
        <property type="entry name" value="THIOREDOXIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="82"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="177" mass="21023" checksum="697B255B68BD8D83" modified="2017-02-15" version="1">MALICIGSVCFSLFHIGIIILFIINYFSSHLKKLFYHFFPNNNELDSEIKSILQLKKKNKEYEESRYIELQKNECLKEIFSSTKNLSVVLKFSSMWCKPCNNVKEYFKSQTDFFDVTLVSIDVDIHKKLMESHKIRALPTFEFYFLLKNEWIITCRIEGGNKNEIEKAFQKYCLPKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW89</accession>
    <name>A0A1J1GW89_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00431500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529538.1">
        <property type="nucleotide sequence ID" value="XM_028673046.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW89"/>
    <dbReference type="GeneID" id="39732847"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00431500"/>
    <dbReference type="OMA" id="LKMCKEN"/>
    <dbReference type="OrthoDB" id="373008at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="474" mass="54928" checksum="28391F48C2E57858" modified="2017-02-15" version="1">MKNDNISEREALLKYKLNNSKKKLDRGWKEKVLAIIKKGNKNDVPQHGVSSHTNTKSTSIFNFGKFKIFGRSKNMYKTKSNNRKESSINSDNAKKNMEKFSLIKQSSCDNKLIINRSIRNNFNKKSTIKIPKNDIKEFKKSLSSIKTKVGTRYLDNDKKNSEHSTKGNYNNSNLNNNSNKLHLMKSFEKNKIVTPFKDSKKNINITEDKPLLKNTVKIEMKNFPKNSINNNNLKRKELIDFNNNENEDYDNDKLNFSSEKTINKLNDEKASLNKTKNEKFLLSKKTNMSMELKKTYSKDLENSNIKINKICCDVNNNKNSNIINNLKLKKNDIVKRANMVVKKQKITTDELLDANNIKNLRRINTKELMSMDVPFKIDPPNLFCEYAYNISPVSPIEERIDMIYSILNNHKNEIITLLKLCIDNNKQCSEILKIILDALIEGEDSIVSKLNKNKPLQDEIIMELEQVLESVNED</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWA4</accession>
    <name>A0A1J1GWA4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine/threonine protein kinase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00441600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529638.1">
        <property type="nucleotide sequence ID" value="XM_028673157.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWA4"/>
    <dbReference type="GeneID" id="39732949"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00441600"/>
    <dbReference type="OMA" id="NDMHIWY"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053083">
        <property type="entry name" value="TF_kinase-domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44305">
        <property type="entry name" value="SI:DKEY-192D15.2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44305:SF24">
        <property type="entry name" value="TYROSINE-PROTEIN KINASE C03B1.5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="181"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="575" mass="70077" checksum="6D3C1F4DC08326AE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWP4</accession>
    <name>A0A1J1GWP4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00455100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529774.1">
        <property type="nucleotide sequence ID" value="XM_028673307.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWP4"/>
    <dbReference type="GeneID" id="39733084"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00455100"/>
    <dbReference type="OMA" id="VWKLLYM"/>
    <dbReference type="OrthoDB" id="378080at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="219"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="249"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="400"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="435"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="472"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="505" mass="60570" checksum="2A497F1DE1348C93" modified="2017-02-15" version="1">MNNSLISQVLTETEIIELGLNNSLMKTCSCPFILNKKYFIKICISYLLIIFLFFSVYITIIILLLNSNKTGLTKPISLIIYIYIFVFFYVDIFISNIIKYDLVKKYNLKEIRKRIYENFLTSQKTDSLKKNKNGKDKKKSENKYKAKNEGEKLFSSEKYYVTNMEENENVSINETKVFEERNYCLDELKNINDFINVELLKYIQYENNNYTINNSKFDIFLTISGLINQLNIFCDLLFLFYLYDFSKNLFIVSLFIYIYYLIHFFVIIKFSIIIIQSLIKIYKKSFSNSLKKTSFYIKDFLSSSYHSVQETLKNFLQTLTLRENHETLNENKSNIFLNKYTNYNSWCFFYKEDYHNDYEIKKFQMKYDSINKYSEKKKKNIIKIKIKKNRNNNKINYEKALMPSYVQFIANTSYFLSFFHILNIMKVKFLSAHNIYSHISFTIVFFVWKLLYMDVVLCLLKFFILFYTDDNLIVAMFLLISIINILNSYLINLLDHNLLNDININ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX00</accession>
    <name>A0A1J1GX00_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00467200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529894.1">
        <property type="nucleotide sequence ID" value="XM_028673442.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX00"/>
    <dbReference type="GeneID" id="39733205"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00467200"/>
    <dbReference type="OMA" id="GSFGIQC"/>
    <dbReference type="OrthoDB" id="269872at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11572">
        <property type="entry name" value="RlmI_M_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="entry name" value="PUA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.80">
        <property type="entry name" value="RNA methyltransferase domain (HRMD) like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041532">
        <property type="entry name" value="RlmI-like_PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42873">
        <property type="entry name" value="RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42873:SF1">
        <property type="entry name" value="S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17785">
        <property type="entry name" value="PUA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RlmI-like PUA" evidence="5">
        <location>
            <begin position="80"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransferase small" evidence="4">
        <location>
            <begin position="331"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="503" mass="58737" checksum="797A02A9DB6FCF83" modified="2017-02-15" version="1">MKYKMLIIKSTKKWKNLKYRLFSNIKFEENVSCFKKNKSKFEKNIKFREELYKYHYEQYIDNVNSRPDLYLKDSEDNNIHDKRLKRNIPFVYSNEVKNLEELKKNPLTLVNVKNMNDESFGVATFNPYSLISARIINQNSMFSININFFIEKIKNSLLWRNKISKNETDNIISSTNHNVMLNTNSTISTASDDNNNANENIHEYPILNSSYCYRLINSEGDNIPGLIIDRYDEYISVQHLTLGCEMLACNINDAIIELLKPKGIIFRNDNKERLNEKLEIYKKVIYGKVPDKVTMIENNCSFFIDLINSPNTGWFFNRKNLRNYICHYSYQKNVLDLFSYVGSFGIQCSKIGKAKKVVCVEKDKNFVHLAKKSANLNNVNNIDFICSDSLSFLKNCNQLFDIIILDPPNLIPKSQFIESGSMRYINLINLAQNYVTPNGLLLIIFTTKLCSYQDYINIINKSFINTNKTVKIVGQGRSSPDNPVNLSLYLFSDFYWFILQLTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX12</accession>
    <name>A0A1J1GX12_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Clathrin adaptor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00467000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529892.1">
        <property type="nucleotide sequence ID" value="XM_028673440.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX12"/>
    <dbReference type="GeneID" id="39733203"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00467000"/>
    <dbReference type="OMA" id="SYRMQDM"/>
    <dbReference type="OrthoDB" id="413467at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013041">
        <property type="entry name" value="Clathrin_app_Ig-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49348">
        <property type="entry name" value="Clathrin adaptor appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="433"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="261"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="435"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1027" mass="123652" checksum="DFCB4CD6AE5EC39A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX97</accession>
    <name>A0A1J1GX97_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00475600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529980.1">
        <property type="nucleotide sequence ID" value="XM_028673538.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX97"/>
    <dbReference type="GeneID" id="39733289"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00475600"/>
    <dbReference type="OMA" id="ACESSER"/>
    <dbReference type="OrthoDB" id="10683242at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="73"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="298"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="532"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="644"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="699"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="807"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="766"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="298"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="412"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="541"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="644"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="674"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="816"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="832"/>
            <end position="841"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="899" mass="108591" checksum="8FA717CA1907B310" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXC8</accession>
    <name>A0A1J1GXC8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcription initiation factor IIA subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00471600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529938.1">
        <property type="nucleotide sequence ID" value="XM_028673491.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXC8"/>
    <dbReference type="GeneID" id="39733249"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00471600"/>
    <dbReference type="OMA" id="KIYKEAC"/>
    <dbReference type="OrthoDB" id="361139at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005672">
        <property type="term" value="C:transcription factor TFIIA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.18.10">
        <property type="entry name" value="Transcription factor IIA (TFIIA), beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009088">
        <property type="entry name" value="TFIIA_b-brl"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50784">
        <property type="entry name" value="Transcription factor IIA (TFIIA), beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="194" mass="23055" checksum="FD037D7A5C1BA3A4" modified="2017-02-15" version="1">MEQGNFDEKFGNSILLEALKEALKQMIEEFYVEKEIGIKIYKQACANIKKEILNNSNQLSDINNIKKEILNNSNQLSDINVSGHLKSYYCRNDIWTFFFKNSLFKINKNKKTKNSSKDYKNYQPLNLRVYKNFNDKKEEFLKYSIDDNNVKILKNFSKLYSNIVHKENNENDIDDIFFYYDGLIKILCVEEAFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXK5</accession>
    <name>A0A1J1GXK5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00487700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530100.1">
        <property type="nucleotide sequence ID" value="XM_028673671.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXK5"/>
    <dbReference type="GeneID" id="39733410"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00487700"/>
    <dbReference type="OMA" id="KNHNENP"/>
    <dbReference type="OrthoDB" id="1748655at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031721">
        <property type="entry name" value="Partial_CstF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15861">
        <property type="entry name" value="partial_CstF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="8"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="724"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="234"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="728"/>
            <end position="779"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="921" mass="108839" checksum="3D85C93266EB6FD5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXK7</accession>
    <name>A0A1J1GXK7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00480200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530026.1">
        <property type="nucleotide sequence ID" value="XM_028673589.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXK7"/>
    <dbReference type="GeneID" id="39733335"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00480200"/>
    <dbReference type="OrthoDB" id="360858at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="350" mass="42562" checksum="ACB6B46FD72EC710" modified="2017-02-15" version="1">MLHYFKYVNIKILLLLLLFILFDNYVENYIFYKGGFIIKPHFKRVFCLKKHKYKKLLFKLKSHEEIDDYKYFTEDEYIPALPPVETWEDLLIKEEIRNKTEDERRNVDDYKLSHESREKVLDIMRQTRLINHCNYEIQKNKQKNILYFVTPKIGPYCKLMENDKNKMDSLVSKVKEKFGKKVEIVNLKLDVKMPLFEIFLQANIHTQIKIFYARGRTLQYRLPSVFWTKCKILKENKILQEKYGGECAPGLFPKYDEYNIMQIITECVYNDKYNYYVYDVNLEWENLCALTPENKELRKIVHQNVHVPTRLAVIKAFEQGIEDFRDVIREEYLIMLREQRKLKENKDYKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXR6</accession>
    <name>A0A1J1GXR6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Signal recognition particle receptor subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00467500</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SRP receptor beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529897.1">
        <property type="nucleotide sequence ID" value="XM_028673446.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXR6"/>
    <dbReference type="GeneID" id="39733208"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00467500"/>
    <dbReference type="OMA" id="MNGVKVT"/>
    <dbReference type="OrthoDB" id="41266at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04105">
        <property type="entry name" value="SR_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019009">
        <property type="entry name" value="SRP_receptor_beta_su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09439">
        <property type="entry name" value="SRPRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="32"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG97094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="262" mass="30951" checksum="E3509C9FCE5A83E6" modified="2017-02-15" version="1">MDILLKILKSIILKLKIYYAKYGIDLNEFHNLLFIITLLFGLVFLFYLIFIIFSIFKKRKKIKQEIVLLLGPCDSGKTTFLFKLKTNKICRTITSMKENKAFIFLKNKKKQKCIQFVDFPGHPKLSHSLNKYFDFTKIIIYILDSSDKQSLKIVAEKLYELFTNKIIVQKKIPFIIVCNKTDLCNSRPKQVIKEDLEREIEILKMSKYNSLEEDDNDETEHFLGSNSEFFRFEKAPCHIEICSASIKNDYVEEIIEFIEKHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXU2</accession>
    <name>A0A1J1GXU2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">40S ribosomal protein S4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00332700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the eukaryotic ribosomal protein eS4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528917.1">
        <property type="nucleotide sequence ID" value="XM_028672357.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXU2"/>
    <dbReference type="GeneID" id="39731857"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00332700"/>
    <dbReference type="OMA" id="GHIQLNL"/>
    <dbReference type="OrthoDB" id="1109245at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06087">
        <property type="entry name" value="KOW_RPS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000041">
        <property type="entry name" value="40S ribosomal protein S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.740:FF:000001">
        <property type="entry name" value="40S ribosomal protein S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.290.10:FF:000019">
        <property type="entry name" value="40S ribosomal protein S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="entry name" value="RNA-binding S4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00485">
        <property type="entry name" value="Ribosomal_eS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000876">
        <property type="entry name" value="Ribosomal_eS4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032277">
        <property type="entry name" value="Ribosomal_eS4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013845">
        <property type="entry name" value="Ribosomal_eS4_central_region"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038237">
        <property type="entry name" value="Ribosomal_eS4_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041982">
        <property type="entry name" value="Ribosomal_eS4_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013843">
        <property type="entry name" value="Ribosomal_eS4_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018199">
        <property type="entry name" value="Ribosomal_eS4_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11581">
        <property type="entry name" value="30S/40S RIBOSOMAL PROTEIN S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11581:SF0">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN ES4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16121">
        <property type="entry name" value="40S_S4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00900">
        <property type="entry name" value="Ribosomal_S4e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08071">
        <property type="entry name" value="RS4NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002116">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00528">
        <property type="entry name" value="RIBOSOMAL_S4E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="KOW" evidence="7">
        <location>
            <begin position="174"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="261" mass="29812" checksum="D2AAEE638123CD19" modified="2017-02-15" version="1">MGKGIKKHLKRVNAPSHWMLNKMGGQYAPKTSSGPHKLIESIPLVILLRNRLKYALTFDEVKLILIQKIVKVDNKIRTDCTFPVGLMDVIHITKSNEYFRLLYDVKGRFVPHRITKEESQYKLCKVKKIILRKGRLPIAITHDGRSIPYIHPEIKVNDTIRLDLETGKVLEFLKFQVGSLVMVTGGHSVGRVGVISSIDKNIGTYDIIHVKDSRNKVFATRLSNVFVIGDNTKPYISLPREKGIKLDIIEERRNRLKALNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXY7</accession>
    <name>A0A1J1GXY7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Endoplasmic reticulum-resident calcium binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ERC</name>
        <name evidence="5" type="ORF">PGAL8A_00335900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528949.1">
        <property type="nucleotide sequence ID" value="XM_028672392.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXY7"/>
    <dbReference type="GeneID" id="39731889"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00335900"/>
    <dbReference type="OMA" id="PLSNKEH"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10827:SF85">
        <property type="entry name" value="CALCIUM-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10827">
        <property type="entry name" value="RETICULOCALBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012227318" evidence="3">
        <location>
            <begin position="23"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="54"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="90"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="130"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="167"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="204"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="299"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="307"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="341" mass="39418" checksum="64627F53DB7DFE65" modified="2017-02-15" version="1">MIAYIYFLVISCVFYLKQNANADHMKYTDMKGLDDLSHLSNEKVMDILGMNIQGAKERLEKIFHIIDKNNDMILSDAELEIWSNFVKNEVFLKQVQVEMKQIDSDKDGFISLAELNDAFSQNLDEKEVEKHSEGLLKRFQIVDKDKDSKLNINEVGLLIDPVKDEELKELEISEILDHHDINKDGKISLEEFKQTRTDDPNSKKDDDVALDDFNFFDSNKDGFIDKEEIIKVYFDPSHETGSININEIKDGIFEGKEISYDLWNEKALKIAVTSLTDYGDIIRFPEDFKLDIGKNVVLPSSKGHVSEEEDLDQDELETEDNKNEEQENDETEEKEPTTDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYD9</accession>
    <name>A0A1J1GYD9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">mRNA-decapping enzyme 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">DCP2</name>
        <name evidence="12" type="ORF">PGAL8A_00505000</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Nudix hydrolase family. DCP2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530278.1">
        <property type="nucleotide sequence ID" value="XM_028673869.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733583"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00505000"/>
    <dbReference type="OMA" id="KNWNNNG"/>
    <dbReference type="OrthoDB" id="18996at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140933">
        <property type="term" value="F:5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03672">
        <property type="entry name" value="NUDIX_Dcp2p_Nudt20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.79.10:FF:000045">
        <property type="entry name" value="mRNA-decapping enzyme 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1050">
        <property type="entry name" value="Dcp2, box A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007722">
        <property type="entry name" value="DCP2_BoxA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036189">
        <property type="entry name" value="DCP2_BoxA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044099">
        <property type="entry name" value="Dcp2_NUDIX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23114">
        <property type="entry name" value="M7GPPPN-MRNA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23114:SF17">
        <property type="entry name" value="M7GPPPN-MRNA HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05026">
        <property type="entry name" value="DCP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01125">
        <property type="entry name" value="DCP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140586">
        <property type="entry name" value="Dcp2 domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0464">Manganese</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="11">
        <location>
            <begin position="133"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1241"/>
            <end position="1272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1241"/>
            <end position="1251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1252"/>
            <end position="1272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG97477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1302" mass="153194" checksum="260AF4BD69307C9F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYE7</accession>
    <name>A0A1J1GYE7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00515300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530381.1">
        <property type="nucleotide sequence ID" value="XM_028673983.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYE7"/>
    <dbReference type="GeneID" id="39733686"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00515300"/>
    <dbReference type="OMA" id="ENYCTAK"/>
    <dbReference type="OrthoDB" id="378228at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="587"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="595"/>
            <end position="612"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="673" mass="79846" checksum="088398BD77ACC210" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYG1</accession>
    <name>A0A1J1GYG1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00354600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529133.1">
        <property type="nucleotide sequence ID" value="XM_028672596.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYG1"/>
    <dbReference type="GeneID" id="39732076"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00354600"/>
    <dbReference type="OrthoDB" id="10524924at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="218" mass="26306" checksum="AA059D38C5865977" modified="2017-02-15" version="1">MFNFDKNFEEKFAVAIETPLKNNIYEYSCMENIINKSSKCYLNNCNLKKLEENSNIRLIEKSDTQYEISNSLYKKFLENSYMKKCDLTDFDKKKQDILEKKINEIYYWENKIKNLSKKKKIAIKNKVKSHLELMKYNDSRKKLEKIEYLKNNKINEQLAILARAEYAKEVIERNIKSKKIVKEDNINFVILSLENLKKHIEYTYLNKEKEKKNNFFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYH8</accession>
    <name>A0A1J1GYH8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mitochondrial ribosomal protein S35, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00508500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530313.1">
        <property type="nucleotide sequence ID" value="XM_028673907.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYH8"/>
    <dbReference type="GeneID" id="39733618"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00508500"/>
    <dbReference type="OrthoDB" id="5307821at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019349">
        <property type="entry name" value="Ribosomal_mS35_mit"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10213">
        <property type="entry name" value="MRP-S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein mS35 mitochondrial conserved" evidence="1">
        <location>
            <begin position="184"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="256" mass="30816" checksum="DEF964002F23D5A3" modified="2017-02-15" version="1">MIIIKKWDILKPKTLLFNWNKYFGNILINNDKYKDLNTKKPYYMFNQIRWKKNRKKRERINLNEEQKNTKLKIPPIRLEDRTTVCETPTVISKNIRNEIMKVCVGKERTRRHFKFRNKYRIKKLLSLTHDKENVKHNNPSTFITPLTKLQHESTLPRTLNHDRFNFPHSFQYSVTWHGSSIVDNEENNICFFSSNINDLLLSPKEKRKLIEILGEERVDLKNNLIYLESNFFNTYNHNAAYLGDAVQFLMKRIKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYQ4</accession>
    <name>A0A1J1GYQ4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00517000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530398.1">
        <property type="nucleotide sequence ID" value="XM_028674002.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733703"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00517000"/>
    <dbReference type="OrthoDB" id="360742at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="328"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="940"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="7"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="83"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="171"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="348"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="366"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="389"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="417"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="950"/>
            <end position="962"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1303" mass="154957" checksum="40F06D2C1560CE30" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYZ6</accession>
    <name>A0A1J1GYZ6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FbpA domain protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00535800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530581.1">
        <property type="nucleotide sequence ID" value="XM_028674205.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYZ6"/>
    <dbReference type="GeneID" id="39733891"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00535800"/>
    <dbReference type="OrthoDB" id="436717at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990112">
        <property type="term" value="C:RQC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072344">
        <property type="term" value="P:rescue of stalled ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990116">
        <property type="term" value="P:ribosome-associated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.310.10">
        <property type="entry name" value="ibrinogen binding protein from staphylococcus aureus domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008532">
        <property type="entry name" value="NFACT_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051608">
        <property type="entry name" value="RQC_Subunit_NEMF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15239">
        <property type="entry name" value="NUCLEAR EXPORT MEDIATOR FACTOR NEMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15239:SF6">
        <property type="entry name" value="RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT NEMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05670">
        <property type="entry name" value="NFACT-R_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05833">
        <property type="entry name" value="NFACT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NFACT RNA-binding" evidence="2">
        <location>
            <begin position="644"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="86"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="782" mass="93305" checksum="B41F1FD278C78829" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ17</accession>
    <name>A0A1J1GZ17_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00347700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529064.1">
        <property type="nucleotide sequence ID" value="XM_028672519.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732007"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00347700"/>
    <dbReference type="OMA" id="ELKRWVI"/>
    <dbReference type="OrthoDB" id="8918678at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="352"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1224"/>
            <end position="1245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="134"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="358"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1420" mass="170427" checksum="BC642D6BDD20566A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ48</accession>
    <name>A0A1J1GZ48_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">GOST seven transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00530500</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530529.1">
        <property type="nucleotide sequence ID" value="XM_028674147.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ48"/>
    <dbReference type="GeneID" id="39733838"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00530500"/>
    <dbReference type="OrthoDB" id="19932at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053937">
        <property type="entry name" value="GOST_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009637">
        <property type="entry name" value="GPR107/GPR108-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21229:SF1">
        <property type="entry name" value="GH17801P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21229">
        <property type="entry name" value="LUNG SEVEN TRANSMEMBRANE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06814">
        <property type="entry name" value="GOST_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012023501" description="GOST seven transmembrane domain-containing protein" evidence="8">
        <location>
            <begin position="17"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="294"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="326"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="367"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="399"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="428"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="474"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="509"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="GOST seven transmembrane" evidence="9">
        <location>
            <begin position="291"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF06814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG97728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="565" mass="67523" checksum="9F970ABF55F922F3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ80</accession>
    <name>A0A1J1GZ80_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Triose or hexose phosphate/phosphate translocator, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00533000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530553.1">
        <property type="nucleotide sequence ID" value="XM_028674173.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ80"/>
    <dbReference type="GeneID" id="39733863"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00533000"/>
    <dbReference type="OMA" id="NAMCAFA"/>
    <dbReference type="OrthoDB" id="18894at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="188"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="217"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="280"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="310"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="334"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="366"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="405"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="436"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="463"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="6">
        <location>
            <begin position="200"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="484" mass="55400" checksum="76219A49B84C4D82" modified="2017-02-15" version="1">MMKSLINKYNKDEEKKNNIINKKNDIDIENLTVNGISINDININDIEERIIDTNETKRKKSGNAVEYYLFDVRSYNSNSNINSENFVDLSTIKSSYLSENRKKKAKKKKSNYIKKQLKLYKKKYKILPEHNLDQDTNYEDSIKNENKNYKKYDLKEIKEDNGNNDFIQPKHKDSFDVKNDVFLSVIKFIILVSSIFSLGSFSTTITKYIIFVKKFNYTQIVTFFEFLIMYIILRIVIFFLRMKSSTDLSRRDYIKYIISISALLGLSVITGNSAYSYLEIPIISVFKSSSLILIYFLSIRFGLKEFKCSLLCSILTILMGVIMSITTLKIDSFFGIFLLVISVISSSFKWVFTNILLKSTTIKPHIVLLHIYQVAILIILLPSVFIDLTNIIKDYNSKALTIDQIYTSMILVALGAITSIFLILAEFTLISHTSSVTLSIVFIGREAIILIIGSIFFGEKINLSSSIGIGISMIGTVLYGYASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ93</accession>
    <name>A0A1J1GZ93_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Secreted ookinete protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PSOP12</name>
        <name evidence="3" type="ORF">PGAL8A_00035200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530715.1">
        <property type="nucleotide sequence ID" value="XM_028674353.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ93"/>
    <dbReference type="GeneID" id="39728876"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00035200"/>
    <dbReference type="OMA" id="KNKNTCF"/>
    <dbReference type="OrthoDB" id="391240at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041396">
        <property type="entry name" value="CyRPA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18638">
        <property type="entry name" value="CyRPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013153653" evidence="1">
        <location>
            <begin position="24"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="domain" description="Cysteine-rich protective antigen 6 bladed" evidence="2">
        <location>
            <begin position="38"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="716" mass="85238" checksum="9457244A78610690" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZV7</accession>
    <name>A0A1J1GZV7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00441500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529637.1">
        <property type="nucleotide sequence ID" value="XM_028673156.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZV7"/>
    <dbReference type="GeneID" id="39732948"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00441500"/>
    <dbReference type="OMA" id="TKRTTFE"/>
    <dbReference type="OrthoDB" id="9369505at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="65"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1135" mass="139147" checksum="AA9E5B71DF36FFCF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZX2</accession>
    <name>A0A1J1GZX2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Secy-independent transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00056300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PER33/POM33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530925.1">
        <property type="nucleotide sequence ID" value="XM_028674587.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZX2"/>
    <dbReference type="GeneID" id="39729088"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00056300"/>
    <dbReference type="OMA" id="CLSHPMV"/>
    <dbReference type="OrthoDB" id="306953at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071786">
        <property type="term" value="P:endoplasmic reticulum tubular network organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061024">
        <property type="term" value="P:membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051645">
        <property type="entry name" value="PER33/POM33_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005344">
        <property type="entry name" value="TMEM33/Pom33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12703">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12703:SF4">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03661">
        <property type="entry name" value="TMEM33_Pom33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="235"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG98128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="314" mass="38006" checksum="D9B716E12165AF46" modified="2017-02-15" version="1">MRNLTEAEEKFLNHDWVNDEKWKLYLSNLYPSPSINNIEKYKKKYFQKNIDKNLDTNINFDQIKQENQDTSNFQNFYSYNNTNYYGKLPILIFFYFIFVLCFSVFYFIILSLNLNLYKRFGTFVSFSYLLSFIGLLYLDYKTQKQNFSLLQFFSSEKGQYLSYSVILFFIKDAILIFLPIFLTLLINSYLIFKQIKLSLPPLIQKNHYVNKIVSLLDENILNTYMMRANIEIYNLLFIIICLFFKRASLLNLIIYVHFFKLKYSSADPYFHACFSKNGEMIRQYLSHPKVPRIFLNIFNKMSHYFNVYLSYRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H025</accession>
    <name>A0A1J1H025_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mediator of RNA polymerase II transcription subunit 14</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Mediator complex subunit 14</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00049500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Mediator complex subunit 14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530857.1">
        <property type="nucleotide sequence ID" value="XM_028674512.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729020"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00049500"/>
    <dbReference type="OMA" id="TICMIDQ"/>
    <dbReference type="OrthoDB" id="205099at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055122">
        <property type="entry name" value="Med14_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044285">
        <property type="entry name" value="PWP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14091">
        <property type="entry name" value="PERIODIC TRYPTOPHAN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14091:SF0">
        <property type="entry name" value="PERIODIC TRYPTOPHAN PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08638">
        <property type="entry name" value="Med14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0010">Activator</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="785"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="domain" description="Mediator complex subunit MED14 N-terminal" evidence="5">
        <location>
            <begin position="16"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="308"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1625"/>
            <end position="1676"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1830"/>
            <end position="1860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="342"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU365082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG98060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2517" mass="303860" checksum="FC6E245201A37DB5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H042</accession>
    <name>A0A1J1H042_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00054000</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530902.1">
        <property type="nucleotide sequence ID" value="XM_028674562.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H042"/>
    <dbReference type="GeneID" id="39729065"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00054000"/>
    <dbReference type="OMA" id="KYWVKYL"/>
    <dbReference type="OrthoDB" id="292964at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02257">
        <property type="entry name" value="Peptidase_C19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050185">
        <property type="entry name" value="Ub_carboxyl-term_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646:SF24">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="8">
        <location>
            <begin position="34"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG98105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="381" mass="44978" checksum="B467C581962854C0" modified="2017-02-15" version="1">MNITENNSYDILSIKNYEYYSKYYNYDNIERKLTSFNNIGNICYCNASLQLILSIKPLCIYLLKKHKKFYLNTNSKYKGDILRTLFDLIEETYSIDKNFVCTNKHINILKKIKIYNNNIVINAQNDAHEFLLMLLDFINVECNRCSKLPLNFDIKLDDKDNKEKAGDKYWYKYLFKDNSIITDLLGFQNISSITCISCGHTRYSFDFCIDLGLEFYDENLKSTTLVDLLKKNIMDKDDFCYLECNNCKLKKTSCIKKGIYRMPNLYMIIYIKRFKWIYDCKNYCNNKIKKIDTIVLLPVDGLVDFTPFAHMSNHKSLYNCKYIIESIICHSGDSYNGHYTAIVKYSDGFYLCNDDKIKKINNPYKSDNISDIYLLLLKRVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H053</accession>
    <name>A0A1J1H053_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00449500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000073">
        <property type="protein sequence ID" value="CRG96914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529717.1">
        <property type="nucleotide sequence ID" value="XM_028673245.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H053"/>
    <dbReference type="GeneID" id="39733028"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00449500"/>
    <dbReference type="OMA" id="YYPGECT"/>
    <dbReference type="OrthoDB" id="2017893at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="197" mass="23876" checksum="49EA1DC7AB331CD8" modified="2017-02-15" version="1">MYEIQLTNSKELQIELINPEKETCNIEKWDKKNFKEIIKRVFIGNYEDSKNVILLNNTSITHILIIRYSKEDYTTRINFPHKFKYYIIDLNNEFGFTSCSHFKYLLDEILFENNKNKIFIHSYFSLKYILYLLIFYIVTTLNYEIDDVILYIKKIVTDFVISNEEADKIYYFTKRHKLTYFPGEYTSYLDVTDNIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H063</accession>
    <name>A0A1J1H063_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Plasmepsin X, putative</fullName>
            <ecNumber evidence="10">3.4.23.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00051900</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.23.1" evidence="10"/>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530881.1">
        <property type="nucleotide sequence ID" value="XM_028674539.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H063"/>
    <dbReference type="GeneID" id="39729044"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00051900"/>
    <dbReference type="OMA" id="ECSACLF"/>
    <dbReference type="OrthoDB" id="771136at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000115">
        <property type="entry name" value="Lysosomal aspartic protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012204617" evidence="8">
        <location>
            <begin position="26"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="9">
        <location>
            <begin position="196"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="214"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="405"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="227"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG98084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="526" mass="60099" checksum="055BF56E7F8A03B8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H077</accession>
    <name>A0A1J1H077_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SWIB/MDM2 domain-containing protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00039800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530760.1">
        <property type="nucleotide sequence ID" value="XM_028674403.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H077"/>
    <dbReference type="GeneID" id="39728922"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00039800"/>
    <dbReference type="OMA" id="KFYAKNH"/>
    <dbReference type="OrthoDB" id="10251073at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10567">
        <property type="entry name" value="SWIB-MDM2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.245.10">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019835">
        <property type="entry name" value="SWIB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036885">
        <property type="entry name" value="SWIB_MDM2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003121">
        <property type="entry name" value="SWIB_MDM2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13844">
        <property type="entry name" value="SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02201">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00151">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47592">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51925">
        <property type="entry name" value="SWIB_MDM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DM2" evidence="1">
        <location>
            <begin position="64"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="144" mass="17265" checksum="38E44A9F5C9F9908" modified="2017-02-15" version="1">MKILKINIFNPNYLIFRNNYLPVLNKFYIRSNFTTDNRKNEEIERNESNKEIKHESVKKKKPNGLQIDCELKSPLKEFLNVNTASRIFVLKHAWKYIKDNNLQNPNMKRKIIPDEKLKQILDKDEVDILEIPKLLFRHMSSIPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H161</accession>
    <name>A0A1J1H161_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00460100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529824.1">
        <property type="nucleotide sequence ID" value="XM_028673364.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H161"/>
    <dbReference type="GeneID" id="39733134"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00460100"/>
    <dbReference type="OMA" id="DFYIYIH"/>
    <dbReference type="OrthoDB" id="375083at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005869">
        <property type="term" value="C:dynactin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061640">
        <property type="term" value="P:cytoskeleton-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009991">
        <property type="entry name" value="DCTN3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07426">
        <property type="entry name" value="Dynactin_p22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="49"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="245" mass="29261" checksum="4C443D1DE156541C" modified="2017-02-15" version="1">MKLNFEEKKAFLDNLKNRMLKIEKVIGDIKFYENNSKEKTSEENKDCYLNESNIIIDDKDNEIKSEENKNIFNELKSYLENIPFDNFNANKEELIEMIKKHKHKNSISVHLCAIKIILQQISKDFLCDIYNHYNDFYIYIHSNSIVDVYNTFEYKKNIILSHLDFMRNYSSKIKEIVKLKENINSYKISETEIYMDRLKKIENKNELLFSKISEINTSLEDVAYKYGVMMQLASLIFLKYKSNIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3E4</accession>
    <name>A0A1J1H3E4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Single-stranded DNA-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SSB</name>
        <name evidence="4" type="ORF">PGAL8A_00029900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530663.1">
        <property type="nucleotide sequence ID" value="XM_028674295.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3E4"/>
    <dbReference type="GeneID" id="39728822"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00029900"/>
    <dbReference type="OMA" id="KMNTQEF"/>
    <dbReference type="OrthoDB" id="1078367at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042645">
        <property type="term" value="C:mitochondrial nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006264">
        <property type="term" value="P:mitochondrial DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00984">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302">
        <property type="entry name" value="SINGLE-STRANDED DNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302:SF0">
        <property type="entry name" value="SINGLE-STRANDED DNA-BINDING PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012407675" evidence="3">
        <location>
            <begin position="21"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="277" mass="32499" checksum="D4B7A29FEEB3DD1C" modified="2017-02-15" version="1">MKFLFLVSIIYLNYLLKLNGYTGVVKNHSLNNILNKRIIRNKKINLIKINLQNDYNYENKKYFSSRPFINEKSLNKITLIGRVGCEPDIKILNGGDKVATFSLATNEFWRDRNTNELKSKTDWHRIVVYDQNLVELVDKYLRKGRRVYLQGSLHTRRWFGNDLNNQPKQITEVVLSYNKSDLIFLDDRRNFINRNAPQGQPIDNQNINNNDINHNINNINNSNDIIPNQSNSNGNLNKNDFSTSLDENTDDNFDMLNDNIDKNEGIYDKMNTQEFEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKR7</accession>
    <name>A0A1J1GKR7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zinc finger protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00067000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG92966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525788.1">
        <property type="nucleotide sequence ID" value="XM_028670199.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKR7"/>
    <dbReference type="GeneID" id="39729195"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00067000"/>
    <dbReference type="OrthoDB" id="376508at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012935">
        <property type="entry name" value="NuBaID_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15835">
        <property type="entry name" value="NUCLEAR-INTERACTING PARTNER OF ALK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15835:SF6">
        <property type="entry name" value="ZINC FINGER C3HC-TYPE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07967">
        <property type="entry name" value="zf-C3HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57924">
        <property type="entry name" value="Inhibitor of apoptosis (IAP) repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C3HC-type" evidence="3">
        <location>
            <begin position="45"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG92966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="591" mass="71533" checksum="D241EDE458ACC67F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKR8</accession>
    <name>A0A1J1GKR8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Mitochondrial ribosomal protein L14, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00066500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG92961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525783.1">
        <property type="nucleotide sequence ID" value="XM_028674889.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKR8"/>
    <dbReference type="GeneID" id="39729190"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00066500"/>
    <dbReference type="OMA" id="ECGHSEY"/>
    <dbReference type="OrthoDB" id="274765at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00337">
        <property type="entry name" value="Ribosomal_uL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.150.20">
        <property type="entry name" value="Ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01367">
        <property type="entry name" value="Ribosomal_uL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000218">
        <property type="entry name" value="Ribosomal_uL14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036853">
        <property type="entry name" value="Ribosomal_uL14_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761">
        <property type="entry name" value="50S/60S RIBOSOMAL PROTEIN L14/L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL14M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00238">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01374">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50193">
        <property type="entry name" value="Ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG92961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="124" mass="14083" checksum="5CC33278664EB874" modified="2017-02-15" version="1">MIKLSHIFDGLWRQSIVRCADNSGVIKACIIGIGKNKWGTGKIGDRIRVSIRDKTSECTVSEKTPKGIIVRRKKETKRKDGSYIKFDDNAFVMISKNKLKATKIKGPVAMETRHNCRNLARFIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL14</accession>
    <name>A0A1J1GL14_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00071500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525833.1">
        <property type="nucleotide sequence ID" value="XM_028674745.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL14"/>
    <dbReference type="GeneID" id="39729240"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00071500"/>
    <dbReference type="OMA" id="YFIECLY"/>
    <dbReference type="OrthoDB" id="392392at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019341">
        <property type="entry name" value="Alpha/Gamma-adaptin-bd_p34"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14659">
        <property type="entry name" value="ALPHA- AND GAMMA-ADAPTIN-BINDING PROTEIN P34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14659:SF1">
        <property type="entry name" value="ALPHA- AND GAMMA-ADAPTIN-BINDING PROTEIN P34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10199">
        <property type="entry name" value="Adaptin_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="433" mass="52029" checksum="798D3DD227633AED" modified="2017-02-15" version="1">MNDIPHIIVLSHNKGNVKSFLEHLKDKFEFLEYYENSDYYRITFDHKNINTENNYFIFKNEAKIRIINKYYSADVIISSCIVKTKKKKDHEEKESEVDIKIEKEIDVKKILYECIIFLFDNFSKEEKILINENPFRNYDDDCVEYIKDSLNGKMIKNENFDFSNLYKDIGIKIAIFPLSLQECNNEIINFFSEYFIECLYINYELETLNKNIEQKSSKIYFCDKLKEKKRNIHEDYYEEDNERLVEALHCHMWKNLEIKKKNTITHNLVDIENKIDKIKEDTDNGKDMKENRNDIDDENIKNDRIIKSKDNIKNNNNINNIGEIKYDENVKNDRIIKNKDNIKNNNNINNIGEIKYDENVKKENNVNDEKNINNNDKGEDKNTDLFLQNFNQIIEKIRLVKQENKNCSDSVRRKKAEELIFELQKYFCDIDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL22</accession>
    <name>A0A1J1GL22_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Zinc finger protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00072300</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525841.1">
        <property type="nucleotide sequence ID" value="XM_028674834.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL22"/>
    <dbReference type="GeneID" id="39729248"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00072300"/>
    <dbReference type="OMA" id="CRHAHYI"/>
    <dbReference type="OrthoDB" id="410307at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1000.10:FF:000016">
        <property type="entry name" value="Zinc finger CCCH domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045234">
        <property type="entry name" value="Unkempt-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14493:SF50">
        <property type="entry name" value="RING FINGER PROTEIN UNKEMPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14493">
        <property type="entry name" value="UNKEMPT FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="8">
        <location>
            <begin position="18"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="8">
        <location>
            <begin position="88"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="18"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="88"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="313"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="319"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="499" mass="57074" checksum="D47DDE7C2165AE17" modified="2017-02-15" version="1">MNTQSSLVIAQIPRKKQFYKTKMCPWFFSGRCDRGVDCLFAHSQDELNPIPDLSFTSLCPLAKKSGLCKNEKCSYAHSVCELRPTGDLYKTAPCTKFLRGKCNAEAHCRHAHYIEELRPLPGNVSPSQNAINLMLSSSISNPLQKINKKNSFLNDEKKNEKILKQSNSLIGNFPSQNNKFTKKFVKNASADNGSININNNINNKNYQKSSSFPNKMYPLLKNKDNNGESKLHNNINFKNYLINSDLENNNVINNFNINKLQNMCNQKKEIGRSYKSLNELRGQDSNINNNINTNKFYNLSKAKNIDTVNHYSSFSTKEPSTPMRMSSTSSKDLTSNNDENNLVDTIEHMEITAQDSALKVIEDDSEKMNSSDIKNFLNLLQMKNSNNFSKDNFLFNDNSTNNSNALYSSYKPISSSKDKLEQQLNLESHFSDHYLNNNIQNIKNKEENMNNYDSNNNLKNIYKFNNNSLISCSNFWNYPEDELSTVAPKMAQKVEIFDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL34</accession>
    <name>A0A1J1GL34_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transcription factor with AP2 domain(S), putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ApiAP2</name>
        <name evidence="9" type="ORF">PGAL8A_00078300</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525903.1">
        <property type="nucleotide sequence ID" value="XM_028670277.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729308"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00078300"/>
    <dbReference type="OrthoDB" id="372718at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00847">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="8">
        <location>
            <begin position="2652"/>
            <end position="2702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="520"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="957"/>
            <end position="1581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1587"/>
            <end position="1606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1966"/>
            <end position="1986"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2047"/>
            <end position="2140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2560"/>
            <end position="2630"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="2194"/>
            <end position="2221"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="2452"/>
            <end position="2479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="521"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="957"/>
            <end position="1215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1236"/>
            <end position="1455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1463"/>
            <end position="1581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="2051"/>
            <end position="2140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="2560"/>
            <end position="2572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="2573"/>
            <end position="2582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="2585"/>
            <end position="2608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="2609"/>
            <end position="2622"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2707" mass="315701" checksum="0CFA31FBD0EF934D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL35</accession>
    <name>A0A1J1GL35_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00074000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525858.1">
        <property type="nucleotide sequence ID" value="XM_028675023.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL35"/>
    <dbReference type="GeneID" id="39729265"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00074000"/>
    <dbReference type="OMA" id="CSIPPNE"/>
    <dbReference type="OrthoDB" id="4115at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008479">
        <property type="entry name" value="DUF760"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33598">
        <property type="entry name" value="OS02G0833400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33598:SF4">
        <property type="entry name" value="OS02G0833400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05542">
        <property type="entry name" value="DUF760"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="5"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="548"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="162"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="470"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="167"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="185"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="586" mass="70504" checksum="F6169C1E8D783E0D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLJ5</accession>
    <name>A0A1J1GLJ5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00100200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526118.1">
        <property type="nucleotide sequence ID" value="XM_028672666.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLJ5"/>
    <dbReference type="GeneID" id="39729526"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00100200"/>
    <dbReference type="OrthoDB" id="371835at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="373"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="409"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="749"/>
            <end position="779"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="786" mass="92689" checksum="9DCD7B44B8FCC4A9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLL6</accession>
    <name>A0A1J1GLL6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Gamete release protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">GAMER</name>
        <name evidence="1" type="ORF">PGAL8A_00081300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525931.1">
        <property type="nucleotide sequence ID" value="XM_028670588.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLL6"/>
    <dbReference type="GeneID" id="39729337"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00081300"/>
    <dbReference type="OrthoDB" id="390051at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="93" mass="10208" checksum="DEBE2F76D527F417" modified="2017-02-15" version="1">MEFNGFVPPHPNSPIPSGLKILPGNPKVNIPPPVYYELSPIINEDSFQMNIGGEVPSSWTINQIAHYVQFAGPDDSVFTEKAKILLRAKGYAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLM9</accession>
    <name>A0A1J1GLM9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Seipin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00098700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526103.1">
        <property type="nucleotide sequence ID" value="XM_028672499.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLM9"/>
    <dbReference type="GeneID" id="39729511"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00098700"/>
    <dbReference type="OMA" id="YMYNYPF"/>
    <dbReference type="OrthoDB" id="378375at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140042">
        <property type="term" value="P:lipid droplet formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009617">
        <property type="entry name" value="Seipin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06775">
        <property type="entry name" value="Seipin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="424"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="447"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="482" mass="59227" checksum="3E82F116728D57BF" modified="2017-02-15" version="1">MNNNNNNFNLKSETENGIVKSWVTDKDKQNSFINRRRKKERNRNYELKNNTIENENYSKNLKLFCKLKKKYLHIKKKNKILFETKKEKKKKKNPSHKTFFDLISESIINIINCMNRQYIQIKNFCINSIPNLKIKRLLYFLIIYILINIALFIFSIFLYLFLYYYVIPQNKYIYPIDFSLVKNPIEDYLKNKKNNKIYFMNKSEFHSMNEREEFYVKHLNSIKNEILDNIKNNHICCCPKNFLENSNFPLLNKNISYLNNEKLYVFDNKIENENLQNNILTGYIDFQNNPSNDSYYNEQFFYKFFLPFFKKKKNILKIKKGYKIDIFLNFTYINNDYNDKLDSFQVVTEIFNNSNNIILRKEKLYINNENYEFIKKLHLLFNTPFYFFNVNNNKTKEILLVNNYEYVTDFSKVHIYIHPPIQIYRAYVVILIYVNFIYYYIYKYPFLFFYIFVFILSSFLIFLNTIFFFFVMLYYFFIKRLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLR2</accession>
    <name>A0A1J1GLR2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Vacuolar protein sorting-associated protein 51, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">VPS51</name>
        <name evidence="5" type="ORF">PGAL8A_00099000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS51 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526106.1">
        <property type="nucleotide sequence ID" value="XM_028672533.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729514"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00099000"/>
    <dbReference type="OrthoDB" id="203678at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990745">
        <property type="term" value="C:EARP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000938">
        <property type="term" value="C:GARP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048193">
        <property type="term" value="P:Golgi vesicle transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007041">
        <property type="term" value="P:lysosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014812">
        <property type="entry name" value="Vps51"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15954">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 51 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15954:SF4">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 51 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08700">
        <property type="entry name" value="VPS51_Exo84_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="641"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="673"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1290"/>
            <end position="1312"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="705"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1293"/>
            <end position="1306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1452" mass="174441" checksum="8827F0CC20D26529" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLV8</accession>
    <name>A0A1J1GLV8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00101300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526129.1">
        <property type="nucleotide sequence ID" value="XM_028672788.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLV8"/>
    <dbReference type="GeneID" id="39729538"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00101300"/>
    <dbReference type="OMA" id="FHTISKR"/>
    <dbReference type="OrthoDB" id="390351at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013584">
        <property type="entry name" value="RAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058977">
        <property type="entry name" value="RESC8_HEAT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08373">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26172">
        <property type="entry name" value="RESC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00952">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51286">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RAP" evidence="1">
        <location>
            <begin position="472"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="563" mass="66727" checksum="F02ADEAA48388BCC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLW3</accession>
    <name>A0A1J1GLW3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Snf2-related CBP activator, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">SRCAP</name>
        <name evidence="15" type="ORF">PGAL8A_00113000</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526246.1">
        <property type="nucleotide sequence ID" value="XM_028674088.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729655"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00113000"/>
    <dbReference type="OMA" id="ELYDNNH"/>
    <dbReference type="OrthoDB" id="448448at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000812">
        <property type="term" value="C:Swr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18003">
        <property type="entry name" value="DEXQc_SRCAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000005">
        <property type="entry name" value="Photoperiod-independent early flowering 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001629">
        <property type="entry name" value="Probable ATP-dependent helicase PF08_0048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001553">
        <property type="entry name" value="Snf2-related CBP activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014012">
        <property type="entry name" value="HSA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050520">
        <property type="entry name" value="INO80/SWR1_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45685:SF1">
        <property type="entry name" value="HELICASE SRCAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45685">
        <property type="entry name" value="HELICASE SRCAP-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51204">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HSA" evidence="14">
        <location>
            <begin position="65"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="508"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="1447"/>
            <end position="1604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="289"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1731"/>
            <end position="1761"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="30"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="110"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="294"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="311"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1738"/>
            <end position="1747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1748"/>
            <end position="1761"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG93424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1761" mass="210197" checksum="B7654867A069C3C6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMM1</accession>
    <name>A0A1J1GMM1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L39, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00140200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL39 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526518.1">
        <property type="nucleotide sequence ID" value="XM_028674937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMM1"/>
    <dbReference type="GeneID" id="39729926"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00140200"/>
    <dbReference type="OMA" id="RRTKMNI"/>
    <dbReference type="OrthoDB" id="444696at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1620.10:FF:000001">
        <property type="entry name" value="60S ribosomal protein-like L39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1620.10">
        <property type="entry name" value="Ribosomal protein L39e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000077">
        <property type="entry name" value="Ribosomal_eL39"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020083">
        <property type="entry name" value="Ribosomal_eL39_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023626">
        <property type="entry name" value="Ribosomal_eL39_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19970:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19970">
        <property type="entry name" value="RIBOSOMAL PROTEIN L39E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00832">
        <property type="entry name" value="Ribosomal_L39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48662">
        <property type="entry name" value="Ribosomal protein L39e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00051">
        <property type="entry name" value="RIBOSOMAL_L39E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="51" mass="6391" checksum="C02EBC89894FEA78" modified="2017-02-15" version="1">MGSIKSFKLKQKLGKKKRQNRPVPHWYRLKKDTKIRYNTKRRHWRRTKLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMR6</accession>
    <name>A0A1J1GMR6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00126400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526379.1">
        <property type="nucleotide sequence ID" value="XM_028674783.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMR6"/>
    <dbReference type="GeneID" id="39729789"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00126400"/>
    <dbReference type="OrthoDB" id="25675at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006984">
        <property type="entry name" value="Fcf1/UTP23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12416">
        <property type="entry name" value="RRNA-PROCESSING PROTEIN UTP23 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04900">
        <property type="entry name" value="Fcf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="274"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="282"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="300"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="324"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="356" mass="42566" checksum="426CDBE75E39D931" modified="2017-02-15" version="1">MKIDKKKEFKKKLIICSSLLQVVDPLKIIIDETFINLCIIHKIPIKEELNKLINRQLIIMTTKCITANSKKLNEESAYSLKKITHYKCNHEKDYLKKSTSIFLEKINKGENSKFSPINYFENQIKITHNFDCIYNAKNEIYSNNVINENNKQVEGIITKENNELNEKDKKLNENNKITEEIINTNENVELSDSMKCILDLVKNNNEKKFFIATNNMELRYFLRKIFLVPIIYVSEGGALKIESLSIKNMKKKKNVELKKMKMLKWERDIKISEQKRNEKVRKSIKKRKKKKNRNNTNELNKNEMEVNKEKVDDKKNQIEEYMIKKQKKQNKIKKYIKKKQNRKNKRKNKKNRKKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN03</accession>
    <name>A0A1J1GN03_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PPM-type phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00144600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526562.1">
        <property type="nucleotide sequence ID" value="XM_028674985.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729970"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00144600"/>
    <dbReference type="OMA" id="DSTCFCI"/>
    <dbReference type="OrthoDB" id="380919at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1433"/>
            <end position="1458"/>
        </location>
    </feature>
    <feature type="domain" description="PPM-type phosphatase" evidence="3">
        <location>
            <begin position="935"/>
            <end position="1526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1156"/>
            <end position="1194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1156"/>
            <end position="1174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1185"/>
            <end position="1194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1536" mass="184832" checksum="2A63D312F3D14108" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP67</accession>
    <name>A0A1J1GP67_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fam-h protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00378400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000011">
        <property type="protein sequence ID" value="CRG93071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525893.1">
        <property type="nucleotide sequence ID" value="XM_028670166.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP67"/>
    <dbReference type="GeneID" id="39732314"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00378400"/>
    <dbReference type="OMA" id="TWHHEND"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022139">
        <property type="entry name" value="Fam-L/Fam-M-like_plasmodium"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12420">
        <property type="entry name" value="DUF3671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="106"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="228" mass="26571" checksum="BB8E2A7E9925E3D6" modified="2017-02-15" version="1">MRNYINSNIILNSRCISHTEENFVIEDISTLKKYRTRGKINKLFFFIKISIFTLLIWILLYCENYNYRSWNDKYNLKNKLDLGSKRSLAEGKEVIEPTNEELKVSSSNIQTNLEENNTKVEKLELKEEEKDKKEIIKIENDNVVEKKRENNKKVNSLNLIQKFKSFLRIFNIVSIVALPILSMTLSIIALSNSEKESKYVSGSNIVTSLYLVLNSILLMDLKSNSNNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP94</accession>
    <name>A0A1J1GP94_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00401700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527134.1">
        <property type="nucleotide sequence ID" value="XM_028670375.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP94"/>
    <dbReference type="GeneID" id="39732547"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00401700"/>
    <dbReference type="OMA" id="NFYFNHV"/>
    <dbReference type="OrthoDB" id="391998at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1086" mass="131243" checksum="6E5794659A748DD7" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPA6</accession>
    <name>A0A1J1GPA6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transcription factor with AP2 domain(S), putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ApiAP2</name>
        <name evidence="9" type="ORF">PGAL8A_00383800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526955.1">
        <property type="nucleotide sequence ID" value="XM_028670176.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPA6"/>
    <dbReference type="GeneID" id="39732368"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00383800"/>
    <dbReference type="OrthoDB" id="378672at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2050">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028078">
        <property type="entry name" value="ACDC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14689">
        <property type="entry name" value="PHORBOL-ESTER_DAG-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14689:SF2">
        <property type="entry name" value="PHORBOL-ESTER_DAG-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14733">
        <property type="entry name" value="ACDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00847">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2-coincident C-terminal" evidence="8">
        <location>
            <begin position="61"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="AP2/ERF" evidence="7">
        <location>
            <begin position="386"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="AP2/ERF" evidence="7">
        <location>
            <begin position="550"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="308"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="494"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="670"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="884"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1168"/>
            <end position="1214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="312"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="498"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1168"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1201"/>
            <end position="1214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF14733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1231" mass="140696" checksum="33C7D4C811D6DAB2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPB7</accession>
    <name>A0A1J1GPB7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Trs120/TRAPPC9 first Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00083100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525949.1">
        <property type="nucleotide sequence ID" value="XM_028670788.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729355"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00083100"/>
    <dbReference type="OrthoDB" id="27962at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058565">
        <property type="entry name" value="Ig_TRAPPC9_Trs120_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013935">
        <property type="entry name" value="Trs120_TRAPPC9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21512">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21512:SF5">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26254">
        <property type="entry name" value="Ig_TRAPPC9-Trs120_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="458"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="760"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2603"/>
            <end position="2625"/>
        </location>
    </feature>
    <feature type="domain" description="Trs120/TRAPPC9 first Ig-like" evidence="3">
        <location>
            <begin position="1440"/>
            <end position="1541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="593"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="606"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="685"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="699"/>
            <end position="714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF26254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2643" mass="315133" checksum="10DCFFCB39C410DE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPC6</accession>
    <name>A0A1J1GPC6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00386000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526977.1">
        <property type="nucleotide sequence ID" value="XM_028670202.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPC6"/>
    <dbReference type="GeneID" id="39732390"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00386000"/>
    <dbReference type="OrthoDB" id="371612at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1126" mass="136237" checksum="226B8731C93DF3D8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPI0</accession>
    <name>A0A1J1GPI0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00179600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527228.1">
        <property type="nucleotide sequence ID" value="XM_028670480.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPI0"/>
    <dbReference type="GeneID" id="39730323"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00179600"/>
    <dbReference type="OrthoDB" id="6362699at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="354"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="385" mass="45498" checksum="4C33093430ABD250" modified="2017-02-15" version="1">MAFLNNDGCEDSEGDFTKCFMTICEIQQKKFEASYCRIESPVVDIKKTLNNNLNDLSKNLFTYEFTPANFHSRIIILSNNDKDGILLLYEYNPNHNKYPDKTYLCRLRNINQKLTLCESINIEYFGRSLTFKSYDIFNEENKKNNMISIENPNHKIIKSKYDEFIFKEHYCHPMKTKYISYCNKRYTICKKMNNDQLHCSDANYSGNLIILDNINFPVLKRDYVYLPSGCLKENLNPVCTPYICTSRGFDKYFECKYEEISVITNIRPINNIMPKKNIMPIKDMRSINEILPCNNLIPCKHIMPHKHMLPPNNLMLMKDIRSTKNIGSNSKNPLAISLNHEDIYHENRLSNAELFAMSFMSFLVLFTFFFCLIYRIFRKKRSKYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPY5</accession>
    <name>A0A1J1GPY5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">phenylalanine--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00105700</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526173.1">
        <property type="nucleotide sequence ID" value="XM_028673276.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPY5"/>
    <dbReference type="GeneID" id="39729582"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00105700"/>
    <dbReference type="OMA" id="YECDNIR"/>
    <dbReference type="OrthoDB" id="238316at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009328">
        <property type="term" value="C:phenylalanine-tRNA ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00496">
        <property type="entry name" value="PheRS_alpha_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004529">
        <property type="entry name" value="Phe-tRNA-synth_IIc_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002319">
        <property type="entry name" value="Phenylalanyl-tRNA_Synthase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00468">
        <property type="entry name" value="pheS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003210">
        <property type="entry name" value="PRK04172.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538:SF40">
        <property type="entry name" value="PHENYLALANINE--TRNA LIGASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538">
        <property type="entry name" value="PHENYLALANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01409">
        <property type="entry name" value="tRNA-synt_2d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="12">
        <location>
            <begin position="285"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG93351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="543" mass="64389" checksum="C5469ED5470B899F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ58</accession>
    <name>A0A1J1GQ58_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Centrin-2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CEN2</name>
        <name evidence="7" type="ORF">PGAL8A_00205800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the centrin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527476.1">
        <property type="nucleotide sequence ID" value="XM_028670756.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ58"/>
    <dbReference type="GeneID" id="39730585"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00205800"/>
    <dbReference type="OMA" id="EFMRMIK"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000220">
        <property type="entry name" value="Centrin, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000232">
        <property type="entry name" value="Centrin-2, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF59">
        <property type="entry name" value="EF-HAND SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="24"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="97"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="133"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG94661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="168" mass="19424" checksum="1FF3E82F3B3D468C" modified="2017-02-15" version="1">MTENTSVRRRYEKSFTERPGFTEDEIEEIREAFNLLDTDGTGTIDPKEIKCAMQSLGLDVKNPMIFRMIADLEKDGYSTIDFEEFMEVITSKLGNKDTREGIQRIFNLFDDDKTGTISLKNLKRVAKELGETLTDEELRDMIDRADSKGEGEISFEDFYTIMTKKNFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ71</accession>
    <name>A0A1J1GQ71_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ubiquitin carboxyl-terminal hydrolase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00184400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527273.1">
        <property type="nucleotide sequence ID" value="XM_028670529.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ71"/>
    <dbReference type="GeneID" id="39730371"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00184400"/>
    <dbReference type="OMA" id="HRSHMLF"/>
    <dbReference type="OrthoDB" id="273556at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001607">
        <property type="entry name" value="Znf_UBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24007">
        <property type="entry name" value="BRCA1-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24007:SF7">
        <property type="entry name" value="BRCA1-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02148">
        <property type="entry name" value="zf-UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00290">
        <property type="entry name" value="ZnF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50271">
        <property type="entry name" value="ZF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBP-type" evidence="3">
        <location>
            <begin position="850"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="598"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1050"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1125"/>
            <end position="1152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1153" mass="139180" checksum="E009631D0BC6F151" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQE7</accession>
    <name>A0A1J1GQE7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mitotic checkpoint protein BUB3, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00203650</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527455.1">
        <property type="nucleotide sequence ID" value="XM_028670731.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQE7"/>
    <dbReference type="GeneID" id="39730563"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00203650"/>
    <dbReference type="OMA" id="WDSTLHI"/>
    <dbReference type="OrthoDB" id="10262475at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10971">
        <property type="entry name" value="MRNA EXPORT FACTOR AND BUB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="321" mass="37119" checksum="B825797973C66E81" modified="2017-02-15" version="1">MITELVSPPSDTISDASYKNNILIISSWDKSLQFYNTKENKLLKKIITNTPILSHTCINDKIIYGGLDEILYSYDFNKDIIVKLYRHKNVINNICYQKSSNFLCVSDWNKGLNIFDDRTKNGLICEISTFGLICSMDINETKLLACDSLKRTYIFDTQKGIDSFHNPYYKDNILRYQFRCIKAFPNQKGFVVSSIEGRVAWELFDNNPSVQSKNYSFRCHRIKTDESEVAYPINTIDFHPIYGAFCTGGSDGIMCVWDGYNRKRIWRTQNFKNEITKVKFNNEGDEICICVSSYLKNSNNPNDKMNSVIIRKVTDKDVKPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQK0</accession>
    <name>A0A1J1GQK0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RAP protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00212800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527546.1">
        <property type="nucleotide sequence ID" value="XM_028670833.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730655"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00212800"/>
    <dbReference type="OMA" id="TMAWAYA"/>
    <dbReference type="OrthoDB" id="2019031at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013584">
        <property type="entry name" value="RAP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08373">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00952">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51286">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RAP" evidence="1">
        <location>
            <begin position="1492"/>
            <end position="1563"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1582" mass="190986" checksum="751116D23EF21152" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQV3</accession>
    <name>A0A1J1GQV3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pre-mRNA-splicing factor ISY1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00231500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ISY1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527732.1">
        <property type="nucleotide sequence ID" value="XM_028671039.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQV3"/>
    <dbReference type="GeneID" id="39730842"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00231500"/>
    <dbReference type="OMA" id="YHWERRI"/>
    <dbReference type="OrthoDB" id="1739576at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000350">
        <property type="term" value="P:generation of catalytic spliceosome for second transesterification step"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.660:FF:000001">
        <property type="entry name" value="pre-mRNA-splicing factor ISY1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.660">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029012">
        <property type="entry name" value="Helix_hairpin_bin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009360">
        <property type="entry name" value="Isy1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037200">
        <property type="entry name" value="Isy1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13021">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR ISY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06246">
        <property type="entry name" value="Isy1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140102">
        <property type="entry name" value="ISY1 domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="206" mass="24539" checksum="94400F0EAE95317A" modified="2017-02-15" version="1">MARNVEKGKSMLNQWLKAKELNEKKNFFKIPKKVYEVDDLESAISYRKYIIKEICSKIKEIQNYSLSDQHIRELNDQINKLISIKNKWEIRIIELGGPDYQTESNTLINAHCSELKGNNNYKYFGAAKNLKGVKELLFRENEERKKLALKKKKDKRNLDKFVNIHYFGYCDDENEILLNEELKIQKKLEKNDLKILKKIRKLKNNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR89</accession>
    <name>A0A1J1GR89_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">40S ribosomal protein S28e, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00220700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527625.1">
        <property type="nucleotide sequence ID" value="XM_028670920.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR89"/>
    <dbReference type="GeneID" id="39730734"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00220700"/>
    <dbReference type="OMA" id="NTGMHGE"/>
    <dbReference type="OrthoDB" id="10258930at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04457">
        <property type="entry name" value="S1_S28E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000180">
        <property type="entry name" value="40S ribosomal protein S28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00292">
        <property type="entry name" value="Ribosomal_eS28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000289">
        <property type="entry name" value="Ribosomal_eS28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028626">
        <property type="entry name" value="Ribosomal_eS28_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10769">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10769:SF3">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN ES28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01200">
        <property type="entry name" value="Ribosomal_S28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00961">
        <property type="entry name" value="RIBOSOMAL_S28E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="67" mass="7554" checksum="AC20AB37219D55B8" modified="2017-02-15" version="1">MEKSKLAKVEKVLGRTGSRGSVIQVRAQFMGDTELSGRFLIRNVKGPVREGDILALLETEREARRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRA3</accession>
    <name>A0A1J1GRA3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ferredoxin--NADP(+) reductase</fullName>
            <ecNumber evidence="3">1.18.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00151700</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>2 reduced [2Fe-2S]-[ferredoxin] + NADP(+) + H(+) = 2 oxidized [2Fe-2S]-[ferredoxin] + NADPH</text>
            <dbReference type="Rhea" id="RHEA:20125"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.18.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferredoxin--NADP reductase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.18.1.2" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526629.1">
        <property type="nucleotide sequence ID" value="XM_028675060.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRA3"/>
    <dbReference type="GeneID" id="39730041"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00151700"/>
    <dbReference type="OMA" id="GKAWLFM"/>
    <dbReference type="OrthoDB" id="1688044at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004324">
        <property type="term" value="F:ferredoxin-NADP+ reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015701">
        <property type="entry name" value="FNR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43314">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000361">
        <property type="entry name" value="Frd-NADP+_RD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0274">FAD</keyword>
    <keyword evidence="4 9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 9 10" id="KW-0521">NADP</keyword>
    <keyword evidence="7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012136496" description="ferredoxin--NADP(+) reductase" evidence="11">
        <location>
            <begin position="19"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="12">
        <location>
            <begin position="68"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000361-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG93808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="350" mass="41327" checksum="69E67736B37FBFCA" modified="2017-02-15" version="1">MKIHFILILSFLIQGIYSDNNCVHKYAMKNKRMYNRTLFLEGTFKKKKNFRNYNNKEYNNYINLYTIKNPLKCKVVDIIKLVREKSLSEVYNIEICHNGKFKYLEGQSCGIIPYYNENDSTEDSNKNDGRKIKKQARLYSISSGDSKNLSVAIKIHKYEDIENGVKKLKYGYCSGFIKNIKKNNDIYLTGSHGSFFLPDDVVEKNKNLIFIATGTGISPYISFLKKILGYDKNNMKKKSNYNGLIHLFYGVYNEDSILYLNELEYFKKIYPYNLHIHYVFSSIKNLDGTSFHVQDEIFRKKKEFLELFNVNKSELYICGHKSIRKKIIEIIKNNEPFDEEKKKRIHVEVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRS4</accession>
    <name>A0A1J1GRS4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin-activating enzyme E1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00261400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528022.1">
        <property type="nucleotide sequence ID" value="XM_028671362.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRS4"/>
    <dbReference type="GeneID" id="39731143"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00261400"/>
    <dbReference type="OMA" id="YIDHTHD"/>
    <dbReference type="OrthoDB" id="1708823at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031510">
        <property type="term" value="C:SUMO activating enzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019948">
        <property type="term" value="F:SUMO activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF162">
        <property type="entry name" value="SUMO-ACTIVATING ENZYME SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="2">
        <location>
            <begin position="8"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="541" mass="64794" checksum="869600E2A2FD4B55" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRS7</accession>
    <name>A0A1J1GRS7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">6-cysteine protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">P48/45</name>
        <name evidence="11" type="ORF">PGAL8A_00257800</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cell surface</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRS7"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00257800"/>
    <dbReference type="OMA" id="PECFFQV"/>
    <dbReference type="OrthoDB" id="390246at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2860">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010884">
        <property type="entry name" value="6_CYS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038160">
        <property type="entry name" value="6_CYS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07422">
        <property type="entry name" value="s48_45"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00970">
        <property type="entry name" value="s48_45"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51701">
        <property type="entry name" value="6_CYS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012339654" evidence="9">
        <location>
            <begin position="26"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="425"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="10">
        <location>
            <begin position="43"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="10">
        <location>
            <begin position="292"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG95173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="445" mass="50938" checksum="C63DBC97F7144221" modified="2017-02-15" version="1">MLYYIKKFNTVFLFYVLIIIKTIKGDEEYISPNDLGNKISGFLGYKCNFSTKGVHNLEPDILEYRSVFCSVNSYFIYDKIRLMIPKNDKTSKFKILPGSCFQKVYVDFDKRVETDISDLGLVEYEVNEDDSSPDYTEKTITISPFNNTDVEFFCFCDNTGKVVSDVEGRSALVYVHVLKYPHDIISINLTNDSFPYLKNPKSKEDFEHNSLEVELKSGELLVLACELIDKECFQKPKYNDLYKSNKIIYHKKFAIFKAPSYTKAGDMDAACTCKADSIVYSIIAKPKEEKKMIHGCDFSTDDASEQFSNSVNLKKAEDNTPVNCEIDLKEKTYNHLIGLKCPGEIIPDCFFQVYQQEKEQLEPSKIVYLDAHLNVGHIEYFEDSKVEDKVKIFGIVGSVPKDTTFVCLCKNGKKTGYMTVKIASGYYGFLAKIFIFLIVIILLYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS22</accession>
    <name>A0A1J1GS22_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00380800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526925.1">
        <property type="nucleotide sequence ID" value="XM_028670143.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS22"/>
    <dbReference type="GeneID" id="39732338"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00380800"/>
    <dbReference type="OMA" id="NFSCLFY"/>
    <dbReference type="OrthoDB" id="377446at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="128"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="827"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="860"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="903"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="946"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="972"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="996"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="375"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="445"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="653"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="591"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="380"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="390"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="450"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="653"/>
            <end position="666"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1055" mass="126838" checksum="AEB18C56D02414A5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSB2</accession>
    <name>A0A1J1GSB2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Male gamete fusion factor HAP2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">HAP2</name>
        <name evidence="14" type="ORF">PGAL8A_00390400</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HAP2/GCS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527021.1">
        <property type="nucleotide sequence ID" value="XM_028670250.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSB2"/>
    <dbReference type="GeneID" id="39732434"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00390400"/>
    <dbReference type="OMA" id="EVYEIRP"/>
    <dbReference type="OrthoDB" id="365272at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007338">
        <property type="term" value="P:single fertilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040326">
        <property type="entry name" value="HAP2/GCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018928">
        <property type="entry name" value="HAP2/GCS1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31764:SF0">
        <property type="entry name" value="GENERATIVE CELL SPECIFIC-1_HAP2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31764">
        <property type="entry name" value="PROTEIN HAPLESS 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10699">
        <property type="entry name" value="HAP2-GCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0278">Fertilization</keyword>
    <keyword evidence="7" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="672"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="domain" description="Generative cell specific-1/HAP2" evidence="13">
        <location>
            <begin position="51"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="732"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="810"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="740"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="759"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="810"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="822"/>
            <end position="843"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF10699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG94200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="853" mass="99283" checksum="0A6792EA00034C6B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSE5</accession>
    <name>A0A1J1GSE5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00167900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526792.1">
        <property type="nucleotide sequence ID" value="XM_028669996.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSE5"/>
    <dbReference type="GeneID" id="39730205"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00167900"/>
    <dbReference type="OMA" id="YIWPSNF"/>
    <dbReference type="OrthoDB" id="289113at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1720.10">
        <property type="entry name" value="endopeptidase domain like (from Nostoc punctiforme)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024453">
        <property type="entry name" value="Peptidase_C92"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47112">
        <property type="entry name" value="PX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47112:SF1">
        <property type="entry name" value="PX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05708">
        <property type="entry name" value="Peptidase_C92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="1">
        <location>
            <begin position="40"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="363" mass="42923" checksum="2614671978B93A97" modified="2017-02-15" version="1">MKKSLKENCIDNIENDIHKEEYLDFSDDFIFCSNYKKFSPYYKEGYLEKKCSNSWCGYKKRWFLLKNKKLYYFKNKESFRPSGVLDLDLINMNINYENGLNRKKRLDDCFIYCIESRKNKDESFLILNPKNTYINFYLKGEDKEIIEWYNLLNSSIDNKKILNQPKFIFSENNFWKIDRISVEVFEAIADTGDIILFRSNVISGKLQRILTGGDYDHIGMILRNDKNDLFLLEAISNMGIILTPWTLFVKNKWNEAYSRISLRRLTWNNSEENLQKLLDFLKNTVGKKYNLKIVNFLVSKNDDNNGYFCSELIGECWKIMGVIPLNTSCSNILPSNFSEKFEEKIKLHSGCQLNNELCIDFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSM9</accession>
    <name>A0A1J1GSM9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00411200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000044">
        <property type="protein sequence ID" value="CRG95533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528342.1">
        <property type="nucleotide sequence ID" value="XM_028671717.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732642"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00411200"/>
    <dbReference type="OrthoDB" id="348930at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="281"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="431"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="574"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="701"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="874"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1134"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="289"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="324"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="375"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="390"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="431"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="503"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="533"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="574"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="701"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="751"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="878"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1656"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1656" mass="190385" checksum="D53DCFA01AAC034F" modified="2017-02-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSQ2</accession>
    <name>A0A1J1GSQ2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00005300</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UQCRQ/QCR8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528099.1">
        <property type="nucleotide sequence ID" value="XM_028671448.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSQ2"/>
    <dbReference type="GeneID" id="39728575"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00005300"/>
    <dbReference type="OMA" id="LWKMFRD"/>
    <dbReference type="OrthoDB" id="359909at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045275">
        <property type="term" value="C:respiratory chain complex III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.210">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036642">
        <property type="entry name" value="Cyt_bc1_su8_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81508">
        <property type="entry name" value="Ubiquinone-binding protein QP-C of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG95288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="136" mass="16871" checksum="B853962CC235656D" modified="2017-02-15" version="1">MAITILKEQNFYNIKNKIIRFKKNYICYQRNIIRDNVVKKATPKFEQKPLGKYPIPPEAEMTWKNRHTAYGGYIQQTISPFQQKIMYPFWHMAMARWWAKFSSYLWWWIWPFALTNLILYKMFYDAKKQVKNKHWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSU2</accession>
    <name>A0A1J1GSU2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Secreted ookinete adhesive protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SOAP</name>
        <name evidence="3" type="ORF">PGAL8A_00276100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528372.1">
        <property type="nucleotide sequence ID" value="XM_028671750.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSU2"/>
    <dbReference type="GeneID" id="39731293"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00276100"/>
    <dbReference type="OrthoDB" id="369750at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013289349" evidence="2">
        <location>
            <begin position="21"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="134"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="204" mass="21620" checksum="97D339266264657F" modified="2017-02-15" version="1">MKKIFIIFVSLFCAFIYGKGVRNISRKSSVAHPHNQHKVKNVSALEIFSREKTEKDCIKCLPENFCECECNCKNKTGFSMKYRNASLGSNSKRKSMNVNKKISRSRKCNDLPIEDNSGSGAGTEGSGTEGSGTEGSETEGSGTEGSETEGSETEGSGTEGSGTEGSGTEGSGTEGSENGATECYSSCHTETGVQTEECNCSCSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSU8</accession>
    <name>A0A1J1GSU8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">GTP-binding protein EngA, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00012700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528169.1">
        <property type="nucleotide sequence ID" value="XM_028671525.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSU8"/>
    <dbReference type="GeneID" id="39728649"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00012700"/>
    <dbReference type="OMA" id="CANREKC"/>
    <dbReference type="OrthoDB" id="8954335at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032859">
        <property type="entry name" value="KH_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43834">
        <property type="entry name" value="GTPASE DER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43834:SF2">
        <property type="entry name" value="GTPASE DER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14714">
        <property type="entry name" value="KH_dom-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G" evidence="4">
        <location>
            <begin position="15"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="G" evidence="4">
        <location>
            <begin position="525"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="domain" description="GTPase Der C-terminal KH-domain-like" evidence="5">
        <location>
            <begin position="707"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="213"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="801" mass="96020" checksum="E886E0CCA15D559A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSW1</accession>
    <name>A0A1J1GSW1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00276700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528378.1">
        <property type="nucleotide sequence ID" value="XM_028671758.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSW1"/>
    <dbReference type="GeneID" id="39731300"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00276700"/>
    <dbReference type="OrthoDB" id="392484at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="60"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="298" mass="35170" checksum="C928D5E398C4D9D9" modified="2017-02-15" version="1">MYKNKVLFVFLFSFFYFFVLFYVNGKGENKNILSSMKNENNKNTNLDHISNLIDMDKIKQLIAENKIEEANNLLKEMQQALKKEETDEHKDNNEIDKYEEVNNKMFDNLISASDLHEMMKFYMYLQNLLNSKSESSEKKMVKTFLRKTIQKMKDNENNKEKKSIDDIIKDTEGHKEMLEKLADVMKIDREKLKDEEVKNKLNQILIGMLKFIEYTNNNELVNALMDEIEIKEVKAEDGASKPKIQVNINNSKTHLEMLQKASNFMGLEINQEDLQKLTSNNKWYENFLNNILNSSDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSW5</accession>
    <name>A0A1J1GSW5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ATP-dependent Clp protease, putative</fullName>
            <ecNumber evidence="9">3.4.21.92</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ClpC</name>
        <name evidence="9" type="ORF">PGAL8A_00278500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.92" evidence="9"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528396.1">
        <property type="nucleotide sequence ID" value="XM_028671778.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSW5"/>
    <dbReference type="GeneID" id="39731318"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00278500"/>
    <dbReference type="OrthoDB" id="47330at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19499">
        <property type="entry name" value="RecA-like_ClpB_Hsp104-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="entry name" value="Clp, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050130">
        <property type="entry name" value="ClpA_ClpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638:SF18">
        <property type="entry name" value="HEAT SHOCK PROTEIN 104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="Double Clp-N motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009618941" evidence="6">
        <location>
            <begin position="19"/>
            <end position="1217"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="7">
        <location>
            <begin position="512"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="7">
        <location>
            <begin position="878"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="domain" description="Clp ATPase C-terminal" evidence="8">
        <location>
            <begin position="1112"/>
            <end position="1206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="216"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="259"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1033"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="740"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="259"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="310"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG95588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1217" mass="141283" checksum="45AF11E2EB51AB07" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSY8</accession>
    <name>A0A1J1GSY8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MORN repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00386700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526984.1">
        <property type="nucleotide sequence ID" value="XM_028670209.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSY8"/>
    <dbReference type="GeneID" id="39732397"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00386700"/>
    <dbReference type="OMA" id="YKKCKSI"/>
    <dbReference type="OrthoDB" id="387430at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43215">
        <property type="entry name" value="RADIAL SPOKE HEAD 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43215:SF14">
        <property type="entry name" value="RADIAL SPOKE HEAD 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="91"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="106"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="124"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="160"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="280"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="304"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="489" mass="58025" checksum="F33709583C5E7A3D" modified="2017-02-15" version="1">MSLKEHKNNKIKLLKYNGESINSLENYSGIGTVIFYPHKNMKKREKYYGNLLQGRKHGYGEYKYYNGDIYQGFYEHDKKNGIGTYFYNNTSKEKKEKKKSKKHEDIEENEDESEEDKDNKKENSDEEKDYSENENDSKDDDEDENESESEDKDKDKDEKGEDEESESNEDEDEKSEGKNDEDDDDDEEGEIDEDEDEDDDEDEDDEDDEDDDEDDEDDEDDDDDEDDEEDEEDDDDKDEEDDDDKDDEDDKDDKDDEDDKDDEDDEDENEGNKSNGDNDGDSKGMKDNEKTEDEYMEIYNNDDENYKDSDENENQKNKEYYKKKKISKKLLKLMKNLNETKGKKHIINPFKEKRNYYYGNYFNGLKHNNGMMLYANEDIYVGNWKFGKKNGWGKYIYKKCKSILEGYWVDGYISYGKWILPNGTYFVGNFKENKPIGDGVWVFNDKTQLNVFYDQIELKSKKKKNKKGEKCSNIVLKYKPLYITSTRET</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT05</accession>
    <name>A0A1J1GT05_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00388300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527000.1">
        <property type="nucleotide sequence ID" value="XM_028670227.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT05"/>
    <dbReference type="GeneID" id="39732413"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00388300"/>
    <dbReference type="OMA" id="NFQRVLY"/>
    <dbReference type="OrthoDB" id="419317at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="281"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="386" mass="46842" checksum="2CF2E9D038756281" modified="2017-02-15" version="1">MSYINNFQRVLYASRFMRVFGKFKRAQLREKPQRKIGPFCNPVKRLVRLKEKEKLFCEIGLPRIIPRAKIVTKEKILEAIKPPNVSKEVLDRRLEFLLSNESVYQQMYNKMYNGITPYQCELYMWERQMRDLRKIYRAQYLHKLSEVTNEERVKQLKLLLQTKEDKRKRRENIRNRILEDKKRKAILKDRLNLEKKVTQSILFKRQSNRKKQNIYWLMKLQKKSEYSDSDDLKKKIEENIDENNLFNRNISVSSLYKDLGYEVKEEKNDNMKIFKVDKIYRELLEESFEFLDEDEEQFEENLQENDENITHKQRAHILYSSFTNEEKIKLLDDKIAILSKKIEEKSFAKGIENNNIMFYIQLKDKLEAAKQAFLEKNYLKNINKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT39</accession>
    <name>A0A1J1GT39_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Early transcribed membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ETRAMP</name>
        <name evidence="2" type="ORF">PGAL8A_00265700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000034">
        <property type="protein sequence ID" value="CRG95454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528265.1">
        <property type="nucleotide sequence ID" value="XM_028671631.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT39"/>
    <dbReference type="GeneID" id="39731186"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00265700"/>
    <dbReference type="OrthoDB" id="369758at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1330">
        <property type="entry name" value="Plasmodium falciparum UIS3 membrane protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006389">
        <property type="entry name" value="Early_transc_mb_plasmodium"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021626">
        <property type="entry name" value="PfUIS3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038403">
        <property type="entry name" value="PfUIS3_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01495">
        <property type="entry name" value="ETRAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09716">
        <property type="entry name" value="ETRAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11567">
        <property type="entry name" value="PfUIS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="231" mass="26789" checksum="B6ED92B2BA743740" modified="2017-02-15" version="1">MNISKIFYFFNFLFIVNLILPCLSQNKISNANNMDSLEHVDAFLEKRKKRKRNIILCSLILTGLITSAAIACGVGWYIKKNKDDIFEYPEYPEFSEFPDNFFTQPDGEMPGTSQSDITTESAVSNINKIDLNKPLIENNKQEDISFKKFNAFVDSSRLAIKNLFNSLNDLEKSVFIVDKDYMRKVIQNLESNRNVELSRKQEDKAVLEMEYYLQKLYANYLSEAIHTKGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT46</accession>
    <name>A0A1J1GT46_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fam-f protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00186900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000025">
        <property type="protein sequence ID" value="CRG94474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527293.1">
        <property type="nucleotide sequence ID" value="XM_028670552.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT46"/>
    <dbReference type="GeneID" id="39730396"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00186900"/>
    <dbReference type="OrthoDB" id="1490254at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="584" mass="69829" checksum="4A424A8D3277A757" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT98</accession>
    <name>A0A1J1GT98_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00397900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527096.1">
        <property type="nucleotide sequence ID" value="XM_028670334.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT98"/>
    <dbReference type="GeneID" id="39732509"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00397900"/>
    <dbReference type="OMA" id="MINKDHI"/>
    <dbReference type="OrthoDB" id="2152435at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039902">
        <property type="entry name" value="CCDC148/CCDC112"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21549:SF0">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21549">
        <property type="entry name" value="MUTATED IN BLADDER CANCER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="134"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="469"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="595" mass="71690" checksum="D0E3A7F0603835A2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTI4</accession>
    <name>A0A1J1GTI4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">WD repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00280600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528417.1">
        <property type="nucleotide sequence ID" value="XM_028671801.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTI4"/>
    <dbReference type="GeneID" id="39731339"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00280600"/>
    <dbReference type="OrthoDB" id="371245at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043527">
        <property type="term" value="C:tRNA methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036265">
        <property type="term" value="P:RNA (guanine-N7)-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028884">
        <property type="entry name" value="Trm82"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16288:SF0">
        <property type="entry name" value="TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT WDR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16288">
        <property type="entry name" value="WD40 REPEAT PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="67"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="504" mass="60030" checksum="38A8AEF612FC71F1" modified="2017-02-15" version="1">MKKRQKINSLNTSLGSKSTNLSDHEKKYIYPCIPNSPIIFNKNQIIYGYGNTLLVFCKKENKFIKKIEEHKNAIRSLDISENKKYFLTTGDDKIIIIYDENWSIIQKIIHKKKIVKAYFLKYIEKETNKFEILLIDKYGDIYIYDLNNLRNKSNLINEKNKNEIIDNDFIMKKDEDIVKLTYLYDSLSEVNEKDEDLFFMKDFEHIYNENLENCMLDNNGDIKSDIETTNTENNDVLNLKNVKKMNDIKEKLEKHYFECFQNKNLLYPTLTCNSTVISLYYDEKFLIIGDRDEKIRIIKNKRLNKIYNFYLNHKLFITSVLLINEKTFCSSAADGYIYLWNIKTKEVIDYIYLDFNFLSKFIDIKSLFNNSINLDKYKFIVNILNFNENTYSIFATIENLKGIMIIPLIKNENSAFINFNKEKIFFFTLDYNILSFMLLNINSQNFIVFVDRNKGYLHQIKLGDDNNLNEEVATFDHSFFEDKNELDIGLINYWKHTTIEDIEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTN1</accession>
    <name>A0A1J1GTN1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Pre-mRNA-splicing factor 38B, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PRP38B</name>
        <name evidence="9" type="ORF">PGAL8A_00279200</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PRP38 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528403.1">
        <property type="nucleotide sequence ID" value="XM_028671785.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTN1"/>
    <dbReference type="GeneID" id="39731325"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00279200"/>
    <dbReference type="OrthoDB" id="3881at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005037">
        <property type="entry name" value="PRP38"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23142">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR 38A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03371">
        <property type="entry name" value="PRP38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="429"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="604"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="429"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="439"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="507"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG95595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="653" mass="77413" checksum="A418FC487706D497" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTN2</accession>
    <name>A0A1J1GTN2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00308000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528676.1">
        <property type="nucleotide sequence ID" value="XM_028672089.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTN2"/>
    <dbReference type="GeneID" id="39731613"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00308000"/>
    <dbReference type="OMA" id="GVLWPKF"/>
    <dbReference type="OrthoDB" id="269151at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023179">
        <property type="entry name" value="GTP-bd_ortho_bundle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45782">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45782:SF4">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G" evidence="3">
        <location>
            <begin position="188"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="399" mass="46234" checksum="E0B7330EDB5FAF01" modified="2017-02-15" version="1">MSSNISIWKKELGPNLSDIFLKKDLDDVINNDEKKKYIYLNTIDGGIKNSQDKKEKYSDFICRDKFIYDVNITCFPNYMHKSSLNIKKKFDICDLIIEVRDARLPFTSTNDFIIDSLKQYKNKKRIVILNKVDLISKKVALKAQNLIEEKTNSICLLTSSKYNKNISKIRDICKEIKPKFKSFGVFAMLIGLPNVGKSSIINSFKDVTYNMGKYGYKNNKIAFEVNRKKVKTNIIAGTTKLVDTYKVSNNPLIYFIDTPGIFLPKMNDKEISLKLSAIGNILNYKYDHMYVGDYILFTLNKYKYYNYVKVIGLDSPTNDIRFVSNVISTKLNLCRNYKYLDINGGCRFFIDLFRLGLFGQICLDLVPNKKDFVTYFDFKSEEPLTVNSQKHPLPFRGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTU2</accession>
    <name>A0A1J1GTU2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Dynactin subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PGAL8A_00212300</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="13">Subunit of dynactin, a multiprotein complex part of a tripartite complex with dynein and a adapter, such as BICDL1, BICD2 or HOOK3. The dynactin complex is built around ACTR1A/ACTB filament and consists of an actin-related filament composed of a shoulder domain, a pointed end and a barbed end. Its length is defined by its flexible shoulder domain. The soulder is composed of 2 DCTN1 subunits, 4 DCTN2 and 2 DCTN3. The 4 DCNT2 (via N-terminus) bind the ACTR1A filament and act as molecular rulers to determine the length. The pointed end is important for binding dynein-dynactin cargo adapters. Consists of 4 subunits: ACTR10, DCNT4, DCTN5 and DCTN6. The barbed end is composed of a CAPZA1:CAPZB heterodimers, which binds ACTR1A/ACTB filament and dynactin and stabilizes dynactin. Interacts with ATP7B, but not ATP7A, in a copper-dependent manner. Interacts with ANK2; this interaction is required for localization at costameres. Interacts with N4BP2L1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Stress fiber</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Myofibril</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the dynactin subunit 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527541.1">
        <property type="nucleotide sequence ID" value="XM_028670827.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTU2"/>
    <dbReference type="GeneID" id="39730650"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00212300"/>
    <dbReference type="OMA" id="CTQIYTK"/>
    <dbReference type="OrthoDB" id="283815at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005813">
        <property type="term" value="C:centrosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005869">
        <property type="term" value="C:dynactin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001725">
        <property type="term" value="C:stress fiber"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008603">
        <property type="entry name" value="DCTN4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13034">
        <property type="entry name" value="DYNACTIN P62 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13034:SF2">
        <property type="entry name" value="DYNACTIN SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05502">
        <property type="entry name" value="Dynactin_p62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0007">Acetylation</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0832">Ubl conjugation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00093507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG94726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="696" mass="83067" checksum="36F0E7495C4610B8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTX8</accession>
    <name>A0A1J1GTX8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Signal peptide peptidase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00216300</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase A22B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527581.1">
        <property type="nucleotide sequence ID" value="XM_028670872.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTX8"/>
    <dbReference type="GeneID" id="39730690"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00216300"/>
    <dbReference type="OMA" id="FLYDIWW"/>
    <dbReference type="OrthoDB" id="29661at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098554">
        <property type="term" value="C:cytoplasmic side of endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098553">
        <property type="term" value="C:lumenal side of endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042500">
        <property type="term" value="F:aspartic endopeptidase activity, intramembrane cleaving"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033619">
        <property type="term" value="P:membrane protein proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007369">
        <property type="entry name" value="Peptidase_A22B_SPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006639">
        <property type="entry name" value="Preselin/SPP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12174:SF23">
        <property type="entry name" value="MINOR HISTOCOMPATIBILITY ANTIGEN H13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12174">
        <property type="entry name" value="SIGNAL PEPTIDE PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04258">
        <property type="entry name" value="Peptidase_A22B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00730">
        <property type="entry name" value="PSN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="21"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="164"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="193"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="254"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="307"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="336"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="374"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="374"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG94766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="407" mass="47090" checksum="6C41918481F747D8" modified="2017-02-15" version="1">MGKINKMRNVKMSNSIIYHSCYIIIVLTIIMSRFIVIPLIAQMFLYTFITIYIGSHDSLKQLEIDDRKKNADNITAYDAIMFPIIGSGALLTLYFAYKFLDPYYVNLLLTVYLTLAGVFSLQGVFSNILEPIFPNFFKRDEYVKTINLPSFIYKEPVIFNTNKGEILCFILCFLIGLRWIFYKDFITHNVLAVSFCFQAISLVILSNFLIGLLLLSGLFVYDIFWVFGNDVMVTVAKSFEAPVKLLFPVSRDPLHYSMLGLGDIIIPGIVISLCLRFDYYLYKNKIHNGNIKKMFNDINIHESFKKYYFYSIIILYQIGLIVTYCMLFYFEHPQPALLYLVPACIIAILGCSLCKGEFKLMIKYQEITDKTTKTKVDEKNKQNSDKEEIIKNEEPVASNTKKRVTNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTZ0</accession>
    <name>A0A1J1GTZ0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutathione S-transferase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00291100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528515.1">
        <property type="nucleotide sequence ID" value="XM_028671909.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTZ0"/>
    <dbReference type="GeneID" id="39731444"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00291100"/>
    <dbReference type="OMA" id="LDLMMMI"/>
    <dbReference type="OrthoDB" id="422574at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03192">
        <property type="entry name" value="GST_C_Sigma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03039">
        <property type="entry name" value="GST_N_Sigma_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571:SF150">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01205">
        <property type="entry name" value="AMPS.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00363">
        <property type="entry name" value="AMPS_(cytGST):_Alpha-__Mu-__Pi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="3"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="89"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="205" mass="24170" checksum="9F9302365B90EB01" modified="2017-02-15" version="1">MGENIVLYYFDARGKAELIRLIFAYLGIKYTDKRFGENGDAFVEFKDFKKEKEIPFNQVPILEINNLILAQSQAIVRYLSKKYKISGNNELDEFYADMIFCGVQDIHYKFNNTNLFKQNETTFLNEELPKWSGYFENLLKKNNSTYFVGDNLTYADLAVFNLYDDIESKYPNSLKNFPLLKTHNEFISNIPNIKNYINNRKESVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUJ3</accession>
    <name>A0A1J1GUJ3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine esterase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00342700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529014.1">
        <property type="nucleotide sequence ID" value="XM_028672464.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731957"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00342700"/>
    <dbReference type="OMA" id="HIGVHEN"/>
    <dbReference type="OrthoDB" id="273452at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007751">
        <property type="entry name" value="DUF676_lipase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044294">
        <property type="entry name" value="Lipase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12482:SF62">
        <property type="entry name" value="LIPASE ROG1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12482">
        <property type="entry name" value="LIPASE ROG1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05057">
        <property type="entry name" value="DUF676"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF676" evidence="3">
        <location>
            <begin position="568"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1131"/>
            <end position="1153"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="74"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1131"/>
            <end position="1151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1435" mass="170723" checksum="DC8F71F7E34D18EE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUK8</accession>
    <name>A0A1J1GUK8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00338300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528970.1">
        <property type="nucleotide sequence ID" value="XM_028672415.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUK8"/>
    <dbReference type="GeneID" id="39731913"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00338300"/>
    <dbReference type="OMA" id="LYINYDM"/>
    <dbReference type="OrthoDB" id="370356at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="187" mass="23095" checksum="34D976C1C980C3CF" modified="2017-02-15" version="1">MKKRKNNSKVQVLERSFRRKGKIKTIYEKHDDLEFINIIDKNINYIWNYINNIDDIVNDDEFLKEEIKEKIEKKKNVKQIDDYDEIIYYNKNLSNQINIQKIRKALYHFNIKVNIDDIIKMFLYYTNNDYFKKIIKNDIYSNDYIEKKKDDKKFNSLNINNLYINYEMFKYIFLHIDLNIESNGKIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUM8</accession>
    <name>A0A1J1GUM8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">dipeptidyl-peptidase I</fullName>
            <ecNumber evidence="4">3.4.14.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00343300</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, except when Xaa is Arg or Lys, or Yaa or Zaa is Pro.</text>
            <dbReference type="EC" id="3.4.14.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>chloride</name>
            <dbReference type="ChEBI" id="CHEBI:17996"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase C1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.14.1" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529020.1">
        <property type="nucleotide sequence ID" value="XM_028672471.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUM8"/>
    <dbReference type="GeneID" id="39731963"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00343300"/>
    <dbReference type="OMA" id="CYIASQM"/>
    <dbReference type="OrthoDB" id="640249at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.80">
        <property type="entry name" value="Cathepsin C, exclusion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014882">
        <property type="entry name" value="CathepsinC_exc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036496">
        <property type="entry name" value="CathepsinC_exc_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025661">
        <property type="entry name" value="Pept_asp_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025660">
        <property type="entry name" value="Pept_his_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013128">
        <property type="entry name" value="Peptidase_C1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000668">
        <property type="entry name" value="Peptidase_C1A_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12411">
        <property type="entry name" value="CYSTEINE PROTEASE FAMILY C1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08773">
        <property type="entry name" value="CathepsinC_exc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00112">
        <property type="entry name" value="Peptidase_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00645">
        <property type="entry name" value="Pept_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75001">
        <property type="entry name" value="Dipeptidyl peptidase I (cathepsin C), exclusion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00640">
        <property type="entry name" value="THIOL_PROTEASE_ASN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00639">
        <property type="entry name" value="THIOL_PROTEASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8" id="KW-0868">Chloride</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0865">Zymogen</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C1A papain C-terminal" evidence="11">
        <location>
            <begin position="389"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG96215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="706" mass="82388" checksum="2C71591A71C145D7" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV61</accession>
    <name>A0A1J1GV61_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00360500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529186.1">
        <property type="nucleotide sequence ID" value="XM_028672656.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV61"/>
    <dbReference type="GeneID" id="39732135"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00360500"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="29" mass="3091" checksum="CE898F94B2BDCA80" modified="2017-02-15" version="1">MCCCICGLLFLALIAIIVVLILKGIIKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVE1</accession>
    <name>A0A1J1GVE1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00347800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529065.1">
        <property type="nucleotide sequence ID" value="XM_028672520.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVE1"/>
    <dbReference type="GeneID" id="39732008"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00347800"/>
    <dbReference type="OMA" id="MFTFPCF"/>
    <dbReference type="OrthoDB" id="361325at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="154" mass="19167" checksum="CBE353C06D67A7A4" modified="2017-02-15" version="1">MFTFPCFRDKKWMKQNGTNMKYPDEFFNVQFRPDFLRYYEHTINFEEKVKHVIDQIKSALFRQAIYKIQNIEVMAMNECKEDRVLEKIKKIKGYENFKISNSKILCDEIWTIKRCNKKISYWVRYYEQDKNGYSLSIMPTQIKNIFYFFKYYYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVI0</accession>
    <name>A0A1J1GVI0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Eukaryotic translation initiation factor 6</fullName>
            <shortName evidence="6">eIF-6</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">EIF6</name>
        <name evidence="7" type="ORF">PGAL8A_00245000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer. Associates with the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleolus</location>
        </subcellularLocation>
        <text evidence="6">Shuttles between cytoplasm and nucleus/nucleolus.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the eIF-6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVI0"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00245000"/>
    <dbReference type="OMA" id="WCAFCGM"/>
    <dbReference type="OrthoDB" id="4155914at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042256">
        <property type="term" value="P:cytosolic ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00527">
        <property type="entry name" value="IF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.75.10.10:FF:000006">
        <property type="entry name" value="Eukaryotic translation initiation factor 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.75.10.10">
        <property type="entry name" value="L-arginine/glycine Amidinotransferase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00032">
        <property type="entry name" value="eIF_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002769">
        <property type="entry name" value="eIF6"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00323">
        <property type="entry name" value="eIF-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10784">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01912">
        <property type="entry name" value="eIF-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006413">
        <property type="entry name" value="IF-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00654">
        <property type="entry name" value="eIF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55909">
        <property type="entry name" value="Pentein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0690">Ribosome biogenesis</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="247" mass="27227" checksum="E48ED2C638E9B9A1" modified="2017-02-15" version="1">MAIRVQFENSNEVGVFSRLTNSYALIALGSSENFSSVFESELSQHIPLVYTTIGGTKVIGRVCVGNRKGLLVSSICTDQELLHLRNSLPENVKIKRIEERLSALGNCITANDYVGLIHTDIDRETEEIIQDVLDIEVFRTSIAGNLLVGTYSYFTNNGGLLHAMTSSQEIEELSELLQIPLITGTINRGSDLIGSGLVANDWSAFCGMDTTAIELSIIEKVFKLNNINDNNITNNFKYKSSIIKTMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVI4</accession>
    <name>A0A1J1GVI4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00006400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528109.1">
        <property type="nucleotide sequence ID" value="XM_028671459.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVI4"/>
    <dbReference type="GeneID" id="39728586"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00006400"/>
    <dbReference type="OMA" id="DLGQWVG"/>
    <dbReference type="OrthoDB" id="10249311at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000530">
        <property type="entry name" value="Ribosomal_eS12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047860">
        <property type="entry name" value="Ribosomal_eS12_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11843">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00972">
        <property type="entry name" value="RIBSOMALS12E"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01189">
        <property type="entry name" value="RIBOSOMAL_S12E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="5">
        <location>
            <begin position="24"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="141" mass="15419" checksum="603B4CFD7D87FF99" modified="2017-02-15" version="1">MTDVESVDNNVVVEEKAVLDNTTAIQKVIKNAHVHDGLKVGIREVIKAIESKEAKVCFLSSVCSEPAYKKLITALCTEKNIPLFLVQNDSKDLGHWAGLYKLDKEGNARKIIGASSVAIVDFGEDSAEREFLMSQKQTAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVI6</accession>
    <name>A0A1J1GVI6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">coproporphyrinogen oxidase</fullName>
            <ecNumber evidence="4">1.3.3.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CPO</name>
        <name evidence="7" type="ORF">PGAL8A_00369900</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the aerobic coproporphyrinogen-III oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.3" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529279.1">
        <property type="nucleotide sequence ID" value="XM_028672759.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVI6"/>
    <dbReference type="GeneID" id="39732229"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00369900"/>
    <dbReference type="OMA" id="CVNQYNK"/>
    <dbReference type="OrthoDB" id="15318at2759"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00322"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004109">
        <property type="term" value="F:coproporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1500.10">
        <property type="entry name" value="Coproporphyrinogen III oxidase, aerobic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001260">
        <property type="entry name" value="Coprogen_oxidase_aer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036406">
        <property type="entry name" value="Coprogen_oxidase_aer_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10755">
        <property type="entry name" value="COPROPORPHYRINOGEN III OXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10755:SF0">
        <property type="entry name" value="OXYGEN-DEPENDENT COPROPORPHYRINOGEN-III OXIDASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01218">
        <property type="entry name" value="Coprogen_oxidas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102886">
        <property type="entry name" value="Coproporphyrinogen III oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="444" mass="53127" checksum="93DD74B92FB03BEE" modified="2017-02-15" version="1">MKDEISPNEYFRNLWENLLKSEQKNICDLFESIDSIKFEEELWFRKYKKNKNGGGGITRILQNGSVFEKCAVNYSCVFGTIDKDAAKQMCVNQYNKEYINTTKICHSEDINNIISKVMNSNNIRVVNEKYKFYASGISIIAHPINPNVPTIHSNFRFFQIFIKTGKKKKKNNLTNNKIGSNYKSIKHWFGGGCDLSPCYIFSDLFKKFHNSFKLICDKYNHLFYKYFKIWCDLYFRIKHRNINRGIGGIFFDNLLNNNIKYKKILKNGVSKEGNKNSLLEKKKCKCYSCNPIMDKSYRMIYLFIQECIIAFRKSYFHILLETINYKYDDNMIKWQRICRGRYVEFNLIYDRGTKFGIELNKFKTYRRKKKKKNIENFSSTNFIKDEIFDEQVSDYDSDEHEKISNVLSSLPLRCEFLYKYKVVKYSREYETLQILKHPKRWVDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVR2</accession>
    <name>A0A1J1GVR2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00413100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000064">
        <property type="protein sequence ID" value="CRG96549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529354.1">
        <property type="nucleotide sequence ID" value="XM_028672841.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVR2"/>
    <dbReference type="GeneID" id="39732661"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00413100"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="142" mass="16943" checksum="C0489C11CDA20B55" modified="2017-02-15" version="1">MKTFTLYLKIFTFLLLLWIFHYFYNDDSSKSLINKDTSQTKIGLKHKRMLAEGDKSEKNSSYIKKLVEHYPSGEIEISREDFVYLIQSYIKCYNANIKTNDVDQVKFNEENEMIYKCRDKILDSYINNISEEIELEQLSLTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW02</accession>
    <name>A0A1J1GW02_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00267800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000037">
        <property type="protein sequence ID" value="CRG95475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528285.1">
        <property type="nucleotide sequence ID" value="XM_028671654.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW02"/>
    <dbReference type="GeneID" id="39731207"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00267800"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="348" mass="42061" checksum="802B28049992DB62" modified="2017-02-15" version="1">MKMLTLCLKITTFLLLIWTYQCFYNCYSYKTLIDKNTMQIKNELKYRRVLTEGDIEGKKKTYVEGCLEECPLDKKKKKKKWKNPFKSKNPYYIWQRDTTPYLWEHFQNETSEMDPKWRDEKWSNEWKRISANKVNDLSSIFHRSDISKEEKERLIYSVEKELFTLFVEFLDKCKNEMRDNKTESESKKEMIDNRTEFEPKKETRDNKAESESEKEMRDNKTESESEKEMTDNKTESESEKETRDNKIEYESEKEMRDNKTESESEKEMRHNKEECESEKEMTDNNTKSESEKEMRDNKTESESTKVQGTNKIKNYKKKISKLIIVLIFLRRIKINGLTENIGLVMHKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW57</accession>
    <name>A0A1J1GW57_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Patatin-like phospholipase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00436900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PLPL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529590.1">
        <property type="nucleotide sequence ID" value="XM_028673104.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW57"/>
    <dbReference type="GeneID" id="39732901"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00436900"/>
    <dbReference type="OMA" id="WGNTALF"/>
    <dbReference type="OrthoDB" id="10049244at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050301">
        <property type="entry name" value="NTE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021771">
        <property type="entry name" value="Triacylglycerol_lipase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226">
        <property type="entry name" value="NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14226:SF66">
        <property type="entry name" value="TRIACYLGLYCEROL LIPASE PTL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11815">
        <property type="entry name" value="DUF3336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="38"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="249"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="PNPLA" evidence="8">
        <location>
            <begin position="443"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="651"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="5">
        <location>
            <begin position="477"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="669"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1015"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG96787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1015" mass="119594" checksum="1FC54D9CDADCDF2C" modified="2017-02-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW61</accession>
    <name>A0A1J1GW61_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Serine/threonine protein kinase, putative</fullName>
            <ecNumber evidence="7">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00372700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529307.1">
        <property type="nucleotide sequence ID" value="XM_028672790.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732257"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00372700"/>
    <dbReference type="OMA" id="EILYYMM"/>
    <dbReference type="OrthoDB" id="504170at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF30">
        <property type="entry name" value="MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="77"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="455"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="568"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="744"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="879"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1408"/>
            <end position="1435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="455"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="490"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="568"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="579"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1597" mass="187766" checksum="BF9798B975DAC375" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW64</accession>
    <name>A0A1J1GW64_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">tRNA(m1A58)-methyltransferase subunit TRM6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">GCD10</name>
        <name evidence="8" type="ORF">PGAL8A_00425500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRM6/GCD10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529479.1">
        <property type="nucleotide sequence ID" value="XM_028672981.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW64"/>
    <dbReference type="GeneID" id="39732787"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00425500"/>
    <dbReference type="OMA" id="CQFTVYE"/>
    <dbReference type="OrthoDB" id="10254665at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031515">
        <property type="term" value="C:tRNA (m1A) methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017423">
        <property type="entry name" value="TRM6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12945">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12945:SF0">
        <property type="entry name" value="TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT TRM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04189">
        <property type="entry name" value="Gcd10p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="351"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="411"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="358"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="383"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="413"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="438"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="626" mass="73896" checksum="ADDB211A50161F7F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWD2</accession>
    <name>A0A1J1GWD2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">COPI associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00281000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528421.1">
        <property type="nucleotide sequence ID" value="XM_028671805.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWD2"/>
    <dbReference type="GeneID" id="39731343"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00281000"/>
    <dbReference type="OMA" id="AKHRIMI"/>
    <dbReference type="OrthoDB" id="423534at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="262" mass="30646" checksum="04A33A8A09F845EE" modified="2017-02-15" version="1">MDSEYQGLLNSKEREDESNRAHIAEKVEKGGEKIENTLMKLNVRYQTLFFSSGVMTVLSGTISLLESLRYFYFTNFVVSTFLIIMGLIMMILDIPGTPRWAAKHRILIRKYIKFLTRLTGKSVWFFFLGSMSCLNLWPHSRNEGFFRSFLVILFSTFILVVSVVGFLIALRKSLRLEKLKKTIKLVSKGAYIDCYRKYSVADPDHGMQFEEFNRMCSDHTNGYIYFDFLDLFIIFNALDEHQKCSINEREFLEWINGPVTYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWE2</accession>
    <name>A0A1J1GWE2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">60S ribosomal protein L32, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPL32</name>
        <name evidence="4" type="ORF">PGAL8A_00416400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529387.1">
        <property type="nucleotide sequence ID" value="XM_028672879.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWE2"/>
    <dbReference type="GeneID" id="39732695"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00416400"/>
    <dbReference type="OMA" id="HPSGYEE"/>
    <dbReference type="OrthoDB" id="268693at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00513">
        <property type="entry name" value="Ribosomal_L32_L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001515">
        <property type="entry name" value="Ribosomal_eL32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018263">
        <property type="entry name" value="Ribosomal_eL32_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036351">
        <property type="entry name" value="Ribosomal_eL32_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23413">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L32 AND DNA-DIRECTED RNA POLYMERASE II, SUBUNIT N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23413:SF1">
        <property type="entry name" value="RIBOSOMAL PROTEIN L32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01655">
        <property type="entry name" value="Ribosomal_L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01393">
        <property type="entry name" value="Ribosomal_L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52042">
        <property type="entry name" value="Ribosomal protein L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00580">
        <property type="entry name" value="RIBOSOMAL_L32E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="131" mass="15557" checksum="B39B990BD42B515E" modified="2017-02-15" version="1">MAVKKVGKIIKKRTKKFTRFQSNRFMRVKPAWRKPRGIDCRVRRRYKGTNLMPSIGYGSNKKTRFLLPNNKYKYIVRNVKEMEPLIMNNTKYCVQIAHNVSSKKRKEIIERAKQINVSVINAKARLQKTEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWJ1</accession>
    <name>A0A1J1GWJ1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00450400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000078">
        <property type="protein sequence ID" value="CRG96923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529726.1">
        <property type="nucleotide sequence ID" value="XM_028673255.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWJ1"/>
    <dbReference type="GeneID" id="39733037"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00450400"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3030.10">
        <property type="entry name" value="Gametocyte protein Pfg27"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036469">
        <property type="entry name" value="Pfg27_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="401" mass="47869" checksum="5B45F0B94CD33A8F" modified="2017-02-15" version="1">MNILKAFNFYIILLVPYFLVFIPDFRLSPKSLKHILQIDYHEMKLISKRNLAESIPYVREFYSKTTDDNTFIEKDIFIDKFPYAEYLLSLELFNKVYNENYSIEQATGNMEAMLEKINSRFHFEGINIPLSEMFNIINRMTERTIEFSLESPETRKTLFKKILELEREATEELLKSLITGDEEVKINNRDNMDRILEIVQRRLIMQNISLLDSVVTKIATRISQFVESAINTYNERFKNPPWKNEEYVRLYSKLQYEVIENLLNIIYSANYYQTARDVFYDSKLIMETINDYSKRSNISLSYPQLRNMYIRVKECIRLVSLETISEARISNMLKIYRLESELVYEISMQILDSNVQEDEINYIDMTKDKTDYLLETENITLPEDVEKMAYRIRSYVLDIIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWN2</accession>
    <name>A0A1J1GWN2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alkaline phosphatase, putative</fullName>
            <ecNumber evidence="4">3.1.3.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00425100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.1" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529475.1">
        <property type="nucleotide sequence ID" value="XM_028672975.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWN2"/>
    <dbReference type="GeneID" id="39732783"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00425100"/>
    <dbReference type="OMA" id="EHGFETW"/>
    <dbReference type="OrthoDB" id="10266805at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004035">
        <property type="term" value="F:alkaline phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07389">
        <property type="entry name" value="MPP_PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.70">
        <property type="entry name" value="PhoD-like phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018946">
        <property type="entry name" value="PhoD-like_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33987">
        <property type="entry name" value="CALCINEURIN-LIKE METALLO-PHOSPHOESTERASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33987:SF1">
        <property type="entry name" value="CALCINEURIN-LIKE METALLO-PHOSPHOESTERASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09423">
        <property type="entry name" value="PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013085612" evidence="2">
        <location>
            <begin position="21"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="406"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="PhoD-like phosphatase metallophosphatase" evidence="3">
        <location>
            <begin position="82"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="444" mass="52712" checksum="DEF37AFA72E987D2" modified="2017-02-15" version="1">MKTRIKIFFIFFIFIKYVSSKADHIIHEKLTKFVFLSCNYQKSKKNEKLLESIEKIKPQLMLWIGDYFYSDCSELRCLDEAYNYIKKDPFYISLKEKFLIDGIYDDHDYNKNNGDRFYKYKEESKQKFLDYLNVDKNDVRYKRNGAYVSKLYIDPDNEKNQAKIIILDTRYNKDPYPFYAPDSYNDFFMCILISFLARFHSSIFGLHCNSKNDILGNEQWKWLENELTNSDARTHIIISSTQIFSNHVINENWGLMPYSLRRLKQLIKKTKPKGLIFLSGDVHFSSIIGNEDNIVEVTSSSVNQENVFSYLNKYFIYFFSSIINKRSAFELKNIYAFNNFGTVNINYIDDDEIRIKTSVNDSDGKEVLVANQIFNKKKNIYEKSDKLHVINDEFGTFMCKGKVKTFMHIIVYILFILWFIQILFILYKLFGIVKGSKVHKKKEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWQ0</accession>
    <name>A0A1J1GWQ0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA polymerase II subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00455900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA polymerase epsilon subunit B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529782.1">
        <property type="nucleotide sequence ID" value="XM_028673318.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWQ0"/>
    <dbReference type="GeneID" id="39733092"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00455900"/>
    <dbReference type="OMA" id="YCIGHVI"/>
    <dbReference type="OrthoDB" id="10254730at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008622">
        <property type="term" value="C:epsilon DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007185">
        <property type="entry name" value="DNA_pol_a/d/e_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016266">
        <property type="entry name" value="POLE2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12708:SF0">
        <property type="entry name" value="DNA POLYMERASE EPSILON SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12708">
        <property type="entry name" value="DNA POLYMERASE EPSILON SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04042">
        <property type="entry name" value="DNA_pol_E_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA polymerase alpha/delta/epsilon subunit B" evidence="7">
        <location>
            <begin position="365"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="624" mass="74091" checksum="E0B2B910FF818DBE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWT4</accession>
    <name>A0A1J1GWT4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00448100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529703.1">
        <property type="nucleotide sequence ID" value="XM_028673229.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWT4"/>
    <dbReference type="GeneID" id="39733014"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00448100"/>
    <dbReference type="OMA" id="YKEICPD"/>
    <dbReference type="OrthoDB" id="386946at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="550" mass="66144" checksum="E80CB0FF746E2B5C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWV3</accession>
    <name>A0A1J1GWV3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acyl-CoA synthetase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00460500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529828.1">
        <property type="nucleotide sequence ID" value="XM_028673369.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWV3"/>
    <dbReference type="GeneID" id="39733138"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00460500"/>
    <dbReference type="OMA" id="NRGELCV"/>
    <dbReference type="OrthoDB" id="1700726at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272:SF33">
        <property type="entry name" value="AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="4">
        <location>
            <begin position="99"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="4">
        <location>
            <begin position="332"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="270"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="271"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="282"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="317"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="808" mass="95035" checksum="1E28F1E08F44678F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWV6</accession>
    <name>A0A1J1GWV6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-i protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00270400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000040">
        <property type="protein sequence ID" value="CRG95503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528312.1">
        <property type="nucleotide sequence ID" value="XM_028671684.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWV6"/>
    <dbReference type="GeneID" id="39731235"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00270400"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="90"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="172"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="218" mass="25906" checksum="A46A499B49F324FC" modified="2017-02-15" version="1">MNLNLSDIIYIDSCETLDEEDSTAGFSHREIKDATVSIPENPLHDDLNSCDAIQNPSKDINLDSVTSKNLLHKKSLTKHEMRVRLQKILNNCNKKMKDDLEKEMREEKEKMEKNEKKLLKKKKEMEHREKGVLRHKEEWERKLKGNEVCDKSVLKVLKGREKRITEEGEKWKNRMLIEKMELEKKILKNKEEGEERMLKVIEKFEKEMQKEKESGKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX34</accession>
    <name>A0A1J1GX34_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00469400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529916.1">
        <property type="nucleotide sequence ID" value="XM_028673467.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733227"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00469400"/>
    <dbReference type="OMA" id="QHSNQDD"/>
    <dbReference type="OrthoDB" id="447390at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="381"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="433"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1099"/>
            <end position="1384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1659"/>
            <end position="1681"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="100"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1101"/>
            <end position="1126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1136"/>
            <end position="1168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1181"/>
            <end position="1198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1199"/>
            <end position="1354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1361"/>
            <end position="1372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1663"/>
            <end position="1680"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1932" mass="227666" checksum="56A78E25219E7B4E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX38</accession>
    <name>A0A1J1GX38_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">GTPase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00307300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528669.1">
        <property type="nucleotide sequence ID" value="XM_028672080.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX38"/>
    <dbReference type="GeneID" id="39731606"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00307300"/>
    <dbReference type="OMA" id="YVIDHRL"/>
    <dbReference type="OrthoDB" id="8954335at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043024">
        <property type="term" value="F:ribosomal small subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04163">
        <property type="entry name" value="Era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22534">
        <property type="entry name" value="KH-II_Era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030388">
        <property type="entry name" value="G_ERA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005662">
        <property type="entry name" value="GTPase_Era-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42698">
        <property type="entry name" value="GTPASE ERA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42698:SF1">
        <property type="entry name" value="GTPASE ERA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="Prokaryotic type KH domain (KH-domain type II)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G" evidence="5">
        <location>
            <begin position="93"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="205"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="493" mass="57788" checksum="7CEAB30BBEDC9756" modified="2017-02-15" version="1">MLKNILLNKINTKFNKGLYVRHFSILERYIRARPYSNELKINEESVNEEIKDENKKKDSKYYPPNITRGVIPKSAYMNIWKIPEQPENPKFLKIALIGPPNAGKSSLLNSILNKTISAVSPKINTTRQDIKGIYTKDNVQLIFIDAPGVIPSHKKKKFCKELVSYAWKGYEEADLVLFIVDTVKRPTNDIISIVRMLAPKRVDTDSSESEEENNEYDSECNNYRENLNENNINNYNEENIEGNEKKQNNNAISNNQNHEDIFLKEKDENKKLEEKFIKYFSGKMQNDLNYSDKSIKENIFDNRKKIIESYYDTQNINKNEKKVIPPVILVLNKVDLCTHNKWANARAKEFMNNGDFDNIFFISAKYNKGVEELLDYIIKYKAKNHLWIYPKDTSTTLTKVQIVEQLINTYLYCWFNKDVPYKIKHHMLSWCVNLNNCLIIEYQIIVKSEKVAKMICGVHNKLIINMRKNVSYKLTKLWGKNVYVHIHVKSVNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX77</accession>
    <name>A0A1J1GX77_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NEDD8-conjugating enzyme UBC12, putative</fullName>
            <ecNumber evidence="6">6.3.2.19</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">UBC12</name>
        <name evidence="6" type="ORF">PGAL8A_00466000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.19" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529882.1">
        <property type="nucleotide sequence ID" value="XM_028673429.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX77"/>
    <dbReference type="GeneID" id="39733193"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00466000"/>
    <dbReference type="OMA" id="NIDERGN"/>
    <dbReference type="OrthoDB" id="10249039at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd23794">
        <property type="entry name" value="UBCc_UBE2F_UBE2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="5">
        <location>
            <begin position="11"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="3">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="153" mass="17841" checksum="77D744DF2CC78010" modified="2017-02-15" version="1">MNNESIKKLKPFELILQKEIMDLDEMEGVELFLIDENNLREVGISITPKEGYFKNKNFKFLVKFKDSYPINPPKIICLNKIFHPNIDEKGNVCLNVLKLDWNPIINLQMLILGLLLLLNEPSTDDPFNQVAADIYKNDIVKFQEINNSIYQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXC5</accession>
    <name>A0A1J1GXC5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00478800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530012.1">
        <property type="nucleotide sequence ID" value="XM_028673573.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXC5"/>
    <dbReference type="GeneID" id="39733321"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00478800"/>
    <dbReference type="OMA" id="TIRALMF"/>
    <dbReference type="OrthoDB" id="5981550at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13365">
        <property type="entry name" value="PH_PLC_plant-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="1">
        <location>
            <begin position="282"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="881" mass="105421" checksum="D087D82DB07F951F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXE1</accession>
    <name>A0A1J1GXE1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein SEY1 homolog</fullName>
            <ecNumber evidence="10">3.6.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00287700</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Probable GTP-binding protein involved in generating and maintaining the structure of the tubular endoplasmic reticulum network.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Probable GTP-binding protein that may be involved in cell development.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Endoplasmic reticulum membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="10"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528488.1">
        <property type="nucleotide sequence ID" value="XM_028671880.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXE1"/>
    <dbReference type="GeneID" id="39731410"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00287700"/>
    <dbReference type="OrthoDB" id="1597724at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016320">
        <property type="term" value="P:endoplasmic reticulum membrane fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01851">
        <property type="entry name" value="GBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000727">
        <property type="entry name" value="Protein SEY1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03109">
        <property type="entry name" value="Sey1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030386">
        <property type="entry name" value="G_GB1_RHD3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008803">
        <property type="entry name" value="RHD3/Sey1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45923">
        <property type="entry name" value="PROTEIN SEY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45923:SF2">
        <property type="entry name" value="PROTEIN SEY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05879">
        <property type="entry name" value="RHD3_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51715">
        <property type="entry name" value="G_GB1_RHD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="topological domain" description="Cytoplasmic" evidence="10">
        <location>
            <begin position="1"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="topological domain" description="Lumenal" evidence="10">
        <location>
            <begin position="815"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="822"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="topological domain" description="Cytoplasmic" evidence="10">
        <location>
            <begin position="839"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="domain" description="GB1/RHD3-type G" evidence="12">
        <location>
            <begin position="35"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="45"/>
            <end position="52"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG95680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="881" mass="104305" checksum="A2C75183382B7E8F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXU7</accession>
    <name>A0A1J1GXU7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00488300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530106.1">
        <property type="nucleotide sequence ID" value="XM_028673678.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXU7"/>
    <dbReference type="GeneID" id="39733416"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00488300"/>
    <dbReference type="OMA" id="FSRWHIL"/>
    <dbReference type="OrthoDB" id="391350at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="745" mass="89108" checksum="3CC182B938167CAC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXV7</accession>
    <name>A0A1J1GXV7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Plasmodium RESA N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00376900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000097">
        <property type="protein sequence ID" value="CRG97396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530198.1">
        <property type="nucleotide sequence ID" value="XM_028673780.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXV7"/>
    <dbReference type="GeneID" id="39732299"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00376900"/>
    <dbReference type="OMA" id="HIMISHR"/>
    <dbReference type="OrthoDB" id="384212at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.180">
        <property type="entry name" value="Plasmodium RESA, N-terminal helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006526">
        <property type="entry name" value="Export_prot_PHISTa/b/c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019111">
        <property type="entry name" value="PRESA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044885">
        <property type="entry name" value="PRESA_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01639">
        <property type="entry name" value="P_fal_TIGR01639"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36193">
        <property type="entry name" value="PHISTB DOMAIN-CONTAINING RESA-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36193:SF23">
        <property type="entry name" value="PHISTB DOMAIN-CONTAINING RESA-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09687">
        <property type="entry name" value="PRESAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="Plasmodium RESA N-terminal" evidence="3">
        <location>
            <begin position="197"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="342" mass="41067" checksum="EB6D01FB56156CDF" modified="2017-02-15" version="1">MRHSNTINFILQRRFLVSNNASISNLDISSFNRGKKNFQKRIFSNFLFSKLFILYFFSVLYLFSLHICVSKDNAFSELQLNKVYDRKLAEHIPEKGEDSKKTKTNFDINEDKKSQSIYGSPGMSELNKSVKHNHDGMSELKKKEILEESDRIEKKNDKVRDNMDKRKMNDEMGKQKIQNEGCAISLGNRSSELHYQLCESEINERIQNLDDVPSIEDIYILWWQVRGDQRNNFFQIIDYLKKLFKSLTNKYNFDESFLNKEYNKWYRGVLYEFINMEANDNKNFYSLYKRESWTREKFKDFIDRNILVWNNYKISIKNKWENILTEDFINEEQKRTDNSQQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYG2</accession>
    <name>A0A1J1GYG2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00518300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530411.1">
        <property type="nucleotide sequence ID" value="XM_028674016.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYG2"/>
    <dbReference type="GeneID" id="39733716"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00518300"/>
    <dbReference type="OrthoDB" id="370410at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012158946" description="Transmembrane protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="208" mass="24819" checksum="D6BB4957B27E8773" modified="2017-02-15" version="1">MPKYFTFLTFLFLLIRYVHCDFIIVDSNKDVYNFDKNTVLNLSENVFNIFLDTKTNNSDIKVVYAEIYNKYKLAIEESCSYVKELIKGRNLKYLDEKETKEYIKSKDTYSFSIFVYTISGEPEVIQEVYKKHPKHISYIITCKENEIFDNIEDVKEYKNVFHTNPNILSQLIAIFLIFFFIIIGFYILMNISTPKTFEEKQLIINKEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYY1</accession>
    <name>A0A1J1GYY1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Eukaryotic translation initation factor 4 gamma, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">EIF4G</name>
        <name evidence="6" type="ORF">PGAL8A_00509200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic initiation factor 4G family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530320.1">
        <property type="nucleotide sequence ID" value="XM_028673915.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733625"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00509200"/>
    <dbReference type="OMA" id="TEKMCQI"/>
    <dbReference type="OrthoDB" id="514777at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016281">
        <property type="term" value="C:eukaryotic translation initiation factor 4F complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.180:FF:000049">
        <property type="entry name" value="Eukaryotic translation initation factor 4 gamma, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003890">
        <property type="entry name" value="MIF4G-like_typ-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23253">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23253:SF9">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00543">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MIF4G" evidence="5">
        <location>
            <begin position="1091"/>
            <end position="1314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="22"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="465"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="938"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="22"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="941"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="975"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="992"/>
            <end position="1067"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1384" mass="162403" checksum="C83890F5D811AA97" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ67</accession>
    <name>A0A1J1GZ67_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00510200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530330.1">
        <property type="nucleotide sequence ID" value="XM_028673926.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ67"/>
    <dbReference type="GeneID" id="39733635"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00510200"/>
    <dbReference type="OMA" id="NDARMTY"/>
    <dbReference type="OrthoDB" id="408027at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="371"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="105"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="138"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="248"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="331"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="400" mass="47147" checksum="2DA3426C3B0F6ECE" modified="2017-02-15" version="1">MSSKIWKVILKDDVKKFENCIKSEKNIDLNNYNKDGLTILLYGIEKGCAECCYYLINQKNVDVFLEDKKENENALMKSMRIGYEMINVSKLLIEKKVIINEKNKSGKTSLHIASENNYLKGIELLLKNNADINAVDNQNNTPLMSSIKRNNEESAFLLIDNNADVNIKDNDMNSVLHICAKEHLSNVAQYILSTNKVNIENCLDKDNNSPLHIAAKENLKSLCNLFLSYNFDGLLKNNKNETYNDILKKHEMNAILKEEEKKKNYEEKEIRRRKLYEETMLKTEVSNFLMNYNLESFIPHFYKYNYIYVDGAFLEIEDSTLKKMNFNRDERKKFYDAIEQFYKEKEDQENEAELRNQQLLEEQNRTKNLKYVSYVIFLIFTSIFIYSLFISITNRAKIFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZB2</accession>
    <name>A0A1J1GZB2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00536200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530585.1">
        <property type="nucleotide sequence ID" value="XM_028674209.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZB2"/>
    <dbReference type="GeneID" id="39733895"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00536200"/>
    <dbReference type="OrthoDB" id="407649at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63825">
        <property type="entry name" value="YWTD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="510" mass="59666" checksum="B4E20BA05C28A5C9" modified="2017-02-15" version="1">MENSLLNNSFFKKEDKYKNNYIKYQIPKRKFYNLIIRVAISVISIIIILIFVKYNNNNNNSNIVNFSIMEIDEDTNELFNSLGFPLNSKELIYSRLEKWGFNLSDIAEIEINPNFKEADLKKYKYSKNTYKDILFSYYENKKNSEIEKNILLYKFLEILKKKEINSFYDFLNYFMILQDLNCLPVNYKGIYVNEKFFVPNHLNQVKMVDKNFRTTLVNEKPFLYLTYHGGKKKNSIHNICKFSRDGYFLGSVLLPFEEEGKIFNCISLRGLLLYKDNLYVTDSFKNNSKIFQFSDSLTEFSNRREYLSTFISQNEKENPLMVHPYGIKRKDEYFYVSSQNTGTVLRFNVNNGKLDKSLNSKKNNSDGVVVKLHKNDEIRGIDFDNYGKCYVANKQTGVQVYDENFNLLKIIPVLSPISIVYDSRNSHILVGSSKSHDIKEYDIHNYELIKVVKHPLLRHVAGISIYGDSIFVVSQKKNKLLEFSLSTSLLKNIIVDDLSDTGERVMVSPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZJ8</accession>
    <name>A0A1J1GZJ8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00430100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529525.1">
        <property type="nucleotide sequence ID" value="XM_028673031.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZJ8"/>
    <dbReference type="GeneID" id="39732833"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00430100"/>
    <dbReference type="OrthoDB" id="370912at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="261"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="317" mass="37907" checksum="6CFCA653592415EF" modified="2017-02-15" version="1">MLYLEKLNSFIENKYVVSNWKKKKFVWRYSFFFSIFYILLVFGIVYTLIVRILISREKFSNHSCSSSRIMSVQSRYMEVLIFIILMGFINFFFSRLTYLYSNFTNSEFFNLGIYYTVVGFLIKYISWILSLIYMSWLFFLIINIITIFSSPNKWCSLKYNIYGMDALNNCLLVKNRATVIVLRKKESCNDFNILKVQSFLFLVRSSPNLVCSLKDKKLCDFFVDFIKNKQTSWESFPNCSGNTVDLREQYFLEDSDHKSNIYLFSISFILFWLVTTIILLTFIIVIKVNTPIDSSFIMNEERLNLFFKFTRLLDVWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZS8</accession>
    <name>A0A1J1GZS8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sin3 associated polypeptide p18-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00051500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SAP18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530877.1">
        <property type="nucleotide sequence ID" value="XM_028674535.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZS8"/>
    <dbReference type="GeneID" id="39729040"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00051500"/>
    <dbReference type="OMA" id="RNAQWIF"/>
    <dbReference type="OrthoDB" id="440566at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.550">
        <property type="entry name" value="ASAP complex, SAP18 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010516">
        <property type="entry name" value="SAP18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042534">
        <property type="entry name" value="SAP18_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13082:SF0">
        <property type="entry name" value="HISTONE DEACETYLASE COMPLEX SUBUNIT SAP18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13082">
        <property type="entry name" value="SAP18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06487">
        <property type="entry name" value="SAP18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="83"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="216"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="455"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="108"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="123"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="145"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="156"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="219"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="246"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="266"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="316"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="330"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="349"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="366"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="391"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="410"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="455"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="469"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="693" mass="83469" checksum="0AD265AB7C697576" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZT2</accession>
    <name>A0A1J1GZT2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein kinase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00439100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529613.1">
        <property type="nucleotide sequence ID" value="XM_028673129.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZT2"/>
    <dbReference type="GeneID" id="39732924"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00439100"/>
    <dbReference type="OrthoDB" id="354826at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055164">
        <property type="entry name" value="EDR1/CTR1/ARMC3-like_pept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050167">
        <property type="entry name" value="Ser_Thr_protein_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257:SF963">
        <property type="entry name" value="AT08303P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257">
        <property type="entry name" value="SERINE-THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14381">
        <property type="entry name" value="EDR1_CTR1_ARMC3_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="772"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="557"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="464"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1063" mass="127096" checksum="F8006343B6C60D88" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZZ7</accession>
    <name>A0A1J1GZZ7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">18S rRNA aminocarboxypropyltransferase</fullName>
            <ecNumber evidence="6">2.5.1.157</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">TSR3</name>
        <name evidence="11" type="ORF">PGAL8A_00534700</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>an N(1)-methylpseudouridine in rRNA + S-adenosyl-L-methionine = N(1)-methyl-N(3)-[(3S)-3-amino-3-carboxypropyl]pseudouridine in rRNA + S-methyl-5'-thioadenosine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:63296"/>
            <dbReference type="Rhea" id="RHEA-COMP:11634"/>
            <dbReference type="Rhea" id="RHEA-COMP:16310"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74890"/>
            <dbReference type="ChEBI" id="CHEBI:146234"/>
            <dbReference type="EC" id="2.5.1.157"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TDD superfamily. TSR3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.157" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530570.1">
        <property type="nucleotide sequence ID" value="XM_028674192.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZZ7"/>
    <dbReference type="GeneID" id="39733880"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00534700"/>
    <dbReference type="OMA" id="DCSWKSL"/>
    <dbReference type="OrthoDB" id="10262062at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106388">
        <property type="term" value="F:rRNA small subunit aminocarboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904047">
        <property type="term" value="F:S-adenosyl-L-methionine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01116">
        <property type="entry name" value="TSR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007209">
        <property type="entry name" value="RNaseL-inhib-like_metal-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022968">
        <property type="entry name" value="Tsr3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007177">
        <property type="entry name" value="Tsr3_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002621">
        <property type="entry name" value="PRK02287.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20426:SF0">
        <property type="entry name" value="18S RRNA AMINOCARBOXYPROPYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20426">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN TSR3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04068">
        <property type="entry name" value="Fer4_RLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04034">
        <property type="entry name" value="Ribo_biogen_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNase L inhibitor RLI-like possible metal-binding" evidence="10">
        <location>
            <begin position="138"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="16S/18S rRNA aminocarboxypropyltransferase Tsr3 C-terminal" evidence="9">
        <location>
            <begin position="175"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="91"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="17"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="91"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG97769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="324" mass="38954" checksum="2E2CE1F2FC4AC87C" modified="2017-02-15" version="1">MKKSYLERKKYSVHNLIKIINERKREKERNNENIESTKKKLEDENSKICNKIEKKKEKKEKEELNLDNMKKVDSSSQSIIEFDERNGCTREINDKKKPNYENDISDDKDEFTNESNDEENQCTSEYSDNIKKDIDEIKLFMIDYKECQNKKCSCKKLYRFKKIKKVQTNKKFKGIVLTPFCEKYFSINDKYTVEKFGLSVIDCSWKSLDLLKKIKYSNQRKLPYIIAVNSINYGKPYKLSCLESLAFCLYICNYTQQCNDILNIYKWSINFTNLNKELLDKYKLCKNHDEIKKAESEFIENYLDEKEENKKIDQYKVIYEDNYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H019</accession>
    <name>A0A1J1H019_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Regulator of chromosome condensation, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00051600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530878.1">
        <property type="nucleotide sequence ID" value="XM_028674536.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H019"/>
    <dbReference type="GeneID" id="39729041"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00051600"/>
    <dbReference type="OMA" id="CGGNNTF"/>
    <dbReference type="OrthoDB" id="61110at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051553">
        <property type="entry name" value="Ran_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058923">
        <property type="entry name" value="RCC1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982:SF1">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25390">
        <property type="entry name" value="WD40_RLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00625">
        <property type="entry name" value="RCC1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="6"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="RCC1-like" evidence="5">
        <location>
            <begin position="8"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="59"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="3">
        <location>
            <begin position="329"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="559"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="559"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="580"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="607"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="625"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="640"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="711"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="736"/>
            <end position="755"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF25390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG98081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="773" mass="89591" checksum="5597603972EB5FAE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H096</accession>
    <name>A0A1J1H096_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Zinc finger protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00060400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530966.1">
        <property type="nucleotide sequence ID" value="XM_028674633.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H096"/>
    <dbReference type="GeneID" id="39729129"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00060400"/>
    <dbReference type="OMA" id="NDDHTFF"/>
    <dbReference type="OrthoDB" id="19329at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041661">
        <property type="entry name" value="ZN622/Rei1/Reh1_Znf-C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040025">
        <property type="entry name" value="Znf622/Rei1/Reh1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13182:SF8">
        <property type="entry name" value="CYTOPLASMIC 60S SUBUNIT BIOGENESIS FACTOR ZNF622"/>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR13182">
        <property type="entry name" value="ZINC FINGER PROTEIN 622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12756">
        <property type="entry name" value="zf-C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ZN622/Rei1/Reh1 zinc finger C2H2-type" evidence="2">
        <location>
            <begin position="187"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="541" mass="65406" checksum="93491DAD53ABC82F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0C0</accession>
    <name>A0A1J1H0C0_PLAGA</name>
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        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00044200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530808.1">
        <property type="nucleotide sequence ID" value="XM_028674458.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728967"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00044200"/>
    <dbReference type="OMA" id="ENYFWYY"/>
    <dbReference type="OrthoDB" id="378550at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="175"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="304"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="331"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="357"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="397"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1165"/>
            <end position="1186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1592"/>
            <end position="1651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1911"/>
            <end position="1931"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2357"/>
            <end position="2377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2435"/>
            <end position="2463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3262"/>
            <end position="3287"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="105"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="673"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2185"/>
            <end position="2218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1614"/>
            <end position="1637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1911"/>
            <end position="1922"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2439"/>
            <end position="2463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="3262"/>
            <end position="3280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG98011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3364" mass="397440" checksum="2A9C76DB964557FF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0U3</accession>
    <name>A0A1J1H0U3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA polymerase</fullName>
            <ecNumber evidence="12">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PGAL8A_00062600</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="12"/>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530984.1">
        <property type="nucleotide sequence ID" value="XM_028674653.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729151"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00062600"/>
    <dbReference type="OMA" id="GRNLLQH"/>
    <dbReference type="OrthoDB" id="6755010at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005658">
        <property type="term" value="C:alpha DNA polymerase:primase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006273">
        <property type="term" value="P:lagging strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006272">
        <property type="term" value="P:leading strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902975">
        <property type="term" value="P:mitotic DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05532">
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    </dbReference>
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        <property type="entry name" value="DNA_pol_B_thumb"/>
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        <property type="entry name" value="POLBc_alpha"/>
    </dbReference>
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        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="DNA POLYMERASE ALPHA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DNA POLYMERASE ALPHA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DNAPOLB"/>
    </dbReference>
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        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="DNA_POLYMERASE_B"/>
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    </dbReference>
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    <keyword evidence="10 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 12" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 12 15" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
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    <keyword evidence="3 12 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNA-directed DNA polymerase family B multifunctional" evidence="14">
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            <begin position="785"/>
            <end position="1246"/>
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            <begin position="46"/>
            <end position="76"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="13">
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            <end position="218"/>
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    </feature>
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            <end position="501"/>
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            <end position="896"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1420"/>
            <end position="1441"/>
        </location>
    </feature>
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        <location>
            <begin position="480"/>
            <end position="489"/>
        </location>
    </feature>
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        <location>
            <begin position="490"/>
            <end position="500"/>
        </location>
    </feature>
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            <end position="896"/>
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            <begin position="1420"/>
            <end position="1431"/>
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        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1567"/>
        </location>
    </feature>
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            <dbReference type="ARBA" id="ARBA00004123"/>
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    </evidence>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00022695"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00023125"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
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        </source>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="CRG98187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1567" mass="185273" checksum="326D2840D0FAE3AD" modified="2017-02-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H125</accession>
    <name>A0A1J1H125_PLAGA</name>
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        <submittedName>
            <fullName evidence="6">Homocysteine S-methyltransferase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00455300</name>
    </gene>
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        <name type="scientific">Plasmodium gallinaceum</name>
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            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:S-adenosylmethionine-homocysteine S-methyltransferase activity"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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        <property type="entry name" value="HCY_dom"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
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            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="Hcy-binding" evidence="5">
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            <begin position="318"/>
            <end position="512"/>
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    </feature>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="520" mass="61503" checksum="BE5AD259EC9B7B67" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H138</accession>
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    <protein>
        <recommendedName>
            <fullName evidence="2">H(+)-exporting diphosphatase</fullName>
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        </recommendedName>
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        <name evidence="12" type="ORF">PGAL8A_00456900</name>
    </gene>
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        <name type="scientific">Plasmodium gallinaceum</name>
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        <lineage>
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            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="protein sequence ID" value="CRG96989.1"/>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_028673329.1"/>
    </dbReference>
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    <dbReference type="OMA" id="MATTAMQ"/>
    <dbReference type="OrthoDB" id="5210at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009678">
        <property type="term" value="F:diphosphate hydrolysis-driven proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01129">
        <property type="entry name" value="PPase_energized_pump"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004131">
        <property type="entry name" value="PPase-energised_H-pump"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31998">
        <property type="entry name" value="K(+)-INSENSITIVE PYROPHOSPHATE-ENERGIZED PROTON PUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03030">
        <property type="entry name" value="H_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="329"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="374"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="424"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="462"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="565"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="662"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="691"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="750"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="780"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="845"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="884"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="955"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="985"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="165"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG96989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1076" mass="119261" checksum="932F1EE3DF7D3A9D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1Q7</accession>
    <name>A0A1J1H1Q7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="25">Dynein heavy chain, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">PGAL8A_00482400</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="25" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="25">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynein heavy chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="25">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530048.1">
        <property type="nucleotide sequence ID" value="XM_028673613.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733357"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00482400"/>
    <dbReference type="OMA" id="KLPCAIW"/>
    <dbReference type="OrthoDB" id="424310at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097729">
        <property type="term" value="C:9+2 motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008569">
        <property type="term" value="F:minus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060294">
        <property type="term" value="P:cilium movement involved in cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.710:FF:000001">
        <property type="entry name" value="Dynein axonemal heavy chain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.490.20:FF:000009">
        <property type="entry name" value="Dynein heavy chain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000063">
        <property type="entry name" value="dynein heavy chain 6, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.720:FF:000009">
        <property type="entry name" value="Dynein heavy chain, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.20:FF:000010">
        <property type="entry name" value="Dynein heavy chain, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001266">
        <property type="entry name" value="Dynein heavy chain, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.100">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.180.20">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.720">
        <property type="entry name" value="Region D6 of dynein motor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035699">
        <property type="entry name" value="AAA_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035706">
        <property type="entry name" value="AAA_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041658">
        <property type="entry name" value="AAA_lid_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042219">
        <property type="entry name" value="AAA_lid_11_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011704">
        <property type="entry name" value="ATPase_dyneun-rel_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041589">
        <property type="entry name" value="DNAH3_AAA_lid_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042222">
        <property type="entry name" value="Dynein_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043157">
        <property type="entry name" value="Dynein_AAA1S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041228">
        <property type="entry name" value="Dynein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043160">
        <property type="entry name" value="Dynein_C_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024743">
        <property type="entry name" value="Dynein_HC_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024317">
        <property type="entry name" value="Dynein_heavy_chain_D4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004273">
        <property type="entry name" value="Dynein_heavy_D6_P-loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013602">
        <property type="entry name" value="Dynein_heavy_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042228">
        <property type="entry name" value="Dynein_linker_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10676:SF36">
        <property type="entry name" value="DYNEIN HEAVY CHAIN AT 93AB, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10676">
        <property type="entry name" value="DYNEIN HEAVY CHAIN FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07728">
        <property type="entry name" value="AAA_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12774">
        <property type="entry name" value="AAA_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12775">
        <property type="entry name" value="AAA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12780">
        <property type="entry name" value="AAA_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12781">
        <property type="entry name" value="AAA_9"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17857">
        <property type="entry name" value="AAA_lid_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18198">
        <property type="entry name" value="AAA_lid_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08393">
        <property type="entry name" value="DHC_N2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18199">
        <property type="entry name" value="Dynein_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03028">
        <property type="entry name" value="Dynein_heavy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12777">
        <property type="entry name" value="MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0966">Cell projection</keyword>
    <keyword evidence="9" id="KW-0969">Cilium</keyword>
    <keyword evidence="8 13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0243">Dynein</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-0505">Motor protein</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynein heavy chain linker" evidence="17">
        <location>
            <begin position="1384"/>
            <end position="1521"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain linker" evidence="17">
        <location>
            <begin position="1540"/>
            <end position="1801"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain hydrolytic ATP-binding dynein motor region" evidence="18">
        <location>
            <begin position="2058"/>
            <end position="2353"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase dynein-related AAA" evidence="16">
        <location>
            <begin position="2466"/>
            <end position="2604"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain 3 AAA+ lid" evidence="22">
        <location>
            <begin position="3189"/>
            <end position="3267"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain AAA module D4" evidence="20">
        <location>
            <begin position="3404"/>
            <end position="3662"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain coiled coil stalk" evidence="19">
        <location>
            <begin position="3675"/>
            <end position="4013"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain ATP-binding dynein motor region" evidence="21">
        <location>
            <begin position="4039"/>
            <end position="4150"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain ATP-binding dynein motor region" evidence="21">
        <location>
            <begin position="4193"/>
            <end position="4325"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain region D6 P-loop" evidence="15">
        <location>
            <begin position="4630"/>
            <end position="4745"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain AAA lid" evidence="23">
        <location>
            <begin position="4776"/>
            <end position="4917"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain C-terminal" evidence="24">
        <location>
            <begin position="4923"/>
            <end position="5225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="591"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="2385"/>
            <end position="2421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="2704"/>
            <end position="2747"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="2894"/>
            <end position="2948"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="1274"/>
            <end position="1330"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="1810"/>
            <end position="1867"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="3688"/>
            <end position="3725"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="3886"/>
            <end position="3969"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="601"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="2389"/>
            <end position="2420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="2704"/>
            <end position="2719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="2727"/>
            <end position="2747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="2896"/>
            <end position="2932"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF03028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF07728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF08393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF12774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF12777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF12780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF12781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF17857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF18198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF18199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="CRG97245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="5230" mass="618602" checksum="7FAD27707D4E2B9F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2F8</accession>
    <name>A0A1J1H2F8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00509100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530319.1">
        <property type="nucleotide sequence ID" value="XM_028673914.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733624"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00509100"/>
    <dbReference type="OMA" id="YYLSFSE"/>
    <dbReference type="OrthoDB" id="377686at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1450"/>
            <end position="1477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1587"/>
            <end position="1608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1450"/>
            <end position="1460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1461"/>
            <end position="1477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1911" mass="226881" checksum="442B1A9261C79C86" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2R0</accession>
    <name>A0A1J1H2R0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00534900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530572.1">
        <property type="nucleotide sequence ID" value="XM_028674194.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2R0"/>
    <dbReference type="GeneID" id="39733882"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00534900"/>
    <dbReference type="OMA" id="INNFYEC"/>
    <dbReference type="OrthoDB" id="392343at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="91"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="627" mass="75925" checksum="6E7F47028852647B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2T8</accession>
    <name>A0A1J1H2T8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00023900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530604.1">
        <property type="nucleotide sequence ID" value="XM_028674230.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2T8"/>
    <dbReference type="GeneID" id="39728762"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00023900"/>
    <dbReference type="OMA" id="RRLCMPI"/>
    <dbReference type="OrthoDB" id="330093at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="335" mass="39978" checksum="DF2EAD5A5B050CE4" modified="2017-02-15" version="1">MFYLCPKKLGGGVGRRLCMPIYSGSSDSVFKYKNFVLKKIKHKYENVLLFGDIHKLRMTAEELIKNVISNDNIDNDYNNYKLQKYMYNKTEKIKKASNDDIEKDKSSKNKNSITKKLSFWQIYSIRVKKNIHLLNFFDFALILQSFHLYNKDTGIYVSSIKYIEDQIPVMNGISFVIILNILSKRLKKNNYNEFFKKMMNYLPNILYELNLKDMSNILNCFYNLELNDKKVCELFYLKILSNINKIDALTLSSLCYIFYKYNFENIHFFECLKKTGFNLLDDFDANQFYKFIFSLYKKKICLKEIIEKKKNDILSFLPNYSDEEKLFICEIFNLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2W2</accession>
    <name>A0A1J1H2W2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00525400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530479.1">
        <property type="nucleotide sequence ID" value="XM_028674092.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2W2"/>
    <dbReference type="GeneID" id="39733787"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00525400"/>
    <dbReference type="OrthoDB" id="373683at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="142" mass="17005" checksum="C866A1FAAF80AC14" modified="2017-02-15" version="1">MFELFHDIYKTLSCYKTIRKVNNFVHTNKEKINNEELEVINENKYISHTLAFLTALGIQTSFYKLKRFKFFAFRPFLPSFLGVITSCSFLYLHTLYLSRNTISKLIQLNLKKINEEGICIYVDEIYKKEEPDDYIYLKNKVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3V5</accession>
    <name>A0A1J1H3V5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Replication protein A1, large subunit, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">RPA1</name>
        <name evidence="13" type="ORF">PGAL8A_00060200</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the replication factor A protein 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530964.1">
        <property type="nucleotide sequence ID" value="XM_028674630.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3V5"/>
    <dbReference type="GeneID" id="39729127"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00060200"/>
    <dbReference type="OrthoDB" id="1751331at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04474">
        <property type="entry name" value="RPA1_DBD_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04475">
        <property type="entry name" value="RPA1_DBD_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04476">
        <property type="entry name" value="RPA1_DBD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000041">
        <property type="entry name" value="Replication protein A subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000064">
        <property type="entry name" value="Replication protein A subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047192">
        <property type="entry name" value="Euk_RPA1_DBD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013955">
        <property type="entry name" value="Rep_factor-A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031657">
        <property type="entry name" value="REPA_OB_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47165">
        <property type="entry name" value="OS03G0429900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47165:SF4">
        <property type="entry name" value="OS03G0429900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08646">
        <property type="entry name" value="Rep_fac-A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16900">
        <property type="entry name" value="REPA_OB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="OB" evidence="10">
        <location>
            <begin position="552"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="domain" description="Replication protein A OB" evidence="12">
        <location>
            <begin position="659"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="domain" description="Replication factor A C-terminal" evidence="11">
        <location>
            <begin position="820"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="287"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="287"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="316"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF16900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG98167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="995" mass="116454" checksum="D8694C31D3FA542A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2012-07-11" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>I2FKD0</accession>
    <name>I2FKD0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">fumarate hydratase</fullName>
            <ecNumber evidence="5">4.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">FUM</name>
        <name evidence="15" type="ORF">PGAL8A_00440100</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Gene" volume="502" first="36" last="39">
            <title>Age of the last common ancestor of extant Plasmodium parasite lineages.</title>
            <authorList>
                <person name="Hayakawa T."/>
                <person name="Tachibana S."/>
                <person name="Hikosaka K."/>
                <person name="Arisue N."/>
                <person name="Matsui A."/>
                <person name="Horii T."/>
                <person name="Tanabe K."/>
            </authorList>
            <dbReference type="PubMed" id="22555021"/>
            <dbReference type="DOI" id="10.1016/j.gene.2012.04.037"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; tricarboxylic acid cycle; (S)-malate from fumarate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-I fumarase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.2" evidence="5"/>
    <dbReference type="EMBL" id="AB571139">
        <property type="protein sequence ID" value="BAM15615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="I2FKD0"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00440100"/>
    <dbReference type="OMA" id="AGVLPMC"/>
    <dbReference type="OrthoDB" id="411469at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004333">
        <property type="term" value="F:fumarate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.130.10">
        <property type="entry name" value="Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051208">
        <property type="entry name" value="Class-I_Fumarase/Tartrate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004646">
        <property type="entry name" value="Fe-S_hydro-lyase_TtdA-typ_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004647">
        <property type="entry name" value="Fe-S_hydro-lyase_TtdB-typ_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036660">
        <property type="entry name" value="Fe-S_hydroAse_TtdB_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011167">
        <property type="entry name" value="Fe_dep_fumarate_hydratase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00723">
        <property type="entry name" value="ttdB_fumA_fumB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30389:SF0">
        <property type="entry name" value="FUMARATE HYDRATASE CLASS I, AEROBIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30389">
        <property type="entry name" value="FUMARATE HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05681">
        <property type="entry name" value="Fumerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05683">
        <property type="entry name" value="Fumerase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001394">
        <property type="entry name" value="Fe_dep_fumar_hy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117457">
        <property type="entry name" value="FumA C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11 15" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Fe-S hydro-lyase tartrate dehydratase alpha-type catalytic" evidence="12">
        <location>
            <begin position="124"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="Fe-S hydro-lyase tartrate dehydratase beta-type catalytic" evidence="13">
        <location>
            <begin position="431"/>
            <end position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF05681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF05683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="BAM15615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG96820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="641" mass="73187" checksum="2BF2D1AA56ED3F32" modified="2012-07-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKZ7</accession>
    <name>A0A1J1GKZ7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Iron-sulfur assembly protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">SufA</name>
        <name evidence="5" type="ORF">PGAL8A_00069900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; iron-sulfur cluster biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG92995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525817.1">
        <property type="nucleotide sequence ID" value="XM_028673421.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKZ7"/>
    <dbReference type="GeneID" id="39729224"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00069900"/>
    <dbReference type="OMA" id="QTCEPAD"/>
    <dbReference type="OrthoDB" id="333486at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009570">
        <property type="term" value="C:chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="entry name" value="HesB-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016092">
        <property type="entry name" value="ATAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000361">
        <property type="entry name" value="ATAP_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017870">
        <property type="entry name" value="FeS_cluster_insertion_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031108">
        <property type="entry name" value="IscA_plant_cyanobact"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00049">
        <property type="entry name" value="iron-sulfur cluster assembly accessory protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47265">
        <property type="entry name" value="IRON-SULFUR ASSEMBLY PROTEIN ISCA, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47265:SF1">
        <property type="entry name" value="IRON-SULFUR ASSEMBLY PROTEIN ISCA, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01521">
        <property type="entry name" value="Fe-S_biosyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="HesB-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01152">
        <property type="entry name" value="HESB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012927111" evidence="3">
        <location>
            <begin position="19"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="Core" evidence="4">
        <location>
            <begin position="62"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG92995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="171" mass="20022" checksum="6B7C6BB34D1B47F9" modified="2017-02-15" version="1">MLVHTFFYFSIALKIINALRMSVFTSYINSLNTFPNKNKLRRKYMNRLKLVDESIKNNEHIIKLTDNAERKIKELVKEKEEDFLILKLFVQNGGCKGLQYKLNPIKKDEIEDDDYIQQFENLRFILSIDSTSVIYVFNNTLDYNNDLINGGFKFINPNATKKCGCGKSFNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLH7</accession>
    <name>A0A1J1GLH7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Armadillo repeats-only protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ARO</name>
        <name evidence="1" type="ORF">PGAL8A_00088300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526001.1">
        <property type="nucleotide sequence ID" value="XM_028671366.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLH7"/>
    <dbReference type="GeneID" id="39729407"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00088300"/>
    <dbReference type="OMA" id="YCCAGRD"/>
    <dbReference type="OrthoDB" id="7537227at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000349">
        <property type="entry name" value="Armadillo-domain containing rhoptry protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="275" mass="30986" checksum="7AB11C3EFBE30639" modified="2017-02-15" version="1">MGNYCCAGRDLLYKNKLHEFGKEGSKTLRKLLSFTSNDILRFDKAYDENDVQEFVNLCSSTCEIEKLEDRMHPWAADPKTIGALSATQLAILASKENEPHYKDAIREADGIPVFINLLKSHELDRIHASVVALSFLSVDNVKNCICMFENGALPYLISGMKSNIDGMKAACAQTCRNIFVLDKKYKKEFLKLGGITQLVNLLELPSNYDDNQPLYTQLEAIYHLEDFILNDGDEIPEFLEAVKNSNAIDNLKNLQQCPEQDLAEASNVLLLRLTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLK8</accession>
    <name>A0A1J1GLK8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Zinc finger, C3HC4 type, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00096300</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526079.1">
        <property type="nucleotide sequence ID" value="XM_028672233.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729487"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00096300"/>
    <dbReference type="OMA" id="GHAICKS"/>
    <dbReference type="OrthoDB" id="1933281at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034657">
        <property type="term" value="C:GID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045098">
        <property type="entry name" value="Fyv10_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044063">
        <property type="entry name" value="ZF_RING_GID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027370">
        <property type="entry name" value="Znf-RING_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12170:SF3">
        <property type="entry name" value="GH10162P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12170">
        <property type="entry name" value="MACROPHAGE ERYTHROBLAST ATTACHER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13445">
        <property type="entry name" value="zf-RING_UBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51867">
        <property type="entry name" value="ZF_RING_GID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-Gid-type" evidence="9">
        <location>
            <begin position="1805"/>
            <end position="1848"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="1805"/>
            <end position="1848"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="RING-Gid-type" evidence="5">
        <location>
            <begin position="1805"/>
            <end position="1848"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="257"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="940"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1029"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1155"/>
            <end position="1222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1267"/>
            <end position="1544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1578"/>
            <end position="1704"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="40"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="614"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="257"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="960"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1155"/>
            <end position="1164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1183"/>
            <end position="1210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1211"/>
            <end position="1222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1267"/>
            <end position="1471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1494"/>
            <end position="1544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1579"/>
            <end position="1651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1679"/>
            <end position="1698"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG93257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1863" mass="221542" checksum="FEE6D09C0D060167" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLU1</accession>
    <name>A0A1J1GLU1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00110500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526222.1">
        <property type="nucleotide sequence ID" value="XM_028673821.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLU1"/>
    <dbReference type="GeneID" id="39729631"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00110500"/>
    <dbReference type="OMA" id="SNCEDEF"/>
    <dbReference type="OrthoDB" id="366327at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13037">
        <property type="entry name" value="FORMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13037:SF24">
        <property type="entry name" value="POLYCOMB PROTEIN PCL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0945">Host-virus interaction</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="52"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="654"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="557"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="16"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="76"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="124"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="662"/>
            <end position="695"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="975" mass="113292" checksum="F14067CA04DACE0F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM79</accession>
    <name>A0A1J1GM79_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Dynamin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00114100</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526257.1">
        <property type="nucleotide sequence ID" value="XM_028674210.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM79"/>
    <dbReference type="GeneID" id="39729666"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00114100"/>
    <dbReference type="OMA" id="YEFETNH"/>
    <dbReference type="OrthoDB" id="1716625at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027094">
        <property type="entry name" value="Mitofusin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10465:SF4">
        <property type="entry name" value="DYNAMIN N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10465">
        <property type="entry name" value="TRANSMEMBRANE GTPASE FZO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="393"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="449"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="Dynamin N-terminal" evidence="8">
        <location>
            <begin position="115"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="35"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="514" mass="60646" checksum="182BE207E76432DA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMP2</accession>
    <name>A0A1J1GMP2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Liver merozoite formation protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">PALM</name>
        <name evidence="1" type="ORF">PGAL8A_00130800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526425.1">
        <property type="nucleotide sequence ID" value="XM_028674833.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMP2"/>
    <dbReference type="GeneID" id="39729833"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00130800"/>
    <dbReference type="OrthoDB" id="374862at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0477">Merozoite</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="301" mass="36272" checksum="63E55DBCC49D0153" modified="2017-02-15" version="1">MKLRFYNFFLILYFFLCICYGKKVLFINILNGINVNYNKKHINKNVSYNDNFSNQALFLNKNVTQQNKTKEINPVKVDETNENILRQYIYTLSHLTIFDTDREKDIPLNISLLLKACLASHNYIKNVEIYTSQVQNKEVCSFIYENSKDFENFFNIHVSKYSEFFNNPKISETLKLYINDKNLYENELEIYNKINKNTTLRKDILQDILFECIRTNKIVQYSLAVNKFNLFSYHTLSKVFMYFKSNDLYYDIFLNNIKKIKYYYGTKNIKEEDKKKIYSIIDNYLYILNYMNEMFENGNIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMQ0</accession>
    <name>A0A1J1GMQ0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00134900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526466.1">
        <property type="nucleotide sequence ID" value="XM_028674879.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMQ0"/>
    <dbReference type="GeneID" id="39729874"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00134900"/>
    <dbReference type="OMA" id="ITDSHKT"/>
    <dbReference type="OrthoDB" id="376134at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="124" mass="14684" checksum="DD007606FC813FF4" modified="2017-02-15" version="1">MNLDIYDNEKCLSLNGINKMVDDVYNDNLNFLLKKNKNELEKREIDQFSFKIEALLISLEEETKILHKEKDEIKKIFQNIAIQLKNVKKSIKKAEQYMGKNLNEGIIENSYKIFEDIKKDIDNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN24</accession>
    <name>A0A1J1GN24_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14 16">Ornithine aminotransferase</fullName>
            <ecNumber evidence="6 16">2.6.1.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">OAT</name>
        <name evidence="17" type="ORF">PGAL8A_00137400</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-ornithine + 2-oxoglutarate = L-glutamate 5-semialdehyde + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:25160"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="EC" id="2.6.1.13"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:25161"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 16">
            <text>a 2-oxocarboxylate + L-ornithine = L-glutamate 5-semialdehyde + an L-alpha-amino acid</text>
            <dbReference type="Rhea" id="RHEA:13877"/>
            <dbReference type="ChEBI" id="CHEBI:35179"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="ChEBI" id="CHEBI:59869"/>
            <dbReference type="EC" id="2.6.1.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 16">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 16">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-ornithine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.13" evidence="6 16"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526491.1">
        <property type="nucleotide sequence ID" value="XM_028674907.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN24"/>
    <dbReference type="GeneID" id="39729899"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00137400"/>
    <dbReference type="OMA" id="VCEGNFH"/>
    <dbReference type="OrthoDB" id="425114at2759"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00358"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004587">
        <property type="term" value="F:ornithine aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019544">
        <property type="term" value="P:L-arginine catabolic process to L-glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010121">
        <property type="term" value="P:L-arginine catabolic process to proline via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000011">
        <property type="entry name" value="Ornithine aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000152">
        <property type="entry name" value="Ornithine aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049704">
        <property type="entry name" value="Aminotrans_3_PPA_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050103">
        <property type="entry name" value="Class-III_PLP-dep_AT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010164">
        <property type="entry name" value="Orn_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01885">
        <property type="entry name" value="Orn_aminotrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986">
        <property type="entry name" value="AMINOTRANSFERASE CLASS III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986:SF18">
        <property type="entry name" value="ORNITHINE AMINOTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 16 17" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10 15" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 16 17" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00051265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00051944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00073894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU365036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="CRG93669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="414" mass="46136" checksum="51ABFDE27D87341D" modified="2017-02-15" version="1">MSSIKELKTSQDYMNNELTYGAHNYDPIPVVLTKGEGIFVYDVENKRYYDFLSSYSSVNQGHCHPDILNAMIKQAEKLTICSRAFFSDTLGLCERYLANLFGYDKVLMMNSGAEANETAYKICRKWGYEVKKIPENSAKIIVCTNNFSGRTLGCISASTDHICKNNFGPFVPNFIKVEYNNLVELEKELKDPNVCAFFVEPIQGEAGVIIPSENYLSGVYDLCKKYNVLFVTDEIQTALGRTGKMLCSQHSNVKPDIVLLGKALSGGYYPISAVLANNDVMLVLKPGEHGSTYGGNPLASAICIAAVEVIIKEKLCENAEKLGPYFLNSLKKELKESKIVHDVRGKGLFCAVEFNNSLVNVKDICIKLKENGLLTKPVHERTIRLSPPLCITKEHLNECVQIISKTIKCFDDLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN93</accession>
    <name>A0A1J1GN93_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00156100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526674.1">
        <property type="nucleotide sequence ID" value="XM_028675109.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN93"/>
    <dbReference type="GeneID" id="39730086"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00156100"/>
    <dbReference type="OMA" id="KYTHEYT"/>
    <dbReference type="OrthoDB" id="371631at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="352" mass="41545" checksum="FCF2CECA9B26EEB6" modified="2017-02-15" version="1">MEKIIDNKMNISDENNFKNINDNKKNYVNENLKNKFDEKIDYLDKTLGNKFDKKIKEEKSIYDKNTDIRIYENQISKKKKRAFTLGAIDGIGDISILKAPLINPENPKVEPPILQLPSATNLIKNIHLKINFDKNIDKSYKYRTQNSNKDIINNMKPLYSLPEKVMTYYMNTNNEQGEEWNVNRNTKYCVNESNKEKKDEDEKKEEKYEKKKDSENRILIDTLSDKKEIEFSKKENISNKEVNLHRNTISSNNNNNHISRKEKSMQLSKAKLIQKNEENKQFKNNNDFYKDSLENSNFYKDNFNHDKHFNEGNLYKIFNNKSNDELKLLEANHIMSSTLANALKKLADDVFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNE2</accession>
    <name>A0A1J1GNE2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">nicotinate phosphoribosyltransferase</fullName>
            <ecNumber evidence="3">6.3.4.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">NAPRT</name>
        <name evidence="13" type="ORF">PGAL8A_00157600</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Helps prevent cellular oxidative stress via its role in NAD biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>5-phospho-alpha-D-ribose 1-diphosphate + nicotinate + ATP + H2O = nicotinate beta-D-ribonucleotide + ADP + phosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:36163"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32544"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57502"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAPRTase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.21" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526689.1">
        <property type="nucleotide sequence ID" value="XM_028675127.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNE2"/>
    <dbReference type="GeneID" id="39730101"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00157600"/>
    <dbReference type="OMA" id="MKCYWAG"/>
    <dbReference type="OrthoDB" id="193380at2759"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00457"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004516">
        <property type="term" value="F:nicotinate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034355">
        <property type="term" value="P:NAD+ biosynthetic process via the salvage pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01570">
        <property type="entry name" value="NAPRTase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.140.10">
        <property type="entry name" value="nicotinate phosphoribosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041619">
        <property type="entry name" value="NAPRTase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040727">
        <property type="entry name" value="NAPRTase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007229">
        <property type="entry name" value="Nic_PRibTrfase-Fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006405">
        <property type="entry name" value="Nic_PRibTrfase_pncB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036068">
        <property type="entry name" value="Nicotinate_pribotase-like_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01513">
        <property type="entry name" value="NAPRTase_put"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11098">
        <property type="entry name" value="NICOTINATE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11098:SF1">
        <property type="entry name" value="NICOTINATE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17956">
        <property type="entry name" value="NAPRTase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17767">
        <property type="entry name" value="NAPRTase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51690">
        <property type="entry name" value="Nicotinate/Quinolinate PRTase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54675">
        <property type="entry name" value="Nicotinate/Quinolinate PRTase N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nicotinate phosphoribosyltransferase N-terminal" evidence="11">
        <location>
            <begin position="274"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="Nicotinate phosphoribosyltransferase C-terminal" evidence="12">
        <location>
            <begin position="667"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="72"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF17956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG93868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="791" mass="92259" checksum="593B67AA003E9A8D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNE6</accession>
    <name>A0A1J1GNE6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00150600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526619.1">
        <property type="nucleotide sequence ID" value="XM_028675049.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730030"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00150600"/>
    <dbReference type="OMA" id="MRIENVI"/>
    <dbReference type="OrthoDB" id="378565at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1392" mass="166318" checksum="C326BBD5B214EE40" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNH8</accession>
    <name>A0A1J1GNH8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00171700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526831.1">
        <property type="nucleotide sequence ID" value="XM_028670039.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNH8"/>
    <dbReference type="GeneID" id="39730244"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00171700"/>
    <dbReference type="OMA" id="ICFHGEL"/>
    <dbReference type="OrthoDB" id="354648at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="51" mass="6079" checksum="4F1315704D63FA8D" modified="2017-02-15" version="1">MFYPGMFREKPKDLLSDKWKIILRVSGFLVSCYLICYHGELFDIPEHNKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNN8</accession>
    <name>A0A1J1GNN8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Aminomethyltransferase</fullName>
            <ecNumber evidence="2 7">2.1.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 7">Glycine cleavage system T protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">GCVT</name>
        <name evidence="10" type="ORF">PGAL8A_00172000</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The glycine cleavage system catalyzes the degradation of glycine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>N(6)-[(R)-S(8)-aminomethyldihydrolipoyl]-L-lysyl-[protein] + (6S)-5,6,7,8-tetrahydrofolate = N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16945"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10492"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="2.1.2.10"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the GcvT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.10" evidence="2 7"/>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526834.1">
        <property type="nucleotide sequence ID" value="XM_028670042.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNN8"/>
    <dbReference type="GeneID" id="39730247"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00172000"/>
    <dbReference type="OMA" id="MPVQYPA"/>
    <dbReference type="OrthoDB" id="10263536at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005960">
        <property type="term" value="C:glycine cleavage complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004047">
        <property type="term" value="F:aminomethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006546">
        <property type="term" value="P:glycine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.110">
        <property type="entry name" value="Aminomethyltransferase beta-barrel domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1400">
        <property type="entry name" value="Aminomethyltransferase beta-barrel domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1250.10">
        <property type="entry name" value="Aminomethyltransferase fragment"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="entry name" value="Probable tRNA modification gtpase trme, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006223">
        <property type="entry name" value="GcvT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028896">
        <property type="entry name" value="GcvT/YgfZ/DmdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029043">
        <property type="entry name" value="GcvT/YgfZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013977">
        <property type="entry name" value="GcvT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006222">
        <property type="entry name" value="GCVT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00528">
        <property type="entry name" value="gcvT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43757">
        <property type="entry name" value="AMINOMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43757:SF2">
        <property type="entry name" value="AMINOMETHYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01571">
        <property type="entry name" value="GCV_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08669">
        <property type="entry name" value="GCV_T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006487">
        <property type="entry name" value="GcvT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101790">
        <property type="entry name" value="Aminomethyltransferase beta-barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103025">
        <property type="entry name" value="Folate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="GCVT N-terminal" evidence="8">
        <location>
            <begin position="31"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="Aminomethyltransferase C-terminal" evidence="9">
        <location>
            <begin position="312"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG94013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="398" mass="46079" checksum="A4333B5C06873F15" modified="2017-02-15" version="1">MKIFQNKNKLLLFRYFSSINKKKEEILKTILYDVHKKNNAIFKIHHGYYIPDEYKNDTLITTHLHTRSSCSLFDFTYRPILKISGKDKMCFLEKYVGSDIKGLWENECRISLLLNEKGGILDDIMIILRENYLLIYLNIQCKNKVYKYLNEQLIENTKLDVKIEEYKEHSSICIQGSKSTNVLNEISKDLNLENFSFMSSNLVKLNNIDNCLLNRYTCTGEDGFDILIPSKHVKELYESILNNHLVKPGGLAVQNTLRLESGFCIYGKDINENFTPIESNYKWIFGKRRLKELNFNGANIINDQIKNGTKIKRVGLTINSNIVPKENSKIYSHNNSNEEIGFITSSVFSPLLQKPIAMGYVKTEQSIINNNIKVNVLNKLENAQITKMPFVPLSIYKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP18</accession>
    <name>A0A1J1GP18_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cysteine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Cysteinyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PGAL8A_00391400</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.16" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527031.1">
        <property type="nucleotide sequence ID" value="XM_028670261.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP18"/>
    <dbReference type="GeneID" id="39732444"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00391400"/>
    <dbReference type="OMA" id="YEGLGWA"/>
    <dbReference type="OrthoDB" id="438179at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004817">
        <property type="term" value="F:cysteine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006423">
        <property type="term" value="P:cysteinyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00672">
        <property type="entry name" value="CysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000027">
        <property type="entry name" value="Cysteine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1910">
        <property type="entry name" value="Cysteine-tRNA ligase, C-terminal anti-codon recognition domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00041">
        <property type="entry name" value="Cys_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015803">
        <property type="entry name" value="Cys-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024909">
        <property type="entry name" value="Cys-tRNA/MSH_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032678">
        <property type="entry name" value="tRNA-synt_1_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00435">
        <property type="entry name" value="cysS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890:SF3">
        <property type="entry name" value="CYSTEINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890">
        <property type="entry name" value="CYSTEINYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01406">
        <property type="entry name" value="tRNA-synt_1e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00983">
        <property type="entry name" value="TRNASYNTHCYS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA synthetases class I catalytic" evidence="13">
        <location>
            <begin position="38"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="567"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="487"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG94210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="590" mass="69828" checksum="BE3D247A06E8352A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPE2</accession>
    <name>A0A1J1GPE2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00401000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527127.1">
        <property type="nucleotide sequence ID" value="XM_028670368.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732540"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00401000"/>
    <dbReference type="OMA" id="RGYIIIN"/>
    <dbReference type="OrthoDB" id="377452at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="813"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="821"/>
            <end position="830"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1592" mass="195197" checksum="F2AE2890B80D7049" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPI4</accession>
    <name>A0A1J1GPI4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Small GTP-binding protein sar1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">SAR1</name>
        <name evidence="16" type="ORF">PGAL8A_00090300</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the small GTPase superfamily. SAR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526021.1">
        <property type="nucleotide sequence ID" value="XM_028671588.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPI4"/>
    <dbReference type="GeneID" id="39729427"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00090300"/>
    <dbReference type="OMA" id="DCADYER"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00879">
        <property type="entry name" value="Sar1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001150">
        <property type="entry name" value="Small GTP-binding protein sar1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006687">
        <property type="entry name" value="Small_GTPase_SAR1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45684">
        <property type="entry name" value="RE74312P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51422">
        <property type="entry name" value="SAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 15" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 15" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="9 15" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10 13" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 15" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 15" id="KW-0813">Transport</keyword>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="27"/>
            <end position="34"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="129"/>
            <end position="132"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR606687-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR606687-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="CRG93199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="192" mass="21908" checksum="2A1F11869DE4F67B" modified="2017-02-15" version="1">MFIISWFKDILAHLGLSQKSARILFLGLDNAGKTTLLHMLKDDRVAQHVPTLHPHSEELVVGKIRFKTFDLGGHETARRIWKDYFAAVDAVVFMIDTTDRSRFNEAREELKQLLETEELSNVPFVILGNKIDKPDAASEDELRQHLNLFSNMTMGNNVKGNSGVRPVELFMCSVIRRMGYAAAFKWISQFLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPJ1</accession>
    <name>A0A1J1GPJ1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Exonuclease 1</fullName>
            <ecNumber evidence="9">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00181700</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">5'-&gt;3' double-stranded DNA exonuclease which may also possess a cryptic 3'-&gt;5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="9">Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="9"/>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527246.1">
        <property type="nucleotide sequence ID" value="XM_028670500.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPJ1"/>
    <dbReference type="GeneID" id="39730344"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00181700"/>
    <dbReference type="OMA" id="THNKGGD"/>
    <dbReference type="OrthoDB" id="26491at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035312">
        <property type="term" value="F:5'-3' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09901">
        <property type="entry name" value="H3TH_FEN1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09857">
        <property type="entry name" value="PIN_EXO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1010:FF:000002">
        <property type="entry name" value="Exonuclease 1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044752">
        <property type="entry name" value="PIN-like_EXO1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006086">
        <property type="entry name" value="XPG-I_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006085">
        <property type="entry name" value="XPG_DNA_repair_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081:SF8">
        <property type="entry name" value="EXONUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081">
        <property type="entry name" value="FLAP ENDONUCLEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00867">
        <property type="entry name" value="XPG_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00752">
        <property type="entry name" value="XPG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00853">
        <property type="entry name" value="XPGRADSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00484">
        <property type="entry name" value="XPGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00485">
        <property type="entry name" value="XPGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0228">DNA excision</keyword>
    <keyword evidence="7 9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="9 13" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 9" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XPG N-terminal" evidence="12">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="XPG-I" evidence="11">
        <location>
            <begin position="142"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="407"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="782"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="407"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="420"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU910737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG94425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1122" mass="132841" checksum="64518365413C9418" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPJ9</accession>
    <name>A0A1J1GPJ9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type 2A phosphatase-associated protein 42, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">TAP42</name>
        <name evidence="3" type="ORF">PGAL8A_00182500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527254.1">
        <property type="nucleotide sequence ID" value="XM_028670508.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPJ9"/>
    <dbReference type="GeneID" id="39730352"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00182500"/>
    <dbReference type="OMA" id="EYELCEA"/>
    <dbReference type="OrthoDB" id="10261753at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051721">
        <property type="term" value="F:protein phosphatase 2A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035303">
        <property type="term" value="P:regulation of dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009966">
        <property type="term" value="P:regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.540">
        <property type="entry name" value="TAP42-like family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038511">
        <property type="entry name" value="TAP42/TAP46-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007304">
        <property type="entry name" value="TAP46-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10933">
        <property type="entry name" value="IMMUNOGLOBULIN-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10933:SF9">
        <property type="entry name" value="IMMUNOGLOBULIN-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04177">
        <property type="entry name" value="TAP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="223"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="372" mass="45305" checksum="7A472C6D9DC12C9E" modified="2017-02-15" version="1">MEINEVISLFDHFYILFDDYIVKNTKDINSYNSIFNKKEFLEFLKFYSNVKIKNKEIISNKDEIIDELIYAFKHLGKYINRCDIFSKNEEIDDINTKYLKLLLIPYILGFLSYETININIRYDRLKDSKLYFHEYINLMNIYKIIKMDDYLFDEENSTNLVNRRNIKIKRTKDEKKYQEMFEEIFKNNLKYKDGNNIDDTCDDYREMYISLIKCKFIQTLNIIDLIDTELQFLEIRNNEKEDKKENVKNSDIKDQVRKPWFFSIKKKMQLSDVTQIRNYYKDLVFKPFHNLPTISLDECAKIEMEFSLKGTNDNNQKNNENDDIQDLKNDKNDDYYKEYSKKEREKEIFDKEWDDWKDLHQKGIGNKNRNIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPM3</accession>
    <name>A0A1J1GPM3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">V-type proton ATPase proteolipid subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00066600</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Vacuole membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the V-ATPase proteolipid subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG92962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525784.1">
        <property type="nucleotide sequence ID" value="XM_028675000.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPM3"/>
    <dbReference type="GeneID" id="39729191"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00066600"/>
    <dbReference type="OMA" id="KPPYAFF"/>
    <dbReference type="OrthoDB" id="433895at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033179">
        <property type="term" value="C:proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18175">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6C_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18176">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6C_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.610:FF:000001">
        <property type="entry name" value="V-type proton ATPase proteolipid subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.610">
        <property type="entry name" value="lithium bound rotor ring of v- atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000245">
        <property type="entry name" value="ATPase_proteolipid_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011555">
        <property type="entry name" value="ATPase_proteolipid_su_C_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01100">
        <property type="entry name" value="V_ATP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10263">
        <property type="entry name" value="V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00122">
        <property type="entry name" value="VACATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="F1F0 ATP synthase subunit C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <keyword evidence="9" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="85"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="124"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="10">
        <location>
            <begin position="14"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="10">
        <location>
            <begin position="92"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG92962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="164" mass="17071" checksum="7A1D3C521973292A" modified="2017-02-15" version="1">MRTCDPNSAFFGYMGIAASSIFSNLGAAFGTAKSGVGVCSVGVMRPDLVMKSILPVIMSGVLGIYGIIMSILIKGRISIDTYSTYLGYAHLSSGLIVGLSSLAAGLAIGIVGDAGVRANAQQNRLFMGLILILIFSEALALYGLIIGIYITMSDTPALCESYIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPS6</accession>
    <name>A0A1J1GPS6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Kinetochore protein NUF2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">NUF2</name>
        <name evidence="11" type="ORF">PGAL8A_00399800</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
            <location evidence="1">Centromere</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NUF2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527115.1">
        <property type="nucleotide sequence ID" value="XM_028670354.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPS6"/>
    <dbReference type="GeneID" id="39732528"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00399800"/>
    <dbReference type="OMA" id="YLKMEAH"/>
    <dbReference type="OrthoDB" id="8194677at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031262">
        <property type="term" value="C:Ndc80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.60">
        <property type="entry name" value="Ncd80 complex, Nuf2 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005549">
        <property type="entry name" value="Kinetochore_Nuf2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038275">
        <property type="entry name" value="Nuf2_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03800">
        <property type="entry name" value="Nuf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="8" id="KW-0137">Centromere</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinetochore protein Nuf2 N-terminal" evidence="10">
        <location>
            <begin position="7"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="139"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="311"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG94294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="457" mass="53664" checksum="6B03676F45AD509E" modified="2017-02-15" version="1">MNIGNEIVPKYGFEEMKNEISKYGVEITQSTLKNPTTEDVQGVYSICIKYILNKDINNIRIEEFTGDLKSSMPSIDGIQILPNEGKNHLQAIGNLRFIRHCEKINKILNLDNILSYIFKPVSSHITKLISAFIHFMKYKEEIYNENDAKIKKIQEKKNEDNILESELKTVDSELNMLLGRHDEVKTSIINEKSTKRNYEEEIIENQNLLNAQQSIIISLKSTKDKIINETNELIFQFSRLRQKKEDLEDQIVPSPEKLQQYNEELKDLLSEHMSYFESDKKKNEEIKSKINVADLSIKKLVDLLTILTNHVENTIKQHIDKKNELKNLEKNLKSLKIEKENLENKKEEQDNILSNTEQCFEEEKNKWNKKIHEEEKKITQVEKNVKTIYENIDNINFKTNREIKEINNIVKHIHDTINSYSRNCDIITDLIENTRNSQKILSDKVQNNIQKYIKANV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPU2</accession>
    <name>A0A1J1GPU2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10 11">Tubulin alpha chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PGAL8A_00192500</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 11">Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="2 11">Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the tubulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000029">
        <property type="protein sequence ID" value="CRG94527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527342.1">
        <property type="nucleotide sequence ID" value="XM_028670606.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPU2"/>
    <dbReference type="GeneID" id="39730450"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00192500"/>
    <dbReference type="OMA" id="YMASCIL"/>
    <dbReference type="OrthoDB" id="6049624at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02186">
        <property type="entry name" value="alpha_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.600:FF:000005">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.20:FF:000001">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000004">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002452">
        <property type="entry name" value="Alpha_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01162">
        <property type="entry name" value="ALPHATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11" id="KW-0493">Microtubule</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="12">
        <location>
            <begin position="49"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="13">
        <location>
            <begin position="248"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00071544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG94527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="450" mass="49719" checksum="61F4F19592642B3D" modified="2017-02-15" version="1">MREVISIHVGQAGIQIGNACWELFCLEHGIQPDGQMPSDQVVAGGDDAFNTFFSETGAGKHVPRCVFVDLEPTVVDEVRTGTYRQLFHPEQLISGKEDAANNFARGHYTIGKEIVDICLDRVRKLADNCTGLQGFLMFNAVGGGTGSGLGCLLLERLAIDYGKKSKLNFCSWPSPQVSTAVVEPYNSVLSTHSLLEHTDVAIMLDNEAIYDICKKNLDIERPTYTNLNRLIAQVISSLTASLRFDGALNVDVTEFQTNLVPYPRIHFMLSSYAPIISAEKAYHEQLSVSEITNSAFEPASMMAKCDPRHGKYMACCLMYRGDVVPKDVNAAVATIKTKRSIQFVDWCPTGFKCGINYQPPTVVPGGDLAKVMRAVCMISNSTAIAEVFSRMDQKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGIESNEGEGEDEGYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPX9</accession>
    <name>A0A1J1GPX9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00406000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527177.1">
        <property type="nucleotide sequence ID" value="XM_028670424.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732590"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00406000"/>
    <dbReference type="OMA" id="TITCMIN"/>
    <dbReference type="OrthoDB" id="361914at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="257"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="447"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="850"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="933"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="257"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="371"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="447"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="468"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="480"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="850"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="938"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="956"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="977"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="997"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1067"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1097"/>
            <end position="1109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1314" mass="151278" checksum="97FE7E7D8EFBDBE7" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ32</accession>
    <name>A0A1J1GQ32_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Gamma-tubulin complex component</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00202800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TUBGCP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527446.1">
        <property type="nucleotide sequence ID" value="XM_028670722.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730554"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00202800"/>
    <dbReference type="OMA" id="SYKSPIE"/>
    <dbReference type="OrthoDB" id="78652at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000930">
        <property type="term" value="C:gamma-tubulin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043015">
        <property type="term" value="F:gamma-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051011">
        <property type="term" value="F:microtubule minus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051225">
        <property type="term" value="P:spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1900">
        <property type="entry name" value="Gamma-tubulin complex, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007259">
        <property type="entry name" value="GCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040457">
        <property type="entry name" value="GCP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042241">
        <property type="entry name" value="GCP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041470">
        <property type="entry name" value="GCP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302:SF27">
        <property type="entry name" value="GAMMA-TUBULIN COMPLEX COMPONENT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04130">
        <property type="entry name" value="GCP_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17681">
        <property type="entry name" value="GCP_N_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma tubulin complex component protein N-terminal" evidence="9">
        <location>
            <begin position="174"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="Gamma tubulin complex component C-terminal" evidence="8">
        <location>
            <begin position="1112"/>
            <end position="1372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="103"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="432"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="854"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="114"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="439"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG94631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1742" mass="206484" checksum="D5771FB6A3B3DDCA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ99</accession>
    <name>A0A1J1GQ99_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Leucine carboxyl methyltransferase 1</fullName>
            <ecNumber evidence="6">2.1.1.233</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00198900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>[phosphatase 2A protein]-C-terminal L-leucine + S-adenosyl-L-methionine = [phosphatase 2A protein]-C-terminal L-leucine methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:48544"/>
            <dbReference type="Rhea" id="RHEA-COMP:12134"/>
            <dbReference type="Rhea" id="RHEA-COMP:12135"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90516"/>
            <dbReference type="ChEBI" id="CHEBI:90517"/>
            <dbReference type="EC" id="2.1.1.233"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the methyltransferase superfamily. LCMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.233" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527407.1">
        <property type="nucleotide sequence ID" value="XM_028670679.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ99"/>
    <dbReference type="GeneID" id="39730516"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00198900"/>
    <dbReference type="OMA" id="IIYEPIR"/>
    <dbReference type="OrthoDB" id="203237at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018423">
        <property type="term" value="F:protein C-terminal leucine carboxyl O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016651">
        <property type="entry name" value="LCMT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007213">
        <property type="entry name" value="Ppm1/Ppm2/Tcmp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13600">
        <property type="entry name" value="LEUCINE CARBOXYL METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13600:SF21">
        <property type="entry name" value="LEUCINE CARBOXYL METHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04072">
        <property type="entry name" value="LCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016305">
        <property type="entry name" value="LCM_mtfrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="154"/>
            <end position="155"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR016305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR016305-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="328" mass="39378" checksum="A76C3FD7284A5D14" modified="2017-02-15" version="1">MSIMNSSKTKVQKTTYEAASSKLSAVQLGYYYDPFLKYFVKKIEKRSPLINRGYYSRVVALRQYIELFMKSLDNTNYIQIVNIGAGLDTTFFWLSERYKNVKYYEIDFNEILSEKTRIINDVTLLKNFLIYDENIEEEKKDFINCVNYKMLYSDLNDWNSFEKNLQNNSFDFNLPTLFICECVLIYLEIESSDILIKKLSELMKNTSCIIVYEQVNPNTAFGKIMIDNFCSRGISLKSIYKYNNLDLQLKRFKSLGWSNVYINDMNEIYDYHICNEEKKKIEKIEMFDEFEEWRLLQNHYFMLVAFNCYNDLNLKYLEDFFKKKKKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQA8</accession>
    <name>A0A1J1GQA8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00202400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527442.1">
        <property type="nucleotide sequence ID" value="XM_028670717.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQA8"/>
    <dbReference type="GeneID" id="39730550"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00202400"/>
    <dbReference type="OMA" id="ARYFIRI"/>
    <dbReference type="OrthoDB" id="433860at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="476"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="617" mass="73383" checksum="8851FC3A91FA8C71" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQF1</accession>
    <name>A0A1J1GQF1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">RNA-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00213200</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527550.1">
        <property type="nucleotide sequence ID" value="XM_028670837.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQF1"/>
    <dbReference type="GeneID" id="39730659"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00213200"/>
    <dbReference type="OMA" id="IFCEYES"/>
    <dbReference type="OrthoDB" id="77405at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12374">
        <property type="entry name" value="RRM_UHM_SPF45_PUF60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000382">
        <property type="entry name" value="G-patch domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040052">
        <property type="entry name" value="RBM17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13288:SF8">
        <property type="entry name" value="SPLICING FACTOR 45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13288">
        <property type="entry name" value="SPLICING FACTOR 45 SPF45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="G-patch" evidence="10">
        <location>
            <begin position="363"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="9">
        <location>
            <begin position="439"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="285"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="216"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="69"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG94735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="533" mass="62315" checksum="6D6170E1A26F999A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQG7</accession>
    <name>A0A1J1GQG7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00208800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527506.1">
        <property type="nucleotide sequence ID" value="XM_028670789.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQG7"/>
    <dbReference type="GeneID" id="39730615"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00208800"/>
    <dbReference type="OMA" id="HHQKNRY"/>
    <dbReference type="OrthoDB" id="341115at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="24"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="147"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="435" mass="51367" checksum="EA401B32FEE62103" modified="2017-02-15" version="1">MASSTLKNVKVPEKKAAIKNLKIDINNNEEYKKLKEDKKKLKKELSIKETEINNLKKILEDKENDIKLNYIPLKEARKITFKALRKGSAAQKFISLIESNSINYKLKKKAINILLTNAYGVLHHQKNRYSDVLKYTDSHLKLFRQEQLILLAENERLTMQMKELKKQLLDNKIENIKKNEKNLITPMKRNTESIEKKNNNTDDNFVELDADIVEKNFINLIKNIKIAQLKLLFFAFRKLSNNVYNNVDPTNVSANMINSLKHGMDILNNILKNKKTVITCNAFYKLLNCNINNLLYKSKYLQKINKYSSCNYSNPKNGQRISHFVYKPYYYDNLPSATCDVQKKRLPILNDKKDLFMKDLIHKGEPLYEPFTYENVRNNISKNKYYKKDYFDMEVKKNFDSEKYSCFNDFDFLSDFSAYDKEKFIDLFITETTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQI4</accession>
    <name>A0A1J1GQI4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">snRNA-activating protein complex subunit 3, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00220200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNAPC3/SRD2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527620.1">
        <property type="nucleotide sequence ID" value="XM_028670915.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQI4"/>
    <dbReference type="GeneID" id="39730729"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00220200"/>
    <dbReference type="OMA" id="CCHKNIA"/>
    <dbReference type="OrthoDB" id="46583at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019185">
        <property type="term" value="C:snRNA-activating protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003681">
        <property type="term" value="F:bent DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001046">
        <property type="term" value="F:core promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001006">
        <property type="term" value="F:RNA polymerase III type 3 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042795">
        <property type="term" value="P:snRNA transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042796">
        <property type="term" value="P:snRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022042">
        <property type="entry name" value="snRNA-activating_su3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13421">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13421:SF16">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12251">
        <property type="entry name" value="SNAPC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG94805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="597" mass="71447" checksum="74C2966564D5E01E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQL8</accession>
    <name>A0A1J1GQL8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00104400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526160.1">
        <property type="nucleotide sequence ID" value="XM_028673132.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729569"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00104400"/>
    <dbReference type="OMA" id="IPIANDI"/>
    <dbReference type="OrthoDB" id="431154at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="251"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="384"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="795"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="859"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="887"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1173"/>
            <end position="1192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1596"/>
            <end position="1729"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="711"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="251"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="289"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="392"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="403"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="803"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="861"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="893"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1599"/>
            <end position="1727"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2066" mass="240107" checksum="1A3AC4D843DE8D95" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQS4</accession>
    <name>A0A1J1GQS4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MORN repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00220800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527626.1">
        <property type="nucleotide sequence ID" value="XM_028670922.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQS4"/>
    <dbReference type="GeneID" id="39730735"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00220800"/>
    <dbReference type="OMA" id="GYYKWNN"/>
    <dbReference type="OrthoDB" id="203073at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43215">
        <property type="entry name" value="RADIAL SPOKE HEAD 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43215:SF14">
        <property type="entry name" value="RADIAL SPOKE HEAD 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="332" mass="37951" checksum="A9185ACC35F2C165" modified="2017-02-15" version="1">MSCCSKNSIKVEIPEKKTLEHTQNDSNIKSDNHDDIPVSTVTLNDGSVYTGTTLDDKLHGRGILRYANGDIYEGEFVEGKKEGKGIWSDKEGNSYDGFWKNDKKHGEGIYKTHDGLIFEGCFNNNKKQGKGTITTPEKTKYICTFEDDVEKGEAEFFFSNGDHAWGYIKDGNLEGNGRYEFKNGDLYVGNFKNGLFHGKGYYKWNNNSSYQIYEGDYIEGKKHGNGQIINVDGRILRGKFVNNNLHGEILEISPQGNQVRVLFDNGKYVKIIDKIKEKLNVKEIMEESVINTTIFSNPECYKKIYEIEQRNKAKLRIQIKKSKDKKESLPRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQX2</accession>
    <name>A0A1J1GQX2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Diacylglycerol kinase</fullName>
            <shortName evidence="6">DAG kinase</shortName>
            <ecNumber evidence="6">2.7.1.107</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00230900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 1,2-diacyl-sn-glycerol + ATP = a 1,2-diacyl-sn-glycero-3-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10272"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.107"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the eukaryotic diacylglycerol kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.107" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527726.1">
        <property type="nucleotide sequence ID" value="XM_028671033.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQX2"/>
    <dbReference type="GeneID" id="39730836"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00230900"/>
    <dbReference type="OMA" id="IEKHDYW"/>
    <dbReference type="OrthoDB" id="242257at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004143">
        <property type="term" value="F:ATP-dependent diacylglycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007200">
        <property type="term" value="P:phospholipase C-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037607">
        <property type="entry name" value="DGK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000756">
        <property type="entry name" value="Diacylglycerol_kin_accessory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11255">
        <property type="entry name" value="DIACYLGLYCEROL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11255:SF121">
        <property type="entry name" value="DIACYLGLYCEROL KINASE (ATP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00609">
        <property type="entry name" value="DAGK_acc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00045">
        <property type="entry name" value="DAGKa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00046">
        <property type="entry name" value="DAGKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAGKc" evidence="7">
        <location>
            <begin position="172"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="498" mass="57650" checksum="7E4477FBCD36678C" modified="2017-02-15" version="1">MKYIFLFVNPTSGGNKASIFTEFGVNEIIFHKPHKCHFFIYNILEGEKGKKPGFLNLRSITNNPRKFESKAFSSFSKSKSFTDKNNLSLENKDSLIKRKYLSKEKIPTNSNRDSNDKNIDLDKHNEHECEKNKELVNETKCNELNCESKSDRKENELLSKRSNENKDISIYVLVAGGDGTLNWVLKESESYNINNNKFAVGVIPFGTGNDFARAFGWKKIDGIFNHSFLFNILKKIVDQTFKSKIEKHDYWNIEVVLKKDGYFNKINSKTKKKETLKENNENITELKLCMSNYFSIGIDSRIGRGFERHRKKNALCNKIVYAVEGFKKISFKKNIPVNLIIDKMVAGENYDNVIFTTNNSEVYPLLKKSMSIICINIPSYSSGNDIWNYTHKIGLNLPKNLTSDEKKVYDELKKSQQEVGDGILEFVIYQSGIDLGLEFTLKGRAYRVHQGIGPWKIFFKEQKYNVYFQVDGEYYLMSLPNYISICHYKKINVLKNIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR22</accession>
    <name>A0A1J1GR22_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Myosin E, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00142500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526541.1">
        <property type="nucleotide sequence ID" value="XM_028674962.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729949"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00142500"/>
    <dbReference type="OMA" id="NITHVHT"/>
    <dbReference type="OrthoDB" id="370884at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000146">
        <property type="term" value="F:microfilament motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.240.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140">
        <property type="entry name" value="MYOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140:SF270">
        <property type="entry name" value="MYOSIN-12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00193">
        <property type="entry name" value="MYOSINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0505">Motor protein</keyword>
    <keyword evidence="3 6" id="KW-0518">Myosin</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myosin motor" evidence="8">
        <location>
            <begin position="76"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="region of interest" description="Actin-binding" evidence="6">
        <location>
            <begin position="678"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="362"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1476" mass="175321" checksum="02046AFDD9322698" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRC3</accession>
    <name>A0A1J1GRC3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Poly(A) polymerase</fullName>
            <ecNumber evidence="11">2.7.7.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">PGAL8A_00154100</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Polymerase that creates the 3'-poly(A) tail of mRNA's.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>RNA(n) + ATP = RNA(n)-3'-adenine ribonucleotide + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:11332"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17347"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="ChEBI" id="CHEBI:173115"/>
            <dbReference type="EC" id="2.7.7.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="13">Binds 2 magnesium ions. Also active with manganese.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the poly(A) polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.19" evidence="11"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526653.1">
        <property type="nucleotide sequence ID" value="XM_028675086.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRC3"/>
    <dbReference type="GeneID" id="39730065"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00154100"/>
    <dbReference type="OMA" id="PAYPAMC"/>
    <dbReference type="OrthoDB" id="412748at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05402">
        <property type="entry name" value="NT_PAP_TUTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.460.10:FF:000027">
        <property type="entry name" value="Poly(A) polymerase PAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1410.10:FF:000001">
        <property type="entry name" value="Putative poly(A) polymerase gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.590">
        <property type="entry name" value="Poly(A) polymerase predicted RNA binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011068">
        <property type="entry name" value="NuclTrfase_I-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007012">
        <property type="entry name" value="PolA_pol_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048840">
        <property type="entry name" value="PolA_pol_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007010">
        <property type="entry name" value="PolA_pol_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014492">
        <property type="entry name" value="PolyA_polymerase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10682">
        <property type="entry name" value="POLY A POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10682:SF10">
        <property type="entry name" value="POLYNUCLEOTIDE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04928">
        <property type="entry name" value="PAP_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20750">
        <property type="entry name" value="PAP_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04926">
        <property type="entry name" value="PAP_RNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018425">
        <property type="entry name" value="PolyA_polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55003">
        <property type="entry name" value="PAP/Archaeal CCA-adding enzyme, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 11" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7 11 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Poly(A) polymerase nucleotidyltransferase" evidence="17">
        <location>
            <begin position="82"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Poly(A) polymerase central" evidence="16">
        <location>
            <begin position="282"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="Poly(A) polymerase RNA-binding" evidence="15">
        <location>
            <begin position="455"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="586"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="595"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="622"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="161"/>
            <end position="163"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="174"/>
            <end position="176"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="299"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR018425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR018425-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR018425-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF20750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="CRG93832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="633" mass="74703" checksum="0E71303128E40B09" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRE2</accession>
    <name>A0A1J1GRE2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein mL49</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00250500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL49 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527916.1">
        <property type="nucleotide sequence ID" value="XM_028671245.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRE2"/>
    <dbReference type="GeneID" id="39731033"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00250500"/>
    <dbReference type="OMA" id="IEKTDCW"/>
    <dbReference type="OrthoDB" id="19439at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.780.10">
        <property type="entry name" value="SUI1-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007740">
        <property type="entry name" value="Ribosomal_mL49"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036877">
        <property type="entry name" value="SUI1_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13477:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13477">
        <property type="entry name" value="MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05046">
        <property type="entry name" value="Img2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55159">
        <property type="entry name" value="eIF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 7" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="108" mass="13117" checksum="A3DA7CF45F429E5E" modified="2017-02-15" version="1">MSIFKFIYMPKYYLSIYNEYLNAYRKKINRIPFYIRRTASDNLPVFLKYKNRKNLVVTVIRKIKGNKEVLKKEIESICNSNVIEKPDCFLIKGNHKKKIKDYFKYIGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRN8</accession>
    <name>A0A1J1GRN8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lsm12, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00140400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526520.1">
        <property type="nucleotide sequence ID" value="XM_028674939.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRN8"/>
    <dbReference type="GeneID" id="39729928"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00140400"/>
    <dbReference type="OMA" id="FEGELYC"/>
    <dbReference type="OrthoDB" id="1057137at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047574">
        <property type="entry name" value="AD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039683">
        <property type="entry name" value="Lsm12-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019181">
        <property type="entry name" value="LSM12_ABD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13542">
        <property type="entry name" value="LSM12 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09793">
        <property type="entry name" value="AD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00995">
        <property type="entry name" value="AD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52001">
        <property type="entry name" value="AD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AD" evidence="1">
        <location>
            <begin position="78"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS52001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="178" mass="20650" checksum="0C664FF1D2FADBBC" modified="2017-02-15" version="1">MVKKIFDPSLYFGHTIVTRTSDGHTFEGELYCYDTSSNFIIIKEDNKNGTANFYIIRTNIITDVETKRRVKTLYEPLPIIDKNIVEKIERKAIINFEKNKSRIGIGVTQEAQELFDFIWKTHPDCVWNSKDILVLNGEVSIKPPYGPDNCIAKNEKLKERFATVISKFRQKKNLSNKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRR3</accession>
    <name>A0A1J1GRR3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Thioredoxin 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00256200</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. As part of the translocon PTEX complex, plays a role in the export of parasite proteins into the host erythrocyte. The translocon PTEX complex is a multi-protein machinery resident in the parasite parasitophorous vacuolar membrane, responsible for protein secretion into host cells. May contribute to the unfolding of proteins containing the PEXEL localization motif before their passage through the translocon or regulate the PTEX complex function.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527970.1">
        <property type="nucleotide sequence ID" value="XM_028671304.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRR3"/>
    <dbReference type="GeneID" id="39731090"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00256200"/>
    <dbReference type="OMA" id="CHACKMQ"/>
    <dbReference type="OrthoDB" id="2121326at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000405">
        <property type="entry name" value="Thioredoxin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45663">
        <property type="entry name" value="GEO12009P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45663:SF11">
        <property type="entry name" value="GEO12009P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012227306" description="Thioredoxin 2" evidence="9">
        <location>
            <begin position="24"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="10">
        <location>
            <begin position="27"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00056092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00069140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG95157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="156" mass="18504" checksum="61147AA731825E9B" modified="2017-02-15" version="1">MKFTILLSFFFFINFLYFVDVECTKSISFINEDPLTPLNKYDKYHLRLFKRVARLENVKNSLNGLSTKNKVIILYFYAKWCPACSMQSGEMDKLEKFYGKQINLFRINLDEYKKLAKKYSVVYLPTIIIMKNNVVLARKDHYTSSSDLINLIKKHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRW7</accession>
    <name>A0A1J1GRW7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Golgi organization and biogenesis factor, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00001600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat PRL1/PRL2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528062.1">
        <property type="nucleotide sequence ID" value="XM_028671406.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRW7"/>
    <dbReference type="GeneID" id="39728538"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00001600"/>
    <dbReference type="OMA" id="NGKCRIA"/>
    <dbReference type="OrthoDB" id="10256122at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000347">
        <property type="entry name" value="Pre-mRNA-splicing factor PRP46, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045241">
        <property type="entry name" value="Prp46/PLRG1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19923:SF0">
        <property type="entry name" value="PLEIOTROPIC REGULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19923">
        <property type="entry name" value="WD40 REPEAT PROTEINPRL1/PRL2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="277"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="319"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="361"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="403"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="151"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="152"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="595" mass="69203" checksum="C059E9C4A7E1C86A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRY6</accession>
    <name>A0A1J1GRY6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="7">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">BCKDH-E2</name>
        <name evidence="10" type="ORF">PGAL8A_00003000</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528076.1">
        <property type="nucleotide sequence ID" value="XM_028671423.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRY6"/>
    <dbReference type="GeneID" id="39728552"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00003000"/>
    <dbReference type="OMA" id="TPIFMEA"/>
    <dbReference type="OrthoDB" id="202158at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016407">
        <property type="term" value="F:acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031405">
        <property type="term" value="F:lipoic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.559.10:FF:000007">
        <property type="entry name" value="Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="entry name" value="E3-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050743">
        <property type="entry name" value="2-oxoacid_DH_E2_comp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43178">
        <property type="entry name" value="DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43178:SF5">
        <property type="entry name" value="LIPOAMIDE ACYLTRANSFERASE COMPONENT OF BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE COMPLEX, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4 7" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="9">
        <location>
            <begin position="34"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="115"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="115"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="144"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG95265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="471" mass="53509" checksum="A82F0E4C8BCE4D9E" modified="2017-02-15" version="1">MITKNIKNIFSRINLITNKNKVCYINTSALNFKVVKCKLFDIGEGISEVEITQWNKNEGDQVNEMESLLTVQSDKASVDITSKYSGVLIKKYANEKDLIKVGSYFCEIDTEDGVVEEKENNEEKTKSEENEDEDEDENKIRLEEDLDDQSDELNLENPSNISNTNTFEREQEQKIFVKASPGVKKKAKEYNLDINTISKYFNKQTITMDDVENYYNSRNNVEKVDNNSVDILEEVPLKGIKLAMCKSMNDSLSIPLFHLNEMCMVENLLKIKNEFKKILHEKENINITITCIIIKLISIALNDFPILNSKFDSKKNSYTIYKNHNVCVAMDTPNGLLVPNIKNVEKKNIIDIQKDLTLLRDKAINMKLSKSDISDGTVTISNFGAISGSFATPIVFDNQACIIGVSKVQRQLFLKNEKNELNSLNDIMVSDTVNLTYGADHRFIDGATLAQFSKKLKGLIENPISIIPFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSC9</accession>
    <name>A0A1J1GSC9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ADP-ribosylation factor, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00166300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526776.1">
        <property type="nucleotide sequence ID" value="XM_028669979.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSC9"/>
    <dbReference type="GeneID" id="39730189"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00166300"/>
    <dbReference type="OMA" id="LYVINIM"/>
    <dbReference type="OrthoDB" id="414781at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="204" mass="23906" checksum="0B0D634089421A04" modified="2017-02-15" version="1">MGNTVNKKVNSAIEENRINNKKKSGKKYNILILGLNGSGKTTLLYHNFIPEWTNITSYMEPTISYHYEEIKWINGTIGFWDISGNPIMRNIWKLIYRNVKVNAILYVINIMDISDESTTENNMLISLLMNDECLQASCVVLVFNTFNNVNIIDDTFKNELLIKYKIKDLINDYGNRIHYIFVDCKNCNLDKNWMDLIKQISYYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GST2</accession>
    <name>A0A1J1GST2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Plasmodium RESA N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00273400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528346.1">
        <property type="nucleotide sequence ID" value="XM_028671722.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GST2"/>
    <dbReference type="GeneID" id="39731266"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00273400"/>
    <dbReference type="OMA" id="HILHIFY"/>
    <dbReference type="OrthoDB" id="10449038at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="262" mass="31704" checksum="E8E3D7FFAF8C1E38" modified="2017-02-15" version="1">MLLMFTFFLIMKKFKVLFFFSYLLIVNLLIPCLTSEPENYHNIPNVPLESNSHLVRTHSNSDSFVIPTKFVDLTYDLLHHILHIFYNSINVERQEMIKGIKSILHLVHNFLNSRKEELSKCSIRLMTKFTSNELRRIHNKTPAEKGIEKDCLKEHMNYWSKIKFDYNNMIEKMHQQWQSGGKSKNKSSKWKKVKWEEWHNYFHKYLIREGKRSRLDFVCMMQNGCNYTNVKYHYEKIISLWDEDMKSMWTKWNSFLDNALKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT31</accession>
    <name>A0A1J1GT31_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00279600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528407.1">
        <property type="nucleotide sequence ID" value="XM_028671790.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT31"/>
    <dbReference type="GeneID" id="39731329"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00279600"/>
    <dbReference type="OMA" id="FFSWGTM"/>
    <dbReference type="OrthoDB" id="373682at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="406" mass="46790" checksum="270BC8C9EC802904" modified="2017-02-15" version="1">MEGENAQNSIKPFQAINSTEHFEEPQNYNLIKKAKIFTSTHYFDGTSWTALEKPLNLKKTIFDDERILTLDPVEENSIPVELEASLGGKYDIKVYRKSDVILCIEGEEKILIKMPITKNIITWNSSQRLPVLPKIWRPTVFILNEGNIFVRMIPDKCLVISKVNKSDSFKVECINFSEGFCCCHPINNLALLYGDYEQNQEFSVMKLPKLPVSNGKYNYFIHFFSWGTMIVPKYAEISKGLLCNLKPNVIALLIVPPKIHISIELDSYSPVACSLDYKKDFLITARKPNITDIEIYLIAHDQLIKYEYSFDLRLNKDNAPISYLHVPIKFKISKEEKEKKKKDPSYKCKWSFIDIKDQKVLSPSSNSSSYHIMSSDLACIFDAETGTYYSTEYGIHYCKAFKKLQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT99</accession>
    <name>A0A1J1GT99_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutamic acid-rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00294500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528548.1">
        <property type="nucleotide sequence ID" value="XM_028671946.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT99"/>
    <dbReference type="GeneID" id="39731478"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00294500"/>
    <dbReference type="OrthoDB" id="272750at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1740.10">
        <property type="entry name" value="VC0467-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003774">
        <property type="entry name" value="AlgH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30327">
        <property type="entry name" value="UNCHARACTERIZED PROTEIN YQGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30327:SF1">
        <property type="entry name" value="UPF0301 PROTEIN YQGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143456">
        <property type="entry name" value="VC0467-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="619"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="811"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="154"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="619"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="650"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="811"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="835"/>
            <end position="847"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="972" mass="115946" checksum="988F83EF956A2BC3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTK7</accession>
    <name>A0A1J1GTK7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Surface-related antigen SRA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00303000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528626.1">
        <property type="nucleotide sequence ID" value="XM_028672033.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTK7"/>
    <dbReference type="GeneID" id="39731563"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00303000"/>
    <dbReference type="OrthoDB" id="372890at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="341"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="613"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="354"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="386"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="399"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="613"/>
            <end position="629"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="821" mass="96212" checksum="F62B79E976B2BDEB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTM1</accession>
    <name>A0A1J1GTM1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Diphthamide synthesis protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00301100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DPH1/DPH2 family. DPH2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528607.1">
        <property type="nucleotide sequence ID" value="XM_028672012.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTM1"/>
    <dbReference type="GeneID" id="39731544"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00301100"/>
    <dbReference type="OMA" id="IEMYILL"/>
    <dbReference type="OrthoDB" id="361972at2759"/>
    <dbReference type="UniPathway" id="UPA00559"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090560">
        <property type="term" value="F:2-(3-amino-3-carboxypropyl)histidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11860:FF:000001">
        <property type="entry name" value="2-(3-amino-3-carboxypropyl)histidine synthase subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11840">
        <property type="entry name" value="Diphthamide synthesis DPH1/DPH2 domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11860">
        <property type="entry name" value="Diphthamide synthesis DPH1/DPH2 domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016435">
        <property type="entry name" value="DPH1/DPH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042263">
        <property type="entry name" value="DPH1/DPH2_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042265">
        <property type="entry name" value="DPH1/DPH2_3"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00322">
        <property type="entry name" value="diphth2_R"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10762:SF2">
        <property type="entry name" value="2-(3-AMINO-3-CARBOXYPROPYL)HISTIDINE SYNTHASE SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10762">
        <property type="entry name" value="DIPHTHAMIDE BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01866">
        <property type="entry name" value="Diphthamide_syn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00032">
        <property type="entry name" value="Radical_SAM_3-amino-3-carboxyp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="615" mass="73373" checksum="712AD101D80F2B76" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTU9</accession>
    <name>A0A1J1GTU9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sm protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00286400</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the snRNP SmB/SmN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528475.1">
        <property type="nucleotide sequence ID" value="XM_028671864.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTU9"/>
    <dbReference type="GeneID" id="39731397"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00286400"/>
    <dbReference type="OMA" id="KMINYRM"/>
    <dbReference type="OrthoDB" id="2020720at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005687">
        <property type="term" value="C:U4 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070990">
        <property type="term" value="F:snRNP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01717">
        <property type="entry name" value="Sm_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050914">
        <property type="entry name" value="snRNP_SmB/NAA38-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10701:SF0">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10701">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Sm" evidence="12">
        <location>
            <begin position="2"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="173"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="173"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="183"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG95667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="252" mass="28263" checksum="A2B41864C95316DE" modified="2017-02-15" version="1">MGKNSRLETWLHYRVRVTVSDTRYFVGTFLSYDRHMNIVLVDAEEFRKIKDQETGFKEIKRVVGLILIRGENIVSFTAEQGPINKKSMNNVINKGIATGRGIPLSNYVPLQNNFNTNLTNPISNMPTGMALNSSTTKNLTPAVNPNFRSPNAPLNNSRPMIPMNIPINQPISNANNMQQRLPPQMPPQMPPQMPPQIPPQMPPQMPPQIPPQIPPQMPPQMPPQMPPQVPPQMPPQVPPQLPFPPSMKPPTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTV4</accession>
    <name>A0A1J1GTV4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Eukaryotic translation initiation factor 5, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00315300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF-2-beta/eIF-5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528748.1">
        <property type="nucleotide sequence ID" value="XM_028672168.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTV4"/>
    <dbReference type="GeneID" id="39731686"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00315300"/>
    <dbReference type="OMA" id="YRYKMEK"/>
    <dbReference type="OrthoDB" id="10250831at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071074">
        <property type="term" value="F:eukaryotic initiation factor eIF2 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005092">
        <property type="term" value="F:GDP-dissociation inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.170:FF:000002">
        <property type="entry name" value="Eukaryotic translation initiation factor 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045196">
        <property type="entry name" value="IF2/IF5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002735">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016189">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016190">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003307">
        <property type="entry name" value="W2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23001">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23001:SF7">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01873">
        <property type="entry name" value="eIF-5_eIF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02020">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00653">
        <property type="entry name" value="eIF2B_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100966">
        <property type="entry name" value="Translation initiation factor 2 beta, aIF2beta, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75689">
        <property type="entry name" value="Zinc-binding domain of translation initiation factor 2 beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51363">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 8" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="W2" evidence="7">
        <location>
            <begin position="227"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="152"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="206"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="482" mass="55735" checksum="D1A9ED3F156B0675" modified="2017-02-15" version="1">MSYINIPRDRNDPNYRYKMPKLISKIEGRGNGIRTNIANMGEIARSLKRPPMYPTKFFGCELGTMVKFEENEEKAIVNGAHKEKDLVNILDKFIEMYVLCPHCLLPETDIIVKKGFLICKCNACGNIGELNNSHKIATYMIKNPPLISTVGNKKKKIKEKKVEKNGKNKNEKIEKNEENKNGINSGADIEGSEEIDTDKSNQNTKKEKKNKKKDKKKKAEDNFVLEKEALNFESPEIKEVIDRLRSLFEANPKISDNTFSEELRVLQVSQCFDSKCRIFICLCSLFDDKITKELLEKNIRYLKKINDTSVTIKDIFLALEYYVNKIAVNSIHIYPYILQVLYNNDIFESKDIIKRYDENDNEIQDQVNEDDYVNKFYIECYSKCKNMAKPFVSWLKENDSDTESEEENVNNNVVKNNIINYKVKSLGNNEGKSNKENNNCSNENDKVFEDSKSEKCDDEIFLDAKDGINYTGDEEEIDIDAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU54</accession>
    <name>A0A1J1GU54_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fam-f protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00320400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528799.1">
        <property type="nucleotide sequence ID" value="XM_028672226.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU54"/>
    <dbReference type="GeneID" id="39731737"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00320400"/>
    <dbReference type="OMA" id="GHNIELY"/>
    <dbReference type="OrthoDB" id="10592091at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="403"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="617" mass="73606" checksum="E361C487A51C778A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUD7</accession>
    <name>A0A1J1GUD7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphodiesterase</fullName>
            <ecNumber evidence="6">3.1.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00312600</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="6">Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cyclic nucleotide phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.-" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528721.1">
        <property type="nucleotide sequence ID" value="XM_028672138.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUD7"/>
    <dbReference type="GeneID" id="39731659"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00312600"/>
    <dbReference type="OMA" id="IFITCKK"/>
    <dbReference type="OrthoDB" id="546632at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004114">
        <property type="term" value="F:3',5'-cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1300.10">
        <property type="entry name" value="3'5'-cyclic nucleotide phosphodiesterase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023088">
        <property type="entry name" value="PDEase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002073">
        <property type="entry name" value="PDEase_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036971">
        <property type="entry name" value="PDEase_catalytic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023174">
        <property type="entry name" value="PDEase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11347">
        <property type="entry name" value="CYCLIC NUCLEOTIDE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00233">
        <property type="entry name" value="PDEase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00387">
        <property type="entry name" value="PDIESTERASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00126">
        <property type="entry name" value="PDEASE_I_1"/>
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    </dbReference>
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        <property type="entry name" value="PDEASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="244"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="279"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="323"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="347"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="378"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="PDEase" evidence="9">
        <location>
            <begin position="513"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="436"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="609"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="609"/>
            <end position="613"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="613"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="649"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="650"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="650"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="650"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
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        <location>
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        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
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    <feature type="binding site" evidence="5">
        <location>
            <position position="761"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
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        <location>
            <position position="813"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
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            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR623088-1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR623088-2"/>
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    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR623088-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
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            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG95913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="883" mass="106520" checksum="6420561724B53551" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUD9</accession>
    <name>A0A1J1GUD9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00307100</name>
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    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
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            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
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    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_028672078.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731604"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00307100"/>
    <dbReference type="OMA" id="LKNKWEN"/>
    <dbReference type="OrthoDB" id="371567at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="783"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1250"/>
            <end position="1284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="CRG95859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1650" mass="194270" checksum="30294BA478F3D9BA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUN3</accession>
    <name>A0A1J1GUN3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Asparagine-rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00215000</name>
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    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
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        <lineage>
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            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="protein sequence ID" value="CRG94753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00215000"/>
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    <dbReference type="Proteomes" id="UP000220797">
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            <end position="346"/>
        </location>
    </feature>
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        <location>
            <begin position="854"/>
            <end position="894"/>
        </location>
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            <begin position="918"/>
            <end position="943"/>
        </location>
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        <location>
            <begin position="973"/>
            <end position="1039"/>
        </location>
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        <location>
            <begin position="325"/>
            <end position="346"/>
        </location>
    </feature>
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        <location>
            <begin position="854"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="879"/>
            <end position="890"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1071" mass="125770" checksum="DCE60F5A70D15BC1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUN8</accession>
    <name>A0A1J1GUN8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00323000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
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            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000049">
        <property type="protein sequence ID" value="CRG96017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528825.1">
        <property type="nucleotide sequence ID" value="XM_028672254.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUN8"/>
    <dbReference type="GeneID" id="39731763"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00323000"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012407674" evidence="2">
        <location>
            <begin position="28"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="216"/>
        </location>
    </feature>
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        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
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            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="389" mass="46698" checksum="632A942463EA5C54" modified="2017-02-15" version="1">MKTLILFLKITTLLLIWMYQCFYNCDSYKTLIDKNRLQIRNELKYERVLTEGDIAGGNQTYVEGCQEECPVEKKKKEKKRKNWFFPLLHHNAYDQWQRGITEGLFEQFKNVTSEMDPKWRDQKWNNEWNEISANKFNEASSIFHRSDISKDEKKKLILGVKNELFILFVKFLEECKKEMKKNKTESESKKEMIDNKTDSESKKEMRDNKTDSESMKEITYNKTESESMKETINNKTDSESKKEIIDHKTDSESMKEMIDNRTDSESKKEMIYNKTESESMKEMINNKTDSESKKEIIDHKTDSESMKEMIDNRTESEFKNEMRDNISESESMKEMRENRTESETMNEMRGNKRESESMKEQGKNKIKNEKSNIWKFLFNRFDNLWENEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUP4</accession>
    <name>A0A1J1GUP4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Insulinase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00344900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529036.1">
        <property type="nucleotide sequence ID" value="XM_028672489.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731979"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00344900"/>
    <dbReference type="OMA" id="WEGFARI"/>
    <dbReference type="OrthoDB" id="952271at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000015">
        <property type="entry name" value="Putative zinc metalloprotease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43016:SF16">
        <property type="entry name" value="METALLOPROTEASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G07610)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43016">
        <property type="entry name" value="PRESEQUENCE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M16 N-terminal" evidence="3">
        <location>
            <begin position="48"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="4">
        <location>
            <begin position="195"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1248"/>
            <end position="1313"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="844"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1262"/>
            <end position="1291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1313" mass="152497" checksum="65FAB895F174F045" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUQ1</accession>
    <name>A0A1J1GUQ1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C-CAP/cofactor C-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00318400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TBCC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528779.1">
        <property type="nucleotide sequence ID" value="XM_028672204.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUQ1"/>
    <dbReference type="GeneID" id="39731717"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00318400"/>
    <dbReference type="OMA" id="AFPLKCK"/>
    <dbReference type="OrthoDB" id="427777at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017901">
        <property type="entry name" value="C-CAP_CF_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016098">
        <property type="entry name" value="CAP/MinC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039589">
        <property type="entry name" value="TBCC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012945">
        <property type="entry name" value="Tubulin-bd_cofactor_C_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16052">
        <property type="entry name" value="TBCC DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16052:SF0">
        <property type="entry name" value="TBCC DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07986">
        <property type="entry name" value="TBCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51329">
        <property type="entry name" value="C_CAP_COFACTOR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C-CAP/cofactor C-like" evidence="2">
        <location>
            <begin position="414"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="788" mass="93659" checksum="43286E6E7CFC3939" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUZ6</accession>
    <name>A0A1J1GUZ6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00327500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000054">
        <property type="protein sequence ID" value="CRG96059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528867.1">
        <property type="nucleotide sequence ID" value="XM_028672301.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUZ6"/>
    <dbReference type="GeneID" id="39731805"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00327500"/>
    <dbReference type="OMA" id="THTYTWN"/>
    <dbReference type="OrthoDB" id="348930at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="561"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="331"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="387"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="415"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="437"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="453"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="485"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="561"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="580"/>
            <end position="602"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="635" mass="70330" checksum="5308AD5A9C4BD4C6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV42</accession>
    <name>A0A1J1GV42_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Heat shock protein 70, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00361500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529196.1">
        <property type="nucleotide sequence ID" value="XM_028672667.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV42"/>
    <dbReference type="GeneID" id="39732145"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00361500"/>
    <dbReference type="OMA" id="KHIRMPF"/>
    <dbReference type="OrthoDB" id="2401965at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11733">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.34.10:FF:000014">
        <property type="entry name" value="Chaperone protein DnaK HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.10:FF:000001">
        <property type="entry name" value="Molecular chaperone DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000004">
        <property type="entry name" value="Molecular chaperone DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000003">
        <property type="entry name" value="Molecular chaperone DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00332">
        <property type="entry name" value="DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012725">
        <property type="entry name" value="Chaperone_DnaK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001413">
        <property type="entry name" value="PRK00290.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02350">
        <property type="entry name" value="prok_dnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="632"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="286"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="541"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="636"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="649"/>
            <end position="662"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="662" mass="73282" checksum="26D41BB7ADB5FB16" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV53</accession>
    <name>A0A1J1GV53_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SNARE protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00338200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528969.1">
        <property type="nucleotide sequence ID" value="XM_028672414.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV53"/>
    <dbReference type="GeneID" id="39731912"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00338200"/>
    <dbReference type="OMA" id="ENVIWER"/>
    <dbReference type="OrthoDB" id="158360at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="283" mass="33478" checksum="839A5E14AF1D5E7D" modified="2017-02-15" version="1">MSYKYEELLDNEFINSTNKNENNNIENDIYSNISLNNIYTKIVKIRKELEKSYNLFYSYNLVVSNQKQENDNLYNNHSNLYKRNDSMNQNKNTKNNITLSKINALTNSFFVNVETLKNTYSFINANNLNNKIINNENVIWEKRIETLSKESNSYIKTLDNIYKNNLKQSEKNNKTNIYKNTKKKNINDTISYLHNEKEILKQVENNLNIFQVQGMNALSMIRKQNKFLKNVRKKVIDMYNYVGLSSSLIDAIKKAHKQNLIIVIVGIILSLIFFYVLYSYFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV56</accession>
    <name>A0A1J1GV56_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatidylinositol-4-phosphate 5-kinase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00356400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529151.1">
        <property type="nucleotide sequence ID" value="XM_028672616.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV56"/>
    <dbReference type="GeneID" id="39732094"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00356400"/>
    <dbReference type="OMA" id="HNNYNIH"/>
    <dbReference type="OrthoDB" id="423343at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23084:SF179">
        <property type="entry name" value="OS10G0565000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23084">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="688"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="892"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1056"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="692"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="702"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="713"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="729"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="780"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="892"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1075"/>
            <end position="1094"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1094" mass="130261" checksum="CA381333C1950C43" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVD0</accession>
    <name>A0A1J1GVD0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00239200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527808.1">
        <property type="nucleotide sequence ID" value="XM_028671125.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVD0"/>
    <dbReference type="GeneID" id="39730920"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00239200"/>
    <dbReference type="OMA" id="YMNVELY"/>
    <dbReference type="OrthoDB" id="392774at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36593">
        <property type="entry name" value="EXPORTED SERINE/THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36593:SF1">
        <property type="entry name" value="EXPORTED SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="807"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="857"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="889"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="926"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="225"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="520"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="108"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="228"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="529"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="990" mass="119541" checksum="3764F166B552D640" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVM9</accession>
    <name>A0A1J1GVM9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cilia- and flagella-associated protein 251</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00418100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529404.1">
        <property type="nucleotide sequence ID" value="XM_028672897.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVM9"/>
    <dbReference type="GeneID" id="39732712"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00418100"/>
    <dbReference type="OMA" id="NYEENTT"/>
    <dbReference type="OrthoDB" id="4899631at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031514">
        <property type="term" value="C:motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050630">
        <property type="entry name" value="WD_repeat_EMAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720:SF13">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 251"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720">
        <property type="entry name" value="WD-40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00040994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1151" mass="136919" checksum="DC9F8125C542FF28" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVN5</accession>
    <name>A0A1J1GVN5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00375500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529335.1">
        <property type="nucleotide sequence ID" value="XM_028672820.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVN5"/>
    <dbReference type="GeneID" id="39732285"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00375500"/>
    <dbReference type="OMA" id="TINEMDS"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3030.10">
        <property type="entry name" value="Gametocyte protein Pfg27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036469">
        <property type="entry name" value="Pfg27_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89162">
        <property type="entry name" value="Gametocyte protein Pfg27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="420" mass="48991" checksum="F66A6EF345D60E06" modified="2017-02-15" version="1">MNIIIKKIYDLYLLFSTIKMNISKKLIFNLLLIFNLIGFLFNDNFSSSSLNNVLLVRNHELREIKRNLAEMIPSTSSEYEKKSNDGAEFGPRRFIDVYVQAEADAFLELLDTLRSNYEKKDETINEMDSLLRSINSRFSSEGIKLSFDGLMDVHKRVAERAMFYVSNSTPQMFDLLRNIIQIESQICIEILQTIINEDKIIDEEIVKYNEVISALQGKIEESNLSLIDVKLKSIALRIHDFIECAVSVYNSRFANAVVKNENYVNGYIGIEKIAMDNIFNYICNVCGRKCTEVYHNPKFVLNTIYELYLKNNLTLSFEQVENIYTRIRKRITYLSKKRLTKKLILHIDVSYSVEFELAKLYTFQALQSTSDENEQKKVENVDKIRRMTEEKLRSHRSQIEGREIGRMAGRIQQIVFDIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVP7</accession>
    <name>A0A1J1GVP7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00375800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000060">
        <property type="protein sequence ID" value="CRG96533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529338.1">
        <property type="nucleotide sequence ID" value="XM_028672824.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVP7"/>
    <dbReference type="GeneID" id="39732288"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00375800"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="247" mass="28653" checksum="50B756534CA00414" modified="2017-02-15" version="1" fragment="single">KHFSIITEYNALSYKYPSKTYLCRLRKISQKATICEHIDASYLGKTLSFNSYDVINGKDNIINIKRSKNSKHTVTKLKYRDLSFGRNTCHIVKTKYIEENKCMYHLCEVVNGHLSCFNAYYSGRLIFIDDILYSAIEKRKFLYLPGSCLTKDSNFICDPQLCQYNSTQKLTSCEKLEISSIKNIIPSRGTLEPAPTYMPISHENRPSTSILLATSFMPFLVMLVFIWCFVYKFLRSRKSKLFINISV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVT9</accession>
    <name>A0A1J1GVT9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00424400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529468.1">
        <property type="nucleotide sequence ID" value="XM_028672968.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVT9"/>
    <dbReference type="GeneID" id="39732776"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00424400"/>
    <dbReference type="OrthoDB" id="385031at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012136503" evidence="1">
        <location>
            <begin position="25"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="405" mass="48844" checksum="1820A8FAA2D0A489" modified="2017-02-15" version="1">MHIKNNKILFFYILLILIFNINFSENKLFDDITKCINYLSCNFMNKIKYTSCNTSIKNFNRFKYKDTNEDIIKKKNSNKNEIYLSKTSNHEKYKRKRMFKYFLRPIVNEYRIINNLYNRNIYLLNKIMIPLNMKYKNNHKCFLTKINHFVVGKISDDNVINNRNVFLKKTNQNGNNWSTSHLSALSDSIVSDNSIINENNYKCYDKSGMKEENRIPLIENNTHIQENDINECSLKEKKEKKGKKRILSEESKKSMREKLKSIMIEKWKNLEFRKKMISSFRKRGIEHNKKISEAVKNKWKYDENYKLKTLEGQRKYFIRRKNTSIKSTSEETKIKISKAMKQYWLNRNKCKKSEFNNLQSLIKKKKKHKKVWENIYSLILNQKSDDFSNYNTFHNLSINLQESLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVU5</accession>
    <name>A0A1J1GVU5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00360600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529187.1">
        <property type="nucleotide sequence ID" value="XM_028672657.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVU5"/>
    <dbReference type="GeneID" id="39732136"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00360600"/>
    <dbReference type="OMA" id="YRIYYIN"/>
    <dbReference type="OrthoDB" id="385467at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052824">
        <property type="entry name" value="m6A_RNA_Methylation_Regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13585">
        <property type="entry name" value="CHASCON, ISOFORM D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13585:SF19">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="968"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="259"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1126"/>
            <end position="1153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="270"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="381"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="393"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1158" mass="141717" checksum="72BC7E1C2C59EBDF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVV4</accession>
    <name>A0A1J1GVV4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Translation elongation factor P/YeiP central domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00426200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the elongation factor P family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529486.1">
        <property type="nucleotide sequence ID" value="XM_028672989.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVV4"/>
    <dbReference type="GeneID" id="39732794"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00426200"/>
    <dbReference type="OMA" id="KFACQAK"/>
    <dbReference type="OrthoDB" id="10259892at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020599">
        <property type="entry name" value="Transl_elong_fac_P/YeiP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013185">
        <property type="entry name" value="Transl_elong_KOW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001059">
        <property type="entry name" value="Transl_elong_P/YeiP_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30053">
        <property type="entry name" value="ELONGATION FACTOR P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30053:SF14">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR KOW-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01132">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08207">
        <property type="entry name" value="EFP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01185">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Translation elongation factor P/YeiP central" evidence="2">
        <location>
            <begin position="105"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="173" mass="20093" checksum="0D3CB1E23930B745" modified="2017-02-15" version="1">MKNMYKIMYSGQINNLFKRINNPINNNYFFNLKKYVSVLANELRSGNIFLHNDKYCEVTEQRQIKQGRLATTNMISYIDLSTLKSASTKFACQAKVEKIEPIKMNVKIQYTDKQKNIAVCLDDNYEDIEIPLNIFGISEEYLEPGLQVSVFKHEEKIIKVNLPSSLLATLRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVV7</accession>
    <name>A0A1J1GVV7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">3'-5' exonuclease, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00019500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528237.1">
        <property type="nucleotide sequence ID" value="XM_028671601.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVV7"/>
    <dbReference type="GeneID" id="39728717"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00019500"/>
    <dbReference type="OMA" id="ITHDCRE"/>
    <dbReference type="OrthoDB" id="368776at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46814">
        <property type="entry name" value="EGALITARIAN, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46814:SF1">
        <property type="entry name" value="EGALITARIAN, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00474">
        <property type="entry name" value="35EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3'-5' exonuclease" evidence="2">
        <location>
            <begin position="44"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="1">
        <location>
            <begin position="289"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="366" mass="43579" checksum="2B5877AA6E5C8734" modified="2017-02-15" version="1">MYRFFNNHINKIFKRKITNISYGYLNLSIHDKIIHYFENLKKNIIYINDSKNCKEYINEIKKNLNEKYNFIGLDVEGYKIGKHGIISIIQICTENIYIFDLYKCDNTYLFIMYLKEILENEKIIKITHDCREDCSILYNQYNINLNNVFDTQVAYNLFLKKKKKDLYQISYDDLLFKCLLLNNNHKIYFHKIISLDPKVYLKRPISKELIQYAIQDVLYLKPLMLILIDKLNNIDEKKNILLDLNEEKKKVYNLDLHKIDLINYVIDNSQKYINYQFLNSHIKNEKKLQKGMIIEGMIVSCSNLKIYVKLNLSKKGVITNYLNHKYEIGDIVKCIILGFSGNNYINLGFSQSSNDKLNDLKIIKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVY9</accession>
    <name>A0A1J1GVY9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00429200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529516.1">
        <property type="nucleotide sequence ID" value="XM_028673022.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVY9"/>
    <dbReference type="GeneID" id="39732824"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00429200"/>
    <dbReference type="OMA" id="HAGFYIL"/>
    <dbReference type="OrthoDB" id="391305at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="281" mass="33719" checksum="2200CFAD2E40CCC4" modified="2017-02-15" version="1">MDPYKFNSWIRILISFCSSGVYILVSLMLPLFVAKFDFETRYGIFFIDPYNEKFLRWDEYESQICNKDEINPPNPKIPQHKSDLFCHSLSFFKKYFLIVFIVILINLIIVKSLLIYSHFREHPETFAVKHVKFCNKLIILIACLSLINSALIIIPAFLFNKKKEFGEKHYLHPGFYILLSDFLSHLVVIIFLQRDKTILKCVCELELLPWEKKQKLPVYNVDFNDTLISPNEITNYLQRIFHEDNINEEQLKNYFKTDNYEEIYYIIMNNIKIQNEMMNRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWE8</accession>
    <name>A0A1J1GWE8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">aspartyl aminopeptidase</fullName>
            <ecNumber evidence="4">3.4.11.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">M18AAP</name>
        <name evidence="12" type="ORF">PGAL8A_00445400</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal aspartate or glutamate from a peptide, with a preference for aspartate.</text>
            <dbReference type="EC" id="3.4.11.21"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the peptidase M18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.21" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529676.1">
        <property type="nucleotide sequence ID" value="XM_028673200.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWE8"/>
    <dbReference type="GeneID" id="39732987"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00445400"/>
    <dbReference type="OMA" id="GPILKVN"/>
    <dbReference type="OrthoDB" id="9880441at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05658">
        <property type="entry name" value="M18_DAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000090">
        <property type="entry name" value="M18 aspartyl aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.250.10">
        <property type="entry name" value="Aminopeptidase i, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001948">
        <property type="entry name" value="Peptidase_M18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023358">
        <property type="entry name" value="Peptidase_M18_dom2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002759">
        <property type="entry name" value="PRK02813.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28570">
        <property type="entry name" value="ASPARTYL AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28570:SF3">
        <property type="entry name" value="ASPARTYL AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02127">
        <property type="entry name" value="Peptidase_M18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00932">
        <property type="entry name" value="AMINO1PTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101821">
        <property type="entry name" value="Aminopeptidase/glucanase lid domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11 12" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6 11" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG96873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="512" mass="58911" checksum="6646D5A690F953C3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWL8</accession>
    <name>A0A1J1GWL8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00429700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529521.1">
        <property type="nucleotide sequence ID" value="XM_028673027.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWL8"/>
    <dbReference type="GeneID" id="39732829"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00429700"/>
    <dbReference type="OrthoDB" id="374071at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="49" mass="5791" checksum="5058F89DE399E189" modified="2017-02-15" version="1">MFLLNNENEESPKDILLNELKYKIRILAGIIFVIRTVPMVLDLFNKKNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWN8</accession>
    <name>A0A1J1GWN8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Aspartate aminotransferase</fullName>
            <ecNumber evidence="8">2.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">AspAT</name>
        <name evidence="10" type="ORF">PGAL8A_00019800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:21824"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="EC" id="2.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3 8">Homodimer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="8">In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.1" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528240.1">
        <property type="nucleotide sequence ID" value="XM_028671604.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWN8"/>
    <dbReference type="GeneID" id="39728720"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00019800"/>
    <dbReference type="OMA" id="VGACTIV"/>
    <dbReference type="OrthoDB" id="6752799at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004069">
        <property type="term" value="F:L-aspartate:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000796">
        <property type="entry name" value="Asp_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879:SF22">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00799">
        <property type="entry name" value="TRANSAMINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 10" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="9">
        <location>
            <begin position="30"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG95429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="405" mass="47578" checksum="719963AA1A436FBC" modified="2017-02-15" version="1">MDNVLSKLKEFEPDSILTSTREFTKDKSEKKVNLSIGICCNEDGGLHVFKSVLEAEKLILEKNKEKPYLLSNGSKEFSILTQKLIFGENSEYMKEKRICTIQTIGGTGAIFIILEFLRGFNIESIYVTNIPYVNHVYMLKSFGFNVKYLNYFDPELIDINYELFLNDLRNIKNNSNILLQVCCYNPCSVDIEEKYFDEIADIVLKKNHLVIFDVAYQGLGNSDLGKDVLLIRKFQERKISFTVCQSFSKNMSLYGERAGALHIVCKNKTERQLLFNNLRMIIRRFYTSPIIHTNRIVCEVLKNEKLKSQWLKDLYELSERIKNNRFLFFDKLKYYQKKYNLNYDWDVYKKQKGIFSFIPIFGNIYMKLREYHIYIIDSGRINISGITKKNVDYIAEKICLCLSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX16</accession>
    <name>A0A1J1GX16_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SUMO-activating enzyme subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">UBA2</name>
        <name evidence="11" type="ORF">PGAL8A_00458700</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="4">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Heterodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the ubiquitin-activating E1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529810.1">
        <property type="nucleotide sequence ID" value="XM_028673349.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX16"/>
    <dbReference type="GeneID" id="39733120"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00458700"/>
    <dbReference type="OMA" id="TPSEHIH"/>
    <dbReference type="OrthoDB" id="10255449at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="UniPathway" id="UPA00886"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031510">
        <property type="term" value="C:SUMO activating enzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019948">
        <property type="term" value="F:SUMO activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2660">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, SCCH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028077">
        <property type="entry name" value="UAE_UbL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030661">
        <property type="entry name" value="Uba2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019572">
        <property type="entry name" value="UBA_E1_SCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042063">
        <property type="entry name" value="Ubi_acti_E1_SCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF5">
        <property type="entry name" value="SUMO-ACTIVATING ENZYME SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14732">
        <property type="entry name" value="UAE_UbL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10585">
        <property type="entry name" value="UBA_E1_SCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039133">
        <property type="entry name" value="SUMO_E1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="8">
        <location>
            <begin position="8"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-activating enzyme SCCH" evidence="9">
        <location>
            <begin position="283"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin/SUMO-activating enzyme ubiquitin-like" evidence="10">
        <location>
            <begin position="489"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="5">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="26"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="58"/>
            <end position="61"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="117"/>
            <end position="122"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="476"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="479"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR039133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR039133-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR039133-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR039133-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF10585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF14732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG97007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="648" mass="76215" checksum="DC0F2B7432C480AD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX66</accession>
    <name>A0A1J1GX66_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Vacuolar protein sorting-associated protein 16, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">VPS16</name>
        <name evidence="5" type="ORF">PGAL8A_00461600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the VPS16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529839.1">
        <property type="nucleotide sequence ID" value="XM_028673381.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX66"/>
    <dbReference type="GeneID" id="39733149"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00461600"/>
    <dbReference type="OMA" id="WCGDDCL"/>
    <dbReference type="OrthoDB" id="1792at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030897">
        <property type="term" value="C:HOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042144">
        <property type="term" value="P:vacuole fusion, non-autophagic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.780:FF:000003">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 16, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.780">
        <property type="entry name" value="Vps16, C-terminal region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016534">
        <property type="entry name" value="VPS16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006925">
        <property type="entry name" value="Vps16_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038132">
        <property type="entry name" value="Vps16_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006926">
        <property type="entry name" value="Vps16_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12811">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING VPS16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12811:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 16 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04840">
        <property type="entry name" value="Vps16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04841">
        <property type="entry name" value="Vps16_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007949">
        <property type="entry name" value="VPS16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vps16 N-terminal" evidence="4">
        <location>
            <begin position="2"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Vps16 N-terminal" evidence="4">
        <location>
            <begin position="302"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="Vps16 C-terminal" evidence="3">
        <location>
            <begin position="607"/>
            <end position="929"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR007949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="936" mass="109511" checksum="8CAC52C745E3B311" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX78</accession>
    <name>A0A1J1GX78_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00311400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528709.1">
        <property type="nucleotide sequence ID" value="XM_028672125.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX78"/>
    <dbReference type="GeneID" id="39731647"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00311400"/>
    <dbReference type="OMA" id="CRNKYKN"/>
    <dbReference type="OrthoDB" id="371757at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="426" mass="52150" checksum="7D85C814CA02B13B" modified="2017-02-15" version="1">MLRLQKINRINHIHLKLLNEEKNKINVCVNEYKQIIWNNNSKTCKNKYKNIDNLHNIIKSSVLKNYKNVYFYKNLLRIAENRKNDFNLHQINVIIKSLIKAKIYRYSLFHSFEVPILKYVRYLNTYINDMKNNNNLKYVDELYKKLKLNEERYKSNKKCNLYFLIISDQFNILIDIFKSYNYINFKYDYFYETLFFFLTKNYIYLNNRKDLSDIWIIYLNKVLCNDVTFLKNKNEFFNIKNIHNLMEKNSFNFFRLYRHKYKCNINMKTIYNYIITSKKKINKTEKKTSYNSIFCKNNIFSICKYLVIIILKDEKLIRYKNKKINKIKNLYISNGYMYKIRNSNKILTNLQVKYLIKINIVENLAFLKKNCFPKELLNNINFLQKLSNILSEFKIKSFLFNRYIKNVKKLEEVSKINNNFLIEQKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXB2</accession>
    <name>A0A1J1GXB2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">tRNA methyltransferase, putative</fullName>
            <ecNumber evidence="10">2.1.1.61</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00479000</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.61" evidence="10"/>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530014.1">
        <property type="nucleotide sequence ID" value="XM_028673575.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXB2"/>
    <dbReference type="GeneID" id="39733323"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00479000"/>
    <dbReference type="OMA" id="HYAMIST"/>
    <dbReference type="OrthoDB" id="3685at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004808">
        <property type="term" value="F:tRNA (5-methylaminomethyl-2-thiouridylate)(34)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046885">
        <property type="entry name" value="MnmA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051305">
        <property type="entry name" value="tRNA_2-thiouridylase_MnmA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43052">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43052:SF1">
        <property type="entry name" value="TRNA-5-TAURINOMETHYLURIDINE 2-SULFURTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03054">
        <property type="entry name" value="tRNA_Me_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20258">
        <property type="entry name" value="tRNA_Me_trans_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="2 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="1" id="KW-0820">tRNA-binding</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013198724" evidence="8">
        <location>
            <begin position="18"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-specific 2-thiouridylase MnmA-like C-terminal" evidence="9">
        <location>
            <begin position="683"/>
            <end position="756"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF20258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG97211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="815" mass="98055" checksum="D34014A3A420923A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY31</accession>
    <name>A0A1J1GY31_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00376500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000097">
        <property type="protein sequence ID" value="CRG97392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530194.1">
        <property type="nucleotide sequence ID" value="XM_028673775.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY31"/>
    <dbReference type="GeneID" id="39732295"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00376500"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="286"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="322" mass="38506" checksum="1817E3F1E99B1304" modified="2017-02-15" version="1">MALLYNEGCENFEEDSAICRMSICSIKQNKFEKSYCNLEDKLVKVYRPLNNASNDISRNIFKYERYGPYRYSRIIILSDNNQDGIVFLYEYNIYNDYYPTKTYLCRLRNINQTAALCESLDIYYLGIRLSFSSYDVISEKNDIPLKHLKKPNHKIIKSKYKDLFIKEHSCHHIKTRYISDHNCMYAICEKKNEDYMLCSDANYSGKLIFLHDMNLINRRFIYLPESCLKIDSNFACNSYFCEINAKDKFFPCEYKEISAIKNIMPNAKRLEVMPIRQQIVHHEKNFSASALSAMTLMPFLILFVFFWCYIYKHFKKKRRKIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY43</accession>
    <name>A0A1J1GY43_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">ADP-ribosylation factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">ARF1</name>
        <name evidence="18" type="ORF">PGAL8A_00480100</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.</text>
    </comment>
    <comment type="function">
        <text evidence="12">Small GTPase involved in protein trafficking between different compartments. Modulates vesicle budding and uncoating within the Golgi complex. In its GTP-bound form, triggers the recruitment of coatomer proteins to the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles. Regulates the transport of N-acylated AK2 to the parasitophorous vacuole membrane. May be involved in the activation of lipid kinase PIP5K.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="13">May interact with GTPase RAB5b.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530025.1">
        <property type="nucleotide sequence ID" value="XM_028673587.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY43"/>
    <dbReference type="SMR" id="A0A1J1GY43"/>
    <dbReference type="GeneID" id="39733334"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00480100"/>
    <dbReference type="OMA" id="HYYANTN"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003925">
        <property type="term" value="F:G protein activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04150">
        <property type="entry name" value="Arf1_5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000024">
        <property type="entry name" value="ADP-ribosylation factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045872">
        <property type="entry name" value="Arf1-5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 17" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 17" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 14 16" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10 17" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 17" id="KW-0519">Myristate</keyword>
    <keyword evidence="5 14 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 17" id="KW-0653">Protein transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 17" id="KW-0813">Transport</keyword>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="24"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="126"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00058055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00061917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU369003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="CRG97222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="181" mass="20912" checksum="18013B069BEA2413" modified="2017-02-15" version="1">MGLYVSRLFNRLFQKKDVRILMVGLDAAGKTTILYKVKLGEVVTTIPTIGFNVETVEFRNISFTVWDVGGQDKIRPLWRHYYSNTDGLIFVVDSNDRERIDDAREELHRMINEEELKDAIILVFANKQDLPNAMSAAEVTEKLHLNTIRERNWFIQSTCATRGDGLYEGFDWLTTHLNNAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY48</accession>
    <name>A0A1J1GY48_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">rRNA methyltransferase 2, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00505700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530285.1">
        <property type="nucleotide sequence ID" value="XM_028673876.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY48"/>
    <dbReference type="GeneID" id="39733590"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00505700"/>
    <dbReference type="OMA" id="HRQTDHL"/>
    <dbReference type="OrthoDB" id="20105at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008650">
        <property type="term" value="F:rRNA (uridine-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01547">
        <property type="entry name" value="RNA_methyltr_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050082">
        <property type="entry name" value="RNA_methyltr_RlmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002877">
        <property type="entry name" value="RNA_MeTrfase_FtsJ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015507">
        <property type="entry name" value="rRNA-MeTfrase_E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10920">
        <property type="entry name" value="RIBOSOMAL RNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10920:SF18">
        <property type="entry name" value="RRNA METHYLTRANSFERASE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01728">
        <property type="entry name" value="FtsJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005461">
        <property type="entry name" value="23S_rRNA_mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribosomal RNA methyltransferase FtsJ" evidence="8">
        <location>
            <begin position="60"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00041184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR005461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG97484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="260" mass="30350" checksum="7D944387601600B6" modified="2017-02-15" version="1">MRLIIQRINEKKNFLFQNNIIRLYREALPKVFNKKSNHSSKWIQRQITDRYVLKAKNENYRSRAAYKLIELDNKYLFLKKNKVILDIGCYPGSWCQVILERTKNYSNEIIAIDKKIMDPLPNVHFIKGEIGKDNIDNKLKELLKDKKADIILSDAAVACIGNKIDDHLNSCELTLSITNFMEKFINIGGTYIVKMYLGSQTNNLKTYLKTIFQFVNTAKPKASRSESREIYLVCRNFQGRKKISEDIQIKGAFSLKEGYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY68</accession>
    <name>A0A1J1GY68_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00478700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530011.1">
        <property type="nucleotide sequence ID" value="XM_028673572.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY68"/>
    <dbReference type="GeneID" id="39733320"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00478700"/>
    <dbReference type="OMA" id="ETNWNTS"/>
    <dbReference type="OrthoDB" id="5568754at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039720">
        <property type="entry name" value="TMEM94"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13219">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 94"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13219:SF6">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 94"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="271"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="304"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="955"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="986"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1028"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1128"/>
            <end position="1145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1165"/>
            <end position="1185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1197"/>
            <end position="1217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1246" mass="148238" checksum="4FEB1EA208DD3913" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY90</accession>
    <name>A0A1J1GY90_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00510300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530331.1">
        <property type="nucleotide sequence ID" value="XM_028673927.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY90"/>
    <dbReference type="GeneID" id="39733636"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00510300"/>
    <dbReference type="OrthoDB" id="372061at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="849"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="663"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="665"/>
            <end position="684"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1141" mass="136139" checksum="86AECE6E397A093B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYI6</accession>
    <name>A0A1J1GYI6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ubiquitin-like protein nedd8 homologue, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Nedd8</name>
        <name evidence="2" type="ORF">PGAL8A_00509300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530321.1">
        <property type="nucleotide sequence ID" value="XM_028673916.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYI6"/>
    <dbReference type="GeneID" id="39733626"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00509300"/>
    <dbReference type="OMA" id="YAGKQMA"/>
    <dbReference type="OrthoDB" id="1043111at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000226">
        <property type="entry name" value="Ubiquitin-like protein nedd8 homologue, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="78" mass="8912" checksum="92C0FC378BC12102" modified="2017-02-15" version="1">MQILVKTLTGKRQSFNFEPSSSVYQIKMAIEEKEGIDAKQIRLIYSGKQMHDDMKLSDYRVVPGSTIHMILQLRGGII</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYJ4</accession>
    <name>A0A1J1GYJ4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00510100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530329.1">
        <property type="nucleotide sequence ID" value="XM_028673925.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733634"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00510100"/>
    <dbReference type="OMA" id="FDICKLF"/>
    <dbReference type="OrthoDB" id="392808at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40201:SF1">
        <property type="entry name" value="AP-3 COMPLEX SUBUNIT DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40201">
        <property type="entry name" value="OSMIOPHILIC BODY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="879"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1078"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1185"/>
            <end position="1204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="630"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2540"/>
            <end position="2635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2656"/>
            <end position="2678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2544"/>
            <end position="2635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2656"/>
            <end position="2677"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3141" mass="376728" checksum="4C29AB5F1D9D3772" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYS0</accession>
    <name>A0A1J1GYS0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00367300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529253.1">
        <property type="nucleotide sequence ID" value="XM_028672729.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732203"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00367300"/>
    <dbReference type="OMA" id="KIFIFMH"/>
    <dbReference type="OrthoDB" id="10256906at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990071">
        <property type="term" value="C:TRAPPII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034498">
        <property type="term" value="P:early endosome to Golgi transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045126">
        <property type="entry name" value="TRAPPC10/Trs130"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13251">
        <property type="entry name" value="EPILEPSY HOLOPROSENCEPHALY CANDIDATE 1/TMEM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13251:SF3">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="506"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1885" mass="226607" checksum="3CFCE6C68342EBF9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYT3</accession>
    <name>A0A1J1GYT3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00530700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530531.1">
        <property type="nucleotide sequence ID" value="XM_028674149.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYT3"/>
    <dbReference type="GeneID" id="39733840"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00530700"/>
    <dbReference type="OrthoDB" id="386165at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="236"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="271" mass="32055" checksum="8F7CB8FA612E21BD" modified="2017-02-15" version="1">MIKFFRKNGVNSYFTQNINNCKIFKLNYKYSYNIKRKYVNIKVDGKKKKIHNEELNLNDDVRDIYFNSKLIEKKFADIKIKDSHNKLLFEFLPIEGRTYTVPLCFKIMHYIFLFIISSGVVLIHILPEIDKENYIRDILTLEIYFSSCFLAFNGGFNSLLQLIQYAIPPNRKYKGLYNSLRYISSLIPIFFSLISTSLCENFPRDSLFLLVLSYLTLLLNYYLLHIKCLIPVWVFKQYKVIISIIILNLLLLLISEAQLYKGRKISINVDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ21</accession>
    <name>A0A1J1GZ21_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00413400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000066">
        <property type="protein sequence ID" value="CRG96552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529357.1">
        <property type="nucleotide sequence ID" value="XM_028672845.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ21"/>
    <dbReference type="GeneID" id="39732664"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00413400"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006496">
        <property type="entry name" value="CHP01606_Plasmodium_spp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09688">
        <property type="entry name" value="Wx5_PLAF3D7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013176096" evidence="2">
        <location>
            <begin position="29"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="224" mass="27059" checksum="64B126955E2DDEAA" modified="2017-02-15" version="1">MKTLTLYFKITTFLLLIWMYQCFHNCDTYKTLIDKNILQTKNELKYERVLTEGDIAAKRQAYAEGCQKECSLDYEKNKWENLLLQENPYDRWQKVTNPNLFERFKKETSGMDPKWIDEKWNNEWNNISANKVSDLSSIFHRNDISEDEKEKLIFNVMEELSSLYLKFLDECKKEMRDNKSESESKIEMRENKTESECMNEQGKNKKKKKKSNILKFLFCRFDNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZA6</accession>
    <name>A0A1J1GZA6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cytochrome c2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00421300</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome c family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529437.1">
        <property type="nucleotide sequence ID" value="XM_028672934.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZA6"/>
    <dbReference type="GeneID" id="39732745"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00421300"/>
    <dbReference type="OMA" id="WNDINLM"/>
    <dbReference type="OrthoDB" id="449280at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="entry name" value="Cytochrome c-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002327">
        <property type="entry name" value="Cyt_c_1A/1B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11961">
        <property type="entry name" value="CYTOCHROME C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="Cytochrome c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4 8" id="KW-0349">Heme</keyword>
    <keyword evidence="7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cytochrome c" evidence="10">
        <location>
            <begin position="24"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG96633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="147" mass="17070" checksum="703054E83FF08C11" modified="2017-02-15" version="1">MSAAGRIKSYVDDSIADDFILPSGDCFRGYKLFKKYCQQCHSISKNNEINQGTSMIGPNLYGLYGRTAGLYENSLYKASDLLKNSGIVWNDINLMRYLQNPNRFIEGNIHMNFKGINNFQDKVDLIWFIKYMCHKDWISDTRDNEKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZM1</accession>
    <name>A0A1J1GZM1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cell traversal protein for ookinetes and, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00531200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530536.1">
        <property type="nucleotide sequence ID" value="XM_028674155.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZM1"/>
    <dbReference type="GeneID" id="39733845"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00531200"/>
    <dbReference type="OrthoDB" id="371698at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041004">
        <property type="entry name" value="CelTOS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18659">
        <property type="entry name" value="CelTOS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013244173" evidence="2">
        <location>
            <begin position="31"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Cell-traversal protein for ookinetes and sporozoites" evidence="3">
        <location>
            <begin position="39"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="197" mass="22048" checksum="37873BEBC5CBF917" modified="2017-02-15" version="1">MNQLKRLSIVSTFLLFFSLLNVSCFRGNNGTNVISSLQNESQIYDHLNNNISSFILQPQSLEKIGNDLADTIANEIVSALQNDSTSFLQEKVIFDIKGQIKRHAKEVLKEVAKAGIQPIEEVVASSVKPPTISPHAYQLLKPILKSLFNKVENSIKTDVPDTIWDYEGESSKENEEGEEEEEEDGFDELADSMINES</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H001</accession>
    <name>A0A1J1H001_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mitochondrial carrier protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00417700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529400.1">
        <property type="nucleotide sequence ID" value="XM_028672893.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H001"/>
    <dbReference type="GeneID" id="39732708"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00417700"/>
    <dbReference type="OrthoDB" id="43906at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015093">
        <property type="term" value="F:ferrous iron transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048250">
        <property type="term" value="P:iron import into the mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45758:SF4">
        <property type="entry name" value="MITOFERRIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45758">
        <property type="entry name" value="MITOFERRIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="675"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="942"/>
            <end position="1024"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG96596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1032" mass="122489" checksum="46DED98F5D4FCBD1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H014</accession>
    <name>A0A1J1H014_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Endoplasmin, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">GRP94</name>
        <name evidence="10" type="ORF">PGAL8A_00536400</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530586.1">
        <property type="nucleotide sequence ID" value="XM_028674211.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H014"/>
    <dbReference type="GeneID" id="39733897"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00536400"/>
    <dbReference type="OMA" id="QFGKHIR"/>
    <dbReference type="OrthoDB" id="28737at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16927">
        <property type="entry name" value="HATPase_Hsp90-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000005">
        <property type="entry name" value="Heat shock protein 90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.790">
        <property type="entry name" value="Heat shock protein 90, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00505">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019805">
        <property type="entry name" value="Heat_shock_protein_90_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037196">
        <property type="entry name" value="HSP90_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001404">
        <property type="entry name" value="Hsp90_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020575">
        <property type="entry name" value="Hsp90_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003555">
        <property type="entry name" value="PRK05218.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11528">
        <property type="entry name" value="HEAT SHOCK PROTEIN 90 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00183">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002583">
        <property type="entry name" value="Hsp90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00775">
        <property type="entry name" value="HEATSHOCK90"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110942">
        <property type="entry name" value="HSP90 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00298">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011977976" evidence="8">
        <location>
            <begin position="28"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase/HSP90-like ATPase" evidence="9">
        <location>
            <begin position="118"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="33"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="804"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="490"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="41"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="804"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="815"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="191"/>
            <end position="192"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="212"/>
            <end position="217"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="462"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR002583-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG97785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="860" mass="99673" checksum="15983CB2D3AD1C9B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H040</accession>
    <name>A0A1J1H040_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cullin, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00024500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cullin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530610.1">
        <property type="nucleotide sequence ID" value="XM_028674237.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728768"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00024500"/>
    <dbReference type="OMA" id="IVNMFEN"/>
    <dbReference type="OrthoDB" id="10431365at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045093">
        <property type="entry name" value="Cullin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016158">
        <property type="entry name" value="Cullin_homology"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036317">
        <property type="entry name" value="Cullin_homology_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11932">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00182">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75632">
        <property type="entry name" value="Cullin homology domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50069">
        <property type="entry name" value="CULLIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cullin family profile" evidence="2">
        <location>
            <begin position="1485"/>
            <end position="1707"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1838" mass="224978" checksum="C2D24D985399CEBF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0B2</accession>
    <name>A0A1J1H0B2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CG2-related protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00454200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529765.1">
        <property type="nucleotide sequence ID" value="XM_028673297.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0B2"/>
    <dbReference type="GeneID" id="39733075"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00454200"/>
    <dbReference type="OMA" id="CYDYFFY"/>
    <dbReference type="OrthoDB" id="6093641at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="455"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="662"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="703"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="domain" description="F-box" evidence="3">
        <location>
            <begin position="6"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="855" mass="102976" checksum="A95214C93E3B313F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0I0</accession>
    <name>A0A1J1H0I0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00437100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529592.1">
        <property type="nucleotide sequence ID" value="XM_028673106.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0I0"/>
    <dbReference type="GeneID" id="39732903"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00437100"/>
    <dbReference type="OMA" id="CIFHFLP"/>
    <dbReference type="OrthoDB" id="365359at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="733"/>
            <end position="760"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="923" mass="110471" checksum="1C4C1B71EBB4411E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0W0</accession>
    <name>A0A1J1H0W0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00474900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000093">
        <property type="protein sequence ID" value="CRG97170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529973.1">
        <property type="nucleotide sequence ID" value="XM_028673529.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0W0"/>
    <dbReference type="GeneID" id="39733282"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00474900"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="291" mass="34361" checksum="E26BED41F2968E82" modified="2017-02-15" version="1">MALLYNEGCENFEEDSAKCRMVICPIKQNKFEKSFCDLDKGLVKVYRPLNNASNDITRNIFKYERYVPYRSSRIIILSDNNQDGIVFLYEYNVHYDPYPTKTYLCRLRNINQKAAICESVDMYYLDKRLSFSSYDVISEKNDQPLKHLKNPNHKIIKSNYKNLFIKEHSCHHMKTKYISGRNCMYAICEKENEDYVLCSDANYSGKLIFLYSVDNGIYKKFIYLPERCLTRDSNLECVSYFCETYAKDKFFPCEHKEISAIKDIMPYSKRSEVMPIKQQIVHHEDNLSASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H131</accession>
    <name>A0A1J1H131_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00456100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529784.1">
        <property type="nucleotide sequence ID" value="XM_028673320.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H131"/>
    <dbReference type="GeneID" id="39733094"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00456100"/>
    <dbReference type="OMA" id="YELRYYY"/>
    <dbReference type="OrthoDB" id="377316at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="341" mass="40862" checksum="ADDB52F1CB3F6BB3" modified="2017-02-15" version="1">MITSIDVIHELLTTIYYNIFSRNKSNINKFDILLYLDDYYYFDILKKVSEDIKDLDNSSIIIEKGDFNIIFNNFCTSRNYIIKDKNYSNDNEKRIDFLHEILSDLLCLLYKNKITKKKRVISKIYNSEKNEKWKILENHLISIAKLNNKNILKVSENNIEDILDINNESFKNENIIIQKKVNKDIEKILNTLINKYNAEYKLRFYYMFLNYNLTIQTMLMSHLINLYSKEVKDIIKNIINIKNERYEPINIYDVLSFQFDQIKFNKSSHDNLITPVKKIKIMRDIVERGGIPAEFSKKAILKDVINANYSLKEKYNKNRNQNENFSGKKYKVRNYYDSSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1Q3</accession>
    <name>A0A1J1H1Q3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tripartite motif protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00504000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530268.1">
        <property type="nucleotide sequence ID" value="XM_028673857.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1Q3"/>
    <dbReference type="GeneID" id="39733573"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00504000"/>
    <dbReference type="OMA" id="IENIRCS"/>
    <dbReference type="OrthoDB" id="376097at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19804">
        <property type="entry name" value="Bbox1_TRIM19_C-V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000315">
        <property type="entry name" value="Znf_B-box"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57845">
        <property type="entry name" value="B-box zinc-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50119">
        <property type="entry name" value="ZF_BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="B box-type" evidence="3">
        <location>
            <begin position="187"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="370"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="697" mass="82592" checksum="17AF1DAFB6C08A46" modified="2017-02-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1Y9</accession>
    <name>A0A1J1H1Y9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00492100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530144.1">
        <property type="nucleotide sequence ID" value="XM_028673719.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1Y9"/>
    <dbReference type="GeneID" id="39733454"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00492100"/>
    <dbReference type="OMA" id="DMENQNN"/>
    <dbReference type="OrthoDB" id="361150at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="385"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="417"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="535"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="669" mass="77591" checksum="70BFF56CCE9194F3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H211</accession>
    <name>A0A1J1H211_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">U2 snRNA/tRNA pseudouridine synthase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00494500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pseudouridine synthase TruD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530168.1">
        <property type="nucleotide sequence ID" value="XM_028673746.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H211"/>
    <dbReference type="GeneID" id="39733478"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00494500"/>
    <dbReference type="OrthoDB" id="447290at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02576">
        <property type="entry name" value="PseudoU_synth_ScPUS7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.20">
        <property type="entry name" value="TruD, catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001656">
        <property type="entry name" value="PsdUridine_synth_TruD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020119">
        <property type="entry name" value="PsdUridine_synth_TruD_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011760">
        <property type="entry name" value="PsdUridine_synth_TruD_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042214">
        <property type="entry name" value="TruD_catalytic"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13326:SF21">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE PUS7L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13326">
        <property type="entry name" value="TRNA PSEUDOURIDINE SYNTHASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01142">
        <property type="entry name" value="TruD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50984">
        <property type="entry name" value="TRUD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01268">
        <property type="entry name" value="UPF0024"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TRUD" evidence="5">
        <location>
            <begin position="565"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="424"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1003" mass="118967" checksum="8E25A532BDA554CF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2F9</accession>
    <name>A0A1J1H2F9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC1 family, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ABCK1</name>
        <name evidence="7" type="ORF">PGAL8A_00525900</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530484.1">
        <property type="nucleotide sequence ID" value="XM_028674097.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2F9"/>
    <dbReference type="GeneID" id="39733792"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00525900"/>
    <dbReference type="OMA" id="KIMNTDP"/>
    <dbReference type="OrthoDB" id="201153at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13970">
        <property type="entry name" value="ABC1_ADCK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034646">
        <property type="entry name" value="ADCK3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051409">
        <property type="entry name" value="Atypical_kinase_ADCK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43851">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43851:SF3">
        <property type="entry name" value="COENZYME Q8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="6">
        <location>
            <begin position="529"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="376"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="381"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="392"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="881" mass="105345" checksum="05E4963D51BABC43" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2G4</accession>
    <name>A0A1J1H2G4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Clu domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00509900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530327.1">
        <property type="nucleotide sequence ID" value="XM_028673923.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733632"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00509900"/>
    <dbReference type="OMA" id="YLHFEHG"/>
    <dbReference type="OrthoDB" id="626167at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025697">
        <property type="entry name" value="CLU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51823">
        <property type="entry name" value="CLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Clu" evidence="3">
        <location>
            <begin position="433"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="144"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="232"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="815"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="163"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="291"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2057" mass="243882" checksum="7D18151E89739DE8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2Z1</accession>
    <name>A0A1J1H2Z1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcription factor 25, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">TCF25</name>
        <name evidence="2" type="ORF">PGAL8A_00027900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530644.1">
        <property type="nucleotide sequence ID" value="XM_028674274.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2Z1"/>
    <dbReference type="GeneID" id="39728802"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00027900"/>
    <dbReference type="OMA" id="NINFNCY"/>
    <dbReference type="OrthoDB" id="205993at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990112">
        <property type="term" value="C:RQC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006994">
        <property type="entry name" value="TCF25/Rqc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22684">
        <property type="entry name" value="NULP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22684:SF0">
        <property type="entry name" value="RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT TCF25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04910">
        <property type="entry name" value="Tcf25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="734" mass="87717" checksum="DC6FFA5FF349A760" modified="2017-02-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3E9</accession>
    <name>A0A1J1H3E9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Origin recognition complex subunit 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ORC2</name>
        <name evidence="8" type="ORF">PGAL8A_00045400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ORC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530820.1">
        <property type="nucleotide sequence ID" value="XM_028674471.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3E9"/>
    <dbReference type="GeneID" id="39728979"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00045400"/>
    <dbReference type="OMA" id="PHTHIKE"/>
    <dbReference type="OrthoDB" id="346673at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005664">
        <property type="term" value="C:nuclear origin of replication recognition complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007220">
        <property type="entry name" value="ORC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056772">
        <property type="entry name" value="RecA-like_ORC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056773">
        <property type="entry name" value="WHD_ORC2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14052">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14052:SF0">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04084">
        <property type="entry name" value="RecA-like_ORC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24882">
        <property type="entry name" value="WHD_ORC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Origin recognition complex subunit 2 RecA-like" evidence="6">
        <location>
            <begin position="481"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="domain" description="Origin recognition complex subunit 2 winged-helix" evidence="7">
        <location>
            <begin position="705"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="228"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="364"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="256"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="282"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF24882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG98023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="772" mass="92375" checksum="95E7DB1ACD3393F2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2012-07-11" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>I2FKD1</accession>
    <name>I2FKD1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">L-lactate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">MDH</name>
        <name evidence="12" type="ORF">PGAL8A_00146900</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Gene" volume="502" first="36" last="39">
            <title>Age of the last common ancestor of extant Plasmodium parasite lineages.</title>
            <authorList>
                <person name="Hayakawa T."/>
                <person name="Tachibana S."/>
                <person name="Hikosaka K."/>
                <person name="Arisue N."/>
                <person name="Matsui A."/>
                <person name="Horii T."/>
                <person name="Tanabe K."/>
            </authorList>
            <dbReference type="PubMed" id="22555021"/>
            <dbReference type="DOI" id="10.1016/j.gene.2012.04.037"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(S)-lactate + NAD(+) = pyruvate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23444"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16651"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.27"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the LDH/MDH superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AB571140">
        <property type="protein sequence ID" value="BAM15616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="I2FKD1"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00146900"/>
    <dbReference type="OMA" id="EIMINAQ"/>
    <dbReference type="OrthoDB" id="4069699at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004459">
        <property type="term" value="F:L-lactate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006089">
        <property type="term" value="P:lactate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01339">
        <property type="entry name" value="LDH-like_MDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000018">
        <property type="entry name" value="Malate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="entry name" value="Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011275">
        <property type="entry name" value="Malate_DH_type3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004863">
        <property type="entry name" value="PRK06223.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43128">
        <property type="entry name" value="L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+))"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43128:SF16">
        <property type="entry name" value="L-LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00086">
        <property type="entry name" value="LLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="LDH C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0520">NAD</keyword>
    <keyword evidence="2 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactate/malate dehydrogenase N-terminal" evidence="9">
        <location>
            <begin position="2"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="Lactate/malate dehydrogenase C-terminal" evidence="10">
        <location>
            <begin position="146"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="8"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="117"/>
            <end position="119"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00016495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAM15616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG93763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="313" mass="34308" checksum="64461C427D41BC69" modified="2012-07-11" version="1">MTKISLIGSGQIGALVGELCLIENLGDIVLYDIAVGTPQGKCLDLKHFSTILGVNRKILGTNNIEDIKDSDIIVITAGMQRKEGMTREDLIGINGKIMKSVAESVKLYSPNAFVICVSNPLDIMVNVFHKYSNLPHEKICGMAGILDTSRFRTLIAEKLNVSSENVNAIILGGHGDLMVPLVRYCSVSGIPLTDFVNQNFISQKDINEIVEKTRDGGAEIIKLAKASACFAPAAAIVKMIKSYLFNQNQLFTCAVYLKGIYNCDNLFVGTTATINSKGAFPVEFPLTKEEQELYDKSIQHVRENTHKAFNMIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-01-07" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A097F765</accession>
    <name>A0A097F765_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Elongation of fatty acids protein</fullName>
            <ecNumber evidence="10">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ELO3</name>
        <name evidence="13" type="ORF">PGAL8A_00432800</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2014" name="Malar. J." volume="13" first="382" last="382">
            <title>Transcriptome sequencing and analysis of Plasmodium gallinaceum reveals polymorphisms and selection on the apical membrane antigen-1.</title>
            <authorList>
                <person name="Lauron E.J."/>
                <person name="Oakgrove K.S."/>
                <person name="Tell L.A."/>
                <person name="Biskar K."/>
                <person name="Roy S.W."/>
                <person name="Sehgal R.N."/>
            </authorList>
            <dbReference type="PubMed" id="25261185"/>
            <dbReference type="DOI" id="10.1186/1475-2875-13-382"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>an acyl-CoA + malonyl-CoA + H(+) = a 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:50252"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:50253"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the ELO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="10"/>
    <dbReference type="EMBL" id="KJ722599">
        <property type="protein sequence ID" value="AIT18316.1"/>
        <property type="molecule type" value="mRNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A097F765"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00432800"/>
    <dbReference type="OrthoDB" id="10259681at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009922">
        <property type="term" value="F:fatty acid elongase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034625">
        <property type="term" value="P:fatty acid elongation, monounsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034626">
        <property type="term" value="P:fatty acid elongation, polyunsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019367">
        <property type="term" value="P:fatty acid elongation, saturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002076">
        <property type="entry name" value="ELO_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157:SF126">
        <property type="entry name" value="ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157">
        <property type="entry name" value="FATTY ACID ACYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01151">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="9 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="148"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="215"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="245"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="269"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="465"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="382"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="382"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="AIT18316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG96747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="521" mass="61651" checksum="1298FA3A2F8B75B3" modified="2015-01-07" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKX5</accession>
    <name>A0A1J1GKX5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Transmembrane emp24 domain-containing protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00074200</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the EMP24/GP25L family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525860.1">
        <property type="nucleotide sequence ID" value="XM_028675045.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKX5"/>
    <dbReference type="GeneID" id="39729267"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00074200"/>
    <dbReference type="OMA" id="YYICISC"/>
    <dbReference type="OrthoDB" id="3427at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015720">
        <property type="entry name" value="Emp24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009038">
        <property type="entry name" value="GOLD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22811">
        <property type="entry name" value="TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01105">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01190">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50866">
        <property type="entry name" value="GOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013040364" evidence="9">
        <location>
            <begin position="27"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="GOLD" evidence="10">
        <location>
            <begin position="36"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG93038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="213" mass="24423" checksum="8618EE4394AD0758" modified="2017-02-15" version="1">MKGIKTSGIVFLLFFSIFLISSNVKAAYFYVKEGVDKCFVESVASNIVITSSYDNYGLKDVKCLINIKDQNGRVLYSHETSKITKGKISYLTNKDGLYYICISCPSTNWFKSTSIKWTLSIDVGGTDIDLENLAKKSELSETLSILKSLKKKFNSMKLQQGYQKHMATNLHEYNESVHKKMFYCYITEIILLILITIYSIVHLKNYFKSQKLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL81</accession>
    <name>A0A1J1GL81_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Filament assembling protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00079400</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SF-assemblin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525914.1">
        <property type="nucleotide sequence ID" value="XM_028670399.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL81"/>
    <dbReference type="GeneID" id="39729319"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00079400"/>
    <dbReference type="OMA" id="FDINEKC"/>
    <dbReference type="OrthoDB" id="436841at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008374">
        <property type="entry name" value="SF_assemblin/giardin_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40412">
        <property type="entry name" value="SF-ASSEMBLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40412:SF1">
        <property type="entry name" value="SF-ASSEMBLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06705">
        <property type="entry name" value="SF-assemblin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01799">
        <property type="entry name" value="SFASSEMBLIN"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="266"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="353"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="514" mass="60741" checksum="B99F2FC9CAF5E13A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLR6</accession>
    <name>A0A1J1GLR6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00097300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526089.1">
        <property type="nucleotide sequence ID" value="XM_028672344.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLR6"/>
    <dbReference type="GeneID" id="39729497"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00097300"/>
    <dbReference type="OrthoDB" id="366081at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="855"/>
            <end position="882"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="966" mass="116253" checksum="D3DC34EBAC9EFC2F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLZ0</accession>
    <name>A0A1J1GLZ0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dynein light chain, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00095100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526067.1">
        <property type="nucleotide sequence ID" value="XM_028672099.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLZ0"/>
    <dbReference type="GeneID" id="39729475"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00095100"/>
    <dbReference type="OrthoDB" id="10033309at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.740.10">
        <property type="entry name" value="Protein Inhibitor Of Neuronal Nitric Oxide Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037177">
        <property type="entry name" value="DLC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001372">
        <property type="entry name" value="Dynein_light_chain_typ-1/2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01221">
        <property type="entry name" value="Dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01375">
        <property type="entry name" value="Dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54648">
        <property type="entry name" value="DLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="97" mass="11664" checksum="A24E880DBF70B0D9" modified="2017-02-15" version="1">MEEPKCDILYEHMNCEKKIKLINIAKEIYNSINNNKINSWRSATIALRDKIKDIFDFNEKGWHIIIGYKFGFFCTHEIYNALHFKLDHIEFLIFKHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMB0</accession>
    <name>A0A1J1GMB0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00108600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526203.1">
        <property type="nucleotide sequence ID" value="XM_028673610.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMB0"/>
    <dbReference type="GeneID" id="39729612"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00108600"/>
    <dbReference type="OrthoDB" id="387504at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="7"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="547" mass="65805" checksum="8FF553B627E5DF67" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMB6</accession>
    <name>A0A1J1GMB6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00118100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526297.1">
        <property type="nucleotide sequence ID" value="XM_028674655.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMB6"/>
    <dbReference type="GeneID" id="39729706"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00118100"/>
    <dbReference type="OMA" id="ECVNINV"/>
    <dbReference type="OrthoDB" id="384590at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="779"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="784"/>
            <end position="804"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="987" mass="118953" checksum="A9E5095D53CC727D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMD5</accession>
    <name>A0A1J1GMD5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Vacuolar protein 14 C-terminal Fig4-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00126800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VAC14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526383.1">
        <property type="nucleotide sequence ID" value="XM_028674787.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729793"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00126800"/>
    <dbReference type="OrthoDB" id="5574975at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070772">
        <property type="term" value="C:PAS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006661">
        <property type="term" value="P:phosphatidylinositol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026825">
        <property type="entry name" value="Vac14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021841">
        <property type="entry name" value="VAC14_Fig4p-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16023:SF0">
        <property type="entry name" value="PROTEIN VAC14 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16023">
        <property type="entry name" value="TAX1 BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12755">
        <property type="entry name" value="Vac14_Fab1_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11916">
        <property type="entry name" value="Vac14_Fig4_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Vacuolar protein 14 C-terminal Fig4-binding" evidence="7">
        <location>
            <begin position="1074"/>
            <end position="1247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="128"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="774"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1292"/>
            <end position="1324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="783"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="794"/>
            <end position="863"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF11916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1388" mass="164901" checksum="8315F897EC6B5123" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMK6</accession>
    <name>A0A1J1GMK6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Plasmodium RESA N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00000800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000018">
        <property type="protein sequence ID" value="CRG93596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526418.1">
        <property type="nucleotide sequence ID" value="XM_028674826.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMK6"/>
    <dbReference type="GeneID" id="39728530"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00000800"/>
    <dbReference type="OMA" id="ESSSYRW"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012158942" description="Plasmodium RESA N-terminal domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="203" mass="24521" checksum="3C55BAB8BB712A25" modified="2017-02-15" version="1">MTSAVILLKPFLISLSSKCLFNQKSQSVSIIKFNKEYLRILAEEEAEIKYKILNFDIPYVTYYNNFNNKTDSLIQKMLSVWENSCNDLRKNFSSYEREWEVGHFDQWYNKVSDDIKSFYEKVLAEYIPLWISRPSDKECHKFFKKKEKDLSNLCKVLEEWFTKYIKKCKDEWYPSKSKNVPTFYKSFFKCKKKDYKPLVDNPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMU8</accession>
    <name>A0A1J1GMU8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA pseudouridylate synthase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00129600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526411.1">
        <property type="nucleotide sequence ID" value="XM_028674818.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMU8"/>
    <dbReference type="GeneID" id="39729821"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00129600"/>
    <dbReference type="OrthoDB" id="440619at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="entry name" value="RNA-binding S4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050343">
        <property type="entry name" value="RsuA_PseudoU_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47683">
        <property type="entry name" value="PSEUDOURIDINE SYNTHASE FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47683:SF2">
        <property type="entry name" value="RNA-BINDING S4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55174">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RNA-binding S4" evidence="3">
        <location>
            <begin position="13"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="393" mass="45989" checksum="18513BE6AC029CE2" modified="2017-02-15" version="1">MFPAVQIKKTTFLRLSKILSLSSITSRSKAQELIKNGKVKVNNQIINKNVLTDVNSNIEINGIKINVDIRTKLWGIYKPKHVFCNTDKNYEYEEKEIANNNRMLNDNKMNYQNYEDKKYIKYLNDNNNRKISLIDSNCDKTLVIKSNSSTKNETEIRKNFDRNFLIEPNKRELLVSNNIRVSSNSKLNMNIFDFIRKKNILYEKKNKINNFIPDHLIIINSLDSHSEGLVLFTNDGDFAKNLRNVNNNILTTYLIKVQGELSQEKLKLLEKGCTIRNTRISPLSVEIIKSKFMSKWIKLTYVEKSKTDLDFLFSKYNLVIRKCKRFSFGPYKSSDLSEDFFMPLKVHSTINHLLPKYTSKLTLTEPDGNRITDSNEKYIYVKNYLQNTLIQNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMW1</accession>
    <name>A0A1J1GMW1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00137200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526489.1">
        <property type="nucleotide sequence ID" value="XM_028674905.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMW1"/>
    <dbReference type="GeneID" id="39729897"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00137200"/>
    <dbReference type="OMA" id="NDFENNC"/>
    <dbReference type="OrthoDB" id="372727at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012565841" evidence="3">
        <location>
            <begin position="23"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="69"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="215"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="73"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="373" mass="44882" checksum="4D0286ACD575819E" modified="2017-02-15" version="1">MYYLNYKLIILFILLFFEENEEFKSENEDNENEFIHNKEYINNEDNVRGTFLNINEEVESVQDKMYKFKKNEESEENEENDVYEENDVYEENDVYEVNEGNEENEGNEGNEGNEENEENEENEENEENEENEENEENEENEENELYEQNELYEQNEQNIDEIVHNNTEDEIKDNEEEQELMKENKEDLKPEENKNVIYIDNQNIYDSTHQERNEITEYLENYQVINEENKEKKKENEEKEKVKEERKNIEIIKQVKNELKKKNDELQVDENNVDVKCEKEKYENSVIQSLDQKNVNSFEGINKKFDLPSLSPTDILISRKENENMTMYHFNPQKVGYKYNNGLKPSEGYLLIYPHVSNNSMPPKIKKKKVGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMW4</accession>
    <name>A0A1J1GMW4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribonuclease P/MRP protein subunit RPP1, putative</fullName>
            <ecNumber evidence="4">3.1.26.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPP1</name>
        <name evidence="4" type="ORF">PGAL8A_00150000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic/archaeal RNase P protein component 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.5" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526614.1">
        <property type="nucleotide sequence ID" value="XM_028675043.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMW4"/>
    <dbReference type="GeneID" id="39730024"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00150000"/>
    <dbReference type="OrthoDB" id="17948at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005655">
        <property type="term" value="C:nucleolar ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002738">
        <property type="entry name" value="RNase_P_p30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13031:SF0">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13031">
        <property type="entry name" value="RIBONUCLEASE P SUBUNIT P30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01876">
        <property type="entry name" value="RNase_P_p30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="PHP domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="324" mass="37849" checksum="1BCC0CCBECB02701" modified="2017-02-15" version="1">MYVDLNIKFSSKKNTKALIYKALNIGYSIVAISINYDLNCKYDEKWKIVNCFKYNDIVHKSYNNETSNYFIDNINDVDIMNDYLLNINNNIEENFILINRTNTLCIKDVCDDFIFNKKNEITQEELKNVYNLLPSENFFLSNNNSTYVLKRLNIKYQDALKMENYNKYIKENNFDLIGIEVTSAEEINLAASKFDCDIIYFDLKKCFISLRKSDIQNALDRGIFFEISSLNTITEDYQYVILALNINNLFSVIPLNKLIFSSGSLKENEIIEPLHFLRLFFNFNTLSYKDVIQCITNVPISCIQRASVRKSLNTAVFFKSAETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMZ5</accession>
    <name>A0A1J1GMZ5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00150200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526615.1">
        <property type="nucleotide sequence ID" value="XM_028675044.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730026"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00150200"/>
    <dbReference type="OMA" id="ALCYACF"/>
    <dbReference type="OrthoDB" id="385235at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035770">
        <property type="term" value="C:ribonucleoprotein granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000963">
        <property type="term" value="P:mitochondrial RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044528">
        <property type="term" value="P:regulation of mitochondrial mRNA stability"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050870">
        <property type="entry name" value="FAST_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013584">
        <property type="entry name" value="RAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058917">
        <property type="entry name" value="RESC6_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21228">
        <property type="entry name" value="FAST LEU-RICH DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21228:SF40">
        <property type="entry name" value="LD45607P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26188">
        <property type="entry name" value="RESC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00952">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RAP" evidence="1">
        <location>
            <begin position="1439"/>
            <end position="1496"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1528" mass="182471" checksum="F53735B7700553DC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN22</accession>
    <name>A0A1J1GN22_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Rhomboid-like protease</fullName>
            <ecNumber evidence="10">3.4.21.105</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ROM10</name>
        <name evidence="12" type="ORF">PGAL8A_00147000</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Serine protease involved in intramembrane proteolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that are contributed by different transmembrane domains.</text>
            <dbReference type="EC" id="3.4.21.105"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Membrane</location>
            <topology evidence="2 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the peptidase S54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.105" evidence="10"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526586.1">
        <property type="nucleotide sequence ID" value="XM_028675013.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN22"/>
    <dbReference type="GeneID" id="39729994"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00147000"/>
    <dbReference type="OMA" id="TNNHQYY"/>
    <dbReference type="OrthoDB" id="418595at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002610">
        <property type="entry name" value="Peptidase_S54_rhomboid-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22936:SF69">
        <property type="entry name" value="RHOMBOID-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22936">
        <property type="entry name" value="RHOMBOID-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10 12" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="43"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="221"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="250"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S54 rhomboid" evidence="11">
        <location>
            <begin position="102"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG93764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="274" mass="31747" checksum="57113D4D6EA90DD0" modified="2017-02-15" version="1">MNFHSNSSNHLNYEHPYDSNLLIQKYTQSFNNTFKRDIKFIQILFPTFDIFSITFFFSLFLILIFLCLDVYFFNSQKPLYINEDILKNIGINKFYISNGYHYYKIISATFIHSNIWNLIINTYYLMNIGIIIEKNYGKLKYIILMFLCAICGNLLTCATAKCNDIQMGISPILSGFIGVFLQEIIMHYNDVKDKLSVIGNFIFAFLSLYLMISIFPYNGNIFGNTGGLFVGISYPFIFKSDSFNNTDKKLKITFIILIILLISATLSSIIIFKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN43</accession>
    <name>A0A1J1GN43_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Secreted ookinete protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PSOP6</name>
        <name evidence="2" type="ORF">PGAL8A_00158700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526700.1">
        <property type="nucleotide sequence ID" value="XM_028675139.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN43"/>
    <dbReference type="GeneID" id="39730112"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00158700"/>
    <dbReference type="OMA" id="HAPEEDT"/>
    <dbReference type="OrthoDB" id="329189at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012113929" evidence="1">
        <location>
            <begin position="23"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="133" mass="15681" checksum="AE50F90EE7030702" modified="2017-02-15" version="1">MNYFLVSFCFLLLCIMQNFVLNEKIIPIGPANRSKLKKMIEGDEDFKINIHAPVEDTQEVLEALDSLMRVEEIQRKVEEEEFRNDMQRLLKVHKKRIQDIVSSAFEPLHSFLPNPLQYLVIKDVQSYLKSIKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNI1</accession>
    <name>A0A1J1GNI1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sec14-like cytosolic factor or phosphatidylinositol/phosphatidylcholine transfer protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00158400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526697.1">
        <property type="nucleotide sequence ID" value="XM_028675136.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNI1"/>
    <dbReference type="GeneID" id="39730109"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00158400"/>
    <dbReference type="OMA" id="PADCEWF"/>
    <dbReference type="OrthoDB" id="1434354at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051064">
        <property type="entry name" value="SEC14/CRAL-TRIO_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324">
        <property type="entry name" value="SEC14 RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23324:SF83">
        <property type="entry name" value="SEC14-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="116"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="295"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="326" mass="37991" checksum="0672A7B58E42B75D" modified="2017-02-15" version="1">MSITPGNISYNLDVLLKKYEEQIKTVKRLMKIKNIKDNVEDIILIRYILSYGDKLEDAVNSIEKAILWRKKNVYPLLKNKKIHSGNNDLLFPDRLKPYYSFIKKTLAACEHKSTVDNQPVVIARLKLCNFTLLLDNVPENILVDYIVYSNEHEFIVCNEQTKKSNVLCRTYRFIDLKGFMLKKFDRRFLRVFANTSKLSEFLHPQLVGKTYLINAPSYIRITIETLKTFGISKRTLNKLEIPKIIAGREPADCDWFTLLVHKDDIPTYFGGNCRCENGCIPGFENDLDDPLNLNIEEIKAEIKNNFKKLKMKKNEDTQNLENSQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNP0</accession>
    <name>A0A1J1GNP0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dynein attachment factor N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00380100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526918.1">
        <property type="nucleotide sequence ID" value="XM_028670136.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNP0"/>
    <dbReference type="GeneID" id="39732331"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00380100"/>
    <dbReference type="OMA" id="FVRCIIK"/>
    <dbReference type="OrthoDB" id="372166at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031733">
        <property type="entry name" value="Dynein_attach_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15867">
        <property type="entry name" value="Dynein_attach_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynein attachment factor N-terminal" evidence="1">
        <location>
            <begin position="11"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF15867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="260" mass="31472" checksum="07412964FE0FDA65" modified="2017-02-15" version="1">MRLNENITHSLNLKKMRNDFIKSIMRDDEYKKKDDKKKEIVKSCKSYKDFCNIVDSVNMKPIRKYEEKVSYEDYINLNICPFNSKSEYLQEKKRRNNLNFMITQFKINNKKEKFDSLIDKSHTKSSEIKQFLNILKINKDNYYGFIKSNCNCDDIKYFIYIIKNNLNVLLEDNNSNEENNILDDENRKEDYNFNLLNTINFLFYLSKHWSNENFSMFFIEDELSDISLNINTIIDEIKKKSNKHDKLIEKFNYIKNIFSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNR4</accession>
    <name>A0A1J1GNR4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L13, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00380200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526919.1">
        <property type="nucleotide sequence ID" value="XM_028670137.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNR4"/>
    <dbReference type="GeneID" id="39732332"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00380200"/>
    <dbReference type="OMA" id="HMMGRLA"/>
    <dbReference type="OrthoDB" id="1882297at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1180.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_uL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_uL13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023563">
        <property type="entry name" value="Ribosomal_uL13_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005755">
        <property type="entry name" value="Ribosomal_uL13_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_uL13_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01077">
        <property type="entry name" value="L13_A_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="RIBOSOMAL PROTEIN L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00783">
        <property type="entry name" value="RIBOSOMAL_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="202" mass="23663" checksum="6BB95357553013F0" modified="2017-02-15" version="1">MFKKVYVIDCKGHLLGRLASIIAKELLKGQRVVAVRCEEINISGSLYRNKLKYSKFLRLRTNTNPRKGPFHLREPSKILWRCVRGMLPHKTFKGKIALKKLKVFVGVPYPYDKMKKYVLPSALRAFRLKKNRRYCRLGTLSSRVGWNYDDLVKKNEALRKKVSKTFYKKKVNSLNEKKELKTKALSLINPEQRQVLENFGYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNS5</accession>
    <name>A0A1J1GNS5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">histone deacetylase</fullName>
            <ecNumber evidence="4">3.5.1.98</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">HDA2</name>
        <name evidence="15" type="ORF">PGAL8A_00384100</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the histone deacetylase family. HD type 2 subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the inositol phosphokinase (IPK) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.98" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526958.1">
        <property type="nucleotide sequence ID" value="XM_028670180.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732371"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00384100"/>
    <dbReference type="OMA" id="AWLYLCC"/>
    <dbReference type="OrthoDB" id="424012at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141221">
        <property type="term" value="F:histone deacetylase activity, hydrolytic mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040029">
        <property type="term" value="P:epigenetic regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032958">
        <property type="term" value="P:inositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09992">
        <property type="entry name" value="HDAC_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.160">
        <property type="entry name" value="Inositol polyphosphate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005522">
        <property type="entry name" value="IPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038286">
        <property type="entry name" value="IPK_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF5">
        <property type="entry name" value="HISTONE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03770">
        <property type="entry name" value="IPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="8 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0678">Repressor</keyword>
    <keyword evidence="11" id="KW-0804">Transcription</keyword>
    <keyword evidence="10" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="14">
        <location>
            <begin position="314"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="Histone deacetylase" evidence="14">
        <location>
            <begin position="504"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="domain" description="Histone deacetylase" evidence="14">
        <location>
            <begin position="688"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="654"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="659"/>
            <end position="674"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG94137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1738" mass="205618" checksum="1CBE92BB1F1F67FB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP30</accession>
    <name>A0A1J1GP30_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase</fullName>
            <ecNumber evidence="5">2.7.8.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">GlcNAc-1-P transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">N-acetylglucosamine-1-phosphate transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">PGAL8A_00395100</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis, transfering GlcNAc-1-P from cytosolic UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol embedded in the cytoplasmic leaflet of the endoplasmic reticulum membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>a di-trans,poly-cis-dolichyl phosphate + UDP-N-acetyl-alpha-D-glucosamine = an N-acetyl-alpha-D-glucosaminyl-diphospho-di-trans,poly-cis-dolichol + UMP</text>
            <dbReference type="Rhea" id="RHEA:13289"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19507"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58427"/>
            <dbReference type="EC" id="2.7.8.15"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="18">
            <dbReference type="Rhea" id="RHEA:13290"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyltransferase 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.15" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527068.1">
        <property type="nucleotide sequence ID" value="XM_028670302.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP30"/>
    <dbReference type="GeneID" id="39732481"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00395100"/>
    <dbReference type="OMA" id="LPHFNAR"/>
    <dbReference type="OrthoDB" id="10262326at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003975">
        <property type="term" value="F:UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06855">
        <property type="entry name" value="GT_GPT_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033895">
        <property type="entry name" value="GPT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10571">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10571:SF0">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="24"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="49"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="218"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="257"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="284"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="310"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="349"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="373"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00029567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00033238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00045078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="CRG94247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="398" mass="46790" checksum="A03B32263553E414" modified="2017-02-15" version="1">MKICIESNENKKLMAYKENISEKNLFYVLFIYLLIVFFLLKKTPFKNIILFYITPCLILFKVTFMCLPKFIHFLNEKGFYGFDLNKISKDKVAEPIGLFPAILYFIFVLFYQMIYYNDNKILLEYNAGLLSIIFMTFLGFIDDIFELKWRYKVALPFFACLPLLLSYSGETNIRIPNFLYFIFKERIINIGFFYYLYIILLAVFCTNAINIYSGINGLEIGQSLIISFFISIHNLIEIILNIDKSSVESKLILKQHFLSIIFTLPFISINLVTFSFNFYPSKGFVGNTLTYFCGIFLAVVSIFGHYSKTLILFLIPQFLNFFISLPQLFNFIPCPRHRLPNLNKKTNKLIYSHNYTLINLILYLFGPLSEFHLVNVLLFFQIITCSFGLFLRYFIDTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP45</accession>
    <name>A0A1J1GP45_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ubiquinol-cytochrome c reductase complex subunit, putative</fullName>
            <ecNumber evidence="9">1.10.2.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00388500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UQCRB/QCR7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.10.2.2" evidence="9"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527002.1">
        <property type="nucleotide sequence ID" value="XM_028670229.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP45"/>
    <dbReference type="GeneID" id="39732415"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00388500"/>
    <dbReference type="OrthoDB" id="425749at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045275">
        <property type="term" value="C:respiratory chain complex III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1090.10">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003197">
        <property type="entry name" value="QCR7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036544">
        <property type="entry name" value="QCR7_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12022:SF0">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12022">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 14 KD PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02271">
        <property type="entry name" value="UCR_14kD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81524">
        <property type="entry name" value="14 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="192" mass="22983" checksum="2A8EB151D7D8D337" modified="2017-02-15" version="1">MSLHKEICKYIIKCGNKSVPKIQYEATKKKPCKITDFYRKYIFPYYFKYIRAPFERWQYCATTKFLREHGLMYDDMYSDKDPVIERALSLLPKDIQIKRYRRMLRGTHLNYLRLLLHPSEQNYDPYIPYLAPYIEEAKFQLQEEEELLGYHPYDRRLYSGGTTGFGDLEPGLHFLVSIPNVYGAAIPHMKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPD9</accession>
    <name>A0A1J1GPD9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00398900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527106.1">
        <property type="nucleotide sequence ID" value="XM_028670345.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPD9"/>
    <dbReference type="GeneID" id="39732519"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00398900"/>
    <dbReference type="OMA" id="HIIWQKA"/>
    <dbReference type="OrthoDB" id="1938138at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000811">
        <property type="term" value="C:GINS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11712">
        <property type="entry name" value="GINS_A_psf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036224">
        <property type="entry name" value="GINS_bundle-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007257">
        <property type="entry name" value="GINS_Psf2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12772">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12772:SF0">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158573">
        <property type="entry name" value="GINS helical bundle-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="469" mass="55667" checksum="C5D0BBDCE8AD4E85" modified="2017-02-15" version="1">MSDVFSIFRRKRNKKTKLCKTSNKKSKRNILMNDKCRRRAYVNNNVKQDNTQVEINNHESNIVLVDFPKLPIKNIELCEGVYNIFYIRDQYLIGNKNVTINNEHLILLETILDKLDSAINELNSEENYSTKKILSSVYEKIATLYNSFKNIKNKLPQLSNAYDCFKSNIIFVRGKQFKKNYVYDNLINIYTYLQDSELQQDNIETINQTLHINDQAISSPSFINKNLVTSNEYIEYLPMKFNPHFLELNKISIYYLFEESINHIIWQKALDELIVVKALADIPYFDLTEVEGFDFQKMKSGQRQWYPLYIAKELSEEGLATVEFPFWFYIDNLKNIYKKEFEDMNELTDLPSPFFFEISSMFLENNAFKNSTPIETIGQKTPYKYILKVAGLIQDIRQKRIHKIMNKFKNCDIFSEILIINNIQIYETYCVNYLASVFFQRQNSSYSMDENFDVRNYLFDPFIFSSYNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPL3</accession>
    <name>A0A1J1GPL3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00406900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527186.1">
        <property type="nucleotide sequence ID" value="XM_028670434.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPL3"/>
    <dbReference type="GeneID" id="39732599"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00406900"/>
    <dbReference type="OMA" id="CLIHKSI"/>
    <dbReference type="OrthoDB" id="371137at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1009"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1037"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="127"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1133" mass="136999" checksum="502D490C8F9FB719" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPP0</accession>
    <name>A0A1J1GPP0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-f protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00187000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000025">
        <property type="protein sequence ID" value="CRG94475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527294.1">
        <property type="nucleotide sequence ID" value="XM_028670553.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPP0"/>
    <dbReference type="GeneID" id="39730397"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00187000"/>
    <dbReference type="OrthoDB" id="1490254at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="603" mass="72664" checksum="527F7DF0D12F4676" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPX5</accession>
    <name>A0A1J1GPX5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein kinase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00077600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525896.1">
        <property type="nucleotide sequence ID" value="XM_028670200.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPX5"/>
    <dbReference type="GeneID" id="39729301"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00077600"/>
    <dbReference type="OMA" id="NRNKGIN"/>
    <dbReference type="OrthoDB" id="339325at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF288">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="768"/>
            <end position="1025"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1036" mass="122534" checksum="B0F0B3C47CF1F339" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQA0</accession>
    <name>A0A1J1GQA0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ubiquitin-protein ligase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00207600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527494.1">
        <property type="nucleotide sequence ID" value="XM_028670775.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQA0"/>
    <dbReference type="GeneID" id="39730603"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00207600"/>
    <dbReference type="OMA" id="GFMHYYG"/>
    <dbReference type="OrthoDB" id="27934at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052945">
        <property type="entry name" value="Mitotic_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628">
        <property type="entry name" value="ACTIVATOR OF C KINASE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43628:SF1">
        <property type="entry name" value="CHITIN SYNTHASE REGULATORY FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012068589" evidence="1">
        <location>
            <begin position="28"/>
            <end position="785"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="785" mass="92469" checksum="A575244C307AE846" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQK8</accession>
    <name>A0A1J1GQK8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Small ribosomal subunit assembling AARP2 protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">AARP2</name>
        <name evidence="13" type="ORF">PGAL8A_00102800</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the TRAFAC class translation factor GTPase superfamily. Bms1-like GTPase family. BMS1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526144.1">
        <property type="nucleotide sequence ID" value="XM_028672954.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQK8"/>
    <dbReference type="GeneID" id="39729553"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00102800"/>
    <dbReference type="OMA" id="KLHVPMV"/>
    <dbReference type="OrthoDB" id="10260897at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034511">
        <property type="term" value="F:U3 snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000479">
        <property type="term" value="P:endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000105">
        <property type="entry name" value="BMS1 ribosome biogenesis factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012948">
        <property type="entry name" value="AARP2CN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039761">
        <property type="entry name" value="Bms1/Tsr1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007034">
        <property type="entry name" value="BMS1_TSR1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030387">
        <property type="entry name" value="G_Bms1/Tsr1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12858">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12858:SF2">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BMS1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08142">
        <property type="entry name" value="AARP2CN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04950">
        <property type="entry name" value="RIBIOP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00785">
        <property type="entry name" value="AARP2CN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01362">
        <property type="entry name" value="DUF663"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51714">
        <property type="entry name" value="G_BMS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Bms1-type G" evidence="12">
        <location>
            <begin position="71"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="389"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="788"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="390"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="402"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="415"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="789"/>
            <end position="842"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00061391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG93322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1263" mass="149358" checksum="3591C267342089EA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQL2</accession>
    <name>A0A1J1GQL2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">DH60</name>
        <name evidence="18" type="ORF">PGAL8A_00128200</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526397.1">
        <property type="nucleotide sequence ID" value="XM_028674803.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQL2"/>
    <dbReference type="GeneID" id="39729807"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00128200"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00268">
        <property type="entry name" value="DEADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000008">
        <property type="entry name" value="ATP-dependent RNA helicase RhlB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044742">
        <property type="entry name" value="DEAD/DEAH_RhlB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 13 18" id="KW-0347">Helicase</keyword>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="17">
        <location>
            <begin position="271"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="15">
        <location>
            <begin position="301"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="16">
        <location>
            <begin position="544"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="170"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="12">
        <location>
            <begin position="271"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="CRG93575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="700" mass="81999" checksum="A073267FDFF78C96" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQM4</accession>
    <name>A0A1J1GQM4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">YL1 nuclear protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00223400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS72/YL1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527652.1">
        <property type="nucleotide sequence ID" value="XM_028670950.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQM4"/>
    <dbReference type="GeneID" id="39730761"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00223400"/>
    <dbReference type="OMA" id="YAYMENL"/>
    <dbReference type="OrthoDB" id="49520at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013272">
        <property type="entry name" value="Vps72/YL1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046757">
        <property type="entry name" value="YL1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13275:SF4">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 72 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13275">
        <property type="entry name" value="YL-1 PROTEIN TRANSCRIPTION FACTOR-LIKE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05764">
        <property type="entry name" value="YL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08265">
        <property type="entry name" value="YL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00993">
        <property type="entry name" value="YL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vps72/YL1 C-terminal" evidence="3">
        <location>
            <begin position="596"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="452"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="24"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="36"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="125"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="141"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="185"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="464"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="667" mass="80863" checksum="EEE63D8B3A38F63E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQN5</accession>
    <name>A0A1J1GQN5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fam-f protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00130400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526421.1">
        <property type="nucleotide sequence ID" value="XM_028674829.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQN5"/>
    <dbReference type="GeneID" id="39729829"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00130400"/>
    <dbReference type="OrthoDB" id="384364at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="574" mass="69170" checksum="445DBC3298549AB3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQP1</accession>
    <name>A0A1J1GQP1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cleavage and polyadenylation specificity factor, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00197700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527395.1">
        <property type="nucleotide sequence ID" value="XM_028670665.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQP1"/>
    <dbReference type="GeneID" id="39730504"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00197700"/>
    <dbReference type="OMA" id="DNREVIC"/>
    <dbReference type="OrthoDB" id="10249535at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004534">
        <property type="term" value="F:5'-3' RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006398">
        <property type="term" value="P:mRNA 3'-end processing by stem-loop binding and cleavage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16292">
        <property type="entry name" value="CPSF3-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10890:FF:000001">
        <property type="entry name" value="Cleavage and polyadenylation specificity factor subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022712">
        <property type="entry name" value="Beta_Casp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021718">
        <property type="entry name" value="CPSF73-100_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050698">
        <property type="entry name" value="MBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011108">
        <property type="entry name" value="RMMBL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11203">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11203:SF11">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10996">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11718">
        <property type="entry name" value="CPSF73-100_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16661">
        <property type="entry name" value="Lactamase_B_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07521">
        <property type="entry name" value="RMMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01027">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01098">
        <property type="entry name" value="CPSF73-100_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="7">
        <location>
            <begin position="16"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-Casp" evidence="8">
        <location>
            <begin position="290"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term" evidence="9">
        <location>
            <begin position="637"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="541"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="595"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="607"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG94580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="924" mass="107216" checksum="D7ADEC53B9864AA9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQV8</accession>
    <name>A0A1J1GQV8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00229300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527710.1">
        <property type="nucleotide sequence ID" value="XM_028671015.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQV8"/>
    <dbReference type="GeneID" id="39730820"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00229300"/>
    <dbReference type="OMA" id="ECLHKFV"/>
    <dbReference type="OrthoDB" id="391889at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="158" mass="18437" checksum="4EE393D30FD0E3B6" modified="2017-02-15" version="1">MNYLECLHKFVNAHSENFLQSLYAVVESSQIECLECPIEKTSTDNFLIKIYINNIIHNIRTLLLTCVNGSVGNLLHNTDIVKRERNIYLVDNDTSDIKTEGKKDIKNEKDNSNNNINIEDDFLNKCKKVHNIRKSLQNTHIKKNYFVNSQNNILDYYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQY5</accession>
    <name>A0A1J1GQY5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00227200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527690.1">
        <property type="nucleotide sequence ID" value="XM_028670993.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQY5"/>
    <dbReference type="GeneID" id="39730799"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00227200"/>
    <dbReference type="OMA" id="MISRECL"/>
    <dbReference type="OrthoDB" id="368496at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="92" mass="10823" checksum="0587ADD45134A92F" modified="2017-02-15" version="1">MTVNTFISRKDYNDYKLCIQSNKENNNSNEKCSNQLNKAINSASHIISRECLPYTEDLYKCFKHSFRLSFCDKEITEKLQNCHSDIYKLITS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQZ2</accession>
    <name>A0A1J1GQZ2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Aminophospholipid transporter, putative</fullName>
            <ecNumber evidence="12">3.6.3.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00228000</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.1" evidence="12"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527698.1">
        <property type="nucleotide sequence ID" value="XM_028671002.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730807"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00228000"/>
    <dbReference type="OMA" id="HTHFNTH"/>
    <dbReference type="OrthoDB" id="377733at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140326">
        <property type="term" value="F:ATPase-coupled intramembrane lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF180">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE DNF1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="271"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="306"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="696"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="724"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1529"/>
            <end position="1546"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1552"/>
            <end position="1575"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1604"/>
            <end position="1628"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1659"/>
            <end position="1685"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1691"/>
            <end position="1712"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase C-terminal" evidence="11">
        <location>
            <begin position="1495"/>
            <end position="1716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="540"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="540"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG94883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1769" mass="211664" checksum="1D1DA2D558B2E9F9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR18</accession>
    <name>A0A1J1GR18_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Serine/threonine protein kinase KIN, putative</fullName>
            <ecNumber evidence="7">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">KIN</name>
        <name evidence="7" type="ORF">PGAL8A_00213500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527553.1">
        <property type="nucleotide sequence ID" value="XM_028670840.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR18"/>
    <dbReference type="GeneID" id="39730662"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00213500"/>
    <dbReference type="OMA" id="VHENIKN"/>
    <dbReference type="OrthoDB" id="193931at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14003">
        <property type="entry name" value="STKc_AMPK-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000759">
        <property type="entry name" value="CAMK/CAMKL/AMPK protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF30">
        <property type="entry name" value="MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="498"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="404"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="4"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="412"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="527"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG94738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1115" mass="131649" checksum="3330D4B97097F08A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR24</accession>
    <name>A0A1J1GR24_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00231300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527730.1">
        <property type="nucleotide sequence ID" value="XM_028671037.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR24"/>
    <dbReference type="GeneID" id="39730840"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00231300"/>
    <dbReference type="OMA" id="PLHICAP"/>
    <dbReference type="OrthoDB" id="387192at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="258" mass="30599" checksum="C90F18D364BB45AB" modified="2017-02-15" version="1">MYATNSKTNFYSYGNNNYDPYKSYPGNDKVMGNSDNYESQYYSDGGLNLMNSHINKNDIYYKAQQNYPYDTSIYNDMQYTPLSSLHAATFNQNKNRLQNFNHNSKIFEKDTPVDNYRNSDFKIRIKNNRNKINNCNDQMDEVNDINYNSTYEDEESYDTPKNERNTVINITYDDKSSENDCIEDNEQNIYNFKKIKKPKKKFMGKYFFSEIKNNFLSPLHICAPHPTLTVPNFNCFHYKIVEKTKGKKNEKPEIVVRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR45</accession>
    <name>A0A1J1GR45_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">NifU protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00213700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; iron-sulfur cluster biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the NifU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527555.1">
        <property type="nucleotide sequence ID" value="XM_028670842.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR45"/>
    <dbReference type="GeneID" id="39730664"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00213700"/>
    <dbReference type="OMA" id="SMVTEMV"/>
    <dbReference type="OrthoDB" id="1925777at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06664">
        <property type="entry name" value="IscU_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1010.10:FF:000005">
        <property type="entry name" value="Iron-sulfur cluster assembly protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011339">
        <property type="entry name" value="ISCU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002871">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01999">
        <property type="entry name" value="iscU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10093">
        <property type="entry name" value="IRON-SULFUR CLUSTER ASSEMBLY ENZYME NIFU HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01592">
        <property type="entry name" value="NifU_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82649">
        <property type="entry name" value="SufE/NifU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NIF system FeS cluster assembly NifU N-terminal" evidence="7">
        <location>
            <begin position="34"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="157" mass="17749" checksum="BC10EFA9E37D3AFF" modified="2017-02-15" version="1">MVGKIIEICKQKEILYKFFLRGKYMNNYMYTRNYSDNVKDHFNKPRNVGSFDKNEKNIGTSIVGKASCGDVIKLQLKIEDNVIKDARFMAFGCGSAIASSSYATELIKGKTIDEALKIKNDDIASHLNLPPVKIHCSLLAEDAIKHAIKNYREKVIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRB1</accession>
    <name>A0A1J1GRB1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyclin homologue, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">CYC1</name>
        <name evidence="2" type="ORF">PGAL8A_00223100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527649.1">
        <property type="nucleotide sequence ID" value="XM_028670947.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRB1"/>
    <dbReference type="GeneID" id="39730758"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00223100"/>
    <dbReference type="OMA" id="PQIVECA"/>
    <dbReference type="OrthoDB" id="340962at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20524">
        <property type="entry name" value="CYCLIN_CCNH_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="328" mass="39698" checksum="121DE25DBC455A5F" modified="2017-02-15" version="1">MNYPEDTSHIKKWFFKNEKEINDICLKKYNDFKEKFKNYKISIPKYNDIEKTKLYFCYQLTHFCEIKMLKAQIVECAILLYNRFYLKEIILVYDPRILIFTCIILAIKLEGYGRMYKMNEFFSDIDINLDKVLEHENIVCSSLDFELNFLYTKECIYYLKNKFLNYIKKYINKDNELNNSFENICDKIYINTSNDCLKVIENFFITFTYTPSQIALYCFINNIKIYFNIVNADKFILEFITNNNQILFQKLKNKIDELHIKYKNHLDLRNTFDDENTTKQIGETLDMCIDIYELLRKKNSKKSRKKKLNDEDNTQNESNKKVDIKNEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRL7</accession>
    <name>A0A1J1GRL7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA-processing protein 42</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">RRP42</name>
        <name evidence="9" type="ORF">PGAL8A_00251100</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase PH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527922.1">
        <property type="nucleotide sequence ID" value="XM_028671251.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRL7"/>
    <dbReference type="GeneID" id="39731039"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00251100"/>
    <dbReference type="OMA" id="WTISIDI"/>
    <dbReference type="OrthoDB" id="272245at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035925">
        <property type="term" value="F:mRNA 3'-UTR AU-rich region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034473">
        <property type="term" value="P:U1 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034476">
        <property type="term" value="P:U5 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050590">
        <property type="entry name" value="Exosome_comp_Rrp42_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097:SF8">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097">
        <property type="entry name" value="EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0271">Exosome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="7">
        <location>
            <begin position="25"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="8">
        <location>
            <begin position="193"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG95109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="281" mass="31535" checksum="D6608C9D53D80BA2" modified="2017-02-15" version="1">MSCLKYIEDSINSNIRVDGRTLSTYRSIEINKNILVSADGSSSVMNEENNVICGIKLSLLTPNPDAYDEGFVNLQIDCPASIATNRIKKEHLQTMTSIIYDLCIKNNINKKKLCILPSKFVWNVDINVMVLNAGGGLLDIISIAIYVALRNTSLPVVHPKKKIEESDVFGDTQNKDYQLEIIDNQETKFPYENIPICISIGEINNKYIYDMSKIEEELVENIFVVAITSNGKCVAFHKLYGISMEISSILNIAENSSKISHSLFEKINEAIDKIKIKTSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRP8</accession>
    <name>A0A1J1GRP8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00254600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527954.1">
        <property type="nucleotide sequence ID" value="XM_028671286.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRP8"/>
    <dbReference type="GeneID" id="39731074"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00254600"/>
    <dbReference type="OMA" id="NHFAKPK"/>
    <dbReference type="OrthoDB" id="333370at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="303" mass="36524" checksum="D981805660297FE7" modified="2017-02-15" version="1">MYNTLKKKVLLVTFILIYINLKIVFNKKANYIFFKKPNYINEEAYTKYFYIPKYKAYHKKKKKIKICNSYNESNKIRPERKMECYELNIRNDKKFPKYAKKPACPLSNLFYFSPFKNIVDSFEPIDYNVKQRLKEEGFQFENEKKESNIFPSLDEIIKNGDPSTNMHFYRRKKLKSLLYGDPLKFVKAKKVIEKYNRRAPPEKQINYDMFRCDIYYVHSDGTIMNIEENRPPYDKKLEESQRYKEPRFLITTAPGHAKKNNLKIGDKFPIINEKEKRKLFDNHFARPKKVRDPLILPDGRKIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRQ9</accession>
    <name>A0A1J1GRQ9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">RNA lariat debranching enzyme, putative</fullName>
            <ecNumber evidence="12">3.1.4.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">DBR1</name>
        <name evidence="12" type="ORF">PGAL8A_00251600</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.-" evidence="12"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527927.1">
        <property type="nucleotide sequence ID" value="XM_028671257.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRQ9"/>
    <dbReference type="GeneID" id="39731044"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00251600"/>
    <dbReference type="OMA" id="DFECVRY"/>
    <dbReference type="OrthoDB" id="407609at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008419">
        <property type="term" value="F:RNA lariat debranching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00844">
        <property type="entry name" value="MPP_Dbr1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007708">
        <property type="entry name" value="DBR1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041816">
        <property type="entry name" value="Dbr1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12849:SF0">
        <property type="entry name" value="LARIAT DEBRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12849">
        <property type="entry name" value="RNA LARIAT DEBRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05011">
        <property type="entry name" value="DBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01124">
        <property type="entry name" value="DBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Lariat debranching enzyme C-terminal" evidence="11">
        <location>
            <begin position="477"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="400"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="400"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG95114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="632" mass="75558" checksum="991545899F3BE2F6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRS1</accession>
    <name>A0A1J1GRS1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SUEL-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00239300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527809.1">
        <property type="nucleotide sequence ID" value="XM_028671126.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRS1"/>
    <dbReference type="GeneID" id="39730921"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00239300"/>
    <dbReference type="OMA" id="CESSSYK"/>
    <dbReference type="OrthoDB" id="361871at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22823">
        <property type="entry name" value="Gal_Rha_Lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043159">
        <property type="entry name" value="Lectin_gal-bd_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012701211" description="SUEL-type lectin domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="340" mass="39169" checksum="98F02167AF21C300" modified="2017-02-15" version="1">MYYLTFLNFFVLIITMCNNSIKCLKKKEILNGDLKILIGNLNETITLNCDNYKSIHILDASYGNPSIDKFLIKKDSLDAPHTLPVVQMICEGRTNCDININNDTFKILSLIKDFHKFIVKYSCVSTKLKTFPSYKIKSKRGDNYTWNIEFEADEISNKGIYLHVNDVNATCDSPLLKKNYLDVNEAEQECNSLNSCVFIIFNNDGYILCESSFYKNTVIQKNAKIYIKMSYIHGNLPKNFEVFPNLQGVCETSEIIYEKDEAMNLDDIYKKCKEIECDYFTMSTANGVKGASKNFRNHAWFCKGFPKYVSHEGFIFGKNNKNSSDPKQRIIFKGYEGPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRV5</accession>
    <name>A0A1J1GRV5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Protein kinase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00263700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528044.1">
        <property type="nucleotide sequence ID" value="XM_028671386.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRV5"/>
    <dbReference type="GeneID" id="39731166"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00263700"/>
    <dbReference type="OMA" id="EWFKENI"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050205">
        <property type="entry name" value="CDPK_Ser/Thr_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24349">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="422" mass="50453" checksum="AAA1897E72FD5B8A" modified="2017-02-15" version="1">MRIKNVVNNSNNIFNFFCTESETNILKDFVHIITLRENKKKKICYSYSIVDGYKYRIVIKKKKDYLNNLKLLILPLDHPNIIKLIHYCELASSFICVFEFFTDTSLYSSVVFSARYDERKIKNIIYQIILIVNYLHSNNLALKKLSPYSFLVKSVNKEVMIKLEDIYKITTISTKTNSKIKSKNVYSIGVIMYFLVCGEFPFSYLENNQKKIFFDKKLWKNISYKGRNFIKKILLNDLSSMITVKEALDHEWFKEDIKQNIYINFDILKNIYDFWKKNTFKRYILNNIAKFLIKEDIYNYNYIFSYFDMTKEGSIKYEQYFIIMKKLDLADANIQLSFNGLDISKAGLIQFSNIIASLLNSFIKIDKKIVLKFFKKVDHNNEGVLTKRKLYRFFNIKTKNEINLNDKKKFTFEEFYDYICKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS57</accession>
    <name>A0A1J1GS57_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">DNA repair protein RAD5, putative</fullName>
            <ecNumber evidence="12">3.6.4.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">RAD5</name>
        <name evidence="12" type="ORF">PGAL8A_00254500</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="12"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527953.1">
        <property type="nucleotide sequence ID" value="XM_028671285.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731073"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00254500"/>
    <dbReference type="OMA" id="LIYQWKQ"/>
    <dbReference type="OrthoDB" id="448448at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18008">
        <property type="entry name" value="DEXDc_SHPRH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF22">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="619"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="1093"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="1170"/>
            <end position="1358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG95140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1373" mass="161239" checksum="6529100E345152A6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSI5</accession>
    <name>A0A1J1GSI5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Trophozoite stage antigen, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00397600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527093.1">
        <property type="nucleotide sequence ID" value="XM_028670330.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSI5"/>
    <dbReference type="GeneID" id="39732506"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00397600"/>
    <dbReference type="OMA" id="KECDEQF"/>
    <dbReference type="OrthoDB" id="381599at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="116" mass="13571" checksum="65101D91FF719419" modified="2017-02-15" version="1">MVLTEGYLTRLYKSLYINEKGINVRKGSRSKKLSLKNETSSESSYDLKSDSVDNSMSEYQFEVFTSLNDKIRTPKKKKINKCVNTSSLKHEHNNFYATITIKCKECDEQFTRDFEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSJ7</accession>
    <name>A0A1J1GSJ7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PIR-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00266000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000035">
        <property type="protein sequence ID" value="CRG95457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528268.1">
        <property type="nucleotide sequence ID" value="XM_028671635.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSJ7"/>
    <dbReference type="GeneID" id="39731189"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00266000"/>
    <dbReference type="OrthoDB" id="10602568at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="143"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="167"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="332" mass="36592" checksum="22CAC8311B0606DF" modified="2017-02-15" version="1">MPTIKNVRTLMEQQPSPGMVKTRVSRDVQNKLGRWLEFIEGDLFDQIKKMHENFTVEGIKDFIHWMHNKSMHITTTLNTSPDLKDKAFLREALESWDKFTLSILDSSVEAYVNNHMLGNNGSIGAFPNTSVALSNNSSTTGASLPTTLSPTNSSSFPGTTFSHDLEATSSATSVSSTEHHGSNNITNSTVSSEQNVITLPDISLETVTTPTSNVLPSLPAESSGMSSAVCSTFLCGPTIAAFSVPLVLLGSVLCFVLLYKHTPLGSLLGRDNKKKEKGKKRLREMPKHNIENSSETLEETKAKRSRLDRFLRAFGYDKNFPYIDEETGKENI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSP3</accession>
    <name>A0A1J1GSP3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00274700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528358.1">
        <property type="nucleotide sequence ID" value="XM_028671735.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSP3"/>
    <dbReference type="GeneID" id="39731279"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00274700"/>
    <dbReference type="OrthoDB" id="392617at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="630"/>
            <end position="653"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="726" mass="89140" checksum="A46732C4E04F7998" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT23</accession>
    <name>A0A1J1GT23_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00020700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528249.1">
        <property type="nucleotide sequence ID" value="XM_028671614.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT23"/>
    <dbReference type="GeneID" id="39728729"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00020700"/>
    <dbReference type="OMA" id="FSEYSYY"/>
    <dbReference type="OrthoDB" id="371048at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="426" mass="50751" checksum="10A0713CCDC125D2" modified="2017-02-15" version="1">MNFHLNIFEEIEAILEKCNNETYLKIVKIIDYVVKNYTDTNNEIQKKNVLKKKKNKNNINESNSIKNYFKVLKKESTKITDDNVDQKNDYNSIIKKNSVSIINVFFFYGNFNVVIIIYYVIFKLKLFNSDLFINDNTNNEDYIIYKNKNIIHIMCSKLNSQSLNGINEIINEILATKLNSFKIFILESFDNLNEQYRRIFMNKITKSTNLIFIHSSIYLNDIFLNNCLYIRIAKPNRISFNNYILSMIEKKYKINNFNEKKEYLLNVLKNCNFDLTLILTIIYLIQLNNFPDISKIIKLIVNTNIKKLIKIIHKCIISNNCLFLIRNILYNILETYNFDIHTFLNTLCKNLTSFHKNDDNYKKEIYSLFSEYSYFCSLHDNHICSLENLCSKIILIEKKYVNTLNEKDIMEENNELNINLNMIEYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTL2</accession>
    <name>A0A1J1GTL2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00303800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAM154 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528634.1">
        <property type="nucleotide sequence ID" value="XM_028672041.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731571"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00303800"/>
    <dbReference type="OrthoDB" id="386544at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005879">
        <property type="term" value="C:axonemal microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005814">
        <property type="term" value="C:centriole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036126">
        <property type="term" value="C:sperm flagellum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033336">
        <property type="entry name" value="SAXO1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31516">
        <property type="entry name" value="STABILIZER OF AXONEMAL MICROTUBULES 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31516:SF17">
        <property type="entry name" value="STABILIZER OF AXONEMAL MICROTUBULES 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="616"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="681"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="721"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1111"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="498"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="565"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1158"/>
            <end position="1213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="618"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="632"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="728"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="745"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="755"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="841"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="907"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="917"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="971"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1117"/>
            <end position="1151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2010" mass="249717" checksum="C008345DE7F2D5E3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTL6</accession>
    <name>A0A1J1GTL6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00204200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527461.1">
        <property type="nucleotide sequence ID" value="XM_028670738.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTL6"/>
    <dbReference type="GeneID" id="39730569"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00204200"/>
    <dbReference type="OMA" id="RTDFYCW"/>
    <dbReference type="OrthoDB" id="76265at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="396" mass="46467" checksum="7E9D9F5CAD74D63B" modified="2017-02-15" version="1">MDVEWDNETINKFYNYLFELINYEKCLELEKDIRIETGTESVLNINSQLNENANNKINICTYKFKKNEDDIVGEILDNEKQEENIKNSIPLLTKKAFIIYTNVIDKAKSEGTNSINLETDHFLRTDIFKLVFNKYIIYNTKVKIKEIHCKNTKNIVSLANPLNIKDYDLNKINSETIANLMNNNVGIQTNFMGKECMKLIYDELIFIEYNNQFNEFSREYRNIRTDFYCWTYISSLDREKQKGLLKLLKELSLIPYELNKKANLSLQVCTLFQFLYFCPNKSFLKKHSEGGYGKLDNGKKITCIYIPLVHSNNDIEIKIYNNEDNLNEPNKINNNDTNTNLLNKMDNTPIKIIKPESDSLIFLQTRNISYEIPKTKNKFFIVNLWISGPASLEKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTP4</accession>
    <name>A0A1J1GTP4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00181100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527240.1">
        <property type="nucleotide sequence ID" value="XM_028670493.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTP4"/>
    <dbReference type="GeneID" id="39730338"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00181100"/>
    <dbReference type="OMA" id="EPWGDSQ"/>
    <dbReference type="OrthoDB" id="371209at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="104" mass="12447" checksum="6D6E9271DF3D69FC" modified="2017-02-15" version="1">MFSLKYFFYNLAWIALYHNNIKDNSSLIYPIKSYNSVNQRILRLDTPKPWGNSQTYEISRVNEDGNIVTTVYNREGQELYFYITKKRDNGNRGRNSRVRRGNRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTQ7</accession>
    <name>A0A1J1GTQ7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mitochondrial ribosomal protein S18, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00310400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528700.1">
        <property type="nucleotide sequence ID" value="XM_028672115.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTQ7"/>
    <dbReference type="GeneID" id="39731637"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00310400"/>
    <dbReference type="OMA" id="FIWRHTH"/>
    <dbReference type="OrthoDB" id="21463at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070181">
        <property type="term" value="F:small ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.640.10">
        <property type="entry name" value="Ribosomal protein S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001648">
        <property type="entry name" value="Ribosomal_bS18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036870">
        <property type="entry name" value="Ribosomal_bS18_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13479">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13479:SF40">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN BS18M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01084">
        <property type="entry name" value="Ribosomal_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46911">
        <property type="entry name" value="Ribosomal protein S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="359" mass="43472" checksum="9EA905C5245327E7" modified="2017-02-15" version="1">MILKHSFLYPLQNIVLKNKSILIFMRYNDSSKNISDTNLKKKLNTKLEDVKVTKESSCNALFDECLEELYKMKKKIDKESVEYDNSPVIEELNREEIKITKNIFERINKKKKHVSNLSYKDIYIDPYWNPFKEVNDLKNEITYEFNEYSKLASIVELKKQKRAIKKSLKEQYKLYNPYSEEYNNYFNLNIDKDEIICNDKSEKYWNPSFDRRKILNIKSPFTWRHTHILHNFIGENGLILPRKFNLTTRKQQIQIFKSICIARRMAIYPYDKKPNKDDLIPLMDPIQLLADELIHRYIELKDLRAQAIIKVMINKYPSLNYYKYFCYESKKKKKNQEKGEFSQILQKYKKNYYENSFNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTY8</accession>
    <name>A0A1J1GTY8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein phosphatase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00313200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528727.1">
        <property type="nucleotide sequence ID" value="XM_028672145.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731665"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00313200"/>
    <dbReference type="OMA" id="RTWKAVC"/>
    <dbReference type="OrthoDB" id="60843at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039123">
        <property type="entry name" value="PPTC7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320:SF1">
        <property type="entry name" value="PROTEIN PHOSPHATASE PTC7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="2">
        <location>
            <begin position="638"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1120"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1258"/>
            <end position="1290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1123"/>
            <end position="1134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1290" mass="148388" checksum="2095459F3F3FFE9D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU12</accession>
    <name>A0A1J1GU12_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00321700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000048">
        <property type="protein sequence ID" value="CRG96004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528812.1">
        <property type="nucleotide sequence ID" value="XM_028672240.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU12"/>
    <dbReference type="GeneID" id="39731750"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00321700"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="159" mass="19144" checksum="9679020D6D547DE8" modified="2017-02-15" version="1" fragment="single">EGNTEGKKPTNAEGCLKECPLDNEKNKSMDPDLYKNPYKYWLMFKVPKFWDRYENETSGMDPIWKVKKWNAEFIKISNKKFNDLYSIIRRDIPDKEKKEKTDSFMNEFDSEFEKFLFKCKQEMGDNKTESESKKEQGKIKKENNKSNTLKFLFCRFDNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU74</accession>
    <name>A0A1J1GU74_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fam-h protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00322100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000049">
        <property type="protein sequence ID" value="CRG96007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528815.1">
        <property type="nucleotide sequence ID" value="XM_028672243.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU74"/>
    <dbReference type="GeneID" id="39731753"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00322100"/>
    <dbReference type="OMA" id="IYEQINI"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022139">
        <property type="entry name" value="Fam-L/Fam-M-like_plasmodium"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12420">
        <property type="entry name" value="DUF3671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="199"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="106"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="228" mass="26797" checksum="3412CD9A4F36D10F" modified="2017-02-15" version="1">MRDYINSNFILNSRCNSHTEENFVIEDISTLKIYRTRGKINKLFFFIKISLFTLLIWILLYCENYNYRSWNDKYILKNILDLGSKRSLAEGKEVIEPKNEELKVSSLNIQTNLEEINTKIEKMELKEEEKDKKEIIKIENENVVEIKEERNKKVNILNLMQKCKSFLSILNMPTILLLPILSMALSITALFKSDEDNKYLHASNIVTSLYLVLNSILLLYLKSNSNNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU77</accession>
    <name>A0A1J1GU77_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Methionine aminopeptidase 2</fullName>
            <shortName evidence="9">MAP 2</shortName>
            <shortName evidence="9">MetAP 2</shortName>
            <ecNumber evidence="9">3.4.11.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Peptidase M</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00306100</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9 10">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="9">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="9">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="9">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="9"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528657.1">
        <property type="nucleotide sequence ID" value="XM_028672067.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU77"/>
    <dbReference type="GeneID" id="39731594"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00306100"/>
    <dbReference type="OMA" id="GNGWVYD"/>
    <dbReference type="OrthoDB" id="7848262at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004239">
        <property type="term" value="F:initiator methionyl aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01088">
        <property type="entry name" value="MetAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000370">
        <property type="entry name" value="Methionine aminopeptidase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.230.10:FF:000015">
        <property type="entry name" value="Methionine aminopeptidase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03175">
        <property type="entry name" value="MetAP_2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050247">
        <property type="entry name" value="Met_Aminopeptidase_Type2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002468">
        <property type="entry name" value="Pept_M24A_MAP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018349">
        <property type="entry name" value="Pept_M24A_MAP2_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00501">
        <property type="entry name" value="met_pdase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45777">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45777:SF2">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01202">
        <property type="entry name" value="MAP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9 10" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9 10" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M24" evidence="12">
        <location>
            <begin position="263"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="50"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="66"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="106"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="124"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="326"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="346"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="357"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="357"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="426"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="434"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="460"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="555"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="555"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG95849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="574" mass="66459" checksum="9B184E9F52EB1FA0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU86</accession>
    <name>A0A1J1GU86_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein SOC3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00199800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527416.1">
        <property type="nucleotide sequence ID" value="XM_028670689.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU86"/>
    <dbReference type="GeneID" id="39730524"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00199800"/>
    <dbReference type="OMA" id="KYTYQIM"/>
    <dbReference type="OrthoDB" id="391179at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="9"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="279"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="467" mass="56419" checksum="9F4928F5E8A23F85" modified="2017-02-15" version="1">MKNQNNDKLTNLKDLLPFYKKDNEKLNENTEGIVYSVKKKFNFIKEKGETTLHKYEHTKKNLELLNRELKLNKISLGQQKIEYEELKTKNEDILSKFENLKHSKYTYQIMLQRVKKEKKMLYFYLNSLERTVNSLKNNEKQLHNNIQKITSENKNLRKSIDEKKVEIIKAKNKNEEILKYMNVNKEHSNILRIRREMINEYKNNKLNNADISLMIQEKKKFKKLLIYYMLYNNYLKLNASNIFENASNIYATISKLREATGVTDIYDINQKFLDIENKKNLLQKEEEISQKKLEDAIKEYMKLNNEIINTFSEDKKILKKKILNEKERISEDIYELYKLVFSSEKELEDINIKLDKIKKFLEKQNDYFYSVNMEDKIEFHSNEDMLQYIKNLKLTIEILMKITQKNRENGNISRSYKSLEFLEIINLYKNVDFHKNMCRVEDSQDLDNTIKLGFFFFFFFFLKLLII</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU98</accession>
    <name>A0A1J1GU98_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Bis(5'-adenosyl)-triphosphatase</fullName>
            <ecNumber evidence="7">3.6.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00308500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>P(1),P(3)-bis(5'-adenosyl) triphosphate + H2O = AMP + ADP + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13893"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58529"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.1.29"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.29" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528681.1">
        <property type="nucleotide sequence ID" value="XM_028672094.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU98"/>
    <dbReference type="GeneID" id="39731618"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00308500"/>
    <dbReference type="OrthoDB" id="680339at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047710">
        <property type="term" value="F:bis(5'-adenosyl)-triphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01275">
        <property type="entry name" value="FHIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.428.10:FF:000011">
        <property type="entry name" value="Fragile histidine triad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051884">
        <property type="entry name" value="Bis(5'-adenosyl)-TPase_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039383">
        <property type="entry name" value="FHIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019808">
        <property type="entry name" value="Histidine_triad_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46243">
        <property type="entry name" value="BIS(5'-ADENOSYL)-TRIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46243:SF1">
        <property type="entry name" value="BIS(5'-ADENOSYL)-TRIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00892">
        <property type="entry name" value="HIT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="8">
        <location>
            <begin position="20"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-AMP-histidine intermediate" evidence="3">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="108"/>
            <end position="111"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for induction of apoptosis" evidence="5">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR639383-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR639383-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR639383-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG95873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="201" mass="23615" checksum="18BF0F9DDE420F15" modified="2017-02-15" version="1">MEKYEKILEYLEYNKNRSCDKYEFGMHEIDKREVFITTKHSYGFVNNKPILPGHILLTTLKKKKKYIDLDVEEIVDINLLSNFMCYIMGKLFNTTSFSIAIQDGKEAGQTVEQVHIHIIPRKSSDYKNNDNIYKDLNKINSGYGRNIICDSCQHSINVFSHIPIEENFKLEEFNISIRSIEEMEKEASLIKSYIHNFSLQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUD5</accession>
    <name>A0A1J1GUD5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00328800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000057">
        <property type="protein sequence ID" value="CRG96074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528879.1">
        <property type="nucleotide sequence ID" value="XM_028672315.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUD5"/>
    <dbReference type="GeneID" id="39731817"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00328800"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="99" mass="11695" checksum="843B8EE7CFAE6D64" modified="2017-02-15" version="1">MNSAPNHLKELPKKYEKLSTLKNNSYNGKNNYIHNLFNNRNVAFNNNYFMENKYMNKTHEFNVTRLCFGMQNNQDLYSEDSGYNDDYDASEYEIGDGNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV00</accession>
    <name>A0A1J1GV00_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00253300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527941.1">
        <property type="nucleotide sequence ID" value="XM_028671272.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV00"/>
    <dbReference type="GeneID" id="39731061"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00253300"/>
    <dbReference type="OMA" id="GKCTHHG"/>
    <dbReference type="OrthoDB" id="372448at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="357"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="391"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="540"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="842" mass="103002" checksum="25738065FFDC38E9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV11</accession>
    <name>A0A1J1GV11_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CRAL/TRIO domain-containing protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00354300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529130.1">
        <property type="nucleotide sequence ID" value="XM_028672593.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV11"/>
    <dbReference type="GeneID" id="39732073"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00354300"/>
    <dbReference type="OMA" id="ICSRMPQ"/>
    <dbReference type="OrthoDB" id="75724at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46818:SF1">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_125, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46818">
        <property type="entry name" value="DOMAIN-CONTAINING PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="146"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="49"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="301" mass="35632" checksum="38197350432C9F92" modified="2017-02-15" version="1">MMDDNSVSKYISKEVLAYEPTEEEIKFYHKHNHKSIRYIFCGKELDDFEKQKIKELKDYVNNLKLKEREKEKDEKSKNTILETYESLFKDTIFFDDNYVLRFLQGNEFIYEKCYNDMLRHIKWRQENLPIHLGEIKEFLNKGYCYIHGRDKQMHPIIIINCKNIISANTKDVLRVLYYWLEFCISKLLIEGKIEQWRVIIDLTSCGVLNIPISTLKDISRNLSCNYRSRLSKMLVLSAPLVVTGIWHMLKSIIPVVTQQKITITSSETEKKLLDQVQLDQLEKKFGGICNNATKFDEPILP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV49</accession>
    <name>A0A1J1GV49_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00358900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529170.1">
        <property type="nucleotide sequence ID" value="XM_028672637.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV49"/>
    <dbReference type="GeneID" id="39732119"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00358900"/>
    <dbReference type="OMA" id="YRNLMNY"/>
    <dbReference type="OrthoDB" id="375087at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="254" mass="29443" checksum="46AA901973B2FFAE" modified="2017-02-15" version="1">MNMDMAYSMRNVMNSARNIEEPKYDMNTVDLANNTMNTNYLMNGAVLTNAYNNDFMINREKYPADMISQLKLEQALKNYNNTMPMNSVTIQDPNDSISVHGMKTNLDTTGFESYRNLMNYNNTQNTIQANQIPINLDDYNNSDAMYVNASTGDKFSAEYINNLPTTDPDTILYSNNFKIPNGNFNTMMHNNYNNIPYSMPIFENMNNPQMYMQHMNQKQTMNIPLPNMEHKTSIRKIPAVTKRRIKPKKFFPCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV75</accession>
    <name>A0A1J1GV75_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00260500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528013.1">
        <property type="nucleotide sequence ID" value="XM_028671352.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731134"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00260500"/>
    <dbReference type="OMA" id="KIEYYDY"/>
    <dbReference type="OrthoDB" id="377692at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1361"/>
            <end position="1389"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="244"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1367"/>
            <end position="1382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2679" mass="322944" checksum="68A3247945F5012E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVB5</accession>
    <name>A0A1J1GVB5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00237600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527792.1">
        <property type="nucleotide sequence ID" value="XM_028671107.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVB5"/>
    <dbReference type="GeneID" id="39730904"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00237600"/>
    <dbReference type="OMA" id="KRICNQQ"/>
    <dbReference type="OrthoDB" id="444868at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="78" mass="9514" checksum="856207539AFBDF34" modified="2017-02-15" version="1">MFKLIFNSSPYLYSLKKRGILKKNFLRIQDKLICNQHTPLHIYNATKYSKKSMNHRLFYINWLFVFLFLDTCNNHLDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVH6</accession>
    <name>A0A1J1GVH6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">XRN2-binding (XTBD) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00352600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529113.1">
        <property type="nucleotide sequence ID" value="XM_028672574.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVH6"/>
    <dbReference type="GeneID" id="39732056"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00352600"/>
    <dbReference type="OMA" id="YLSCTYS"/>
    <dbReference type="OrthoDB" id="332938at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021859">
        <property type="entry name" value="XTBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11952">
        <property type="entry name" value="XTBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51827">
        <property type="entry name" value="XTBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XRN2-binding (XTBD)" evidence="1">
        <location>
            <begin position="21"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="91" mass="11154" checksum="FCF6A150835AB6E0" modified="2017-02-15" version="1">MDNQENLYENITTEEKEVLAEAETKREWESDGQWLKRREFLLKMLNYHKRNNIKIDVDKFSKMGHIFYNIKYLSCTYSNQIHDEIKKYEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVK7</accession>
    <name>A0A1J1GVK7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00416700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529390.1">
        <property type="nucleotide sequence ID" value="XM_028672882.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVK7"/>
    <dbReference type="GeneID" id="39732698"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00416700"/>
    <dbReference type="OrthoDB" id="340921at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013176091" description="PH domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="298" mass="34778" checksum="BC4FF02568413A27" modified="2017-02-15" version="1">MNSIKLFFCVCLVKVCLSRCNSIFFNKNVDKWTKELLKMPTNEYNNLNELNELTDRKFCGKSLKHLAGLILDKSDKEAKLIIEGSIISNKLILKMGNIKEKEININEIILPIETLSNKCINIRQMKEVDSTILCLGNKVLRNFWINSITDAVLCKMTKINGKLPEFNYEEEKEENNEEINEKKNNEKEESNEEESNDEESNEEKNKSKNKKEIDEAKKKIINEEFDEEDENEEKGLKLRIAKSKFGYPQVKINGKNIEDIKKKESLKKIPKSQNELKNLQNEKYEENLDNDTDIDETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVL3</accession>
    <name>A0A1J1GVL3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GTPase activator, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00416500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529388.1">
        <property type="nucleotide sequence ID" value="XM_028672880.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVL3"/>
    <dbReference type="GeneID" id="39732696"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00416500"/>
    <dbReference type="OMA" id="HPNLYEH"/>
    <dbReference type="OrthoDB" id="294251at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF9">
        <property type="entry name" value="GTPASE ACTIVATING PROTEIN AND CENTROSOME-ASSOCIATED, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="1"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="316"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="339" mass="40116" checksum="8084449AE2AA1E99" modified="2017-02-15" version="1">MIISKKFWEEEKEAPILNRNGNYVNEENSEHICKRVEHFYEIMLSYIKEDISVDLKEDCDDKEILRIIQLDAVRTFNSEENRKLLIKVLQSIYPITKDYHQGVSFISSFLLLFLEPKEVVKIIVGLHKYYLSGYFKAMPKAYVRDSRVFLNILKHFHPNLYEHIKNLITPEAFVSKWFIGLNVHVLTFESLLLFFEHLLKEGEIFLFKYSIGLCRALEHELMSTDDVSRILALLRLDKKIFPNDYKESDNQEIGEFFMNIIYNSLKVDMTGINLDKLREEASEQMRIEEERRKQFEMERDLTDDEIIFSDEENDSQNDSQSDSQNDSQNDSQNDSQSDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVR1</accession>
    <name>A0A1J1GVR1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00363600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529217.1">
        <property type="nucleotide sequence ID" value="XM_028672690.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732166"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00363600"/>
    <dbReference type="OMA" id="FRKANTN"/>
    <dbReference type="OrthoDB" id="372104at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1652"/>
            <end position="1685"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="33"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1656"/>
            <end position="1685"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2870" mass="343205" checksum="AFEFBE423D9F5C47" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVV9</accession>
    <name>A0A1J1GVV9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00368500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529265.1">
        <property type="nucleotide sequence ID" value="XM_028672742.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732215"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00368500"/>
    <dbReference type="OMA" id="CYGRFLP"/>
    <dbReference type="OrthoDB" id="386383at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1384"/>
            <end position="1456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3145"/>
            <end position="3197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3256"/>
            <end position="3284"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1240"/>
            <end position="1271"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1855"/>
            <end position="1914"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2462"/>
            <end position="2516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1388"/>
            <end position="1446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="3269"/>
            <end position="3281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3303" mass="393520" checksum="1C637C3BF8AD2609" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW09</accession>
    <name>A0A1J1GW09_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GPN-loop GTPase 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00260800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Binds to RNA polymerase II (RNAPII).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the GPN-loop GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528016.1">
        <property type="nucleotide sequence ID" value="XM_028671356.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW09"/>
    <dbReference type="GeneID" id="39731137"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00260800"/>
    <dbReference type="OMA" id="NYCKLMK"/>
    <dbReference type="OrthoDB" id="5839at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004130">
        <property type="entry name" value="Gpn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231:SF7">
        <property type="entry name" value="GPN-LOOP GTPASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231">
        <property type="entry name" value="XPA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03029">
        <property type="entry name" value="ATP_bind_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="400" mass="47225" checksum="C4C7C427068A5A56" modified="2017-02-15" version="1">MKYGQVVVGPAGSGKTNYCKLMKEFMRIKKRNCYVINLDSASEEYYYERKKKPMNTTSSIEKELTDIYDTIYDIDIRNYVEVNSLMEEQMLGPNCALLKSVELLYENSYILEDELNNYDDDDNYFIIDTPGQIELYTHTDYFKKILNIFTNQNIRLIIVFLIDISFISSNTKLLSAYLTSLSTMINFELPHINILTKCDLMVSKNYYEEFKKFKNNNNFFFQKQLYKKINKKIKTFKDIQNNIEDYNDNDSFLNELEFVNNKKSFKDEYILCSDYENKSISGYSSSNISEKNASSMSNTSEHSSVFYEENEEQIYKKNFEKLNDILSLDPHDIIIRANKCMSKKYYKLNNAFAHIIEDFNLVSFLPLNIYDDDNVDFIINSIDMIIQYGEDKDVNDNYDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW50</accession>
    <name>A0A1J1GW50_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ubiquitin-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00435000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529572.1">
        <property type="nucleotide sequence ID" value="XM_028673083.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732882"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00435000"/>
    <dbReference type="OMA" id="PLYFTHM"/>
    <dbReference type="OrthoDB" id="428577at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071818">
        <property type="term" value="C:BAT3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051787">
        <property type="term" value="F:misfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15204">
        <property type="entry name" value="LARGE PROLINE-RICH PROTEIN BAG6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15204:SF0">
        <property type="entry name" value="LARGE PROLINE-RICH PROTEIN BAG6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="679"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="718"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="3">
        <location>
            <begin position="6"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="856"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="918"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="857"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="918"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="937"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="961"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="980"/>
            <end position="1000"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1312" mass="154752" checksum="F325A6D27F003565" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW60</accession>
    <name>A0A1J1GW60_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytoadherence linked asexual protein 3.2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00001800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528064.1">
        <property type="nucleotide sequence ID" value="XM_028671408.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728540"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00001800"/>
    <dbReference type="OMA" id="KNKMSTY"/>
    <dbReference type="OrthoDB" id="369952at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020035">
        <property type="term" value="P:adhesion of symbiont to microvasculature"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005553">
        <property type="entry name" value="CLAG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03805">
        <property type="entry name" value="CLAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012227312" evidence="3">
        <location>
            <begin position="25"/>
            <end position="1403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="245"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1331"/>
            <end position="1373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1347"/>
            <end position="1359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1403" mass="167184" checksum="CB24FA1AD0102C20" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWI2</accession>
    <name>A0A1J1GWI2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF2423 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00425700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529481.1">
        <property type="nucleotide sequence ID" value="XM_028672983.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWI2"/>
    <dbReference type="GeneID" id="39732789"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00425700"/>
    <dbReference type="OMA" id="KMIDDMH"/>
    <dbReference type="OrthoDB" id="439961at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019434">
        <property type="entry name" value="DUF2423"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10338">
        <property type="entry name" value="YBL028C_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2423" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="151" mass="18002" checksum="425F5CF4D2338B59" modified="2017-02-15" version="1">MAKGLRSKVKRRFRTIKRVHVNEVIEKPNLKKLNNKIKLMLNNKNIYEDLIKPPNKFLYPEDERAVIPQHKVTKKIDFRSEALPLSGLVTVGNRRKYSLNEKIELKNEMGNNPNFYDNIEVSKIIDDMHKRSREVMKKINKKEDKNEKRDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWR6</accession>
    <name>A0A1J1GWR6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Calcium-dependent protein kinase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00295400</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528557.1">
        <property type="nucleotide sequence ID" value="XM_028671956.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWR6"/>
    <dbReference type="GeneID" id="39731487"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00295400"/>
    <dbReference type="OrthoDB" id="193931at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05117">
        <property type="entry name" value="STKc_CAMK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:001036">
        <property type="entry name" value="Calcium-dependent protein kinase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050205">
        <property type="entry name" value="CDPK_Ser/Thr_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24349">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="22"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG95749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="285" mass="33446" checksum="9AD9837BC32D0C62" modified="2017-02-15" version="1">MGNTFNKLIKNYSNSEKKKNEYKLGKVLGCGSFGVVRECINKETKEVYAVKIIKKKKKHKKNCNFEKMVKNEIKYLSIMSHENIIKFKDFFEDKKKFYIVLEKCEGGELFYKIVKNKCLMENESALIVRQICCALEYLHSNNIIHRDIKAENFLFKNKNTKNIKLIDFGMAKKVNCEYLTELCGSPHYISPELIRKKYTISSDIWALGVMVFFMLTGKYPFEGKNTPKVVDEILNKNINWKSKEFSSLSIEAVDFLKKLLERNEKKRLTAYQALNHPWIKSQKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWS6</accession>
    <name>A0A1J1GWS6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00267300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000036">
        <property type="protein sequence ID" value="CRG95470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528280.1">
        <property type="nucleotide sequence ID" value="XM_028671649.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWS6"/>
    <dbReference type="GeneID" id="39731202"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00267300"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="205" mass="24756" checksum="C9CAED28C0B16937" modified="2017-02-15" version="1">MKTLILFLKITTFLLLIWMYHCFYNGDSYKTLIDKNRLQIRNELKYERVLTEGDTAGEKQTYAEGCQEECTIEEKKKKWKNPLKRQKPYDRWQKVINPTLFERFKNETSGMDPKWINEKWNNEWNNISANKVDELSSIYMRNIPKNEKEKLMLTVKGELFELFVKFLDECKKEMRGNKTESESQKEMIDSKTESEYKIEMRDNKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWS8</accession>
    <name>A0A1J1GWS8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00459100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529814.1">
        <property type="nucleotide sequence ID" value="XM_028673353.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWS8"/>
    <dbReference type="GeneID" id="39733124"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00459100"/>
    <dbReference type="OMA" id="IPFQHGR"/>
    <dbReference type="OrthoDB" id="341300at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42663:SF6">
        <property type="entry name" value="HYDROLASE C777.06C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42663">
        <property type="entry name" value="HYDROLASE C777.06C-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="2">
        <location>
            <begin position="258"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="216"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="409" mass="47806" checksum="6A20D77DE7333E29" modified="2017-02-15" version="1">MIKENGIIFLGTGGSSSTPKLSHVFKNSKKILNKNKNSLSKLELKKEDYENIDKFVDELASKSLDCIDELNNLYLKKLYSDYPNMECYTCFDALNNDSKNKRNNISLLLKSNNSYVLIDVGKTFRDNMVLISHSHTDALNGIDDLRDLQDFNKTMYDDLYYYTPKKIIDIYLNEVTYERLLSGYAYLAQKRSENIFYSKIPALNIFILKDEKYNKIMRNDNVLSELKEESDKLENNIPIEKDIDRIDEKKINKDDDNTSVNIHTYDLKDEYGFIYSKFDNDKIIRFIPFEHGKNYICVGYIIGKDKKLVYISDCSNLSSYILNYIKNFEPIEILIIDALFYTRKHYSHFSLHQSIKIALLIKPKKVYFVGMSCAIEHNITNLFLQKLSKKYPDTSFSLAHDGLFIPFDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWT0</accession>
    <name>A0A1J1GWT0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pre-mRNA-splicing factor 18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00435600</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PRP18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529577.1">
        <property type="nucleotide sequence ID" value="XM_028673090.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWT0"/>
    <dbReference type="GeneID" id="39732888"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00435600"/>
    <dbReference type="OMA" id="SFAQVRW"/>
    <dbReference type="OrthoDB" id="10261918at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071021">
        <property type="term" value="C:U2-type post-spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000350">
        <property type="term" value="P:generation of catalytic spliceosome for second transesterification step"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.940.10:FF:000004">
        <property type="entry name" value="Pre-mRNA-splicing factor 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.940.10">
        <property type="entry name" value="Functional domain of the splicing factor Prp18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.110">
        <property type="entry name" value="Pre-mRNA processing factor 4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004098">
        <property type="entry name" value="Prp18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014906">
        <property type="entry name" value="PRP4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036285">
        <property type="entry name" value="PRP4-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039979">
        <property type="entry name" value="PRPF18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13007">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13007:SF19">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02840">
        <property type="entry name" value="Prp18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08799">
        <property type="entry name" value="PRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00500">
        <property type="entry name" value="SFM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47938">
        <property type="entry name" value="Functional domain of the splicing factor Prp18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158230">
        <property type="entry name" value="PRP4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Pre-mRNA processing factor 4 (PRP4)-like" evidence="9">
        <location>
            <begin position="86"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="153"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG96774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="341" mass="40434" checksum="92E7232E5EEDC62E" modified="2017-02-15" version="1">MDLLDNFIKKKKEEIKEIKGNKRWFKQAELEEQKNKEINKFYEKENKKKKIEEYERLKKLNETLDLKHKKNSTDIDNEEINIEITLSNKQIIMLLRQLKEPIRLFGETDLQRYNRLKELKINKNELKINEQNVFGDVLRGRLKENSLDLIEDNLEDESDNTDSKDITNLKSSINEKQNDDKGNELDKEKIIYDWIKSTMKEWNEEIENDDNKKKIKQATYLQTHKDLKPLEKKLKQKTLEPDILEKIYNIVSCCQKRNFKAAHDAYMLLAIGNAAWPMGVTMVGIHERAGRSKIFTSEVAHILNDETTRKYIQMIKRLLSFCQRKYCTNPSEAVNLSTIHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX85</accession>
    <name>A0A1J1GX85_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DIX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00282900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528440.1">
        <property type="nucleotide sequence ID" value="XM_028671826.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX85"/>
    <dbReference type="GeneID" id="39731362"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00282900"/>
    <dbReference type="OrthoDB" id="1717591at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031982">
        <property type="term" value="C:vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030276">
        <property type="term" value="F:clathrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072318">
        <property type="term" value="P:clathrin coat disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072583">
        <property type="term" value="P:clathrin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038207">
        <property type="entry name" value="DIX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23172">
        <property type="entry name" value="AUXILIN/CYCLIN G-ASSOCIATED KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23172:SF19">
        <property type="entry name" value="J DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="390"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="522" mass="61883" checksum="715A3CA8B9E0A686" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXN1</accession>
    <name>A0A1J1GXN1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00325900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000053">
        <property type="protein sequence ID" value="CRG96045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528853.1">
        <property type="nucleotide sequence ID" value="XM_028672285.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXN1"/>
    <dbReference type="GeneID" id="39731791"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00325900"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="345" mass="41352" checksum="FB6A75E2C4BA7DA9" modified="2017-02-15" version="1">MITLTLYIKITTFLLLIWMYKCFYNCYSYKTFIGKNILQTKNELKYERILTEGDIAGKMQTYSEGYLEECSLDNKKNKRENPVQNENPCDRWHRKTNPLLRKIFNKETSKMDPKWRDQKWNNEWNKISANKVNELSSIFHRSDISEEEKKKLIRNVKDELYVEFAKFSGECKKEMRDNKTESESKKEMIDNKTESESMKEMIDNKTESEYKKEMIDNKTESESMKEMIDNKRESEYKKEIIDNKTESESMKETIDNKAESESMKELINSKTESESKKEMRENRTESESTKEMRDNKAESESESEKEMRDNKTESESSKEQGTNEIKNYKKKIWELLIVLIILRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXY4</accession>
    <name>A0A1J1GXY4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00470100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529923.1">
        <property type="nucleotide sequence ID" value="XM_028673474.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXY4"/>
    <dbReference type="GeneID" id="39733234"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00470100"/>
    <dbReference type="OMA" id="MRIFHTE"/>
    <dbReference type="OrthoDB" id="3501663at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22642">
        <property type="entry name" value="IMIDAZOLONEPROPIONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22642:SF2">
        <property type="entry name" value="PROTEIN LONG AFTER FAR-RED 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydrolase 3" evidence="1">
        <location>
            <begin position="62"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="652" mass="76143" checksum="0BA29FEBBAF84026" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYC9</accession>
    <name>A0A1J1GYC9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="20">Endoplasmic reticulum oxidoreductin, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">PGAL8A_00350600</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 17">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">May function both as a monomer and a homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Lumenal side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the EROs family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529093.1">
        <property type="nucleotide sequence ID" value="XM_028672552.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYC9"/>
    <dbReference type="GeneID" id="39732036"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00350600"/>
    <dbReference type="OMA" id="CYKDRLH"/>
    <dbReference type="OrthoDB" id="269384at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016972">
        <property type="term" value="F:thiol oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007266">
        <property type="entry name" value="Ero1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037192">
        <property type="entry name" value="ERO1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12613:SF0">
        <property type="entry name" value="ERO1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12613">
        <property type="entry name" value="ERO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04137">
        <property type="entry name" value="ERO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017205">
        <property type="entry name" value="ERO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110019">
        <property type="entry name" value="ERO1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 18" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 17" id="KW-0274">FAD</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="19" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="430"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="16">
        <location>
            <position position="364"/>
        </location>
    </feature>
    <feature type="active site" evidence="16">
        <location>
            <position position="367"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="18">
        <location>
            <begin position="364"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR017205-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR017205-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR017205-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="CRG96288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="463" mass="54848" checksum="D176D5A971881BED" modified="2017-02-15" version="1">MKIPIFSFFFTLIFFGIFLKAKKFDVFLSYHKRISKKINEILLYFNIFEVQYPLSYINNEKILGLHMKDIEKDAYKVYPILKELKQKDYFRIFKVNLHISCKFLKISEKCKEMKKCSVCECDDDKIPYNFRTNEIEIIEDKLSNEDLKKTFTESKLYNDILGIYAPSNEGFLSYVDLVYNSPCFTAYEGKNIWDMIYKENCFINADRQCEEMNSFYKIISGMQSNIAVLSSEYYYLKNDNILEENKLNNKFSFDQYPKLNYDYSVSFFKEKIGLYPDRIENLYFTFAILLRAMCRLKSLFKQCKCNSGYEEDDKAAVKLLNELLENSYHSCSSKEFLEPLFPTQGKEILSKFKNITKILDCVPCVKCRLHGKLKTTALQIALVEGVSNEHIGSLERNEITALINALYYFADSIIIIHKFQERLKLRKTIFIFYLLSFLLFTFLIIYSVIFVTIRNYKKKRKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYL2</accession>
    <name>A0A1J1GYL2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Zinc finger (CCCH type) protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00511700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530345.1">
        <property type="nucleotide sequence ID" value="XM_028673942.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYL2"/>
    <dbReference type="GeneID" id="39733650"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00511700"/>
    <dbReference type="OrthoDB" id="369783at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="2">
        <location>
            <begin position="43"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="43"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="403" mass="46372" checksum="E794B9A85B82ED4A" modified="2017-02-15" version="1">MRGSYIRDGFKSQYRYSNGSDNNKIQNSFNRRTYYSKKNINKDKGAIFCPHYTLRGTCRFINDCKNLHNLKLVDTFFLQRSYIDCAIIVHGPNNEIYLFTSVSPYTINVWIFVPGEGSKEIDIKHLKKIEFELTEEEESYCYDKLKYNKKKKKKKRVLALLYAEECIFAGLDNGLIKIMHLPSSDSSTLFAHSDAIYSILCIDGIIISSCVNGEVKFWKYQESYLSFVTIKKIETKTKIYKMIEVISPKSLNTNNSNTEDSKYNRTLWVCGDSITIINLLNLQIVNKVKCKYGNVVSVIQYDANIITAMSEGKIIAYNLSGEDHFEMNTLPIYCMTGLTNNKNMPILIYGSTKALYTFSLPQFNPFGYLRDRESISLKYNLNDPDFILSLSGPYFIVIFSNGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYP2</accession>
    <name>A0A1J1GYP2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Signal recognition particle subunit SRP72</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00364000</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SRP72 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529221.1">
        <property type="nucleotide sequence ID" value="XM_028672694.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYP2"/>
    <dbReference type="GeneID" id="39732170"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00364000"/>
    <dbReference type="OMA" id="CFTYIYT"/>
    <dbReference type="OrthoDB" id="372133at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013699">
        <property type="entry name" value="Signal_recog_part_SRP72_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026270">
        <property type="entry name" value="SRP72"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14094">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14094:SF9">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE SUBUNIT SRP72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08492">
        <property type="entry name" value="SRP72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7" id="KW-0733">Signal recognition particle</keyword>
    <feature type="domain" description="Signal recognition particle SRP72 subunit RNA-binding" evidence="10">
        <location>
            <begin position="626"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="637"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="638"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="657"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="671"/>
            <end position="680"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG96416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="712" mass="85715" checksum="8FB9F5F0C28FD3E0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYX7</accession>
    <name>A0A1J1GYX7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Translational activator GCN1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00501400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530242.1">
        <property type="nucleotide sequence ID" value="XM_028673828.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733547"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00501400"/>
    <dbReference type="OMA" id="EMWPILL"/>
    <dbReference type="OrthoDB" id="5148094at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019887">
        <property type="term" value="F:protein kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23346:SF7">
        <property type="entry name" value="STALLED RIBOSOME SENSOR GCN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23346">
        <property type="entry name" value="TRANSLATIONAL ACTIVATOR GCN1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24987">
        <property type="entry name" value="HEAT_EF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1382"/>
            <end position="1404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1548"/>
            <end position="1574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="2038"/>
            <end position="2168"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1580"/>
            <end position="1607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1388"/>
            <end position="1397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1555"/>
            <end position="1574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="2046"/>
            <end position="2134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="2141"/>
            <end position="2166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="3281" mass="389999" checksum="45635631D08D2B0B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ13</accession>
    <name>A0A1J1GZ13_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nucleoside triphosphate hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00504600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530274.1">
        <property type="nucleotide sequence ID" value="XM_028673863.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ13"/>
    <dbReference type="GeneID" id="39733579"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00504600"/>
    <dbReference type="OMA" id="DDEMYIC"/>
    <dbReference type="OrthoDB" id="10263927at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33477">
        <property type="entry name" value="P-LOOP NTPASE DOMAIN-CONTAINING PROTEIN LPA1 HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33477:SF3">
        <property type="entry name" value="P-LOOP NTPASE DOMAIN-CONTAINING PROTEIN LPA1 HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="349" mass="41409" checksum="8B95AD37FCEB3CB0" modified="2017-02-15" version="1">MNKNGYNNLFIEDVIKRDIEIKKDFIKNVINFNSRIPLVKYEREGCEMHICSRYLFINNIFINVKKEGDKFKINFVNNDCSKLNDKNKTDNDILNENLLNSLFFKNNKNFVIIISGSSGCGKSTLSCLLGFFLKIKRILSTDIIREILRIYEVKNNKFLRFSTYESWKLTTYEEDEDEEEDESDKEVNDMHIREKINSENNNQIENENNIKKKLKERCIKNYLKQCELLFSYIDDIINDHIKKNESLIIEGVHVNSDIINKLTKKYPNKIIYFLVYISDRETSIQRFSNRCNESNDKVNKYIENFSYINDIQTYLLETSKFLSSTINYIENVNINKSLEKVLKIIYSFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ39</accession>
    <name>A0A1J1GZ39_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Golgi protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00350100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529088.1">
        <property type="nucleotide sequence ID" value="XM_028672547.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ39"/>
    <dbReference type="GeneID" id="39732031"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00350100"/>
    <dbReference type="OrthoDB" id="377580at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012859627" description="Golgi protein 2" evidence="3">
        <location>
            <begin position="21"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1006"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="653"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="205"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="660"/>
            <end position="672"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1042" mass="122900" checksum="9665A18504AECD04" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZA0</accession>
    <name>A0A1J1GZA0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">inositol-3-phosphate synthase</fullName>
            <ecNumber evidence="5">5.5.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00033100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:10716"/>
            <dbReference type="ChEBI" id="CHEBI:58401"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="5.5.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Polyol metabolism; myo-inositol biosynthesis; myo-inositol from D-glucose 6-phosphate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the myo-inositol 1-phosphate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.5.1.4" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530693.1">
        <property type="nucleotide sequence ID" value="XM_028674329.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZA0"/>
    <dbReference type="GeneID" id="39728854"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00033100"/>
    <dbReference type="OMA" id="VYVPMKE"/>
    <dbReference type="OrthoDB" id="2887at2759"/>
    <dbReference type="UniPathway" id="UPA00823">
        <property type="reaction ID" value="UER00787"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004512">
        <property type="term" value="F:inositol-3-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006021">
        <property type="term" value="P:inositol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000542">
        <property type="entry name" value="Inositol-3-phosphate synthase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002587">
        <property type="entry name" value="Myo-inos-1-P_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013021">
        <property type="entry name" value="Myo-inos-1-P_Synthase_GAPDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11510">
        <property type="entry name" value="MYO-INOSITOL-1 PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01658">
        <property type="entry name" value="Inos-1-P_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07994">
        <property type="entry name" value="NAD_binding_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015578">
        <property type="entry name" value="Myoinos-ppht_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0398">Inositol biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myo-inositol-1-phosphate synthase GAPDH-like" evidence="7">
        <location>
            <begin position="330"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="600" mass="69249" checksum="2070ED7DDDB6C4BD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZA1</accession>
    <name>A0A1J1GZA1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00036100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530723.1">
        <property type="nucleotide sequence ID" value="XM_028674362.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZA1"/>
    <dbReference type="GeneID" id="39728885"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00036100"/>
    <dbReference type="OMA" id="FKSMPYH"/>
    <dbReference type="OrthoDB" id="371157at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="153" mass="17729" checksum="C4F00406D4385EC6" modified="2017-02-15" version="1" fragment="single">LLQLFVLLSLTFCLLSFIILKRKNGPHILSKIKMYPFSFKDLIEVSLSTGTLTISILDIFLCYLYLLVALLIFLTAIFSVYKSLENPYMRDNDNINSFTLQFISVSFIGLYTISQISIFRTMPYHPLEYLGYIIKNIGDDILSIMKKVWNFLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZG9</accession>
    <name>A0A1J1GZG9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fam-h protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00377200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000119">
        <property type="protein sequence ID" value="CRG97966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530765.1">
        <property type="nucleotide sequence ID" value="XM_028674408.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZG9"/>
    <dbReference type="GeneID" id="39732302"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00377200"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="175" mass="20511" checksum="04582A350BF4ADAB" modified="2017-02-15" version="1">MFAFLILIFQYSNNISFESWNIKKISEGTFRLKAKRTLSENIFKKSKSESTENLLDALEKEEIKEKPDEMEKNLVKSKAQKSIFHSFNIPEPSETIVEILNENNVNKQKVTKCKKFIDSFLFSLISLSLPLYLVYLSHMEYDSKTNVNCEKRHFLMSYCILMISCLICLLYHKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZJ0</accession>
    <name>A0A1J1GZJ0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00429300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529517.1">
        <property type="nucleotide sequence ID" value="XM_028673023.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732825"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00429300"/>
    <dbReference type="OMA" id="CKNCENC"/>
    <dbReference type="OrthoDB" id="392823at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1120"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1153"/>
            <end position="1170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1765" mass="214685" checksum="8DEAD6941AEBEF10" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZR1</accession>
    <name>A0A1J1GZR1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA methyltransferase</fullName>
            <ecNumber evidence="6">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00373200</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529312.1">
        <property type="nucleotide sequence ID" value="XM_028672795.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZR1"/>
    <dbReference type="GeneID" id="39732262"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00373200"/>
    <dbReference type="OMA" id="IGCNCGV"/>
    <dbReference type="OrthoDB" id="540004at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017069">
        <property type="term" value="F:snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040031">
        <property type="term" value="P:snRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039772">
        <property type="entry name" value="Bin3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010675">
        <property type="entry name" value="Bin3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024160">
        <property type="entry name" value="BIN3_SAM-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12315:SF0">
        <property type="entry name" value="7SK SNRNA METHYLPHOSPHATE CAPPING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12315">
        <property type="entry name" value="BICOID-INTERACTING PROTEIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06859">
        <property type="entry name" value="Bin3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51515">
        <property type="entry name" value="BIN3_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Bin3-type SAM" evidence="8">
        <location>
            <begin position="162"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="58"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG96507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="460" mass="56179" checksum="D0F905AE095EADF4" modified="2017-02-15" version="1">MSCIFENIERNDFKRLKNYFKIPLKYQNYEYKLINKYKKKKKKIYLYGNFPNYYYERYKKKKIEKDEINIEKEEIKKENDEINIEKEEIKKENDEINIEKDEINIEKDEINIEKEEIKKEKDEINIEKDEIKENNNNNNSNNQSLSNLKKDKCIQNKNIIDDYRLTQIDNLIKDIFKDKIILDIGCNSGITTFLLSLKYKCKIVNGIDIDFSLINKNICLLKLFIEFILIYNNQKHILQFFLNNKNLHKIEKDIFLDLYFLYEDLKQERCKDKCEIKNLNIEINENRNKDKNRTFNESYSLIDDSNSLLENTHKYTFPLNIYFLCSNIFDKRFNKIENKYDIIICFSVLKWIHLNYGDNHIIIFFDLIHKMLKKDGYFILEYHNEIKYKIKKYERDFYKHKINLNYMHFDDIANGAYNNSCKLKLIHKTNFNVEEEQLKNKNKKKKLGMFNRSIRIYQKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZX4</accession>
    <name>A0A1J1GZX4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SURF1-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00415100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Probably involved in the biogenesis of the COX complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Mitochondrion inner membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SURF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529376.1">
        <property type="nucleotide sequence ID" value="XM_028672867.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZX4"/>
    <dbReference type="GeneID" id="39732682"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00415100"/>
    <dbReference type="OMA" id="YYYVICP"/>
    <dbReference type="OrthoDB" id="10040024at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002994">
        <property type="entry name" value="Surf1/Shy1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045214">
        <property type="entry name" value="Surf1/Surf4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23427">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23427:SF2">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02104">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="637"/>
            <end position="659"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="666" mass="80711" checksum="F15AE906ABE80728" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0K7</accession>
    <name>A0A1J1H0K7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PIR-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00377700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000141">
        <property type="protein sequence ID" value="CRG98099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530896.1">
        <property type="nucleotide sequence ID" value="XM_028674556.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0K7"/>
    <dbReference type="GeneID" id="39732307"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00377700"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009266">
        <property type="entry name" value="Adeno_E3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06040">
        <property type="entry name" value="Adeno_E3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="125" mass="13276" checksum="9607DDAD01C03069" modified="2017-02-15" version="1">MEKKKSEELSINQLPTTSSDSHTNSTISSINNTSDSPTTLSTNEINSTTALTNNSVSLLPTEQGGGLTSATCKGLFCGPAFVAFPVSLALLGGVLFFVLLYMYTPVGKFLGRDNPKKKKSKKKIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H190</accession>
    <name>A0A1J1H190_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00487800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530101.1">
        <property type="nucleotide sequence ID" value="XM_028673672.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H190"/>
    <dbReference type="GeneID" id="39733411"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00487800"/>
    <dbReference type="OrthoDB" id="372522at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="169" mass="19697" checksum="480676A016BEA7B2" modified="2017-02-15" version="1">MEHNNEEDIHNSSELKSQFEDKEKKKKESNKDINSNLIVCEEKNENNMESQVLNSRKEMPSIANLKENANIFAEHIAKQAKMKASEFISKNDRVQQEFSGIGMNTNQQNSMENNYINIKDEYVIINDSEDENQENLNEKQRKKKILIGAKPVMPTGDKELLEKLKQRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1K6</accession>
    <name>A0A1J1H1K6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PHF5-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00477600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PHF5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530000.1">
        <property type="nucleotide sequence ID" value="XM_028673560.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1K6"/>
    <dbReference type="GeneID" id="39733309"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00477600"/>
    <dbReference type="OMA" id="AYYCWEC"/>
    <dbReference type="OrthoDB" id="10248186at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005345">
        <property type="entry name" value="PHF5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13120">
        <property type="entry name" value="PHD FINGER-LIKE DOMAIN-CONTAINING PROTEIN 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03660">
        <property type="entry name" value="PHF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016468">
        <property type="entry name" value="PHF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="111" mass="12549" checksum="E119AF65387C305D" modified="2017-02-15" version="1">MAAKHHPDLIMCRKQPGIAIGRLCEKCDGKCPICDSYVRPYTLVRICDECNYGSYQGRCIICGGTGVSDAYYCKECCLCEKDRDGCPKIVNLGSAKTDLFYENKKYEFKKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2L9</accession>
    <name>A0A1J1H2L9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rhoptry protein 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00516300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530391.1">
        <property type="nucleotide sequence ID" value="XM_028673994.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2L9"/>
    <dbReference type="GeneID" id="39733696"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00516300"/>
    <dbReference type="OrthoDB" id="337624at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051590">
        <property type="entry name" value="Replication_Regulatory_Kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15375">
        <property type="entry name" value="ACTIVATOR OF S-PHASE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15375:SF27">
        <property type="entry name" value="DBF4-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="566"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="574"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1222" mass="144893" checksum="F679A7BC553293C4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3K8</accession>
    <name>A0A1J1H3K8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">BolA-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00037300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BolA/IbaG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530735.1">
        <property type="nucleotide sequence ID" value="XM_028674375.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3K8"/>
    <dbReference type="GeneID" id="39728897"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00037300"/>
    <dbReference type="OMA" id="VHAFSQK"/>
    <dbReference type="OrthoDB" id="4983at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045115">
        <property type="entry name" value="BOL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002634">
        <property type="entry name" value="BolA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036065">
        <property type="entry name" value="BolA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12735:SF27">
        <property type="entry name" value="BOLA-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12735">
        <property type="entry name" value="BOLA-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01722">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003113">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82657">
        <property type="entry name" value="BolA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="88" mass="10185" checksum="D6B97B0D99F9AC64" modified="2017-02-15" version="1">MKMHIQKIIEEKLSHVLKPTFLELIDKSCGCGTSFDAVIVSNNFANKKLLDRHRIVNDIIKEELQNIHAFSMKCHTPMEYDKIKNTSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3X2</accession>
    <name>A0A1J1H3X2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="5">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00062000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 5">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="5">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530980.1">
        <property type="nucleotide sequence ID" value="XM_028674649.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3X2"/>
    <dbReference type="GeneID" id="39729145"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00062000"/>
    <dbReference type="OrthoDB" id="360481at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="277"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG98183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1241" mass="147984" checksum="78454F952A681365" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H439</accession>
    <name>A0A1J1H439_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ORF79</name>
        <name evidence="1" type="ORF">PGAL8A_API03700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <geneLocation type="apicoplast" evidence="1"/>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="LN835293">
        <property type="protein sequence ID" value="CRG98247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009325474.1">
        <property type="nucleotide sequence ID" value="NC_031963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H439"/>
    <dbReference type="GeneID" id="30315774"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_API03700"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Apicoplast API"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0933">Apicoplast</keyword>
    <keyword evidence="1" id="KW-0934">Plastid</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG98247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="116" mass="14347" checksum="6CEF67A70D7B52C9" modified="2017-02-15" version="1">MINNIFLYSKSNKTKYKTYKIILIENYKIIKLGIYNPKLNIISCMYYKLLKYLKYNYILNKNLLKILLYKIKNNIREMTEWFIVFDLRSKKYLNISWVQIPFSLFNIKYYLIKNDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2012-05-16" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>H7CDZ3</accession>
    <name>H7CDZ3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Open reading frame 101</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ORF101</name>
        <name evidence="3" type="ORF">PGAL8A_API04400</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <geneLocation type="apicoplast" evidence="2"/>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Mol. Biol. Evol." volume="29" first="2095" last="2099">
            <title>The Plasmodium Apicoplast Genome: Conserved Structure and Close Relationship of P. ovale to Rodent Malaria Parasites.</title>
            <authorList>
                <person name="Arisue N."/>
                <person name="Hashimoto T."/>
                <person name="Mitsui H."/>
                <person name="Palacpac N.M.Q."/>
                <person name="Kaneko A."/>
                <person name="Kawai S."/>
                <person name="Hasegawa M."/>
                <person name="Tanabe K."/>
                <person name="Horii T."/>
            </authorList>
            <dbReference type="PubMed" id="22396524"/>
            <dbReference type="DOI" id="10.1093/molbev/mss082"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">A8</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">8A</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AB649424">
        <property type="protein sequence ID" value="BAL70763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LN835293">
        <property type="protein sequence ID" value="CRG98254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009325481.1">
        <property type="nucleotide sequence ID" value="NC_031963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="H7CDZ3"/>
    <dbReference type="GeneID" id="30315802"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_API04400"/>
    <dbReference type="OMA" id="IIKYDNY"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Apicoplast API"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0933">Apicoplast</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0934">Plastid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAL70763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="103" mass="12693" checksum="F22989BFF880B527" modified="2012-05-16" version="1">MKLNIIKYYYIKNKKLIFNNINKNFIFKKYIIIKLFFYEYINNKLKIFNFKGIFINNNSNNNIILLKYNNNDILFLYFYLNIFNLITILKLGKLNLNKIKFLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKV0</accession>
    <name>A0A1J1GKV0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00070500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525823.1">
        <property type="nucleotide sequence ID" value="XM_028674087.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKV0"/>
    <dbReference type="GeneID" id="39729230"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00070500"/>
    <dbReference type="OrthoDB" id="430536at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="130" mass="15596" checksum="A24A73FCC8557148" modified="2017-02-15" version="1">MRILKIKNFNLNYIKTSKFLFSGYTGKHISDKDLVKKSDDWYIEETNFCLGRVTKLRFSENDDMARRVLKIMDSQLSKMYTRMRDGTVIPFMSFYLNDVIDKPAPNHQFIEQPLIKWTWDEAYDEAYEEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKY1</accession>
    <name>A0A1J1GKY1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">PGAL8A_00075200</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DEAD box helicase family. DDX41 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525868.1">
        <property type="nucleotide sequence ID" value="XM_028675134.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKY1"/>
    <dbReference type="GeneID" id="39729277"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00075200"/>
    <dbReference type="OMA" id="FKTIWTL"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000449">
        <property type="entry name" value="Probable ATP-dependent RNA helicase DDX41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000657">
        <property type="entry name" value="Probable ATP-dependent RNA helicase DDX41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 18" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="17">
        <location>
            <begin position="201"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="15">
        <location>
            <begin position="232"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="16">
        <location>
            <begin position="427"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="50"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="114"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="12">
        <location>
            <begin position="201"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="54"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="73"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="CRG93046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="650" mass="74400" checksum="601640F91DD438CE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL92</accession>
    <name>A0A1J1GL92_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00087800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525996.1">
        <property type="nucleotide sequence ID" value="XM_028671311.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL92"/>
    <dbReference type="GeneID" id="39729402"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00087800"/>
    <dbReference type="OMA" id="MKSCAYS"/>
    <dbReference type="OrthoDB" id="376476at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="346" mass="40889" checksum="C021CF84F39F0E06" modified="2017-02-15" version="1">MAYKKQNYIEEQSLKKSAYLEFDDKEKIKDRSNVHVSIKEKQMRIAELLSSKKNDNFPKKSVDFTLSQKTESEYMDECLARRKQFSVTNADIANKLNNTLFSKITTSKNVSFSNSKNSSYMDEKSLLDKNEKSFKNKSISSLNNKISEDYKNKLSSVLLSRDKSHFLKNKDFEKKNSNDFPKTDYIAEDNSNNSHKNSKGDIDNKRKDLFKQLLSTYSNLQKIDHNQNRDKNTLQKLENEDENKNESITDKNLYLNENFSNYKNNQNTMDPPNIIKKKKIINFFSCFKNLKRKKYYKRKNNMKCNSPIKEKHLSKTEEKIDITCYEEENSISSNKRARSKFFFFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLL7</accession>
    <name>A0A1J1GLL7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00102600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526142.1">
        <property type="nucleotide sequence ID" value="XM_028672932.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLL7"/>
    <dbReference type="GeneID" id="39729551"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00102600"/>
    <dbReference type="OMA" id="KWINMEN"/>
    <dbReference type="OrthoDB" id="372449at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1227" mass="147102" checksum="0DE5F0336474B719" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLM5</accession>
    <name>A0A1J1GLM5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Dynein heavy chain, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PGAL8A_00095000</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Consists of at least two heavy chains and a number of intermediate and light chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynein heavy chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526066.1">
        <property type="nucleotide sequence ID" value="XM_028672088.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729474"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00095000"/>
    <dbReference type="OMA" id="CAWLRGL"/>
    <dbReference type="OrthoDB" id="424310at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005881">
        <property type="term" value="C:cytoplasmic microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008569">
        <property type="term" value="F:minus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007097">
        <property type="term" value="P:nuclear migration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.20:FF:000002">
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        <property type="entry name" value="Cytoplasmic dynein heavy chain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.2620:FF:000008">
        <property type="entry name" value="Dynein heavy chain, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000829">
        <property type="entry name" value="Dynein heavy chain, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.490.20:FF:000020">
        <property type="entry name" value="Dynein heavy chain, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.710:FF:000009">
        <property type="entry name" value="Dynein heavy chain-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1120:FF:000013">
        <property type="entry name" value="Dynein heavy chain-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002357">
        <property type="entry name" value="Glutathione S-transferase class-mu 26 kDa isozyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.280">
        <property type="match status" value="1"/>
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    <dbReference type="Gene3D" id="1.20.58.1120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.100">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.180.20">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.720">
        <property type="entry name" value="Region D6 of dynein motor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035699">
        <property type="entry name" value="AAA_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035706">
        <property type="entry name" value="AAA_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041658">
        <property type="entry name" value="AAA_lid_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042219">
        <property type="entry name" value="AAA_lid_11_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054354">
        <property type="entry name" value="DYNC2H1-like_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042222">
        <property type="entry name" value="Dynein_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043157">
        <property type="entry name" value="Dynein_AAA1S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041466">
        <property type="entry name" value="Dynein_AAA5_ext"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041228">
        <property type="entry name" value="Dynein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043160">
        <property type="entry name" value="Dynein_C_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024743">
        <property type="entry name" value="Dynein_HC_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024317">
        <property type="entry name" value="Dynein_heavy_chain_D4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004273">
        <property type="entry name" value="Dynein_heavy_D6_P-loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013602">
        <property type="entry name" value="Dynein_heavy_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013594">
        <property type="entry name" value="Dynein_heavy_tail"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042228">
        <property type="entry name" value="Dynein_linker_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10676:SF314">
        <property type="entry name" value="CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10676">
        <property type="entry name" value="DYNEIN HEAVY CHAIN FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12774">
        <property type="entry name" value="AAA_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12775">
        <property type="entry name" value="AAA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12780">
        <property type="entry name" value="AAA_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12781">
        <property type="entry name" value="AAA_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18198">
        <property type="entry name" value="AAA_lid_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08385">
        <property type="entry name" value="DHC_N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08393">
        <property type="entry name" value="DHC_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22597">
        <property type="entry name" value="DYN_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17852">
        <property type="entry name" value="Dynein_AAA_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18199">
        <property type="entry name" value="Dynein_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03028">
        <property type="entry name" value="Dynein_heavy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12777">
        <property type="entry name" value="MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-0243">Dynein</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-0505">Motor protein</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="14">
        <location>
            <begin position="1946"/>
            <end position="2089"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="14">
        <location>
            <begin position="2689"/>
            <end position="2843"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="14">
        <location>
            <begin position="3034"/>
            <end position="3198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="4552"/>
            <end position="4574"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="1141"/>
            <end position="1172"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="1634"/>
            <end position="1661"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="3295"/>
            <end position="3371"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="3508"/>
            <end position="3605"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="3876"/>
            <end position="3903"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG93244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="4909" mass="570527" checksum="3863B47A9ADEB6AE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLN7</accession>
    <name>A0A1J1GLN7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TTI1 C-terminal TPR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00099500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526111.1">
        <property type="nucleotide sequence ID" value="XM_028672588.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729519"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00099500"/>
    <dbReference type="OMA" id="LKGYIYY"/>
    <dbReference type="OrthoDB" id="372271at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057567">
        <property type="entry name" value="TPR_TTI1_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24181">
        <property type="entry name" value="TPR_TTI1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="845"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="965"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1141"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="domain" description="TTI1 C-terminal TPR" evidence="3">
        <location>
            <begin position="1349"/>
            <end position="1562"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="791"/>
            <end position="818"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1678" mass="204226" checksum="3A6F0426944FD6AF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMP4</accession>
    <name>A0A1J1GMP4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Pre-mRNA-splicing factor SLU7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00138700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in pre-mRNA splicing.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the SLU7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526503.1">
        <property type="nucleotide sequence ID" value="XM_028674920.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMP4"/>
    <dbReference type="GeneID" id="39729911"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00138700"/>
    <dbReference type="OMA" id="KYAWESQ"/>
    <dbReference type="OrthoDB" id="249612at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030628">
        <property type="term" value="F:pre-mRNA 3'-splice site binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021715">
        <property type="entry name" value="Slu7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039974">
        <property type="entry name" value="Splicing_factor_SLU7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12942:SF2">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR SLU7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12942">
        <property type="entry name" value="STEP II SPLICING FACTOR SLU7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11708">
        <property type="entry name" value="Slu7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5 7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Pre-mRNA-splicing factor SLU7" evidence="9">
        <location>
            <begin position="131"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF11708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG93681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="431" mass="51513" checksum="E6166595C03A3604" modified="2017-02-15" version="1">MNTKNVTREEKKKEMELNEARKAGKVEALKDEEGNEINPHMPQYIIKAPWYLNQTKPGLKHQRYKGTDKVKIEEERNKKIFLKNNKIQEFCKNCGSAAHKEKYCLERTRKKKINFMKKDNDDDFICVTQDLGYDGNRDRWVGYNSDNFEQIYREYEKIVEEKKKRKAEELKKKYEKKSIKKKKNLDENDDTKNDKSSSESETLEKCNDDLKDDLMETSAINAINKNEKSRNVARNLRIREDTAKYLYNLSLNSAFYDPKSRSMREDPFANISKNLSEENNYYKGENYYNNTDDAIESKKLEIFAWETYKRGENVHFNAQPTQLELLYKEFLEKKKKLIKKKQEDILKTYKCENLSKEFNDELIHSEIYTEYKPSDQIDPKRKKIKVLSKYEEDIYAFDHSSVFGSYYDKEKKKWGYKCCLSTNKFEKCLHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMW3</accession>
    <name>A0A1J1GMW3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Geranylgeranyl transferase type-2 subunit beta</fullName>
            <ecNumber evidence="8">2.5.1.60</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00131000</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21240"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11537"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57533"/>
            <dbReference type="ChEBI" id="CHEBI:86021"/>
            <dbReference type="EC" id="2.5.1.60"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the protein prenyltransferase subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.60" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526427.1">
        <property type="nucleotide sequence ID" value="XM_028674836.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMW3"/>
    <dbReference type="GeneID" id="39729835"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00131000"/>
    <dbReference type="OMA" id="AESHCGQ"/>
    <dbReference type="OrthoDB" id="5428259at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005968">
        <property type="term" value="C:Rab-protein geranylgeranyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004663">
        <property type="term" value="F:Rab geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02894">
        <property type="entry name" value="GGTase-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045089">
        <property type="entry name" value="PGGT1B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001330">
        <property type="entry name" value="Prenyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026873">
        <property type="entry name" value="Ptb1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774:SF11">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00432">
        <property type="entry name" value="Prenyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 8" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Prenyltransferase alpha-alpha toroid" evidence="9">
        <location>
            <begin position="8"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG93605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="360" mass="41470" checksum="7D5C2E9921C9D198" modified="2017-02-15" version="1">MCNEIEFVHEKHIKYLNSYTTASNAEELIFNETLKMCGVFYFICSCKILSHKIDKKEEFIEFILRCQNLDGGFGNNIKHDSHIVSTHYAILSLLLLNYSFDNFNIYLENEKNILSNDSSNINNCNDYFKNKKTIREKTCDYIMTLSNDDGSFKGDIWGEVDTRFVYSAVSCLSILNKLNLISTEKISSYLLSNYDLNQNGFSWISGNEPHAASVFCCIATLFLIQKLYLIDEKKLADWLSLRQTSNGGFNGRAEKLTDTCYSWWIFSSLIILKKYKWINKNALKNYILLCQDLDNGGISDNPDCLPDICHTFFGLAALSLIDNLNKLEKKLSLKEMHPVYAIPLNIVKKRNLLYHDIDIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMX5</accession>
    <name>A0A1J1GMX5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Threonylcarbamoyladenosine tRNA methylthiotransferase</fullName>
            <ecNumber evidence="4">2.8.4.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">tRNA-t(6)A37 methylthiotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">PGAL8A_00150700</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>N(6)-L-threonylcarbamoyladenosine(37) in tRNA + (sulfur carrier)-SH + AH2 + 2 S-adenosyl-L-methionine = 2-methylsulfanyl-N(6)-L-threonylcarbamoyladenosine(37) in tRNA + (sulfur carrier)-H + 5'-deoxyadenosine + L-methionine + A + S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:37075"/>
            <dbReference type="Rhea" id="RHEA-COMP:10163"/>
            <dbReference type="Rhea" id="RHEA-COMP:11092"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="ChEBI" id="CHEBI:74418"/>
            <dbReference type="ChEBI" id="CHEBI:74420"/>
            <dbReference type="EC" id="2.8.4.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the methylthiotransferase family. CDKAL1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.4.5" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526620.1">
        <property type="nucleotide sequence ID" value="XM_028675050.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMX5"/>
    <dbReference type="GeneID" id="39730031"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00150700"/>
    <dbReference type="OMA" id="PYILKHV"/>
    <dbReference type="OrthoDB" id="1730074at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035598">
        <property type="term" value="F:tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.30.20:FF:000002">
        <property type="entry name" value="threonylcarbamoyladenosine tRNA methylthiotransferase isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12160">
        <property type="entry name" value="Methylthiotransferase, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="entry name" value="tm_1862 like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005839">
        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013848">
        <property type="entry name" value="Methylthiotransferase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038135">
        <property type="entry name" value="Methylthiotransferase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006466">
        <property type="entry name" value="MiaB-like_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01578">
        <property type="entry name" value="MiaB-like-B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00089">
        <property type="entry name" value="MiaB/RimO family radical SAM methylthiotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11918">
        <property type="entry name" value="RADICAL SAM PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11918:SF45">
        <property type="entry name" value="THREONYLCARBAMOYLADENOSINE TRNA METHYLTHIOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00919">
        <property type="entry name" value="UPF0004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01082">
        <property type="entry name" value="B12-binding_domain_containing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51449">
        <property type="entry name" value="MTTASE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="MTTase N-terminal" evidence="17">
        <location>
            <begin position="193"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="18">
        <location>
            <begin position="418"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="domain" description="TRAM" evidence="16">
        <location>
            <begin position="655"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="148"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00051661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="CRG93798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="721" mass="83563" checksum="A2C6C70A5D356165" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN10</accession>
    <name>A0A1J1GN10_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Nodulation protein E</fullName>
            <ecNumber evidence="3">2.3.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Host-specificity of nodulation protein B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="primary">FabB/FabF</name>
        <name evidence="22" type="ORF">PGAL8A_00154800</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Proposed to synthesize NOD factor fatty acyl chain. Involved in the synthesis of a highly unsaturated fatty acid moiety, which forms part of a lipo-oligosaccharide that is responsible for host specificity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 19">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.41" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN10"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00154800"/>
    <dbReference type="OMA" id="QIGHCLG"/>
    <dbReference type="OrthoDB" id="5334845at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000059">
        <property type="entry name" value="Beta-ketoacyl-acyl-carrier-protein synthase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017568">
        <property type="entry name" value="3-oxoacyl-ACP_synth-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03150">
        <property type="entry name" value="fabF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005589">
        <property type="entry name" value="PRK07314.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712:SF352">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="POLYKETIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="KS3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52004">
        <property type="entry name" value="KS3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="14" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="6" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0536">Nodulation</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="20" id="KW-0732">Signal</keyword>
    <keyword evidence="8 19" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="20">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009618929" description="Nodulation protein E" evidence="20">
        <location>
            <begin position="20"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="Ketosynthase family 3 (KS3)" evidence="21">
        <location>
            <begin position="57"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00037576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00039445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00041756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS52004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="CRG93839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="474" mass="52401" checksum="B16704537187E907" modified="2017-02-15" version="1">MRIYAKYFLFFFLISQVYSKKYGFVKNNLQRTTKNIFRNVRLYDSYNSNQLKNYCETSRVVCTGLGVVTGVGIGIEKFWNNLISGYNSIDKISKFDVTGMACGIGSEINKNDFNPSDFYTNKKDVNRNDDCTHYAVAATRMAIDDANLDLKKIDSDKVGTIIGSGIGGLFFLEKEMKTLYEKGHKRITPYLIPAMIANTPSGFVSIENNLRGISLGMLSACATSGNTIGEAYRYIKYKEYDVMICGGTEASITPISFAGFNALRALCIGYNDNPKKGCRPFDLKRSGFVMGEGSGILILESYEHAIKRNAKIYGEILAYASESDAYHITAPEPSGRGLTNSIKKVLRNGNINISDVKYVNAHGTSTNLNDKIETTVLKNVFKDHAYKLHISSTKSMTGHCIGAAGAIESIACLKAMQTNIIPPTINYENKDPECDLNYTPNKSVHSKEDIDISLNTNLGFGGHNTALLFKKITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN26</accession>
    <name>A0A1J1GN26_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glutamyl-tRNA(Gln) amidotransferase subunit B, putative</fullName>
            <ecNumber evidence="8">6.3.5.-</ecNumber>
            <ecNumber evidence="8">6.3.5.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">GATB</name>
        <name evidence="8" type="ORF">PGAL8A_00157300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-glutamyl-tRNA(Gln) + L-glutamine + ATP + H2O = L-glutaminyl-tRNA(Gln) + L-glutamate + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.-" evidence="8"/>
    <dbReference type="EC" id="6.3.5.7" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526686.1">
        <property type="nucleotide sequence ID" value="XM_028675124.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN26"/>
    <dbReference type="GeneID" id="39730098"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00157300"/>
    <dbReference type="OMA" id="VFFNDPF"/>
    <dbReference type="OrthoDB" id="1722066at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030956">
        <property type="term" value="C:glutamyl-tRNA(Gln) amidotransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070681">
        <property type="term" value="P:glutaminyl-tRNAGln biosynthesis via transamidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017959">
        <property type="entry name" value="Asn/Gln-tRNA_amidoTrfase_suB/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006075">
        <property type="entry name" value="Asn/Gln-tRNA_Trfase_suB/E_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003789">
        <property type="entry name" value="Asn/Gln_tRNA_amidoTrase-B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11659">
        <property type="entry name" value="GLUTAMYL-TRNA GLN AMIDOTRANSFERASE SUBUNIT B MITOCHONDRIAL AND PROKARYOTIC PET112-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11659:SF0">
        <property type="entry name" value="GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT B, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02934">
        <property type="entry name" value="GatB_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89095">
        <property type="entry name" value="GatB/YqeY motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="Aspartyl/Glutamyl-tRNA(Gln) amidotransferase subunit B/E catalytic" evidence="7">
        <location>
            <begin position="166"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="Aspartyl/Glutamyl-tRNA(Gln) amidotransferase subunit B/E catalytic" evidence="7">
        <location>
            <begin position="353"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="699" mass="84064" checksum="B2A042CBA072103A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN48</accession>
    <name>A0A1J1GN48_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00159700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526710.1">
        <property type="nucleotide sequence ID" value="XM_028675150.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730122"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00159700"/>
    <dbReference type="OMA" id="DYNFCSK"/>
    <dbReference type="OrthoDB" id="392868at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="779"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="916"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="309"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="788"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="823"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="844"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="866"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="916"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="941"/>
            <end position="951"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1676" mass="200048" checksum="AD668F6D8FD9828D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN61</accession>
    <name>A0A1J1GN61_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ATP dependent DEAD-box helicase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00152200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526634.1">
        <property type="nucleotide sequence ID" value="XM_028675065.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN61"/>
    <dbReference type="GeneID" id="39730046"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00152200"/>
    <dbReference type="OMA" id="WIFYEHV"/>
    <dbReference type="OrthoDB" id="6692397at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045025">
        <property type="term" value="C:mitochondrial degradosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000965">
        <property type="term" value="P:mitochondrial RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002434">
        <property type="entry name" value="ATP-dependent RNA helicase SUV3, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055206">
        <property type="entry name" value="DEXQc_SUV3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050699">
        <property type="entry name" value="RNA-DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022192">
        <property type="entry name" value="SUV3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131">
        <property type="entry name" value="ATP-DEPENDENT RNA AND DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22527">
        <property type="entry name" value="DEXQc_Suv3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12513">
        <property type="entry name" value="SUV3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 7" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="361"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="117"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="896" mass="105866" checksum="517AB180CA4AA08D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN65</accession>
    <name>A0A1J1GN65_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00147700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526593.1">
        <property type="nucleotide sequence ID" value="XM_028675020.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730001"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00147700"/>
    <dbReference type="OMA" id="YLNIVIK"/>
    <dbReference type="OrthoDB" id="387687at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="731"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2455"/>
            <end position="2504"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1471"/>
            <end position="1498"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1951"/>
            <end position="1978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="736"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2455"/>
            <end position="2497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3090" mass="369293" checksum="589D8F2BE0B2EAC1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN72</accession>
    <name>A0A1J1GN72_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Microtubule-associated protein ytm1 homologue, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00159000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526703.1">
        <property type="nucleotide sequence ID" value="XM_028675142.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN72"/>
    <dbReference type="GeneID" id="39730115"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00159000"/>
    <dbReference type="OMA" id="DHKYVEF"/>
    <dbReference type="OrthoDB" id="10261640at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012972">
        <property type="entry name" value="NLE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19855:SF11">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN WDR12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19855">
        <property type="entry name" value="WD40 REPEAT PROTEIN 12, 37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08154">
        <property type="entry name" value="NLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="NLE" evidence="6">
        <location>
            <begin position="39"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="225"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="376"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="453" mass="52727" checksum="6A7699CA22029483" modified="2017-02-15" version="1">MKNIGEGEEIIDNNIISDNDYNSDTNFSSNENNKCEKQIQICFISNLKDDKYKIENNIYTVPVSFRRIDLSRMIKKLLNIKENISFEFLINKKILRSSIEEFLQLNNILSENVIEVEFTIPITKKESKKIDNISEWISELIIIENTLHCSTFEGNILYYDLTNFNKIYENNVSNMPIFSFNSFKDNKLGSNLYHESIIGLSNGTIKIFLNEEINKGIKTKNQLYLSNHDDMIKSIAINKDASLIISGGTDNKINIYDNNYIIEELKQFKSDNNNKRKKKNVIPPKKSIHKESGIITNLNFFDNIKFLSSGFEKNIKIFDVTNGNIVSSFPYNKSIIRSDIINKNLFIIADENSLIKLFDIRCLNEKSVISLNENKYYSHDKIITSLKGNKNELYFLSSSHDGYINIFDIRLNKLPVYTIENEKKKILSCTWFYRKKNHSIISADEYNINIHNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNC1</accession>
    <name>A0A1J1GNC1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Protein transport protein Sec24A, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">SEC24A</name>
        <name evidence="17" type="ORF">PGAL8A_00167500</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SEC23/SEC24 family. SEC24 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526788.1">
        <property type="nucleotide sequence ID" value="XM_028669992.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNC1"/>
    <dbReference type="GeneID" id="39730201"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00167500"/>
    <dbReference type="OMA" id="AVECSKQ"/>
    <dbReference type="OrthoDB" id="49016at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030127">
        <property type="term" value="C:COPII vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090110">
        <property type="term" value="P:COPII-coated vesicle cargo loading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.380:FF:000012">
        <property type="entry name" value="Protein transport protein Sec24A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1670">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.730">
        <property type="entry name" value="Sec23/Sec24 helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.380">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012990">
        <property type="entry name" value="Beta-sandwich_Sec23_24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007123">
        <property type="entry name" value="Gelsolin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036180">
        <property type="entry name" value="Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006900">
        <property type="entry name" value="Sec23/24_helical_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036175">
        <property type="entry name" value="Sec23/24_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006896">
        <property type="entry name" value="Sec23/24_trunk_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050550">
        <property type="entry name" value="SEC23_SEC24_subfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006895">
        <property type="entry name" value="Znf_Sec23_Sec24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036174">
        <property type="entry name" value="Znf_Sec23_Sec24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13803">
        <property type="entry name" value="SEC24-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13803:SF39">
        <property type="entry name" value="SECRETORY 24AB, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00626">
        <property type="entry name" value="Gelsolin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08033">
        <property type="entry name" value="Sec23_BS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04815">
        <property type="entry name" value="Sec23_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04811">
        <property type="entry name" value="Sec23_trunk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04810">
        <property type="entry name" value="zf-Sec23_Sec24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82754">
        <property type="entry name" value="C-terminal, gelsolin-like domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81811">
        <property type="entry name" value="Helical domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82919">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Zinc finger Sec23/Sec24-type" evidence="13">
        <location>
            <begin position="208"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 trunk" evidence="14">
        <location>
            <begin position="282"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 beta-sandwich" evidence="16">
        <location>
            <begin position="548"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 helical" evidence="15">
        <location>
            <begin position="644"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="domain" description="Gelsolin-like" evidence="12">
        <location>
            <begin position="759"/>
            <end position="813"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF08033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="CRG93967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="905" mass="103554" checksum="422974C78F9839FC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNF8</accession>
    <name>A0A1J1GNF8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">14-3-3 protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00168500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 14-3-3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526799.1">
        <property type="nucleotide sequence ID" value="XM_028670004.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNF8"/>
    <dbReference type="GeneID" id="39730212"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00168500"/>
    <dbReference type="OMA" id="FYWHLLG"/>
    <dbReference type="OrthoDB" id="390416at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.190.20">
        <property type="entry name" value="14-3-3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000308">
        <property type="entry name" value="14-3-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036815">
        <property type="entry name" value="14-3-3_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023410">
        <property type="entry name" value="14-3-3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18860">
        <property type="entry name" value="14-3-3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00244">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000868">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00305">
        <property type="entry name" value="1433ZETA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00101">
        <property type="entry name" value="14_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48445">
        <property type="entry name" value="14-3-3 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="14-3-3" evidence="3">
        <location>
            <begin position="14"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with phosphoserine on interacting protein" evidence="2">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with phosphoserine on interacting protein" evidence="2">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000868-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="273" mass="31650" checksum="06210BBE651C5104" modified="2017-02-15" version="1">MKTNINSKNVLPNKDEFIYCLKMLDNLGFYDEMVASIKSVNVENYNLNYKESLLMGSAFKNALNVKRKEKTIVENIMSNEKSSEKEKVCAELLKSKLNKDIRTIEKNAYIIIKTKCIPRTTDDKVLLFYWHLLGDIFRYCADTFNKEEKKKLHEKSLQSYSFALRIANKMKVFSSSPIMLELLVSLSVLHKDMDKDINFAIEMAAQAFRNAIQNMHLLENDDECSKTIGILGLLRDNINKWCEISGRKNVNALFEIKGENFDKYKNIMNSIHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNR1</accession>
    <name>A0A1J1GNR1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Elongation factor 1-alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00163500</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526747.1">
        <property type="nucleotide sequence ID" value="XM_028675191.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNR1"/>
    <dbReference type="GeneID" id="39730160"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00163500"/>
    <dbReference type="OMA" id="AIRDMGM"/>
    <dbReference type="OrthoDB" id="407705at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01883">
        <property type="entry name" value="EF1_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03693">
        <property type="entry name" value="EF1_alpha_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03705">
        <property type="entry name" value="EF1_alpha_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000003">
        <property type="entry name" value="Elongation factor 1-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000005">
        <property type="entry name" value="Elongation factor 1-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000255">
        <property type="entry name" value="Elongation factor 1-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054696">
        <property type="entry name" value="GTP-eEF1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050100">
        <property type="entry name" value="TRAFAC_GTPase_members"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004539">
        <property type="entry name" value="Transl_elong_EF1A_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00483">
        <property type="entry name" value="EF-1_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008969">
        <property type="entry name" value="PRK12317.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23115">
        <property type="entry name" value="TRANSLATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22594">
        <property type="entry name" value="GTP-eEF1A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8 10" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="7 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="9">
        <location>
            <begin position="5"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG93926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="430" mass="47514" checksum="03782F55FD57EF54" modified="2017-02-15" version="1">MGKEKTHINLVVIGHVDSGKSTTTGHIIYKLGGIDRRTIEKFEKESAEMGKGSFKYAWVLDKLKAERERGITIDIALWKFETPRYYFTVIDAPGHKDFIKNMITGTSQADVALLIVPAEVGGFEGAFSKEGQTKEHALLAFTLGVKQIVVGVNKMDTVKYSEERYEEIKKEVRDYLKKVGYAADKVDFIPWYKGRTLIEALDTMEPPKRPYDKPLRIPLQGVYKIGGIGTVPVGRVETGILKAGMVLNFAPSAVVSECKSVEMHKEVLEEARPGDNIGFNVKNVSVKEIKRGYVASDTKNEPAKGCAKFTAQVIILNHPGEIKNGYTPVLDCHTSHISCKFVNIDSKIDKRSGKVVEENPKAIKSGDSALVSLEPKKPMVVETFTEYPPLGRFAIRDMRQTIAVGIIKSVEKKEPGAVSSNKPAKTGAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNT4</accession>
    <name>A0A1J1GNT4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Exosome complex exonuclease RRP44, putative</fullName>
            <ecNumber evidence="7">3.1.13.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">DIS3</name>
        <name evidence="7" type="ORF">PGAL8A_00165800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RNR ribonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.-" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526771.1">
        <property type="nucleotide sequence ID" value="XM_028675217.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNT4"/>
    <dbReference type="GeneID" id="39730184"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00165800"/>
    <dbReference type="OMA" id="GQVMRNN"/>
    <dbReference type="OrthoDB" id="372421at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071031">
        <property type="term" value="P:nuclear mRNA surveillance of mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09862">
        <property type="entry name" value="PIN_Rrp44-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041505">
        <property type="entry name" value="Dis3_CSD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022966">
        <property type="entry name" value="RNase_II/R_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050180">
        <property type="entry name" value="RNR_Ribonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355:SF35">
        <property type="entry name" value="EXOSOME COMPLEX EXONUCLEASE RRP44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355">
        <property type="entry name" value="RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17849">
        <property type="entry name" value="OB_Dis3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13638">
        <property type="entry name" value="PIN_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01175">
        <property type="entry name" value="RIBONUCLEASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="RNB" evidence="6">
        <location>
            <begin position="521"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="319"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="319"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="360"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="993" mass="117567" checksum="746587C67E1EC7B5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNV6</accession>
    <name>A0A1J1GNV6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00066300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG92959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525781.1">
        <property type="nucleotide sequence ID" value="XM_028674420.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNV6"/>
    <dbReference type="GeneID" id="39729188"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00066300"/>
    <dbReference type="OMA" id="CTWVYDY"/>
    <dbReference type="OrthoDB" id="382491at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG92959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="213" mass="24594" checksum="F3DD94A49475DC9E" modified="2017-02-15" version="1">MASSHESYEDKKETSLDSASNKSENSKKSETSKKSETSKKSETSKKSETSKKSGTSKKSEKSYTPEIEVETFEINEDKDKQYNKFLQCSSNEYSIEQMKNFLKYGITENGIRMMTTDTCSWYYDYYKITKTSTPHLKEFTDNTTVDYYYYTTPFSTQIGSINLVMMHSQVNFGDETCTPSDRFFKMNEATPEMIKEAKIKANQIKNTCCLKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP06</accession>
    <name>A0A1J1GP06_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CLAMP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00173700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526851.1">
        <property type="nucleotide sequence ID" value="XM_028670061.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP06"/>
    <dbReference type="GeneID" id="39730264"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00173700"/>
    <dbReference type="OMA" id="FRNFFFY"/>
    <dbReference type="OrthoDB" id="425082at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032727">
        <property type="entry name" value="CLAMP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28457:SF1">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 119"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28457">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14769">
        <property type="entry name" value="CLAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="365" mass="43988" checksum="1A4E5546957A2EF4" modified="2017-02-15" version="1">MSLKNEDEKNKTEFFVCADINKKKMRKIIISTDKKKQKKLLIKSLHINFNMNKNEKNKKEKLMISIDNFLPKELNNESINIKKNKNEDEDLEYLHSLNTLKKQKMMKIVCDFFYNILIFCINKNLSLVEISTFLSIKKYIFFKFVNSCQNIINLFLEFKKIMLKHSINRIPYYVKVFSYSSLDLLIRYSFKTFFKNFSFYKFIFNPSYKIYFECIDNNSTICEEKDFNKNDDAIPYNLNTPDNINYIKDLIRLNVGSISNLKQKEINKDSPIKEIQKYLYKFNIKNDYIVFEINEFKKDKNLQRIFNDMKNNNDQIHSMNDKKKSELQHEKSINKDKLIKRVDNLYNDLERRIVSNLNQLLNNEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP58</accession>
    <name>A0A1J1GP58_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Cleavage and polyadenylation specificity factor, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PGAL8A_00397700</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS11 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527094.1">
        <property type="nucleotide sequence ID" value="XM_028670331.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP58"/>
    <dbReference type="GeneID" id="39732507"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00397700"/>
    <dbReference type="OMA" id="MFDCGSH"/>
    <dbReference type="OrthoDB" id="10249535at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016180">
        <property type="term" value="P:snRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.15.10:FF:000042">
        <property type="entry name" value="Cleavage and polyadenylation specificity factor,putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10890:FF:000002">
        <property type="entry name" value="Integrator complex subunit 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022712">
        <property type="entry name" value="Beta_Casp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050698">
        <property type="entry name" value="MBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011108">
        <property type="entry name" value="RMMBL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11203">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11203:SF37">
        <property type="entry name" value="INTEGRATOR COMPLEX SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10996">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16661">
        <property type="entry name" value="Lactamase_B_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07521">
        <property type="entry name" value="RMMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01027">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="12">
        <location>
            <begin position="21"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-Casp" evidence="13">
        <location>
            <begin position="316"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="661"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="764"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="154"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="676"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="783"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="801"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="823"/>
            <end position="833"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG94273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="985" mass="114189" checksum="0C9737AF5FBCB7E2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPJ4</accession>
    <name>A0A1J1GPJ4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Rab-GAP TBC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00393200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527049.1">
        <property type="nucleotide sequence ID" value="XM_028670281.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732462"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00393200"/>
    <dbReference type="OrthoDB" id="206700at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1310">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045913">
        <property type="entry name" value="TBC20/Gyp8-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20913:SF7">
        <property type="entry name" value="RE60063P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20913">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 20/GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1363"/>
            <end position="1382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="378"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="378"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1384" mass="167531" checksum="BCE08A8BA41D462B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPN3</accession>
    <name>A0A1J1GPN3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00185900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000024">
        <property type="protein sequence ID" value="CRG94464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527284.1">
        <property type="nucleotide sequence ID" value="XM_028670542.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPN3"/>
    <dbReference type="GeneID" id="39730386"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00185900"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="86" mass="10284" checksum="17CEE0D7DC179DE5" modified="2017-02-15" version="1">MALLYNEGCENFEEDSAICRMSICSIKQNKFEKSYCSLDKKLVKLYRPLNNVSNDISRNIFKYERYGPYRYSRIITCKMLLSRQTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPX2</accession>
    <name>A0A1J1GPX2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-f protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00186600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000025">
        <property type="protein sequence ID" value="CRG94471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527290.1">
        <property type="nucleotide sequence ID" value="XM_028670549.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPX2"/>
    <dbReference type="GeneID" id="39730393"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00186600"/>
    <dbReference type="OrthoDB" id="384111at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="588" mass="70706" checksum="3B45474FB9FFDD2B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQM3</accession>
    <name>A0A1J1GQM3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">SNARE protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00211700</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527535.1">
        <property type="nucleotide sequence ID" value="XM_028670820.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQM3"/>
    <dbReference type="GeneID" id="39730644"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00211700"/>
    <dbReference type="OMA" id="KMAMVMK"/>
    <dbReference type="OrthoDB" id="546861at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048193">
        <property type="term" value="P:Golgi vesicle transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21442">
        <property type="entry name" value="SNARE_NTD_STX6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15841">
        <property type="entry name" value="SNARE_Qc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000124">
        <property type="entry name" value="SNARE protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015260">
        <property type="entry name" value="Syntaxin-6/10/61_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12791">
        <property type="entry name" value="GOLGI SNARE BET1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09177">
        <property type="entry name" value="STX6_10_61_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="11">
        <location>
            <begin position="121"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="45"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="124"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG94720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="212" mass="24848" checksum="186D6BCEAB6FB266" modified="2017-02-15" version="1">MKSEKVDPFYEAKHEVDISVNNLQNLYNKWNNIPDKNSPLAKEKYTLIKEEIKYLNEDLNDLNNSINVVKKNLYKFNISNEEIENRTKSLKIIQKILNGITNNINYNVQKCNDNIMIDYDKVILKRQDNDLEELAESAERLHNAAITINTELKDQQKLLDELENEMDYSNEKMNFVTKKISDYLKTNNPKVLSLILYLSLIAFILLFVLIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR01</accession>
    <name>A0A1J1GR01_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">DEAD box helicase, putative</fullName>
            <ecNumber evidence="13">3.6.4.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00236400</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="13"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527780.1">
        <property type="nucleotide sequence ID" value="XM_028671094.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR01"/>
    <dbReference type="GeneID" id="39730892"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00236400"/>
    <dbReference type="OMA" id="QTHQFRD"/>
    <dbReference type="OrthoDB" id="19182at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034085">
        <property type="term" value="P:establishment of sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006554">
        <property type="entry name" value="Helicase-like_DEXD_c2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010614">
        <property type="entry name" value="RAD3-like_helicase_DEAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472:SF41">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE DDX11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06733">
        <property type="entry name" value="DEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00488">
        <property type="entry name" value="DEXDc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 13" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="685"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="752"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="7"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG94967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1049" mass="126135" checksum="752A69C91078CE2E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRI5</accession>
    <name>A0A1J1GRI5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">eIF4A</name>
        <name evidence="16" type="ORF">PGAL8A_00228100</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DEAD box helicase family. eIF4A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527699.1">
        <property type="nucleotide sequence ID" value="XM_028671003.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRI5"/>
    <dbReference type="GeneID" id="39730808"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00228100"/>
    <dbReference type="OMA" id="FGCQALV"/>
    <dbReference type="OrthoDB" id="10265785at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18046">
        <property type="entry name" value="DEADc_EIF4AII_EIF4AI_DDX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000089">
        <property type="entry name" value="Eukaryotic initiation factor 4A-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000031">
        <property type="entry name" value="Eukaryotic initiation factor 4A-III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044728">
        <property type="entry name" value="EIF4A_DEADc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 12 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 16" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="15">
        <location>
            <begin position="23"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="54"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="235"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="11">
        <location>
            <begin position="23"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="CRG94884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="395" mass="44990" checksum="A3CB9FD9FFE760A8" modified="2017-02-15" version="1">MSAKEEKFNNENDIEGNTEEIVDTFDALGLNEKLLRGIYSYGFEKPSAIQQRGIKPILNGYDTIGQAQSGTGKTATFVISSLQLINYDYVACQALILAPTRELAQQIQKVVLALGDYLKVKCHACVGGTVVREDIDKLKQGVHMVVGTPGRVYDMIDKRHLGVDRLKLFILDEADEMLSRGFKAQIYEVFKKLVPDIQVALFSATMPQEILELTTRFMRDPKTILVKKDELTLEGIRQFYVAVEKEEWKLDTLCDLYETLTITQSIIYCNTRKKVDILTQEMHNRLFTVSCMHGDMDQKDRDLIMREFRSGSTRVLVTTDLLARGIDVQQVSLVINYDLPCSPDTYIHRIGRSGRFGRKGVAINFVTNDDKEKDKLKKIESYYSTQIEEMPLEVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRQ1</accession>
    <name>A0A1J1GRQ1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">U6 snRNA-associated Sm-like protein LSm6, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">LSM6</name>
        <name evidence="15" type="ORF">PGAL8A_00236900</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527785.1">
        <property type="nucleotide sequence ID" value="XM_028671099.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRQ1"/>
    <dbReference type="GeneID" id="39730897"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00236900"/>
    <dbReference type="OMA" id="MYISEQK"/>
    <dbReference type="OrthoDB" id="268799at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005732">
        <property type="term" value="C:sno(s)RNA-containing ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01726">
        <property type="entry name" value="LSm6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000044">
        <property type="entry name" value="Probable U6 snRNA-associated Sm-like protein LSm6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016487">
        <property type="entry name" value="Lsm6/sSmF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11021">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN F SNRNP-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11021:SF1">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006609">
        <property type="entry name" value="snRNP_SmF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 13" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="10 13" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="11 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12 13" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="9 13" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="8 13" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Sm" evidence="14">
        <location>
            <begin position="5"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR006609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG94972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="77" mass="8906" checksum="45A925E9888A7742" modified="2017-02-15" version="1">MTSNSPKDFVENLKGHTVIVRLNNGTDYKGILACLDERMNVALEQTEEYFEGELIEKYNDAFIRGNNVFYIRAIEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS58</accession>
    <name>A0A1J1GS58_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">Tubulin beta chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">PGAL8A_00384800</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 14">Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="13">Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells. Interacts with DCX/apicortin; the interaction stabilizes microtubule assembly.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the tubulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526965.1">
        <property type="nucleotide sequence ID" value="XM_028670187.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS58"/>
    <dbReference type="GeneID" id="39732378"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00384800"/>
    <dbReference type="OMA" id="FLTCCAI"/>
    <dbReference type="OrthoDB" id="1662883at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02187">
        <property type="entry name" value="beta_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.600:FF:000006">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.20:FF:000002">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000003">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013838">
        <property type="entry name" value="Beta-tubulin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002453">
        <property type="entry name" value="Beta_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01163">
        <property type="entry name" value="BETATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00228">
        <property type="entry name" value="TUBULIN_B_AUTOREG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10 14" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 14" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="16">
        <location>
            <begin position="47"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="17">
        <location>
            <begin position="246"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="426"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="429"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00064948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="CRG94144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="445" mass="49804" checksum="FEA8836137B3E5C4" modified="2017-02-15" version="1">MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGTYRGDSDLQLERVDVFYNEATGGRYVPRAILMDLEPGTMDSVRAGPFGQLFRPDNFVFGQTGAGNNWAKGHYTEGAELIDAVLDVVRKEAEGCDCLQGFQITHSLGGGTGSGMGTLLISKIREEYPDRIMETFSVFPSPKVSDTVVEPYNATLSVHQLVENADEVQVIDNEALYDICFRTLKLTTPTYGDLNHLVSAAMSGVTCSLRFPGQLNSDLRKLAVNLIPFPRLHFFMIGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMCASDPRHGRYLTACAMFRGRMSTKEVDEQMLNVQNKNSSYFVEWIPHNTKSSVCDIPPKGLKMAVTFVGNSTAIQEMFKRVSDQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEFEEEEGDVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSE7</accession>
    <name>A0A1J1GSE7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00263400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528041.1">
        <property type="nucleotide sequence ID" value="XM_028671383.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSE7"/>
    <dbReference type="GeneID" id="39731163"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00263400"/>
    <dbReference type="OMA" id="HIFCDEQ"/>
    <dbReference type="OrthoDB" id="377494at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="516" mass="63909" checksum="7492EA973ED6E41A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSR3</accession>
    <name>A0A1J1GSR3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">50S ribosomal protein L9, apicoplast, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00009300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528137.1">
        <property type="nucleotide sequence ID" value="XM_028671490.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSR3"/>
    <dbReference type="GeneID" id="39728615"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00009300"/>
    <dbReference type="OMA" id="KMIHITV"/>
    <dbReference type="OrthoDB" id="370989at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.10">
        <property type="entry name" value="Ribosomal protein L9, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009027">
        <property type="entry name" value="Ribosomal_bL9/RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020070">
        <property type="entry name" value="Ribosomal_bL9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036935">
        <property type="entry name" value="Ribosomal_bL9_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01281">
        <property type="entry name" value="Ribosomal_L9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55658">
        <property type="entry name" value="L9 N-domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal protein L9" evidence="5">
        <location>
            <begin position="58"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="195" mass="23065" checksum="F9F52DAA721CB99A" modified="2017-02-15" version="1">MHTSFFFYIFFYSLFVYLLLKGYLINNVKKTNCLLYATKKNKKKAKLVHITVSSDNEIGRKGEIKKVKLSHAFNYIIPQRLGYRSTPDELAEKEIKENTLGYIDEIKTSFIRNYKKKLNNTIILFYFNKDEKFVVTQDNVLDYLLARGLIRENDDVYEKIKNKKIKITDFGSYTIKYSFINNINIDVAIHIIKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTD8</accession>
    <name>A0A1J1GTD8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00299200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528588.1">
        <property type="nucleotide sequence ID" value="XM_028671991.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTD8"/>
    <dbReference type="GeneID" id="39731525"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00299200"/>
    <dbReference type="OrthoDB" id="368366at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="63" mass="7510" checksum="8318D64F56A8ADFA" modified="2017-02-15" version="1">MKGEYSSKPPTYRWDMNDALNKLKGNIMDLIFFVGFVISILGSFYFFYWLKSREVRTICNKDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTE8</accession>
    <name>A0A1J1GTE8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">60S ribosomal protein L21, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPL21</name>
        <name evidence="4" type="ORF">PGAL8A_00297400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528570.1">
        <property type="nucleotide sequence ID" value="XM_028671970.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTE8"/>
    <dbReference type="GeneID" id="39731507"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00297400"/>
    <dbReference type="OMA" id="INYGDYV"/>
    <dbReference type="OrthoDB" id="1539250at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.70:FF:000001">
        <property type="entry name" value="60S ribosomal protein L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="6.10.250.3260:FF:000001">
        <property type="entry name" value="60S ribosomal protein L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.70">
        <property type="entry name" value="Ribosomal protein L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001147">
        <property type="entry name" value="Ribosomal_eL21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018259">
        <property type="entry name" value="Ribosomal_eL21_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036948">
        <property type="entry name" value="Ribosomal_eL21_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20981">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01157">
        <property type="entry name" value="Ribosomal_L21e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01171">
        <property type="entry name" value="RIBOSOMAL_L21E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="161" mass="18864" checksum="A82D2151653D4675" modified="2017-02-15" version="1">MGGKSRGKRSGTRYKFSKKFRQHGECSANKYLEKLKYGDYVDIICDSTQQKGMPFNYYHGRTGKVFNITKRGVGVLVNKRVKHRIELKKVCVRIEHVRKSKCNQDFLLRKKQNAELIKEAKLKNERICIKRKPEEPKPAAMIKVPKSKIITVEPLPFYEEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTJ6</accession>
    <name>A0A1J1GTJ6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Selenoprotein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">Sel4</name>
        <name evidence="3" type="ORF">PGAL8A_00298700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528583.1">
        <property type="nucleotide sequence ID" value="XM_028671985.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731520"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00298700"/>
    <dbReference type="OMA" id="KGRASXR"/>
    <dbReference type="OrthoDB" id="392920at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0711">Selenium</keyword>
    <keyword evidence="3" id="KW-0712">Selenocysteine</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="non-standard amino acid" description="Selenocysteine" evidence="3">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="135" mass="16486" checksum="E513C0892ED51E57" modified="2017-02-15" version="1">MERLENKISENYMTIFTLKNVVLLFIGIFLFIFIFKSFKNKNKIYEVKHNSEIDKKMKIAREKKLQELEKEMIANKEKMKEEQIKKREEEKEDRMLNSSKQKLGSKDNSSFNHFKDYSSYYRPSIRNRYKKSSUQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTL5</accession>
    <name>A0A1J1GTL5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00306400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528660.1">
        <property type="nucleotide sequence ID" value="XM_028672070.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTL5"/>
    <dbReference type="GeneID" id="39731597"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00306400"/>
    <dbReference type="OrthoDB" id="373574at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="309" mass="36584" checksum="0B6E68F43B9F2810" modified="2017-02-15" version="1">MCNKYDMANAVIKHCDEDHGIVFNKKPSKNENKFSIIYDYSVSSISKNSNISNSLHSLERITNNKSFKIFDNMSHPKCYYKSSLENLKKNKEQKNDNKYSDETKTEEVKKKNKTTEIFNDTYEVIAPEGRGKFIKFIGENYVYVMLENGTYNCYPVELLKLNCSYLKKNKIYNLCYNYKDIALRHTRNVLKLKNNSLDKNEDILNKEKKSSDDFLHFPEEMDYLRYYIIKNDIEDENASENEYLTHTIVKKMKPKDNENDKNYLHDPIIPIKKNVTIKKMNNEYKIEKTSSYIPVDYINFDNENCNTCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTT1</accession>
    <name>A0A1J1GTT1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">U6 snRNA-associated Sm-like protein LSm7, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">LSM7</name>
        <name evidence="10" type="ORF">PGAL8A_00312900</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528724.1">
        <property type="nucleotide sequence ID" value="XM_028672141.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTT1"/>
    <dbReference type="GeneID" id="39731662"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00312900"/>
    <dbReference type="OMA" id="TICVKFQ"/>
    <dbReference type="OrthoDB" id="2146at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990726">
        <property type="term" value="C:Lsm1-7-Pat1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097526">
        <property type="term" value="C:spliceosomal tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005689">
        <property type="term" value="C:U12-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01729">
        <property type="entry name" value="LSm7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017132">
        <property type="entry name" value="Lsm7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044641">
        <property type="entry name" value="Lsm7/SmG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10553">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10553:SF5">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037188">
        <property type="entry name" value="U6_snRNA_Lsm7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="9">
        <location>
            <begin position="14"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG95916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="106" mass="11917" checksum="30C536A098EE9756" modified="2017-02-15" version="1">MSVLPTVPTQKDNKFMMDIKKFLNQKIRVKFDGGREVVGNLIGHDAIFNLVLDKTEEYIRDPNDHFVLTEKTRSIGLIVARGTSVALITPVEGTEEISNPFITSQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTV9</accession>
    <name>A0A1J1GTV9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mitochondrial import inner membrane translocase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">TIM8</name>
        <name evidence="3" type="ORF">PGAL8A_00293400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the small Tim family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528537.1">
        <property type="nucleotide sequence ID" value="XM_028671934.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTV9"/>
    <dbReference type="GeneID" id="39731467"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00293400"/>
    <dbReference type="OrthoDB" id="344165at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.810">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit tim13 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004217">
        <property type="entry name" value="Tim10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035427">
        <property type="entry name" value="Tim10-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02953">
        <property type="entry name" value="zf-Tim10_DDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144122">
        <property type="entry name" value="Tim10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="1" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="1" id="KW-0653">Protein transport</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0811">Translocation</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Tim10-like" evidence="2">
        <location>
            <begin position="31"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU367043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="109" mass="12939" checksum="D38C8C98E8A84043" modified="2017-02-15" version="1">MENEIKEENLDNFLAQLNKLNQIITSFKESTKIASYCFNKCVSYPEKSLSKSNKKCIWNCTQRYLECDYFIKRRSKDKKNLSNFNLLDDMNKLTKLSKLSNDSEYILKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUA1</accession>
    <name>A0A1J1GUA1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Mitogen-activated protein kinase</fullName>
            <ecNumber evidence="7">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">MAPK1</name>
        <name evidence="10" type="ORF">PGAL8A_00303100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="7">Activated by threonine and tyrosine phosphorylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528627.1">
        <property type="nucleotide sequence ID" value="XM_028672034.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUA1"/>
    <dbReference type="GeneID" id="39731564"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00303100"/>
    <dbReference type="OMA" id="WHEKIKT"/>
    <dbReference type="OrthoDB" id="192887at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004707">
        <property type="term" value="F:MAP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07852">
        <property type="entry name" value="STKc_MAPK15-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000238">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:001058">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003527">
        <property type="entry name" value="MAP_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01351">
        <property type="entry name" value="MAPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="23"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="375"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="382"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG95819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="614" mass="71857" checksum="273FEC74419A4321" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUJ5</accession>
    <name>A0A1J1GUJ5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dynein regulatory complex protein 10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00336500</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Flagellum axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DRC10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528954.1">
        <property type="nucleotide sequence ID" value="XM_028672397.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUJ5"/>
    <dbReference type="GeneID" id="39731895"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00336500"/>
    <dbReference type="OMA" id="KWKKHMR"/>
    <dbReference type="OrthoDB" id="371510at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042815">
        <property type="entry name" value="DRC10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31598:SF1">
        <property type="entry name" value="DYNEIN REGULATORY COMPLEX PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31598">
        <property type="entry name" value="IQ DOMAIN-CONTAINING PROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="153"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="279"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG96149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="377" mass="45887" checksum="ECF7208DE157DBA2" modified="2017-02-15" version="1">MIETKFIDTDAKRLYNVIEIFEKKMISLSLINEEVLEKLNDKEMKTMPEEFLIYFKDIIKLNKLYEHIRIERIEEETEKTNDNENFPFYIEHQELVEKIKKYCFVLCKILKENNNLFEILNLSNDKDNHDFFKFLHIINDLKDIFFIRFQTTAEEKLKRIHSLEELKEEEKKIQDEEKKLNEELERIRKESQNEIKELEDILLNKEKELDYLKKSSEENIKKLLSMIPTNDSSDNLENINILFEKTKNIYENQIKTYQDQEVGLVKKNKLLELDIKNYIDSIDEEIKIMDNEIEKLSNELKKNRIIENDLDTILMRKKREDEENKFLKELTEKRNRIIQREENINNEAAIIIQSYIRAIKQRNLFSDYQKKKRKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUS2</accession>
    <name>A0A1J1GUS2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">NAD(P)H-hydrate epimerase</fullName>
            <ecNumber evidence="3 10">5.1.99.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">NAD(P)HX epimerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00219000</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>(6R)-NADHX = (6S)-NADHX</text>
            <dbReference type="Rhea" id="RHEA:32215"/>
            <dbReference type="ChEBI" id="CHEBI:64074"/>
            <dbReference type="ChEBI" id="CHEBI:64075"/>
            <dbReference type="EC" id="5.1.99.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 10">
            <text>(6R)-NADPHX = (6S)-NADPHX</text>
            <dbReference type="Rhea" id="RHEA:32227"/>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
            <dbReference type="ChEBI" id="CHEBI:64077"/>
            <dbReference type="EC" id="5.1.99.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="10">Binds 1 potassium ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the NnrE/AIBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.99.6" evidence="3 10"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527608.1">
        <property type="nucleotide sequence ID" value="XM_028670902.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUS2"/>
    <dbReference type="GeneID" id="39730717"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00219000"/>
    <dbReference type="OMA" id="RHLFHYG"/>
    <dbReference type="OrthoDB" id="10064708at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052856">
        <property type="term" value="F:NAD(P)HX epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10260">
        <property type="entry name" value="YjeF N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01966">
        <property type="entry name" value="NADHX_epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004443">
        <property type="entry name" value="YjeF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036652">
        <property type="entry name" value="YjeF_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032976">
        <property type="entry name" value="YJEFN_prot_NAXE-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00197">
        <property type="entry name" value="yjeF_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13232">
        <property type="entry name" value="NAD(P)H-HYDRATE EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13232:SF10">
        <property type="entry name" value="NAD(P)H-HYDRATE EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03853">
        <property type="entry name" value="YjeF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64153">
        <property type="entry name" value="YjeF N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51385">
        <property type="entry name" value="YJEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7 10" id="KW-0630">Potassium</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YjeF N-terminal" evidence="11">
        <location>
            <begin position="66"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="117"/>
            <end position="121"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="184"/>
            <end position="190"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG94793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="283" mass="32584" checksum="F259901612CB91EA" modified="2017-02-15" version="1">MKRNFLIRTYKFLISRHNIYLLNFINFLKLKSSIYVNKTYAISKKKNRNILKINKMEITYLSQALAQTIDNELMSEEIGYTTEQLMELAGLSISQIIFHEYSLSKFPKILICCGPGNNGGDGLVAARHLKEFGYDVAVNYPKENNKILFKRLLKLLENYEIKILKDITPDELNKYDLIIDSIFGFSFKGEPRKPFDDIIKMINNCKKSIVSVDVPSGYQIDSGDTGNLCINSEMNISLMLPKQGLKNYQKKHYLGGRFLPSSIIKKYNLKVPHFSGYNSFIML</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUT5</accession>
    <name>A0A1J1GUT5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00321600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000048">
        <property type="protein sequence ID" value="CRG96003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528811.1">
        <property type="nucleotide sequence ID" value="XM_028672239.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUT5"/>
    <dbReference type="GeneID" id="39731749"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00321600"/>
    <dbReference type="OrthoDB" id="6362699at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="313"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="358" mass="42270" checksum="28095020AC1B1BD3" modified="2017-02-15" version="1" fragment="single">MALLYNRGCDDFERDSATCHMTICPINKCKFETSYCRANINSIKVYRPSDNVSNDFSKNTFKYKRYGPYKFSRIIILSNNDQDGIVFLYEFNPYMDDFPIKTYLCRLRNINQTLSLCESIDPYYLDKSLSFNSFDIINEKNDLANLKHIKNPRHQIIISTYKDLYYKEHSCHLIKSKFFTHLRCVNYLCEKDNGEYNLCTDANYSGKLVAFDYYSYERNLKELIYLPESCLKKDYNFACTPYYCQRKAINQFSLCDYKEISAIKNIATNSTSLDVIATSSKSLNVISRNSKSLDVISTKQHNVYHENNLSSPALFAMTFMPFLILFVFFWCYIYKIMKKKRSKLFIKYLSILMLILRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV55</accession>
    <name>A0A1J1GV55_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">M1-family alanyl aminopeptidase, putative</fullName>
            <ecNumber evidence="3">3.4.11.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00231900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.2" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527736.1">
        <property type="nucleotide sequence ID" value="XM_028671044.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV55"/>
    <dbReference type="GeneID" id="39730846"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00231900"/>
    <dbReference type="OMA" id="YINTFCE"/>
    <dbReference type="OrthoDB" id="79562at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016285">
        <property type="term" value="F:alanyl aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="387"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="426"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="624"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="657"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="936"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="989"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 membrane alanine aminopeptidase" evidence="2">
        <location>
            <begin position="456"/>
            <end position="657"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1065" mass="130135" checksum="6C6720D6F9225157" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV71</accession>
    <name>A0A1J1GV71_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ER membrane protein complex subunit 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00367400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529254.1">
        <property type="nucleotide sequence ID" value="XM_028672730.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV71"/>
    <dbReference type="GeneID" id="39732204"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00367400"/>
    <dbReference type="OMA" id="PHCAING"/>
    <dbReference type="OrthoDB" id="194468at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072546">
        <property type="term" value="C:EMC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08060">
        <property type="entry name" value="MPN_UPF0172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005366">
        <property type="entry name" value="EMC8/9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12941">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12941:SF10">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 8_9 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03665">
        <property type="entry name" value="UPF0172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="197" mass="23064" checksum="D27D818235B38459" modified="2017-02-15" version="1">MKDIEITIDNCAYAKIFMHALKNSYDDVCGILIGKYSEDEKKGKKCSITNSIPLFHTHILAPFLNLSFTMVENYYKNKEEKIIGYYHINADESKNNDIKNIKICELISDKLIKNYKNALICLVQISKINNNDDNCLNIYMKGDTFEWKNVDINISNENKEFLKKYISNNSYMDICDFDDHLNCINYDFMNPDLFKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV85</accession>
    <name>A0A1J1GV85_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcription factor with AP2 domain(S), putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ApiAP2</name>
        <name evidence="1" type="ORF">PGAL8A_00342200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529009.1">
        <property type="nucleotide sequence ID" value="XM_028672459.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV85"/>
    <dbReference type="GeneID" id="39731952"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00342200"/>
    <dbReference type="OrthoDB" id="361126at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2050">
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="232" mass="27550" checksum="BA69E429237B8439" modified="2017-02-15" version="1">MNINNTIFLLKKKDKINISIFCSAKLLHTSKICKNRKSLKYLTSIKNNSSVNIQKTKEEYVDKNLSTDIKKKSDFIQYVFKWGIGNKFRSDPENRFHPVHLNRSKEVTIRKNYFDSVNDNIKYEELNEQWEVFWFENNKLNAKPFPIKKYGIEAAKKEAIKFFESLKINNRVNAKPKFESGVEGVHYDVVTNCWISFYRLNNFPICRSFSAEYHGFETAKKMAIERVKRYQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVB7</accession>
    <name>A0A1J1GVB7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00339200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528979.1">
        <property type="nucleotide sequence ID" value="XM_028672426.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVB7"/>
    <dbReference type="GeneID" id="39731922"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00339200"/>
    <dbReference type="OMA" id="ICAPMSE"/>
    <dbReference type="OrthoDB" id="371399at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="776" mass="93415" checksum="6ECFEAA3831E072C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVD6</accession>
    <name>A0A1J1GVD6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glycerol-3-phosphate dehydrogenase [NAD(+)]</fullName>
            <ecNumber evidence="9">1.1.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">G3PDH</name>
        <name evidence="12" type="ORF">PGAL8A_00341600</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4 9">
            <text>sn-glycerol 3-phosphate + NAD(+) = dihydroxyacetone phosphate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11092"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.8" evidence="9"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529003.1">
        <property type="nucleotide sequence ID" value="XM_028672452.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVD6"/>
    <dbReference type="GeneID" id="39731946"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00341600"/>
    <dbReference type="OMA" id="NNRHENI"/>
    <dbReference type="OrthoDB" id="10263760at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141152">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046168">
        <property type="term" value="P:glycerol-3-phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000004">
        <property type="entry name" value="Glycerol-3-phosphate dehydrogenase [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000365">
        <property type="entry name" value="Glycerol-3-phosphate dehydrogenase [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006168">
        <property type="entry name" value="G3P_DH_NAD-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006109">
        <property type="entry name" value="G3P_DH_NAD-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017751">
        <property type="entry name" value="G3P_DH_NAD-dep_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011128">
        <property type="entry name" value="G3P_DH_NAD-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03376">
        <property type="entry name" value="glycerol3P_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11728">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11728:SF8">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE [NAD(+)]-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07479">
        <property type="entry name" value="NAD_Gly3P_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01210">
        <property type="entry name" value="NAD_Gly3P_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000114">
        <property type="entry name" value="Glycerol-3-P_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00077">
        <property type="entry name" value="GPDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 8" id="KW-0520">NAD</keyword>
    <keyword evidence="2 8 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal" evidence="10">
        <location>
            <begin position="44"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal" evidence="11">
        <location>
            <begin position="234"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="245"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="49"/>
            <end position="54"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="309"/>
            <end position="310"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="338"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="340"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG96198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="396" mass="45137" checksum="1C9661499AB2CF37" modified="2017-02-15" version="1">MLKKYFLYNIIFLSHLIKCFSNNQVNFLNQNSLIANVKNNKPLKVSIIGSGNWGTVISKIIGANAKKLKNFYPIVKMYVKEEIIDNEKLSDIINKKKENVKYMKGMKIPDNIVAVSDLNEATEEADLLVFVLPHQYLNNVLNEIKKNNNLKKDAKAISLMKGIKIDNWKPELLSNIIQKELNIECSALSGSNIAKEISEEYFSESTIGFENRETVEIWQNLFDTNYFKINCIQDKAGVEICGALKNVVAMGVGFCDGLTNSFNTKSAIIRIGLEEIKKFAKIFFPNVLDETFLDSCGLADLITTCLGGRNLKCAKEFAIRKGKTTWEKIEEELLNGQKLQGIHTVKEVYSVLEYHNLKKDFPLFCTIYEISFENRDPSDVIQVFATKKLRHIKFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVJ5</accession>
    <name>A0A1J1GVJ5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DnaJ protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00370700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529287.1">
        <property type="nucleotide sequence ID" value="XM_028672768.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVJ5"/>
    <dbReference type="GeneID" id="39732237"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00370700"/>
    <dbReference type="OMA" id="WFWRYTV"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044632">
        <property type="entry name" value="DNAJC25-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44176">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44176:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="7">
        <location>
            <begin position="36"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="321" mass="39643" checksum="34BCE6308DE4C70F" modified="2017-02-15" version="1">MKIFYFAIIIFYFTLISNVNCLFKKVISHFYCHNENCYEILGISQKASPEEIKYSYYKKLNNIKKSHDSKKKKKVVKAFNMLINKRTRNYYDYYLNNPNSIVNLIYFSFYCFYKLFKVILILLIVCLFICLFQYIHNRYEVKRIIQKCSKNKLFKREVQNRIAEEYPDFHNYDLKKKRKIEQKVEEDVVQEIVMVNNQKTRRIGISDLIIVKIIFLPRYIWNYVKWNLKWLIKYNILNEEYDENDKIYITRKYMNISLEKWNSLNEEEKKNYLKKELWIRQNLEDFLQEQREKERINKISSSKYKKQIRMKKKGVSFNYND</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVJ6</accession>
    <name>A0A1J1GVJ6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CPW-WPC family protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00414900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529374.1">
        <property type="nucleotide sequence ID" value="XM_028672863.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVJ6"/>
    <dbReference type="GeneID" id="39732680"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00414900"/>
    <dbReference type="OMA" id="FWPCKKC"/>
    <dbReference type="OrthoDB" id="361166at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006387">
        <property type="entry name" value="CPW_WPC_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01492">
        <property type="entry name" value="CPW_WPC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09717">
        <property type="entry name" value="CPW_WPC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01099">
        <property type="entry name" value="CPW_WPC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012294770" evidence="1">
        <location>
            <begin position="21"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="CPW-WPC" evidence="2">
        <location>
            <begin position="94"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="CPW-WPC" evidence="2">
        <location>
            <begin position="161"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="250" mass="29026" checksum="3FA3C259589FDC8D" modified="2017-02-15" version="1">MTKLFLYLFFLIFYFKINMCVREKKDEIFSNRELENIGGSAGDIITSSSNAPSKEQNETPDSNIAANLIKGLKNIPPPIIQLNQDNLIDPVIICEKDYNLPCPNDYNYIGSVHETEDEICAPSSLYNGPCKGEELNIKNMSEKIKETWSNKCQAFWPCKKCVRNFTYFCPEKWNKVKDTIRSCKPSELYNGPCNFQMNFSGYNIRMLEEWSLKCKAWWKCDHLNLFDECPDGDFPITPAATKWRIKKNYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVK9</accession>
    <name>A0A1J1GVK9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Structural maintenance of chromosomes protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00350400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SMC family. SMC5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529091.1">
        <property type="nucleotide sequence ID" value="XM_028672550.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVK9"/>
    <dbReference type="GeneID" id="39732034"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00350400"/>
    <dbReference type="OMA" id="RFWTSQP"/>
    <dbReference type="OrthoDB" id="10254973at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030915">
        <property type="term" value="C:Smc5-Smc6 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45916">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45916:SF1">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rad50/SbcC-type AAA" evidence="6">
        <location>
            <begin position="90"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="252"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="368"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="738"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="874"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="972"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1184" mass="140790" checksum="6FDEBB7D6F1C6F42" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVL0</accession>
    <name>A0A1J1GVL0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S acidic ribosomal protein P2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00008900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein P1/P2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528133.1">
        <property type="nucleotide sequence ID" value="XM_028671485.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVL0"/>
    <dbReference type="GeneID" id="39728611"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00008900"/>
    <dbReference type="OMA" id="MKVIASY"/>
    <dbReference type="OrthoDB" id="1227494at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002182">
        <property type="term" value="P:cytoplasmic translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05833">
        <property type="entry name" value="Ribosomal_P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1410:FF:000002">
        <property type="entry name" value="60S acidic ribosomal protein P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01478">
        <property type="entry name" value="Ribosomal_L12_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038716">
        <property type="entry name" value="P1/P2_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027534">
        <property type="entry name" value="Ribosomal_P1/P2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044076">
        <property type="entry name" value="Ribosomal_P2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21141">
        <property type="entry name" value="60S ACIDIC RIBOSOMAL PROTEIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21141:SF5">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00428">
        <property type="entry name" value="Ribosomal_60s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="78"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="83"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="95"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="111" mass="11964" checksum="4D6881B87D141984" modified="2017-02-15" version="1">MAMKYVAAYLMCVLGGNENPGTNEVKNVLEAVNAGIDDEVLSNFLNSLKGKNHCDLINEGLKKLQNIGGGAVAAAAASSTENVEVKKEEKKEEKKEEEEEEEDDLGFSLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVV1</accession>
    <name>A0A1J1GVV1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00018700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528229.1">
        <property type="nucleotide sequence ID" value="XM_028671592.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVV1"/>
    <dbReference type="GeneID" id="39728709"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00018700"/>
    <dbReference type="OMA" id="HIEIKEF"/>
    <dbReference type="OrthoDB" id="364825at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="569"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="571"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="613" mass="73997" checksum="5A2289DF978670AC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVZ8</accession>
    <name>A0A1J1GVZ8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Arginase</fullName>
            <ecNumber evidence="2 9">3.5.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00419100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-arginine + H2O = urea + L-ornithine</text>
            <dbReference type="Rhea" id="RHEA:20569"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16199"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="EC" id="3.5.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="9">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nitrogen metabolism; urea cycle; L-ornithine and urea from L-arginine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the arginase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.3.1" evidence="2 9"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529415.1">
        <property type="nucleotide sequence ID" value="XM_028672909.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVZ8"/>
    <dbReference type="GeneID" id="39732723"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00419100"/>
    <dbReference type="OMA" id="YKEFRYA"/>
    <dbReference type="OrthoDB" id="288726at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004053">
        <property type="term" value="F:arginase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006525">
        <property type="term" value="P:arginine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.10">
        <property type="entry name" value="Ureohydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014033">
        <property type="entry name" value="Arginase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01229">
        <property type="entry name" value="rocF_arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43782">
        <property type="entry name" value="ARGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43782:SF3">
        <property type="entry name" value="ARGINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00116">
        <property type="entry name" value="ARGINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0056">Arginine metabolism</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9" id="KW-0464">Manganese</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG96611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="377" mass="42795" checksum="2C6A746097224C9C" modified="2017-02-15" version="1">MLESIENYIKTFKEKKNLYVEKNVSIIGSPLGAGQPLGGVQLACDDLRKLGLHNVINFLGWKYEDLGNIEEHNEINKKKGEEENVEIDNRGKKVYSSDKPLNGCNNIICEPITKKYLENDYYSNIKNIELIGKFSERLFHVMSNELKKKNFVLNIGGDHSVAFASILSSLQIYKDLRVIWIDAHGDINTPETSPSGNYHGMPLAHSLGLFKKKVPYFEWSENLIYLKPENLAIIGIRDIDTYEKIILKKYNINYYTIFDVEQNGIYNTILNALKRIDPNEKCPIHISLDIDSVDNIFAPGTGTIAKGGLTYREINLLMKILSDTKRVVSMDLVEYNPSLDEKEKKFHGDSLPISENATKTGKLCLELIARVLGYDIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW82</accession>
    <name>A0A1J1GW82_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Monocarboxylate transporter, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00439200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529614.1">
        <property type="nucleotide sequence ID" value="XM_028673130.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW82"/>
    <dbReference type="GeneID" id="39732925"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00439200"/>
    <dbReference type="OMA" id="MKAIMIS"/>
    <dbReference type="OrthoDB" id="410267at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17353">
        <property type="entry name" value="MFS_OFA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052983">
        <property type="entry name" value="MFS_Riboflavin_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43385">
        <property type="entry name" value="RIBOFLAVIN TRANSPORTER RIBJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43385:SF1">
        <property type="entry name" value="RIBOFLAVIN TRANSPORTER RIBJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="105"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="140"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="355"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="417"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="446"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="490"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="513"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="532" mass="60365" checksum="87C41A5B73FFDD73" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWC3</accession>
    <name>A0A1J1GWC3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PPPDE peptidase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00432000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DeSI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529543.1">
        <property type="nucleotide sequence ID" value="XM_028673051.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWC3"/>
    <dbReference type="GeneID" id="39732852"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00432000"/>
    <dbReference type="OMA" id="SINTMDI"/>
    <dbReference type="OrthoDB" id="412286at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0101005">
        <property type="term" value="F:deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1720.30">
        <property type="entry name" value="PPPDE domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008580">
        <property type="entry name" value="PPPDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042266">
        <property type="entry name" value="PPPDE_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12378">
        <property type="entry name" value="DESUMOYLATING ISOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12378:SF80">
        <property type="entry name" value="IP06716P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05903">
        <property type="entry name" value="Peptidase_C97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01179">
        <property type="entry name" value="DUF862"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51858">
        <property type="entry name" value="PPPDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPPDE" evidence="4">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="246" mass="28800" checksum="7516D4EB32C99367" modified="2017-02-15" version="1">MNIFLHTYTLNVPFFLKNVRHTGIEVFGKEYTFSMAGIITCKPKKSTIGKYSKSYELSYMQLTYSQFSEILNALGKIYRPNTYNFIYKNCNHFCDDLFELLSGKRLFHRFMFYSRLGKLVGNFKNVALCGYINTVEFSSNDKTLYIYALNLSKSILKRNKKLKNSEGILYIKDKNANYYERCNSTFHIIPYSNYENDTCNKQIAYYKDYIINETIKCLNNEVGKYIHQPQLKSIYSFSTTGTSSLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWC4</accession>
    <name>A0A1J1GWC4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ATP-dependent protease ATPase subunit ClpY, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ClpY</name>
        <name evidence="8" type="ORF">PGAL8A_00420100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ClpX chaperone family. HslU subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529425.1">
        <property type="nucleotide sequence ID" value="XM_028672920.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWC4"/>
    <dbReference type="GeneID" id="39732733"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00420100"/>
    <dbReference type="OMA" id="YNYVNQT"/>
    <dbReference type="OrthoDB" id="1721884at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009376">
        <property type="term" value="C:HslUV protease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050052">
        <property type="entry name" value="ATP-dep_Clp_protease_ClpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004491">
        <property type="entry name" value="HslU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00390">
        <property type="entry name" value="hslU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003544">
        <property type="entry name" value="PRK05201.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102:SF3">
        <property type="entry name" value="ATP-DEPENDENT PROTEASE ATPASE SUBUNIT HSLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="412"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="domain" description="Clp ATPase C-terminal" evidence="7">
        <location>
            <begin position="696"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="563"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="804" mass="93282" checksum="B8DF9C80227C16BD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWG3</accession>
    <name>A0A1J1GWG3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Deoxyhypusine synthase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00284200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the deoxyhypusine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528453.1">
        <property type="nucleotide sequence ID" value="XM_028671840.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWG3"/>
    <dbReference type="GeneID" id="39731375"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00284200"/>
    <dbReference type="OMA" id="HSIINAN"/>
    <dbReference type="OrthoDB" id="294378at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034038">
        <property type="term" value="F:deoxyhypusine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.910.10">
        <property type="entry name" value="Deoxyhypusine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002773">
        <property type="entry name" value="Deoxyhypusine_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036982">
        <property type="entry name" value="Deoxyhypusine_synthase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00321">
        <property type="entry name" value="dhys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11703">
        <property type="entry name" value="DEOXYHYPUSINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11703:SF0">
        <property type="entry name" value="DEOXYHYPUSINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01916">
        <property type="entry name" value="DS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="228"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="429" mass="49155" checksum="B028CCD46D450CDF" modified="2017-02-15" version="1">MYKTTFKEINKIKSESDNDESTDEKNSISDAMSSVFVKSTKIPDNIDVVKGINFDKEINIHEFINHYKYMGFQATNLGIGIDEINKMIHLKYIDNNGKNEINDNNGNKKKCMIWLSFTSNMISSGLREIFVYLAKNRFVDVIVTTAGGIEEDIIKCFSNTYLGDFSLNGKKLRKKGWNRIGNLIVPNENYCKFEDWLQPLLNKMLDEQNEKNEEIFLKKLEKRKKREEKKENEKKSNCDQNESDSDEESDLFYLSPSEFINRLGKEINDESSLIYWCYKNNIPVFCPGLTDGSLGDNLFFHNYGKKIKNNLILDIIKDIKKINSLALNCRKSGIIILGGGLPKHHVCNANLMRNGADYAVYVNTANEYDGSDSGANTTEALSWGKIKSGNKNNHVKVFGDATILFPLMVLNTFYLYSQNKKKRNTEIKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWG8</accession>
    <name>A0A1J1GWG8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NECAP-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00418750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529411.1">
        <property type="nucleotide sequence ID" value="XM_028672905.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWG8"/>
    <dbReference type="GeneID" id="39732719"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00418750"/>
    <dbReference type="OMA" id="IKINIAX"/>
    <dbReference type="OrthoDB" id="10265489at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030125">
        <property type="term" value="C:clathrin vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012466">
        <property type="entry name" value="NECAP_PHear"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12847">
        <property type="entry name" value="ATP-BINDING CASSETTE ABC TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12847:SF9">
        <property type="entry name" value="NECAP-LIKE PROTEIN CG9132"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07933">
        <property type="entry name" value="DUF1681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NECAP PHear" evidence="1">
        <location>
            <begin position="7"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="176" mass="21071" checksum="BFE4D45E2648BBF7" modified="2017-02-15" version="1">MCELFLLFKHQKVDIFKIPPRPFEGHRAELWTEKIWEGFVVLYIKNDQIILKLVDENEVLFAQCVIPHNYETVVEKAIDSSRYFSIRVENTNDKNEIMYSFIGIFFEERTVAFNFLCTINDFYRFKIFNSKFNSVIEKKKLHKMNEGEKITIKIKGLKVKERKETNDKNFDLESPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWK1</accession>
    <name>A0A1J1GWK1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00288200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528493.1">
        <property type="nucleotide sequence ID" value="XM_028671885.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731415"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00288200"/>
    <dbReference type="OrthoDB" id="381420at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1670"/>
            <end position="1704"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3096" mass="364019" checksum="EFE6B81FA14FF00E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWP0</accession>
    <name>A0A1J1GWP0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00425900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529483.1">
        <property type="nucleotide sequence ID" value="XM_028672985.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWP0"/>
    <dbReference type="GeneID" id="39732791"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00425900"/>
    <dbReference type="OrthoDB" id="239865at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="944" mass="114147" checksum="3F3D80022C727671" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWP7</accession>
    <name>A0A1J1GWP7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Arginine--tRNA ligase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00426700</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529491.1">
        <property type="nucleotide sequence ID" value="XM_028672994.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWP7"/>
    <dbReference type="GeneID" id="39732799"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00426700"/>
    <dbReference type="OrthoDB" id="68056at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004814">
        <property type="term" value="F:arginine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006420">
        <property type="term" value="P:arginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001278">
        <property type="entry name" value="Arg-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035684">
        <property type="entry name" value="ArgRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008909">
        <property type="entry name" value="DALR_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956:SF5">
        <property type="entry name" value="ARGININE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956">
        <property type="entry name" value="ARGINYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05746">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00750">
        <property type="entry name" value="tRNA-synt_1d"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01038">
        <property type="entry name" value="TRNASYNTHARG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 7 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012475672" evidence="8">
        <location>
            <begin position="21"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="domain" description="Arginyl-tRNA synthetase catalytic core" evidence="9">
        <location>
            <begin position="182"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="Arginyl-tRNA synthetase catalytic core" evidence="9">
        <location>
            <begin position="348"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="Arginyl-tRNA synthetase catalytic core" evidence="9">
        <location>
            <begin position="511"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="domain" description="DALR anticodon binding" evidence="10">
        <location>
            <begin position="692"/>
            <end position="750"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG96687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="869" mass="104073" checksum="81D2ED52AF84B0F2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWS7</accession>
    <name>A0A1J1GWS7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00447300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529695.1">
        <property type="nucleotide sequence ID" value="XM_028673220.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWS7"/>
    <dbReference type="GeneID" id="39733006"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00447300"/>
    <dbReference type="OMA" id="HAFDYFI"/>
    <dbReference type="OrthoDB" id="420623at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="145" mass="17382" checksum="2F392204C037A9E2" modified="2017-02-15" version="1">MHYNLIKSKINTNYVIDPYVSMLYLKRAYKYLQLLKKNNGNIIILGNKFNEIKLENYFKNIEHKEKCDLNTLTNVTKSYDLLICTDLPLYYSHIKNIFLPKMLIADGYSFVKNKNYLHIFDYFIPLTNQKLDKHLHYVLSKKYLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWU0</accession>
    <name>A0A1J1GWU0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HD superfamily phosphohydrolase protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00460700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529830.1">
        <property type="nucleotide sequence ID" value="XM_028673371.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWU0"/>
    <dbReference type="GeneID" id="39733140"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00460700"/>
    <dbReference type="OMA" id="TICDKIH"/>
    <dbReference type="OrthoDB" id="9991235at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008832">
        <property type="term" value="F:dGTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006203">
        <property type="term" value="P:dGTP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.10">
        <property type="entry name" value="Hypothetical protein af1432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050135">
        <property type="entry name" value="dGTPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11373">
        <property type="entry name" value="DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11373:SF4">
        <property type="entry name" value="DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD/PDEase" evidence="1">
        <location>
            <begin position="344"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="763" mass="89889" checksum="B06EB1198F641249" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWW3</accession>
    <name>A0A1J1GWW3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GAS8-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00463100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529854.1">
        <property type="nucleotide sequence ID" value="XM_028673397.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWW3"/>
    <dbReference type="GeneID" id="39733164"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00463100"/>
    <dbReference type="OMA" id="SVFYNFQ"/>
    <dbReference type="OrthoDB" id="392761at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031514">
        <property type="term" value="C:motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048870">
        <property type="term" value="P:cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039308">
        <property type="entry name" value="GAS8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025593">
        <property type="entry name" value="GAS8_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31543">
        <property type="entry name" value="DYNEIN REGULATORY COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31543:SF1">
        <property type="entry name" value="HECT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13851">
        <property type="entry name" value="GAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Growth arrest-specific protein 8" evidence="2">
        <location>
            <begin position="218"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="31"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="279"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="445" mass="54046" checksum="4AF20645C9413D6B" modified="2017-02-15" version="1">MNKNKLNKNKLVKSKVNKLKKLSNGEIENLIKNKKEELTRTIQKKRLLEKRLDEKNNELDNFKKEYNEIKNKVDSINKDCEKCNEKVKEEKSIIRKKSIFYNFQNSEELKKLKKEKEELKTLIDKRHEETMNNLMSYIEKQRIDLDYEKNKNFDEINELNISSNLKIRKIEELFTKYLNEFENDKKEEMVDMLENYSIMERNEIIYLKNLYNDHIKNINEIHMNVLQNYKKYYIDRIKENINKIKLLKKKINELEICDKEIKNDLNIYNDQNCSIIEDIKNLEIKRENLEKDLKFYSKDFIMHKNLELIYNESDIYIKNLKLFSQNSKEKINEIEKELKILSEDIKVDEYFENVKNKNILLKKEIENIDIDLDKVNEQLTSFINENNIKKEDVLRVKKGINLCIKTYNKEYDNLLYAEKKIKNKIKDNVNIYEKKLKDIDIKKDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX98</accession>
    <name>A0A1J1GX98_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Profilin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PFN</name>
        <name evidence="3" type="ORF">PGAL8A_00445300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds to proline rich sequences in various regulatory formin-like proteins and also to membrane phospholipids. Binds to actin and affects the structure of the cytoskeleton.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Binds actin.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the profilin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529675.1">
        <property type="nucleotide sequence ID" value="XM_028673197.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX98"/>
    <dbReference type="GeneID" id="39732986"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00445300"/>
    <dbReference type="OMA" id="DKWTLFY"/>
    <dbReference type="OrthoDB" id="421374at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015629">
        <property type="term" value="C:actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003785">
        <property type="term" value="F:actin monomer binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060327">
        <property type="term" value="P:cytoplasmic actin-based contraction involved in cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.30">
        <property type="entry name" value="Dynein light chain 2a, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048278">
        <property type="entry name" value="PFN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036140">
        <property type="entry name" value="PFN_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016814">
        <property type="entry name" value="Profilin_apicomplexa"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00235">
        <property type="entry name" value="Profilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF022993">
        <property type="entry name" value="Profilin_apicomplexa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55770">
        <property type="entry name" value="Profilin (actin-binding protein)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="1" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="site" description="Interaction with Pro-rich sequence" evidence="2">
        <location>
            <position position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR022993-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="171" mass="19175" checksum="EAEB4F70277FCDAA" modified="2017-02-15" version="1">MEGEYSWENYLNDRLLATNQVSAAGLASEEDGVVYACVAQADENDPNFDKWSLFYKEDYEIEIEEENGDKIKKTINEGQTLLTVFKEGYAPDGVWLGGTKFQFINIDRDLDFEGYTFDVATCAKLKGGLHLIKIPGGNILVALYDEEKEHDRGNSKIAALTFAKELAENSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXE7</accession>
    <name>A0A1J1GXE7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00317800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528773.1">
        <property type="nucleotide sequence ID" value="XM_028672195.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXE7"/>
    <dbReference type="GeneID" id="39731711"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00317800"/>
    <dbReference type="OMA" id="KMPFKSE"/>
    <dbReference type="OrthoDB" id="391559at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="159" mass="19306" checksum="70E4329754AC5E8D" modified="2017-02-15" version="1">MNRERLEKERLLQRNEKHIKNIVVDNIIADEKCKNNDNTYLRKKDAEYNDFKCKEKQKLKEYIKIENRRKENLDRDENRWKKVELSVQNEIDKTKKLQQMSFKSEKNKSKCSHDIINHEFINYEESMKLEKKKNACILNRRKFLSEVNGSHNPITAIHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXJ4</accession>
    <name>A0A1J1GXJ4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DnaJ protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00294100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528544.1">
        <property type="nucleotide sequence ID" value="XM_028671941.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXJ4"/>
    <dbReference type="GeneID" id="39731474"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00294100"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="1">
        <location>
            <begin position="14"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="312" mass="38057" checksum="DB9AD9BA622DBF8C" modified="2017-02-15" version="1">METSFIPKELIGKDIYKILGLTINDSTKENIKNIIRKKYLKCALILHPDKKDFNFKVEEKDKYAENFNILKSAYEFLMNEKLRKKYNLYVQKKIKKNTPINNTSLNRYLDKKKFVTYQNQKLFYKKKLEEKEKLKCTPSNNEKEQHNLNKEIDLKKIKKQNEEFMKKSIQENIKKKKYIHDNNKLIEIYLDDYDNNINLLKLYIKKKYFLNFFINFNFLKYYLNLNDEEKENKRKVGYIIFSHRFETIRAFIYYKKNLDKINNNFKLKLLIPCNEDKEMYDEKIQESENIDEMMNEMVDELDKIFSTGIDNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXR0</accession>
    <name>A0A1J1GXR0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00485100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530074.1">
        <property type="nucleotide sequence ID" value="XM_028673641.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXR0"/>
    <dbReference type="GeneID" id="39733384"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00485100"/>
    <dbReference type="OMA" id="WPWWLEK"/>
    <dbReference type="OrthoDB" id="390041at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="74" mass="8947" checksum="56D8CC14ACE02EA2" modified="2017-02-15" version="1">MGKYNLIFKKNWFTKSIFGTVGIFVILDQLARYQYDIPEYRNPNLTMWSWWLEKVNLKRLGINQNNSDNDRENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXR9</accession>
    <name>A0A1J1GXR9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00485900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530082.1">
        <property type="nucleotide sequence ID" value="XM_028673651.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733392"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00485900"/>
    <dbReference type="OMA" id="DNDEHID"/>
    <dbReference type="OrthoDB" id="372958at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1418"/>
            <end position="1437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1483"/>
            <end position="1506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1552"/>
            <end position="1597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1637"/>
            <end position="1675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1705"/>
            <end position="1758"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="997"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1485"/>
            <end position="1506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2042" mass="240187" checksum="37902CDE282996D3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXS3</accession>
    <name>A0A1J1GXS3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Autophagy protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ATG5</name>
        <name evidence="5" type="ORF">PGAL8A_00302000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in autophagic vesicle formation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Conjugated with ATG12.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Preautophagosomal structure membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATG5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528616.1">
        <property type="nucleotide sequence ID" value="XM_028672022.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXS3"/>
    <dbReference type="GeneID" id="39731553"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00302000"/>
    <dbReference type="OMA" id="LKTPLYW"/>
    <dbReference type="OrthoDB" id="272162at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034274">
        <property type="term" value="C:Atg12-Atg5-Atg16 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005776">
        <property type="term" value="C:autophagosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044233">
        <property type="term" value="C:mitochondria-associated endoplasmic reticulum membrane contact site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061908">
        <property type="term" value="C:phagophore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019776">
        <property type="term" value="F:Atg8-family ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006995">
        <property type="term" value="P:cellular response to nitrogen starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007239">
        <property type="entry name" value="Atg5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048939">
        <property type="entry name" value="ATG5_UblA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042527">
        <property type="entry name" value="Atg5_UblA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048318">
        <property type="entry name" value="ATG5_UblB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13040">
        <property type="entry name" value="AUTOPHAGY PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13040:SF2">
        <property type="entry name" value="AUTOPHAGY PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20638">
        <property type="entry name" value="ATG5_UblA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04106">
        <property type="entry name" value="ATG5_UblB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0072">Autophagy</keyword>
    <keyword evidence="1" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Autophagy protein ATG5 UblA" evidence="4">
        <location>
            <begin position="26"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="Autophagy protein ATG5 UblB" evidence="3">
        <location>
            <begin position="594"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="517"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="517"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF20638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="768" mass="91736" checksum="11CCECD5BD240A36" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXT4</accession>
    <name>A0A1J1GXT4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00469100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529913.1">
        <property type="nucleotide sequence ID" value="XM_028673463.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXT4"/>
    <dbReference type="GeneID" id="39733224"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00469100"/>
    <dbReference type="OMA" id="KCENSKY"/>
    <dbReference type="OrthoDB" id="370317at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="257" mass="30821" checksum="9EC814149E991FD8" modified="2017-02-15" version="1">MKKISDFYAYSKNKSTTVLNLKKKVEIDKKKNESCWFKNLYCNFEKTKKDTFEYITEKKKQWKIKFSSLKFPYFKLNNSKYGHFPWYKKLYYLIRDQIYNLLKVTDGKMEEAKIEHNVNENKTHREFYSEEKFDNKSKEIYENSNDSIFYKYSKKLKKTKTNETYFGERSQSEFIKRNMSSSVIPIKTNGSVVDENMLKDTSSMRTVHEEDFCDAKETKEIDSNIILNKDSYNFLNVANSPKFNIKNTWEKLSGFIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXU8</accession>
    <name>A0A1J1GXU8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00333500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528925.1">
        <property type="nucleotide sequence ID" value="XM_028672365.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXU8"/>
    <dbReference type="GeneID" id="39731865"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00333500"/>
    <dbReference type="OMA" id="IYIAKDI"/>
    <dbReference type="OrthoDB" id="370088at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="588" mass="71937" checksum="5E8CB1B0A43A7F22" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYG3</accession>
    <name>A0A1J1GYG3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Malonyl CoA-acyl carrier protein transacylase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00508200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530310.1">
        <property type="nucleotide sequence ID" value="XM_028673904.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYG3"/>
    <dbReference type="GeneID" id="39733615"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00508200"/>
    <dbReference type="OMA" id="AANYNCP"/>
    <dbReference type="OrthoDB" id="541883at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.250">
        <property type="entry name" value="Malonyl-CoA ACP transacylase, ACP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="entry name" value="Malonyl-Coenzyme A Acyl Carrier Protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052760">
        <property type="entry name" value="Mitochondrial_malonyltrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47170">
        <property type="entry name" value="MALONYL-COA ACP TRANSACYLASE, ACP-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47170:SF2">
        <property type="entry name" value="MALONYL-COA:ACP TRANSACYLASE (MAT) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009618957" evidence="1">
        <location>
            <begin position="26"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="Malonyl-CoA:ACP transacylase (MAT)" evidence="2">
        <location>
            <begin position="97"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="395" mass="45023" checksum="F914129D17D90E31" modified="2017-02-15" version="1">MFLNFNFLLLLILKIIIWNSKKCYTFILKNKEVLTISIVDNKNKNNNRRKLVKDTSTSYEIKDMIISSSENENYIKTKLKEFEKYRIENYSSKYTFFFPGQGEQYISMGANSYDNCKNAKEIYDRASKVLGYNLMDVIKNGPIEKLKDSEIAQPSIYTVSIAAYERLKSENKEITEKLNLCMGYSLGEYSALTCSGSLPFEEGVYLTKERGKAMQNSAKLYEMTTIAVVGLTLDTIYKLIEDVNKEMKDDVFIVSYMTDKKFGLCGKPASMDYLNKLAKEKYKAIFTKKLQISGAFHSSYMFPAKGSLEKVLKQTNFKKLNVPVLSNVDGNAYDDPSIIKELLLLQLTSPIKINLCLQNILKNGYENGYELGPGSINTNLLKDISKKTKTAIPYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYH2</accession>
    <name>A0A1J1GYH2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00518500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530413.1">
        <property type="nucleotide sequence ID" value="XM_028674018.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733718"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00518500"/>
    <dbReference type="OMA" id="CLEDYYK"/>
    <dbReference type="OrthoDB" id="372793at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1499"/>
            <end position="1523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1769"/>
            <end position="1803"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2873"/>
            <end position="2894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1504"/>
            <end position="1523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1783"/>
            <end position="1803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2882"/>
            <end position="2894"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2919" mass="346996" checksum="CF50A344F83FB5E3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYI2</accession>
    <name>A0A1J1GYI2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00519300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530421.1">
        <property type="nucleotide sequence ID" value="XM_028674027.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYI2"/>
    <dbReference type="GeneID" id="39733726"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00519300"/>
    <dbReference type="OMA" id="NTKEHVN"/>
    <dbReference type="OrthoDB" id="366232at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="218"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="609" mass="72623" checksum="E5ABFE94073F1E91" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYI4</accession>
    <name>A0A1J1GYI4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Selenoprotein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Sel3</name>
        <name evidence="2" type="ORF">PGAL8A_00521000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530435.1">
        <property type="nucleotide sequence ID" value="XM_028674042.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733743"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00521000"/>
    <dbReference type="OrthoDB" id="369631at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0711">Selenium</keyword>
    <keyword evidence="2" id="KW-0712">Selenocysteine</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="non-standard amino acid" description="Selenocysteine" evidence="2">
        <location>
            <position position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="334" mass="40309" checksum="E3AE32436911CA5E" modified="2017-02-15" version="1">MMLKKIYILIVIILYNITSIIVESGUSRKLHIRLPNENDDYLAKLIDIFKDICNYSVNNKKTIKKIIIGSLLSAYSINSLYNSGVTFKKNPHYSFFIPSNKYFKNVFKIIKKNYEIKMDKFTEQKIFEKYFTNVNDSKIMEMYIMNNLINFSNYLPEKIKNEKFYKFLKYREFENFENIFSHVKVLKHEQIFIFHGKLKKYFWLHLPLKYKILKNDNDMYTLIFIPLYKNYSNYIIEIKIQKDKSNVKFVTYIKSNENGKKASSFYIDVIKNIAAYITYDIFDGIDNNIKVLYKRNTKLSKFNFINSKRLLKKDKFKMKFITIPFLKSLKFRIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYJ5</accession>
    <name>A0A1J1GYJ5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00521200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530437.1">
        <property type="nucleotide sequence ID" value="XM_028674045.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733745"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00521200"/>
    <dbReference type="OMA" id="KVCNKSE"/>
    <dbReference type="OrthoDB" id="10607866at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="943"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="883"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="943"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="953"/>
            <end position="965"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1656" mass="199613" checksum="201C7BF0D7DF2E27" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYN2</accession>
    <name>A0A1J1GYN2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Sodium/hydrogen exchanger, Na+, H+ antiporter, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">NHE</name>
        <name evidence="14" type="ORF">PGAL8A_00499500</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530224.1">
        <property type="nucleotide sequence ID" value="XM_028673808.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733528"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00499500"/>
    <dbReference type="OrthoDB" id="441412at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015386">
        <property type="term" value="F:potassium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015385">
        <property type="term" value="F:sodium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051453">
        <property type="term" value="P:regulation of intracellular pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098719">
        <property type="term" value="P:sodium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018422">
        <property type="entry name" value="Cation/H_exchanger_CPA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110">
        <property type="entry name" value="SODIUM/HYDROGEN EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110:SF86">
        <property type="entry name" value="SODIUM_HYDROGEN EXCHANGER 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0915">Sodium</keyword>
    <keyword evidence="9" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="164"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="193"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="274"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="303"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="328"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="353"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="385"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="419"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="457"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="491"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="13">
        <location>
            <begin position="116"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="618"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="920"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="1123"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="628"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="639"/>
            <end position="648"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG97423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1513" mass="177117" checksum="D04A088BAA3DAADC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYU5</accession>
    <name>A0A1J1GYU5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00022000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000106">
        <property type="protein sequence ID" value="CRG97409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530211.1">
        <property type="nucleotide sequence ID" value="XM_028673794.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYU5"/>
    <dbReference type="GeneID" id="39728743"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00022000"/>
    <dbReference type="OMA" id="EREFMKE"/>
    <dbReference type="OrthoDB" id="383264at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="88"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="267" mass="33472" checksum="B9F360BC11DA349D" modified="2017-02-15" version="1">MSEKWKNEEWFINLKKEWGKEQEKYDELRKSEISEIEAGKNPMLEKQKRIWKEWLKKQRKWFILHSEEDWFNNLLDEYEKEEREEGITKKDENESKEIHENIEELKQEGDEEIEKNRKKRDKLIQNVLIEIHMTLLEECMKDELQNEKEYFFKKMVEELRIQENLDEDVNILEIEKKSRNIILNNDKEKIEEWKKKKWFIELILEMKNKEREFMKEVYKDIIAKKNEDRIRNPMLERQKIIWKKHCEDILRRWIEKNNKECFTSVIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYV7</accession>
    <name>A0A1J1GYV7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00371300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529293.1">
        <property type="nucleotide sequence ID" value="XM_028672774.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYV7"/>
    <dbReference type="GeneID" id="39732243"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00371300"/>
    <dbReference type="OMA" id="HVHPWES"/>
    <dbReference type="OrthoDB" id="332863at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15032">
        <property type="entry name" value="N-ACYL-PHOSPHATIDYLETHANOLAMINE-HYDROLYZING PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15032:SF4">
        <property type="entry name" value="N-ACYL-PHOSPHATIDYLETHANOLAMINE-HYDROLYZING PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="2">
        <location>
            <begin position="308"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="770" mass="91732" checksum="EB2E2DAEBFC088C8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYV8</accession>
    <name>A0A1J1GYV8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SnoRNA-associated small subunit rRNA processing, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00531800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530541.1">
        <property type="nucleotide sequence ID" value="XM_028674160.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYV8"/>
    <dbReference type="GeneID" id="39733851"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00531800"/>
    <dbReference type="OMA" id="NDECENM"/>
    <dbReference type="OrthoDB" id="439639at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12320">
        <property type="entry name" value="RRM6_RBM19_RRM5_MRD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050907">
        <property type="entry name" value="SRSF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23147">
        <property type="entry name" value="SERINE/ARGININE RICH SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="26"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="295"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="612"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="741"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="858"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="267"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="359"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="949"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="204"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="554"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="359"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="382"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="964"/>
            <end position="982"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="994" mass="116920" checksum="129F7AC1237B6B2A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYZ0</accession>
    <name>A0A1J1GYZ0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Heterochromatin protein 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">HP1</name>
        <name evidence="5" type="ORF">PGAL8A_00535000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530573.1">
        <property type="nucleotide sequence ID" value="XM_028674195.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYZ0"/>
    <dbReference type="GeneID" id="39733883"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00535000"/>
    <dbReference type="OMA" id="ENMTHLP"/>
    <dbReference type="OrthoDB" id="1918685at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023779">
        <property type="entry name" value="Chromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051219">
        <property type="entry name" value="Heterochromatin_chromo-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22812">
        <property type="entry name" value="CHROMOBOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00598">
        <property type="entry name" value="CHROMO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="4">
        <location>
            <begin position="8"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="64"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="64"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="75"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="122"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="264" mass="30911" checksum="54A8340DB697DEE7" modified="2017-02-15" version="1">MTASDEEFEIGDILEIKKKRNGFLYLVKWKGYSDDENTWEPESNLTHLTSFKKKMENLKMNYLKKNDTPNENKNSKNHILSIQDDSSIKSKSRSSSISKKKNNKKIVTNKLESKKNISHSDNSLKKSDKEDNESIKQETNSNDSNLLNVEDVYSVRIKNRKMEFLASLKNASPQWVEESNIRRTGHLNIKVNDFKKYIRRKKSAKGNRIVIKNLHNVGDELYISVIHNINNKEIHSLYPSKVIEYIYPQELLNFLLSRLRYRTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZC9</accession>
    <name>A0A1J1GZC9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00523100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530456.1">
        <property type="nucleotide sequence ID" value="XM_028674066.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733764"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00523100"/>
    <dbReference type="OMA" id="NICLECM"/>
    <dbReference type="OrthoDB" id="364645at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005227">
        <property type="term" value="F:calcium-activated cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045122">
        <property type="entry name" value="Csc1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018">
        <property type="entry name" value="PROBABLE MEMBRANE PROTEIN DUF221-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018:SF5">
        <property type="entry name" value="RE44586P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="194"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="801"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="848"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="890"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="955"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1030"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1067"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1097"/>
            <end position="1120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="734"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1308"/>
            <end position="1394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1308"/>
            <end position="1329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1330"/>
            <end position="1351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1352"/>
            <end position="1381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1382"/>
            <end position="1394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1575" mass="189324" checksum="88E09E62D29CCB88" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZE2</accession>
    <name>A0A1J1GZE2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00361100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529192.1">
        <property type="nucleotide sequence ID" value="XM_028672662.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZE2"/>
    <dbReference type="GeneID" id="39732141"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00361100"/>
    <dbReference type="OMA" id="DKYQIFY"/>
    <dbReference type="OrthoDB" id="377727at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="392"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="427"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="555" mass="67316" checksum="C29F74559E4C057E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZU4</accession>
    <name>A0A1J1GZU4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PIR-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00412100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000062">
        <property type="protein sequence ID" value="CRG96539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529344.1">
        <property type="nucleotide sequence ID" value="XM_028672830.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZU4"/>
    <dbReference type="GeneID" id="39732651"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00412100"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="283"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="156"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="200"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="399" mass="44405" checksum="35CA3322363FD988" modified="2017-02-15" version="1">MIIYVYFLVCIFQYFYSINFEIGKNNLKTELCLRCGRILAEQQRGTSSRRVRSTNSHEKFLDIWLKYIEEDFFDNLNKLTESFTPNNTQNFLEWMYQKGRNITNVLNLSSDPEVKSFFNKTLTSWRGFTDKVLLDKALDTFIQERMLNAANVTTNLNGSSSTSASSHNSPSTSISLPTPTESSNITTLPISTLSPESTVSPTTALSSDSDLSSSTSFLPTISSDSHNNSTTPIKNTSDSPTILSTNEINTATVLTNNPTALIPTQHGGGLTGATCTGLLCGPAFVALPVSVALLGGVFFFVLLYMYTPVGKFLGRDNPKKKKAKKRLNEIPMECINSPKLLKVKRTENAKRSRLHRFLRAFGYDKNFPYIDEDIPSDQASLTFLAIKGLAMWRIHSCAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZW0</accession>
    <name>A0A1J1GZW0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Reticulocyte binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00413800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000068">
        <property type="protein sequence ID" value="CRG96556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529360.1">
        <property type="nucleotide sequence ID" value="XM_028672848.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZW0"/>
    <dbReference type="GeneID" id="39732668"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00413800"/>
    <dbReference type="OMA" id="YIVPENC"/>
    <dbReference type="OrthoDB" id="386780at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012113933" evidence="2">
        <location>
            <begin position="24"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="210"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="572"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="789"/>
            <end position="826"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="849" mass="100887" checksum="5CE0218F124B198F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZW2</accession>
    <name>A0A1J1GZW2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00042500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG97996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530793.1">
        <property type="nucleotide sequence ID" value="XM_028674441.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZW2"/>
    <dbReference type="GeneID" id="39728950"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00042500"/>
    <dbReference type="OMA" id="EVDANCC"/>
    <dbReference type="OrthoDB" id="10542379at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="49"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="167"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="200" mass="24201" checksum="C253046B72AF887F" modified="2017-02-15" version="1">MISIDGSFRYSLIKFLIITFSVKVKKFYVYSSYNNIEILGKKNKIKRRLLVLLILYLFSLSIIFKGVIILRLQFNKNHIRKLAEIEVDANCCESNLNNVRVSCHSPLRKYIDERVKMRKWSKVKKRTLKWIKNSYCENWTEQDLFRYNLHWKRCEATMRDIIKCLSSNQQKRIIKDLNEMNAKWEERLNEKDNKQNSEHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H034</accession>
    <name>A0A1J1H034_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-i protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00053200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000137">
        <property type="protein sequence ID" value="CRG98097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530894.1">
        <property type="nucleotide sequence ID" value="XM_028674553.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H034"/>
    <dbReference type="GeneID" id="39729057"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00053200"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="120"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="201"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="242" mass="28612" checksum="7FEEF6715834C687" modified="2017-02-15" version="1">MDLNLSDAINIGYSETLNEGDSTAGFAHREIKDATVSIPENPLYDDLNSCDAIQNPSKDINLDSATPINVLYKKSLNIFQLAIIIISFLRFARAHSPKLKAKHERDRLQKIWDNSSKKMKGDLEKKMLKEKKKMEDREKKLLKKKKEMEEWEKGVLREKAVWERRTQKEKQECGESMLKQLEEWEKRILQKGEDWEKRNIIEKEQLEKEILKNKEEGEEKMLKIMKKLEKKILKEKKSGKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0I1</accession>
    <name>A0A1J1H0I1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="19">ATP-dependent zinc metalloprotease FTSH 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">FTSH1</name>
        <name evidence="19" type="ORF">PGAL8A_00461400</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the peptidase M41 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the N-terminal section; belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529837.1">
        <property type="nucleotide sequence ID" value="XM_028673379.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0I1"/>
    <dbReference type="GeneID" id="39733147"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00461400"/>
    <dbReference type="OMA" id="CFGFAIW"/>
    <dbReference type="OrthoDB" id="1413014at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19501">
        <property type="entry name" value="RecA-like_FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000001">
        <property type="entry name" value="ATP-dependent zinc metalloprotease FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.760:FF:000002">
        <property type="entry name" value="ATP-dependent zinc metalloprotease FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000277">
        <property type="entry name" value="ATP-dependent zinc metalloprotease FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="entry name" value="Peptidase M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01458">
        <property type="entry name" value="FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005936">
        <property type="entry name" value="FtsH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01241">
        <property type="entry name" value="FtsH_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076:SF97">
        <property type="entry name" value="ATP-DEPENDENT ZINC METALLOPROTEASE YME1L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076">
        <property type="entry name" value="METALLOPROTEASE M41 FTSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="FtsH protease domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14 19" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="6 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="18">
        <location>
            <begin position="179"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="105"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="585"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="782"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="115"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="587"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="603"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="692"/>
            <end position="709"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="CRG97034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="962" mass="110760" checksum="4D7DEF5842C1F71B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0R2</accession>
    <name>A0A1J1H0R2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Adenylate kinase-like protein 2, putative</fullName>
            <ecNumber evidence="4">2.7.4.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">AKLP2</name>
        <name evidence="4" type="ORF">PGAL8A_00445000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.3" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529672.1">
        <property type="nucleotide sequence ID" value="XM_028673194.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0R2"/>
    <dbReference type="GeneID" id="39732983"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00445000"/>
    <dbReference type="OrthoDB" id="522106at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:AMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="274" mass="32029" checksum="9BE9AEC04779872A" modified="2017-02-15" version="1">METLLDSETLKKFEEETNEYIRKKKVKKLFDIILKNVLINKPENIYFYIYSNIYSFLLNKIFIIGPPLLKITSVLSSSISKTFDYYHISISELIKSHISYDINNIEENSINKKLINDDLVSSIIKTTLSNLDAKKKRGYVVEGFPSTNIQANNCLQYLPSHVIVLFADEEYIYEKYEEENDTKIFSNIHNNIEENVELFEVKEVDPSPLKDKVKVYLRNVSGVLEVLENNKEVINLRDYNERDLIDYVTNLVTQNKDEWNSVLEDNSLDVSEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H104</accession>
    <name>A0A1J1H104_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Vacuolar proton pump subunit B</fullName>
            <shortName evidence="5">V-ATPase subunit B</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Vacuolar proton pump subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00056800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex attached to an integral membrane V0 proton pore complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530930.1">
        <property type="nucleotide sequence ID" value="XM_028674593.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H104"/>
    <dbReference type="GeneID" id="39729093"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00056800"/>
    <dbReference type="OMA" id="EDHPQVM"/>
    <dbReference type="OrthoDB" id="1735853at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033180">
        <property type="term" value="C:proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046034">
        <property type="term" value="P:ATP metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18112">
        <property type="entry name" value="ATP-synt_V_A-type_beta_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18118">
        <property type="entry name" value="ATP-synt_V_A-type_beta_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01135">
        <property type="entry name" value="V_A-ATPase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12240:FF:000003">
        <property type="entry name" value="V-type proton ATPase subunit B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00310">
        <property type="entry name" value="ATP_synth_B_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055190">
        <property type="entry name" value="ATP-synt_VA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005723">
        <property type="entry name" value="ATPase_V1-cplx_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022879">
        <property type="entry name" value="V-ATPase_su_B/beta"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003235">
        <property type="entry name" value="PRK04196.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01040">
        <property type="entry name" value="V-ATPase_V1_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43389">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43389:SF4">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22919">
        <property type="entry name" value="ATP-synt_VA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039114">
        <property type="entry name" value="V-ATPsynth_beta/V-ATPase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit N-terminal" evidence="7">
        <location>
            <begin position="35"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding" evidence="6">
        <location>
            <begin position="158"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="ATP synthase A/B type C-terminal" evidence="8">
        <location>
            <begin position="389"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU366021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF22919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG98133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="494" mass="55761" checksum="583E08D85B8C3B99" modified="2017-02-15" version="1">MSKVPIKTKIEASRVNALAAVRNYKVCPRLEYKTISGVQGPLVIIEDVKFPKYSEIVTIHLSDNSTRQGQILEVCGKKAVIQVFEGTSGIDNKNSYVEVSGDILKMPISDEMLGRVFNGSGKPIDKGPNILADDFIDINGNPINPQCRVYPKEMIQTGISTIDVMNSIVRGQKIPLFSAAGLPHNEIGAQICRQASLVQGKDVLDHSDDNFAVVFGAMGVNMETARYFRQDFEENGKMERVVLFLNLANDPTIERILTPRLALTTAEYLAFEKEMHVFVILTDMSSYADALREVSSAREEVPGRRGYPGYMYSDLSTIYERAGRVEGRNGSITQFPILTMPNDDITHPIPDLTGYITEGQIFVDRNLYNRQIYPPINVLPSLSRLMKSGIGHNMTRIDHPYVSDQLYSNYAIAQDVKAMKAVIGEEALSNDDILYLEFLDKFEKRFITQNTYECRDIYQSLDIAWELLRIFPEDMLKKIKSDILSKYYPRHHAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H120</accession>
    <name>A0A1J1H120_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sporozoite invasion-associated protein 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">SIAP1</name>
        <name evidence="2" type="ORF">PGAL8A_00059200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530954.1">
        <property type="nucleotide sequence ID" value="XM_028674619.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H120"/>
    <dbReference type="GeneID" id="39729117"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00059200"/>
    <dbReference type="OrthoDB" id="360533at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012588424" evidence="1">
        <location>
            <begin position="22"/>
            <end position="983"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="983" mass="113118" checksum="A36E81AD0E8E5187" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1H0</accession>
    <name>A0A1J1H1H0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">S-antigen protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00495000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">S antigens are soluble heat-stable proteins present in the sera of some infected individuals.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Parasitophorous vacuole</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530173.1">
        <property type="nucleotide sequence ID" value="XM_028673751.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1H0"/>
    <dbReference type="GeneID" id="39733483"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00495000"/>
    <dbReference type="OMA" id="CENIAKC"/>
    <dbReference type="OrthoDB" id="392935at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020003">
        <property type="term" value="C:symbiont-containing vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008825">
        <property type="entry name" value="S-antigen"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05756">
        <property type="entry name" value="S-antigen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013312109" description="S-antigen protein" evidence="6">
        <location>
            <begin position="20"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="S-antigen" evidence="7">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="94"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="157"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="180"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="226"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="242"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="256"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="280"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="296"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="313"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="384"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="421"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="510" mass="57233" checksum="E3CD41D6620163FC" modified="2017-02-15" version="1">MKKILSISFYLFFLNLYICENNENLIDKGENIKNKDSQKPNLRNGNLDNYLFLKQNLSDSVKGYEYLQDIGNFYNSEKNYAIQGQTEVDARSEITQNQQGTNEPGEDLKKVDLEENPPTQLGDGLQKALEGDQGSKEPISSPSELQVKTDPSPMSPNKEDHMENIELTVKAEGDPEVQAETVNGITPSPIQSSDTGSGSTAGGDHNKGSPAGSHTTNGNLGESVGNTQQQNQTLQEPQLIEKSLKEGEKEQLQADLEQQSPSQTQKGTTTGKIELIESPERDEDDDNEEEEEEVEEVVKPPAEKKVNVLESIEVADGELGDLSEDEEEEEEEHEVEEEEEEEDEDEESEEQRDEGEEELDYSDIEEDEDEDDEEGDSEEDEDSVVDKETGDRQMEDGDLLEEDRQPPNEISPEQETPDTISEERRKQEESRRTEEGQSHENSEQKQKEIITPSNDSSAHKSLIKDFKDDNKVKKEAETKVKNMINLIGDSGVADTLKDLAKDMAQIFLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H361</accession>
    <name>A0A1J1H361_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">MORN repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00036200</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
            <location evidence="1">Flagellum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530724.1">
        <property type="nucleotide sequence ID" value="XM_028674363.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728886"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00036200"/>
    <dbReference type="OMA" id="QKNEHKG"/>
    <dbReference type="OrthoDB" id="203073at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031514">
        <property type="term" value="C:motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46613">
        <property type="entry name" value="RADIAL SPOKE HEAD 10 HOMOLOG B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46613:SF1">
        <property type="entry name" value="RADIAL SPOKE HEAD 10 HOMOLOG B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5" id="KW-0282">Flagellum</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1372"/>
            <end position="1393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1413"/>
            <end position="1429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1078"/>
            <end position="1121"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="194"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1090"/>
            <end position="1104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1105"/>
            <end position="1116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG97925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1435" mass="174240" checksum="BEE411ABDCC1C140" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H383</accession>
    <name>A0A1J1H383_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00038600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530748.1">
        <property type="nucleotide sequence ID" value="XM_028674390.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H383"/>
    <dbReference type="GeneID" id="39728910"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00038600"/>
    <dbReference type="OMA" id="THKEMCT"/>
    <dbReference type="OrthoDB" id="371790at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="455" mass="54903" checksum="D2A90E75EA6EFB3B" modified="2017-02-15" version="1">MNDFSILFIRKLVPCVSLNKINSVYLLKHLENVCEHIFQENKYNVKKPIKNCFSNVFLKKKGKKKKKITNSVISTERSNKIFRQVYQYFDKATVLLPELGPNGILRLLYALLKVKNFERNKAKKITVLKYIEYYILRSSINDEIFNFWKHFTINDAVLLFKMFIMNDYFSYDLLNTLTNKIIDNIKCSVPSDIVIFLSAYHTYKQKIKYKRYKIKEIFLTYNSLKILYNEVVNNFDLTNKEICNFIMFYSLYGKSISLDEKIMIYFKVVQHIEKTMLIYSPEQIKNLIISLFRIHNFTFDNTFNENIYKCYDKTLTNEILKKLFKLYNYRNIDVKIEDELNILDQSLKNKYYDYNSLEDMIFNIKNNISNLKNKNQIKYINLVIKLLNVYRNENNIHISSQKKFNYFMLRHILSESLSFFNLKYKFLPWNLMHIVLKYQLNDAKKILPYKYELKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3J0</accession>
    <name>A0A1J1H3J0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">GTP-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00034800</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530711.1">
        <property type="nucleotide sequence ID" value="XM_028674349.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3J0"/>
    <dbReference type="GeneID" id="39728872"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00034800"/>
    <dbReference type="OMA" id="CLIECTE"/>
    <dbReference type="OrthoDB" id="391988at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01876">
        <property type="entry name" value="YihA_EngB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00321">
        <property type="entry name" value="GTPase_EngB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030393">
        <property type="entry name" value="G_ENGB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019987">
        <property type="entry name" value="GTP-bd_ribosome_bio_YsxC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03598">
        <property type="entry name" value="GTPase_YsxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11649:SF13">
        <property type="entry name" value="ENGB-TYPE G DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11649">
        <property type="entry name" value="MSS1/TRME-RELATED GTP-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51706">
        <property type="entry name" value="G_ENGB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0717">Septation</keyword>
    <feature type="domain" description="EngB-type G" evidence="10">
        <location>
            <begin position="75"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG97912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="284" mass="33009" checksum="31EE4C7BAB1E487D" modified="2017-02-15" version="1">MISMSKCFLLKNEKSTKITPYLAKPFININFLNTEESPYWLNYEHIKKSNIIFSSKIIAYPVYVAQTIHKYKPTNIPQIAIFGRSNVGKSSLINALLNFREVAQASKTPGRTRHLFIFNLLNYLSIVDLPGYGYAKVSKDLRDNWSILIEEYLNRAKNLKRALCLIECTELFSTYDFILLDMLITKKIPFQIIITKIDKLKANELHNLMIKVLSVIDNYKKKVNLFNENAYKKNNNFDKEIYEFNINEYLHNVSSLKCFGIQELRANLSLIALDNLNSQKLKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3K0</accession>
    <name>A0A1J1H3K0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="16">RNA-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PGAL8A_00036500</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRM CWC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530727.1">
        <property type="nucleotide sequence ID" value="XM_028674367.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3K0"/>
    <dbReference type="GeneID" id="39728889"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00036500"/>
    <dbReference type="OMA" id="KINDRCN"/>
    <dbReference type="OrthoDB" id="10251848at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071006">
        <property type="term" value="C:U2-type catalytic step 1 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071007">
        <property type="term" value="C:U2-type catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036002">
        <property type="term" value="F:pre-mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017070">
        <property type="term" value="F:U6 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12360">
        <property type="entry name" value="RRM_cwf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000718">
        <property type="entry name" value="Pre-mRNA-splicing factor CWC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039171">
        <property type="entry name" value="Cwc2/Slt11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034181">
        <property type="entry name" value="Cwc2_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032297">
        <property type="entry name" value="Torus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14089:SF2">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR CWC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14089">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR RBM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16131">
        <property type="entry name" value="Torus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="7 12" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="15">
        <location>
            <begin position="599"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="14">
        <location>
            <begin position="669"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="12">
        <location>
            <begin position="599"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="174"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="8"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="184"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="247"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="CRG97928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="841" mass="99960" checksum="C9FECD2AC309CF27" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3X3</accession>
    <name>A0A1J1H3X3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">BUD32</name>
        <name evidence="12" type="ORF">PGAL8A_00048500</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. BUD32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530847.1">
        <property type="nucleotide sequence ID" value="XM_028674501.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3X3"/>
    <dbReference type="GeneID" id="39729010"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00048500"/>
    <dbReference type="OMA" id="HKLYMEY"/>
    <dbReference type="OrthoDB" id="3399at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000408">
        <property type="term" value="C:EKC/KEOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070525">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000951">
        <property type="entry name" value="EKC/KEOPS complex subunit BUD32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022495">
        <property type="entry name" value="Bud32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03724">
        <property type="entry name" value="arch_bud32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12209:SF0">
        <property type="entry name" value="EKC_KEOPS COMPLEX SUBUNIT TP53RK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12209">
        <property type="entry name" value="NON-SPECIFIC SERINE/THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="1"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG98050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="233" mass="27107" checksum="59B2195FFC21CBE6" modified="2017-02-15" version="1">MDNVLISSGSDARIYKCDFIGKEAVKKVIYRKFYRHRKIDAKIRKLRVSNEIKFTKRLASLNIDIPFLYFVDVKEKSLYFEYIKGCTINNILKNIKEYEPNIAKCIGMILARIHNGNIIHGDFTTSNLILRNSYINENKIYDYSNNSIYKLNDLDTIKLCVIDFGLSFLSSSVEDKAVDLFVLLKAIKSFHSEFSSLEEDILRGYEMKSNNFNEISKKLEIVKQRGRKRPMVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2012-07-11" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>I2FKD3</accession>
    <name>I2FKD3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">dihydrolipoyllysine-residue succinyltransferase</fullName>
            <ecNumber evidence="4">2.3.1.61</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">2-oxoglutarate dehydrogenase complex component E2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">DLST</name>
        <name evidence="13" type="ORF">PGAL8A_00517100</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Gene" volume="502" first="36" last="39">
            <title>Age of the last common ancestor of extant Plasmodium parasite lineages.</title>
            <authorList>
                <person name="Hayakawa T."/>
                <person name="Tachibana S."/>
                <person name="Hikosaka K."/>
                <person name="Arisue N."/>
                <person name="Matsui A."/>
                <person name="Horii T."/>
                <person name="Tanabe K."/>
            </authorList>
            <dbReference type="PubMed" id="22555021"/>
            <dbReference type="DOI" id="10.1016/j.gene.2012.04.037"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-lysine degradation via saccharopine pathway; glutaryl-CoA from L-lysine: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.61" evidence="4"/>
    <dbReference type="EMBL" id="AB571142">
        <property type="protein sequence ID" value="BAM15618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="I2FKD3"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00517100"/>
    <dbReference type="OMA" id="SMWSEQV"/>
    <dbReference type="OrthoDB" id="5391403at2759"/>
    <dbReference type="UniPathway" id="UPA00868">
        <property type="reaction ID" value="UER00840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045252">
        <property type="term" value="C:oxoglutarate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004149">
        <property type="term" value="F:dihydrolipoyllysine-residue succinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033512">
        <property type="term" value="P:L-lysine catabolic process to acetyl-CoA via saccharopine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.559.10:FF:000007">
        <property type="entry name" value="Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050537">
        <property type="entry name" value="2-oxoacid_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006255">
        <property type="entry name" value="SucB"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004309">
        <property type="entry name" value="PRK05704.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01347">
        <property type="entry name" value="sucB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43416:SF5">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43416">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="11">
        <location>
            <begin position="45"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="168"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAM15618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG97598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="443" mass="50591" checksum="F6138388B98E4B5C" modified="2012-07-11" version="1">MTQNLILRLNKSSLYNLNSVKRTFFSLKSRQNEKYRFVFRRYFSIDTIKVPRLGDSITEGTINEWKKKVGDYVKNDETLAIIDTDKVSVDINSKSSGTLHKIFAEAGDIILVDSPLCEIDTSAKPPENISTTEKKINVNIMKEEVEKEKKTYNESILDEKKSENIVTDEKKSENIATNEKKSENNVIEEKKSEKSTNEDKILEVNYEYVNERTERRVRMLPIRKRIAERLKESQNTCALLTTFNECDMSKAMIFRNELKDTFQKKYGCKLGFVSLFIYASTLALKKMPQVNAFIDNDEIVYKNYIDISVAVATPNGLTVPVIRDCQNKKLPQLEQALSELATKARNNKLSLDDLTGGTFTISNGGVFGSMLSTPIVNMPQSAILGMHTIKNRPVVINNEIVIRPIMYLALTYDHRLLDGRDAVQFLCAIRDYIENPNLMLIEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2006-01-10" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>Q2VL33</accession>
    <name>Q2VL33_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5 6">SES</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ICP</name>
        <name evidence="6" type="ORF">PGAL8A_00424700</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2006" name="Mol. Biochem. Parasitol." volume="148" first="199" last="209">
            <title>A ubiquitous Plasmodium protein displays a unique surface labeling pattern in sporozoites.</title>
            <authorList>
                <person name="LaCrue A.N."/>
                <person name="Sivaguru M."/>
                <person name="Walter M.F."/>
                <person name="Fidock D.A."/>
                <person name="James A.A."/>
                <person name="Beerntsen B.T."/>
            </authorList>
            <dbReference type="PubMed" id="16697061"/>
            <dbReference type="DOI" id="10.1016/j.molbiopara.2006.03.016"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">8A</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="DQ068022">
        <property type="protein sequence ID" value="AAY98514.1"/>
        <property type="molecule type" value="mRNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529471.1">
        <property type="nucleotide sequence ID" value="XM_028672971.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q2VL33"/>
    <dbReference type="GeneID" id="39732779"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00424700"/>
    <dbReference type="OrthoDB" id="371298at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004869">
        <property type="term" value="F:cysteine-type endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2020">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036331">
        <property type="entry name" value="Chagasin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024321">
        <property type="entry name" value="Prot_Inh_falstatin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12628">
        <property type="entry name" value="Inhibitor_I71"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141066">
        <property type="entry name" value="ICP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="1" id="KW-0646">Protease inhibitor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0789">Thiol protease inhibitor</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011423335" evidence="4">
        <location>
            <begin position="22"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="193"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="365"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="202"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="365"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="401"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="424"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="AAY98514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="550" mass="63205" checksum="3339E8B5D426CA01" modified="2006-01-10" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKU9</accession>
    <name>A0A1J1GKU9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transporter, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00071000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525828.1">
        <property type="nucleotide sequence ID" value="XM_028674643.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKU9"/>
    <dbReference type="GeneID" id="39729235"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00071000"/>
    <dbReference type="OMA" id="KMCFNYF"/>
    <dbReference type="OrthoDB" id="409173at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015086">
        <property type="term" value="F:cadmium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034755">
        <property type="term" value="P:iron ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001046">
        <property type="entry name" value="NRAMP_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF037982">
        <property type="entry name" value="Nramp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11706:SF33">
        <property type="entry name" value="NATURAL RESISTANCE-ASSOCIATED MACROPHAGE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11706">
        <property type="entry name" value="SOLUTE CARRIER PROTEIN FAMILY 11 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01566">
        <property type="entry name" value="Nramp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00447">
        <property type="entry name" value="NATRESASSCMP"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="304"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="341"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="381"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="419"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="475"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="514"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="545"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="582"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="613"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="644" mass="74161" checksum="3398F17CFF3B74C2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL08</accession>
    <name>A0A1J1GL08_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00080800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525926.1">
        <property type="nucleotide sequence ID" value="XM_028670533.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729332"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00080800"/>
    <dbReference type="OMA" id="NTNIMEK"/>
    <dbReference type="OrthoDB" id="372732at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1850"/>
            <end position="1877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1866"/>
            <end position="1877"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2384" mass="282547" checksum="8FECCF874C732971" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL95</accession>
    <name>A0A1J1GL95_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Small subunit rRNA processing protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00083300</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ESF2/ABP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525951.1">
        <property type="nucleotide sequence ID" value="XM_028670810.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL95"/>
    <dbReference type="GeneID" id="39729357"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00083300"/>
    <dbReference type="OMA" id="ENTEFHD"/>
    <dbReference type="OrthoDB" id="287393at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000480">
        <property type="term" value="P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000472">
        <property type="term" value="P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034462">
        <property type="term" value="P:small-subunit processome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12263">
        <property type="entry name" value="RRM_ABT1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039119">
        <property type="entry name" value="ABT1/Esf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034353">
        <property type="entry name" value="ABT1/ESF2_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12311">
        <property type="entry name" value="ACTIVATOR OF BASAL TRANSCRIPTION 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12311:SF7">
        <property type="entry name" value="ACTIVATOR OF BASAL TRANSCRIPTION 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="133"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="287"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="48"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="287"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="334" mass="40269" checksum="8D57DEE9E4CD9D42" modified="2017-02-15" version="1">MKKILKFKKNGDIKNQLNEKKIDKKSFKKKKNRDLKKKKEYKINVLKFNNEKNKKNCFEENVKNKKELNNKKEKIINVKDENKLCTNVKFEQNQKLNKEKKIFKKEPSYEEDERFQFNDKLWLEVKKEESKRGIIYLSHIPIGLTPSKIKEIFSKYGSIDKIYLNKIKDEKINIVSKEKNSKRIKYSDGYIEFYDKKDAIKVEKLLNNQMIGGKKRKNILRENFWHIKYLKNFTWNDLVSSVLYRNISRKDRFNFALKNMYKNYEKYLEKNIDKEGYNKKTVSSKFISKKNKKEKKKSPSKNSNKLKFVTLKEEDKKTDKSNTVSSDFLKLLIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLR3</accession>
    <name>A0A1J1GLR3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cyclin-dependent kinases regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00101900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CKS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526135.1">
        <property type="nucleotide sequence ID" value="XM_028672854.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLR3"/>
    <dbReference type="GeneID" id="39729544"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00101900"/>
    <dbReference type="OrthoDB" id="369901at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.170.10">
        <property type="entry name" value="Cyclin-dependent kinase, regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000789">
        <property type="entry name" value="Cyclin-dep_kinase_reg-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036858">
        <property type="entry name" value="Cyclin-dep_kinase_reg-sub_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01111">
        <property type="entry name" value="CKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01084">
        <property type="entry name" value="CKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55637">
        <property type="entry name" value="Cell cycle regulatory proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU311113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="770" mass="92393" checksum="81686D5785882B97" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLS0</accession>
    <name>A0A1J1GLS0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PAP2-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00108100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526198.1">
        <property type="nucleotide sequence ID" value="XM_028673555.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLS0"/>
    <dbReference type="GeneID" id="39729607"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00108100"/>
    <dbReference type="OrthoDB" id="302705at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042392">
        <property type="term" value="F:sphingosine-1-phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14969:SF13">
        <property type="entry name" value="AT30094P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14969">
        <property type="entry name" value="SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="271"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="2">
        <location>
            <begin position="177"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="301" mass="34940" checksum="77AE0DAE42F3EFC0" modified="2017-02-15" version="1">MIQSGHFVSTSKCIGIIIYLVYTGLVQGFYINTYYKVGSEIFPNDNSIEEKFKTYLRSKKRELKPLFINDSNEEKENSLNNVMGDDDSELLGKYPICEAKYKLVDKLKVINFLEKLMEKRKKIIFNKSCLTETYEVLLVTLKNTNDLLSVLATVYGFIPHFLIFIILFGFFITFNKILLYFVLIIPTQMTLNDLILKNIFKMRRPNNSALKSYGMPSGHSSFSYSILTFTVLHLIESHKDKWNIIASLLALITLFPIPWSRVYIEDHTVSQVIVGIILGVILGCLFFLFKRILFKYKYSKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLW8</accession>
    <name>A0A1J1GLW8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00092500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Flagellum axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526043.1">
        <property type="nucleotide sequence ID" value="XM_028671832.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLW8"/>
    <dbReference type="GeneID" id="39729449"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00092500"/>
    <dbReference type="OMA" id="WEYLDLF"/>
    <dbReference type="OrthoDB" id="7760980at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005858">
        <property type="term" value="C:axonemal dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070286">
        <property type="term" value="P:axonemal dynein complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060285">
        <property type="term" value="P:cilium-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003352">
        <property type="term" value="P:regulation of cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039750">
        <property type="entry name" value="DRC1/DRC2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21625:SF0">
        <property type="entry name" value="DYNEIN REGULATORY COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21625">
        <property type="entry name" value="NYD-SP28 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0969">Cilium</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="101"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="207"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="398"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="443" mass="53674" checksum="9A218F2835161E33" modified="2017-02-15" version="1">MIKNNNKKKKDNKKLKKKSNAPKIDTSAQKLLNKKKIDQPPTILRWIQLLRNLKLKQLKKNIDEEISNYEINKNINDKLLLFLNDDLEENKILEKIDELKNSKLSLLVEMHEKNMNNLQKKYEEEIYKMFNDFEQDQTILLKNRNSIIHNINLFYHQLEEEQKLRQNNLKKEELDIMDQIYKNYIAERYISNYKFDKFKEEDKINFNDTLIENKKNLNEENENCKEVKMKYEKNKKCLLSKEKEVHDLESKIDNWKIKLENEIKIYEMQIERLKNEKTQLLNHIRAIKLILQKLEHNDKQRLIDITVNSSNCINKLEENISLANKLINFNNLCRKYETERQKVFSSLDSSHEKKEDIISENEKEEYFKNIKNKNEDDAYLLENFFKRQNKTILDVFILKKELKTLKKKNKEYNKILDELENKVNLNKKVKIKKNEFVIKALEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM21</accession>
    <name>A0A1J1GM21_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">U4/U6.U5 small nuclear ribonucleoprotein 27kDa protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00111000</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May play a role in mRNA splicing.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of a tri-snRNP complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SNUT3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526226.1">
        <property type="nucleotide sequence ID" value="XM_028673866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM21"/>
    <dbReference type="GeneID" id="39729635"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00111000"/>
    <dbReference type="OMA" id="TDNKCHN"/>
    <dbReference type="OrthoDB" id="21368at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013957">
        <property type="entry name" value="SNRNP27"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31077">
        <property type="entry name" value="U4/U6.U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 27 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31077:SF1">
        <property type="entry name" value="U4_U6.U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 27 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08648">
        <property type="entry name" value="SNRNP27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="U4/U6.U5 small nuclear ribonucleoprotein 27kDa protein" evidence="10">
        <location>
            <begin position="403"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="112"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="303"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="118"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="150"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="175"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="227"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="261"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG93404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="458" mass="55650" checksum="A0593287A6FF0B09" modified="2017-02-15" version="1">MESYVNNFDKINNYDEIKNMNISENNEFCKKDIKYETQIPNNGCVMEFSEEKKLNDINENEINLTNKFLPNCNNSEMKVDNYNDGNYQIDEINEVSNDIINSVNEVVYDFNSDSTYGTHEKSRERERHMKSKHRHISKDRKRSRRRDRNRNRSRERSRDRSRYKSRNRSRDRSRYKSRNRSRDRSRHKSRNRSRDKKRDKYRSRSKGRSRDRHRYRKRDRERSIDRHRYKHKDKSVDKHRKRSLDRYNDKHKSRRRISNNRYEKNSKNRDSISYSDDKSDEKGKNNNRFYSNERENDIKRSINNNLIDKVNNENRDYDDLNNNKVNAKLNEVNNNYREQIEINNSEKKLITNDINSSNNIINNNYNQNAHDSNSKEKNTKLCIDEEKNYNALSSENEKEDMSENDMIKKIIGISQFDTTENKCHNQTDLSGINRRTKRKYRQYMNRRGGFNRPLSPSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM24</accession>
    <name>A0A1J1GM24_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein FRA10AC1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00108400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526201.1">
        <property type="nucleotide sequence ID" value="XM_028673588.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM24"/>
    <dbReference type="GeneID" id="39729610"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00108400"/>
    <dbReference type="OMA" id="CPTHTEQ"/>
    <dbReference type="OrthoDB" id="197967at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019129">
        <property type="entry name" value="Folate-sensitive_fs_Fra10Ac1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09725">
        <property type="entry name" value="Fra10Ac1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="239" mass="28798" checksum="37CD99B1295FFEB3" modified="2017-02-15" version="1">MNYINLSGYNIPKKIFDELNAFERHKLMMSLRLLEKEKNKSDNEQYLNDYDILKKKYNFIHDSTEKNSLLQNYYNSICNKYVICDLTKYKESKIGLRWRTEEEIISGKGHIICSSKKCNNTDLKTYEFLFEYIEGGEKKETKVNVRACMDCAYKLHYRKIKEYLKKKEKKKMKRKRRKKRYKKGDSSSECNSPSSAHNPKNSKLKKENLFYVKRKLEKFSLKTKEDKNDNNTYFHDLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM77</accession>
    <name>A0A1J1GM77_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00120400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526319.1">
        <property type="nucleotide sequence ID" value="XM_028674716.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729729"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00120400"/>
    <dbReference type="OMA" id="DNNSRED"/>
    <dbReference type="OrthoDB" id="387381at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="416"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="515"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1291" mass="153850" checksum="EB06FF54CD2642D9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMK3</accession>
    <name>A0A1J1GMK3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Aurora kinase</fullName>
            <ecNumber evidence="12">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PGAL8A_00133800</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="12"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526455.1">
        <property type="nucleotide sequence ID" value="XM_028674866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMK3"/>
    <dbReference type="GeneID" id="39729863"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00133800"/>
    <dbReference type="OMA" id="KNRPCIK"/>
    <dbReference type="OrthoDB" id="345735at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14007">
        <property type="entry name" value="STKc_Aurora"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030616">
        <property type="entry name" value="Aur-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24350">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE IAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 8 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 11 14" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="32"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="159"/>
            <end position="160"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="cross-link" description="Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)" evidence="9">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU367134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG93633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="353" mass="40938" checksum="62452E6E0A6B4AE1" modified="2017-02-15" version="1">MNDSISSPIKATCRDMALKSSLHSFTFSLKDFDIAGFLGDGAHGSVFLACERRTNFICVLKCISKSHLVKSTQEALLRKEIELQAHLKHPHIACMYTWFHTSSHVFFVMEYCSNGDLFTYLNEHGPFSEKKVAEMLFEIIWAIRTCHDKRIAHLDLKPENVLVNHEEKCKLADFGLSAHIGSKHKKKGISHYRGTHDYWSPEQCARHQKKKQNFGEFDQKTDIWTLGILAFELKFGRPPFGSTNEERESIIMNRIQDYHWSQLFCEKVKKDLIDKLSPEFKDFLNLCLDKNPKKRPTAESLIQHPFIFIHNKNRPCIKAYATQPRGRQGPKLSHKGFNEQEGSFLTPIWFHNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMT3</accession>
    <name>A0A1J1GMT3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Parasitophorous vacuolar protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00128000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526395.1">
        <property type="nucleotide sequence ID" value="XM_028674800.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMT3"/>
    <dbReference type="GeneID" id="39729805"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00128000"/>
    <dbReference type="OrthoDB" id="391771at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013062993" description="Parasitophorous vacuolar protein 2" evidence="3">
        <location>
            <begin position="23"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="341"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="408"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="408"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="461" mass="53180" checksum="DF86FDE3F106B743" modified="2017-02-15" version="1">MKSVKHTVVLLLFLNFVLNILAKEYNIRTDKRKFFQGPRNSLINFLAKKKGYDTNGWIDISLLDGNFNSIDIKVHNDKVICNEGNKILEVSVEKQTLIQQTGSATYNEVLFSHIQLAQSSRFVNPLPVMKSNNYSNAVDPKIVLPANFEGYVVCEKKDSNALLIPKNFETVEFIAPPWSVRVSIDVFRNPISQYGRQFRVTIIDNVNILMNNQSSFIWPIPFESFSEVYDFHLAVRDSKEGRFCILERDLETFELNLSCSSWKRTYKLSLVNTYFLAGFLGMNTIQGISYPFLKSKKISYYEEPRGGDVFKILLDDESKNPDGTNVYVDNGYEQNRKARRWIGALSNIIYLGTVALTNAIYGTIKFINIRRNLDRFNREFEEAPLYYPWKLQYPEDYYTPNNVEVNETQKSESASVTDSEEKVDDSPVPEEIPEKEQTEDENLQNPTILKQVEQIIVDNDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN35</accession>
    <name>A0A1J1GN35_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00148600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526602.1">
        <property type="nucleotide sequence ID" value="XM_028675030.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN35"/>
    <dbReference type="GeneID" id="39730010"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00148600"/>
    <dbReference type="OMA" id="KYYYHKK"/>
    <dbReference type="OrthoDB" id="370114at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012362507" evidence="1">
        <location>
            <begin position="19"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="256" mass="31384" checksum="476645F32E638B9B" modified="2017-02-15" version="1">MKFYILNILYLLFLLVFCSENLMNEKIKKIVNEADECLPEDVEFMDNYTLKLYWIWTNNFFRYLRVKMYIYENDDIYRKIIKKHKNMLGAFKDNFIIYNNRSEFIKNALTILSSEKTLKKFIDLYVPIKKVKFFQELTETSLLNLLLKEKTNLINSYKKYLIFEEFRDVANSKYYYHKKLLENKWDSKIDDALLLDKKKKYNNDNDNINNKQIKNVITFNINEIPHLEESQFNYYDNKKWNKYLHYDLNNPRDLSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN87</accession>
    <name>A0A1J1GN87_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mitochondrial ribosomal protein L46, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00155400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526666.1">
        <property type="nucleotide sequence ID" value="XM_028675101.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN87"/>
    <dbReference type="GeneID" id="39730078"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00155400"/>
    <dbReference type="OMA" id="CTFEKRK"/>
    <dbReference type="OrthoDB" id="414075at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040008">
        <property type="entry name" value="Ribosomal_mL46"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13124">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L46, MITOCHONDRIAL PRECURSOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13124:SF12">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="351" mass="42565" checksum="57C1B3D62EB08D73" modified="2017-02-15" version="1">MIKKVVEKSILKNISQLNYMSLINKNFNKFFHHKDNTYYRKELKKKNILSDNRTISTNINISETKEIIVHDKYKVQVSLCIDRFPLNFVQEEFEKDFEKFKDEWLLRTNNNLEISEDFLHMKYNLSSFDEKKNSEKNILENSINYENKEKRKEDEDEDEYENESKEENEKKDETDDLEDLISLEGMQNIFKAKEKKKDDANIKEKKKNDIDINENDYKNIKRKPNNFLYLLVKYKKTNKWMFPLIDFKKNLTIRQNLKYLCSEHLKCEMPFFIGYCPCTFEKRKFKIPLLPNEIIGRKIFYYRAHYTNNEKNLDVAKNEYINDFAWLSRSELKNFLSKNKYHVIKDALPLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNI3</accession>
    <name>A0A1J1GNI3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">High mobility group protein B4, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">HMGB4</name>
        <name evidence="6" type="ORF">PGAL8A_00165700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526770.1">
        <property type="nucleotide sequence ID" value="XM_028675216.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNI3"/>
    <dbReference type="GeneID" id="39730183"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00165700"/>
    <dbReference type="OMA" id="FLEDCLY"/>
    <dbReference type="OrthoDB" id="498543at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001046">
        <property type="term" value="F:core promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000108">
        <property type="entry name" value="High mobility group protein B4, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050568">
        <property type="entry name" value="Transcr_DNA_Rep_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252:SF5">
        <property type="entry name" value="DR1-ASSOCIATED COREPRESSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252">
        <property type="entry name" value="HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09011">
        <property type="entry name" value="HMG_box_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="5">
        <location>
            <begin position="6"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="6"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="51"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="248" mass="29610" checksum="B98AC8DF252DC5A0" modified="2017-02-15" version="1">MDRKKPKVPPSSYLIFCNYERDNVKNILLEKSNKATIKITDIQKELSNKWKSLSEEERNKYEEQAQILKSKYNEELLEWQNLQKNDMSGVTNMQNFTKFPIMKIQKIMHLNNNVKKINNEAINIFQKAVIMFLIELVNKTIEYKNEKNSSRYITTLDIISCIKREGIKYKFLEDCLYLLKDEGINTFFLEDDENEESLFDLCEEDKKEYDYDIEEKKLSKLKKKENKAKDKNGKKNVYADITTFFKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNJ1</accession>
    <name>A0A1J1GNJ1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00155500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526667.1">
        <property type="nucleotide sequence ID" value="XM_028675102.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNJ1"/>
    <dbReference type="GeneID" id="39730079"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00155500"/>
    <dbReference type="OMA" id="AKNMILH"/>
    <dbReference type="OrthoDB" id="10067602at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="114" mass="13530" checksum="C546CAB316693367" modified="2017-02-15" version="1">MEKEIECQTEVVDDISKGIKISEKLNSILILYAKNMILHNPVRGYESENENIIKKRIYEWSKEYFRKLLDENEVNKNIKEDIKCDLISTHTDSNAIKDKIKKEIERVNFNIKND</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNK7</accession>
    <name>A0A1J1GNK7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosomal protein L1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00174900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526863.1">
        <property type="nucleotide sequence ID" value="XM_028670074.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNK7"/>
    <dbReference type="GeneID" id="39730276"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00174900"/>
    <dbReference type="OMA" id="LYCNFDL"/>
    <dbReference type="OrthoDB" id="10251727at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_uL1/biogenesis"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="Ribosomal protein L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="303" mass="36378" checksum="45741F085C59A1E2" modified="2017-02-15" version="1">MKGKNKKKEIFEKKKKENKKFLDFIKANQKYEKFQKAILNNKSQKINKKVHNIKLRNKTNLSVFKTYDIIEKSTFYKAYDFIVEKGLNDEIKNLFYDSYILYCNFDLSSSYNLGKYYNFSIDLTHSYYSDVILFVYENSEKWKKFILENKIKKIKKVMTFDKFESVYYKEDLLNEITNRYDLYIFDSCIRTKKYTHLISKIKKNNKTFTTLQLNEETFVENINKVIRKTYTDLNKGSTHSVPIGYLSIGKEKLYDNIKEVAKFMLPFYEQKKVSVVSINLRYINMTIPLYIHALKYETNSESN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNR9</accession>
    <name>A0A1J1GNR9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Pyrroline-5-carboxylate reductase</fullName>
            <ecNumber evidence="12">1.5.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PGAL8A_00164300</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-proline + NAD(+) = (S)-1-pyrroline-5-carboxylate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:14105"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17388"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="EC" id="1.5.1.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 12">
            <text>L-proline + NADP(+) = (S)-1-pyrroline-5-carboxylate + NADPH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:14109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17388"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="EC" id="1.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="12">Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the pyrroline-5-carboxylate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.2" evidence="12"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526755.1">
        <property type="nucleotide sequence ID" value="XM_028675199.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNR9"/>
    <dbReference type="GeneID" id="39730168"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00164300"/>
    <dbReference type="OMA" id="YYFIESL"/>
    <dbReference type="OrthoDB" id="10263291at2759"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00361"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004735">
        <property type="term" value="F:pyrroline-5-carboxylate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3730.10:FF:000001">
        <property type="entry name" value="Pyrroline-5-carboxylate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000190">
        <property type="entry name" value="Pyrroline-5-carboxylate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.10">
        <property type="entry name" value="ProC C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01925">
        <property type="entry name" value="P5C_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053790">
        <property type="entry name" value="P5CR-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029036">
        <property type="entry name" value="P5CR_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000304">
        <property type="entry name" value="Pyrroline-COOH_reductase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00112">
        <property type="entry name" value="proC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645">
        <property type="entry name" value="PYRROLINE-5-CARBOXYLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645:SF0">
        <property type="entry name" value="PYRROLINE-5-CARBOXYLATE REDUCTASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14748">
        <property type="entry name" value="P5CR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000193">
        <property type="entry name" value="Pyrrol-5-carb_rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00521">
        <property type="entry name" value="P5CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11 12" id="KW-0521">NADP</keyword>
    <keyword evidence="8 12 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 12" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyrroline-5-carboxylate reductase catalytic N-terminal" evidence="13">
        <location>
            <begin position="5"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="Pyrroline-5-carboxylate reductase dimerisation" evidence="14">
        <location>
            <begin position="155"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="9"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>NADPH</name>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="64"/>
            <end position="67"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00050547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00052690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000193-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF14748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG93934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="261" mass="28554" checksum="15BE98A8CC1D9330" modified="2017-02-15" version="1">MENIKLGFIGLGNMGSALANRIANTNVVKKENIYYYGPSKKDNTFKYLNSNKEIACKCDIIICAVKPDVAGSVLKDIKTNLSEKLLISICAGIKIERLEQIVGENIKIVRVMPNTPCLVGEGSSTFCVNKNVNDIDKKYVIDIFNSCGIIHEIKEKDMDIASSLIGACPAYVCLFIESLIDAGVKNGLSRELSKKLILKSIYGSVKLVEESNLPVQQLKDNVCSPGGITAEALFTLEKNQFKFAIIDAITSGCEKSKTLFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNV1</accession>
    <name>A0A1J1GNV1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-i protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00178900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000021">
        <property type="protein sequence ID" value="CRG94077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526898.1">
        <property type="nucleotide sequence ID" value="XM_028670114.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNV1"/>
    <dbReference type="GeneID" id="39730316"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00178900"/>
    <dbReference type="OMA" id="WEKIMLK"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="481" mass="58548" checksum="48D34C9825433AED" modified="2017-02-15" version="1">MDLNLSDAISINSNESLNEGDSTVGFAHRAIKDATVSIPENPLYADLNLRDAIQNPSEDINLDSATSINLLHKKSLSIFQLVIIIIFFLRFKRAFSPKLEAKHKERVKLQNKRDNRDKKMKGDWEKMEKKWNERKQKENREKERENDSEDKSLKILNSSCASGKKIESLNEKQYDIYLNEPCTRQACNKTVKKKEKNNMALDNKGEKSKGKSSNKLDSELELEKKRREELFRQVVELDEKWKKYEEHCIMMNEWEKEERKKLEEKRRERREKHEKELLIEYEERKRSMIEKNKEWEKIIQKEKKEWKKRILKEKEKMKECEKKMLKEKKEMEMWEKGVLTEKEVWEKRTLKEKQECDKSMLKQLEEWEKRILKKGEDWEKRMLIEKEKLEKKMLKNKEEGEKKMLKEKEEWEKIMLKEKEEWEKIMLKEKEKLEKSIMEKNEKWKTEENMKVNEEESELNLKRKKELDKIKAKEGKKIKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP04</accession>
    <name>A0A1J1GP04_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00389800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527015.1">
        <property type="nucleotide sequence ID" value="XM_028670243.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732428"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00389800"/>
    <dbReference type="OMA" id="HMARNEN"/>
    <dbReference type="OrthoDB" id="377390at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070382">
        <property type="term" value="C:exocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042043">
        <property type="term" value="F:neurexin family protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45716">
        <property type="entry name" value="BITESIZE, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45716:SF2">
        <property type="entry name" value="BITESIZE, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1432"/>
            <end position="1452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1513"/>
            <end position="1533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="227"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="703"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="784"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1749"/>
            <end position="1771"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1663"/>
            <end position="1690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="228"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="238"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="703"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="722"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="806"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1759"/>
            <end position="1769"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1943" mass="236226" checksum="46D5A3D0339EA831" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP46</accession>
    <name>A0A1J1GP46_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00178200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000021">
        <property type="protein sequence ID" value="CRG94070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526891.1">
        <property type="nucleotide sequence ID" value="XM_028670106.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP46"/>
    <dbReference type="GeneID" id="39730309"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00178200"/>
    <dbReference type="OrthoDB" id="6362699at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="316"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="349" mass="41235" checksum="244A8A0035B9AB9E" modified="2017-02-15" version="1">MAFLYNDGCVESEGDITKCSMNICQISQKKFQTSYCRIQPPVVHIKKSLNNNLNDLSKNLFTYEFTPANFHSRIIILSNNDKDGILLLYEYNPNHNQYPDKTYLCLLRNINQKLTLCEAVNIEYFGRSLTFDSYDFINEENKKINMISLRNPNHKIIKSKYDKFIFKEHYCHHIKTKYISHCTKRNTICKKINNDQLQCTDANYSGSLIKLDYVEYYVLKRKHIYLPSGCLKENLNPVCTPHICVSHAINEFYECEYEEISVIKNIRPINNIRPINNIRPINKLRSIHIIEPNSKNLPVMSLKHKDISHKNSFDNAALFAMSFMSFLVIFIFFFCLLYRTFRKKRRKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP91</accession>
    <name>A0A1J1GP91_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00401500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527132.1">
        <property type="nucleotide sequence ID" value="XM_028670373.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP91"/>
    <dbReference type="GeneID" id="39732545"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00401500"/>
    <dbReference type="OMA" id="IHHNELK"/>
    <dbReference type="OrthoDB" id="377540at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1054" mass="126871" checksum="E6967459CEADF1E0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPM9</accession>
    <name>A0A1J1GPM9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S26</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPS26</name>
        <name evidence="5" type="ORF">PGAL8A_00408500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527202.1">
        <property type="nucleotide sequence ID" value="XM_028670451.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPM9"/>
    <dbReference type="GeneID" id="39732615"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00408500"/>
    <dbReference type="OMA" id="KCYCVSC"/>
    <dbReference type="OrthoDB" id="10262653at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1740.20:FF:000003">
        <property type="entry name" value="40S ribosomal protein S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1740.20">
        <property type="entry name" value="Ribosomal protein S26e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000892">
        <property type="entry name" value="Ribosomal_eS26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047864">
        <property type="entry name" value="Ribosomal_eS26_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038551">
        <property type="entry name" value="Ribosomal_eS26_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12538">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12538:SF0">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01283">
        <property type="entry name" value="Ribosomal_S26e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00733">
        <property type="entry name" value="RIBOSOMAL_S26E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="107" mass="12493" checksum="51E21F72D715696D" modified="2017-02-15" version="1">MPKKRRNGGRSKHNRGHVNPLRCSNCGRCVPKDKAIKRFNIRNIVDASAQRDIKEASVYSTFQLPKLYIKQCYCVSCAIHSRFVRVRSREQRRVRKETAKHINPSQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPN7</accession>
    <name>A0A1J1GPN7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fam-a protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00096100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526077.1">
        <property type="nucleotide sequence ID" value="XM_028672211.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPN7"/>
    <dbReference type="GeneID" id="39729485"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00096100"/>
    <dbReference type="OMA" id="GVWKFYF"/>
    <dbReference type="OrthoDB" id="381924at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013017913" description="Fam-a protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="382" mass="45382" checksum="5635AEAAC14F82E3" modified="2017-02-15" version="1">MIRLILLLTILCELILWNFKKINSFRLNANHSNKITKDCNVIYDATKRKKFIFKKYEIKRNFKDKLYLSHFNETNNNKREITEDHIEEQLKNVVKDIQGVWKFYLPIYIMDTEFEKPKDEELDKNYKLDNSDDFQINDDTNEENSDDNNLNILRGERLHPLPLFVYNYEQIYSASNSTYACWSNHYISKNIYECTIKIVNKMNNKYMIILQGYLFISQINAIKDNNIRLRPCQIFGNIFLAHNDTVEEKSIIPSNVKIYDKSGNEVKDIISILEKKIPEFRKDKKKIEAFLGLKKWKFLGISTAYKILGEGKNIFNINHILTGKDENTFYNVMDFDSINNNYEKNCFIYLKDIFNSYFEKPSSDIFSLIMKNMQEKSINGPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPS2</accession>
    <name>A0A1J1GPS2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Plasmodium RESA N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00400400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527121.1">
        <property type="nucleotide sequence ID" value="XM_028670361.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPS2"/>
    <dbReference type="GeneID" id="39732534"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00400400"/>
    <dbReference type="OMA" id="IHHEMIK"/>
    <dbReference type="OrthoDB" id="374751at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="277" mass="32688" checksum="A5594BD30C8DC696" modified="2017-02-15" version="1">MLKRCAYFFFVIIIVLDKYGLILSSSNNKKENNELYLTRTKESYNFLEASLNIINNKGPSYNSVLNKLSNVDLPNVHHEVIKNLKFDKLKEIVNIKNSILNCILESVLHMVKALPAIIEEILEYNEFCSSIETQFSFLYAVDNEYQEKIEDCRTSTTDSIINSYFSFYLEDIDLIVKKYKEKPGDIFNRFDSIVECLDEFYKKVTRPFNEHVKETELFKDFMTKYIKPPGSTYVDYLKAFLDNFDSNWSNEKITGFFDELYYIYSTNNSYISCFYLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ01</accession>
    <name>A0A1J1GQ01_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00191700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000028">
        <property type="protein sequence ID" value="CRG94519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527335.1">
        <property type="nucleotide sequence ID" value="XM_028670598.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730442"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00191700"/>
    <dbReference type="OrthoDB" id="348930at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="323"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="468"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="503"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="528"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="556"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="580"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="681"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="716"/>
            <end position="729"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1894" mass="222269" checksum="C8796292919AAEB3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQD2</accession>
    <name>A0A1J1GQD2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein transport protein SEC7, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SEC7</name>
        <name evidence="4" type="ORF">PGAL8A_00202100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527439.1">
        <property type="nucleotide sequence ID" value="XM_028670714.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730547"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00202100"/>
    <dbReference type="OMA" id="GEYISHR"/>
    <dbReference type="OrthoDB" id="18431at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032012">
        <property type="term" value="P:regulation of ARF protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1000.11">
        <property type="entry name" value="Arf Nucleotide-binding Site Opener,domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023394">
        <property type="entry name" value="Sec7_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000904">
        <property type="entry name" value="Sec7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035999">
        <property type="entry name" value="Sec7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF388">
        <property type="entry name" value="GOLGI-SPECIFIC BREFELDIN A-RESISTANCE GUANINE NUCLEOTIDE EXCHANGE FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00222">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48425">
        <property type="entry name" value="Sec7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50190">
        <property type="entry name" value="SEC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2339"/>
            <end position="2357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2409"/>
            <end position="2428"/>
        </location>
    </feature>
    <feature type="domain" description="SEC7" evidence="3">
        <location>
            <begin position="961"/>
            <end position="1296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="659"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="817"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="931"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="968"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1546"/>
            <end position="1590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2830"/>
            <end position="2920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="831"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="978"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="993"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1564"/>
            <end position="1590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2841"/>
            <end position="2920"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2920" mass="348701" checksum="D760277C2A56E291" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR50</accession>
    <name>A0A1J1GR50_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Syntaxin, Qa-SNARE family, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00239000</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527806.1">
        <property type="nucleotide sequence ID" value="XM_028671123.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR50"/>
    <dbReference type="GeneID" id="39730918"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00239000"/>
    <dbReference type="OMA" id="HNLSSYH"/>
    <dbReference type="OrthoDB" id="370804at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15959">
        <property type="entry name" value="SYNTAXIN-18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15959:SF0">
        <property type="entry name" value="SYNTAXIN-18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="371"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG94993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="390" mass="47479" checksum="A8496EE10D1DB79B" modified="2017-02-15" version="1">MDRFDEFIHLCKKFDKNVDFVKREKKEKDFFLIKSSEIYTKLFSNCEYIDNKTLKKYGLFLKNKYIKEHKTKIKNKDHLIYSIKKISENIKFLKPQIEIHKHILNCLNNLLSIFIDIINKYEHNLNNYLFKLNKYTNFYFYDIQSIKFNFDYLNKLNNIIYSDFYNNQPNEFNIDSSFECSSFMKNKKHNDCGNNKRVNLKNEDNNDDEKTLLNNENYVNDKSTKLNEIYNGDNSNKNLRKRESNKIKFERKDNNDIYNKYNYIEEEEEKKNDWMHNNSVFHDDYPLNNNQKLEFKKYVDLFEKEENTYIMETKKKVAKISNLMNVFVNKIYEQNENLKMIENIIEESIENVSHGNIYLSKIQKKKNLNSLIFFVLICASFFLFIFDFFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR58</accession>
    <name>A0A1J1GR58_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00217500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527593.1">
        <property type="nucleotide sequence ID" value="XM_028670885.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR58"/>
    <dbReference type="GeneID" id="39730702"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00217500"/>
    <dbReference type="OrthoDB" id="374050at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="110" mass="13243" checksum="E973DB2484CE5DD6" modified="2017-02-15" version="1">MKKINLLLNGLGNIFKKRNNNQLQSSILKNIKIQNIYCNEKINKKDHYIYFKEYDIKTNNCDYKKVMKTKKLFKVGNYNKNVILFICFGSISSIILFVFFISVKWNNYYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRF4</accession>
    <name>A0A1J1GRF4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00248900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527902.1">
        <property type="nucleotide sequence ID" value="XM_028671229.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRF4"/>
    <dbReference type="GeneID" id="39731017"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00248900"/>
    <dbReference type="OMA" id="AECPECI"/>
    <dbReference type="OrthoDB" id="371995at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="256" mass="29994" checksum="92CF3FCCB141419F" modified="2017-02-15" version="1">MNNYSENDSDSTVEETLVMLNFPQLNNDENKLKNLNIFRKKKSEHPEKIPNSNNLPNQYTINDINGIEIDLTKDNNNNTEETLNNDIILNKNDNNVNCNSYDIQENNKQCNNREVQYKMNENVINSDSYMVNETNKELVDNDKCTLKKSESCLDNNIIDNIPFEVNSITLKNIFTENPQCVINDKYKFKGIQTSSIGTNLYFKEPESLKNKNDLKNYEISYDDYNRNIKNENKMTRDDFTIYEGYSTKIISFKIDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRM7</accession>
    <name>A0A1J1GRM7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ubiquitin conjugating enzyme, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00256600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527974.1">
        <property type="nucleotide sequence ID" value="XM_028671308.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRM7"/>
    <dbReference type="GeneID" id="39731094"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00256600"/>
    <dbReference type="OrthoDB" id="1158011at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23808">
        <property type="entry name" value="UBCc_UBE2W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000076">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBC core" evidence="1">
        <location>
            <begin position="122"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="266" mass="30883" checksum="A39E4B99652D156A" modified="2017-02-15" version="1">MKKTRVLEILTIFYIFIFIKNGNKIFIRSNSFSKIHRYKYLMGYGNKYSNFMIKTSCSTKDKVNTHENPLNYHKKKKYILKENKNVTRHLFTIQPDKTFSSGGLKPSKSVLKHIKKKYKLGNSNYRIQKELNNFLKNPPINCTIDVHPNNIRVWIVQYVGLENTIYANEVYKIKIIFSDDYPLKPPTVYFLQKPPKHTHVYSNGDICLSLLGDDYNPSLSISGLILSIISMLSSAKEKKLPIDNYTHADAKPGSSQNNFLYHDDKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRX1</accession>
    <name>A0A1J1GRX1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00001400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528060.1">
        <property type="nucleotide sequence ID" value="XM_028671404.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRX1"/>
    <dbReference type="GeneID" id="39728536"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00001400"/>
    <dbReference type="OMA" id="PMERQIN"/>
    <dbReference type="OrthoDB" id="10668236at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="442"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="487"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="106"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="152"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="487"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="512"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="532"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="550"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="587"/>
            <end position="597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="597" mass="67436" checksum="549B78CECBDF1D92" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSE9</accession>
    <name>A0A1J1GSE9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Repetitive organellar protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ROPE</name>
        <name evidence="3" type="ORF">PGAL8A_00021300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528254.1">
        <property type="nucleotide sequence ID" value="XM_028671619.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728735"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00021300"/>
    <dbReference type="OMA" id="KHMFIPE"/>
    <dbReference type="OrthoDB" id="2378640at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="51"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="314"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="700"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="859"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1098"/>
            <end position="1211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1625" mass="195405" checksum="C7D5696AC226E97C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSH2</accession>
    <name>A0A1J1GSH2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Inner membrane complex protein 1f, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00262800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528035.1">
        <property type="nucleotide sequence ID" value="XM_028671376.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSH2"/>
    <dbReference type="GeneID" id="39731157"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00262800"/>
    <dbReference type="OMA" id="VVHKVNK"/>
    <dbReference type="OrthoDB" id="365616at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022086">
        <property type="entry name" value="IMCp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12314">
        <property type="entry name" value="IMCp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1078" mass="123994" checksum="56AB2D9E6DBAE38D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSI6</accession>
    <name>A0A1J1GSI6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PIR-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00268700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000038">
        <property type="protein sequence ID" value="CRG95485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528294.1">
        <property type="nucleotide sequence ID" value="XM_028671664.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSI6"/>
    <dbReference type="GeneID" id="39731217"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00268700"/>
    <dbReference type="OMA" id="RIANDSW"/>
    <dbReference type="OrthoDB" id="394175at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="402" mass="46015" checksum="E164D8AB9AC4224F" modified="2017-02-15" version="1">MKTHHHSMMILCLFILVWIFQYFCYMSFEIKENNLKKVSQLRIGRLLAEAQSCLLTTETRYLCRSGENLTTWLESLQGDLLTQIEKNQNNFTCNNTDSLINWMSNKTMEMAFSLNRNSDIKDKGILNNAWSVWKYLKDIVNDYFSYILDNFSCKITRENINNITDWMYNRSRLVIKDLNLNSDIGKKKFLNDTLSVWRQMTNAITNFTMESFTNYTMSTDQTKNSSDLLTTPVLPTTSDSLSTSSSLITGTLSNISSNISLNASIDEIETTPIGKVITKILGDISTLPPRTEISTNDACSEFLCGSTASISISVPLVVIGGVLFLTLLYKYTRIGSLLGRGNLQKEKGRKRLRETSLDNIEDPSESSMEKEEMKPKRSRLNSFLRAFGHKYRNIFPYIDENR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSK3</accession>
    <name>A0A1J1GSK3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00173400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526848.1">
        <property type="nucleotide sequence ID" value="XM_028670058.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSK3"/>
    <dbReference type="GeneID" id="39730261"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00173400"/>
    <dbReference type="OMA" id="SAWKKKD"/>
    <dbReference type="OrthoDB" id="378901at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="80"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="179"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="113"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="637" mass="74721" checksum="5834DB461034913C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSK7</accession>
    <name>A0A1J1GSK7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">inorganic diphosphatase</fullName>
            <ecNumber evidence="3">3.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00400000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.1" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527117.1">
        <property type="nucleotide sequence ID" value="XM_028670357.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSK7"/>
    <dbReference type="GeneID" id="39732530"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00400000"/>
    <dbReference type="OMA" id="VNLNFHN"/>
    <dbReference type="OrthoDB" id="1608002at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006796">
        <property type="term" value="P:phosphate-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.80.10:FF:000010">
        <property type="entry name" value="Probable inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.80.10">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008162">
        <property type="entry name" value="Pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036649">
        <property type="entry name" value="Pyrophosphatase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10286">
        <property type="entry name" value="INORGANIC PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00719">
        <property type="entry name" value="Pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50324">
        <property type="entry name" value="Inorganic pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00387">
        <property type="entry name" value="PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG94296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="367" mass="43810" checksum="12FF6612CD97BCF4" modified="2017-02-15" version="1">MKKMIINSDNNKVLNKDHKDDYHLETNNELKVNLNFHNNNIISNIFSNLSLFEKINNIFTIEGKTYMLKYCNNLNEDDFNISYYQKVDKNFIPISPWHNLNLMNEDGTYNMVVEITKYNYIKLEIKLTEKYNVIKQDKKKGKLRYYHNSIYWNYGALPQTYEYPKHIYNYRAKDNQQIFFTGDDDPLDIVDIGQNSLKMGQVVPVKILGAFTLIDEGQLDWKIIGINKYDKNFNNISNLDDVETYYPHTMNLLLEWFRSYKMAESKKLNIICKELYNKKESEDLIKKTHEYYLEFLKDVKLLNSNKKDTNVYKHSHNDNINTNEYNHNDFLNKIHDDSIYNKLLQNIHVSYCKANPSYRPNGNIWIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSN0</accession>
    <name>A0A1J1GSN0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00269900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000039">
        <property type="protein sequence ID" value="CRG95499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528308.1">
        <property type="nucleotide sequence ID" value="XM_028671680.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSN0"/>
    <dbReference type="GeneID" id="39731231"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00269900"/>
    <dbReference type="OrthoDB" id="6362699at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="317"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="340" mass="40185" checksum="A7BC60C96CBE22FB" modified="2017-02-15" version="1">MAFLYNDGCETSEGDFTKCFMNICEINLNKFEASYCRIERPVVDIKKASNKNLNDLSKNLFTDEYTPSNLKSRIIILSNNDKDGILLLYEYNPHQHQYPDKTYLCRLRNINQKLTLCEAVNVEYFGRSLTFKSYDIINEENEKNNMISLKNPNHKIIISKYDELIFKEHYCHPMKTKYISHCNKRYTICKKINNDQLHCSDANYSGHLIRLDYNEYNVLKRNYIYLPSSCLKENLNPVCTPHICVSHAYNEFFQCKHEEISIIKNIRPINNIRPINNIRPINKLRSIHIIEPNSKNLPVMPLKHKDISHKNSFDNTALFAMSFMPFLVLFIFFFCLLYKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSR4</accession>
    <name>A0A1J1GSR4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">N-acetyltransferase, putative</fullName>
            <ecNumber evidence="5">2.3.1.88</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00379500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the acetyltransferase family. ARD1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.88" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526912.1">
        <property type="nucleotide sequence ID" value="XM_028670129.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSR4"/>
    <dbReference type="GeneID" id="39732325"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00379500"/>
    <dbReference type="OMA" id="LPENYFM"/>
    <dbReference type="OrthoDB" id="25586at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031415">
        <property type="term" value="C:NatA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990189">
        <property type="term" value="F:protein N-terminal-serine acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990190">
        <property type="term" value="F:protein-N-terminal-glutamate acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045047">
        <property type="entry name" value="Ard1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23091">
        <property type="entry name" value="N-TERMINAL ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23091:SF4">
        <property type="entry name" value="N-TERMINAL AMINO-ACID N(ALPHA)-ACETYLTRANSFERASE NATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="4">
        <location>
            <begin position="2"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="152" mass="17827" checksum="E88FC52AC31A1EAF" modified="2017-02-15" version="1">MLSIRKCNVYDLLSMQECNSINLPENYNLRYYFYHALSWPYLSHIAEDGKGKVCGYSLGKLEEDNEKKGHLTSVAVLKNYRKLKLAFYLISQTHQHLKDIYLANNICLHVRVSNNAALNLYYNLLNYKVKGIEPMYYGNKENAYLMEHIFSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSX6</accession>
    <name>A0A1J1GSX6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PPR repeat protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PPR</name>
        <name evidence="3" type="ORF">PGAL8A_00278300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528394.1">
        <property type="nucleotide sequence ID" value="XM_028671775.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSX6"/>
    <dbReference type="GeneID" id="39731316"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00278300"/>
    <dbReference type="OMA" id="VIFACNM"/>
    <dbReference type="OrthoDB" id="440666at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF17">
        <property type="entry name" value="OS12G0638900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="123"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="393"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="555" mass="65237" checksum="5A2AD436DA888B3D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSY4</accession>
    <name>A0A1J1GSY4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">AAA family ATPase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00284300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528454.1">
        <property type="nucleotide sequence ID" value="XM_028671841.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSY4"/>
    <dbReference type="GeneID" id="39731376"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00284300"/>
    <dbReference type="OrthoDB" id="378265at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001474">
        <property type="entry name" value="Putative AAA family ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF27">
        <property type="entry name" value="ATPASE FAMILY GENE 2 PROTEIN HOMOLOG A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="331"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="724"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="236"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="240"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1120" mass="131769" checksum="1C23C6B05F319BA9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT19</accession>
    <name>A0A1J1GT19_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00282300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528434.1">
        <property type="nucleotide sequence ID" value="XM_028671819.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT19"/>
    <dbReference type="GeneID" id="39731356"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00282300"/>
    <dbReference type="OrthoDB" id="370508at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012227311" evidence="1">
        <location>
            <begin position="20"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="332" mass="39584" checksum="E321A5B193250B28" modified="2017-02-15" version="1">MSMIFYVSSIFFLLNTISCINLQIGNQKYQLSTNKIKSDLLDFYSTLNILKSEKYLKDSIKKINLYTKLRKRLYKDRLSIYANISVKEKEDVPIKVTEGTEKKVENEKRDIIDQAFINNFMLFNKSNFFCIDELGIDINVPLLKNSNFGANIVYQLPKVIYVNAYANAYNSIIKGEFNTIDIVKRISFFQFFENFYINANYDFKNKKALLNLESKFYEYYNKFGDNFSFNNKIILQRDSKNQYDGSVCLSLKYNNNVFTPIFNFKDKSYEYSYDNLNANRKFSVKIDKDRNVHFNYLSFDRVNDYNKYFLFFNFIFSNPMQSIITLKREFIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT29</accession>
    <name>A0A1J1GT29_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00288300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528494.1">
        <property type="nucleotide sequence ID" value="XM_028671886.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT29"/>
    <dbReference type="GeneID" id="39731416"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00288300"/>
    <dbReference type="OrthoDB" id="376983at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="78"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="137" mass="16663" checksum="A4B80997B7CC0A19" modified="2017-02-15" version="1">MKILKNMFFFNFLVVLLQIYYVLSDRKKKEEMNILNFLPSNSLLYPLDFQKNWQASEPIPVSVHYTVPAYGYKDLIEALEYHNDLENHLKEREEIERRIISEQKRLEDNLWNKVQFLKTKDMMLKKKNSLRTYKSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT38</accession>
    <name>A0A1J1GT38_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00280400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528415.1">
        <property type="nucleotide sequence ID" value="XM_028671798.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT38"/>
    <dbReference type="GeneID" id="39731337"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00280400"/>
    <dbReference type="OMA" id="NTYMENE"/>
    <dbReference type="OrthoDB" id="372196at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="37"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="299" mass="35164" checksum="CA878C4F0CF6AE61" modified="2017-02-15" version="1">MNKYMSSSSTILNNKKNVEYFMKNNLDVDKSIDDIKNKKYEEIYSEIKKKLIKLENTFLDKVLLQVKKKSVASKNNSVEKLAINELNKYKKNIELLKSKVSVEDNTDKIVKLENKLKENEEILQKLNNDKEGLENISKQQLKALDEICLNETQLSIQTKYEEISQLKEDLINLKNKYNENENILKKKQEQLINLDNQLKKKILSIKNAKNNNSNISTLNNNKNMSNNQIQTLKTQIDMINSHISNDELIYEDKIYELEKSIKSSENDIEFLNSQIEEIKKNNENISLDIKKMRRQKKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT50</accession>
    <name>A0A1J1GT50_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00393100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527048.1">
        <property type="nucleotide sequence ID" value="XM_028670280.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT50"/>
    <dbReference type="GeneID" id="39732461"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00393100"/>
    <dbReference type="OrthoDB" id="370861at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="371" mass="44282" checksum="723213330826A207" modified="2017-02-15" version="1">MYLKKNIFYFYKKNKFAFYLGSTWFLLINSSLLFSLKYYKNFESRHPYIFDAINILKLYLDFSNKDCLKLLKKKGNIDSSNKRAKCELLFSFNNEKIYLNINAINIKKKKDSNSYDDENKDISLYLENPFLIKKEIKNCIAKIKSFLFSFIASDDNEKNNLKNEDRIFNENRDLANKKEEIHNIIRNGSTWKIDNIILVKKKIDQNDERSKLFFINNFFNNFFNYSYQIDAIYGNPIDNSYFYKYDNKKKTFNNTQKNLMKVMLFAFFFSSILAIKRIFIYKNSYSSLNFVKHFVCNNKNLHNILGNNQIHILSISGIHEKNYLNSKIFFQAKEKQGVIQMTATRNGVDKHFSLLHAKLLYNYEIIELKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT72</accession>
    <name>A0A1J1GT72_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Glycylpeptide N-tetradecanoyltransferase</fullName>
            <ecNumber evidence="2 8">2.3.1.97</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00284400</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins. Myristoylates adenylate kinase AK2. During the asexual blood stage, may myristoylate proteins such as ARO, CDPK1 and GAP45. Probably by mediating protein myristoylation, plays a role in the assembly of the inner membrane complex during the early stages of schizogony and in the formation of rhoptries in the late stages and thus merozoite egress.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 8">
            <text>N-terminal glycyl-[protein] + tetradecanoyl-CoA = N-tetradecanoylglycyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15521"/>
            <dbReference type="Rhea" id="RHEA-COMP:12666"/>
            <dbReference type="Rhea" id="RHEA-COMP:12667"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57385"/>
            <dbReference type="ChEBI" id="CHEBI:64723"/>
            <dbReference type="ChEBI" id="CHEBI:133050"/>
            <dbReference type="EC" id="2.3.1.97"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterodimer composed of NMT and AK2; AK2 myristoylation stabilizes the complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the NMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.97" evidence="2 8"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528455.1">
        <property type="nucleotide sequence ID" value="XM_028671842.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT72"/>
    <dbReference type="GeneID" id="39731377"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00284400"/>
    <dbReference type="OMA" id="CPAMESE"/>
    <dbReference type="OrthoDB" id="60315at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004379">
        <property type="term" value="F:glycylpeptide N-tetradecanoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.170:FF:000001">
        <property type="entry name" value="Glycylpeptide N-tetradecanoyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000903">
        <property type="entry name" value="NMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022677">
        <property type="entry name" value="NMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022678">
        <property type="entry name" value="NMT_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022676">
        <property type="entry name" value="NMT_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11377:SF5">
        <property type="entry name" value="GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11377">
        <property type="entry name" value="N-MYRISTOYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01233">
        <property type="entry name" value="NMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02799">
        <property type="entry name" value="NMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015892">
        <property type="entry name" value="N-myristl_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00975">
        <property type="entry name" value="NMT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00976">
        <property type="entry name" value="NMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycylpeptide N-tetradecanoyltransferase N-terminal" evidence="10">
        <location>
            <begin position="57"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Glycylpeptide N-tetradecanoyltransferase C-terminal" evidence="11">
        <location>
            <begin position="226"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00059499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00062182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG95647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="413" mass="48339" checksum="933DCB33C4E84E97" modified="2017-02-15" version="1">MNDDNKNQKELAGNDIYELIKKAKDKIKNDYKFWYTQPVPKINDEFNETVNEPFIANNKVEDVRKEEYKLPNGYSWYVCDIKNENDRSEIFKLLSDNYVEDDDNIFRFNYSSEFLLWALSSPNYLKNWHIGVKYDAANKLIGFISAIPIDICINKKIVKMAEVNFLCVHKNLRSKRLAPVLIKEITRRINLENIWQAIYTAGIYLPKPLSDARYFHRSINVKKLIEIGFSSLNSRLTMSRAIKLFRIDDTLNLKNLRKMKKKDIDGLHNLLNNYLEQFKLHAVFSKEDIAHWFLPIDNVIYTYVNEENGEIKDLISFYSLPSQILGNEKYNILNAAYSFYNIATTTSIKNLMQDAIYLAKKNSFDVFNALEIMHNKSIFEDLKFGEGDGSLKYYLYNWKCASFDPSNVGIVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT82</accession>
    <name>A0A1J1GT82_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00289500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528506.1">
        <property type="nucleotide sequence ID" value="XM_028671900.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT82"/>
    <dbReference type="GeneID" id="39731428"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00289500"/>
    <dbReference type="OMA" id="FLLFREC"/>
    <dbReference type="OrthoDB" id="408698at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="144" mass="16804" checksum="1CC5BF0568EC317E" modified="2017-02-15" version="1">MNEKCDEIKLKYYTCLNNSKRNPKKCKIIEDELRGCSKKTGESYCIDEINNLMNCSRSPDPSSCAKEFVLFRECNRPDGPHIVIEDNKYVITKEHLDKYNVNDSIIGSVEAPERNNSNTISFLEKMKATLHLKNFKEKFVPYKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT85</accession>
    <name>A0A1J1GT85_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">14-3-3 protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00294700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 14-3-3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528550.1">
        <property type="nucleotide sequence ID" value="XM_028671948.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT85"/>
    <dbReference type="GeneID" id="39731480"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00294700"/>
    <dbReference type="OrthoDB" id="375811at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.190.20">
        <property type="entry name" value="14-3-3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000308">
        <property type="entry name" value="14-3-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036815">
        <property type="entry name" value="14-3-3_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023410">
        <property type="entry name" value="14-3-3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18860">
        <property type="entry name" value="14-3-3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00244">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00305">
        <property type="entry name" value="1433ZETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48445">
        <property type="entry name" value="14-3-3 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="14-3-3" evidence="4">
        <location>
            <begin position="345"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="50"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="235"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="78"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="122"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="527" mass="62293" checksum="06D6D9C770203935" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTE9</accession>
    <name>A0A1J1GTE9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Plasmepsin IX, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00301800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528614.1">
        <property type="nucleotide sequence ID" value="XM_028672019.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTE9"/>
    <dbReference type="GeneID" id="39731551"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00301800"/>
    <dbReference type="OMA" id="HQKFCCD"/>
    <dbReference type="OrthoDB" id="771136at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000115">
        <property type="entry name" value="Lysosomal aspartic protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase A1" evidence="7">
        <location>
            <begin position="229"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="485"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="260"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="617" mass="71870" checksum="434E041CA36A5C10" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTS2</accession>
    <name>A0A1J1GTS2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF8019 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00183500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527264.1">
        <property type="nucleotide sequence ID" value="XM_028670519.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTS2"/>
    <dbReference type="GeneID" id="39730362"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00183500"/>
    <dbReference type="OMA" id="NNHMHKL"/>
    <dbReference type="OrthoDB" id="9987655at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058332">
        <property type="entry name" value="DUF8019"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42535:SF2">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_146, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42535">
        <property type="entry name" value="OOKINETE PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26058">
        <property type="entry name" value="DUF8019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13385">
        <property type="entry name" value="Laminin_G_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012000752" description="DUF8019 domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="DUF8019" evidence="2">
        <location>
            <begin position="273"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="354" mass="40277" checksum="6172AC6AADB6DE3D" modified="2017-02-15" version="1">MVIFILFFFIYNIKLAKLEKSLFNYLSEISFSEPFENLFEKCLEIPNNICLGGTTTPIISHSIHNGLIGKWTFDDIYALDYSSNKNHMHKLIRNGPSFNGHGYSGAFIGDISGFVPSGETLKTTQFTIVFWIYLLERSTSHFRNIISQIDNKEEKIAILLHPHTTKISVRIMGKDNSNEGLSSIGHIPLRRWTNIAITLNEKQVEIYVNGVFDNSVFLKSKIVEKRGNITIGKNSNYSSFNGYLDELHFYNRSLNVSEIKSFSIPSITGIYDTNFVHIGCLSCDYDTAKSDNLCKKNYELCSLFNLYNGGIHYARINGILTEKSNIWASDISEDTIEKGEKRIALCCKLYKDNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTU0</accession>
    <name>A0A1J1GTU0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">YTH domain-containing protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00291700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528521.1">
        <property type="nucleotide sequence ID" value="XM_028671916.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTU0"/>
    <dbReference type="GeneID" id="39731450"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00291700"/>
    <dbReference type="OMA" id="RINHNNC"/>
    <dbReference type="OrthoDB" id="1914176at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990247">
        <property type="term" value="F:N6-methyladenosine-containing RNA reader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048024">
        <property type="term" value="P:regulation of mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21134">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.590.10">
        <property type="entry name" value="ph1033 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007275">
        <property type="entry name" value="YTH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045168">
        <property type="entry name" value="YTH_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12357:SF3">
        <property type="entry name" value="YTH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12357">
        <property type="entry name" value="YTH YT521-B HOMOLOGY DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04146">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50882">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="3">
        <location>
            <begin position="71"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="3">
        <location>
            <begin position="99"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="3">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="YTH" evidence="4">
        <location>
            <begin position="438"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="71"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="99"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="246"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="255"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="639" mass="74933" checksum="7096E7D152B0EA25" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTY7</accession>
    <name>A0A1J1GTY7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GPN-loop GTPase 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">XPA-binding protein 1 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PGAL8A_00320300</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GPN-loop GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528798.1">
        <property type="nucleotide sequence ID" value="XM_028672225.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTY7"/>
    <dbReference type="GeneID" id="39731736"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00320300"/>
    <dbReference type="OrthoDB" id="243313at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17870">
        <property type="entry name" value="GPN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000888">
        <property type="entry name" value="GPN-loop GTPase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004130">
        <property type="entry name" value="Gpn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030230">
        <property type="entry name" value="Gpn1/Npa3/XAB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231:SF8">
        <property type="entry name" value="GPN-LOOP GTPASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231">
        <property type="entry name" value="XPA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03029">
        <property type="entry name" value="ATP_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="80"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="88"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00055682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00083137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG95990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="492" mass="57552" checksum="715AC5B3899456CC" modified="2017-02-15" version="1">MKGKKEKITEEDIDKELNNIDNYKIDNNIKVPYILKKELKIENNNCIRKENYNNTNVNKFYNEEIFSEKREIYTPDSEVSESITTENVSKEKESEVNNLNEKKSEVNNLNEKESEVNNLNEKESEVNNLNEKESEVNNLNEKKSEVKLNEKKSEVNNLNEKESEINNMNEKEKDVNDLSEKEKENEDPKIKGNLKDYYQNLPTVIIVIGMAGSGKTTYVGSLYKYLKIEKKKKVYTINLDPAVKYLQYPTNIDIRDSIKYHEIMKEYKLGPNGAIMTCLNLFATRFDKVIEILEKRKQKLNYIIVDTPGQIEVFNWSASGNIILETLSVSFPVVINYVIDTVRCERPITFMSNMLYACSVLYKSRLPFLACFNKIDIIKHDKCIEWMKNYDSFNEDVLNDESYMASFSRSCALMINEFYEGIKTVGISSKTNEGFNNILKNLEYLKEEYISDYVPCIEKQMKRIKKKKEKDIKLKMESLLMEKQKNIPISKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU55</accession>
    <name>A0A1J1GU55_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Trailer hitch homolog, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CITH</name>
        <name evidence="7" type="ORF">PGAL8A_00196400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527384.1">
        <property type="nucleotide sequence ID" value="XM_028670653.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU55"/>
    <dbReference type="GeneID" id="39730491"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00196400"/>
    <dbReference type="OMA" id="NRNNKMM"/>
    <dbReference type="OrthoDB" id="21539at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033962">
        <property type="term" value="P:P-body assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034063">
        <property type="term" value="P:stress granule assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01736">
        <property type="entry name" value="LSm14_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025762">
        <property type="entry name" value="DFDF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019050">
        <property type="entry name" value="FDF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025761">
        <property type="entry name" value="FFD_box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025609">
        <property type="entry name" value="Lsm14-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025768">
        <property type="entry name" value="TFG_box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13586">
        <property type="entry name" value="SCD6 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13586:SF0">
        <property type="entry name" value="TRAILER HITCH, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12701">
        <property type="entry name" value="LSM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01199">
        <property type="entry name" value="FDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01271">
        <property type="entry name" value="LSM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51512">
        <property type="entry name" value="DFDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51513">
        <property type="entry name" value="FFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51536">
        <property type="entry name" value="TFG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sm" evidence="6">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="DFDF" evidence="3">
        <location>
            <begin position="186"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="FFD box profile" evidence="4">
        <location>
            <begin position="230"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="TFG box profile" evidence="5">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="FFD box" evidence="1">
        <location>
            <begin position="230"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="TFG box" evidence="2">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG94569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="321" mass="37465" checksum="D7AF003FEDE86AA2" modified="2017-02-15" version="1">MSSVSTLPYIGSKISLISNSEIRYEGILYTINTHESTVALQNVRSFGTEGRRQPDIPPSNEIYDFIIFRGKDIKDVTVSEPAKNIPDDPAIVSMNIAPSSKNNLTENLNYNNNVNINKSLKVPSNIIPSNERNLNLNNRRFYNRNHYNFYYNNNNNNNRNFNNFKFKNFRSYERTPYVIGELESQPNPALKSKFSPDFDFSTNNLKFDKNNILDEKNKDSISLNNNLQVGGYDKNASFFDNISCETLDKQQGKDEKVDREKLRMLDVDTFGIAAAHYRSNMYNRNKNRNKIRNNRNNKMMNSFNYNYYNRNQNPFNRYAAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU84</accession>
    <name>A0A1J1GU84_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="7">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00301500</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528611.1">
        <property type="nucleotide sequence ID" value="XM_028672016.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU84"/>
    <dbReference type="GeneID" id="39731548"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00301500"/>
    <dbReference type="OrthoDB" id="10261556at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17920">
        <property type="entry name" value="DEXHc_RecQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002059">
        <property type="entry name" value="ADP-dependent DNA helicase RecQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004589">
        <property type="entry name" value="DNA_helicase_ATP-dep_RecQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018982">
        <property type="entry name" value="RQC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00614">
        <property type="entry name" value="recQ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710:SF120">
        <property type="entry name" value="BIFUNCTIONAL 3'-5' EXONUCLEASE_ATP-DEPENDENT HELICASE WRN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710">
        <property type="entry name" value="DNA HELICASE RECQ FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09382">
        <property type="entry name" value="RQC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00956">
        <property type="entry name" value="RQC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="HRDC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="57"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="265"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="895"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="900"/>
            <end position="915"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG95803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1276" mass="149118" checksum="CA7FAE3AA07D484C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUF9</accession>
    <name>A0A1J1GUF9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Chloroquine resistance marker protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00207800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527496.1">
        <property type="nucleotide sequence ID" value="XM_028670778.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUF9"/>
    <dbReference type="GeneID" id="39730605"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00207800"/>
    <dbReference type="OMA" id="DNGNRMM"/>
    <dbReference type="OrthoDB" id="19261at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15861">
        <property type="entry name" value="SNARE_SNAP25N_23N_29N_SEC9N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044766">
        <property type="entry name" value="NPSN/SNAP25-like_N_SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230:SF1">
        <property type="entry name" value="GOLGI SNAP RECEPTOR COMPLEX MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230">
        <property type="entry name" value="VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="9">
        <location>
            <begin position="123"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="154"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG94681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="219" mass="26044" checksum="B7BEC2D71C7FA799" modified="2017-02-15" version="1">MNEIYYYSEEIDNLLEDYRKLLNDLQNESCEEKTNKYCNDINFITERIKTTKDAYFIEVRNLPEKDQNNHILKIKGKMSILENLNLEFDFIKSKLRYEKNEEKKNKIVKEKYLTPKEIEIRGDLIQDHTNESIYRMKKMVDESEQITIDAINKLNVQNEKLQEVTDNVDDVEMNISHAKQTLREIAKEAITDRFVRLLALLIFIVLIVLIAIIAIPRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUS6</accession>
    <name>A0A1J1GUS6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00320800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000047">
        <property type="protein sequence ID" value="CRG95995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528803.1">
        <property type="nucleotide sequence ID" value="XM_028672230.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUS6"/>
    <dbReference type="GeneID" id="39731741"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00320800"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="323" mass="38616" checksum="290B9C0A89622FDC" modified="2017-02-15" version="1">MALLYNEGCENFEEDSAICRMNICPIKQSKFQKSLCDIGMPFVKMYRPLNNASNDISKNIFKYERYGRYGYSRIIILSNDYQDGIVFLYEYNIHYDPYPTKTYLCRLRNINQTAALCESVDMYYLDKRLSFSSYDIINGKNDQPLKHLKNPNHKIIKLNYKNLFIKEHSCHHIKTRYISDHNCMYAICEKKNEDYMLCSDANYSGKLIFLHSANQKYKKFMYLPERCLTRDSNLACVPYYCETNAKDKFFPCEHKEISVIKDIMPYAKRSEVMPIKQQIVHHEDNLSASALFAMTLMPFLILFVFFWCYLYKNFKKRRRRKIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV29</accession>
    <name>A0A1J1GV29_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">D-aminoacyl-tRNA deacylase</fullName>
            <ecNumber evidence="2 5">3.1.1.96</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00335500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a D-aminoacyl-tRNA + H2O = a tRNA + a D-alpha-amino acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13953"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:10124"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59871"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:79333"/>
            <dbReference type="EC" id="3.1.1.96"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>glycyl-tRNA(Ala) + H2O = tRNA(Ala) + glycine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53744"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:13640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
            <dbReference type="EC" id="3.1.1.96"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the DTD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.96" evidence="2 5"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528945.1">
        <property type="nucleotide sequence ID" value="XM_028672387.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV29"/>
    <dbReference type="GeneID" id="39731885"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00335500"/>
    <dbReference type="OMA" id="VFGADMK"/>
    <dbReference type="OrthoDB" id="275783at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051500">
        <property type="term" value="F:D-tyrosyl-tRNA(Tyr) deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106026">
        <property type="term" value="F:Gly-tRNA(Ala) deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.80.10:FF:000001">
        <property type="entry name" value="D-aminoacyl-tRNA deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.80.10">
        <property type="entry name" value="D-tyrosyl-tRNA(Tyr) deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003732">
        <property type="entry name" value="Daa-tRNA_deacyls_DTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023509">
        <property type="entry name" value="DTD-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00256">
        <property type="entry name" value="D-aminoacyl-tRNA deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10472:SF5">
        <property type="entry name" value="D-AMINOACYL-TRNA DEACYLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10472">
        <property type="entry name" value="D-TYROSYL-TRNA TYR DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02580">
        <property type="entry name" value="Tyr_Deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69500">
        <property type="entry name" value="DTD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0820">tRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="166" mass="19443" checksum="A39F5E3C1023B07D" modified="2017-02-15" version="1">MRVIIQRVKNAILRVKKEPIHENENKNELEVFSKINEGLICFIGIHRDDTWKDALYIIKKCLNLRLWSNNDKSWDKSVKDLDYEILLVSQFTLFANTKKGSKPDFHLAKESNEALIFFNKIVEEFVKEYKQEKIKTGKFGCHMNIEVTNDGPVTIFIDSHDISLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV31</accession>
    <name>A0A1J1GV31_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00363300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529214.1">
        <property type="nucleotide sequence ID" value="XM_028672686.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV31"/>
    <dbReference type="GeneID" id="39732163"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00363300"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="72" mass="8302" checksum="80083C1FF2E8214F" modified="2017-02-15" version="1">MVQNLKVKVKKSKITERKNKSKKSKKNKEKIVVKSLRKKSKLVKINKIEEMAKKLCSSANNTLKFINGKSDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVE9</accession>
    <name>A0A1J1GVE9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AMP deaminase</fullName>
            <ecNumber evidence="4">3.5.4.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00241700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via salvage pathway; IMP from AMP: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.6" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527832.1">
        <property type="nucleotide sequence ID" value="XM_028671151.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVE9"/>
    <dbReference type="GeneID" id="39730945"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00241700"/>
    <dbReference type="OMA" id="FHRKFPY"/>
    <dbReference type="OrthoDB" id="1723809at2759"/>
    <dbReference type="UniPathway" id="UPA00591">
        <property type="reaction ID" value="UER00663"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003876">
        <property type="term" value="F:AMP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046033">
        <property type="term" value="P:AMP metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032264">
        <property type="term" value="P:IMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.800.20:FF:000002">
        <property type="entry name" value="AMP deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000035">
        <property type="entry name" value="Probable amp deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.800.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006650">
        <property type="entry name" value="A/AMP_deam_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006329">
        <property type="entry name" value="AMPD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01429">
        <property type="entry name" value="AMP_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11359">
        <property type="entry name" value="AMP DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11359:SF0">
        <property type="entry name" value="AMP DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19326">
        <property type="entry name" value="AMP_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00485">
        <property type="entry name" value="A_DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="693" mass="81056" checksum="11E0B5099007E754" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVN3</accession>
    <name>A0A1J1GVN3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glycine cleavage H protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">GCVH</name>
        <name evidence="5" type="ORF">PGAL8A_00360400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GcvH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529185.1">
        <property type="nucleotide sequence ID" value="XM_028672654.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVN3"/>
    <dbReference type="GeneID" id="39732134"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00360400"/>
    <dbReference type="OMA" id="KEHEWIR"/>
    <dbReference type="OrthoDB" id="10264154at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005960">
        <property type="term" value="C:glycine cleavage complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06848">
        <property type="entry name" value="GCS_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002930">
        <property type="entry name" value="GCV_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033753">
        <property type="entry name" value="GCV_H/Fam206"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11715">
        <property type="entry name" value="GLYCINE CLEAVAGE SYSTEM H PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11715:SF3">
        <property type="entry name" value="GLYCINE CLEAVAGE SYSTEM H PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01597">
        <property type="entry name" value="GCV_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="4">
        <location>
            <begin position="52"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="196" mass="23059" checksum="7C9DE72CCD33FEEC" modified="2017-02-15" version="1">MLRFKRGFPYNSFNFFYVQNSFKKFITYYTKTHEYIKINEENLKDLKNKNIKCKIGISNYGTEKLGEIVYIDIIYNINDYVKKGDCIATIESVKSVGDVYTPISGKITNINNKIIDNINLMNKSSESDGWIIELLTNDIDEKEILDISEYKKICDEEEEKEETKIQQNEINSLEEKNKNKIFDINDIKSIEDKEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVQ2</accession>
    <name>A0A1J1GVQ2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00013100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528173.1">
        <property type="nucleotide sequence ID" value="XM_028671529.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVQ2"/>
    <dbReference type="GeneID" id="39728653"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00013100"/>
    <dbReference type="OMA" id="NDHICSN"/>
    <dbReference type="OrthoDB" id="377824at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="710"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="827"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="866"/>
            <end position="884"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="920" mass="113297" checksum="0F24B72290C3B462" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW18</accession>
    <name>A0A1J1GW18_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">OTU domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00261600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528024.1">
        <property type="nucleotide sequence ID" value="XM_028671364.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW18"/>
    <dbReference type="GeneID" id="39731145"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00261600"/>
    <dbReference type="OMA" id="CHVETCG"/>
    <dbReference type="OrthoDB" id="372228at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="442"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="452"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="941" mass="112231" checksum="7B32F4AA1BF54695" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW24</accession>
    <name>A0A1J1GW24_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00270000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000039">
        <property type="protein sequence ID" value="CRG95500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528309.1">
        <property type="nucleotide sequence ID" value="XM_028671681.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW24"/>
    <dbReference type="GeneID" id="39731232"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00270000"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012385039" evidence="2">
        <location>
            <begin position="22"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="184" mass="21163" checksum="88A3E97ACDFF45FB" modified="2017-02-15" version="1">MSALFYLVVLQNFLFCLLVVSFRTNVEDIASFFLRGPYKISFGEPYITGEVFDVNNEENHSLDSEENQVIGEEVEKETEETHKKTGDVVTEISEVNKETREAYVDAEELNKDAEKENKNIEKVNKNEEVDREAGEVDREEGEVDKEAGEVEKEAGEVDREEGEVDREEGEVDREEVSTFFFFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW39</accession>
    <name>A0A1J1GW39_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-i protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00271700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000041">
        <property type="protein sequence ID" value="CRG95516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528325.1">
        <property type="nucleotide sequence ID" value="XM_028671698.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW39"/>
    <dbReference type="GeneID" id="39731248"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00271700"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="119"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="241" mass="28905" checksum="722199D5ACE28A45" modified="2017-02-15" version="1">MDLNLSDIIYIDSCETLDEEDSTAGFDHREIKDATVSIPENPLHDNLNSCDAIQNPSKDINLDSATSINVLHKKSYNIFQLAIIIISILRFRARSTKWKAKRERDRLQKIWDNSSKKMKGDLEKKMLDEKNKMEKNEKKLLKKKKEMEEWEKGVLREKEVWERRTRKEKQECGESMLKQLEDWEKRVLQKGEDWEKRKLIEKEKLEKKILKNREEGEEKMLEIMKTLEEKILKEKKSEKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW53</accession>
    <name>A0A1J1GW53_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00371900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529299.1">
        <property type="nucleotide sequence ID" value="XM_028672781.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732249"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00371900"/>
    <dbReference type="OMA" id="CPIKNEV"/>
    <dbReference type="OrthoDB" id="372378at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="303"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1158"/>
            <end position="1185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1488" mass="177097" checksum="DE78A305D5BD76A3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWA1</accession>
    <name>A0A1J1GWA1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein-lysine N-methyltransferase PGAL8A_00429500</fullName>
            <ecNumber evidence="5">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00429500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that methylates elongation factor 1-alpha.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529519.1">
        <property type="nucleotide sequence ID" value="XM_028673025.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWA1"/>
    <dbReference type="GeneID" id="39732827"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00429500"/>
    <dbReference type="OMA" id="PTPSFQF"/>
    <dbReference type="OrthoDB" id="540004at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03188">
        <property type="entry name" value="Methyltr_EFM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026635">
        <property type="entry name" value="Efm4/METTL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12843:SF5">
        <property type="entry name" value="EEF1A LYSINE METHYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12843">
        <property type="entry name" value="PROTEIN-LYSINE N-METHYLTRANSFERASE METTL10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="6">
        <location>
            <begin position="50"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="215" mass="25483" checksum="6D388237F10E7A6D" modified="2017-02-15" version="1">MSELHKLSYWEEIYKNEKKNYEESNIELEEWFEENCDKIINWIETNFKEQKNIAILDIGCGNGLFLYKLYEKGFVNLHGLDFSNTAIELSKKLFNNININLEVLDICNIEKEIHKSKLNKNYNLLNDKGTFDIFFMNNKENEYFKQISFFLQINTVFCITSCNACKEEILQIIKNFNDNNNYKFKLSLIDEISYETISFSGKTGQIITTLIFRCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWH3</accession>
    <name>A0A1J1GWH3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATPase AAA-type core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00012600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528168.1">
        <property type="nucleotide sequence ID" value="XM_028671524.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWH3"/>
    <dbReference type="GeneID" id="39728648"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00012600"/>
    <dbReference type="OrthoDB" id="377837at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="582" mass="69591" checksum="FCD7445C59DB2607" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWM6</accession>
    <name>A0A1J1GWM6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00442500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529647.1">
        <property type="nucleotide sequence ID" value="XM_028673167.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWM6"/>
    <dbReference type="GeneID" id="39732958"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00442500"/>
    <dbReference type="OMA" id="DIIEYPC"/>
    <dbReference type="OrthoDB" id="336729at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="350" mass="40728" checksum="198532BA3009818A" modified="2017-02-15" version="1">MKLNELNICIQVKCISFCSSIFFPNNVKKNGYNNNDIEKKNLDECEENNNIKLKYLIGNIYIGKVINVGENVDNIIKGKNVIGIFTVNSKIKNDEIIAPYHDIIEYPCNELKNDYSLCASFRSLYESYLCLSVINHNKMLKYIAIFAENVLQVLPLLKMLLKNQVFIIIFLPKENCLQNRIKNSLEEYHISNDSFKERVSIFSIDMNIPEHIHVITNRLGVKIIIVYPNLSIDKNILKKNIFTLSALNANLIFTYELDYLNPYECKLLFEKGVKIHFFNVNNYIYYDYFKRTNAFNYVLLSILNKDIDIPSVSLNKKYFSSMEEIFSSMPCGEGYNIYINKNIDCQSDNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWM9</accession>
    <name>A0A1J1GWM9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Pre-mRNA-splicing regulator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00452500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the fl(2)d family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529748.1">
        <property type="nucleotide sequence ID" value="XM_028673279.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWM9"/>
    <dbReference type="GeneID" id="39733058"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00452500"/>
    <dbReference type="OMA" id="KEICQTH"/>
    <dbReference type="OrthoDB" id="3366661at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016556">
        <property type="term" value="P:mRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000381">
        <property type="term" value="P:regulation of alternative mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033757">
        <property type="entry name" value="WTAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15217:SF0">
        <property type="entry name" value="PRE-MRNA-SPLICING REGULATOR WTAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15217">
        <property type="entry name" value="WILMS' TUMOR 1-ASSOCIATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17098">
        <property type="entry name" value="Wtap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="236"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="247"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="266"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="292"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="314"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="334"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="439"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="500" mass="60763" checksum="A157E204C0E26F9C" modified="2017-02-15" version="1">MSQENNEVIMNDEANEYTEENLNEHFNEFKKREHVYLACISSLEKEICQTHTYLNEWRSMHMYDDEDNKSSKDIININSLRNILIDPCINLEIKELRQKVYEITRKCNLAEEKLQGCNFDAQATAGQRLINKCKKLQEENYELGKTLEENNLQSLSIQILNLKQQIVFYKNELKILKELNADIDEDNELLSQQLAELTKKYTQVTEEKNELEKSNLKLNNYIDSLKSKLSKYNEISKDEQRHKKKNNYYYNSSENNANNEINNNEENQEEYKDEEEEYAEEMEDNDNEEDENYQKNEDFAERKEEEEEYTNENDSYKKKNSDESRDRKHRKLDKHYYKDKKYDKDKYKLREKEKEKNRKDRIREKEKTKERIKEKLKEREKTKNKYKNRNKEKIKSKTKKEQYDGNYLEQKRKFTKDHDNDFRETPRTDKFDNSNNVSKNDDMEDKTSECGSERERSCRKKERSKNKYKEKYKSRKRIKIRSNDEKEDDDAYDKKSNGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWP3</accession>
    <name>A0A1J1GWP3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00292900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528533.1">
        <property type="nucleotide sequence ID" value="XM_028671929.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWP3"/>
    <dbReference type="GeneID" id="39731462"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00292900"/>
    <dbReference type="OrthoDB" id="10255128at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.910.10">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016084">
        <property type="entry name" value="Haem_Oase-like_multi-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050967">
        <property type="entry name" value="Thiamine_Salvage_TenA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43198">
        <property type="entry name" value="BIFUNCTIONAL TH2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43198:SF2">
        <property type="entry name" value="SI:CH1073-67J19.1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48613">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="945" mass="115107" checksum="759D9C2104546B63" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWP5</accession>
    <name>A0A1J1GWP5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcription factor with AP2 domain(S), putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ApiAP2</name>
        <name evidence="7" type="ORF">PGAL8A_00447600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529698.1">
        <property type="nucleotide sequence ID" value="XM_028673224.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWP5"/>
    <dbReference type="GeneID" id="39733009"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00447600"/>
    <dbReference type="OrthoDB" id="430533at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00847">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="6">
        <location>
            <begin position="120"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="210" mass="25569" checksum="CC4F3CB741A181C5" modified="2017-02-15" version="1">MLSRLVVKSNNLLKKIWSKNICTLSNVFLSKHPYKPKTREIIHPHMTPPEYLSPSDCFDAKTSELQQFIPKNFYRTKWIESLRSGEYLGEDYPWNLLPKWKYWKKRKYNVKYHEIPWFISKVKGVSYYKRLNVWMVQWVENGVHRIRRFRCAFGILQAKLAAEQFRKNLEESGRVDNRKTERQLRMDYIQKKDERLLRKKKYSKISKGQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWW4</accession>
    <name>A0A1J1GWW4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CPW-WPC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00300900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528605.1">
        <property type="nucleotide sequence ID" value="XM_028672009.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWW4"/>
    <dbReference type="GeneID" id="39731542"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00300900"/>
    <dbReference type="OMA" id="DYSQNCA"/>
    <dbReference type="OrthoDB" id="368872at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006387">
        <property type="entry name" value="CPW_WPC_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01492">
        <property type="entry name" value="CPW_WPC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09717">
        <property type="entry name" value="CPW_WPC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01099">
        <property type="entry name" value="CPW_WPC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013176089" evidence="1">
        <location>
            <begin position="20"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="CPW-WPC" evidence="2">
        <location>
            <begin position="25"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="CPW-WPC" evidence="2">
        <location>
            <begin position="86"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="CPW-WPC" evidence="2">
        <location>
            <begin position="147"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="CPW-WPC" evidence="2">
        <location>
            <begin position="208"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="CPW-WPC" evidence="2">
        <location>
            <begin position="277"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="369" mass="43117" checksum="B7BF3261E54E7BDD" modified="2017-02-15" version="1">MFQNFLFFILFLIIKEAISQKNSTCLRDYSQNCAEGWSKLSKSKECVAPLSYRGPCPRFLQIEHETKKKKELEKLCNIYWPCLTYCEKNYSSECPEKWVQGDDKNCYPLATYEGTCLFSYDFSNMTDEQKEIWSNKCETMWPCKEKCKKDYSKLCPQKWIKDDNDLCSAPINYNGPCLSRASLVTLDKDMKVAFEKLCKLDYPCLKECKIDMDDPCPQNWILKSNESGTSISCLPPDEYKGICDENTKFIGLNLELKESIEYECDIKWPCAEEIPDLINYEELCPENWIQSENYCVAPQNYMGPCSKKKLFKSFRKEIKKAYAEECNIKWPLFKNSKENFPKISALRKGRYKFGIVEPITGEILSKIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWX9</accession>
    <name>A0A1J1GWX9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Dynein intermediate chain 2, ciliary, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00434900</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynein intermediate chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529571.1">
        <property type="nucleotide sequence ID" value="XM_028673082.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWX9"/>
    <dbReference type="GeneID" id="39732881"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00434900"/>
    <dbReference type="OMA" id="YWSQGEV"/>
    <dbReference type="OrthoDB" id="24670at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036157">
        <property type="term" value="C:outer dynein arm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045504">
        <property type="term" value="F:dynein heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045503">
        <property type="term" value="F:dynein light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003341">
        <property type="term" value="P:cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036158">
        <property type="term" value="P:outer dynein arm assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050687">
        <property type="entry name" value="Dynein_IC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442:SF11">
        <property type="entry name" value="DYNEIN AXONEMAL INTERMEDIATE CHAIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442">
        <property type="entry name" value="DYNEIN INTERMEDIATE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0243">Dynein</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8" id="KW-0505">Motor protein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="617"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="183"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="229"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="25"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="183"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="232"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="274"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG96767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="773" mass="91725" checksum="201F2E5EB95855E0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXD6</accession>
    <name>A0A1J1GXD6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">26S protease regulatory subunit 8, putative</fullName>
            <ecNumber evidence="13">3.6.4.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">RPT6</name>
        <name evidence="13" type="ORF">PGAL8A_00469700</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.8" evidence="13"/>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529919.1">
        <property type="nucleotide sequence ID" value="XM_028673470.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXD6"/>
    <dbReference type="GeneID" id="39733230"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00469700"/>
    <dbReference type="OMA" id="REPAVIF"/>
    <dbReference type="OrthoDB" id="1154031at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19502">
        <property type="entry name" value="RecA-like_PAN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000006">
        <property type="entry name" value="26S protease regulatory subunit 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000044">
        <property type="entry name" value="26S protease regulatory subunit 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000030">
        <property type="entry name" value="26S protease regulatory subunit 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032501">
        <property type="entry name" value="Prot_ATP_ID_OB_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16450">
        <property type="entry name" value="Prot_ATP_ID_OB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-0647">Proteasome</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="12">
        <location>
            <begin position="199"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="45"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG97116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="422" mass="48129" checksum="935ABA853C4CED6D" modified="2017-02-15" version="1">MAAVDMQIRSNTIPEKTKKENNKNNSNKNEEEIQSGIKTYYELKIEEYESIINKKLQNKKRLEAQRNELNTRVRELCDEIQYLLEAASYVGEIVKPMGKNKVLVKINPEGKYVVDIARHINISQCTPNTRVALYNDSYKLHKILPSKVDPLVSLMKVEKVPDSTYEMVGGLDQQVKEVKEVIELPVKHPEIFESLGISQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKYIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSQRIEGEHGDSEVQRTMMELLNQLDGFESTQNIKVIMCTNRIDILDEALLRPGRIDRKIEFPNPNVEARIEILKIHSRKMNLMRGIDMVKIATDMNNCSGAEVKAVCTEAGMFALRERRVHVTQEDFEMAVAKVMKQDAEKNFTLRKLWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXP2</accession>
    <name>A0A1J1GXP2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00491700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530140.1">
        <property type="nucleotide sequence ID" value="XM_028673715.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXP2"/>
    <dbReference type="GeneID" id="39733450"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00491700"/>
    <dbReference type="OrthoDB" id="364143at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="635" mass="77337" checksum="1E0B2F91D4E59E39" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXT1</accession>
    <name>A0A1J1GXT1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00486700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530090.1">
        <property type="nucleotide sequence ID" value="XM_028673660.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXT1"/>
    <dbReference type="GeneID" id="39733400"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00486700"/>
    <dbReference type="OrthoDB" id="368328at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="71" mass="8502" checksum="1D57B24B364C079E" modified="2017-02-15" version="1">MSITAGKCCKYIRKYFTNGLRKNALPYFIYCKNKPFLINPKLIQKYSLDNVPKNVINRYIQDKRRLKNDNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXT6</accession>
    <name>A0A1J1GXT6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Dynein heavy chain C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00484800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530071.1">
        <property type="nucleotide sequence ID" value="XM_028673638.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733381"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00484800"/>
    <dbReference type="OMA" id="KIFHINQ"/>
    <dbReference type="OrthoDB" id="377933at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.180.20">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042228">
        <property type="entry name" value="Dynein_linker_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703">
        <property type="entry name" value="DYNEIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703:SF36">
        <property type="entry name" value="DYNEIN HEAVY CHAIN, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2190"/>
            <end position="2210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2227"/>
            <end position="2255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2816"/>
            <end position="2839"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3322"/>
            <end position="3355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3453"/>
            <end position="3497"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3076"/>
            <end position="3103"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3218"/>
            <end position="3245"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3755"/>
            <end position="3794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2227"/>
            <end position="2240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="2241"/>
            <end position="2252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="3331"/>
            <end position="3341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="3342"/>
            <end position="3355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="3461"/>
            <end position="3490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="4777" mass="579450" checksum="E60B5A997AF7043D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXT8</accession>
    <name>A0A1J1GXT8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">pyruvate kinase</fullName>
            <ecNumber evidence="4">2.7.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">PyKII</name>
        <name evidence="16" type="ORF">PGAL8A_00495700</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the pyruvate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.40" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530180.1">
        <property type="nucleotide sequence ID" value="XM_028673760.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXT8"/>
    <dbReference type="GeneID" id="39733490"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00495700"/>
    <dbReference type="OMA" id="MIMPIEV"/>
    <dbReference type="OrthoDB" id="108365at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00188"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004743">
        <property type="term" value="F:pyruvate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.33.10">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.20">
        <property type="entry name" value="Pyruvate kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001697">
        <property type="entry name" value="Pyr_Knase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018209">
        <property type="entry name" value="Pyrv_Knase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015793">
        <property type="entry name" value="Pyrv_Knase_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015795">
        <property type="entry name" value="Pyrv_Knase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036918">
        <property type="entry name" value="Pyrv_Knase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015806">
        <property type="entry name" value="Pyrv_Knase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11817">
        <property type="entry name" value="PYRUVATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00224">
        <property type="entry name" value="PK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02887">
        <property type="entry name" value="PK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52935">
        <property type="entry name" value="PK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00110">
        <property type="entry name" value="PYRUVATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="8 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12 16" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="5 16" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012701223" description="pyruvate kinase" evidence="13">
        <location>
            <begin position="20"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate kinase barrel" evidence="14">
        <location>
            <begin position="84"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate kinase barrel" evidence="14">
        <location>
            <begin position="419"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate kinase C-terminal" evidence="15">
        <location>
            <begin position="592"/>
            <end position="691"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="CRG97378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="714" mass="83240" checksum="A973E889F1BB475D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXT9</accession>
    <name>A0A1J1GXT9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nucleolar preribosomal assembly protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00487500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EBP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530098.1">
        <property type="nucleotide sequence ID" value="XM_028673669.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXT9"/>
    <dbReference type="GeneID" id="39733408"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00487500"/>
    <dbReference type="OrthoDB" id="443772at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034399">
        <property type="term" value="C:nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008610">
        <property type="entry name" value="Ebp2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13028">
        <property type="entry name" value="RRNA PROCESSING PROTEIN EBNA1-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13028:SF0">
        <property type="entry name" value="RRNA-PROCESSING PROTEIN EBP2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05890">
        <property type="entry name" value="Ebp2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="297"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="298"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="312"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="345" mass="41444" checksum="585997FB0F05F6AA" modified="2017-02-15" version="1">MRDMKFPLNVESYKKKNNKKVENFNNNETSNDIEIKRKNMKKEKNNNYIARKNFVKKIIKKDVKSVLSTLNLTEKKKIKKKKNKKHNSNMGFNLKNEYIKNKIENKPNGDIKDDEIYKESDDKLGDFNQNKVLLVKKLQEIELKSNNPNEWLEKLDITSSEHFYMKNINLFGNCEKREEEFLQIAHKNLIEALKKLQDLNISFNRPYDFLADMIKSDIHMEKVRQKILKDHEKSEIREKNKLKRINKKFNKKCGSLKVKNQKEAIQKKKNLEKIDELKKNNNLESLNVQEFFLKHSKSSNDKSINKNDKNRKVDKKWTKRNFTKKKNEKKFAKKFKKKNNFKKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXW3</accession>
    <name>A0A1J1GXW3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fam-h protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00497900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000102">
        <property type="protein sequence ID" value="CRG97404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530206.1">
        <property type="nucleotide sequence ID" value="XM_028673789.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXW3"/>
    <dbReference type="GeneID" id="39733512"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00497900"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="139" mass="16459" checksum="88B203EBAAACEB26" modified="2017-02-15" version="1" fragment="single">SAEHIFKKSKSESTENLLDALEKEEINEKPDEMEKNLIKSKAQKSIFHSFNIPKPSETIVEILNENNVNKQKVTKYINKSIGSFFFSLISLSLPLYLVYLSHMEYFYNWKEHSERYRFLMSYCILMISCFICLLYHKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY17</accession>
    <name>A0A1J1GY17_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PNAS-3 related protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00503100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530259.1">
        <property type="nucleotide sequence ID" value="XM_028673847.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY17"/>
    <dbReference type="GeneID" id="39733564"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00503100"/>
    <dbReference type="OMA" id="WIKGINV"/>
    <dbReference type="OrthoDB" id="340500at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071034">
        <property type="term" value="P:CUT catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071051">
        <property type="term" value="P:poly(A)-dependent snoRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22526">
        <property type="entry name" value="KH-I_Rrp40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026699">
        <property type="entry name" value="Exosome_RNA_bind1/RRP40/RRP4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049469">
        <property type="entry name" value="RRP40_KH-I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21321:SF1">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21321">
        <property type="entry name" value="PNAS-3 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15985">
        <property type="entry name" value="KH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21262">
        <property type="entry name" value="RRP40_S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0271">Exosome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="161"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF15985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="244" mass="28136" checksum="F578F5DE8554B843" modified="2017-02-15" version="1">MEDEVIISGDYVKIEKDKLNKINENNFEKIHNSEHENFYRSKCSGILLKTPYYPYKYEIMNTSYKYIPKVGDLVIGIVKSKKLDYYQMDINCNCDCIIHKIEGFKYATKSSFPNLVNGTLLYMIVEKINLDNNSVVASCINSSDVKSWINYENYLGELIDGFLFSVNISFSKSLIGDRCYILDLIGQDINYEIAIGHNGRVWIKSNEPLETNLIYSALKHSFGKTKAQMDVLWKSIYNLSKKST</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY53</accession>
    <name>A0A1J1GY53_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rhoptry neck protein 4, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RON4</name>
        <name evidence="3" type="ORF">PGAL8A_00342600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529013.1">
        <property type="nucleotide sequence ID" value="XM_028672463.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY53"/>
    <dbReference type="GeneID" id="39731956"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00342600"/>
    <dbReference type="OrthoDB" id="372438at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012385031" evidence="2">
        <location>
            <begin position="24"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="305"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="341"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="376"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="418"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="454"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="947" mass="109274" checksum="D9FE60581507D2B1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYG5</accession>
    <name>A0A1J1GYG5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fam-i protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00327200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000053">
        <property type="protein sequence ID" value="CRG96056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528864.1">
        <property type="nucleotide sequence ID" value="XM_028672297.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYG5"/>
    <dbReference type="GeneID" id="39731802"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00327200"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="120"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="196"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="251" mass="29912" checksum="C8691D6048459F6A" modified="2017-02-15" version="1">MALNHSDAISIESSERLNEGDSTAGFAHRAIKDETASIPENPLHDDLNSRDAIQNPSKDINLDSATSKNLLHKKSLSIFQLVIIIIAFLRFKRPHSLKLKAKHERDRLQKIWDNSSKEMKGDLEEKMLEEKKKMEENEKKLLKKLKKIEVREKIILKKKEEWEKRTLKEKQECDESILKELEEWDKRILIKREDWEKRMLIEKEKLEKEILKNKEEGEEKMLKIMEKLEKKMLKEKESGWLIKGFINLFRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYP6</accession>
    <name>A0A1J1GYP6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein AMR3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00501200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530240.1">
        <property type="nucleotide sequence ID" value="XM_028673826.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYP6"/>
    <dbReference type="GeneID" id="39733545"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00501200"/>
    <dbReference type="OMA" id="INFKCKN"/>
    <dbReference type="OrthoDB" id="383193at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012181814" description="Protein AMR3" evidence="2">
        <location>
            <begin position="21"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="433" mass="52370" checksum="2954082A1E1A9F9A" modified="2017-02-15" version="1">MKFVLLLLDIILIFFIKILKNYERKYILVKCNKYYLKRSFNVKRNIKILNFLNLCNSRKFFKLYMTRKFKYKYRNTLEKRKRKGHIKNQINQKLKKKHSAYIVITEKLSKLDPDQKYFKYDKNILKEYENIKDIYKNRKLGRKFNQFNYWYSSNKKEAKINYSRHVNFAITNNKFNFKNVFSYFHILEIVHEKFKNNPFYINGLQAFINKYYDPVTQKRIKFYDKIKEQLEIKKKNGDINKEKDTKKNIYEKGNKSETEENLDNINITSETQKDDKINKKEDAENSNNNLDIIDENELKNDQIDDTNNFQNDEQLEKEGVTKSKSEFFELIKNNIGTLTYSHEVNDDSSFKLFGSSTSCILKKNAPLAYDIKNPFMKSKLSSKRRRFKERKLFDIINFKCKNRKERLMLNAVRKLSKRKMKNEKYVLDSLKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYR4</accession>
    <name>A0A1J1GYR4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed DNA polymerase</fullName>
            <ecNumber evidence="2">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00495600</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530179.1">
        <property type="nucleotide sequence ID" value="XM_028673759.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733489"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00495600"/>
    <dbReference type="OMA" id="CIYNIER"/>
    <dbReference type="OrthoDB" id="2414538at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016035">
        <property type="term" value="C:zeta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.60">
        <property type="entry name" value="DNA polymerase family B, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.342.10">
        <property type="entry name" value="DNA Polymerase, chain B, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017964">
        <property type="entry name" value="DNA-dir_DNA_pol_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006134">
        <property type="entry name" value="DNA-dir_DNA_pol_B_multi_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042087">
        <property type="entry name" value="DNA_pol_B_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056435">
        <property type="entry name" value="DPOD/Z_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030559">
        <property type="entry name" value="PolZ_Rev3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45812">
        <property type="entry name" value="DNA POLYMERASE ZETA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45812:SF1">
        <property type="entry name" value="DNA POLYMERASE ZETA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00136">
        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24055">
        <property type="entry name" value="POL3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00116">
        <property type="entry name" value="DNA_POLYMERASE_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 12" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA polymerase delta/zeta catalytic subunit N-terminal" evidence="11">
        <location>
            <begin position="66"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B multifunctional" evidence="10">
        <location>
            <begin position="1137"/>
            <end position="1231"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B multifunctional" evidence="10">
        <location>
            <begin position="1350"/>
            <end position="1564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="461"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="353"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="474"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF24055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG97377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2119" mass="253397" checksum="63E361962ABC782D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYY2</accession>
    <name>A0A1J1GYY2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00534200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530565.1">
        <property type="nucleotide sequence ID" value="XM_028674186.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYY2"/>
    <dbReference type="GeneID" id="39733875"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00534200"/>
    <dbReference type="OMA" id="AHVYNGN"/>
    <dbReference type="OrthoDB" id="371684at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="3">
        <location>
            <begin position="290"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="290"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="368"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="368"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="451" mass="52840" checksum="3C80B5A5C48A2195" modified="2017-02-15" version="1">MNVVSPITKYSFSEKNLNKNLTVMDEEKYKDYDTYLQKKESIYDSLIHLKHEDEKNCFDVNSEICRTESNYADFSTRKVKYVVNKRFSEFENIEKNIEDIDYSLFKYFRTLPPKYSDENDIRNNIIFNNNNIYIYAENKNGTLNEQACISISPDNNIIYCSTKGRRYTIGGHAGIQKNVNNEYNFFEDNNSLSPQDSIKTYTFDAIDSSDISSSFTKMNLIKTNDVLDDCNINKINTGNIFNEHIILNSCGSSNLNTTKCLSKNFSVQKLFKHYKKCSQNLEHEQRICKPCAHVYNGNTCMNGDDCLFCHHPDHVLISAKKWKKLVKNNMEKLNILLHILRNPDDANANLLNEMLKQNTKNFKKNKKLNNNNNINNKKLMNNNDNSNKKNKNNKSKIYYFPQKNVDKLLNSSYNNYESNETTDTYKSKFHIRNHNVYMERNANFVPYNLNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZC2</accession>
    <name>A0A1J1GZC2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">60S ribosomal protein L12, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00038500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530747.1">
        <property type="nucleotide sequence ID" value="XM_028674389.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZC2"/>
    <dbReference type="GeneID" id="39728909"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00038500"/>
    <dbReference type="OMA" id="QPPHDVI"/>
    <dbReference type="OrthoDB" id="1478556at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00349">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.250:FF:000002">
        <property type="entry name" value="60S ribosomal protein L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1550.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.250">
        <property type="entry name" value="Ribosomal protein L11, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="entry name" value="Ribosomal protein L11/L12, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00736">
        <property type="entry name" value="Ribosomal_uL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000911">
        <property type="entry name" value="Ribosomal_uL11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020783">
        <property type="entry name" value="Ribosomal_uL11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036769">
        <property type="entry name" value="Ribosomal_uL11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020785">
        <property type="entry name" value="Ribosomal_uL11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_uL11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_uL11_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00298">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00649">
        <property type="entry name" value="RL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="Ribosomal L11/L12e N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46906">
        <property type="entry name" value="Ribosomal protein L11, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00359">
        <property type="entry name" value="RIBOSOMAL_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL11 N-terminal" evidence="6">
        <location>
            <begin position="13"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL11 C-terminal" evidence="5">
        <location>
            <begin position="74"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="165" mass="18177" checksum="9763C4CEA4386750" modified="2017-02-15" version="1">MAPRPDPNEIKYVYIRQVGGEVGASSVLSPKLGPLGLSPKKIGDDIAKETQSWKGLKICVKLTIQNRQAKIEVVPTSTALILKELNEAPRDRKKVKNIKHNGNLKLEQIFSIARLMREKSRAKEFKGTVKEVLGTCNSVGCTVDGKKPTTIQEMIDSGEIEVPLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZD2</accession>
    <name>A0A1J1GZD2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Apicortin, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00039300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530755.1">
        <property type="nucleotide sequence ID" value="XM_028674397.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZD2"/>
    <dbReference type="GeneID" id="39728917"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00039300"/>
    <dbReference type="OMA" id="FRNGDEH"/>
    <dbReference type="OrthoDB" id="548799at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046785">
        <property type="term" value="P:microtubule polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01617">
        <property type="entry name" value="DCX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.230">
        <property type="entry name" value="Doublecortin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003533">
        <property type="entry name" value="Doublecortin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036572">
        <property type="entry name" value="Doublecortin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008907">
        <property type="entry name" value="TPP/p25"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03607">
        <property type="entry name" value="DCX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05517">
        <property type="entry name" value="p25-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00537">
        <property type="entry name" value="DCX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89837">
        <property type="entry name" value="Doublecortin (DC)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50309">
        <property type="entry name" value="DC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Doublecortin" evidence="1">
        <location>
            <begin position="169"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="261" mass="30395" checksum="AC15347FC9AB6BB8" modified="2017-02-15" version="1">MENHRDLSKYKKSIKYKIDNNYNKYVGISKDVYNSDEDALKPIKHYFFDSDEDFQSVLLEKSKKKKNEQNCNHTNLLDIKTNRKYKNVFDRLTDTNFYTGIHKERFDELGNGRGKAGTTDIYIHDGWTQAKTRNHEIYSSDIKKSKKNPVVTPGTLGIQKYGIQIASPKNIWIFRNGDKHHNGILFLVKPHINNLKTLFFEITKVLSPTIGPIRKIYDQNFRLVRSVEHLVEGAKYLCTSGDPPAPIDRLQLFLSKWVIQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZU8</accession>
    <name>A0A1J1GZU8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00053900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530901.1">
        <property type="nucleotide sequence ID" value="XM_028674561.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729064"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00053900"/>
    <dbReference type="OrthoDB" id="431852at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007309">
        <property type="entry name" value="TFIIIC_Bblock-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04182">
        <property type="entry name" value="B-block_TFIIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="208"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="255"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="3052"/>
            <end position="3077"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="3165"/>
            <end position="3188"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="4">
        <location>
            <begin position="1681"/>
            <end position="1709"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1757"/>
            <end position="1807"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1939"/>
            <end position="1973"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG98104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3346" mass="403954" checksum="1C049C29797BADAD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H017</accession>
    <name>A0A1J1H017_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Zinc finger protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00419200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529416.1">
        <property type="nucleotide sequence ID" value="XM_028672911.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H017"/>
    <dbReference type="GeneID" id="39732724"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00419200"/>
    <dbReference type="OMA" id="NYGMCNN"/>
    <dbReference type="OrthoDB" id="410307at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="50"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="120"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="50"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="120"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="170"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="432"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="170"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="443"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="517" mass="60238" checksum="7AA0DC180B694DC4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H021</accession>
    <name>A0A1J1H021_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00377800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000152">
        <property type="protein sequence ID" value="CRG98222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028531019.1">
        <property type="nucleotide sequence ID" value="XM_028674692.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H021"/>
    <dbReference type="GeneID" id="39732308"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00377800"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="210" mass="24973" checksum="5499F6FB4E792A12" modified="2017-02-15" version="1">MNILKAFNFYIILLVPYFLVFIPDFRLSPKSLKHILQIDYHEMKLISKRNLAESIPYVREFYSKTTDDNTFIEKDIFIDKFPYAEYLLSLELFNKVYNENYSIEQATGNMEAMLEKINSRFHFEGINIPLSEMFNIINRMTERTIEFSLESPETRKTLFKKILELEREATEELLKSLITGDEEVKINNRDNMDRILEIVHIEVPEKLPQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H045</accession>
    <name>A0A1J1H045_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00063100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530989.1">
        <property type="nucleotide sequence ID" value="XM_028674659.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H045"/>
    <dbReference type="GeneID" id="39729156"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00063100"/>
    <dbReference type="OrthoDB" id="10266058at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12230">
        <property type="entry name" value="RRM1_U2AF65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23139">
        <property type="entry name" value="RNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="490"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="798"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="37"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="49"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="160"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="187"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="201"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="245"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="286"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="315"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="809"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="851"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="867"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="903"/>
            <end position="927"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG98192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1023" mass="120716" checksum="EB7B066093B83938" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H065</accession>
    <name>A0A1J1H065_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00057200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530934.1">
        <property type="nucleotide sequence ID" value="XM_028674597.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H065"/>
    <dbReference type="GeneID" id="39729097"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00057200"/>
    <dbReference type="OMA" id="YENRKYV"/>
    <dbReference type="OrthoDB" id="406782at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG98137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="139" mass="17274" checksum="E6A601C3B44988A6" modified="2017-02-15" version="1">MYKIINNYFILNVKRNYRHYSRKKNINNINRKINDPYSDLYKMNFYGNNWKKLPNKKTKSKEYDIIKTSNNTYSYSSPYPPHINYTLEPYPESAKKFYYQNRKYLMKYKNVEYIPIQRLTYKNASKKTNWATYYLRMEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0M4</accession>
    <name>A0A1J1H0M4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">6-cysteine protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">P36</name>
        <name evidence="10" type="ORF">PGAL8A_00055000</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cell surface</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530912.1">
        <property type="nucleotide sequence ID" value="XM_028674573.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0M4"/>
    <dbReference type="GeneID" id="39729075"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00055000"/>
    <dbReference type="OMA" id="PSNCFST"/>
    <dbReference type="OrthoDB" id="368426at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2860">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010884">
        <property type="entry name" value="6_CYS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038160">
        <property type="entry name" value="6_CYS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051444">
        <property type="entry name" value="Parasite_Repro/Invasion_Surf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38796">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38796:SF1">
        <property type="entry name" value="ANCHORED PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G09600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07422">
        <property type="entry name" value="s48_45"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00970">
        <property type="entry name" value="s48_45"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51701">
        <property type="entry name" value="6_CYS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="6-Cys" evidence="9">
        <location>
            <begin position="19"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="9">
        <location>
            <begin position="171"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG98115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="313" mass="36451" checksum="BC85BCA75CC8386F" modified="2017-02-15" version="1">MFFFFFFYKMKKSFYFSIVVYLCFFLYNPIYMLDVKVLEVGNYYICNLKDYPTENCTVNYDYNKITKLLCPIDSVKKVGYNPSYCFKYLGVKDTLIINNREEKIYETLPGIILENVIKYGRNHLSIYAPFYVKEDVTIVCTCDHSNGDENITPYIKINLRTKNSFNNNEEYIKGCDYGNNKGKYKFLTKTMSQKENFTCEIEAAGGDVVGINCNNYNSNNFKGIQILPPTCFGTVSFSLSTLNFVTMNINNLLPDAKYFPEFSSSEKDKNFQKFSTTSYLWIPEKVPHEITFFCYCKYSYGVGVAIYNIKKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H163</accession>
    <name>A0A1J1H163_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00485400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530077.1">
        <property type="nucleotide sequence ID" value="XM_028673646.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H163"/>
    <dbReference type="GeneID" id="39733387"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00485400"/>
    <dbReference type="OMA" id="HTLQYIR"/>
    <dbReference type="OrthoDB" id="376060at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="178" mass="21753" checksum="EC5ED6B5A14627F1" modified="2017-02-15" version="1">MTTETLKENDINNMILNLMEKKKKETLPKKTKCKRNIKKGNPDKNQIKSNLDIFFKEQEEIYKNEEINIIDYIQKEAKNKEKELNDYYMYCQNFKKKYKNNFNDTIMKSEEIKKDLKDLHIEYLDNKILLENKRRIELDSMSNFYKEKLLEVKRQWDNKTFCDENLKNIVYDILNVIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H175</accession>
    <name>A0A1J1H175_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-hydroxyisobutyryl-CoA hydrolase</fullName>
            <ecNumber evidence="2">3.1.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00461700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-methylpropanoate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20888"/>
            <dbReference type="ChEBI" id="CHEBI:11805"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57340"/>
            <dbReference type="EC" id="3.1.2.4"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.4" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529840.1">
        <property type="nucleotide sequence ID" value="XM_028673382.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H175"/>
    <dbReference type="GeneID" id="39733150"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00461700"/>
    <dbReference type="OMA" id="CIWNGYA"/>
    <dbReference type="OrthoDB" id="1737613at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003860">
        <property type="term" value="F:3-hydroxyisobutyryl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006574">
        <property type="term" value="P:L-valine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045004">
        <property type="entry name" value="ECH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032259">
        <property type="entry name" value="HIBYL-CoA-H"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43176:SF3">
        <property type="entry name" value="3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43176">
        <property type="entry name" value="3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16113">
        <property type="entry name" value="ECH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl-CoA hydratase/isomerase" evidence="6">
        <location>
            <begin position="164"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="380"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="110"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="504" mass="59747" checksum="4C576FEEC9C636EC" modified="2017-02-15" version="1">MVKKFSLHNVNNCRLANVFDYAAKLNEKNYFFHTFLFYKNICYQKKKKISIFLTYPNRYKRNIDELDNNLYFLLKNNIKILNQMAERNGLNQIIKHNISNKKMCNNINKNIEDKNSTDKNDLNVNNENKSDEKKNMDDIIDLELSDIWSKKTLLVNYKNNIFEIILNRPDKLNALNKDMVTGLLNMIKSLDNDKRCHMIVLRSINTTSFSSGSDVKAIIENKEKGLMHLRQLYLYINYLSKFKKNFLCIWNGYVMGGGLGISMYSKHRVIHKNVIFAMPENKIGFFPDIGSCYFFKKYFGRNIGLHLGLTSLKLNEADLMNFKVCTNYIENIDLFLNELKNIKKNNLNDFNNEYHKILSKYPLKDCNVTPVLTEELVSNINKYYNSANNLEELISKLKKDNNDFCKKLLSDINNNCYFSCRFWFSYFLYNYDKTLEDILDNDYKISQYFLYHTKTFETGVTEILAKKNKSFQWNKVEEIKYMEMENIEDILMNKNFLSIKDEFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H219</accession>
    <name>A0A1J1H219_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosducin-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PhLP2</name>
        <name evidence="3" type="ORF">PGAL8A_00495300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosducin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530176.1">
        <property type="nucleotide sequence ID" value="XM_028673756.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H219"/>
    <dbReference type="GeneID" id="39733486"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00495300"/>
    <dbReference type="OMA" id="HFFHPEF"/>
    <dbReference type="OrthoDB" id="10257948at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02989">
        <property type="entry name" value="Phd_like_TxnDC9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024253">
        <property type="entry name" value="Phosducin_thioredoxin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21148">
        <property type="entry name" value="THIOREDOXIN DOMAIN-CONTAINING PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02114">
        <property type="entry name" value="Phosducin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosducin" evidence="2">
        <location>
            <begin position="41"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="213" mass="25210" checksum="57893334606900E1" modified="2017-02-15" version="1">MITKNKLTNICTTLTLEKAKEDIEKECKIIKGNKPNSNYEQFNECLNEGKEVKNTVMLDENSDEEEIRKWREKRLMEFKKKKELKKEGVYIEISEKDFLPTVLKNYNVICHFYDNSFNRCEILHSHLIKLANIHLATKFIKVEAKNCLFFMKKLNINVLPSLCLFIDGVLIHTCIGFENFGNKDNFKTKDLERYLYKKKVISNMEYSESDEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2J7</accession>
    <name>A0A1J1H2J7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Adrenodoxin-type ferredoxin, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00529200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the adrenodoxin/putidaredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530516.1">
        <property type="nucleotide sequence ID" value="XM_028674133.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2J7"/>
    <dbReference type="GeneID" id="39733825"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00529200"/>
    <dbReference type="OrthoDB" id="328524at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140647">
        <property type="term" value="P:P450-containing electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001055">
        <property type="entry name" value="Adrenodoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23426:SF72">
        <property type="entry name" value="2FE-2S FERREDOXIN-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23426">
        <property type="entry name" value="FERREDOXIN/ADRENODOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="9">
        <location>
            <begin position="42"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG97715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="99" mass="11424" checksum="390521F39B0C6853" modified="2017-02-15" version="1" fragment="single">MITKFSIFSRKIYKGNLFKKIKNNFIYFNTTKYLCTQNSDEIDVTFISQDNYEKTIKAKVGDSILKVAHDNNINIEGACEGFCACSTCHVIIDEKFYDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2U8</accession>
    <name>A0A1J1H2U8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Actin-depolymerizing factor 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ADF1</name>
        <name evidence="4" type="ORF">PGAL8A_00024700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the actin-binding proteins ADF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530612.1">
        <property type="nucleotide sequence ID" value="XM_028674239.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2U8"/>
    <dbReference type="GeneID" id="39728770"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00024700"/>
    <dbReference type="OMA" id="WIIFVIE"/>
    <dbReference type="OrthoDB" id="10249245at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015629">
        <property type="term" value="C:actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030042">
        <property type="term" value="P:actin filament depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017904">
        <property type="entry name" value="ADF/Cofilin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11913">
        <property type="entry name" value="COFILIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00102">
        <property type="entry name" value="ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADF-H" evidence="3">
        <location>
            <begin position="4"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="122" mass="13859" checksum="78C8A045CEB76452" modified="2017-02-15" version="1">MISGIRVNDTCVTEFNNMKIRKTCRWIIFVIENCEIIIHSKGTTDTLTELVDSIDKNQNIQCAYVVFDAVNKIHFFMYARGSSNSRDRMTYASSKQALLKKIEGVNVLTSVIEGVQDVADFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2012-05-16" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>H7CDX2</accession>
    <name>H7CDX2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ribosomal protein S3, putative</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Small subunit ribosomal protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rps3</name>
        <name evidence="7" type="synonym">RPS3</name>
        <name evidence="7" type="ORF">PGAL8A_API01600</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <geneLocation type="apicoplast" evidence="6"/>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Mol. Biol. Evol." volume="29" first="2095" last="2099">
            <title>The Plasmodium Apicoplast Genome: Conserved Structure and Close Relationship of P. ovale to Rodent Malaria Parasites.</title>
            <authorList>
                <person name="Arisue N."/>
                <person name="Hashimoto T."/>
                <person name="Mitsui H."/>
                <person name="Palacpac N.M.Q."/>
                <person name="Kaneko A."/>
                <person name="Kawai S."/>
                <person name="Hasegawa M."/>
                <person name="Tanabe K."/>
                <person name="Horii T."/>
            </authorList>
            <dbReference type="PubMed" id="22396524"/>
            <dbReference type="DOI" id="10.1093/molbev/mss082"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">A8</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS3 family.</text>
    </comment>
    <dbReference type="EMBL" id="AB649424">
        <property type="protein sequence ID" value="BAL70742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LN835293">
        <property type="protein sequence ID" value="CRG98231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009325458.1">
        <property type="nucleotide sequence ID" value="NC_031963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="H7CDX2"/>
    <dbReference type="GeneID" id="30315808"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_API01600"/>
    <dbReference type="OMA" id="GCFKNSL"/>
    <dbReference type="OrthoDB" id="372974at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Apicoplast API"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.32">
        <property type="entry name" value="Ribosomal protein S3, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036419">
        <property type="entry name" value="Ribosomal_S3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001351">
        <property type="entry name" value="Ribosomal_uS3_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00189">
        <property type="entry name" value="Ribosomal_S3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54821">
        <property type="entry name" value="Ribosomal protein S3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0933">Apicoplast</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Small ribosomal subunit protein uS3 C-terminal" evidence="5">
        <location>
            <begin position="149"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAL70742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG98231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="210" mass="26313" checksum="38EFFC93CA888116" modified="2012-05-16" version="1">MGQKVHPLIFRSNIYKNYLNNFYININKNKYYLINILLIYFLYYNLYRVFDYKYNYYININIYFYINKFIVIFLLFNYINLKYIFILFNYFNYYYYNIYNFICYLKIKYINNYYNNINVIMFYVKKYYIKYKSLKLIFDFIYNNFLKYNNNIKGLKIKVSGRFKNNLKTKTEIYIYGIISLNILNNNIKYLNNIINTKQGILSIKIWLNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2012-07-11" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>I2FKC5</accession>
    <name>I2FKC5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Citrate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CS</name>
        <name evidence="6" type="ORF">PGAL8A_00481800</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Gene" volume="502" first="36" last="39">
            <title>Age of the last common ancestor of extant Plasmodium parasite lineages.</title>
            <authorList>
                <person name="Hayakawa T."/>
                <person name="Tachibana S."/>
                <person name="Hikosaka K."/>
                <person name="Arisue N."/>
                <person name="Matsui A."/>
                <person name="Horii T."/>
                <person name="Tanabe K."/>
            </authorList>
            <dbReference type="PubMed" id="22555021"/>
            <dbReference type="DOI" id="10.1016/j.gene.2012.04.037"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the citrate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="AB571134">
        <property type="protein sequence ID" value="BAM15610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="I2FKC5"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00481800"/>
    <dbReference type="OMA" id="YTVIFGI"/>
    <dbReference type="OrthoDB" id="8017587at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046912">
        <property type="term" value="F:acyltransferase activity, acyl groups converted into alkyl on transfer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="entry name" value="Citrate Synthase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="entry name" value="Cytochrome P450-Terp, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019810">
        <property type="entry name" value="Citrate_synthase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055054">
        <property type="entry name" value="SNaCT10"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007128">
        <property type="entry name" value="PRK09569.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739">
        <property type="entry name" value="CITRATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739:SF8">
        <property type="entry name" value="CITRATE SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22717">
        <property type="entry name" value="SNaCT10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00143">
        <property type="entry name" value="CITRTSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="Citrate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00480">
        <property type="entry name" value="CITRATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Short NACHT-associated C-terminal" evidence="4">
        <location>
            <begin position="99"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAM15610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="559" mass="64808" checksum="A0CE49FDA2A48B8F" modified="2012-07-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL38</accession>
    <name>A0A1J1GL38_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00073900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525857.1">
        <property type="nucleotide sequence ID" value="XM_028675012.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729264"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00073900"/>
    <dbReference type="OMA" id="PNNREYS"/>
    <dbReference type="OrthoDB" id="392684at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="804"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1087"/>
            <end position="1115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1429"/>
            <end position="1473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1497"/>
            <end position="1537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2205"/>
            <end position="2244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2266"/>
            <end position="2806"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2831"/>
            <end position="2962"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1559"/>
            <end position="1667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="810"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1097"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1432"/>
            <end position="1444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1453"/>
            <end position="1464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1504"/>
            <end position="1513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2205"/>
            <end position="2225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2269"/>
            <end position="2282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2284"/>
            <end position="2296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2308"/>
            <end position="2326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2357"/>
            <end position="2371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2372"/>
            <end position="2385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2415"/>
            <end position="2762"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2768"/>
            <end position="2779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2794"/>
            <end position="2803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2833"/>
            <end position="2863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="2906"/>
            <end position="2919"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="2928"/>
            <end position="2937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2938"/>
            <end position="2953"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3299" mass="385325" checksum="667C070B6A4201DC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL98</accession>
    <name>A0A1J1GL98_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00088600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526004.1">
        <property type="nucleotide sequence ID" value="XM_028671399.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729410"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00088600"/>
    <dbReference type="OMA" id="IAGHKNE"/>
    <dbReference type="OrthoDB" id="386672at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1344"/>
            <end position="1363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1457" mass="173622" checksum="27972824D0BB73C6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM27</accession>
    <name>A0A1J1GM27_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00119400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526310.1">
        <property type="nucleotide sequence ID" value="XM_028674706.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM27"/>
    <dbReference type="GeneID" id="39729719"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00119400"/>
    <dbReference type="OrthoDB" id="408373at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050228">
        <property type="entry name" value="Carboxylesterase_BioH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43194">
        <property type="entry name" value="HYDROLASE ALPHA/BETA FOLD FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43194:SF2">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN LPX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="2">
        <location>
            <begin position="401"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="734" mass="87003" checksum="D246EDC891B21727" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM97</accession>
    <name>A0A1J1GM97_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Replication factor c protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00107000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526187.1">
        <property type="nucleotide sequence ID" value="XM_028673433.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM97"/>
    <dbReference type="GeneID" id="39729596"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00107000"/>
    <dbReference type="OrthoDB" id="2195431at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23389">
        <property type="entry name" value="CHROMOSOME TRANSMISSION FIDELITY FACTOR 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23389:SF3">
        <property type="entry name" value="CHROMOSOME TRANSMISSION FIDELITY PROTEIN 18 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25361">
        <property type="entry name" value="AAA_lid_RFC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="317"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="198"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="971"/>
            <end position="1028"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1067" mass="127552" checksum="EE25C840F2D37AAB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMN6</accession>
    <name>A0A1J1GMN6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RAP protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00133300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526450.1">
        <property type="nucleotide sequence ID" value="XM_028674861.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMN6"/>
    <dbReference type="GeneID" id="39729858"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00133300"/>
    <dbReference type="OMA" id="ILYHFYV"/>
    <dbReference type="OrthoDB" id="392432at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013584">
        <property type="entry name" value="RAP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08373">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51286">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RAP" evidence="1">
        <location>
            <begin position="1175"/>
            <end position="1237"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1266" mass="151699" checksum="E5EF42CCE27D2082" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMT1</accession>
    <name>A0A1J1GMT1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00138100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526498.1">
        <property type="nucleotide sequence ID" value="XM_028674915.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMT1"/>
    <dbReference type="GeneID" id="39729906"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00138100"/>
    <dbReference type="OMA" id="MCNIFTQ"/>
    <dbReference type="OrthoDB" id="369812at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012317353" description="VWFA domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="1066"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1066" mass="125358" checksum="16CCDC2B580E34D2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMX2</accession>
    <name>A0A1J1GMX2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Dihydroorotate dehydrogenase (quinone), mitochondrial</fullName>
            <ecNumber evidence="5">1.3.5.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PGAL8A_00131800</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>(S)-dihydroorotate + a quinone = orotate + a quinol</text>
            <dbReference type="Rhea" id="RHEA:30187"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:30864"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; orotate from (S)-dihydroorotate (quinone route): step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.2" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526435.1">
        <property type="nucleotide sequence ID" value="XM_028674844.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMX2"/>
    <dbReference type="GeneID" id="39729843"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00131800"/>
    <dbReference type="OMA" id="VYCYSAL"/>
    <dbReference type="OrthoDB" id="14784at2759"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00946"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106430">
        <property type="term" value="F:dihydroorotate dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04738">
        <property type="entry name" value="DHOD_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050074">
        <property type="entry name" value="DHO_dehydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005719">
        <property type="entry name" value="Dihydroorotate_DH_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005720">
        <property type="entry name" value="Dihydroorotate_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001295">
        <property type="entry name" value="Dihydroorotate_DH_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003652">
        <property type="entry name" value="PRK05286.2-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48109:SF4">
        <property type="entry name" value="DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48109">
        <property type="entry name" value="DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01180">
        <property type="entry name" value="DHO_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00911">
        <property type="entry name" value="DHODEHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00912">
        <property type="entry name" value="DHODEHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0288">FMN</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="126"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="Dihydroorotate dehydrogenase catalytic" evidence="14">
        <location>
            <begin position="196"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="343"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG93613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="543" mass="63211" checksum="9CF8F2C6EC179FC3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN07</accession>
    <name>A0A1J1GN07_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA-binding protein mei2 homologue, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00151900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526631.1">
        <property type="nucleotide sequence ID" value="XM_028675062.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN07"/>
    <dbReference type="GeneID" id="39730043"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00151900"/>
    <dbReference type="OMA" id="GTILNIH"/>
    <dbReference type="OrthoDB" id="417481at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12277">
        <property type="entry name" value="RRM3_MEI2_EAR1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007201">
        <property type="entry name" value="Mei2-like_Rrm_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23189">
        <property type="entry name" value="RNA RECOGNITION MOTIF-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04059">
        <property type="entry name" value="RRM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Mei2-like C-terminal RNA recognition motif" evidence="2">
        <location>
            <begin position="251"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="388" mass="45810" checksum="7F732EBC18C511A8" modified="2017-02-15" version="1">MNIQLRDLNLKEDDKKNIKNKRTIHVKNTYISPYVLYNKNYNTDQLKKLNKIFSNENCMVINKNSNFVKENCHEKKILRNEIFNNLCTKSLENRDEEYKLNTNTKMIQMNSEKGYNKDNERIINENNDLLYNLKKINICNYEDDNKSTKIVFKSNELNNYNRITNSDNTSKKNYNIHENTESYFTFPNKTYLEGVTLRNNITCNIKNNVDFNDNYNLRKSSPTDIIYKCEDSIPLGTILNIHNLDSSNHLTTVMLRNIPNKYTQNMLMAVMNEHFKGLYDFFYLPIDFRNKCNVGYAFINFIHPHYAELFIKFFNNYKLNAFKSNKVCSVTWGRVQGLKANIEHYRNSAIMTIPIPQYKPILFQNGIAVSWPESDGPLPAIKLRSQKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN11</accession>
    <name>A0A1J1GN11_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Homologous recombination OB-fold protein OB-fold domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00145400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526570.1">
        <property type="nucleotide sequence ID" value="XM_028674994.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN11"/>
    <dbReference type="GeneID" id="39729978"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00145400"/>
    <dbReference type="OMA" id="NYRIERM"/>
    <dbReference type="OrthoDB" id="21443at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000725">
        <property type="term" value="P:recombinational repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028045">
        <property type="entry name" value="HROB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058570">
        <property type="entry name" value="HROB_OB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14523:SF1">
        <property type="entry name" value="HOMOLOGOUS RECOMBINATION OB-FOLD PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14523">
        <property type="entry name" value="UNCHARACTERIZED PROTEIN C17ORF53 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15072">
        <property type="entry name" value="HROB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homologous recombination OB-fold protein OB-fold" evidence="2">
        <location>
            <begin position="454"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="103"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF15072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="553" mass="64483" checksum="072FE29AB896418A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN47</accession>
    <name>A0A1J1GN47_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00146100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526577.1">
        <property type="nucleotide sequence ID" value="XM_028675003.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN47"/>
    <dbReference type="GeneID" id="39729985"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00146100"/>
    <dbReference type="OMA" id="NECKNFM"/>
    <dbReference type="OrthoDB" id="360590at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="139" mass="16431" checksum="9DB07DCE83848A11" modified="2017-02-15" version="1">MDQSYRKLRTVELQKRKVTQSKNPSNLTERKLGNVYAPKDFDEDSTIVVCNFPQNMTINECKNFMQWIGPVIKVEKISSFMQENNYLVVFCNPYYAKIALEIPLLYENKVKLFTRAVEKRETIWKNINDMISTNINFFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN96</accession>
    <name>A0A1J1GN96_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HVA22-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00165200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526764.1">
        <property type="nucleotide sequence ID" value="XM_028675209.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN96"/>
    <dbReference type="GeneID" id="39730177"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00165200"/>
    <dbReference type="OMA" id="MNYIPFY"/>
    <dbReference type="OrthoDB" id="10009287at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004345">
        <property type="entry name" value="TB2_DP1_HVA22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300">
        <property type="entry name" value="HVA22-LIKE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300:SF117">
        <property type="entry name" value="LP05237P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03134">
        <property type="entry name" value="TB2_DP1_HVA22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU362006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="155" mass="18767" checksum="369986A473324A0A" modified="2017-02-15" version="1">MGLYIIPKKIIHLINIIVCIICPAIKTHNLLLLKKEKINEENLQYIHFLTYWILYSFYSYMESVLIIHFMNYIPFYYEIKLILFFWLYSDTFQGAGYLYFKFIEKNYIILDKKISDLIENKLNKNITSFFNFDKSNNNIHNKIKTTVSKKDLYSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GND2</accession>
    <name>A0A1J1GND2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00148700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526603.1">
        <property type="nucleotide sequence ID" value="XM_028675031.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GND2"/>
    <dbReference type="GeneID" id="39730011"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00148700"/>
    <dbReference type="OMA" id="YIHFSCI"/>
    <dbReference type="OrthoDB" id="392618at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="750" mass="90887" checksum="FD54C2A63CE4AD13" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNF2</accession>
    <name>A0A1J1GNF2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcription factor with AP2 domain(S), putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ApiAP2</name>
        <name evidence="3" type="ORF">PGAL8A_00151400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526627.1">
        <property type="nucleotide sequence ID" value="XM_028675058.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730038"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00151400"/>
    <dbReference type="OrthoDB" id="378691at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1078"/>
            <end position="1154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1652"/>
            <end position="1676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2027"/>
            <end position="2049"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="323"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="498"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="572"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1659"/>
            <end position="1668"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2178" mass="259356" checksum="38744693D6B9F47C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNK8</accession>
    <name>A0A1J1GNK8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Histone-lysine N-methyltransferase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SET6</name>
        <name evidence="7" type="ORF">PGAL8A_00161600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526729.1">
        <property type="nucleotide sequence ID" value="XM_028675171.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNK8"/>
    <dbReference type="GeneID" id="39730141"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00161600"/>
    <dbReference type="OMA" id="QEFKLAY"/>
    <dbReference type="OrthoDB" id="265717at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050869">
        <property type="entry name" value="H3K4_H4K5_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197:SF251">
        <property type="entry name" value="EG:BACR7C10.4 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SET" evidence="5">
        <location>
            <begin position="1"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="62"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="508" mass="60304" checksum="827B671F3C0FBC66" modified="2017-02-15" version="1">MYKIEYKEDRGKCVIAVNQIRAGYCIVESHPEIFIPLCVKYMTPRIIDADNKKNNYKIINICFYCFEKFNKCIYCPNCKYVVYCSEICLERAWKSHREECDIFKSNIFDRYCPSITMRLVINCYLNHFNFYDYCGSITELTKEKYEKFKYPAYIVAVALMSKKKKIFQNFEDNESILKNIIEKFVKISKNTLQIIDNELEPAGLAFYKKPVPYFNHSCLNNCVTIFKNQKLYIRTLMDIYPGEELTISYIDIAFDRNTRLSICLEQYFFTCSCKLCKINIPSECHNIFNTEFICTNSENCKKFLSYMEVVLISELEHKQCYVNKNDFKTYPILKKTNENVWKCMLCKAEVHDNIIKSLLDKEKETVKETIYLETLFNEKYSYDNKSVLQSLNKIKSKIDYLTNFYHHARYSLQKMRAKILYISIQLQEFKLAYNIANQYLKSIEVSYGKFSPIYGYYIFLTGKLALFLDLKSEGLSLIHKAKKNIIKTYGADSPLYRDLEKFLYTNKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPB0</accession>
    <name>A0A1J1GPB0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00082300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525941.1">
        <property type="nucleotide sequence ID" value="XM_028670699.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPB0"/>
    <dbReference type="GeneID" id="39729347"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00082300"/>
    <dbReference type="OrthoDB" id="375885at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="179" mass="21324" checksum="26205636F81731C0" modified="2017-02-15" version="1">MSKKFFGKITEGISPYIWKNNFYSLNLFKSYPPVFSCLSKRCVSTNKIEKKITNNNDKNVMYKSYNDRLKEDITPLNLIKSLPSINHYFNIFDMTKFAIKYVLSYRFFFIYMARTTFQAVRPLMAFCVFGELMKLILATMTSGIFAFFFSFVLAFEVLYFFLQCYISYTFLTMFFDVMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ19</accession>
    <name>A0A1J1GQ19_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">BSD-domain protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00193400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000029">
        <property type="protein sequence ID" value="CRG94536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527351.1">
        <property type="nucleotide sequence ID" value="XM_028670616.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ19"/>
    <dbReference type="GeneID" id="39730459"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00193400"/>
    <dbReference type="OMA" id="KFPWNEI"/>
    <dbReference type="OrthoDB" id="47923at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3970.10">
        <property type="entry name" value="BSD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005607">
        <property type="entry name" value="BSD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035925">
        <property type="entry name" value="BSD_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03909">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00751">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140383">
        <property type="entry name" value="BSD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50858">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BSD" evidence="1">
        <location>
            <begin position="71"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="134" mass="16098" checksum="EB99CE7FF873520D" modified="2017-02-15" version="1">MGNKNTKKYELCEIQYEKEFELKYPWNEIIKWGSNDLNVDVSLTIIKKIIEEIKDITLDEESYFNITEGKSLDEFKFENSFVEWATALLKEITNLKKIRYNIVPKLVNENEFWLRYFATIKIIIIKNIFDTIEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQB3</accession>
    <name>A0A1J1GQB3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00119300</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the UPL family. TOM1/PTR1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000016">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_028674705.1"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:ubiquitin protein ligase activity"/>
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        <property type="project" value="UniProtKB-EC"/>
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        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1750.10:FF:000003">
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    </dbReference>
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        <property type="entry name" value="Probable E3 ubiquitin-protein ligase HECTD2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
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        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
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    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
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    <dbReference type="InterPro" id="IPR050409">
        <property type="entry name" value="E3_ubiq-protein_ligase"/>
    </dbReference>
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        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254:SF67">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HUWE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11254">
        <property type="entry name" value="HECT DOMAIN UBIQUITIN-PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="2187"/>
            <end position="2207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="3916"/>
            <end position="3935"/>
        </location>
    </feature>
    <feature type="domain" description="HECT" evidence="11">
        <location>
            <begin position="7644"/>
            <end position="7979"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="99"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
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            <begin position="2103"/>
            <end position="2123"/>
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    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="2368"/>
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    <feature type="region of interest" description="Disordered" evidence="9">
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            <begin position="2421"/>
            <end position="2451"/>
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    <feature type="region of interest" description="Disordered" evidence="9">
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            <begin position="2661"/>
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    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
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    <feature type="region of interest" description="Disordered" evidence="9">
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            <begin position="3178"/>
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    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="4362"/>
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    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
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    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="4951"/>
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    <feature type="region of interest" description="Disordered" evidence="9">
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    <feature type="region of interest" description="Disordered" evidence="9">
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    <feature type="region of interest" description="Disordered" evidence="9">
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            <begin position="6248"/>
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        <location>
            <begin position="7398"/>
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            <begin position="2303"/>
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            <begin position="102"/>
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            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
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    <sequence length="7979" mass="937834" checksum="71C9C33258A32531" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQB9</accession>
    <name>A0A1J1GQB9_PLAGA</name>
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        <submittedName>
            <fullName evidence="2">Reticulocyte binding protein, putative</fullName>
        </submittedName>
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    <gene>
        <name evidence="2" type="ORF">PGAL8A_00185700</name>
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        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Alveolata</taxon>
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            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
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    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
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    <sequence length="442" mass="52437" checksum="2162464270EF2C79" modified="2017-02-15" version="1">MEKKKILVTFFTFLFIIFGLSYERKLKSNKLKYSINNLQFGVNLDEKENEYNRKIDSVENKVQKKSYLLKNISSVNSENSKVNKRQPYLVYTKKNVPHFDEISDVKEDKKKKNTNSITNFFIQSRSSLSNDANFIDDYKKLNTSVTDHILRAKENYILGLSYVDVGSFYMIKEKKESHEKFRKNHEKTMWDFHKCSLKIVNFYINTKYDMINKLGYLLLVEKDVERYNSYKKELQNIKLKIEEDVKSTENDDINCTKTKDIVYDALGHSINEAYCDASTCNIEKCKNVCCPNKCCYELNCFYTRIFVSYAQIAKKKINKNRDNEFIQEVDNFLNSYESNEIKKSSFNKKSLKNYLDLLIEEVKGIKNDYEEQKKLAYQSYDKFLALEKGAPKMTFSKSNLVNDLAPASIEFKKTFHYADWNEILRDKFYDHKINFYIYFYGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQF9</accession>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
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        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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    <dbReference type="PANTHER" id="PTHR11106">
        <property type="entry name" value="GANGLIOSIDE INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11106:SF27">
        <property type="entry name" value="MACRO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01661">
        <property type="entry name" value="Macro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00506">
        <property type="entry name" value="A1pp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="Macro domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51154">
        <property type="entry name" value="MACRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Macro" evidence="1">
        <location>
            <begin position="85"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="273" mass="32162" checksum="D9D704E9429C80F5" modified="2017-02-15" version="1">MFFFKVYKNDIFHYSFNKIFLRNFKTNKKVNIDKLIKRKKIKSHELYRIEDIELLLQEKNHDVIQEYPTVKNVQKIIDVENLPVFRKDENSNNLLNKIVLHFGDLSYLKGDVAINGTNKIFELMKEGNGYDCSGNFLKICGKFLFEDMKKIREKNKGKKIIITKGYNSAYKSIIHIVEPYYNETAKLKKCYEDILLIAKKNNFKTIIFPLLGSGVSLFKKHDVVICCLEGIYEFLKTKDNFNYIDKIVLCTITDSYWMLLNDSIPLYLDVNIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQI9</accession>
    <name>A0A1J1GQI9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">B-related factor 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00208500</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFIIB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527503.1">
        <property type="nucleotide sequence ID" value="XM_028670785.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQI9"/>
    <dbReference type="GeneID" id="39730612"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00208500"/>
    <dbReference type="OMA" id="ISMVGQF"/>
    <dbReference type="OrthoDB" id="511529at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000126">
        <property type="term" value="C:transcription factor TFIIIB complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097550">
        <property type="term" value="C:transcription preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000995">
        <property type="term" value="F:RNA polymerase III general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001006">
        <property type="term" value="F:RNA polymerase III type 3 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070897">
        <property type="term" value="P:transcription preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20553">
        <property type="entry name" value="CYCLIN_TFIIIB90_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20554">
        <property type="entry name" value="CYCLIN_TFIIIB90_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000002">
        <property type="entry name" value="Transcription factor IIIB 90 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000007">
        <property type="entry name" value="Transcription factor IIIB 90 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.650">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011665">
        <property type="entry name" value="BRF1_TBP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000812">
        <property type="entry name" value="TFIIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013150">
        <property type="entry name" value="TFIIB_cyclin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618:SF4">
        <property type="entry name" value="TRANSCRIPTION FACTOR IIIB 90 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07741">
        <property type="entry name" value="BRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00382">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00685">
        <property type="entry name" value="TIFACTORIIB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0010">Activator</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Cyclin-like" evidence="12">
        <location>
            <begin position="33"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="12">
        <location>
            <begin position="127"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="295"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="697"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="296"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="336"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="701"/>
            <end position="710"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG94688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="759" mass="86794" checksum="25B5B351A65C042F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQM2</accession>
    <name>A0A1J1GQM2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00221200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527630.1">
        <property type="nucleotide sequence ID" value="XM_028670926.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730739"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00221200"/>
    <dbReference type="OrthoDB" id="365750at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1146"/>
            <end position="1189"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1985"/>
            <end position="2039"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2092"/>
            <end position="2155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1156"/>
            <end position="1171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3077" mass="364049" checksum="A90C9C36AC49BD12" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQQ9</accession>
    <name>A0A1J1GQQ9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00219200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527610.1">
        <property type="nucleotide sequence ID" value="XM_028670904.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQQ9"/>
    <dbReference type="GeneID" id="39730719"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00219200"/>
    <dbReference type="OMA" id="FDWHRKI"/>
    <dbReference type="OrthoDB" id="331145at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="193" mass="22945" checksum="8DF0F6E96E861D6B" modified="2017-02-15" version="1">MFNSQGMKRWTMKRFLCFSVGTATIIYATLLVLVSIVMLTHTSHYNVTLFIIISTFNFICAILIFVSVSHKNAFTAYIAYNIVIINYMVEVIEFFICLYNTCTSHSVQWYYENFYWHRKIVYNYNMFYGLLEMIIHLFMFLLSFFVIQLIWSFYRILQVGGNIFSFQTAEHIESVLHGTHYYTYGTIPNVHTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQT5</accession>
    <name>A0A1J1GQT5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00110800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526224.1">
        <property type="nucleotide sequence ID" value="XM_028673843.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQT5"/>
    <dbReference type="GeneID" id="39729633"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00110800"/>
    <dbReference type="OrthoDB" id="382784at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="53" mass="5928" checksum="A11BF93DA6E820C2" modified="2017-02-15" version="1">MSYGCGSVGLPIIRRALIFFLAAETAYVSYELILKPGIPHIYNCLTNKTKKDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQX6</accession>
    <name>A0A1J1GQX6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein eL22</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">60S ribosomal protein L22</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00114800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526264.1">
        <property type="nucleotide sequence ID" value="XM_028674287.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQX6"/>
    <dbReference type="GeneID" id="39729673"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00114800"/>
    <dbReference type="OMA" id="QEDGILN"/>
    <dbReference type="OrthoDB" id="10259820at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.210:FF:000005">
        <property type="entry name" value="60S ribosomal protein L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002671">
        <property type="entry name" value="Ribosomal_eL22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038526">
        <property type="entry name" value="Ribosomal_eL22_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10064">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10064:SF0">
        <property type="entry name" value="FI24544P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01776">
        <property type="entry name" value="Ribosomal_L22e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00041214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="137" mass="16034" checksum="CCFAE5F50CBBC6B6" modified="2017-02-15" version="1">MVAKKGSKITKKLKKKTVKKTNLVKGKKQKVTKSTKGIKYVLDCTKPVKDTILDISGLEQFFKDKIKVDKKTNNLKNKIIVTSDDCKIYITVHIPFSKRYIKYLAKKYLKMHQIRDFLRVIAKGKLAYEFKYFQLNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQY2</accession>
    <name>A0A1J1GQY2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">histone deacetylase</fullName>
            <ecNumber evidence="3">3.5.1.98</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">HDA1</name>
        <name evidence="12" type="ORF">PGAL8A_00231700</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histone deacetylase family. HD type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.98" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527734.1">
        <property type="nucleotide sequence ID" value="XM_028671041.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730844"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00231700"/>
    <dbReference type="OMA" id="NMSRENN"/>
    <dbReference type="OrthoDB" id="424012at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000118">
        <property type="term" value="C:histone deacetylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141221">
        <property type="term" value="F:histone deacetylase activity, hydrolytic mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040029">
        <property type="term" value="P:epigenetic regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF5">
        <property type="entry name" value="HISTONE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0678">Repressor</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="11">
        <location>
            <begin position="889"/>
            <end position="1369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="312"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="313"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG94920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1622" mass="193554" checksum="A97754BA735BDF5D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR53</accession>
    <name>A0A1J1GR53_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Methyltransferase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00214500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527563.1">
        <property type="nucleotide sequence ID" value="XM_028670851.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR53"/>
    <dbReference type="GeneID" id="39730672"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00214500"/>
    <dbReference type="OMA" id="HWAVMDA"/>
    <dbReference type="OrthoDB" id="411785at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000217">
        <property type="entry name" value="Methyltransferase protein 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051419">
        <property type="entry name" value="Lys/N-term_MeTrsfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12176:SF79">
        <property type="entry name" value="METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12176">
        <property type="entry name" value="SAM-DEPENDENT METHYLTRANSFERASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="4">
        <location>
            <begin position="40"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="205" mass="23938" checksum="CB78EDBC8B8477FD" modified="2017-02-15" version="1">MAVYGKISYWNDRYTNEEEQFDWHQRWNGVKHIFTELNIKNDAKILNVGCGTSKFSEEMYDSGYTDITNIDASSVCIKKMKEIYVDKPNLKYILMNVCDMREFKNEEFDLIIDKACLDSIVCSEDSLKNVEEMLSEISRTLKPEGIFIIISHAQPTYRLGYLQKSQYKWDVTVKTVKRPMLGIVAPPVDDSLHYIYICKKENIIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR94</accession>
    <name>A0A1J1GR94_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ubiquitin-activating enzyme, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">UBA1</name>
        <name evidence="6" type="ORF">PGAL8A_00245400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">Protein modification.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ubiquitin-activating E1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527868.1">
        <property type="nucleotide sequence ID" value="XM_028671191.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730982"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00245400"/>
    <dbReference type="OrthoDB" id="10252231at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031510">
        <property type="term" value="C:SUMO activating enzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019948">
        <property type="term" value="F:SUMO activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2660">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, SCCH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.60">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, UFD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038252">
        <property type="entry name" value="UBA_E1_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042063">
        <property type="entry name" value="Ubi_acti_E1_SCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000011">
        <property type="entry name" value="UBQ/SUMO-activ_enz_E1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF4">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1 C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01849">
        <property type="entry name" value="UBIQUITINACT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="5">
        <location>
            <begin position="268"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="5">
        <location>
            <begin position="834"/>
            <end position="1338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="161"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="756"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="176"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="761"/>
            <end position="826"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00043952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1732" mass="206854" checksum="DCC3F00271A75A55" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRA5</accession>
    <name>A0A1J1GRA5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Vacuolar ATP synthase subunit g, putative</fullName>
            <ecNumber evidence="5">3.6.3.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00235100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the V-ATPase G subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.14" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527767.1">
        <property type="nucleotide sequence ID" value="XM_028671078.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRA5"/>
    <dbReference type="GeneID" id="39730879"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00235100"/>
    <dbReference type="OMA" id="PDCTQKS"/>
    <dbReference type="OrthoDB" id="250802at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000221">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005124">
        <property type="entry name" value="V-ATPase_G"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12713:SF11">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12713">
        <property type="entry name" value="VACUOLAR ATP SYNTHASE SUBUNIT G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03179">
        <property type="entry name" value="V-ATPase_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="127" mass="14692" checksum="C2515A9632F70621" modified="2017-02-15" version="1">MAQNKGSNALIQQLLKAEEEADLVIKKAKDVRAKMLKEAETTASEELKIFRAKEKERLNKGHKEKSSAEDEVVTKIEQNTKEEIKKYKELFKKNKDEVAQYIFDKVFTVDLTVPDCTQKSILYKQNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRG1</accession>
    <name>A0A1J1GRG1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Derlin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">DER1-1</name>
        <name evidence="8" type="ORF">PGAL8A_00227900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the derlin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527697.1">
        <property type="nucleotide sequence ID" value="XM_028671001.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRG1"/>
    <dbReference type="GeneID" id="39730806"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00227900"/>
    <dbReference type="OMA" id="FKSQYWR"/>
    <dbReference type="OrthoDB" id="1716531at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007599">
        <property type="entry name" value="DER1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11009">
        <property type="entry name" value="DER1-LIKE PROTEIN, DERLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04511">
        <property type="entry name" value="DER1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="17"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="95"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="140"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="213" mass="24991" checksum="D7AE942046A14E73" modified="2017-02-15" version="1">MVQLGELLSSIPLITRIYLILSSILMVLCSLDVISPLSLYLNWNLVLNDHQYWRLVTCFLYFGSFGLHFFWDAYVLIYYCSSLEDVTFRNNSADFLWMLIVSCLMLLVVSYIFGGVYFYSSCIINVITYVWSKNNSSTRLTIFFFTIKASYLPWVLTLLSLIVDYNSNDNFFGILVGHIYFFFTNVFPLMPISKNTQIFKTPQFLKWLLKQEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRI2</accession>
    <name>A0A1J1GRI2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 5B</fullName>
            <ecNumber evidence="3">3.6.5.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Translation initiation factor IF-2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PGAL8A_00135500</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.3" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526472.1">
        <property type="nucleotide sequence ID" value="XM_028674885.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRI2"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="InterPro"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
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    </dbReference>
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            <end position="565"/>
        </location>
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            <begin position="1"/>
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        <source>
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        <source>
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        <source>
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        <source>
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    <sequence length="935" mass="108154" checksum="4A7397403ACB5298" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRJ4</accession>
    <name>A0A1J1GRJ4_PLAGA</name>
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        <submittedName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00228900</name>
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        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
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            <taxon>Eukaryota</taxon>
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    </organism>
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        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
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                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_028671012.1"/>
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        <source>
            <dbReference type="EMBL" id="CRG94892.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="675" mass="81489" checksum="2E738404B003DF18" modified="2017-02-15" version="1"> </sequence>
</entry>
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    <accession>A0A1J1GRK0</accession>
    <name>A0A1J1GRK0_PLAGA</name>
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        <submittedName>
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    </protein>
    <gene>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_028671045.1"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="219" mass="25437" checksum="F5AF9806518CEF7F" modified="2017-02-15" version="1">MCQCVWELLSIEKSFMKLNDSCGKNSIYKISNNDEFDNFNDSKIVTEKVDYDYTDELSKHSKMIKDKNKLKFKKIMNKFFISDISKYVKAYVKKNDSNIRSEIGITSKKIPISEEERFWTNSYIYNFISHCLLTYNDCKHYIVITGSKNLIQKLTGTGYGYYGVYFTDGKKIGGLGNLFINIKQVRHISFSIMRTLQTKTTSDRSASNNDEACSFIIMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRM2</accession>
    <name>A0A1J1GRM2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00247300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Plasmodiidae</taxon>
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            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
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            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_028671213.1"/>
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    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="203"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="238"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="296"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="330" mass="40406" checksum="8BC2DC313CDE81FD" modified="2017-02-15" version="1">MDKLYGDYDKIVEKYKNNTLYKRRNEKDGNNKREVKEKSNLDKKKEKDLSKKETNKKDKKISDKKLKKENFLLSENSHNKFGNNDSSNENKEHLLKNKRVEHNLRDRSYNQYKIRKKLSIEINKKIFSDSENMHIDDKSFLNDNLPVDINNLIIKKRKNKNGDQKIKQILNKKDKMKFMVNFLYVLYYIFFFFHYIIDLQVNKIYNIVINTFIIIILSVLLCYIHFLKTKNKKLKKIIFYISAYVNLLYCLYIFNTFIYWINVYLNFTLSKKLYLKYRTLYKNVSFIFSYFNFDEIFFFLLIFYGLFFFTSSLLTITLFYYIYNFINYSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRV6</accession>
    <name>A0A1J1GRV6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00264800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528054.1">
        <property type="nucleotide sequence ID" value="XM_028671397.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRV6"/>
    <dbReference type="GeneID" id="39731177"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00264800"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006496">
        <property type="entry name" value="CHP01606_Plasmodium_spp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09688">
        <property type="entry name" value="Wx5_PLAF3D7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="302" mass="36045" checksum="24B42B5804B35D8E" modified="2017-02-15" version="1">MKTLILFLKITTFFLLIWMYQCFYKCYSNKTLVDKNILQTKNKLKYERVLTEGDIAGKKQTYGEECLEKYPLDNKKNKWENPVRYENPYDHWNKVITPFLLEKFNKETSGMDPKWREQKWNNEWNKISANKVNDLSSIFHRSDITEEEKKKLIFPVMGELFSEFRKFIDECKKEMIDNKAESESMKEMIDNKTESESKKEMIGNKTESESKNEMTDNKTESVYKNEMTDNKTESKSKNEMTDNNTESKSKNEMTDNKTESESKKEMIGNKIESESKNEKGKNKTKNKKSNILKFFFKRFDNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSF5</accession>
    <name>A0A1J1GSF5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00264200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528049.1">
        <property type="nucleotide sequence ID" value="XM_028671392.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSF5"/>
    <dbReference type="GeneID" id="39731171"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00264200"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012791738" evidence="2">
        <location>
            <begin position="23"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="392"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="993" mass="113895" checksum="7F2A711825D1B510" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSH7</accession>
    <name>A0A1J1GSH7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00396800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527085.1">
        <property type="nucleotide sequence ID" value="XM_028670321.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSH7"/>
    <dbReference type="GeneID" id="39732498"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00396800"/>
    <dbReference type="OrthoDB" id="2573941at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12411">
        <property type="entry name" value="RRM_ist3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000674">
        <property type="entry name" value="RNA-binding protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051847">
        <property type="entry name" value="RNA_proc/Spliceosome_comp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045844">
        <property type="entry name" value="RRM_Ist3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45880">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN, X-LINKED 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45880:SF1">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN, X-LINKED 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="36"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="297"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="297"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="311"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="370" mass="44020" checksum="94AF77D502CD833C" modified="2017-02-15" version="1">MGIFDKIKSIEKINEAELKNIGQSDSSWHDQYKDSSYIYIGNLDNRLTEGDVIIVFSQYGEPIDINLVRDEETGKSKGYCFLSYADQRSTVLAVDNFNGYKLLDRPLVVDHILNYKLPNKYSSNENENEYKPTGAEGKGIGVYNVIESEINLSKAFEKIDKKCNEEKRRKLLDEDELWALKFEESIKDKYRNIKNENIKKDGLQNDNINKDEPNYNDYIKNESYEYKRKKPSNKYMEEQNIKFDMKIPRKNLYNREDKSKENKKNYECKNKNDHIKKELDKSICVYKRKSEKKENIHINKDISKEKDKYKSKNIKKNRSKDRHKHISKNRSRSKSKDKRKHKSKDKRKHKSKDRRKHKSKDRGSSENIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSN6</accession>
    <name>A0A1J1GSN6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fam-h protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00177100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526880.1">
        <property type="nucleotide sequence ID" value="XM_028670094.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSN6"/>
    <dbReference type="GeneID" id="39730298"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00177100"/>
    <dbReference type="OMA" id="ENDCAIK"/>
    <dbReference type="OrthoDB" id="10561801at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="93"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="232" mass="27141" checksum="B6BA65ACDDA05BC5" modified="2017-02-15" version="1">MNKKNNIFLIPNINKYTGYYSHLDKNFITTYMSTSNINMKKEKRNVLNFLINFFIFILLIWILQCFNNCDSCSLWNNKRDLKSAINVDIKRSLAESKNTTEQISEELKCYKEKDTIEIDLNSRNDQREMEENIEVELKNELETMKDNEKVKRSEGILQFCKGCLKIVSLSIALILSFGSSVLITAERHQSRLNKTYDSANTHPLTILTNLSLMIISIILIHEQVVIKYKKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSS6</accession>
    <name>A0A1J1GSS6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Origin recognition complex subunit 5, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ORC5</name>
        <name evidence="7" type="ORF">PGAL8A_00406400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527181.1">
        <property type="nucleotide sequence ID" value="XM_028670428.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSS6"/>
    <dbReference type="GeneID" id="39732594"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00406400"/>
    <dbReference type="OMA" id="DMCKNIL"/>
    <dbReference type="OrthoDB" id="365981at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005664">
        <property type="term" value="C:nuclear origin of replication recognition complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020796">
        <property type="entry name" value="ORC5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047088">
        <property type="entry name" value="ORC5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048866">
        <property type="entry name" value="ORC5_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12705">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12705:SF0">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14630">
        <property type="entry name" value="ORC5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21639">
        <property type="entry name" value="ORC5_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ORC5 lid" evidence="6">
        <location>
            <begin position="530"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="domain" description="Origin recognition complex subunit 5 C-terminal" evidence="5">
        <location>
            <begin position="622"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="53"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="352"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="87"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="106"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="163"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="360"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF21639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG94360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="812" mass="94673" checksum="F5AFBCFFA3DCB859" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GST8</accession>
    <name>A0A1J1GST8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00271100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000041">
        <property type="protein sequence ID" value="CRG95510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528319.1">
        <property type="nucleotide sequence ID" value="XM_028671692.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GST8"/>
    <dbReference type="GeneID" id="39731242"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00271100"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="732" mass="91086" checksum="EE8F3BF96EEB1718" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSY2</accession>
    <name>A0A1J1GSY2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fusion protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00012900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528171.1">
        <property type="nucleotide sequence ID" value="XM_028671527.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSY2"/>
    <dbReference type="GeneID" id="39728651"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00012900"/>
    <dbReference type="OMA" id="FMKGLEI"/>
    <dbReference type="OrthoDB" id="361131at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="513" mass="62878" checksum="862B19381B3D27D7" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT21</accession>
    <name>A0A1J1GT21_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00389900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527016.1">
        <property type="nucleotide sequence ID" value="XM_028670245.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT21"/>
    <dbReference type="GeneID" id="39732429"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00389900"/>
    <dbReference type="OrthoDB" id="373635at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012633714" description="Thioredoxin domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="197" mass="23972" checksum="80ECC550EFB42D8B" modified="2017-02-15" version="1">MKIFFLFFLCIFLKNVICYIKELSFQEFQKMLTVEKNNQKKNYVLDSSLNYKNVKFFQDYLYIQTNNDFILYIYAKWDTDSNNLITVFREVARVLNENKIKLDFYIFNIDKVKDLCNFLNITTLPLILYVSSIHKKKYNSLLYKVFNSSKDVKISNAFKYNGDMYCYDHIAEWIEAHYYFTKMITRIKYLFYGKNKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT37</accession>
    <name>A0A1J1GT37_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Surface-associated interspersed protein (SURFIN)</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00186000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000024">
        <property type="protein sequence ID" value="CRG94465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527285.1">
        <property type="nucleotide sequence ID" value="XM_028670543.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT37"/>
    <dbReference type="GeneID" id="39730387"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00186000"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="661" mass="77085" checksum="70E6606D061D1B3C" modified="2017-02-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT54</accession>
    <name>A0A1J1GT54_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00286300</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528474.1">
        <property type="nucleotide sequence ID" value="XM_028671863.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731396"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00286300"/>
    <dbReference type="OMA" id="MIVECCH"/>
    <dbReference type="OrthoDB" id="420187at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF758">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="9">
        <location>
            <begin position="811"/>
            <end position="1338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="558"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="573"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="605"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG95666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1389" mass="165288" checksum="6392F409BE8395CC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTH8</accession>
    <name>A0A1J1GTH8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Apicoplast ribosomal protein L15, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00300600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528602.1">
        <property type="nucleotide sequence ID" value="XM_028672006.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTH8"/>
    <dbReference type="GeneID" id="39731539"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00300600"/>
    <dbReference type="OMA" id="DVYWEST"/>
    <dbReference type="OrthoDB" id="361383at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01341">
        <property type="entry name" value="Ribosomal_uL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030878">
        <property type="entry name" value="Ribosomal_uL15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="Ribosomal_uL15/eL18_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005749">
        <property type="entry name" value="Ribosomal_uL15_bac-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934:SF11">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL15M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="Ribosomal proteins L15p and L18e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012498243" evidence="6">
        <location>
            <begin position="17"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="309"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="85"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="319"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="528" mass="62282" checksum="6656BE666E34FB26" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTN7</accession>
    <name>A0A1J1GTN7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Gamete antigen 27/25, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00180000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527232.1">
        <property type="nucleotide sequence ID" value="XM_028670484.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTN7"/>
    <dbReference type="GeneID" id="39730327"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00180000"/>
    <dbReference type="OrthoDB" id="387098at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3030.10">
        <property type="entry name" value="Gametocyte protein Pfg27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015299">
        <property type="entry name" value="Gamete_antigen_PLAspp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036469">
        <property type="entry name" value="Pfg27_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09216">
        <property type="entry name" value="Pfg27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89162">
        <property type="entry name" value="Gametocyte protein Pfg27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="206" mass="24010" checksum="0F0FB686B0B9E889" modified="2017-02-15" version="1">MVGLQENNLVEQGAPKRDDNTNYILAKMDIEFDITVTVRYLDKVKKGKTAEEIRKIIEDHKAIVEEIVETEKHEHTRYKSFLHDDVAYRVADRLSDYCYDEPLTETYCAKIIKAFWIEKDVILKYFKEVLPNKGDLERRLLMSNLTLIKSYVIKEAEAAKIDLSERKLHSISVRLSKFMFFTSALNIIPSKDLPLHPDDDNPPPHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTY5</accession>
    <name>A0A1J1GTY5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00217100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527589.1">
        <property type="nucleotide sequence ID" value="XM_028670881.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTY5"/>
    <dbReference type="GeneID" id="39730698"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00217100"/>
    <dbReference type="OMA" id="DPECNAS"/>
    <dbReference type="OrthoDB" id="372258at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="400"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="412"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="429"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="489"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="642" mass="77999" checksum="5A9EC05A147DE729" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU07</accession>
    <name>A0A1J1GU07_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00219500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527613.1">
        <property type="nucleotide sequence ID" value="XM_028670907.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU07"/>
    <dbReference type="GeneID" id="39730722"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00219500"/>
    <dbReference type="OMA" id="AMNDFHE"/>
    <dbReference type="OrthoDB" id="10251809at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14733">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056737">
        <property type="entry name" value="Beta-prop_ATRN-MKLN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051568">
        <property type="entry name" value="LZTR1/Attractin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46376">
        <property type="entry name" value="LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46376:SF1">
        <property type="entry name" value="LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24981">
        <property type="entry name" value="Beta-prop_ATRN-LZTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="BTB" evidence="3">
        <location>
            <begin position="429"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="593" mass="69545" checksum="FC54355422E70FE8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU23</accession>
    <name>A0A1J1GU23_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein archease-like</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00300500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the archease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528601.1">
        <property type="nucleotide sequence ID" value="XM_028672005.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU23"/>
    <dbReference type="GeneID" id="39731538"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00300500"/>
    <dbReference type="OMA" id="QFYIEAY"/>
    <dbReference type="OrthoDB" id="2190767at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072669">
        <property type="term" value="C:tRNA-splicing ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006388">
        <property type="term" value="P:tRNA splicing, via endonucleolytic cleavage and ligation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.55.10.10:FF:000002">
        <property type="entry name" value="Archease, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.10.10">
        <property type="entry name" value="Archease domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002804">
        <property type="entry name" value="Archease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023572">
        <property type="entry name" value="Archease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036820">
        <property type="entry name" value="Archease_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12682">
        <property type="entry name" value="ARCHEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12682:SF11">
        <property type="entry name" value="PROTEIN ARCHEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01951">
        <property type="entry name" value="Archease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69819">
        <property type="entry name" value="MTH1598-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Archease" evidence="6">
        <location>
            <begin position="57"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00071898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="193" mass="22791" checksum="A50EF99D0184426C" modified="2017-02-15" version="1">MNDSSKKEIISLPQRNRRKINKSFISESEEEEDYVEKNISNNKEKLCENNFKKTYKYEYLDHTADVILHSYGNNLTECFESICISMFNYMCNLNNVKSKIRRNIIVKGDNLDDLLFNFLTEFHFLYGNEYFICNHIDIVKFDKQNFLIEAIGYGDFFNSSKHECGTEIKAITKHELKIISNNENCEIFVLVDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU49</accession>
    <name>A0A1J1GU49_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">SRAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00319600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SOS response-associated peptidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528791.1">
        <property type="nucleotide sequence ID" value="XM_028672217.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU49"/>
    <dbReference type="GeneID" id="39731729"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00319600"/>
    <dbReference type="OMA" id="DCRYTII"/>
    <dbReference type="OrthoDB" id="2111841at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106300">
        <property type="term" value="P:protein-DNA covalent cross-linking repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1680.10">
        <property type="entry name" value="SOS response associated peptidase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003738">
        <property type="entry name" value="SRAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036590">
        <property type="entry name" value="SRAP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13604:SF0">
        <property type="entry name" value="ABASIC SITE PROCESSING PROTEIN HMCES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13604">
        <property type="entry name" value="DC12-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02586">
        <property type="entry name" value="SRAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143081">
        <property type="entry name" value="BB1717-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0190">Covalent protein-DNA linkage</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="152"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="152"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG95983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="325" mass="38447" checksum="40ABD953856F229A" modified="2017-02-15" version="1">MCVRIHYTIDLNVLKRKYNCSKVVNNEKLKKGMINKKNYIPTIFENNENSLEKIYDSQKKNRIIHICIWGINPFNYGKFEKDIALINARLETLHLKKSFKILINKNRCAIIINGYFEWKNDENSSKKIPYYIFNGKSNQKDNEQNSLKKIDNEEIDSKNNEEINQPQNVKNEVEDDEIYSNEEKSQPIEQNSHKRKKITKEVSTKKIKIESSNEECEENESYIILAGLYTVPDDDKKEYRNTVITTSSENTNLKDIHERCPLLLSENSLSLWLNVDNSYSDIIDKIKEEHINACNNLKYMKVQDWNVYSNYSKQEKKESILKYMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU59</accession>
    <name>A0A1J1GU59_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00325800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000053">
        <property type="protein sequence ID" value="CRG96044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528852.1">
        <property type="nucleotide sequence ID" value="XM_028672284.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU59"/>
    <dbReference type="GeneID" id="39731790"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00325800"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="243" mass="28889" checksum="B14E2D30FE727F00" modified="2017-02-15" version="1">MKTLTLYSKITTFLLLIWMYQCFYNCYSYRTWIDENILQTKNELKYERVLTEGNTEEKKQTNAEGCLKERPLDNEKNKCKNPIQYKNPYDPCHGANTPSLSESFDRKAKEMNPKLRDQKLNIECNKISANQVSDLHFISHGPDIPDEEKSKITDSAKNQHDFKLDERLCESNKKMKDNKTEFDSNKELRGNKTESESKKEMTENKAESESKKEQRKKKKKNMKFDLMKHLIFHKFDKIYDDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU69</accession>
    <name>A0A1J1GU69_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00305300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528649.1">
        <property type="nucleotide sequence ID" value="XM_028672058.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731586"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00305300"/>
    <dbReference type="OMA" id="FNIYLEC"/>
    <dbReference type="OrthoDB" id="377029at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="409"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="41"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1516"/>
            <end position="1547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2088" mass="252178" checksum="C0631A7859941B2B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUB6</accession>
    <name>A0A1J1GUB6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">WD repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00331800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528908.1">
        <property type="nucleotide sequence ID" value="XM_028672347.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUB6"/>
    <dbReference type="GeneID" id="39731848"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00331800"/>
    <dbReference type="OMA" id="WDQTVKC"/>
    <dbReference type="OrthoDB" id="308449at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF8">
        <property type="entry name" value="F-BOX AND WD REPEAT DOMAIN CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="37"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="249"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="508"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="547" mass="63812" checksum="E4175D2037233A22" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUK7</accession>
    <name>A0A1J1GUK7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">GTP-binding nuclear protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00344300</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the small GTPase superfamily. Ran family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529030.1">
        <property type="nucleotide sequence ID" value="XM_028672482.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUK7"/>
    <dbReference type="GeneID" id="39731973"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00344300"/>
    <dbReference type="OMA" id="FNAWDTA"/>
    <dbReference type="OrthoDB" id="48625at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000054">
        <property type="term" value="P:ribosomal subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00877">
        <property type="entry name" value="Ran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001228">
        <property type="entry name" value="GTP-binding nuclear protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002041">
        <property type="entry name" value="Ran_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24071:SF0">
        <property type="entry name" value="GTP-BINDING NUCLEAR PROTEIN RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24071">
        <property type="entry name" value="RAN GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00627">
        <property type="entry name" value="GTPRANTC4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51418">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG96225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="214" mass="24829" checksum="5FD96D4625E7A6EC" modified="2017-02-15" version="1">MDAQEFIPQYKLILVGDGGVGKTTFVKRHLTGEFEKKYIPTLGVEVHPLKFQTNFGKTQFNVWDTAGQEKFGGLRDGYYIKSDCAIIMFDVSSRITYKNVPNWYRDITRVCETIPMVLVGNKVDVKDRQVKSRQIQFHRKRNLQYYDLSARSNYNFEKPFLWLARRLSNQPNLVFVGEHAKAPEFQIDLNVVREAEKELEQAAAVAIDEEDIEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUR9</accession>
    <name>A0A1J1GUR9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Neutral-sphingomyelinase activation factor protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00350700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529094.1">
        <property type="nucleotide sequence ID" value="XM_028672553.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732037"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00350700"/>
    <dbReference type="OMA" id="TYMHTIL"/>
    <dbReference type="OrthoDB" id="26681at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06071">
        <property type="entry name" value="Beach"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1540.10">
        <property type="entry name" value="BEACH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000409">
        <property type="entry name" value="BEACH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036372">
        <property type="entry name" value="BEACH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050865">
        <property type="entry name" value="BEACH_Domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057496">
        <property type="entry name" value="FAN-like_PH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023362">
        <property type="entry name" value="PH-BEACH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13743">
        <property type="entry name" value="BEIGE/BEACH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13743:SF123">
        <property type="entry name" value="PROTEIN FAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02138">
        <property type="entry name" value="Beach"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25400">
        <property type="entry name" value="PH_FAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01026">
        <property type="entry name" value="Beach"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81837">
        <property type="entry name" value="BEACH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50197">
        <property type="entry name" value="BEACH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51783">
        <property type="entry name" value="PH_BEACH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BEACH-type PH" evidence="3">
        <location>
            <begin position="292"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="BEACH" evidence="2">
        <location>
            <begin position="399"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="742"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="742"/>
            <end position="751"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1291" mass="153860" checksum="09A39E0EF3BD70A9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUT4</accession>
    <name>A0A1J1GUT4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00352300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529110.1">
        <property type="nucleotide sequence ID" value="XM_028672571.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUT4"/>
    <dbReference type="GeneID" id="39732053"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00352300"/>
    <dbReference type="OMA" id="VCKAHTP"/>
    <dbReference type="OrthoDB" id="425567at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="82" mass="10073" checksum="545D3F7253BF1290" modified="2017-02-15" version="1">MVFIPVEVIFKKFPNFSKDRVKFLRRYSFLSLFLGGLFVYKAHKPDFSIRHYNPSYFYKRHLDKLKKKGLINEEKYNKYLDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUY9</accession>
    <name>A0A1J1GUY9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CFAP65-like ninth Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00349200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529079.1">
        <property type="nucleotide sequence ID" value="XM_028672537.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732022"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00349200"/>
    <dbReference type="OMA" id="FFKRHYF"/>
    <dbReference type="OrthoDB" id="415597at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031514">
        <property type="term" value="C:motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052614">
        <property type="entry name" value="CFAP65"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056344">
        <property type="entry name" value="Ig_CFAP65-like_9th"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46127">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46127:SF1">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24816">
        <property type="entry name" value="Ig_CFAP65__9th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CFAP65-like ninth Ig-like" evidence="1">
        <location>
            <begin position="1059"/>
            <end position="1240"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1800" mass="214148" checksum="CF1EA3F2EF1F79F7" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV16</accession>
    <name>A0A1J1GV16_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chloroquine resistance marker protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00254900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527957.1">
        <property type="nucleotide sequence ID" value="XM_028671290.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731077"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00254900"/>
    <dbReference type="OMA" id="IYLRYDN"/>
    <dbReference type="OrthoDB" id="428159at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045053">
        <property type="term" value="P:protein retention in Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026847">
        <property type="entry name" value="VPS13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16166:SF93">
        <property type="entry name" value="INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16166">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="410"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1556"/>
            <end position="1576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1795"/>
            <end position="1818"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="2868"/>
            <end position="2921"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="3594"/>
            <end position="3623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="4797"/>
            <end position="4895"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="5110"/>
            <end position="5132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="6444"/>
            <end position="6482"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="810"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="5371"/>
            <end position="5398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="332"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="418"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="2868"/>
            <end position="2912"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="4802"/>
            <end position="4822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="4823"/>
            <end position="4895"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="5110"/>
            <end position="5131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="6444"/>
            <end position="6476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="6716" mass="798056" checksum="32DE2BBE0BC83CAC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVJ1</accession>
    <name>A0A1J1GVJ1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">WD domain, G-beta repeat-containing protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00348000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529067.1">
        <property type="nucleotide sequence ID" value="XM_028672523.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVJ1"/>
    <dbReference type="GeneID" id="39732010"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00348000"/>
    <dbReference type="OMA" id="TKTFNTC"/>
    <dbReference type="OrthoDB" id="256303at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF0">
        <property type="entry name" value="NOTCHLESS PROTEIN HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="46"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="166"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="543" mass="62591" checksum="642E3820FA14DD29" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVP6</accession>
    <name>A0A1J1GVP6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00354400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529131.1">
        <property type="nucleotide sequence ID" value="XM_028672594.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVP6"/>
    <dbReference type="GeneID" id="39732074"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00354400"/>
    <dbReference type="OMA" id="DECISMK"/>
    <dbReference type="OrthoDB" id="387530at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="329"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="365" mass="42853" checksum="C54EECC1459D2E4A" modified="2017-02-15" version="1">MKKMNEENLKGINNKENVNQNKPREIVNSYNDITDIAVVSGVSNKNEEYICNINKENENVVIDNSYTKHKNEGIINIENNSNDNISTSIINKSIRIINDSIYNIKNNLTSIKNIINLNEESEEETISENYKSDESSIVKTFENLKDDEYLDSKNNEDLELLLKTVINTKKEEKQFTTLDIIDECISIGNIYSINKSKQLLNKDNNSVIKNENLTNEKKSSFENSEVDDNYVEDINLDNLDNLDKFLKINKVKSYNEYGIESTSNCSLNTSNFQTEQKKNTKNKSGNLYKDTLYKFKDFLQNEENKLTYLLKKFLKKKKLNMLLKDKKKICYFILHLFFFFSYAFFAIFFIFLKRIFYHIIFDQDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVQ5</accession>
    <name>A0A1J1GVQ5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cyclin-dependent kinase 2 homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Cell division control protein 2 homolog</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">cdc2-related kinase 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00249900</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">May form a complex composed of at least the catalytic subunit CRK2 and a cyclin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527912.1">
        <property type="nucleotide sequence ID" value="XM_028671240.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVQ5"/>
    <dbReference type="GeneID" id="39731027"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00249900"/>
    <dbReference type="OMA" id="KLWWSIK"/>
    <dbReference type="OrthoDB" id="10264738at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="412"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="444"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00039612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00041902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00042858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG95099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="858" mass="102385" checksum="70EFE50F50C66A10" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVU4</accession>
    <name>A0A1J1GVU4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CDT1 Geminin-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00254400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527952.1">
        <property type="nucleotide sequence ID" value="XM_028671284.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVU4"/>
    <dbReference type="GeneID" id="39731072"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00254400"/>
    <dbReference type="OMA" id="CIISEHE"/>
    <dbReference type="OrthoDB" id="369923at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014939">
        <property type="entry name" value="CDT1_Gemini-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08839">
        <property type="entry name" value="CDT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CDT1 Geminin-binding" evidence="3">
        <location>
            <begin position="426"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="337"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="795"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="83"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="346"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="852" mass="99827" checksum="B169468296B7A81B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVV6</accession>
    <name>A0A1J1GVV6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">High molecular weight rhoptry protein 3, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00417900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529402.1">
        <property type="nucleotide sequence ID" value="XM_028672895.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVV6"/>
    <dbReference type="GeneID" id="39732710"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00417900"/>
    <dbReference type="OMA" id="GEPEQFY"/>
    <dbReference type="OrthoDB" id="392048at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054451">
        <property type="entry name" value="RhopH3_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22808">
        <property type="entry name" value="RhopH3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013380396" evidence="2">
        <location>
            <begin position="21"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="domain" description="RhopH3 C-terminal" evidence="3">
        <location>
            <begin position="360"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="794"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="812"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="843"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="871"/>
            <end position="886"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="915" mass="107373" checksum="C5ADB42F44CE3D6B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW75</accession>
    <name>A0A1J1GW75_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Selenoprotein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">Sel1</name>
        <name evidence="1" type="ORF">PGAL8A_00275400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528365.1">
        <property type="nucleotide sequence ID" value="XM_028671742.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW75"/>
    <dbReference type="GeneID" id="39731286"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00275400"/>
    <dbReference type="OMA" id="CNNEFEK"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="58" mass="7230" checksum="09EA33092A529C08" modified="2017-02-15" version="1" fragment="single">MNYEKEKECNNEFEKIFKDRKLKHEHLRRKNSKHNKFILPLLNLIKKIINFLKTTFNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWC5</accession>
    <name>A0A1J1GWC5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphodiesterase</fullName>
            <ecNumber evidence="6">3.1.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00280200</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="6">Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cyclic nucleotide phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.-" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528413.1">
        <property type="nucleotide sequence ID" value="XM_028671796.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWC5"/>
    <dbReference type="GeneID" id="39731335"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00280200"/>
    <dbReference type="OrthoDB" id="342865at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004114">
        <property type="term" value="F:3',5'-cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1300.10">
        <property type="entry name" value="3'5'-cyclic nucleotide phosphodiesterase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023088">
        <property type="entry name" value="PDEase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002073">
        <property type="entry name" value="PDEase_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036971">
        <property type="entry name" value="PDEase_catalytic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023174">
        <property type="entry name" value="PDEase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11347">
        <property type="entry name" value="CYCLIC NUCLEOTIDE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00233">
        <property type="entry name" value="PDEase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00387">
        <property type="entry name" value="PDIESTERASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00126">
        <property type="entry name" value="PDEASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51845">
        <property type="entry name" value="PDEASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="111"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="264"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="PDEase" evidence="8">
        <location>
            <begin position="489"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="571"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="571"/>
            <end position="575"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="575"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="611"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="612"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="612"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="612"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="724"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="724"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="776"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG95605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="909" mass="106650" checksum="41C117E1EFA1845D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWF2</accession>
    <name>A0A1J1GWF2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FHA domain protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00422500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529449.1">
        <property type="nucleotide sequence ID" value="XM_028672947.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWF2"/>
    <dbReference type="GeneID" id="39732757"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00422500"/>
    <dbReference type="OMA" id="FHAMIKF"/>
    <dbReference type="OrthoDB" id="264354at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16495">
        <property type="entry name" value="RING_CH-C4HC3_MARCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46210">
        <property type="entry name" value="FHA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46210:SF1">
        <property type="entry name" value="FHA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-CH-type" evidence="6">
        <location>
            <begin position="718"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="5">
        <location>
            <begin position="838"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="388"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="665"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="998"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1221"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="388"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="665"/>
            <end position="682"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1244" mass="143977" checksum="0E1EAF01D277ADBF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWS4</accession>
    <name>A0A1J1GWS4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RIIa domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00296900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528565.1">
        <property type="nucleotide sequence ID" value="XM_028671964.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWS4"/>
    <dbReference type="GeneID" id="39731502"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00296900"/>
    <dbReference type="OMA" id="QKIEPSY"/>
    <dbReference type="OrthoDB" id="10249338at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22971">
        <property type="entry name" value="DD_RIIAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059162">
        <property type="entry name" value="RIIAD1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47391">
        <property type="entry name" value="Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="169" mass="20382" checksum="2AE406AC32836AE0" modified="2017-02-15" version="1">MQRLNSLENNSRNFYEDTSKNILKNDTDKNINILPSLNENTFSSFNFEKIGENDYFLTNNLNDSVYDKPENIVFKKDFDREKFEKKKIFLFNLSEEQKEEAKNLKINKILQNEMYLKKNKVLKYIIQIFLSDILKEKPDNIYEYTADYFTQPNLKQYILQKLKQMLNKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX36</accession>
    <name>A0A1J1GX36_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcription elongation factor Spt6 helix-hairpin-helix motif domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00278100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528392.1">
        <property type="nucleotide sequence ID" value="XM_028671773.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731314"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00278100"/>
    <dbReference type="OMA" id="LDNEWIN"/>
    <dbReference type="OrthoDB" id="343921at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008023">
        <property type="term" value="C:transcription elongation factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034728">
        <property type="term" value="P:nucleosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140673">
        <property type="term" value="P:transcription elongation-coupled chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.10">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.850">
        <property type="entry name" value="Spt6, helix-hairpin-helix domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.140">
        <property type="entry name" value="YqgF/RNase H-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036860">
        <property type="entry name" value="SH2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028083">
        <property type="entry name" value="Spt6_acidic_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032706">
        <property type="entry name" value="Spt6_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017072">
        <property type="entry name" value="TF_Spt6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037027">
        <property type="entry name" value="YqgF/RNaseH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10145">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR SPT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10145:SF6">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR SPT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14635">
        <property type="entry name" value="HHH_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14632">
        <property type="entry name" value="SPT6_acidic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Spt6 acidic N-terminal" evidence="3">
        <location>
            <begin position="272"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription elongation factor Spt6 helix-hairpin-helix motif" evidence="4">
        <location>
            <begin position="1881"/>
            <end position="1984"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="93"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="148"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="453"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="506"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1536"/>
            <end position="1622"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1662"/>
            <end position="1681"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1076"/>
            <end position="1104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="102"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="149"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="188"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="264"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="297"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="462"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="508"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="526"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1548"/>
            <end position="1557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1558"/>
            <end position="1582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1599"/>
            <end position="1609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1610"/>
            <end position="1620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1667"/>
            <end position="1681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2554" mass="307323" checksum="E88ACDE681EFF33A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX50</accession>
    <name>A0A1J1GX50_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial-processing peptidase subunit beta, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">MAS1</name>
        <name evidence="12" type="ORF">PGAL8A_00446700</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the peptidase M16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529689.1">
        <property type="nucleotide sequence ID" value="XM_028673214.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX50"/>
    <dbReference type="GeneID" id="39733000"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00446700"/>
    <dbReference type="OMA" id="IDVVCDM"/>
    <dbReference type="OrthoDB" id="10251424at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000008">
        <property type="entry name" value="Mitochondrial-processing peptidase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.830.10:FF:000044">
        <property type="entry name" value="Mitochondrial-processing peptidase subunit beta, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050361">
        <property type="entry name" value="MPP/UQCRC_Complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001431">
        <property type="entry name" value="Pept_M16_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851:SF149">
        <property type="entry name" value="GH01077P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851">
        <property type="entry name" value="METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00143">
        <property type="entry name" value="INSULINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M16 N-terminal" evidence="10">
        <location>
            <begin position="49"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="11">
        <location>
            <begin position="201"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG96886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="477" mass="54872" checksum="EA5866068BB00A4A" modified="2017-02-15" version="1">MFKKKVQNILSVINKKNIFSRNYNSYNLAQEIINQPITRISELSNKLKIATVKNNCEIPTIGIWISSGSKYENKFNNGVAHFLEHMIFKGTKKRNRIQLEKEIENMGAHLNAYTAREQTGYYCKCFKEDVKWCIELLSDILTNSVFDENLIEMEKHVILREMEEVEKSKDEVIFDKLHMTAFRDHPLGYTILGPVENIKNMKRQDIIKYIQKNYTSDRMVLCAVGDVDHEEIVKLAEKNFSHLKPQPKSILKSLDEKPFFCGSEIIVRDDDSGPNAHVAVAFEGVEWKSPDSITFMLMQCIIGSYKKNEEGVLPGKLSANRTVNNICNKMTVGCADYFTSFNTCYNNTGLFGFYVQCDEIAVEHALGELMFGITSLSYSITDEEVELAKIQLKTQLISMFESSSTLAEEVSRQILVYGRKITLAEFILRLNEIDTEEVKRVAWKYLHDRDIAVAAIGALHGMPQYTDLRQKTYWLRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX53</accession>
    <name>A0A1J1GX53_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosomal RNA-processing protein 14/surfeit locus protein 6 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00441300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529635.1">
        <property type="nucleotide sequence ID" value="XM_028673153.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX53"/>
    <dbReference type="GeneID" id="39732946"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00441300"/>
    <dbReference type="OMA" id="KSRKRWA"/>
    <dbReference type="OrthoDB" id="378879at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029190">
        <property type="entry name" value="Rrp14/SURF6_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04935">
        <property type="entry name" value="SURF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal RNA-processing protein 14/surfeit locus protein 6 C-terminal" evidence="2">
        <location>
            <begin position="43"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="132" mass="15773" checksum="CCA26389527CE7FB" modified="2017-02-15" version="1">MTKKKNKSRNYIRSIKKDQKCLTINKANNDISDDLIIGNIPNLNENKKKKNLPKIVQIKKNFKKIKKEKELLSNLDTEQKEKAEHLLKVKKAILKSKGEKVYDEKSLKKRKKNIFKRKEKSRKRWENKTKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX90</accession>
    <name>A0A1J1GX90_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UBA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00444500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529667.1">
        <property type="nucleotide sequence ID" value="XM_028673189.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX90"/>
    <dbReference type="GeneID" id="39732978"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00444500"/>
    <dbReference type="OMA" id="CANAKDH"/>
    <dbReference type="OrthoDB" id="336240at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036339">
        <property type="entry name" value="PUB-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018997">
        <property type="entry name" value="PUB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46713">
        <property type="entry name" value="F13M7.16 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46713:SF1">
        <property type="entry name" value="F13M7.16 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09409">
        <property type="entry name" value="PUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00580">
        <property type="entry name" value="PUG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143503">
        <property type="entry name" value="PUG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBA" evidence="3">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="44"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="95"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="44"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="65"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="304" mass="36432" checksum="1D934DC8D5AF9EF1" modified="2017-02-15" version="1">MDEQNKLIEQMQELGYSRELSVKVIKKSGAKTIDEILNWIELTEENEDYNNSEVEDTSQNDVNEKSMNNSDNMNKDNLGSTTENKTKLSPEEVQKKALELQKKIREKKLIKEKEEELQKEKNRIAMAKEIQKRREQLEEYERKKYIETLEREKNEHKKEKQKQLELLKREYEAKFGIEYKHEEVKKSINELTENERREEIAILLNSLKNKNKDKKKELISSLNILKTYFGNIKDNILEKKYQRIKKENKIFVEKIKIYEEMLKIFLLVGFEDTGEFYVIKNYPNTYLLSSAMKFIDLIIKTLNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXC4</accession>
    <name>A0A1J1GXC4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Vacuolar ATP synthase subunit e, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00447700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the V-ATPase E subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529699.1">
        <property type="nucleotide sequence ID" value="XM_028673225.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXC4"/>
    <dbReference type="GeneID" id="39733010"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00447700"/>
    <dbReference type="OMA" id="QHMMAFI"/>
    <dbReference type="OrthoDB" id="10263003at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033178">
        <property type="term" value="C:proton-transporting two-sector ATPase complex, catalytic domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2320.30">
        <property type="entry name" value="ATP synthase, E subunit, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00311">
        <property type="entry name" value="ATP_synth_E_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038495">
        <property type="entry name" value="ATPase_E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002842">
        <property type="entry name" value="ATPase_V1_Esu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45715">
        <property type="entry name" value="ATPASE H+-TRANSPORTING V1 SUBUNIT E1A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01991">
        <property type="entry name" value="vATP-synt_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160527">
        <property type="entry name" value="V-type ATPase subunit E-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="235" mass="27287" checksum="48F19B5861A5DC52" modified="2017-02-15" version="1">MALDDAEAQKQIQQMVNFILNEAKDKAHEIEAKALEDFNIEKLRIVQKMKEKIRVEFQKKAKQMEIKRSISRSSAINKARLKKMCAKDQVFKEIYKISSEKLNELYKDKDKYKNLIVDLIVQSLFYIQEPHVIVRCRDIDKSIVESCLNEAVQKYTDQLKKQLNVVKTIKIEIDKSGDYLPPPPSKDNEGNSCLGGVILTTPNRKINCDNTLDVRLKLAIEYCTPEIKKMFFQKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXE2</accession>
    <name>A0A1J1GXE2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00473400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529954.1">
        <property type="nucleotide sequence ID" value="XM_028673508.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXE2"/>
    <dbReference type="GeneID" id="39733267"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00473400"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="310"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="443"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="499"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="384"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="316"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="329"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="443"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="506"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="572" mass="69418" checksum="EDCCB4293B2E14B1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXF7</accession>
    <name>A0A1J1GXF7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fam-i protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00474600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000092">
        <property type="protein sequence ID" value="CRG97167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529970.1">
        <property type="nucleotide sequence ID" value="XM_028673526.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXF7"/>
    <dbReference type="GeneID" id="39733279"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00474600"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="121"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="235" mass="27844" checksum="46F47CE50C9F3166" modified="2017-02-15" version="1">MDPNLSDAINNDSNKRLNEGDSTTGFAHRAINDATVSIPENPLHHNLNSRDAIQNPSKDISLDSATPTNLLDKKSLSIFQLVIIIISFLRFKRIYSLKLKAKNEMNVRLQKILHNSNKRIKGDLEKEMQKEKNKMKEDQEKLLKKKKKIEVEEKRVLREKEKWEKKTLKEKELCGQDMLKQLEEWEKRIINKGEVWKKRILNEKIILDKKMRKNKEEGEKKMLEIIKKFEKEMLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXK8</accession>
    <name>A0A1J1GXK8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00323400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000050">
        <property type="protein sequence ID" value="CRG96021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528829.1">
        <property type="nucleotide sequence ID" value="XM_028672259.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731767"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00323400"/>
    <dbReference type="OMA" id="PENNEER"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="677"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="220"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="387"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="639"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="709"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1543"/>
            <end position="1592"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1130"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1347"/>
            <end position="1374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="220"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="247"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="273"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="387"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="644"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="713"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1552"/>
            <end position="1580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1581"/>
            <end position="1592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1592" mass="186577" checksum="6E09CDE78D1897A7" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXM4</accession>
    <name>A0A1J1GXM4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00325000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000052">
        <property type="protein sequence ID" value="CRG96037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528845.1">
        <property type="nucleotide sequence ID" value="XM_028672276.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731783"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00325000"/>
    <dbReference type="OrthoDB" id="348930at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="326"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="462"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="334"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="346"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="462"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="500"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1715" mass="203007" checksum="ACE6B38586CF1083" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXP7</accession>
    <name>A0A1J1GXP7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Reticulocyte binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00411400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000055">
        <property type="protein sequence ID" value="CRG96064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528869.1">
        <property type="nucleotide sequence ID" value="XM_028672303.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXP7"/>
    <dbReference type="GeneID" id="39732644"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00411400"/>
    <dbReference type="OMA" id="PYHARVY"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009618943" evidence="2">
        <location>
            <begin position="24"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="224"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="572"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="793" mass="93552" checksum="5E0DD8B8DFE5AFD0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXW4</accession>
    <name>A0A1J1GXW4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Dipeptidyl peptidase 1</fullName>
            <ecNumber evidence="6">3.4.14.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Cathepsin C</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Cathepsin J</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">Dipeptidyl peptidase I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15">Dipeptidyl transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="primary">DPAP2</name>
        <name evidence="20" type="ORF">PGAL8A_00468500</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Thiol protease. Has dipeptidylpeptidase activity. Active against a broad range of dipeptide substrates composed of both polar and hydrophobic amino acids. Proline cannot occupy the P1 position and arginine cannot occupy the P2 position of the substrate. Can act as both an exopeptidase and endopeptidase. Activates serine proteases such as elastase, cathepsin G and granzymes A and B.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, except when Xaa is Arg or Lys, or Yaa or Zaa is Pro.</text>
            <dbReference type="EC" id="3.4.14.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>chloride</name>
            <dbReference type="ChEBI" id="CHEBI:17996"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Tetramer of heterotrimers consisting of exclusion domain, heavy- and light chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase C1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.14.1" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529907.1">
        <property type="nucleotide sequence ID" value="XM_028673457.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXW4"/>
    <dbReference type="GeneID" id="39733218"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00468500"/>
    <dbReference type="OMA" id="NAVQKSW"/>
    <dbReference type="OrthoDB" id="640249at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.80">
        <property type="entry name" value="Cathepsin C, exclusion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014882">
        <property type="entry name" value="CathepsinC_exc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036496">
        <property type="entry name" value="CathepsinC_exc_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025661">
        <property type="entry name" value="Pept_asp_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000169">
        <property type="entry name" value="Pept_cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025660">
        <property type="entry name" value="Pept_his_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013128">
        <property type="entry name" value="Peptidase_C1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000668">
        <property type="entry name" value="Peptidase_C1A_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12411">
        <property type="entry name" value="CYSTEINE PROTEASE FAMILY C1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08773">
        <property type="entry name" value="CathepsinC_exc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00112">
        <property type="entry name" value="Peptidase_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00645">
        <property type="entry name" value="Pept_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75001">
        <property type="entry name" value="Dipeptidyl peptidase I (cathepsin C), exclusion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00640">
        <property type="entry name" value="THIOL_PROTEASE_ASN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00139">
        <property type="entry name" value="THIOL_PROTEASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00639">
        <property type="entry name" value="THIOL_PROTEASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="20" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="12" id="KW-0868">Chloride</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="20" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="20" id="KW-0645">Protease</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="18" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="18">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5018591105" description="Dipeptidyl peptidase 1" evidence="18">
        <location>
            <begin position="20"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C1A papain C-terminal" evidence="19">
        <location>
            <begin position="294"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00014709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00030778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00032961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00045556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="SMART" id="SM00645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="CRG97104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="567" mass="66734" checksum="907BADBBEFD66318" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXZ5</accession>
    <name>A0A1J1GXZ5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00337000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528957.1">
        <property type="nucleotide sequence ID" value="XM_028672401.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXZ5"/>
    <dbReference type="GeneID" id="39731900"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00337000"/>
    <dbReference type="OMA" id="EWGIYQM"/>
    <dbReference type="OrthoDB" id="391581at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="82" mass="10112" checksum="ACD5AD490054AF17" modified="2017-02-15" version="1">MKSGLWEKGVKFSFGILGIIYFLYLKRFVIQEWEIYQTKKKERDINTNKIEINECSENVRDILEEEKKNKKYKKKFNYHKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY13</accession>
    <name>A0A1J1GY13_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HSP20-like chaperone, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00310800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528704.1">
        <property type="nucleotide sequence ID" value="XM_028672119.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY13"/>
    <dbReference type="GeneID" id="39731641"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00310800"/>
    <dbReference type="OMA" id="ITYNPRI"/>
    <dbReference type="OrthoDB" id="1431247at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06464">
        <property type="entry name" value="ACD_sHsps-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031107">
        <property type="entry name" value="Small_HSP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11527">
        <property type="entry name" value="HEAT-SHOCK PROTEIN 20 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="SHSP" evidence="4">
        <location>
            <begin position="111"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="230" mass="26400" checksum="30805046C2885C3E" modified="2017-02-15" version="1">MVLLNATKPKIIIESSGIPIMQESIPGILSSPVEKTVYSSYAYNVPVSQPKVISHNEYKYNSTKYTTKSHNMQKPEFINTFEPHNGFYYEGIPLKTNTNNIFEITPSQEELNKITYNPRIEIYSTSAFAVVMMDIPGTSKENLNVELEKGLLKIYGRKNKPKIEELEKENEYHTKIIERLNEYYFCKIFQMPPAFSEGQSISCKLNDGELVIKILANELKTQKKVIDIQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY18</accession>
    <name>A0A1J1GY18_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidylprolyl isomerase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00493600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530159.1">
        <property type="nucleotide sequence ID" value="XM_028673736.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY18"/>
    <dbReference type="GeneID" id="39733469"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00493600"/>
    <dbReference type="OMA" id="YQFGYAQ"/>
    <dbReference type="OrthoDB" id="1902587at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012339677" description="Peptidylprolyl isomerase" evidence="1">
        <location>
            <begin position="21"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="139" mass="15954" checksum="46B622F735E10A39" modified="2017-02-15" version="1">MIKVSFILFLVFCLLIIVKSDKETYIPLSNYEIINKFSVRVLKESSIKCGLETNDEAEIEMRTFSPGVSIMPQILSDYQFGYANQKFIVGEHNIDPLNKGLRGMCVGELRLSILIGDMGKIYYEITLKDYKKNVRNTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY44</accession>
    <name>A0A1J1GY44_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Apicoplast ribosomal protein L29, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00314100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528736.1">
        <property type="nucleotide sequence ID" value="XM_028672155.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY44"/>
    <dbReference type="GeneID" id="39731674"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00314100"/>
    <dbReference type="OMA" id="TIYYERY"/>
    <dbReference type="OrthoDB" id="382438at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036049">
        <property type="entry name" value="Ribosomal_uL29_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46561">
        <property type="entry name" value="Ribosomal protein L29 (L29p)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="116" mass="14298" checksum="2273DF2E997A759B" modified="2017-02-15" version="1">MFFLCNTYLIKGVKTKRKYELYLNYKISIINNKKNINRLNCYKKKVKAKELRKLSTEDLEKEITKCRLDIQMFQQKGFYDIHNFNIHYEKNARRKLAQLLTIYYERYLDNNIRIKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY98</accession>
    <name>A0A1J1GY98_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA-directed RNA polymerase 2, putative</fullName>
            <ecNumber evidence="7">2.7.7.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00501000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530238.1">
        <property type="nucleotide sequence ID" value="XM_028673824.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY98"/>
    <dbReference type="GeneID" id="39733543"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00501000"/>
    <dbReference type="OMA" id="MPHPLEN"/>
    <dbReference type="OrthoDB" id="10248581at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06926">
        <property type="entry name" value="RNAP_II_RPB11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="entry name" value="RNA polymerase, RBP11-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00261">
        <property type="entry name" value="RNApol_arch_Rpo11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037685">
        <property type="entry name" value="RBP11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009025">
        <property type="entry name" value="RBP11-like_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008193">
        <property type="entry name" value="RNA_pol_Rpb11_13-16kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022905">
        <property type="entry name" value="Rpo11-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13946">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I,II,III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13946:SF16">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13656">
        <property type="entry name" value="RNA_pol_L_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="RBP11-like subunits of RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01154">
        <property type="entry name" value="RNA_POL_L_13KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase RBP11-like dimerisation" evidence="6">
        <location>
            <begin position="37"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="126" mass="14351" checksum="3D6CC050817097BE" modified="2017-02-15" version="1">MSVPTLSNKPENIDLLVLGPGEKKVKCIISERGDCNIFIIKLEDHTLGNLIKQQLCQDPKVTFAAYRQPHPLENSIEITIKPKGFAGVKLLSENINNLLSQVSNLKESFIKKVQKYKEKNSYYEEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYB7</accession>
    <name>A0A1J1GYB7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein phosphatase PPM6, putative</fullName>
            <ecNumber evidence="3">3.1.3.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PPM6</name>
        <name evidence="3" type="ORF">PGAL8A_00505300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530281.1">
        <property type="nucleotide sequence ID" value="XM_028673872.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYB7"/>
    <dbReference type="GeneID" id="39733586"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00505300"/>
    <dbReference type="OMA" id="EWILIMV"/>
    <dbReference type="OrthoDB" id="10264738at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.40.10:FF:000067">
        <property type="entry name" value="Protein phosphatase PPM6, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47992">
        <property type="entry name" value="PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="2">
        <location>
            <begin position="418"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="702" mass="83013" checksum="CB1A5F4F78BA533B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYH1</accession>
    <name>A0A1J1GYH1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00509000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530318.1">
        <property type="nucleotide sequence ID" value="XM_028673913.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYH1"/>
    <dbReference type="GeneID" id="39733623"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00509000"/>
    <dbReference type="OrthoDB" id="376418at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012588410" description="C2H2-type domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="429" mass="51042" checksum="10289D47B857D6EB" modified="2017-02-15" version="1">MKFIFILHILLYFLIKFIFCKNEYVTSEKNQINSESNKNDNLDNIDEAELEAKKKEFNVISENSEDTYFEDTSELIYYDDNLDNLISEGFLENDENVKKLTKKLTNFLGELIEDATSKNENFLEIVDNKLYDTESFDFPLKYILNDNKKETFNQNIGIMEFSCPICGDYFNVDECNYSIPEHKYIEKLICSKNNKSDLFNKNSSLFFHYLDKKKFNPIKVKNLSFCPDVNKIRQKSSTIENEQNKKTDKSMKNQALLSLNNHFEETEIHKLKKYLLYFKEVSNKLTTHNKNIEENYDLYKYIKILKYIEHLRFICVTNTCAKCFFNLVHALDFIIHNSLLQYRKSYFTLRNISINVIKEMEKLTKILAKLKDKNSYSNKYKYYKKYISIEASAKNMILLSINNYQKILEKEFLKLPKKSLKLTEEKSNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZD0</accession>
    <name>A0A1J1GZD0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Kinase</fullName>
            <ecNumber evidence="8">2.7.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00036300</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>1D-myo-inositol 1,3,4,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12717"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57660"/>
            <dbReference type="ChEBI" id="CHEBI:57733"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.140"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>1D-myo-inositol 1,4,5-trisphosphate + 2 ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + 2 ADP + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:32359"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57733"/>
            <dbReference type="ChEBI" id="CHEBI:203600"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.151"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the inositol phosphokinase (IPK) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.-.-" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530725.1">
        <property type="nucleotide sequence ID" value="XM_028674364.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZD0"/>
    <dbReference type="GeneID" id="39728887"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00036300"/>
    <dbReference type="OMA" id="NNEIYCL"/>
    <dbReference type="OrthoDB" id="338650at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047326">
        <property type="term" value="F:inositol-1,3,4,6-tetrakisphosphate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008440">
        <property type="term" value="F:inositol-1,4,5-trisphosphate 3-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032958">
        <property type="term" value="P:inositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.160">
        <property type="entry name" value="Inositol polyphosphate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005522">
        <property type="entry name" value="IPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038286">
        <property type="entry name" value="IPK_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12400">
        <property type="entry name" value="INOSITOL POLYPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12400:SF51">
        <property type="entry name" value="INOSITOL POLYPHOSPHATE MULTIKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03770">
        <property type="entry name" value="IPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8 10" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="793"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="105"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="800"/>
            <end position="818"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00036164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00036525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG97926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1183" mass="140922" checksum="DC0C31DE4EA2F857" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZG8</accession>
    <name>A0A1J1GZG8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fam-g protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00042700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG97998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530795.1">
        <property type="nucleotide sequence ID" value="XM_028674443.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZG8"/>
    <dbReference type="GeneID" id="39728952"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00042700"/>
    <dbReference type="OMA" id="MEWNDEN"/>
    <dbReference type="OrthoDB" id="10656675at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="303" mass="35698" checksum="AD1A44A32D77A30A" modified="2017-02-15" version="1">MNTFPFCLKVATFSFLIWIFQYFLNHNFSKSSYNKNIPATKFASKFKRTLAEVRKSQKTGFSLDDIKFVDEDCEEERTSITEEKKKKKYPKREKFPQKKKISKKKTAVKSGDHKEKSDYSSDEEREDESDESFSFSPELSMEWNDENILMLDKFPNQIKGMNTNRGARETVDEDYKKDLDIFEPSCPYKDKGRISDESLKDVTTKFDEILLSSKEKFDNHANVESEKTKTREQALRGAEKSDEKHKEQEIKDKQKHAQLSSDTKEEDEKRKKKSNVQLGKRWNEAICSMWKGFKNKTNKKDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZK3</accession>
    <name>A0A1J1GZK3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CBS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00033950</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530702.1">
        <property type="nucleotide sequence ID" value="XM_028674339.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZK3"/>
    <dbReference type="GeneID" id="39728863"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00033950"/>
    <dbReference type="OMA" id="FSENNEM"/>
    <dbReference type="OrthoDB" id="10299406at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="366" mass="43268" checksum="A1C0424916B54704" modified="2017-02-15" version="1">MELNETNKLNDKKKKNRLCGKLIYSIRDLFMLTYVNSLLPIHNNILLVHINLPFHIGLKNLIKNQLYFLLIYEKDIIGHVNHFVLLDFFIYFYNFLKFPDIKNSNDCNTITKKVSDPSEFTFKDILNISENSKDFKIFDSNSKCIEVFDHFLNFNDEHIYINDKTKSMISSAIKKKDIIYYILMNLKGKYSELNLSINDCIKKNTTTAYDNSSLINVLIKMQKKKLYFIPIVKKDTKKYIDYFSANDFLALYCKSISEKWNINPDKEVTYFISLLRTKEKEMKEKQNNIPYSYSDLLNKNDLNISKSVLNFSENNEMIKYNKELTIKESLKKLFFSKINALIVLNESNNVKGFLTFRSLFNHLMHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZN5</accession>
    <name>A0A1J1GZN5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glideosome-associated protein 40, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">GAP40</name>
        <name evidence="3" type="ORF">PGAL8A_00037200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530734.1">
        <property type="nucleotide sequence ID" value="XM_028674374.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZN5"/>
    <dbReference type="GeneID" id="39728896"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00037200"/>
    <dbReference type="OMA" id="VGCGEEY"/>
    <dbReference type="OrthoDB" id="363842at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="275"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="302"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="368"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="389"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="400"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="425"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="440"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="451"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="462" mass="52342" checksum="AFD6DCCD14DB2F23" modified="2017-02-15" version="1">MAKLSLPEWSDVERYFKDPELITAEILFVALTLCNVFVMYRLFLDVIPFPIFVTWWQLAQGLLVAYVCGELGREFPKLAYFPKVEINENMLKVLFIPSIFYCLMLVLSNYLLYKTPCIASYPVLVSFTVVFHHLTRFVGCGEEYMPLRWQSIFFLLVAFIIGCFDSKIMGKGVILWALLYALSSAIFRAGFMQKIMHLVDGRGNTLHNNQHLLGVLILPILIILSGEWTVFQYMPYDFTSLHTWQMWGCLITVGTMPFIKNVISNRLVRRTGQGPWRFLEILSIILVFLIGMTFNAPTYKGYIAILCVIIGRSIGAFDVLLNASDYMLAEDERRRKNPRSNYAKNRQSTQASKPFLSSADNEEDEESSYSSNDSKSYQGSQDYDDKESVNSSSQQYSVNKGTSRMGSSSNQTSNAGISGDESRMGSKASASRTSGRGSGFQSKSKLSRNYSSKEREMLDSQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZP1</accession>
    <name>A0A1J1GZP1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase S9 prolyl oligopeptidase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00052100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S9A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530883.1">
        <property type="nucleotide sequence ID" value="XM_028674541.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZP1"/>
    <dbReference type="GeneID" id="39729046"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00052100"/>
    <dbReference type="OMA" id="DKHNICC"/>
    <dbReference type="OrthoDB" id="248387at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.120">
        <property type="entry name" value="Prolyl oligopeptidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051543">
        <property type="entry name" value="Serine_Peptidase_S9A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11757:SF19">
        <property type="entry name" value="PROLYL ENDOPEPTIDASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11757">
        <property type="entry name" value="PROTEASE FAMILY S9A OLIGOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1046" mass="126791" checksum="1042D6264B44889F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZZ9</accession>
    <name>A0A1J1GZZ9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00058700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530949.1">
        <property type="nucleotide sequence ID" value="XM_028674614.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZZ9"/>
    <dbReference type="GeneID" id="39729112"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00058700"/>
    <dbReference type="OMA" id="CEMDNIN"/>
    <dbReference type="OrthoDB" id="372864at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.20">
        <property type="entry name" value="Insect antifreeze protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="876"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="992"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="376"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="691"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="877"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="902"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="992"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1008"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1031"/>
            <end position="1043"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1051"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1069"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1081"/>
            <end position="1094"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1260" mass="151921" checksum="389E250B388450EC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H002</accession>
    <name>A0A1J1H002_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peptide release factor, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00445500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529677.1">
        <property type="nucleotide sequence ID" value="XM_028673201.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H002"/>
    <dbReference type="GeneID" id="39732988"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00445500"/>
    <dbReference type="OMA" id="AVFTMMP"/>
    <dbReference type="OrthoDB" id="2019491at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003747">
        <property type="term" value="F:translation release factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005139">
        <property type="entry name" value="PCRF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050057">
        <property type="entry name" value="Prokaryotic/Mito_RF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43804">
        <property type="entry name" value="LD18447P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43804:SF7">
        <property type="entry name" value="LD18447P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03462">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00937">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="Release factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0488">Methylation</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptide chain release factor" evidence="4">
        <location>
            <begin position="92"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="394" mass="46500" checksum="B35E77FB82FA20F7" modified="2017-02-15" version="1">MGRHIKILNKLFFIRRYNFCSTNLTYLKNKQKELLIELADKSISDVCENKETLKIKKIQKTSKIFKSLYEELNIYKQLLMESINDKEEFQKKIMNDDDIKQLNNNIQNIQDTVIEDIIDFYKNFVNDDHHLDTNEIKMEITAGVGGLESKLFCKELFNMYENFCKIRNYEYELKNKISDDIKGNKSIVAYIKGKNVYEDFVQEIGIHRVQRIPINSKKIQTSTSIVLIFDEKSKMDKIKKKINFSKKDLVIETKRSGGAGGQSVNKNETCVKVIHKPTNIFVEVQKTSSQIQNKSIAIELLKNKLYNFYYEQERINFLKDKKNQKQSGDRSEKIRTYNFLHNVVIDHVANVEFSDIEKFFKGDHLIHLINKKKQIFYQNIIEETLKYIFSSIDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0E3</accession>
    <name>A0A1J1H0E3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00065600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028531014.1">
        <property type="nucleotide sequence ID" value="XM_028674686.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0E3"/>
    <dbReference type="GeneID" id="39729181"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00065600"/>
    <dbReference type="OMA" id="EYAEACC"/>
    <dbReference type="OrthoDB" id="10689625at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053210">
        <property type="entry name" value="ANKRD12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24149:SF14">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24149">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="460"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="857"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="169"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="197"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="473"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="498"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="528"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="553"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="583"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="608"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="638"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="663"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="693"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="718"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="857"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="889"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="919"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="931"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="953"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="966"/>
            <end position="977"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1074" mass="105756" checksum="5A41A1473C72A877" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0E7</accession>
    <name>A0A1J1H0E7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-f protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00036000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530722.1">
        <property type="nucleotide sequence ID" value="XM_028674361.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0E7"/>
    <dbReference type="GeneID" id="39728884"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00036000"/>
    <dbReference type="OMA" id="DILRIHY"/>
    <dbReference type="OrthoDB" id="10462028at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012068592" evidence="1">
        <location>
            <begin position="24"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="581" mass="68289" checksum="137A0E7590358E6F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0I4</accession>
    <name>A0A1J1H0I4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">50S ribosomal protein L1, mitochondrial, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPL1</name>
        <name evidence="4" type="ORF">PGAL8A_00051000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530872.1">
        <property type="nucleotide sequence ID" value="XM_028674528.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0I4"/>
    <dbReference type="GeneID" id="39729035"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00051000"/>
    <dbReference type="OMA" id="NGWLDFH"/>
    <dbReference type="OrthoDB" id="767661at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00403">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_uL1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_uL1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36427">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN L1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36427:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL1M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="Ribosomal protein L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG98075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="352" mass="41288" checksum="AE70A41AAA754B4E" modified="2017-02-15" version="1">MKISLFLNAHITSKINRNYKKKIFFIEKRERKYIPFYDIKKEKKKRQKTEEAENKDDEENKKKNEVFFTNLVPTISPMKGLKLLFSFKNSNESLLDKNEKINFNLIIRIDIKRESLRGMCNLVHSVDKNKKILVLVDEENKNLKKYGADYVGLDYINKIKNGWLDFNICITNFKNINKILPIAKILGPKKLMPNIKSDTLVDNLEETIKKIKSGNRIEYRSEQVDINTFKLYNQIYNLESVDLNSIANINVNIATMDMNLYHILDNIKSFVTEIIKNNVHSTHNDKVNKSTFTWPPITSKKKKKLQLQSNLFNKSEENSESFLLGAYITFNKFPKIFLKPNLLYPHSDGYSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0X7</accession>
    <name>A0A1J1H0X7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00054400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530906.1">
        <property type="nucleotide sequence ID" value="XM_028674567.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0X7"/>
    <dbReference type="GeneID" id="39729069"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00054400"/>
    <dbReference type="OMA" id="CHINTHN"/>
    <dbReference type="OrthoDB" id="10249433at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277">
        <property type="entry name" value="ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277:SF81">
        <property type="entry name" value="PROTEIN ABHD13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="2">
        <location>
            <begin position="45"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="696"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="696"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="706"/>
            <end position="719"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="907" mass="104187" checksum="9B99516D017B9E7F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1U0</accession>
    <name>A0A1J1H1U0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein ISD11, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00507200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I LYR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530300.1">
        <property type="nucleotide sequence ID" value="XM_028673893.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1U0"/>
    <dbReference type="GeneID" id="39733605"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00507200"/>
    <dbReference type="OMA" id="NYSVYFT"/>
    <dbReference type="OrthoDB" id="275715at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990221">
        <property type="term" value="C:L-cysteine desulfurase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20264">
        <property type="entry name" value="Complex1_LYR_LYRM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045297">
        <property type="entry name" value="Complex1_LYR_LYRM4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051522">
        <property type="entry name" value="ISC_assembly_LYR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056326">
        <property type="entry name" value="ISD11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13166:SF7">
        <property type="entry name" value="LYR MOTIF-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13166">
        <property type="entry name" value="PROTEIN C6ORF149"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23511">
        <property type="entry name" value="Microp_apicomplexa_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="87" mass="10635" checksum="A8B091506E3345FD" modified="2017-02-15" version="1">MKTNQIKNLKKIYRHILSEASKFENINYSVYFTNKAKENFREFFSNNNHNSEKLKVFEDECNDYLNMLKRQTIIHNLYHVDKPLVYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2B4</accession>
    <name>A0A1J1H2B4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Superoxide dismutase</fullName>
            <ecNumber evidence="11">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PGAL8A_00521100</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 11">
            <text>2 superoxide + 2 H(+) = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the iron/manganese superoxide dismutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="11"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530436.1">
        <property type="nucleotide sequence ID" value="XM_028674044.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2B4"/>
    <dbReference type="GeneID" id="39733744"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00521100"/>
    <dbReference type="OMA" id="LNNWWNV"/>
    <dbReference type="OrthoDB" id="239262at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.990:FF:000002">
        <property type="entry name" value="Superoxide dismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.55.40.20:FF:000001">
        <property type="entry name" value="Superoxide dismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.990">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="entry name" value="Iron/manganese superoxide dismutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001189">
        <property type="entry name" value="Mn/Fe_SOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019833">
        <property type="entry name" value="Mn/Fe_SOD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019831">
        <property type="entry name" value="Mn/Fe_SOD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42769">
        <property type="entry name" value="SUPEROXIDE DISMUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42769:SF3">
        <property type="entry name" value="SUPEROXIDE DISMUTASE [FE] 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00081">
        <property type="entry name" value="Sod_Fe_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000349">
        <property type="entry name" value="SODismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01703">
        <property type="entry name" value="MNSODISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46609">
        <property type="entry name" value="Fe,Mn superoxide dismutase (SOD), N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00088">
        <property type="entry name" value="SOD_MN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="6 10 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Manganese/iron superoxide dismutase N-terminal" evidence="12">
        <location>
            <begin position="4"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Manganese/iron superoxide dismutase C-terminal" evidence="13">
        <location>
            <begin position="89"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000349-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG97635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="198" mass="22627" checksum="38E677F7DAE285E3" modified="2017-02-15" version="1">MVITLPKLKYALNALSPHISEETLSFHYNKHHAGYVNKLNTLIKDTNYANKSLIDILKESTGAIFNNASQAWNHAFYWDSMGPNCGGEPHGEIKEKIETDFGSFSNFKNEFSNVLCGHFGSGWGWLALNNKNKLVILQTHDAGNPIKDNTGIPILTCDIWEHAYYIDYRNDRASYVKAWWNLVNWNFANENLRNAMNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H304</accession>
    <name>A0A1J1H304_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Guanidine nucleotide exchange factor, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00029600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530660.1">
        <property type="nucleotide sequence ID" value="XM_028674292.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728819"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00029600"/>
    <dbReference type="OMA" id="NPMGGYN"/>
    <dbReference type="OrthoDB" id="8068875at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051210">
        <property type="entry name" value="Ub_ligase/GEF_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22870:SF408">
        <property type="entry name" value="OS09G0560450 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22870">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00415">
        <property type="entry name" value="RCC1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13540">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="39"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="304"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="385"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="437"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="677"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="731"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="793"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="846"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="116"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2261" mass="266658" checksum="5CC349E2F51F57BF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3M9</accession>
    <name>A0A1J1H3M9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">FACT complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PGAL8A_00038900</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the FACT complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the peptidase M24 family. SPT16 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530751.1">
        <property type="nucleotide sequence ID" value="XM_028674393.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3M9"/>
    <dbReference type="GeneID" id="39728913"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00038900"/>
    <dbReference type="OMA" id="DWCLSAR"/>
    <dbReference type="OrthoDB" id="10251642at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035101">
        <property type="term" value="C:FACT complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.150:FF:000005">
        <property type="entry name" value="FACT complex subunit SPT16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.210:FF:000001">
        <property type="entry name" value="FACT complex subunit spt16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000017">
        <property type="entry name" value="FACT complex subunit SPT16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.210">
        <property type="entry name" value="FACT complex subunit Spt16p/Cdc68p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029148">
        <property type="entry name" value="FACT-SPT16_Nlobe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056595">
        <property type="entry name" value="Fact-SPT16_PH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048969">
        <property type="entry name" value="FACT_SPT16_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013953">
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        <property type="entry name" value="Pept_M24"/>
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        <property type="entry name" value="PH-like_dom_sf"/>
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        <property type="entry name" value="RTT106/SPT16-like_middle_dom"/>
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    <dbReference type="InterPro" id="IPR040258">
        <property type="entry name" value="Spt16"/>
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        <property type="entry name" value="CDC68 RELATED"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="FACT COMPLEX SUBUNIT SPT16"/>
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        <property type="entry name" value="Peptidase_M24"/>
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        <property type="entry name" value="PH_SPT16"/>
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        <property type="entry name" value="Rttp106-like_middle"/>
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        <property type="entry name" value="SPT16"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Rtt106"/>
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        <property type="entry name" value="SPT16"/>
        <property type="match status" value="1"/>
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    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 10" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 10" id="KW-0805">Transcription regulation</keyword>
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        <location>
            <begin position="5"/>
            <end position="160"/>
        </location>
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    <feature type="domain" description="FACT complex subunit SPT16 middle" evidence="14">
        <location>
            <begin position="560"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="domain" description="Histone chaperone RTT106/FACT complex subunit SPT16-like middle" evidence="15">
        <location>
            <begin position="836"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="954"/>
            <end position="1054"/>
        </location>
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    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="485"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="956"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="1003"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1025"/>
            <end position="1039"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010779"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
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    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
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    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
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    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
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    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU367052"/>
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    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM01285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="CRG97952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1054" mass="122420" checksum="80BDE359CF4F9011" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2012-07-11" modified="2026-01-28" version="55" xmlns="https://uniprot.org/uniprot">
    <accession>I2FKC1</accession>
    <name>I2FKC1_PLAGA</name>
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        <recommendedName>
            <fullName evidence="14">Glyceraldehyde-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="14">1.2.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">GAPDH</name>
        <name evidence="17" type="ORF">PGAL8A_00222200</name>
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    <organism evidence="16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
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        <citation type="journal article" date="2012" name="Gene" volume="502" first="36" last="39">
            <title>Age of the last common ancestor of extant Plasmodium parasite lineages.</title>
            <authorList>
                <person name="Hayakawa T."/>
                <person name="Tachibana S."/>
                <person name="Hikosaka K."/>
                <person name="Arisue N."/>
                <person name="Matsui A."/>
                <person name="Horii T."/>
                <person name="Tanabe K."/>
            </authorList>
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            <dbReference type="DOI" id="10.1016/j.gene.2012.04.037"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>D-glyceraldehyde 3-phosphate + phosphate + NAD(+) = (2R)-3-phospho-glyceroyl phosphate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10300"/>
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            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="1.2.1.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="14">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 1/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 14">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="CRG94825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_028670937.1"/>
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    <dbReference type="OMA" id="YGYTCNM"/>
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        <property type="reaction ID" value="UER00184"/>
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    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
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    <dbReference type="GO" id="GO:0005829">
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004365">
        <property type="term" value="F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
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        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0006006">
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        <property type="project" value="InterPro"/>
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        <property type="term" value="P:glycolytic process"/>
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        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
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    </dbReference>
    <dbReference type="CDD" id="cd05214">
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    </dbReference>
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    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
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        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
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        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10836">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10836:SF76">
        <property type="entry name" value="GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
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    </dbReference>
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        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GAP_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00078">
        <property type="entry name" value="G3PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00846">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00071">
        <property type="entry name" value="GAPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 14" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 11 14" id="KW-0520">NAD</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 14 17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding" evidence="15">
        <location>
            <begin position="4"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="13"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="152"/>
            <end position="154"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="214"/>
            <end position="215"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="319"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Activates thiol group during catalysis" evidence="12">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00846"/>
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    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="BAM15606.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="CRG94825.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="337" mass="36825" checksum="5781CFE41FD2E5C2" modified="2012-07-11" version="1">MAVTKLGINGFGRIGRLVFRASYGNKDIEVVAINDPFMDIAHLAYLLKYDSVHGKFPCEIKTDDKNLYVNGKKINVHNERDPAQIPWGKYNIDVVCESTGVFLTKELAGAHIKGGAKKVVMSAPPKDDTPIYVMGINHEKYNPKELIVSNASCTTNCLAPIAKVLHEKFGIIEGLMTTVHASTSNQLVVDGPSKGGKDWRAGRCALTNIIPASTGAAKAVGKVLPELNGKLTGVAFRVPVADVSVVDLVCRLQKSAKYEDIVSEIKKAADGELKGILGYVEDEVVSQDFVHDSRSSIFDVKAGLALNENFFKLIAWYDNEWGYSNRILDLAIHITKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLK1</accession>
    <name>A0A1J1GLK1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00092400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526042.1">
        <property type="nucleotide sequence ID" value="XM_028671821.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLK1"/>
    <dbReference type="GeneID" id="39729448"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00092400"/>
    <dbReference type="OMA" id="HFNNTIG"/>
    <dbReference type="OrthoDB" id="420410at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38899">
        <property type="entry name" value="DOMAIN OOKINETE PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38899:SF1">
        <property type="entry name" value="PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="375" mass="44334" checksum="71DF2A9668D20D72" modified="2017-02-15" version="1">MNLPNANASLYTNQNFCTKNVEPKYKMNPFLNIKANYPMKNLSYPHINNNIILNNNSQLKLQKNKTFSIPFDMEPKIDSKYFYVKCFNNMNNTNDYSKNKNFKIFNKSDIQSNGRILCEPIIPKNNYIPQYFKNNINNSLCKIYLEKCGRVIIFDLDDTLIPTYWIRSVLFSKCHLNQDEALRELKKEIKLNKKYNFESTACSVIHLAKSMSHTIFIVTNARSDKWIDTVKWLFPNFSKLLDEHNIPIIRTEQYMEPSPLNVFEYFRYWMNAKKKKFDEILKEHWAFYYQYITNKIDFISLGDTEFEEVATYELQSSNKNIIKKAFNIKVQTGLSFEDFIGQLKLIQVALSIITKESYSYKYLALSSSVQIKMFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLQ4</accession>
    <name>A0A1J1GLQ4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00098200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526098.1">
        <property type="nucleotide sequence ID" value="XM_028672444.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLQ4"/>
    <dbReference type="GeneID" id="39729506"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00098200"/>
    <dbReference type="OrthoDB" id="369331at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012453002" evidence="1">
        <location>
            <begin position="18"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="166" mass="20258" checksum="365882B55DE74D2A" modified="2017-02-15" version="1">MKNLLFFYITLFLSCNSYIINFKNDNNSLIFRKVWNKNNRKLPNNFKLYMKRLRNAYVEIDLENRKDLTKIEIIKMFLKGVKECKNVEYLKEKMKGHVPPTTKRKLMKQKRMVNLRIHIKNTRIKKQEEVAPHKNILNFPLNQLKNINAAVLYFRHYFEKYEKNTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLS2</accession>
    <name>A0A1J1GLS2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Bromodomain protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00106300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526180.1">
        <property type="nucleotide sequence ID" value="XM_028673355.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729589"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00106300"/>
    <dbReference type="OMA" id="KQMDKQM"/>
    <dbReference type="OrthoDB" id="21449at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15398">
        <property type="entry name" value="BROMODOMAIN-CONTAINING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15398:SF4">
        <property type="entry name" value="BROMODOMAIN-CONTAINING PROTEIN 8 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bromo" evidence="5">
        <location>
            <begin position="927"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="76"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="282"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="664"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="7"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="219"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="322"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="835"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="1237"/>
            <end position="1264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="664"/>
            <end position="678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1731" mass="206497" checksum="60B28A2F87C7CEE0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLS8</accession>
    <name>A0A1J1GLS8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00107100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526188.1">
        <property type="nucleotide sequence ID" value="XM_028673444.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLS8"/>
    <dbReference type="GeneID" id="39729597"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00107100"/>
    <dbReference type="OMA" id="NLEMEMN"/>
    <dbReference type="OrthoDB" id="377493at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="81"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="342"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="543" mass="63898" checksum="582780555E042569" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLU8</accession>
    <name>A0A1J1GLU8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">2-C-methyl-D-erythritol 4-phosphate, putative</fullName>
            <ecNumber evidence="5">2.7.7.60</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">IspD</name>
        <name evidence="5" type="ORF">PGAL8A_00103000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.60" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526146.1">
        <property type="nucleotide sequence ID" value="XM_028672977.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLU8"/>
    <dbReference type="GeneID" id="39729555"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00103000"/>
    <dbReference type="OMA" id="DNEKGKC"/>
    <dbReference type="OrthoDB" id="414267at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050518">
        <property type="term" value="F:2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034683">
        <property type="entry name" value="IspD/TarI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050088">
        <property type="entry name" value="IspD/TarI_cytidylyltransf_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018294">
        <property type="entry name" value="ISPD_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32125">
        <property type="entry name" value="2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32125:SF4">
        <property type="entry name" value="2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01128">
        <property type="entry name" value="IspD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01295">
        <property type="entry name" value="ISPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009618910" evidence="4">
        <location>
            <begin position="22"/>
            <end position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="631" mass="75523" checksum="67D16FB7A04DE831" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLX0</accession>
    <name>A0A1J1GLX0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00113800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526254.1">
        <property type="nucleotide sequence ID" value="XM_028674176.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLX0"/>
    <dbReference type="GeneID" id="39729663"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00113800"/>
    <dbReference type="OrthoDB" id="376230at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="767" mass="92131" checksum="EA9C1F56807CFE6B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLY3</accession>
    <name>A0A1J1GLY3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00094100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526059.1">
        <property type="nucleotide sequence ID" value="XM_028672010.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLY3"/>
    <dbReference type="GeneID" id="39729465"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00094100"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="186" mass="22573" checksum="8A603FBDE1A660C1" modified="2017-02-15" version="1">MMDNYTHNNTDIPNRKDNLIKNSEMNVITSKDNIDDEYDNNKNIEDNIGGDKYYKEENYSEMYDLDKSKIFKNKNSSEEISDIYNMNYDKNLNEQLLLDVNSKKKKKKYENFLKSKNDNKCTELKEIPYCSFNNFEEKENDEKIKELNNNSYNMFNKEKLKKIEKKKKKNNEKKKKKKKIHMYNLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM48</accession>
    <name>A0A1J1GM48_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fam-m protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00101500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526131.1">
        <property type="nucleotide sequence ID" value="XM_028672810.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM48"/>
    <dbReference type="GeneID" id="39729540"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00101500"/>
    <dbReference type="OrthoDB" id="374985at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012949816" description="Fam-m protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="136" mass="15998" checksum="EDA1122D0FE4F0D4" modified="2017-02-15" version="1">MKLFVVTFFYFIILNTLYAKDGIYISNKREAFRNKFKKKSSLHILNNDSEKNFLQVKSENIYDPSIVYRGMENNALGISTIYYSRLMWGGVIFLVMFILVSSIGVYLYVDNLEYNSPKKRGIRNTTNYYVTNPHFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM56</accession>
    <name>A0A1J1GM56_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00102300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526139.1">
        <property type="nucleotide sequence ID" value="XM_028672899.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM56"/>
    <dbReference type="GeneID" id="39729548"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00102300"/>
    <dbReference type="OrthoDB" id="371834at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="1">
        <location>
            <begin position="125"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="211" mass="25503" checksum="E423BDF4BB2C856C" modified="2017-02-15" version="1">MDLLYINKIPELNYENEVTKKIVLKIIHKLDKQQKEESRNTNFYNRSKIINFFSEAELLFKYHDIEKKGELDIKLFPKMARQLKQIYDIRDIKRFEKEMKTKKLSKMNLPMFLTLLKRKLFQTIDDDETFKKYFDVLDMNKNKKINLDQLKMYLGLVGDKISHEEINSFISYYVENNKKLIQNDLTLDDKNLPTEIGLTVYKDILTYFKNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM72</accession>
    <name>A0A1J1GM72_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00113300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526249.1">
        <property type="nucleotide sequence ID" value="XM_028674121.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM72"/>
    <dbReference type="GeneID" id="39729658"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00113300"/>
    <dbReference type="OrthoDB" id="372628at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="432" mass="51797" checksum="E597EB1B5A7991A7" modified="2017-02-15" version="1">MEEKFLQTHITLLFYLILLFYLKNFTVNFIEIPKKILHYIKVYYSFLIILTAVGFFSRLIILIQIFIVQKINEILNKFLNSNSKNVKIKKNIRFNKDSSKLKLKKKKLSDIDNNFKYLKNNNLDKLNHDKFSKGNIDLNKKNYINHNQDANKYDKKREAYIPYIIKKRKKNKEKNIENDQIKNEDIKRKAKDKMKNDQDTETYLETKENTNFDYSYKQKYNFFTHFSNVSYNEENSVEKNNNMNCNKNNNVNSNTTEHLDNDLYNSKNKYTNNNIKNDIKTNSNNNIYNNPNNSFINYRDSNCSYTCVNEMNKKINDTFTKSEKIPLKSILKKNILSNDSLKIKNNQKVKSDKHIRFNADIETYFFEKNSFEEDAYNNDNDSKQKFYRIFDAYNLTNTNIFSYCNVSYNLNLVFNDVINSFFVYKDKLVKKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMB7</accession>
    <name>A0A1J1GMB7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Apicoplast ribosomal protein L21, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00120700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial ribosomal protein bL21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526322.1">
        <property type="nucleotide sequence ID" value="XM_028674719.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMB7"/>
    <dbReference type="GeneID" id="39729732"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00120700"/>
    <dbReference type="OrthoDB" id="5994at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01363">
        <property type="entry name" value="Ribosomal_bL21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028909">
        <property type="entry name" value="bL21-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036164">
        <property type="entry name" value="bL21-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001787">
        <property type="entry name" value="Ribosomal_bL21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018258">
        <property type="entry name" value="Ribosomal_bL21_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00061">
        <property type="entry name" value="L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21349">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21349:SF7">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL21C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00829">
        <property type="entry name" value="Ribosomal_L21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141091">
        <property type="entry name" value="L21p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01169">
        <property type="entry name" value="RIBOSOMAL_L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0934">Plastid</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="308" mass="37777" checksum="F28F62792CC782A7" modified="2017-02-15" version="1">MFFFGTYFLFLYILILYFSIPIFSNKINRTYNDKIYFNFINNFYKYKLNRSKKLNVLISSPAQIKLSEIEDNRDRSGKYCVIEICGKIRWVEEGRYYDFFRIKQEENKKIYLNRVFFYNNEEGKLFFGNPFLDNVRIKATIVNHFRGKKIYRLKFKRKKNYKKFYGFRQEMTRILINKIECNNELIGEGSRKFNFFKDDSIYYILNRIHNIVKPSSELKYLKRHFIDYLNSFCSLKFETFYKHRGNYKKEKMLKNILKTKKLSKRPEVIEEVKKIEEEKRNKRLNKIDPLEDFDPVANESMIKENFYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMI4</accession>
    <name>A0A1J1GMI4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Spindle assembly abnormal protein 6, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SAS6</name>
        <name evidence="8" type="ORF">PGAL8A_00136100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526478.1">
        <property type="nucleotide sequence ID" value="XM_028674893.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMI4"/>
    <dbReference type="GeneID" id="39729886"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00136100"/>
    <dbReference type="OMA" id="KQYMRLE"/>
    <dbReference type="OrthoDB" id="49058at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005813">
        <property type="term" value="C:centrosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.210.20">
        <property type="entry name" value="Spindle assembly abnormal protein 6, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032396">
        <property type="entry name" value="SAS-6_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038558">
        <property type="entry name" value="SAS-6_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44281">
        <property type="entry name" value="SPINDLE ASSEMBLY ABNORMAL PROTEIN 6 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44281:SF2">
        <property type="entry name" value="SPINDLE ASSEMBLY ABNORMAL PROTEIN 6 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16531">
        <property type="entry name" value="SAS-6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Spindle assembly abnormal protein 6 N-terminal" evidence="7">
        <location>
            <begin position="197"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="393"/>
            <end position="695"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="792" mass="93545" checksum="DE7BC0444A983A7B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMI9</accession>
    <name>A0A1J1GMI9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">phenylalanine--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Phenylalanyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PGAL8A_00132200</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>tRNA(Phe) + L-phenylalanine + ATP = L-phenylalanyl-tRNA(Phe) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526439.1">
        <property type="nucleotide sequence ID" value="XM_028674849.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMI9"/>
    <dbReference type="GeneID" id="39729847"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00132200"/>
    <dbReference type="OMA" id="GYTICAD"/>
    <dbReference type="OrthoDB" id="4457at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.380:FF:000002">
        <property type="entry name" value="phenylalanine--tRNA ligase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.380">
        <property type="entry name" value="Ferrodoxin-fold anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005121">
        <property type="entry name" value="Fdx_antiC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036690">
        <property type="entry name" value="Fdx_antiC-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002319">
        <property type="entry name" value="Phenylalanyl-tRNA_Synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538:SF41">
        <property type="entry name" value="PHENYLALANINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538">
        <property type="entry name" value="PHENYLALANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03147">
        <property type="entry name" value="FDX-ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01409">
        <property type="entry name" value="tRNA-synt_2d"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00896">
        <property type="entry name" value="FDX-ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54991">
        <property type="entry name" value="Anticodon-binding domain of PheRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51447">
        <property type="entry name" value="FDX_ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="13">
        <location>
            <begin position="138"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="FDX-ACB" evidence="14">
        <location>
            <begin position="356"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG93617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="447" mass="54222" checksum="AD23B93FFD2C788D" modified="2017-02-15" version="1">MTLPKIILSNEGRILYNTKNHPIRTVKNMIEHFFKFENFDNLNYETSIKQNFDELLVPLSHPARSIKDTFYLNENYIKNFNFLFENYYIRLDTLNKFYKYYLSNKILNHDNIKLMRTHMTTHLPYLLKKNYRNVIYTGTVYRRDEIDKYHFPIFHQTDGFLMRSESFEVEADLKIKLEKLINYLFKSNKIEMKWEDNTSFPFTDPSYELYIKRENDKKWIEILGCGKIKKEVIYMSLYEKDIKKIIENEIYTFDKNLKSTLDNYPNNKILFQTKNKEECNSIINKFCNKQLNNQITLKINEFLKNINYQGWAFGIGLERLCMLLYGIEDIRLLWSNDKRFINQFKENEITKFYPFSNFPSIKKDISFYINDNFKENIFFQLCRDIAHENIEEVKKVDHYFNPKTNETSVCYRITYRSHNQNLTHKFVNNIQNKIIESLIKECSVHVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMU0</accession>
    <name>A0A1J1GMU0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Malate:quinone oxidoreductase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00145600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; tricarboxylic acid cycle.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526572.1">
        <property type="nucleotide sequence ID" value="XM_028674996.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMU0"/>
    <dbReference type="GeneID" id="39729980"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00145600"/>
    <dbReference type="OMA" id="NFLFEVP"/>
    <dbReference type="OrthoDB" id="498204at2759"/>
    <dbReference type="UniPathway" id="UPA00223"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047545">
        <property type="term" value="F:(S)-2-hydroxyglutarate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008924">
        <property type="term" value="F:L-malate dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006231">
        <property type="entry name" value="MQO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43104">
        <property type="entry name" value="L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43104:SF2">
        <property type="entry name" value="L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06039">
        <property type="entry name" value="Mqo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="512" mass="58814" checksum="B5C3B3605FF6194D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN41</accession>
    <name>A0A1J1GN41_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00158900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526702.1">
        <property type="nucleotide sequence ID" value="XM_028675141.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN41"/>
    <dbReference type="GeneID" id="39730114"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00158900"/>
    <dbReference type="OMA" id="SYYENIM"/>
    <dbReference type="OrthoDB" id="385278at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="365" mass="43593" checksum="5EC48312D494E12A" modified="2017-02-15" version="1">MKKVVKVSFLVVVFYMFLLLQKVTICTYIDITHFSEDLIDNIMKSEIYMSNHLKFNENNKSNKRKKRNESDIDDINLLTSMLSQIIPYNFSFYSITIPDGNIDSFNSDTNNFLDLVNIYDPDINNTITHHLNKTQPIKGCENDIKNYNCDKDVIKCITLNKKDLSESCKKSLNNSLLYSCIDDFLLYCIDYSKFSKVYKCLKENFFQLSNKCLNILSYYENIMQKLHKMKSKPYDNEEFIFFEKDKINFSDSKNNIDSTNNLKKNSESNENNNKQNILHSSNKQKLDISDNLRKEYSHYILPSMNYHYLGHIRPKNYFYKYILYFFEFLFILFVVYVIIIYIKKYYVMDSNKFYIIKEKKKLAKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNB0</accession>
    <name>A0A1J1GNB0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ras GTPAse, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00145500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526571.1">
        <property type="nucleotide sequence ID" value="XM_028674995.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNB0"/>
    <dbReference type="GeneID" id="39729979"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00145500"/>
    <dbReference type="OMA" id="GEIPIAC"/>
    <dbReference type="OrthoDB" id="8954335at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24073">
        <property type="entry name" value="DRAB5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="388" mass="46191" checksum="7D4555D28F03CF13" modified="2017-02-15" version="1">MESLKILVLGDLGVGKSSFLKLISEKFYEIYPINYFDYFIYSDEKEENKQIVRAKDLANNNCAQKNVETIVESMFFQAKKNFLEFIENKMNTQNFFFEERHKYTYGFEIYTFLWNKDNEYNNKFIKNIPLNMLKNDELLNNNNSLNSDDNNVLLIEFFEIGGVQTYSYIRNIFYEKHDGILLVYDSSNNKSYHNLVKWLYELYINTKPPSDIFCVVKKKENTLWNFFKKKKKKDNSNEENINTIYTEDNYNEFRNIKYNDDDFLSDENSDIEKGYYKNGDRILKGEIPIACVATKIDKKNSKEKPAFAKTPKKSCFYDIFFSDFFSKEPIYESKNNLKIKKEILKKLEHHISEAIEIKASSIDCVVDIDNFLNFLKTAYNKKYKFPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP24</accession>
    <name>A0A1J1GP24_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00392200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527039.1">
        <property type="nucleotide sequence ID" value="XM_028670270.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP24"/>
    <dbReference type="GeneID" id="39732452"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00392200"/>
    <dbReference type="OrthoDB" id="372427at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="435" mass="52152" checksum="87ED7E4073C2B823" modified="2017-02-15" version="1">MSHSYSHNNFSLDENDEGKLIPNKKNINGFIKIYPKNKRNSNTCENIRTKSLNINRRECKNYNRNYTTNSMRNSRLLSHEYIDEILRIDKYIQHPYSINNNYDKKKWINAHNLRNRMKEYDIMTRKKLYENNIINKKAKFDRERYVILNRIPIFREAFPIEKDPSDKNKEAIIRTYLKTHASYLLSESKKNKKNFRKKKKFNNSSNFYVEKNNPFNYINYKQNNNKFSENYKNGDSSYNLQKKKNNEKIKNRSKTPFTNRNLNDCEIVINGIYNKVSNVDERRNFPKTSSRQLSDNHSTNNKIHLNIKNFPKGLFNDNEKRESCEWNSNITKINMCNSNNIRNSNIYDYSNECKNKNTNDNSERNTYYEINSRDNFSNQSNYTDECLTKLSDNSKDFYTKNNIKNDNIFKKDRYSLLGKIKNNKDVKVKLVLNKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP40</accession>
    <name>A0A1J1GP40_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Proteasome maturation factor UMP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00075300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525869.1">
        <property type="nucleotide sequence ID" value="XM_028675145.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP40"/>
    <dbReference type="GeneID" id="39729278"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00075300"/>
    <dbReference type="OrthoDB" id="15001at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05348">
        <property type="entry name" value="UMP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="124" mass="14743" checksum="A311313A49DB5653" modified="2017-02-15" version="1">MTNNYLDRLDYDFKIKDVTNIRDINLQAKENNIESFHEKILLNEEKNYLKRTGLIYGTQEVFKNIMDREIVAISRRLPGIKSSLLSLDILRNTIDRIDSHEYMEKLVDHTTEPLCEIIERKMNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPE1</accession>
    <name>A0A1J1GPE1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein ARV</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00387600</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Regulates also the sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Endoplasmic reticulum membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the ARV1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526993.1">
        <property type="nucleotide sequence ID" value="XM_028670219.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPE1"/>
    <dbReference type="GeneID" id="39732406"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00387600"/>
    <dbReference type="OrthoDB" id="2192830at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032541">
        <property type="term" value="C:cortical endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032366">
        <property type="term" value="P:intracellular sterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097036">
        <property type="term" value="P:regulation of plasma membrane sterol distribution"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006665">
        <property type="term" value="P:sphingolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016125">
        <property type="term" value="P:sterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007290">
        <property type="entry name" value="Arv1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14467">
        <property type="entry name" value="ARV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14467:SF0">
        <property type="entry name" value="PROTEIN ARV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04161">
        <property type="entry name" value="Arv1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 10" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="451"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="480"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="508"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="536"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG94172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="562" mass="68281" checksum="ABB21AA440337259" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPN9</accession>
    <name>A0A1J1GPN9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00409300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527210.1">
        <property type="nucleotide sequence ID" value="XM_028670460.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732623"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00409300"/>
    <dbReference type="OMA" id="NMDNTIK"/>
    <dbReference type="OrthoDB" id="197155at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019433">
        <property type="term" value="P:triglyceride catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07224">
        <property type="entry name" value="Pat_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033562">
        <property type="entry name" value="PLPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12406">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 IPLA2 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12406:SF7">
        <property type="entry name" value="PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1276"/>
            <end position="1299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1502"/>
            <end position="1518"/>
        </location>
    </feature>
    <feature type="domain" description="PNPLA" evidence="4">
        <location>
            <begin position="488"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="234"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="269"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1834" mass="219590" checksum="F7E88B5ECE2EE05C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPS3</accession>
    <name>A0A1J1GPS3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA 4-demethylwyosine synthase (AdoMet-dependent)</fullName>
            <ecNumber evidence="4">4.1.3.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PGAL8A_00072200</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>N(1)-methylguanosine(37) in tRNA(Phe) + pyruvate + S-adenosyl-L-methionine = 4-demethylwyosine(37) in tRNA(Phe) + 5'-deoxyadenosine + L-methionine + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:36347"/>
            <dbReference type="Rhea" id="RHEA-COMP:10164"/>
            <dbReference type="Rhea" id="RHEA-COMP:10165"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64315"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="EC" id="4.1.3.44"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">tRNA modification; wybutosine-tRNA(Phe) biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TYW1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.44" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525840.1">
        <property type="nucleotide sequence ID" value="XM_028674823.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPS3"/>
    <dbReference type="GeneID" id="39729247"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00072200"/>
    <dbReference type="OrthoDB" id="271553at2759"/>
    <dbReference type="UniPathway" id="UPA00375"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102521">
        <property type="term" value="F:tRNA-4-demethylwyosine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031591">
        <property type="term" value="P:wybutosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013917">
        <property type="entry name" value="tRNA_wybutosine-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034556">
        <property type="entry name" value="tRNA_wybutosine-synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13930">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT TRNA 4-DEMETHYLWYOSINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13930:SF0">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT TRNA 4-DEMETHYLWYOSINE SYNTHASE TYW1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08608">
        <property type="entry name" value="Wyosine_form"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00284">
        <property type="entry name" value="tRNA_wybutosine-synthesizing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01071">
        <property type="entry name" value="tRNA_wybutosine-synthesizing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Radical SAM core" evidence="14">
        <location>
            <begin position="521"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="844"/>
            <end position="863"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG93018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="863" mass="102549" checksum="7F93207AAF66E676" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPW7</accession>
    <name>A0A1J1GPW7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">S1 motif domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00104100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526157.1">
        <property type="nucleotide sequence ID" value="XM_028673099.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPW7"/>
    <dbReference type="GeneID" id="39729566"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00104100"/>
    <dbReference type="OrthoDB" id="371419at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012791739" description="S1 motif domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="221" mass="26630" checksum="43912F504876DB8D" modified="2017-02-15" version="1">MLHFFVIFLLINLTYSININVKNYLFFNDNFNNIQKCKIFKTKRIFERDMKNNIIYKQIKEENYPFKKYSIDDVYYGRILSINQRKIKLDILCDRKAYLNTSEYFSLEGLQKYIFLIIKIHNIIKVRIARIDNIHKKIIVDIKKYTNEEILSSFKNTNNLINSKILDIRDNYVLLYLAPKIHAKLIIKQSDDLNKYKIGNNILTKIDYFDKVKNELYVKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ25</accession>
    <name>A0A1J1GQ25_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00194100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000030">
        <property type="protein sequence ID" value="CRG94544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527359.1">
        <property type="nucleotide sequence ID" value="XM_028670625.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ25"/>
    <dbReference type="GeneID" id="39730467"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00194100"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="90"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="240" mass="28333" checksum="0B16EBD203CFA3CD" modified="2017-02-15" version="1">MSTTKIYNKSRKKTMIKFSIKIIIFTFLKWMLQDSNNKCKINLEKKLNLESKRSLAESKKDLNSENEVIKMCISGELKFYKKRDVAKITLHLQKKEKDENDKKVEETNEEIEEKIIEMDDLNKKLDEFNDMLEELNDMIEDKLENDALDNIDIEQGYLIEITKKKNKICFNKKKLRKYLKKLKPEPIVSILFLPFVACILSMITFVTDDYQLYNITVLFLSLSLVLTSILVINTKENKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQJ1</accession>
    <name>A0A1J1GQJ1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serpentine receptor, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00193000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000029">
        <property type="protein sequence ID" value="CRG94532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527347.1">
        <property type="nucleotide sequence ID" value="XM_028670612.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQJ1"/>
    <dbReference type="GeneID" id="39730455"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00193000"/>
    <dbReference type="OMA" id="AYKIEFR"/>
    <dbReference type="OrthoDB" id="9975959at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007186">
        <property type="term" value="P:G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019236">
        <property type="term" value="P:response to pheromone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047831">
        <property type="entry name" value="GPR180/TMEM145"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019336">
        <property type="entry name" value="GPR180/TMEM145_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23252">
        <property type="entry name" value="INTIMAL THICKNESS RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23252:SF24">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 145"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10192">
        <property type="entry name" value="GPR180-TMEM145_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="297"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="327"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="357"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="394"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="422"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="GPR180/TMEM145 transmembrane" evidence="2">
        <location>
            <begin position="230"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="461" mass="55085" checksum="C90A5415FCE5A86B" modified="2017-02-15" version="1">MIRRILKKKRLITFLFLFLYFTNLEEKFIKKEVEKIPFVSIFPYTKKYKNNFFLSVLLYVKKMRVEFHNSLLKRINLNNFFVSSKVIYGLYDDENISKFSNFCYSKSSKKGILILSNLFIPNSKLLILDKTDDEIYNYAKNKKGKKCEDLEKEALFTHSFKDIPSEFLNSSYFIYETNIDQELTEKYLNFILINCGNKIKNAFKIEFRNNINFLKNHFSCEEQGLIEIHMLLTVILIVLSLVYFRKREKLTQINSTLGESINCAFLFFFFSNLFYSIHLISYASNGSGFSILKVLSQIYESIFDCFIITIIFYMYNKNNNKKFEETFKLSFTYSILKFIYILFEIQNHQDLNLYSTLHSAIGFPFIVNRIIVAILIYINGNKLLKEKKDLNEKFFILFDTLLYNIWILSIPVHYFFMKNSSLHFTHLFIHFVNLFILIYLVYNLSQKKYEILDSKHPYLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQJ8</accession>
    <name>A0A1J1GQJ8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Small subunit rRNA processing factor, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00126600</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526381.1">
        <property type="nucleotide sequence ID" value="XM_028674785.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQJ8"/>
    <dbReference type="GeneID" id="39729791"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00126600"/>
    <dbReference type="OMA" id="YIHTING"/>
    <dbReference type="OrthoDB" id="269804at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070037">
        <property type="term" value="F:rRNA (pseudouridine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005304">
        <property type="entry name" value="Rbsml_bgen_MeTrfase_EMG1/NEP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12636">
        <property type="entry name" value="NEP1/MRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12636:SF5">
        <property type="entry name" value="RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE NEP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03587">
        <property type="entry name" value="EMG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="7" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="190"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG93559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="398" mass="47203" checksum="15DD43E644B8BC10" modified="2017-02-15" version="1">MIEKNNKNIKKGKFYRTKKKNKNEEKVNKLGYNDLRKNKKVNKKSETFKNFKKNKLETNQKFKNKTKTHFNNKYNNKNRILNNYKEVDSENSYDNCNSGFDEDKKEENNLNNNENITSDLNIKNRTVDYVDYINMIKNSDEYNLDKIKKEYDENNDINNEKVFKIFLIFSPLAITSIKNKSCLINADDHMTLFEKKLKNLENLMKIESNDNNKKNIKKKIDSVKNKLDNIRSDVLFYTLLCLRDSILNKKQKLQIYIYTINNLLIYVSPLFRIPRNFTLFKKVMLSLLKKGELYDDNKQILLKILPHSIKYYIGNTVCVGISNDGFPTDAKKFADKVKKTNNDYSFFVSLSYIYDVTKFIEIIKKKESEEFSFDYLIRLSDLKLSPITICSKLTYFLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQN6</accession>
    <name>A0A1J1GQN6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00105900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526176.1">
        <property type="nucleotide sequence ID" value="XM_028673311.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQN6"/>
    <dbReference type="GeneID" id="39729585"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00105900"/>
    <dbReference type="OMA" id="PRKKRIM"/>
    <dbReference type="OrthoDB" id="375837at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1710.10">
        <property type="entry name" value="IpaD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036708">
        <property type="entry name" value="BipD-like_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="207" mass="24718" checksum="284E8F3F15788652" modified="2017-02-15" version="1">MKFFKYNLFLLNIFFFFFVFILFSSSEKMLDIGSLPISEKRLAFNLIQIYNETKDAQNNFYVNFQNTQKMFNEIKKENNNNNNSSLPSFLQIKSKGPVEEETIWRALYDTQLRRSPPTEEVHVYSTEDIEKEYEQAKLDAFKSQIDIMKNQFEKNLQYMSKELSRQKNIKDVLNQIPLLEEEINKVQKKKPYKNGPIKKIYSTKIQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR11</accession>
    <name>A0A1J1GR11_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L6, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00235000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527766.1">
        <property type="nucleotide sequence ID" value="XM_028671077.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR11"/>
    <dbReference type="GeneID" id="39730878"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00235000"/>
    <dbReference type="OMA" id="YAHFPMK"/>
    <dbReference type="OrthoDB" id="10252633at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.930.12:FF:000003">
        <property type="entry name" value="60S ribosomal protein L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.930.12:FF:000004">
        <property type="entry name" value="60S ribosomal protein L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.930.12">
        <property type="entry name" value="Ribosomal protein L6, alpha-beta domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000702">
        <property type="entry name" value="Ribosomal_uL6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036789">
        <property type="entry name" value="Ribosomal_uL6-like_a/b-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020040">
        <property type="entry name" value="Ribosomal_uL6_a/b-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655:SF16">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655">
        <property type="entry name" value="60S/50S RIBOSOMAL PROTEIN L6/L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00347">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002162">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56053">
        <property type="entry name" value="Ribosomal protein L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL6 alpha-beta" evidence="4">
        <location>
            <begin position="12"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL6 alpha-beta" evidence="4">
        <location>
            <begin position="111"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="190" mass="21572" checksum="898B269AB78C6195" modified="2017-02-15" version="1">MKTIVSSQKVAIPDGVKVAINSRKVTVSGKYGTLRRNFRHLPVDIRINKLKKYIKVVMWFGIPDSLACIRTVCTHLKNMFTGVTKKFLYKMRLVHAHFPINSNIVDDNKRIEIRNYLGEKSVRSVKALPGVLIEKSPNVKDEIYISGADIENVSLTAALIHQSTLCRNKDIRKFLDGIYVSEVTTVEKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR63</accession>
    <name>A0A1J1GR63_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcription factor with AP2 domain(S), putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">AP2-G</name>
        <name evidence="3" type="ORF">PGAL8A_00123700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526352.1">
        <property type="nucleotide sequence ID" value="XM_028674752.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729762"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00123700"/>
    <dbReference type="OMA" id="NINREEH"/>
    <dbReference type="OrthoDB" id="372748at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2050">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="399"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1261"/>
            <end position="1298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1636"/>
            <end position="1757"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1777"/>
            <end position="1852"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2227"/>
            <end position="2290"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="777"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1438"/>
            <end position="1465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="406"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="491"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="523"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1777"/>
            <end position="1837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2235"/>
            <end position="2255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2267"/>
            <end position="2290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2396" mass="284741" checksum="97D4C31E2FE8A17C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR93</accession>
    <name>A0A1J1GR93_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">E1 ubiquitin-activating enzyme</fullName>
            <ecNumber evidence="4">6.2.1.45</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00126900</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + ubiquitin + [E1 ubiquitin-activating enzyme]-L-cysteine = AMP + diphosphate + S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine.</text>
            <dbReference type="EC" id="6.2.1.45"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the ubiquitin-activating E1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.45" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526384.1">
        <property type="nucleotide sequence ID" value="XM_028674788.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR93"/>
    <dbReference type="GeneID" id="39729794"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00126900"/>
    <dbReference type="OMA" id="WVKSPSK"/>
    <dbReference type="OrthoDB" id="10252231at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031510">
        <property type="term" value="C:SUMO activating enzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019948">
        <property type="term" value="F:SUMO activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004839">
        <property type="term" value="F:ubiquitin activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01490">
        <property type="entry name" value="Ube1_repeat2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.290.60:FF:000004">
        <property type="entry name" value="Ubiquitin-activating enzyme E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.80:FF:000005">
        <property type="entry name" value="Ubiquitin-activating enzyme E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.180:FF:000002">
        <property type="entry name" value="Ubiquitin-activating enzyme E1 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.180">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, FCCH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.80">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12550">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2660">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, SCCH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.60">
        <property type="entry name" value="Ubiquitin-activating enzyme E1, UFD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032420">
        <property type="entry name" value="E1_4HB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032418">
        <property type="entry name" value="E1_FCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042302">
        <property type="entry name" value="E1_FCCH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018965">
        <property type="entry name" value="Ub-activating_enz_E1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042449">
        <property type="entry name" value="Ub-E1_IAD_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038252">
        <property type="entry name" value="UBA_E1_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019572">
        <property type="entry name" value="UBA_E1_SCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042063">
        <property type="entry name" value="Ubi_acti_E1_SCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018075">
        <property type="entry name" value="UBQ-activ_enz_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033127">
        <property type="entry name" value="UBQ-activ_enz_E1_Cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000011">
        <property type="entry name" value="UBQ/SUMO-activ_enz_E1-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01408">
        <property type="entry name" value="Ube1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF4">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1 C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16191">
        <property type="entry name" value="E1_4HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16190">
        <property type="entry name" value="E1_FCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09358">
        <property type="entry name" value="E1_UFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10585">
        <property type="entry name" value="UBA_E1_SCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01849">
        <property type="entry name" value="UBIQUITINACT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00985">
        <property type="entry name" value="UBA_e1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00865">
        <property type="entry name" value="UBIQUITIN_ACTIVAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-activating enzyme E1 C-terminal" evidence="12">
        <location>
            <begin position="966"/>
            <end position="1104"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="686"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="9">
        <location>
            <position position="655"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG93562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1109" mass="128442" checksum="EEA93845A70FBCB8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRA6</accession>
    <name>A0A1J1GRA6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">60S ribosomal protein L27, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPL27</name>
        <name evidence="4" type="ORF">PGAL8A_00220100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527619.1">
        <property type="nucleotide sequence ID" value="XM_028670914.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRA6"/>
    <dbReference type="GeneID" id="39730728"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00220100"/>
    <dbReference type="OMA" id="NQWFFTK"/>
    <dbReference type="OrthoDB" id="2365484at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06090">
        <property type="entry name" value="KOW_RPL27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001141">
        <property type="entry name" value="Ribosomal_eL27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041991">
        <property type="entry name" value="Ribosomal_eL27_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038655">
        <property type="entry name" value="Ribosomal_eL27_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10497">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01777">
        <property type="entry name" value="Ribosomal_L27e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="146" mass="16893" checksum="76B19ED4F854B808" modified="2017-02-15" version="1">MGKLLKPGKVVIILNGRRAGKKAVVINTIETQTRERPYSYCLVAGIEKHPLRVTKKMPKRKIVKRSKVKAFIKYINVNHILPTRYQVANDFDIKSLASDEVLKSKNKKKEVKKLGKIFRDKFLEPINKKTGEVSKDISFLHKKLYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRF7</accession>
    <name>A0A1J1GRF7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA helicase, putative</fullName>
            <ecNumber evidence="7">3.6.4.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00133100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526448.1">
        <property type="nucleotide sequence ID" value="XM_028674859.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729856"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00133100"/>
    <dbReference type="OMA" id="TNRIHAY"/>
    <dbReference type="OrthoDB" id="2801544at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004520">
        <property type="term" value="F:DNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002711">
        <property type="entry name" value="HNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45766:SF3">
        <property type="entry name" value="DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45766">
        <property type="entry name" value="DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01844">
        <property type="entry name" value="HNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 7" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="586"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1140"/>
            <end position="1167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1497" mass="181260" checksum="71B0670855EA0F38" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRK9</accession>
    <name>A0A1J1GRK9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Exported protein 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">EXP2</name>
        <name evidence="3" type="ORF">PGAL8A_00230600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527723.1">
        <property type="nucleotide sequence ID" value="XM_028671029.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRK9"/>
    <dbReference type="GeneID" id="39730833"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00230600"/>
    <dbReference type="OMA" id="ECKNNFS"/>
    <dbReference type="OrthoDB" id="391739at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009618930" evidence="2">
        <location>
            <begin position="23"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="338" mass="38817" checksum="EB8CA2DB77AA18E6" modified="2017-02-15" version="1">MKISKIFIFSFVFLLYKNNNIAQCEGYGDIAATSAIQTIVKEPISLTIKDLYDHAVKDPVTRLINKIKKVLRYRKVLRWSRIWWILLVREIVGDNSIEKRTEKELREIWDQCTIAVFNNTLNTVETKPLLFLHGILNECKSNFSTKLRQDPSLIVAKMDQIIKSGIYRFWVSDAYLKIGRSGIFYKNITPKLVPALPKEHTLKYLSAYMVDKLKSLESKKNIESGKYEIDIGPDQEDKKDEATEKEDDLDQTVEPDETTNEDDNDETFNEDDINDETTNEDSSSSDLISEDGFDDDLIDGDNVEEGLIDEYNVDELDENEIDGILEGIDDEDNDGETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRN1</accession>
    <name>A0A1J1GRN1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00233100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527747.1">
        <property type="nucleotide sequence ID" value="XM_028671056.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRN1"/>
    <dbReference type="GeneID" id="39730858"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00233100"/>
    <dbReference type="OrthoDB" id="372892at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="622" mass="72610" checksum="68B80F1A7C935793" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRU8</accession>
    <name>A0A1J1GRU8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Inner centromere protein ARK-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00240300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527819.1">
        <property type="nucleotide sequence ID" value="XM_028671137.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730931"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00240300"/>
    <dbReference type="OMA" id="SSYYAWN"/>
    <dbReference type="OrthoDB" id="377103at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="732"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1859"/>
            <end position="1934"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2091"/>
            <end position="2118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2146"/>
            <end position="2170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1891"/>
            <end position="1931"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2092"/>
            <end position="2113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2148"/>
            <end position="2159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2160"/>
            <end position="2170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2187" mass="257852" checksum="8E625DAC79F8DF53" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRW3</accession>
    <name>A0A1J1GRW3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00264500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528052.1">
        <property type="nucleotide sequence ID" value="XM_028671395.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRW3"/>
    <dbReference type="GeneID" id="39731174"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00264500"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="139"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="163" mass="19115" checksum="F05D7E202FCFD752" modified="2017-02-15" version="1">MNFEKEKDNNKKKKNSNKSERLEEKCVNEEKNNINDATSDISLLLSLNNYNEYNVKKKKKKIEEFNIKKERKKKDNVSSSECILSDELKQENTKKIDSQISNTSNEKLNIKKEKGEFDDMELCVNNKKKEKKKKKEKNNILKAIIAFFFIKLLTICNKGNACI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS12</accession>
    <name>A0A1J1GS12_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00005400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528100.1">
        <property type="nucleotide sequence ID" value="XM_028671449.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS12"/>
    <dbReference type="GeneID" id="39728576"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00005400"/>
    <dbReference type="OrthoDB" id="337525at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1092"/>
            <end position="1119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1150" mass="137395" checksum="6EA4A8432861F969" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS39</accession>
    <name>A0A1J1GS39_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fam-i protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00264900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528055.1">
        <property type="nucleotide sequence ID" value="XM_028671398.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS39"/>
    <dbReference type="GeneID" id="39731178"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00264900"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="121"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="178"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="234" mass="28201" checksum="0372624A8E9B8FB2" modified="2017-02-15" version="1">MDLNLSDIICIDSCETLNEGDSTASCTHREIKDETVSTPENPLHDDLNSRDAILNQSEDINLDSVTSKNLLHKMSLSIFQLVIIFIFFLRFKKIYSRKLKAKNEMNVRLQKILDNSNKMVKDDLEKEMQEEKRKMEDGQKELLKKKKEMEYWGKEVLRHREEWERTLKEKQVCDKSMQKELEERAKRITEEREKWKKRILIDKMELEKKMRKNKEEGEERMLKVIEKFEKEMLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSC4</accession>
    <name>A0A1J1GSC4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00012800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528170.1">
        <property type="nucleotide sequence ID" value="XM_028671526.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSC4"/>
    <dbReference type="GeneID" id="39728650"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00012800"/>
    <dbReference type="OMA" id="QQRDDTP"/>
    <dbReference type="OrthoDB" id="378788at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="382"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="492"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="57"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="393"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="517"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="537"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="570"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="586"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="601"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="625"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="638"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="665"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="687"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="721"/>
            <end position="809"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="815" mass="97073" checksum="59B5F6BDDF70F68A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSD6</accession>
    <name>A0A1J1GSD6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Survival motor neuron-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SMN</name>
        <name evidence="3" type="ORF">PGAL8A_00392800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527045.1">
        <property type="nucleotide sequence ID" value="XM_028670276.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSD6"/>
    <dbReference type="GeneID" id="39732458"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00392800"/>
    <dbReference type="OMA" id="IGRTCSF"/>
    <dbReference type="OrthoDB" id="79171at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002999">
        <property type="entry name" value="Tudor"/>
    </dbReference>
    <dbReference type="SMART" id="SM00333">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50304">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tudor" evidence="2">
        <location>
            <begin position="159"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="235"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="317" mass="37696" checksum="436B33DA287C757B" modified="2017-02-15" version="1">MDDFNETLEGLEEKISEYEKQLTLVRDEIKKYEQIEDQENEQLKNLKKLECDMLEVINLTRDLIKYKKQNEIENDEANELEKNEENQIQNINENITESNGLIGRTCSFIYENKKIYGLIENLIVEKNVKQLIVHIFETNEKITIPKDYVHLNEILDESALSENNQFQALYKKDGHWYDCIISKSKGDSYLITYIGYNNSEYVKNDQVRIKKKKKIKEIITPAGYKIPENLIIKENDSLKVKMKKKKKRIALKKKQKNELINKEFANKTQQWRSFHEKALSKSKHLLIAHKKVENIENNNNPSNFNIRRKFDYNDNDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSH8</accession>
    <name>A0A1J1GSH8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00267880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000037">
        <property type="protein sequence ID" value="CRG95476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528286.1">
        <property type="nucleotide sequence ID" value="XM_028671656.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSH8"/>
    <dbReference type="GeneID" id="39731208"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00267880"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="59" mass="7102" checksum="704DEB485B884566" modified="2017-02-15" version="1" fragment="single">MKTLILFLKITTFLLLIWMYLCFHKCYSYKTLIDKNILQIKNELKYERVLTEGDIAGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSL9</accession>
    <name>A0A1J1GSL9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00175000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526864.1">
        <property type="nucleotide sequence ID" value="XM_028670075.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSL9"/>
    <dbReference type="GeneID" id="39730277"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00175000"/>
    <dbReference type="OMA" id="LNYFHYN"/>
    <dbReference type="OrthoDB" id="392563at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="287"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="787" mass="95806" checksum="9861ED54B89298C0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSM8</accession>
    <name>A0A1J1GSM8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00175800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526872.1">
        <property type="nucleotide sequence ID" value="XM_028670084.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSM8"/>
    <dbReference type="GeneID" id="39730285"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00175800"/>
    <dbReference type="OMA" id="QKNANND"/>
    <dbReference type="OrthoDB" id="381252at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="405" mass="48083" checksum="28214A8D80AD11D0" modified="2017-02-15" version="1">MKSHLFSCNSRYYYDILNITLSDDEEFERFLDTNKKNELYYFFEKAVNKIIIDTKKSCDISSDFEEVEKLEYKKNEVVDSDCIDDIDIILQKSKCKNMFLKKYKNDNIIKLPPKSIKQRIYSVNQEKAEMKHNKRDQNKNDKIIENFKNVLCNDLNKYFKDILENVKKNNETHNQSNNYIKNAIHTLNDSIKINSINALKDNIKDCVINCNNNKHINYFFKDNTKNLNYNNIYANENIYDDNGIIKVDRCERNGYINKKNFKENNYNINLDTNTKHNQNNVLKKKTYKKRKTSKKKKSVKNFHFSKKKVSTKENKFNPYHFNNFYSLKNSKPKNILTNNQNIETLNCSNISLNQLICNNDKLNIFKNLRNSVEAKDSSCGNSNEDFTFNHFQKNANNNILNKLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSQ8</accession>
    <name>A0A1J1GSQ8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Protein transport protein SEC31, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">SEC31</name>
        <name evidence="11" type="ORF">PGAL8A_00404800</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat SEC31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527165.1">
        <property type="nucleotide sequence ID" value="XM_028670409.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732578"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00404800"/>
    <dbReference type="OMA" id="WLERPCG"/>
    <dbReference type="OrthoDB" id="542917at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030127">
        <property type="term" value="C:COPII vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090110">
        <property type="term" value="P:COPII-coated vesicle cargo loading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007029">
        <property type="term" value="P:endoplasmic reticulum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.940.10">
        <property type="entry name" value="Functional domain of the splicing factor Prp18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024298">
        <property type="entry name" value="Sec16_Sec23-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040251">
        <property type="entry name" value="SEC31-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13923">
        <property type="entry name" value="SEC31-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13923:SF11">
        <property type="entry name" value="SECRETORY 31, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12931">
        <property type="entry name" value="TPR_Sec16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Sec16 Sec23-binding" evidence="10">
        <location>
            <begin position="642"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="592"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="592"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="620"/>
            <end position="629"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG94344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1329" mass="151485" checksum="F15290B9F885F5ED" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GST5</accession>
    <name>A0A1J1GST5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00279500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528406.1">
        <property type="nucleotide sequence ID" value="XM_028671789.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731328"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00279500"/>
    <dbReference type="OrthoDB" id="377458at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="799"/>
            <end position="855"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1823" mass="215742" checksum="5961389B52BCE06A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT02</accession>
    <name>A0A1J1GT02_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00286700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528478.1">
        <property type="nucleotide sequence ID" value="XM_028671869.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT02"/>
    <dbReference type="GeneID" id="39731400"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00286700"/>
    <dbReference type="OMA" id="TLIEWFL"/>
    <dbReference type="OrthoDB" id="365655at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="546" mass="63763" checksum="C9076CAE59D4C843" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT36</accession>
    <name>A0A1J1GT36_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Methionine aminopeptidase</fullName>
            <ecNumber evidence="10">3.4.11.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">METAP1b</name>
        <name evidence="13" type="ORF">PGAL8A_00391500</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 10">Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 10">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="10">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="8">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with zinc, cobalt, manganese or divalent iron ions. Has high activity with zinc; zinc cofactor is transferred into the active site region by the ZNG1 zinc chaperone.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Associates with the 60S ribosomal subunit of the 80S translational complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="10"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527032.1">
        <property type="nucleotide sequence ID" value="XM_028670262.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT36"/>
    <dbReference type="GeneID" id="39732445"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00391500"/>
    <dbReference type="OMA" id="CAMGREV"/>
    <dbReference type="OrthoDB" id="3209743at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004239">
        <property type="term" value="F:initiator methionyl aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01086">
        <property type="entry name" value="MetAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01974">
        <property type="entry name" value="MetAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002467">
        <property type="entry name" value="Pept_M24A_MAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031615">
        <property type="entry name" value="Zfn-C6H2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00500">
        <property type="entry name" value="met_pdase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43330">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43330:SF7">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15801">
        <property type="entry name" value="zf-C6H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00680">
        <property type="entry name" value="MAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52013">
        <property type="entry name" value="ZF_C6H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 8 10" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 8 10" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C6H2-type" evidence="12">
        <location>
            <begin position="131"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="65"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="78"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="339"/>
        </location>
        <ligand>
            <name>a protein</name>
            <dbReference type="ChEBI" id="CHEBI:16541"/>
        </ligand>
        <ligandPart>
            <name>N-terminal L-methionine residue</name>
            <dbReference type="ChEBI" id="CHEBI:64731"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="356"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="367"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>4</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="367"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="433"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>4</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="440"/>
        </location>
        <ligand>
            <name>a protein</name>
            <dbReference type="ChEBI" id="CHEBI:16541"/>
        </ligand>
        <ligandPart>
            <name>N-terminal L-methionine residue</name>
            <dbReference type="ChEBI" id="CHEBI:64731"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="466"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>4</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="497"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="497"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>4</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG94211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="531" mass="61456" checksum="9FC7EAF124863137" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT70</accession>
    <name>A0A1J1GT70_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00019300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528235.1">
        <property type="nucleotide sequence ID" value="XM_028671598.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT70"/>
    <dbReference type="GeneID" id="39728715"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00019300"/>
    <dbReference type="OMA" id="HIEDNEN"/>
    <dbReference type="OrthoDB" id="387608at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="683"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="730"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="271"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="737"/>
            <end position="795"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="848" mass="101840" checksum="F298CB97DB4FD24B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT73</accession>
    <name>A0A1J1GT73_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PGAL8A_00395500</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">P-body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527072.1">
        <property type="nucleotide sequence ID" value="XM_028670306.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT73"/>
    <dbReference type="GeneID" id="39732485"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00395500"/>
    <dbReference type="OMA" id="PRDHQMI"/>
    <dbReference type="OrthoDB" id="10265785at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17940">
        <property type="entry name" value="DEADc_DDX6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000114">
        <property type="entry name" value="ATP-dependent RNA helicase DDX6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000364">
        <property type="entry name" value="ATP-dependent RNA helicase DDX6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47960">
        <property type="entry name" value="DEAD-BOX ATP-DEPENDENT RNA HELICASE 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 12 16" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 12 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="15">
        <location>
            <begin position="58"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="89"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="269"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="11">
        <location>
            <begin position="58"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="CRG94251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="431" mass="49240" checksum="3358D1FA0490C7F1" modified="2017-02-15" version="1">MNYQTNCTATNSNAMNNSNSLNKIDENVIFDEAWKKRVLEPLKDRRYKTEDVTKTKGNEFEDYFLKRELLMGIFEKGYEKPSPIQEESIPVALAGKNILARAKNGTGKTAAFAIPLLEKCNTHKNFIQGLILVPTRELALQTSAMIKELGKHMKVQCMVTTGGTSLREDIMRLYNVVHILCGTPGRILDLANKDVANLSGCHIMVMDEADKLLSPEFQPIVEELMKFLPKEKQILMYSATFPVTVKEFRAIYLSDAHEINLMDELTLKGITQYYAFVKERQKVHCLNTLFAKLQINQAIIFCNSITRVELLAKKITELGYSSFYIHARMSQTHRNRVFHDFRNGACRCLVSSDLFTRGIDIQSVNVVINFDFPKNSETYLHRIGRSGRYGHLGLAINLITYEDRFNLYKIEIELGTEIQPIPNEIDPSLYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT80</accession>
    <name>A0A1J1GT80_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00285200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528463.1">
        <property type="nucleotide sequence ID" value="XM_028671851.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT80"/>
    <dbReference type="GeneID" id="39731385"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00285200"/>
    <dbReference type="OMA" id="HYYLNEN"/>
    <dbReference type="OrthoDB" id="386907at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="286"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="520"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="390"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="784"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="526"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="877" mass="105325" checksum="039405936A066440" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT83</accession>
    <name>A0A1J1GT83_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00270500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000040">
        <property type="protein sequence ID" value="CRG95504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528313.1">
        <property type="nucleotide sequence ID" value="XM_028671685.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT83"/>
    <dbReference type="GeneID" id="39731236"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00270500"/>
    <dbReference type="OMA" id="PRHECAT"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="653"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1148"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="364"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="541"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="780"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="419"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="463"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="544"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="780"/>
            <end position="803"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1190" mass="137428" checksum="3B80B81152F101FE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTH6</accession>
    <name>A0A1J1GTH6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcription factor with AP2 domain(S), putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AP2-G2</name>
        <name evidence="2" type="ORF">PGAL8A_00279800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528409.1">
        <property type="nucleotide sequence ID" value="XM_028671792.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731331"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00279800"/>
    <dbReference type="OrthoDB" id="392898at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2050">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="414"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="938"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="985"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1366"/>
            <end position="1387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="424"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="444"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="946"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="965"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="991"/>
            <end position="1004"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1508" mass="176252" checksum="1E52358618056C83" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTK9</accession>
    <name>A0A1J1GTK9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Plastid replication-repair enzyme, putative</fullName>
            <ecNumber evidence="5">2.7.7.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">PREX</name>
        <name evidence="5" type="ORF">PGAL8A_00283000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528441.1">
        <property type="nucleotide sequence ID" value="XM_028671827.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731363"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00283000"/>
    <dbReference type="OrthoDB" id="275278at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08639">
        <property type="entry name" value="DNA_pol_A_Aquificae_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01029">
        <property type="entry name" value="TOPRIM_primases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01122">
        <property type="entry name" value="Twinkle_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001177">
        <property type="entry name" value="Plastid replication-repair enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1360.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1060.10">
        <property type="entry name" value="Taq DNA Polymerase, Chain T, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001098">
        <property type="entry name" value="DNA-dir_DNA_pol_A_palm_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007694">
        <property type="entry name" value="DNA_helicase_DnaB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002298">
        <property type="entry name" value="DNA_polymerase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034154">
        <property type="entry name" value="TOPRIM_DnaG/twinkle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027032">
        <property type="entry name" value="Twinkle-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12873">
        <property type="entry name" value="T7-LIKE MITOCHONDRIAL DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12873:SF0">
        <property type="entry name" value="TWINKLE MTDNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13481">
        <property type="entry name" value="AAA_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00476">
        <property type="entry name" value="DNA_pol_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00868">
        <property type="entry name" value="DNAPOLI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00474">
        <property type="entry name" value="35EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00482">
        <property type="entry name" value="POLAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56731">
        <property type="entry name" value="DNA primase core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51199">
        <property type="entry name" value="SF4_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="domain" description="SF4 helicase" evidence="4">
        <location>
            <begin position="563"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="429"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1429"/>
            <end position="1512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="429"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="453"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1834" mass="215856" checksum="2B273E8BFA745E82" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTT8</accession>
    <name>A0A1J1GTT8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Aspartate aminotransferase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00185400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000024">
        <property type="protein sequence ID" value="CRG94459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527280.1">
        <property type="nucleotide sequence ID" value="XM_028670538.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTT8"/>
    <dbReference type="GeneID" id="39730381"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00185400"/>
    <dbReference type="OMA" id="GTWTHIT"/>
    <dbReference type="OrthoDB" id="6752799at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004069">
        <property type="term" value="F:L-aspartate:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000796">
        <property type="entry name" value="Asp_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11879:SF22">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="7">
        <location>
            <begin position="30"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="405" mass="46910" checksum="FE03C17DB3482C89" modified="2017-02-15" version="1">MDKALLNLKAAQGDIILETALDFIKDKSPKKINLSFGAIIAEDGNYYSFESVNEAEKIVIERYKDKPYIFSNGTKEFSILTQELLFGKNSKYMKEKRICTIQTIGGDGSIFLAIKFLKSLNIKSIYVTNSYYVTHVTMIKACDLTPKYLNFFDTNLMDINYDMFLNDLKSIEDRSCIILQTFACNPCSVNIKEEYFEEIIDIFLKKKHIVVFDVAYLCFGNSDLDKDTLLIRKFEERGIAFIVCQTFSKCMAIYGSRAGVLHIICENKSQRQTVANNLCSIAEASYGTPSVHVNRVICELLKNEKLKSSWIKDLCELSKCINNKRILFLEKLEFYQKKYNLKYQWNEYKKQRGIFVYIPLIGKIFQKLRFYHIYIINSGRINISGITRDNVDYIADIICRCLSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTZ7</accession>
    <name>A0A1J1GTZ7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH OST-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00291900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528523.1">
        <property type="nucleotide sequence ID" value="XM_028671918.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731452"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00291900"/>
    <dbReference type="OMA" id="CDNNGCD"/>
    <dbReference type="OrthoDB" id="447390at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056022">
        <property type="entry name" value="DUF7602"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025677">
        <property type="entry name" value="OST-HTH-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025605">
        <property type="entry name" value="OST-HTH/LOTUS_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24549">
        <property type="entry name" value="DUF7602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14418">
        <property type="entry name" value="OHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51644">
        <property type="entry name" value="HTH_OST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH OST-type" evidence="2">
        <location>
            <begin position="1417"/>
            <end position="1492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="512"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1492" mass="176659" checksum="7F8646025EE1F2A9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU50</accession>
    <name>A0A1J1GU50_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00327000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000053">
        <property type="protein sequence ID" value="CRG96054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528862.1">
        <property type="nucleotide sequence ID" value="XM_028672295.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU50"/>
    <dbReference type="GeneID" id="39731800"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00327000"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="367" mass="43553" checksum="502C1DED6D12886F" modified="2017-02-15" version="1">MKTLTLFLRITTFHLLIWMYQCFYNCYSYKTWIDENILQTKNELKYERILTEGNTEEKKQTNAEGCLKERPLDNEKNKRENPVQNENPCDRWQRKTNPLLRKIFDKDTSKMDPKWREQKWNNEWNKISANKLNELSSIFHRSDISEEEKKKLIRNVKDELDTEFAKFLVECKKEMSDNKAESKSKKEMIDNKTESESRIEMTDNITESESIKGMIQNKTESEYNIEITDNKSKSASMKEMTDNKTESESMKMMIDNKTESESKIEMTDNKTESESKIEMTDNKKEAKSRIEMTDNKTESESIKGMIENKTESESKIEMTDNKTESVSRIEMTDNKTESESKNEKGKNKIKNKKSNILKFLFKRFDNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU53</accession>
    <name>A0A1J1GU53_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Voltage-dependent anion-selective channel protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00303700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528633.1">
        <property type="nucleotide sequence ID" value="XM_028672040.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU53"/>
    <dbReference type="GeneID" id="39731570"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00303700"/>
    <dbReference type="OMA" id="FPHANKF"/>
    <dbReference type="OrthoDB" id="7827681at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008308">
        <property type="term" value="F:voltage-gated monoatomic anion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="entry name" value="Porin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001925">
        <property type="entry name" value="Porin_Euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027246">
        <property type="entry name" value="Porin_Euk/Tom40"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11743:SF70">
        <property type="entry name" value="GH26960P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11743">
        <property type="entry name" value="VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01459">
        <property type="entry name" value="Porin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="289" mass="33237" checksum="89957826334F57B1" modified="2017-02-15" version="1">MDFPKLLNKPSIDLLKNDFPHSSKFELEHTSISKYPFLKSGLSFSNNIYSVYTSFKNSIYDTKNEIKFDNTGVNFLDIKYQPSFIKNVNVCGKYMKNNGKADDSFEIYTEYNTEDTNIFSSINVRNLFFKYMHVYSHPKYSNFKCGGLIQGNLDIKNLQYSFGGAYTKNHNDNHYIFSLRSIPSNKHLCGSLAFNLYFQNKNINDNAVSIEVIQNFIEKKANINVASVWFVNNKNTFIKTKISNDTKVALSLTHKYNEFVTVTLGSQIDISKISLPDNTKFGVKLYLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUC5</accession>
    <name>A0A1J1GUC5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CCR4-associated factor 16, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CAF16</name>
        <name evidence="4" type="ORF">PGAL8A_00305500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528651.1">
        <property type="nucleotide sequence ID" value="XM_028672060.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUC5"/>
    <dbReference type="GeneID" id="39731588"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00305500"/>
    <dbReference type="OMA" id="YLGTEWV"/>
    <dbReference type="OrthoDB" id="6512918at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002144">
        <property type="entry name" value="CCR4-associated factor 16, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43158">
        <property type="entry name" value="SKFA PEPTIDE EXPORT ATP-BINDING PROTEIN SKFE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43158:SF2">
        <property type="entry name" value="SKFA PEPTIDE EXPORT ATP-BINDING PROTEIN SKFE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="3">
        <location>
            <begin position="6"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="257" mass="30124" checksum="6C0C440985F78883" modified="2017-02-15" version="1">MNEIIINNLNYNYYNRIKNTSIKALVNVNLSFQRGMRILVCGKNGAGKSTLLSIIAGKKLIKEEEVLIFNKPAFHDTTLSNKIGFVGEWWSDEYVLNITIKDLFSQYRHSKRYKNLLKLFEINENKLITSISKGEKKKVQILANIIKRKDIYIFDEVTESLDLVSRKLLLEFLKKECIKYNCIIIYSTHIFDHMDKWCTHILYLSNGYVAHFSDIKTVLNDNNYMSLAEYIFNKMLKELKDKENINDLDDLLLIDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUH6</accession>
    <name>A0A1J1GUH6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Actin-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ALP1</name>
        <name evidence="6" type="ORF">PGAL8A_00337700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528964.1">
        <property type="nucleotide sequence ID" value="XM_028672408.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUH6"/>
    <dbReference type="GeneID" id="39731907"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00337700"/>
    <dbReference type="OMA" id="IDHGHIS"/>
    <dbReference type="OrthoDB" id="5132116at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000050">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00432">
        <property type="entry name" value="ACTINS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="378" mass="42763" checksum="9F091F0C7997599F" modified="2017-02-15" version="1">MDNQTIIIDNGSGYIKAGLNAYEEPSIIFPTLIGNLRHNENPETFVGDDAIYHESELSIYRPIDHGHISDWDMAQKIWDYTLNCIDKNKNAKDILLTEPPLCSTSHRTKMGEMFFEYFDFLNLNISVSGLMSIYAAGLTTGLVLDVGEGVTQCLPIFDGYIEKNSVIRSDFGGEELSMFLQKLICDIGYSMTTRKNFEYVKSIKENLCFCSLNPSQDQLRDDLSVTYTLPDGDVLRDGYDTIEISHERFYVPEALFNPQLCHRDSLSIVDIIWKSILLCPIENRKSLSSCIVLSGGSTLFPNLVERIETEVKNNAPANARSAVKVYAHEKRAVMAWCGSRIFSQPELRQAQQGLWISKDEYDEIGENIFLIKATLKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUM9</accession>
    <name>A0A1J1GUM9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00322200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000049">
        <property type="protein sequence ID" value="CRG96009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528817.1">
        <property type="nucleotide sequence ID" value="XM_028672246.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUM9"/>
    <dbReference type="GeneID" id="39731755"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00322200"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="112" mass="13232" checksum="BECB34E5EF633CB1" modified="2017-02-15" version="1" fragment="single">KSLINRDTLQAKIGLKHERMLAEADISEKKSSYIRKRVEEYPSGEMNIGNNELIHLMDMYLKCYNANSMATYVEVLFKVENEMRYKCRDKILNAYRNNISYEIEIEKLSLTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUN0</accession>
    <name>A0A1J1GUN0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phosphoglycerate mutase</fullName>
            <ecNumber evidence="8">5.4.2.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00346700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate</text>
            <dbReference type="Rhea" id="RHEA:15901"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="EC" id="5.4.2.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.11" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529054.1">
        <property type="nucleotide sequence ID" value="XM_028672508.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUN0"/>
    <dbReference type="GeneID" id="39731997"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00346700"/>
    <dbReference type="OMA" id="MLPYWYD"/>
    <dbReference type="OrthoDB" id="354304at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004619">
        <property type="term" value="F:phosphoglycerate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1240:FF:000003">
        <property type="entry name" value="2,3-bisphosphoglycerate-dependent phosphoglycerate mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01039">
        <property type="entry name" value="PGAM_GpmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005952">
        <property type="entry name" value="Phosphogly_mut1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01258">
        <property type="entry name" value="pgm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010713">
        <property type="entry name" value="PRK14115.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11931">
        <property type="entry name" value="PHOSPHOGLYCERATE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="4 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="5">
        <location>
            <position position="10"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="5">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="9"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="22"/>
            <end position="23"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="88"/>
            <end position="91"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="115"/>
            <end position="116"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="184"/>
            <end position="185"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG96249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="249" mass="28735" checksum="E902DFC123B78EFE" modified="2017-02-15" version="1">MVYTLVLLRHGESTWNKENKFTGWTDVPLSEKGEEEAISAGNYLKEKNFKFDVVYTSVLKRAIHTTWNVLKTADLLHVPVIKTWRLNERHYGSLQGLNKSETAKKYGEEQVKIWRRSYDIPPPKLDKEDSRWPGHNIVYKNVPKDTLPFTECLKDTVERVLPFWFDHIAPDILANKKVLVSAHGNSLRGLVKHLDSLSEADVLELNIPTGVPLVYELDENLKPIKHYYLLDSEELKKKMDEVANQGKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUS3</accession>
    <name>A0A1J1GUS3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00348100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529068.1">
        <property type="nucleotide sequence ID" value="XM_028672524.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUS3"/>
    <dbReference type="GeneID" id="39732011"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00348100"/>
    <dbReference type="OrthoDB" id="375908at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="492" mass="59691" checksum="B58E00B6797FBED5" modified="2017-02-15" version="1">MPSGSFFFKVFICGSPFCVLFFNEINRIRKFRENERLNKSLFLKNFDKNIIKNEENNEKLKKHSLFINDENENEALHYFYGKAWGYTTDYEIDLSLNTGDLIFIKHDLDYINFFKKILLKINRYLQSNDNYDEIGIIIKKHNISYVYIQNILNKKEKLMRYSYFLQKYKPSVVSLRRLLCNDEDIKKKLHENILENIKRNEINKYSIFFNILYNILKKKKKINKELSKNDCLCDEYICKKINSNIEVSNLINMFLFRSFNLFFYFMTYINEENLKRESHEKNVLLKNINSNNTILLNNSRLCKSFLHFYELPLNSLTQFPFIKKDYELMKKNNFIYEKPNRSVQKEIEKFISLLIENEHTLIDSFEYINKTLKKEKKEEKEINKYKNSIYSNYFTDNLRFYFESFFELKKFSLANYHVYEIYKSTHLLPSIKNYNSLSLFLCLNNLCKPLNPHNLLHDTFSIPKLSNIFHVRQEEDEKLQKYFYQFNKVPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUT8</accession>
    <name>A0A1J1GUT8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">U3 small nucleolar ribonucleoprotein protein IMP3, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">IMP3</name>
        <name evidence="10" type="ORF">PGAL8A_00220600</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uS4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527624.1">
        <property type="nucleotide sequence ID" value="XM_028670919.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUT8"/>
    <dbReference type="GeneID" id="39730733"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00220600"/>
    <dbReference type="OMA" id="FRIKHEQ"/>
    <dbReference type="OrthoDB" id="10248812at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034457">
        <property type="term" value="C:Mpp10 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="entry name" value="RNA-binding S4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022801">
        <property type="entry name" value="Ribosomal_uS4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001912">
        <property type="entry name" value="Ribosomal_uS4_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831">
        <property type="entry name" value="30S 40S RIBOSOMAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831:SF1">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00163">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01390">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55174">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS4 N-terminal" evidence="9">
        <location>
            <begin position="3"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="RNA-binding S4" evidence="8">
        <location>
            <begin position="107"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG94809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="183" mass="22031" checksum="25324E9FE1C91B0F" modified="2017-02-15" version="1">MRKLKYHEQKLLKKVNLYDWKRTRNIREVKILRKYVIQNREDYTKYNKICGYITKLVSKLRLLPENDEFRIKMTDELLDKLYDMGLINYKSSLAECEKISVSSFCRRRLAVMLFRLKFVQTIQLAITYIQHGNIRVGNNVINNPSFHINRNLEDHIKWADGSKIIKHIQKHQENKDDYELLGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUU5</accession>
    <name>A0A1J1GUU5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">tRNA nucleotidyltransferase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00347100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529058.1">
        <property type="nucleotide sequence ID" value="XM_028672513.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUU5"/>
    <dbReference type="GeneID" id="39732001"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00347100"/>
    <dbReference type="OMA" id="IRCIRFC"/>
    <dbReference type="OrthoDB" id="445712at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052929">
        <property type="term" value="F:ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052927">
        <property type="term" value="F:CC tRNA cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001680">
        <property type="term" value="P:tRNA 3'-terminal CCA addition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05398">
        <property type="entry name" value="NT_ClassII-CCAase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.460.10:FF:000040">
        <property type="entry name" value="tRNA nucleotidyltransferase cca1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3090.10">
        <property type="entry name" value="cca-adding enzyme, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002646">
        <property type="entry name" value="PolA_pol_head_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13734:SF5">
        <property type="entry name" value="CCA TRNA NUCLEOTIDYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13734">
        <property type="entry name" value="TRNA-NUCLEOTIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01743">
        <property type="entry name" value="PolyA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81891">
        <property type="entry name" value="Poly A polymerase C-terminal region-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012430211" evidence="5">
        <location>
            <begin position="20"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="domain" description="Poly A polymerase head" evidence="6">
        <location>
            <begin position="153"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="713" mass="85754" checksum="5801C6142CED44D8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV01</accession>
    <name>A0A1J1GV01_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00356100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529148.1">
        <property type="nucleotide sequence ID" value="XM_028672613.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732091"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00356100"/>
    <dbReference type="OMA" id="CDNIFFL"/>
    <dbReference type="OrthoDB" id="382408at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277">
        <property type="entry name" value="ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277:SF81">
        <property type="entry name" value="PROTEIN ABHD13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1406"/>
            <end position="1436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1409"/>
            <end position="1436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2011" mass="240806" checksum="8B86728BEAFAA862" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV02</accession>
    <name>A0A1J1GV02_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DEAD/DEAH box helicase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00333900</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528929.1">
        <property type="nucleotide sequence ID" value="XM_028672370.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV02"/>
    <dbReference type="GeneID" id="39731869"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00333900"/>
    <dbReference type="OMA" id="DTKNVDH"/>
    <dbReference type="OrthoDB" id="432247at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="765"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="49"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1034"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="49"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1034"/>
            <end position="1049"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1194" mass="142079" checksum="27AAA7ACCE543A1D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVC3</accession>
    <name>A0A1J1GVC3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">AAA family ATPase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00367000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family. PCH2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529250.1">
        <property type="nucleotide sequence ID" value="XM_028672726.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVC3"/>
    <dbReference type="GeneID" id="39732200"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00367000"/>
    <dbReference type="OMA" id="CRYEIYK"/>
    <dbReference type="OrthoDB" id="10042665at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051598">
        <property type="term" value="P:meiotic recombination checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001527">
        <property type="entry name" value="AAA family ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044539">
        <property type="entry name" value="Pch2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058249">
        <property type="entry name" value="Pch2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45991">
        <property type="entry name" value="PACHYTENE CHECKPOINT PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45991:SF1">
        <property type="entry name" value="PACHYTENE CHECKPOINT PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23242">
        <property type="entry name" value="AAA_lid_TRIP13_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0469">Meiosis</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="296"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="579" mass="67458" checksum="FD1421FD80DDDAF8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVE2</accession>
    <name>A0A1J1GVE2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">UVB-resistance protein UVR8 homologue, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00365100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529231.1">
        <property type="nucleotide sequence ID" value="XM_028672705.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVE2"/>
    <dbReference type="GeneID" id="39732181"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00365100"/>
    <dbReference type="OMA" id="WRWGCSG"/>
    <dbReference type="OrthoDB" id="10256179at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058923">
        <property type="entry name" value="RCC1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051210">
        <property type="entry name" value="Ub_ligase/GEF_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22870">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22870:SF360">
        <property type="entry name" value="ULTRAVIOLET-B RECEPTOR UVR8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25390">
        <property type="entry name" value="WD40_RLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="RCC1-like" evidence="3">
        <location>
            <begin position="38"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="87"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="145"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="204"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="258"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="367"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="422" mass="47806" checksum="5911E4C47A3BDB8F" modified="2017-02-15" version="1">MLKICKRLKEKNFYLKYDVKFFSNKTNVEEKEKKYNLWRWGCTGDSIFSSVKVGEKNKLPEKISNFENSNIEKLSAGCNHAAFIVDGKIFTYGLNDKGQLGRQLDENEKQKNYSLIPKEVNISNNVKFKNVCCGFKHTLAIDENNDLYSWGWGGNFFKGANGLGQGNKENIIYPKKVESFKNEDTEFVDICCGDQHSLVLTKNGKVYGCGRGEFGRLGRGNHGDQLFFEEIEFFTSNNIIIKNICCGHSFSAALSVNGELYVWGRNDYGQLGIENSIGDLYSHEVYPNKVKYFEIENVKIKLIACGDNHMIACSENNIIYFWGARAWLEPKAITLNPKYENSVIKSDIEKIDAGGSSYYYSMLLSDNKLYSWGKHNSSCLALGDKKNHNEPTLVDSKLFNDEKVCDISCGRGRVLAKTLANN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVV0</accession>
    <name>A0A1J1GVV0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ubiquitin specific protease, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00417100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529394.1">
        <property type="nucleotide sequence ID" value="XM_028672886.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732702"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00417100"/>
    <dbReference type="OMA" id="NEQQDCH"/>
    <dbReference type="OrthoDB" id="420187at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2230.10">
        <property type="entry name" value="DUSP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035927">
        <property type="entry name" value="DUSP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006615">
        <property type="entry name" value="Pept_C19_DUSP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050185">
        <property type="entry name" value="Ub_carboxyl-term_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646:SF46">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06337">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143791">
        <property type="entry name" value="DUSP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51283">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUSP" evidence="4">
        <location>
            <begin position="396"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="3">
        <location>
            <begin position="1265"/>
            <end position="1617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="782"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1156"/>
            <end position="1214"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="303"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="782"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="905"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1156"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1167"/>
            <end position="1214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1617" mass="191329" checksum="7D097353577BD04D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVZ4</accession>
    <name>A0A1J1GVZ4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00371700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529297.1">
        <property type="nucleotide sequence ID" value="XM_028672779.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVZ4"/>
    <dbReference type="GeneID" id="39732247"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00371700"/>
    <dbReference type="OMA" id="IMSIMNV"/>
    <dbReference type="OrthoDB" id="384054at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="114"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="286" mass="33719" checksum="1BE241BA1E0578AF" modified="2017-02-15" version="1">MGDIHNEKSDLEKNINEETKDSSDESSDSYYKNKFRFKKNSIEIKKKSLLKNKLKSDDIKIIKNDLHENNKILDNGEIFCLRSQNENEKNENLEKIIKIGTKNSTMDKKNKSSITFANDKKEKYKEENQQINENANEIQIKIEKEQKYKDEINHDKNDNEIKSTNFNNEKKSFNYYSNNIKEKINSQNDTPNEKNCELFDSENINTKINKKLKKIKMIKEKKKNEELSTLNLIKKHGRLVNKIEEIYINNSEEIENMRNDFTSLKNDLNKLMSIINIGQKAVALLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWG1</accession>
    <name>A0A1J1GWG1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00418000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529403.1">
        <property type="nucleotide sequence ID" value="XM_028672896.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWG1"/>
    <dbReference type="GeneID" id="39732711"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00418000"/>
    <dbReference type="OrthoDB" id="368498at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="237" mass="29008" checksum="DF475645DD3F50AB" modified="2017-02-15" version="1">MYESGNKYMFDVKRCIRIYRFCLILHLILAILQLFTPRPFLFIAHLAVFFIGIDCFCSYLTFKYFCFTVVNMICGISDFIWLLFKCIGKNRFKWLDPKYYWKIINIDNIFLQFFSTSLHYMFDEKKNYETPQNMQKKYEYIKNFFKLLPVQKKICVWKIYIELFIIIVGIFLYFMGSYISWQLYKYTLNYNQNDLLFHNYHYGTFHEDNNQNSPSSQNDFIPFIGQPYRISDFLEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX33</accession>
    <name>A0A1J1GX33_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00445100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529673.1">
        <property type="nucleotide sequence ID" value="XM_028673195.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX33"/>
    <dbReference type="GeneID" id="39732984"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00445100"/>
    <dbReference type="OrthoDB" id="391627at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="101" mass="11156" checksum="1FFB576805842FFD" modified="2017-02-15" version="1">MALKKIYNGHFRRIPSCEKIEKRFSTDKNVEKSNENQNSEKKVDYGIVDNIIYGAGIGVGAVGLALAIISSTVIASTLLFSTYFCVNTCNAKEEEIIDGYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX51</accession>
    <name>A0A1J1GX51_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cell cycle control protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00460000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529823.1">
        <property type="nucleotide sequence ID" value="XM_028673363.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733133"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00460000"/>
    <dbReference type="OMA" id="YIEPFEE"/>
    <dbReference type="OrthoDB" id="1924287at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050781">
        <property type="entry name" value="CWC22_splicing_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003891">
        <property type="entry name" value="Initiation_fac_eIF4g_MI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003890">
        <property type="entry name" value="MIF4G-like_typ-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18034">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN CWF22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18034:SF3">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR CWC22 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02847">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00544">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00543">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51366">
        <property type="entry name" value="MI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MI" evidence="7">
        <location>
            <begin position="1241"/>
            <end position="1357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="214"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="323"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1151"/>
            <end position="1227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="77"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="224"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="323"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="386"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="410"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="444"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="490"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="564"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="608"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="653"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="685"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="757"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1151"/>
            <end position="1174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1181"/>
            <end position="1192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1193"/>
            <end position="1224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1436" mass="168017" checksum="ADA0D9990F5A375A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX59</accession>
    <name>A0A1J1GX59_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00447500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529697.1">
        <property type="nucleotide sequence ID" value="XM_028673223.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX59"/>
    <dbReference type="GeneID" id="39733008"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00447500"/>
    <dbReference type="OMA" id="SHNLYTT"/>
    <dbReference type="OrthoDB" id="10435920at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="146" mass="16967" checksum="78D9880F1DF505D1" modified="2017-02-15" version="1">MDAQNFLRVLTVATSVSFLLSSLILLLSHNLYTTFILGFYGTLLSILILLFEYYEKYSNYFIKLVPSLKKNNFKGYFLIIIGSLYLGRESRGMSNISGMLLIGCGFFHIVYHYIHNMIYLKYDEGVIAYKRPVNLDNDDHYDELVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXC6</accession>
    <name>A0A1J1GXC6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">High mobility group protein B3, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">HMGB3</name>
        <name evidence="5" type="ORF">PGAL8A_00316200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528757.1">
        <property type="nucleotide sequence ID" value="XM_028672178.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731695"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00316200"/>
    <dbReference type="OMA" id="FGVDLMM"/>
    <dbReference type="OrthoDB" id="272624at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00084">
        <property type="entry name" value="HMG-box_SF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039467">
        <property type="entry name" value="TFIIIB_B''_Myb"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15963">
        <property type="entry name" value="Myb_DNA-bind_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="4">
        <location>
            <begin position="952"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="domain" description="HMG box" evidence="4">
        <location>
            <begin position="1022"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="1">
        <location>
            <begin position="952"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="1">
        <location>
            <begin position="1022"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="134"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="591"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="817"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1422"/>
            <end position="1484"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1595"/>
            <end position="1622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="593"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="621"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="643"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="683"/>
            <end position="697"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2685" mass="317203" checksum="4E8953F5F9944BCB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXJ5</accession>
    <name>A0A1J1GXJ5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Early transcribed membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00475900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529983.1">
        <property type="nucleotide sequence ID" value="XM_028673541.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXJ5"/>
    <dbReference type="GeneID" id="39733292"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00475900"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="194" mass="22651" checksum="1F261665933A8511" modified="2017-02-15" version="1">MRYLIIFFFYVLLIFILLGFNLSFASFISFQNLSSLKELDSKLENYKKKKKLLLSFTDIALAFSLGTLISGLLYLTLRFSNKKKKSLNKISTRNILKWLTNEGYKGNDTYENDTYENDTYEDETYENEINDNEINDNEENIRHSMLIGDSDTCEKKSHDESKPCYISCCEILKFRDISLGNIKIDPTESKTDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXM0</accession>
    <name>A0A1J1GXM0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00478300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530007.1">
        <property type="nucleotide sequence ID" value="XM_028673568.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733316"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00478300"/>
    <dbReference type="OMA" id="YVGKHER"/>
    <dbReference type="OrthoDB" id="377381at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="467"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1002"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1265"/>
            <end position="1395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="473"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1922" mass="229612" checksum="848CC0C261088805" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXM7</accession>
    <name>A0A1J1GXM7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Autophagy-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ATG8</name>
        <name evidence="7" type="ORF">PGAL8A_00479100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ATG8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530015.1">
        <property type="nucleotide sequence ID" value="XM_028673576.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXM7"/>
    <dbReference type="GeneID" id="39733324"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00479100"/>
    <dbReference type="OMA" id="EMFGCFL"/>
    <dbReference type="OrthoDB" id="6738456at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16108">
        <property type="entry name" value="Ubl_ATG8_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004241">
        <property type="entry name" value="Atg8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10969">
        <property type="entry name" value="MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02991">
        <property type="entry name" value="ATG8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0072">Autophagy</keyword>
    <keyword evidence="4 5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="lipid moiety-binding region" description="Phosphatidylserine amidated glycine; alternate" evidence="5">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604241-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="124" mass="14591" checksum="1F0704B6ACAD8F96" modified="2017-02-15" version="1">MPSLKEEVPFENRVAETHKIRAKYPNRIPVVCEKASRSDLPAIEKKKFLVPMNMLVGEFKFILHQHINQCAYGNNMKMFREKTIYIFVNNIVPKTGLLMQELYEMYKDEDGYLYLEYSCESCLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXN0</accession>
    <name>A0A1J1GXN0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00482600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530050.1">
        <property type="nucleotide sequence ID" value="XM_028673615.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXN0"/>
    <dbReference type="GeneID" id="39733359"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00482600"/>
    <dbReference type="OMA" id="STNFYQI"/>
    <dbReference type="OrthoDB" id="389992at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="79" mass="9535" checksum="187D85F4547CA8B6" modified="2017-02-15" version="1">MEGQRSLKKINVYKRLPYLYLGMFFIGGLLEVVFCSTNFYQIYNIGESEKKLENDMTYFMERYKLRQKIKEKATQISEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYB5</accession>
    <name>A0A1J1GYB5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATPTG10-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00483600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530059.1">
        <property type="nucleotide sequence ID" value="XM_028673625.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYB5"/>
    <dbReference type="GeneID" id="39733369"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00483600"/>
    <dbReference type="OMA" id="DTKMNMM"/>
    <dbReference type="OrthoDB" id="414429at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049262">
        <property type="entry name" value="ATPTG10-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20716">
        <property type="entry name" value="ATPTG10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPTG10-like" evidence="1">
        <location>
            <begin position="29"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="132" mass="15727" checksum="82C4349DFC49F480" modified="2017-02-15" version="1">MLINMVENKSCNHLKKLEEEKGNLKGNNLNLLLGDLKMMTAYEMSSEWKDTNMMNECFNNFSWFDSRILKNIQNYLNADEVERSKIDYAYNTLFPKPIDIKDTKLNMMSLWIKSRIHYNNTFFPLHLSPYDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYC2</accession>
    <name>A0A1J1GYC2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glutamine--fructose-6-phosphate aminotransferase [isomerizing]</fullName>
            <ecNumber evidence="2">2.6.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">GFPT</name>
        <name evidence="10" type="ORF">PGAL8A_00484400</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:13237"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="2.6.1.16"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.16" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530067.1">
        <property type="nucleotide sequence ID" value="XM_028673634.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYC2"/>
    <dbReference type="GeneID" id="39733377"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00484400"/>
    <dbReference type="OMA" id="ASEYRYA"/>
    <dbReference type="OrthoDB" id="15235at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004360">
        <property type="term" value="F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006047">
        <property type="term" value="P:UDP-N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00714">
        <property type="entry name" value="GFAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05008">
        <property type="entry name" value="SIS_GlmS_GlmD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05009">
        <property type="entry name" value="SIS_GlmS_GlmD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000006">
        <property type="entry name" value="Glutamine--fructose-6-phosphate aminotransferase [isomerizing]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10490:FF:000036">
        <property type="entry name" value="Glutamine-fructose-6-phosphate transaminase (Isomerizing), variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005855">
        <property type="entry name" value="GFAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047084">
        <property type="entry name" value="GFAT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035466">
        <property type="entry name" value="GlmS/AgaS_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035490">
        <property type="entry name" value="GlmS/FrlB_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01135">
        <property type="entry name" value="glmS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001484">
        <property type="entry name" value="PRK00331.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937">
        <property type="entry name" value="GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE, ISOMERIZING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937:SF0">
        <property type="entry name" value="GLUTAMINE--FRUCTOSE-6-PHOSPHATE TRANSAMINASE (ISOMERIZING)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13522">
        <property type="entry name" value="GATase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SIS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 10" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="8">
        <location>
            <begin position="143"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="9">
        <location>
            <begin position="432"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="9">
        <location>
            <begin position="606"/>
            <end position="747"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG97265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="757" mass="85173" checksum="CF0C2CACF194F695" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYG0</accession>
    <name>A0A1J1GYG0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00326200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000053">
        <property type="protein sequence ID" value="CRG96048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528856.1">
        <property type="nucleotide sequence ID" value="XM_028672289.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYG0"/>
    <dbReference type="GeneID" id="39731794"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00326200"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="138" mass="16904" checksum="C67DA8EE5C04BBCA" modified="2017-02-15" version="1">MKTFTLCLKIFTFLILTWIFHCFYNHNSSSSFINKDTFKINNRLKYQRLLAETDVLEKKQIHIKERKEYYPSGEKDNKDENLVNFKNIYIMLYSALFLSIYELFSKRTNYMSKECYLQSLVFYRKNISYERHLEELLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYR2</accession>
    <name>A0A1J1GYR2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00366500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529245.1">
        <property type="nucleotide sequence ID" value="XM_028672720.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732195"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00366500"/>
    <dbReference type="OMA" id="PTNMNNI"/>
    <dbReference type="OrthoDB" id="10266330at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.950">
        <property type="entry name" value="Methyl-accepting chemotaxis protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.500">
        <property type="entry name" value="TFIID subunit TAF5, NTD2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037264">
        <property type="entry name" value="TFIID_NTD2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879:SF7">
        <property type="entry name" value="PROTEASOMAL ATPASE-ASSOCIATED FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58104">
        <property type="entry name" value="Methyl-accepting chemotaxis protein (MCP) signaling domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160897">
        <property type="entry name" value="Taf5 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1011"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="1526"/>
            <end position="1553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1021"/>
            <end position="1041"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1888" mass="219604" checksum="62B8EA79D2F1A52F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYU6</accession>
    <name>A0A1J1GYU6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00521300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530438.1">
        <property type="nucleotide sequence ID" value="XM_028674046.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYU6"/>
    <dbReference type="GeneID" id="39733746"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00521300"/>
    <dbReference type="OrthoDB" id="372284at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="282" mass="33207" checksum="D7EA31673948DD50" modified="2017-02-15" version="1">MNYAAKKGKIHFNGFVKYSKKKKRPSNSIDYKRNIIKKENVNNIKEENVLCKMKKENIEINDQVEKRDESPITLYFNNKENYIRNDLPEGMLEKSSDTEYKDMDNYIIERIRNSSEFTNNNASLDDKNSDKSQTLSIKLKKEKKKNNLSCSKDPSRKKKCTLKKNDLDNKTLLINNSFSNPSYLPNYDNYGIQGPYYQTVYRRNKNKLKIEKYKKKYELPTIASLGKVKKLENLDLKINANLFNEKSKIILNNLSAYFGNKVNHDDIESSNNFKKKKKNYIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYZ1</accession>
    <name>A0A1J1GYZ1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Myosin light chain B, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">MLC-B</name>
        <name evidence="2" type="ORF">PGAL8A_00345300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529040.1">
        <property type="nucleotide sequence ID" value="XM_028672493.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYZ1"/>
    <dbReference type="GeneID" id="39731983"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00345300"/>
    <dbReference type="OMA" id="ITFFEIW"/>
    <dbReference type="OrthoDB" id="391857at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="303"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="387"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="630" mass="75332" checksum="C4B063D4C3FC3820" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ41</accession>
    <name>A0A1J1GZ41_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Actin-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ALP2b</name>
        <name evidence="4" type="ORF">PGAL8A_00026400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530629.1">
        <property type="nucleotide sequence ID" value="XM_028674258.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ41"/>
    <dbReference type="GeneID" id="39728787"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00026400"/>
    <dbReference type="OMA" id="NIACEIF"/>
    <dbReference type="OrthoDB" id="421448at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.36.70">
        <property type="entry name" value="Actin, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="148"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="605" mass="71107" checksum="A732D5112703D9BA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZA2</accession>
    <name>A0A1J1GZA2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">FAD-dependent monooxygenase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00520700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530432.1">
        <property type="nucleotide sequence ID" value="XM_028674039.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZA2"/>
    <dbReference type="GeneID" id="39733740"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00520700"/>
    <dbReference type="OrthoDB" id="1716816at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.9.10">
        <property type="entry name" value="D-Amino Acid Oxidase, subunit A, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050641">
        <property type="entry name" value="RIFMO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004:SF6">
        <property type="entry name" value="FAD_NAD(P)-BINDING OXIDOREDUCTASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43004">
        <property type="entry name" value="TRK SYSTEM POTASSIUM UPTAKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="4">
        <location>
            <begin position="6"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="4">
        <location>
            <begin position="268"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="701"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="707"/>
            <end position="717"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="962" mass="114400" checksum="8254F8F1C77FC31B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZH9</accession>
    <name>A0A1J1GZH9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Stripes inner membrane complex protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">SIP</name>
        <name evidence="2" type="ORF">PGAL8A_00031400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530678.1">
        <property type="nucleotide sequence ID" value="XM_028674313.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZH9"/>
    <dbReference type="GeneID" id="39728837"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00031400"/>
    <dbReference type="OMA" id="GFEAVWN"/>
    <dbReference type="OrthoDB" id="445338at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="244" mass="27961" checksum="9BD3D48796C0DE83" modified="2017-02-15" version="1">MSKTFSESHSQTENNSDKRSKIDDDVLSNADSNASSKKLNKKSVYSKKSNVQQLLARIAQEIDEREPSNVIHFIVDFLCKHYPEHLHGFESIWNGDPDLEQDRLLVVEFFKYQKLPVEISVHFINAGFDTVETLCTLSANSLDDVEKFSNTRWLPGHKVRLQQTFNDITNRVRRFKEERDSLIKSLRQGYISPSPIHSSSILPKSINPMMAPVISRVSSPINISTRTGNYVRVNEPVSSCFFKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZI8</accession>
    <name>A0A1J1GZI8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00045300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530819.1">
        <property type="nucleotide sequence ID" value="XM_028674470.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZI8"/>
    <dbReference type="GeneID" id="39728978"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00045300"/>
    <dbReference type="OMA" id="FNYIIPM"/>
    <dbReference type="OrthoDB" id="371771at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG98022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1236" mass="150715" checksum="56C2D0160BCC09B1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZL8</accession>
    <name>A0A1J1GZL8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tubulin--tyrosine ligase-like protein 9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">TTL</name>
        <name evidence="9" type="ORF">PGAL8A_00035500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the tubulin--tyrosine ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530718.1">
        <property type="nucleotide sequence ID" value="XM_028674357.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZL8"/>
    <dbReference type="GeneID" id="39728879"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00035500"/>
    <dbReference type="OMA" id="NDITMHL"/>
    <dbReference type="OrthoDB" id="202825at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070740">
        <property type="term" value="F:tubulin-glutamic acid ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004344">
        <property type="entry name" value="TTL/TTLL_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12241">
        <property type="entry name" value="TUBULIN POLYGLUTAMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12241:SF39">
        <property type="entry name" value="TUBULIN POLYGLUTAMYLASE TTLL9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03133">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51221">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="8">
        <location>
            <begin position="315"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="80"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG97919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="421" mass="50545" checksum="6F7E6E929E72B128" modified="2017-02-15" version="1">MSMYFRELFPSNKVIKFRTDFRNTIFDLFLHRKWELTNHETEWNLCWSEKDWINEVYDTISFKNNQYVNHFRNYYELTRKDLLAKNIKRLKKQNEKIKNEEEIKNLDITPMTFVLPLEYKIFLEEYKKKNNRIWIMKPIGKSQGKGIFLFDKISQIKEWNINKNKLNEEKDKEKEKPEQYIVQEYISNPLLIGGKKFDIRLYVLILSYYPLTIYLYRNGFARFSHTYFKNEKNNMNDITMHLTNISIQKNAEGYDDNVGGKWFIRELFLYLISRYGYKNIMTLIKDIENCIVQSFLAVHKIIINDKHCFELYGFDILIDNNLKPWLIEVNSSPSFSSNTKEDYTLKFNLLDELMTLINIEKYDIPTTDRVGDFDCIYRNGEKVNNVDPFNFYSYLGAHLSGTENLKNIAKNIKMKSNTIIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZS2</accession>
    <name>A0A1J1GZS2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">3'-phosphate/5'-hydroxy nucleic acid ligase</fullName>
            <ecNumber evidence="1">6.5.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00536100</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a 3'-end 3'-phospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP = a ribonucleotidyl-ribonucleotide-RNA + GMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:68076"/>
            <dbReference type="Rhea" id="RHEA-COMP:10463"/>
            <dbReference type="Rhea" id="RHEA-COMP:13936"/>
            <dbReference type="Rhea" id="RHEA-COMP:17355"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:83062"/>
            <dbReference type="ChEBI" id="CHEBI:138284"/>
            <dbReference type="ChEBI" id="CHEBI:173118"/>
            <dbReference type="EC" id="6.5.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="10">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.8" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530584.1">
        <property type="nucleotide sequence ID" value="XM_028674208.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZS2"/>
    <dbReference type="GeneID" id="39733894"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00536100"/>
    <dbReference type="OMA" id="AGRKWTR"/>
    <dbReference type="OrthoDB" id="10249697at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003909">
        <property type="term" value="F:DNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0170057">
        <property type="term" value="F:RNA ligase (GTP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042245">
        <property type="term" value="P:RNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1860.10">
        <property type="entry name" value="tRNA-splicing ligase RtcB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001233">
        <property type="entry name" value="RtcB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052915">
        <property type="entry name" value="RtcB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036025">
        <property type="entry name" value="RtcB-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43749">
        <property type="entry name" value="RNA-SPLICING LIGASE RTCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43749:SF2">
        <property type="entry name" value="RNA-SPLICING LIGASE RTCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01139">
        <property type="entry name" value="RtcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103365">
        <property type="entry name" value="Hypothetical protein PH1602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 10" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012859629" description="3'-phosphate/5'-hydroxy nucleic acid ligase" evidence="11">
        <location>
            <begin position="16"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="active site" description="GMP-histidine intermediate" evidence="8">
        <location>
            <position position="452"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="388"/>
            <end position="389"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="388"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="428"/>
            <end position="431"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="435"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="452"/>
            <end position="455"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="522"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG97783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="524" mass="60543" checksum="855E9C8BA1C6DD42" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZS3</accession>
    <name>A0A1J1GZS3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00377600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000130">
        <property type="protein sequence ID" value="CRG97975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530774.1">
        <property type="nucleotide sequence ID" value="XM_028674418.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZS3"/>
    <dbReference type="GeneID" id="39732306"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00377600"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="157" mass="19341" checksum="C4DFD2993B1E45B5" modified="2017-02-15" version="1">MLNLLLWVKKKRCKESLINEKILEEIETWKQWKNAKDEEFAKQEDYKSPENMYGCFAKLLWHIDQKRLKKIEDATQKDIKIIYYYKRHVSPIKGILKMMISTYNETPRSTITEFEEIFKSHYWITWKELEELEKKKSTLKKKKKLLKKMKNFKWKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0A8</accession>
    <name>A0A1J1H0A8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA-binding protein musashi, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">HoMu</name>
        <name evidence="5" type="ORF">PGAL8A_00429600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529520.1">
        <property type="nucleotide sequence ID" value="XM_028673026.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0A8"/>
    <dbReference type="GeneID" id="39732828"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00429600"/>
    <dbReference type="OrthoDB" id="1875751at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000567">
        <property type="entry name" value="RNA-binding protein musashi, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050886">
        <property type="entry name" value="RNA-binding_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48024">
        <property type="entry name" value="GEO13361P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48024:SF56">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="86"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="169"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="333" mass="38916" checksum="68C1222647DB8F2C" modified="2017-02-15" version="1">MTSEENINYNSNHSNSSSSQDKKSIEEQNSDDKSVKDDESEAEKLRRLIAPLSKEQLIDILATSAIIHQDIRDKCNEAVASSPSTRRLMVRNIPFSTRDEQFLKYFESFGEIEDGIIVREKEGRSKGYGFVTFKYVDSVQNCLKSSHTLDNKELQVRLVADPFTDHYQNKLFVRNLSQKTNVGTLRSIFEKYGKLEECVIIHDNEGKSKGYGFLTFSSPKEAFKVMQQPERIIDNRVVFLHFAVSQNYKKYQNNQNYVKKHQNYNYFQKNNINNRNNFVRRTPIYHHENEAPNTFNYPVSFVPNIYTNVPHGYQINYPSNLDSFNAFYNNPRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0D6</accession>
    <name>A0A1J1H0D6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">serine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Seryl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00064800</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.11" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028531006.1">
        <property type="nucleotide sequence ID" value="XM_028674678.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0D6"/>
    <dbReference type="GeneID" id="39729173"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00064800"/>
    <dbReference type="OMA" id="FEETLYC"/>
    <dbReference type="OrthoDB" id="10264585at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004828">
        <property type="term" value="F:serine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006434">
        <property type="term" value="P:seryl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00770">
        <property type="entry name" value="SerRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000085">
        <property type="entry name" value="Serine-tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.40">
        <property type="entry name" value="Serine-tRNA synthetase, tRNA binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002317">
        <property type="entry name" value="Ser-tRNA-ligase_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015866">
        <property type="entry name" value="Ser-tRNA-synth_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042103">
        <property type="entry name" value="SerRS_1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033729">
        <property type="entry name" value="SerRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00414">
        <property type="entry name" value="serS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11778">
        <property type="entry name" value="SERYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02403">
        <property type="entry name" value="Seryl_tRNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001529">
        <property type="entry name" value="Ser-tRNA-synth_IIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00981">
        <property type="entry name" value="TRNASYNTHSER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="tRNA-binding arm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="10">
        <location>
            <begin position="170"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="314"/>
            <end position="316"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="330"/>
            <end position="333"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="401"/>
            <end position="404"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="465"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for serine binding" evidence="8">
        <location>
            <position position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001529-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001529-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG98209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="508" mass="59045" checksum="B8877A39D7F961F0" modified="2017-02-15" version="1">MVIDINLFRREKGGNPEKIKESEKNRFHDETNVDKVIEYDEKWRKCIFKLEELKKSINIVNKEIGNKKKVDKNANVEDLIKKSLSMKEEIPLLQNEEKYLLKQRNTYLNKIGNILNKKVIVSNDELNNKVIKTWGVCKKLEVTNSINENTNEKREMGPINGSSSKLKYYHHFDLLKKIGGANFKKGIQVAGHRGYYLTGVGFLLHNAILQYALNFLVKKKYSPVYPPFFMKKNIMDECAELDDFEETLYKISSYNMDDNKNDLINKNVSNEESCRDDLYLIATSEQPLCALHRDEVLESKNLPLRYAGFSSCFRKEAGAHGKDIRGILRVHQFDKVEQFCISLPHTSNKIHQEMMKTCEEFYQSLNIPYRIISIVSGALNNAASIKYDLEGYFPCSDQYRELVSCSNCTDYQSINLNIKYTDSNIKITDLKKNEKVNINEEMDSDYENFIQNFHTESKNYVHLLNGTMVAAQRFLCCLLENYQNGEGIIVPEKLRPFMNNMEFIPFVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0F8</accession>
    <name>A0A1J1H0F8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Leucine-rich repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00459000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529813.1">
        <property type="nucleotide sequence ID" value="XM_028673352.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0F8"/>
    <dbReference type="GeneID" id="39733123"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00459000"/>
    <dbReference type="OMA" id="HAACERH"/>
    <dbReference type="OrthoDB" id="371675at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="305" mass="36257" checksum="BD8A243B9C78DAFB" modified="2017-02-15" version="1">MKNSLTENYIIITDKLKNDKFIEKKIKLKCRNLNINENIDDDIIDNFCNVLKKNKTFIGILDISYNNLNEINLFKVICSVYENKNITGLNIKYNKVTKMIFNKLLLIIENNNLEYLNIQNIELTNQEIKNIIFYTLNKNIKYLKLPYLNQEAFQYLIESLKKNDSLTKLHFFVGINNQNNSNNIHNENIINNYQNTIDNLKNLFKEFLDVIVNKINITNIECKINFQDEELEEMKSFIHSVCEKRKNLKTNKRFNEQELKINSLEIMKSLIPEITGKNKHIEKFEKEEHIIFEENVINVLQKLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0P1</accession>
    <name>A0A1J1H0P1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">STEEP1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00467900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the STEEP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529901.1">
        <property type="nucleotide sequence ID" value="XM_028673450.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0P1"/>
    <dbReference type="GeneID" id="39733212"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00467900"/>
    <dbReference type="OMA" id="FNEPTRM"/>
    <dbReference type="OrthoDB" id="418131at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090158">
        <property type="term" value="P:endoplasmic reticulum membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029704">
        <property type="entry name" value="STEEP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057965">
        <property type="entry name" value="STEEP1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46355:SF1">
        <property type="entry name" value="STING ER EXIT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46355">
        <property type="entry name" value="UPF0428 PROTEIN CXORF56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25809">
        <property type="entry name" value="STEEP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STEEP1" evidence="2">
        <location>
            <begin position="52"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00024205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="162" mass="19389" checksum="A7141983FE077970" modified="2017-02-15" version="1">MENENKEKNEISLLEIKRKVQTEHEASKDDNKQKKFRILNYTPKDSFVGKIEKDFLVYFCFLCGYNCLISEIDIYNLPTRKTDNSIIYPYKKIVHKKNHKVQTKRILINRKNGIEAQYRILCKECDVPIGYISNLNDDNSYIYYYNYSMLKDQTKCKIFIDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1H6</accession>
    <name>A0A1J1H1H6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00495800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530181.1">
        <property type="nucleotide sequence ID" value="XM_028673761.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1H6"/>
    <dbReference type="GeneID" id="39733491"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00495800"/>
    <dbReference type="OrthoDB" id="375561at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="703" mass="83477" checksum="F176281438C340C6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3E1</accession>
    <name>A0A1J1H3E1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine protein kinase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00044600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530812.1">
        <property type="nucleotide sequence ID" value="XM_028674462.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3E1"/>
    <dbReference type="GeneID" id="39728971"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00044600"/>
    <dbReference type="OMA" id="NTINFLY"/>
    <dbReference type="OrthoDB" id="426518at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044773">
        <property type="term" value="P:mitotic DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167">
        <property type="entry name" value="OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167:SF24">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE CHK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="731"/>
            <end position="1181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="488"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="654"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="654"/>
            <end position="670"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1182" mass="143560" checksum="F150BEFBBEAD4FBC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H414</accession>
    <name>A0A1J1H414_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00377900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000152">
        <property type="protein sequence ID" value="CRG98223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028531020.1">
        <property type="nucleotide sequence ID" value="XM_028674693.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732309"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00377900"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="373"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="460"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="592"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="708"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1434"/>
            <end position="1468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="380"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="460"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="592"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="620"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="648"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="708"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="721"/>
            <end position="735"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2048" mass="238076" checksum="20866A3C4D43E34E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H4E6</accession>
    <name>A0A1J1H4E6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00065700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000144">
        <property type="protein sequence ID" value="CRG98218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028531015.1">
        <property type="nucleotide sequence ID" value="XM_028674687.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H4E6"/>
    <dbReference type="GeneID" id="39729182"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00065700"/>
    <dbReference type="OMA" id="KHDRYES"/>
    <dbReference type="OrthoDB" id="372649at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="235" mass="27773" checksum="25D3668819421F9A" modified="2017-02-15" version="1">MTNNTLGSSLYHKNMINDKNEKILKKRKENNNKKLFLDESLSDISISTISNSTGIDSDLYNSVLKEIKEEKKRKKKLKKKSINENESTKNENLISMINLNEEQKAEKQKISQSSFDNKKRHKNKKDRRRKKKVRKSKSRSKCSYDDKIPKDPFNPLLLAYVKDNKVKYRKNDEDKLNFRWKHDRYESSSDEEDNEEREQNVNKALPKIDIFELRKNLWKSKAGGVCLSQISENLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2012-07-11" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>I2FKB8</accession>
    <name>I2FKB8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Phosphotransferase</fullName>
            <ecNumber evidence="11">2.7.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">HK</name>
        <name evidence="15" type="ORF">PGAL8A_00152500</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2012" name="Gene" volume="502" first="36" last="39">
            <title>Age of the last common ancestor of extant Plasmodium parasite lineages.</title>
            <authorList>
                <person name="Hayakawa T."/>
                <person name="Tachibana S."/>
                <person name="Hikosaka K."/>
                <person name="Arisue N."/>
                <person name="Matsui A."/>
                <person name="Horii T."/>
                <person name="Tanabe K."/>
            </authorList>
            <dbReference type="PubMed" id="22555021"/>
            <dbReference type="DOI" id="10.1016/j.gene.2012.04.037"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="15 16" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-fructose + ATP = D-fructose 6-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37721"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:16126"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a D-hexose + ATP = a D-hexose 6-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22740"/>
            <dbReference type="ChEBI" id="CHEBI:4194"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:229467"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:22741"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; hexose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the hexokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.-" evidence="11"/>
    <dbReference type="EMBL" id="AB571127">
        <property type="protein sequence ID" value="BAM15603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="I2FKB8"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00152500"/>
    <dbReference type="OMA" id="ADCVQQF"/>
    <dbReference type="OrthoDB" id="419537at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005536">
        <property type="term" value="F:D-glucose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008865">
        <property type="term" value="F:fructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004340">
        <property type="term" value="F:glucokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001678">
        <property type="term" value="P:intracellular glucose homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd24000">
        <property type="entry name" value="ASKHA_NBD_HK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.367.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001312">
        <property type="entry name" value="Hexokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019807">
        <property type="entry name" value="Hexokinase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022673">
        <property type="entry name" value="Hexokinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022672">
        <property type="entry name" value="Hexokinase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443">
        <property type="entry name" value="HEXOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19443:SF16">
        <property type="entry name" value="HEXOKINASE TYPE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00349">
        <property type="entry name" value="Hexokinase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03727">
        <property type="entry name" value="Hexokinase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00475">
        <property type="entry name" value="HEXOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00378">
        <property type="entry name" value="HEXOKINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51748">
        <property type="entry name" value="HEXOKINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 11" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6 11 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Hexokinase N-terminal" evidence="12">
        <location>
            <begin position="33"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Hexokinase C-terminal" evidence="13">
        <location>
            <begin position="262"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="BAM15603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG93816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="489" mass="54801" checksum="45A8A49006AB4CB6" modified="2012-07-11" version="1">MGEYNLVQDNVVYSKLDTIECDIPINEELLERINKFVDHLRLPYYLLEEFVDNFVYELKKGLEAHRKHPNLWIPHECSFKMLDSCISEIPSGKEKGTYYAIDFGGTNFRAVRASLDGNGKIKRDQETYSLKFTGTFSHEKGLLDKNATASQLFDHFAERIKYIMGEFNDLDSKEVKSVGFTFSFPCTSPSINCAILIDWTKGFETGRATNDPVEGRDVCKLMNEAFTRSSVPAKVCCVVNDAVGTLMSCAYQKGKSTPPCYIGIILGTGSNGCYYEPEWKKYKYSGKIINIEFGNFDKDLPLAPIDLVMDWYSSNRSRQLFEKMISGAYLGEMVRRYMVNVLQSASSKKMWITDTFNSESGSVVLNDTSKNFEETRKVAKDAWDIDLTDEQVYALRKICEAVYNRSAGLAAGAIAAIAKRIKIIEHSKFSCGVDGSLFVKNAWYCKRLQEHLKVILADKSENLIIIPADDGSGKGAAITAAVVASCSNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL75</accession>
    <name>A0A1J1GL75_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nucleolar protein 10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00077700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525897.1">
        <property type="nucleotide sequence ID" value="XM_028670211.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL75"/>
    <dbReference type="GeneID" id="39729302"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00077700"/>
    <dbReference type="OMA" id="GYFMDVR"/>
    <dbReference type="OrthoDB" id="273340at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056551">
        <property type="entry name" value="Beta-prop_NOL10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040382">
        <property type="entry name" value="NOL10/Enp2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056550">
        <property type="entry name" value="NOL10_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14927">
        <property type="entry name" value="NUCLEOLAR PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14927:SF0">
        <property type="entry name" value="NUCLEOLAR PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23098">
        <property type="entry name" value="Beta-prop_NOL10_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23097">
        <property type="entry name" value="NOL10_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleolar protein 10-like N-terminal" evidence="2">
        <location>
            <begin position="6"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleolar protein 10-like second" evidence="1">
        <location>
            <begin position="407"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="538" mass="63343" checksum="55922CB307A31401" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLC9</accession>
    <name>A0A1J1GLC9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00084400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525962.1">
        <property type="nucleotide sequence ID" value="XM_028670932.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLC9"/>
    <dbReference type="GeneID" id="39729368"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00084400"/>
    <dbReference type="OrthoDB" id="1918at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="436"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="525"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="439"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="530"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="912" mass="109606" checksum="0BFB112A3D748152" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLM4</accession>
    <name>A0A1J1GLM4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00103400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526150.1">
        <property type="nucleotide sequence ID" value="XM_028673021.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLM4"/>
    <dbReference type="GeneID" id="39729559"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00103400"/>
    <dbReference type="OrthoDB" id="374963at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="551"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="462"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="469"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="574" mass="67659" checksum="57E384BAC3D625FA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM52</accession>
    <name>A0A1J1GM52_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Lipase maturation factor 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">LMF1</name>
        <name evidence="12" type="ORF">PGAL8A_00117900</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the lipase maturation factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526295.1">
        <property type="nucleotide sequence ID" value="XM_028674632.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM52"/>
    <dbReference type="GeneID" id="39729704"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00117900"/>
    <dbReference type="OMA" id="CYIICNY"/>
    <dbReference type="OrthoDB" id="434126at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009613">
        <property type="entry name" value="LMF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057433">
        <property type="entry name" value="LMF1/2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057434">
        <property type="entry name" value="LMF1/2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14463">
        <property type="entry name" value="LIPASE MATURATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14463:SF5">
        <property type="entry name" value="LIPASE MATURATION FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06762">
        <property type="entry name" value="LMF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25179">
        <property type="entry name" value="LMF1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="63"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="136"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="278"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="302"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="354"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="407"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="Lipase maturation factor 1/2 N-terminal" evidence="10">
        <location>
            <begin position="188"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="Lipase maturation factor 1/2 C-terminal" evidence="11">
        <location>
            <begin position="417"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00040643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF06762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF25179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG93473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="588" mass="71771" checksum="89E9DF067E6218D8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM65</accession>
    <name>A0A1J1GM65_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF155 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00112500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RMD1/sif2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526241.1">
        <property type="nucleotide sequence ID" value="XM_028674032.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM65"/>
    <dbReference type="GeneID" id="39729650"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00112500"/>
    <dbReference type="OMA" id="IDIVWTI"/>
    <dbReference type="OrthoDB" id="18302at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003734">
        <property type="entry name" value="DUF155"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051624">
        <property type="entry name" value="RMD1/Sad1-interacting"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16255">
        <property type="entry name" value="REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16255:SF1">
        <property type="entry name" value="REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02582">
        <property type="entry name" value="DUF155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="358"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="DUF155" evidence="3">
        <location>
            <begin position="148"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="385" mass="45863" checksum="824617B4B39B1977" modified="2017-02-15" version="1">MYVLFKDQLKDEDEKNDKLHIRYNGQNNSSSENENTLSSKYFRKENRRFKHNLNILDKTKPLSILGNTLQKKLELPIDKQNELDILKKKKNIEPTGIVIACCLGTDFHFSAFIKDFKTYNINSDFIKIKKVYSEVIFCSAFEQKKIFFLFRFGCIVLWDFNIKEKEILFMNLKDYLSEAYTENNNELDSMFYIMSIPNDLSDSKNKDMPECSFKIKNDIIYIYTKDIFEKLSYSYAFAQSVKLSYFENVVDDTIDKTKGIPECLARTGKIQLKKNDISKKIGELFVNRFYINMNTDMLDTPEIFWDHDDFTDTYEYFRKYLDISKRVEILNHRLDIIKDLYDMLQNELTIQHGYKLEWIVIYLICIEVIIDIVWTIIIKGVFKWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM81</accession>
    <name>A0A1J1GM81_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Alpha/beta-hydrolase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00116600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526282.1">
        <property type="nucleotide sequence ID" value="XM_028674488.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM81"/>
    <dbReference type="GeneID" id="39729691"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00116600"/>
    <dbReference type="OMA" id="LHFYDKN"/>
    <dbReference type="OrthoDB" id="10249433at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052920">
        <property type="entry name" value="DNA-binding_regulatory"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43358">
        <property type="entry name" value="ALPHA/BETA-HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43358:SF4">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="499" mass="58820" checksum="F9DADCD783B2DBFD" modified="2017-02-15" version="1">MFHLYELLMFFLRHPRDEYDEEFLGPNFLHFYDKNYYRKDIIIKNRRGEKLKCCHFTPFNYNENTPCVIYTHSTSSCQLETLDILHILLICDCSIFSYDCAGCGLSDGFYSTKGWNESQDLYLILNHLRNIEKIKNFVLWGKYSGAVSSIITAALDGNIKLLILDSPYVSLTELYKTTFHLNAKGKREIIFKNICLYFARKEIKKKFHYDINNVCPIFFIENITTPTIYIISKNDKIVHPAHSLYLAYKQKRANKTIYISEKTVQSYESFSYENKLTVAIKSILYDSSFESDTRTVFDESAYSKLFNGLKDKYSYEFNFIDKLITKKQKQKKKIIDNVKRFICFKYKTQSSLNSSNCLYQSTLCSMRDINPNENEFMRYESADNIKYENYKNEKSIGTKIINEYEDLFPDVENIINESNEINLLKSSDNGNLIKLNQTYKEIDGEKNQKHFKILHMQSARSSLKSNKNTYKKSLTWDSKLHSSITYFKEDCPFELMKNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM99</accession>
    <name>A0A1J1GM99_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00122800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526343.1">
        <property type="nucleotide sequence ID" value="XM_028674742.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729753"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00122800"/>
    <dbReference type="OMA" id="KNEIMMI"/>
    <dbReference type="OrthoDB" id="378915at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1313"/>
            <end position="1332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1554"/>
            <end position="1582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2113"/>
            <end position="2133"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3099"/>
            <end position="3136"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3225"/>
            <end position="3252"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3333"/>
            <end position="3463"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3524"/>
            <end position="3596"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3714"/>
            <end position="3761"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3849"/>
            <end position="3939"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="4067"/>
            <end position="4166"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="4227"/>
            <end position="4382"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="4424"/>
            <end position="4451"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="4482"/>
            <end position="4535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1572"/>
            <end position="1582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="4667" mass="559731" checksum="D49C65DD34F7CD83" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMQ2</accession>
    <name>A0A1J1GMQ2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Thiamin-phosphate pyrophosphorylase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00142600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; thiamine diphosphate biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526542.1">
        <property type="nucleotide sequence ID" value="XM_028674963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMQ2"/>
    <dbReference type="GeneID" id="39729950"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00142600"/>
    <dbReference type="OMA" id="YIAHEHT"/>
    <dbReference type="OrthoDB" id="4994at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004789">
        <property type="term" value="F:thiamine-phosphate diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00564">
        <property type="entry name" value="TMP_TenI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036206">
        <property type="entry name" value="ThiamineP_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022998">
        <property type="entry name" value="ThiamineP_synth_TenI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20857:SF23">
        <property type="entry name" value="THIAMINE BIOSYNTHETIC BIFUNCTIONAL ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20857">
        <property type="entry name" value="THIAMINE-PHOSPHATE PYROPHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02581">
        <property type="entry name" value="TMP-TENI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51391">
        <property type="entry name" value="Thiamin phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0784">Thiamine biosynthesis</keyword>
    <feature type="domain" description="Thiamine phosphate synthase/TenI" evidence="3">
        <location>
            <begin position="19"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="509" mass="59048" checksum="39A2B5321FB5789E" modified="2017-02-15" version="1">MMKSYNFIKSIKRSINYSLYLVTDDKFLKDKENVCQHFIDKIVEGVLGGVSLVQLRLKKSDDIYFYNMAVKVKNKLNQHNIPLIINNRLDICLSVDADGVHLGKTDIPLNIARNVLGEKKIIGATINFSDEKDIEMAINNNIDYIAHEHSLYDSETKKTTSSYAVGLIEQINLLQCKIKCLKEKRKISPYSKIPPILLIGGINTMNIKETMINFYDICSGIAIASGIIGEYSNPFLNALKLRFIIDKYKNNYNIAFINMYSNLLNYLFYKITNNEVCIKNILKEKNEQENKNFMNEVVTNANIKKNVLNFFINNCKHKILQLNQSIINNSKIKVYLYESKFLYSNNQSSSIVNNSHYDECVIKWIEKNKNESIKNKIFILIGEEILHLFKKYFQPEFFKLNFFFLIEKNSQISYDSFKHFEYDIENVSIKYAENFINIILKNNFFNDDKVLILGLFLSYFLITQEKIAPQFLSKIITESNSIDDDTLLKCIGAIDISLKLLGNKQIIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMQ5</accession>
    <name>A0A1J1GMQ5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PGAL8A_00135700</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526474.1">
        <property type="nucleotide sequence ID" value="XM_028674887.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMQ5"/>
    <dbReference type="GeneID" id="39729882"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00135700"/>
    <dbReference type="OMA" id="ICSICMM"/>
    <dbReference type="OrthoDB" id="21204at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45977:SF4">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45977">
        <property type="entry name" value="TARGET OF ERK KINASE MPK-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="31"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="142"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="14">
        <location>
            <begin position="304"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG93652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="361" mass="42704" checksum="0CD0F08227087CD9" modified="2017-02-15" version="1">MNIDSEDINNNDGNFTHINNTEMIIFRYFTIFLYFLLFCNIFSLFGLGIYFLSIPCEKCDFYNRILVTVILVKSIAHLKLTIIKVKRRDEIENNERLKNIIVFLIKIFNFLTFLLAVVSLYFLHFYNNICVTPTLSLKLIRIYYYFTITLYFIPLLFYISIGLFLSIIICIMINYSVEEGDRIPTPENIISRLKIVKYKDLDYIHKKGKKSNKNKKYIKKPSFEMIFDKVKSVIIDKENNEKKKKMQLNSSNSNIIDENLQEMLKPLNTNIESEINYNNDNNKVTQENLLNNNKEISNENEDVCSICMMNYINNDDVMIMPCDKRHFFHVSCLTKWLYKSQVCPICRTNIVNCFNSKNNIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMV6</accession>
    <name>A0A1J1GMV6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00000900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000018">
        <property type="protein sequence ID" value="CRG93597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526419.1">
        <property type="nucleotide sequence ID" value="XM_028674827.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMV6"/>
    <dbReference type="GeneID" id="39728531"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00000900"/>
    <dbReference type="OMA" id="YSCIHEN"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="195" mass="22524" checksum="A3504A4ED13BDAF4" modified="2017-02-15" version="1">MAYRNLQNVKLTNASSAKYGSPEKCTYSCIHENKEKSNNEESFKQWLHKFNTRKLTQRNEEKNNKCQSNEITDKGIPKENSSTDENPSKNNDYECLVACSPCFSIYAKIDCIKECLIRENDNEASIDQKRDSQSNDDQENASQSNDDQENASQSNDDQENDSQSNDNEENSPKLSLRERFSKKPYEVIYFVTLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN50</accession>
    <name>A0A1J1GN50_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="10">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">HAS1</name>
        <name evidence="15" type="ORF">PGAL8A_00159500</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="10">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="10"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526708.1">
        <property type="nucleotide sequence ID" value="XM_028675148.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN50"/>
    <dbReference type="GeneID" id="39730120"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00159500"/>
    <dbReference type="OMA" id="LMEFHSQ"/>
    <dbReference type="OrthoDB" id="10259640at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17942">
        <property type="entry name" value="DEADc_DDX18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000379">
        <property type="entry name" value="RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002173">
        <property type="entry name" value="RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044773">
        <property type="entry name" value="DDX18/Has1_DEADc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025313">
        <property type="entry name" value="SPB4-like_CTE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13959">
        <property type="entry name" value="CTE_SPB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01178">
        <property type="entry name" value="DUF4217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9 15" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 9 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="14">
        <location>
            <begin position="160"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="191"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="377"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="8">
        <location>
            <begin position="160"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="8"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG93887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="613" mass="71069" checksum="C4F11279E93D8BC6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN82</accession>
    <name>A0A1J1GN82_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">glutamate--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Glutamyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00163600</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.17" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526748.1">
        <property type="nucleotide sequence ID" value="XM_028675192.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN82"/>
    <dbReference type="GeneID" id="39730161"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00163600"/>
    <dbReference type="OMA" id="WMNKKYL"/>
    <dbReference type="OrthoDB" id="428822at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004818">
        <property type="term" value="F:glutamate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006424">
        <property type="term" value="P:glutamyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00808">
        <property type="entry name" value="GluRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00022">
        <property type="entry name" value="Glu_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008925">
        <property type="entry name" value="aa_tRNA-synth_I_cd-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004527">
        <property type="entry name" value="Glu-tRNA-ligase_bac/mito"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049940">
        <property type="entry name" value="GluQ/Sye"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033910">
        <property type="entry name" value="GluRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00464">
        <property type="entry name" value="gltX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43311">
        <property type="entry name" value="GLUTAMATE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43311:SF2">
        <property type="entry name" value="GLUTAMATE--TRNA LIGASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48163">
        <property type="entry name" value="An anticodon-binding domain of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011977968" description="glutamate--tRNA ligase" evidence="10">
        <location>
            <begin position="18"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic" evidence="11">
        <location>
            <begin position="82"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG93927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="569" mass="68123" checksum="4D6573BB9DF0E253" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNB2</accession>
    <name>A0A1J1GNB2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Histone H3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">H3.3</name>
        <name evidence="11" type="ORF">PGAL8A_00146300</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the histone H3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526579.1">
        <property type="nucleotide sequence ID" value="XM_028675005.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNB2"/>
    <dbReference type="SMR" id="A0A1J1GNB2"/>
    <dbReference type="GeneID" id="39729987"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00146300"/>
    <dbReference type="OMA" id="ANDCAIH"/>
    <dbReference type="OrthoDB" id="4025405at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22911">
        <property type="entry name" value="HFD_H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000078">
        <property type="entry name" value="Histone H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000044">
        <property type="entry name" value="Histone H3.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000164">
        <property type="entry name" value="Histone_H3/CENP-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11426">
        <property type="entry name" value="HISTONE H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00622">
        <property type="entry name" value="HISTONEH3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00428">
        <property type="entry name" value="H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00322">
        <property type="entry name" value="HISTONE_H3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00959">
        <property type="entry name" value="HISTONE_H3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 8" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="10">
        <location>
            <begin position="44"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG93757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="136" mass="15441" checksum="958FFE8DDF9543F0" modified="2017-02-15" version="1">MARTKQTARKSTGGKAPRKQLASKAARKSAPVSTGIKKPHRYRPGTVALREIRKFQKSTDLLIRKLPFQRLVREIAQEYKTDLRFQSQAVLALQEAAEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNC6</accession>
    <name>A0A1J1GNC6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">SNF1-related protein kinase catalytic subunit alpha, putative</fullName>
            <ecNumber evidence="9">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SNF1</name>
        <name evidence="9" type="ORF">PGAL8A_00159300</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="9"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526706.1">
        <property type="nucleotide sequence ID" value="XM_028675146.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNC6"/>
    <dbReference type="GeneID" id="39730118"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00159300"/>
    <dbReference type="OMA" id="VCGVEYL"/>
    <dbReference type="OrthoDB" id="431723at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF82">
        <property type="entry name" value="KP78A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="10"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="668" mass="80395" checksum="B29C88341EB04F36" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNT5</accession>
    <name>A0A1J1GNT5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Zinc finger C-x8-C-x5-C-x3-H type, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00384700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526964.1">
        <property type="nucleotide sequence ID" value="XM_028670186.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNT5"/>
    <dbReference type="GeneID" id="39732377"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00384700"/>
    <dbReference type="OMA" id="NQSKCRF"/>
    <dbReference type="OrthoDB" id="415459at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045877">
        <property type="entry name" value="ZFP36-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12547">
        <property type="entry name" value="CCCH ZINC FINGER/TIS11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12547:SF18">
        <property type="entry name" value="PROTEIN TIS11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="11"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="83"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="11"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="83"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG94143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="270" mass="31691" checksum="6EC6605D989F2DF1" modified="2017-02-15" version="1">MSVSSEIKYQFARTKICKHFLENKCLNKDNCNYAHVLEELRPLPNLINTKLCKSLKKNEVCNIPNCKYAHKIEHLQPSTNLSTYKTTMCYFWKKKKCMNESKCRFAHGIKEIRPLNIKKKTVKEKNLLESKENVDLDTDECIRNLLSNVLFFENLSTIKKDLLSSGNDFLNNYKNFNLDNSAFSISRGNNYSNSNYTEKSEHHSLDTFFLERNIPNLNYIPSKKENENLELLSFNDVSTTAELNDDDYFNELYKCIKKELSKNYENICSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP80</accession>
    <name>A0A1J1GP80_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Gamma tubulin complex component protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00400100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527118.1">
        <property type="nucleotide sequence ID" value="XM_028670358.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732531"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00400100"/>
    <dbReference type="OMA" id="YYLDFIC"/>
    <dbReference type="OrthoDB" id="775571at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="797"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1071"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1494"/>
            <end position="1525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1494"/>
            <end position="1523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1976" mass="241102" checksum="F062D7F0EF438419" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPJ8</accession>
    <name>A0A1J1GPJ8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine protein kinase, putative</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00405300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527170.1">
        <property type="nucleotide sequence ID" value="XM_028670415.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732583"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00405300"/>
    <dbReference type="OMA" id="CNTPNKC"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044773">
        <property type="term" value="P:mitotic DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167">
        <property type="entry name" value="OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167:SF24">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE CHK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="1177"/>
            <end position="1631"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1065"/>
            <end position="1110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1635" mass="194863" checksum="973C3DFFF920C71A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPQ3</accession>
    <name>A0A1J1GPQ3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">cysteine desulfurase</fullName>
            <ecNumber evidence="3">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00097700</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526093.1">
        <property type="nucleotide sequence ID" value="XM_028672388.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPQ3"/>
    <dbReference type="GeneID" id="39729501"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00097700"/>
    <dbReference type="OMA" id="AMDIPYT"/>
    <dbReference type="OrthoDB" id="10250117at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000003">
        <property type="entry name" value="Cysteine desulfurase IscS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010611">
        <property type="entry name" value="PRK14012.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11601:SF34">
        <property type="entry name" value="CYSTEINE DESULFURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11601">
        <property type="entry name" value="CYSTEINE DESULFURYLASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="10">
        <location>
            <begin position="121"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG93271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="524" mass="60081" checksum="C7C077E5B89AA7E1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPT5</accession>
    <name>A0A1J1GPT5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Suppressor of forked domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00073800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525856.1">
        <property type="nucleotide sequence ID" value="XM_028675001.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPT5"/>
    <dbReference type="GeneID" id="39729263"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00073800"/>
    <dbReference type="OrthoDB" id="26282at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045243">
        <property type="entry name" value="Rna14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008847">
        <property type="entry name" value="Suf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19980:SF0">
        <property type="entry name" value="CLEAVAGE STIMULATION FACTOR SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19980">
        <property type="entry name" value="RNA CLEAVAGE STIMULATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23240">
        <property type="entry name" value="HAT_PRP39_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05843">
        <property type="entry name" value="Suf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Suppressor of forked" evidence="5">
        <location>
            <begin position="287"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="509"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="591"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="513"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1181" mass="142621" checksum="7560E2DF56E6DF3E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPV3</accession>
    <name>A0A1J1GPV3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00193100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000029">
        <property type="protein sequence ID" value="CRG94533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527348.1">
        <property type="nucleotide sequence ID" value="XM_028670613.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPV3"/>
    <dbReference type="GeneID" id="39730456"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00193100"/>
    <dbReference type="OMA" id="SWDIPNT"/>
    <dbReference type="OrthoDB" id="406773at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="248" mass="29176" checksum="B6E3444A4278EC6D" modified="2017-02-15" version="1">MNYLKKYEHKVLSDTLRFLGFTFKWGIHENGYWLTNLNYSFNYILSNLIIKYLKEKNVKSVVDIGCGYGDYVNELNFHKIKSVGIDGNFKLLNSLKNENLYILDATSEYFISDLMNKINNSIKKENVKKDKLLEKNEIIKKGGNGIRSFFKFDYALCLNVGEYIPKKKEEIFIKNIDRINSKGVILSWDTPNNFNIGTINEKKEDEILEIFSNNYSYIYDEKNSKIFRDNCSNDSPKKCIYIFEKKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPY1</accession>
    <name>A0A1J1GPY1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-f protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00187500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000025">
        <property type="protein sequence ID" value="CRG94480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527298.1">
        <property type="nucleotide sequence ID" value="XM_028670558.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPY1"/>
    <dbReference type="GeneID" id="39730402"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00187500"/>
    <dbReference type="OMA" id="LRIMNTK"/>
    <dbReference type="OrthoDB" id="1490254at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="591" mass="70834" checksum="A50A244F18CCD462" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ29</accession>
    <name>A0A1J1GQ29_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00410500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527219.1">
        <property type="nucleotide sequence ID" value="XM_028670470.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ29"/>
    <dbReference type="GeneID" id="39732635"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00410500"/>
    <dbReference type="OrthoDB" id="10604164at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="258" mass="29479" checksum="5A04D27854BF765B" modified="2017-02-15" version="1">MAEHNNFVLNNSTNIEGLTQHVNNSHELTPNASESLSEITNTNDLQIFNQTNSCHKQINSSPQMHQSMTELRESSTNIINITNEVTESKSHICNVSTQLCNLTKQICNNTENLCNNTENLCNNTGQLSMTHLCNSTTNLCNTALQLCNGTSSNTTVHRFVPSLSSFERLTIDFFSIWLMYGFLLIAVIYKHFFQNIVKKLFCRRTSHYEPISRGENEQDEARVTEEEIQEISDETVIEMVDIRNVDEENKSLFKRNCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ76</accession>
    <name>A0A1J1GQ76_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Centrosomal protein of 70 kDa</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00199200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Directly interacts with tubulin-gamma; this interaction determines centrosomal localization.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527410.1">
        <property type="nucleotide sequence ID" value="XM_028670682.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730519"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00199200"/>
    <dbReference type="OMA" id="AGKMNMS"/>
    <dbReference type="OrthoDB" id="378253at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005813">
        <property type="term" value="C:centrosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043015">
        <property type="term" value="F:gamma-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070507">
        <property type="term" value="P:regulation of microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037692">
        <property type="entry name" value="CEP70"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14594">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 70 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14594:SF1">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 70 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0802">TPR repeat</keyword>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="425"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1223"/>
            <end position="1338"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1370"/>
            <end position="1440"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1481"/>
            <end position="1515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG94595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1989" mass="235645" checksum="E35B8CC751CFB112" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQC3</accession>
    <name>A0A1J1GQC3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Replication factor A protein 3, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00201300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the replication factor A protein 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527431.1">
        <property type="nucleotide sequence ID" value="XM_028670705.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQC3"/>
    <dbReference type="GeneID" id="39730539"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00201300"/>
    <dbReference type="OMA" id="IAPRVNK"/>
    <dbReference type="OrthoDB" id="188186at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005662">
        <property type="term" value="C:DNA replication factor A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013970">
        <property type="entry name" value="Rfa2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15114:SF1">
        <property type="entry name" value="REPLICATION PROTEIN A 14 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15114">
        <property type="entry name" value="REPLICATION PROTEIN A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08661">
        <property type="entry name" value="Rep_fac-A_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="109" mass="12765" checksum="2FCC61D316B1A864" modified="2017-02-15" version="1">MEQYIAPRVNKKYLKNFFNKNVRIVGKILKKDGNELILQTPDNGEIKCFLNENQMVDSLDKYIEVLGRVNEDETLSDIVYIQNGGNNINMNELNNLINMTFLEEFEEIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQE0</accession>
    <name>A0A1J1GQE0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Pyruvate dehydrogenase E1 component subunit beta, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00205600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>N(6)-[(R)-lipoyl]-L-lysyl-[protein] + pyruvate + H(+) = N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:19189"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10478"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="1.2.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527474.1">
        <property type="nucleotide sequence ID" value="XM_028670752.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQE0"/>
    <dbReference type="GeneID" id="39730583"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00205600"/>
    <dbReference type="OMA" id="VRLCTKD"/>
    <dbReference type="OrthoDB" id="10266385at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004739">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07036">
        <property type="entry name" value="TPP_PYR_E1-PDHc-beta_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000001">
        <property type="entry name" value="Pyruvate dehydrogenase E1 beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006667">
        <property type="entry name" value="PRK09212.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43257">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE E1 COMPONENT BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43257:SF2">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009618919" evidence="6">
        <location>
            <begin position="25"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="7">
        <location>
            <begin position="83"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00051231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="404" mass="45442" checksum="1BD4957147B18A4A" modified="2017-02-15" version="1">MERGIKRYIVFFFFLVSSILKCKSKKKSGSLNFISLKNLSNGMKIKNKHLKETNRIHIVAEENSVILNDQNYMNEIKNVKVKRNVSEALHMAVYEEMKKDKNVYVLGEDVGLYGGSYKVTKNLAHFFGFARVLDTPICENAFMGLGIGSAINGLRPIIEGMNLSFLILAFNQISNNACMMRYMCDGQFNIPIVIRGPGGVGKQLGPEHSQRIESYLMSIPGIKIVSCSTPYNARGLLKSAIRDNNPVLFLEHVLLYNLEEEIPLLPYTLPIDKAEVVKSGTDLTILCYGITRHIAMEAAKELNKINIDVEIIDLISLKPFDMETIGYSLKKTQKCLILDESAGFGGIGAELYTQIVEKFSPYLKRVPSRLCTKDIPIAYSDKYEDACIIKKEDVVYMSTYLHSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQF7</accession>
    <name>A0A1J1GQF7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Heat shock protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00123400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526349.1">
        <property type="nucleotide sequence ID" value="XM_028674749.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQF7"/>
    <dbReference type="GeneID" id="39729759"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00123400"/>
    <dbReference type="OMA" id="QEETHEY"/>
    <dbReference type="OrthoDB" id="28737at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16927">
        <property type="entry name" value="HATPase_Hsp90-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000005">
        <property type="entry name" value="Heat shock protein 90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019805">
        <property type="entry name" value="Heat_shock_protein_90_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001404">
        <property type="entry name" value="Hsp90_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020575">
        <property type="entry name" value="Hsp90_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11528">
        <property type="entry name" value="HEAT SHOCK PROTEIN 90 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00775">
        <property type="entry name" value="HEATSHOCK90"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00298">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0346">Stress response</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012656049" evidence="6">
        <location>
            <begin position="28"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase/HSP90-like ATPase" evidence="7">
        <location>
            <begin position="118"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="33"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="41"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="303" mass="34616" checksum="B03C881A44E16BED" modified="2017-02-15" version="1">MRLNKLYTYMFLLFLLNLILENTKIFCENNNTDDNAKEESNSEEEKDTAEEFGDVSSGEHPKQDDGETNVNKKERKKVQDNIPEIEESEKPLDSIENHEYQTEVTRLMDIIVNSLYTHKEVFLRELISNAADALEKIRFLSLSDESVLGEEKKLEIRISTNPEKNILSITDTGIGMTKDDLINNLGTIAKSGTSNFLEAISKSGGDMSLIGQFGVGFYSAFLVADKVIVYTKNNNDDQYIWESTADAKFSIYKDPRGSTLKRGTRISLHLKEDATNLLNDKKIIDLISKYSQFIQFPFFFFFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQH0</accession>
    <name>A0A1J1GQH0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">OPA3-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00218600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the OPA3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527604.1">
        <property type="nucleotide sequence ID" value="XM_028670897.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQH0"/>
    <dbReference type="GeneID" id="39730713"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00218600"/>
    <dbReference type="OMA" id="KMYVMNL"/>
    <dbReference type="OrthoDB" id="2129069at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019216">
        <property type="term" value="P:regulation of lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010754">
        <property type="entry name" value="OPA3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12499:SF0">
        <property type="entry name" value="OPTIC ATROPHY 3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12499">
        <property type="entry name" value="OPTIC ATROPHY 3 PROTEIN OPA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07047">
        <property type="entry name" value="OPA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="110"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="193" mass="22889" checksum="D204CA4B22F72811" modified="2017-02-15" version="1">MIPFFKIGIVLIRQVSKPISRYIKNKAIENKKFKSICIYCGKKYYFFEQYIQKKFYNSNTTNVNYSSFISENKSVNVGSEILGETIIFFIAALIIVAEYKRNSLKEAKKELILNHKLDTLRLQVKELQRENDEIMKIVLPHKKNIRDKRSFDLVHTNFFKDIYNKVMNKSKEITNNEENNNKDNIKKLNDSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQK9</accession>
    <name>A0A1J1GQK9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PIR-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00194500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000030">
        <property type="protein sequence ID" value="CRG94548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527363.1">
        <property type="nucleotide sequence ID" value="XM_028670629.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQK9"/>
    <dbReference type="GeneID" id="39730471"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00194500"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011977970" evidence="3">
        <location>
            <begin position="18"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="262"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="355" mass="40031" checksum="07362348E1FB1CCF" modified="2017-02-15" version="1">MILYLSILIWIFNYFSSIRKNNLKIMPMIKNGRTLMERQLGPEISKTIIFRDVQKHLPRWLNYIERELFNQIDKLHENFTADGIRNFIDWMHNKSLHITAILNRSPDPSDKQFLRKTLESWEKLTSSILESSIEAYIDKYMLHNNGSEGALPNTSFTSSDNSSRVTTLPTTLLPTNSSIPLTTSSHNQEATSSATPVSSTEHYTYNNGTNSTISIEQNVTASPEISLETVTTPTSNVLPSLPSESGGMSSAVCTGFLCGPTIAAFSVPLVLLGCVLCFVLLYKHTPLGSLLGRDNKKKEKGKKRLREMAKHNIENSPETLEETKAKRSRLDKFLRAFGYDKNFPYIDEETGKENI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQN2</accession>
    <name>A0A1J1GQN2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00224200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527660.1">
        <property type="nucleotide sequence ID" value="XM_028670959.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQN2"/>
    <dbReference type="GeneID" id="39730769"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00224200"/>
    <dbReference type="OrthoDB" id="10260455at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039879">
        <property type="entry name" value="EFC10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21847">
        <property type="entry name" value="EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21847:SF1">
        <property type="entry name" value="EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="119" mass="14318" checksum="CCD9513B2498D638" modified="2017-02-15" version="1">MNENIEYIRKKKLMEIFEGLLGYIYFKKPKNIILSIINELKKLEKEKKIKNIFSNDDIEAMYAFLNLENNKYITKDKCILGLNQFLLNNKQREYMEKIKIADNINLEIFTKYAEEIINI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR68</accession>
    <name>A0A1J1GR68_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">H(+)-exporting diphosphatase</fullName>
            <ecNumber evidence="2">7.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">VP1</name>
        <name evidence="11" type="ORF">PGAL8A_00216100</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.3.1" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527579.1">
        <property type="nucleotide sequence ID" value="XM_028670870.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR68"/>
    <dbReference type="GeneID" id="39730688"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00216100"/>
    <dbReference type="OMA" id="AEMSHMG"/>
    <dbReference type="OrthoDB" id="5210at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009678">
        <property type="term" value="F:diphosphate hydrolysis-driven proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01129">
        <property type="entry name" value="PPase_energized_pump"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004131">
        <property type="entry name" value="PPase-energised_H-pump"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001960">
        <property type="entry name" value="PRK00733.3-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01104">
        <property type="entry name" value="V_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31998">
        <property type="entry name" value="K(+)-INSENSITIVE PYROPHOSPHATE-ENERGIZED PROTON PUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03030">
        <property type="entry name" value="H_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001265">
        <property type="entry name" value="H+-PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="281"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="359"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="401"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="433"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="496"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="525"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="593"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="617"/>
            <end position="636"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG94764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="718" mass="76733" checksum="F6F87B2927776713" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR95</accession>
    <name>A0A1J1GR95_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SPX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00150800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526621.1">
        <property type="nucleotide sequence ID" value="XM_028675051.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR95"/>
    <dbReference type="GeneID" id="39730032"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00150800"/>
    <dbReference type="OMA" id="KIHHEEW"/>
    <dbReference type="OrthoDB" id="6493944at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006799">
        <property type="term" value="P:polyphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07751">
        <property type="entry name" value="PolyPPase_VTC4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.100.30">
        <property type="entry name" value="VTC, catalytic tunnel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051572">
        <property type="entry name" value="VTC_Complex_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018966">
        <property type="entry name" value="VTC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042267">
        <property type="entry name" value="VTC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140:SF1">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE COMPLEX SUBUNIT 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09359">
        <property type="entry name" value="VTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="631"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="660"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="705"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="8">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="360"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="735" mass="88383" checksum="135CDDCF81A7629F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR97</accession>
    <name>A0A1J1GR97_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00221500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527633.1">
        <property type="nucleotide sequence ID" value="XM_028670929.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR97"/>
    <dbReference type="GeneID" id="39730742"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00221500"/>
    <dbReference type="OMA" id="FQKHIRL"/>
    <dbReference type="OrthoDB" id="371388at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="21"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1178" mass="143288" checksum="06D199A72513A5F5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRK1</accession>
    <name>A0A1J1GRK1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00229800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527715.1">
        <property type="nucleotide sequence ID" value="XM_028671020.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRK1"/>
    <dbReference type="GeneID" id="39730825"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00229800"/>
    <dbReference type="OMA" id="IRRRIKM"/>
    <dbReference type="OrthoDB" id="392529at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="114" mass="14149" checksum="8E467D2F0A90ECF1" modified="2017-02-15" version="1">MVGVKKRPVKKFNFEINLKNEIEEKVRSYIISDRNKMKEKYKQKRKKKIRRRIKMENKISTFVFPNSRKEKKLRLSYINKFIKKKKIIKQYLKEIRDKIRDYQNLINNNVQITN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRK4</accession>
    <name>A0A1J1GRK4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Proteasome subunit alpha type-2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00137100</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the peptidase T1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526488.1">
        <property type="nucleotide sequence ID" value="XM_028674904.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRK4"/>
    <dbReference type="GeneID" id="39729896"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00137100"/>
    <dbReference type="OMA" id="ATCIGKD"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03750">
        <property type="entry name" value="proteasome_alpha_type_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000012">
        <property type="entry name" value="Proteasome subunit alpha type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003075">
        <property type="entry name" value="PRK03996.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 7 9" id="KW-0647">Proteasome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="8">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="235" mass="26400" checksum="DB206BD294F527DF" modified="2017-02-15" version="1">MADGEYSFSLTTFSPTGKLVQIEYALNRVSNSSPALGIRAKNGVVIATEKKNPNELIEENSISKIQQISEHIGIVYSGMPGDFRVLLKKARKEAIRYSLQYGNEILVKELVKEIASIVQEFTQTGGVRPFGLSLLICGADAHGNHLYQIDPSGCYFNWKATCIGKDYQNNISFLEKRYNNDIEIEDAIHTAILTLKESYEGVMNEKNIEIGVAYNNKPFKILKPNEIKDYLIEIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRR4</accession>
    <name>A0A1J1GRR4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RNA-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00238500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527801.1">
        <property type="nucleotide sequence ID" value="XM_028671117.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRR4"/>
    <dbReference type="GeneID" id="39730913"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00238500"/>
    <dbReference type="OMA" id="IWNEMRN"/>
    <dbReference type="OrthoDB" id="10266058at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12232">
        <property type="entry name" value="RRM3_U2AF65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23139">
        <property type="entry name" value="RNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="207"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="39"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="64"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG94988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="472" mass="55002" checksum="BC5C2A32FD10D81B" modified="2017-02-15" version="1">MESEESKKKEPKSISENNDKKRVYKNEEMKRYSKDKRSSSRTRRSRSNSHGIRRNSSDNYSKGKYIKKKRRKDKSSESSHSSSPMSSESSNDNYSSDEYRRKKRKKKRENRYERSEKSDKRKKKKKSSKLNPNLSTSHERSRSRERKRRKLQAECIKRAGGFKKLADMEGHETTNVFWDGFQWVAKTNQSNLFHLDPAVMNSTRKLRRLYFGNLPLHLGLSENAFQEIVWNEMKKRKYCNDENINPVLYVWFAKDKGNYGFVEFATVEETERALTMDGMLCKGVALKVSRPNDYSTNTVKQNQNLLLQNISKQNNNILNVMNPTNINNSYSKPPPPPGAPPLSLLKDTLESNLMNQGNFSTKYLRVLEIVSKESINEEDYTTILEDIKDGFHSQGIIINAILITPKYAQNTPFDIGDVIIEFENPTSVDNSIINMSNRKYEGRVIKMEKCDEHTYNTYVKPIIKDLYEKKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRY2</accession>
    <name>A0A1J1GRY2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00263500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528042.1">
        <property type="nucleotide sequence ID" value="XM_028671384.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731164"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00263500"/>
    <dbReference type="OMA" id="NCEYVTC"/>
    <dbReference type="OrthoDB" id="376066at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="66"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1419" mass="171125" checksum="ED85E19934F6ABFD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS04</accession>
    <name>A0A1J1GS04_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TRIP4/RQT4 C2HC5-type zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00248300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527897.1">
        <property type="nucleotide sequence ID" value="XM_028671224.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS04"/>
    <dbReference type="GeneID" id="39731011"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00248300"/>
    <dbReference type="OrthoDB" id="338816at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0180022">
        <property type="term" value="C:RQC-trigger complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072344">
        <property type="term" value="P:rescue of stalled ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009349">
        <property type="entry name" value="TRIP4/RQT4_C2HC5_Znf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06221">
        <property type="entry name" value="zf-C2HC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TRIP4/RQT4 C2HC5-type zinc finger" evidence="1">
        <location>
            <begin position="295"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="569" mass="68374" checksum="8CA151D482336F30" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS55</accession>
    <name>A0A1J1GS55_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fam-g protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00251200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527923.1">
        <property type="nucleotide sequence ID" value="XM_028671252.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS55"/>
    <dbReference type="GeneID" id="39731040"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00251200"/>
    <dbReference type="OMA" id="KEMGDYQ"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009618937" description="Fam-g protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="60" mass="7417" checksum="80CB4AAAE850ED77" modified="2017-02-15" version="1">MIIIIFILLLLLYHIWNKNKNFIINFYYINSFICFNKSKRHSDIRKEMGEYKGCYSDNYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSG9</accession>
    <name>A0A1J1GSG9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">T-complex protein 1 subunit epsilon</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">CCT-epsilon</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">CCT5</name>
        <name evidence="10" type="ORF">PGAL8A_00396000</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527077.1">
        <property type="nucleotide sequence ID" value="XM_028670313.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSG9"/>
    <dbReference type="GeneID" id="39732490"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00396000"/>
    <dbReference type="OMA" id="EMAILTC"/>
    <dbReference type="OrthoDB" id="10248520at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03339">
        <property type="entry name" value="TCP1_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000003">
        <property type="entry name" value="T-complex protein 1 subunit epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012718">
        <property type="entry name" value="Chap_CCT_epsi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054827">
        <property type="entry name" value="thermosome_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02343">
        <property type="entry name" value="chap_CCT_epsi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041082">
        <property type="entry name" value="thermosome_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG94256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="535" mass="59211" checksum="3744FBFFD32F636B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GST6</accession>
    <name>A0A1J1GST6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DnaJ protein, putative</fullName>
            <ecNumber evidence="9">3.4.24.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00381900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase M3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.16" evidence="9"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526936.1">
        <property type="nucleotide sequence ID" value="XM_028670156.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GST6"/>
    <dbReference type="GeneID" id="39732349"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00381900"/>
    <dbReference type="OMA" id="HFSCYYA"/>
    <dbReference type="OrthoDB" id="534666at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006518">
        <property type="term" value="P:peptide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.10">
        <property type="entry name" value="Neurolysin, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024077">
        <property type="entry name" value="Neurolysin/TOP_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804:SF79">
        <property type="entry name" value="MITOCHONDRIAL INTERMEDIATE PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M3A/M3B catalytic" evidence="8">
        <location>
            <begin position="217"/>
            <end position="630"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="691" mass="83091" checksum="53139C8DE5985508" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT10</accession>
    <name>A0A1J1GT10_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Autophagy-related protein 18, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ATG18</name>
        <name evidence="4" type="ORF">PGAL8A_00389100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat PROPPIN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527008.1">
        <property type="nucleotide sequence ID" value="XM_028670236.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT10"/>
    <dbReference type="GeneID" id="39732421"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00389100"/>
    <dbReference type="OMA" id="GGPQCMC"/>
    <dbReference type="OrthoDB" id="1667587at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000524">
        <property type="entry name" value="Autophagy-related protein 18, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048720">
        <property type="entry name" value="PROPPIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11227">
        <property type="entry name" value="WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21032">
        <property type="entry name" value="PROPPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="380" mass="43583" checksum="24D6C71C4657B06B" modified="2017-02-15" version="1">MVSLRLDNNRYISFNQDYGCLCMANEKGFKIYNTNPFTQTYSRDLTDRNKNGLYLAEMLYRCNILAITGNKNDKKGKWAKNVLIIWDDRQMREIAKLTFSSNIIGVRLLREIIVVILEYKLCIYRLKDIILLETLNTSKNVSGLCCLSNIDKNIIIAYLSPIKGRVNIHIFEINSSDNIHEELPYINFKTNLSIYAHDNSIGCINLSNDGKLLVTSSIKGTIIRLFNTFDGTLLNEFRRGTKNAKILSLNISEDNNWLCLTSSRNTVHVFSIYKKKRPLRKVDIICKGKNMSSPAVLHYDKEAKNKKSSLKCLLPCHPYLNSEWSFAHYKLPGKKISSICAFVNDQNCIIVICSNGIIYKLRFNEHIGGEMFKISSHSFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT34</accession>
    <name>A0A1J1GT34_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nuclear transport factor 2</fullName>
            <shortName evidence="1">NTF-2</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">NTF2</name>
        <name evidence="3" type="ORF">PGAL8A_00283900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528450.1">
        <property type="nucleotide sequence ID" value="XM_028671837.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT34"/>
    <dbReference type="GeneID" id="39731372"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00283900"/>
    <dbReference type="OMA" id="HIKFSQM"/>
    <dbReference type="OrthoDB" id="6507044at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00780">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.50:FF:000011">
        <property type="entry name" value="Nuclear transport factor 2, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045875">
        <property type="entry name" value="NTF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002075">
        <property type="entry name" value="NTF2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018222">
        <property type="entry name" value="Nuclear_transport_factor_2_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12612">
        <property type="entry name" value="NUCLEAR TRANSPORT FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02136">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50177">
        <property type="entry name" value="NTF2_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="1" id="KW-0653">Protein transport</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NTF2" evidence="2">
        <location>
            <begin position="11"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU369002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="125" mass="14470" checksum="566AE12050557975" modified="2017-02-15" version="1">MDMLNPQFEEIGKEFVNHYFQCFNTGRNELAALYKDISMMSFENDQCRGTNQIIERLNKLPQTVVHKCLSLDIQPTPNNGILILVCGDIIIEENKPLKFCRTFHLCPLPSGGYFIFNDLFRFCIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT63</accession>
    <name>A0A1J1GT63_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00394700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527064.1">
        <property type="nucleotide sequence ID" value="XM_028670297.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT63"/>
    <dbReference type="GeneID" id="39732477"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00394700"/>
    <dbReference type="OrthoDB" id="360161at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00268">
        <property type="entry name" value="DEADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044742">
        <property type="entry name" value="DEAD/DEAH_RhlB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="244"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="452"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="113"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="680" mass="79843" checksum="F2EEF66D112CC78C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT90</accession>
    <name>A0A1J1GT90_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Thioredoxin-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00291000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528514.1">
        <property type="nucleotide sequence ID" value="XM_028671908.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT90"/>
    <dbReference type="GeneID" id="39731443"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00291000"/>
    <dbReference type="OMA" id="YKYENIN"/>
    <dbReference type="OrthoDB" id="376462at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004791">
        <property type="term" value="F:thioredoxin-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031397">
        <property type="term" value="P:negative regulation of protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030178">
        <property type="term" value="P:negative regulation of Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46472">
        <property type="entry name" value="NUCLEOREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46472:SF1">
        <property type="entry name" value="NUCLEOREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13905">
        <property type="entry name" value="Thioredoxin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012520577" evidence="2">
        <location>
            <begin position="23"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin-like fold" evidence="3">
        <location>
            <begin position="178"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="367"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="379"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="403"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="634" mass="76052" checksum="CDB55230193458C9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTA6</accession>
    <name>A0A1J1GTA6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">40S ribosomal protein S11, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00398700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527104.1">
        <property type="nucleotide sequence ID" value="XM_028670342.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTA6"/>
    <dbReference type="GeneID" id="39732517"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00398700"/>
    <dbReference type="OMA" id="DYEKCPF"/>
    <dbReference type="OrthoDB" id="10254436at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00364">
        <property type="entry name" value="Ribosomal_uS17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.1000:FF:000001">
        <property type="entry name" value="40S ribosomal protein S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000266">
        <property type="entry name" value="Ribosomal_uS17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028333">
        <property type="entry name" value="Ribosomal_uS17_arc/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019979">
        <property type="entry name" value="Ribosomal_uS17_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032440">
        <property type="entry name" value="Ribosomal_uS17_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006345">
        <property type="entry name" value="PRK08572.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03630">
        <property type="entry name" value="uS17_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S11 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744:SF9">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00366">
        <property type="entry name" value="Ribosomal_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16205">
        <property type="entry name" value="Ribosomal_S17_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00973">
        <property type="entry name" value="RIBOSOMALS17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00056">
        <property type="entry name" value="RIBOSOMAL_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS17 N-terminal" evidence="5">
        <location>
            <begin position="8"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG94283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="161" mass="18699" checksum="E0DA4B6DAACEA1B5" modified="2017-02-15" version="1">MATTLDVQHEKAYQKQEGACFFNSKKIKKGSKSYTRYWKKIGLGFATPKEAKEGVYVDKKCPFTGNVSIRGRILKGMVVSNKMKRTIIIRRNYLHYVKKYNRFEKRHKNIPCHCSPCFDVKEGDIVTVGQCRPLSKTVRFNVLKVEKHQIFGSAKKQFVLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTH0</accession>
    <name>A0A1J1GTH0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Proliferation-associated protein 2g4, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00299800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528594.1">
        <property type="nucleotide sequence ID" value="XM_028671997.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTH0"/>
    <dbReference type="GeneID" id="39731531"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00299800"/>
    <dbReference type="OMA" id="SRMFYSE"/>
    <dbReference type="OrthoDB" id="5876363at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01089">
        <property type="entry name" value="PA2G4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000029">
        <property type="entry name" value="Proliferation-associated 2G4, a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047113">
        <property type="entry name" value="PA2G4/ARX1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10804:SF11">
        <property type="entry name" value="PROLIFERATION-ASSOCIATED PROTEIN 2G4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10804">
        <property type="entry name" value="PROTEASE FAMILY M24 METHIONYL AMINOPEPTIDASE, AMINOPEPTIDASE P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M24" evidence="2">
        <location>
            <begin position="16"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="376" mass="42683" checksum="B427A2193637E668" modified="2017-02-15" version="1">MEKIPDTKTEEIDLEKYTHSGSIANTALKKIIEKCVDGAKICELCDYGEKIIKEELDKVYTKKEKGNKVEKGISFPVTINVNEICNNYSPTDSDEKIQNGDVVKICLGCHIDGHISIVGHTIYVGNENEIIEGPKAEVLKNSHTLSQLFLKSLKVGVNASEITKNIQKACEELNCNVISNCVSYQIKKYIMEGSKYILLKDNVDNKIEDFQIEPDDIYIIDVMVTTGDGKIKESDYKTTIYKREVQKNYHLKTNLGRSFLNEINKKFPVLPFHVKYLEDQRAALIGIPEALRHTLIKPYNVFSEKKKEYVAQFKYTVMVKEDGIRQLTGIKCSQLNNCKTSNKIQDELLKNILSSPLTAKKKKAKGETNEEKSKDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTT9</accession>
    <name>A0A1J1GTT9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amino acid transporter, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00313700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528732.1">
        <property type="nucleotide sequence ID" value="XM_028672150.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731670"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00313700"/>
    <dbReference type="OMA" id="CYFLGKN"/>
    <dbReference type="OrthoDB" id="294541at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16189:SF3">
        <property type="entry name" value="AMINO ACID TRANSPORTER TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16189">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 104-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="138"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="234"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="322"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="368"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="403"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1460"/>
            <end position="1478"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1348"/>
            <end position="1375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1479" mass="174912" checksum="53CDA2AE3FE43A0B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTU3</accession>
    <name>A0A1J1GTU3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00308300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528679.1">
        <property type="nucleotide sequence ID" value="XM_028672092.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTU3"/>
    <dbReference type="GeneID" id="39731616"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00308300"/>
    <dbReference type="OMA" id="ENYYIGH"/>
    <dbReference type="OrthoDB" id="361350at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="832" mass="100420" checksum="BE3377131C8993DC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTY1</accession>
    <name>A0A1J1GTY1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00312400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528719.1">
        <property type="nucleotide sequence ID" value="XM_028672136.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTY1"/>
    <dbReference type="GeneID" id="39731657"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00312400"/>
    <dbReference type="OMA" id="YTSMVVN"/>
    <dbReference type="OrthoDB" id="369963at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="208" mass="25009" checksum="F788BAB7D912C796" modified="2017-02-15" version="1">MNEHQWRMFEYNMSRWMIENKYILDQEEKKKFYKCANYSLGTGIANASLIYFLCKKYKNYFTPVSRFFLTFSFGVYTSMVVNKIYRRKAYTEILTSKTSMTDKAREVMNDILNTNDKNVKLSYKGINQNEENKTIENTNSYNLMDENDSQINNDFKLDDNNNTLLTEDINDNIRNEQINEIERQNSYFLKDFNEGKSVSWDEIRRRNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTY6</accession>
    <name>A0A1J1GTY6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">IMP-specific 5'-nucleotidase 1</fullName>
            <ecNumber evidence="4">3.1.3.99</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00315900</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>IMP + H2O = inosine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:27718"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="3.1.3.99"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ISN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.99" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528754.1">
        <property type="nucleotide sequence ID" value="XM_028672174.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTY6"/>
    <dbReference type="GeneID" id="39731692"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00315900"/>
    <dbReference type="OMA" id="WGVLACQ"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008253">
        <property type="term" value="F:5'-nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006190">
        <property type="term" value="P:inosine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071590">
        <property type="term" value="P:nicotinamide riboside biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071592">
        <property type="term" value="P:nicotinic acid riboside biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1240.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009453">
        <property type="entry name" value="ISN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043169">
        <property type="entry name" value="PMM_cap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28213">
        <property type="entry name" value="IMP-SPECIFIC 5'-NUCLEOTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28213:SF1">
        <property type="entry name" value="IMP-SPECIFIC 5'-NUCLEOTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06437">
        <property type="entry name" value="ISN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028836">
        <property type="entry name" value="ISN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG95946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="444" mass="51801" checksum="175B60F8DF42DA38" modified="2017-02-15" version="1">MKKLDIDVYDKIEDIHLGIYEQDQCDFLALSDRNVMNSDTKKNIIHFNNHYSYNQLKNKDSLIMFLVDILKSLFVSNCIDKNIDNVLLSIEEMFIDHYYNPLHSRLKYLIDDVGIFFTKLPISKAFHTYNKKYQITKRLYAPPTFNEVRHILNLAQILSLEDGLDLLTFDADETLYPDGHDFHDEVLASYISILLKKMNIAIVTAACYNNDAEKYQKRLENLLKYFSKHNIEDGSYKNFYVMGGESNYLFKCNEEANLYSVPEKEWIHYKKHVDDETIQDILNISQKCLEQVIKDFKLCAKIQRKEKSIGLVPEKMPSLNNKNEPKNYMIKYEVLEEAVIRIKKEIIKKKITAPYCAFNGGQDLWVDIGNKAEGLLILQKLLKIEKKKCCHIGDQFLHSGNDFPTRFCSLTLWVSNPQETKACLKSIMNLNIKSFVPEVLYESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU63</accession>
    <name>A0A1J1GU63_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Plasmepsin VIII, putative</fullName>
            <ecNumber evidence="10">3.4.17.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00225100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.17.4" evidence="10"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527669.1">
        <property type="nucleotide sequence ID" value="XM_028670969.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU63"/>
    <dbReference type="GeneID" id="39730778"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00225100"/>
    <dbReference type="OMA" id="EFWRNHH"/>
    <dbReference type="OrthoDB" id="771136at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000115">
        <property type="entry name" value="Lysosomal aspartic protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="10" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013357536" evidence="8">
        <location>
            <begin position="21"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="9">
        <location>
            <begin position="62"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="270"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="93"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG94854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="385" mass="44011" checksum="3CEB321ACC9487C1" modified="2017-02-15" version="1">MVIFFVFFVFPFVTNIFVDSLKENLRVSKCNVTEKKNEIKFEDKNKEISTIILKGGYINRQFIGEISIGNPPQAFKVLFDTGSTNLWIPSKNCYSKGCNNKRKYDHKISKNYKLIKNRNPVEILFGTGKIQMTYVSDDIHLGDIKVNNQEFGLASYMSDDPFSDMLFDGLFGLGILEDNKKKQLIYDNIPRINSKKNIFSVYYPKNVNDNGAITFGGYDKKYIEPNSEIDWFDVSSKKYWAIKMIGLKVNGVLLDICSKNNGGYCEAVIDTGTSSIAGPKDDLILLTSLLYPGKSCYNKMFLKNFSFILSDENGIHREYELTPKDYILNSFKNDPIFKVPCNFAFMPINISSNSGYLYILGQIFLQKYYAIFEKDNMKIGLAKSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUB7</accession>
    <name>A0A1J1GUB7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00329100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000057">
        <property type="protein sequence ID" value="CRG96077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528882.1">
        <property type="nucleotide sequence ID" value="XM_028672318.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUB7"/>
    <dbReference type="GeneID" id="39731820"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00329100"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="310" mass="37366" checksum="5369E8FD201B898C" modified="2017-02-15" version="1">MKTLTLYLKFTTFLLLIWMYQYFYNCDSYKTLIDKNILQIINELKYERVLTEGDIAGEKQTNAEGCQEECPTKNNEKEKKKIIWKNSRKLSNPYNLWQKFTSPALFERFKNEINGMDPKWIEEKWKNEWNQISENKVKDLSSIFQRSDISNEEKEKLILDTKTELFKLYMEFVDESKKEMRGNKTESESESEKELRDKKRESESNNEMKDHRTESESINEMIDNRTETESMKEMRENRRESKSEKEMIDNKAESESEKEMIDNKAESESEKEMRYDKTESKSRNEQGTNEVKNYKKIWVLLIVLIILRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUC3</accession>
    <name>A0A1J1GUC3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00332600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528916.1">
        <property type="nucleotide sequence ID" value="XM_028672356.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUC3"/>
    <dbReference type="GeneID" id="39731856"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00332600"/>
    <dbReference type="OMA" id="GHINCYI"/>
    <dbReference type="OrthoDB" id="372021at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012227319" evidence="2">
        <location>
            <begin position="26"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="589"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="638" mass="75751" checksum="FCC35B951D13C03D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUH8</accession>
    <name>A0A1J1GUH8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00236500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527781.1">
        <property type="nucleotide sequence ID" value="XM_028671095.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUH8"/>
    <dbReference type="GeneID" id="39730893"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00236500"/>
    <dbReference type="OMA" id="PLEVHYL"/>
    <dbReference type="OrthoDB" id="378328at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1040"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1078"/>
            <end position="1102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1118" mass="136299" checksum="32B9F69132BD0183" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUN1</accession>
    <name>A0A1J1GUN1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Myosin C, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">MyoC</name>
        <name evidence="13" type="ORF">PGAL8A_00241400</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="9">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527829.1">
        <property type="nucleotide sequence ID" value="XM_028671148.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730942"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00241400"/>
    <dbReference type="OMA" id="DLCELTH"/>
    <dbReference type="OrthoDB" id="6108017at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000146">
        <property type="term" value="F:microfilament motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14888">
        <property type="entry name" value="MYSc_Myo27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140:SF706">
        <property type="entry name" value="DILUTE CLASS UNCONVENTIONAL MYOSIN, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140">
        <property type="entry name" value="MYOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00193">
        <property type="entry name" value="MYOSINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="4 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="5 9" id="KW-0518">Myosin</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 8" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Myosin motor" evidence="12">
        <location>
            <begin position="9"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="1542"/>
            <end position="1583"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="1771"/>
            <end position="1802"/>
        </location>
    </feature>
    <feature type="region of interest" description="Actin-binding" evidence="9">
        <location>
            <begin position="591"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="716"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="958"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="1070"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="725"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="746"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="102"/>
            <end position="109"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG95016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1807" mass="209194" checksum="BE5A06995CAEF05A" modified="2017-02-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUU0</accession>
    <name>A0A1J1GUU0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00346300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529050.1">
        <property type="nucleotide sequence ID" value="XM_028672504.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUU0"/>
    <dbReference type="GeneID" id="39731993"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00346300"/>
    <dbReference type="OMA" id="NVINPNC"/>
    <dbReference type="OrthoDB" id="386288at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001289">
        <property type="entry name" value="NFYA"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51152">
        <property type="entry name" value="NFYA_HAP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="305" mass="35966" checksum="12397BF5A58F5842" modified="2017-02-15" version="1">MEKNKIINKIYGKNINNNQNISLQMLSNTMNGMHKNSNGDIERSLDMTKINSIINTNELNCNDLINNKANIGNIGNVGNEIIYVNDKQYERILKRRMRKIKQDIEKKRKVRVYRTIQKKVVPTTNSENNINLNNNFSTSLYNYDLNSNDSYMKKNENSNRYISLNENMQNIYDMKSSKNYEKNMYINDYNNYSNLNTDDDYKKYLNICEINNMNNMNNINNMNNINNMNNMNNINNMNNINNMNNMNSINNLSNMEELNNVSKMNSFDHFNNINTMNSFNQINNLNNVSNFPNTMNENFLYGQYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUW0</accession>
    <name>A0A1J1GUW0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00324000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000051">
        <property type="protein sequence ID" value="CRG96027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528835.1">
        <property type="nucleotide sequence ID" value="XM_028672265.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731773"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00324000"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="640"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="293"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="351"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="681"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="771"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1191"/>
            <end position="1252"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1456"/>
            <end position="1512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="28"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="298"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="317"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="377"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="401"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="416"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="457"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="681"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="694"/>
            <end position="703"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1653" mass="195081" checksum="328E350CD358C598" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV25</accession>
    <name>A0A1J1GV25_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Lipoyl synthase, apicoplast</fullName>
            <ecNumber evidence="10">2.8.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Lipoate synthase</fullName>
            <shortName evidence="10">LS</shortName>
            <shortName evidence="10">Lip-syn</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Lipoic acid synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">LipA</name>
        <name evidence="10" type="synonym">lipA</name>
        <name evidence="12" type="ORF">PGAL8A_00255700</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>[[Fe-S] cluster scaffold protein carrying a second [4Fe-4S](2+) cluster] + N(6)-octanoyl-L-lysyl-[protein] + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine + 4 H(+) = [[Fe-S] cluster scaffold protein] + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + 4 Fe(3+) + 2 hydrogen sulfide + 2 5'-deoxyadenosine + 2 L-methionine + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:16585"/>
            <dbReference type="Rhea" id="RHEA-COMP:9928"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:14568"/>
            <dbReference type="Rhea" id="RHEA-COMP:14569"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:33722"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:78809"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="2.8.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="10">Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Plastid</location>
            <location evidence="10">Apicoplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the radical SAM superfamily. Lipoyl synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.8" evidence="10"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527965.1">
        <property type="nucleotide sequence ID" value="XM_028671298.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV25"/>
    <dbReference type="GeneID" id="39731085"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00255700"/>
    <dbReference type="OMA" id="RSCAFCQ"/>
    <dbReference type="OrthoDB" id="3231at2759"/>
    <dbReference type="UniPathway" id="UPA00538">
        <property type="reaction ID" value="UER00593"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020011">
        <property type="term" value="C:apicoplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016992">
        <property type="term" value="F:lipoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00206">
        <property type="entry name" value="Lipoyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031691">
        <property type="entry name" value="LIAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003698">
        <property type="entry name" value="Lipoyl_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00510">
        <property type="entry name" value="lipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004019">
        <property type="entry name" value="PRK05481.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009544">
        <property type="entry name" value="PRK12928.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10949">
        <property type="entry name" value="LIPOYL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10949:SF0">
        <property type="entry name" value="LIPOYL SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16881">
        <property type="entry name" value="LIAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00271">
        <property type="entry name" value="lipoyl_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01058">
        <property type="entry name" value="lipoyl_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6 10" id="KW-0933">Apicoplast</keyword>
    <keyword evidence="7 10" id="KW-0408">Iron</keyword>
    <keyword evidence="8 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0934">Plastid</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="3 10 12" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013406709" description="Lipoyl synthase, apicoplast" evidence="10">
        <location>
            <begin position="23"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="11">
        <location>
            <begin position="179"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="408"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG95152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="438" mass="50711" checksum="973EDE5C0F2C12F9" modified="2017-02-15" version="1" precursor="true">MYFCKLCFYIYIFFLVSLKIKCDKIKNFRSEKQLSYYYIQNKNENKIYLKDFLKKENKLNYKGKVSFKKCQVFNVKSIQSECMNEHMDNIKNNMNCSEYIKLDDSKCEKKSSMNNKNMTSNGKLLTPKVGNKMPEKKPDWFHVPAPTGEKYNKLKNDLKKLKLHTVCEEAQCPNIGECWNIGTATIMLLGDTCTRGCKFCSIKTSPKPLPPDVNEPFNTAKAICEWDINYVVLTSVDRDDLPDGGADHFAKTVELIKFSRPDILIECLVSDFQGSFSSVKRLALSGLDVYAHNIETVKRLQKYVRDKRANYEQSLLVLKMAKEINPKLYTKTSIMLGLGETKEEVLEAMQNARENDIDVITFGQYLRPTKNHLSVVEYISPKLFDYYKEEGLKMGFKYIASGPLVRSSYKAGEYFMKNLVEKRKKDLHENDVKLQKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV35</accession>
    <name>A0A1J1GV35_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Erythrocyte membrane protein pfemp3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00360700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529188.1">
        <property type="nucleotide sequence ID" value="XM_028672658.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732137"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00360700"/>
    <dbReference type="OMA" id="RNMMNED"/>
    <dbReference type="OrthoDB" id="364014at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="153"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="312"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="468"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="507"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="570"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="649"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="312"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="334"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="470"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="513"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="572"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1449" mass="171863" checksum="E6AEC27F1E4DEB73" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVC0</accession>
    <name>A0A1J1GVC0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Apicoplast import protein Tic20, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TIC20</name>
        <name evidence="8" type="ORF">PGAL8A_00372200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tic20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529302.1">
        <property type="nucleotide sequence ID" value="XM_028672784.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVC0"/>
    <dbReference type="GeneID" id="39732252"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00372200"/>
    <dbReference type="OMA" id="FIKYHHM"/>
    <dbReference type="OrthoDB" id="333677at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031969">
        <property type="term" value="C:chloroplast membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005691">
        <property type="entry name" value="Tic20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33510">
        <property type="entry name" value="PROTEIN TIC 20-II, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33510:SF5">
        <property type="entry name" value="PROTEIN TIC 20-II, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16166">
        <property type="entry name" value="TIC20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012091297" evidence="7">
        <location>
            <begin position="22"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="179"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="258" mass="30540" checksum="1C01A8F221E39BBA" modified="2017-02-15" version="1">MFNFLLIFILIYFSLINNVLSFQISPKIKTYSLKKINFQNFTNYKYADNKRKVNVSYYLKKNRSTYKCIRKKKIFMSLKNKISLIFHGESDITILDKCIASISYILPFMDAVQAFVMPLVNILPTSLHKYLFQIEKINQIYSSIPFLSFVTFMGLYFLFVKDNKFKFHYFIKYHHMESLILSMFGYALALFYFRVFPYSYNDTDIFNLTILYSTMAIYFGSLIIPFFASLLGYYIEIPVLSEAIKLHIGEKKIQGEDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVP5</accession>
    <name>A0A1J1GVP5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ubiquitin-protein ligase, putative</fullName>
            <ecNumber evidence="5">6.3.2.19</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">HRD3</name>
        <name evidence="5" type="ORF">PGAL8A_00012300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sel-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.19" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528165.1">
        <property type="nucleotide sequence ID" value="XM_028671520.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVP5"/>
    <dbReference type="GeneID" id="39728645"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00012300"/>
    <dbReference type="OMA" id="YFIDGYK"/>
    <dbReference type="OrthoDB" id="27934at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050767">
        <property type="entry name" value="Sel1_AlgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102">
        <property type="entry name" value="SEL-1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11102:SF147">
        <property type="entry name" value="SEL1L ADAPTOR SUBUNIT OF ERAD E3 UBIQUITIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013221413" evidence="4">
        <location>
            <begin position="21"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="111"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="336"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="728" mass="86229" checksum="A467B4E3AA69DCBF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWD9</accession>
    <name>A0A1J1GWD9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CTP synthase</fullName>
            <ecNumber evidence="9">6.3.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">UTP--ammonia ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00281800</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>UTP + L-glutamine + ATP + H2O = CTP + L-glutamate + ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:26426"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; CTP from UDP: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the CTP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.2" evidence="9"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528429.1">
        <property type="nucleotide sequence ID" value="XM_028671814.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWD9"/>
    <dbReference type="GeneID" id="39731351"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00281800"/>
    <dbReference type="OMA" id="EFNNAYR"/>
    <dbReference type="OrthoDB" id="1739076at2759"/>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00277"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003883">
        <property type="term" value="F:CTP synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019856">
        <property type="term" value="P:pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03113">
        <property type="entry name" value="CTPS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01746">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000207">
        <property type="entry name" value="CTP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004468">
        <property type="entry name" value="CTP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017456">
        <property type="entry name" value="CTP_synthase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033828">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003792">
        <property type="entry name" value="PRK05380.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11550">
        <property type="entry name" value="CTP SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11550:SF0">
        <property type="entry name" value="CTP SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06418">
        <property type="entry name" value="CTP_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3 9 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CTP synthase N-terminal" evidence="11">
        <location>
            <begin position="12"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamine amidotransferase" evidence="10">
        <location>
            <begin position="423"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamine amidotransferase" evidence="10">
        <location>
            <begin position="670"/>
            <end position="770"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU810713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF06418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG95621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="796" mass="91719" checksum="992DD416E85DDC41" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWG0</accession>
    <name>A0A1J1GWG0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein kinase, putative</fullName>
            <ecNumber evidence="5">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00438800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529610.1">
        <property type="nucleotide sequence ID" value="XM_028673126.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWG0"/>
    <dbReference type="GeneID" id="39732921"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00438800"/>
    <dbReference type="OMA" id="WLNNISH"/>
    <dbReference type="OrthoDB" id="294378at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050167">
        <property type="entry name" value="Ser_Thr_protein_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257">
        <property type="entry name" value="SERINE-THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="776"/>
            <end position="1120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="247"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="777"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="736"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="254"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="808"/>
            <end position="821"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1131" mass="136133" checksum="6B3E8B15CE36BC57" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWR7</accession>
    <name>A0A1J1GWR7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PIR-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00266400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000035">
        <property type="protein sequence ID" value="CRG95461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528272.1">
        <property type="nucleotide sequence ID" value="XM_028671639.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWR7"/>
    <dbReference type="GeneID" id="39731193"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00266400"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="344" mass="37994" checksum="CA0FC0950EF1A834" modified="2017-02-15" version="1">MDFEVGKNNLKTELCLRSGRVLAVRQQGTRSRNVRSTRDIRRNLKVWLDFIEPGLFDRIEELKSNLTLSNAMDFSQWMNKRSGNITYVLNRVPDPTTKQILNDTLTSWRKLTDNVLLTHISDSYVDRMVIPERLAITNGLSITSASSNHTSSSNSTSSPTPTQSSNLTTSSISTSSHELNISPTAMISASDLSPTTPDFHNNSAIPTNDTSDLSTVFSTSAMDSATTIMNNSTALTPTEHGGGLTGATCKGLFCGPAFAVLPVSLALLGYTPVGKFLGRDNPKKKKAKKRLNEMPMECINSPKLLKIKKTENAKRSRLHRFLRAFGYDKNFPYIDEDIPSDQVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWT1</accession>
    <name>A0A1J1GWT1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Merozoite organizing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00429900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529523.1">
        <property type="nucleotide sequence ID" value="XM_028673029.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732831"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00429900"/>
    <dbReference type="OrthoDB" id="27187at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000793">
        <property type="term" value="C:condensed chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027165">
        <property type="entry name" value="CND3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14418:SF5">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14418">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1581"/>
            <end position="1611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1621"/>
            <end position="1640"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="761"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1318"/>
            <end position="1348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1588"/>
            <end position="1603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1688" mass="199860" checksum="884537A6A87BCC3E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWY2</accession>
    <name>A0A1J1GWY2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome c oxidase polypeptide II</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00302500</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>4 Fe(II)-[cytochrome c] + O2 + 8 H(+)(in) = 4 Fe(III)-[cytochrome c] + 2 H2O + 4 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:11436"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="7.1.1.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:11437"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome c oxidase subunit 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528621.1">
        <property type="nucleotide sequence ID" value="XM_028672027.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWY2"/>
    <dbReference type="GeneID" id="39731558"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00302500"/>
    <dbReference type="OMA" id="HAKKYYR"/>
    <dbReference type="OrthoDB" id="539285at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.420:FF:000063">
        <property type="entry name" value="Cytochrome c oxidase subunit 2, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045187">
        <property type="entry name" value="CcO_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002429">
        <property type="entry name" value="CcO_II-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001505">
        <property type="entry name" value="Copper_CuA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22888:SF9">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22888">
        <property type="entry name" value="CYTOCHROME C OXIDASE, SUBUNIT II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00116">
        <property type="entry name" value="COX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01166">
        <property type="entry name" value="CYCOXIDASEII"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00078">
        <property type="entry name" value="COX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50857">
        <property type="entry name" value="COX2_CUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cytochrome oxidase subunit II copper A binding" evidence="11">
        <location>
            <begin position="1"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG95813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="170" mass="19506" checksum="40171D5972E2858B" modified="2017-02-15" version="1">MIRSILGFNKLVTFNENKLLLKSLNEKENLKIENVRAEDYPIPEKYLEDPEKIPKYYVFQSNMVTDEDLQPGMLRQLEVDKRLTLPTRTHISFLVTATDVIHSWSIPSLGIKADAVPGRLHKVTTFILREGVYYGQCSEMCGTLHGFMPIVVEAVSPEAYAAHAKKYYRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX14</accession>
    <name>A0A1J1GX14_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zinc finger PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00304900</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528645.1">
        <property type="nucleotide sequence ID" value="XM_028672053.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731582"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00304900"/>
    <dbReference type="OMA" id="CFPRIFF"/>
    <dbReference type="OrthoDB" id="20839at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15489">
        <property type="entry name" value="PHD_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13832">
        <property type="entry name" value="zf-HC5HC2H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="559"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="592"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="622"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="650"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="675"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="718"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="765"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="823"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="859"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1074"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1153"/>
            <end position="1177"/>
        </location>
    </feature>
    <feature type="domain" description="Zinc finger PHD-type" evidence="6">
        <location>
            <begin position="3783"/>
            <end position="3864"/>
        </location>
    </feature>
    <feature type="domain" description="Zinc finger PHD-type" evidence="6">
        <location>
            <begin position="4363"/>
            <end position="4431"/>
        </location>
    </feature>
    <feature type="domain" description="Zinc finger PHD-type" evidence="6">
        <location>
            <begin position="4521"/>
            <end position="4574"/>
        </location>
    </feature>
    <feature type="domain" description="Zinc finger PHD-type" evidence="6">
        <location>
            <begin position="5172"/>
            <end position="5239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1254"/>
            <end position="1375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2034"/>
            <end position="2060"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2491"/>
            <end position="2510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="3412"/>
            <end position="3472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="5050"/>
            <end position="5072"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="5457"/>
            <end position="5574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1261"/>
            <end position="1283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1291"/>
            <end position="1321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1322"/>
            <end position="1336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1337"/>
            <end position="1347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="2036"/>
            <end position="2045"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="2051"/>
            <end position="2060"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="2499"/>
            <end position="2510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="3414"/>
            <end position="3435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="3436"/>
            <end position="3451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="3452"/>
            <end position="3463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="5051"/>
            <end position="5064"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="5467"/>
            <end position="5533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="5534"/>
            <end position="5574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="5574" mass="662793" checksum="EE8616815D2334CA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXG0</accession>
    <name>A0A1J1GXG0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein TOC75</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00456200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529785.1">
        <property type="nucleotide sequence ID" value="XM_028673321.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXG0"/>
    <dbReference type="GeneID" id="39733095"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00456200"/>
    <dbReference type="OMA" id="LNYTFYF"/>
    <dbReference type="OrthoDB" id="371888at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012227316" description="Protein TOC75" evidence="1">
        <location>
            <begin position="24"/>
            <end position="880"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="880" mass="107519" checksum="6552E2E315929F43" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXK6</accession>
    <name>A0A1J1GXK6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Merozoite TRAP-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">MTRAP</name>
        <name evidence="4" type="ORF">PGAL8A_00487900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530102.1">
        <property type="nucleotide sequence ID" value="XM_028673673.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXK6"/>
    <dbReference type="GeneID" id="39733412"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00487900"/>
    <dbReference type="OMA" id="NCPFIRE"/>
    <dbReference type="OrthoDB" id="383129at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013153654" evidence="3">
        <location>
            <begin position="18"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="409" mass="48330" checksum="15F80E4E906AE7C3" modified="2017-02-15" version="1">MNLFLISIFLILYNVKCNILSKKCESWNEWSECENDYISRTCNYDYSIRDLKSCKNCGKWGNWSPCNNGITFRYLNNCAFIKDEKECTNNNEENNKIKNENPQGMLTNLSNEDLKKDNNKNEKTVLNNNDKQYKKENEELIFNDENSSQKLEINEDNDFSETFGNITEGNKKIDNGKSVKNIHLMTPSNSFNNESNTNEIRNENPIYENTKLPFIRENKKNEIKEHNYIYDINSIKRKKGENEDNNINLHNSNNEINKSYYNKKKVKKLRDNQNIKIINQKNEIDKNISKENLNSTVRMKTYDNTFNDENKNLYNFREIHENEYDTKNNDFKGKYNDSIKFNRIYIASGLGVVLILTGGIVGYIIHKEKKTDDFPIDSKEENYEVIFNDDTSKNKSIKALYEEEFWAFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXT0</accession>
    <name>A0A1J1GXT0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MSP3-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00494900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530172.1">
        <property type="nucleotide sequence ID" value="XM_028673750.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXT0"/>
    <dbReference type="GeneID" id="39733482"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00494900"/>
    <dbReference type="OMA" id="VMGTIQT"/>
    <dbReference type="OrthoDB" id="392935at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010784">
        <property type="entry name" value="Merozoite_SPAM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07133">
        <property type="entry name" value="Merozoite_SPAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="408"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="436"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="499"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="513"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="535"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="579"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="627" mass="69627" checksum="A4A637FE8F2AB7FB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXW1</accession>
    <name>A0A1J1GXW1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N(6)-L-threonylcarbamoyladenine synthase</fullName>
            <ecNumber evidence="1">2.3.1.234</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">N6-L-threonylcarbamoyladenine synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">KAE1</name>
        <name evidence="11" type="ORF">PGAL8A_00489900</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>L-threonylcarbamoyladenylate + adenosine(37) in tRNA = N(6)-L-threonylcarbamoyladenosine(37) in tRNA + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:37059"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10163"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74418"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.3.1.234"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="9">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the KAE1 / TsaD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.234" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530122.1">
        <property type="nucleotide sequence ID" value="XM_028673695.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXW1"/>
    <dbReference type="GeneID" id="39733432"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00489900"/>
    <dbReference type="OMA" id="ESKCREY"/>
    <dbReference type="OrthoDB" id="10254073at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000408">
        <property type="term" value="C:EKC/KEOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061711">
        <property type="term" value="F:tRNA N(6)-L-threonylcarbamoyladenine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000105">
        <property type="entry name" value="Probable tRNA N6-adenosine threonylcarbamoyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000158">
        <property type="entry name" value="Probable tRNA N6-adenosine threonylcarbamoyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000210">
        <property type="entry name" value="Probable tRNA N6-adenosine threonylcarbamoyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01446">
        <property type="entry name" value="Kae1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017861">
        <property type="entry name" value="KAE1/TsaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034680">
        <property type="entry name" value="Kae1_archaea_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF14">
        <property type="entry name" value="TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00789">
        <property type="entry name" value="OSIALOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 9" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Gcp-like" evidence="10">
        <location>
            <begin position="42"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Gcp-like" evidence="10">
        <location>
            <begin position="499"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="545"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="573"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG97320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="616" mass="71382" checksum="3FD0B21282CFEC5D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXZ2</accession>
    <name>A0A1J1GXZ2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Condensin complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00500000</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CND2 (condensin subunit 2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530229.1">
        <property type="nucleotide sequence ID" value="XM_028673814.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXZ2"/>
    <dbReference type="GeneID" id="39733533"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00500000"/>
    <dbReference type="OMA" id="IDACEYK"/>
    <dbReference type="OrthoDB" id="362021at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022816">
        <property type="entry name" value="Condensin_barren_su2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13108">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13108:SF9">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05786">
        <property type="entry name" value="Cnd2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="8" id="KW-0498">Mitosis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="346"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="156"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="353"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG97428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="909" mass="105868" checksum="D0E5880C8FA0D7A8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY85</accession>
    <name>A0A1J1GY85_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1764 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00345800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529045.1">
        <property type="nucleotide sequence ID" value="XM_028672498.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY85"/>
    <dbReference type="GeneID" id="39731988"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00345800"/>
    <dbReference type="OMA" id="NLCPFDC"/>
    <dbReference type="OrthoDB" id="20835at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013885">
        <property type="entry name" value="DUF1764_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34066:SF1">
        <property type="entry name" value="DUF1764 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34066">
        <property type="entry name" value="GROWTH FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08576">
        <property type="entry name" value="DUF1764"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="120" mass="14164" checksum="9F8775EB7086920E" modified="2017-02-15" version="1">MTEKLLKKDKSEKRKKIKKKKRNKKRIEEMLEVKSNIDDIFSNIKIKNKSNKVDETEKVKKDSKSIIKNKKKKDKNQVSRKKVGERLYTPDGLPIYSMEELKMGKGGYTKECPFECNCCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY99</accession>
    <name>A0A1J1GY99_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ubiquitin-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00511100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530339.1">
        <property type="nucleotide sequence ID" value="XM_028673936.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY99"/>
    <dbReference type="GeneID" id="39733644"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00511100"/>
    <dbReference type="OMA" id="ELSTICM"/>
    <dbReference type="OrthoDB" id="380318at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17039">
        <property type="entry name" value="Ubl_ubiquitin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="1">
        <location>
            <begin position="90"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="174" mass="20413" checksum="A04906AC6C0A7BC3" modified="2017-02-15" version="1">MEELSTICMNKNNNEEKIVYIKSIGNFSKKIKFDDDCRINEVLKKNNLLNDNDTHLYQIKNKLIDLDKTFSYYNVNDGDIIYILPSPSPLPYLIYLFHQKTGRVHCIELNHEDSVNSLHKKVEKILKIKEEDQILIYSGKCLQNKKTLKEEKLARESLVTILNKKDIPEIDNEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYJ0</accession>
    <name>A0A1J1GYJ0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00488400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530107.1">
        <property type="nucleotide sequence ID" value="XM_028673679.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYJ0"/>
    <dbReference type="GeneID" id="39733417"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00488400"/>
    <dbReference type="OrthoDB" id="392023at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1264" mass="153514" checksum="DE57B72CA781CBF9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYM9</accession>
    <name>A0A1J1GYM9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00514600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530374.1">
        <property type="nucleotide sequence ID" value="XM_028673974.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733679"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00514600"/>
    <dbReference type="OMA" id="RCRKYNK"/>
    <dbReference type="OrthoDB" id="377725at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1550" mass="183595" checksum="64E64893A2219F5C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYS1</accession>
    <name>A0A1J1GYS1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00503600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530264.1">
        <property type="nucleotide sequence ID" value="XM_028673852.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYS1"/>
    <dbReference type="GeneID" id="39733569"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00503600"/>
    <dbReference type="OrthoDB" id="376496at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="90" mass="10607" checksum="AD6ADD54C9E4DB47" modified="2017-02-15" version="1">MLTLISVCTYLFYANKDYILNLVGLNNDENENKEENTTDVKTKLKNEKIRKALTEEISLSDSDLNRKKIILRTYSDVDFNIKTRNKNFRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYY5</accession>
    <name>A0A1J1GYY5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Anaphase promoting complex subunit, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00022900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the APC3/CDC27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530595.1">
        <property type="nucleotide sequence ID" value="XM_028674220.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYY5"/>
    <dbReference type="GeneID" id="39728752"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00022900"/>
    <dbReference type="OMA" id="LYSCEMK"/>
    <dbReference type="OrthoDB" id="329563at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558">
        <property type="entry name" value="CELL DIVISION CYCLE 16,23,27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12558:SF13">
        <property type="entry name" value="CELL DIVISION CYCLE PROTEIN 27 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="552"/>
            <end position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="651" mass="78463" checksum="75FBC0E9D5FEF295" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ92</accession>
    <name>A0A1J1GZ92_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00535900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530582.1">
        <property type="nucleotide sequence ID" value="XM_028674206.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ92"/>
    <dbReference type="GeneID" id="39733892"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00535900"/>
    <dbReference type="OrthoDB" id="382094at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="225"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="701" mass="83468" checksum="F5F999322F3993B2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZH5</accession>
    <name>A0A1J1GZH5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="3">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00527100</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530496.1">
        <property type="nucleotide sequence ID" value="XM_028674111.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZH5"/>
    <dbReference type="GeneID" id="39733804"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00527100"/>
    <dbReference type="OMA" id="HSTYCSN"/>
    <dbReference type="OrthoDB" id="433738at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050754">
        <property type="entry name" value="FKBP4/5/8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46512">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46512:SF9">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0697">Rotamase</keyword>
    <keyword evidence="7 10" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="269"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="10">
        <location>
            <begin position="187"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG97695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="307" mass="36487" checksum="E16F4D0283D04A6E" modified="2017-02-15" version="1">MDLCMEDIYLKNFENLDEKKVKYDNEKKNNDVDKIEYNIDNENNKHSINLKKSTNLSVEENKKDEICEKGTKKDNTKEEDNEKKSKILNDSMNLKCSDDEKETKDDANEKYNKGDYEGALKIWERGLRTINYILSKKDELKNERLQTFQKLHSTYCSNIAQGYMKLNKYSECVKYSLLAQENDKNNIKIYFRLAKGYFMLGEYDKSIKVLNEGIKINNDNSLINLLVIVKKKKQTHLEKEKYMMKYIFKSLKENPLTDDEKNKNSFLNFFYTIYSLLTFLFTFISIFYKTFLNLICSTINKCKIKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZK5</accession>
    <name>A0A1J1GZK5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">U1 small nuclear ribonucleoprotein C</fullName>
            <shortName evidence="8">U1 snRNP C</shortName>
            <shortName evidence="8">U1-C</shortName>
            <shortName evidence="8">U1C</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00523300</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">U1 snRNP is composed of the 7 core Sm proteins B/B', D1, D2, D3, E, F and G that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins U1-70K, U1-A and U1-C. U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the U1 small nuclear ribonucleoprotein C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530458.1">
        <property type="nucleotide sequence ID" value="XM_028674068.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZK5"/>
    <dbReference type="GeneID" id="39733766"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00523300"/>
    <dbReference type="OMA" id="PNNKYSR"/>
    <dbReference type="OrthoDB" id="76567at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000243">
        <property type="term" value="C:commitment complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030627">
        <property type="term" value="F:pre-mRNA 5'-splice site binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030619">
        <property type="term" value="F:U1 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000395">
        <property type="term" value="P:mRNA 5'-splice site recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000890">
        <property type="entry name" value="U1 small nuclear ribonucleoprotein C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03153">
        <property type="entry name" value="U1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000690">
        <property type="entry name" value="Matrin/U1-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013085">
        <property type="entry name" value="U1-CZ_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017340">
        <property type="entry name" value="U1_snRNP-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31148">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31148:SF1">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06220">
        <property type="entry name" value="zf-U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50171">
        <property type="entry name" value="ZF_MATRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 8" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Matrin-type" evidence="10">
        <location>
            <begin position="4"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="197"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG97657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="320" mass="37285" checksum="EDA547DF965F2171" modified="2017-02-15" version="1">MPKYYCEYCDIYLTHSSPVGRRQHIHGRKHISAKIEYFQNLLREEGITPQNFLGFLNNRNYNNSMVYPMMNYMPNNINMYMKYNQMKSYQHPLRNVNTFRLNVPNNKYSRVGYFPPNAAKCPPNQVQNINYPNNNKYPNNSLTHPNIINVNNKNSNYIGNNQLSNNLDLNDTNKNSITNTTGNPTSFNDNSCQIMNENNLNNINNNLNNDNSNLNNANNILNNTNNNLYNEINNLNNTTNSNTNNTYNNPNDITYNLKNNNNHGILNQNGLKSNYNQKDINPEVNSDNNYTYEKNLNNYNNEVNHHYNNDNVINENDNNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZN0</accession>
    <name>A0A1J1GZN0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CHCH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00046300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530829.1">
        <property type="nucleotide sequence ID" value="XM_028674481.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZN0"/>
    <dbReference type="GeneID" id="39728988"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00046300"/>
    <dbReference type="OrthoDB" id="5586401at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG98032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="82" mass="10043" checksum="5D26B4DE4BAB9EB4" modified="2017-02-15" version="1">MISLNKNLLNFLSIFKRDSKNDEFTHEYLDDKIENTKCESEYNILLECLDKYDRNWRKCQEELKIFKGCYNENNKIIIDRKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZX8</accession>
    <name>A0A1J1GZX8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">subtilisin</fullName>
            <ecNumber evidence="8">3.4.21.62</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">SUB3</name>
        <name evidence="12" type="ORF">PGAL8A_00028300</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>Hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyzes peptide amides.</text>
            <dbReference type="EC" id="3.4.21.62"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.62" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530648.1">
        <property type="nucleotide sequence ID" value="XM_028674279.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZX8"/>
    <dbReference type="GeneID" id="39728806"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00028300"/>
    <dbReference type="OMA" id="NNNVHTM"/>
    <dbReference type="OrthoDB" id="531541at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051048">
        <property type="entry name" value="Peptidase_S8/S53_subtilisin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43399:SF4">
        <property type="entry name" value="CELL WALL-ASSOCIATED PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43399">
        <property type="entry name" value="SUBTILISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 9" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0865">Zymogen</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="11">
        <location>
            <begin position="256"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="9">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="9">
        <location>
            <position position="306"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="9">
        <location>
            <position position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG97848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="547" mass="63385" checksum="0D8687E81474AF39" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H099</accession>
    <name>A0A1J1H099_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Apicoplast ribosomal protein S11, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RPS11</name>
        <name evidence="3" type="ORF">PGAL8A_API02500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <geneLocation type="apicoplast" evidence="3"/>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="LN835293">
        <property type="protein sequence ID" value="CRG98240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009325467.1">
        <property type="nucleotide sequence ID" value="NC_031963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H099"/>
    <dbReference type="GeneID" id="30315799"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_API02500"/>
    <dbReference type="OMA" id="YNGCKIS"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Apicoplast API"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.80">
        <property type="entry name" value="Ribosomal protein S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036967">
        <property type="entry name" value="Ribosomal_uS11_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53137">
        <property type="entry name" value="Translational machinery components"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0933">Apicoplast</keyword>
    <keyword evidence="3" id="KW-0934">Plastid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="133" mass="16053" checksum="9296BA03F2BC5CA5" modified="2017-02-15" version="1">MIILNNNYIIFIYFKLKLKNTLVTISKYKKYKNTYIYIKNLKNISCGHFKQFKNRLKNTILANNILIINIIKYLINKNLLNINLIFNGINFYRIHILKLLLNTKYKNKKLNIYKLFDITSIPYNGCKFSKKKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0V1</accession>
    <name>A0A1J1H0V1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00063400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530992.1">
        <property type="nucleotide sequence ID" value="XM_028674662.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0V1"/>
    <dbReference type="GeneID" id="39729159"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00063400"/>
    <dbReference type="OrthoDB" id="377572at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012859631" evidence="1">
        <location>
            <begin position="22"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="432" mass="50464" checksum="B57679DD4C283500" modified="2017-02-15" version="1">MQFFLINALLALCIFKKYINGLNYNDTIKNTRNNQFLNNDTKFEASLKNFLKKNNMNDENKEDNLIEENKDFITKQMLSGLYNSFIVDVVNNSTLQFLDNLNSEKSGSDEFQIELEESCSPFFCEKVMKAKEIERSTTDEKENSDELVDDLNSNEKEIKLHDENKNDIVQSLDSINKNNANTQEEIDAIFSRSFDGNEEKQKIILTDGDNVYILEEITQNENGLNNEEDLNNKSKEQEIKMHIPSENEENNYLEDNFLDNNLEENDDLNNLQKDSEKGIQEHNLDNNYVNEKDSNENTLDDNIFELSDEELSKKIFEDIKMNSEDKVECYNFSKNEDKCNSFKKCTYVNIDNKDTCFLDYNYMLFLKNNNCALQSKSSLLSISKDLLQNEIISRQLFQLLRNSNNNNFICDTITYSFLTNVVDNTNYEEIFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0X3</accession>
    <name>A0A1J1H0X3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Plasmodium RESA N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00450600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000079">
        <property type="protein sequence ID" value="CRG96925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529728.1">
        <property type="nucleotide sequence ID" value="XM_028673257.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0X3"/>
    <dbReference type="GeneID" id="39733039"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00450600"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="127" mass="15760" checksum="AABD389BB699477F" modified="2017-02-15" version="1">MLFYWENVCFDLGVRYSLFGREWEQENFNHWYNKISDDIKDFNDKVLAEYTLLWESCPNDKECSTFFKKKKKELSKVCKVIEDWFRKYVKKCEDEWNHFNNKNVPTFYNSIFKYNKINYKPLINNLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0Y2</accession>
    <name>A0A1J1H0Y2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PPP8</name>
        <name evidence="6" type="ORF">PGAL8A_00477300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 2">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PPP phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529997.1">
        <property type="nucleotide sequence ID" value="XM_028673557.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733306"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00477300"/>
    <dbReference type="OMA" id="CENEVLM"/>
    <dbReference type="OrthoDB" id="442428at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050341">
        <property type="entry name" value="PP1_catalytic_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668">
        <property type="entry name" value="SERINE/THREONINE PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668:SF509">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="731"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1250"/>
            <end position="1275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2073"/>
            <end position="2115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2462"/>
            <end position="2519"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="1025"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1250"/>
            <end position="1270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="2073"/>
            <end position="2082"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="2083"/>
            <end position="2115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="2471"/>
            <end position="2485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="2509"/>
            <end position="2519"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2519" mass="297896" checksum="02CCFBECA089F979" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0Z0</accession>
    <name>A0A1J1H0Z0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Reticulocyte binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00478100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530005.1">
        <property type="nucleotide sequence ID" value="XM_028673565.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0Z0"/>
    <dbReference type="GeneID" id="39733314"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00478100"/>
    <dbReference type="OrthoDB" id="10527943at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012475675" description="Reticulocyte binding protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="570" mass="67826" checksum="2EB6B034CDA97532" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0Z4</accession>
    <name>A0A1J1H0Z4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Elongation factor Tu, apicoplast</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">TUFA</name>
        <name evidence="10" type="ORF">PGAL8A_API02800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <geneLocation type="apicoplast" evidence="10"/>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Apicoplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="LN835293">
        <property type="protein sequence ID" value="CRG98243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009325470.1">
        <property type="nucleotide sequence ID" value="NC_031963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0Z4"/>
    <dbReference type="GeneID" id="30315813"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_API02800"/>
    <dbReference type="OMA" id="PFDRIDR"/>
    <dbReference type="OrthoDB" id="2067at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Apicoplast API"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020011">
        <property type="term" value="C:apicoplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070125">
        <property type="term" value="P:mitochondrial translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01884">
        <property type="entry name" value="EF_Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03697">
        <property type="entry name" value="EFTU_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03707">
        <property type="entry name" value="EFTU_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000001">
        <property type="entry name" value="Elongation factor Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001554">
        <property type="entry name" value="Translation elongation factor Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041709">
        <property type="entry name" value="EF-Tu_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050055">
        <property type="entry name" value="EF-Tu_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033720">
        <property type="entry name" value="EFTU_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000766">
        <property type="entry name" value="PRK00049.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009372">
        <property type="entry name" value="PRK12735.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009373">
        <property type="entry name" value="PRK12736.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721:SF22">
        <property type="entry name" value="ELONGATION FACTOR TU, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721">
        <property type="entry name" value="ELONGATION FACTOR TU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0933">Apicoplast</keyword>
    <keyword evidence="4 10" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0934">Plastid</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="9">
        <location>
            <begin position="10"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00071511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG98243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="409" mass="46566" checksum="60C447D510764219" modified="2017-02-15" version="1">MNNKLFLRNKQHINLGTIGHVDHGKTTLTTAISYLLNIQGLSKKYNYSDIDSAPEEKIRGITINTTHIEYETFTKHCAHIDCPGHADYIKNMIIGATQMDIAILVISIIDGIMPQTYEHLLLIKQIGIKDIIIFLNKEDLCDDIELIDFIKLEINELLIKYNFDLNYIKILTGSALNVINIIQKNKNYELIKSNIWIQKLINLINEIDNIKISTRKINDDFLMPIEDIFSITGRGTVVTGKIEQGCINLNEEIEILKFEKSSIITTVIGLEMFKKQLNQAQSGDNVGILLRNIQKKEIKRGMILSKPNKLKVSKFFISETYILTQEEGGRHKPFGIGYKPQFFIRTVDVTGEIKNIYSNNINQKIAIPGDKLTLYIELKHYIVLTLNMKFSIREGGKTIGAGIITNIIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H135</accession>
    <name>A0A1J1H135_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Heat shock protein 40, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00060000</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530962.1">
        <property type="nucleotide sequence ID" value="XM_028674628.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H135"/>
    <dbReference type="GeneID" id="39729125"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00060000"/>
    <dbReference type="OrthoDB" id="10256793at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10719">
        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000064">
        <property type="entry name" value="Molecular chaperone DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.230.10:FF:000002">
        <property type="entry name" value="Molecular chaperone DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.230.10">
        <property type="entry name" value="Heat shock protein DnaJ, cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01152">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012724">
        <property type="entry name" value="DnaJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43096">
        <property type="entry name" value="DNAJ HOMOLOG 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43096:SF52">
        <property type="entry name" value="DNAJ HOMOLOG 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="DnaJ/Hsp40 cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51188">
        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0346">Stress response</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="8">
        <location>
            <begin position="58"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="CR-type" evidence="9">
        <location>
            <begin position="187"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="6">
        <location>
            <begin position="187"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="424"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="622"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="431"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="479"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="558"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="631"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG98165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="664" mass="75668" checksum="FECF8BF78F064BE2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1A0</accession>
    <name>A0A1J1H1A0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">General transcription factor IIH subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">TFB2</name>
        <name evidence="11" type="ORF">PGAL8A_00464900</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TFB2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529872.1">
        <property type="nucleotide sequence ID" value="XM_028673417.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1A0"/>
    <dbReference type="GeneID" id="39733182"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00464900"/>
    <dbReference type="OrthoDB" id="364513at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000439">
        <property type="term" value="C:transcription factor TFIIH core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001671">
        <property type="term" value="F:ATPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040662">
        <property type="entry name" value="Tfb2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004598">
        <property type="entry name" value="TFIIH_p52/Tfb2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13152:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13152">
        <property type="entry name" value="TFIIH, POLYPEPTIDE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03849">
        <property type="entry name" value="Tfb2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18307">
        <property type="entry name" value="Tfb2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription factor Tfb2 C-terminal" evidence="10">
        <location>
            <begin position="733"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="226"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="232"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="268"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF18307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG97069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="829" mass="99589" checksum="BA325DD369F1840E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1D9</accession>
    <name>A0A1J1H1D9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00470600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529928.1">
        <property type="nucleotide sequence ID" value="XM_028673480.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1D9"/>
    <dbReference type="GeneID" id="39733239"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00470600"/>
    <dbReference type="OMA" id="YDENHTT"/>
    <dbReference type="OrthoDB" id="392657at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="497"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="164"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="210"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="335"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="649" mass="73689" checksum="886E3BEACC0A654F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1F4</accession>
    <name>A0A1J1H1F4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Coronin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00472200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the WD repeat coronin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529944.1">
        <property type="nucleotide sequence ID" value="XM_028673497.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1F4"/>
    <dbReference type="GeneID" id="39733255"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00472200"/>
    <dbReference type="OMA" id="YPPILMH"/>
    <dbReference type="OrthoDB" id="1850764at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000774">
        <property type="entry name" value="Coronin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015505">
        <property type="entry name" value="Coronin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015048">
        <property type="entry name" value="DUF1899"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10856">
        <property type="entry name" value="CORONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10856:SF0">
        <property type="entry name" value="CORONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08953">
        <property type="entry name" value="DUF1899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16300">
        <property type="entry name" value="WD40_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01166">
        <property type="entry name" value="DUF1899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01167">
        <property type="entry name" value="DUF1900"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="DUF1899" evidence="5">
        <location>
            <begin position="6"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="70"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="121"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU280818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="572" mass="66097" checksum="3EDBE43CE63D641C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1G1</accession>
    <name>A0A1J1H1G1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chitinase, putative</fullName>
            <ecNumber evidence="3">3.2.1.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CHT2</name>
        <name evidence="3" type="ORF">PGAL8A_00473200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.14" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529952.1">
        <property type="nucleotide sequence ID" value="XM_028673506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1G1"/>
    <dbReference type="GeneID" id="39733265"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00473200"/>
    <dbReference type="OMA" id="EYMCEDK"/>
    <dbReference type="OrthoDB" id="76388at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008843">
        <property type="term" value="F:endochitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011583">
        <property type="entry name" value="Chitinase_II/V-like_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00636">
        <property type="entry name" value="Glyco_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012249869" evidence="1">
        <location>
            <begin position="25"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="2">
        <location>
            <begin position="52"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="377" mass="42845" checksum="E841AA4F0CDF92A2" modified="2017-02-15" version="1">MKYSIARSFFFLSLFFFINISKNAIRGHPARPGESRKSARELIKSYKEREHGIIQGYYPSWVSYNHNMKDVNPEVNLLYLSFAKLDLSYDDINSIITTPSLFKSLIGLEYIGINEYFNDAMQLRKARPDIIMILSLGGENYQPSSLDAALNSTEKIANLVDELGFDGIDVDYEPNGSFDALNNINQADFFVKFVTKMKEYMCEDKLISMSHSSNGALSCIGFHDPTKICLDDNSPYNANYFQNPSVKPELLRGANMASAGSAIYIMNNLKDIVDIIFVQTFNYNNTNDPSIIHELYDSYAYYGRKYDYVIIMGFNMMFSDNPFKPNDKAYVKSIGDTIKKQNKLNKAADGLGLWSLSNNLAVFNENEVIQNFVEALH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H270</accession>
    <name>A0A1J1H270_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00499400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530223.1">
        <property type="nucleotide sequence ID" value="XM_028673807.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H270"/>
    <dbReference type="GeneID" id="39733527"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00499400"/>
    <dbReference type="OMA" id="GHINNDK"/>
    <dbReference type="OrthoDB" id="1367865at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.960.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08513">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00667">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="109"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="322"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="608"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="702"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="368"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="338"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="608"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="632"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="658"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="702"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="724"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="862"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="918"/>
            <end position="938"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="938" mass="112389" checksum="0541B317397110AF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2A0</accession>
    <name>A0A1J1H2A0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">V-type proton ATPase subunit H</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00502700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the V-ATPase H subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530255.1">
        <property type="nucleotide sequence ID" value="XM_028673842.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2A0"/>
    <dbReference type="GeneID" id="39733560"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00502700"/>
    <dbReference type="OMA" id="MKLCTHN"/>
    <dbReference type="OrthoDB" id="10263554at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000221">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.150">
        <property type="entry name" value="V-type ATPase, subunit H, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004908">
        <property type="entry name" value="ATPase_V1-cplx_hsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011987">
        <property type="entry name" value="ATPase_V1-cplx_hsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038497">
        <property type="entry name" value="ATPase_V1-cplx_hsu_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10698">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10698:SF0">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11698">
        <property type="entry name" value="V-ATPase_H_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03224">
        <property type="entry name" value="V-ATPase_H_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF032184">
        <property type="entry name" value="ATPase_V1_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATPase V1 complex subunit H C-terminal" evidence="6">
        <location>
            <begin position="318"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR032184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF11698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="455" mass="53954" checksum="9FCE68FA95C72E5B" modified="2017-02-15" version="1">MVNNSGISVITKIVESEQKNQKLHDSILNKMPCYDKYEEINILSSEEVELLKKFHEFEKKKKFEYFKENATIVTVLFNCLQTDFNIHLIQYVLTIFYEIIRNDGSSYCYILNILNNKNVYAYLMKLCTHNDTYIADKSSFLLSGSFCYNNSYFTETEIKDFILKIDFFNITEEGKMDIYINILKIDNYRKDIYELEQFLSIIKKNLDLANNNANKQYKSVFCVWLLTFKDCFIKKLHRNNIITVVINLFKKCRVEKIVRVCLNIIKNIMHIDDCFEIIVDNNVIQTLTVLQYDKWRDNDIYDTIVQLLHKLDQRVKNFSNFERYCHELSNGKLKWSILHTEKFWLENVMQFEKDEFKAIQQLADIIKNYAHNIVLKNESPNNKNEIDGVTVAVACFDIGEFARLYPNGKKICQKFRIKENIMILITTKDRDIVREALLCAQKIMLNNWQSISNTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2A4</accession>
    <name>A0A1J1H2A4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00503500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530263.1">
        <property type="nucleotide sequence ID" value="XM_028673851.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2A4"/>
    <dbReference type="GeneID" id="39733568"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00503500"/>
    <dbReference type="OMA" id="LCADNDY"/>
    <dbReference type="OrthoDB" id="391517at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="327" mass="38446" checksum="3FA10E4756468B63" modified="2017-02-15" version="1">MSDKKSSDENSFNIEDIKTKKKKKKKNVEIFYENELEIFSPCIDVEGKLCVISDKGDIFRYKLINIQKNQETNDSSSSSSEEEEYVDSNDGESIREKKKKKKEVEEEKYLSIDFTTKCLCSDNDFNFYVFNPITRGLMIIDKNKNIELYTDEYEDKSFTEVNNLVYDKKNNNLYLIDSGNINEENKSSLYYINKDIETMLSIDLENIFYANNICIYQKDNINSIYVCLTKENKILRLIKKGNSYIKSVFLYLNGCYSPLFICSNNTNFVILLKDLSECEKKGKIIEINSNAEIINSFFIKGNKFNGICYDYNINRYFFIEKNIIYIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2S0</accession>
    <name>A0A1J1H2S0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00022200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000112">
        <property type="protein sequence ID" value="CRG97787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530588.1">
        <property type="nucleotide sequence ID" value="XM_028674213.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728745"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00022200"/>
    <dbReference type="OMA" id="PPEIPDC"/>
    <dbReference type="OrthoDB" id="348930at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1361"/>
            <end position="1383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="394"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="457"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="678"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="930"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1012"/>
            <end position="1195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1233"/>
            <end position="1263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="414"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="457"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="486"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="511"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="534"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="566"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="678"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="694"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="930"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="943"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="971"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1012"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1041"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1066"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1089"/>
            <end position="1120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1121"/>
            <end position="1163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1173"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1233"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1249"/>
            <end position="1263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1386" mass="151038" checksum="AB53CA6269A31C29" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2U7</accession>
    <name>A0A1J1H2U7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Histone-arginine methyltransferase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00524600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530471.1">
        <property type="nucleotide sequence ID" value="XM_028674082.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2U7"/>
    <dbReference type="GeneID" id="39733779"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00524600"/>
    <dbReference type="OrthoDB" id="406152at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042054">
        <property type="term" value="F:histone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016274">
        <property type="term" value="F:protein-arginine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000278">
        <property type="entry name" value="Coactivator-associated arginine methyltransferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.160.11">
        <property type="entry name" value="Hnrnp arginine n-methyltransferase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025799">
        <property type="entry name" value="Arg_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055135">
        <property type="entry name" value="PRMT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006:SF53">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22528">
        <property type="entry name" value="PRMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51678">
        <property type="entry name" value="SAM_MT_PRMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="6">
        <location>
            <begin position="471"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="Protein arginine N-methyltransferase" evidence="7">
        <location>
            <begin position="608"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="177"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="382"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="180"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="391"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF22528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="819" mass="97650" checksum="50098BEA592796B0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2006-09-19" modified="2026-01-28" version="89" xmlns="https://uniprot.org/uniprot">
    <accession>Q0PCS0</accession>
    <name>Q0PCS0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 14">Cytochrome b</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">cytb</name>
        <name evidence="18" type="synonym">cob</name>
        <name evidence="20" type="synonym">CYTB</name>
        <name evidence="20" type="ORF">PGAL8A_MIT00300</name>
    </gene>
    <organism evidence="17">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <geneLocation type="mitochondrion" evidence="17"/>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2007" name="Parasitol. Res." volume="100" first="661" last="664">
            <title>Complete nucleotide sequences of the mitochondrial genomes of two avian malaria protozoa, Plasmodium gallinaceum and Plasmodium juxtanucleare.</title>
            <authorList>
                <person name="Omori S."/>
                <person name="Sato Y."/>
                <person name="Isobe T."/>
                <person name="Yukawa M."/>
                <person name="Murata K."/>
            </authorList>
            <dbReference type="PubMed" id="17047998"/>
            <dbReference type="DOI" id="10.1007/s00436-006-0333-6"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="18" key="2">
        <citation type="journal article" date="2011" name="Mitochondrion" volume="11" first="273" last="278">
            <title>Concatenated mitochondrial DNA of the coccidian parasite Eimeria tenella.</title>
            <authorList>
                <person name="Hikosaka K."/>
                <person name="Nakai Y."/>
                <person name="Watanabe Y."/>
                <person name="Tachibana S."/>
                <person name="Arisue N."/>
                <person name="Palacpac N.M.Q."/>
                <person name="Toyama T."/>
                <person name="Honma H."/>
                <person name="Horii T."/>
                <person name="Kita K."/>
                <person name="Tanabe K."/>
            </authorList>
            <dbReference type="PubMed" id="21047565"/>
            <dbReference type="DOI" id="10.1016/j.mito.2010.10.003"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">A8</strain>
        </source>
    </reference>
    <reference evidence="19" key="3">
        <citation type="journal article" date="2011" name="Parasitol. Int." volume="60" first="175" last="180">
            <title>Highly conserved gene arrangement of the mitochondrial genomes of 23 Plasmodium species.</title>
            <authorList>
                <person name="Hikosaka K."/>
                <person name="Watanabe Y."/>
                <person name="Kobayashi F."/>
                <person name="Waki S."/>
                <person name="Kita K."/>
                <person name="Tanabe K."/>
            </authorList>
            <dbReference type="PubMed" id="21329764"/>
            <dbReference type="DOI" id="10.1016/j.parint.2011.02.001"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">A8</strain>
        </source>
    </reference>
    <reference evidence="20 21" key="4">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="14">Binds 2 heme groups non-covalently.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the cytochrome b family.</text>
    </comment>
    <dbReference type="EMBL" id="AB250690">
        <property type="protein sequence ID" value="BAF03045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AB564276">
        <property type="protein sequence ID" value="BAJ25756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AB599930">
        <property type="protein sequence ID" value="BAK18848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LN835294">
        <property type="protein sequence ID" value="CRG98259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_717203.1">
        <property type="nucleotide sequence ID" value="NC_008288.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q0PCS0"/>
    <dbReference type="SMR" id="Q0PCS0"/>
    <dbReference type="GeneID" id="4238516"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_MIT00300"/>
    <dbReference type="OMA" id="NISAWWN"/>
    <dbReference type="OrthoDB" id="361890at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Mitochondrion MIT"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008121">
        <property type="term" value="F:quinol-cytochrome-c reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00284">
        <property type="entry name" value="Cytochrome_b_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.810.10">
        <property type="entry name" value="Cytochrome Bc1 Complex, Chain C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005798">
        <property type="entry name" value="Cyt_b/b6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036150">
        <property type="entry name" value="Cyt_b/b6_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005797">
        <property type="entry name" value="Cyt_b/b6_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027387">
        <property type="entry name" value="Cytb/b6-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048259">
        <property type="entry name" value="Cytochrome_b_N_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016174">
        <property type="entry name" value="Di-haem_cyt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19271">
        <property type="entry name" value="CYTOCHROME B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19271:SF16">
        <property type="entry name" value="CYTOCHROME B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00032">
        <property type="entry name" value="Cytochrom_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00033">
        <property type="entry name" value="Cytochrome_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81648">
        <property type="entry name" value="a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81342">
        <property type="entry name" value="Transmembrane di-heme cytochromes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51003">
        <property type="entry name" value="CYTB_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51002">
        <property type="entry name" value="CYTB_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4 14" id="KW-0349">Heme</keyword>
    <keyword evidence="11 14" id="KW-0408">Iron</keyword>
    <keyword evidence="13 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 14 17" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 14" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="25"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="278"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="315"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="341"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b/b6 N-terminal region profile" evidence="15">
        <location>
            <begin position="1"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b/b6 C-terminal region profile" evidence="16">
        <location>
            <begin position="200"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU362117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="BAF03045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="BAJ25756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="BAK18848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="CRG98259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="376" mass="43431" checksum="6511C3FF67C63BDD" modified="2006-09-19" version="1">MNYYSINLAKAHLIHYPCPLNINFLWNYGFLLGIVFFIQILTGVLLATCYTPEISYAYYSVQHILRELWSGWCFRYMHATGASFVFILTYLHILRGLNYSYSYLPLSWISGLMIFLISIVTAFMGYVLPWGQMSFWGATVITNLLYFIPGLVSWICGGYLVSDPTLKRFFVLHFTFPFIALCIVFIHIFFLHLQGSTNPLGYDTALKIPFYPNLLSLDIKGFNNVLVLFLAQSLFGILPLSHPDNAITVDRYATPLHIVPEWYFLPFYAMLKTIPNKTAGLLVMLASLQILFLLAEQRNLTTLIQFKFAFGAREYSVPTIWFICSFYALLWIGCQLPQDIYILYGRLFIILFFFSGLFTLVQSKRTHYDYSSQANI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL52</accession>
    <name>A0A1J1GL52_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00074700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525865.1">
        <property type="nucleotide sequence ID" value="XM_028675100.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL52"/>
    <dbReference type="GeneID" id="39729272"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00074700"/>
    <dbReference type="OrthoDB" id="385233at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="174" mass="20346" checksum="FB3EE335AED404DC" modified="2017-02-15" version="1">MSKTCELNNNVKIYIRSNSRDFNGSDESTEICIQEEFDIDNGTIINVDEIEENVKDLKFLGEDSPKKLKKDINDESYCVNEEFIYNCFCNINELSIKCILRFMADCFSFICAVCIWGILDDIFILMSKDNNFAKLYYYLIFTIIFAAITCSFNYYFSKCARKNNFIYDNIESKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLF3</accession>
    <name>A0A1J1GLF3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Generative cell specific-1/HAP2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PGAL8A_00085900</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HAP2/GCS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525977.1">
        <property type="nucleotide sequence ID" value="XM_028671100.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLF3"/>
    <dbReference type="GeneID" id="39729383"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00085900"/>
    <dbReference type="OrthoDB" id="377660at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007338">
        <property type="term" value="P:single fertilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040326">
        <property type="entry name" value="HAP2/GCS1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31764:SF0">
        <property type="entry name" value="GENERATIVE CELL SPECIFIC-1_HAP2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31764">
        <property type="entry name" value="PROTEIN HAPLESS 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0278">Fertilization</keyword>
    <keyword evidence="7" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0732">Signal</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009618921" description="Generative cell specific-1/HAP2 domain-containing protein" evidence="13">
        <location>
            <begin position="23"/>
            <end position="1176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="681"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="359"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="824"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="836"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="886"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="897"/>
            <end position="908"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG93155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1176" mass="142568" checksum="73F96C0EA2B5C0A8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLK3</accession>
    <name>A0A1J1GLK3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ribosome biogenesis protein BRX1 homolog, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00095500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the BRX1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526071.1">
        <property type="nucleotide sequence ID" value="XM_028672143.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLK3"/>
    <dbReference type="GeneID" id="39729479"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00095500"/>
    <dbReference type="OMA" id="YMWLANA"/>
    <dbReference type="OrthoDB" id="1638493at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007109">
        <property type="entry name" value="Brix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026532">
        <property type="entry name" value="BRX1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13634">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13634:SF0">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BRX1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04427">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00879">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50833">
        <property type="entry name" value="BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Brix" evidence="6">
        <location>
            <begin position="176"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="9"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="428" mass="51226" checksum="64FC35C542569FFD" modified="2017-02-15" version="1">MYNNKEKKRKEEFYEREKDTDNKRKKKMINNKILKSTLSNKKSINKKIEKNKTKKNLLKAGGLIDKKINFNEETNKKNKKKNIKKNRIVKNGSNNKKKHIGISGNIKNGKKVVAKKKINMNENNTNNINEKEQVKKGVNEQIDDEKDRYLLKIDEDPYLLKDAKYIKKSELWKNKQRVLIVRSPLKKKNCKSFIENLKLLLPHHKIENKWDKKLNKSELSEISYSRNCNNIIFFDVKKKRYCLWICKNLTGPSLYFEILDYIPLHSLIFSGNCLLYSRPLLIFSKHFDELDHLKIIKEMFIHVFGTPNYHPLSKPFYDHCYNFFYINNLIYFRHYQILPITLADSNNINKQKLVEIGPKFTLHIIKIFEECFKGRILYENVKYKNYVTPQQMKLDQNLKKKMINIKKKEKKIKKIKSINRLIKTDIDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLK7</accession>
    <name>A0A1J1GLK7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Thrombospondin-related sporozoite protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">TRSP</name>
        <name evidence="6" type="ORF">PGAL8A_00100000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526116.1">
        <property type="nucleotide sequence ID" value="XM_028672644.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLK7"/>
    <dbReference type="GeneID" id="39729524"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00100000"/>
    <dbReference type="OMA" id="CDQWTEW"/>
    <dbReference type="OrthoDB" id="446173at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.100.10">
        <property type="entry name" value="Thrombospondin type-1 (TSP1) repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043973">
        <property type="entry name" value="TSP1_CCN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000884">
        <property type="entry name" value="TSP1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036383">
        <property type="entry name" value="TSP1_rpt_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19035">
        <property type="entry name" value="TSP1_CCN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00209">
        <property type="entry name" value="TSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82895">
        <property type="entry name" value="TSP-1 type 1 repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50092">
        <property type="entry name" value="TSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012656045" evidence="4">
        <location>
            <begin position="25"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="134"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="CCN TSP1" evidence="5">
        <location>
            <begin position="58"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF19035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="162" mass="18999" checksum="3848AA1CA5181224" modified="2017-02-15" version="1">MLINISIYFFLLYLFKSHLNSIFGYNDNPSIKFIEPNKLLYDDSVIKNRILKEDNPHCEHWSEWTSCSKTCDVGVKMRVKTSSNKDYFEECSKISETSICLLRKCSESDYEGNEYETKNYEKKKEKKNSILKKYLLIFGIISVVNILLLLICVIVSLKKKII</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLL2</accession>
    <name>A0A1J1GLL2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methionine aminopeptidase 1c, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">METAP1c</name>
        <name evidence="2" type="ORF">PGAL8A_00080500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525923.1">
        <property type="nucleotide sequence ID" value="XM_028670499.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLL2"/>
    <dbReference type="GeneID" id="39729329"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00080500"/>
    <dbReference type="OrthoDB" id="3209743at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43330">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43330:SF7">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M24" evidence="1">
        <location>
            <begin position="208"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M24" evidence="1">
        <location>
            <begin position="473"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="620" mass="74961" checksum="EAC781D017CC3FF3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM32</accession>
    <name>A0A1J1GM32_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00109200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526209.1">
        <property type="nucleotide sequence ID" value="XM_028673677.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729618"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00109200"/>
    <dbReference type="OMA" id="FFFYEHV"/>
    <dbReference type="OrthoDB" id="392851at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1830"/>
            <end position="1848"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1854"/>
            <end position="1872"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="803"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="813"/>
            <end position="822"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2128" mass="255189" checksum="1793E888A76A556A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM64</accession>
    <name>A0A1J1GM64_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Centrin-1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CEN1</name>
        <name evidence="8" type="ORF">PGAL8A_00103100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the centrin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526147.1">
        <property type="nucleotide sequence ID" value="XM_028672988.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM64"/>
    <dbReference type="GeneID" id="39729556"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00103100"/>
    <dbReference type="OMA" id="CIEAREF"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000077">
        <property type="entry name" value="Centrin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000070">
        <property type="entry name" value="Centrin-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF59">
        <property type="entry name" value="EF-HAND SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="17"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="53"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="90"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="126"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="161" mass="18757" checksum="27E5E3C22765DE17" modified="2017-02-15" version="1">MVRNANNRNKRNELNEEQKLEIKEAFDLFDTNGTGRIDAKELKVAMRALGFEPKKEDIRKIISDVDKDGSGTIDFNDFLDIMTIKMSERDPKEEILKAFRLFDDDETGKISFKNLKRVAKELGENITDEEIQEMIDEADRDGDGEINEEEFMRIMKKTNLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM87</accession>
    <name>A0A1J1GM87_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00125900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526374.1">
        <property type="nucleotide sequence ID" value="XM_028674776.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM87"/>
    <dbReference type="GeneID" id="39729784"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00125900"/>
    <dbReference type="OrthoDB" id="407066at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="323" mass="38146" checksum="30332BBC2904E0EC" modified="2017-02-15" version="1">MYFFKMTSSSLDTKKCLNSILFVMKLRNFNKWLIKKNEINHICKRNFGVSGSYGYSIFAKEGNNDSNVNKNNLHQYEEKYIVNDLIKKKNFYFTKWPGQVSKLGASYFFNKNYNMGFYHMLIEEEDKIKKDIALISSCNEKSIQNKKIENKMKDLTCGYSVQIVLSGKGVKCYYEDINYTPISIQYRNNIKQYYNFKNPLKELQMLNDNTHKNVEENKNNKENKTSMEEKDNSYKTKKVKKLFVRLGIGTKNIDITRILTMHKKYVNIHVDKTGTIINVYGYNKKYVGSVSHRLYKIVKMNVYTMKGGYVYLHKPKQKIPKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM89</accession>
    <name>A0A1J1GM89_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00117400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526290.1">
        <property type="nucleotide sequence ID" value="XM_028674577.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM89"/>
    <dbReference type="GeneID" id="39729699"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00117400"/>
    <dbReference type="OrthoDB" id="375714at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48031:SF2">
        <property type="entry name" value="RNA-BINDING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48031">
        <property type="entry name" value="SRA STEM-LOOP-INTERACTING RNA-BINDING PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="150"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1037" mass="124313" checksum="786C4023EB9B0E0F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMI0</accession>
    <name>A0A1J1GMI0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00124600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526361.1">
        <property type="nucleotide sequence ID" value="XM_028674762.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729771"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00124600"/>
    <dbReference type="OMA" id="QHDFLYY"/>
    <dbReference type="OrthoDB" id="371857at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3085"/>
            <end position="3104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3962"/>
            <end position="3989"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="4335" mass="525216" checksum="483252BF8A206F14" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMM4</accession>
    <name>A0A1J1GMM4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HTH OST-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00136200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526479.1">
        <property type="nucleotide sequence ID" value="XM_028674894.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729887"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00136200"/>
    <dbReference type="OMA" id="NFNYEIC"/>
    <dbReference type="OrthoDB" id="361803at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08824">
        <property type="entry name" value="LOTUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025605">
        <property type="entry name" value="OST-HTH/LOTUS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51644">
        <property type="entry name" value="HTH_OST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH OST-type" evidence="3">
        <location>
            <begin position="1068"/>
            <end position="1145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1174"/>
            <end position="1286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1922"/>
            <end position="1981"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2505"/>
            <end position="2562"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1554"/>
            <end position="1603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1180"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1209"/>
            <end position="1254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1255"/>
            <end position="1264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1924"/>
            <end position="1981"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2511"/>
            <end position="2562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2998" mass="353944" checksum="5773E4A800750FBE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMZ2</accession>
    <name>A0A1J1GMZ2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Growth arrest-specific protein 8 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00153400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526646.1">
        <property type="nucleotide sequence ID" value="XM_028675079.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMZ2"/>
    <dbReference type="GeneID" id="39730058"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00153400"/>
    <dbReference type="OMA" id="MKHLQYE"/>
    <dbReference type="OrthoDB" id="384300at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031514">
        <property type="term" value="C:motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048870">
        <property type="term" value="P:cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039308">
        <property type="entry name" value="GAS8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025593">
        <property type="entry name" value="GAS8_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31543">
        <property type="entry name" value="DYNEIN REGULATORY COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31543:SF1">
        <property type="entry name" value="HECT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13851">
        <property type="entry name" value="GAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Growth arrest-specific protein 8" evidence="2">
        <location>
            <begin position="209"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="227"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="441" mass="53421" checksum="B864578BAA89C7FC" modified="2017-02-15" version="1">MKNTKKLKSKKKTEKETLINELSSINKEIEDEKKNVEDINSKIKNIDDNIFLGYHDLKILKLELKNKEIELEENKAFKLLSSRKIENIINRYVLKCYETFLDNLTKNEIDIYEHSRTAEIEKKNQQSYKDYDKLINVTNIQHLNKLNSIILSQNELIDEINRRFTSNLKEMRKNYSKKINLERDKLDKKRQKTIFNLQKDKNENIKNILVEYNEKILNTQNYFKLILNDQLEMIQKLEDEKLNKKKNYFSKIKYLEEFKKNISIHKKKLENLDKDVKLLEKNINDYEMLKINLKKIKEKRKKQLKVLEELKLETDVKKMLLTRISKEYEELFNKNKMKLYSYLQKLLLENYFLETKMKLKNESLEINTIELKKWQESFDPKQNEILNKVLNDKFQNFENLKKGVENMIDLNEKNKESYESLMHLNYYSNDDLDVLKRENAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMZ8</accession>
    <name>A0A1J1GMZ8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetylglucosaminylphosphatidylinositol deacetylase</fullName>
            <ecNumber evidence="2">3.5.1.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00153200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PIGL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.89" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526644.1">
        <property type="nucleotide sequence ID" value="XM_028675076.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMZ8"/>
    <dbReference type="GeneID" id="39730056"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00153200"/>
    <dbReference type="OMA" id="YVLESVN"/>
    <dbReference type="OrthoDB" id="440160at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000225">
        <property type="term" value="F:N-acetylglucosaminylphosphatidylinositol deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10320">
        <property type="entry name" value="LmbE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003737">
        <property type="entry name" value="GlcNAc_PI_deacetylase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024078">
        <property type="entry name" value="LmbE-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993:SF11">
        <property type="entry name" value="N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993">
        <property type="entry name" value="N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02585">
        <property type="entry name" value="PIG-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102588">
        <property type="entry name" value="LmbE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="199"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="232" mass="27747" checksum="9A96EE85A7602412" modified="2017-02-15" version="1">MDFKKILFTCFIIILICILFSYLEVKKNRFLEFLKKKKNICLIIAHPDDEIMFFFPTLKFLLDKKKKNEIFLLSLSNGNYYGYGKIREKEFFNIWSYLGGEKGNCKILNNPKIQDGWDYWDEKDTSNILNDYCSKHNIKTILTFDNYGISGHPNHISIFNSIRLLSKIKDINIFILNSTNIIHKYMGFLSFPFLLHKSYLISFFNPLLLLRLMFLYKSQFVYYRILFCIFSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNF4</accession>
    <name>A0A1J1GNF4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00170800</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the DEAD box helicase family. DEAH subfamily. PRP16 sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526822.1">
        <property type="nucleotide sequence ID" value="XM_028670029.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNF4"/>
    <dbReference type="GeneID" id="39730235"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00170800"/>
    <dbReference type="OMA" id="VDVMFHR"/>
    <dbReference type="OrthoDB" id="10253254at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001849">
        <property type="entry name" value="Helicase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1080:FF:000001">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001369">
        <property type="entry name" value="Putative pre-mRNA splicing factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF91">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE PRP16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="446"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="12">
        <location>
            <begin position="672"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="136"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="166"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG94001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1100" mass="128576" checksum="27490B39C4FACC15" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNL0</accession>
    <name>A0A1J1GNL0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00177500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000021">
        <property type="protein sequence ID" value="CRG94063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526884.1">
        <property type="nucleotide sequence ID" value="XM_028670098.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNL0"/>
    <dbReference type="GeneID" id="39730302"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00177500"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="120" mass="14280" checksum="63A5CFE9BFCEA983" modified="2017-02-15" version="1">MKPFINQYSKYNSLSEIKNDEKFTKSQRTIGNPIKITVLRFILTTIRHQLIKELHQISLTKRIDMLNERELLKKKILYFDKKYGENLLHDQLEQALAVILSEKGLDKLPEFFPCVNRNLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNT0</accession>
    <name>A0A1J1GNT0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DnaJ protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00381800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526935.1">
        <property type="nucleotide sequence ID" value="XM_028670154.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNT0"/>
    <dbReference type="GeneID" id="39732348"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00381800"/>
    <dbReference type="OMA" id="DTCGEEF"/>
    <dbReference type="OrthoDB" id="5894at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051964">
        <property type="entry name" value="Chaperone_stress_response"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054076">
        <property type="entry name" value="ZUO1-like_ZHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44029">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44029:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21884">
        <property type="entry name" value="ZUO1-like_ZHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="6">
        <location>
            <begin position="8"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="377"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="672"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="275"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="534"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="606"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="313"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="534"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="606"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="625"/>
            <end position="636"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="702" mass="84694" checksum="5F6F9C32EE2D7E46" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP48</accession>
    <name>A0A1J1GP48_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Nucleolar preribosomal GTPase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00076100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525877.1">
        <property type="nucleotide sequence ID" value="XM_028669989.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP48"/>
    <dbReference type="GeneID" id="39729286"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00076100"/>
    <dbReference type="OrthoDB" id="391988at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01849">
        <property type="entry name" value="YlqF_related_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014813">
        <property type="entry name" value="Gnl3_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050755">
        <property type="entry name" value="TRAFAC_YlqF/YawG_RiboMat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11089">
        <property type="entry name" value="GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11089:SF30">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN-LIKE 3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08701">
        <property type="entry name" value="GN3L_Grn1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Guanine nucleotide-binding protein-like 3 N-terminal" evidence="5">
        <location>
            <begin position="13"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="482" mass="57160" checksum="9F32076657A3DD49" modified="2017-02-15" version="1">MVKLKKTSRRQTLKQKYAIIKKVAAHKKKLKKIIKKTNIHNRRSTKNSLKIPECIFKKSILKNIKTIAESKKNKNLVKCTEIKIDDFNESTIKNVKYLLENSLKDDSDDGISNEYLENMNFKDYVHLNFNIKMKLFEKVKNENYSKLNDKYLFIDNLIEVIRNSDALFYIVDVRNPLIYLDKDIIDFIKLCKKEIIIVLNKCDLVDSGVIQQWLTYFRNYFITLPFICFIKKIPNYLNKNKLPEKLYDHFINKSYVKYIKALFKDTKITYGVIGHIYTGRNSFIHTLLNEMNCNNKIKGTDIKIDENINIYGKIGLILKKDLKGMELIKKLHSLDKKEVISLLNEFLLCLNGKNLIKVLSILKENHIINENQLHFSSNDNKLEKKEKKNRIIHSFLYENGENNNINSKNMQKLYNKLFLNKILYYIIPKSKITCFSENSDFLYHFGNLNDDVYHKIDEFIFSQKKKYGNYIIIKSDKFNFYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP86</accession>
    <name>A0A1J1GP86_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00400900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527126.1">
        <property type="nucleotide sequence ID" value="XM_028670367.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP86"/>
    <dbReference type="GeneID" id="39732539"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00400900"/>
    <dbReference type="OMA" id="DKSHENN"/>
    <dbReference type="OrthoDB" id="377882at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="222" mass="26520" checksum="88E12E9E926BBF74" modified="2017-02-15" version="1">MYQVKLSIFYIIFLLQFIVAYSYSNTKVNENGNILSSNLSIKNKKNNFKNLNSGDIIDAKKEKNDIKIRKNMNKLYNTLFPDDIEKKNEKSNFDNKYEKEHFEDNSYRINIPIDEKDLNNKKLDKKSDTLKNTELFNNEMKIENIKNGDEITINKQNTFGILGNGEKMKSESKFAIFNYLKDFFQNSSYIKNFRNYIEIFFNKYDQRIMESTIFFNFDETLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP93</accession>
    <name>A0A1J1GP93_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00382000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526937.1">
        <property type="nucleotide sequence ID" value="XM_028670157.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP93"/>
    <dbReference type="GeneID" id="39732350"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00382000"/>
    <dbReference type="OrthoDB" id="372340at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="226" mass="27142" checksum="8D123FE8DE5A1A29" modified="2017-02-15" version="1">MSDNYHFLQLCNIYKDSRNKWPLRINKLNFNIDNYKTVKTKIFLYILWNTVIFTYLLEFFMNLLFAIYMPYINTLSKTIFFFSIFDSIIVIILTCRGFYAYSNDKSNMLHKSAKFFFMLSIWCFIKLLVYVIHTLSFALITNEKINNELYYYGSKSVYFSYFMEIIITVNIIKFVLTLFTGQKIQYIVSCIRTSTILKSKIRKDLEKQSFLFDDFTYGTFISDLKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPA8</accession>
    <name>A0A1J1GPA8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Secreted protein with altered thrombospondin repeat domain, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">SPATR</name>
        <name evidence="2" type="ORF">PGAL8A_00403300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527150.1">
        <property type="nucleotide sequence ID" value="XM_028670393.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPA8"/>
    <dbReference type="GeneID" id="39732563"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00403300"/>
    <dbReference type="OMA" id="PRGYIMC"/>
    <dbReference type="OrthoDB" id="504708at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012859625" evidence="1">
        <location>
            <begin position="19"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="246" mass="29094" checksum="F51571D01950590A" modified="2017-02-15" version="1">MKISCFLFFSIFFYFAQNITLELNRKSSRKNSLDISDENEKKKNKWLNLDPEINGNTCVIFSAKEGDLQNCWCPRGYIMCNEEDVTDIQVKLNQIKNEMERKRATPLWMQRLCDNSKDKGFKNMSVVIDYELAVICKEGSDKEHPDFEIIGASGYITKEEMQQKEKENPLYVPRKCTVNSFYLCRKVENDNVNCKYSPWSEWDTCIDKKQKRNRKVLRSNQNNNNFCLWNNKIIPRNIVEEIKSCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPG8</accession>
    <name>A0A1J1GPG8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cyclin-dependent kinase 2 homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Cell division control protein 2 homolog</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">cdc2-related kinase 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">CRK3</name>
        <name evidence="15" type="ORF">PGAL8A_00088700</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">May form a complex composed of at least the catalytic subunit CRK2 and a cyclin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526005.1">
        <property type="nucleotide sequence ID" value="XM_028671410.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729411"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00088700"/>
    <dbReference type="OMA" id="SFMTKNY"/>
    <dbReference type="OrthoDB" id="387075at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008353">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032968">
        <property type="term" value="P:positive regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000624">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF546">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="420"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="527"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1038"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1176"/>
            <end position="1435"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="950"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="527"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="548"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1041"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1080"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1176"/>
            <end position="1325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1332"/>
            <end position="1396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1412"/>
            <end position="1429"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="449"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00041902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00042858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG93183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1435" mass="172868" checksum="1008CEC3E3E0C407" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPK4</accession>
    <name>A0A1J1GPK4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Autophagy-related protein 11, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ATG11</name>
        <name evidence="3" type="ORF">PGAL8A_00407400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527191.1">
        <property type="nucleotide sequence ID" value="XM_028670439.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732604"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00407400"/>
    <dbReference type="OMA" id="VQTELYI"/>
    <dbReference type="OrthoDB" id="372915at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="110"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="200"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="298"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="398"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="524"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="840"/>
            <end position="1241"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1293"/>
            <end position="1345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1406" mass="168329" checksum="EAB5B1B4F273CFE2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPW8</accession>
    <name>A0A1J1GPW8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00000600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000005">
        <property type="protein sequence ID" value="CRG93066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525888.1">
        <property type="nucleotide sequence ID" value="XM_028670111.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPW8"/>
    <dbReference type="GeneID" id="39728528"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00000600"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="136" mass="16072" checksum="FF1A90AE776B30DB" modified="2017-02-15" version="1">MESEENYDPYSLEDDDYIQNSYVTIRLSDQDIYTANYSNLHIPNHSEILIDEENVISNNSPDNQGVYIPNNQRTSYFECFLGHFALYTTLLFLTLRHLFLDCYRGLKRLKRERFDNNNDNSDKKSLIASVINEEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ02</accession>
    <name>A0A1J1GQ02_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">UMP-CMP kinase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00107200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526189.1">
        <property type="nucleotide sequence ID" value="XM_028673455.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ02"/>
    <dbReference type="GeneID" id="39729598"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00107200"/>
    <dbReference type="OMA" id="FLYCDED"/>
    <dbReference type="OrthoDB" id="442176at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019205">
        <property type="term" value="F:nucleobase-containing compound kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="158"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="351" mass="42035" checksum="67DA8AB586FCE7FF" modified="2017-02-15" version="1">MILVNFSKVFFVENLNYSKNKKKIFYLNRTNVYYKKGDNFKSLFKKNKITRIINNTNFVFNTRKFNSYQYLETFFINNKFIMSRDQPLVIFMLGGPGSGKGTQCKLIQEKFDFIHISAGDCLREYLIKCEKNEVNKKHQSIVEDCINNGKIVPVNITLELMKIKIESEIEKRKQLEHEQIEEREEIKEKKNSFSFNLLDENIYLKNTDMEKYHEKLKYENNIYENKEVLEILKKNKLKQKAKYKFIIDGFPRNFDNFNGWIKIIGNYAYVHLCLFLYCDEEVMIERCISRGLVSGRVDDNMETLKKRFETHKNECIPIINLFLNENKCIFINANKNIEHVWNDIQYIFSNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ33</accession>
    <name>A0A1J1GQ33_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fam-b protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00194800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527367.1">
        <property type="nucleotide sequence ID" value="XM_028670634.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ33"/>
    <dbReference type="GeneID" id="39730474"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00194800"/>
    <dbReference type="OMA" id="SERMNEF"/>
    <dbReference type="OrthoDB" id="10537586at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012181810" description="Fam-b protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="293"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="320" mass="37146" checksum="82DF0ED04B983204" modified="2017-02-15" version="1">MKSGLFWIVILNICFSLFGVSYEEDIGTESNKLDSNLIDSSFYSNLRNANKNEEMVYELENLDLGENEYDTEEINLEIKNEILSNPPENTEIHNLKGPRGGDPTISHILNNPTLKGFEGRLFIQRRKLLNMKKKLDEIHKLLSERMNEFCSHLHKRNHNYTDNIREEEIHEISYKNNSEYIKMLLYTKKILEFLKSSKLDEKIYKSYYYPIIQKNIGVQRYIKNLVNNSMDTIDFIYKKKGFVGDIEANIKSKSSSDLEKYLKSKEFSGSVMNTLYDVDISDDGIFSTTKAKITLGILGCILVGGGIAFAFYYKKMMFKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ41</accession>
    <name>A0A1J1GQ41_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00085000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525968.1">
        <property type="nucleotide sequence ID" value="XM_028670999.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ41"/>
    <dbReference type="GeneID" id="39729374"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00085000"/>
    <dbReference type="OrthoDB" id="372706at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="107" mass="12533" checksum="85701C1B8AAD7C3F" modified="2017-02-15" version="1">MQKNIPEKDNQNELKSDLKENKNDTKSNEINEDNIYIFDEPDDELEEFEEMGSVALNVDTDLENWEEDWGAAGWDDDDDDDDKFILKVESELQKFRASLDAEKDVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQI3</accession>
    <name>A0A1J1GQI3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00101200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526128.1">
        <property type="nucleotide sequence ID" value="XM_028672777.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729537"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00101200"/>
    <dbReference type="OMA" id="FKMISEC"/>
    <dbReference type="OrthoDB" id="10479236at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="723"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="749"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="868"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2003"/>
            <end position="2021"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2044"/>
            <end position="2065"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2077"/>
            <end position="2099"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1462"/>
            <end position="1489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2130" mass="260638" checksum="C1288FA34F88061B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQK5</accession>
    <name>A0A1J1GQK5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Aminopeptidase P, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00213600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the peptidase M24B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527554.1">
        <property type="nucleotide sequence ID" value="XM_028670841.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQK5"/>
    <dbReference type="GeneID" id="39730663"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00213600"/>
    <dbReference type="OMA" id="EPGMILS"/>
    <dbReference type="OrthoDB" id="9995434at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01085">
        <property type="entry name" value="APP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.230.10:FF:000009">
        <property type="entry name" value="xaa-Pro aminopeptidase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000587">
        <property type="entry name" value="Creatinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033740">
        <property type="entry name" value="Pept_M24B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032416">
        <property type="entry name" value="Peptidase_M24_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001131">
        <property type="entry name" value="Peptidase_M24B_aminopep-P_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050422">
        <property type="entry name" value="X-Pro_aminopeptidase_P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43763">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43763:SF6">
        <property type="entry name" value="XAA-PRO AMINOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01321">
        <property type="entry name" value="Creatinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16189">
        <property type="entry name" value="Creatinase_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16188">
        <property type="entry name" value="Peptidase_M24_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="Creatinase/prolidase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00491">
        <property type="entry name" value="PROLINE_PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="domain" description="Creatinase N-terminal" evidence="7">
        <location>
            <begin position="123"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M24" evidence="6">
        <location>
            <begin position="478"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M24 C-terminal" evidence="8">
        <location>
            <begin position="702"/>
            <end position="769"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="771" mass="90078" checksum="137057081DF26F3F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQR0</accession>
    <name>A0A1J1GQR0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Calponin-homology (CH) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00108300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526200.1">
        <property type="nucleotide sequence ID" value="XM_028673577.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQR0"/>
    <dbReference type="GeneID" id="39729609"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00108300"/>
    <dbReference type="OrthoDB" id="370524at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="3">
        <location>
            <begin position="37"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="411"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="696"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="501"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="425"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="701"/>
            <end position="717"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="717" mass="85789" checksum="F8D58FF74CBAF8EE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQS8</accession>
    <name>A0A1J1GQS8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Elongation of fatty acids protein</fullName>
            <ecNumber evidence="10">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00134400</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>an acyl-CoA + malonyl-CoA + H(+) = a 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:50252"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:50253"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the ELO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="10"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526461.1">
        <property type="nucleotide sequence ID" value="XM_028674873.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQS8"/>
    <dbReference type="GeneID" id="39729869"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00134400"/>
    <dbReference type="OMA" id="EFMQNAD"/>
    <dbReference type="OrthoDB" id="434092at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009922">
        <property type="term" value="F:fatty acid elongase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034625">
        <property type="term" value="P:fatty acid elongation, monounsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034626">
        <property type="term" value="P:fatty acid elongation, polyunsaturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019367">
        <property type="term" value="P:fatty acid elongation, saturated fatty acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002076">
        <property type="entry name" value="ELO_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157:SF126">
        <property type="entry name" value="ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11157">
        <property type="entry name" value="FATTY ACID ACYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01151">
        <property type="entry name" value="ELO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="11" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="33"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="139"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="238"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG93639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="294" mass="35660" checksum="8DE821FB61FCAEC6" modified="2017-02-15" version="1">MFLNSVFLNDIGEKILKFFNPQLKYENRITKKWFLMSPSHFFIVFFSYFIFIIVAYLHKLKYNTKRKQIFDKQTNKNKNASIPSKKDNSYFQNFLSKIIPIYNLIQVFCSFYITLFTLYEAKNRNFSLVYNPSDYTQDSIAFYSWLFYINKMCDFFDTILIVLRSKWNQFTFLHVYHHLSVFFIMWVNTSVGYDGDIYYVISINSFVHFIMYFYYFFTSLKIKVPIYLKTTVTYIQMIQFLSILLPCLFVLFFNFICEYPIRLVALSFCYCISLLILFINFSIQTYIFQKNKID</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQT2</accession>
    <name>A0A1J1GQT2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Protein serine/threonine kinase-1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CLK1</name>
        <name evidence="8" type="ORF">PGAL8A_00204600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527465.1">
        <property type="nucleotide sequence ID" value="XM_028670742.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQT2"/>
    <dbReference type="GeneID" id="39730573"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00204600"/>
    <dbReference type="OMA" id="MCLVFEP"/>
    <dbReference type="OrthoDB" id="283111at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14134">
        <property type="entry name" value="PKc_CLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051175">
        <property type="entry name" value="CLK_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE DOA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45646:SF11">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE DOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="391"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="277"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="319"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="340"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="723" mass="87073" checksum="DB54ED60E5C158BC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR28</accession>
    <name>A0A1J1GR28_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">MFS-type transporter, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00214300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527561.1">
        <property type="nucleotide sequence ID" value="XM_028670849.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR28"/>
    <dbReference type="GeneID" id="39730670"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00214300"/>
    <dbReference type="OMA" id="CAYPFIM"/>
    <dbReference type="OrthoDB" id="422206at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049680">
        <property type="entry name" value="FLVCR1-2_SLC49-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10924">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10924:SF6">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 49 MEMBER A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="301"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="332"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="387"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="415"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG94746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="610" mass="70582" checksum="C715C86DC14E83B1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR42</accession>
    <name>A0A1J1GR42_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Mitochondrial ribosomal protein L28, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00215900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527577.1">
        <property type="nucleotide sequence ID" value="XM_028670868.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR42"/>
    <dbReference type="GeneID" id="39730686"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00215900"/>
    <dbReference type="OMA" id="KAYTDHH"/>
    <dbReference type="OrthoDB" id="361870at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.40">
        <property type="entry name" value="Ribosomal protein L28/L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026569">
        <property type="entry name" value="Ribosomal_bL28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="Ribosomal_bL28/bL31-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037147">
        <property type="entry name" value="Ribosomal_bL28_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13528">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L28, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13528:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL28M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="L28p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="281" mass="33270" checksum="96242572F7BF6456" modified="2017-02-15" version="1">MPKNLNLFGKYLRRLGKSHKKGFKKKQIIHPIPVKAYGRVPSAASQTGLYHDEDFNYYTKVSYSLKKTRIKLKPNVFKKHIVSNILNTIIPNVRITTSALHAIDDAGGFDNYILRTSPEELRSNFGEKLRNVMYFYMSHPNIRSLSLPWKTFMNKSQQCDYYYAIYQHLRKKRLNELYKKKESGKYSPYYLPNDKNLHPQRQPFSLNTEINHLNLWYNNNKLLKKAFIEKLKEAKSFDQAYTDHHFLDSYKKGRGRGGGGKHGRTPRKRSKTYKYFEIRPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR49</accession>
    <name>A0A1J1GR49_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Vesicle transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00233800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the SFT2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527754.1">
        <property type="nucleotide sequence ID" value="XM_028671063.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR49"/>
    <dbReference type="GeneID" id="39730865"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00233800"/>
    <dbReference type="OrthoDB" id="10608565at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007305">
        <property type="entry name" value="Vesicle_transpt_Got1/SFT2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011691">
        <property type="entry name" value="Vesicle_transpt_SFT2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23137:SF6">
        <property type="entry name" value="VESICLE TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23137">
        <property type="entry name" value="VESICLE TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04178">
        <property type="entry name" value="Got1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="34"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="164" mass="19489" checksum="104A852D294D8FEB" modified="2017-02-15" version="1">MHEYLLREHYNLNENNRENNIFENILTLSLFERIAIFIIFFLLGILFLFLSLGAIPLIIIGNVKLFAFRYSMGNIFLLFSFSSLLTPYQRSQNRNEEFYLNQKALFISYFVCIILNILSCLYFHSSLLIIVFIILQFFISILYIINRFPWIRNVLSFTTVPITT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR76</accession>
    <name>A0A1J1GR76_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00243700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527852.1">
        <property type="nucleotide sequence ID" value="XM_028671173.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR76"/>
    <dbReference type="GeneID" id="39730965"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00243700"/>
    <dbReference type="OMA" id="DNTPNDY"/>
    <dbReference type="OrthoDB" id="378706at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="123"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="348"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="665" mass="80556" checksum="49E97EFB3FC1F28D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR84</accession>
    <name>A0A1J1GR84_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ribose-phosphate diphosphokinase</fullName>
            <ecNumber evidence="4">2.7.6.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PGAL8A_00237000</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>D-ribose 5-phosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15609"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.6.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ribose-phosphate pyrophosphokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.1" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527786.1">
        <property type="nucleotide sequence ID" value="XM_028671101.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR84"/>
    <dbReference type="GeneID" id="39730898"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00237000"/>
    <dbReference type="OMA" id="YFGWARQ"/>
    <dbReference type="OrthoDB" id="413572at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002189">
        <property type="term" value="C:ribose phosphate diphosphokinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006015">
        <property type="term" value="P:5-phosphoribose 1-diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000037">
        <property type="entry name" value="Phosphoribosylpyrophosphate synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000001">
        <property type="entry name" value="Ribose-phosphate pyrophosphokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002320">
        <property type="entry name" value="PRK01259.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210:SF32">
        <property type="entry name" value="RIBOSE-PHOSPHATE PYROPHOSPHOKINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14572">
        <property type="entry name" value="Pribosyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01400">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribose-phosphate pyrophosphokinase N-terminal" evidence="13">
        <location>
            <begin position="107"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF13793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG94973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="425" mass="47861" checksum="134386A8D2F07524" modified="2017-02-15" version="1">MNSLLFKKCRINFFKKNKFFNKENYGIKLTLLVSSGIGCYFLSNEANRKKFRQCCKDVKKNINELLYDKRSILIENTAFCDNANNHYHPLWRSEEKRPFEKKMENAILFSGTSNPVLSQNIADHLGTILGKVNLKRFADGEVSMQFLDSIRGKDVYIIQPTCPPVNENLIELLLMISTCRRASAKKITAVIPYYGYARQDRKLSSRVPISAADVARMIEAMGVDRVVAIDLHSGQIQGFFGPRVPVDNLEAQLIGLDYFTKKDLYKPVIVSPDAGGVYRARKFQDGLNHRGISDCGIAMLIKQRTKPNEIEKMDLVGNVYDSDVIIVDDMIDTSGTLCEAAKQLKKHGARRVFAFATHGLFSGPAIERIENSPLEEVVVTDTVKSNKNIDSCKKITKLSVSVLVADAIRRIHQKESLNDLFNIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRB2</accession>
    <name>A0A1J1GRB2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Apurinic/apyrimidinic endonuclease Apn1, putative</fullName>
            <ecNumber evidence="14">4.2.99.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">APN1</name>
        <name evidence="14" type="ORF">PGAL8A_00244800</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Plays a role in mitochondrial DNA base excision repair (BER) pathway induced by oxidative stress. Has apurinic/apyrimidinic (AP) endonuclease activity towards double-stranded DNA (dsDNA) with a preference for C as opposite base. Has 3'-phosphatase activity; removes 3'-phosphate from blunt-end, recessed, and gapped DNA templates and thus, removes 3'-blocks for DNA polymerase activity during BER. Lacks 3'-5' exonuclease activity and does not cleave damaged bases by nucleotide incision repair (NIR).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the AP endonuclease 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.18" evidence="14"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527862.1">
        <property type="nucleotide sequence ID" value="XM_028671184.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRB2"/>
    <dbReference type="GeneID" id="39730976"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00244800"/>
    <dbReference type="OrthoDB" id="7663182at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00019">
        <property type="entry name" value="AP2Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.150:FF:000001">
        <property type="entry name" value="Probable endonuclease 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.150">
        <property type="entry name" value="Divalent-metal-dependent TIM barrel enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00152">
        <property type="entry name" value="Nfo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001719">
        <property type="entry name" value="AP_endonuc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018246">
        <property type="entry name" value="AP_endonuc_F2_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00587">
        <property type="entry name" value="nfo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002199">
        <property type="entry name" value="PRK01060.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21445:SF0">
        <property type="entry name" value="APURINIC-APYRIMIDINIC ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21445">
        <property type="entry name" value="ENDONUCLEASE IV ENDODEOXYRIBONUCLEASE IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00518">
        <property type="entry name" value="AP2Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="Xylose isomerase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00729">
        <property type="entry name" value="AP_NUCLEASE_F2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00730">
        <property type="entry name" value="AP_NUCLEASE_F2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00731">
        <property type="entry name" value="AP_NUCLEASE_F2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51432">
        <property type="entry name" value="AP_NUCLEASE_F2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="14" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="14" id="KW-0540">Nuclease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Xylose isomerase-like TIM barrel" evidence="13">
        <location>
            <begin position="229"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00054483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG95049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="485" mass="56661" checksum="B51084B28E285BCA" modified="2017-02-15" version="1">MVFKLFIYFFLYMIRINLFKHNLYALSYKIINKYKYSNINKCIHLEKTPFEKYYSINYKNIRNNKIIEKKEEKFFSRNFYLKTPKEIDIDKKLRETSMEEKNKSDEKNNTKLKKEVSEHVNDMNVINTKKENVEEIKKTVKTEKNNVSEKVVTKKKIDKKGIKKKKLEISTSKVSYPPIPSSLEKKWDDFKKIKEYAKKTNVYLGAHISASGGVQNAPVNSFNISGLSFALFLKNQRKWESASLTSDNINKFEENCKKYEYDKNFILPHGSYLINLANPDKEKREKSYLSFLDDIKRCEQLKIKMYNFHPGSTVGLCSIQEGIKNISDCINRVHKETSDVIIVLENSAGQKNSIGSKFEHLRDIINQVNDKSRIGVCLDTCHTLAAGYDIKSFENFEKVMKQFDEIVNTKYLKAVHLNDSKSDIGSGLDRHENIGKGKLTIDTFKYIMTSDYFKNMPIILETPDVTNDESVYKYEIEYLYKLCLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSG3</accession>
    <name>A0A1J1GSG3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00261900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528027.1">
        <property type="nucleotide sequence ID" value="XM_028671368.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSG3"/>
    <dbReference type="GeneID" id="39731148"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00261900"/>
    <dbReference type="OMA" id="IMCQKME"/>
    <dbReference type="OrthoDB" id="370926at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="22"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="243" mass="29050" checksum="F631C023CFC93C2C" modified="2017-02-15" version="1">MEDFLTKLKIISEQYNNLLLEKKIIDKRIASIEENITKYEETKQKSIKEVEFKKNQLLKNKNKHLIKCQKMEQLNNRLNEILIRKQSIDDEEEKKIIKKQIDMVSNTYVLLKNIQKLNDVIIKNNEYYKVITDKIHNNGFNNKKTLNILNCFLNKSRANIQDKDYDNSTNNLKIIPTNEITKNLIYLFSENHTTLILEKQQFLFVLLMNILKKILESKKDTYDENTSNEVIHNFLYQNYISLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSH6</accession>
    <name>A0A1J1GSH6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">26S proteasome regulatory subunit RPN1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RPN1</name>
        <name evidence="8" type="ORF">PGAL8A_00018400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit S2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528226.1">
        <property type="nucleotide sequence ID" value="XM_028671589.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSH6"/>
    <dbReference type="GeneID" id="39728706"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00018400"/>
    <dbReference type="OMA" id="LNYRMIG"/>
    <dbReference type="OrthoDB" id="10252509at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034515">
        <property type="term" value="C:proteasome storage granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042176">
        <property type="term" value="P:regulation of protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016643">
        <property type="entry name" value="26S_Psome_Rpn1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002015">
        <property type="entry name" value="Proteasome/cyclosome_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041433">
        <property type="entry name" value="RPN1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040892">
        <property type="entry name" value="RPN1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10943">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10943:SF1">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01851">
        <property type="entry name" value="PC_rep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18051">
        <property type="entry name" value="RPN1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17781">
        <property type="entry name" value="RPN1_RPN2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015965">
        <property type="entry name" value="26S_Psome_Rpn1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 8" id="KW-0647">Proteasome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="RPN1 N-terminal" evidence="6">
        <location>
            <begin position="46"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="26S proteasome non-ATPase regulatory subunit RPN1 C-terminal" evidence="7">
        <location>
            <begin position="879"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="623"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="18"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="623"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="639"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF18051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="938" mass="105338" checksum="D5AE6183AD450D6A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSI1</accession>
    <name>A0A1J1GSI1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00021100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528252.1">
        <property type="nucleotide sequence ID" value="XM_028671617.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSI1"/>
    <dbReference type="GeneID" id="39728733"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00021100"/>
    <dbReference type="OMA" id="YVTRPLY"/>
    <dbReference type="OrthoDB" id="372835at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="288"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="317"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="496" mass="58875" checksum="06064CE7B20F03B3" modified="2017-02-15" version="1">MNKIKTKNSVHKMEYCDTYISSYVDWVRDIFNSDVLLNVNFLNIENEKKEKKKRKLNQVEKIIKKSKIINEENSPNNVLIEETNNKDENNCYLKNTNFNESYKSTNFNIIESNNNKHNLNENYFINNNFNMINSSKKNSSSCDISEIDSEEDSYKETIEKNNNVDHSNIFNDNFKNLSEICNNLNKITPNKLNRDIILNENSNKIYNHRLNIIGDEVSNFLIYTSDKDDINNDNEEEIKSNNSIFISFNYDQFKKNVHLIEEIDKEFYSISKEEEKKQERKKEKSGKIVNNNSNNVSNNISFNNYIDDNINYNINANNNNNNNNNYNNDDDDDVDDNNNNNDDVDDNNNNNDYDDVDDNNNENKNEYNNNNNNNDDVDDNNNNNNDDDDDNNNPINFKKNEKIIKEENFSSNNNFLNNFCFWNIESDSYISRPLYVQNNNKKYFTFLEESEEMIKNYSSNQYSIKFVPRHLLYVLSQVASRIFFDPMYRKQLFFQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSL7</accession>
    <name>A0A1J1GSL7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PIR-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00268500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000038">
        <property type="protein sequence ID" value="CRG95483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528292.1">
        <property type="nucleotide sequence ID" value="XM_028671662.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSL7"/>
    <dbReference type="GeneID" id="39731215"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00268500"/>
    <dbReference type="OMA" id="FIMESQI"/>
    <dbReference type="OrthoDB" id="394175at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="306"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="347"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="401" mass="45237" checksum="EA1E2E89674D53FA" modified="2017-02-15" version="1">MKTHHHSMMILCLFILVWIFQYFFNMSFEIKENNLKKVSQLRIGRLLAEAQSCPLTTETGYICRSGENLTTWLESLQGDLLTQIEKNQNNFTCNNTDSLINWMSNKTMEMAFSLNRNSDIKEKGILNNAWGIWNNLIECVKDYFSYIVDKFSCKITSDNISNITDWMYNRSRLVIRELNLDSDIGGKKVLNDTLSVWRQITKSVTNFIMESQINSTMSIDPTKNSSDLLSTPVLPTTSDSLSTSSSLITGTSSNISSNISLNDSINGIKTTPILEIITTTLGDINTSPGNDGSTTTACSGFFCGSIASISISVPLVVIGGVLFLTLLYKYTRIGSLLGRGNLQKEKGRKRLRETSLDNIEDPSESSMEKEEMKPKRSRLNSFLRAFGYKYRNIFPYIDENR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSS7</accession>
    <name>A0A1J1GSS7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00010100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528145.1">
        <property type="nucleotide sequence ID" value="XM_028671498.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSS7"/>
    <dbReference type="GeneID" id="39728623"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00010100"/>
    <dbReference type="OMA" id="LYNNFFM"/>
    <dbReference type="OrthoDB" id="382158at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="109" mass="12847" checksum="1EDB3E0BAFDD8B7A" modified="2017-02-15" version="1">MSMFLNILIFIDAACVAFLSILFLMINLNEESLLLSKKHRENGKKALVAAIFLYAIFLLLLFTYKSYKNKRKLYNNFFVKKRNTPKYVQLTSTYLSGSDEYEHYELNKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSY6</accession>
    <name>A0A1J1GSY6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00016700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528209.1">
        <property type="nucleotide sequence ID" value="XM_028671570.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728689"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00016700"/>
    <dbReference type="OMA" id="HILYAHF"/>
    <dbReference type="OrthoDB" id="392791at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1405"/>
            <end position="1424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="413"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="828"/>
            <end position="898"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1547" mass="186339" checksum="22CF93BA04165275" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT75</accession>
    <name>A0A1J1GT75_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HRDC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00288700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528498.1">
        <property type="nucleotide sequence ID" value="XM_028671891.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT75"/>
    <dbReference type="GeneID" id="39731420"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00288700"/>
    <dbReference type="OrthoDB" id="382111at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.80">
        <property type="entry name" value="HRDC domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002121">
        <property type="entry name" value="HRDC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044876">
        <property type="entry name" value="HRDC_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00570">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="HRDC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50967">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HRDC" evidence="1">
        <location>
            <begin position="173"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="250" mass="29160" checksum="67A888FAF9A61805" modified="2017-02-15" version="1">MKKVNVINNFDEQIKSLNDNNIPYKYYNPSHNINIRNYLSSNDIKYKCKPNSYLSLNELVEFVDNLNNSKNDNINYIINDYDNSNIEIIDGKVNSNEKYIKENSENYEGFNNKNLINENNTLKLVNDTYNCHTNYTKNSNVIYTLSNEISNSSENKNIIHNKINIQTSSISNINNDNNLLKDLLKCRSTLSKKNNIKDPEKLISTKNLKLMLLHRPKSIDDIRNLNLTGFGEDKIKKYGYDFLKVFLSNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT81</accession>
    <name>A0A1J1GT81_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Protein phosphatase inhibitor 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">I2</name>
        <name evidence="1" type="ORF">PGAL8A_00396300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527080.1">
        <property type="nucleotide sequence ID" value="XM_028670316.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT81"/>
    <dbReference type="GeneID" id="39732493"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00396300"/>
    <dbReference type="OMA" id="HYDEYKT"/>
    <dbReference type="OrthoDB" id="551302at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004864">
        <property type="term" value="F:protein phosphatase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009966">
        <property type="term" value="P:regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007062">
        <property type="entry name" value="PPI-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12398:SF20">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY INHIBITOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12398">
        <property type="entry name" value="PROTEIN PHOSPHATASE INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04979">
        <property type="entry name" value="IPP-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0650">Protein phosphatase inhibitor</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="143" mass="16581" checksum="E9A0FA9A3F5055B3" modified="2017-02-15" version="1">MKKKIDKSSTKKTISWDEVTINEQDKERGSRMKILEPNTPFNFILMDSASEDEASKYGDIKGNNEGMNNIADDLISKLNQLVEKQESKSSSNIDFKEKRKKHYNEYKMLQELRKSGTFDDIDECALDENDSNYDNNKIPKSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTA4</accession>
    <name>A0A1J1GTA4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-f protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00272800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000043">
        <property type="protein sequence ID" value="CRG95528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528337.1">
        <property type="nucleotide sequence ID" value="XM_028671712.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTA4"/>
    <dbReference type="GeneID" id="39731260"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00272800"/>
    <dbReference type="OrthoDB" id="384111at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="566" mass="67035" checksum="A42C8FE3350E5FF1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTM2</accession>
    <name>A0A1J1GTM2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HID1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00304600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528642.1">
        <property type="nucleotide sequence ID" value="XM_028672050.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTM2"/>
    <dbReference type="GeneID" id="39731579"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00304600"/>
    <dbReference type="OrthoDB" id="432953at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005797">
        <property type="term" value="C:Golgi medial cisterna"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000138">
        <property type="term" value="C:Golgi trans cisterna"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026705">
        <property type="entry name" value="Hid-1/Ecm30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21575">
        <property type="entry name" value="PROTEIN HID1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21575:SF12">
        <property type="entry name" value="PROTEIN HID1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09742">
        <property type="entry name" value="Dymeclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="326"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="370"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="707"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="421"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="524"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="993" mass="119542" checksum="40D486D2EAF56D73" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTP0</accession>
    <name>A0A1J1GTP0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Inner membrane complex protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00206700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527485.1">
        <property type="nucleotide sequence ID" value="XM_028670765.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTP0"/>
    <dbReference type="GeneID" id="39730594"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00206700"/>
    <dbReference type="OMA" id="CCCEKEE"/>
    <dbReference type="OrthoDB" id="375323at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="142" mass="16482" checksum="5141422683637778" modified="2017-02-15" version="1">MNLFKKSTCSICNACKCCCGEIKITERTYTYNELDDLYKNTNTVSFPCIPTERIILNSFDNPELYYHQIDSEFYAKNILKDVPLISYAQGPFFERMNEIRTNKKYHLPTTSYVSDPIYIRRKEKCSISGLSSSICCEGCRCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTR0</accession>
    <name>A0A1J1GTR0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00209100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527509.1">
        <property type="nucleotide sequence ID" value="XM_028670792.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTR0"/>
    <dbReference type="GeneID" id="39730618"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00209100"/>
    <dbReference type="OMA" id="NIFVPNC"/>
    <dbReference type="OrthoDB" id="360261at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="304" mass="36047" checksum="41550F07D613DAE4" modified="2017-02-15" version="1">MDENLYDKFDASLHTNKNNDNEKNISYEDSNSTDYSICSELLNNCDKNKKRKISAFKNFKNDNDIKIGVKIALQLLLNNQPFPVKREDLFSTINIYVPNCNNNFKKKIILKLLKKQVNDILALKLLTLSSKTKNEYVLSQNILYEPHNDFLLSNLDHNIRGFLIFLIPFFKVFHNKIPLNYLLFELENVGHKTLKTKEEIIKNLTTPSLFTNIKNNILMNEIIEPLDYIIYAKKLSYIDFYNDQYDENSLDGFYCTPTIRYEYEINMKNYIKELLKIPNKKYHLKDMYALFEEKYFLDVNCDNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU26</accession>
    <name>A0A1J1GU26_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome c oxidase assembly protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00319900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the COX19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528794.1">
        <property type="nucleotide sequence ID" value="XM_028672220.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU26"/>
    <dbReference type="GeneID" id="39731732"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00319900"/>
    <dbReference type="OMA" id="HVSCREY"/>
    <dbReference type="OrthoDB" id="268594at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051383">
        <property type="entry name" value="COX19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21107">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21107:SF2">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="141"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="210" mass="24888" checksum="97E1C551476A677C" modified="2017-02-15" version="1">MDKKRSLVKKPDRGSFLLDHNNECTSIKNKYLKCLKENYNDHVSCREYSKQYFTCRMDNNLLEKQSLNNLGFSENEVNHESRIKNFKDVYSYNTYNEKMEELSMNKLNNKNNTPIIETFPSKEVKQNNNKNSVDTKKVKKKEFLLLNINNKNEREKNLNSESAEKIEEKKITIKRKEADGYLAGKEYIKALSKKKKKSFFLNNIFKNNNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU30</accession>
    <name>A0A1J1GU30_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00323300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000050">
        <property type="protein sequence ID" value="CRG96020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528828.1">
        <property type="nucleotide sequence ID" value="XM_028672258.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731766"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00323300"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="762"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="378"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="495"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="732"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1140"/>
            <end position="1227"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1318"/>
            <end position="1345"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1561"/>
            <end position="1592"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1681"/>
            <end position="1712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="378"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="396"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="495"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="550"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="573"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="732"/>
            <end position="744"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2070" mass="244076" checksum="D84DEEF5F7B51805" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU46</accession>
    <name>A0A1J1GU46_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00324900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000052">
        <property type="protein sequence ID" value="CRG96036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528844.1">
        <property type="nucleotide sequence ID" value="XM_028672275.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU46"/>
    <dbReference type="GeneID" id="39731782"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00324900"/>
    <dbReference type="OMA" id="NVHENIC"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="299"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="337" mass="39780" checksum="F114070E3E7E7920" modified="2017-02-15" version="1">MALLYNEGCPNSEEDFTKCNVIACMIRGGRFKTHHCDLAFVAINVKYPSSDIPNNLAKNIFTYDHYIPRDGKQSIVTFLSNDENEIVFLYEIYPYNDRHLFEPFLCRLRDKNQKLIFCEKINRDYVGRTLSFNSIDIIDKKGRENYRIRLKNLMNTRHVSRILDYNDIFFSRDACHYIKEANVHENICRYSICTKDKNDYTSCVDAKFTGKLFHIQKHSKPYEGKEKFIYLPNICLNQGLKINCTPYLCEYERPLELTPCKKLDISIVKNIIPYSERSIVKQTRTTNLDYDNNLNMSSLVAMTFIPFLIIFFFIGCYIYKTIMKNKSKKIKMRSKEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUF6</accession>
    <name>A0A1J1GUF6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Rubredoxin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00308700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528683.1">
        <property type="nucleotide sequence ID" value="XM_028672096.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUF6"/>
    <dbReference type="GeneID" id="39731620"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00308700"/>
    <dbReference type="OMA" id="PNCGQSN"/>
    <dbReference type="OrthoDB" id="368964at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57802">
        <property type="entry name" value="Rubredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="163" mass="19409" checksum="FF92B5096433B3E0" modified="2017-02-15" version="1">MRLYLLIFIYIVTCVTVFSIKIQRNIHYINNKILNNIQKKNKTLKKHFNLNSHNDQTYLHKIQSNITNVGKNFSKRINFFKISVIIFTFSSLIAGLFYKKREKEKNENVDNSKNCEKEFFKYKCVKCNLVIFPAKGREKKFLKDNFICPNCGESNMDKYLTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUQ0</accession>
    <name>A0A1J1GUQ0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="5">PPIase</shortName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00342300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529010.1">
        <property type="nucleotide sequence ID" value="XM_028672460.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUQ0"/>
    <dbReference type="GeneID" id="39731953"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00342300"/>
    <dbReference type="OMA" id="ENHEITH"/>
    <dbReference type="OrthoDB" id="193499at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000019">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011822406" description="Peptidyl-prolyl cis-trans isomerase" evidence="5">
        <location>
            <begin position="21"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="6">
        <location>
            <begin position="31"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="192" mass="21359" checksum="FE9B05745FC6A1BE" modified="2017-02-15" version="1">MRKLLSVILIIFFVTQNYFANETHEITHRAYFDISVDNKPIGRIIFGLYGKIAPKTVENFISICKGTVVNGKMLNYTNSIFHRIIPNFMAQGGDITNFNGTGGLSIYGNKFDDENFIAKHNKRGILSMANAGKNTNGSQFFIIFVRTPWLDGKHVVFGEVIEGLDKLIHIEAVGSDSGEPSKRVLVTESGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUT0</accession>
    <name>A0A1J1GUT0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="8">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00219800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the peptidase C12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527616.1">
        <property type="nucleotide sequence ID" value="XM_028670911.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUT0"/>
    <dbReference type="GeneID" id="39730725"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00219800"/>
    <dbReference type="OMA" id="IDLHYVC"/>
    <dbReference type="OrthoDB" id="427186at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.532.10:FF:000006">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.532.10">
        <property type="entry name" value="Peptidase C12, ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001578">
        <property type="entry name" value="Peptidase_C12_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036959">
        <property type="entry name" value="Peptidase_C12_UCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589:SF17">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01088">
        <property type="entry name" value="Peptidase_C12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00707">
        <property type="entry name" value="UBCTHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52048">
        <property type="entry name" value="UCH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7 8" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4 7 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UCH catalytic" evidence="9">
        <location>
            <begin position="6"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <feature type="site" description="Important for enzyme activity" evidence="7">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG94801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="226" mass="26079" checksum="E5FDD6A06C1B69EA" modified="2017-02-15" version="1">MLKKNIWIPIESNPDSMFLYSCKLGQSKLKFLDIYGFHKELLDMIPKPVHAIIFLYPLSEKLNGNNSNDGYIKKNIDNIWFIKQNIRNSCGTIALLHLHNNLKNKFLLDRGSIADNFFNKVKDMTPDERAKEFENTKSFELLHHEFAGEDLGTEEIVDVDTHFIVFIEIDGHVVELDGRKNEPIIHCLTTPDNFLYDAANIIKKNFIDKCFDDNRFSALAVVSNTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUV1</accession>
    <name>A0A1J1GUV1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Histone acetyltransferase</fullName>
            <ecNumber evidence="3 12">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">MYST</name>
        <name evidence="14" type="ORF">PGAL8A_00345200</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-lysyl-[protein] + acetyl-CoA = N(6)-acetyl-L-lysyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:45948"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10731"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="2.3.1.48"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the MYST (SAS/MOZ) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="3 12"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529039.1">
        <property type="nucleotide sequence ID" value="XM_028672492.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUV1"/>
    <dbReference type="GeneID" id="39731982"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00345200"/>
    <dbReference type="OMA" id="DYYVHFL"/>
    <dbReference type="OrthoDB" id="787137at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000476">
        <property type="entry name" value="Histone acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.60:FF:000001">
        <property type="entry name" value="Histone acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000053">
        <property type="entry name" value="Histone acetyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.60">
        <property type="entry name" value="N-acetyl transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002717">
        <property type="entry name" value="HAT_MYST-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050603">
        <property type="entry name" value="MYST_HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025995">
        <property type="entry name" value="Tudor-knot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040706">
        <property type="entry name" value="Zf-MYST"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10615">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10615:SF161">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE KAT7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01853">
        <property type="entry name" value="MOZ_SAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11717">
        <property type="entry name" value="Tudor-knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17772">
        <property type="entry name" value="zf-MYST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51726">
        <property type="entry name" value="MYST_HAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0007">Acetylation</keyword>
    <keyword evidence="8" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYST-type HAT" evidence="13">
        <location>
            <begin position="215"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="11">
        <location>
            <position position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR602717-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG96234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="493" mass="58127" checksum="B6ADA2E13F4FDA34" modified="2017-02-15" version="1">MGGSKNDNLYVMKGGGISKCAKGNKANGESNNKIFGKNLASSKNKEKINVNKNSKGSNNKIRTAGKVINTISKFNDSYALIFPNALPVKQILWGLDPLNKVWRYCSIVYARPKNKNLNDINLIFPLNINKSEIINKINNELNNNNNTLKESDYDYYVHWEKFDRRLDCWLPYENLRLLDKEPDDGLPLIKDTESVSDHEHAGIDKEYLREHEENTKLKTINQIKFGKYLIDTWYFSPYPKEYQNIDVLYICEFCLSFYKEEKEMIRHTEKCEIRHPPGNEIYRNDKISIFEIDGNYFRIYCENLCFLSKLFLDHKTLKHRVNLFLFYVITEYDEYGYHITGYFSKEKYSKNNVSCILTLPQHQKKGYGKFLINFSYFLSQTEKRTGTPERPLSDLGVASYMAYWYETLLKVLVNYEQLSIHELSEITSIETNDIISCLEEKEILKNISNGEYFYYINPKQLEFILSKINQKNSELCRNKLHWVSYDYYLALYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVF9</accession>
    <name>A0A1J1GVF9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00373600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529316.1">
        <property type="nucleotide sequence ID" value="XM_028672800.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVF9"/>
    <dbReference type="GeneID" id="39732266"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00373600"/>
    <dbReference type="OMA" id="ECINNWW"/>
    <dbReference type="OrthoDB" id="361772at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012859628" description="PH domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="172" mass="20188" checksum="87B38DD5CB69AC0C" modified="2017-02-15" version="1">MNFLIFFLSIFLILTHSFYLSQNDLNLCKSTYRGILKYHQKKDKNEFFNVSAVLKNNTLELYRGSKFFESIDLREVITPLIIFSTNSECLTINIISKDSIVLCCNTEECINNWWFFLTKQILCLNQGEMRHEDDNKTIEDDQYKNINNFDGISINIQEDLDDIPNVSIKTES</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVM7</accession>
    <name>A0A1J1GVM7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Formin 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00359600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529177.1">
        <property type="nucleotide sequence ID" value="XM_028672646.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVM7"/>
    <dbReference type="GeneID" id="39732126"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00359600"/>
    <dbReference type="OrthoDB" id="1668162at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2220">
        <property type="entry name" value="Formin, FH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015425">
        <property type="entry name" value="FH2_Formin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042201">
        <property type="entry name" value="FH2_Formin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051144">
        <property type="entry name" value="Formin_homology_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45733">
        <property type="entry name" value="FORMIN-J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45733:SF31">
        <property type="entry name" value="GENOME ASSEMBLY, CHROMOSOME: II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02181">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00498">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101447">
        <property type="entry name" value="Formin homology 2 domain (FH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51444">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FH2" evidence="1">
        <location>
            <begin position="245"/>
            <end position="662"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="682" mass="80989" checksum="03BC64B3CE67B4FB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVY2</accession>
    <name>A0A1J1GVY2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleoporin NUP100/NSP100, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">NUP100</name>
        <name evidence="2" type="ORF">PGAL8A_00417600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529399.1">
        <property type="nucleotide sequence ID" value="XM_028672892.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732707"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00417600"/>
    <dbReference type="OMA" id="NDIQKTT"/>
    <dbReference type="OrthoDB" id="2538017at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025574">
        <property type="entry name" value="Nucleoporin_FG_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13634">
        <property type="entry name" value="Nucleoporin_FG"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1043"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1075"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1132"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1424"/>
            <end position="1442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1855" mass="211121" checksum="2895431B1EF477F4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW03</accession>
    <name>A0A1J1GW03_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00372500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529305.1">
        <property type="nucleotide sequence ID" value="XM_028672787.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW03"/>
    <dbReference type="GeneID" id="39732255"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00372500"/>
    <dbReference type="OMA" id="SHTNICI"/>
    <dbReference type="OrthoDB" id="383593at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="868" mass="102216" checksum="EDDEFD34CCF8E213" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW16</accession>
    <name>A0A1J1GW16_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Regulator of chromosome condensation, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00432700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529550.1">
        <property type="nucleotide sequence ID" value="XM_028673059.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732859"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00432700"/>
    <dbReference type="OMA" id="HDQHGKH"/>
    <dbReference type="OrthoDB" id="10256179at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051625">
        <property type="entry name" value="Signaling_Regulatory_Domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22872">
        <property type="entry name" value="BTK-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22872:SF2">
        <property type="entry name" value="INHIBITOR OF BRUTON TYROSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00415">
        <property type="entry name" value="RCC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13540">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="280"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2735"/>
            <end position="2762"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="2166"/>
            <end position="2193"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="2362"/>
            <end position="2544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="2743"/>
            <end position="2754"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3043" mass="358383" checksum="127A382DACD3F445" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW71</accession>
    <name>A0A1J1GW71_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA-directed RNA polymerase subunit I, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00002600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528072.1">
        <property type="nucleotide sequence ID" value="XM_028671417.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW71"/>
    <dbReference type="GeneID" id="39728548"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00002600"/>
    <dbReference type="OMA" id="MDIYNDN"/>
    <dbReference type="OrthoDB" id="259769at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006360">
        <property type="term" value="P:transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.940.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020708">
        <property type="entry name" value="DNA-dir_RNA_polK_14-18kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006110">
        <property type="entry name" value="Pol_omega/Rpo6/RPB6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028363">
        <property type="entry name" value="RPB6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036161">
        <property type="entry name" value="RPB6/omega-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006111">
        <property type="entry name" value="Rpo6/Rpb6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47227">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE SUBUNIT K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47227:SF5">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01192">
        <property type="entry name" value="RNA_pol_Rpb6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500154">
        <property type="entry name" value="RPB6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000778">
        <property type="entry name" value="RpoK/RPB6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01409">
        <property type="entry name" value="RNA_pol_Rpb6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63562">
        <property type="entry name" value="RPB6/omega subunit-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01111">
        <property type="entry name" value="RNA_POL_K_14KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="10"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="151" mass="17425" checksum="B5B08E9454E93989" modified="2017-02-15" version="1">MDGFNDVYLNDDDEYMGDEFGQGVDSDDGDNYDNDIDIITDNQIKKDKSDYENSEGNDDSIRITSPYLTKYEKARIIGTRALQISLNAPLTIPIETQNDSNNKSEYDNYLNNDPLVIAEKELYNKSIPFILRRYLPNGSYEDWKLDELIID</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWD3</accession>
    <name>A0A1J1GWD3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00420900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529433.1">
        <property type="nucleotide sequence ID" value="XM_028672929.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732741"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00420900"/>
    <dbReference type="OrthoDB" id="45365at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="545"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="545"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1410" mass="170383" checksum="1355AD804E5CCF44" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWD7</accession>
    <name>A0A1J1GWD7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00443800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529660.1">
        <property type="nucleotide sequence ID" value="XM_028673181.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWD7"/>
    <dbReference type="GeneID" id="39732971"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00443800"/>
    <dbReference type="OMA" id="NKYYLDM"/>
    <dbReference type="OrthoDB" id="371390at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="414"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="126"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="485" mass="57863" checksum="34876C9DB3533130" modified="2017-02-15" version="1">MKSNQNNITDELLNEKKDVKLINESEENKYNLKSESHSSSEFEFNFKKNITDNFEVKNRGLFKLSLGNQTYLKSNPINENENEKKIYDPYKKKNLEYDNKNNGIIKPKFLEEDKTKNVDENKDKIISKLKKEIKLLTNKLKEKADKIENVQKDNFHLEQMYKNKYYIDIKKEKKKVIDIHSKNNELIRRLNYYSESFQQLKQKIRCLTRNVLSLIQCIDTTENLKFLCKNMNDISVILESTEYKSSEEDKYEPKENNEKLNIFNLKNVRNRNKKKENRDPTKKLYHSISSLHNNYKFTPNCKCTTKKKEKLGYILTNKKTDFLKSDSFLNCCKKINKQKKNLPNSPIKKKYSFEYYYNLKKPSNINSKKKNTLPNLSIHMKKISPETTENILNLFRKTRKINYLLRNSLNVENYKKDNSQKRNKSNGNYKKESVKRKASIEYTLKNNYYSIKRNSNLKKETLNNLLSKEIHNRSIIDKITKISKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWK9</accession>
    <name>A0A1J1GWK9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00016600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528208.1">
        <property type="nucleotide sequence ID" value="XM_028671569.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728688"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00016600"/>
    <dbReference type="OMA" id="YGCNYGC"/>
    <dbReference type="OrthoDB" id="10257284at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="503"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1962" mass="237854" checksum="318EDF344B5E6FB5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWR9</accession>
    <name>A0A1J1GWR9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00446500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529687.1">
        <property type="nucleotide sequence ID" value="XM_028673212.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWR9"/>
    <dbReference type="GeneID" id="39732998"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00446500"/>
    <dbReference type="OMA" id="MIFKRAN"/>
    <dbReference type="OrthoDB" id="372075at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="253" mass="29985" checksum="0D8A183F5E1420F0" modified="2017-02-15" version="1">MNKNKIVITLFKNIKCFKYLSISKSYFHILFTNENKGNKFLNFKNMTDFENKKIVLLDIESENRNIRKKINRTFIGSILLSSITICLIELNLIYNIYGYIVSVGLIIFFTIYLLFYNSLILRAVLDYENKNLLLYPFTLLKRNNLKKQIIISLHEIKKINKLKKYIQLHLKKEKSVSIFNFIPLHIPRYNCAKTSLPKENKKDILYSYDFNNLNISVFNQKRSKIDVPNIKKNIEGYPLNLIEENKLISLLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWS0</accession>
    <name>A0A1J1GWS0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00450000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000076">
        <property type="protein sequence ID" value="CRG96919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529722.1">
        <property type="nucleotide sequence ID" value="XM_028673250.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWS0"/>
    <dbReference type="GeneID" id="39733033"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00450000"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013380400" evidence="2">
        <location>
            <begin position="29"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="289" mass="34432" checksum="323F08BC9F441156" modified="2017-02-15" version="1">MKTLTLCLKITTFLLLILLYQCFYKCDSYKTLIDKNILQTKNKLKYERVLTEGNIEGKKQTYAEGCLEESPLDNKKNKCKNQDKYKDPSNYWNKVIIPQMWKRFDQETSGMDPKLKEKKWNVELHKFSNTKVRDMHLISRRCDFSDEEKKQKIDSIMRELHSEFEKFLCKYKKGMTDNKAESESKKGMTDNKTESESKKGMTDNKTESESKKELRDNKTECESNKEMRDKKTESESKKEMTDNKTECESNKEMKDNKTESESKRDQGKNKKKNEKSNIFKFLFCRFDNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWV7</accession>
    <name>A0A1J1GWV7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit</fullName>
            <shortName evidence="8">Oligosaccharyl transferase 48 kDa subunit</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00432400</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the oligosaccharyltransferase (OST) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endoplasmic reticulum membrane</location>
            <topology evidence="8">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the DDOST 48 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529547.1">
        <property type="nucleotide sequence ID" value="XM_028673056.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWV7"/>
    <dbReference type="GeneID" id="39732856"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00432400"/>
    <dbReference type="OMA" id="AQEIILW"/>
    <dbReference type="OrthoDB" id="29105at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018279">
        <property type="term" value="P:protein N-linked glycosylation via asparagine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005013">
        <property type="entry name" value="DDOST_48_kDa_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055459">
        <property type="entry name" value="OST48_MD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055457">
        <property type="entry name" value="OST48_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10830">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE 48 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10830:SF0">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE 48 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23358">
        <property type="entry name" value="OST48_MD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03345">
        <property type="entry name" value="OST48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011830819" description="Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit" evidence="8">
        <location>
            <begin position="23"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="429"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="OST48 N-terminal" evidence="9">
        <location>
            <begin position="53"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="OST48 middle" evidence="10">
        <location>
            <begin position="314"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF23358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG96743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="461" mass="55455" checksum="DAADF639626F56BF" modified="2017-02-15" version="1">MKIIIKIYFFLLFFVIKKKCICERKKLEIVDYNKKSIEGIIKNKIKKFHEKKLLLITNIINITETHRSFINLLNNEGNHIKNIINIHNATNSIIFDKKDSSIYDGLVIILDILNDEIVTKLKVSYLKLFIEKKKHIFFSLNSVVGKNSVHFLNELNISVHGNYSYVNDIFDNIFLKEDTNDEKLQKSFYTSEIIQNTPITNNKHKILFKGTAHSVLLKEKYYLKVLTCTKTCLLYGKNNNIIKKQKQGTELLLISSIQLENNFRLIFSSSSDIFSDFYFDLNEENKNFTYDLIQWNLKKIGVIRYNNFKIHKRTFKENSNFFIKDTIYISIDFYELRNNYWIPFKRDDIQYQLIKINVKSRNFLYNYKCIKNATYYKNIKLPGEHGIYKFQIYYLRKGYNILNLEYFLPVRNLLHYDKNKKVNFKNYPFYFYMYLSLLYFFLFTLILIFDDSDYNNKKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWY6</accession>
    <name>A0A1J1GWY6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sentrin-specific protease 1, putative</fullName>
            <ecNumber evidence="8">3.4.22.68</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SENP1</name>
        <name evidence="8" type="ORF">PGAL8A_00455500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.22.68" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529778.1">
        <property type="nucleotide sequence ID" value="XM_028673314.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWY6"/>
    <dbReference type="GeneID" id="39733088"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00455500"/>
    <dbReference type="OMA" id="NSKMESR"/>
    <dbReference type="OrthoDB" id="198735at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016926">
        <property type="term" value="P:protein desumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.395.10">
        <property type="entry name" value="Adenoviral Proteinase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46915:SF2">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46915">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEASE 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02902">
        <property type="entry name" value="Peptidase_C48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50600">
        <property type="entry name" value="ULP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="7">
        <location>
            <begin position="754"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="104"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="407"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="77"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="562"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="684"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="116"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="412"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="963" mass="115227" checksum="5F6502409CCDC3D4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX18</accession>
    <name>A0A1J1GX18_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">6-cysteine protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00276500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528376.1">
        <property type="nucleotide sequence ID" value="XM_028671756.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX18"/>
    <dbReference type="GeneID" id="39731297"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00276500"/>
    <dbReference type="OMA" id="IWVNKEY"/>
    <dbReference type="OrthoDB" id="368814at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012113932" description="6-cysteine protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="286" mass="32714" checksum="0545D90F228EA0A5" modified="2017-02-15" version="1">MFALISIILVIFHTKLIIGINNKNKICTCDFTDRLNFIPQQRTKILCDLKPKHGDEVKVIANENYEVSCFNNSTVYCPSKGYFLSNSIITKHSPKLKYSKTKMVLSGRNVSVYHLIIDENASDILFYCYVKPNQVSELLHGVVKIDLKREISEEYSKPLEDGTHVCDYSKGNLNIYPSSGFYYKNSRSVNCIYRVIPNKLFLIKLPKLDIVTESFLPSIVNCLSEHAFINFTLKHVEESEDSVTFHITFGEFTRSFNLSCSMDLSEYNIEPCAVGKKGNVTFFFNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX31</accession>
    <name>A0A1J1GX31_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CutA, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00470400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CutA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529926.1">
        <property type="nucleotide sequence ID" value="XM_028673478.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX31"/>
    <dbReference type="GeneID" id="39733237"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00470400"/>
    <dbReference type="OMA" id="NEFLMMI"/>
    <dbReference type="OrthoDB" id="2017693at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010038">
        <property type="term" value="P:response to metal ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004323">
        <property type="entry name" value="Ion_tolerance_CutA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23419">
        <property type="entry name" value="DIVALENT CATION TOLERANCE CUTA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23419:SF8">
        <property type="entry name" value="FI09726P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03091">
        <property type="entry name" value="CutA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="GlnB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011977967" evidence="2">
        <location>
            <begin position="17"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="176" mass="20482" checksum="85579505E5184E58" modified="2017-02-15" version="1">MLVITILIMFFPLLVTQKQRCNKLFFDSFFIKNFLRYNSLTKNTCYNKYYTFNNRKISTKMKGDSPFIAVYVTTPNKDVAENISNVLLKEKLASCVNIIPGIISLYHWKGEIAKDNEVLMMIKTKKHLFQEIVNSVKLNHPYEVPEVIAIPIQHGSEEYLKWVSNSVKPIDNQEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX57</accession>
    <name>A0A1J1GX57_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">WD repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00471800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529940.1">
        <property type="nucleotide sequence ID" value="XM_028673493.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX57"/>
    <dbReference type="GeneID" id="39733251"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00471800"/>
    <dbReference type="OMA" id="YAYNMIS"/>
    <dbReference type="OrthoDB" id="27537at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050505">
        <property type="entry name" value="WDR55/POC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44019:SF8">
        <property type="entry name" value="POC1 CENTRIOLAR PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44019">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="110"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="786" mass="93183" checksum="C2A704805B2127A0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX65</accession>
    <name>A0A1J1GX65_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00472600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529948.1">
        <property type="nucleotide sequence ID" value="XM_028673502.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX65"/>
    <dbReference type="GeneID" id="39733259"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00472600"/>
    <dbReference type="OrthoDB" id="378622at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="514" mass="60551" checksum="CAE6E265C3591F61" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXQ4</accession>
    <name>A0A1J1GXQ4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00465900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529881.1">
        <property type="nucleotide sequence ID" value="XM_028673428.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXQ4"/>
    <dbReference type="GeneID" id="39733192"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00465900"/>
    <dbReference type="OMA" id="YYNHLFL"/>
    <dbReference type="OrthoDB" id="370750at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="492"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1209" mass="146525" checksum="06AD278FB564BC5B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXU6</accession>
    <name>A0A1J1GXU6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00496500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530188.1">
        <property type="nucleotide sequence ID" value="XM_028673769.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXU6"/>
    <dbReference type="GeneID" id="39733498"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00496500"/>
    <dbReference type="OrthoDB" id="376432at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="193" mass="22890" checksum="0627C1C00DE81627" modified="2017-02-15" version="1">MRTFYVLSKSFFKCENYLINFLSKKNCMNINKKYFSEKSIINSIRKAKNKLDRGSLYLLQESINNDCKFLNEEKKVKFQKIINELNDLLNEKFYLIEEKTKILNQKNSNKYKNKEIFGLFVAGFFFAIGSVTHSIFYLASIYGFYILKKASTENNSKIYMETKLNNNKNKLIINKRNIDNLLNVLENDFLKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXU9</accession>
    <name>A0A1J1GXU9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C6H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00304400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528640.1">
        <property type="nucleotide sequence ID" value="XM_028672048.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXU9"/>
    <dbReference type="GeneID" id="39731577"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00304400"/>
    <dbReference type="OMA" id="TSHLFYD"/>
    <dbReference type="OrthoDB" id="3209743at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031615">
        <property type="entry name" value="Zfn-C6H2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15801">
        <property type="entry name" value="zf-C6H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52013">
        <property type="entry name" value="ZF_C6H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="236"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="C6H2-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="397"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="439"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="510"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="409"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="439"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="535"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS52013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="586" mass="69221" checksum="4F94A17C0E04E87D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXX3</accession>
    <name>A0A1J1GXX3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">glutamate synthase (NADH)</fullName>
            <ecNumber evidence="19">1.4.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">PGAL8A_00306800</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>2 L-glutamate + NAD(+) = L-glutamine + 2-oxoglutarate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13753"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="1.4.1.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid biosynthesis; L-glutamate biosynthesis via GLT pathway; L-glutamate from 2-oxoglutarate and L-glutamine (NAD(+) route): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Energy metabolism; nitrogen metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Nitrogen metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the glutamate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.14" evidence="19"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528664.1">
        <property type="nucleotide sequence ID" value="XM_028672074.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731601"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00306800"/>
    <dbReference type="OMA" id="APEAVMM"/>
    <dbReference type="OrthoDB" id="4327079at2759"/>
    <dbReference type="UniPathway" id="UPA00045"/>
    <dbReference type="UniPathway" id="UPA00634">
        <property type="reaction ID" value="UER00690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016040">
        <property type="term" value="F:glutamate synthase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
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    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016639">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097054">
        <property type="term" value="P:L-glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00982">
        <property type="entry name" value="gltB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00713">
        <property type="entry name" value="GltS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02808">
        <property type="entry name" value="GltS_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000017">
        <property type="entry name" value="Glutamate synthase [NADH], amyloplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1060.10:FF:000011">
        <property type="entry name" value="NAD(P)H-dependent glutamate synthase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.60:FF:000004">
        <property type="entry name" value="NAD(P)H-dependent glutamate synthase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="entry name" value="Alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.60">
        <property type="entry name" value="Glutamate synthase, alpha subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028261">
        <property type="entry name" value="DPD_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002489">
        <property type="entry name" value="Glu_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036485">
        <property type="entry name" value="Glu_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006982">
        <property type="entry name" value="Glu_synth_centr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002932">
        <property type="entry name" value="Glu_synthdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006005">
        <property type="entry name" value="Glut_synth_ssu1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051394">
        <property type="entry name" value="Glutamate_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01317">
        <property type="entry name" value="GOGAT_sm_gam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43100">
        <property type="entry name" value="GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43100:SF1">
        <property type="entry name" value="GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14691">
        <property type="entry name" value="Fer4_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00310">
        <property type="entry name" value="GATase_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04898">
        <property type="entry name" value="Glu_syn_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01645">
        <property type="entry name" value="Glu_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01493">
        <property type="entry name" value="GXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00419">
        <property type="entry name" value="ADXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69336">
        <property type="entry name" value="Alpha subunit of glutamate synthase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46548">
        <property type="entry name" value="alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="18" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0274">FAD</keyword>
    <keyword evidence="9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0288">FMN</keyword>
    <keyword evidence="17" id="KW-0314">Glutamate biosynthesis</keyword>
    <keyword evidence="13" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="15" id="KW-0408">Iron</keyword>
    <keyword evidence="16" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14 23" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="22">
        <location>
            <begin position="20"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="1540"/>
            <end position="1656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="2725"/>
            <end position="2775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="21">
        <location>
            <begin position="1552"/>
            <end position="1631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="21">
        <location>
            <begin position="1632"/>
            <end position="1648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="21">
        <location>
            <begin position="2725"/>
            <end position="2738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="21">
        <location>
            <begin position="2761"/>
            <end position="2775"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00009716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00024383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="CRG95856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2913" mass="332281" checksum="CA5B19122DF337B6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXX6</accession>
    <name>A0A1J1GXX6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GPI transamidase component PIG-S</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00469300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529915.1">
        <property type="nucleotide sequence ID" value="XM_028673465.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXX6"/>
    <dbReference type="GeneID" id="39733226"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00469300"/>
    <dbReference type="OMA" id="IATWDFY"/>
    <dbReference type="OrthoDB" id="371019at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="671"/>
            <end position="692"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="707" mass="84098" checksum="A719E2E95A6FD4C3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY89</accession>
    <name>A0A1J1GY89_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00485000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530073.1">
        <property type="nucleotide sequence ID" value="XM_028673640.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY89"/>
    <dbReference type="GeneID" id="39733383"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00485000"/>
    <dbReference type="OMA" id="WILIRFR"/>
    <dbReference type="OrthoDB" id="382086at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="188" mass="23057" checksum="84846DAD964E3B94" modified="2017-02-15" version="1">MFLQKYKITRKFPLNYIMLNNCKIFSRYIYTKNEINGIFNNVFKNILNDKTNTLQSIYNKYLYLNLNKVTKRFYNPRENINWILIRFRHRVSQLRKKKLKYKNHSKVALRFRLTKFGWERLQSGRNASKKNLSVKKYNEKMKIKYVSRDDIKKFKFQMPSYVLRIRDSPVDYNPNIMKARKFLPSHFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYC0</accession>
    <name>A0A1J1GYC0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Myb1-related transcription factor, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MYB1</name>
        <name evidence="6" type="ORF">PGAL8A_00512100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530349.1">
        <property type="nucleotide sequence ID" value="XM_028673947.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYC0"/>
    <dbReference type="GeneID" id="39733654"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00512100"/>
    <dbReference type="OMA" id="ECQKTWL"/>
    <dbReference type="OrthoDB" id="2143914at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019185">
        <property type="term" value="C:snRNA-activating protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001006">
        <property type="term" value="F:RNA polymerase III type 3 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042795">
        <property type="term" value="P:snRNA transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042796">
        <property type="term" value="P:snRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051575">
        <property type="entry name" value="Myb-like_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46621:SF1">
        <property type="entry name" value="SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Myb-like" evidence="5">
        <location>
            <begin position="271"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="414" mass="50353" checksum="617C66005E286A70" modified="2017-02-15" version="1">MNIENSEYKNLSSLEEKLHNYLTVIEKMIKLINGNIDKLNDYINKKYNEIKILSSKKPTRINWMKTEDKMHMSLFFDKKNGFAPTNEDALKILQFQSKFLNYRKKYEYKKNLWTKKDIDMLFITVDKISKKYAFQYLIEPELSYELKQQKQKEIEESDTKNILSKLKLYFDEHVHKKKLLTQEDYDKLREIEISDLCEEKLGLNNSNSINYEKEKILNESNKLSKKNIQIENFAVFSQKFWEEVSENLKNSQTARECQKTWLYYGCFEDEKKKWTEEEIKQLLFLSKKYKKREWKCIARELNTNRSPLSCFEQYIKINKLYDTKEKIKLERIAFNVLEDIQLQILVSILGDKNWYDIKKHMEILNTNIKRIEKRKNCHVIENEKKKKCINDEISYKRRYLRLINTKKEQKEHFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYE0</accession>
    <name>A0A1J1GYE0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycerol-3-phosphate 1-O-acyltransferase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00514500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530373.1">
        <property type="nucleotide sequence ID" value="XM_028673973.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYE0"/>
    <dbReference type="GeneID" id="39733678"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00514500"/>
    <dbReference type="OrthoDB" id="524544at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004366">
        <property type="term" value="F:glycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006655">
        <property type="term" value="P:phosphatidylglycerol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1130.10">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016222">
        <property type="entry name" value="G3P_O-acylTrfase_chlp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35695">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35695:SF1">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000431">
        <property type="entry name" value="Glycerol-3-P_O-acyltransfrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012633734" evidence="2">
        <location>
            <begin position="18"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="3">
        <location>
            <begin position="166"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="HXXXXD motif" evidence="1">
        <location>
            <begin position="189"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000431-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="390" mass="45980" checksum="06B67B17B95E6F51" modified="2017-02-15" version="1">MLAILIFLILEIIYVENLKKKPFYLKNNDFQYMTKSFNKNGHVKAYLSDLKTNNVKVSNILNDNSYEEAYKIIYDKLELLKKENSDNIDNINTFEGFLEKYKEEIKKYKSCSPQVFLEIFLKYIEVFKKYRYYSFPNVHKYDESLYEWSLKFWSQLIDEKNSKFMGIENIKKIEKWKEEGHNTIIFGNHHIEADANIIKYFFDIHGSQNISRNMIFIGGHKIRVDPLSRPFSVAANLLCIYSKKYIENPPHLKEEKILFNHKSLNALKNLLNEGKQIIWLAPSGGRDRKSSDGNIKISPFDPKIIQTFNIFAKRSKVKTHFVGLALYTYNICPPPNTIDIDEIEKTRSCSYTSVSLNLGEDLFDVYPNMKDEEITTNLYNYVNKLYNQIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYL1</accession>
    <name>A0A1J1GYL1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">LEM3/CDC50 family protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00360800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the CDC50/LEM3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529189.1">
        <property type="nucleotide sequence ID" value="XM_028672659.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYL1"/>
    <dbReference type="GeneID" id="39732138"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00360800"/>
    <dbReference type="OrthoDB" id="340608at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005045">
        <property type="entry name" value="CDC50/LEM3_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10926:SF0">
        <property type="entry name" value="CDC50, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10926">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03381">
        <property type="entry name" value="CDC50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015840">
        <property type="entry name" value="DUF284_TM_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="331"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR015840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="366" mass="43553" checksum="CF070E242520CE11" modified="2017-02-15" version="1">MKILKRKNENIKKKKRDLYYKKTSKFVRFLYKFIKWYRMEAEVGPIRAYKYSSVILFLIFLFIFNMIIGIIVLLLSNQYIECRIPYEYKGQSYTKYSIVRVTPEHCKGIGNLKELKGKLNVHYELQGLQQNHYRFVSSFKKEQLSGQIFLKKEDVSECHPFITFSEGGVNKILHPCGIFPWNVFSDSYIFYDREPDEFPFPTPIPIQQKVEDITIKYYRKFFKNPSAELINSHKDHVYFWMDEKLQSKSLQENKETNEKLVILPQTLKYDQAGKAIENSHFINWMIPSALNYIKRLYAKIDGPLVFPFYIYIENRLKISDTKIVVISNSTIYPGITLIGFIFIVVSLFAFILSILYIIRMRKYQFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYR8</accession>
    <name>A0A1J1GYR8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Translation initiation factor eIF2B subunit epsilon</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">eIF2B GDP-GTP exchange factor subunit epsilon</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00528500</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">Component of the translation initiation factor 2B (eIF2B) complex which is a heterodecamer of two sets of five different subunits: alpha, beta, gamma, delta and epsilon. Subunits alpha, beta and delta comprise a regulatory subcomplex and subunits epsilon and gamma comprise a catalytic subcomplex. Within the complex, the hexameric regulatory complex resides at the center, with the two heterodimeric catalytic subcomplexes bound on opposite sides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eIF-2B gamma/epsilon subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530509.1">
        <property type="nucleotide sequence ID" value="XM_028674125.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYR8"/>
    <dbReference type="GeneID" id="39733818"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00528500"/>
    <dbReference type="OMA" id="IVVTHHE"/>
    <dbReference type="OrthoDB" id="424572at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005851">
        <property type="term" value="C:eukaryotic translation initiation factor 2B complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03356">
        <property type="entry name" value="LbH_G1P_AT_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051956">
        <property type="entry name" value="eIF2B_epsilon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056764">
        <property type="entry name" value="LbH_EIF2B3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003307">
        <property type="entry name" value="W2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45887">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45887:SF1">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25084">
        <property type="entry name" value="LbH_EIF2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51363">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="W2" evidence="10">
        <location>
            <begin position="620"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="211"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="479"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="211"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="227"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="479"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG97708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="788" mass="93242" checksum="8A0C7773B6A2DFF2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYW3</accession>
    <name>A0A1J1GYW3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Translation initiation factor SUI1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00522400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DENR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530449.1">
        <property type="nucleotide sequence ID" value="XM_028674058.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYW3"/>
    <dbReference type="GeneID" id="39733757"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00522400"/>
    <dbReference type="OMA" id="WRKRFSC"/>
    <dbReference type="OrthoDB" id="277199at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001731">
        <property type="term" value="P:formation of translation preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002188">
        <property type="term" value="P:translation reinitiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11607">
        <property type="entry name" value="DENR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.780.10">
        <property type="entry name" value="SUI1-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050318">
        <property type="entry name" value="DENR/SUI1_TIF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046447">
        <property type="entry name" value="DENR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048517">
        <property type="entry name" value="DENR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001950">
        <property type="entry name" value="SUI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036877">
        <property type="entry name" value="SUI1_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12789:SF0">
        <property type="entry name" value="DENSITY-REGULATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12789">
        <property type="entry name" value="DENSITY-REGULATED PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21023">
        <property type="entry name" value="DENR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01253">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55159">
        <property type="entry name" value="eIF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50296">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SUI1" evidence="3">
        <location>
            <begin position="169"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="59"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="254" mass="30187" checksum="D02ECB679BE38752" modified="2017-02-15" version="1">MDELEKEFEKINLKYEDEEEQNEQEKISHRKLRYLKMKDKKDEKKRNKQNSKIVNNIKNKNDNKNEDEVKRKDDDDNNIIKEDEINSKIDESLNVSDNIEKDKKKYEPVFVEYCKICGMPYEYCEYGKFYNECKEENKEKYNYDIMNNEVDNNNKKQTKKIPKISNQKITIQKTTRARKKVVTVVTGLHTYVKLEKIAKIFSRFYACGSSVIKGTNNNPDQIDIQGDVEHNIAEIIMKNCPEVTEDKFVFLPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ07</accession>
    <name>A0A1J1GZ07_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="5">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00025400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="5">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530619.1">
        <property type="nucleotide sequence ID" value="XM_028674247.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ07"/>
    <dbReference type="GeneID" id="39728777"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00025400"/>
    <dbReference type="OMA" id="RIMSKEN"/>
    <dbReference type="OrthoDB" id="10256233at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="116"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="315"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="478" mass="57095" checksum="DDBE14814E958360" modified="2017-02-15" version="1">MFFIHILIFSFFCFFCFFFQIYSYNIININIKLNKYVNLKNKYKNFILKNSQRNFNYTVENFPSINEIINNKDDYFFKSNKTFSDLNVHKTLVEELKKNNINVASIIQSDLLDYYNKNYEKLKNIIIGAENGIGKTLSYIILILNHLLNQKKKNTCIIIFQYSNLLCNQCYDIIKLLSKNVKVKTINLKNEDKINLNKNHIIISTPVKFYHYMKENKEILINFFQNLKFLIIDEADVIFEKPYIKYMNYIFDEIKKIHDNFVSIITSSTLCNKGKKSIYNNIMKYIKNSVIIKTNYFHNIHPFINYHFINLPIYNINTKFEAIKKILQRENHKKVLIFCNTIKSCNQAFSLMKSVFDNIFIFNSSFKKTDQLIILEHFKNSQKPILVTTDIIYRGIDVKNITHLFHFDTPTNIIVYTHRNGRISRGASTGDIYIFNNLNDLITKKIYELHKNNVRFEELFSRKRSLRKNYKRELKNSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ69</accession>
    <name>A0A1J1GZ69_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LisH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00533500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530558.1">
        <property type="nucleotide sequence ID" value="XM_028674179.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ69"/>
    <dbReference type="GeneID" id="39733868"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00533500"/>
    <dbReference type="OrthoDB" id="376237at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="699" mass="83271" checksum="B94614B7860D8606" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZE9</accession>
    <name>A0A1J1GZE9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosducin-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">PhLP3</name>
        <name evidence="5" type="ORF">PGAL8A_00037900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosducin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530741.1">
        <property type="nucleotide sequence ID" value="XM_028674382.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZE9"/>
    <dbReference type="GeneID" id="39728903"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00037900"/>
    <dbReference type="OMA" id="LMEENCV"/>
    <dbReference type="OrthoDB" id="45518at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051498">
        <property type="entry name" value="Phosducin-like_chap/apop_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024253">
        <property type="entry name" value="Phosducin_thioredoxin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45809">
        <property type="entry name" value="VIRAL IAP-ASSOCIATED FACTOR HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45809:SF3">
        <property type="entry name" value="VIRAL IAP-ASSOCIATED FACTOR HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02114">
        <property type="entry name" value="Phosducin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosducin" evidence="4">
        <location>
            <begin position="135"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="275"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="26"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="314" mass="37404" checksum="A35B9D6C474F2E98" modified="2017-02-15" version="1">MSTTNPTNETTEWDDLQRKFGNLPPLEKEIKEEEIYLQNIDKIENENVLEKKNLKELNLMEENCVDEEYLKIIEKYKNDRINQINRNRALDIYGDIYEISKDNFITEINEASKKNPLNEYLEKSVDDKDEEEIKRKHKNIKGTYVVIHLYSDNVVACKVLNEILKHVANKHKYIKFTKGVYNRIIENYPEFKLPTILIYYNGTCIHQICNLLNHIKGGLNNLNIKSFEQFLNKYKILKYKNYVDSDISDNDNDEDYKNKNRVKTEKQYASFNMFNTKYKNNDDEDDESSSEEKEMRSRGYASSYLDSKIRLNKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZK9</accession>
    <name>A0A1J1GZK9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00043900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530805.1">
        <property type="nucleotide sequence ID" value="XM_028674454.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZK9"/>
    <dbReference type="GeneID" id="39728964"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00043900"/>
    <dbReference type="OMA" id="ILCINEY"/>
    <dbReference type="OrthoDB" id="377880at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="581"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="153"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="265"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="423"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="607"/>
            <end position="827"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="880" mass="105273" checksum="24976134C01D0EAD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZN7</accession>
    <name>A0A1J1GZN7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Aquaporin, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">AQP2</name>
        <name evidence="8" type="ORF">PGAL8A_00525700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530482.1">
        <property type="nucleotide sequence ID" value="XM_028674095.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZN7"/>
    <dbReference type="GeneID" id="39733790"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00525700"/>
    <dbReference type="OrthoDB" id="385251at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015250">
        <property type="term" value="F:water channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034294">
        <property type="entry name" value="Aquaporin_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19139">
        <property type="entry name" value="AQUAPORIN TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19139:SF199">
        <property type="entry name" value="MIP17260P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="305"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="347"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="381"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="475"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="520"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="546"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="132"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="625" mass="74193" checksum="899A1F3EA329D986" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZP9</accession>
    <name>A0A1J1GZP9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerases I, II, and III subunit RPABC5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00048300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530845.1">
        <property type="nucleotide sequence ID" value="XM_028674498.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZP9"/>
    <dbReference type="GeneID" id="39729008"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00048300"/>
    <dbReference type="OMA" id="MCHVDLI"/>
    <dbReference type="OrthoDB" id="10258858at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006360">
        <property type="term" value="P:transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000024">
        <property type="entry name" value="DNA-directed RNA polymerases I, II, and III subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00250">
        <property type="entry name" value="RNApol_arch_Rpo10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023580">
        <property type="entry name" value="RNA_pol_su_RPB10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020789">
        <property type="entry name" value="RNA_pol_suN_Zn-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000268">
        <property type="entry name" value="RPABC5/Rpb10"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003089">
        <property type="entry name" value="PRK04016.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23431:SF3">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23431">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC5 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01194">
        <property type="entry name" value="RNA_pol_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005653">
        <property type="entry name" value="RNA_pol_N/8_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46924">
        <property type="entry name" value="RNA polymerase subunit RPB10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01112">
        <property type="entry name" value="RNA_POL_N_8KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG98048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="69" mass="8251" checksum="4A207FB8704A78D1" modified="2017-02-15" version="1">MIIPVRCFTCGKLIGNLWNIYEKKLEEGISKSDALDELNLYRYCCRRMILTHADMMDKLLSYNIYERKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZQ0</accession>
    <name>A0A1J1GZQ0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">OTU-like cysteine protease, putative</fullName>
            <ecNumber evidence="2">3.4.22.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00436000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.22.-" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529581.1">
        <property type="nucleotide sequence ID" value="XM_028673094.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZQ0"/>
    <dbReference type="GeneID" id="39732892"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00436000"/>
    <dbReference type="OrthoDB" id="415023at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22751">
        <property type="entry name" value="OTU_plant_OTU9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050704">
        <property type="entry name" value="Peptidase_C85-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12419">
        <property type="entry name" value="OTU DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12419:SF111">
        <property type="entry name" value="OVARIAN TUMOR DOMAIN-CONTAINING DEUBIQUITINATING ENZYME 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02338">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OTU" evidence="1">
        <location>
            <begin position="98"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="226" mass="27186" checksum="D1593BCEFEA1CC7D" modified="2017-02-15" version="1">MCFNTKLLDLKYKYMKTRLKMLPNSENDDKIARKLNKNLNMRSLIYVLKAVIIIKQKRRLKRYTSLDRHIPFLRKNSLNKTHINGRKILENRLLAIGCELIQVSGDGNCLFRSISCNLFEKQKYHMYVRKRCVEYMLNFKDEYSIYFEDNAFYEYIKNMSKNGYWGDELCIKATADAFNCIVYIITSTSENWCLKYESKYKNNLKKYVFLAYSSPTHYDYFRLIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0G4</accession>
    <name>A0A1J1H0G4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LITAF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00062700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530985.1">
        <property type="nucleotide sequence ID" value="XM_028674654.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0G4"/>
    <dbReference type="GeneID" id="39729152"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00062700"/>
    <dbReference type="OMA" id="MYNPKQI"/>
    <dbReference type="OrthoDB" id="385162at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006629">
        <property type="entry name" value="LITAF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10601">
        <property type="entry name" value="zf-LITAF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00714">
        <property type="entry name" value="LITAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51837">
        <property type="entry name" value="LITAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="70"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="143"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="LITAF" evidence="3">
        <location>
            <begin position="33"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="482"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="398"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG98188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="509" mass="61105" checksum="95242510AF2B65A4" modified="2017-02-15" version="1">MNDYDLNGKNKLTEMNVLQHEMNDLNINDNVHNENENNQTENDLNEVKEVLNCNFCNKHVYPIVEKYTPMFVYIIVLLLFIFISFFTIFLLPLLYLTFKQKKYSCPLCKKKITSPEKIFKIKKENQILTFQFPKCAIIISVKYLILFLSLVFLIFLFYIIRKTSDFNLDNLAKGPYIKASWIEYLEDCGNKSQFRNKFYSIHNFKEKYYGNTIIWRGRFHHIKEGFFNSNSLFIRMNPSEYRYDKPDIRALFNNSLISQIENLQKNDFIEFECTLLEISKNRSSHLCLLWNVILLEKFEPKDFNVVDFIKHLSILDMISNNTNSNPFFINLDDKNNNARRSIKIVHFSNNAYKNPNSIHDTDQHMFNLLNNEMNNLNSDNSYIDQINKNPSFTNKNTDDEDEYDEDDMYEDNSDSNNFNHNEFFDNPDYEKAYNFEREFKKEKDDNSNYEEDNEKIYHKKKINIDMNEKINEKIVEDINENLKEKNEETNDEMNIRLKKEKNEEMDEQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H151</accession>
    <name>A0A1J1H151_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Protein-S-isoprenylcysteine O-methyltransferase</fullName>
            <ecNumber evidence="3 10">2.1.1.100</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00458500</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine + S-adenosyl-L-methionine = [protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:21672"/>
            <dbReference type="Rhea" id="RHEA-COMP:12125"/>
            <dbReference type="Rhea" id="RHEA-COMP:12126"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90510"/>
            <dbReference type="ChEBI" id="CHEBI:90511"/>
            <dbReference type="EC" id="2.1.1.100"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Endoplasmic reticulum membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.100" evidence="3 10"/>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529808.1">
        <property type="nucleotide sequence ID" value="XM_028673347.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H151"/>
    <dbReference type="GeneID" id="39733118"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00458500"/>
    <dbReference type="OMA" id="GLYKYMR"/>
    <dbReference type="OrthoDB" id="422086at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004671">
        <property type="term" value="F:protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007269">
        <property type="entry name" value="ICMT_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025770">
        <property type="entry name" value="PPMT_MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12714">
        <property type="entry name" value="PROTEIN-S ISOPRENYLCYSTEINE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12714:SF9">
        <property type="entry name" value="PROTEIN-S-ISOPRENYLCYSTEINE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04140">
        <property type="entry name" value="ICMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51564">
        <property type="entry name" value="SAM_ICMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="147"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="369"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="437"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG97005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="502" mass="61452" checksum="39A4DC311C6CE47B" modified="2017-02-15" version="1">MNITRYVILTFLLYTIILNYKIFIYLINTNLYELMEKKNLYKIFGYYLHNFLDYGFISIYITVGFLPNKNVYMKQSKSNYIFAKILLVYFLFFFLHFTINIFNNFPLNIFYLVITIFHLSEFFLSFLHNKDNHNFYNFLVNPNRLYVYFFICTLIEYYAKIFLFVILSIFEKNINKKFLHKALLFNLFFLKNYIENYGNCSYSYFNAIKVDNFNLSDTKEMSERIEIFKNCKYYNNQIMDIHLSKRKMLKENHLTCLLNNLFIRDTSDKKILLHNNEEIEYNEFKRKTNENYKTTEKYKNIKDNTGIFTYGKCIFGNITFKNIIDKYMDNLFIKTYDLNDSFFQKIILKYKGIFYKYELPKISKKLYNYYLYVILSSLVLSLIGLFLRLFGIIQCSSNFSFYVLSSHSLRKKNMKKEHHLVKKGLYKYMRHPCYTGWFYYSLFLQLFLFNIFCFFLSFIISWAFLYRTIKIEERNLLKCYNEEYRKYKEETPHIYIPFINNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1C3</accession>
    <name>A0A1J1H1C3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">28 kDa ookinete surface protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">P28</name>
        <name evidence="3" type="ORF">PGAL8A_00490200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530125.1">
        <property type="nucleotide sequence ID" value="XM_028673698.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1C3"/>
    <dbReference type="SMR" id="A0A1J1H1C3"/>
    <dbReference type="GeneID" id="39733435"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00490200"/>
    <dbReference type="OMA" id="DYAVCTN"/>
    <dbReference type="OrthoDB" id="10045365at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.90.20.10">
        <property type="entry name" value="Plasmodium vivax P25 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009618961" evidence="1">
        <location>
            <begin position="22"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="2">
        <location>
            <begin position="93"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="222" mass="24543" checksum="390234FD8AC82578" modified="2017-02-15" version="1">MKIPSLYFFFFIQIAIILTIAAPSDDEPCKNGYLIEMSNHIECKCNNDYVLTNRYECEPKNKCTSLEDTNKPCADYARCLEDPYKDNKSNFYCLCNRGYIQYEDKCIQAECNYKECGEGKCVWDGIHEDGAFCSCNIGKVINPEDNNKCTKDGDTKCTLECAQGKKCIKHDVYYMCGNDNSGSGSGGGGGGGNSPPPSSGNSTLSLFNALNIVFLIAVIYII</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H216</accession>
    <name>A0A1J1H216_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ferredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00514400</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
        <text evidence="8">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the 2Fe2S plant-type ferredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530372.1">
        <property type="nucleotide sequence ID" value="XM_028673972.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H216"/>
    <dbReference type="GeneID" id="39733677"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00514400"/>
    <dbReference type="OMA" id="RNKLFYN"/>
    <dbReference type="OrthoDB" id="1885901at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022900">
        <property type="term" value="P:electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000014">
        <property type="entry name" value="Ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010241">
        <property type="entry name" value="Fd_pln"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02008">
        <property type="entry name" value="fdx_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43112">
        <property type="entry name" value="FERREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43112:SF3">
        <property type="entry name" value="FERREDOXIN-2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="5 8" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="7 8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012498251" description="Ferredoxin" evidence="9">
        <location>
            <begin position="20"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="10">
        <location>
            <begin position="93"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG97571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="188" mass="22147" checksum="B1F8B42D6A9441FA" modified="2017-02-15" version="1">MNLAILFLILLFSIEYSNTYKLNNNKISFNYMFGNKNYIKNRKNYFCSKFLSGLINYNKESCFFINKKYLPNVNAYCNKKRFFSSKEKNKLFYTITLRTNEGEKKIECNEDEYILDASERQNVELPYSCRGGSCSTCAAKLIEGKVDNDEQSYLDEEQLKQNYILLCTCYPKSDCVIETHKEDELHDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2K5</accession>
    <name>A0A1J1H2K5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00530000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530524.1">
        <property type="nucleotide sequence ID" value="XM_028674141.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2K5"/>
    <dbReference type="GeneID" id="39733833"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00530000"/>
    <dbReference type="OrthoDB" id="392873at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="493"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="112"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="519"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="569" mass="67437" checksum="B36013E1ECBC79E5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H369</accession>
    <name>A0A1J1H369_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Amino acid transporter, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00037000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530732.1">
        <property type="nucleotide sequence ID" value="XM_028674372.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H369"/>
    <dbReference type="GeneID" id="39728894"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00037000"/>
    <dbReference type="OMA" id="LVMFVEA"/>
    <dbReference type="OrthoDB" id="391298at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SNF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="273"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="310"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="415"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="446"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="489"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="523"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="584"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="626"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="650"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="688"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="718"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="790"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="835"/>
            <end position="858"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="899" mass="107754" checksum="DA10656E1F8F828B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3I1</accession>
    <name>A0A1J1H3I1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00048200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530844.1">
        <property type="nucleotide sequence ID" value="XM_028674497.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3I1"/>
    <dbReference type="GeneID" id="39729007"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00048200"/>
    <dbReference type="OMA" id="CFHLPNG"/>
    <dbReference type="OrthoDB" id="385103at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG98047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="103" mass="12095" checksum="0D1209DBAB608029" modified="2017-02-15" version="1">MDEFSKGIVFPLKGENIEKEKKIEVENHIQINFHLPCGNTEVMYEKASIEVGYLKLMLSKKLQKPYNQIKLTYNNNVMLDPLSIIDIIKEKFQFIDIDVNYID</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3K5</accession>
    <name>A0A1J1H3K5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00050600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530868.1">
        <property type="nucleotide sequence ID" value="XM_028674524.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3K5"/>
    <dbReference type="GeneID" id="39729031"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00050600"/>
    <dbReference type="OMA" id="FEWPLTI"/>
    <dbReference type="OrthoDB" id="370360at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012746341" evidence="1">
        <location>
            <begin position="25"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="249" mass="30031" checksum="E0659FBB52AA8BB8" modified="2017-02-15" version="1">MLLMKIFLQNFFFIFIQHILLIQTENIKLKNYAFNRKHFMLKILNEKNILIYHRKKYLNLKQKKKVKRVYSQAYLVFDIIKIFGRISDKELLGHVISHNNEFIELDKNKKKKKWEILFDNNYINFDLLKKFLKNNKFEWPLTVNSGQIKNQGSINIPENCRKISEEFRNKNKTSKINLKIINDYVSELPISNDAIQCVFSSFSDFDDLTKDHFINKIHEWAPSDGIVDWYTFVYNLKEEPSDNIKRFFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2012-05-16" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>H7CDX0</accession>
    <name>H7CDX0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Apicoplast ribosomal protein L2, putative</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="6">Large subunit ribosomal protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpl2</name>
        <name evidence="7" type="synonym">RPL2</name>
        <name evidence="7" type="ORF">PGAL8A_API01400</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <geneLocation type="apicoplast" evidence="6"/>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Mol. Biol. Evol." volume="29" first="2095" last="2099">
            <title>The Plasmodium Apicoplast Genome: Conserved Structure and Close Relationship of P. ovale to Rodent Malaria Parasites.</title>
            <authorList>
                <person name="Arisue N."/>
                <person name="Hashimoto T."/>
                <person name="Mitsui H."/>
                <person name="Palacpac N.M.Q."/>
                <person name="Kaneko A."/>
                <person name="Kawai S."/>
                <person name="Hasegawa M."/>
                <person name="Tanabe K."/>
                <person name="Horii T."/>
            </authorList>
            <dbReference type="PubMed" id="22396524"/>
            <dbReference type="DOI" id="10.1093/molbev/mss082"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">A8</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
    <dbReference type="EMBL" id="AB649424">
        <property type="protein sequence ID" value="BAL70740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LN835293">
        <property type="protein sequence ID" value="CRG98229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009325456.1">
        <property type="nucleotide sequence ID" value="NC_031963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="H7CDX0"/>
    <dbReference type="GeneID" id="30315798"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_API01400"/>
    <dbReference type="OrthoDB" id="1298661at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Apicoplast API"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.950.10">
        <property type="entry name" value="Ribosomal protein L2, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002171">
        <property type="entry name" value="Ribosomal_uL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022669">
        <property type="entry name" value="Ribosomal_uL2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014726">
        <property type="entry name" value="Ribosomal_uL2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691:SF5">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691">
        <property type="entry name" value="RIBOSOMAL PROTEIN L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03947">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002158">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01382">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0933">Apicoplast</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL2 C-terminal" evidence="5">
        <location>
            <begin position="109"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="217"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="230"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAL70740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG98229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="245" mass="29003" checksum="81C30771A9A81682" modified="2012-05-16" version="1">MILKLKKYNIYKYLKNFGKNNKGYITIKNKGGGKLKYNYKLIDFWYDNYNIKFNYKIILFKKLKNYFRNNYIGCILYLSLMLNHLQKYIILQYNYILNSIYYITNINNIKQGSYLQLKYCKLGTYIYNISINNKGGIFARSAGTFAQILTFYKNFVYIKLPSKQYKYILNTCFCYIGINSNIFYNKYKIKNAGYNIYYNKKSHVRGKAMNVCDHPHGGGKGKTSIGRKYPCSKKGLHSKGYKTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKX4</accession>
    <name>A0A1J1GKX4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00077100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525886.1">
        <property type="nucleotide sequence ID" value="XM_028670089.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729296"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00077100"/>
    <dbReference type="OMA" id="KHIASEQ"/>
    <dbReference type="OrthoDB" id="10254663at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="31"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="472"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1095"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="129"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="343"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="498"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="603"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="764"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1027"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="36"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1095"/>
            <end position="1111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1693" mass="199938" checksum="2A598912D5A31AC7" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLA4</accession>
    <name>A0A1J1GLA4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alpha/beta hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00082000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525938.1">
        <property type="nucleotide sequence ID" value="XM_028670666.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLA4"/>
    <dbReference type="GeneID" id="39729344"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00082000"/>
    <dbReference type="OMA" id="MLFNIYV"/>
    <dbReference type="OrthoDB" id="329737at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="273" mass="31170" checksum="8B91119C37CB7F5F" modified="2017-02-15" version="1">MKENVKILYIHGFHVFGESKKQKLIEKVVGKKNLITTGINQRRSISSFIFFLIFIICVMLFNIYVSYRFSVTSIFVITIALSVIITIIIYFIGSHLILYYIMKKSIKQAEQKVQMYNPDVVVGIYFGAVVAMNLNYKNGKKSLVLISPSVKTFQKFTHNLEPDLSTFPYVIIVNGSNDMVTPVNVCEELISTVPLGKGRLEVVEDNHYYSKLKESDFKAWIKEAIYKPSTCVVNVAKHLKNEKMGKKITVNTQSFNEFSSFENSNSKEDDPLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLU6</accession>
    <name>A0A1J1GLU6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Prohibitin-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00090100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526019.1">
        <property type="nucleotide sequence ID" value="XM_028671566.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLU6"/>
    <dbReference type="GeneID" id="39729425"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00090100"/>
    <dbReference type="OrthoDB" id="428964at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="294" mass="35435" checksum="59A17B394DCF255B" modified="2017-02-15" version="1">MKKNLFTLRFHLQNVRYYSLNKKNLININKIIKNTDGFHEKREMFRTNNFINEIKKYNKIANKENIIKKENIINKENIINKENLVSKENLVSTDRIERDDKIEKVEKIKLLRLKNFKLITFCVITTLFFYFTIKKVPEGYVCLVENINDKKVLPYIYDDKMTFFFNPLKYKVILMRTVPIQKKYVNIYETLDKKKIKVVLTVKMKPKIPFIIEIYSSFGVNYSSKYIEKEMNLDIKNVVKKYKYNTFFEEDYTSNKNEISVDDIVDQIMERFYDCSIFHKVILLDATILFEKVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLZ6</accession>
    <name>A0A1J1GLZ6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tubulin-specific chaperone A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00105300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the TBCA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526169.1">
        <property type="nucleotide sequence ID" value="XM_028673232.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLZ6"/>
    <dbReference type="GeneID" id="39729578"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00105300"/>
    <dbReference type="OMA" id="GISKKCT"/>
    <dbReference type="OrthoDB" id="296187at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048487">
        <property type="term" value="F:beta-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007023">
        <property type="term" value="P:post-chaperonin tubulin folding pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007021">
        <property type="term" value="P:tubulin complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004226">
        <property type="entry name" value="TBCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036126">
        <property type="entry name" value="TBCA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21500">
        <property type="entry name" value="TUBULIN-SPECIFIC CHAPERONE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21500:SF0">
        <property type="entry name" value="TUBULIN-SPECIFIC CHAPERONE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02970">
        <property type="entry name" value="TBCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46988">
        <property type="entry name" value="Tubulin chaperone cofactor A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0493">Microtubule</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU364030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="165" mass="19674" checksum="D61B91904AAC975A" modified="2017-02-15" version="1">MKNLLSDFKLLKINHGAVKRLFKELIYYEKEEEELKSKVNKLKDENKHEGEIKKAEEILQETIRVLPHINTSLHKTLKKLCNIIYENFEDILEINGKKIEFSNKYSEEELKQNFATLYEEFYQEINDINQTLENVFLHIKDAEIPTCNRIDNNSLLLPKEEYVDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM05</accession>
    <name>A0A1J1GM05_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DnaJ protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00117000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526286.1">
        <property type="nucleotide sequence ID" value="XM_028674533.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM05"/>
    <dbReference type="GeneID" id="39729695"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00117000"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017964">
        <property type="entry name" value="DNA-dir_DNA_pol_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43096">
        <property type="entry name" value="DNAJ HOMOLOG 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43096:SF52">
        <property type="entry name" value="DNAJ HOMOLOG 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00116">
        <property type="entry name" value="DNA_POLYMERASE_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="605"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="629"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="4">
        <location>
            <begin position="111"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="28"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="654" mass="77483" checksum="34CAAE4268331115" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM94</accession>
    <name>A0A1J1GM94_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00126700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526382.1">
        <property type="nucleotide sequence ID" value="XM_028674786.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM94"/>
    <dbReference type="GeneID" id="39729792"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00126700"/>
    <dbReference type="OMA" id="HIEKSEH"/>
    <dbReference type="OrthoDB" id="372263at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="119"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="625"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="15"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="122"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="138"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="191"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="212"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="229"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="239"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="790" mass="93563" checksum="A867E08E543949C9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMC6</accession>
    <name>A0A1J1GMC6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Histone S-adenosyl methyltransferase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00128900</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526404.1">
        <property type="nucleotide sequence ID" value="XM_028674810.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMC6"/>
    <dbReference type="GeneID" id="39729814"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00128900"/>
    <dbReference type="OrthoDB" id="10265243at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033588">
        <property type="term" value="C:elongator holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002926">
        <property type="term" value="P:tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.30.20:FF:000011">
        <property type="entry name" value="Elongator complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039661">
        <property type="entry name" value="ELP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034687">
        <property type="entry name" value="ELP3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032432">
        <property type="entry name" value="Radical_SAM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11135:SF2">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11135">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16199">
        <property type="entry name" value="Radical_SAM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01086">
        <property type="entry name" value="elongater_protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00344">
        <property type="entry name" value="ELP3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1006"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="domain" description="Elp3/MiaA/NifB-like radical SAM core" evidence="12">
        <location>
            <begin position="329"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="207"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="218"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG93582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1035" mass="123115" checksum="CCE7AD38BA4863B9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMD0</accession>
    <name>A0A1J1GMD0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00130500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526422.1">
        <property type="nucleotide sequence ID" value="XM_028674830.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729830"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00130500"/>
    <dbReference type="OMA" id="NEIKWIC"/>
    <dbReference type="OrthoDB" id="514276at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="3">
        <location>
            <begin position="66"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="66"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="496"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="846"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="922"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="496"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="509"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="535"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="642"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="658"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="683"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="713"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="732"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="757"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="771"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="846"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="867"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="922"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="988"/>
            <end position="997"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1295" mass="148951" checksum="9585F0807B163ECB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMD9</accession>
    <name>A0A1J1GMD9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00123100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526346.1">
        <property type="nucleotide sequence ID" value="XM_028674746.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMD9"/>
    <dbReference type="GeneID" id="39729756"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00123100"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013289335" evidence="2">
        <location>
            <begin position="23"/>
            <end position="1262"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="3">
        <location>
            <begin position="484"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="527"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="735"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="539"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="557"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="580"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="595"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="759"/>
            <end position="772"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1262" mass="145341" checksum="42502E658043B814" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMG1</accession>
    <name>A0A1J1GMG1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Acylphosphatase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00133700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526454.1">
        <property type="nucleotide sequence ID" value="XM_028674865.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMG1"/>
    <dbReference type="GeneID" id="39729862"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00133700"/>
    <dbReference type="OMA" id="PAKKKMH"/>
    <dbReference type="OrthoDB" id="406969at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001792">
        <property type="entry name" value="Acylphosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51160">
        <property type="entry name" value="ACYLPHOSPHATASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acylphosphatase-like" evidence="2">
        <location>
            <begin position="91"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="211" mass="25645" checksum="B10901F93B69D4CB" modified="2017-02-15" version="1">MIPTPVSKKIRSRLNLSIQKKPHFLFRQNVLLDKREKWEPKLRKGHPQFIKQFDILNRQVTGFRKYKQVTIKREEIKKNYDITNFHEVKSKFRFEINGYFGDNGNIFCEELYRTAKRMFIVGWIKCRKRFAMGHFQGDSYAISYLRHWFDMYSSDTNRIDKLKIFDENHGIPNLDYYNITIVKDYRSPAKKKMHMIQSQDFLKTKKLFNIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMP0</accession>
    <name>A0A1J1GMP0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Transmembrane protein 234</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00140800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM234 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526524.1">
        <property type="nucleotide sequence ID" value="XM_028674943.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMP0"/>
    <dbReference type="GeneID" id="39729932"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00140800"/>
    <dbReference type="OMA" id="TYITEVC"/>
    <dbReference type="OrthoDB" id="43458at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018908">
        <property type="entry name" value="TMEM234"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28668">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28668:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10639">
        <property type="entry name" value="TMEM234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009618913" description="Transmembrane protein 234" evidence="7">
        <location>
            <begin position="19"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="117" mass="13504" checksum="E6C900D7ABCC049B" modified="2017-02-15" version="1">MYFILYLVIGFLWGCTNAYMKKGCKDENTEKNIIKDIISIFKNLNIIIPYILNQIGSLLYYYLLSESDISLVMPLSNASSFFFTYITEIIIFKKSITYKSILGLILICSGLFMCVNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNF3</accession>
    <name>A0A1J1GNF3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">6-cysteine protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00170600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG93999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526820.1">
        <property type="nucleotide sequence ID" value="XM_028670027.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNF3"/>
    <dbReference type="GeneID" id="39730233"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00170600"/>
    <dbReference type="OMA" id="YGHREFK"/>
    <dbReference type="OrthoDB" id="380237at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2860">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038160">
        <property type="entry name" value="6_CYS_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012927139" evidence="2">
        <location>
            <begin position="22"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="693"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="716"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="757"/>
            <end position="766"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="830" mass="94285" checksum="B59C44D36AC013B5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNG4</accession>
    <name>A0A1J1GNG4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Elongation factor 1-alpha, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00163400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526746.1">
        <property type="nucleotide sequence ID" value="XM_028675190.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNG4"/>
    <dbReference type="GeneID" id="39730159"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00163400"/>
    <dbReference type="OMA" id="SPPCYTP"/>
    <dbReference type="OrthoDB" id="407705at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01883">
        <property type="entry name" value="EF1_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001191">
        <property type="entry name" value="Elongation factor 1-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050100">
        <property type="entry name" value="TRAFAC_GTPase_members"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23115">
        <property type="entry name" value="TRANSLATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="3">
        <location>
            <begin position="5"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="286" mass="31872" checksum="D13139D92CA20767" modified="2017-02-15" version="1" fragment="single">MGKEKTHINLVVIGHVDSGKSTTTGHIIYKLGGIDRRTIEKFEKESAEMGKGSFKYAWVLDKLKAERERGITIDIALWKFETPRYYFTVIDAPGHKDFIKNMITGTSQADVALLIVPAEVGGFEGAFSKEGQTKEHALLAFTLGVKQIVVGVNKMDTVKYSEERYEEIKKEVRDYLKKVGYAADKVDFIPISGFEGDNLIEKSDKTPWYKGRTLIEALDTMEPPKRPFDKPLRIPLQGVYKIGGIGTVPVGRVETGILKAGMVLNFAPSAVVSECKSVEMHKEVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNJ8</accession>
    <name>A0A1J1GNJ8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ER lumen protein-retaining receptor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00160000</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the ERD2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526713.1">
        <property type="nucleotide sequence ID" value="XM_028675153.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNJ8"/>
    <dbReference type="GeneID" id="39730125"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00160000"/>
    <dbReference type="OMA" id="WKSRSCE"/>
    <dbReference type="OrthoDB" id="7694678at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046923">
        <property type="term" value="F:ER retention sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006621">
        <property type="term" value="P:protein retention in ER lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000133">
        <property type="entry name" value="ER_ret_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10585">
        <property type="entry name" value="ER LUMEN PROTEIN RETAINING RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00810">
        <property type="entry name" value="ER_lumen_recept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00660">
        <property type="entry name" value="ERLUMENR"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00951">
        <property type="entry name" value="ER_LUMEN_RECEPTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00952">
        <property type="entry name" value="ER_LUMEN_RECEPTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10 11 12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="62"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="125"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG93892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="221" mass="26402" checksum="F39D23288F99B0AC" modified="2017-02-15" version="1">MNAFRLIGDILHLVSMYILIIKLKKSKNCIGISCRMQELYLIVFLCRYIDLFFVFVSLYNTIMKITFILTIAYTIYLIRFKLPISQTYNRKVDSFKSEKYLIPPCIVLSLLTCKTYNLYNILWTFSIWLESVAILPQLVLLEKQREVENITSHYVITMGLYRAFYILNWIYRYFFDEKPYINVVGWIGGLIQTLLYIDFFYYFALAKWYGKKLVLPFNGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNY0</accession>
    <name>A0A1J1GNY0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00382100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526938.1">
        <property type="nucleotide sequence ID" value="XM_028670158.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNY0"/>
    <dbReference type="GeneID" id="39732351"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00382100"/>
    <dbReference type="OrthoDB" id="379364at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="614" mass="73980" checksum="E322678307370684" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP47</accession>
    <name>A0A1J1GP47_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Plasmodium RESA N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00178000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000021">
        <property type="protein sequence ID" value="CRG94068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526889.1">
        <property type="nucleotide sequence ID" value="XM_028670104.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP47"/>
    <dbReference type="GeneID" id="39730307"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00178000"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="210" mass="25967" checksum="D3ACF7CC53C0DAE1" modified="2017-02-15" version="1">MKGYLDNSVEIQYKKYTEIYRNLLFSRILRLFCLSLLFFLIQYVSKSKNEVFFELKESKVYSRKLMENEEEKIKIFQDNTDCSIVNLWASQRAKWRKGNYEMRKMAHEEWKRECLENNINDSMWINKTWFNWRFKSTEQILKKMGEDHINFLCFLNTFPSYNSIYEYLENMKKSLENYHELILNNWRCYMNDSINDWKEQRKNSLKKDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPF5</accession>
    <name>A0A1J1GPF5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Zinc finger protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00389200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527009.1">
        <property type="nucleotide sequence ID" value="XM_028670237.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPF5"/>
    <dbReference type="GeneID" id="39732422"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00389200"/>
    <dbReference type="OrthoDB" id="6270329at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="459"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="30"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="330"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="334"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="350"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="513" mass="61006" checksum="742AEAFD90F27B35" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPH1</accession>
    <name>A0A1J1GPH1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Transcriptional coactivator ADA2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ADA2</name>
        <name evidence="11" type="ORF">PGAL8A_00390800</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527025.1">
        <property type="nucleotide sequence ID" value="XM_028670254.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732438"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00390800"/>
    <dbReference type="OMA" id="SEKCEHY"/>
    <dbReference type="OrthoDB" id="270417at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02335">
        <property type="entry name" value="ZZ_ADA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000366">
        <property type="entry name" value="Transcriptional coactivator ADA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041983">
        <property type="entry name" value="ADA2-like_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055141">
        <property type="entry name" value="TADA2A_B-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12374:SF20">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTER 2-ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12374">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTOR 2 ADA2 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22941">
        <property type="entry name" value="TADA2A-like_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25299">
        <property type="entry name" value="ZZ_ADA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00291">
        <property type="entry name" value="ZnF_ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01357">
        <property type="entry name" value="ZF_ZZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50135">
        <property type="entry name" value="ZF_ZZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ZZ-type" evidence="8">
        <location>
            <begin position="1474"/>
            <end position="1534"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="10">
        <location>
            <begin position="1533"/>
            <end position="1593"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="9">
        <location>
            <begin position="1536"/>
            <end position="1593"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="7">
        <location>
            <begin position="1538"/>
            <end position="1589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="694"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1327"/>
            <end position="1361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="2016"/>
            <end position="2083"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="2105"/>
            <end position="2241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="2287"/>
            <end position="2310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="2335"/>
            <end position="2363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="2388"/>
            <end position="2411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="2435"/>
            <end position="2459"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="131"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1703"/>
            <end position="1730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="694"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="768"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="2020"/>
            <end position="2042"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="2051"/>
            <end position="2067"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="2068"/>
            <end position="2080"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="2117"/>
            <end position="2140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="2149"/>
            <end position="2166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="2167"/>
            <end position="2219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="2290"/>
            <end position="2302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="2343"/>
            <end position="2354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="2388"/>
            <end position="2397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="2398"/>
            <end position="2411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="2446"/>
            <end position="2459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG94204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2459" mass="293159" checksum="0B9B108AFB716801" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPP3</accession>
    <name>A0A1J1GPP3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="8">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00069000</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="8">The helicase domain is involved in the stimulation of RELA transcriptional activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG92986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525808.1">
        <property type="nucleotide sequence ID" value="XM_028672421.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPP3"/>
    <dbReference type="GeneID" id="39729215"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00069000"/>
    <dbReference type="OMA" id="KRQQVKF"/>
    <dbReference type="OrthoDB" id="1191041at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003877">
        <property type="entry name" value="SPRY_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00622">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00449">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="11">
        <location>
            <begin position="2"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="300"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="527"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="6">
        <location>
            <begin position="2"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG92986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="788" mass="91853" checksum="11EEFC46B761EE60" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ11</accession>
    <name>A0A1J1GQ11_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">40S ribosomal protein S19, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPS19</name>
        <name evidence="4" type="ORF">PGAL8A_00192600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000029">
        <property type="protein sequence ID" value="CRG94528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527343.1">
        <property type="nucleotide sequence ID" value="XM_028670607.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ11"/>
    <dbReference type="GeneID" id="39730451"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00192600"/>
    <dbReference type="OrthoDB" id="428974at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000118">
        <property type="entry name" value="40S ribosomal protein S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001266">
        <property type="entry name" value="Ribosomal_eS19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11710">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11710:SF0">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01090">
        <property type="entry name" value="Ribosomal_S19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01413">
        <property type="entry name" value="Ribosomal_S19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="172" mass="20173" checksum="562AF8C4473BB428" modified="2017-02-15" version="1">MAEEFTEEIVTVNKRLLEPIPFVRTNNCIKDVDAELFIKSYANYLKLHNKITFPKWCNFVKTGKGRKLAPLNEDWYFIKASSILRRLYLHPDIGIGHLRRQFSYKQRRGVAPNHTSLASGKILRSILQQFENIGYVEQNPKKKGRRLTTKGENAINNFARYINKKVYKLDKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ36</accession>
    <name>A0A1J1GQ36_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein kinase c inhibitor-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00110400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526221.1">
        <property type="nucleotide sequence ID" value="XM_028673810.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ36"/>
    <dbReference type="GeneID" id="39729630"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00110400"/>
    <dbReference type="OMA" id="QQLGWPP"/>
    <dbReference type="OrthoDB" id="672793at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01276">
        <property type="entry name" value="PKCI_related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.428.10:FF:000005">
        <property type="entry name" value="Histidine triad nucleotide-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019808">
        <property type="entry name" value="Histidine_triad_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001310">
        <property type="entry name" value="Histidine_triad_HIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23089">
        <property type="entry name" value="HISTIDINE TRIAD HIT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00332">
        <property type="entry name" value="HISTRIAD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00892">
        <property type="entry name" value="HIT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013153648" evidence="3">
        <location>
            <begin position="22"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="HIT" evidence="4">
        <location>
            <begin position="75"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-AMP-histidine intermediate" evidence="1">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR601310-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="184" mass="20980" checksum="3C199B73DDAD17AC" modified="2017-02-15" version="1">MRLRIIFILFIFLCLMKAIESFKNSLKNIVLNCFIRTSYSNKCLTRVINKKLAKMADEEEKALLAAGTDENGSSIFGKIANGEIKVDLVYEDDKVMAFNDINPQAPVHILVIPKNRNGLTRLSKAEEKHKEILGHLMWAVAEIVRRNNLGDFRLVVNNGPEACQSVYYLHLHILAKRQMKWPPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQF8</accession>
    <name>A0A1J1GQF8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pv-fam-g protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00214000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527558.1">
        <property type="nucleotide sequence ID" value="XM_028670846.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQF8"/>
    <dbReference type="GeneID" id="39730667"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00214000"/>
    <dbReference type="OMA" id="IHTQPNP"/>
    <dbReference type="OrthoDB" id="371235at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="172" mass="20011" checksum="72AA89DEEFF9901A" modified="2017-02-15" version="1">MDNLYYFMVQNNSVQPIIVRQPSAIIIHSQPKLPITLDLPSQNIILKSDEPQPIIVRQQNPNVIIQKPQNEFYNNPKLAVGLHEKLNEINMHNLNIMDERNNENINALNNSQCIDHVDPSYIYDNHNIAYTNKNIPINNMYFNYTALDNENKYAHYNTMPYSINNAAYINPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQM1</accession>
    <name>A0A1J1GQM1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Polyprenol reductase, putative</fullName>
            <ecNumber evidence="7">1.3.1.94</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00215200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.94" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527570.1">
        <property type="nucleotide sequence ID" value="XM_028670859.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQM1"/>
    <dbReference type="GeneID" id="39730679"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00215200"/>
    <dbReference type="OMA" id="WSLHGKN"/>
    <dbReference type="OrthoDB" id="5788137at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003865">
        <property type="term" value="F:3-oxo-5-alpha-steroid 4-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160198">
        <property type="term" value="F:polyprenal reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016095">
        <property type="term" value="P:polyprenol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001104">
        <property type="entry name" value="3-oxo-5_a-steroid_4-DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039698">
        <property type="entry name" value="Dfg10/SRD5A3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14624">
        <property type="entry name" value="DFG10 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14624:SF0">
        <property type="entry name" value="POLYPRENOL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02544">
        <property type="entry name" value="Steroid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50244">
        <property type="entry name" value="S5A_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="241"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="3-oxo-5-alpha-steroid 4-dehydrogenase C-terminal" evidence="6">
        <location>
            <begin position="156"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG94755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="285" mass="34413" checksum="9944AD28E833C2D9" modified="2017-02-15" version="1">MIHFYFKNIDFMKILFFFYHVIVIFLLLISFYFKPISQWALHGKNLFIKLEKGENENKSKIYKLKKKIDNIIIPKVYFLHFYIIGFVINSILVFQDFYQNYINERRVFDFISYTNIIFEIHLLRRLLEQLLVVRTTSKSFMHIFSYLLGISFYMVTPFSLYNSDKNEYSKLNLISVILFLFGNLIQFDSHVRLAKLRPKDIRKNDVLYKVPYGGFFYYVSCPHYFAEILIYLSFFMLNTNFISLLNFVMVSLILIVNGLKTHNWYIKILKDTYPKQRKAIFPFIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQZ1</accession>
    <name>A0A1J1GQZ1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00232600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527742.1">
        <property type="nucleotide sequence ID" value="XM_028671050.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQZ1"/>
    <dbReference type="GeneID" id="39730853"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00232600"/>
    <dbReference type="OMA" id="YVYIQKD"/>
    <dbReference type="OrthoDB" id="372547at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="23"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="187" mass="22397" checksum="94C4C4DEECE4CD7E" modified="2017-02-15" version="1">MKEYILFQNSSNNIYTFESYEKIIVKITFIASTITFFFSILSIVFVNMFPQDENNKYVDININIKDEKKPKTYLYIQKDTSSFSNTEIDKSDSDTCNDTFNSENEKEKEISENREKEIEMNKEREEMNEKEKLKKEDNVEEKEKEKTTNEKQQENENVIDKGESIIQNKDEEEYKEKQNKVIRIVIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR03</accession>
    <name>A0A1J1GR03_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">U1 snRNA associated protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00211900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Luc7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527537.1">
        <property type="nucleotide sequence ID" value="XM_028670823.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR03"/>
    <dbReference type="GeneID" id="39730646"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00211900"/>
    <dbReference type="OMA" id="PCTRIHD"/>
    <dbReference type="OrthoDB" id="153872at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006376">
        <property type="term" value="P:mRNA splice site recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004882">
        <property type="entry name" value="Luc7-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12375">
        <property type="entry name" value="RNA-BINDING PROTEIN LUC7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03194">
        <property type="entry name" value="LUC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="234"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="87"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="151"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="234"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="252"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="281"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="294"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="309"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="320" mass="38079" checksum="D02C7307D0E6070F" modified="2017-02-15" version="1">MEEMRSLLDSLMGKDRNEMDSQKKKYSFKDDNVCKYYLIDFCPHDLFPNTKSDIGRCKNIHSEVLKEQLENDENYKYYLAKYQQKFMKTLEKIIEVADIKIEKSKEKLKQLSVNCKNTFDKKSKIESINNHICNLLKQSEEAGEKGDLIKATSFNNQITMLHAEIKRLNEENDKANETNLKVCQVCGAMQSVGDVIQRFENHVNGKQHLGFEKIRNTLDKLKVGIKEREEMIEKHRKMKYKNNNHMKRKRNSHENSDKRRSSDYKSSKHHRSPERTDRIYHSRKSKRSRRHSSSYRSISNSSYCSNDRYRKHSSRHKKDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR15</accession>
    <name>A0A1J1GR15_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA 3'-terminal phosphate cyclase-like protein, putative</fullName>
            <ecNumber evidence="3">6.5.1.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00230500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.4" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527722.1">
        <property type="nucleotide sequence ID" value="XM_028671028.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR15"/>
    <dbReference type="GeneID" id="39730832"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00230500"/>
    <dbReference type="OMA" id="FFMNNLK"/>
    <dbReference type="OrthoDB" id="1911237at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003963">
        <property type="term" value="F:RNA-3'-phosphate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000479">
        <property type="term" value="P:endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.20">
        <property type="entry name" value="RNA 3'-terminal phosphate cyclase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013791">
        <property type="entry name" value="RNA3'-term_phos_cycl_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023797">
        <property type="entry name" value="RNA3'_phos_cyclase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037136">
        <property type="entry name" value="RNA3'_phos_cyclase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000228">
        <property type="entry name" value="RNA3'_term_phos_cyc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11096">
        <property type="entry name" value="RNA 3' TERMINAL PHOSPHATE CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11096:SF1">
        <property type="entry name" value="RNA 3'-TERMINAL PHOSPHATE CYCLASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01137">
        <property type="entry name" value="RTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05189">
        <property type="entry name" value="RTC_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="EPT/RTPC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA 3'-terminal phosphate cyclase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="RNA 3'-terminal phosphate cyclase insert" evidence="2">
        <location>
            <begin position="204"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="466" mass="53931" checksum="DC95716DE4175BCD" modified="2017-02-15" version="1">MEFNGSNYFRFRLALSLISGKAITIKNIRKNKNGIKNDKELNEVNKKLEIEGLREYEAKILKLIDKLCDNTIIKINENGDELYFKPGFLIGNVNDEVRINDLNITFHCGKERSITYFLEFLLMIVPFFKNPVKLLLKGITDDSIDSTVYTLKIVSEHFFKTFLKVDENFLNITILKRGIKSDFSGEVSFFMNNLKSVNPFDISDPGLIKKIRGSIFCNKISLIFRNKFMNCAKKNLFQFTPYVNIEIEKAKFQKSDEENHFISLSLFAHTQNNCIYATDLCIDEFLLQHVKDTLNINNKRSNTDSISHGIINGNSIQNYENKLECKKIEENFLINNNDPSSKEENSCIDYNNFSNGITHNFHQVDIYERLGFFISLKMINEIKGLSSIDTNYQWLPILYMALANDTSVSKITLNILKPYSIVLIRLLSDFFSVAFDIKKVEKSQIDYSYIIKCVGVGYRNFSKKTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR41</accession>
    <name>A0A1J1GR41_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00121300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526328.1">
        <property type="nucleotide sequence ID" value="XM_028674726.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR41"/>
    <dbReference type="GeneID" id="39729738"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00121300"/>
    <dbReference type="OrthoDB" id="378111at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="941" mass="113902" checksum="351A6D39ABA9E96F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR62</accession>
    <name>A0A1J1GR62_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00146500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526581.1">
        <property type="nucleotide sequence ID" value="XM_028675007.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR62"/>
    <dbReference type="GeneID" id="39729989"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00146500"/>
    <dbReference type="OMA" id="KIQFMPQ"/>
    <dbReference type="OrthoDB" id="372396at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="442"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="629" mass="75493" checksum="F7ABBE033143F6D8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR86</accession>
    <name>A0A1J1GR86_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00126100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526376.1">
        <property type="nucleotide sequence ID" value="XM_028674780.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729786"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00126100"/>
    <dbReference type="OMA" id="NFYMLKN"/>
    <dbReference type="OrthoDB" id="372478at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1596" mass="193798" checksum="5DDEE56EDF49410E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRD5</accession>
    <name>A0A1J1GRD5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00247200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527886.1">
        <property type="nucleotide sequence ID" value="XM_028671212.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRD5"/>
    <dbReference type="GeneID" id="39731000"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00247200"/>
    <dbReference type="OMA" id="YYGWPPL"/>
    <dbReference type="OrthoDB" id="381626at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="97" mass="11654" checksum="A1EF76AE679AC3E8" modified="2017-02-15" version="1" fragment="single">MFLPCSLNNKIIKSIKKKFVTTVNIFKNSGDFNKENKNVKNVYEDYEVLKNIKKKNTLKNSLKKFREIVQKETKRKGYNFYYGWPPLNRIKITEDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRL8</accession>
    <name>A0A1J1GRL8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00258000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527988.1">
        <property type="nucleotide sequence ID" value="XM_028671325.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRL8"/>
    <dbReference type="GeneID" id="39731108"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00258000"/>
    <dbReference type="OrthoDB" id="377593at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="138" mass="16694" checksum="E1C424CBB0C517DE" modified="2017-02-15" version="1">MMFENSEGNDKKKRKLYEDTSCYEYNKKYSNYLNPFNNNDQINNYSNFYFNENASNIYRQNNAISNFLNLNNDNIQFDKNLLINSIDIILNFINYNNLNDTVKHEILHENLLNLRFHIMSLNDDKFNQKKITEYFSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRX8</accession>
    <name>A0A1J1GRX8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GTPase, putative</fullName>
            <ecNumber evidence="2">3.6.5.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00259100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.2" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527999.1">
        <property type="nucleotide sequence ID" value="XM_028671337.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRX8"/>
    <dbReference type="GeneID" id="39731120"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00259100"/>
    <dbReference type="OMA" id="MPMIYYK"/>
    <dbReference type="OrthoDB" id="299781at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003925">
        <property type="term" value="F:G protein activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47978">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="224" mass="26252" checksum="6BB89D8C6C760EAC" modified="2017-02-15" version="1">MILLQLTVIGYLNTGKTSIINSIMNNDIVYKYTHTDMPMIYYKVHKDRHRSFCVEIEDTCLEKDINSFTNMLRKEITTKKNSLKNPIFSYFENPAIPFNKDDPYNSISYGRMAYFLVFDLTNASTFDYVKMIYLKMSSIYDKYYTLKPFISLVGNKSDLVNEDNELIRQAENFANENMVQLWLTSAHTGKNVKKLFLHTINMIYNNTNLWKYDIEESGSESSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRZ9</accession>
    <name>A0A1J1GRZ9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00179200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000021">
        <property type="protein sequence ID" value="CRG94080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526901.1">
        <property type="nucleotide sequence ID" value="XM_028670117.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRZ9"/>
    <dbReference type="GeneID" id="39730319"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00179200"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="252" mass="30604" checksum="D61CE1F6F0788871" modified="2017-02-15" version="1">MRRLILFLKITTFLLLIWMYLCFHNCFSYKTLIDKNILQIKNELKYERVLTEGDIEEKKKNYAEGFLEECSLDKEKKKKNRKNPVQYENPYDIWQRDTTPYLWEQFKKETSEMDHKWRDEKWNNEWNRISANKVKELSSIFHRSDISEEEKEKLIDCAEKEIYKLFVKFLDECKTEMRGNKTESESKNEMTDNKTESESNNEMTDNKTESESKNEMTDNKTESESKNEKGKNKIKNKKSNILKFLFKRFDNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS11</accession>
    <name>A0A1J1GS11_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Sphingomyelin synthase 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00153600</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sphingomyelin synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526648.1">
        <property type="nucleotide sequence ID" value="XM_028675081.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS11"/>
    <dbReference type="GeneID" id="39730060"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00153600"/>
    <dbReference type="OMA" id="FENPPEW"/>
    <dbReference type="OrthoDB" id="422827at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047493">
        <property type="term" value="F:ceramide cholinephosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033188">
        <property type="term" value="F:sphingomyelin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045221">
        <property type="entry name" value="Sphingomyelin_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025749">
        <property type="entry name" value="Sphingomyelin_synth-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21290:SF25">
        <property type="entry name" value="SPHINGOMYELIN SYNTHASE-RELATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21290">
        <property type="entry name" value="SPHINGOMYELIN SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14360">
        <property type="entry name" value="PAP2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="67"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="155"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="263"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="308"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="Sphingomyelin synthase-like" evidence="11">
        <location>
            <begin position="207"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG93827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="401" mass="46990" checksum="B4EAE8ADEA4D5CA4" modified="2017-02-15" version="1">MKNANVNPELNEKSEEVVTERQSNKNYKMNDIYHINIEKEMNNITISKKASLNDPNNLTKWKLFRILIIKLIFSLLYLLISLIIQGFFMIYSDSYYKRYTPPLGDRIHDLFEYPPKWASYNLSNNLIAILTVFVFFRLIIFNSVYLSIAIACRFLYMLGSFYILRGILIYVTSLPATLDTCLPLESGSFRFNLLQILKINMNLVYVCSDLIISGHSFSTTLLLMFSLYYMNNVILKIILSLFCCFIYIFIIIGFIHYTSDVLLGLFFGVFIFSFYHIMLDLSSQYYIFCTLFEVKIISNKKNVQAKPFFLRFFLARIFLKIIPFLEGLNYTLNYALNKNNDFSTFCNCENYDKERNLISFCKSSKENKISIYCSDHLFHSYAGDGTISFLSLKFVKMLKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS38</accession>
    <name>A0A1J1GS38_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA/RNA-binding protein Alba 3, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ALBA3</name>
        <name evidence="1" type="ORF">PGAL8A_00382400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526941.1">
        <property type="nucleotide sequence ID" value="XM_028670161.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS38"/>
    <dbReference type="GeneID" id="39732354"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00382400"/>
    <dbReference type="OrthoDB" id="359342at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="36" mass="4210" checksum="D521954BD4E414B4" modified="2017-02-15" version="1" fragment="single">GQIIKIQTAYFSSDRINRRIPKITIVLKRHPDFVAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS60</accession>
    <name>A0A1J1GS60_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DEAD box helicase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00009800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528142.1">
        <property type="nucleotide sequence ID" value="XM_028671495.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728620"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00009800"/>
    <dbReference type="OrthoDB" id="66977at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17917">
        <property type="entry name" value="DEXHc_RHA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF237">
        <property type="entry name" value="ATP-DEPENDENT DNA_RNA HELICASE DHX36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1093"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1195"/>
            <end position="1216"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="645"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="937"/>
            <end position="1109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1684"/>
            <end position="1707"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1772"/>
            <end position="1828"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="2066"/>
            <end position="2086"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1694"/>
            <end position="1707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1772"/>
            <end position="1800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="2074"/>
            <end position="2086"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG95331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2255" mass="269025" checksum="1D08E402B3AB1CE4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS65</accession>
    <name>A0A1J1GS65_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Heat shock protein 110, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">HSP110</name>
        <name evidence="6" type="ORF">PGAL8A_00255300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527961.1">
        <property type="nucleotide sequence ID" value="XM_028671294.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS65"/>
    <dbReference type="GeneID" id="39731081"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00255300"/>
    <dbReference type="OMA" id="SRTPMIQ"/>
    <dbReference type="OrthoDB" id="10262720at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034663">
        <property type="term" value="C:endoplasmic reticulum chaperone complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10230">
        <property type="entry name" value="ASKHA_NBD_HSP70_HYOU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000029">
        <property type="entry name" value="Heat shock protein 110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639">
        <property type="entry name" value="HSC70CB, ISOFORM G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639:SF3">
        <property type="entry name" value="HYPOXIA UP-REGULATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013017922" evidence="5">
        <location>
            <begin position="21"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="569"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="912"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="912"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="994"/>
            <end position="1005"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1005" mass="117051" checksum="11EA593CECF45C22" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS96</accession>
    <name>A0A1J1GS96_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Serine/threonine protein kinase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ARK3</name>
        <name evidence="14" type="ORF">PGAL8A_00163200</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526744.1">
        <property type="nucleotide sequence ID" value="XM_028675187.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730157"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00163200"/>
    <dbReference type="OMA" id="NKKGIDD"/>
    <dbReference type="OrthoDB" id="377346at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030616">
        <property type="entry name" value="Aur-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24350">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE IAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 8 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 14" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="1177"/>
            <end position="1429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="2807"/>
            <end position="2829"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="3138"/>
            <end position="3168"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="3060"/>
            <end position="3097"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="3586"/>
            <end position="3620"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="1302"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="1206"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="1207"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="1306"/>
            <end position="1307"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="1320"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="cross-link" description="Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)" evidence="9">
        <location>
            <position position="1304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG93923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3916" mass="459401" checksum="C0EB70E1A946C8B9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSC8</accession>
    <name>A0A1J1GSC8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-directed RNA polymerase II 16 kDa subunit, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00018800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the eukaryotic RPB4 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528230.1">
        <property type="nucleotide sequence ID" value="XM_028671593.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSC8"/>
    <dbReference type="GeneID" id="39728710"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00018800"/>
    <dbReference type="OMA" id="PEFKNCK"/>
    <dbReference type="OrthoDB" id="2186918at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006590">
        <property type="entry name" value="RNA_pol_Rpb4/RPC9_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045222">
        <property type="entry name" value="Rpb4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005574">
        <property type="entry name" value="Rpb4/RPC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038324">
        <property type="entry name" value="Rpb4/RPC9_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21297">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03874">
        <property type="entry name" value="RNA_pol_Rpb4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00657">
        <property type="entry name" value="RPOL4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="HRDC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RNA polymerase Rpb4/RPC9 core" evidence="4">
        <location>
            <begin position="16"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="132" mass="15194" checksum="9438FF40213DF35F" modified="2017-02-15" version="1">MANNMQGDIKNLDLGPEFKNCKCLNLCELQLILGDQLRLTSKRNEEAQALIKSSFDYANKFATIKNRSSIVDIRTNLERIGDLHEYEIAMLVNLLPKTILEARYFIPSLIRLNDDTLNSILEHLISYKMYVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSJ5</accession>
    <name>A0A1J1GSJ5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Zinc finger protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00017300</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528215.1">
        <property type="nucleotide sequence ID" value="XM_028671576.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSJ5"/>
    <dbReference type="GeneID" id="39728695"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00017300"/>
    <dbReference type="OMA" id="NILLIWN"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000151">
        <property type="term" value="C:ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15067">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15067:SF4">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="289"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG95404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="780" mass="94829" checksum="9E1BD05164C5D976" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSM7</accession>
    <name>A0A1J1GSM7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Palmitoyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">DHHC12</name>
        <name evidence="9" type="ORF">PGAL8A_00021400</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528255.1">
        <property type="nucleotide sequence ID" value="XM_028671620.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSM7"/>
    <dbReference type="GeneID" id="39728736"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00021400"/>
    <dbReference type="OMA" id="YRIPYIR"/>
    <dbReference type="OrthoDB" id="5977743at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883:SF483">
        <property type="entry name" value="PALMITOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883">
        <property type="entry name" value="ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="8">
        <location>
            <begin position="102"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG95444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="287" mass="34355" checksum="AFA6946C412D1544" modified="2017-02-15" version="1">MNTLKSYMNLIFLKANHYFQFYYSFSMYVKIKKKIIFEIEKETYFILERYYNTSCNSFFCMLIFISGFSSFLLCSLSDPGKISSKYLDKHLKFYPYDGIIFHKDSECETCKIKKPARSKHCKYCSSCISRYDHHCFLLNNCIGGYNNVYFIIFICVNIIITFYSSYISLYSVIKYENLLEATFINHKTNEILPNSYLTIVNYLFSEYSATFSLFIISISTFFCILLFFLHEIYLNFYVNMTNNEKAKYNKLKNSNLHRNKNFYSFIRNVNDALFYKKNIENFPKKFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSP1</accession>
    <name>A0A1J1GSP1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GRIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00004500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528091.1">
        <property type="nucleotide sequence ID" value="XM_028671439.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728567"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00004500"/>
    <dbReference type="OMA" id="CERNITY"/>
    <dbReference type="OrthoDB" id="385258at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000237">
        <property type="entry name" value="GRIP_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50913">
        <property type="entry name" value="GRIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GRIP" evidence="3">
        <location>
            <begin position="1724"/>
            <end position="1775"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="389"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="638"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="868"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="762"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1229"/>
            <end position="1302"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1341"/>
            <end position="1389"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1450"/>
            <end position="1630"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1697"/>
            <end position="1724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="638"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="654"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="868"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1025"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1052"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1064"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1076"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1088"/>
            <end position="1120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1139"/>
            <end position="1150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1779" mass="209447" checksum="33235C252ABCDAEC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSV5</accession>
    <name>A0A1J1GSV5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cytochrome c, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00275900</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="10">Binds 1 heme group per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome c family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528370.1">
        <property type="nucleotide sequence ID" value="XM_028671748.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSV5"/>
    <dbReference type="GeneID" id="39731291"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00275900"/>
    <dbReference type="OMA" id="KARCAQC"/>
    <dbReference type="OrthoDB" id="449280at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.760.10:FF:000001">
        <property type="entry name" value="Cytochrome c iso-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="entry name" value="Cytochrome c-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002327">
        <property type="entry name" value="Cyt_c_1A/1B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11961">
        <property type="entry name" value="CYTOCHROME C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00604">
        <property type="entry name" value="CYTCHRMECIAB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="Cytochrome c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4 8 10" id="KW-0349">Heme</keyword>
    <keyword evidence="7 8 10" id="KW-0408">Iron</keyword>
    <keyword evidence="5 8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cytochrome c" evidence="11">
        <location>
            <begin position="15"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG95561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="117" mass="13054" checksum="1622A426450800A0" modified="2017-02-15" version="1">MSQIRSEPQVEVPAGDYKKGAKIFKAKCAQCHTINKGGAVKQGPNLHGFYGRKSGESDFPYSDANKNSGIIWSDKHLFEYLLNPKLYIPGTKMVFAGIKKEKERADLVEYLKKASSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT06</accession>
    <name>A0A1J1GT06_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00283300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528444.1">
        <property type="nucleotide sequence ID" value="XM_028671830.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT06"/>
    <dbReference type="GeneID" id="39731366"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00283300"/>
    <dbReference type="OMA" id="VNRNPFR"/>
    <dbReference type="OrthoDB" id="514248at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010286">
        <property type="entry name" value="METTL16/RlmF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13393:SF0">
        <property type="entry name" value="RNA N6-ADENOSINE-METHYLTRANSFERASE METTL16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13393">
        <property type="entry name" value="SAM-DEPENDENT METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05971">
        <property type="entry name" value="Methyltransf_10"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="157"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="592" mass="70938" checksum="D24B4A9E654E1EA2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT33</accession>
    <name>A0A1J1GT33_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein RER1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RER1</name>
        <name evidence="8" type="ORF">PGAL8A_00184800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the RER1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000024">
        <property type="protein sequence ID" value="CRG94456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527277.1">
        <property type="nucleotide sequence ID" value="XM_028670535.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT33"/>
    <dbReference type="GeneID" id="39730375"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00184800"/>
    <dbReference type="OMA" id="GWYVVCY"/>
    <dbReference type="OrthoDB" id="448250at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006621">
        <property type="term" value="P:protein retention in ER lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004932">
        <property type="entry name" value="Rer1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10743">
        <property type="entry name" value="PROTEIN RER1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10743:SF0">
        <property type="entry name" value="PROTEIN RER1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03248">
        <property type="entry name" value="Rer1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016013">
        <property type="entry name" value="AtER_Rer1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="34"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="126"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR016013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="201" mass="24220" checksum="D474C682A9584F0E" modified="2017-02-15" version="1">MEEGENFLPNIYDKLINTHNYYIDKTTLYLKTRWFLLLILLILYIVRVYYVTGFYVVSYALSIFLLNLFLRFLTPHNIEEIYEQYENENNGLLLPMKQTNETKNENNSDDKKEFRPFLRKLNEFKFWLHSTRAVLISIICTFFPFLDIPVFWPLLLFYFICLFLATMKQQIKNMIKFKYLPFNTSTKQTYGSIARGSKITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTA0</accession>
    <name>A0A1J1GTA0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00265900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000035">
        <property type="protein sequence ID" value="CRG95456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528267.1">
        <property type="nucleotide sequence ID" value="XM_028671634.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTA0"/>
    <dbReference type="GeneID" id="39731188"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00265900"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="295"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="333" mass="38771" checksum="65DBA3FA783E50CB" modified="2017-02-15" version="1">MALLYNKGCKKSNNNLSNCDMHLCPIYGGIYQTIHCSPAFIPADVRYLPSDLSKNEFLLENFNSEGDNYKVTVLSENESENIVFLLEYISDNLLYFRRVYLCRLKTLEQKVTLCALVNDDLLENTITFNSFDVIDRKNERSLVKLKSLKNPKHETLMLDYKDIYFSKDACYVTELGLGSLYDYVCRYSICEKHHKDHMTCKDAKFNGKVIHLGNHSIINQDKEQVIYLPDSCLKHKLKFECTPYFCEYSNMNELKQCKGLEISAVKNVIPKHEGRDITGTNSKYMIHKSNKDMSILAASFIPFLILVIFIACYIYRAYRRNRKRGLKKRDKEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTC6</accession>
    <name>A0A1J1GTC6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sporozoite invasion-associated protein 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SIAP2</name>
        <name evidence="3" type="ORF">PGAL8A_00268400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000037">
        <property type="protein sequence ID" value="CRG95482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528291.1">
        <property type="nucleotide sequence ID" value="XM_028671661.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTC6"/>
    <dbReference type="GeneID" id="39731214"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00268400"/>
    <dbReference type="OMA" id="ICLTFSQ"/>
    <dbReference type="OrthoDB" id="387469at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013312129" evidence="2">
        <location>
            <begin position="25"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="387" mass="44442" checksum="857E27BC74B048F2" modified="2017-02-15" version="1">MGMSKIFLFFHLILFINLLKKCLSSERKGLRHSMKVLSSPENLGDTLSNTSQEELSDNCNSEQDKNLESNNKCIRSEPSCLQDNMSELMDKSDDSKEDFEELNSNEDSKSYDAMCLEDFCYSSCESLNELIDENNKSQRCYRKKLEISEKSYNNDSSTSSNKEYPSWDPLQSLLEEMGYSHDEEKTKVKIKESENDDASYCSFLDESDNLENKHENTHTLSNPLKSISDNARKLLSKNVSCDSDSSSYSDPNKISSENVKEMGELSDAFGNFNPLCDYTSFLKSHGLSDSTLKEPKGDPEPFSLDCNYFRIVDSNNFKFFILKNLYENFKILDIKDKIKLLINIIDIYNFIKKLARINFVCLTYKEEEEAAVDGAFLLDLVLKKEME</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTD2</accession>
    <name>A0A1J1GTD2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PIR-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00195300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527373.1">
        <property type="nucleotide sequence ID" value="XM_028670640.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTD2"/>
    <dbReference type="GeneID" id="39730480"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00195300"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="395" mass="42764" checksum="E61AB5ADE23D4255" modified="2017-02-15" version="1">MNGQNSTESYAWNTTNNLTTRLLTEMSTEVPSLSTLESTSQANTTLSSLTESLGSLVSSAQTSSSSLLSQVTTHLSNLTSSNTTSPSSTLESATHILTSGVAENATSSPTTTSFLSEAKNFTDYLSSTISSTISEALTPNSTSPNSTLESATHSLTSRVTEGATSSATTSVLTEQASKFTNYLSTTIKENISQALTSNTTLSDLTTSNLGNTLTTQATTPLYDTSTINNTSSSLFSFNGTTLNNLVTTANNTTQILGGNDSDGVVKEMNVTPVIIFFITLCILGFLAWANLGAHVKKDNPECCSRKNKLDDIEMKPIKKEDSNDKEDNLDDGDENKEGKKGKRRKKKDDNPDIQQRLIQELTEEQETLRTGKRIRKKKTENNDEKFCEVRIEDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTF4</accession>
    <name>A0A1J1GTF4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transcription factor with AP2 domain(S), putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ApiAP2</name>
        <name evidence="8" type="ORF">PGAL8A_00300800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528604.1">
        <property type="nucleotide sequence ID" value="XM_028672008.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTF4"/>
    <dbReference type="GeneID" id="39731541"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00300800"/>
    <dbReference type="OrthoDB" id="364262at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028078">
        <property type="entry name" value="ACDC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14733">
        <property type="entry name" value="ACDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00847">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="6">
        <location>
            <begin position="52"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="AP2-coincident C-terminal" evidence="7">
        <location>
            <begin position="631"/>
            <end position="716"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="733" mass="86019" checksum="12D92108B43FE2EF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTR1</accession>
    <name>A0A1J1GTR1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">N-acetyltransferase, putative</fullName>
            <ecNumber evidence="5">2.3.1.48</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00308600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528682.1">
        <property type="nucleotide sequence ID" value="XM_028672095.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTR1"/>
    <dbReference type="GeneID" id="39731619"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00308600"/>
    <dbReference type="OMA" id="HDHFNSL"/>
    <dbReference type="OrthoDB" id="41532at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061733">
        <property type="term" value="F:protein-lysine-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050769">
        <property type="entry name" value="NAT_camello-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13947">
        <property type="entry name" value="GNAT FAMILY N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13947:SF37">
        <property type="entry name" value="LD18367P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="88"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="4">
        <location>
            <begin position="481"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="220"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="405"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="411"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="645" mass="75640" checksum="C01A9CA30CCE7E1F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTT7</accession>
    <name>A0A1J1GTT7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Tat binding protein 1(TBP-1)-interacting protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00315500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528750.1">
        <property type="nucleotide sequence ID" value="XM_028672170.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTT7"/>
    <dbReference type="GeneID" id="39731688"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00315500"/>
    <dbReference type="OMA" id="RERETCI"/>
    <dbReference type="OrthoDB" id="272266at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000794">
        <property type="term" value="C:condensed nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120231">
        <property type="term" value="C:DNA recombinase auxiliary factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120230">
        <property type="term" value="F:recombinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007129">
        <property type="term" value="P:homologous chromosome pairing at meiosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000709">
        <property type="term" value="P:meiotic joint molecule formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010774">
        <property type="term" value="P:meiotic strand invasion involved in reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010776">
        <property type="entry name" value="Hop2_WH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15938:SF0">
        <property type="entry name" value="HOMOLOGOUS-PAIRING PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15938">
        <property type="entry name" value="TBP-1 INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07106">
        <property type="entry name" value="WHD_TBPIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-0469">Meiosis</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homologous-pairing protein 2 winged helix" evidence="7">
        <location>
            <begin position="900"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="60"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="134"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="994"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="8"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="60"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="82"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="101"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="166"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="204"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="333"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="347"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="363"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="530"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="540"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="550"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="655"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="677"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="728"/>
            <end position="737"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1103" mass="131178" checksum="35BB30B48B29E99F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU22</accession>
    <name>A0A1J1GU22_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fam-b protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00221100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527629.1">
        <property type="nucleotide sequence ID" value="XM_028670925.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU22"/>
    <dbReference type="GeneID" id="39730738"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00221100"/>
    <dbReference type="OrthoDB" id="391976at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012453008" description="Fam-b protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="130" mass="15649" checksum="A5F3FB8CB8C23FBF" modified="2017-02-15" version="1">MNTAKLFCLFFLLMLINVIKDTKCSDEKEKFSQNISFLQSKIKNGEKNMPGIFDLFSVKPNSAQPNFNFFLEENRNFWLRRTLNDEKNRNIRRNFADFQELRQNDLLRFEELMIIQNEQINIIKNIIYSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU27</accession>
    <name>A0A1J1GU27_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytidine deaminase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00317200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytidine and deoxycytidylate deaminase family. ADAT3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528767.1">
        <property type="nucleotide sequence ID" value="XM_028672189.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU27"/>
    <dbReference type="GeneID" id="39731705"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00317200"/>
    <dbReference type="OMA" id="FMCAMAM"/>
    <dbReference type="OrthoDB" id="3180714at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052717">
        <property type="term" value="F:tRNA-specific adenosine-34 deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079">
        <property type="entry name" value="CYTOSINE DEAMINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079:SF156">
        <property type="entry name" value="INACTIVE TRNA-SPECIFIC ADENOSINE DEAMINASE-LIKE PROTEIN 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="354" mass="41523" checksum="6D474A23222E2C36" modified="2017-02-15" version="1">MENDIIGLEQIFPDAYIQNITLISMYCFELKKSLADEALNIMKNFINTQLHDNYNHLKRCKKTNDNVQILIGFCKNIPSELYKELTDINKGDIEIKEVKVSRYPPMTKKQYSEWSKFWPLYYRKPAYDLSTLTKEQIKKYINFIKISIDVGKNFGTCQSGCILTYNDKIVASSGDNIKNHPLQHSVMLAIEEASYKLRHLLQIKKMISIRNCEHNNKINNYLSKSCIQPLTYENSKLKDFKEQNNNNNVKKSTVVKEENCKCDEKMLKDDDKNLNLNIYKPIKINQYLCTNYFAYLSHEPCFMCAMAMVHSRIKCVIFDKVNKENGALFSKEKLHCLKNLNHHFKVFKTIRKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUP7</accession>
    <name>A0A1J1GUP7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dynein axonemal assembly factor 5 TPR repeats domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00339600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528983.1">
        <property type="nucleotide sequence ID" value="XM_028672430.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUP7"/>
    <dbReference type="GeneID" id="39731926"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00339600"/>
    <dbReference type="OMA" id="DCIEVWN"/>
    <dbReference type="OrthoDB" id="413572at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052623">
        <property type="entry name" value="DAAF5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057978">
        <property type="entry name" value="TPR_DAAF5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16216">
        <property type="entry name" value="DYNEIN ASSEMBLY FACTOR 5, AXONEMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16216:SF2">
        <property type="entry name" value="DYNEIN AXONEMAL ASSEMBLY FACTOR 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25757">
        <property type="entry name" value="TPR_DNAAF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynein axonemal assembly factor 5 TPR repeats" evidence="2">
        <location>
            <begin position="32"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="641"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="648"/>
            <end position="675"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1112" mass="133066" checksum="61017F69B9D5C9F6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUU4</accession>
    <name>A0A1J1GUU4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00322400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000049">
        <property type="protein sequence ID" value="CRG96011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528819.1">
        <property type="nucleotide sequence ID" value="XM_028672248.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUU4"/>
    <dbReference type="GeneID" id="39731757"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00322400"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="278" mass="33648" checksum="A9440FC291AF4A89" modified="2017-02-15" version="1">MKTLTLNLKITTFLLLIWMYQYFYNCDSYKILIDKYILQTKNELKYERILTEGDIAGKMQTYSEGCIEEYSLDDKKNKWENLLLQQNPYDRWQKVTNPSLLERFKKETCGMDPKWIDEKWNNEWNNISANKVNELSSIFDRSDISEEEKGKLIRSVMKELYRLYFNFIGECKKEMSENKTESESKIGMSYNKTESESWKEMRENKTESECMKEMRDNKTEFKSMKDVIDNKKESESESEKEMRENKEEYKYKNEQGKNKKKKKKSNILKFLFCRCDNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV37</accession>
    <name>A0A1J1GV37_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Casein kinase I</fullName>
            <ecNumber evidence="5">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="primary">CK1</name>
        <name evidence="23" type="ORF">PGAL8A_00364100</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="19">Cytoplasmic vesicle</location>
            <location evidence="19">Secretory vesicle</location>
            <location evidence="19">Microneme</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Host cell surface</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529222.1">
        <property type="nucleotide sequence ID" value="XM_028672695.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV37"/>
    <dbReference type="SMR" id="A0A1J1GV37"/>
    <dbReference type="GeneID" id="39732171"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00364100"/>
    <dbReference type="OMA" id="IFDWTFL"/>
    <dbReference type="OrthoDB" id="5800476at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044228">
        <property type="term" value="C:host cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020009">
        <property type="term" value="C:microneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14125">
        <property type="entry name" value="STKc_CK1_delta_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000538">
        <property type="entry name" value="Casein kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050235">
        <property type="entry name" value="CK1_Ser-Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11909">
        <property type="entry name" value="CASEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 20 21" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="15" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="12 23" id="KW-0418">Kinase</keyword>
    <keyword evidence="14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 20 21" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0964">Secreted</keyword>
    <keyword evidence="8 21" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="9 23" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="22">
        <location>
            <begin position="9"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00060412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="CRG96417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="323" mass="37631" checksum="9E158DAB0C1BA543" modified="2017-02-15" version="1">MEIRVANKYALGKKLGSGSFGDIYVAKDIVTMEEFAVKLESTRSKHPQLLYESKLYKILGGGIGVPKVYWYGIEGDFTIMVLDLLGPSLEDLFTLCNRKFSLKTVLMTADQMLNRIEYVHSKNFIHRDIKPDNFLIGRGKKVTLIHIIDFGLAKKYRDSRSHTHIPYKEGKNLTGTARYASINTHLGIEQSRRDDIEALGYVLMYFLRGSLPWQGLKAISKKDKYDKIMEKKISTSVEVLCRNASFEFVTYLNYCRSLRFEDRPDYTYLRRLLKDLFIREGFTYDFLFDWTCVYASEKDKKKMLENKNRFDQTADQEGRVKQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV77</accession>
    <name>A0A1J1GV77_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00365600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529236.1">
        <property type="nucleotide sequence ID" value="XM_028672711.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV77"/>
    <dbReference type="GeneID" id="39732186"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00365600"/>
    <dbReference type="OMA" id="NKSHTCK"/>
    <dbReference type="OrthoDB" id="371003at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="466"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="592"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="720" mass="87708" checksum="825A645D77335056" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV84</accession>
    <name>A0A1J1GV84_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00261300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528021.1">
        <property type="nucleotide sequence ID" value="XM_028671361.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV84"/>
    <dbReference type="GeneID" id="39731142"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00261300"/>
    <dbReference type="OrthoDB" id="378922at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027973">
        <property type="entry name" value="FSAF1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15375">
        <property type="entry name" value="FSAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="277" mass="33586" checksum="D319068FC2C6FA2A" modified="2017-02-15" version="1">MKKLKEKTSNNEIKLQKYMDKIWGFSDDEKRLLNEKSKKKDKIKKNTYAENKKLNIDDEKKIISDLKNKEQNDNLINKVMLKKDNNQLNSINMDEKKKKENQKKVKSKNHLNVTNNVNEKMSVLNNIQKKENIEIHSSDRRLKEKNNNIKKRFEKKNHNKFDESKKKEIYKEKMKLKKDFMETVHEIRKISLPFLNKFQKKIVENHQIKTLGGKFDKSRKIHYPELMCRKKSMKKYISKRKEKEKILGVKIQSGNYIDMQDVFRKKRKEKKIQRKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV86</accession>
    <name>A0A1J1GV86_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00335700</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha chain contains the catalytic site.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528947.1">
        <property type="nucleotide sequence ID" value="XM_028672390.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV86"/>
    <dbReference type="GeneID" id="39731887"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00335700"/>
    <dbReference type="OMA" id="ECHMIEW"/>
    <dbReference type="OrthoDB" id="10254671at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005956">
        <property type="term" value="C:protein kinase CK2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14132">
        <property type="entry name" value="STKc_CK2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000059">
        <property type="entry name" value="Casein kinase II subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000088">
        <property type="entry name" value="Casein kinase II subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045216">
        <property type="entry name" value="CK2_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24054">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24054:SF0">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="43"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00059329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG96142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="335" mass="39971" checksum="962ED51B198618E1" modified="2017-02-15" version="1">MSVSSINKRIYIPKFYADVNIHKPKEYYDYDNLELQWNKPNRYEIMKKIGRGKYSEVFNGYDTEYNRPCAIKVLKPVKKKKIKREIKILQNLHGGPNIIKLLDIVKDPVTKTPSLIFEYINNIDFKTLYPKFTDKDIRYYIYQILKALDYCHSQGIMHRDVKPHNIMIDHENKQIRLIDWGLAEFYHPGQEYNVRVASRYYKGPELLIDLQLYDYSLDIWSLGCMLAGMIFKKEPFFCGHDNYDQLVKIAKVLGTDDLHAYLKKYNIKLKPHYLNILGEYERKPWSHFLTQSNIDIAKDEVIDLIDKMLVYDHAKRIAPKEAMEHPYFREVREEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVC6</accession>
    <name>A0A1J1GVC6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00370400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529284.1">
        <property type="nucleotide sequence ID" value="XM_028672764.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVC6"/>
    <dbReference type="GeneID" id="39732234"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00370400"/>
    <dbReference type="OMA" id="VYNYLYY"/>
    <dbReference type="OrthoDB" id="377068at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="825" mass="98101" checksum="458E61B3128B609A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVD2</accession>
    <name>A0A1J1GVD2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">P-loop containing nucleoside triphosphate, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00367800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529258.1">
        <property type="nucleotide sequence ID" value="XM_028672735.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVD2"/>
    <dbReference type="GeneID" id="39732208"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00367800"/>
    <dbReference type="OMA" id="VCIYGRE"/>
    <dbReference type="OrthoDB" id="420422at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033063">
        <property type="term" value="C:Rad51B-Rad51C-Rad51D-XRCC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005657">
        <property type="term" value="C:replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030547">
        <property type="entry name" value="XRCC2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46644">
        <property type="entry name" value="DNA REPAIR PROTEIN XRCC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46644:SF2">
        <property type="entry name" value="DNA REPAIR PROTEIN XRCC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="362" mass="42683" checksum="A52E1295F9E4716A" modified="2017-02-15" version="1">MANKKTENFEIDCTCLELYERVTKKYCFNDCAIIKKCIKNGILKESDSVCIYGKENCGKTLLLTEILVDLTAVKELKGMNCKVVYLDCDLSFNYKNYENIINNKFLKYMSNYKTINTDKCKNNSLKKELLDNSFSNIYYIPIFNPGHLLVILNTLKILLEKKISIEALIIDSLSFWNFCKYDKINFFSDNNYVKRNASDLLDYAFTLILNLKKKFKFLFIYTKLSNEDKFIEYTINLSFNEKLKEQINGVEIPENKNYHNFSINKSNDLKQVFLIPHNFNDILKTHIFRKKDFITNNFLIEKPFLIFLISNEKSEFTPINKKNDLKNLNILLCLSSEMKDMDKIHYSKFFFMIINSHTIVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVF5</accession>
    <name>A0A1J1GVF5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00242500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527840.1">
        <property type="nucleotide sequence ID" value="XM_028671160.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVF5"/>
    <dbReference type="GeneID" id="39730953"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00242500"/>
    <dbReference type="OMA" id="DYISTIH"/>
    <dbReference type="OrthoDB" id="369837at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="214" mass="26082" checksum="14358A35AC93C838" modified="2017-02-15" version="1">MNNFLAKIIFLIYIICIANVSIIKIAITDCKKLKKINYKNYYKNHYKYNYNNKKNIFLRIKNPFFSIQKLKTNRNLHSFINIKSWKEDLKHFLHKYGIYNNQNIHPLKNCLWEITIYNFFLQKQKSFFIYIFEDGNLKTSENLYGKWSYNNYYITWYIEEKNKKVYYTAELLWNYENSKMVKGIIYEEKKKTSSFLPSSIFRKIIGSFEGKINS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW29</accession>
    <name>A0A1J1GW29_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00425000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529474.1">
        <property type="nucleotide sequence ID" value="XM_028672974.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW29"/>
    <dbReference type="GeneID" id="39732782"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00425000"/>
    <dbReference type="OrthoDB" id="371940at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="292"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="330"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="383"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="432" mass="51545" checksum="EAECB7FDE5FCD334" modified="2017-02-15" version="1">MTRKYFKKIIIISSFMILLVNLRIVYNFEESFFNNNFNLFKYFNSYHIKIDDLKINENYLFKKPDNINIELALSALKGIKYDNDNKNIIEGKKNIEISKWNKLTKKDFFNENKEEENLIKGMPEPYYIYNITDNIKNTKFYFNNNNIENMEIIYKGKYIPKIYNNIFLIFAISFMYLFCIKILLQGYINGKNTAKKFISKISTLFTFFIILKIMLSLIPPFLCASLCIIVTFYFFSISMNPCENFFFLKNSKIKKEPIGWILIVFSQSILIGNFIYHLLFNVKVLNMLISHVHYYFLLHFICFVVLLLIASLIFFFMISNIFSAKKAQNFVFSFTSSYLIVSCYTYFYNLFILRFLNNTNIVQIEPIMFFSYTPKFVFNKQNMVALLILFMMTIMSLVLPKWLKQSNPLSKKIKQTDKKITNKYDVFLNYFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW68</accession>
    <name>A0A1J1GW68_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00274600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528357.1">
        <property type="nucleotide sequence ID" value="XM_028671734.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731278"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00274600"/>
    <dbReference type="OMA" id="REGFCKF"/>
    <dbReference type="OrthoDB" id="378531at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="304"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="337"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="486"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="761"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="798"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="890"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1202"/>
            <end position="1229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="304"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="347"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="486"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="556"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="599"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="617"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="761"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="802"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="907"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="917"/>
            <end position="1016"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1392" mass="167271" checksum="05C403511CD779CF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW78</accession>
    <name>A0A1J1GW78_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein YIPF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00374300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Golgi apparatus membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the YIP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529323.1">
        <property type="nucleotide sequence ID" value="XM_028672807.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW78"/>
    <dbReference type="GeneID" id="39732273"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00374300"/>
    <dbReference type="OMA" id="IKFYHVL"/>
    <dbReference type="OrthoDB" id="411251at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045231">
        <property type="entry name" value="Yip1/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006977">
        <property type="entry name" value="Yip1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21236">
        <property type="entry name" value="GOLGI MEMBRANE PROTEIN YIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21236:SF1">
        <property type="entry name" value="PROTEIN YIPF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04893">
        <property type="entry name" value="Yip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="Yip1" evidence="7">
        <location>
            <begin position="49"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="186" mass="21949" checksum="B3783350D62B0E77" modified="2017-02-15" version="1">MDTNAPRLDNYEFTMDEPVKDTLIRDVKSIFKKILYICFHQYDDSNTIKKWDLWGSFIVYITLSIIIFLDEEVIDKKNTFAYFFVFFIIGHILVSLNLSLLHINIQFFQSLCIISYSLFPLVFSSFLNLFISSPALRFLFSFFSIVWSSYNCILILAKFIKKNRLLISLFPICLLHVFIATFLLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW99</accession>
    <name>A0A1J1GW99_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00277800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528389.1">
        <property type="nucleotide sequence ID" value="XM_028671770.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731311"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00277800"/>
    <dbReference type="OMA" id="KMKLFFC"/>
    <dbReference type="OrthoDB" id="390313at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1969"/>
            <end position="1996"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="424"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1970"/>
            <end position="1990"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2455" mass="299282" checksum="17870603B5C9AA76" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWF7</accession>
    <name>A0A1J1GWF7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">DNA 5'-3' helicase</fullName>
            <ecNumber evidence="17">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="primary">XPD</name>
        <name evidence="22" type="ORF">PGAL8A_00447200</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the helicase family. RAD3/XPD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="17"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529694.1">
        <property type="nucleotide sequence ID" value="XM_028673219.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWF7"/>
    <dbReference type="GeneID" id="39733005"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00447200"/>
    <dbReference type="OMA" id="WQTMGIL"/>
    <dbReference type="OrthoDB" id="272481at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045951">
        <property type="term" value="P:positive regulation of mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18788">
        <property type="entry name" value="SF2_C_XPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000135">
        <property type="entry name" value="DNA repair helicase RAD3, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000128">
        <property type="entry name" value="Putative DNA repair helicase RAD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010643">
        <property type="entry name" value="HBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006554">
        <property type="entry name" value="Helicase-like_DEXD_c2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010614">
        <property type="entry name" value="RAD3-like_helicase_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013020">
        <property type="entry name" value="Rad3/Chl1-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00604">
        <property type="entry name" value="rad3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472:SF1">
        <property type="entry name" value="GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06733">
        <property type="entry name" value="DEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06777">
        <property type="entry name" value="HBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00488">
        <property type="entry name" value="DEXDc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="19" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 22" id="KW-0347">Helicase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="15" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="21">
        <location>
            <begin position="8"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="411"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="19">
        <location>
            <begin position="97"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00048954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="CRG96891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1045" mass="121818" checksum="B169922B24065CD6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX88</accession>
    <name>A0A1J1GX88_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00449900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000076">
        <property type="protein sequence ID" value="CRG96918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529721.1">
        <property type="nucleotide sequence ID" value="XM_028673249.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX88"/>
    <dbReference type="GeneID" id="39733032"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00449900"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="229" mass="27901" checksum="7B7500375C7C90AE" modified="2017-02-15" version="1">MKTLTLYLKITTFLLLIWMYQCFYNCYSYKTLIDKNILQIKNELKYERVLTEGDIAGNKQTNAEECLEECPLDNEKNKCIDPDLYKNPHHYWRKVMIPKLWERFNKETSEMDPKSKNRKWNVHWYNISTTKVRELYSMSRRRDIPDEEKNEKIDSIMKEIDSEFDKFLYECKKEMTDNKTEYESNKDIIENITESESKKEQGKNEIKNNKLKIWKLFINCFYNPDENKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX89</accession>
    <name>A0A1J1GX89_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phospholipid or glycerol acyltransferase, putative</fullName>
            <ecNumber evidence="2">2.3.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00474800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000093">
        <property type="protein sequence ID" value="CRG97169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529972.1">
        <property type="nucleotide sequence ID" value="XM_028673528.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX89"/>
    <dbReference type="GeneID" id="39733281"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00474800"/>
    <dbReference type="OrthoDB" id="10444667at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="133" mass="16015" checksum="28B8E1E3AEE30334" modified="2017-02-15" version="1">MIRKFEYHIVSHILFGLHVKLFMNKIFSKKWIWDFFHFYFCMVIIYLTILIIYATRVHYNLKKLDLKYFPVESISSCKNYVNRKNIHPFAAFERNDLIHMKYINLLYGVIFVATWKLLAAFILSVTNLSFCGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXC2</accession>
    <name>A0A1J1GXC2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">rRNA adenine N(6)-methyltransferase</fullName>
            <ecNumber evidence="7">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00470800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529930.1">
        <property type="nucleotide sequence ID" value="XM_028673482.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXC2"/>
    <dbReference type="GeneID" id="39733241"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00470800"/>
    <dbReference type="OMA" id="QTKVWRK"/>
    <dbReference type="OrthoDB" id="74991at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000179">
        <property type="term" value="F:rRNA (adenine-N6,N6-)-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.100">
        <property type="entry name" value="Ribosomal RNA adenine dimethylase-like, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00607">
        <property type="entry name" value="16SrRNA_methyltr_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023165">
        <property type="entry name" value="rRNA_Ade_diMease-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020596">
        <property type="entry name" value="rRNA_Ade_Mease_Trfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011530">
        <property type="entry name" value="rRNA_adenine_dimethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00755">
        <property type="entry name" value="ksgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="DIMETHYLADENOSINE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727:SF18">
        <property type="entry name" value="RRNA ADENINE N(6)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01131">
        <property type="entry name" value="RRNA_A_DIMETH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51689">
        <property type="entry name" value="SAM_RNA_A_N6_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 7" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4 6 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6 7" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013017918" description="rRNA adenine N(6)-methyltransferase" evidence="8">
        <location>
            <begin position="23"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal RNA adenine methylase transferase N-terminal" evidence="9">
        <location>
            <begin position="145"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG97127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="452" mass="53575" checksum="3F9F17567AE94018" modified="2017-02-15" version="1">MNKTLTKFIYMFLLLLFVKIKCHFLKEINNVALLDSKYFYIKLRRRNNRNVLHFCFIENNIKRNIKKKKICKKKLILLSDYVTNEDGKSYNESTKNKYISQTFEGISIYPLKQEDKENPLRTKIPANEFKPKRSLGQNYLKDENIIRKMVDAVELDINDYFFFKNSKVNVEKKNEQNCKKEKNENEKNSECESFEKHNFESIKNKGKGIIELGCGLGQISKFLFRKYPNMTGIEIDSRALSIISRTMPGFDFIHDDVLQVNYRELSLNKKTKLTVIGNLPFYITSQILFCLLDFYKYIEQAIVTIQYEVGQRIVAKPNNKNYSILSILFSLYSKPYLLFKIPSKAFYPVPKVEAAVMKIIFKKEDFNCNLLFLKQILRYAFQQRRKKLKSSLKPLLNQYNINQIPQSFIDLRPQQLLPCQFIELTNILFPLNIYPFDQNIQTKVWRKKKHGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXH0</accession>
    <name>A0A1J1GXH0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">glutathione-disulfide reductase</fullName>
            <ecNumber evidence="2">1.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PGAL8A_00291600</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="9">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.7" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528520.1">
        <property type="nucleotide sequence ID" value="XM_028671915.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXH0"/>
    <dbReference type="GeneID" id="39731449"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00291600"/>
    <dbReference type="OMA" id="VTMAPWG"/>
    <dbReference type="OrthoDB" id="5956163at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004362">
        <property type="term" value="F:glutathione-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.30:FF:000003">
        <property type="entry name" value="Glutathione reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000277">
        <property type="entry name" value="Glutathione reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046952">
        <property type="entry name" value="GSHR/TRXR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42737">
        <property type="entry name" value="GLUTATHIONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42737:SF2">
        <property type="entry name" value="GLUTATHIONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="FAD/NAD-linked reductases, dimerisation (C-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 9 11" id="KW-0274">FAD</keyword>
    <keyword evidence="3 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7 11" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012995248" description="glutathione-disulfide reductase" evidence="12">
        <location>
            <begin position="26"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="14">
        <location>
            <begin position="49"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridine nucleotide-disulphide oxidoreductase dimerisation" evidence="13">
        <location>
            <begin position="422"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="526"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="225"/>
            <end position="232"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="354"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="10">
        <location>
            <begin position="86"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG95712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="541" mass="62172" checksum="379156A3269A7A35" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXJ8</accession>
    <name>A0A1J1GXJ8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Centrin-3, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CEN3</name>
        <name evidence="6" type="ORF">PGAL8A_00486900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530092.1">
        <property type="nucleotide sequence ID" value="XM_028673662.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXJ8"/>
    <dbReference type="GeneID" id="39733402"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00486900"/>
    <dbReference type="OMA" id="EFFMIMK"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000077">
        <property type="entry name" value="Centrin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000301">
        <property type="entry name" value="EF-hand calcium-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050145">
        <property type="entry name" value="Centrin_CML-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23050">
        <property type="entry name" value="CALCIUM BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="35"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="71"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="108"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="144"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="179" mass="20850" checksum="E32E7FF0920BD42D" modified="2017-02-15" version="1">MINRKSEGVNFTPRAIANRPISSNRRRGRNEITDEQKNEIKEAFDLFDTEKTGKIDYHELKVAIRALGFDVKKADVIELMREYDKSNSGHIDYNDFLDIMTQKISERDPTEEIIKAFKLFDDDDTGKISLKNLRRVSRELGENLSDDELQAMIDEFDKDMDGEISQEEFLSIMKQTSLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXJ9</accession>
    <name>A0A1J1GXJ9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00322600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000049">
        <property type="protein sequence ID" value="CRG96013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528821.1">
        <property type="nucleotide sequence ID" value="XM_028672250.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXJ9"/>
    <dbReference type="GeneID" id="39731759"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00322600"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022139">
        <property type="entry name" value="Fam-L/Fam-M-like_plasmodium"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12420">
        <property type="entry name" value="DUF3671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="187" mass="22426" checksum="8412DCE70A1D5872" modified="2017-02-15" version="1">MKTLILFLKITTFLLLIWMYQFFYNCDSYKTLIDKNILQTKNELKYERVLTEGDTAGQKQTNAEGCKEECPVEKKKKEKKIKYWHFPLIRQNPYNRWQVVNNPALFERLKNETSGMDPKWIDHKWNNEWNKISENKVNELSLIFNRSDISKVEKEKLILGVKDELFGLFAEFLDECKKEMRGNKEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXP3</accession>
    <name>A0A1J1GXP3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00480700</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530031.1">
        <property type="nucleotide sequence ID" value="XM_028673594.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXP3"/>
    <dbReference type="GeneID" id="39733340"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00480700"/>
    <dbReference type="OMA" id="WYLVCTD"/>
    <dbReference type="OrthoDB" id="360161at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00268">
        <property type="entry name" value="DEADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044742">
        <property type="entry name" value="DEAD/DEAH_RhlB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF15">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="225"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="420"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="163"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG97228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="638" mass="74796" checksum="CBE7AB9ADC437D14" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXQ6</accession>
    <name>A0A1J1GXQ6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00482300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530047.1">
        <property type="nucleotide sequence ID" value="XM_028673612.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXQ6"/>
    <dbReference type="GeneID" id="39733356"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00482300"/>
    <dbReference type="OrthoDB" id="371207at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="298"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="381"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="412" mass="48918" checksum="F1F1D4E90CA05A88" modified="2017-02-15" version="1">MEDLEIKQALFKKENEQNNEKCEFCKTRYRKFINKFLSWEIVLLLTHILVFLIIIYKLIMDKKLRSSNNKLFRSFNSIGHFTQGFLFVVLLVPFKFTKKITKFLINTSEKKDIQENVMRRNVDIENSNKSINITEEKEIKFDSNEEANSITNNENLIDKNKDDELTEYLSDENKLEKKISLEENSTQEKKKRVYFNENISVKEGYINNDKINKNTENSVCDSFVNKLVFCDNVPNYKKKEIEYFFLCAKLFSSNKSYILFVIKYVTSFILMFAYPLYNLIKRKILYKYFYFSSYYINLYDFASGLSVGSSLVLIYGLTKFFISYFVKSKKGETFKFYDNYAFVNDINCLCDENIKINVKNNPYLKNITMNYFNSYHNYKNLLFAGLIILSIICIFSFGFSFISLNTYKLSIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXS1</accession>
    <name>A0A1J1GXS1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">CCR4-NOT transcription complex subunit 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00331100</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528901.1">
        <property type="nucleotide sequence ID" value="XM_028672339.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731841"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00331100"/>
    <dbReference type="OMA" id="YYLCILN"/>
    <dbReference type="OrthoDB" id="1933107at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030015">
        <property type="term" value="C:CCR4-NOT core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000288">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.800:FF:000003">
        <property type="entry name" value="CCR4-NOT transcription complex subunit 1,putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.790">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.840">
        <property type="entry name" value="CCR4-NOT transcription complex subunit 1 TTP binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007196">
        <property type="entry name" value="CCR4-Not_Not1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032191">
        <property type="entry name" value="CNOT1_CAF1_bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024557">
        <property type="entry name" value="CNOT1_dom_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032193">
        <property type="entry name" value="CNOT1_TTP_bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038535">
        <property type="entry name" value="CNOT1_TTP_bind_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040398">
        <property type="entry name" value="Not1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13162">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13162:SF8">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16415">
        <property type="entry name" value="CNOT1_CAF1_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16417">
        <property type="entry name" value="CNOT1_TTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12842">
        <property type="entry name" value="DUF3819"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04054">
        <property type="entry name" value="Not1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2577"/>
            <end position="2597"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2618"/>
            <end position="2634"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1 TTP binding" evidence="12">
        <location>
            <begin position="10"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1 CAF1-binding" evidence="11">
        <location>
            <begin position="500"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1" evidence="10">
        <location>
            <begin position="905"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-Not complex component Not1 C-terminal" evidence="9">
        <location>
            <begin position="2556"/>
            <end position="2911"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1557"/>
            <end position="1590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2150"/>
            <end position="2471"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1987"/>
            <end position="2017"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1566"/>
            <end position="1578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="2181"/>
            <end position="2455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="2456"/>
            <end position="2467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF16417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG96096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3133" mass="365421" checksum="49A9CC2755A31762" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY16</accession>
    <name>A0A1J1GY16_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00495500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530178.1">
        <property type="nucleotide sequence ID" value="XM_028673758.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733488"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00495500"/>
    <dbReference type="OMA" id="GLINNHY"/>
    <dbReference type="OrthoDB" id="365880at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="133"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="688"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="847"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1204"/>
            <end position="1247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1306"/>
            <end position="1326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1340"/>
            <end position="1374"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="481"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="143"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="849"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="880"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="893"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="934"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="975"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1204"/>
            <end position="1230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1231"/>
            <end position="1247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1306"/>
            <end position="1317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1345"/>
            <end position="1374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1537" mass="178289" checksum="21BFB2B39F1EF08B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY40</accession>
    <name>A0A1J1GY40_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Tyrosine recombinase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">INT</name>
        <name evidence="6" type="ORF">PGAL8A_00504900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530277.1">
        <property type="nucleotide sequence ID" value="XM_028673868.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY40"/>
    <dbReference type="GeneID" id="39733582"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00504900"/>
    <dbReference type="OrthoDB" id="371585at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00796">
        <property type="entry name" value="INT_Rci_Hp1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="entry name" value="Intergrase catalytic core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050090">
        <property type="entry name" value="Tyrosine_recombinase_XerCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30349:SF41">
        <property type="entry name" value="INTEGRASE_RECOMBINASE PROTEIN MJ0367-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30349">
        <property type="entry name" value="PHAGE INTEGRASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="DNA breaking-rejoining enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009618945" evidence="3">
        <location>
            <begin position="23"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="Core-binding (CB)" evidence="5">
        <location>
            <begin position="130"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="4">
        <location>
            <begin position="234"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="430" mass="50463" checksum="1555EC2FF95B31A8" modified="2017-02-15" version="1">MNKILKNVLWILFLKHIKNVSSYCTTQIKTYDFIRIKMNKKCCKYKYCSVKNNLLLNNNIGINVNEKENTNSYNEQTEYNDKKKLKLEKKKKKKKRKTNDVLKCKMCKKILKPKVKFCIYCGTNVSVQKIKLKKYIEEIYLPIRKEEVSENTFRVEKGFWKDILTKLGKYELDELGPNNWESFLKYLKGKNCSPRTLALYQSTYQQSLKYALYRDYLKSIHHFRKIKKSTIPRRKITPLSPKEIELLLKNSSDMHRAIFGLCIGIGLRPSEVLRILWEDVNFEKKEIFIKGQKTKYSSTSIPLTNFAYIELIKWWEIENKPKKGLCFYSETLKNKFNYTETKTPLKTFKTALKGAAKRAGLEISEDGKKRRIFPYLLRHSFATIAATSNPPVPLPVAQAIMRHSSSKMLLDTYTKAGNNIIRDGLDNFKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY78</accession>
    <name>A0A1J1GY78_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytoplasmic dynein intermediate chain, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00479500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530019.1">
        <property type="nucleotide sequence ID" value="XM_028673581.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY78"/>
    <dbReference type="GeneID" id="39733328"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00479500"/>
    <dbReference type="OMA" id="LYTFDCF"/>
    <dbReference type="OrthoDB" id="4189at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045504">
        <property type="term" value="F:dynein heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045503">
        <property type="term" value="F:dynein light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010970">
        <property type="term" value="P:transport along microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050687">
        <property type="entry name" value="Dynein_IC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442:SF22">
        <property type="entry name" value="CYTOPLASMIC DYNEIN 1 INTERMEDIATE CHAIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12442">
        <property type="entry name" value="DYNEIN INTERMEDIATE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="663"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="202"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="22"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="202"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="228"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="238"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="251"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="732" mass="85154" checksum="DEF4AACBCDC4BD5C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYE1</accession>
    <name>A0A1J1GYE1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00323700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000051">
        <property type="protein sequence ID" value="CRG96024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528832.1">
        <property type="nucleotide sequence ID" value="XM_028672262.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYE1"/>
    <dbReference type="GeneID" id="39731770"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00323700"/>
    <dbReference type="OrthoDB" id="10583799at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="217" mass="26238" checksum="C5FEE31A245D183C" modified="2017-02-15" version="1">MEIMSLRIINEMYTLLKYERILAEGNTEGKEQTNAEGCLNKSPLDNEKKESTDPDKYTYPYNYWFKFKLPILWERFNNETSQMDHEWKLKKWYVDFQMFSNKKFNDLLYPIIRSNIPDKQKKEKIDRFMNEFDSEFNKFLCECKKDMTNNKTESESKKEITGNKTESEYKKEMTDNKKEYESKNEMTDKKTESKSMNEVTDNKTESKSKEDMRENTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYM0</accession>
    <name>A0A1J1GYM0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein disulfide-isomerase</fullName>
            <ecNumber evidence="3">5.3.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00361600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Catalyzes the rearrangement of -S-S- bonds in proteins.</text>
            <dbReference type="EC" id="5.3.4.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.4.1" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529197.1">
        <property type="nucleotide sequence ID" value="XM_028672668.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYM0"/>
    <dbReference type="GeneID" id="39732146"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00361600"/>
    <dbReference type="OMA" id="AIWVVQF"/>
    <dbReference type="OrthoDB" id="2121326at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034976">
        <property type="term" value="P:response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057305">
        <property type="entry name" value="Thioredox_PDIA6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45815">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45815:SF3">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24541">
        <property type="entry name" value="Thioredox_PDIA6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012565846" description="protein disulfide-isomerase" evidence="7">
        <location>
            <begin position="24"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="8">
        <location>
            <begin position="11"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="8">
        <location>
            <begin position="144"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG96392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="422" mass="49092" checksum="7E87900AB3218607" modified="2017-02-15" version="1">MKIFHKVFFFLFLISLFMKVSFCLYKDIEEIITVDSLNKFEELLASKKVCVVQFYATWCRVSRGFANDFVSISKALKDDVTFIAIKNEEIANKYGIEIYPSLQLFFVNGNKKEVEKFDGNYKIKDVVTFIYDSIKNYRLRELNIDTSKNKSSYKKNSKNKNDGKVIILNDKNFDKNVLQNDDNVWFVFFYAPWCGHSKPIHPMFDELAKKVSHLKNAKIAKIDATVEQRTAQTYRISHYPSFRLFPAGNKNSHSAIDYNDSRTIEDLYQFFLKHYVEKKELIQLTSQQVFDEYCEKGVCLLAFLPNKEDTEPTYFKSYISILKNVLKDVNNLPVTLMWTQAGDQLDIVQKLNLTFGFPTVIALSFSKNVYSILKGNYSESSIKNFITQMMMGKSSVENLVTFTVKDTPKFTFDNMNEINTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ18</accession>
    <name>A0A1J1GZ18_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DnaJ protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00024000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DPH4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530605.1">
        <property type="nucleotide sequence ID" value="XM_028674231.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ18"/>
    <dbReference type="GeneID" id="39728763"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00024000"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001671">
        <property type="term" value="F:ATPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.660.10">
        <property type="entry name" value="DPH Zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007872">
        <property type="entry name" value="DPH_MB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036671">
        <property type="entry name" value="DPH_MB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45255">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45255:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05207">
        <property type="entry name" value="Zn_ribbon_CSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144217">
        <property type="entry name" value="CSL zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51074">
        <property type="entry name" value="DPH_MB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="J" evidence="5">
        <location>
            <begin position="8"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="DPH-type MB" evidence="6">
        <location>
            <begin position="83"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="138" mass="16729" checksum="E12DE89E9DA4BD37" modified="2017-02-15" version="1">MNMNEDKDPYSILKVEKNCDVETLKKQFKKLAILYHPDKSNYHLFKENNEKKEKDIDFVTLVWAYEKILKEIECNNKSEKYENALNINKNDLKYIKEEETYIYFCRCGDFFLFNENLYYEYYVIQVCQSCSSSVYIIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZG2</accession>
    <name>A0A1J1GZG2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00027600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530641.1">
        <property type="nucleotide sequence ID" value="XM_028674271.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728799"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00027600"/>
    <dbReference type="OMA" id="TQYSHIS"/>
    <dbReference type="OrthoDB" id="9628807at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="847"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1794"/>
            <end position="1816"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2323"/>
            <end position="2343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2472"/>
            <end position="2511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2962"/>
            <end position="2998"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3040"/>
            <end position="3080"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="904"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="857"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1806"/>
            <end position="1816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2330"/>
            <end position="2340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2479"/>
            <end position="2490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="2497"/>
            <end position="2508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2962"/>
            <end position="2971"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2972"/>
            <end position="2985"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="3040"/>
            <end position="3066"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3492" mass="412119" checksum="5FC8C9EF521EACF6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZJ2</accession>
    <name>A0A1J1GZJ2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00042100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG97992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530789.1">
        <property type="nucleotide sequence ID" value="XM_028674437.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728946"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00042100"/>
    <dbReference type="OMA" id="NPPELTY"/>
    <dbReference type="OrthoDB" id="375150at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053121">
        <property type="entry name" value="Spore_Coat_Assembly"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35365">
        <property type="entry name" value="LP04239P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35365:SF18">
        <property type="entry name" value="MUCIN-19-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="657"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="311"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="366"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="428"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1341"/>
            <end position="1361"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="121"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1019"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1110"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="313"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="373"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="387"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="428"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1551" mass="182566" checksum="0861F4EE9A52166C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZM0</accession>
    <name>A0A1J1GZM0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Oxidation resistance protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00432600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the OXR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529549.1">
        <property type="nucleotide sequence ID" value="XM_028673058.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZM0"/>
    <dbReference type="GeneID" id="39732858"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00432600"/>
    <dbReference type="OrthoDB" id="26679at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006571">
        <property type="entry name" value="TLDc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23354:SF62">
        <property type="entry name" value="MUSTARD, ISOFORM V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23354">
        <property type="entry name" value="NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07534">
        <property type="entry name" value="TLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00584">
        <property type="entry name" value="TLDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51886">
        <property type="entry name" value="TLDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TLDc" evidence="6">
        <location>
            <begin position="585"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="224"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="818"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="224"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="924" mass="107573" checksum="8B6CE015BC68BEBA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZV3</accession>
    <name>A0A1J1GZV3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00412900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000064">
        <property type="protein sequence ID" value="CRG96547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529352.1">
        <property type="nucleotide sequence ID" value="XM_028672839.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZV3"/>
    <dbReference type="GeneID" id="39732659"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00412900"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="139" mass="16483" checksum="621D3986D8257B94" modified="2017-02-15" version="1">MKTFILYLKIFTFILLIWIFPFLYNDDSSKSMINRDILQTKIGLKHERMLAEGDISEKNSSYIKKLVEHYPSGEVEMTQENLVYLIDMFIKCYNANIKTNIADNVLLNEENEMRYKCSDKILNAYRNNISVDKAIEHYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H043</accession>
    <name>A0A1J1H043_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00035700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530720.1">
        <property type="nucleotide sequence ID" value="XM_028674359.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H043"/>
    <dbReference type="GeneID" id="39728881"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00035700"/>
    <dbReference type="OMA" id="KQYRCVA"/>
    <dbReference type="OrthoDB" id="392488at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="564" mass="68064" checksum="8BA041814CBF4C05" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0C7</accession>
    <name>A0A1J1H0C7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DNA2/NAM7 helicase-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00455800</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA2/NAM7 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529781.1">
        <property type="nucleotide sequence ID" value="XM_028673317.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733091"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00455800"/>
    <dbReference type="OMA" id="IAGTCKS"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050534">
        <property type="entry name" value="Coronavir_polyprotein_1ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018838">
        <property type="entry name" value="ZGRF1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43788:SF8">
        <property type="entry name" value="DNA-BINDING PROTEIN SMUBP-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43788">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10382">
        <property type="entry name" value="ZGRF1-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="5'-3' DNA helicase ZGRF1-like N-terminal" evidence="8">
        <location>
            <begin position="9"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="9">
        <location>
            <begin position="1061"/>
            <end position="1366"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="10">
        <location>
            <begin position="1471"/>
            <end position="1716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="498"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1190"/>
            <end position="1217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="503"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG96978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1738" mass="207483" checksum="2DAC4EA5167B2F82" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0J9</accession>
    <name>A0A1J1H0J9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Proteasome subunit alpha type-6, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00052600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase T1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530888.1">
        <property type="nucleotide sequence ID" value="XM_028674547.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0J9"/>
    <dbReference type="GeneID" id="39729051"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00052600"/>
    <dbReference type="OMA" id="YGYDMPV"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03754">
        <property type="entry name" value="proteasome_alpha_type_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034642">
        <property type="entry name" value="Proteasome_subunit_alpha6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4 6 8" id="KW-0647">Proteasome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="7">
        <location>
            <begin position="9"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG98091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="260" mass="29583" checksum="01E006CD83289C69" modified="2017-02-15" version="1">MVRPSQSMYDRHLTIFSPDGNLYQIEYAIKAVKNTNITSIGVKGENCAVIISQKKMATQYISQDKLLDYNNITNIYNITDEIGCSMVGMPGDCLSMVYKARSEASEFLYLNGYNVNVETLCRNICDKIQVYTQHAYMRLHACSGIIIGMNEENKPELYKFDPSGFCAGYRACVIGNKEQESVCILERLLEKRKKKIQQETLEEDIQNTIILAIEALQTVLGFDLKANEIEMAVVSKNNPNFTQISEKEIDNYLTYIAERD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0K0</accession>
    <name>A0A1J1H0K0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00040600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000129">
        <property type="protein sequence ID" value="CRG97971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530770.1">
        <property type="nucleotide sequence ID" value="XM_028674414.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0K0"/>
    <dbReference type="GeneID" id="39728930"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00040600"/>
    <dbReference type="OMA" id="NQWINEE"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="207"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="312"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="375"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="126"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="207"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="218"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="252"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="319"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="375"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="400"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="495" mass="54860" checksum="F384FAE20C6F4CBD" modified="2017-02-15" version="1" fragment="single">MDTEKEPLIRKRRHISGPLASGTLQRGLLKDWRKRFSNGVDFRISKIKNEKSPKMKRRLCRHLNYWVDERRDYFTTTLRKQLLLLGDINKHWADTHNSVVEKLKASFNDSCKRIENKNKKDVRDKKKVMEDFCEDKEERLQELNENVTEEKCIEYSNWLNENKSNFEKKKWINEQMIFDENLEISENCTLNDMNTFVSSLDCSKINKKENDSCDSKTSESCNPSKRLTPGSSSDNGSDRASIETIKIKPNATTNLPTTTINSTTTTEITSNTSIESTTPTPGSTQKLTSTIVSIHSDPNLPKPAALKAIEPEISQRDVSPTTPTPSSTSKIASTTIPTPSDEDLPKVLPLIADKPMDKQVINDIIPTFRNNDISPTVSDSSESSISPIFGSMNTNISGNSQTESPPTTPTSAPNITSPSIAIQKNMPTTIQVPITNFTSSSNATLNKPSISPTSANVNATELTTMFKTSASSGNTSKPTSTIKAANISTNLSITS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0T6</accession>
    <name>A0A1J1H0T6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00061600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530976.1">
        <property type="nucleotide sequence ID" value="XM_028674645.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0T6"/>
    <dbReference type="GeneID" id="39729141"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00061600"/>
    <dbReference type="OMA" id="EASICIH"/>
    <dbReference type="OrthoDB" id="387121at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="637"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="704"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="117"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="167"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="640"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="712"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="726"/>
            <end position="742"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1158" mass="137037" checksum="BA854CB255FC78F1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0V7</accession>
    <name>A0A1J1H0V7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00449000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529712.1">
        <property type="nucleotide sequence ID" value="XM_028673239.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0V7"/>
    <dbReference type="GeneID" id="39733023"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00449000"/>
    <dbReference type="OrthoDB" id="385784at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3030.10">
        <property type="entry name" value="Gametocyte protein Pfg27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036469">
        <property type="entry name" value="Pfg27_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="256" mass="30047" checksum="9D368EDF51E886EB" modified="2017-02-15" version="1">MKSSKLFCFFNLLFFIILSVIHLFNVNLFSNVICHSLEKNYQYFWKKMERNLAEGESSSQITGKKSDDFQPGILYEQIIIICDCLFDGHKDTLFNIRSLPDDNPEPLCFKDGLFIGDKLYHRLQWSQLNPSYKLIRNEIKRVKECNALIISMGNIRDVIEYVLDIFKLENDLTKVLLHSMIGKSQEDITRIIRDESSIISKILEELQLRNLQLPESQVRRSMFRISRRAHDIANELGILYGHIPEPIDCYLEEYSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0X2</accession>
    <name>A0A1J1H0X2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Plasmodium RESA N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00000400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000145">
        <property type="protein sequence ID" value="CRG98219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028531016.1">
        <property type="nucleotide sequence ID" value="XM_028674689.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0X2"/>
    <dbReference type="GeneID" id="39728526"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00000400"/>
    <dbReference type="OMA" id="FCILLEC"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="228" mass="27864" checksum="11A834FF9F863850" modified="2017-02-15" version="1">MKNYPIYPYIHKGGTTKKKGSIVRVQFKLIILLYFVLFCILLECLFNQKSQSVSIIKFNKEYLRILAEEEEEIKNKILKMDNPYGIYSIHFNIKTGALIERMLSDWQNLCNDLRKKFSSYEREWEVEHFDQWYNKISDDIKSFHEEVLAEYIPIWVSRHNDKECYKYFEKKRKELSKLCNILEEWFMKYIKKCKDEWYPSNCKNVPTFYKSIFKNKKKDYMPLINNQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H124</accession>
    <name>A0A1J1H124_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin), chloroplastic</fullName>
            <ecNumber evidence="11">1.17.7.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">GcpE</name>
        <name evidence="16" type="ORF">PGAL8A_00482100</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + 2 reduced [2Fe-2S]-[ferredoxin] + H(+)</text>
            <dbReference type="Rhea" id="RHEA:26119"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:58483"/>
            <dbReference type="ChEBI" id="CHEBI:128753"/>
            <dbReference type="EC" id="1.17.7.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="9">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 5/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the IspG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.7.1" evidence="11"/>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530045.1">
        <property type="nucleotide sequence ID" value="XM_028673609.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H124"/>
    <dbReference type="GeneID" id="39733354"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00482100"/>
    <dbReference type="OMA" id="LYVGKEC"/>
    <dbReference type="OrthoDB" id="429167at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046429">
        <property type="term" value="F:4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity (ferredoxin)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.20:FF:000005">
        <property type="entry name" value="4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.413.10:FF:000006">
        <property type="entry name" value="4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="entry name" value="Dihydropteroate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="entry name" value="Sulfite Reductase Hemoprotein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00159">
        <property type="entry name" value="IspG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017178">
        <property type="entry name" value="IspG_atypical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004588">
        <property type="entry name" value="IspG_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058579">
        <property type="entry name" value="IspG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058578">
        <property type="entry name" value="IspG_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00612">
        <property type="entry name" value="ispG_gcpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30454">
        <property type="entry name" value="4-HYDROXY-3-METHYLBUT-2-EN-1-YL DIPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30454:SF0">
        <property type="entry name" value="4-HYDROXY-3-METHYLBUT-2-EN-1-YL DIPHOSPHATE SYNTHASE (FERREDOXIN), CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04551">
        <property type="entry name" value="GcpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26540">
        <property type="entry name" value="GcpE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037336">
        <property type="entry name" value="IspG_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56014">
        <property type="entry name" value="Nitrite and sulphite reductase 4Fe-4S domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IspG TIM-barrel" evidence="14">
        <location>
            <begin position="121"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="IspG C-terminal" evidence="15">
        <location>
            <begin position="756"/>
            <end position="844"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00051119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00060620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00061554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00067018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00072132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00083306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF26540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="CRG97242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="853" mass="98343" checksum="BC55AC8730460980" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2B9</accession>
    <name>A0A1J1H2B9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00505100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530279.1">
        <property type="nucleotide sequence ID" value="XM_028673870.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2B9"/>
    <dbReference type="GeneID" id="39733584"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00505100"/>
    <dbReference type="OMA" id="TREVWSY"/>
    <dbReference type="OrthoDB" id="374923at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.510">
        <property type="entry name" value="GLE1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038506">
        <property type="entry name" value="GLE1-like_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="357" mass="42301" checksum="263DC80FA8E1D726" modified="2017-02-15" version="1">MEFFIWKEDDIKIDEELKKTLNEGIIKYDDIIDIHNKLKIFRSFKFDNLNYHSDKCILAREFVIIYMLSYKKYIESLKDTNLQIIIKTIKRTILSVNNIISNITEQILKCFCMLRNLYNDILKLNNVYLTDYCLFSIIEGILGILDDEKIHQAKASIWGISCFLSLIISNYKKAYFIYKGIVSYKCIYTIPLFFEIPEYLSKEKLYDIILEQNDEFLCSNYSRIEAFIKLHLSIFIILNDTREIWCYLTEILNSAFRRKTYIYFCLIYSSLDISAYYCKLTFGNYFESLLILLKTKLMPLLEEELKNKPPPTNVEKIVDYYIKKLYVEHLNNNLNPTLPEGIVVIPDEKILYLGVGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2N3</accession>
    <name>A0A1J1H2N3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphodiesterase</fullName>
            <ecNumber evidence="6">3.1.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PDEgamma</name>
        <name evidence="9" type="ORF">PGAL8A_00517900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="6">Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cyclic nucleotide phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.-" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530407.1">
        <property type="nucleotide sequence ID" value="XM_028674012.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2N3"/>
    <dbReference type="GeneID" id="39733712"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00517900"/>
    <dbReference type="OMA" id="IFVIRYI"/>
    <dbReference type="OrthoDB" id="342865at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004114">
        <property type="term" value="F:3',5'-cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1300.10">
        <property type="entry name" value="3'5'-cyclic nucleotide phosphodiesterase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023088">
        <property type="entry name" value="PDEase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002073">
        <property type="entry name" value="PDEase_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036971">
        <property type="entry name" value="PDEase_catalytic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023174">
        <property type="entry name" value="PDEase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11347">
        <property type="entry name" value="CYCLIC NUCLEOTIDE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00233">
        <property type="entry name" value="PDEase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00387">
        <property type="entry name" value="PDIESTERASE1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00126">
        <property type="entry name" value="PDEASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51845">
        <property type="entry name" value="PDEASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="62"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="91"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="PDEase" evidence="8">
        <location>
            <begin position="400"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="481"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="481"/>
            <end position="485"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="485"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="521"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="522"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="522"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="522"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="631"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="631"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="683"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG97606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="763" mass="90760" checksum="FA8A89FF2CA8C7C7" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2V9</accession>
    <name>A0A1J1H2V9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Trafficking protein particle complex subunit 8, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">TRS85</name>
        <name evidence="1" type="ORF">PGAL8A_00026300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530628.1">
        <property type="nucleotide sequence ID" value="XM_028674257.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728786"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00026300"/>
    <dbReference type="OMA" id="FMMARQA"/>
    <dbReference type="OrthoDB" id="437922at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990072">
        <property type="term" value="C:TRAPPIII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024420">
        <property type="entry name" value="TRAPP_III_complex_Trs85"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12975:SF6">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12975">
        <property type="entry name" value="TRANSPORT PROTEIN TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12739">
        <property type="entry name" value="TRAPPC-Trs85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2300" mass="273779" checksum="3A2A6C8702E65289" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3Z0</accession>
    <name>A0A1J1H3Z0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00063800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530996.1">
        <property type="nucleotide sequence ID" value="XM_028674667.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3Z0"/>
    <dbReference type="GeneID" id="39729163"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00063800"/>
    <dbReference type="OMA" id="NYDQVFA"/>
    <dbReference type="OrthoDB" id="376231at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG98199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="970" mass="117862" checksum="187E515941F0BE01" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2012-05-16" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>H7CDX3</accession>
    <name>H7CDX3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Apicoplast ribosomal protein L16, putative</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="5">Large subunit ribosomal protein 16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpl16</name>
        <name evidence="6" type="synonym">RPL16</name>
        <name evidence="6" type="ORF">PGAL8A_API01700</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <geneLocation type="apicoplast" evidence="5"/>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Mol. Biol. Evol." volume="29" first="2095" last="2099">
            <title>The Plasmodium Apicoplast Genome: Conserved Structure and Close Relationship of P. ovale to Rodent Malaria Parasites.</title>
            <authorList>
                <person name="Arisue N."/>
                <person name="Hashimoto T."/>
                <person name="Mitsui H."/>
                <person name="Palacpac N.M.Q."/>
                <person name="Kaneko A."/>
                <person name="Kawai S."/>
                <person name="Hasegawa M."/>
                <person name="Tanabe K."/>
                <person name="Horii T."/>
            </authorList>
            <dbReference type="PubMed" id="22396524"/>
            <dbReference type="DOI" id="10.1093/molbev/mss082"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">A8</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL16 family.</text>
    </comment>
    <dbReference type="EMBL" id="AB649424">
        <property type="protein sequence ID" value="BAL70743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LN835293">
        <property type="protein sequence ID" value="CRG98232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009325459.1">
        <property type="nucleotide sequence ID" value="NC_031963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="H7CDX3"/>
    <dbReference type="GeneID" id="30315810"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_API01700"/>
    <dbReference type="OMA" id="KGAVEYW"/>
    <dbReference type="OrthoDB" id="268521at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Apicoplast API"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01433">
        <property type="entry name" value="Ribosomal_L16_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.10">
        <property type="entry name" value="Ribosomal protein L10e/L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047873">
        <property type="entry name" value="Ribosomal_uL16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000114">
        <property type="entry name" value="Ribosomal_uL16_bact-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016180">
        <property type="entry name" value="Ribosomal_uL16_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036920">
        <property type="entry name" value="Ribosomal_uL16_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12220">
        <property type="entry name" value="50S/60S RIBOSOMAL PROTEIN L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12220:SF13">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL16M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00252">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00060">
        <property type="entry name" value="RIBOSOMALL16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54686">
        <property type="entry name" value="Ribosomal protein L16p/L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0933">Apicoplast</keyword>
    <keyword evidence="5" id="KW-0934">Plastid</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAL70743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG98232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="131" mass="15207" checksum="9CE571C23A1CDFD7" modified="2012-05-16" version="1">MNILFNNKIQKGKIKGIFNLKFLNLYWGIISLNSGFITKNQLDTSKFIINKFIKKIGKYNICIKCNKSLTKKSLKTRMGAGKGSIELYVGIVKKYKLLFEISKISLKEIFMITKILSYKLPFKLQFIKKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2012-07-11" modified="2026-01-28" version="49" xmlns="https://uniprot.org/uniprot">
    <accession>I2FKD9</accession>
    <name>I2FKD9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">ATP synthase subunit beta</fullName>
            <ecNumber evidence="13">7.1.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ATP5B</name>
        <name evidence="16" type="ORF">PGAL8A_00457400</name>
    </gene>
    <organism evidence="15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2012" name="Gene" volume="502" first="36" last="39">
            <title>Age of the last common ancestor of extant Plasmodium parasite lineages.</title>
            <authorList>
                <person name="Hayakawa T."/>
                <person name="Tachibana S."/>
                <person name="Hikosaka K."/>
                <person name="Arisue N."/>
                <person name="Matsui A."/>
                <person name="Horii T."/>
                <person name="Tanabe K."/>
            </authorList>
            <dbReference type="PubMed" id="22555021"/>
            <dbReference type="DOI" id="10.1016/j.gene.2012.04.037"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="16 17" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Produces ATP from ADP in the presence of a proton gradient across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O + 4 H(+)(in) = ADP + phosphate + 5 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="13">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) and CF(0) have multiple subunits.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="13"/>
    <dbReference type="EMBL" id="AB571148">
        <property type="protein sequence ID" value="BAM15624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="I2FKD9"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00457400"/>
    <dbReference type="OMA" id="SMEEGGW"/>
    <dbReference type="OrthoDB" id="14523at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042776">
        <property type="term" value="P:proton motive force-driven mitochondrial ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18110">
        <property type="entry name" value="ATP-synt_F1_beta_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18115">
        <property type="entry name" value="ATP-synt_F1_beta_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01133">
        <property type="entry name" value="F1-ATPase_beta_CD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1140.10:FF:000001">
        <property type="entry name" value="ATP synthase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.170:FF:000005">
        <property type="entry name" value="ATP synthase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000026">
        <property type="entry name" value="ATP synthase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1140.10">
        <property type="entry name" value="Bovine Mitochondrial F1-atpase, Atp Synthase Beta Chain, Chain D, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01347">
        <property type="entry name" value="ATP_synth_beta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055190">
        <property type="entry name" value="ATP-synt_VA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005722">
        <property type="entry name" value="ATP_synth_F1_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050053">
        <property type="entry name" value="ATPase_alpha/beta_chains"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024034">
        <property type="entry name" value="ATPase_F1/V1_b/a_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01039">
        <property type="entry name" value="atpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15184">
        <property type="entry name" value="ATP SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15184:SF82">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22919">
        <property type="entry name" value="ATP-synt_VA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039072">
        <property type="entry name" value="ATPase_subunit_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47917">
        <property type="entry name" value="C-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="N-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 13" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="7 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 13" id="KW-0139">CF(1)</keyword>
    <keyword evidence="6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="14">
        <location>
            <begin position="194"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="BAM15624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="CRG96994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="532" mass="58206" checksum="CCC3DA61260B8A78" modified="2012-07-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKW5</accession>
    <name>A0A1J1GKW5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fam-h protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00065900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000003">
        <property type="protein sequence ID" value="CRG92955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525777.1">
        <property type="nucleotide sequence ID" value="XM_028669976.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKW5"/>
    <dbReference type="GeneID" id="39729184"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00065900"/>
    <dbReference type="OMA" id="ISIWILQ"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022139">
        <property type="entry name" value="Fam-L/Fam-M-like_plasmodium"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12420">
        <property type="entry name" value="DUF3671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="106"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG92955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="228" mass="26631" checksum="91C5BBEF161CBFC5" modified="2017-02-15" version="1">MRDYINSNFILNSRCNSHTEENFVIEDISTLKKYHKRGKINKLFFFIKISLFTLLIWILLYCENYNYRSWNDKYNLKNKLDLGSKRSLAEGKEVIEPTKEELKVSSSNIQTNLEENNTKVEKLELKEEEKDKKEIIKIENDNVVEKKRESNKKVNSLNLMQKYKSFLRIFNIVSIVALPILSMTLSIIALSSSEKDNKYVNGSNIVTSLYLVLNSILLLDLKSNSNNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL65</accession>
    <name>A0A1J1GL65_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Tubulin gamma chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00080000</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Tubulin is the major constituent of microtubules, protein filaments consisting of alpha- and beta-tubulin heterodimers. Gamma-tubulin is a key component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation. The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Microtubule organizing center</location>
            <location evidence="2">Centrosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the tubulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525919.1">
        <property type="nucleotide sequence ID" value="XM_028670455.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL65"/>
    <dbReference type="GeneID" id="39729324"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00080000"/>
    <dbReference type="OMA" id="HRYISIL"/>
    <dbReference type="OrthoDB" id="10249382at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005813">
        <property type="term" value="C:centrosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000930">
        <property type="term" value="C:gamma-tubulin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02188">
        <property type="entry name" value="gamma_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.600:FF:000004">
        <property type="entry name" value="Tubulin gamma chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000027">
        <property type="entry name" value="Tubulin gamma chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002454">
        <property type="entry name" value="Gamma_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01164">
        <property type="entry name" value="GAMMATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5 9" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="10">
        <location>
            <begin position="48"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="11">
        <location>
            <begin position="250"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG93097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="452" mass="51626" checksum="40E01B1631C134D4" modified="2017-02-15" version="1">MPREIITLQCGQCGNQIGVEFWKQLCNEHNIDQEGILKNNNFLNEDRKDIFFYQADDEHFIPRALLFDLEPRVINSIQTSEYRNLYNPENMFISKEGGGAGNNWGCGYSQGHKVEEEIIDMIDREVDNSDNLEGFILSHSIAGGTGSGMGSYLLELLNDNYSKKMIQTFSVFPLLTNESSDVVVQPYNSILTLKRLILSTDSVVVIDNTSLNRIFVDKLKLNNPTFQQTNTIISNVMSASTTTLRYPGSMNNDMISLISSLIINPKCHFLVTSYTPITIEKHISNVQKTTVLDVMKRLLHTKNIMVSVPVRRGMYISILNIIRGETDPTQVHKGLQRIRDRKLVNFIKWNPASIQVTLAKQSPHVVSTHKVCGLMMANHTSISTLFERCVTQFDRLFKRRAFLENYKKEPMFSSADGQGNFEEMESSKEITQNLIDEYKSAERDDYFNHTYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLG1</accession>
    <name>A0A1J1GLG1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00086700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525985.1">
        <property type="nucleotide sequence ID" value="XM_028671188.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLG1"/>
    <dbReference type="GeneID" id="39729391"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00086700"/>
    <dbReference type="OrthoDB" id="372341at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="330"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="36"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="335"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="366"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="376"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="526" mass="62700" checksum="4C5DB2124ADD6442" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLI7</accession>
    <name>A0A1J1GLI7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Zinc-carboxypeptidase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00099400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the peptidase M14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526110.1">
        <property type="nucleotide sequence ID" value="XM_028672577.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729518"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00099400"/>
    <dbReference type="OMA" id="FQRDDNF"/>
    <dbReference type="OrthoDB" id="10253041at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050821">
        <property type="entry name" value="Cytosolic_carboxypeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12756">
        <property type="entry name" value="CYTOSOLIC CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12756:SF11">
        <property type="entry name" value="CYTOSOLIC CARBOXYPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52035">
        <property type="entry name" value="PEPTIDASE_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M14" evidence="6">
        <location>
            <begin position="871"/>
            <end position="1127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="770"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1131"/>
            <end position="1194"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="33"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="598"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1425"/>
            <end position="1459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="773"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="850"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="1097"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS52035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1946" mass="231261" checksum="935BDF387D740FD5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLX4</accession>
    <name>A0A1J1GLX4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DnaJ protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00109000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526207.1">
        <property type="nucleotide sequence ID" value="XM_028673655.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLX4"/>
    <dbReference type="GeneID" id="39729616"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00109000"/>
    <dbReference type="OMA" id="DMKIESF"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026894">
        <property type="entry name" value="DnaJ_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052423">
        <property type="entry name" value="EMIR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44094">
        <property type="entry name" value="DNAJ HEAT SHOCK N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44094:SF8">
        <property type="entry name" value="DNAJ HEAT SHOCK N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14308">
        <property type="entry name" value="DnaJ-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="154"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="404"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="532"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="408"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="539"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="564" mass="64931" checksum="FC67B2E07ED969BC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLZ4</accession>
    <name>A0A1J1GLZ4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Serine/threonine protein kinase VPS15, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">VPS15</name>
        <name evidence="5" type="ORF">PGAL8A_00116200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526278.1">
        <property type="nucleotide sequence ID" value="XM_028674444.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLZ4"/>
    <dbReference type="GeneID" id="39729687"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00116200"/>
    <dbReference type="OrthoDB" id="242910at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071561">
        <property type="term" value="C:nucleus-vacuole junction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034271">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034272">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045324">
        <property type="term" value="P:late endosome to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045162">
        <property type="entry name" value="Vps15-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17583">
        <property type="entry name" value="PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17583:SF0">
        <property type="entry name" value="PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="471"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="40"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1018" mass="124248" checksum="EC2FF4EDD7BCF8CF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM15</accession>
    <name>A0A1J1GM15_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00110100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526218.1">
        <property type="nucleotide sequence ID" value="XM_028673777.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM15"/>
    <dbReference type="GeneID" id="39729627"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00110100"/>
    <dbReference type="OMA" id="IQKNCYH"/>
    <dbReference type="OrthoDB" id="382155at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37935">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_14, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37935:SF1">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_14, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="156"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="450"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="678" mass="81113" checksum="58FC2793C54330E8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMG4</accession>
    <name>A0A1J1GMG4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00123000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526345.1">
        <property type="nucleotide sequence ID" value="XM_028674744.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMG4"/>
    <dbReference type="GeneID" id="39729755"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00123000"/>
    <dbReference type="OMA" id="WESRPND"/>
    <dbReference type="OrthoDB" id="10575684at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="155" mass="19060" checksum="024B5A0E965B54F0" modified="2017-02-15" version="1" fragment="single">NILNTDKSYGKYNKHFNNIKDLLIKRMLFDWENVCSDLGVRYSLFGREWEQENFNHWYNKISDDIKDFNDKVLAEYTLLWESRPNDKECSTFFKKKKKELSKVCKVIEGWFRKYVKKCKDEWYHLNCQNVPTFYNSIFNYKKINYKPLINNLEYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN17</accession>
    <name>A0A1J1GN17_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00136600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526483.1">
        <property type="nucleotide sequence ID" value="XM_028674898.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN17"/>
    <dbReference type="GeneID" id="39729891"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00136600"/>
    <dbReference type="OMA" id="IKMKCKI"/>
    <dbReference type="OrthoDB" id="372713at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="272"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1217"/>
            <end position="1244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1261" mass="151946" checksum="68FE9E7F453046CD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN29</accession>
    <name>A0A1J1GN29_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cell division cycle protein 48 homologue, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00147800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526594.1">
        <property type="nucleotide sequence ID" value="XM_028675021.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN29"/>
    <dbReference type="GeneID" id="39730002"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00147800"/>
    <dbReference type="OMA" id="VEMRHFR"/>
    <dbReference type="OrthoDB" id="27435at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034098">
        <property type="term" value="C:VCP-NPL4-UFD1 AAA ATPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097352">
        <property type="term" value="P:autophagosome maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051228">
        <property type="term" value="P:mitotic spindle disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030970">
        <property type="term" value="P:retrograde protein transport, ER to cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19519">
        <property type="entry name" value="RecA-like_CDC48_r1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.330.10:FF:000001">
        <property type="entry name" value="Cell division control 48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000079">
        <property type="entry name" value="Cell division cycle protein 48 homologue"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.40.20:FF:000003">
        <property type="entry name" value="Transitional endoplasmic reticulum ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000012">
        <property type="entry name" value="Transitional endoplasmic reticulum ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000048">
        <property type="entry name" value="Transitional endoplasmic reticulum ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.20.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005938">
        <property type="entry name" value="AAA_ATPase_CDC48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004201">
        <property type="entry name" value="Cdc48_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029067">
        <property type="entry name" value="CDC48_domain_2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003338">
        <property type="entry name" value="CDC4_N-term_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01243">
        <property type="entry name" value="CDC48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF171">
        <property type="entry name" value="NUCLEAR VALOSIN-CONTAINING PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02933">
        <property type="entry name" value="CDC48_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02359">
        <property type="entry name" value="CDC48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00830">
        <property type="entry name" value="ENDOLAPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01072">
        <property type="entry name" value="CDC48_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01073">
        <property type="entry name" value="CDC48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="ADC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54585">
        <property type="entry name" value="Cdc48 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CDC48 N-terminal subdomain" evidence="6">
        <location>
            <begin position="28"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="CDC48" evidence="5">
        <location>
            <begin position="133"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="240"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="513"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="712"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="794"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="720"/>
            <end position="737"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="818" mass="91425" checksum="AB694AB7B3CB67D0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN71</accession>
    <name>A0A1J1GN71_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00148500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526601.1">
        <property type="nucleotide sequence ID" value="XM_028675029.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN71"/>
    <dbReference type="GeneID" id="39730009"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00148500"/>
    <dbReference type="OMA" id="WNEFIRI"/>
    <dbReference type="OrthoDB" id="409663at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="127" mass="15240" checksum="98EB08C8989F0CE0" modified="2017-02-15" version="1">MLNLIPKKIVPKSLLFGKKPIQRIRVGKSKNVLELSLSDVNSIYEDVNENIDLHNKDYNPLKYKKYINYKISALNLIEAYKNEENKKTALTNIKWYSKIRDYFFINFYKNQIQLKEKMVPKFFYPIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNJ0</accession>
    <name>A0A1J1GNJ0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00166500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526778.1">
        <property type="nucleotide sequence ID" value="XM_028669981.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNJ0"/>
    <dbReference type="GeneID" id="39730191"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00166500"/>
    <dbReference type="OMA" id="WEAQFAN"/>
    <dbReference type="OrthoDB" id="417626at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="176" mass="21385" checksum="A15073739D0D6768" modified="2017-02-15" version="1">MNVTRILSNSKILKRNIEFKEVFTPRWFLESPNYSRMPLWRRFFEGQYTNGSFLFFGNTWTSMFAFAFVLWFSRIFDPPPLERVDKYWLNSPKFRILSAFYNEGKRPGVKISLMTYEARYFYRGIDHPFTINEIKDLWFKLKENYLIESIPAIQYPYVFRQYNNVSTPSDLHVHLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNL9</accession>
    <name>A0A1J1GNL9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00178500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000021">
        <property type="protein sequence ID" value="CRG94073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526894.1">
        <property type="nucleotide sequence ID" value="XM_028670109.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNL9"/>
    <dbReference type="GeneID" id="39730312"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00178500"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="101" mass="12007" checksum="7C3757CF4BA37B61" modified="2017-02-15" version="1">MKTFTLYSKIFTFLFIIWIFHCFYNYDYSRSLIDKDALQMKNWLKNERTLAEVGILEKEQNNLRDIYASSNETCKKINKCGDQILDVKSNNNSQNCESYPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNN5</accession>
    <name>A0A1J1GNN5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Plasmodium RESA N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00177800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000021">
        <property type="protein sequence ID" value="CRG94066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526887.1">
        <property type="nucleotide sequence ID" value="XM_028670102.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNN5"/>
    <dbReference type="GeneID" id="39730305"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00177800"/>
    <dbReference type="OMA" id="KLYMNIN"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.180">
        <property type="entry name" value="Plasmodium RESA, N-terminal helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019111">
        <property type="entry name" value="PRESA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044885">
        <property type="entry name" value="PRESA_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09687">
        <property type="entry name" value="PRESAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="Plasmodium RESA N-terminal" evidence="2">
        <location>
            <begin position="93"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="222" mass="26964" checksum="BD98A4663A417BC2" modified="2017-02-15" version="1">MKYSSMQTYILTRKYEKGNNVTLKISTCSPKYQDIIFKKINFRNYMLSRFCLISFLSLFFFFLQDIYKLYMNINLDFQFKNVNSRKLAESNIDKNYDKNYKNSKENVTSDEMLHLWKNHRIEEEKKLVLLLETLMKDLLSKKSHSLDEKKRDELWFKFIEDVRNGVKNTDKKFINDLHFILRDGGCTYEKCVDFIQYGVHIWGAFRYEVKDHWHNKYLNSVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNP5</accession>
    <name>A0A1J1GNP5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00172800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526842.1">
        <property type="nucleotide sequence ID" value="XM_028670051.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730255"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00172800"/>
    <dbReference type="OMA" id="DHYGDDH"/>
    <dbReference type="OrthoDB" id="371833at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051483">
        <property type="entry name" value="MAP7_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15073:SF16">
        <property type="entry name" value="EGF-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15073">
        <property type="entry name" value="MICROTUBULE-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1596"/>
            <end position="1612"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1632"/>
            <end position="1649"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1661"/>
            <end position="1681"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1701"/>
            <end position="1719"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1116"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1749"/>
            <end position="1841"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1927"/>
            <end position="1959"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="2988"/>
            <end position="3010"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="3296"/>
            <end position="3353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="3401"/>
            <end position="3432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="3456"/>
            <end position="3489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="3663"/>
            <end position="3694"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="838"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="2043"/>
            <end position="2071"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1130"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1752"/>
            <end position="1788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1789"/>
            <end position="1810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1817"/>
            <end position="1841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1927"/>
            <end position="1952"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="3296"/>
            <end position="3311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="3318"/>
            <end position="3353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="3401"/>
            <end position="3410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="3411"/>
            <end position="3420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="3421"/>
            <end position="3430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="3666"/>
            <end position="3685"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3767" mass="449455" checksum="8229DE0C9AA35578" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNU9</accession>
    <name>A0A1J1GNU9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein mL43</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00386300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mL43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526980.1">
        <property type="nucleotide sequence ID" value="XM_028670205.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNU9"/>
    <dbReference type="GeneID" id="39732393"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00386300"/>
    <dbReference type="OrthoDB" id="88at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039927">
        <property type="entry name" value="Ribosomal_mL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007741">
        <property type="entry name" value="Ribosomal_mL43/mS25/NADH_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21396">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21396:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05047">
        <property type="entry name" value="L51_S25_CI-B8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00916">
        <property type="entry name" value="L51_S25_CI-B8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein/NADH dehydrogenase" evidence="7">
        <location>
            <begin position="18"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="213" mass="25366" checksum="6D3151FD9A4CF3EA" modified="2017-02-15" version="1">MCSNGVYQLKKILLKYSETGHSSRNVRFFLRFILPDYKEENKHLNFEIQHEQYEEPKAIFEYINNSKYEISLKDIKSKHIVDIINLYKDSAGNTDFLKHGGPKVYSNRRSIQGLWCPSIYSELNAISYLKKKKKNNIKLPKYTRESLNLNYDVIKGNGRWGNENLFPKGFDQRYLKNIFCFPFKDSIPKKNEQNNSCNVYEPHIKSFYKFYKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP19</accession>
    <name>A0A1J1GP19_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Kinesin motor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00386100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526978.1">
        <property type="nucleotide sequence ID" value="XM_028670203.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732391"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00386100"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005875">
        <property type="term" value="C:microtubule associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051231">
        <property type="term" value="P:spindle elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969:SF15">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101908">
        <property type="entry name" value="Putative isomerase YbhE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0505">Motor protein</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="9">
        <location>
            <begin position="144"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="392"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1387"/>
            <end position="1415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="2215"/>
            <end position="2243"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="557"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="940"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1226"/>
            <end position="1318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="1387"/>
            <end position="1402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1403"/>
            <end position="1415"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="228"/>
            <end position="235"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG94157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2892" mass="342583" checksum="261466F29A5F0B5F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP34</accession>
    <name>A0A1J1GP34_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00395300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527070.1">
        <property type="nucleotide sequence ID" value="XM_028670304.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP34"/>
    <dbReference type="GeneID" id="39732483"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00395300"/>
    <dbReference type="OMA" id="YEECENK"/>
    <dbReference type="OrthoDB" id="6013at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="445" mass="54259" checksum="C0B53F57D79EC56D" modified="2017-02-15" version="1">MFKYISRFFTYVFYLLISYNYFMYSCGFNLKKRLIVHFFISNKSFCKNSIFPRRKYKIKYLNKEYTADKCKSNWNNYKKKVVNNENKIKIKFNHLLKEKNNENIQSKNKNKRTLYIVEEKLENISRGKKKKNVEKVKKVKGNKKNEENISKSKEVEDAKSYNKIKEINENEKSNFINENITNNFSNEENKINHKTKSEEINNQGENNYEECENKKRLKDDTVRKKLSELAKLRWKNEEERKKLLLGKKKFKHSEKTKKLLSYKIKLKWKDEKYREKIIEKTRIFNQDENTKKKKSLILKEKWKIKEFRDKMLNNRKPFSLERRKKISEIIKQKWKEEDYKQKTLKAIKDNYKKRKLQVGLNPDLNYIQNVMLFKQLGICAPKIRYFPDIHKEKLRNKKKKKKKKDKENYKEKWKNIYDSILDKNEFQNSSSHLGKIENLSVSTNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPM2</accession>
    <name>A0A1J1GPM2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Signal peptidase complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SPC2</name>
        <name evidence="9" type="ORF">PGAL8A_00395600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Endoplasmic reticulum membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the SPCS2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527073.1">
        <property type="nucleotide sequence ID" value="XM_028670307.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPM2"/>
    <dbReference type="GeneID" id="39732486"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00395600"/>
    <dbReference type="OrthoDB" id="330185at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005787">
        <property type="term" value="C:signal peptidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009582">
        <property type="entry name" value="Spc2/SPCS2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06703">
        <property type="entry name" value="SPC25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="183" mass="21658" checksum="86F966E5F0F74A29" modified="2017-02-15" version="1">MPSKKVSDSNENTYHVNNLYSEQEIKKVTQDYISEKIRELNYMENVHYSNIRILLSLILIFIGSYCSIFVQYKKNPLLMIKLLIAFFVVSVVLFMFEYFYFENAFMILKTNNDAEVKLSCKLDKEKSSLSLVFASNKKVHSTHFDLKKLFNENGYLIRNYAENILKEFLLIQEKNFKLKNGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPM6</accession>
    <name>A0A1J1GPM6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ras-related protein RAB7, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RAB7</name>
        <name evidence="6" type="ORF">PGAL8A_00184700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000024">
        <property type="protein sequence ID" value="CRG94455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527276.1">
        <property type="nucleotide sequence ID" value="XM_028670534.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPM6"/>
    <dbReference type="GeneID" id="39730374"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00184700"/>
    <dbReference type="OMA" id="TSWKDEF"/>
    <dbReference type="OrthoDB" id="1436450at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01862">
        <property type="entry name" value="Rab7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000086">
        <property type="entry name" value="Ras-related small GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47981">
        <property type="entry name" value="RAB FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47981:SF20">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB-7A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0636">Prenylation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG94455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="206" mass="23772" checksum="E46D7FCF6A2A1561" modified="2017-02-15" version="1">MSNKKRTILKVIILGDSGVGKTSLMNQYVNKKFTNQYKATIGADFLTKETMVDNEQITMQIWDTAGQERFQSLGVAFYRGADCCVLVFDLTNYKTYESLESWKDEFLIQASPKDPENFPFVIIGNKVDETNKRKVQSLKVLQWCKSNNNIPYFETSAKNAINVDQAFDEIARKAMKQEHQEEQIYLPETFALNNQSEQKPYKSRCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPR9</accession>
    <name>A0A1J1GPR9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00099300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526109.1">
        <property type="nucleotide sequence ID" value="XM_028672566.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPR9"/>
    <dbReference type="GeneID" id="39729517"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00099300"/>
    <dbReference type="OMA" id="CSARCGC"/>
    <dbReference type="OrthoDB" id="341679at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="128"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="401"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="202"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="401"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="734" mass="87285" checksum="4593A949DDCC066E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPT9</accession>
    <name>A0A1J1GPT9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribosomal RNA methyltransferase FtsJ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00101700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526133.1">
        <property type="nucleotide sequence ID" value="XM_028672832.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPT9"/>
    <dbReference type="GeneID" id="39729542"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00101700"/>
    <dbReference type="OMA" id="CINVSNT"/>
    <dbReference type="OrthoDB" id="429597at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004483">
        <property type="term" value="F:methyltransferase cap1 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006370">
        <property type="term" value="P:7-methylguanosine mRNA capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12760">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050851">
        <property type="entry name" value="mRNA_Cap_2O-Ribose_MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16121">
        <property type="entry name" value="CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16121:SF2">
        <property type="entry name" value="CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="820"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="999"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1002"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1064" mass="128079" checksum="3FBDDB80E491D779" modified="2017-02-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ52</accession>
    <name>A0A1J1GQ52_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">LCCL domain-containing protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00195800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527378.1">
        <property type="nucleotide sequence ID" value="XM_028670647.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730485"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00195800"/>
    <dbReference type="OMA" id="NFCEECC"/>
    <dbReference type="OrthoDB" id="414826at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="beta-trefoil_Ricin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.560">
        <property type="entry name" value="Exo-inulinase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.20">
        <property type="entry name" value="LCCL-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051957">
        <property type="entry name" value="CRISP-LCCL_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000421">
        <property type="entry name" value="FA58C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036056">
        <property type="entry name" value="Fibrinogen-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004043">
        <property type="entry name" value="LCCL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036609">
        <property type="entry name" value="LCCL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF040941">
        <property type="entry name" value="GGGWT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31331:SF1">
        <property type="entry name" value="CYSTEINE RICH SECRETORY PROTEIN LCCL DOMAIN CONTAINING 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31331">
        <property type="entry name" value="LCCL DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G08630)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00754">
        <property type="entry name" value="F5_F8_type_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03815">
        <property type="entry name" value="LCCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00603">
        <property type="entry name" value="LCCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56496">
        <property type="entry name" value="Fibrinogen C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69848">
        <property type="entry name" value="LCCL domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50022">
        <property type="entry name" value="FA58C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50820">
        <property type="entry name" value="LCCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013380424" evidence="2">
        <location>
            <begin position="20"/>
            <end position="1596"/>
        </location>
    </feature>
    <feature type="domain" description="F5/8 type C" evidence="3">
        <location>
            <begin position="288"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="LCCL" evidence="4">
        <location>
            <begin position="749"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="502"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="993"/>
            <end position="1020"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1596" mass="182557" checksum="13F2283FDF1E3D12" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ57</accession>
    <name>A0A1J1GQ57_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Structural maintenance of chromosomes protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00087400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SMC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525992.1">
        <property type="nucleotide sequence ID" value="XM_028671266.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ57"/>
    <dbReference type="GeneID" id="39729398"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00087400"/>
    <dbReference type="OMA" id="NLRCEDR"/>
    <dbReference type="OrthoDB" id="431497at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051276">
        <property type="term" value="P:chromosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1060.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024704">
        <property type="entry name" value="SMC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010935">
        <property type="entry name" value="SMC_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
        <property type="entry name" value="SMC_hinge_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43977">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06470">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005719">
        <property type="entry name" value="SMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00968">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75553">
        <property type="entry name" value="Smc hinge domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC hinge" evidence="4">
        <location>
            <begin position="506"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="174"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="227"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="332"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="727"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="957"/>
            <end position="991"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR005719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1193" mass="140992" checksum="F44B3968007C129F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ69</accession>
    <name>A0A1J1GQ69_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Condensin-2 complex subunit G2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00207400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527492.1">
        <property type="nucleotide sequence ID" value="XM_028670773.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ69"/>
    <dbReference type="GeneID" id="39730601"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00207400"/>
    <dbReference type="OMA" id="NLITYSM"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000070">
        <property type="term" value="P:mitotic sister chromatid segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024741">
        <property type="entry name" value="Condensin2_G2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16199">
        <property type="entry name" value="CONDENSIN-2 COMPLEX SUBUNIT G2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16199:SF4">
        <property type="entry name" value="CONDENSIN-2 COMPLEX SUBUNIT G2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12422">
        <property type="entry name" value="Condensin2nSMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1188" mass="142403" checksum="4EED9FB1BD49DF9A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQQ4</accession>
    <name>A0A1J1GQQ4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ferlin, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00214900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527567.1">
        <property type="nucleotide sequence ID" value="XM_028670856.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730676"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00214900"/>
    <dbReference type="OMA" id="RCYIYAC"/>
    <dbReference type="OrthoDB" id="270970at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007009">
        <property type="term" value="P:plasma membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037721">
        <property type="entry name" value="Ferlin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12546">
        <property type="entry name" value="FER-1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12546:SF33">
        <property type="entry name" value="SPERM VESICLE FUSION PROTEIN FER-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1801"/>
            <end position="1824"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="7">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="7">
        <location>
            <begin position="167"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="7">
        <location>
            <begin position="597"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="7">
        <location>
            <begin position="1592"/>
            <end position="1722"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1829" mass="216048" checksum="5C4537473FEE330B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQT7</accession>
    <name>A0A1J1GQT7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">U6 snRNA-associated Sm-like protein LSm5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">LSM5</name>
        <name evidence="11" type="ORF">PGAL8A_00202500</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">LSm subunits form a heteromer with a doughnut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQT7"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00202500"/>
    <dbReference type="OMA" id="YETTPQG"/>
    <dbReference type="OrthoDB" id="429711at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990726">
        <property type="term" value="C:Lsm1-7-Pat1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005688">
        <property type="term" value="C:U6 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01732">
        <property type="entry name" value="LSm5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000041">
        <property type="entry name" value="U6 snRNA-associated Sm-like protein LSm5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033871">
        <property type="entry name" value="LSm5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20971">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20971:SF0">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="11"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG94628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="105" mass="11874" checksum="28327B38E87870D9" modified="2017-02-15" version="1">MATISSSETFLPLALMDKCIGSKIWIMMKGDKEIVGKLVGFDEYVNMVLEDVTEYTYVNNVKKVNKIKKLLLNGLNITIMVPGGTPVNYYDYEEKLEENIDDKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQW6</accession>
    <name>A0A1J1GQW6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">valine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Valyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00221300</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>tRNA(Val) + L-valine + ATP = L-valyl-tRNA(Val) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:10704"/>
            <dbReference type="Rhea" id="RHEA-COMP:9672"/>
            <dbReference type="Rhea" id="RHEA-COMP:9708"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78537"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.9" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527631.1">
        <property type="nucleotide sequence ID" value="XM_028670927.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQW6"/>
    <dbReference type="GeneID" id="39730740"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00221300"/>
    <dbReference type="OMA" id="PPNCATN"/>
    <dbReference type="OrthoDB" id="629407at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004832">
        <property type="term" value="F:valine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006438">
        <property type="term" value="P:valyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07962">
        <property type="entry name" value="Anticodon_Ia_Val"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00817">
        <property type="entry name" value="ValRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000020">
        <property type="entry name" value="Valine--tRNA ligase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.740.10:FF:000005">
        <property type="entry name" value="Valine--tRNA ligase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000236">
        <property type="entry name" value="Valine-tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="entry name" value="Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02004">
        <property type="entry name" value="Val_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033705">
        <property type="entry name" value="Anticodon_Ia_Val"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002303">
        <property type="entry name" value="Valyl-tRNA_ligase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004349">
        <property type="entry name" value="PRK05729.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00422">
        <property type="entry name" value="valS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946:SF109">
        <property type="entry name" value="VALINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946">
        <property type="entry name" value="VALYL-TRNA SYNTHETASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00986">
        <property type="entry name" value="TRNASYNTHVAL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="11">
        <location>
            <begin position="49"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="12">
        <location>
            <begin position="731"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="12">
        <location>
            <begin position="822"/>
            <end position="917"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG94816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1057" mass="124815" checksum="CDA59D50EF7BB393" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQY0</accession>
    <name>A0A1J1GQY0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA polymerase delta interacting protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00209500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527513.1">
        <property type="nucleotide sequence ID" value="XM_028670796.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQY0"/>
    <dbReference type="GeneID" id="39730622"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00209500"/>
    <dbReference type="OMA" id="RSYYDIF"/>
    <dbReference type="OrthoDB" id="1856718at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF10">
        <property type="entry name" value="NADPH-DEPENDENT DIFLAVIN OXIDOREDUCTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="7">
        <location>
            <begin position="9"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="792" mass="95907" checksum="A5A4FEFFE393B30C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQZ7</accession>
    <name>A0A1J1GQZ7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FMR1-interacting protein 1 conserved domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00233400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527750.1">
        <property type="nucleotide sequence ID" value="XM_028671059.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQZ7"/>
    <dbReference type="GeneID" id="39730861"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00233400"/>
    <dbReference type="OMA" id="LNKMPEH"/>
    <dbReference type="OrthoDB" id="273070at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019496">
        <property type="entry name" value="NUFIP1_cons_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10453">
        <property type="entry name" value="NUFIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMR1-interacting protein 1 conserved" evidence="1">
        <location>
            <begin position="397"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="574" mass="69198" checksum="8EBBBC5D99D7D087" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR51</accession>
    <name>A0A1J1GR51_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00230200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527719.1">
        <property type="nucleotide sequence ID" value="XM_028671025.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR51"/>
    <dbReference type="GeneID" id="39730829"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00230200"/>
    <dbReference type="OMA" id="NGNLPYE"/>
    <dbReference type="OrthoDB" id="370860at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="154"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="549" mass="64923" checksum="95D99605AFDB0465" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR56</accession>
    <name>A0A1J1GR56_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00234600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527762.1">
        <property type="nucleotide sequence ID" value="XM_028671072.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR56"/>
    <dbReference type="GeneID" id="39730874"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00234600"/>
    <dbReference type="OrthoDB" id="381988at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="245" mass="29298" checksum="8588AA4D32F69F78" modified="2017-02-15" version="1">MEYLSKFYIKHIEKKSEDEFYDDKVRKIKMKNCCKKWSNSMNNKNIMIDYKKEIYESSFLKNMEKVWSLFFNEDKKGKLLLHKEEENIYSLPNFLIIDNINNNTCNNKNNNTNNNKCDDNLILDENDDEKISTNKNIYLNKKFIDIYHKHDHSYSFYHKEIDDFLILPDILTNYNEEINAIKIYDENFNMKSNLIISKNELSEDDSGNNNINEKVKTKFSNNSIINNENENENIISSKDLNIMTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRD6</accession>
    <name>A0A1J1GRD6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00223300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527651.1">
        <property type="nucleotide sequence ID" value="XM_028670949.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRD6"/>
    <dbReference type="GeneID" id="39730760"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00223300"/>
    <dbReference type="OMA" id="KHEQLFF"/>
    <dbReference type="OrthoDB" id="186625at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36812:SF9">
        <property type="entry name" value="MYB-LIKE PROTEIN X ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36812">
        <property type="entry name" value="NEUROFILAMENT TRIPLET M PROTEIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012610883" description="EF-hand domain-containing protein" evidence="4">
        <location>
            <begin position="22"/>
            <end position="1133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="510"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="610"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="720"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="747"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="843"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="877"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="1006"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="263"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="75"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="263"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="312"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG94836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1133" mass="134075" checksum="5D4C2D5A170CA724" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRM1</accession>
    <name>A0A1J1GRM1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Patatin-like phospholipase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00164500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526757.1">
        <property type="nucleotide sequence ID" value="XM_028675202.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730170"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00164500"/>
    <dbReference type="OMA" id="HYNADFF"/>
    <dbReference type="OrthoDB" id="630895at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004620">
        <property type="term" value="F:phospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185:SF1">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3 4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="7">
        <location>
            <begin position="1159"/>
            <end position="1408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="540"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1787"/>
            <end position="1837"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="633"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="4">
        <location>
            <begin position="1163"/>
            <end position="1168"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="4">
        <location>
            <begin position="1195"/>
            <end position="1199"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="4">
        <location>
            <begin position="1395"/>
            <end position="1397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="547"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1797"/>
            <end position="1836"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="1197"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="1395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1947" mass="233802" checksum="92668031DA16691D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRQ5</accession>
    <name>A0A1J1GRQ5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Acyl CoA:diacylglycerol acyltransferase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00168350</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526797.1">
        <property type="nucleotide sequence ID" value="XM_028670002.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRQ5"/>
    <dbReference type="GeneID" id="39730210"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00168350"/>
    <dbReference type="OMA" id="KINIYQR"/>
    <dbReference type="OrthoDB" id="10039049at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004299">
        <property type="entry name" value="MBOAT_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014371">
        <property type="entry name" value="Oat_ACAT_DAG_ARE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10408">
        <property type="entry name" value="STEROL O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10408:SF9">
        <property type="entry name" value="STEROL O-ACYLTRANSFERASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03062">
        <property type="entry name" value="MBOAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000439">
        <property type="entry name" value="Oat_ACAT_DAG_ARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="171"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="206"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="287"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="315"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG93976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="337" mass="40736" checksum="BE5314506AEB2D47" modified="2017-02-15" version="1">MKIRVQSNTISEIEQKYYIEKLYVNINNDNKNNNDLNKHEKNEVKEQDNNIQKNLYTPSHLDIFDNNSPIMSSNFCGFGNLILNMGLFFSLIMPLLNFMEKGYFLDTSMHSYLFTNLEYAKRYPDDYFIKYKIISLKNYINFMICPSLIYKFNFKRIKKFRPKYFVQKITSLLLTVIIEYTTFTVFIAPTIYHINNISFFEAIIRLIFPCLIIFLVTFYMIFECICNLFAEITKFGEREFYQDWWNSTIWYEFSRKWNNVVQVWLFKHVYLVAKNNYKIACFHTCKFYLFFLMFLQFPLSWLGEHFYKNKPIGNIIFWSNILLGLPLIFISYANEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRX2</accession>
    <name>A0A1J1GRX2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA polymerase sigma-70 region 3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00149400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526608.1">
        <property type="nucleotide sequence ID" value="XM_028675037.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRX2"/>
    <dbReference type="GeneID" id="39730018"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00149400"/>
    <dbReference type="OMA" id="FENSIYM"/>
    <dbReference type="OrthoDB" id="392298at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050239">
        <property type="entry name" value="Sigma-70_RNA_pol_init_factors"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30603">
        <property type="entry name" value="RNA POLYMERASE SIGMA FACTOR RPO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30603:SF47">
        <property type="entry name" value="RNA POLYMERASE SIGMA FACTOR SIGD, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="Sigma3 and sigma4 domains of RNA polymerase sigma factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="28"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="188"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="422"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="812" mass="97191" checksum="F8BBEDEAEFBCFFDD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRX3</accession>
    <name>A0A1J1GRX3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glycerol kinase</fullName>
            <ecNumber evidence="3">2.7.1.30</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP:glycerol 3-phosphotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00262700</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the FGGY kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.30" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528034.1">
        <property type="nucleotide sequence ID" value="XM_028671375.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRX3"/>
    <dbReference type="GeneID" id="39731156"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00262700"/>
    <dbReference type="OMA" id="FMLMNIG"/>
    <dbReference type="OrthoDB" id="5422795at2759"/>
    <dbReference type="UniPathway" id="UPA00618">
        <property type="reaction ID" value="UER00672"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004370">
        <property type="term" value="F:glycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046167">
        <property type="term" value="P:glycerol-3-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006641">
        <property type="term" value="P:triglyceride metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07792">
        <property type="entry name" value="ASKHA_NBD_FGGY_GK1-3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000086">
        <property type="entry name" value="Glycerol kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018483">
        <property type="entry name" value="Carb_kinase_FGGY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="FGGY_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042018">
        <property type="entry name" value="GK1-3_metazoan-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000756">
        <property type="entry name" value="PRK00047.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10196:SF69">
        <property type="entry name" value="GLYCEROL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10196">
        <property type="entry name" value="SUGAR KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000538">
        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00933">
        <property type="entry name" value="FGGY_KINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00445">
        <property type="entry name" value="FGGY_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="6 10 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbohydrate kinase FGGY N-terminal" evidence="11">
        <location>
            <begin position="3"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="Carbohydrate kinase FGGY C-terminal" evidence="12">
        <location>
            <begin position="262"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00043149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG95222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="501" mass="56914" checksum="CB66F4DFD3C893D5" modified="2017-02-15" version="1">MNIILSIDQSTQSTKLVFFDEELNVLHMNNLPHEQKCFKPGWYEHDPIEIMDNLYKLMNEGANSLKEKYKNIVIKCIGITNQRETVIIWDKFTGKPLYNAIVWLDTRVEDMVAEFSEKYNNDDFQKKTGTYFNTYFSAFKILWLIQNNEIIKQKVSDGTAMIGNINTWLIYNLTKGQCYTDVTNASRTLLMDIKTLQWDEKLCRIFGITNMNSLPEIKNNCTNFGLVKNELVPDYLNVPITGCIGDQQSACIGQAIFDEGEAKCTYGTGVFLLINTGNKIVYSSCGLITTVCYKFNEDDEPNYALEGSIGTAGSGVSWLIKNNLINDPSDTNDIMEKYEDTGGVTFVPAFSGLYAPRWRPDARASICGMTFNTDKNQIVRSLLEGIVFQLNEIVYSLISDMGIEMLHVLRCDGGMTKNKAFMQFNSDIINTKIEVSKYKEVTALGAAVLAGLGVKIWKDLDSVKRLLRASDSVYHCKMEDKKRKKKIIEWNKAVERNLLHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRY9</accession>
    <name>A0A1J1GRY9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PIR-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00264300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528050.1">
        <property type="nucleotide sequence ID" value="XM_028671393.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRY9"/>
    <dbReference type="GeneID" id="39731172"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00264300"/>
    <dbReference type="OMA" id="RLHEMEM"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="284"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="381" mass="42310" checksum="B03B0AA1C2DA5365" modified="2017-02-15" version="1">MMTIYIYFLVCIFQYFYSINFEIGKNNLKKELSLRSERILAEEQQIRRIRNVRSTSEIKSSLKSWLDSIQDGLFDELDQLTNNFTVTNVRKFSQWMHNKGGIITRALNLVPDPDTKSFLNDTLTSWRRLTDEVLVNSAIESYVDSILYPANIITNNNGSSSTYALSSIIQSTSTSLPTPTESTNITTLPISTSSPESTVSPTTALPSTIDLSSTISLSPTTSSDSHINSTTPFINNISESSTVLSTNETNTTTALTINSVSVTPVNNSGGITSATCTGLLCGPAFVALPVSVALLGGVFFFVLLYKYTPVGKFLGRDSPKKKKGKKRLNEMPMERINSPKLLKVEKTENVKRSRLHRFLRAFGYDKNFPYIDEDIPSDQVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS06</accession>
    <name>A0A1J1GS06_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">CDGSH iron-sulfur domain-containing protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00002000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528066.1">
        <property type="nucleotide sequence ID" value="XM_028671411.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS06"/>
    <dbReference type="GeneID" id="39728542"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00002000"/>
    <dbReference type="OMA" id="HKVFIEN"/>
    <dbReference type="OrthoDB" id="449252at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.90">
        <property type="entry name" value="CDGSH iron-sulfur domain, mitoNEET-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018967">
        <property type="entry name" value="FeS-contain_CDGSH-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042216">
        <property type="entry name" value="MitoNEET_CISD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09360">
        <property type="entry name" value="zf-CDGSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00704">
        <property type="entry name" value="ZnF_CDGSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Iron-binding zinc finger CDGSH type" evidence="6">
        <location>
            <begin position="27"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="151" mass="18002" checksum="5C03F3F83C35DCF6" modified="2017-02-15" version="1">MSDPLEYLNKINFNTNKFPQYTHLIETCPSEHEKEKVIRICRCWQSGKFPYCDDTHKIFIENGDNVGPYVAKLVSYKLSDEEKLKKQKYNEKYIKMDNKFLSEKSTKLNFKLKYSFMNHKLRKSIFLSFFVLTSALLYTKKDQVTNIYSAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS31</accession>
    <name>A0A1J1GS31_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Plasmodium RESA N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00264000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528047.1">
        <property type="nucleotide sequence ID" value="XM_028671390.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS31"/>
    <dbReference type="GeneID" id="39731169"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00264000"/>
    <dbReference type="OrthoDB" id="10534635at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="232" mass="28607" checksum="1D69391013B18C6D" modified="2017-02-15" version="1">MEFHNTQKNDLFKAKWTSKKAYLKLCALHFYGIQKKEYKKNYSKLFLYKLFKVLFISLLYTFLEYICESGDKITLAYQYSKYHMRTLVEKKKNETYFKEIQQNENFNKIWENCIENWRIQVFFMNSEFLVEWILFCSMNNVKEECKNEWWGKWIEEITDKVKSKYDRDNCDYEKNKGGRCSLERFNNFLEMKKRSFREFKIIHSNLWKKFLGDCEENLRKTKELENASEEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS54</accession>
    <name>A0A1J1GS54_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cullin-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00158300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2 3">Belongs to the cullin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526696.1">
        <property type="nucleotide sequence ID" value="XM_028675135.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS54"/>
    <dbReference type="GeneID" id="39730108"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00158300"/>
    <dbReference type="OMA" id="LCHEQMR"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1310.10">
        <property type="entry name" value="Cullin Repeats"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.130">
        <property type="entry name" value="Cullin, Chain C, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045093">
        <property type="entry name" value="Cullin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059120">
        <property type="entry name" value="Cullin-like_AB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016158">
        <property type="entry name" value="Cullin_homology"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036317">
        <property type="entry name" value="Cullin_homology_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001373">
        <property type="entry name" value="Cullin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019559">
        <property type="entry name" value="Cullin_neddylation_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11932">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00888">
        <property type="entry name" value="Cullin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26557">
        <property type="entry name" value="Cullin_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00182">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00884">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75632">
        <property type="entry name" value="Cullin homology domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50069">
        <property type="entry name" value="CULLIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cullin family profile" evidence="4">
        <location>
            <begin position="635"/>
            <end position="877"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="998" mass="120073" checksum="AD51DAE4591F014B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS98</accession>
    <name>A0A1J1GS98_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00013800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528180.1">
        <property type="nucleotide sequence ID" value="XM_028671538.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS98"/>
    <dbReference type="GeneID" id="39728660"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00013800"/>
    <dbReference type="OMA" id="CRTCKYV"/>
    <dbReference type="OrthoDB" id="378648at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="222" mass="26022" checksum="BEFABFA791F01B76" modified="2017-02-15" version="1">MSSNFLNENEDEINNILGEKYRSILKLKASNNIMNSEKLNINHKQTNENDESNNNDSLNKKLNLSGQHKRLYDFYNNKNSFQHYLKKLKTRRIDADGFRNILEKHLAYECENPMFKAFQDEDKKGIGSETNSSSSNHEGLHFYRKINLFNKNRSKSKNKSRKRKRITSKIDKKFIIKCRACKFINSNGFKIEDYYICQNCGDNDFSVIRSSSPNNMSSSMDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSD9</accession>
    <name>A0A1J1GSD9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Syntaxin, Qa-SNARE family, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00014400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528186.1">
        <property type="nucleotide sequence ID" value="XM_028671545.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSD9"/>
    <dbReference type="GeneID" id="39728666"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00014400"/>
    <dbReference type="OMA" id="HPRNAPQ"/>
    <dbReference type="OrthoDB" id="10255013at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048278">
        <property type="term" value="P:vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15848">
        <property type="entry name" value="SNARE_syntaxin1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006011">
        <property type="entry name" value="Syntaxin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF307">
        <property type="entry name" value="PROTEIN SSO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14523">
        <property type="entry name" value="Syntaxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00503">
        <property type="entry name" value="SynN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="289"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="7">
        <location>
            <begin position="217"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="313" mass="36628" checksum="D18DAA9968453D74" modified="2017-02-15" version="1">MIDLFDKVKTSAISKNKQNAKQMMQTLIFKNDIIIDNVDINEDTIINVFNEKNNDLKIYVDTVDKIKQEIQKINSNVSEISSLKNKINISITVEEENELSLHLNTLIKNTNEIIQSIKIDIRNLRKKFILKTQENRAIKKDIYDNLINIFKKSLHSYQHIQNVFHHSMKDKISRHIKIIYPNYSDEDVNYVLNHDDVNTQILVKWKLQGHEDLKNALTDVETKYKDVKTLEKSVYDLHQTIIELSALIEMNDEVIDNIHENIKDAQIFTEKANVDLIEARNIQRKTSKWMCYITIGIVVVIIIICVPILVKFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSJ6</accession>
    <name>A0A1J1GSJ6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Microtubule-associated protein Jupiter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00020900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528250.1">
        <property type="nucleotide sequence ID" value="XM_028671615.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSJ6"/>
    <dbReference type="GeneID" id="39728731"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00020900"/>
    <dbReference type="OMA" id="NPEMNKM"/>
    <dbReference type="OrthoDB" id="10258955at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="91" mass="9878" checksum="1E28C19E86DC21E1" modified="2017-02-15" version="1">MDVKDNPFIRNRSSTRITNAPGGNSSVSFGNYIDTENKKISDKNEKNNLNHNKNVRAAGNLEASKMPSETDKKTNVKVNQPPGGASSIIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSS5</accession>
    <name>A0A1J1GSS5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Activator of Hsp90 ATPase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00007900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AHA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528123.1">
        <property type="nucleotide sequence ID" value="XM_028671474.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSS5"/>
    <dbReference type="GeneID" id="39728601"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00007900"/>
    <dbReference type="OMA" id="RNGWTEN"/>
    <dbReference type="OrthoDB" id="567237at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08892">
        <property type="entry name" value="SRPBCC_Aha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013538">
        <property type="entry name" value="ASHA1/2-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08327">
        <property type="entry name" value="AHSA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Activator of Hsp90 ATPase homologue 1/2-like C-terminal" evidence="2">
        <location>
            <begin position="11"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="140" mass="16448" checksum="50A924727D5818CA" modified="2017-02-15" version="1">MNFEIQEEYYVPSEVLFNIFVDPSTLTRLSRGSLAEVELKVGGKFTLFSGSIYGEFVEIQKPQKIVQKWKFCDWKDSDYSIVTLEFINIKENHTLLKLKHENIPLTNKYNEGGVLERCKYGWTENFLRNIEIILGYPKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT60</accession>
    <name>A0A1J1GT60_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00188600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000026">
        <property type="protein sequence ID" value="CRG94491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527309.1">
        <property type="nucleotide sequence ID" value="XM_028670570.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT60"/>
    <dbReference type="GeneID" id="39730413"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00188600"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="276" mass="33397" checksum="AE29BD0A429F13E3" modified="2017-02-15" version="1">MKTLILYLKITTFLLLIWIYQCFYNCDSYKTLIDKNILQTKNELKYERVLTEGDIEAKRQAYAEGCPKECSLDNKKNKCEDPFPYENPCDHWHKGIAPQLWELFDKETSGMDPKWRDQKWNNEWNKISAKKVNDLPSIYDQQDISEEEKKKKIDSVKRELILEFMKFLDECKKEMRDNKTESECKNKMRNNRTESECMKEMRENNTECESKKEIRDNKIESEFMKEIKDNKTEFDFKKEMRDNETESESKNEQGKNKMKNKKANILKFLFKRFDNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTH1</accession>
    <name>A0A1J1GTH1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Delta-aminolevulinic acid dehydratase</fullName>
            <ecNumber evidence="8">4.2.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00199400</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>2 5-aminolevulinate = porphobilinogen + 2 H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58126"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="4.2.1.24"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homooctamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the ALAD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.24" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTH1"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00199400"/>
    <dbReference type="OMA" id="YMDIIWR"/>
    <dbReference type="OrthoDB" id="952271at2759"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00318"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004655">
        <property type="term" value="F:porphobilinogen synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001731">
        <property type="entry name" value="ALAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030656">
        <property type="entry name" value="ALAD_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006762">
        <property type="entry name" value="PRK09283.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11458">
        <property type="entry name" value="DELTA-AMINOLEVULINIC ACID DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11458:SF0">
        <property type="entry name" value="DELTA-AMINOLEVULINIC ACID DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00490">
        <property type="entry name" value="ALAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00144">
        <property type="entry name" value="DALDHYDRTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01004">
        <property type="entry name" value="ALAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00169">
        <property type="entry name" value="D_ALA_DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="4 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 8" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012498245" description="Delta-aminolevulinic acid dehydratase" evidence="11">
        <location>
            <begin position="18"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG94598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="448" mass="53338" checksum="C3C42CE0263FC925" modified="2017-02-15" version="1">MNSLVLIFICVHNLVYCLNRNIRKNAYILYSPKSANSIKPTSRRWSKPLNNNNSHNINEGEKSTEDFYNKNIDNHYNLKNFSKDVNNNIYIETNRRERRIKRNKYLLSLYNNTNIKTSNFIYPLFIHEEEVEKKKTKLDGIYTYNYEGIIKEIEECLKLNIHHFMFFPVVNEEKKSVYCEECYNENSYFCKTISKIKEKYLDDIVIYVDVALDPYNIYGHDGIYDEKKREIINDISVHTLVKQSLCLAKSGADVVCPSDSMDNRIEKIRKNLDFYDFRHILILSYTCKYSSCLYKPFRSILNSNISKNFVKNKQSYQHDFNSYIDLNNVEKHIKEGADIIMVKPSMFYLDIIEKIRNRIRDNVNVPIAVYNVSGEYMMIKNYVKYLNENINYENEILTELFKSYLRAGANIIITYFSKQYGIYMKNLYEKNIKIEDNFNNNFNIELTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTJ3</accession>
    <name>A0A1J1GTJ3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">TMEM121 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00407500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TMEM121 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527192.1">
        <property type="nucleotide sequence ID" value="XM_028670440.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTJ3"/>
    <dbReference type="GeneID" id="39732605"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00407500"/>
    <dbReference type="OMA" id="QFIGYII"/>
    <dbReference type="OrthoDB" id="391274at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032776">
        <property type="entry name" value="CECR6/TMEM121"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14997">
        <property type="entry name" value="CECR6_TMEM121"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="69"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="177"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="445"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="493"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="523"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="565"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="700"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="733"/>
            <end position="755"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="815" mass="97154" checksum="ACD93F36213684FB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTK8</accession>
    <name>A0A1J1GTK8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Apicoplast 1-acyl-sn-glycerol-3-phosphate, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00203500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527453.1">
        <property type="nucleotide sequence ID" value="XM_028670729.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTK8"/>
    <dbReference type="GeneID" id="39730561"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00203500"/>
    <dbReference type="OMA" id="FYPTPGM"/>
    <dbReference type="OrthoDB" id="417078at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003841">
        <property type="term" value="F:1-acylglycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006654">
        <property type="term" value="P:phosphatidic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07989">
        <property type="entry name" value="LPLAT_AGPAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10434">
        <property type="entry name" value="1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10434:SF11">
        <property type="entry name" value="1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="20"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="4">
        <location>
            <begin position="97"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="292" mass="33843" checksum="3B9BD4E1E6DE22C4" modified="2017-02-15" version="1">MENNEEKKEQKTNFYFRLIISFHIFMLMLISLVISLCFQLISCVLFLPLLIYSKRIRLIILGASFKCCCYFVCSPLNPFWKVKVIRKCKKNYKPTKTLLFINHLSAVDPWVITSCILPWEMKFAFKSTLFRIPIAGQSLYLSGDIPVYFSKGRGGWEVKPESKEKLMKTCKEYSDLKIGIAVFPEGTRSLSGQLQLFKSGFFKFAIENNCEILPCALHGSNKAWPIKSKLLDKGTMYFSFGEPFYPTPGMTYQELMDKTRKAIFDLIKEFPDYDPEKDKLLNEYPQVRGHGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTM9</accession>
    <name>A0A1J1GTM9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peripheral plastid protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00309800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528694.1">
        <property type="nucleotide sequence ID" value="XM_028672108.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTM9"/>
    <dbReference type="GeneID" id="39731631"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00309800"/>
    <dbReference type="OMA" id="LQSNYNC"/>
    <dbReference type="OrthoDB" id="1597724at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="427"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="160"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="523" mass="62534" checksum="CD51019742A0E519" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTN4</accession>
    <name>A0A1J1GTN4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">2-(3-amino-3-carboxypropyl)histidine synthase subunit 1</fullName>
            <ecNumber evidence="3 11">2.5.1.108</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00285400</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>L-histidyl-[translation elongation factor 2] + S-adenosyl-L-methionine = 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + S-methyl-5'-thioadenosine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36783"/>
            <dbReference type="Rhea" id="RHEA-COMP:9748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9749"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:29979"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73995"/>
            <dbReference type="EC" id="2.5.1.108"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="11">Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 11">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the DPH1/DPH2 family. DPH1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.108" evidence="3 11"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528465.1">
        <property type="nucleotide sequence ID" value="XM_028671853.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTN4"/>
    <dbReference type="GeneID" id="39731387"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00285400"/>
    <dbReference type="OMA" id="CNALEGM"/>
    <dbReference type="OrthoDB" id="1649088at2759"/>
    <dbReference type="UniPathway" id="UPA00559"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090560">
        <property type="term" value="F:2-(3-amino-3-carboxypropyl)histidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11840:FF:000001">
        <property type="entry name" value="2-(3-amino-3-carboxypropyl)histidine synthase subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11860:FF:000002">
        <property type="entry name" value="2-(3-amino-3-carboxypropyl)histidine synthase subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11840">
        <property type="entry name" value="Diphthamide synthesis DPH1/DPH2 domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11850">
        <property type="entry name" value="Diphthamide synthesis DPH1/DPH2 domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11860">
        <property type="entry name" value="Diphthamide synthesis DPH1/DPH2 domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016435">
        <property type="entry name" value="DPH1/DPH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042263">
        <property type="entry name" value="DPH1/DPH2_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042264">
        <property type="entry name" value="DPH1/DPH2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042265">
        <property type="entry name" value="DPH1/DPH2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035435">
        <property type="entry name" value="DPH1/DPH2_euk_archaea"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00322">
        <property type="entry name" value="diphth2_R"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10762:SF1">
        <property type="entry name" value="2-(3-AMINO-3-CARBOXYPROPYL)HISTIDINE SYNTHASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10762">
        <property type="entry name" value="DIPHTHAMIDE BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01866">
        <property type="entry name" value="Diphthamide_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004967">
        <property type="entry name" value="DPH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00032">
        <property type="entry name" value="Radical_SAM_3-amino-3-carboxyp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR004967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG95657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="468" mass="55154" checksum="6E1FA455F58AD639" modified="2017-02-15" version="1">MNEITLKDKINEQKKVQCSIPKFILNNEILKRAIKKSLPENYNFEVYKCIDIILKEKYKNIVLQLPEGLLIWGLYLSELFYFFCDCVEEVIILGDVTYGGCCIDDFTSDKLKCDLIIHYGHSCLIPLTVTKIRCIYVFVDIKLNSSHLVKTIKKNFNKKDIILLLGTIQFSCIIHSVHNILKTENYFDTFLPIPQVLPLTKGEVLGCTSPNLYLFLYEQVIKKKKETENNEIETNLCKNIEIKSNINENNESYIINECRKFLKENNIKIIFIADGRFHLESLMIHNPDFSFYRYNPFDKVLSEEKYDYKLFYEIRKNEIKKCINCKTVCIILSTLGRQGNVNILKNIISILKEKNIYFFILLLSEIFNEKLQLFKNVDVFIQIGCPRLSIDWGNYNLKPLLNTYEAYVLLKSVKYREIYPMDYYSHSGNEWSNYNAGIGDVNEKYLTTKEIIKRRIQLRKNKINIHYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTR6</accession>
    <name>A0A1J1GTR6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Kelch protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00311300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528708.1">
        <property type="nucleotide sequence ID" value="XM_028672124.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTR6"/>
    <dbReference type="GeneID" id="39731646"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00311300"/>
    <dbReference type="OMA" id="NENRAYH"/>
    <dbReference type="OrthoDB" id="10251809at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="250"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1070"/>
            <end position="1110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="61"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="255"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1084"/>
            <end position="1096"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1133" mass="134465" checksum="6A1194807CC19CFB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTZ5</accession>
    <name>A0A1J1GTZ5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00316700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528762.1">
        <property type="nucleotide sequence ID" value="XM_028672183.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTZ5"/>
    <dbReference type="GeneID" id="39731700"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00316700"/>
    <dbReference type="OMA" id="WPKDSLF"/>
    <dbReference type="OrthoDB" id="370721at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="308" mass="37552" checksum="1A4283F18970F937" modified="2017-02-15" version="1">MSRYYSFIIIFFNVLNEVIFVKSIKMNQLPFKLNERITIKHLQILHLYSLNYKQHKIYTYIKRPLLHINQRKLSYLKSNKNIYSKYYNNEPIYSTYNPILNYDVLDLIKVYGRLAEHSNYESLNIIINVNGEKKKKYSDLFKNFFFFFKNNDHNNYNKVLWFDHFSKYGKMNFTDFKNSLLKLRFKWPKDSLFPTYNIFLFEKGLSKNMDSPLIRKKVEKYIQHQEINEDVLKSCFYCFSSGKEYITADDILNTFNEWKENDKKKKKDDKKKSFSFFKKYNNTNDSIDWFTFKNNIDLCTIKLHESKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU00</accession>
    <name>A0A1J1GU00_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00218700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527605.1">
        <property type="nucleotide sequence ID" value="XM_028670898.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU00"/>
    <dbReference type="GeneID" id="39730714"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00218700"/>
    <dbReference type="OMA" id="YCKNDKQ"/>
    <dbReference type="OrthoDB" id="382895at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="340" mass="40526" checksum="6498BD6DBAE71570" modified="2017-02-15" version="1">MKNMVKNRKEKESHISDDSKKEKNERKEISKIKLIFVNIYKMVKKKIKSKHKYSFFMGIFIVFLICSGFFQILTELYHTHFYNFKYIDVSNTEKLKEVFFNNTPYLVYCKNSKHKSIHPVINSSRLNYPDILNVAIINCKSLLPSQQNIYQRFNLDESIPAFIISYGKKPKPISLNILNNKKKFLSFIRDSLVFSVPLFSKFPQFQTKCLNQNKKCILFISSKNLIRSNIKYNYINDIFINNKYFSINPMIIDSSRFQLKLNDEIFTSYSKNKDIHVLCLFNHHKDKIDEYYGYFYKDNFEDFKKLSNFVLSCMNATNESSQVIKLSNTPKIKYRTYKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU40</accession>
    <name>A0A1J1GU40_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fam-i protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00324100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000051">
        <property type="protein sequence ID" value="CRG96028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528836.1">
        <property type="nucleotide sequence ID" value="XM_028672267.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU40"/>
    <dbReference type="GeneID" id="39731774"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00324100"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="103"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="225" mass="26435" checksum="82CE9DFE4D340E0E" modified="2017-02-15" version="1">MDLNPSDPININSNKRLNEGDSTAGFAHRVIKDATVSIPENPLHHNLNSRDAIQNPSKHINLDSATSINLLDKKSLSIFKLVIIIISFLRFAKILDNSNKKVKDDFEKEMQKEKKKMEDGQKKLLEKKKKIEAREKIILKGKEEWEKKTLKEKQLCGPDMLKQLEEWENRVINKGEVWKKRMLRKKAKLEMKMLKNKEEGDKRMLKVIEKFEKKMQKEKESEKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU96</accession>
    <name>A0A1J1GU96_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase subunit, putative</fullName>
            <ecNumber evidence="8">2.7.7.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00332000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528910.1">
        <property type="nucleotide sequence ID" value="XM_028672349.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU96"/>
    <dbReference type="GeneID" id="39731850"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00332000"/>
    <dbReference type="OMA" id="LGPTLWW"/>
    <dbReference type="OrthoDB" id="10256606at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006384">
        <property type="term" value="P:transcription initiation at RNA polymerase III promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04330">
        <property type="entry name" value="RNAP_III_Rpc25_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.120">
        <property type="entry name" value="RNA polymerase Rpb7-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013238">
        <property type="entry name" value="RNA_pol_III_Rbc25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036898">
        <property type="entry name" value="RNA_pol_Rpb7-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045113">
        <property type="entry name" value="Rpb7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005576">
        <property type="entry name" value="Rpb7-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II, III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709:SF1">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08292">
        <property type="entry name" value="RNA_pol_Rbc25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03876">
        <property type="entry name" value="SHS2_Rpb7-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88798">
        <property type="entry name" value="N-terminal, heterodimerisation domain of RBP7 (RpoE)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNA polymerase Rpb7-like N-terminal" evidence="6">
        <location>
            <begin position="8"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase III subunit Rpc25" evidence="7">
        <location>
            <begin position="83"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="186" mass="22072" checksum="462F2006CEB1EF20" modified="2017-02-15" version="1">MFSLFRIEDVLNIEAHFKDEEIKSVIEFLLRAKYIDKVLQNVGFCVGLYDILEIKNKEILIGSGEIRFKVIFRLVFFQPFENEIIEGYVKSSDYNGIIISLGFFENIRVNCANLREPKEFDEEKKEWYWNYEGIKFFYTKNELIRVRILDTYFSDPNEMNKDESIPSMSITATVQQDGLGLVKWWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUA9</accession>
    <name>A0A1J1GUA9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00328200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000056">
        <property type="protein sequence ID" value="CRG96069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528874.1">
        <property type="nucleotide sequence ID" value="XM_028672308.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731812"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00328200"/>
    <dbReference type="OMA" id="HWNEERI"/>
    <dbReference type="OrthoDB" id="383264at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="688"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="257"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="396"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="440"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1051"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1151"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1359"/>
            <end position="1393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="257"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="284"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="311"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="400"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="444"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1583" mass="186056" checksum="E1EBDB1D54D117D7" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUH0</accession>
    <name>A0A1J1GUH0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metabolite/drug transporter, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00332100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528911.1">
        <property type="nucleotide sequence ID" value="XM_028672350.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUH0"/>
    <dbReference type="GeneID" id="39731851"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00332100"/>
    <dbReference type="OMA" id="RKWHINI"/>
    <dbReference type="OrthoDB" id="541403at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06174">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23525:SF1">
        <property type="entry name" value="NODULIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23525">
        <property type="entry name" value="TRANSPORTER, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="300"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="364"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="392"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="417" mass="49224" checksum="9B0AC25ACADC56D4" modified="2017-02-15" version="1">MKKWKEKRKWHINIILMFFYHFFDRINYSMRNTFLHDHYIYLKFQKNKIIGLLSIINSIVCLIISPIVGYYCDKHKKKRKKILQIISISYLLVNIIHFMFIRTNSLILIIFVTALSKMLHECCHVITESIFIESIDKGKKSLIFTYQKLISTVATTLGPFFCMILFYLYNDIWNIKNIFIIFQFSVLSILPQTFISFLWENDNINVVKNTEEIDLITKKKNQKNIFCFSSYHIPYIVFISHIITLAGAGMTFKYFSLFLKTEYKVSPMLMCILNIVIPVLLSIFTYISQKLSKRLGRAQVSLFFTSIGFLLLCSLSYLHNYKDVLKVHVFRSVFQNCTNSIDKSILYDFIDTNRDTGKWMGVQSLYYLVWSISAYFGGWLSDISSYRNTFKITTIFYLISLIIYTPLLWLVPIKETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUJ1</accession>
    <name>A0A1J1GUJ1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Threonylcarbamoyl-AMP synthase</fullName>
            <ecNumber evidence="3">2.7.7.87</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">L-threonylcarbamoyladenylate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">SUA5</name>
        <name evidence="14" type="ORF">PGAL8A_00318200</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-threonine + hydrogencarbonate + ATP = L-threonylcarbamoyladenylate + diphosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:36407"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="EC" id="2.7.7.87"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SUA5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.87" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528777.1">
        <property type="nucleotide sequence ID" value="XM_028672202.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUJ1"/>
    <dbReference type="GeneID" id="39731715"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00318200"/>
    <dbReference type="OMA" id="THYSPVV"/>
    <dbReference type="OrthoDB" id="412787at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061710">
        <property type="term" value="F:L-threonylcarbamoyladenylate synthase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006450">
        <property type="term" value="P:regulation of translational fidelity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.870.10:FF:000009">
        <property type="entry name" value="Threonylcarbamoyl-AMP synthase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.870.10">
        <property type="entry name" value="DHBP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11030">
        <property type="entry name" value="Threonylcarbamoyl-AMP synthase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006070">
        <property type="entry name" value="Sua5-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038385">
        <property type="entry name" value="Sua5/YwlC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005145">
        <property type="entry name" value="Sua5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050156">
        <property type="entry name" value="TC-AMP_synthase_SUA5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17490">
        <property type="entry name" value="SUA5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17490:SF16">
        <property type="entry name" value="THREONYLCARBAMOYL-AMP SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03481">
        <property type="entry name" value="Sua5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01300">
        <property type="entry name" value="Sua5_yciO_yrdC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="YrdC/RibB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51163">
        <property type="entry name" value="YRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 14" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="YrdC-like" evidence="13">
        <location>
            <begin position="14"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG95969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="549" mass="64289" checksum="D66F21C3DB54667A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUQ8</accession>
    <name>A0A1J1GUQ8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Folate transporter 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00343100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529018.1">
        <property type="nucleotide sequence ID" value="XM_028672469.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUQ8"/>
    <dbReference type="GeneID" id="39731961"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00343100"/>
    <dbReference type="OMA" id="SREYIFM"/>
    <dbReference type="OrthoDB" id="754047at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd17484">
        <property type="entry name" value="MFS_FBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000333">
        <property type="entry name" value="Folate transporter 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585:SF0">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03092">
        <property type="entry name" value="BT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="281"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="313"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="338"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="417"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="455" mass="51408" checksum="56881A491FB10433" modified="2017-02-15" version="1">MIEKSNNPYLSIDPIVDINKQNAEKLPLIDSTLKKNIDFTQLVVYLVGLSDGLTHLASLAIYYLFKDYFRLTPYQVSLILMYPYIPFILKPIIALITDSVSIFGMRRKPYLFLFSLFQSLNFLALAFLNLTVFQATIILFFISLCASFCTTVAEALVVESSIGKTYSQGTNKVTEFIASKAVGSLSVAYFSGYFLEKMPREYIFIATSVFPLIILVSCLFLKEKEYSTNKNIFNQLSDLIKFINTPIFLGPFLYIFVYMSGPDYDDIFFFFCTNKLGFRPSFMGTLRLTYGIASLIGIITYRVFLKNYSLKKTLIITTLISFPIYVSPIVLTEKINKFLGISNELFVLSGGFLIEAITEIQLLPLFILTANICQTGLEASVFATILSIKNLGSLTKKGTSSLLTYLMKIDSYNFDNLSIYILICGLFLLLSLCLVPLLPSEENIDKLKDKQKTYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUY6</accession>
    <name>A0A1J1GUY6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00326600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000053">
        <property type="protein sequence ID" value="CRG96051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528859.1">
        <property type="nucleotide sequence ID" value="XM_028672292.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUY6"/>
    <dbReference type="GeneID" id="39731797"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00326600"/>
    <dbReference type="OrthoDB" id="10583799at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="213" mass="24758" checksum="FEDEEF17362A3A4C" modified="2017-02-15" version="1" fragment="single">ESESRIEMTDNITESESIKGMIQNKTESEYKIEMTDNKSESESMKEMTDNKTESESMKMLIDNKTESESKIEMTDNKTESESRIEMTDNKTESESRIEMTDNITESESMKGMIDNKTESESKIEMTDNKTESESIKGMIENKTESESKIEMTDNKKESESIKEMTDNKTEAESRMEMTDNKTQSESKNEKGKNKIKNRKSNILKFLFKRFDNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV06</accession>
    <name>A0A1J1GV06_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00353500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529122.1">
        <property type="nucleotide sequence ID" value="XM_028672584.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV06"/>
    <dbReference type="GeneID" id="39732065"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00353500"/>
    <dbReference type="OMA" id="DSENIYY"/>
    <dbReference type="OrthoDB" id="8093034at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052462">
        <property type="entry name" value="SLIRP/GR-RBP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48027">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="6"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="90"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="442"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="574"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="126"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="151"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="186"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="255"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="286"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="331"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="345"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="362"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="377"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="574"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="592"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="606"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="635"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="647"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="662"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="675"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="705"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="739"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="771"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="787"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="798"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="833"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="849"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="887"/>
            <end position="896"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="923" mass="108577" checksum="40EEE792951492A7" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV36</accession>
    <name>A0A1J1GV36_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00331700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528907.1">
        <property type="nucleotide sequence ID" value="XM_028672346.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV36"/>
    <dbReference type="GeneID" id="39731847"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00331700"/>
    <dbReference type="OMA" id="FCYINNE"/>
    <dbReference type="OrthoDB" id="427280at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052842">
        <property type="entry name" value="ER_Co-chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45184">
        <property type="entry name" value="DNAJ PROTEIN ERDJ3A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45184:SF1">
        <property type="entry name" value="DNAJ PROTEIN ERDJ3A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13848">
        <property type="entry name" value="Thioredoxin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012995245" description="Thioredoxin domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="181"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="418" mass="49267" checksum="5C0BAF7AE6A71C9A" modified="2017-02-15" version="1">MKVYFLFFLFLLFCNTFYASILESIKHDLQIVNNQNFNTIVNKFRNEKVFVILFFKKTNKNIKNIIKDYNDVAIKYKGIITFCIADCDTNSSLCENELSLYVPNYKTSDSHYFLVYPVNPMPKFLFNEEVTESNIKKYTYLIPSKIEIIKDEKDLNVFISKHENMPKVLIFSNKKKPNYVLNALSNSFNKKLMFCYINNEMQDLVKKYNIKNFPSIIILKKNKVIDTYKGKHTYINIFDWLNIHSETFVLGGGFDISPDKSDEKPWKFELIPKFTKLSHGDICFKKADKGLCLIYLKEGEKLEKSEIDMLLSLKEKYKPHIDGRGINFRFMWIDIAMETNFRSLFEFNKYPSVVVFNPYKRIRYAKLNEDLIATQENIEKLLEKISGGDAKFTMLKGQVLPEFIQDNENNKTNEKDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV38</accession>
    <name>A0A1J1GV38_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00336400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528953.1">
        <property type="nucleotide sequence ID" value="XM_028672396.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV38"/>
    <dbReference type="GeneID" id="39731894"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00336400"/>
    <dbReference type="OMA" id="YAYFYNT"/>
    <dbReference type="OrthoDB" id="371720at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1178" mass="138569" checksum="1D02505231F9689B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV91</accession>
    <name>A0A1J1GV91_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Reticulocyte binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00363700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529218.1">
        <property type="nucleotide sequence ID" value="XM_028672691.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV91"/>
    <dbReference type="GeneID" id="39732167"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00363700"/>
    <dbReference type="OrthoDB" id="371050at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012023509" description="Reticulocyte binding protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="548" mass="65751" checksum="AE9D351378639E2B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVT4</accession>
    <name>A0A1J1GVT4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">guanylate cyclase</fullName>
            <ecNumber evidence="5">4.6.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Guanylyl cyclase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="primary">GCalpha</name>
        <name evidence="20" type="ORF">PGAL8A_00366100</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>GTP = 3',5'-cyclic GMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13665"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57746"/>
            <dbReference type="EC" id="4.6.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">In the C-terminal section; belongs to the adenylyl cyclase class-4/guanylyl cyclase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="14">In the N-terminal section; belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.2" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529241.1">
        <property type="nucleotide sequence ID" value="XM_028672716.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732191"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00366100"/>
    <dbReference type="OMA" id="CFTRIAN"/>
    <dbReference type="OrthoDB" id="354346at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140326">
        <property type="term" value="F:ATPase-coupled intramembrane lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004383">
        <property type="term" value="F:guanylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1230:FF:000026">
        <property type="entry name" value="Guanylyl cyclase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032631">
        <property type="entry name" value="P-type_ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF175">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16209">
        <property type="entry name" value="PhoLip_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13" id="KW-0141">cGMP biosynthesis</keyword>
    <keyword evidence="12 20" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="339"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="391"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1781"/>
            <end position="1808"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1820"/>
            <end position="1840"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1870"/>
            <end position="1892"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1904"/>
            <end position="1927"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1936"/>
            <end position="1960"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="1972"/>
            <end position="1996"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="2625"/>
            <end position="2642"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="2662"/>
            <end position="2683"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="2725"/>
            <end position="2753"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="2765"/>
            <end position="2785"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="3436"/>
            <end position="3460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="3472"/>
            <end position="3495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="3507"/>
            <end position="3532"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="19">
        <location>
            <begin position="2847"/>
            <end position="3020"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="19">
        <location>
            <begin position="3669"/>
            <end position="3803"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="762"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="2170"/>
            <end position="2379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="2951"/>
            <end position="2982"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="762"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="2951"/>
            <end position="2980"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00061340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00061677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00075861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="CRG96436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3925" mass="462068" checksum="BF4ECECB79B1FEFA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW38</accession>
    <name>A0A1J1GW38_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00370300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529283.1">
        <property type="nucleotide sequence ID" value="XM_028672763.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW38"/>
    <dbReference type="GeneID" id="39732233"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00370300"/>
    <dbReference type="OMA" id="PNDACKY"/>
    <dbReference type="OrthoDB" id="2143914at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="269" mass="32227" checksum="1A8FDF44E63685C9" modified="2017-02-15" version="1">MRIINFFFKSNISNCEEKGKNSPFHDINRTNNDSVIDVIKKIPINPFIDSNENLNKYKYDVEKKNIERFTGLKVYEEEDEKDHKKKQPIDYPFPISKNLVFQKNKVNKTDDRININYSNIVSDLYPEEGYKSPNRNKHFSSEWEILLAHNHGLYDFKNPDNNVIVNKDMYSLNTENDIRNKLNLYIERINVDNPNDACKYLAIEEYKCLLTHSFHMNPILSNQKCVKWFNEYMQCKWDEHKLNYGYNYIENRRNKKSKAYIAAPDYQYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWK3</accession>
    <name>A0A1J1GWK3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00428100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529505.1">
        <property type="nucleotide sequence ID" value="XM_028673009.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWK3"/>
    <dbReference type="GeneID" id="39732813"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00428100"/>
    <dbReference type="OrthoDB" id="370745at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032299">
        <property type="term" value="C:ribonuclease H2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013924">
        <property type="entry name" value="RNase_H2_suC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08615">
        <property type="entry name" value="RNase_H2_suC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="6"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="289" mass="34704" checksum="AADF8AAFD162ED8E" modified="2017-02-15" version="1">MNSFFCEDTEEEEKLLNNILKNTEDKLPETIEKIITSHLIKNDKENKKEELNIKSESSENIYTKKGNDENSIIDKYTNEEKINFNLETNIFSFHIKKNGKINADIFFIPYKSEDGKDIITKYAYNYDYYDIYSLNVENINKCIHSNKRKLEDNENCLNINKKIKIKKEIENESSYSKFSEQRRENFQKLLVHFRGRLFIGNSVIYSFFKTKTYLSMLHNNETNENKIEEFHFVDKKIQTYNLIKKATYWKQDEYPDISDTNIQKLLFFLIIPPLYNYKYEEELSSNIIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWM3</accession>
    <name>A0A1J1GWM3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cysteine desulfuration protein SufE, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00018200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SufE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528224.1">
        <property type="nucleotide sequence ID" value="XM_028671586.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWM3"/>
    <dbReference type="GeneID" id="39728704"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00018200"/>
    <dbReference type="OMA" id="CQSTVYI"/>
    <dbReference type="OrthoDB" id="411584at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003808">
        <property type="entry name" value="Fe-S_metab-assoc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43597:SF5">
        <property type="entry name" value="SUFE-LIKE PROTEIN 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43597">
        <property type="entry name" value="SULFUR ACCEPTOR PROTEIN CSDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02657">
        <property type="entry name" value="SufE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82649">
        <property type="entry name" value="SufE/NifU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="Fe-S metabolism associated" evidence="3">
        <location>
            <begin position="117"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="242" mass="28530" checksum="D212FD6BBC747567" modified="2017-02-15" version="1">MNKKKFKRIFFIFIHIICYFSILINSMNKRKNNKKTNFKIKRLILLKEKKLHKIKSNFILYIKNYELRNKKRKNNLNDIFNQLSGNKNHENLNIEHYNLTPKLKKTVQFFQSMPNNPYYKSQQVILLGKKCSPMPCEFKTRQNQVLGCQSTVYIYPNVELNENKKSIVWLGDSDGLLTKGIVYILIDGLSGYSPEEILKVNPNFITLTGISEFLTMSRINGYLNIMNKIKMFSTNILKNIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWX0</accession>
    <name>A0A1J1GWX0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit OST5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00463900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529862.1">
        <property type="nucleotide sequence ID" value="XM_028673406.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWX0"/>
    <dbReference type="GeneID" id="39733172"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00463900"/>
    <dbReference type="OMA" id="FHIFAFV"/>
    <dbReference type="OrthoDB" id="369557at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="83" mass="10003" checksum="804F7CC4D5DA92E3" modified="2017-02-15" version="1">MMSIKNLNVDLDPYDMLIERKYFPYFIYMFEIFSFISILILLDHQNVKREKRSIKLGIFLCFITAFNVGLSIFFILLYFNISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX17</accession>
    <name>A0A1J1GX17_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA N(3)-methylcytidine methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00468800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">S-adenosyl-L-methionine-dependent methyltransferase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the methyltransferase superfamily. METL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529910.1">
        <property type="nucleotide sequence ID" value="XM_028673460.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX17"/>
    <dbReference type="GeneID" id="39733221"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00468800"/>
    <dbReference type="OMA" id="DAQRNWD"/>
    <dbReference type="OrthoDB" id="417697at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026113">
        <property type="entry name" value="METTL2/6/8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22809">
        <property type="entry name" value="METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22809:SF5">
        <property type="entry name" value="TRNA N(3)-METHYLCYTIDINE METHYLTRANSFERASE METTL6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13489">
        <property type="entry name" value="Methyltransf_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037755">
        <property type="entry name" value="Mettl2_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR037755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="375" mass="44726" checksum="F85BAB3FB90511BC" modified="2017-02-15" version="1">MRPFYDSDIVVNFTLSEEAIQNEKRIIENNRIVVRDCHKQKLISEGKKNWDKFYNHYKTNFFKDRKWIKVEFDHIFKENLKYEKKNNHDIEMLKRDDEKDLKKKLILEIGCGVGNSLIPLLIEYHDFDFIGIDFSKNAINFLNEKWKKIVNINNKLKDEKLTGDTEDLLNNDLINVKKMVSHENNLLCDHIKNNDANSYYEESNIYDNETSEEENSSNICELKSYKKLGNLIKTCVVDITADDTPTNICELETVDIILLIFVLSSVQPDKMKNVINNSYKYLKKGGYVLLRDYGLYDLAQVRFANKREKKISENFYVRGDKTFVYFFRIEELRDLFCQNSLFEEIENKYITRIVKNRKRNIEMKRIWVQSIFKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX32</accession>
    <name>A0A1J1GX32_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Replication termination factor, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00439700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529619.1">
        <property type="nucleotide sequence ID" value="XM_028673136.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX32"/>
    <dbReference type="GeneID" id="39732930"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00439700"/>
    <dbReference type="OMA" id="EFRWLHC"/>
    <dbReference type="OrthoDB" id="247013at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006274">
        <property type="term" value="P:DNA replication termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006735">
        <property type="entry name" value="Rtf2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12775">
        <property type="entry name" value="PROTEIN C20ORF43 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12775:SF0">
        <property type="entry name" value="REPLICATION TERMINATION FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04641">
        <property type="entry name" value="Rtf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="227" mass="26482" checksum="5830FFFAA21E2389" modified="2017-02-15" version="1">MGGDGGSLPQRVDLVKMKNKKLKENTGSLGYEKNTLVTINHNKYNKKELKEYYFNHCAISQEPIFCCRLGYLYNKENILKLILFRKQNKKKRKKDIYEKFSHIDSLKDVISCKNKLNEESKLICLISNEIINSTSGGICIFSCGCTFSKKVFNHVNNTKENLCMTCNKKYKLSDIIEIGIDDESILEEKKKIIKKRKLNKNKELSRENKEISNERKEKKKKIDNIIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX48</accession>
    <name>A0A1J1GX48_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sulfhydryl oxidase</fullName>
            <ecNumber evidence="7">1.8.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00462700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2 R'C(R)SH + O2 = R'C(R)S-S(R)CR' + H2O2</text>
            <dbReference type="Rhea" id="RHEA:17357"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:16520"/>
            <dbReference type="ChEBI" id="CHEBI:17412"/>
            <dbReference type="EC" id="1.8.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.3.2" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529850.1">
        <property type="nucleotide sequence ID" value="XM_028673393.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX48"/>
    <dbReference type="GeneID" id="39733160"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00462700"/>
    <dbReference type="OMA" id="YYGFCNI"/>
    <dbReference type="OrthoDB" id="59470at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016971">
        <property type="term" value="F:flavin-dependent sulfhydryl oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.310">
        <property type="entry name" value="ERV/ALR sulfhydryl oxidase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036774">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017905">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039798">
        <property type="entry name" value="Sulfhydryl_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22897">
        <property type="entry name" value="QUIESCIN Q6-RELATED SULFHYDRYL OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22897:SF8">
        <property type="entry name" value="SULFHYDRYL OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04777">
        <property type="entry name" value="Evr1_Alr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69000">
        <property type="entry name" value="FAD-dependent thiol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51324">
        <property type="entry name" value="ERV_ALR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 7" id="KW-0274">FAD</keyword>
    <keyword evidence="2 7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="domain" description="ERV/ALR sulfhydryl oxidase" evidence="8">
        <location>
            <begin position="318"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU371123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG97047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="491" mass="58457" checksum="83BE0E5655A5A59D" modified="2017-02-15" version="1">MIYKYKLKSLYFIFIVIIITLLMKCDELCQDADIILNNFWDKINNIKHGNVLIINIKNFYCPACNRYLNIWKKVENEILNFEKNASLFVFDCSCHLFSSYCRHFDVEYYPTFRLLFPVYDKMEGNEYIYIAPSDYIGNKTYKGNLLLAYREIQRIKGIDGFQKLMHKYLCNNVNFNHINLKSCISDLPHINKRTLDNIIVEGIINESNSLYEDEKANKWNISYNKEDIKHDIIIGLLYTLKQNISMGNDINYSSLESYIDILNIVSYIYKDLANSINEISETLRTYKYPIRYEEWIKLIQNININEYHLDEKNNLHFKVCNENSLLCTFWLLFHKISIYCLQYDKERYNFYLEKITNYTKNYLNCKNCTEHFLNAQKSCYYGFCNIHSAESFVIFLWRIHNGVTLRSMYEHIILDLELGTDNSNNKKFLNKDIVFPSKYQCENCRSGVGFTKITADVIKKLEKGTYNDQHFDAIDAFNIRNILIFLINFYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXE6</accession>
    <name>A0A1J1GXE6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00481200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530036.1">
        <property type="nucleotide sequence ID" value="XM_028673600.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXE6"/>
    <dbReference type="GeneID" id="39733345"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00481200"/>
    <dbReference type="OMA" id="WSYAFIY"/>
    <dbReference type="OrthoDB" id="410044at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000445">
        <property type="entry name" value="RNA-binding protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050502">
        <property type="entry name" value="Euk_RNA-bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48025">
        <property type="entry name" value="OS02G0815200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48025:SF1">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="299"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="403"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="554"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1189"/>
            <end position="1212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="554"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1240" mass="146277" checksum="94DB0D8EC20329A9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXL5</accession>
    <name>A0A1J1GXL5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">LEM3/CDC50 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00488700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CDC50/LEM3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530110.1">
        <property type="nucleotide sequence ID" value="XM_028673682.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXL5"/>
    <dbReference type="GeneID" id="39733420"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00488700"/>
    <dbReference type="OMA" id="FYVTHKK"/>
    <dbReference type="OrthoDB" id="340608at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005045">
        <property type="entry name" value="CDC50/LEM3_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10926:SF0">
        <property type="entry name" value="CDC50, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10926">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03381">
        <property type="entry name" value="CDC50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="400"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="493" mass="58243" checksum="71AE34B20BE5C0E6" modified="2017-02-15" version="1">MTEDSLHEKDFSLISVNYDACEEIFKSFKRRNHIGVPIHGKVMNEECTTENNKEKNKKKKIISFEGEISNVMIIKDEMDEKLNKTDHININVPEQKRSDTLLRKKNYIFNESKYNEFMDLLKQQHLKKFNKFHYVYKWKIALIILLILSFVFLLIGFYIYYESSNVTEVNIDYELDDEFKLFRIKKDMKKPVYIYYKISNFYVNYKTFLSDESHSLLKESRCKYIKTLEDLYNYRCVNNIQTLPEINSYVDKSGKKENKKCDISSISIEEKNKRIFPCGLVAASIFNDKIDLSFKSESFHIDKFSILNHFDFLVYIKKHKDFSNYNIWINGFSPEYKNWTRSPMTSSFIKPYGVINQDLKAGHNYKIAFTQNTWPSKEWNAKKSFQLISLGVIGNSTFELAYSFFLISLIYIIIIIIMLILVKCNYCKLGKTFSYCKMSKNKNSNVIIFQKKSNVKSESGDIKQLEELNKKDSVNNIIIASNNIQKFCFCPLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXV5</accession>
    <name>A0A1J1GXV5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00376700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000097">
        <property type="protein sequence ID" value="CRG97394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530196.1">
        <property type="nucleotide sequence ID" value="XM_028673778.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732297"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00376700"/>
    <dbReference type="OrthoDB" id="348930at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="288"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="339"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="454"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="663"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1762"/>
            <end position="1789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="339"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="389"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="415"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="454"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="490"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="526"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="540"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="566"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="663"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="678"/>
            <end position="691"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1931" mass="226934" checksum="F3ECB6F796590460" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXZ4</accession>
    <name>A0A1J1GXZ4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00491200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530135.1">
        <property type="nucleotide sequence ID" value="XM_028673709.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXZ4"/>
    <dbReference type="GeneID" id="39733445"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00491200"/>
    <dbReference type="OMA" id="EKNKSFC"/>
    <dbReference type="OrthoDB" id="341575at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="419" mass="50106" checksum="8FB4B0D5CE4423AC" modified="2017-02-15" version="1">MSDNDLEIIPNIYERFEEKNKEVVKDSESDNDSKDEKSENNDITVNKDSKFYKKLYSFIESKSKYINLILSCKSEMGAKIVYKKKYMKVQNKAFTEIKVENSLNILKEIVKNKFSKYSDEKIDLYLKEIINNPPKENCSLHKKFFKKNEKNIYIKHNIISYILNFMDCKTLMKFKECSKIDNEIVSLYLRKILYTLPFKDEEIKTNIQYWRNVVNYFFYKCGTLIPIDRSNYPIILNALEQNKSFCVITKNSMNSNIFISLDYLNEKLISSCNHNNPLPHTCDTKNEICGVKNLKTEEISMIDFIEEYYKRLRINDDELIWNLCSFRKSSDFLTLLLLEYLKCMSNVVKKYNGKCTFKKTEYFVNCGHHITHRIWIQVFYEYGYESIDFKKKKKNENIDEDNENRTLYLTIADHYKWDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY32</accession>
    <name>A0A1J1GY32_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00504700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530275.1">
        <property type="nucleotide sequence ID" value="XM_028673864.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733580"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00504700"/>
    <dbReference type="OrthoDB" id="377269at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="297"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1298" mass="157789" checksum="2874D6F822EAB19B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY52</accession>
    <name>A0A1J1GY52_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Small subunit rRNA processing factor, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00314900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ESF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528744.1">
        <property type="nucleotide sequence ID" value="XM_028672163.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY52"/>
    <dbReference type="GeneID" id="39731682"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00314900"/>
    <dbReference type="OMA" id="QFHYSVS"/>
    <dbReference type="OrthoDB" id="431825at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039754">
        <property type="entry name" value="Esf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012580">
        <property type="entry name" value="NUC153"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056750">
        <property type="entry name" value="RRM_ESF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12202">
        <property type="entry name" value="ESF1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12202:SF0">
        <property type="entry name" value="ESF1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08159">
        <property type="entry name" value="NUC153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25121">
        <property type="entry name" value="RRM_ESF1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ESF1 RRM" evidence="8">
        <location>
            <begin position="363"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="ESF1 RRM" evidence="8">
        <location>
            <begin position="491"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="domain" description="NUC153" evidence="7">
        <location>
            <begin position="866"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="299"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF25121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG95936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="901" mass="108781" checksum="D5DC4073C17D2A86" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY61</accession>
    <name>A0A1J1GY61_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF155 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00477900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RMD1/sif2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530003.1">
        <property type="nucleotide sequence ID" value="XM_028673563.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY61"/>
    <dbReference type="GeneID" id="39733312"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00477900"/>
    <dbReference type="OrthoDB" id="18302at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003734">
        <property type="entry name" value="DUF155"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051624">
        <property type="entry name" value="RMD1/Sad1-interacting"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16255">
        <property type="entry name" value="REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16255:SF1">
        <property type="entry name" value="REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02582">
        <property type="entry name" value="DUF155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="527"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="domain" description="DUF155" evidence="4">
        <location>
            <begin position="289"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="345"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="352"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="550" mass="66241" checksum="EE197F3911598830" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYE2</accession>
    <name>A0A1J1GYE2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA endonuclease activator Ctp1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00490600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530129.1">
        <property type="nucleotide sequence ID" value="XM_028673703.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYE2"/>
    <dbReference type="GeneID" id="39733439"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00490600"/>
    <dbReference type="OMA" id="NKDKHCN"/>
    <dbReference type="OrthoDB" id="378458at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013882">
        <property type="entry name" value="Ctp1_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08573">
        <property type="entry name" value="SAE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA endonuclease activator Ctp1 C-terminal" evidence="5">
        <location>
            <begin position="495"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="531"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="582" mass="70154" checksum="8624042967B1C500" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYJ1</accession>
    <name>A0A1J1GYJ1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="13">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">PGAL8A_00496200</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. RAD25/XPB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="13"/>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530185.1">
        <property type="nucleotide sequence ID" value="XM_028673765.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYJ1"/>
    <dbReference type="GeneID" id="39733495"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00496200"/>
    <dbReference type="OMA" id="RCQEIDY"/>
    <dbReference type="OrthoDB" id="10262986at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000112">
        <property type="term" value="C:nucleotide-excision repair factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097550">
        <property type="term" value="C:transcription preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18029">
        <property type="entry name" value="DEXHc_XPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18789">
        <property type="entry name" value="SF2_C_XPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000077">
        <property type="entry name" value="Probable DNA repair helicase RAD25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050615">
        <property type="entry name" value="ATP-dep_DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032438">
        <property type="entry name" value="ERCC3_RAD25_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001161">
        <property type="entry name" value="XPB/Ssl2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032830">
        <property type="entry name" value="XPB/Ssl2_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00603">
        <property type="entry name" value="rad25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11274:SF0">
        <property type="entry name" value="GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11274">
        <property type="entry name" value="RAD25/XP-B DNA REPAIR HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16203">
        <property type="entry name" value="ERCC3_RAD25_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13625">
        <property type="entry name" value="Helicase_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00851">
        <property type="entry name" value="XRODRMPGMNTB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 17" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="15">
        <location>
            <begin position="394"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="16">
        <location>
            <begin position="612"/>
            <end position="769"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="CRG97383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="880" mass="102309" checksum="25CBBEEAEA53732A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYJ2</accession>
    <name>A0A1J1GYJ2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA-binding protein s1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00358400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529165.1">
        <property type="nucleotide sequence ID" value="XM_028672631.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYJ2"/>
    <dbReference type="GeneID" id="39732114"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00358400"/>
    <dbReference type="OrthoDB" id="252020at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061574">
        <property type="term" value="C:ASAP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15481:SF0">
        <property type="entry name" value="LD23870P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15481">
        <property type="entry name" value="RIBONUCLEIC ACID BINDING PROTEIN S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="4"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="88"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="88"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="113"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="129"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="139" mass="16207" checksum="AB5786716E5707C8" modified="2017-02-15" version="1">MNNNCIYIYNLTKNVSVDHLKEIFMHFGNLRDINFILDNENVNNNNFMCAKIKFENGVDAKIAKEFMNGGQIDGKIVSIKYEHGINDKEKEKSKTKQRNEKKSYMKDCTSSYSLSRKSNISNNKSKSLSIKRRKKNKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYL8</accession>
    <name>A0A1J1GYL8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Importin subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00523600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the importin alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530461.1">
        <property type="nucleotide sequence ID" value="XM_028674071.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYL8"/>
    <dbReference type="GeneID" id="39733769"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00523600"/>
    <dbReference type="OMA" id="MVRNATW"/>
    <dbReference type="OrthoDB" id="29145at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061608">
        <property type="term" value="F:nuclear import signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000021">
        <property type="entry name" value="Importin subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032413">
        <property type="entry name" value="Arm_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002652">
        <property type="entry name" value="Importin-a_IBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024931">
        <property type="entry name" value="Importin_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23316">
        <property type="entry name" value="IMPORTIN ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00514">
        <property type="entry name" value="Arm"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16186">
        <property type="entry name" value="Arm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01749">
        <property type="entry name" value="IBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005673">
        <property type="entry name" value="Importin_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51214">
        <property type="entry name" value="IBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="IBB" evidence="8">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="6">
        <location>
            <begin position="133"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="6">
        <location>
            <begin position="176"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="6">
        <location>
            <begin position="218"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="6">
        <location>
            <begin position="260"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR005673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG97660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="544" mass="60952" checksum="3625263A35291910" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYU8</accession>
    <name>A0A1J1GYU8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Signal recognition particle SRP19, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00530900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530533.1">
        <property type="nucleotide sequence ID" value="XM_028674151.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYU8"/>
    <dbReference type="GeneID" id="39733842"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00530900"/>
    <dbReference type="OMA" id="QCVVEKN"/>
    <dbReference type="OrthoDB" id="2190947at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006617">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.56.30">
        <property type="entry name" value="Signal recognition particle, SRP19-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002778">
        <property type="entry name" value="Signal_recog_particle_SRP19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036521">
        <property type="entry name" value="SRP19-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17453">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 19 KD PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17453:SF0">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 19 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01922">
        <property type="entry name" value="SRP19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69695">
        <property type="entry name" value="SRP19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0733">Signal recognition particle</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="136" mass="16204" checksum="70C537B711AFE534" modified="2017-02-15" version="1">MIKPEENVNNESLETKDVSRWKIIYPNYINKKKKVKEGRRINLSYCVDDPSIEEIELACKELNVSYYVEKKKCYPRDWQVEGRIRVKLPNIEEQILNKFDLMKKIGIKLQTIKVNNESNTSTNQNNLTKKKKKNQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ64</accession>
    <name>A0A1J1GZ64_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Copper-transporting ATPase, putative</fullName>
            <ecNumber evidence="12">3.6.3.54</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">CuTP</name>
        <name evidence="12" type="ORF">PGAL8A_00417400</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.54" evidence="12"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529397.1">
        <property type="nucleotide sequence ID" value="XM_028672890.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732705"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00417400"/>
    <dbReference type="OrthoDB" id="432719at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043682">
        <property type="term" value="F:P-type divalent copper transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055070">
        <property type="term" value="P:copper ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43520">
        <property type="entry name" value="ATP7, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43520:SF8">
        <property type="entry name" value="P-TYPE CU(+) TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="489"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="766"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="806"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1120"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1163"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1811"/>
            <end position="1834"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1840"/>
            <end position="1865"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="11">
        <location>
            <begin position="1015"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="906"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="1396"/>
            <end position="1423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="908"/>
            <end position="931"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG96593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1868" mass="218497" checksum="07F4CAD837444972" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZL7</accession>
    <name>A0A1J1GZL7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">OTU domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00369200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529272.1">
        <property type="nucleotide sequence ID" value="XM_028672750.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZL7"/>
    <dbReference type="GeneID" id="39732222"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00369200"/>
    <dbReference type="OMA" id="ELFICFH"/>
    <dbReference type="OrthoDB" id="415023at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22748">
        <property type="entry name" value="OTU_OTUD6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.80">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050704">
        <property type="entry name" value="Peptidase_C85-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12419:SF10">
        <property type="entry name" value="DEUBIQUITINASE OTUD6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12419">
        <property type="entry name" value="OTU DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02338">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OTU" evidence="2">
        <location>
            <begin position="135"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="9"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="318" mass="38004" checksum="55693BCE34E4D60B" modified="2017-02-15" version="1">MEDENHISYHEYKRRLKKITEEIKKEKKKTCNKIKKSENLLKLEEELNKLNSLYNDHNNEGKNNNINENKNECENINNLVTDNLYLYNEISKKALKNRKKAKQKELEEIRNEKLKNKCGEKEYEELLENLKKLNKTIFPIPPDGNCLYESILHQLRERNKNYKYTLTDFLNIINKENFSLNNVDLNDYRNKNNFDFSIFPNINPYDLSSDILRFLTSIYLLQNKSLFINFIYVNQNNMNSDSDDDPFFNYCKEIINGIYGSEIEIKALSNILQKKITVYDVNMNVSYEENYDKELHICFHHKLYALGKHYNSVIDLET</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZS6</accession>
    <name>A0A1J1GZS6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ER membrane protein complex subunit 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">EMC6</name>
        <name evidence="9" type="ORF">PGAL8A_00529000</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EMC6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530514.1">
        <property type="nucleotide sequence ID" value="XM_028674130.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZS6"/>
    <dbReference type="GeneID" id="39733823"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00529000"/>
    <dbReference type="OMA" id="MKANFEW"/>
    <dbReference type="OrthoDB" id="16510at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072546">
        <property type="term" value="C:EMC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008504">
        <property type="entry name" value="Emc6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029008">
        <property type="entry name" value="EMC6-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20994">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20994:SF0">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07019">
        <property type="entry name" value="EMC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG97713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="124" mass="14578" checksum="8FE2583ED285E24D" modified="2017-02-15" version="1">MEKKINNKEDEVNLMNNLDLKFLEDKKYDEHKIKHNQHSLILSKQFYGIISGITVGILGIQGIYGFLFFILFTLIGTLMTYFHIKNNFNSFFLKKSEVLCGDIFSGLISFILFWTLTYDILYIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZT7</accession>
    <name>A0A1J1GZT7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein Mpv17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00023400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530600.1">
        <property type="nucleotide sequence ID" value="XM_028674226.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZT7"/>
    <dbReference type="GeneID" id="39728757"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00023400"/>
    <dbReference type="OMA" id="IACQMME"/>
    <dbReference type="OrthoDB" id="10267969at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF80">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="256"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="292"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="331"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="373"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="400"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="421" mass="50191" checksum="779552FA74AB5C5F" modified="2017-02-15" version="1">MKFGTYYMDIKRKHLNFASKNVNLSFLENNIKRWYFTERYIHSKFLNNENVKIKKLYLFNTYMNLKELKISEIDENKFHYLHRKPDYTIDNYSKVDELNKRKKLKEKKSNLFNNQTANPNSLAHIENLNNIINIKINNIFYKTKIYKNFYTMNNQKHIQCKTGNIKEKENIENIQNISNQIKEEKNIKDTNIDNNTNSILNNEEKKIIKTHMQIKDVNDVIIDIKNEKNVVIEKKKYSFYISKIALLLNNLFEKHLLLMNCLIAGTLYMIADIACQIMEVHNKNKDYDFLRTLRMSFIGLSLEGPIMTWWYGKILSNFIKSKPNTFIYKSLFPTLFDNFIFGPIHLAVFFFYNGILKNQKKSEIVDKIVNTGIKVFLVSLMTWTPLTLVNFIFVPRIYQATVVFFADFFWVIFLSWCANKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H003</accession>
    <name>A0A1J1H003_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00050000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530862.1">
        <property type="nucleotide sequence ID" value="XM_028674517.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H003"/>
    <dbReference type="GeneID" id="39729025"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00050000"/>
    <dbReference type="OMA" id="IMKPEMK"/>
    <dbReference type="OrthoDB" id="374082at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034551">
        <property type="term" value="P:mitochondrial respiratory chain complex III assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027858">
        <property type="entry name" value="BRAWNIN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14990">
        <property type="entry name" value="DUF4516"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="64" mass="7372" checksum="03FCBCA34084A913" modified="2017-02-15" version="1">MPLGVPLKKYLFIVSTSFLCMAMGSCCVHLIMKPEMKEYDISKHLENRNNAIQEVQKDIIKNKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0T4</accession>
    <name>A0A1J1H0T4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cg7 protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00049600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530858.1">
        <property type="nucleotide sequence ID" value="XM_028674513.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0T4"/>
    <dbReference type="GeneID" id="39729021"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00049600"/>
    <dbReference type="OMA" id="FQATIMS"/>
    <dbReference type="OrthoDB" id="371707at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="917"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="630"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="725"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="932"/>
            <end position="949"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1004" mass="120659" checksum="96066CBA6DB48EBB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H261</accession>
    <name>A0A1J1H261_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Deoxyhypusine hydroxylase</fullName>
            <shortName evidence="9">DOHH</shortName>
            <ecNumber evidence="9">1.14.99.29</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Deoxyhypusine dioxygenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Deoxyhypusine monooxygenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">DOHH</name>
        <name evidence="10" type="ORF">PGAL8A_00498600</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>[eIF5A protein]-deoxyhypusine + AH2 + O2 = [eIF5A protein]-hypusine + A + H2O</text>
            <dbReference type="Rhea" id="RHEA:14101"/>
            <dbReference type="Rhea" id="RHEA-COMP:10144"/>
            <dbReference type="Rhea" id="RHEA-COMP:12592"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:82657"/>
            <dbReference type="ChEBI" id="CHEBI:91175"/>
            <dbReference type="EC" id="1.14.99.29"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="9">Binds 2 Fe(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Protein modification; eIF5A hypusination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the deoxyhypusine hydroxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.99.29" evidence="9"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530215.1">
        <property type="nucleotide sequence ID" value="XM_028673798.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H261"/>
    <dbReference type="GeneID" id="39733519"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00498600"/>
    <dbReference type="OMA" id="HGDGPRC"/>
    <dbReference type="OrthoDB" id="421002at2759"/>
    <dbReference type="UniPathway" id="UPA00354"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019135">
        <property type="term" value="F:deoxyhypusine monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03101">
        <property type="entry name" value="Deoxyhypusine_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027517">
        <property type="entry name" value="Deoxyhypusine_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004155">
        <property type="entry name" value="PBS_lyase_HEAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12697:SF5">
        <property type="entry name" value="DEOXYHYPUSINE HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12697">
        <property type="entry name" value="PBS LYASE HEAT-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13646">
        <property type="entry name" value="HEAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00567">
        <property type="entry name" value="EZ_HEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0386">Hypusine biosynthesis</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG97414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="342" mass="39097" checksum="BDAFB52D65892593" modified="2017-02-15" version="1">MSNNNSIKRLIKYEESNNKDFIEKYLVKTKNEFIEKQMRALYECREVHKGNIDEIINILSFALENNDSVLLRHEIAYVLGQISNEKCNNILIKLLNDKNENVMVRHEAAEGLAAIGSESNILIIKKFLNDESIEVRETCELALSSLLEKNKNPFCSCINKENIKELLRKKQSDEFVSKKFKTIDPVVFISKNKSVDKLIEDLNNEDNPLKLRYEALFQLRDMESDISLNALGEALIKDNKSAIFRHEVAFVLGQALHLNSLKYLISSLTNINEHEMVRHEVALALGSLGSLNLNSEEYKNIQNTIINTLKMYSKDKCKVVAESCLVGLDYIAENLNIAIEIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2Q1</accession>
    <name>A0A1J1H2Q1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Zinc transporter, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00520600</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530431.1">
        <property type="nucleotide sequence ID" value="XM_028674038.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2Q1"/>
    <dbReference type="GeneID" id="39733739"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00520600"/>
    <dbReference type="OMA" id="NISNCET"/>
    <dbReference type="OrthoDB" id="9944568at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050681">
        <property type="entry name" value="CDF/SLC30A"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11562">
        <property type="entry name" value="CATION EFFLUX PROTEIN/ ZINC TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11562:SF17">
        <property type="entry name" value="RE54080P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="Cation efflux protein cytoplasmic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0864">Zinc transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="33"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="11">
        <location>
            <begin position="33"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="11">
        <location>
            <begin position="349"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein cytoplasmic" evidence="12">
        <location>
            <begin position="429"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="241"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="241"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG97630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="519" mass="59111" checksum="89F867CF51288C13" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3M3</accession>
    <name>A0A1J1H3M3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Translation initiation factor IF-2, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">MB2</name>
        <name evidence="11" type="ORF">PGAL8A_00038100</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530743.1">
        <property type="nucleotide sequence ID" value="XM_028674384.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728905"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00038100"/>
    <dbReference type="OMA" id="VQDMDVQ"/>
    <dbReference type="OrthoDB" id="361630at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01887">
        <property type="entry name" value="IF2_eIF5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03702">
        <property type="entry name" value="IF2_mtIF2_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03692">
        <property type="entry name" value="mtIF2_IVc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000008">
        <property type="entry name" value="Translation initiation factor IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000054">
        <property type="entry name" value="Translation initiation factor IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10050:FF:000001">
        <property type="entry name" value="Translation initiation factor IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000019">
        <property type="entry name" value="Translation initiation factor IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10050">
        <property type="entry name" value="Translation initiation factor IF- 2, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053905">
        <property type="entry name" value="EF-G-like_DII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044145">
        <property type="entry name" value="IF2_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015760">
        <property type="entry name" value="TIF_IF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023115">
        <property type="entry name" value="TIF_IF2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036925">
        <property type="entry name" value="TIF_IF2_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381:SF5">
        <property type="entry name" value="TR-TYPE G DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22042">
        <property type="entry name" value="EF-G_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11987">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52156">
        <property type="entry name" value="Initiation factor IF2/eIF5b, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="10">
        <location>
            <begin position="961"/>
            <end position="1130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="885"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="164"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="305"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="277"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG97944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1545" mass="179936" checksum="5856A8D98FD02AD2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3P1</accession>
    <name>A0A1J1H3P1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00053800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530900.1">
        <property type="nucleotide sequence ID" value="XM_028674560.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3P1"/>
    <dbReference type="GeneID" id="39729063"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00053800"/>
    <dbReference type="OMA" id="ICNIQAY"/>
    <dbReference type="OrthoDB" id="370877at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012181809" evidence="1">
        <location>
            <begin position="20"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="145" mass="17656" checksum="79C8312E17A4A75E" modified="2017-02-15" version="1">MELKFIFIFFLFFIHNLKAFILNKKFRNLCTKYSSNKNRVKLSLKINDIINFKNKKDLKKDIIKHSKKLCLDLNDEQIKIIENNLYEFFYYLKLKNINIDVKKRKSKYSKLLPLCVKEKRQKKFHTTNLKKENDYFIVNSNSFSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3Q3</accession>
    <name>A0A1J1H3Q3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00000300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000131">
        <property type="protein sequence ID" value="CRG97976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530775.1">
        <property type="nucleotide sequence ID" value="XM_028674419.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3Q3"/>
    <dbReference type="GeneID" id="39728525"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00000300"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="110" mass="13146" checksum="6318F5CCD96ECE30" modified="2017-02-15" version="1">MSLKYASRTFRLDDNSDLYLVSRPDGSTYYYNAEYMKSYYLDKNEILIIGIFSAIWFFCIIFGIYVFINERARRQRILNNLMLEVMSIDSGYWEDNNEELEQEAVDISNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3Q4</accession>
    <name>A0A1J1H3Q4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Dipeptidyl peptidase 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Cathepsin C</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Cathepsin J</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Dipeptidyl peptidase I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Dipeptidyl transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">DPAP3</name>
        <name evidence="16" type="ORF">PGAL8A_00055400</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Thiol protease. Has dipeptidylpeptidase activity. Active against a broad range of dipeptide substrates composed of both polar and hydrophobic amino acids. Proline cannot occupy the P1 position and arginine cannot occupy the P2 position of the substrate. Can act as both an exopeptidase and endopeptidase. Activates serine proteases such as elastase, cathepsin G and granzymes A and B.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>chloride</name>
            <dbReference type="ChEBI" id="CHEBI:17996"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Tetramer of heterotrimers consisting of exclusion domain, heavy- and light chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase C1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530916.1">
        <property type="nucleotide sequence ID" value="XM_028674578.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3Q4"/>
    <dbReference type="GeneID" id="39729079"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00055400"/>
    <dbReference type="OMA" id="DFFNQGC"/>
    <dbReference type="OrthoDB" id="3789175at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.80">
        <property type="entry name" value="Cathepsin C, exclusion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014882">
        <property type="entry name" value="CathepsinC_exc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036496">
        <property type="entry name" value="CathepsinC_exc_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000169">
        <property type="entry name" value="Pept_cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025660">
        <property type="entry name" value="Pept_his_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013128">
        <property type="entry name" value="Peptidase_C1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000668">
        <property type="entry name" value="Peptidase_C1A_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12411">
        <property type="entry name" value="CYSTEINE PROTEASE FAMILY C1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08773">
        <property type="entry name" value="CathepsinC_exc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00112">
        <property type="entry name" value="Peptidase_C1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00645">
        <property type="entry name" value="Pept_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75001">
        <property type="entry name" value="Dipeptidyl peptidase I (cathepsin C), exclusion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00139">
        <property type="entry name" value="THIOL_PROTEASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00639">
        <property type="entry name" value="THIOL_PROTEASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013153651" description="Dipeptidyl peptidase 1" evidence="14">
        <location>
            <begin position="18"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C1A papain C-terminal" evidence="15">
        <location>
            <begin position="397"/>
            <end position="821"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="CRG98119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="842" mass="101836" checksum="18C2AB6F474398E5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3S7</accession>
    <name>A0A1J1H3S7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00043300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530799.1">
        <property type="nucleotide sequence ID" value="XM_028674448.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728958"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00043300"/>
    <dbReference type="OMA" id="FPCFFSE"/>
    <dbReference type="OrthoDB" id="196858at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048188">
        <property type="term" value="C:Set1C/COMPASS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037850">
        <property type="entry name" value="RBBP5/Swd1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44040">
        <property type="entry name" value="RETINOBLASTOMA-BINDING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44040:SF1">
        <property type="entry name" value="RETINOBLASTOMA-BINDING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="655"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="787"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1241"/>
            <end position="1268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="114"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="655"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="667"/>
            <end position="735"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG98002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1310" mass="157346" checksum="FE11457254222964" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2012-07-11" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>I2FKC0</accession>
    <name>I2FKC0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Triosephosphate isomerase</fullName>
            <ecNumber evidence="10">5.3.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">TPI</name>
        <name evidence="12" type="ORF">PGAL8A_00199100</name>
    </gene>
    <organism evidence="11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2012" name="Gene" volume="502" first="36" last="39">
            <title>Age of the last common ancestor of extant Plasmodium parasite lineages.</title>
            <authorList>
                <person name="Hayakawa T."/>
                <person name="Tachibana S."/>
                <person name="Hikosaka K."/>
                <person name="Arisue N."/>
                <person name="Matsui A."/>
                <person name="Horii T."/>
                <person name="Tanabe K."/>
            </authorList>
            <dbReference type="PubMed" id="22555021"/>
            <dbReference type="DOI" id="10.1016/j.gene.2012.04.037"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="12 13" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the interconversion of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate in the glycolytic and gluconeogenic pathways.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:18585"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="5.3.1.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:18586"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the triosephosphate isomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.1" evidence="10"/>
    <dbReference type="EMBL" id="AB571129">
        <property type="protein sequence ID" value="BAM15605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="I2FKC0"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00199100"/>
    <dbReference type="OMA" id="NWKMHMT"/>
    <dbReference type="OrthoDB" id="6715177at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00189"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004807">
        <property type="term" value="F:triose-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046166">
        <property type="term" value="P:glyceraldehyde-3-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00311">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000016">
        <property type="entry name" value="Triosephosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00147_B">
        <property type="entry name" value="TIM_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035990">
        <property type="entry name" value="TIM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022896">
        <property type="entry name" value="TrioseP_Isoase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000652">
        <property type="entry name" value="Triosephosphate_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020861">
        <property type="entry name" value="Triosephosphate_isomerase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00419">
        <property type="entry name" value="tim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139">
        <property type="entry name" value="TRIOSEPHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139:SF2">
        <property type="entry name" value="TRIOSEPHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00121">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51351">
        <property type="entry name" value="Triosephosphate isomerase (TIM)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00171">
        <property type="entry name" value="TIM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51440">
        <property type="entry name" value="TIM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="6 10" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 10 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00052432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00056661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAM15605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG94594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="248" mass="28325" checksum="09837E716BFEAB56" modified="2012-07-11" version="1">MSRKYFVAANWKCNGTQKSIKALIENFNKLNFDPNKIDVVIFPVSVHYEYTRKLLDKKFSMGIQNTSKYGNGSYTGEISAEIAKDMNVEYVIIGHFERRKYFFEKDEDVREKLQQCLKNNLKAVVCFGESLEEREQNKTIDVIKTQVKAFIDLIQNFDNVILAYEPLWAIGTGKTATPEQAQNVHKEIRNIVKENCGEKQSKQIRILYGGSVNTENCASLIKQEDIDGFLVGNASLKDTFVDIIKSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2012-07-11" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>I2FKD7</accession>
    <name>I2FKD7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7 8">Cytochrome c oxidase assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">COX11</name>
        <name evidence="8" type="ORF">PGAL8A_00196000</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2012" name="Gene" volume="502" first="36" last="39">
            <title>Age of the last common ancestor of extant Plasmodium parasite lineages.</title>
            <authorList>
                <person name="Hayakawa T."/>
                <person name="Tachibana S."/>
                <person name="Hikosaka K."/>
                <person name="Arisue N."/>
                <person name="Matsui A."/>
                <person name="Horii T."/>
                <person name="Tanabe K."/>
            </authorList>
            <dbReference type="PubMed" id="22555021"/>
            <dbReference type="DOI" id="10.1016/j.gene.2012.04.037"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="8 9" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
            <orientation evidence="2">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AB571146">
        <property type="protein sequence ID" value="BAM15622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="I2FKD7"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00196000"/>
    <dbReference type="OMA" id="NKLECFC"/>
    <dbReference type="OrthoDB" id="1704689at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.370.10:FF:000001">
        <property type="entry name" value="COX11 cytochrome c oxidase assembly homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.370.10">
        <property type="entry name" value="Ctag/Cox11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00155">
        <property type="entry name" value="CtaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023471">
        <property type="entry name" value="CtaG/Cox11_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007533">
        <property type="entry name" value="Cyt_c_oxidase_assmbl_CtaG"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003465">
        <property type="entry name" value="PRK05089.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21320:SF3">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21320">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04442">
        <property type="entry name" value="CtaG_Cox11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005413">
        <property type="entry name" value="COX11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110111">
        <property type="entry name" value="Ctag/Cox11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAM15622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="227" mass="26625" checksum="B315BF9D6C7ABE0B" modified="2012-07-11" version="1">MSIIKNFFNRFNLRNRNKVNNFMIIEKKERLEIPYVYLSISAFMFGLSFAFVPLYQLFCQSTGYGGTIQKKLDINKILKKKENHKNRLIEINFTSQSNMPWVFEPEQKSIIVKPGETVLAFYKAKNLLDKPIIGIALYHVLPDEAGLYFNKIQCFCFEEQMLNANEEIDLPVLFFIDPDILNDSRLKNLEKITLSYIFFESDSEIPEEYQHLSRAISSKKKPEIQVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKT0</accession>
    <name>A0A1J1GKT0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00068600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG92982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525804.1">
        <property type="nucleotide sequence ID" value="XM_028671976.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKT0"/>
    <dbReference type="GeneID" id="39729211"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00068600"/>
    <dbReference type="OrthoDB" id="273556at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007265">
        <property type="term" value="P:Ras protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001607">
        <property type="entry name" value="Znf_UBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24007">
        <property type="entry name" value="BRCA1-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24007:SF7">
        <property type="entry name" value="BRCA1-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50271">
        <property type="entry name" value="ZF_UBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="720"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="domain" description="UBP-type" evidence="5">
        <location>
            <begin position="735"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="775"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1103"/>
            <end position="1130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG92982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1230" mass="148168" checksum="C6471E3CEAD02182" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKX2</accession>
    <name>A0A1J1GKX2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">40S ribosomal protein S24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RPS24</name>
        <name evidence="7" type="ORF">PGAL8A_00066800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG92964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525786.1">
        <property type="nucleotide sequence ID" value="XM_028669977.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKX2"/>
    <dbReference type="GeneID" id="39729193"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00066800"/>
    <dbReference type="OMA" id="RKPRERC"/>
    <dbReference type="OrthoDB" id="10251131at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.3370:FF:000001">
        <property type="entry name" value="40S ribosomal protein S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00545">
        <property type="entry name" value="Ribosomal_eS24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053709">
        <property type="entry name" value="eRP_eS24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001976">
        <property type="entry name" value="Ribosomal_eS24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018098">
        <property type="entry name" value="Ribosomal_eS24_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_uL23/eL15/eS24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10496">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01282">
        <property type="entry name" value="Ribosomal_S24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="Ribosomal proteins S24e, L23 and L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00529">
        <property type="entry name" value="RIBOSOMAL_S24E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="104"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG92964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="133" mass="15349" checksum="B7DCA0B31EFD95EB" modified="2017-02-15" version="1">MADQFTIRIKKFMQNPLLCRKQFALEILHPNRGSVSKKEVKEKLAKMYKLNDVGTIILFGFKTLFGGGRTKGFGLIYKNVEAVKKFEKKYRLIREGLITKETKTGRRAAKELKNRRKKVRGTEKTKVSGAKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL85</accession>
    <name>A0A1J1GL85_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">26S proteasome AAA-ATPase subunit RPT3, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00087000</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525988.1">
        <property type="nucleotide sequence ID" value="XM_028671222.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL85"/>
    <dbReference type="GeneID" id="39729394"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00087000"/>
    <dbReference type="OMA" id="FIVMRIS"/>
    <dbReference type="OrthoDB" id="10255768at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000033">
        <property type="entry name" value="26S protease regulatory subunit 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000078">
        <property type="entry name" value="26S protease regulatory subunit 6B homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000293">
        <property type="entry name" value="26S protease regulatory subunit 6B homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032501">
        <property type="entry name" value="Prot_ATP_ID_OB_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16450">
        <property type="entry name" value="Prot_ATP_ID_OB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 10" id="KW-0647">Proteasome</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="9">
        <location>
            <begin position="171"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="10"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG93166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="392" mass="44679" checksum="2E4D663E1B7BD52D" modified="2017-02-15" version="1">MESFNKNTVEEDYYLKLKNLKKQIDILNIQEEYIKEEHKNLKRELIRSKNEIKRIQSVPLIIGQFLDIIDNNYGIVSSTAGSNYYVRILSTLNKEDLKPSVSVALHRHSHSIVNILPSESDSSIQLLQVTEKPNVKYTDLGGLDTQKQEMKEAVELPLTCPELYEKIGIEPPMGILIYGPPGTGKTMLVKAVANETKVTFIGVVGSEFVQKYLGEGPRMVRDVFRLARENSPSIIFIDEVDAIATKRFDAQTGADREVQRILLELLNQMDGFDKSTNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRKQKRLIFQTIISKMNVSSDVNIENFVVRTDKISAADIAAIAQEAGMQAIRKNRYIITANDFEQGYRTHVRKQLRDYEFYNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLN3</accession>
    <name>A0A1J1GLN3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Allantoicase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00095800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the allantoicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526074.1">
        <property type="nucleotide sequence ID" value="XM_028672176.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729482"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00095800"/>
    <dbReference type="OMA" id="CIVKLCK"/>
    <dbReference type="OrthoDB" id="10266039at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004037">
        <property type="term" value="F:allantoicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000256">
        <property type="term" value="P:allantoin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005164">
        <property type="entry name" value="Allantoicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015908">
        <property type="entry name" value="Allantoicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12045">
        <property type="entry name" value="ALLANTOICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12045:SF3">
        <property type="entry name" value="INACTIVE ALLANTOICASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03561">
        <property type="entry name" value="Allantoicase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Allantoicase" evidence="4">
        <location>
            <begin position="1923"/>
            <end position="1976"/>
        </location>
    </feature>
    <feature type="domain" description="Allantoicase" evidence="4">
        <location>
            <begin position="2221"/>
            <end position="2281"/>
        </location>
    </feature>
    <feature type="domain" description="Allantoicase" evidence="4">
        <location>
            <begin position="2304"/>
            <end position="2478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1113"/>
            <end position="1173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1353"/>
            <end position="1440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="2164"/>
            <end position="2190"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="863"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1134"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1353"/>
            <end position="1375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1376"/>
            <end position="1401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1402"/>
            <end position="1440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="2164"/>
            <end position="2176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="2177"/>
            <end position="2189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2481" mass="295138" checksum="037DA2EA6D0BDC42" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLX5</accession>
    <name>A0A1J1GLX5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">60S ribosomal protein L7ae/L30e, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00093300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526051.1">
        <property type="nucleotide sequence ID" value="XM_028671921.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLX5"/>
    <dbReference type="GeneID" id="39729457"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00093300"/>
    <dbReference type="OMA" id="PIDIICH"/>
    <dbReference type="OrthoDB" id="5364946at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018492">
        <property type="entry name" value="Ribosomal_eL8/Nhp2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00881">
        <property type="entry name" value="L7ARS6FAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="3">
        <location>
            <begin position="94"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="221" mass="25915" checksum="B24C3D06AF8D0E3C" modified="2017-02-15" version="1">METTKTTSEINILTKNEGKNNIVNEENVDNDKKKKNYDKSIEEIKIENKNCYISKISEPLLKKKYYKNFLKILDYAYYAKVSASHIIKTNINLDEERKKILKTKFIVIGLSQVIKAIRKGFQGIVILAVDIFPINIICHLPAFCEESNIPYTFVTTKNKLAHLCKLKRSITCLFIFKPNDEIYKFEETINEYNNKQKIVNYEKLYDKLLKGVKKNHPFFQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM55</accession>
    <name>A0A1J1GM55_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Magnesium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00120900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526324.1">
        <property type="nucleotide sequence ID" value="XM_028674721.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM55"/>
    <dbReference type="GeneID" id="39729734"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00120900"/>
    <dbReference type="OMA" id="YYRICCC"/>
    <dbReference type="OrthoDB" id="165382at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008521">
        <property type="entry name" value="Mg_trans_NIPA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570:SF65">
        <property type="entry name" value="MAGNESIUM TRANSPORTER NIPA9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05653">
        <property type="entry name" value="Mg_trans_NIPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="138"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="615"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="656"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="686"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="717"/>
            <end position="738"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="751" mass="88122" checksum="A172D453AFCA88A4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM95</accession>
    <name>A0A1J1GM95_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Holocytochrome c-type synthase</fullName>
            <ecNumber evidence="10">4.4.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00125700</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>holo-[cytochrome c] = apo-[cytochrome c] + heme b</text>
            <dbReference type="Rhea" id="RHEA:22648"/>
            <dbReference type="Rhea" id="RHEA-COMP:10725"/>
            <dbReference type="Rhea" id="RHEA-COMP:10726"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="ChEBI" id="CHEBI:83739"/>
            <dbReference type="EC" id="4.4.1.17"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the cytochrome c-type heme lyase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.17" evidence="10"/>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526372.1">
        <property type="nucleotide sequence ID" value="XM_028674774.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM95"/>
    <dbReference type="GeneID" id="39729782"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00125700"/>
    <dbReference type="OMA" id="NEESWKH"/>
    <dbReference type="OrthoDB" id="4243at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004408">
        <property type="term" value="F:holocytochrome-c synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000511">
        <property type="entry name" value="Holocyt_c/c1_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12743">
        <property type="entry name" value="CYTOCHROME C1 HEME LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12743:SF8">
        <property type="entry name" value="PROTEIN HRI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01265">
        <property type="entry name" value="Cyto_heme_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00822">
        <property type="entry name" value="CYTO_HEME_LYASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0349">Heme</keyword>
    <keyword evidence="6 10" id="KW-0408">Iron</keyword>
    <keyword evidence="9 10 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 10" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG93550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="228" mass="27494" checksum="3DAEE3A257380C96" modified="2017-02-15" version="1">MLNIGRTNDTNSNDEKVKCPSKVEDSSTFEIVEKINKRNMMPEIPNYSLNKDDNFSLSKKRHISSIPKNNEEYWLYPSSQQFYNSLLRKNKDVEKDYIDAVVSIHNEINEESWKHILKYELMHKKKCSNVTLHRFVGKSDELSIKARFRSIFSRLGKPFDRHDWFIDRCGTQIKYILDYYNDESINDDKNIYIDVRPAMDSLSNIWDRLRYPFYEFYFKHIKKNDLYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMC8</accession>
    <name>A0A1J1GMC8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Splicing factor 3B subunit 6, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SF3B6</name>
        <name evidence="8" type="ORF">PGAL8A_00126000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526375.1">
        <property type="nucleotide sequence ID" value="XM_028674777.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMC8"/>
    <dbReference type="GeneID" id="39729785"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00126000"/>
    <dbReference type="OMA" id="AAKRANX"/>
    <dbReference type="OrthoDB" id="275748at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12241">
        <property type="entry name" value="RRM_SF3B14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000432">
        <property type="entry name" value="Splicing factor 3B subunit 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034150">
        <property type="entry name" value="SF3B6_RRM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="14"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="109" mass="12607" checksum="F9B6C185ABBE0D3D" modified="2017-02-15" version="1">MSRRSIRLPPEVSRILYVRNLPYKISADELYDIFGKYGTVRQIRKGNSEGTKGTSFVVYDDIYDAKNALDHLSGFNVAGRYLVVLYYDPVKAQKKKELQEKLKNEKESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMP1</accession>
    <name>A0A1J1GMP1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fam-h protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00123200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526347.1">
        <property type="nucleotide sequence ID" value="XM_028674747.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMP1"/>
    <dbReference type="GeneID" id="39729757"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00123200"/>
    <dbReference type="OMA" id="ICNSHTE"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022139">
        <property type="entry name" value="Fam-L/Fam-M-like_plasmodium"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12420">
        <property type="entry name" value="DUF3671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="203"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="106"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="228" mass="26932" checksum="D04C37FA85022BFB" modified="2017-02-15" version="1">MRDYIHSNIILNSICNSHTEENFVIEDISSLKKYRTRGKINKLFFFIKIFLFTLLIWILHYCENYSYRSWNDKYNLKNKLDLGSKRSLAEGKEVIEPKKEELKVSSSNIQINLEEHNTKVEKLKLKEEEKDKKEIIKIENENVVEKKRDSNKKVNSLHLMQKYKKILRLFNLVSLVTLPILSMTLSIIALYKNDYDNKYVNGTNVVTSLYLVLNSFLLLDLKSNSNNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMR5</accession>
    <name>A0A1J1GMR5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Cyclin-dependent kinase 2 homolog</fullName>
            <ecNumber evidence="5">2.7.11.22</ecNumber>
            <ecNumber evidence="4">2.7.11.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Cell division control protein 2 homolog</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="18">cdc2-related kinase 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="23" type="primary">CRK5</name>
        <name evidence="23" type="ORF">PGAL8A_00144200</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="15">May form a complex composed of at least the catalytic subunit CRK2 and a cyclin.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="5"/>
    <dbReference type="EC" id="2.7.11.23" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526558.1">
        <property type="nucleotide sequence ID" value="XM_028674981.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMR5"/>
    <dbReference type="GeneID" id="39729966"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00144200"/>
    <dbReference type="OMA" id="NKMCHRD"/>
    <dbReference type="OrthoDB" id="1732493at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008353">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF46">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12 23" id="KW-0418">Kinase</keyword>
    <keyword evidence="14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="9 23" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="22">
        <location>
            <begin position="20"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="575"/>
            <end position="597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00038543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00039612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00041902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00042858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="CRG93736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="622" mass="72661" checksum="C5B433315B7B1FE2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMU5</accession>
    <name>A0A1J1GMU5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CCAAT-box DNA binding protein subunit B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00146400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526580.1">
        <property type="nucleotide sequence ID" value="XM_028675006.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMU5"/>
    <dbReference type="GeneID" id="39729988"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00146400"/>
    <dbReference type="OMA" id="INNEFCK"/>
    <dbReference type="OrthoDB" id="372824at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="494"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="670"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="702"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="748"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="786" mass="91406" checksum="C242F1BBE18993AD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN75</accession>
    <name>A0A1J1GN75_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatase 2A regulatory subunit-related protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00162800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526740.1">
        <property type="nucleotide sequence ID" value="XM_028675183.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN75"/>
    <dbReference type="GeneID" id="39730153"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00162800"/>
    <dbReference type="OMA" id="EDIWLFI"/>
    <dbReference type="OrthoDB" id="5586at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041534">
        <property type="entry name" value="EF-hand_13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14095:SF0">
        <property type="entry name" value="MIP22305P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14095">
        <property type="entry name" value="PHOSPHATASE 2A REGULATORY SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17958">
        <property type="entry name" value="EF-hand_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PP2A regulatory subunit B'' EF-hand" evidence="2">
        <location>
            <begin position="637"/>
            <end position="721"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="963" mass="115943" checksum="DA8D7DA6D16DC9B3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN78</accession>
    <name>A0A1J1GN78_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ran-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00159800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526711.1">
        <property type="nucleotide sequence ID" value="XM_028675151.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN78"/>
    <dbReference type="GeneID" id="39730123"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00159800"/>
    <dbReference type="OMA" id="NKRKGFC"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16074">
        <property type="entry name" value="OCRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.10">
        <property type="entry name" value="Zinc finger, RanBP2-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RanBP2-type" evidence="8">
        <location>
            <begin position="489"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="649"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="150"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="206"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="953"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="17"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="29"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="83"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="218"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="255"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="964"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="974"/>
            <end position="990"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1104" mass="133131" checksum="541829EB4B843E42" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNI9</accession>
    <name>A0A1J1GNI9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00159200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526705.1">
        <property type="nucleotide sequence ID" value="XM_028675144.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNI9"/>
    <dbReference type="GeneID" id="39730117"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00159200"/>
    <dbReference type="OMA" id="RHINKCY"/>
    <dbReference type="OrthoDB" id="5126881at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004477">
        <property type="term" value="F:methenyltetrahydrofolate cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004488">
        <property type="term" value="F:methylenetetrahydrofolate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020630">
        <property type="entry name" value="THF_DH/CycHdrlase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48099:SF5">
        <property type="entry name" value="C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48099">
        <property type="entry name" value="C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00763">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic" evidence="1">
        <location>
            <begin position="7"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="616" mass="73107" checksum="7F7338934028A814" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNZ7</accession>
    <name>A0A1J1GNZ7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Rhoptry protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00172900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526843.1">
        <property type="nucleotide sequence ID" value="XM_028670052.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNZ7"/>
    <dbReference type="GeneID" id="39730256"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00172900"/>
    <dbReference type="OMA" id="CIRPFPT"/>
    <dbReference type="OrthoDB" id="378649at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007511">
        <property type="entry name" value="DUF501"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04417">
        <property type="entry name" value="DUF501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="857" mass="102637" checksum="5BE876A293359E56" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPG6</accession>
    <name>A0A1J1GPG6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Saccharopine dehydrogenase NADP binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00409800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the saccharopine dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527212.1">
        <property type="nucleotide sequence ID" value="XM_028670462.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPG6"/>
    <dbReference type="GeneID" id="39732628"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00409800"/>
    <dbReference type="OMA" id="GPYQLYG"/>
    <dbReference type="OrthoDB" id="10268090at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009247">
        <property type="term" value="P:glycolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051276">
        <property type="entry name" value="Saccharopine_DH-like_oxidrdct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005097">
        <property type="entry name" value="Sacchrp_dh_NADP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12286">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12286:SF5">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03435">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Saccharopine dehydrogenase NADP binding" evidence="2">
        <location>
            <begin position="8"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="415" mass="47896" checksum="B5BBEB2F70D8771D" modified="2017-02-15" version="1">MNEKKYDILLLGSTGYTGKMVLEYLLKNYETKIINDEIKLLCAVRSIDRLSKVLISIKEKNNVKIEKINKMECDINDYESILNCCKISNVVISTIGPYAMYGYNIVKGCIEGNAHYLDICGEHTFILKIYKEFNKQAKDKKLKIIHSASFISAISDLGNFIIQNEFLNLYKKPCPYIRVRMSTEGSDLTTIGKATIKSSLLFKKNVGNSYNKHYLCDNKYEHDISCEKKCQQNNSFFDYEKEFGYCFDTAYSKVEEAYVLWSNYLLNYKYGKDLVVDYKQYDPHLTTIKYIIKKIFSIISNFFRSFILPDYFINKYVDLIYKPKTSDELKKAYWKCILIGESHDENMNEKIALYLSGKNEDPGYLLTSKIISESAIALLQDNLPDNFGVVSISVGLGKVIVDRLKKASINIHVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPQ6</accession>
    <name>A0A1J1GPQ6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00188500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000026">
        <property type="protein sequence ID" value="CRG94490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527308.1">
        <property type="nucleotide sequence ID" value="XM_028670569.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPQ6"/>
    <dbReference type="GeneID" id="39730412"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00188500"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="348" mass="41594" checksum="A15FDA7D82A57360" modified="2017-02-15" version="1">MKTLILYLKITTFLLLIWMYQCFYNCDSYKTLIDKNILQTKNKIIYERVLTEGDIAGEKQTYGEECIGECPLDNEKNKWENPVQCENPCDQWHNVIIPSLWEDFNKETSEMDPKLKEKKWNVEWNQISANKVNDLSSIYHRQDISEEEKKKKIYSVMNELISEYVKFLYEFKKEMRVYKKESESKKEIRDNKTESESNKEMRENKTEFESNKKIRDHKSESESMKKMRDNKTESESMKEMIDNKAKSESEKETINNKTESEYEKEITDNNTKSESEKEMRDNKTESESESEKEMRDNKKESESTKEKGTNEIKNYKKKISKLIIVLIFLRRIEYNGLTENIGGVMHKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPZ4</accession>
    <name>A0A1J1GPZ4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Phosphatidylinositol-4-phosphate 5-kinase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PIP5K</name>
        <name evidence="7" type="ORF">PGAL8A_00106400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526181.1">
        <property type="nucleotide sequence ID" value="XM_028673366.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729590"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00106400"/>
    <dbReference type="OrthoDB" id="2129491at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016308">
        <property type="term" value="F:1-phosphatidylinositol-4-phosphate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00139">
        <property type="entry name" value="PIPKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.810.10">
        <property type="entry name" value="2-Layer Sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027483">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002498">
        <property type="entry name" value="PInositol-4-P-4/5-kinase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023610">
        <property type="entry name" value="PInositol-4/5-P-5/4-kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086:SF8">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23086">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01504">
        <property type="entry name" value="PIP5K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00330">
        <property type="entry name" value="PIPKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56104">
        <property type="entry name" value="SAICAR synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51455">
        <property type="entry name" value="PIPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="68"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="PIPK" evidence="6">
        <location>
            <begin position="1074"/>
            <end position="1442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="119"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="640"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="731"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="817"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="119"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="129"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="731"/>
            <end position="764"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1443" mass="172196" checksum="33524860FD18680B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ48</accession>
    <name>A0A1J1GQ48_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00204100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527460.1">
        <property type="nucleotide sequence ID" value="XM_028670737.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ48"/>
    <dbReference type="GeneID" id="39730568"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00204100"/>
    <dbReference type="OMA" id="KNFCIPL"/>
    <dbReference type="OrthoDB" id="372503at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="159" mass="18901" checksum="5BD6A453565E91A4" modified="2017-02-15" version="1">MIKKINIFPLIGKFYNNKCKVSFTSLQLLNKNFDTNNILSFKTTLHVNEGNMKNMLSDKNFCIPLTNCIIYDKKDIYSEIKSKNIIKRNSTENMKLNTPCNLVNKENSRILSFSWLKNVRKKQYYNIIGKIGIKKRNAGMYWSFYVNKRKKIRKKRRTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ67</accession>
    <name>A0A1J1GQ67_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Early transcribed membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ETRAMP</name>
        <name evidence="4" type="ORF">PGAL8A_00180300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527235.1">
        <property type="nucleotide sequence ID" value="XM_028670487.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ67"/>
    <dbReference type="GeneID" id="39730330"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00180300"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006389">
        <property type="entry name" value="Early_transc_mb_plasmodium"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01495">
        <property type="entry name" value="ETRAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09716">
        <property type="entry name" value="ETRAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013062989" evidence="3">
        <location>
            <begin position="25"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="208" mass="24617" checksum="F703D4016CF5FFC0" modified="2017-02-15" version="1">MKILKVFYFFNLLLVINLLESCLSKVHTSNSSKNDELQKIDHILQGREKKKKIILISCLVTGLALAIASGVGISLYIKKKKGKEQREIEEEKRDEHPEYQEDEHWVKPKKPRESDLPKKKDDLSKYKHLNEFYIFLHEIQDENIEKLNKSSLFVKENMITREFAELTVEREAKQRGLILSEADKEKAISSFRKVMYLTYRDYIKSHMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQA9</accession>
    <name>A0A1J1GQA9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fam-h protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00188200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000026">
        <property type="protein sequence ID" value="CRG94487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527305.1">
        <property type="nucleotide sequence ID" value="XM_028670565.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQA9"/>
    <dbReference type="GeneID" id="39730409"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00188200"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="187" mass="22280" checksum="FDB7B8FAC3760695" modified="2017-02-15" version="1">MNSLFFFIKYLMFAFLILILQYSNNSFFESWNIRNNSEGAFRLKTKRTLSENILKKSKSESTENLLDAYEKEEINNKQDEMEKDLIKSKAQKSNFHSHIIRKPSETKVEISNENNVNKQKVTKCKDKFISTFFFSLVFLSLPLYLVYLSHMEYFFNSKDHSEIYHFLMSHCILIISCILCLHLRRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQD1</accession>
    <name>A0A1J1GQD1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">SET domain protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00121000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526325.1">
        <property type="nucleotide sequence ID" value="XM_028674722.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729735"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00121000"/>
    <dbReference type="OMA" id="REHEYDK"/>
    <dbReference type="OrthoDB" id="616263at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042054">
        <property type="term" value="F:histone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002039">
        <property type="term" value="F:p53 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.280.10">
        <property type="entry name" value="SRA-YDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043550">
        <property type="entry name" value="EHMT1/EHMT2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036987">
        <property type="entry name" value="SRA-YDG_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46307">
        <property type="entry name" value="G9A, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46307:SF4">
        <property type="entry name" value="G9A, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50868">
        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SET" evidence="6">
        <location>
            <begin position="2019"/>
            <end position="2146"/>
        </location>
    </feature>
    <feature type="domain" description="Post-SET" evidence="7">
        <location>
            <begin position="2150"/>
            <end position="2166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="145"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="312"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="393"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="478"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1001"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1322"/>
            <end position="1342"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1376"/>
            <end position="1403"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1713"/>
            <end position="1742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="317"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="483"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="498"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="509"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="528"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1006"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1027"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1328"/>
            <end position="1337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2166" mass="254481" checksum="BE5ACD6D89644B45" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQJ6</accession>
    <name>A0A1J1GQJ6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">3'-5' exonuclease</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Werner Syndrome-like exonuclease</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00102000</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526136.1">
        <property type="nucleotide sequence ID" value="XM_028672866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQJ6"/>
    <dbReference type="GeneID" id="39729545"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00102000"/>
    <dbReference type="OrthoDB" id="1920326at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06141">
        <property type="entry name" value="WRN_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051132">
        <property type="entry name" value="3-5_Exonuclease_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13620:SF109">
        <property type="entry name" value="3'-5' EXONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13620">
        <property type="entry name" value="3-5 EXONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00474">
        <property type="entry name" value="35EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3'-5' exonuclease" evidence="10">
        <location>
            <begin position="100"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00040531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00042761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG93314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="437" mass="51723" checksum="2FAF8DE834DDBB95" modified="2017-02-15" version="1">MFSSLKKFYKCSKPYYSNKINDYFNPLKFTGIVIYVNQENVTKYEKSIIKYLKTDIVGFDTEFVIDINNSNKKFLKNFEKTNSLINNISEINTLNNIKTTNKLLEKKYQNNLINKYKNKKNINKINIFKKKKNSENTYEENKKLCLIQLSSNDICFVFNINKLKGKIPQSVKEILENDKIIKVCHDIKNDKDMFLSNNIEIKNVFDLYNYSIENFIYPPSLQSLVKIYLKKFLDKNFRLSNWLSDNLIEEQILYAALDAYASREVYMILKNQNKVDKCKLFNLNIENDSSGMKENIIGSTYVNENKNCVKTNGEETKTDLEKICDNTKNTKIRIKEIISYDNNYNEKKKERKKGYEYLEKNKSNIINNLKNEINMKCSKINNITFLEEMVFSNDSYKNVLYLKHIEKNNYLIKLSSFNYDDEINCCNVILNYINKMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQL3</accession>
    <name>A0A1J1GQL3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PTP1</name>
        <name evidence="7" type="ORF">PGAL8A_00214400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527562.1">
        <property type="nucleotide sequence ID" value="XM_028670850.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQL3"/>
    <dbReference type="GeneID" id="39730671"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00214400"/>
    <dbReference type="OMA" id="EWRYEMR"/>
    <dbReference type="OrthoDB" id="10252009at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033550">
        <property type="term" value="F:MAP kinase tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017017">
        <property type="term" value="F:MAP kinase tyrosine/serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008330">
        <property type="term" value="F:protein tyrosine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043409">
        <property type="term" value="P:negative regulation of MAPK cascade"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14498">
        <property type="entry name" value="DSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10159:SF519">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE MPK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="5">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="6">
        <location>
            <begin position="64"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG94747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="171" mass="19981" checksum="18B42C77D7FF3EC2" modified="2017-02-15" version="1">MIQILPFLYLGRSNDVDNVEILKEKGIKAFVICCTYFEYPEQKVPDGYENLRIDLEDMGLEPISSYFELSNNFIHSFISKEQAVLIYCCHGISRSSTIAIAYLMEKQNFCLNEAFNFIMKKKKICPNIGFIEQLCEYEKNLKNKITFSSKKYINWFISEMCDSNVTVDFSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQT9</accession>
    <name>A0A1J1GQT9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00222400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527642.1">
        <property type="nucleotide sequence ID" value="XM_028670939.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQT9"/>
    <dbReference type="GeneID" id="39730751"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00222400"/>
    <dbReference type="OMA" id="QNHMLNI"/>
    <dbReference type="OrthoDB" id="389739at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="305" mass="36230" checksum="C72611ECF9DDD7D9" modified="2017-02-15" version="1">MEKVISMREIITNTRKIKLHENFLEDCNLKDIFYNGLEAVNCAYNDYVNIKTWLFVISEKLFSNDYEELAYVACDALKVLLCNNRFLNVIIFKLLKKNLEKDVLKIMGICCLTVASRMQQINETTCFKEILEMSNLKNKINEFNIRQIEIDVFVSLAHSGFCFEKIVTPVNELNKIMNFLESYKNLFENNFHLFKSSSNLMLRIIYCMVPVFNMNIYNYSIVNYVLRLFIKDNEIYKYIFENLKKNYYDKEIIDISNFQNHMINIINAFKNTSIFSAKDSILNKPDTIELFEEINKRIECQWKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQZ3</accession>
    <name>A0A1J1GQZ3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glideosome associated protein with multiple membrane spans 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">GAPM1</name>
        <name evidence="2" type="ORF">PGAL8A_00235600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527772.1">
        <property type="nucleotide sequence ID" value="XM_028671083.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQZ3"/>
    <dbReference type="GeneID" id="39730884"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00235600"/>
    <dbReference type="OMA" id="EAWGWIC"/>
    <dbReference type="OrthoDB" id="328372at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021691">
        <property type="entry name" value="DUF3273"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11677">
        <property type="entry name" value="DUF3273"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="303" mass="34027" checksum="17BF22D8BDE87F57" modified="2017-02-15" version="1">MFFTYVVRPGEAPEGRGPQFEPFWDFFMNFNLRVGFLIQFISYLLLVCSVSLIGNNPFGILKFLRALPGNVGDAPIPLVLLSVGGFLLGTLLIMSFLQLTEDDSSIKQSRGYRAGTKFLLQATSMGTVSWSLSLICLMASSYYFDDPWMEEKIGAGSSWILYFSSRVIDAFCLFLYGSGCFFLEVYHSEGAGEAWGWLCGMSFLATSFLEVLGLTLFNTPSFESLDWFYCLFLGISLFFSVVWGFLFEPISHRYDVKLTQSAMRNEYYKSRNAMAYYGPAVVTANGEIDIEASAEHIPSCKKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRR6</accession>
    <name>A0A1J1GRR6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00260600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528014.1">
        <property type="nucleotide sequence ID" value="XM_028671353.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRR6"/>
    <dbReference type="GeneID" id="39731135"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00260600"/>
    <dbReference type="OMA" id="KKIQDHN"/>
    <dbReference type="OrthoDB" id="370900at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="274" mass="32336" checksum="5716CE4AD91F581E" modified="2017-02-15" version="1">MNSSLKNNEDENNYFVISFFESLSNFIKNVKIEIKDIFELLNYPCVYQNCKKKFSVSENEDFKNTLATNVISKVDKKNIENFRAYKKELHNMLQNVKIFQEKYKMDIPLMFIVENLVTLHLINEYKINNIVKKIQEHNIVMPELNSDLPDYLIHTIEVDDNENFNELLPKIRENNSLSIHNNVLKQLLESSEIKINFSKMGDINDENFNHSNRLNYISNYNVKSNGFIPFKKEENNNLPHKIEEKSNIIENIGLSEETLKLLNLLPKKRKTDID</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS09</accession>
    <name>A0A1J1GS09_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glutaredoxin-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">GRX1</name>
        <name evidence="8" type="ORF">PGAL8A_00005600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutaredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528102.1">
        <property type="nucleotide sequence ID" value="XM_028671451.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS09"/>
    <dbReference type="GeneID" id="39728578"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00005600"/>
    <dbReference type="OMA" id="IYTSPLC"/>
    <dbReference type="OrthoDB" id="44061at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015038">
        <property type="term" value="F:glutathione disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03419">
        <property type="entry name" value="GRX_GRXh_1_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011767">
        <property type="entry name" value="GLR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047185">
        <property type="entry name" value="GLRX1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011899">
        <property type="entry name" value="Glutaredoxin_euk/vir"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014025">
        <property type="entry name" value="Glutaredoxin_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02180">
        <property type="entry name" value="GRX_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46185">
        <property type="entry name" value="GLUTAREDOXIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46185:SF1">
        <property type="entry name" value="GLUTAREDOXIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00160">
        <property type="entry name" value="GLUTAREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00195">
        <property type="entry name" value="GLUTAREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="7">
        <location>
            <begin position="21"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="109" mass="12124" checksum="0542D90D6E6BE3E3" modified="2017-02-15" version="1">MGCSSEAIKKWVNQIIDENIIAVFSKTECPYCIKAISILKGFNVNSMHVAQIEKDPKVTEIQAYLKELTGKSSVPRIFINKQVVGGCDDLVKEKEEGKLLERLKNAGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS43</accession>
    <name>A0A1J1GS43_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Membrane magnesium transporter, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00006000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528106.1">
        <property type="nucleotide sequence ID" value="XM_028671456.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS43"/>
    <dbReference type="GeneID" id="39728582"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00006000"/>
    <dbReference type="OMA" id="DHFTIPY"/>
    <dbReference type="OrthoDB" id="373661at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="116" mass="13757" checksum="53D3F51A134B1DA2" modified="2017-02-15" version="1">MNDKYSVSITLLGLASLLKSGHSVYLHLNRFKLENENMENFAIPHMLVIQIILCALITMYGGSKLFLKFQNIKNDSSQNFNNHDWDKNHTRQNFRHSFNRKYFIKDYVRNYINKAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS50</accession>
    <name>A0A1J1GS50_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">asparagine synthase (glutamine-hydrolyzing)</fullName>
            <ecNumber evidence="2">6.3.5.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PGAL8A_00008800</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-aspartate + L-glutamine + ATP + H2O = L-asparagine + L-glutamate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12228"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58048"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-asparagine biosynthesis; L-asparagine from L-aspartate (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.4" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528132.1">
        <property type="nucleotide sequence ID" value="XM_028671484.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS50"/>
    <dbReference type="GeneID" id="39728610"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00008800"/>
    <dbReference type="OMA" id="GIVCAFD"/>
    <dbReference type="OrthoDB" id="409189at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00712">
        <property type="entry name" value="AsnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000031">
        <property type="entry name" value="Asparagine synthase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006426">
        <property type="entry name" value="Asn_synth_AEB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050795">
        <property type="entry name" value="Asn_Synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033738">
        <property type="entry name" value="AsnB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01536">
        <property type="entry name" value="asn_synth_AEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006949">
        <property type="entry name" value="PRK09431.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11772">
        <property type="entry name" value="ASPARAGINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11772:SF2">
        <property type="entry name" value="ASPARAGINE SYNTHETASE [GLUTAMINE-HYDROLYZING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13537">
        <property type="entry name" value="GATase_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001589">
        <property type="entry name" value="Asn_synthetase_glu-h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 11" id="KW-0061">Asparagine biosynthesis</keyword>
    <keyword evidence="6 10 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 11" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 10 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="14">
        <location>
            <begin position="2"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="active site" description="For GATase activity" evidence="11">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="357"/>
            <end position="358"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for beta-aspartyl-AMP intermediate formation" evidence="13">
        <location>
            <position position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR001589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG95321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="576" mass="66051" checksum="4D89B771F10AD336" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSC3</accession>
    <name>A0A1J1GSC3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00018000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528222.1">
        <property type="nucleotide sequence ID" value="XM_028671584.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSC3"/>
    <dbReference type="GeneID" id="39728702"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00018000"/>
    <dbReference type="OMA" id="MKDIMHI"/>
    <dbReference type="OrthoDB" id="372660at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="822" mass="97826" checksum="BF4969D6B8FBD2E2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSD4</accession>
    <name>A0A1J1GSD4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Eukaryotic translation initiation factor 3 subunit K</fullName>
            <shortName evidence="1">eIF3k</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">eIF-3 p25</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00009900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF-3 subunit K family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528143.1">
        <property type="nucleotide sequence ID" value="XM_028671496.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSD4"/>
    <dbReference type="GeneID" id="39728621"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00009900"/>
    <dbReference type="OMA" id="YPHMMFN"/>
    <dbReference type="OrthoDB" id="337745at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006446">
        <property type="term" value="P:regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.250">
        <property type="entry name" value="ARM repeat, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03010">
        <property type="entry name" value="eIF3k"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033464">
        <property type="entry name" value="CSN8_PSD8_EIF3K"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009374">
        <property type="entry name" value="eIF3k"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016020">
        <property type="entry name" value="Transl_init_fac_sub12_N_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13022">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13022:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10075">
        <property type="entry name" value="CSN8_PSD8_EIF3K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="1" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CSN8/PSMD8/EIF3K" evidence="2">
        <location>
            <begin position="67"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="234" mass="27982" checksum="4DE5FFA5934DC8A5" modified="2017-02-15" version="1">MNVKSIIEEVQAIKVLPHMMFNASKLKVLNDYVDIAFENNEYFDNEVMLTLLRLFCLYPHCYDRMAVKKILICVLYNINEIDMNIYLSLINSNLYDENIKSVVYLHDLIKKCQFKKLWDCIYNNESDNNNYDYSFLKNNNNFTFSIRKYILNSISLSFENISLKKMSEYLNIHDFSEIEKFLNENKWTIKQVNYKGEDQYICCNGNIENIQHKKNINTYFNEDNISSYITKLNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSF2</accession>
    <name>A0A1J1GSF2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Lysine--tRNA ligase</fullName>
            <ecNumber evidence="3 12">6.1.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 12">Lysyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">KRS1</name>
        <name evidence="15" type="ORF">PGAL8A_00261100</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>tRNA(Lys) + L-lysine + ATP = L-lysyl-tRNA(Lys) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:20792"/>
            <dbReference type="Rhea" id="RHEA-COMP:9696"/>
            <dbReference type="Rhea" id="RHEA-COMP:9697"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78529"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.6" evidence="3 12"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528019.1">
        <property type="nucleotide sequence ID" value="XM_028671359.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSF2"/>
    <dbReference type="GeneID" id="39731140"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00261100"/>
    <dbReference type="OMA" id="DFRNEGM"/>
    <dbReference type="OrthoDB" id="21243at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004824">
        <property type="term" value="F:lysine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006430">
        <property type="term" value="P:lysyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00775">
        <property type="entry name" value="LysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04322">
        <property type="entry name" value="LysRS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000050">
        <property type="entry name" value="Lysine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000238">
        <property type="entry name" value="Lysine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00252">
        <property type="entry name" value="Lys_tRNA_synth_class2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002313">
        <property type="entry name" value="Lys-tRNA-ligase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034762">
        <property type="entry name" value="Lys-tRNA-ligase_II_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044136">
        <property type="entry name" value="Lys-tRNA-ligase_II_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018149">
        <property type="entry name" value="Lys-tRNA-synth_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00499">
        <property type="entry name" value="lysS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001756">
        <property type="entry name" value="PRK00484.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42918:SF9">
        <property type="entry name" value="LYSINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42918">
        <property type="entry name" value="LYSYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039101">
        <property type="entry name" value="LysRS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00982">
        <property type="entry name" value="TRNASYNTHLYS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="14">
        <location>
            <begin position="248"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="48"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG95207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="580" mass="67578" checksum="9DF7598D3F298826" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSK0</accession>
    <name>A0A1J1GSK0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00270100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000039">
        <property type="protein sequence ID" value="CRG95501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528310.1">
        <property type="nucleotide sequence ID" value="XM_028671682.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSK0"/>
    <dbReference type="GeneID" id="39731233"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00270100"/>
    <dbReference type="OrthoDB" id="6362699at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="79" mass="9093" checksum="A0106369961170BA" modified="2017-02-15" version="1" fragment="single">MAFLYNDGCETSEGDFTKCFMNICEINLNKFEASYCRIERPVVDIKKASNKNLNDLSKNLFTDEYTPSNLKSRIIILSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSK8</accession>
    <name>A0A1J1GSK8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00271000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000041">
        <property type="protein sequence ID" value="CRG95509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528318.1">
        <property type="nucleotide sequence ID" value="XM_028671691.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731241"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00271000"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="637"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1298" mass="150888" checksum="F5EF6DEEAD22EFD7" modified="2017-02-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSL3</accession>
    <name>A0A1J1GSL3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">P-loop containing nucleoside triphosphate hydrolase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00005100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528097.1">
        <property type="nucleotide sequence ID" value="XM_028671446.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSL3"/>
    <dbReference type="GeneID" id="39728573"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00005100"/>
    <dbReference type="OMA" id="GHVEDDF"/>
    <dbReference type="OrthoDB" id="10262413at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22967">
        <property type="entry name" value="DD_AK7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.890.10">
        <property type="entry name" value="cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047499">
        <property type="entry name" value="DD_AK7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007858">
        <property type="entry name" value="Dpy-30_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051783">
        <property type="entry name" value="NAD(P)-dependent_oxidoreduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48079:SF6">
        <property type="entry name" value="NAD(P)-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48079">
        <property type="entry name" value="PROTEIN YEEZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13207">
        <property type="entry name" value="AAA_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05186">
        <property type="entry name" value="Dpy-30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="336"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="425"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="654"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="120"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="348"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="358"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="427"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="655"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="671"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="748"/>
            <end position="765"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1040" mass="124330" checksum="137822ADABCC03EA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSQ6</accession>
    <name>A0A1J1GSQ6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">rRNA biogenesis protein RRP5, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00276300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the crooked-neck family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528374.1">
        <property type="nucleotide sequence ID" value="XM_028671752.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSQ6"/>
    <dbReference type="GeneID" id="39731295"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00276300"/>
    <dbReference type="OMA" id="EEYAHNI"/>
    <dbReference type="OrthoDB" id="412781at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055433">
        <property type="entry name" value="HAT_Syf1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045209">
        <property type="entry name" value="Rrp5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23270">
        <property type="entry name" value="PROGRAMMED CELL DEATH PROTEIN 11 PRE-RRNA PROCESSING PROTEIN RRP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23270:SF10">
        <property type="entry name" value="PROTEIN RRP5 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23233">
        <property type="entry name" value="HAT_Syf1_CNRKL1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Pre-mRNA-splicing factor Syf1-like N-terminal HAT-repeats" evidence="7">
        <location>
            <begin position="276"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="132"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="214"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="142"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="154"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF23233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="566" mass="67763" checksum="DFC4FA57D68ED375" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSS8</accession>
    <name>A0A1J1GSS8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">U2 snRNP-associated SURP motif-containing protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SR140</name>
        <name evidence="7" type="ORF">PGAL8A_00274500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528356.1">
        <property type="nucleotide sequence ID" value="XM_028671733.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSS8"/>
    <dbReference type="GeneID" id="39731277"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00274500"/>
    <dbReference type="OrthoDB" id="377209at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.790">
        <property type="entry name" value="Surp module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006569">
        <property type="entry name" value="CID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051485">
        <property type="entry name" value="SR-CTD_assoc_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000061">
        <property type="entry name" value="Surp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035967">
        <property type="entry name" value="SWAP/Surp_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23140">
        <property type="entry name" value="RNA PROCESSING PROTEIN LD23810P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23140:SF0">
        <property type="entry name" value="U2 SNRNP-ASSOCIATED SURP MOTIF-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01805">
        <property type="entry name" value="Surp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00648">
        <property type="entry name" value="SWAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109905">
        <property type="entry name" value="Surp module (SWAP domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51391">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50128">
        <property type="entry name" value="SURP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="163"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="SURP motif" evidence="5">
        <location>
            <begin position="288"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="CID" evidence="6">
        <location>
            <begin position="364"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="113"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="369"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="642" mass="76758" checksum="BF60F52E29206501" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT86</accession>
    <name>A0A1J1GT86_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DIX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00292800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528532.1">
        <property type="nucleotide sequence ID" value="XM_028671928.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT86"/>
    <dbReference type="GeneID" id="39731461"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00292800"/>
    <dbReference type="OrthoDB" id="10007451at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016055">
        <property type="term" value="P:Wnt signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001158">
        <property type="entry name" value="DIX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038207">
        <property type="entry name" value="DIX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42509">
        <property type="entry name" value="DIX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42509:SF1">
        <property type="entry name" value="DIX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00778">
        <property type="entry name" value="DIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0879">Wnt signaling pathway</keyword>
    <feature type="domain" description="DIX" evidence="2">
        <location>
            <begin position="5"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="174" mass="20247" checksum="BF01630ED50A2478" modified="2017-02-15" version="1">MSKTTIVFYQIINDKEDKNSQNVFYISKPINTITLNDIKNEFPLIGTYHFRFKILLNNTHVWVDINDDSSSIPSLNSCIYAKVLRLSWLDHKKENSNLNEKISNEQNIEKQCESNKIISGSKEKNTYDNIEVQKSKSSIDMLLFETTSNKSTSANTIKRNDNTKDQNYFDLMFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTB8</accession>
    <name>A0A1J1GTB8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fam-i protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00267600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000036">
        <property type="protein sequence ID" value="CRG95473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528283.1">
        <property type="nucleotide sequence ID" value="XM_028671652.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTB8"/>
    <dbReference type="GeneID" id="39731205"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00267600"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="93" mass="10525" checksum="85A9A05DB4C59E27" modified="2017-02-15" version="1" fragment="single">MDLNLSDAINIDSNKRLNEGDSTTGFTHRTIKDATVTKRENPLHNCFLKLRDAIKKPSKDINLDSATSKNLLHKKSLSIFQLVIIIISFLRFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTN3</accession>
    <name>A0A1J1GTN3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00205900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527477.1">
        <property type="nucleotide sequence ID" value="XM_028670757.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTN3"/>
    <dbReference type="GeneID" id="39730586"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00205900"/>
    <dbReference type="OMA" id="CKQYNDK"/>
    <dbReference type="OrthoDB" id="366387at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="172"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="363" mass="43880" checksum="EA7DED93E320E9EE" modified="2017-02-15" version="1">MYYLKKGKMENMSVIIKKNDINNLNSYKEEKNYNNNNMRINDANINNDLFYPFYQKFNQIFEFIKDTKENKNDLEDEIDENLIKTLYNLCHEFINYIKNINNFGNLNLNENDQELIIESYEKFVRQCKEYNDKPKVKQLENEISNLLDLLFNNTSEAVNTLFSADSFFVDHVENLKLRLNERNQKIEFEKERLKKLELEEKVEEFDETFEENKKKNNEMDETISKIKKEINKLNEKIEKYDNYMKKKRKEIDIDFSDALDGKERIKILEESIKTIERNMKTTQLSPLKIIEKTPYYIIFEFTTPRNIMQFRINNYESENVQVEVNPYDQNILSYINENIKKCKDISEVTYLIKEAIYLNFLDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTY4</accession>
    <name>A0A1J1GTY4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Signal recognition particle 14 kDa protein</fullName>
            <shortName evidence="7">SRP14</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00318500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterodimer with SRP9; binds RNA as heterodimer. Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the SRP14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528780.1">
        <property type="nucleotide sequence ID" value="XM_028672205.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTY4"/>
    <dbReference type="GeneID" id="39731718"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00318500"/>
    <dbReference type="OMA" id="IWITMKK"/>
    <dbReference type="OrthoDB" id="19209at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030942">
        <property type="term" value="F:endoplasmic reticulum signal peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.720.10">
        <property type="entry name" value="Signal recognition particle alu RNA binding heterodimer, srp9/1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003210">
        <property type="entry name" value="Signal_recog_particle_SRP14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009018">
        <property type="entry name" value="Signal_recog_particle_SRP9/14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12013">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 14 KD PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02290">
        <property type="entry name" value="SRP14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54762">
        <property type="entry name" value="Signal recognition particle alu RNA binding heterodimer, SRP9/14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0733">Signal recognition particle</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU368100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="103" mass="12018" checksum="EF6E023EF707220E" modified="2017-02-15" version="1">MVLLSNNLFIDELKKLCGEVEGKKKTSIWITMKKVKRSDVKNIGHKKDTNEKKNKKINKDDNKCSKKYMCLIRATDGKKKKISTHVYDNVINFSQEINNIIKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUG2</accession>
    <name>A0A1J1GUG2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phenylalanine--tRNA ligase beta subunit</fullName>
            <ecNumber evidence="4">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Phenylalanyl-tRNA synthetase beta subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">PGAL8A_00331300</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>tRNA(Phe) + L-phenylalanine + ATP = L-phenylalanyl-tRNA(Phe) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528903.1">
        <property type="nucleotide sequence ID" value="XM_028672341.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUG2"/>
    <dbReference type="GeneID" id="39731843"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00331300"/>
    <dbReference type="OMA" id="FPGRCAN"/>
    <dbReference type="OrthoDB" id="1698572at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009328">
        <property type="term" value="C:phenylalanine-tRNA ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00769">
        <property type="entry name" value="PheRS_beta_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.40.10:FF:000003">
        <property type="entry name" value="Phenylalanine--tRNA ligase beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.56.10:FF:000009">
        <property type="entry name" value="Phenylalanine-tRNA ligase, beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.56.10:FF:000012">
        <property type="entry name" value="Phenylalanine-tRNA ligase, beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.56.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.40.10">
        <property type="entry name" value="Phenylalanyl-trna Synthetase, Chain B, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005146">
        <property type="entry name" value="B3/B4_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045060">
        <property type="entry name" value="Phe-tRNA-ligase_IIc_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004531">
        <property type="entry name" value="Phe-tRNA-synth_IIc_bsu_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020825">
        <property type="entry name" value="Phe-tRNA_synthase-like_B3/B4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041616">
        <property type="entry name" value="PheRS_beta_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040659">
        <property type="entry name" value="PhetRS_B1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005147">
        <property type="entry name" value="tRNA_synthase_B5-dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00471">
        <property type="entry name" value="pheT_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10947:SF0">
        <property type="entry name" value="PHENYLALANINE--TRNA LIGASE BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10947">
        <property type="entry name" value="PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN AND LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03483">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03484">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18262">
        <property type="entry name" value="PhetRS_B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17759">
        <property type="entry name" value="tRNA_synthFbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00873">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00874">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56037">
        <property type="entry name" value="PheT/TilS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="Putative DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51483">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 17" id="KW-0436">Ligase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B5" evidence="16">
        <location>
            <begin position="297"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00033189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="CRG96098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="617" mass="71944" checksum="248609F44BBC2932" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUJ2</accession>
    <name>A0A1J1GUJ2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sortilin, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00211000</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS10-related sortilin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527528.1">
        <property type="nucleotide sequence ID" value="XM_028670813.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUJ2"/>
    <dbReference type="GeneID" id="39730637"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00211000"/>
    <dbReference type="OMA" id="FAPFYSV"/>
    <dbReference type="OrthoDB" id="443634at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006892">
        <property type="term" value="P:post-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.70.80:FF:000005">
        <property type="entry name" value="Sortilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.270:FF:000006">
        <property type="entry name" value="Sortilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036278">
        <property type="entry name" value="Sialidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031777">
        <property type="entry name" value="Sortilin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031778">
        <property type="entry name" value="Sortilin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006581">
        <property type="entry name" value="VPS10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050310">
        <property type="entry name" value="VPS10-sortilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12106">
        <property type="entry name" value="SORTILIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12106:SF27">
        <property type="entry name" value="SORTILIN-RELATED RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15902">
        <property type="entry name" value="Sortilin-Vps10"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15901">
        <property type="entry name" value="Sortilin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00602">
        <property type="entry name" value="VPS10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110296">
        <property type="entry name" value="Oligoxyloglucan reducing end-specific cellobiohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="Sialidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="762"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="domain" description="VPS10" evidence="9">
        <location>
            <begin position="79"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="829"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="844"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="858"/>
            <end position="884"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG94713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="884" mass="100959" checksum="66EFC3CF8B595D41" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUT7</accession>
    <name>A0A1J1GUT7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00328100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000056">
        <property type="protein sequence ID" value="CRG96068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528873.1">
        <property type="nucleotide sequence ID" value="XM_028672307.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUT7"/>
    <dbReference type="GeneID" id="39731811"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00328100"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="646"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="366"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="553"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="416"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="442"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="923"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="923" mass="104422" checksum="ECD51FCD1FA4028A" modified="2017-02-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUV7</accession>
    <name>A0A1J1GUV7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00354700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529134.1">
        <property type="nucleotide sequence ID" value="XM_028672597.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUV7"/>
    <dbReference type="GeneID" id="39732077"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00354700"/>
    <dbReference type="OMA" id="INYSIYC"/>
    <dbReference type="OrthoDB" id="386413at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="437" mass="51277" checksum="049A3C14E1E83ACD" modified="2017-02-15" version="1">MWNLINYNIDTETNSKFTFWNIFGYEEKQIQNEINDEINRNEDKNNLKIEDNLGNDLVEICDNSISDKKEKKKKKKIEKIKENRNKSPFLSDLSSYADYCTSDEGNENYKLNLKNDEIISNDKNDENCLITSKEKLIEKEEKVNKREIDINADNEVNTNKVENVNKEDNTNKVENTNNDENVNKEENTNKVENADKVENADNEENANKVENENKVENENKVENENKVENADNKENENIMSSTNEWFFEKIKGILDPSINQESISELITNKYNSFNEANAGIFDLLENLLLRSNTQEKMELKKSQKSHFFYDHHNSVDDSFNDHYNFINYSIYCINKELSATVELEATKMMKIYNNAYNSFKKEINFNDDIYVDLLNEGEEFSTLIVDENDKIKKRILKIEFLILININSDNYNNIIESHNVPTPKLNLEEIFKINVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUX5</accession>
    <name>A0A1J1GUX5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein mL54</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00350300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the mitochondrion-specific ribosomal protein mL54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529090.1">
        <property type="nucleotide sequence ID" value="XM_028672549.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUX5"/>
    <dbReference type="GeneID" id="39732033"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00350300"/>
    <dbReference type="OrthoDB" id="10252718at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013870">
        <property type="entry name" value="Ribosomal_mL54"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28595">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L54, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28595:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08561">
        <property type="entry name" value="Ribosomal_L37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="148" mass="17626" checksum="E33574FD30AB28A3" modified="2017-02-15" version="1">MLQLYKNDILFTSKKSIFPIYLRNIFISKCKLAPKVKSGKKGQDKKDTENITESSEKAHVFNIYNTVEKDHEILPDYAYPKWLWKLEKPLKSYGELALMFLYGKDIENATAEDYHRFRRLHNKNLIKLNNLRLKKSKRSTVKPIFWDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUZ9</accession>
    <name>A0A1J1GUZ9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Pre-mRNA-splicing factor 38</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PRP38A</name>
        <name evidence="9" type="ORF">PGAL8A_00360100</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for pre-mRNA splicing.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the PRP38 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529182.1">
        <property type="nucleotide sequence ID" value="XM_028672651.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUZ9"/>
    <dbReference type="GeneID" id="39732131"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00360100"/>
    <dbReference type="OMA" id="HTYWKEQ"/>
    <dbReference type="OrthoDB" id="190958at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005037">
        <property type="entry name" value="PRP38"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23142">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR 38A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03371">
        <property type="entry name" value="PRP38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5 7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0747">Spliceosome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="228"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="341"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="238"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="280"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="300"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="345"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="363"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG96377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="399" mass="48023" checksum="08682FD4D9CD1019" modified="2017-02-15" version="1">MANRTDVTAIKIFGSNPQYLISNIIRSKIYESQYWKEKCFALTSESIIDQAINLKYIGGTYGGNRKPTRFLCLILKLLQIQPDKDIVYEYIKNEEFIYLRALGIFYLRLIGKSLEVYKNLEPVLFDYRKVRMRLQDGTFQKIYMDEFVDNCLILNNYLDVDFPTLTKRQILEENNLLEKRNLEYYKELLNISSDNELLENEINKNKSNLSQNDNQESDLNRSNIFNKVCTYDNDGNHREKKKKKKEEKKKKQKYKEKESRKKMKKKENTYYNYKKKKYSSENQDSYSTDSNKYDRKRRKNYVDKDDYDKKNKRKEKILKVKKGEENDIYKKKKEKKIFFNLKKNKNTESSEKSDTSYGKYVKKKENNKNISIHDENKKDDISIDEWNKIRKNLGMKPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV40</accession>
    <name>A0A1J1GV40_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00354800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529135.1">
        <property type="nucleotide sequence ID" value="XM_028672598.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732078"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00354800"/>
    <dbReference type="OrthoDB" id="8069108at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="933"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1025"/>
            <end position="1237"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1548"/>
            <end position="1596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1037"/>
            <end position="1165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1172"/>
            <end position="1237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2363" mass="283574" checksum="2E7AB2D094346EAA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVC7</accession>
    <name>A0A1J1GVC7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00001500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528061.1">
        <property type="nucleotide sequence ID" value="XM_028671405.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVC7"/>
    <dbReference type="GeneID" id="39728537"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00001500"/>
    <dbReference type="OMA" id="PSPINHF"/>
    <dbReference type="OrthoDB" id="365006at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="370" mass="44740" checksum="DA077ACCCB99EFD3" modified="2017-02-15" version="1">MIKIIKRQIYYSCEKKKYYTNRLYKKVCNNCFNLNINNLSKCVYCDHNINDNDIRLIKNNIFTDIINVRKECKYIDEKSVKTNFVPLLNNVEIDDRYIHIKNGLINNCNRLYVYYNCYDYIIMNNPYSNSCINLIVLFKGITYDVKNLKRKNINCLLHLYNYIYFIIDIFLYFLIISKGKYVHYKYMYNKSTYVDKDYNEEIVEILLELNKIIKERKKNVVVDNINSKKKYLENVNEENIIEKLNENYEDIYKDILRNTDKSTLNNFFKKLEDKNVKKKIKTLKKHLYVGCSYPSPINHFSMQILFPPFSNYNFFTFPFYFSIQKILCDLYVYGHVKNYNHSEVIKNIYNNKLIKEIKESDTSSKDILQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVL1</accession>
    <name>A0A1J1GVL1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GAF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00373100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529311.1">
        <property type="nucleotide sequence ID" value="XM_028672794.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVL1"/>
    <dbReference type="GeneID" id="39732261"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00373100"/>
    <dbReference type="OMA" id="NNEMNLH"/>
    <dbReference type="OrthoDB" id="430821at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019537">
        <property type="entry name" value="TMEM65"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21706">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21706:SF15">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10507">
        <property type="entry name" value="TMEM65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="265"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="294"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="319"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="357"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="GAF" evidence="6">
        <location>
            <begin position="484"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="587" mass="69030" checksum="AE5145A68CDC1B1C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVM1</accession>
    <name>A0A1J1GVM1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Replication protein A1, small, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00417300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529396.1">
        <property type="nucleotide sequence ID" value="XM_028672889.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVM1"/>
    <dbReference type="GeneID" id="39732704"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00417300"/>
    <dbReference type="OMA" id="VIRAVFW"/>
    <dbReference type="OrthoDB" id="1751331at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04474">
        <property type="entry name" value="RPA1_DBD_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04475">
        <property type="entry name" value="RPA1_DBD_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000209">
        <property type="entry name" value="Replication protein A1, small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013955">
        <property type="entry name" value="Rep_factor-A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031657">
        <property type="entry name" value="REPA_OB_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47165">
        <property type="entry name" value="OS03G0429900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47165:SF4">
        <property type="entry name" value="OS03G0429900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08646">
        <property type="entry name" value="Rep_fac-A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16900">
        <property type="entry name" value="REPA_OB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Replication protein A OB" evidence="3">
        <location>
            <begin position="132"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="Replication factor A C-terminal" evidence="2">
        <location>
            <begin position="307"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="484" mass="56357" checksum="D72515891C646020" modified="2017-02-15" version="1">MSENDLLFRISQITTYVSKWIIKAKVVNKTKLSTFKNNNSFFSIDITDVHGDSISCKFWGSSADKWFNNIELKKVYIFSKGRVSIANPKYNTVKHKYELTFNEDSEIHEVKDDGEIKIQKKISLVNLRDIKIATKETPFTADLIGIVKHIGAISNLKTKQGNDITKQNIIIVDDTKHSFEISFWDTNVNLIKDEIQENEIYIFTNISIRNWNDMKNGTFGVTSSIEKMETLNEELKGKCAKILQWYNTTGKYEQFTNMRNILSNDVSQNADKYYALSDVNDVLSKISGTYTLVGRIKRIYWKSKENEHRFYYPACTKCKKKLLSSGQDNNLDSNYNNTNEEDNVVYSCMNCDENNVKPFYNYTFNFLFMDFSGSINLRAFSDEGYNLLGKKAEELKNLDDDTLDYLFNYEFLYKEYKVVVRVNQKVYNGIERVNFTAMRIFPLRHSDISYLLNEIQLLLTNNNTPSKNKRALNDDTNDTKKQKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW20</accession>
    <name>A0A1J1GW20_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAA35-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00424200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529466.1">
        <property type="nucleotide sequence ID" value="XM_028672966.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW20"/>
    <dbReference type="GeneID" id="39732774"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00424200"/>
    <dbReference type="OMA" id="DFLMIYF"/>
    <dbReference type="OrthoDB" id="376025at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031417">
        <property type="term" value="C:NatC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057983">
        <property type="entry name" value="NAA35-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007244">
        <property type="entry name" value="Naa35_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21373">
        <property type="entry name" value="GLUCOSE REPRESSIBLE PROTEIN MAK10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21373:SF0">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 35, NATC AUXILIARY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04112">
        <property type="entry name" value="Mak10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="935"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="domain" description="NAA35-like N-terminal" evidence="3">
        <location>
            <begin position="26"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="693"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="693"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="706"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="762"/>
            <end position="771"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1151" mass="139347" checksum="2CE7D26BE0C462EB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW28</accession>
    <name>A0A1J1GW28_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Subpellicular microtubule protein 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SPM1</name>
        <name evidence="3" type="ORF">PGAL8A_00422300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAM154 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529447.1">
        <property type="nucleotide sequence ID" value="XM_028672945.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW28"/>
    <dbReference type="GeneID" id="39732755"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00422300"/>
    <dbReference type="OMA" id="PRCICEI"/>
    <dbReference type="OrthoDB" id="365640at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033336">
        <property type="entry name" value="SAXO1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31516">
        <property type="entry name" value="STABILIZER OF AXONEMAL MICROTUBULES 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31516:SF17">
        <property type="entry name" value="STABILIZER OF AXONEMAL MICROTUBULES 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="95"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="220"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="424" mass="48358" checksum="68216DD0109008B6" modified="2017-02-15" version="1">MEIVAEKPKVQFNFFVDEHENNKDPNYSKYIKDYNIRNEPGSYAHRKLSLGRNSEQRRKDSPSKKLGLCVDEICTCGFHKCPKIIKPQPFEGESNYRSEFGPKPLPVLPPRVEQKPPKSLPFEGESNYRSEFGPKPLPILPPRVEQKPPKSLPFEGESNYRSEFGPKPLPALPPRVEQKLPKSLPFEGESNYRSEFGPKPLPALPPKVETKLVKSLPFEGESNYRSEFGPKPLPVLPPRVEQKPPKSLPFEGESNYRIEFGPKPLPPLPPRSETKLIKSLPFEGESNYRSEFGPKPLPVLPPRVEQKPPKSLPFEGESNYRSEFGPKPLPVLPPRVEQKPPKSLPFEGESNYRSEFGPKPLPTLPPKPEVKLVKPLAFEGESSYRTEYTRKIIPVCPVTLLPQYPAPTYPSQHVFWDPEKKTWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW79</accession>
    <name>A0A1J1GW79_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10 11">Tubulin alpha chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PGAL8A_00416200</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 11">Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="2 11">Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the tubulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529385.1">
        <property type="nucleotide sequence ID" value="XM_028672876.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW79"/>
    <dbReference type="GeneID" id="39732693"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00416200"/>
    <dbReference type="OMA" id="EVRCGAY"/>
    <dbReference type="OrthoDB" id="6049624at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02186">
        <property type="entry name" value="alpha_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.600:FF:000005">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.20:FF:000001">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000004">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002452">
        <property type="entry name" value="Alpha_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01162">
        <property type="entry name" value="ALPHATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11" id="KW-0493">Microtubule</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="13">
        <location>
            <begin position="49"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="14">
        <location>
            <begin position="248"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="432"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00071544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG96581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="453" mass="50267" checksum="FC288A545989C1C9" modified="2017-02-15" version="1">MREVISIHVGQAGIQVGNACWELFCLEHGIQPDGQMPSDKAARANDDAFNTFFSETGAGKHVPRCVFVDLEPTVVDEVRTGTYRQLFHPEQLISGKEDAANNFARGHYTIGKEVIDVCLDRIRKLADNCTGLQGFLMFSAVGGGTGSGFGCLMLERLSVDYGKKSKLNFCCWPSPQVSTAVVEPYNSVLSTHSLLEHTDVAIMLDNEAIYDICRRNLDIERPTYTNLNRLIAQVISSLTASLRFDGALNVDVTEFQTNLVPYPRIHFMLSSYAPVVSAEKAYHEQLSVSEITNSAFEPANMMAKCDPRHGKYMACCLMYRGDVVPKDVNAAVATIKTKRTIQFVDWCPTGFKCGINYQPPTVVPGGDLAKVMRAVCMISNSTAIAEVFSRMDQKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGIESNEGEGEDEGYEADY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW96</accession>
    <name>A0A1J1GW96_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytochrome c oxidase subunit 6B, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00440800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529630.1">
        <property type="nucleotide sequence ID" value="XM_028673148.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW96"/>
    <dbReference type="GeneID" id="39732941"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00440800"/>
    <dbReference type="OMA" id="NEYREMG"/>
    <dbReference type="OrthoDB" id="1107506at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00926">
        <property type="entry name" value="Cyt_c_Oxidase_VIb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.140">
        <property type="entry name" value="Cytochrome c oxidase, subunit VIb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048280">
        <property type="entry name" value="COX6B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036549">
        <property type="entry name" value="CX6/COA6-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02297">
        <property type="entry name" value="COX6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47694">
        <property type="entry name" value="Cytochrome c oxidase subunit h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="103" mass="12380" checksum="7FE375A14C440E86" modified="2017-02-15" version="1">MSDLNYLSYKFIKNYDELTSQNPHASDPRFLQINQHNHCVYRYTLFCRCARELGEDDPRCKFQYYRAQIACTAEQLEEWDDHRQKGTCVMDTLPDRLTAHLRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWE1</accession>
    <name>A0A1J1GWE1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00421700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529441.1">
        <property type="nucleotide sequence ID" value="XM_028672938.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWE1"/>
    <dbReference type="GeneID" id="39732749"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00421700"/>
    <dbReference type="OrthoDB" id="372697at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="726" mass="88750" checksum="45247E3AAA3906F6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWJ5</accession>
    <name>A0A1J1GWJ5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">rRNA adenine N(6)-methyltransferase</fullName>
            <ecNumber evidence="7">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00287400</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528485.1">
        <property type="nucleotide sequence ID" value="XM_028671876.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWJ5"/>
    <dbReference type="GeneID" id="39731407"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00287400"/>
    <dbReference type="OMA" id="GSEAYCR"/>
    <dbReference type="OrthoDB" id="74991at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000179">
        <property type="term" value="F:rRNA (adenine-N6,N6-)-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000081">
        <property type="entry name" value="rRNA adenine N(6)-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00607">
        <property type="entry name" value="16SrRNA_methyltr_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011530">
        <property type="entry name" value="rRNA_adenine_dimethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00755">
        <property type="entry name" value="ksgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="DIMETHYLADENOSINE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727:SF7">
        <property type="entry name" value="DIMETHYLADENOSINE TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51689">
        <property type="entry name" value="SAM_RNA_A_N6_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 7" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4 6 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribosomal RNA adenine methylase transferase N-terminal" evidence="8">
        <location>
            <begin position="82"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG95677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="379" mass="44117" checksum="E01108C2649D30DE" modified="2017-02-15" version="1">MICRKVIFNNSLKLLTNNIKMKVNKAYHTNNKSTKILKNVNEMINKKNNKRNISTTKIKNGNKMNMILYKKHGQHLLKNPGILDKIIMAAKIKSSDIVLEIGCGTGNLTIKLLPIAKKVITIDIDARMISEVKKRCLYEGYNNLEVYEGDAIKTVFPKFDICTANIPYKISSPLIFKLIAHRPLFKCAVLMFQKEFAERMLANVGDSNYSRLTINVRLFCKVIKICNVNRSSFNPPPKVDSIIVKLIPKETNFLTNFDEWDNLLRICFSRKRKTLHAIFKRNAVLNMLEHNYKNWCTFNKKVPVNYPFKNYCLDILKDLDMSEKRSINLDENDFLKLLLEFNKKGIHFFNISNVKNSEIYNIHLDDEEDNEQELNEKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWL2</accession>
    <name>A0A1J1GWL2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Enkurin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00440900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529631.1">
        <property type="nucleotide sequence ID" value="XM_028673149.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWL2"/>
    <dbReference type="GeneID" id="39732942"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00440900"/>
    <dbReference type="OMA" id="KEDKNYM"/>
    <dbReference type="OrthoDB" id="372982at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027012">
        <property type="entry name" value="Enkurin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13864">
        <property type="entry name" value="Enkurin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enkurin" evidence="3">
        <location>
            <begin position="291"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="125"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="327"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="126"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="181"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="193"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="253"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="378" mass="45644" checksum="1416C1EB1351438F" modified="2017-02-15" version="1">MKKDNLSENVRRVLEKKEKKKLKEEKELYKATQVISSQNNILRKLIAQKQSSSTSFVNQLKNINKSLPQTKSKNEKNYMKENRLKIQEKISLQKKLLEKEEEIKNKKPFKMKKFEKVTSKIAKTLRKNEQENENKKREDIEKENTKVEKEEINREILEENEGEEYEEGEECEEGEECGEEGFEKVKEYKEESNEGEYEDEEGEVEIEEEEEEEYEYEETDQEYEEVEEMEYHEDEEVGEEEEFEEVEYEEETNEKRDVEKTEKSIIDKLKKKENNVKYENVRKEKLHKNYGKLPNYILKKKKDVTDEYADIPKGYRVLKNDERNFVLKELHSQLKEINEEYKNNKDKIKKIELGKKLKEIKESIELFSNPYVLVDENF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWM8</accession>
    <name>A0A1J1GWM8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00446000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529682.1">
        <property type="nucleotide sequence ID" value="XM_028673206.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWM8"/>
    <dbReference type="GeneID" id="39732993"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00446000"/>
    <dbReference type="OMA" id="FQYMNAK"/>
    <dbReference type="OrthoDB" id="377807at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="164" mass="19600" checksum="F1541B314CB32D0D" modified="2017-02-15" version="1">MKNNKDKRFDILPPPLEKINKKNENFTKVEKKENSNLFNGNFVNVTEKNTHMQINLNDIKKNDNSEIKKENSYISQKYSNIILNSDEINMIISRNNNFKDLIENKKVNDFMNDYLTNPLDAIKKYQKDDKILKFLEILFQYMNAKSDHIHLKNLSKNFSFQKKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWR1</accession>
    <name>A0A1J1GWR1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Plasmodium RESA N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00265600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000034">
        <property type="protein sequence ID" value="CRG95453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528264.1">
        <property type="nucleotide sequence ID" value="XM_028671630.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWR1"/>
    <dbReference type="GeneID" id="39731185"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00265600"/>
    <dbReference type="OMA" id="ENEAPYT"/>
    <dbReference type="OrthoDB" id="10541003at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012881969" description="Plasmodium RESA N-terminal domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="260" mass="31143" checksum="3C1113858FAA740A" modified="2017-02-15" version="1">MNISKLFYFFIYLIVVNIEVPCLSMQADAPFKGDSSNLESNNDTNTEVNSENEAPYTVINDLEKYINDIVLKGFNNSSPNKKKDLLKHREGLKNVIHEIIKRKHKISINQRDYIVTKAIYELLKGSLEFMEDIDQEKKDIKNRCFWMKEYHDSVRNSEWHDLIKIMKDEFTIRETPEDLTNNEKEELWEMWYSNLMKRKMEDELTQTTWFINMMDQQETESSFKTFFDSSSLSWNSYKSYLISEMNKFLTRETMKRSKMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX94</accession>
    <name>A0A1J1GX94_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00313000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528725.1">
        <property type="nucleotide sequence ID" value="XM_028672142.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX94"/>
    <dbReference type="GeneID" id="39731663"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00313000"/>
    <dbReference type="OMA" id="THRIYYC"/>
    <dbReference type="OrthoDB" id="9977870at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="334"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1097" mass="132120" checksum="275B4DC215DA52EF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXA7</accession>
    <name>A0A1J1GXA7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">mRNA processing protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00446100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529683.1">
        <property type="nucleotide sequence ID" value="XM_028673207.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXA7"/>
    <dbReference type="GeneID" id="39732994"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00446100"/>
    <dbReference type="OMA" id="INNMICK"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025742">
        <property type="entry name" value="CSTF2_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031721">
        <property type="entry name" value="Partial_CstF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45735">
        <property type="entry name" value="CLEAVAGE STIMULATION FACTOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45735:SF2">
        <property type="entry name" value="CLEAVAGE STIMULATION FACTOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14327">
        <property type="entry name" value="CSTF2_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15861">
        <property type="entry name" value="partial_CstF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="2">
        <location>
            <begin position="7"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="743" mass="87040" checksum="8EA5ACE8353F9A0B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXB1</accession>
    <name>A0A1J1GXB1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00314600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528741.1">
        <property type="nucleotide sequence ID" value="XM_028672160.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXB1"/>
    <dbReference type="GeneID" id="39731679"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00314600"/>
    <dbReference type="OMA" id="CNAVVFE"/>
    <dbReference type="OrthoDB" id="372150at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="399" mass="47154" checksum="DDA6CD0440A57B6E" modified="2017-02-15" version="1">MNNFQSKLNKKYSSKYKNKQIENKNKRKLLQLRNGHFRRIVDNEVISKNSSLPLSCTCICATPRTEENNIISSNGKINNRYNSSERSEKFENKEQIDKKSYFSKNYNKVNYVDELNSDKSEKLQNEKTIDHPSIGTISDISFTQTSKKSDDNASIIGEIETEKENKYSASSTENEEEKEKIEKKKKKEKIEEKKKEKIEEKEKEKIEEKEKEKIEDESFNDDYEFKDDIKEDETKNKGDTSNDNKLIPPSKTLMKGIKANIYFLSNKEMVEVLMCYNYNCNALIFEKDNFLRYLYLKSINNFILNERMIEGLCNKENIKYVLACNSIVIESSDFLKPLIVEFASSMVKKIFVKHMKLTSQQQWDMKKYNEYLEELDPSEKLRLRKVERFHSYNMLVTNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXB8</accession>
    <name>A0A1J1GXB8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Atypical protein kinase, ABC-1 family, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00286100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528472.1">
        <property type="nucleotide sequence ID" value="XM_028671861.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731394"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00286100"/>
    <dbReference type="OMA" id="IDWGLIK"/>
    <dbReference type="OrthoDB" id="427480at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05121">
        <property type="entry name" value="ABC1_ADCK3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="entry name" value="DD-peptidase/beta-lactamase superfamily"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051130">
        <property type="entry name" value="Mito_struct-func_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173">
        <property type="entry name" value="ABC1 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173:SF3">
        <property type="entry name" value="ABC1 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="beta-lactamase/transpeptidase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="3">
        <location>
            <begin position="89"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="808"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="544"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="743"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="819"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="845"/>
            <end position="855"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1916" mass="227368" checksum="D9EE42C291A0012A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXC7</accession>
    <name>A0A1J1GXC7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">S-adenosyl-L-methionine-dependent methyltransferase, putative</fullName>
            <ecNumber evidence="7">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00479600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530020.1">
        <property type="nucleotide sequence ID" value="XM_028673582.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXC7"/>
    <dbReference type="GeneID" id="39733329"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00479600"/>
    <dbReference type="OMA" id="MVIVDVC"/>
    <dbReference type="OrthoDB" id="435282at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049560">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807:SF4">
        <property type="entry name" value="28S RRNA (CYTOSINE-C(5))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807">
        <property type="entry name" value="NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM-dependent MTase RsmB/NOP-type" evidence="6">
        <location>
            <begin position="98"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="433"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="500" mass="58595" checksum="A473C1F82113B46B" modified="2017-02-15" version="1">MSFLYRKAAQMLLKCSKGEGIKEVLLEKEDKSVKKLYSILYNALEDLNILDKIYNIYLSKICKNKFLGIILLSVLVHRHKIDGGGKLKREIQKKEKEILNFYKKIQGESYNNNILQTKIIWKYFLIYGNDISIKEELTKSLQIVQDEDIKNLYKINNDKVKMLIDSSFYRENKIRIIDKTSCLVVKAGHIKKGMVIVDICSSPGSKAIFSLISLKKKGYLICVEKNKKRCFTLLNEILKIGEYDGLYLNERFNESEKIALNKHNFLNNKKHNIYYIKHKHNELTIKIYNCDFLNLSSEDFPDNIDVVFIDPSCSSSGMPDFVYKRNIENIFSDKNEKHDRSIMIKTNKTKNEKNTENINKFSNISKMKNINELYNRKEESKNCISETMSKSMIPKVPSIFQDKVKKLSDFQKQILTHALVKLKGSNTFIYSTCSLFEEENEQVIHEVLQKNSDFYLKKAGKDKFLYNNYKYDFSKKCVRTFPEKDLCRGIFISKICRKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXD5</accession>
    <name>A0A1J1GXD5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00317000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528765.1">
        <property type="nucleotide sequence ID" value="XM_028672186.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXD5"/>
    <dbReference type="GeneID" id="39731703"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00317000"/>
    <dbReference type="OMA" id="YLFWKEE"/>
    <dbReference type="OrthoDB" id="365900at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="392"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="426"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="685" mass="80805" checksum="3374FAFEE96108DB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXK4</accession>
    <name>A0A1J1GXK4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00476700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529991.1">
        <property type="nucleotide sequence ID" value="XM_028673550.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXK4"/>
    <dbReference type="GeneID" id="39733300"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00476700"/>
    <dbReference type="OMA" id="FNIHHEE"/>
    <dbReference type="OrthoDB" id="378833at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="484" mass="57203" checksum="0F29003CFC58BC9E" modified="2017-02-15" version="1">MSNLTFSEEKYIKLINLAKKLEECQKDLLQYQKVEIINKCNNTNLPYDINSSKFKIKNVNKKHKIKNSILRKNTDKRTQTGASTFLQHKEFPKSNKLKADVTSRKINDNKNLCILKNKNIGVYNENQKKKNYITKFIKSESLDRNKGEKINLKESSFTNFCRKEVSEKKHLINHFDEKKKKKNIFVKKDKNILSSFKNTLNNFKKTNKVVNPNIKHSDKKTKKKKTLREKKNTNEKENKFFYNRKCKDNTNVNNLKLKINNHFGNIHKVRSSLTSKLPTHYYSEKTKYPHKHSLSCMNYGRNISLCTKDISKNHNIKLMKKYKNNTKTHNMYNNKLFLKKCKLDVKRKSTYNSNMKNDLSKYISYTNNCKNSNFKEKKSLLNKMNLLSKILNPSRNNISLSKRTSHFITNKNGNNYSEKHNTKKILTQKHSMKEKNDKNCTNINAKACKELLKYLNRSSFIIFTKNHKKKSLKSKILKNKILNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXU1</accession>
    <name>A0A1J1GXU1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">THUMP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00469900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529921.1">
        <property type="nucleotide sequence ID" value="XM_028673472.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXU1"/>
    <dbReference type="GeneID" id="39733232"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00469900"/>
    <dbReference type="OMA" id="ICKPHLS"/>
    <dbReference type="OrthoDB" id="367221at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2300.10">
        <property type="entry name" value="THUMP superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040183">
        <property type="entry name" value="THUMPD1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13452">
        <property type="entry name" value="THUMP DOMAIN CONTAINING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13452:SF10">
        <property type="entry name" value="THUMP DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143437">
        <property type="entry name" value="THUMP domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="418" mass="48903" checksum="AE226DABD7831264" modified="2017-02-15" version="1">MEYEKVKRTNQFIFCSSKHASKRRKILTNNCKGILISPVNPRKMGAAIKEFLNFLKINYPNSYENDETEDNENNVKFDSEMKSSNVEKQLNDEISKINSAYNRFSPLRYIVKNFALIKFNDINDKNPSDIVTQIFLCVQKKNEKYRLRNICKIIPFDYICKPHLSPFIKTILPLIKENFIDGICAKENFTVSHIMKLLNITGEKEKEPEEIEIEGETKNEDTEEKNGYNEKEIKEKEDNEKEIKDKEDNEKKIKDNEDNEKEIKDNEDNEKEIKDNEDNEKENSTKGSEDNEKEYEEKEDSEKKNATKKNEDSVKENEERKNEDNEKKIQNTTKDIKNKSNKKVSWGLVYKCSNTKTLTKKDVLAVLDNCIGNNYCVNLTKPDLAIVVYVNEIMCGISIIKDYDKTRKFNISSFNEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXV0</accession>
    <name>A0A1J1GXV0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">THO complex subunit 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">THO2</name>
        <name evidence="4" type="ORF">PGAL8A_00470700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529929.1">
        <property type="nucleotide sequence ID" value="XM_028673481.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733240"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00470700"/>
    <dbReference type="OrthoDB" id="29024at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000445">
        <property type="term" value="C:THO complex part of transcription export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040007">
        <property type="entry name" value="Tho2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021418">
        <property type="entry name" value="THO_THOC2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21597:SF0">
        <property type="entry name" value="THO COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21597">
        <property type="entry name" value="THO2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11262">
        <property type="entry name" value="Tho2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THO complex subunitTHOC2 C-terminal" evidence="3">
        <location>
            <begin position="2353"/>
            <end position="2648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="810"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1886"/>
            <end position="1950"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2282"/>
            <end position="2310"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="293"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2282"/>
            <end position="2301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2871" mass="338928" checksum="8A4FF7FFD2023FC9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY24</accession>
    <name>A0A1J1GY24_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fork head domain protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00503900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530267.1">
        <property type="nucleotide sequence ID" value="XM_028673856.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY24"/>
    <dbReference type="GeneID" id="39733572"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00503900"/>
    <dbReference type="OMA" id="YINNCEH"/>
    <dbReference type="OrthoDB" id="444265at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050923">
        <property type="entry name" value="Cell_Proc_Reg/RNA_Proc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23308">
        <property type="entry name" value="NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="645"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="421"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="471"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="528"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="556"/>
            <end position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="732" mass="89098" checksum="9ED85025810056D6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY54</accession>
    <name>A0A1J1GY54_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA pseudouridine(55) synthase</fullName>
            <ecNumber evidence="2">5.4.99.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00477100</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pseudouridine synthase TruB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.25" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529995.1">
        <property type="nucleotide sequence ID" value="XM_028673554.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY54"/>
    <dbReference type="GeneID" id="39733304"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00477100"/>
    <dbReference type="OrthoDB" id="9995526at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160148">
        <property type="term" value="F:tRNA pseudouridine(55) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990481">
        <property type="term" value="P:mRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01080">
        <property type="entry name" value="TruB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014780">
        <property type="entry name" value="tRNA_psdUridine_synth_TruB"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00431">
        <property type="entry name" value="TruB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13767:SF2">
        <property type="entry name" value="PSEUDOURIDYLATE SYNTHASE TRUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13767">
        <property type="entry name" value="TRNA-PSEUDOURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="domain" description="Pseudouridine synthase II N-terminal" evidence="8">
        <location>
            <begin position="378"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="187"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="141"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="187"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="237"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="258"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG97192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="570" mass="68027" checksum="DFB9F948DFE5FEAB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYH6</accession>
    <name>A0A1J1GYH6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mitochondrial ATP synthase F1, epsilon subunit, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00520200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ATPase epsilon family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530427.1">
        <property type="nucleotide sequence ID" value="XM_028674034.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYH6"/>
    <dbReference type="GeneID" id="39733735"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00520200"/>
    <dbReference type="OMA" id="YTNEMAV"/>
    <dbReference type="OrthoDB" id="269124at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042776">
        <property type="term" value="P:proton motive force-driven mitochondrial ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12153">
        <property type="entry name" value="F1-ATPase_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1620.20">
        <property type="entry name" value="ATP synthase, F1 complex, epsilon subunit superfamily, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006721">
        <property type="entry name" value="ATP_synth_F1_esu_mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036742">
        <property type="entry name" value="ATP_synth_F1_esu_sf_mt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12448">
        <property type="entry name" value="ATP SYNTHASE EPSILON CHAIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12448:SF0">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT EPSILON, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04627">
        <property type="entry name" value="ATP-synt_Eps"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48690">
        <property type="entry name" value="Epsilon subunit of mitochondrial F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="71" mass="8430" checksum="D7A925AC34720290" modified="2017-02-15" version="1">MWKAANVSYTRYASEMAEILRKCLKDPYSDIALERSKMHLKETIYKDGKPISQELHEEFQKAFKNLYGKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYI1</accession>
    <name>A0A1J1GYI1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosome production factor 2 homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Ribosome biogenesis protein RPF2 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00487600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Nucleus</location>
            <location evidence="1 4">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the RPF2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530099.1">
        <property type="nucleotide sequence ID" value="XM_028673670.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYI1"/>
    <dbReference type="GeneID" id="39733409"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00487600"/>
    <dbReference type="OMA" id="VGLKPMF"/>
    <dbReference type="OrthoDB" id="407658at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007109">
        <property type="entry name" value="Brix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039770">
        <property type="entry name" value="Rpf2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12728">
        <property type="entry name" value="BRIX DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12728:SF0">
        <property type="entry name" value="RIBOSOME PRODUCTION FACTOR 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04427">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00879">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50833">
        <property type="entry name" value="BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Brix" evidence="5">
        <location>
            <begin position="38"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="317" mass="37777" checksum="59DA97E66805BF05" modified="2017-02-15" version="1">MENENKEEIIDEIQAKAKTRKGNVILKKREGELNEDSKYCLFISGNKRTELLKNFMQDIYSLHKPLTCYMPKLHQNLSNVLDKIDKLVELCVHNNCSFFFLIFSTKKKPSRFLLGRLYNNKILDYYIFSLLSFIPIHIFPLSKEILYDTKPIVLIQGSYFEKNETTKYLKNVLFDFFKHKNIESFSKNSIQRLIVITAYESKKNINNSNKNNNENKYILSFRQYLLKKEFFDLKEKYTLNEIGPQFEFILENCKIPDFNIFQEALKKPQIPKKRKSDKIKVDEFGNNIKKVYIQKQNFSKLHTKHTKVLKKGNYNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYK0</accession>
    <name>A0A1J1GYK0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fam-i protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00376400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000097">
        <property type="protein sequence ID" value="CRG97391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530193.1">
        <property type="nucleotide sequence ID" value="XM_028673774.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYK0"/>
    <dbReference type="GeneID" id="39732294"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00376400"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="75"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="323"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="383" mass="47018" checksum="D9920C40E5892C80" modified="2017-02-15" version="1">MDLRLSDATSIDSSHNINEGNSTVGFAHRAIEGATVSIPENPLYDDLDLRDAIQNPSEDINLDSNSSMNLHHKKLLSIFQLVMIIISFLRFARTYSPKLRAKHKERVRLQNKWNNRDKKMNDDWEKMEEKWNERKQKENREKEELNKKKEERKKKTSYEMEQFNRKWDGENYSEEKSCKFLNYSCINGKCIKSLNEPSTRQAYNKTVKKKKKKKVLLDIIEEKLKGISFKKPLSELELEKMRREMLFRQVVELNEKWKKYEEHCIIMSQWEKNKRKKLEEKRRERRGKHENEMLKEKVEWEKSMREEKKEWENIMREKNKKWEKNMRKEKEKWEKSMRKKKKKWEKSMMEKNEMWKRDENIKVNEEESRLNLKWKKEFDKIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYV6</accession>
    <name>A0A1J1GYV6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phospholipase DDHD1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00521600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530441.1">
        <property type="nucleotide sequence ID" value="XM_028674049.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYV6"/>
    <dbReference type="GeneID" id="39733749"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00521600"/>
    <dbReference type="OMA" id="GFYKFIG"/>
    <dbReference type="OrthoDB" id="69269at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004620">
        <property type="term" value="F:phospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004177">
        <property type="entry name" value="DDHD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058055">
        <property type="entry name" value="PA-PLA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23509:SF10">
        <property type="entry name" value="LD21067P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23509">
        <property type="entry name" value="PA-PL1 PHOSPHOLIPASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02862">
        <property type="entry name" value="DDHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01127">
        <property type="entry name" value="DDHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51043">
        <property type="entry name" value="DDHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDHD" evidence="2">
        <location>
            <begin position="218"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="454"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="454"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="596" mass="70368" checksum="A1198E8D4B0F8D70" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ09</accession>
    <name>A0A1J1GZ09_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mediator of RNA polymerase II transcription subunit 18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00527800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530502.1">
        <property type="nucleotide sequence ID" value="XM_028674117.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ09"/>
    <dbReference type="GeneID" id="39733811"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00527800"/>
    <dbReference type="OMA" id="VNNKFKW"/>
    <dbReference type="OrthoDB" id="329332at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="278" mass="33270" checksum="2D284D78264BB234" modified="2017-02-15" version="1">MEENIEEIFNDFIGHLNGKTEEYTSEGKDINTIKTDEINFLDDNIFNTLGNNFFRYTEYSLSSLYICEENIPIEEDINFKTLLNIITKASDVNNKFKWVDYYFKYDSKEELNILSPKSQNKELLFREYLDPYHLKNVCLLRKFEQGAILKSSEKNKVDVKIVSEYNVHSSYKNVIRSFDYYLNHKIFTQADIFHNKYGNSDHIVILVLRHYKDENFQFPLFPDRVLVQIKSYSNDNKYSEMTQKNLLHYSEIFKPYISLRKVNYNLVEEIKNKITYTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ11</accession>
    <name>A0A1J1GZ11_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Trafficking protein particle complex subunit 13 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00023100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530597.1">
        <property type="nucleotide sequence ID" value="XM_028674223.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ11"/>
    <dbReference type="GeneID" id="39728754"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00023100"/>
    <dbReference type="OMA" id="HFFNKIT"/>
    <dbReference type="OrthoDB" id="10250284at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990072">
        <property type="term" value="C:TRAPPIII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010378">
        <property type="entry name" value="TRAPPC13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055427">
        <property type="entry name" value="TRAPPC13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13134">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13134:SF3">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06159">
        <property type="entry name" value="TRAPPC13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Trafficking protein particle complex subunit 13 N-terminal" evidence="1">
        <location>
            <begin position="13"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="380" mass="45083" checksum="4C2562810765DC59" modified="2017-02-15" version="1">MNEAKEGIKIELLRLCPPVLNYNIWNLFKIDNIINDNIEKNKNDDINISNEFSLSLLVNSKKIYFGQNFKSYINVSNNLKNNITLTLINVDIMMKHNTFNIYKNTGQINVLPNSFFDFITSFPVDFLDIFTIRCVVEYINGNDKKKLKKDFNFISKNPFSLKTNILHKKDNLYIEVVVKNIEEDNIMMNDLVIKDLKYELIKYEETLKVHNGIYYFKQNDEYSIIFCVKDEESKLSILNSLNDENIANIEILYFTRYGGKGVNNLHYLKKKMITDNIRIYLSKPKDIFYKVNKIYIFEIVFENNTDINILLEIFIHNNANIHVVNNFVKIHMIEKKKKISHFFNVLFINPGIHFFNKITIYNKTTKKKIDYIKLFKLFVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ31</accession>
    <name>A0A1J1GZ31_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00349300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529080.1">
        <property type="nucleotide sequence ID" value="XM_028672538.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ31"/>
    <dbReference type="GeneID" id="39732023"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00349300"/>
    <dbReference type="OMA" id="WVSEYLK"/>
    <dbReference type="OrthoDB" id="372232at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="264" mass="31811" checksum="42E566C0B520C073" modified="2017-02-15" version="1">MSYKMLSQIFILISFFFLTFFNIKCIKRTELKTHLYFKNYNLKKGNNKYNKFWFIGFHNKKYYLFNINKNRLILNKDIMKKNKPNFIYLQESEKQTNEFRNISSNEKDKHLLDKLVNKIINNKVTLAKYLLSGTFCIALFSLYKILLNKKIELTIRNIFKEKLLFINIPKRKHYFLSISLAEFRSSPLFFSTILIASYSLYIILKVYIEKYKEAKRIKSAIDAYNKNKNEYINTGIDSTNENDITDYFDKLEENNDFNKQEDIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ35</accession>
    <name>A0A1J1GZ35_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Subtilisin-like protease 1</fullName>
            <ecNumber evidence="14">3.4.21.62</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="primary">SUB1</name>
        <name evidence="21" type="ORF">PGAL8A_00028600</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>Hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyzes peptide amides.</text>
            <dbReference type="EC" id="3.4.21.62"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="15">Parasitophorous vacuole lumen</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 17 18">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.62" evidence="14"/>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530651.1">
        <property type="nucleotide sequence ID" value="XM_028674282.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ35"/>
    <dbReference type="GeneID" id="39728809"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00028600"/>
    <dbReference type="OMA" id="YRNLQWG"/>
    <dbReference type="OrthoDB" id="531541at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050131">
        <property type="entry name" value="Peptidase_S8_subtilisin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041089">
        <property type="entry name" value="SUB1_ProdP9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806:SF11">
        <property type="entry name" value="CEREVISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43806">
        <property type="entry name" value="PEPTIDASE S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18213">
        <property type="entry name" value="SUB1_ProdP9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0106">Calcium</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 17 18" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 17 18" id="KW-0645">Protease</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="8 17 18" id="KW-0720">Serine protease</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="10" id="KW-0865">Zymogen</keyword>
    <feature type="domain" description="SUB1 protease prodomain ProdP9" evidence="20">
        <location>
            <begin position="117"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="19">
        <location>
            <begin position="283"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="17">
        <location>
            <position position="289"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="17">
        <location>
            <position position="345"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="17">
        <location>
            <position position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00060500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00073004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF18213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="CRG97851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="605" mass="68753" checksum="8E5B6D75E3BD9ACA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ61</accession>
    <name>A0A1J1GZ61_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Kelch protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00352500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529112.1">
        <property type="nucleotide sequence ID" value="XM_028672573.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ61"/>
    <dbReference type="GeneID" id="39732055"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00352500"/>
    <dbReference type="OMA" id="EIMHNER"/>
    <dbReference type="OrthoDB" id="45365at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="408"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="17"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="59"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="509" mass="58656" checksum="FA76DE762693F3F4" modified="2017-02-15" version="1">MESNNLSEKITDEEEQNTQNENNENNEINEIDEKCNLKMDEPVETQKSENNEEIINEDSEPKKNKMDIKNNENGEVSKGFLSPPAFHLTEIMHNGNCFKKTQGHVAVELNGDICIYGGIVENKCTNNFIRYVPGINLFEKVRLNSNDIQPRAFCSGNVINEDNKKSIILFGGINEKNEIINETCKFDFQTKKWLIIHNKVNPCPRYKHASFSFENSIYIHGGLDKNDHVLSDLWCFSENMWKEVKQIRVTPEARHGHSLVFSLYGNARLAFLFGGNKKGFNGALSDTWIFNINTNRWKEISKSSGCKPCARWGHSAQLFDNEWMIIYGGITNGWIDNYALSDMYALNIYTFSWFEIDISTSKSFNRGYYGSLCFLPYKKSLHIFGGTDNSQEYSDAFSMSPLVTYVSYKTLTGKIEQLNDKMRNLSSNSNDSENIDLSEFDMKISELKEEVNNINEMMKTFETKFYELEKLNEQCEKILSKDIGSEAMEKLEERIRKLELSNNSIDKDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZD9</accession>
    <name>A0A1J1GZD9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH OST-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00037100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530733.1">
        <property type="nucleotide sequence ID" value="XM_028674373.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728895"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00037100"/>
    <dbReference type="OrthoDB" id="384400at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.610">
        <property type="entry name" value="LOTUS domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041966">
        <property type="entry name" value="LOTUS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025605">
        <property type="entry name" value="OST-HTH/LOTUS_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12872">
        <property type="entry name" value="OST-HTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69349">
        <property type="entry name" value="Phage fibre proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH OST-type" evidence="2">
        <location>
            <begin position="202"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="61"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1358" mass="158972" checksum="89C72C1E5E0AF735" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZF7</accession>
    <name>A0A1J1GZF7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00038700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530749.1">
        <property type="nucleotide sequence ID" value="XM_028674391.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZF7"/>
    <dbReference type="GeneID" id="39728911"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00038700"/>
    <dbReference type="OMA" id="NENICED"/>
    <dbReference type="OrthoDB" id="384658at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33621">
        <property type="entry name" value="ASPARTIC/GLUTAMIC ACID-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33621:SF2">
        <property type="entry name" value="RIBOSOMAL L1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101898">
        <property type="entry name" value="NHL repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="533"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="830" mass="99143" checksum="0220CCADD01FA141" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZL5</accession>
    <name>A0A1J1GZL5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00044700</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPL family. K-HECT subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530813.1">
        <property type="nucleotide sequence ID" value="XM_028674463.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728972"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00044700"/>
    <dbReference type="OMA" id="ACAIDVK"/>
    <dbReference type="OrthoDB" id="409931at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2410.10:FF:000007">
        <property type="entry name" value="Putative E3 ubiquitin-protein ligase HECTD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045322">
        <property type="entry name" value="HECTD1/TRIP12-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45670:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HECTD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45670">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE TRIP12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="770"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="898"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="domain" description="HECT" evidence="10">
        <location>
            <begin position="3085"/>
            <end position="3358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="123"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="483"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1366"/>
            <end position="1426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="2535"/>
            <end position="2614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="2634"/>
            <end position="2872"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="3030"/>
            <end position="3070"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1571"/>
            <end position="1598"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="2891"/>
            <end position="2954"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="145"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="491"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="509"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="539"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="553"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1372"/>
            <end position="1426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="2544"/>
            <end position="2559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="2598"/>
            <end position="2612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="2650"/>
            <end position="2699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="2700"/>
            <end position="2810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="2826"/>
            <end position="2838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="3030"/>
            <end position="3066"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="6">
        <location>
            <position position="3325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG98016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3358" mass="399909" checksum="F8AF2C703CF9890A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZV6</accession>
    <name>A0A1J1GZV6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Transcription factor with AP2 domain(S), putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ApiAP2</name>
        <name evidence="10" type="ORF">PGAL8A_00054700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530909.1">
        <property type="nucleotide sequence ID" value="XM_028674570.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729072"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00054700"/>
    <dbReference type="OrthoDB" id="387736at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2050">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028078">
        <property type="entry name" value="ACDC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14733">
        <property type="entry name" value="ACDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00847">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="8">
        <location>
            <begin position="1150"/>
            <end position="1202"/>
        </location>
    </feature>
    <feature type="domain" description="AP2-coincident C-terminal" evidence="9">
        <location>
            <begin position="3766"/>
            <end position="3879"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="131"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="450"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1217"/>
            <end position="1246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2611"/>
            <end position="2813"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="911"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1764"/>
            <end position="1851"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="2259"/>
            <end position="2286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="136"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="450"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1234"/>
            <end position="1246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="2611"/>
            <end position="2757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="2758"/>
            <end position="2768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="2778"/>
            <end position="2789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="2795"/>
            <end position="2813"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF14733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG98112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3887" mass="460156" checksum="B00740D8CEB8DFC3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H038</accession>
    <name>A0A1J1H038_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fam-b protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00062300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530981.1">
        <property type="nucleotide sequence ID" value="XM_028674650.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H038"/>
    <dbReference type="GeneID" id="39729148"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00062300"/>
    <dbReference type="OrthoDB" id="392573at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013244171" description="Fam-b protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="129" mass="15146" checksum="37893EEED49FE8C4" modified="2017-02-15" version="1">MRTVKIFLLICIIINNIIKCEINSFENVKEITKSIDENIMNVLDSVSVSHSIKTEKNILNDLSNYMQFLKELSLLDIEDMEYEGFLNIDKTDKKRYNKNITLKYSSRNGYKNNINDVKKEVNKSLFLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H079</accession>
    <name>A0A1J1H079_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Heat shock protein 70, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00053400</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000142">
        <property type="protein sequence ID" value="CRG98100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530897.1">
        <property type="nucleotide sequence ID" value="XM_028674557.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H079"/>
    <dbReference type="GeneID" id="39729059"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00053400"/>
    <dbReference type="OMA" id="QCPVIGI"/>
    <dbReference type="OrthoDB" id="2401965at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10241">
        <property type="entry name" value="ASKHA_NBD_HSP70_BiP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000153">
        <property type="entry name" value="Endoplasmic reticulum chaperone BiP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.34.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000172">
        <property type="entry name" value="Heat shock 70 kDa protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000026">
        <property type="entry name" value="Heat shock protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042050">
        <property type="entry name" value="BIP_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001413">
        <property type="entry name" value="PRK00290.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="607"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="618"/>
            <end position="628"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG98100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="628" mass="69849" checksum="618FFBD5265B9466" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0B0</accession>
    <name>A0A1J1H0B0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00056700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530929.1">
        <property type="nucleotide sequence ID" value="XM_028674592.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0B0"/>
    <dbReference type="GeneID" id="39729092"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00056700"/>
    <dbReference type="OrthoDB" id="361409at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="195"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="59"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="220"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="500" mass="59582" checksum="08A9802AD0354C17" modified="2017-02-15" version="1">MKELIGRSRNERKLDGIYNKQRDILVNRIKNKKNNDIYLNLSKRKTNEPLPFPEIYEKKRKVNKQNENEEKNVSQLNNKVSENNTTVYKGIYMILSKHIYSKNKFFKSVSIFTNLCINYMNNDNKTIFFYAFDHILNVFLEKYLYDDIKKNNIYTFYNYDELHIKCVISFFDKVINKIIDNRFIINNKNQENASSKEEGESITVNEKSDQKDLQENQVSSNTNNNDNILNENLKNNNLPNLSEPKNNLTKINELSYKLKDKVEQKVDIIKITKEEKKFLKLLKIKIYYLIILFKLNDNFVFNKLINIYRQIFEEIQNEFYIYEEKINEEKSKKVSDDTQLINENNVKDEENNNKLTQEKNVECNNDKLNDEEIINDYLSYFKGKWKLPSDYEIFKIKRNAFVKCLSNLFHFINIAWAKTSVESLFQDVYLKKKCFDICDEIIIENLQSSIKANINKRKSKYDSPHLLSIGESLNPVIDARDEKIISIHGSHIWSNKQMER</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0F5</accession>
    <name>A0A1J1H0F5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00061700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530977.1">
        <property type="nucleotide sequence ID" value="XM_028674646.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0F5"/>
    <dbReference type="GeneID" id="39729142"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00061700"/>
    <dbReference type="OrthoDB" id="375881at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG98180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="198" mass="23329" checksum="67B193CF6C086473" modified="2017-02-15" version="1">MNELNENKKNEEINETIELNINNIANKLANILYITSVSMKENFQLRNNLHYAKFINDMKSYCVNLIQSINNLNSNFHNLTCLPVHSIPRNPYNNIQDPNTITSNISVDDLTDKIKENKKLMNSFNSKYKKINFNVLKPIENFNDYVKSALNNIEHIKMPFKYEEKKTYGNVLSERLKDKQKDFEHLELYIAKINYGIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0L6</accession>
    <name>A0A1J1H0L6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00054200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530904.1">
        <property type="nucleotide sequence ID" value="XM_028674564.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0L6"/>
    <dbReference type="GeneID" id="39729067"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00054200"/>
    <dbReference type="OMA" id="NCNNSEL"/>
    <dbReference type="OrthoDB" id="372065at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="545"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="486"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="554"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="572" mass="68137" checksum="99C6C00C96809A4F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0Q6</accession>
    <name>A0A1J1H0Q6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00058200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530944.1">
        <property type="nucleotide sequence ID" value="XM_028674608.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0Q6"/>
    <dbReference type="GeneID" id="39729107"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00058200"/>
    <dbReference type="OMA" id="CFFENIS"/>
    <dbReference type="OrthoDB" id="370306at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="697"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="139"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="276"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="952"/>
            <end position="979"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG98147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1079" mass="129288" checksum="69A08EAEF15238C6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1B6</accession>
    <name>A0A1J1H1B6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">General stress protein FMN-binding split barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00467400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529896.1">
        <property type="nucleotide sequence ID" value="XM_028673445.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1B6"/>
    <dbReference type="GeneID" id="39733207"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00467400"/>
    <dbReference type="OMA" id="QHWKSNI"/>
    <dbReference type="OrthoDB" id="370041at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038725">
        <property type="entry name" value="YdaG_split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16242">
        <property type="entry name" value="Pyrid_ox_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="General stress protein FMN-binding split barrel" evidence="3">
        <location>
            <begin position="250"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="65"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="361" mass="42974" checksum="C2E932693AC6A240" modified="2017-02-15" version="1">MNNLYKRFFFHSKILNKYILYEGNAITKHNYIYMKRRGFFFKTQKNNIIKNEIEEILKNENAVSMEEMKKSLNIKDDEEEEKKKKYEEERKKKFIHKKGKFKRLIIFIGFQSVPIICLMYLFKYLEDAKLSELNYSFNSSEDIINETLKLIEGSSKCFCLYFNNNQINTFYIEPLNPEESEVNYGNELEHENNYSNKGNQNNIINVHEKEKRALNEKNEENIKDFLYSLNKPLMQKVMRSKSSVGLPLNYLYFSTSKNSDIHNFLKTKKSDITLLYSDDKKNVYATLYGNASIIESEEIKNVVWNDKWSYIISDNYKENYILIKFTPSTVSLKTIGLKDDHWKNNIVKKSIINDNISWVKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1H4</accession>
    <name>A0A1J1H1H4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Secreted ookinete protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">PSOP24</name>
        <name evidence="5" type="ORF">PGAL8A_00376000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000086">
        <property type="protein sequence ID" value="CRG97157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529960.1">
        <property type="nucleotide sequence ID" value="XM_028673515.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1H4"/>
    <dbReference type="GeneID" id="39732290"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00376000"/>
    <dbReference type="OMA" id="QHNEFPE"/>
    <dbReference type="OrthoDB" id="372659at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012701225" evidence="4">
        <location>
            <begin position="20"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="310"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="369"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="40"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="197"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="54"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="895" mass="105848" checksum="257E9721D746ADBB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1T6</accession>
    <name>A0A1J1H1T6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peroxiredoxin, putative</fullName>
            <ecNumber evidence="8">1.11.1.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">nPrx</name>
        <name evidence="8" type="ORF">PGAL8A_00486500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.15" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530088.1">
        <property type="nucleotide sequence ID" value="XM_028673658.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1T6"/>
    <dbReference type="GeneID" id="39733398"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00486500"/>
    <dbReference type="OMA" id="SHRKFAT"/>
    <dbReference type="OrthoDB" id="338622at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03017">
        <property type="entry name" value="PRX_BCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050924">
        <property type="entry name" value="Peroxiredoxin_BCP/PrxQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42801:SF23">
        <property type="entry name" value="PEROXIREDOXIN DOT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42801">
        <property type="entry name" value="THIOREDOXIN-DEPENDENT PEROXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1 8" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="5" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant" evidence="7">
        <location>
            <begin position="20"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="157"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="196"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="206"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="243"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="258"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="321"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="350"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="359" mass="41982" checksum="DFEA05BF3A185539" modified="2017-02-15" version="1">MDQIKENKTIADSILKIDLLNEKNEKTNLYNEIKKNKDKNGMVIFIYPKANTPGCTKQAQLFKENFEKIVKNKYYVYGLSADSPKAQSKWKQKLNLQYDLLCDEEKKLLKEFGCLKGNSIIRSHLILRNDFNLSYFKKGVSPTSSADDTLNFLLKGEENGNTYSNENGEKKKSLPKINENEKEKNKKSVKVKKNKNGINKAANIGKKNEIKKNKNSLKELNNKEEHKKELKKKGKNKGENKGEKKKVKNKEVKKKLNTKMEDKNKKINRQEKKNFKIKNESKKQMNSKDESKKKIKNKEQKKELNIKGENKKELKKKVEKKKMEKKKDEIKKNSKIKDSNKNKSEIKNEKKVKKVLKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H287</accession>
    <name>A0A1J1H287_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Transcription elongation factor s-II, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00519200</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530420.1">
        <property type="nucleotide sequence ID" value="XM_028674026.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H287"/>
    <dbReference type="GeneID" id="39733725"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00519200"/>
    <dbReference type="OMA" id="DACDPFR"/>
    <dbReference type="OrthoDB" id="44867at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13749">
        <property type="entry name" value="Zn-ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.10">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.30">
        <property type="entry name" value="Transcription elongation factor S-II, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035100">
        <property type="entry name" value="TF_IIS-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003617">
        <property type="entry name" value="TFIIS/CRSP70_N_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035441">
        <property type="entry name" value="TFIIS/LEDGF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003618">
        <property type="entry name" value="TFIIS_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036575">
        <property type="entry name" value="TFIIS_cen_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017923">
        <property type="entry name" value="TFIIS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001222">
        <property type="entry name" value="Znf_TFIIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11477:SF0">
        <property type="entry name" value="IP08861P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11477">
        <property type="entry name" value="TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08711">
        <property type="entry name" value="Med26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07500">
        <property type="entry name" value="TFIIS_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01096">
        <property type="entry name" value="Zn_ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006704">
        <property type="entry name" value="TF_IIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00510">
        <property type="entry name" value="TFS2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00509">
        <property type="entry name" value="TFS2N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00440">
        <property type="entry name" value="ZnF_C2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47676">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46942">
        <property type="entry name" value="Elongation factor TFIIS domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51321">
        <property type="entry name" value="TFIIS_CENTRAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51319">
        <property type="entry name" value="TFIIS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00466">
        <property type="entry name" value="ZF_TFIIS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51133">
        <property type="entry name" value="ZF_TFIIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="12" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIS N-terminal" evidence="10">
        <location>
            <begin position="11"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="TFIIS central" evidence="11">
        <location>
            <begin position="212"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="TFIIS-type" evidence="9">
        <location>
            <begin position="344"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="115"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="115"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="132"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="171"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG97619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="385" mass="45437" checksum="62FE0B9F02370D9F" modified="2017-02-15" version="1">MNELENITYIKNIQERLKDKEDKLADASSENIDSILIKEINEDLNLLKNVKINKNILKSTKIGITVNKFTKINNEEIQNLAKELVEKWKNIALNEKISNIKNIENIKKRKSEIVESGDTRSDEYESKKIKAQNDSNKNYSLDNSENNDKEEQNNCYENNVEKQNDDTNGINTDGKNNNSNFNNDKNIKDHKITDLKTLNEWNYEGKLHNDVHRDKAKQFLFKAFLIGSSDNLLYIIDRKKLNEIIYDIENELQKYYIQKRNSQREYNMQLKSIKFNLSDKKNPNFNEKIYKEIISPKELVTMNSQDMASDEKKNEREKCLQESLIACQSDWDVKNILLKKSRKGEFQCYKCKGYDTIYHQLQTRSSDEPMTTFVTCLKCNNRWKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H391</accession>
    <name>A0A1J1H391_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein bL28c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00024200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530607.1">
        <property type="nucleotide sequence ID" value="XM_028674234.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H391"/>
    <dbReference type="GeneID" id="39728765"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00024200"/>
    <dbReference type="OMA" id="VRFKNNN"/>
    <dbReference type="OrthoDB" id="361870at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.40">
        <property type="entry name" value="Ribosomal protein L28/L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026569">
        <property type="entry name" value="Ribosomal_bL28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="Ribosomal_bL28/bL31-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001383">
        <property type="entry name" value="Ribosomal_bL28_bact-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037147">
        <property type="entry name" value="Ribosomal_bL28_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00009">
        <property type="entry name" value="L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13528">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L28, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13528:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL28M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00830">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="L28p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="250" mass="29871" checksum="1A1E94CA0EA870BB" modified="2017-02-15" version="1">MQSKTTNKIFNLTKNVYILYIIININSLLLYGHSTINKYETKRINFQNYFYVKLLIKKQQICKNNYSYKKPHVSKFSLYTKKRHKEALEIKKYRMKGTSSIARHYGLKGKKRINKVTMMPHKEIKLPIRRCMILGKMDNWNARKISKSGVKTHRIQRLNLIKKRIFFEEENRFVKLKVSAKGLKTIKKYGLSYCCKKFNLDLSKKKFDAGYSLRRKKKKDIINENHKLNEKTNEIHEDANNIMNNLNLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3N5</accession>
    <name>A0A1J1H3N5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Adrenodoxin-type ferredoxin, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00053000</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the adrenodoxin/putidaredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000134">
        <property type="protein sequence ID" value="CRG98095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530892.1">
        <property type="nucleotide sequence ID" value="XM_028674551.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3N5"/>
    <dbReference type="GeneID" id="39729055"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00053000"/>
    <dbReference type="OMA" id="TCHVIFM"/>
    <dbReference type="OrthoDB" id="268593at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140647">
        <property type="term" value="P:P450-containing electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001055">
        <property type="entry name" value="Adrenodoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23426:SF72">
        <property type="entry name" value="2FE-2S FERREDOXIN-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23426">
        <property type="entry name" value="FERREDOXIN/ADRENODOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00355">
        <property type="entry name" value="ADRENODOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="9">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG98095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="92" mass="10441" checksum="67088CEBF0EB4FDA" modified="2017-02-15" version="1">MENKIFTHIFNSACEGFCACSTCHVIIDEKFYDLLPEASDNEIDMLELAPCITETSRLGCQVKLKKELNGIKIKLPPMTRNFYVDGYVPTPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H465</accession>
    <name>A0A1J1H465_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein phosphatase 1 regulatory subunit 21 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00057300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530935.1">
        <property type="nucleotide sequence ID" value="XM_028674598.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H465"/>
    <dbReference type="GeneID" id="39729098"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00057300"/>
    <dbReference type="OrthoDB" id="392668at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019343">
        <property type="entry name" value="PPP1R21_N"/>
    </dbReference>
    <dbReference type="SMART" id="SM01254">
        <property type="entry name" value="KLRAQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein phosphatase 1 regulatory subunit 21 N-terminal" evidence="2">
        <location>
            <begin position="7"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="7"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="110"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="742"/>
            <end position="801"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="840" mass="100833" checksum="75668E0CAAB85C1E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H4I1</accession>
    <name>A0A1J1H4I1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerase</fullName>
            <ecNumber evidence="2">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_API04000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <geneLocation type="apicoplast" evidence="8"/>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="2"/>
    <dbReference type="EMBL" id="LN835293">
        <property type="protein sequence ID" value="CRG98250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009325477.1">
        <property type="nucleotide sequence ID" value="NC_031963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H4I1"/>
    <dbReference type="GeneID" id="30315809"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_API04100"/>
    <dbReference type="OMA" id="DNIFETK"/>
    <dbReference type="OrthoDB" id="392892at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Apicoplast API"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1790.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376:SF54">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0933">Apicoplast</keyword>
    <keyword evidence="3" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-0934">Plastid</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG98250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="444" mass="54776" checksum="D52F9E51943E2C69" modified="2017-02-15" version="1">MYNNINNILNLNILEKNYLNYMYYYKYYNIKYYKYNNNLYYIFLDKFYNNIIILKKIKKLYLINVNKLLFFIKKKKFLFLYEIIKYNWYKYLLLNNNYNLFIICNNYIKYLYKYNIKLNLYIIKNLYNINNNLIHNNIIYKNNYNIYNNQVNYYQYKYFNLFINNNFYNKIYYNYNNNNIFNIYLSDITIGLQSINIIFENKNIINNISFISNNIFVIFYIRYYNYLNNIIYIYNICNKYKIKYFSYKLNFYSYIFEDISSIIYSGYSLNTDFYCINKNLKYYFNYLLKNINIYQSAKSSFIYIYNILLESIIKQYSYQNIYLPSIYFELVIKKMLSCIKIISNNFKIFKYNDIIPLYLINIINYSLNLNNIYIYKYEPIILGITKSILANSGFLTNISFQNTFKIINLNILNNKIDWLIDIKSKIIMTDLLPVGNGWYRYLTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2012-07-11" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>I2FKC8</accession>
    <name>I2FKC8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial</fullName>
            <ecNumber evidence="10">6.2.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Succinyl-CoA synthetase beta chain</fullName>
            <shortName evidence="10">SCS-beta</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">LSC2</name>
        <name evidence="14" type="ORF">PGAL8A_00303200</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Gene" volume="502" first="36" last="39">
            <title>Age of the last common ancestor of extant Plasmodium parasite lineages.</title>
            <authorList>
                <person name="Hayakawa T."/>
                <person name="Tachibana S."/>
                <person name="Hikosaka K."/>
                <person name="Arisue N."/>
                <person name="Matsui A."/>
                <person name="Horii T."/>
                <person name="Tanabe K."/>
            </authorList>
            <dbReference type="PubMed" id="22555021"/>
            <dbReference type="DOI" id="10.1016/j.gene.2012.04.037"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>succinate + ATP + CoA = succinyl-CoA + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17661"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.2.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for GTP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the succinate/malate CoA ligase beta subunit family.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.5" evidence="10"/>
    <dbReference type="EMBL" id="AB571137">
        <property type="protein sequence ID" value="BAM15613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="I2FKC8"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00303200"/>
    <dbReference type="OMA" id="DIGCMIN"/>
    <dbReference type="OrthoDB" id="1552at2759"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00999"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042709">
        <property type="term" value="C:succinate-CoA ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006104">
        <property type="term" value="P:succinyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000002">
        <property type="entry name" value="Succinate--CoA ligase [ADP-forming] subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.261:FF:000001">
        <property type="entry name" value="Succinate--CoA ligase [ADP-forming] subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.20:FF:000004">
        <property type="entry name" value="Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00558">
        <property type="entry name" value="Succ_CoA_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013650">
        <property type="entry name" value="ATP-grasp_succ-CoA_synth-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="SUCC_ACL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005809">
        <property type="entry name" value="Succ_CoA_ligase-like_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001913">
        <property type="entry name" value="PRK00696.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01016">
        <property type="entry name" value="sucCoAbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11815:SF1">
        <property type="entry name" value="SUCCINATE--COA LIGASE [ADP-FORMING] SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11815">
        <property type="entry name" value="SUCCINYL-COA SYNTHETASE BETA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08442">
        <property type="entry name" value="ATP-grasp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001554">
        <property type="entry name" value="SucCS_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="2 10" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="ATP-grasp" evidence="12">
        <location>
            <begin position="52"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="100"/>
            <end position="102"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="319"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit alpha</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="376"/>
            <end position="378"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit alpha</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00063570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="BAM15613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG95820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="456" mass="51160" checksum="D7B542C912AEAB7A" modified="2012-07-11" version="1">MLPLKNEFKFMMRLNRNIVSNIWNKKNKLHFGNKSRFFIEKKYLSIHEYLSIDLLRSHNIPCAQGFPAKTPEEAEEKALELQNICGDIDLVVKAQVLSGGRGVGYFKENNFEGGVHICRNSMEVKEVASKMLNNTLVTKQSGIEGKKCNTVFICERFYIRKERYVAFLLDRSSDGILLLGSSVGGSSIEDISKKNPDAIYKMNIDIKNGLSNGQSREFCEKIGFKNNELDIVSDIIVNLYKIFKKYDCTLLEINPLSETNDGRVLCCDAKLNFDDNAEFRQKEIFEKRDISQENAEEMEAKKYNLNYVSLDGNIACMVNGAGLAMATLDLIVLHNGSPSNFLDVGGGATEKEISEALKIINNNNKAKVCFINILGGIMRCDIIAKGLINATKEVNFKKPLIIRLEGTNQEEAERLIKESNIKCILCQDMNAAAEKSVAMANIIEIAKKSNINIAFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL25</accession>
    <name>A0A1J1GL25_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">NEK4</name>
        <name evidence="13" type="ORF">PGAL8A_00082400</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 15">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 15">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525942.1">
        <property type="nucleotide sequence ID" value="XM_028670710.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL25"/>
    <dbReference type="GeneID" id="39729348"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00082400"/>
    <dbReference type="OMA" id="MINIVME"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08215">
        <property type="entry name" value="STKc_Nek"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NIMA related kinase 4"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Probable serine/threonine-protein kinase nek1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051131">
        <property type="entry name" value="NEK_Ser/Thr_kinase_NIMA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44899">
        <property type="entry name" value="CAMK FAMILY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44899:SF3">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE NEK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000654">
        <property type="entry name" value="Integrin-linked_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="4"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG93120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="310" mass="36416" checksum="65F86484F78C003C" modified="2017-02-15" version="1">MNKYEKIRDIGKGNYGNTVLVRDKKNDHYVMKIINISQMSQKEKKQCLKEVELLSKLNHPFIVKYIESYIEGDTLRIIMKHCKGGDLYHYIQNKKKQNTPIKEKRILIWLTQILTALKFLHSNHILHRDMKSLNILIDSDKRVRLCDFGISKVLENTLDYANTLIGTPYYLSPELCKDKKYSWPSDVWATGCLIYELATFRTPFHSTKGIQQLCYNIRYAPIPDLPHIYSKELNNIYKSMLVREPNYRATVQQLLVSDLVQRQLKLLIEEKIREKQTMKKPLKEKPTIENDNSGVNEQEVKTLLLDVIDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL31</accession>
    <name>A0A1J1GL31_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RAVE complex protein Rav1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00080600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525924.1">
        <property type="nucleotide sequence ID" value="XM_028670510.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729330"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00080600"/>
    <dbReference type="OrthoDB" id="342131at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043291">
        <property type="term" value="C:RAVE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007035">
        <property type="term" value="P:vacuolar acidification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052208">
        <property type="entry name" value="DmX-like/RAVE_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13950:SF9">
        <property type="entry name" value="RABCONNECTIN-3A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13950">
        <property type="entry name" value="RABCONNECTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="2314"/>
            <end position="2336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="2410"/>
            <end position="2430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="2581"/>
            <end position="2598"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="2605"/>
            <end position="2629"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="2641"/>
            <end position="2663"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="2729"/>
            <end position="2753"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="132"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="283"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1629"/>
            <end position="1655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1673"/>
            <end position="1719"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2167"/>
            <end position="2186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3961"/>
            <end position="4009"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="4105"/>
            <end position="4127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="4144"/>
            <end position="4203"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2665"/>
            <end position="2695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="136"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="162"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="285"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1677"/>
            <end position="1695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1702"/>
            <end position="1717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2172"/>
            <end position="2181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="3961"/>
            <end position="3973"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="3974"/>
            <end position="3999"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="4105"/>
            <end position="4123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="4145"/>
            <end position="4192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="4665" mass="562931" checksum="0267CD87B30BC334" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLE6</accession>
    <name>A0A1J1GLE6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphatidylinositol 4-kinase, putative</fullName>
            <ecNumber evidence="6">2.7.1.67</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00093400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.67" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526052.1">
        <property type="nucleotide sequence ID" value="XM_028671932.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729458"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00093400"/>
    <dbReference type="OMA" id="ASINDYC"/>
    <dbReference type="OrthoDB" id="10264149at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004430">
        <property type="term" value="F:1-phosphatidylinositol 4-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015433">
        <property type="entry name" value="PI3/4_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048:SF22">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="221"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="442"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="481"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1038"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1214"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1241"/>
            <end position="1262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1476"/>
            <end position="1495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1501"/>
            <end position="1521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1820"/>
            <end position="1837"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1849"/>
            <end position="1872"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1911"/>
            <end position="1928"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="2114"/>
            <end position="2131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="2164"/>
            <end position="2186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="2411"/>
            <end position="2432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="2463"/>
            <end position="2482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="2858"/>
            <end position="2876"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="2921"/>
            <end position="2942"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="5">
        <location>
            <begin position="3981"/>
            <end position="4375"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="3356"/>
            <end position="3383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="4390" mass="534673" checksum="E94B9B622648E565" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLE8</accession>
    <name>A0A1J1GLE8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RAP protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00073300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525851.1">
        <property type="nucleotide sequence ID" value="XM_028674945.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLE8"/>
    <dbReference type="GeneID" id="39729258"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00073300"/>
    <dbReference type="OrthoDB" id="377680at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013584">
        <property type="entry name" value="RAP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08373">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00952">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51286">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="412"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="RAP" evidence="2">
        <location>
            <begin position="577"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="651" mass="79374" checksum="599BF46154F845E5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLH9</accession>
    <name>A0A1J1GLH9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Anaphase-promoting complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00096800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526084.1">
        <property type="nucleotide sequence ID" value="XM_028672288.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729492"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00096800"/>
    <dbReference type="OrthoDB" id="296935at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007091">
        <property type="term" value="P:metaphase/anaphase transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070979">
        <property type="term" value="P:protein K11-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024990">
        <property type="entry name" value="Apc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12827:SF3">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12827">
        <property type="entry name" value="MEIOTIC CHECKPOINT REGULATOR TSG24 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0498">Mitosis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1024"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1267"/>
            <end position="1291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1908"/>
            <end position="1960"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1986"/>
            <end position="2023"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2203"/>
            <end position="2235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2257"/>
            <end position="2284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2716"/>
            <end position="2789"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="3129"/>
            <end position="3148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1908"/>
            <end position="1936"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1986"/>
            <end position="2008"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="2716"/>
            <end position="2747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="2764"/>
            <end position="2788"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="4492" mass="540323" checksum="1DCD9728F3BD6365" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLK4</accession>
    <name>A0A1J1GLK4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mitogen-activated protein kinase organizer 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MORG1</name>
        <name evidence="7" type="ORF">PGAL8A_00079500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the WD repeat MORG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525915.1">
        <property type="nucleotide sequence ID" value="XM_028670410.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLK4"/>
    <dbReference type="GeneID" id="39729320"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00079500"/>
    <dbReference type="OMA" id="GGKICCC"/>
    <dbReference type="OrthoDB" id="71437at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051980">
        <property type="entry name" value="WD_repeat_MORG1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22842:SF3">
        <property type="entry name" value="WD REPEAT DOMAIN-CONTAINING PROTEIN 83"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22842">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="13"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="56"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="364" mass="42853" checksum="BBC012FB89167F99" modified="2017-02-15" version="1">MNINLNAQTTGKLSGHKACITKILFSNDENYIVSSSLDNKICLWNINTQLHINTYKDVHKKGINDIALFRDNTKFFSAGNDMYAYLWDTLSNRILNRINVNDKINVIKLSKNEKLLFCSKNNAINIYDFKERDFKKKNNPLQIFNDAKDMISDIYIDDYEIYSCSIDNILRLYDLRMGKMTSYNMKSSILSIDVTKDRNYFCVNLIDNSIKLIEKNSGIVLALYKGDMNNNHKRNIKFDNKNKYIFSCSYKNELYIYDIVKSNLINNTTFYNDLEYEENLDIYKNTYFKINIGKPTYYLNINQNLLTENTYIDREKYDSVLNKYKIYGKKAKMHLSDNDFKNINNKLVCGDVDGDIHILQLYYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM07</accession>
    <name>A0A1J1GM07_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein tyrosine phosphatase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PTP2</name>
        <name evidence="3" type="ORF">PGAL8A_00109300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526210.1">
        <property type="nucleotide sequence ID" value="XM_028673688.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM07"/>
    <dbReference type="GeneID" id="39729619"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00109300"/>
    <dbReference type="OrthoDB" id="2017893at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14498">
        <property type="entry name" value="DSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46381:SF2">
        <property type="entry name" value="MAP KINASE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46381">
        <property type="entry name" value="MKPA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="1">
        <location>
            <begin position="829"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="2">
        <location>
            <begin position="896"/>
            <end position="952"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1149" mass="139067" checksum="8B69909ACA195BA8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM82</accession>
    <name>A0A1J1GM82_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00124100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526356.1">
        <property type="nucleotide sequence ID" value="XM_028674757.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM82"/>
    <dbReference type="GeneID" id="39729766"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00124100"/>
    <dbReference type="OrthoDB" id="375810at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="131" mass="15287" checksum="8AA65FF6FC1ABD1D" modified="2017-02-15" version="1">MINLATVILFSTYGRNLGNFFFNTCLFFANYLNFVCFILKKISHIFKINTYKDLNGLHNIKQANLNGLIKENKSMHLLNISCINDLDVLNSSILETETEINEHLSTEVEDFDEDEYNFEFIDLVQQNSFEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMG3</accession>
    <name>A0A1J1GMG3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">WD repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00125500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526370.1">
        <property type="nucleotide sequence ID" value="XM_028674772.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMG3"/>
    <dbReference type="GeneID" id="39729780"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00125500"/>
    <dbReference type="OMA" id="NPSHNCL"/>
    <dbReference type="OrthoDB" id="1935146at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034388">
        <property type="term" value="C:Pwp2p-containing subcomplex of 90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045161">
        <property type="entry name" value="Utp18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18359:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 18 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18359">
        <property type="entry name" value="WD-REPEAT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3" id="KW-0853">WD repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="541" mass="64281" checksum="EB77D8729D296E00" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMG5</accession>
    <name>A0A1J1GMG5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00130000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526415.1">
        <property type="nucleotide sequence ID" value="XM_028674822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMG5"/>
    <dbReference type="GeneID" id="39729825"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00130000"/>
    <dbReference type="OMA" id="RMRYFFN"/>
    <dbReference type="OrthoDB" id="370635at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="695"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="709"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="737"/>
            <end position="746"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="746" mass="89886" checksum="2019050F73972E14" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMI7</accession>
    <name>A0A1J1GMI7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Polyadenylate-binding protein</fullName>
            <shortName evidence="9">PABP</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">PABP</name>
        <name evidence="13" type="ORF">PGAL8A_00125400</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Binds the poly(A) tail of mRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the polyadenylate-binding protein type-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526369.1">
        <property type="nucleotide sequence ID" value="XM_028674771.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMI7"/>
    <dbReference type="GeneID" id="39729779"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00125400"/>
    <dbReference type="OMA" id="NATYSMA"/>
    <dbReference type="OrthoDB" id="19742at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12378">
        <property type="entry name" value="RRM1_I_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12379">
        <property type="entry name" value="RRM2_I_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12381">
        <property type="entry name" value="RRM4_I_PABPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000651">
        <property type="entry name" value="Poly(A) binding protein cytoplasmic 1 like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1900.10:FF:000004">
        <property type="entry name" value="Polyadenylate-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000003">
        <property type="entry name" value="Polyadenylate-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000385">
        <property type="entry name" value="Polyadenylate-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1900.10">
        <property type="entry name" value="c-terminal domain of poly(a) binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036053">
        <property type="entry name" value="PABP-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006515">
        <property type="entry name" value="PABP_1234"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002004">
        <property type="entry name" value="PABP_HYD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034364">
        <property type="entry name" value="PABP_RRM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045305">
        <property type="entry name" value="RRM2_I_PABPs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01628">
        <property type="entry name" value="PABP-1234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24012">
        <property type="entry name" value="RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00658">
        <property type="entry name" value="MLLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00517">
        <property type="entry name" value="PolyA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63570">
        <property type="entry name" value="PABC (PABP) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51309">
        <property type="entry name" value="PABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 8 9" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="11">
        <location>
            <begin position="16"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="11">
        <location>
            <begin position="104"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="11">
        <location>
            <begin position="193"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="11">
        <location>
            <begin position="374"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="PABC" evidence="12">
        <location>
            <begin position="714"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="251"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="563"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="643"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="255"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="276"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="326"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="563"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="647"/>
            <end position="678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG93547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="790" mass="89478" checksum="6C0B2AF7160151B8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMJ3</accession>
    <name>A0A1J1GMJ3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">G-protein associated signal transduction protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00135900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SYG1 (TC 2.A.94) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526476.1">
        <property type="nucleotide sequence ID" value="XM_028674891.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMJ3"/>
    <dbReference type="GeneID" id="39729884"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00135900"/>
    <dbReference type="OMA" id="FMQLYGV"/>
    <dbReference type="OrthoDB" id="9970435at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000822">
        <property type="term" value="F:inositol hexakisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016036">
        <property type="term" value="P:cellular response to phosphate starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004342">
        <property type="entry name" value="EXS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10783:SF103">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 53 MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10783">
        <property type="entry name" value="XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03124">
        <property type="entry name" value="EXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51380">
        <property type="entry name" value="EXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="279"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="317"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="352"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="479"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="508"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="552"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="582"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="8">
        <location>
            <begin position="1"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="EXS" evidence="7">
        <location>
            <begin position="439"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="633" mass="75846" checksum="B3EF17F750A0B3BA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMK2</accession>
    <name>A0A1J1GMK2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00127000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526385.1">
        <property type="nucleotide sequence ID" value="XM_028674789.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMK2"/>
    <dbReference type="GeneID" id="39729795"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00127000"/>
    <dbReference type="OMA" id="ECNEIMV"/>
    <dbReference type="OrthoDB" id="360766at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="527"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="571"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="529"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="586"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="661" mass="79198" checksum="F0D6C0860D21F3E9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMN5</accession>
    <name>A0A1J1GMN5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Multidrug resistance-associated protein 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">MRP2</name>
        <name evidence="12" type="ORF">PGAL8A_00130200</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526417.1">
        <property type="nucleotide sequence ID" value="XM_028674825.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729827"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00130200"/>
    <dbReference type="OMA" id="HINTDCE"/>
    <dbReference type="OrthoDB" id="4865934at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000067">
        <property type="entry name" value="Multidrug resistance protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF456">
        <property type="entry name" value="MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN LETHAL(2)03659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="125"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="450"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="487"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="561"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1291"/>
            <end position="1316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1351"/>
            <end position="1379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1385"/>
            <end position="1406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1427"/>
            <end position="1445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1451"/>
            <end position="1468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1529"/>
            <end position="1551"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1571"/>
            <end position="1592"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="442"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="761"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="1351"/>
            <end position="1547"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="1688"/>
            <end position="1948"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG93595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1949" mass="229502" checksum="09F75D2847E7475A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMP3</accession>
    <name>A0A1J1GMP3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nucleoside diphosphate kinase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00134100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the NDK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526458.1">
        <property type="nucleotide sequence ID" value="XM_028674870.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729866"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00134100"/>
    <dbReference type="OMA" id="IVCLIVE"/>
    <dbReference type="OrthoDB" id="270127at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003341">
        <property type="term" value="P:cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="entry name" value="Nucleoside diphosphate kinase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034907">
        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46161">
        <property type="entry name" value="NUCLEOSIDE DIPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46161:SF1">
        <property type="entry name" value="NUCLEOSIDE DIPHOSPHATE KINASE HOMOLOG 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="Nucleoside diphosphate kinase, NDK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51374">
        <property type="entry name" value="NDPK_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleoside diphosphate kinase-like" evidence="4">
        <location>
            <begin position="147"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1328"/>
            <end position="1351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1374"/>
            <end position="1417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1383"/>
            <end position="1417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1644" mass="197266" checksum="C8C8A9A0A56D2F24" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMY4</accession>
    <name>A0A1J1GMY4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Nuclear polyadenylated RNA-binding protein NAB2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">NAB2</name>
        <name evidence="11" type="ORF">PGAL8A_00151600</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ZC3H14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526628.1">
        <property type="nucleotide sequence ID" value="XM_028675059.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMY4"/>
    <dbReference type="GeneID" id="39730040"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00151600"/>
    <dbReference type="OMA" id="YYCNYSH"/>
    <dbReference type="OrthoDB" id="5589010at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008143">
        <property type="term" value="F:poly(A) binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043488">
        <property type="term" value="P:regulation of mRNA stability"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1390.10">
        <property type="entry name" value="PWI domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040366">
        <property type="entry name" value="Nab2/ZC3H14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14738">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14738:SF29">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14608">
        <property type="entry name" value="zf-CCCH_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 8" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="10">
        <location>
            <begin position="568"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="8">
        <location>
            <begin position="568"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="84"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="497"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="84"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="130"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="166"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="177"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="190"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="497"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="512"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="524"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG93807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="826" mass="96796" checksum="529901079EA980B8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN25</accession>
    <name>A0A1J1GN25_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00154300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526655.1">
        <property type="nucleotide sequence ID" value="XM_028675088.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN25"/>
    <dbReference type="GeneID" id="39730067"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00154300"/>
    <dbReference type="OMA" id="ECREEDF"/>
    <dbReference type="OrthoDB" id="392772at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="309"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="413"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="563" mass="67546" checksum="128CAAA3FB8E9DAA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNI2</accession>
    <name>A0A1J1GNI2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00154700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526659.1">
        <property type="nucleotide sequence ID" value="XM_028675093.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNI2"/>
    <dbReference type="GeneID" id="39730071"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00154700"/>
    <dbReference type="OMA" id="YIYEYTP"/>
    <dbReference type="OrthoDB" id="391656at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="378" mass="45881" checksum="B99F0BA6D842E2E7" modified="2017-02-15" version="1">MKKIKLNVTREEDNLQSNIYYVCEKNILISQLNLTINYDENHLTDEEVIEKDNSMYLNYDKNKANEEKKKNINIKISYSDELNNLYFNNVLNNIYDYIFEYKTNNLNINKNHSWYIFINIYIYEYTPYIYDHICNVINVHLSLLLIPFCFYDFDCKWYRSVENYEELYKLLSYNVSANSNKTEDGDKQTTYLKEKSKLEIYEKDSKSEKDEMESYDVLILDKHEQNKNIIINQLENNNFDLFVEIKNNNSSGLFKRLLIEYIPILTTINVDDQFVYVIKFIDFRDFLLNTQNRNDNIYNNIIETYKFLNFTQFTKFEMNNINNDKKFELDENYYFLFNANNTSIDKDNVLKDSKSIIQFYYNFILNYCLNYFVDNYLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNN2</accession>
    <name>A0A1J1GNN2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00379100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526908.1">
        <property type="nucleotide sequence ID" value="XM_028670125.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNN2"/>
    <dbReference type="GeneID" id="39732321"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00379100"/>
    <dbReference type="OrthoDB" id="391710at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="127" mass="14649" checksum="BAA68D0C6A0F063C" modified="2017-02-15" version="1">MSESSNKILKAEIGIIKKVDLELFKNIILPFNGLVEEYNEENETAIVQFNIGIEKKHLEGLGNYTVKPMQFDLIETKDKNLRKRNINFIYDRVIIDEHDIISIFLNITLIAPVIFVLLSILILSSIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNQ4</accession>
    <name>A0A1J1GNQ4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ubiquitin-conjugating enzyme, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00162700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526739.1">
        <property type="nucleotide sequence ID" value="XM_028675182.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNQ4"/>
    <dbReference type="GeneID" id="39730152"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00162700"/>
    <dbReference type="OMA" id="HWTFVYA"/>
    <dbReference type="OrthoDB" id="7851174at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14314">
        <property type="entry name" value="UBA_II_E2_pyUCE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23800">
        <property type="entry name" value="UBCc_UBE2K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000083">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000088">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="7">
        <location>
            <begin position="9"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="6">
        <location>
            <begin position="159"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="4"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="3">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="202" mass="22950" checksum="15C18E83AB818377" modified="2017-02-15" version="1">MNSTSRSSKELLRLQKELKDIENENVEEIDAHIKDSNIFEWVGFIKGPSGTPYENGHFILDINIPNDYPYNPPKIKFSTKIWHPNISSQTGAICLDVLKNEWSPALTIRTALLSIQALLSDPQPDDPQDAEVAKMYKENYSLFLKTASVWTKTFATVPKKEPREVIIKKITEMGFTEDQAKNALIKANWNETLALNTLLENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNU5</accession>
    <name>A0A1J1GNU5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">PGAL8A_00383400</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 20">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526951.1">
        <property type="nucleotide sequence ID" value="XM_028670172.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNU5"/>
    <dbReference type="GeneID" id="39732364"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00383400"/>
    <dbReference type="OMA" id="NCIPSKG"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16454">
        <property type="entry name" value="RING-H2_PA-TM-RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029067">
        <property type="entry name" value="CDC48_domain_2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45977:SF4">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45977">
        <property type="entry name" value="TARGET OF ERK KINASE MPK-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54585">
        <property type="entry name" value="Cdc48 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="8 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="17">
        <location>
            <begin position="531"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="79"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="466"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="80"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="111"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="CRG94130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="577" mass="68602" checksum="5B1F0C85C7D6F8E5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNX0</accession>
    <name>A0A1J1GNX0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical], putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00067900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG92975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525797.1">
        <property type="nucleotide sequence ID" value="XM_028671199.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNX0"/>
    <dbReference type="GeneID" id="39729204"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00067900"/>
    <dbReference type="OMA" id="DSQFERR"/>
    <dbReference type="OrthoDB" id="276276at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004081">
        <property type="term" value="F:bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006167">
        <property type="term" value="P:AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006754">
        <property type="term" value="P:ATP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051325">
        <property type="entry name" value="Nudix_hydrolase_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21340:SF0">
        <property type="entry name" value="BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE [ASYMMETRICAL]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21340">
        <property type="entry name" value="DIADENOSINE 5,5-P1,P4-TETRAPHOSPHATE PYROPHOSPHOHYDROLASE MUTT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="2"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG92975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="148" mass="17537" checksum="429A6DF8C9DC4226" modified="2017-02-15" version="1">MKKNKTFGILIYRVEYNNSKNVLNNKSKIEFLFLKASYEFLFYKGLHEENENGLETAMRETFEETGLNKDKYKLLNFEKTLIYNVKDKTKETTYYLAGLLNNDENIKLSDEHTDFKWIHSNESDVYSLPDSFAELMKSAEEFIRKIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP42</accession>
    <name>A0A1J1GP42_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CPW-WPC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00396100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527078.1">
        <property type="nucleotide sequence ID" value="XM_028670314.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP42"/>
    <dbReference type="GeneID" id="39732491"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00396100"/>
    <dbReference type="OMA" id="YPCINSC"/>
    <dbReference type="OrthoDB" id="365677at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006387">
        <property type="entry name" value="CPW_WPC_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01492">
        <property type="entry name" value="CPW_WPC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09717">
        <property type="entry name" value="CPW_WPC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01099">
        <property type="entry name" value="CPW_WPC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012091308" evidence="2">
        <location>
            <begin position="21"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="domain" description="CPW-WPC" evidence="3">
        <location>
            <begin position="178"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="CPW-WPC" evidence="3">
        <location>
            <begin position="240"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="CPW-WPC" evidence="3">
        <location>
            <begin position="303"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="CPW-WPC" evidence="3">
        <location>
            <begin position="364"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="CPW-WPC" evidence="3">
        <location>
            <begin position="425"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="518" mass="61659" checksum="4C5CC6BAF78B6ACA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPC8</accession>
    <name>A0A1J1GPC8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyl-CoA synthetase, putative</fullName>
            <ecNumber evidence="3">6.2.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00405700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527174.1">
        <property type="nucleotide sequence ID" value="XM_028670419.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPC8"/>
    <dbReference type="GeneID" id="39732587"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00405700"/>
    <dbReference type="OMA" id="KWIKKHM"/>
    <dbReference type="OrthoDB" id="10253869at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272:SF3">
        <property type="entry name" value="LONG CHAIN ACYL-COA SYNTHETASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="2">
        <location>
            <begin position="132"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="223"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="732" mass="85034" checksum="8D7E9CFE00DAD7D5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPQ7</accession>
    <name>A0A1J1GPQ7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DnaJ protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00070600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525824.1">
        <property type="nucleotide sequence ID" value="XM_028674198.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPQ7"/>
    <dbReference type="GeneID" id="39729231"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00070600"/>
    <dbReference type="OMA" id="TRKPKHA"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026894">
        <property type="entry name" value="DnaJ_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052423">
        <property type="entry name" value="EMIR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44094">
        <property type="entry name" value="DNAJ HEAT SHOCK N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44094:SF8">
        <property type="entry name" value="DNAJ HEAT SHOCK N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14308">
        <property type="entry name" value="DnaJ-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="192"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="530" mass="61731" checksum="12018587B0EB9D5D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPS4</accession>
    <name>A0A1J1GPS4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00183400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527263.1">
        <property type="nucleotide sequence ID" value="XM_028670518.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPS4"/>
    <dbReference type="GeneID" id="39730361"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00183400"/>
    <dbReference type="OMA" id="FEAQKCE"/>
    <dbReference type="OrthoDB" id="341422at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36489:SF1">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36489">
        <property type="entry name" value="PROTEIN-COUPLED RECEPTOR GPR1, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="816" mass="93500" checksum="1BE47CECADB40D9F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPW0</accession>
    <name>A0A1J1GPW0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Carbon catabolite repressor protein 4, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00103300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526149.1">
        <property type="nucleotide sequence ID" value="XM_028673010.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPW0"/>
    <dbReference type="GeneID" id="39729558"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00103300"/>
    <dbReference type="OrthoDB" id="428734at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050410">
        <property type="entry name" value="CCR4/nocturin_mRNA_transcr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121">
        <property type="entry name" value="CARBON CATABOLITE REPRESSOR PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121:SF100">
        <property type="entry name" value="POLY(A)-SPECIFIC RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="251" mass="29487" checksum="B6A41049CD7F8EA8" modified="2017-02-15" version="1">MYKGKKIRIGTLNIFNNICHSIKEKFLNYDSEYIYNISRKNLLFKHLFSNSFDIICLQEVDLFMINELKKKCLEYNFTLYASPDNIKSSKNNNCIIYKKNFKLLDENFFDLNSVVSKYFMNYSSESRCEQKENDISHLQKLSGVYELITKGRVKNTHMEHPAQLRKDKAFYLLPELSIEPFKSAFKEINGNEPIFTNKTLSFSGCIDFIFYKELIPLSAKTIPSNLNDIKILPNEHFPSDHILLMSEFFVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPZ6</accession>
    <name>A0A1J1GPZ6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00407600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527193.1">
        <property type="nucleotide sequence ID" value="XM_028670441.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPZ6"/>
    <dbReference type="GeneID" id="39732606"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00407600"/>
    <dbReference type="OMA" id="DIHICTI"/>
    <dbReference type="OrthoDB" id="378766at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="244"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="370"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="65"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="272"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="379"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="482" mass="57569" checksum="AD67A20A77754595" modified="2017-02-15" version="1">MKELNNNNNLENKDEIIKLKREKLKPIQVRRSIKDILIDKNPCDYIYNYTGRNISIFPKDLLSNNENIKDSFNESENDKNNSEKEVISTISINEHEQKLLEELKELLKKDLSNEMKDNIKSLFIEVQEFYLEIKNDLKINYPSTEDLLKLYSTNDCSDKSKNAIWKSFCFYKLLSDQLNDLHISTISSYRLQCLKTIYRWYNKNKRILFNCKNDKKKINLFDEEINKNDSLNGNFDNTYASTLNEKTNLQNKNNDSIEIKENDENNENNENNEEKKKDIEEDPNEIKDSKSKNQKEYTKEFSEDFDKLLKEHIQITNEQNEKYEDIELNKKNEITDNESNNILNNYIYPYNTIISKIECEQKKESILKNNAHIENNNKSNEEKREEDYEHKSRENNTYEEYECKNFEKLNSDKFNFNSTLLGDEKDDFYQIPIDTKKIKELEEEIKKQKLLIKKKEIEIINSPIGIKFKDIFGNFQDIDINN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQK1</accession>
    <name>A0A1J1GQK1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acetyl-CoA acetyltransferase, putative</fullName>
            <ecNumber evidence="9">2.3.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00210100</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.9" evidence="9"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527519.1">
        <property type="nucleotide sequence ID" value="XM_028670803.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQK1"/>
    <dbReference type="GeneID" id="39730628"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00210100"/>
    <dbReference type="OMA" id="EPMRPGT"/>
    <dbReference type="OrthoDB" id="5404651at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003985">
        <property type="term" value="F:acetyl-CoA C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18919:SF156">
        <property type="entry name" value="ACETYL-COA ACETYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18919">
        <property type="entry name" value="ACETYL-COA C-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0630">Potassium</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase N-terminal" evidence="7">
        <location>
            <begin position="9"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase C-terminal" evidence="8">
        <location>
            <begin position="276"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="396" mass="43962" checksum="4CD1EFBCDD19489D" modified="2017-02-15" version="1">MLTSNLRKVFIVGYARTPIGSLCGSISHIPIHKLASATILKALERSQIEKDLIDCLIFGQSFSAGCGPLPLQKIIIAAGLNINTKSYLINNLCCSGLDSITLGYDLIKRGKDICIVGGMENMSQSPFFLKNLRTEKYNIGNNIFKDSIINDGYDFIINNKELKKNNNIELFCKKFKIPRIDLDEYVINSFKRASNAYSENLIQQEIFPLVIQKKNKLDIEKSVIDSDEIYKKCNIDNICNLSNESIITNHNIAPFGDGACAFILMSEKKINELQLNPLAEIITYDNASVYPSDFPLSISHSIMKCLKTINKSFVDYYEINESSALNVIFNIQNLKLDLSNVNINGGSLSLGNPTSVSGSRILASLITVLKNFDMKFGCASINNYLGSSTSIIVENL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQY8</accession>
    <name>A0A1J1GQY8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00223700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527655.1">
        <property type="nucleotide sequence ID" value="XM_028670953.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQY8"/>
    <dbReference type="GeneID" id="39730764"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00223700"/>
    <dbReference type="OMA" id="FENCCEM"/>
    <dbReference type="OrthoDB" id="377399at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="874" mass="105645" checksum="D874F59A050E788F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR44</accession>
    <name>A0A1J1GR44_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GTPase-activating protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00238200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527798.1">
        <property type="nucleotide sequence ID" value="XM_028671114.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR44"/>
    <dbReference type="GeneID" id="39730910"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00238200"/>
    <dbReference type="OMA" id="EYAPIIM"/>
    <dbReference type="OrthoDB" id="294251at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000001">
        <property type="entry name" value="TBC1 domain family member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF9">
        <property type="entry name" value="GTPASE ACTIVATING PROTEIN AND CENTROSOME-ASSOCIATED, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="503"/>
            <end position="691"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="759" mass="90921" checksum="0C087C7749CDCE68" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR60</accession>
    <name>A0A1J1GR60_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transcription factor with AP2 domain(S), putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ApiAP2</name>
        <name evidence="8" type="ORF">PGAL8A_00215300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527571.1">
        <property type="nucleotide sequence ID" value="XM_028670860.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR60"/>
    <dbReference type="GeneID" id="39730680"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00215300"/>
    <dbReference type="OrthoDB" id="386580at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00847">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="7">
        <location>
            <begin position="603"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="96"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="657" mass="78017" checksum="69591921769B35CC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR75</accession>
    <name>A0A1J1GR75_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GTPase-activating protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00232700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527743.1">
        <property type="nucleotide sequence ID" value="XM_028671051.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR75"/>
    <dbReference type="GeneID" id="39730854"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00232700"/>
    <dbReference type="OMA" id="FHTIYST"/>
    <dbReference type="OrthoDB" id="27140at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.80:FF:000061">
        <property type="entry name" value="GTPase-activating protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000031">
        <property type="entry name" value="TBC1 domain family member 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957:SF27">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="70"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="89"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="582" mass="69939" checksum="1CAE840FA402F6CF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRG8</accession>
    <name>A0A1J1GRG8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Small subunit rRNA processing KH domain protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00228700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527705.1">
        <property type="nucleotide sequence ID" value="XM_028671009.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRG8"/>
    <dbReference type="GeneID" id="39730814"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00228700"/>
    <dbReference type="OMA" id="TPLRNNW"/>
    <dbReference type="OrthoDB" id="1932641at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22392">
        <property type="entry name" value="KH-I_PNO1_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.10:FF:000074">
        <property type="entry name" value="Small subunit rRNA processing KH domain protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055211">
        <property type="entry name" value="KH_PNO1_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12826">
        <property type="entry name" value="RIBONUCLEASE Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12826:SF13">
        <property type="entry name" value="RNA-BINDING PROTEIN PNO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22891">
        <property type="entry name" value="KH_PNO1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="3">
        <location>
            <begin position="157"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="252" mass="29262" checksum="AB71456DC98F3E6F" modified="2017-02-15" version="1">MTKRIIKDSLSNQNKDQKTKIEKNDKKNIYEEKIKENNNRNILTLNKILEEKDTENKKKVKNKLICKKKISTNTNEMRIITIPRQRKSSVLKNWLELIKPIVTNLKLEIRMNKDKIEVRTCKLTEDKNNLQKSSDYIKAYLLGFSIEDALALLRIEDLYIESFQIQDVKMLKGDHLSRCIGRICGSNGSTKYAIENATKTRIVIAGDKIHILGSYNNIKMARYSICSLILGSTQGKIFNKLNILAKRLKERF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRH0</accession>
    <name>A0A1J1GRH0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00250700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527918.1">
        <property type="nucleotide sequence ID" value="XM_028671247.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731035"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00250700"/>
    <dbReference type="OMA" id="YMLCKVE"/>
    <dbReference type="OrthoDB" id="10255512at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37410">
        <property type="entry name" value="ADHESIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37410:SF1">
        <property type="entry name" value="FACTOR, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="416"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1146"/>
            <end position="1213"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="130"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="226"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="367"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="440"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="452"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="472"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1146"/>
            <end position="1167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1174"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1192"/>
            <end position="1213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1481" mass="176037" checksum="848F7E3CC05C7A30" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRI0</accession>
    <name>A0A1J1GRI0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00246800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527882.1">
        <property type="nucleotide sequence ID" value="XM_028671207.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730996"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00246800"/>
    <dbReference type="OMA" id="MYISYYT"/>
    <dbReference type="OrthoDB" id="372060at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="398"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="203"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="130"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="399"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1410" mass="169960" checksum="8D5F73DEE4A1EB37" modified="2017-02-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRN4</accession>
    <name>A0A1J1GRN4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00166000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526773.1">
        <property type="nucleotide sequence ID" value="XM_028675219.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRN4"/>
    <dbReference type="GeneID" id="39730186"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00166000"/>
    <dbReference type="OMA" id="CILIENT"/>
    <dbReference type="OrthoDB" id="376780at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="136"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="163"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="139"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="243" mass="28805" checksum="E47CE96175FE5785" modified="2017-02-15" version="1">MNSLKDYYSNCLYACSPEKYIIDQNEIEIPDTAKTNLSFRIFDIYNSTISSFSVKDNHLKSLKLNLNDNENIRIKKQKKNHKNLDKIKILDNFFFNFENNNNNTHKYNGRHENKKECIFIENTFDLELFNKSSIQNKPLDNKKKNTSNIKKENNLKGNEKKSVITKNKKYQKLNSEKEQKEQKEEEEKKEINLLNKELKKKNRINDNKKKGSDKDIYEMLKINGKIMKTSKINIPKINLSKIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRY5</accession>
    <name>A0A1J1GRY5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CPW-WPC family protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00243600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527851.1">
        <property type="nucleotide sequence ID" value="XM_028671172.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRY5"/>
    <dbReference type="GeneID" id="39730964"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00243600"/>
    <dbReference type="OMA" id="YTLPCPK"/>
    <dbReference type="OrthoDB" id="373941at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006387">
        <property type="entry name" value="CPW_WPC_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01492">
        <property type="entry name" value="CPW_WPC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09717">
        <property type="entry name" value="CPW_WPC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01099">
        <property type="entry name" value="CPW_WPC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012249888" evidence="1">
        <location>
            <begin position="23"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="CPW-WPC" evidence="2">
        <location>
            <begin position="83"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="CPW-WPC" evidence="2">
        <location>
            <begin position="152"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="CPW-WPC" evidence="2">
        <location>
            <begin position="218"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="CPW-WPC" evidence="2">
        <location>
            <begin position="280"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="CPW-WPC" evidence="2">
        <location>
            <begin position="342"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="462" mass="54181" checksum="E40FEADA43133D4B" modified="2017-02-15" version="1">MSRHNFFMIIIALIGIINTIFCIPFNQNENKKVESSLSSNGLLKNVVKHSPKISEEEINKSEIKIIKKAHEEENKKLTKLGKCIKDYTLSCPKYWTKNTTENGKITCVADSEYNGFCITNQSFENFTENDKMNFESSCNVEWPCKTISKDTCEDGKKDYNNPCPEGFLVQDDNSCKADITVYRGMCNSNNIKFTHMSDEEKENWSISCEAYWPCYKECSSEQFLSNCPKDWNEINLYECIPTQNYRGICKGKKNFKYFTISMKKSFEEKCKTRFLCSNSCEKNYEQDCPMNWLAEKGYCLAPHTFDLCNKKKLSIENLTTKDKQFFEKECSVNWPCKKKNFCEMDWNFECPENWEKEYLKNQKEQYICKSPSLYKGKCNNIFLTNNSNEYIKREVASNCNAPWPCIDEKKKNSFDPTEHKINNQDNFPNEINGPITQEGKIYEKKKYTIEDRKNSSFFDIMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRY8</accession>
    <name>A0A1J1GRY8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Cytochrome b-c1 complex subunit 9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00151100</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UQCR10/QCR9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526624.1">
        <property type="nucleotide sequence ID" value="XM_028675054.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRY8"/>
    <dbReference type="GeneID" id="39730035"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00151100"/>
    <dbReference type="OMA" id="KHNSRYW"/>
    <dbReference type="OrthoDB" id="9970435at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045275">
        <property type="term" value="C:respiratory chain complex III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.260">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008027">
        <property type="entry name" value="QCR9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036656">
        <property type="entry name" value="QCR9_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05365">
        <property type="entry name" value="UCR_UQCRX_QCR9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81514">
        <property type="entry name" value="Subunit X (non-heme 7 kDa protein) of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG93802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="95" mass="11509" checksum="03065FB059628F18" modified="2017-02-15" version="1">MVFGSPFSDTYPSFIWKSLKKSRKDKDMFNPFFQALNKTKIYDHILKYNTRYWLFVVTGGCVTSYFWGVWFNNKWKQINKGKLYIDCPYTYPEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS42</accession>
    <name>A0A1J1GS42_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SprT-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00249400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527907.1">
        <property type="nucleotide sequence ID" value="XM_028671235.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS42"/>
    <dbReference type="GeneID" id="39731022"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00249400"/>
    <dbReference type="OMA" id="SVQVKWS"/>
    <dbReference type="OrthoDB" id="5236983at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044245">
        <property type="entry name" value="Spartan"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006640">
        <property type="entry name" value="SprT-like_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055220">
        <property type="entry name" value="SPRTN_ZBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21220">
        <property type="entry name" value="DNA-DEPENDENT METALLOPROTEASE SPRTN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21220:SF0">
        <property type="entry name" value="DNA-DEPENDENT METALLOPROTEASE SPRTN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10263">
        <property type="entry name" value="SprT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22934">
        <property type="entry name" value="SPRTN_ZBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00731">
        <property type="entry name" value="SprT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SprT-like" evidence="4">
        <location>
            <begin position="182"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="127"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="468" mass="55684" checksum="AB2EEB26B5EF4938" modified="2017-02-15" version="1">MNADVKKLTSVENEYLEKCGKKRRQKTIIDEIEFNNDTNKEVKNITNIMDKIDNKYQIKNENEINHSYQIKDIKQISSEKSNNNDNNEYEEIKSSIKINEEESEDDYDTLEVIRQLSSIHIESDNDNDKEKKAYNKKENKNIKIKKNKNNKNKRSSLIFDISEIECVEDAVIYDESKDTIFPDLKELFSEYNVKYFFNKLETVEVKWSNKMKLCAGICIFKKSGYCCIRLSLPLLKLRKIKEYRETLLHEMIHAFLFLTRKNSIHDGHGPEFKKHMYRINKATGLSITIYHSFHDEVNFYRNHIWRCTGVCRTYPPHFGYVRRSMNRPPSSKEKWWRRHSLYCGGHFVKINEKKSTTNEKSGDMNKKGDFKIRLENILDKKTNNKKDNVEFEKRDDNMEEDMINDEIIILDSPDDLKEKKPNEEIDIIDLIKNLFSDNKEKILSFPDITVDYHKAFKSQKYFEIDSDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS97</accession>
    <name>A0A1J1GS97_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA/RNA-binding protein Alba 4, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ALBA4</name>
        <name evidence="2" type="ORF">PGAL8A_00258500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527993.1">
        <property type="nucleotide sequence ID" value="XM_028671330.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS97"/>
    <dbReference type="GeneID" id="39731114"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00258500"/>
    <dbReference type="OMA" id="YICSVNA"/>
    <dbReference type="OrthoDB" id="447602at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21101">
        <property type="entry name" value="MAF1-ALBA4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036882">
        <property type="entry name" value="Alba-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82704">
        <property type="entry name" value="AlbA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="371" mass="42169" checksum="EE56D3EA11884C3C" modified="2017-02-15" version="1">MENDKRYNQKQNNNDENEFPNSKVLLISVKRTRRFLERTARELLAGGTRYIILSGLGDALPLCVQLQSSLQSKNAAVVVKIETSYSYFNSNYSYTPGLKIYMEKHPDFKGSRISPGYVSFHEKTDTFTPIYDENPNEYICSLNAGDNNLYVGGDGINGAFFELLSSHNQSVDKYESLFKELLNKAVKENGEKTDEEIKSVLYDNVDKKYPDVKLALCRIRNCLKKGNDYTTGSVFIVTFKKNFPYKKEKNMGMVYVVGPKGKNCNSVEEFLDAVQETAENLMTALCDYNGLVKREEIKHVRMNTCRICLFSGNIYKHPNASKLDVAKSILNGLAVGYRHGPSPRLNFAYDENVFKDAWIETTGLQVFNHND</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSD7</accession>
    <name>A0A1J1GSD7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">E3 SUMO-protein ligase PIAS, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PGAL8A_00167100</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PIAS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526784.1">
        <property type="nucleotide sequence ID" value="XM_028669987.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730197"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00167100"/>
    <dbReference type="OMA" id="YEFILET"/>
    <dbReference type="OrthoDB" id="28127at2759"/>
    <dbReference type="UniPathway" id="UPA00886"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061665">
        <property type="term" value="F:SUMO ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16650">
        <property type="entry name" value="SP-RING_PIAS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004181">
        <property type="entry name" value="Znf_MIZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10782:SF4">
        <property type="entry name" value="TONALLI, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10782">
        <property type="entry name" value="ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02891">
        <property type="entry name" value="zf-MIZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51044">
        <property type="entry name" value="ZF_SP_RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="15" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SAP" evidence="13">
        <location>
            <begin position="14"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="SP-RING-type" evidence="14">
        <location>
            <begin position="344"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="861"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="1247"/>
            <end position="1289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="870"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="886"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="929"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="970"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1019"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1029"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="1039"/>
            <end position="1090"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1106"/>
            <end position="1127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1128"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1139"/>
            <end position="1175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG93963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1667" mass="195595" checksum="69C08B25E754918A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSK2</accession>
    <name>A0A1J1GSK2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Early transcribed membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ETRAMP</name>
        <name evidence="2" type="ORF">PGAL8A_00001300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528059.1">
        <property type="nucleotide sequence ID" value="XM_028671403.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSK2"/>
    <dbReference type="GeneID" id="39728535"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00001300"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006389">
        <property type="entry name" value="Early_transc_mb_plasmodium"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01495">
        <property type="entry name" value="ETRAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09716">
        <property type="entry name" value="ETRAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="191" mass="21958" checksum="9B7AB1350304A7CC" modified="2017-02-15" version="1">MKASKLLFFLSSFLIINILTPYLFNANVFFVSADGKIQEINKDIEKKNKKKKIILISSIAAGLVMLAASILGIGNCIKRKNDRMKGYTYRIDTWPDNDIRRVGTEISQKASKRGLKETIVNFHKGKQEGPSDKTLKSYVFDEIKKSGVVFSERQISDMMYYVLSDVAVMEKHWRNFPEYLPSLHLKKDLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSP9</accession>
    <name>A0A1J1GSP9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Translocation associated membrane protein, putative</fullName>
            <ecNumber evidence="8">2.3.1.24</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">TRAM</name>
        <name evidence="8" type="ORF">PGAL8A_00275500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.24" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528366.1">
        <property type="nucleotide sequence ID" value="XM_028671744.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSP9"/>
    <dbReference type="GeneID" id="39731287"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00275500"/>
    <dbReference type="OMA" id="KWKENFW"/>
    <dbReference type="OrthoDB" id="537032at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050291">
        <property type="term" value="F:sphingosine N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016439">
        <property type="entry name" value="Lag1/Lac1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560:SF0">
        <property type="entry name" value="LD18904P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560">
        <property type="entry name" value="LONGEVITY ASSURANCE FACTOR 1 LAG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005225">
        <property type="entry name" value="LAG1_LAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4 5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="217"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="299"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="7">
        <location>
            <begin position="119"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="359" mass="43658" checksum="34CB130BB31E5552" modified="2017-02-15" version="1">MTTLYLHTLKEYFLSSQNKGYIEAYLINPKLSKWDFVICLLMFVFITILRFLFSGVNKVMVRNDNILYKLAKNSLLDKINKKWNVAKEGQLYKWKENFWFVIWHIFSFSYNFILLLYMSGYFDNKNGWIKMMIKEPTGKWFFLVTEEEFRENKRGWPFMYTNNYVYYFYILQISYWSSCLFYLNYEIKRKDFYIFVLHHISTIILLIYSHVLNFWRVGLLILLIHDIVDITLYSSKLLNYSNLKSRILLPLFYILFVLSYFFFRIFLYFYYIVLPLSNMKIIKTYTDGFISSHFDVPGGVVLIVFLWALMFMHCYWFYLILRMSRVFIVKTVKNEKITDIRSDNEDDNASTIESIKKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSZ2</accession>
    <name>A0A1J1GSZ2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00181600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527245.1">
        <property type="nucleotide sequence ID" value="XM_028670498.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730343"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00181600"/>
    <dbReference type="OMA" id="DENVRNY"/>
    <dbReference type="OrthoDB" id="382817at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="378"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="411"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="628"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="980"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1191"/>
            <end position="1209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1229"/>
            <end position="1247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="467"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1296"/>
            <end position="1323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1336" mass="162263" checksum="0D1627A69DFDEC6D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT03</accession>
    <name>A0A1J1GT03_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA mismatch repair protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00277200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528383.1">
        <property type="nucleotide sequence ID" value="XM_028671763.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731305"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00277200"/>
    <dbReference type="OrthoDB" id="10252754at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.10">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007695">
        <property type="entry name" value="DNA_mismatch_repair_MutS-lik_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016151">
        <property type="entry name" value="DNA_mismatch_repair_MutS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053276">
        <property type="entry name" value="MtDNA_mismatch_repair_MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48448">
        <property type="entry name" value="MUTL PROTEIN ISOFORM 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48448:SF1">
        <property type="entry name" value="MUTL PROTEIN ISOFORM 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01624">
        <property type="entry name" value="MutS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55271">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="5">
        <location>
            <begin position="1006"/>
            <end position="1206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1458" mass="174034" checksum="AFB14C0197DE5AFC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT48</accession>
    <name>A0A1J1GT48_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutamate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">GDH1</name>
        <name evidence="10" type="ORF">PGAL8A_00288100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homohexamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 8">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528492.1">
        <property type="nucleotide sequence ID" value="XM_028671884.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT48"/>
    <dbReference type="GeneID" id="39731414"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00288100"/>
    <dbReference type="OMA" id="GNIWEIP"/>
    <dbReference type="OrthoDB" id="6718861at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004354">
        <property type="term" value="F:glutamate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05313">
        <property type="entry name" value="NAD_bind_2_Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.285.10:FF:000001">
        <property type="entry name" value="Glutamate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10860:FF:000002">
        <property type="entry name" value="Glutamate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000030">
        <property type="entry name" value="Glutamate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.285.10">
        <property type="entry name" value="Glutamate Dehydrogenase, chain A, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006095">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006097">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033524">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014362">
        <property type="entry name" value="Glu_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050724">
        <property type="entry name" value="Glu_Leu_Phe_Val_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033922">
        <property type="entry name" value="NAD_bind_Glu_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006929">
        <property type="entry name" value="PRK09414.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43571">
        <property type="entry name" value="NADP-SPECIFIC GLUTAMATE DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43571:SF1">
        <property type="entry name" value="NADP-SPECIFIC GLUTAMATE DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02812">
        <property type="entry name" value="ELFV_dehydrog_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000185">
        <property type="entry name" value="Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00082">
        <property type="entry name" value="GLFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00074">
        <property type="entry name" value="GLFV_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal" evidence="9">
        <location>
            <begin position="224"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="401"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="7">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG95684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="470" mass="52584" checksum="86AA602D782DC8D6" modified="2017-02-15" version="1">MHHKRDKTGRFLLIDKNSGNYESLIVEEMNNIYERVKMLDPNQKEFLQAFHEILFSLKPLFIEEPKYLPIIEMLAEPERVVQFRVCWLDDNGIQRKNRAFRVQFSSLLGPYKGGLRFHPSVNLSIVKFLGFEQIFKNSLTGLSMGGGKGGSDFDPKGKSDSEILKFCQSFMNELYRHIGPHTDVPAGDIGVGGKEIGYLFGQYKKIVGNFNGTLTGKNVKWGGSHLRVEATGYGLVYFVLEVLKSLNVPISNKTAVISGSGNVALYCLEKLLQLNVKVLTLSDSNGYIYEPNGFNKENLKFLIELKEERKGRIKEYLGHSSTAKYFPNEKPWGIPCTLAFPCATENEIDLSDAKTLHKNGCILVGEGANMPSTIEAIDYFKKNNIILCPAKAANAGGVAISGLEISQNSQCSQWTRETVDEKLKEIMRNIFISSSENALKYTNNKYDLQTGANIAGFLKVAESYIEQGCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT53</accession>
    <name>A0A1J1GT53_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00187800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000026">
        <property type="protein sequence ID" value="CRG94483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527301.1">
        <property type="nucleotide sequence ID" value="XM_028670561.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT53"/>
    <dbReference type="GeneID" id="39730405"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00187800"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="223" mass="26882" checksum="3E515E1338B80FEE" modified="2017-02-15" version="1">MKTLTLYLKITTFLLLIWMYQCFYNCDSYRTLIDKNILQTKNELKHERVLTEGDIEGKKQTSAKGCLEECPLNNKKKKCKNPDKYENPCDRWQRVNTPLLWERFYGETSNMDPKWIDQKWNVEWNDISAYKLNELSLIYDRQDISEEDKEKKIDSVKKELYIEYVKFLFECKKEVLKNKTECEPKKEMRDNKKESESTEVIRENKTESETKKEQGINEIKKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTJ1</accession>
    <name>A0A1J1GTJ1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Hsp70-Hsp90 organising protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Stress-inducible protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">HOP</name>
        <name evidence="14" type="ORF">PGAL8A_00305800</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Acts as a co-chaperone and mediates the association of the chaperones HSP70 and HSP90 probably facilitating substrate transfer from HSP70 to HSP90. Stimulates HSP70 ATPase activity and, in contrast, inhibits HSP90 ATPase activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer. Homodimer. Forms a complex composed of HOP and chaperones HSP70 and HSP90; the interaction is stronger in the absence of ATP. Interacts (via TPR 1, 2, 3, 7, 8 and 9 repeats) with HSP70 (via C-terminus); the interaction is direct and is stronger in the absence of ATP. Interacts (via TPR 4, 5 and 6 repeats) with HSP90 (via C-terminus); the interaction is direct.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528654.1">
        <property type="nucleotide sequence ID" value="XM_028672063.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTJ1"/>
    <dbReference type="GeneID" id="39731591"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00305800"/>
    <dbReference type="OMA" id="LCEYKLG"/>
    <dbReference type="OrthoDB" id="2423701at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000210">
        <property type="entry name" value="Hsp70/Hsp90 organizing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000020">
        <property type="entry name" value="Stress-induced phosphoprotein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.260.100:FF:000002">
        <property type="entry name" value="Stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041243">
        <property type="entry name" value="STI1/HOP_DP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006636">
        <property type="entry name" value="STI1_HS-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22904:SF523">
        <property type="entry name" value="STRESS-INDUCED-PHOSPHOPROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22904">
        <property type="entry name" value="TPR REPEAT CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17830">
        <property type="entry name" value="STI1-HOP_DP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13414">
        <property type="entry name" value="TPR_11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00727">
        <property type="entry name" value="STI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="10">
        <location>
            <begin position="7"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="10">
        <location>
            <begin position="239"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="10">
        <location>
            <begin position="314"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="10">
        <location>
            <begin position="374"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="10">
        <location>
            <begin position="408"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="10">
        <location>
            <begin position="442"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="STI1" evidence="13">
        <location>
            <begin position="509"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="200"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="327"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="200"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="222"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00056105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00066016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00074766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00076447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG95846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="560" mass="66151" checksum="4EB8EC978B0017DD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTM7</accession>
    <name>A0A1J1GTM7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00411000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527224.1">
        <property type="nucleotide sequence ID" value="XM_028670475.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTM7"/>
    <dbReference type="GeneID" id="39732640"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00411000"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="156" mass="18301" checksum="A52EC54978D7F0EE" modified="2017-02-15" version="1" fragment="single">MSLLYNKGCEDSGEFIKCLMSLCPINPNKLQSSYCTVEPKFVITQRPFNNALINISKNIFTYEHYGPDYKSSITILSNEDNDGILILYEYNPWYFKYPKETYLCRLRNKNQKISLCESINVNYIGKSISFNSYDIINRDDKKNNQISMKHLKNPKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTP2</accession>
    <name>A0A1J1GTP2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">mRNA guanylyltransferase</fullName>
            <ecNumber evidence="2">2.7.7.50</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00286200</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a 5'-end diphospho-ribonucleoside in mRNA + GTP + H(+) = a 5'-end (5'-triphosphoguanosine)-ribonucleoside in mRNA + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:67012"/>
            <dbReference type="Rhea" id="RHEA-COMP:17165"/>
            <dbReference type="Rhea" id="RHEA-COMP:17166"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:167616"/>
            <dbReference type="ChEBI" id="CHEBI:167617"/>
            <dbReference type="EC" id="2.7.7.50"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:67013"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.50" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528473.1">
        <property type="nucleotide sequence ID" value="XM_028671862.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTP2"/>
    <dbReference type="GeneID" id="39731395"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00286200"/>
    <dbReference type="OrthoDB" id="200924at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004484">
        <property type="term" value="F:mRNA guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006370">
        <property type="term" value="P:7-methylguanosine mRNA capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07895">
        <property type="entry name" value="Adenylation_mRNA_capping"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001339">
        <property type="entry name" value="mRNA_cap_enzyme_adenylation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013846">
        <property type="entry name" value="mRNA_cap_enzyme_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051029">
        <property type="entry name" value="mRNA_Capping_Enz/RNA_Phosphat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10367">
        <property type="entry name" value="MRNA-CAPPING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10367:SF17">
        <property type="entry name" value="MRNA-CAPPING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03919">
        <property type="entry name" value="mRNA_cap_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01331">
        <property type="entry name" value="mRNA_cap_enzyme"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0506">mRNA capping</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="mRNA capping enzyme adenylation" evidence="11">
        <location>
            <begin position="40"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="mRNA capping enzyme adenylation" evidence="11">
        <location>
            <begin position="268"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="mRNA capping enzyme C-terminal" evidence="12">
        <location>
            <begin position="330"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG95665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="462" mass="54295" checksum="5A6F7295841D94CA" modified="2017-02-15" version="1">MIIDIYNPGEKIENEFLKEKIRSKINEMLNWKRKGFPGSNPVSLTNHNIKNLFNKEYIICEKTDGVRYFLFIASNTTFLIDRNYEIFKNDMHIPLKEDLSKKQQLTLLDGELVEDTIFHERKGIEEKKIVYLIYDGLYIQRRDITNLSYLDRLKYVYNYVITPLKIYKKKILKNKNFNYSQESVCNDVSLKKRKYNVGSEYVEESKCLSVNVDNSRNSPNTSDKKISNYNETDCIDYKRDSCINIDNEINYSDSDINDDISSSDSFINDENEYPFEIYLKDFYTIDKICELTKIMKKLPHPSDGIIFTPLNSSYVTGNFYHLLKWKPLNLNTVDFGIETVYDENNMPNKFELFIAINGVRTSYKCYLAQYGDVYKELLQLALNNKISHYIVECYYVSKNIYSICKNDNSTETEIEGGWIAQKIRYDKNIPNDISTLNKVIQSILDNITIDSLIKEILRNKKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTZ1</accession>
    <name>A0A1J1GTZ1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00190900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000028">
        <property type="protein sequence ID" value="CRG94512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527328.1">
        <property type="nucleotide sequence ID" value="XM_028670591.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTZ1"/>
    <dbReference type="GeneID" id="39730434"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00190900"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="298"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="329" mass="38823" checksum="4FFC719D02F77F31" modified="2017-02-15" version="1">MSLLYNEGCEDSGDFTKCLMSLCSINPNKLQSSYCIRAPEFVITQRPFNNVLINISKNIFTYEHYGPDYESSITILSNEDKDGILILYEYNPLYFKYPKETYLCRLRNKNQKISLCESINVNYIGKSISFNSYDIINRDDKKNNLISMKHLENPKHRIIKLKYNEIILKKDSCHHAKTKYNPHHTCRYIICEKDDHGNTMCANSNYNGKLIHLLDYYTFANLKEERIVYLPNKCLKSDSNLLCTPYMCIKNNLNESYSCEYEEISIVKNIFPSPETFKAISTNHQAIYHESNLRSSSVYAMTLMPFLIIFIFFFCYIYKIFRKKRRKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU13</accession>
    <name>A0A1J1GU13_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00293600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528539.1">
        <property type="nucleotide sequence ID" value="XM_028671936.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU13"/>
    <dbReference type="GeneID" id="39731469"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00293600"/>
    <dbReference type="OrthoDB" id="372823at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="197"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="262"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="311" mass="36739" checksum="51FD60911A4C60CD" modified="2017-02-15" version="1">MDSENVDKNEKNLINLGTILKPVNINEKKKKKKKNGIKLELENDDKEKMGENIDEIKTETIEKSNDDENLEENISKKDNTENVEFHKLYESDDNISRKSSLNISNKNDSHKKKKVKAKLNTLMLQSYFHKSYDKVSNVLKKTSKSFLKKNSISNEKKINNVDNLKDTCNDELTTPTVNMDKQTYDEYNFFEKNSVIINKYLDDNINLEKQNEKLLKKYKKLLENNDSTKFLEELKELLDEKILLIKTLIYYKNICINYKKDLNKYKNSFEIFNSEKEQLSQNIITLKKHIDFLNNNIHSDLKKENEITDLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU19</accession>
    <name>A0A1J1GU19_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tetratricopeptide SHNi-TPR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00316400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528759.1">
        <property type="nucleotide sequence ID" value="XM_028672180.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU19"/>
    <dbReference type="GeneID" id="39731697"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00316400"/>
    <dbReference type="OMA" id="EFARKCY"/>
    <dbReference type="OrthoDB" id="5587616at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034080">
        <property type="term" value="P:CENP-A containing chromatin assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006335">
        <property type="term" value="P:DNA replication-dependent chromatin assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051730">
        <property type="entry name" value="NASP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019544">
        <property type="entry name" value="Tetratricopeptide_SHNi-TPR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15081:SF1">
        <property type="entry name" value="NUCLEAR AUTOANTIGENIC SPERM PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15081">
        <property type="entry name" value="NUCLEAR AUTOANTIGENIC SPERM PROTEIN NASP -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10516">
        <property type="entry name" value="SHNi-TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="Tetratricopeptide SHNi-TPR" evidence="5">
        <location>
            <begin position="159"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="252"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="332" mass="39006" checksum="2C30DDC97642C3E4" modified="2017-02-15" version="1">MSEQEITADDSSNANVESEVDEQKELLKKRTANELFDMGKLEFKENKNYEVAAERFSMAVEKKIKELKIEGNIHIDLREFYLCFADALLTKEEEKNDLFEFLKKKKKIEVPDLDDITDKEEVTDEQLAFEMFEFARKCYELLIEKNKEVPKKDILNYTYVFIRLGDINLLNHFFPEALKEYEKCVELREKHKVGDENLIAPLISLSQSYMFCGKRKGAVEYFEKVKKILLDVRQKTTPLPENTNEKIIRDTYDDVQIQINDLKRQIEEEGEEGKELGSQTKAKELVITTKSEFDKAILNKEKDEVTKITISRISDEEHATKKRRIDLSKYKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU36</accession>
    <name>A0A1J1GU36_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA polymerase alpha subunit B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00222700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA polymerase alpha subunit B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527645.1">
        <property type="nucleotide sequence ID" value="XM_028670942.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU36"/>
    <dbReference type="GeneID" id="39730754"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00222700"/>
    <dbReference type="OMA" id="CRPSEMK"/>
    <dbReference type="OrthoDB" id="336885at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005658">
        <property type="term" value="C:alpha DNA polymerase:primase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007185">
        <property type="entry name" value="DNA_pol_a/d/e_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016722">
        <property type="entry name" value="DNA_pol_alpha_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054300">
        <property type="entry name" value="OB_DPOA2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23061">
        <property type="entry name" value="DNA POLYMERASE 2 ALPHA 70 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23061:SF12">
        <property type="entry name" value="DNA POLYMERASE ALPHA SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04042">
        <property type="entry name" value="DNA_pol_E_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22062">
        <property type="entry name" value="OB_DPOA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018300">
        <property type="entry name" value="DNA_pol_alph_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA polymerase alpha subunit B OB" evidence="7">
        <location>
            <begin position="93"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="DNA polymerase alpha/delta/epsilon subunit B" evidence="6">
        <location>
            <begin position="249"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF22062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="510" mass="60423" checksum="5B4F08622CAF046F" modified="2017-02-15" version="1" fragment="single">EVFDYIERNKHKNNFHKLFEDYLEVYNKRLLKNENLVKDNIVYEYEYVKQYNNQLIGTDGINCNNKYNWYINSINTINENYQFLGLDTNVISECINKKISLFLELFLKYSEKLNLNIEVSPILNMNEEDCYIFGRIYTDNEINISESNIILEGNVKWNNGDKAQLLNLNNMKNLFFFLGQILAIKGKKEINQYSIKYYVSNIYAGLPTHLNVKIDKEFLLNYFNCNEIEEDSRIHDDISQLYNNDNIHIMVCNGHIYNDNDYNDNLNNFLKIVNEKSPHVVLIFGPFLFIRNFSETIQKIGDINVIYDNIFKKIIKIAKNEHLEKTHFFIIPSIYDSINIYPLPQPPFFYENSNNLSNVHFLSNPSYIYINELKIALTSCDVVYNLSKNLLCKPSEMKLFYLFEQIIRQISFFPSYPCEYNIETTKFNNLLFHPNKLPDIFLFPSYTNEKSYIKEVHKKLFICAYSIDVNKAHPSNFFSNIYILPPKETHELSKRVILENVFVHQNKINA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUE0</accession>
    <name>A0A1J1GUE0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DnaJ homolog subfamily C member 16</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Endoplasmic reticulum DNA J domain-containing protein 8</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00336000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Plays an important role in regulating the size of autophagosomes during the formation process.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528950.1">
        <property type="nucleotide sequence ID" value="XM_028672393.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUE0"/>
    <dbReference type="GeneID" id="39731890"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00336000"/>
    <dbReference type="OMA" id="FFISYND"/>
    <dbReference type="OrthoDB" id="445556at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052842">
        <property type="entry name" value="ER_Co-chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45184:SF2">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_102, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45184">
        <property type="entry name" value="DNAJ PROTEIN ERDJ3A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0072">Autophagy</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="J" evidence="6">
        <location>
            <begin position="48"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="7">
        <location>
            <begin position="161"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="546" mass="63591" checksum="A73ED82A7582E5DD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUH4</accession>
    <name>A0A1J1GUH4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ubiquitin domain-containing protein DSK2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">DSK2</name>
        <name evidence="4" type="ORF">PGAL8A_00340300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528990.1">
        <property type="nucleotide sequence ID" value="XM_028672438.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUH4"/>
    <dbReference type="GeneID" id="39731933"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00340300"/>
    <dbReference type="OMA" id="ARAQMEM"/>
    <dbReference type="OrthoDB" id="267397at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14399">
        <property type="entry name" value="UBA_PLICs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16106">
        <property type="entry name" value="Ubl_Dsk2p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000287">
        <property type="entry name" value="Ubiquitin domain-containing protein DSK2,putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015496">
        <property type="entry name" value="Ubiquilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10677:SF3">
        <property type="entry name" value="FI07626P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10677">
        <property type="entry name" value="UBIQUILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="3">
        <location>
            <begin position="3"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="2">
        <location>
            <begin position="333"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="380" mass="42131" checksum="6A78C2D873C95DF3" modified="2017-02-15" version="1">MVINVSFKVTGGKEFTISIEPDITVLDLKKKCCDHVDIPVEAQRIIFKGKILKDKESLSTYNVADGNTMHLVRSAIPTKEPEEEKENNKNESSSNQNTNSNDNLSDLSDNPLVQMLLQSGTGDVNNFNSGTGSGDNLNFGNFANLLNSNGGEFNRDTISSLLNNPLARSLLNELSNNPEMLTNLVSNNPILRNTFSQSPIMQPVLENPNLLREFMRPEVLQAGLQIENALNMNNNNNNNNNSSQRGIRMEDLLNNLNNFTNTNTSANNTDNNNPNENNNNSNINNINSLFQSQELLQTFQQVMRANRNLANLNFPNSSQNLDFNSSNVTDNRSPEEKYASQLLSLQEMGFIDNAANIQALQETGGDVNSAVTRLLEKGFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUV0</accession>
    <name>A0A1J1GUV0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00353900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529126.1">
        <property type="nucleotide sequence ID" value="XM_028672589.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUV0"/>
    <dbReference type="GeneID" id="39732069"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00353900"/>
    <dbReference type="OMA" id="CYSHKGV"/>
    <dbReference type="OrthoDB" id="379355at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="67" mass="7469" checksum="3AB7F5700176DD9C" modified="2017-02-15" version="1">MRSCYSHKGTSPGKHTGKCVSYDSIGKTDIQSANNGEYSYCTICGIVHKDPHKQALYPLREDQCRCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUV8</accession>
    <name>A0A1J1GUV8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GrpE protein homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00351300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the GrpE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529100.1">
        <property type="nucleotide sequence ID" value="XM_028672560.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUV8"/>
    <dbReference type="GeneID" id="39732043"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00351300"/>
    <dbReference type="OMA" id="KNEKCNT"/>
    <dbReference type="OrthoDB" id="201635at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001405">
        <property type="term" value="C:PAM complex, Tim23 associated import motor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00446">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.22.10:FF:000002">
        <property type="entry name" value="GrpE protein homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.20.20:FF:000015">
        <property type="entry name" value="GrpE protein homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.22.10">
        <property type="entry name" value="Head domain of nucleotide exchange factor GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01151">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000740">
        <property type="entry name" value="GrpE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013805">
        <property type="entry name" value="GrpE_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009012">
        <property type="entry name" value="GrpE_head"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237">
        <property type="entry name" value="GRPE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237:SF23">
        <property type="entry name" value="GRPE PROTEIN HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01025">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00773">
        <property type="entry name" value="GRPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58014">
        <property type="entry name" value="Coiled-coil domain of nucleotide exchange factor GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51064">
        <property type="entry name" value="Head domain of nucleotide exchange factor GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01071">
        <property type="entry name" value="GRPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="62"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="272" mass="32066" checksum="D18ECE9AB8DA4F4A" modified="2017-02-15" version="1">MKYANFLKRGSIARYSSNLYGMQLFHSRRYYLNFFRNTNKKIGYQSYSTSSMYDEAYSNGENFKKEQKVENKEKENNLNENENVINQKETKNIEKNIEEIDYENYNKIDLIKEIKKVKKDMDEKIIDNKILKEKYLSVLAENENLRNRYIKEIENNKVYCITNFAKSLLDVADNLSLAIQNINEESLKHNEEISNIHKGIQMTETILHNIFNKYGINKYNPINEKFNPSLHEAIFEINDNTKEKGTVATVIQQGYKIKDRILRAAKVGVVKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUW7</accession>
    <name>A0A1J1GUW7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Mitochondrial import inner membrane translocase subunit TIM44, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00352100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tim44 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529108.1">
        <property type="nucleotide sequence ID" value="XM_028672569.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUW7"/>
    <dbReference type="GeneID" id="39732051"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00352100"/>
    <dbReference type="OMA" id="HESAWDK"/>
    <dbReference type="OrthoDB" id="10265990at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.240:FF:000004">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit TIM44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039544">
        <property type="entry name" value="Tim44-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007379">
        <property type="entry name" value="Tim44-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10721">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10721:SF1">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04280">
        <property type="entry name" value="Tim44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00978">
        <property type="entry name" value="Tim44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Tim44-like" evidence="9">
        <location>
            <begin position="282"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="201"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="66"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG96303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="441" mass="52726" checksum="9B6138398310B689" modified="2017-02-15" version="1">MKNLLNNVISNFKFKSNLNFRRYFSGTYEKNIFTKNINGQNFRVYDENIIGRIIFSKDKKNFSTFMKNVIEQVKKDMKENKQYQEALKELKEKTEINDKTMKLKKKIEENINFYKNIKEKNVEAIKILYNDVHNFVKYCFENNYILKHSKNISIQFFSILKKFIINYSDKFIQLKERWNDNSAFIQLDKWRQEMAIKRYKKKNKQENEKINESDLSENDSEQKIENDMNINEKNSEQKENNELILAYESAWDKFGSKLKDMPFLNNFFENPFIGKLFGETELAAALREMKMYDKNFKLSELMYLFEYVISKHIVESYLIGDEETLRLHCGSSAFNSLNASINERKKKKVYLDTNVLIYKNHELKGAQRMEESSPWFIFTFHTQQINCLKNKNDEIIEGKIDDIREVVYTIALSKHPEPEKEGLLYPYIVREFAIIGNTPSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUX9</accession>
    <name>A0A1J1GUX9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00224600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527664.1">
        <property type="nucleotide sequence ID" value="XM_028670963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUX9"/>
    <dbReference type="GeneID" id="39730773"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00224600"/>
    <dbReference type="OrthoDB" id="345964at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="343" mass="40692" checksum="5A7B170152B3A004" modified="2017-02-15" version="1">MECEYEKKKSFYEIVLTIKKKIEKYDLSKWENIIKPEDVSYNDYFEKLVKESNTECDDKEIKINERNVNIENENKKNTYEINKDFFDNLSNRDKFYFLLSIKDTMETSWLLAQKRLEGIKLEENSEFINVQELLNYSKKLSDTTCAPPECDNINDKIIHQEYYPNYHFLNFVNIEEIHLSKLFQLQKYSTVCFPPIITIEENDNLLIVSITCSTPTTTIFYKINEEIQEKIYDSDNKPKIPKRQKINIYAWSVKEGFIKSRVSCFSKTYNVKEDNSQNLLDNEASQFFPDSFKSDKTENENIMNKQSSNTNVFKNLGFLLSRKKEKKLETSSNEESFSSNEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUY0</accession>
    <name>A0A1J1GUY0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein phosphatase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00353700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529124.1">
        <property type="nucleotide sequence ID" value="XM_028672586.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUY0"/>
    <dbReference type="GeneID" id="39732067"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00353700"/>
    <dbReference type="OMA" id="WLCLYLE"/>
    <dbReference type="OrthoDB" id="6375174at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38745">
        <property type="entry name" value="PHOSPHATASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38745:SF2">
        <property type="entry name" value="TYROSINE SPECIFIC PROTEIN PHOSPHATASES DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="2">
        <location>
            <begin position="195"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="290" mass="34544" checksum="AC775ED8F27E65B6" modified="2017-02-15" version="1">MWSPLNDSEYTETSNKYTKKGFFHTLKKYKKFIYIFLGIFVIYILFIVYYEINEKNADKDIDCNVLNEECKNYTYPEFDPERLLIVDANIENNNFLLRSSVPIFNGIFSEELLLKEIKRVVEESNLVYKNNYSLYIISLLKNNQKEGCCYASEKCYVKEANVDNQLILGYRDKDPYDLKKEELMTKLKNLTWNTDDILNKIDSLYEKFLNMKNTIFVIHCRRGRDRTGEYVGAYRMIKKKQSFDSVMNANSEIGILRESFVKMQKWICLYLENVLNYPNMGCYDYRSGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUY8</accession>
    <name>A0A1J1GUY8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TFIIS central domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00354500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529132.1">
        <property type="nucleotide sequence ID" value="XM_028672595.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732075"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00354500"/>
    <dbReference type="OMA" id="YFFCFNC"/>
    <dbReference type="OrthoDB" id="1742074at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.30">
        <property type="entry name" value="Transcription elongation factor S-II, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003618">
        <property type="entry name" value="TFIIS_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036575">
        <property type="entry name" value="TFIIS_cen_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46942">
        <property type="entry name" value="Elongation factor TFIIS domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51321">
        <property type="entry name" value="TFIIS_CENTRAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TFIIS central" evidence="3">
        <location>
            <begin position="1033"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="172"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="795"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="853"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1002"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="178"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="864"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="887"/>
            <end position="898"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1286" mass="152740" checksum="3DE082551226E8A0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVG7</accession>
    <name>A0A1J1GVG7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00004700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528093.1">
        <property type="nucleotide sequence ID" value="XM_028671441.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVG7"/>
    <dbReference type="GeneID" id="39728569"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00004700"/>
    <dbReference type="OrthoDB" id="413777at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="121" mass="14747" checksum="155E96BFF06103AB" modified="2017-02-15" version="1">MAFMFKREGCYSKNRLSELFRKNKSFVNQLMYDMTSFHYENYMKQKIHKNIMKNYNGHFYFRSGIPVITPHIEQTNEFADHNNYTYNFKNIKRKYLKKVYDSYKHKVGGTDASVPIFFKHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVH3</accession>
    <name>A0A1J1GVH3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Syntaxin, Qa-SNARE family, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SYN5</name>
        <name evidence="10" type="ORF">PGAL8A_00244200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527856.1">
        <property type="nucleotide sequence ID" value="XM_028671178.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVH3"/>
    <dbReference type="GeneID" id="39730970"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00244200"/>
    <dbReference type="OMA" id="EHNHNVV"/>
    <dbReference type="OrthoDB" id="421009at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048278">
        <property type="term" value="P:vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15844">
        <property type="entry name" value="SNARE_syntaxin5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF3">
        <property type="entry name" value="SYNTAXIN-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="262"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="9">
        <location>
            <begin position="190"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG95043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="281" mass="32783" checksum="0FE4155C409A0968" modified="2017-02-15" version="1">MPHVDKTEVFFKIVEKLSSDNFNLRKNRSIAQDTQVSELASKITNLLQGGNQKLQQLDRCVKQKGIFNDKTSEIEELTYEVKQTITDVTNNLDLLVNYTYSLNISNPQSRTHIDNIISSLKNQLYEFTKKFKDTLQIRSEHIKKQVNRRKMYSHTLTEATFNNENYKFTPLHDIDIESGQQQTLKVKEKTSYLHSRVDAMENIQKVIGDLAQMFQKVATMVTQQDEMIKRIDEDIDISLSNTREGQNYLLSYFNRVTSTRTLILQVFVCIFVLIVFFVLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVK1</accession>
    <name>A0A1J1GVK1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Spermidine synthase, putative</fullName>
            <ecNumber evidence="6">2.5.1.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00355800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the spermidine/spermine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.16" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529145.1">
        <property type="nucleotide sequence ID" value="XM_028672609.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVK1"/>
    <dbReference type="GeneID" id="39732088"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00355800"/>
    <dbReference type="OMA" id="FLYHEMM"/>
    <dbReference type="OrthoDB" id="38125at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004766">
        <property type="term" value="F:spermidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.140.10:FF:000012">
        <property type="entry name" value="Spermidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000190">
        <property type="entry name" value="Spermidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.140.10">
        <property type="entry name" value="Spermidine synthase, tetramerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00198">
        <property type="entry name" value="Spermidine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030374">
        <property type="entry name" value="PABS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030373">
        <property type="entry name" value="PABS_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001045">
        <property type="entry name" value="Spermi_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035246">
        <property type="entry name" value="Spermidine_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037163">
        <property type="entry name" value="Spermidine_synt_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF037959">
        <property type="entry name" value="MFS_SpdSyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002010">
        <property type="entry name" value="PRK00811.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00417">
        <property type="entry name" value="speE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11558:SF11">
        <property type="entry name" value="SPERMIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11558">
        <property type="entry name" value="SPERMIDINE/SPERMINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17284">
        <property type="entry name" value="Spermine_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01564">
        <property type="entry name" value="Spermine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01330">
        <property type="entry name" value="PABS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51006">
        <property type="entry name" value="PABS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PABS" evidence="5">
        <location>
            <begin position="40"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="320" mass="36790" checksum="2FC2DA440E409EC1" modified="2017-02-15" version="1">MEKISNNKTKLALALLGGLCSYAFYHLRKKFNFSYILFSKKWFSEYSLMWPGQAFSLEIKKIIYQTKSKLQNILVFESKTFGNVLVLDGVIQLTEKDEFSYHEMMTHIPMTVYEDAKNVLVVGGGDGGIIRELCKYKCVENIDICEIDEKVIEVSKKYFKNISCGFNDKRVHIFIEDASKFLEDITNTYDVIIIDSSDPIGPAETLFNQSFYEKVYNALKPNGVCVAQCESIWIHVGTIKKMMSFTKKIFKKVEYANISIPTYPCGCIGILCCSKRDTGLMKPIKKLDSKEFEDLKYYSYENHIASFKLPIFVLKEIENA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVK5</accession>
    <name>A0A1J1GVK5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00372300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529303.1">
        <property type="nucleotide sequence ID" value="XM_028672785.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVK5"/>
    <dbReference type="GeneID" id="39732253"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00372300"/>
    <dbReference type="OMA" id="KYNINIM"/>
    <dbReference type="OrthoDB" id="372030at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="233"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="240"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="545" mass="64711" checksum="70D12ACD692532BE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVW9</accession>
    <name>A0A1J1GVW9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">BSD-domain protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00427800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529502.1">
        <property type="nucleotide sequence ID" value="XM_028673006.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVW9"/>
    <dbReference type="GeneID" id="39732810"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00427800"/>
    <dbReference type="OMA" id="KEYENCY"/>
    <dbReference type="OrthoDB" id="382589at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3970.10">
        <property type="entry name" value="BSD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005607">
        <property type="entry name" value="BSD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035925">
        <property type="entry name" value="BSD_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03909">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00751">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140383">
        <property type="entry name" value="BSD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50858">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BSD" evidence="1">
        <location>
            <begin position="184"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="822" mass="96719" checksum="E6DFC49BDAE8F4BF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW15</accession>
    <name>A0A1J1GW15_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00367900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529259.1">
        <property type="nucleotide sequence ID" value="XM_028672736.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW15"/>
    <dbReference type="GeneID" id="39732209"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00367900"/>
    <dbReference type="OMA" id="PYQMFNG"/>
    <dbReference type="OrthoDB" id="368942at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="168" mass="18843" checksum="84C721277313E551" modified="2017-02-15" version="1">MQSTETQNLKATPNDGNEENVYDKDTHINSSQDNNYNEATQNLGKTNPIEGYYTVTHENNSPMGVNNIQYMTPSINESGIPVDPTAMQAAAAINQSLMFQNNGVPTDYPQYHMFNGMNTMYGGIPQYYGGLHMPMNPYYDPYGIINPLSCAPLNLEKTKKKTKKFYCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWB4</accession>
    <name>A0A1J1GWB4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 subunit 5, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00431100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529535.1">
        <property type="nucleotide sequence ID" value="XM_028673042.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWB4"/>
    <dbReference type="GeneID" id="39732843"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00431100"/>
    <dbReference type="OMA" id="EYFVHFH"/>
    <dbReference type="OrthoDB" id="25498at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071541">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex, eIF3m"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08064">
        <property type="entry name" value="MPN_eIF3f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027531">
        <property type="entry name" value="eIF3f"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024969">
        <property type="entry name" value="EIF3F/CSN6-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540:SF6">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13012">
        <property type="entry name" value="MitMem_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MPN" evidence="4">
        <location>
            <begin position="33"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="320" mass="36731" checksum="CC02A9BF261A3BCD" modified="2017-02-15" version="1">MSLNRYNFKTLSGLFKDKIPQHFDILPHTSIKCVIHPSVIFTILDAYLRRDEDQTHVIGTLMGSVIDTNLIEISDCFVDKHSLNEGGFLQIIKDHHETMYELKQKIRPRDQVVGWFCSGSELSELSCAVHGWFKEHNSISKFYPHSPLNEPIHLLVDAALESGFLNIKAFVQLPISLVKEYFVHFHEIQTELLPCNVERAEVLPYKEKLTVNKDKDNNNNANNAEIITNEMNEISLKKLLIMLKQCKSYVQDVIDKKKKGNLSVGRYLHKVLSNDTFLSLEKFDSLNENILQDNLMISYLSNLANLQFLIAEKLNASSLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWC8</accession>
    <name>A0A1J1GWC8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00435700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529578.1">
        <property type="nucleotide sequence ID" value="XM_028673091.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732889"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00435700"/>
    <dbReference type="OMA" id="CESYKPC"/>
    <dbReference type="OrthoDB" id="372379at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="626"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="664"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1074"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2189"/>
            <end position="2230"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2466"/>
            <end position="2494"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2857"/>
            <end position="2910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1074"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2189"/>
            <end position="2220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3687" mass="447195" checksum="F0A4FB83A63AA58E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWI3</accession>
    <name>A0A1J1GWI3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00449600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000074">
        <property type="protein sequence ID" value="CRG96915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529718.1">
        <property type="nucleotide sequence ID" value="XM_028673246.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWI3"/>
    <dbReference type="GeneID" id="39733029"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00449600"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="255" mass="30119" checksum="6158B7AC278F98AB" modified="2017-02-15" version="1">MKTLTLYLKITTFLLLIWMYQCFYNCNYYKTLIDKNTLQTKHELKYERVLTEGDIAGKIQTYSEGCLEQCPLDNKKNKCNNPVQYKNQCDPTHGVKTPSLWENFDKKAKEMDSNLRDHEFNIKWNDVSRDNVINVSSKIYQRNIPGEGRQILILSDTKDHSNLKKLLDECKKEIRDNKTESESMKEMRNNKTESESKEEMREYITFSEYMKETRENRTESESMKEIGDNKTESESKNDMGDNKTESESKNDLLNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWQ2</accession>
    <name>A0A1J1GWQ2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Proteasome subunit beta type-6, putative</fullName>
            <ecNumber evidence="4">3.4.25.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00444900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.25.1" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529671.1">
        <property type="nucleotide sequence ID" value="XM_028673193.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWQ2"/>
    <dbReference type="GeneID" id="39732982"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00444900"/>
    <dbReference type="OMA" id="TFIYGYC"/>
    <dbReference type="OrthoDB" id="7854943at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005839">
        <property type="term" value="C:proteasome core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF0">
        <property type="entry name" value="ATP-DEPENDENT PROTEASE SUBUNIT HSLV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-0647">Proteasome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="281" mass="32374" checksum="C8AAD9E84806929B" modified="2017-02-15" version="1">MMELENIKMQSVNENLDFANCIYDIKKPISDGTTIIGIIYDHGVMLACDTRTSSGTFISNKCSRKINRINENIYVCRSGASAHSQKVIEIIKHYCLAMKSENRKKGRFHENDSISEDINSEDIDIDKINNTNNKNNTDLITKNKYFYNDKFMDYNPLVENVAYITKKLVYANNNFLSCGLIFGGYDKEKKQQLYSVNLNGSIIRRFDFAVSGSGSIYIQSYLQDKYKKNMNKKECFDLILNCVKYAMYNDNSSGGIVRIVNITKLYVEEFTVTNTQLHFDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWQ6</accession>
    <name>A0A1J1GWQ6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NudC domain-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00433000</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529553.1">
        <property type="nucleotide sequence ID" value="XM_028673062.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWQ6"/>
    <dbReference type="GeneID" id="39732862"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00433000"/>
    <dbReference type="OMA" id="PKADWIF"/>
    <dbReference type="OrthoDB" id="428655at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd06467">
        <property type="entry name" value="p23_NUDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037895">
        <property type="entry name" value="NUDCD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21664">
        <property type="entry name" value="CHRONIC MYELOGENOUS LEUKEMIA TUMOR ANTIGEN 66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21664:SF1">
        <property type="entry name" value="NUDC DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013266800" description="NudC domain-containing protein 1" evidence="7">
        <location>
            <begin position="21"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="domain" description="CS" evidence="8">
        <location>
            <begin position="69"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="354"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="547"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="355"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="373"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="560"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG96749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="938" mass="111740" checksum="2EE1DCA4FB62243F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWT9</accession>
    <name>A0A1J1GWT9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipase, putative</fullName>
            <ecNumber evidence="3">3.1.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00298500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.3" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528581.1">
        <property type="nucleotide sequence ID" value="XM_028671983.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWT9"/>
    <dbReference type="GeneID" id="39731518"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00298500"/>
    <dbReference type="OrthoDB" id="426718at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004806">
        <property type="term" value="F:triacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051218">
        <property type="entry name" value="Sec_MonoDiacylglyc_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856:SF11">
        <property type="entry name" value="FUNGAL LIPASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="2">
        <location>
            <begin position="610"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="907" mass="108440" checksum="27800361390AE9E9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWZ4</accession>
    <name>A0A1J1GWZ4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00456300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529786.1">
        <property type="nucleotide sequence ID" value="XM_028673323.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733096"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00456300"/>
    <dbReference type="OMA" id="RILAMLF"/>
    <dbReference type="OrthoDB" id="10497857at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="8704"/>
            <end position="8723"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="8743"/>
            <end position="8761"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="8802"/>
            <end position="8821"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="8827"/>
            <end position="8845"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2074"/>
            <end position="2102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="4217"/>
            <end position="4243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="5225"/>
            <end position="5244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="6129"/>
            <end position="6150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="7545"/>
            <end position="7572"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="5662"/>
            <end position="5689"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="7213"/>
            <end position="7276"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="7390"/>
            <end position="7417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2077"/>
            <end position="2091"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="4221"/>
            <end position="4242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="5233"/>
            <end position="5243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="8956" mass="1083812" checksum="6B2F1F8FFC58216B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX29</accession>
    <name>A0A1J1GX29_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sphingomyelin phosphodiesterase, putative</fullName>
            <ecNumber evidence="2">3.1.4.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00460300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.12" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529826.1">
        <property type="nucleotide sequence ID" value="XM_028673367.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX29"/>
    <dbReference type="GeneID" id="39733136"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00460300"/>
    <dbReference type="OMA" id="YCRYIEN"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004767">
        <property type="term" value="F:sphingomyelin phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000300">
        <property type="entry name" value="IPPc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038772">
        <property type="entry name" value="Sph/SMPD2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16320:SF23">
        <property type="entry name" value="SPHINGOMYELINASE C 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16320">
        <property type="entry name" value="SPHINGOMYELINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22669">
        <property type="entry name" value="Exo_endo_phos2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inositol polyphosphate-related phosphatase" evidence="1">
        <location>
            <begin position="201"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="386" mass="45611" checksum="FE4E1731515D3AF1" modified="2017-02-15" version="1">MISLSTLEKGKLTIMSYNIQMLSIPFSIHLNSWMRRNAIIEYINVLDDLYNIDILVLNEVFTKKSYELLTSGEIKKRFPYHTNVVGKKCKSNECHDDILYNEEKDTLSYISRDSYKNEEDTCFIMQNENDNEINIQKEKLIKNIDNKNKKDISNNIEFSNFDTITGNAKFYQFFNGGVLVLSKHKILQKHALIYSCSTFPDMFCSKGAIYLKCEVNDKRINIIATHLQAGDKIKQQNSRMKQLNELSKWVYEGIPSHFIKKYEPLFFVGDLNIRYDVDKLYLEKVLSKTYLNSHVTKRSLETTFDSFLNDYCRYIENDYTYKYKYTLDYILVSNDSNIKIIVPQTAIQDNFRSLLFIKFFWGFIPYKTTYIHHPSDHFPIYATFQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXE9</accession>
    <name>A0A1J1GXE9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00450100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000076">
        <property type="protein sequence ID" value="CRG96920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529723.1">
        <property type="nucleotide sequence ID" value="XM_028673251.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXE9"/>
    <dbReference type="GeneID" id="39733034"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00450100"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="139" mass="16584" checksum="CA5F87CAEC51284B" modified="2017-02-15" version="1">MKTFTLYFKVFTFILLIWIFPFFYKYDSTKSLINRDTLQTKIGLKHERVLAEGDKSEKKSSSIEILIDRYPSNEIEMRHVDLVYLMDMYIKCYIANIVSNIVQEILFKKANEMRYKCGDKILNAYRNNYIEDPCEGFSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXV3</accession>
    <name>A0A1J1GXV3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Mitochondrial ribosomal protein S22, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00486400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Mitochondrial ribosome (mitoribosome) assembly factor. Binds at the interface of the head and body domains of the mitochondrial small ribosomal subunit (mt-SSU), occluding the mRNA channel and preventing compaction of the head domain towards the body. Probable inactive methyltransferase: retains the characteristic folding and ability to bind S-adenosyl-L-methionine, but it probably lost its methyltransferase activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530087.1">
        <property type="nucleotide sequence ID" value="XM_028673657.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXV3"/>
    <dbReference type="GeneID" id="39733397"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00486400"/>
    <dbReference type="OMA" id="GFRMIHS"/>
    <dbReference type="OrthoDB" id="421327at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052571">
        <property type="entry name" value="Mt_RNA_Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015324">
        <property type="entry name" value="Ribosomal_Rsm22-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13184">
        <property type="entry name" value="37S RIBOSOMAL PROTEIN S22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13184:SF5">
        <property type="entry name" value="METHYLTRANSFERASE-LIKE PROTEIN 17, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09243">
        <property type="entry name" value="Rsm22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00045681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="528" mass="62171" checksum="090865E4F645424D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXV4</accession>
    <name>A0A1J1GXV4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RAP protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00489100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530114.1">
        <property type="nucleotide sequence ID" value="XM_028673686.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXV4"/>
    <dbReference type="GeneID" id="39733424"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00489100"/>
    <dbReference type="OrthoDB" id="1608002at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013584">
        <property type="entry name" value="RAP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08373">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00952">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51286">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RAP" evidence="1">
        <location>
            <begin position="331"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="441" mass="53017" checksum="96D37C2D664EF5EC" modified="2017-02-15" version="1">MGLIRPRERVIINAIRRESRIKYKAKRMHKRFRSWAQQRVREYWLPMNVCLTSNVKLMDGQYISACVQKAATLRKHDYELWRRYSERILEISETLTPQQIGYIFYGMGKSKFLNTEFYDKFLTSVQNNLDSFYSHPLMCVAWSLNRVLIRKEEFFKEFCKIVINKFDDIRTKDLIKINTSIAKLSIHDKNYKNHINKNMINKLEVIFAQDFRNVINDVTLINLYDDEVKKYILTRFSNMFICARPQHYKNAYKSAVAVRVLFPHVWDSLTNKVKSFYVRLSMRRIPEISRKPSEFQWEVSDCLAKLGISHRNTFLWGCYFIDIGETNEKRNCWFIDGPTCFYTSTNQYTESVKLQHRILYDLGWNIRRIVWLDWIKFGNDINKKVEYVKYLREKEPLGKNLDHFPNISVDNIKNKLKELKLYKIQKEIEKTKNEPKIYLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYC7</accession>
    <name>A0A1J1GYC7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00322150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000049">
        <property type="protein sequence ID" value="CRG96008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528816.1">
        <property type="nucleotide sequence ID" value="XM_028672245.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYC7"/>
    <dbReference type="GeneID" id="39731754"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00322150"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="141" mass="16859" checksum="138288FCD34C74A5" modified="2017-02-15" version="1">MKTFTLYLEIFAFLLLIWIFPFFYNYDSSKSLINRDTLQAKIGLKHERMLAEADISEKKSSYIRKRVEEYPSGEMNIGNNELIHLMDMYLKCYNANSMATYVEVLFKVENEMRYKCRDKILNAYRNNISYEIEIEKLSLTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYK8</accession>
    <name>A0A1J1GYK8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA methyltransferase, putative</fullName>
            <ecNumber evidence="4">2.1.1.34</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00490000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.34" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530123.1">
        <property type="nucleotide sequence ID" value="XM_028673696.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYK8"/>
    <dbReference type="GeneID" id="39733433"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00490000"/>
    <dbReference type="OrthoDB" id="270651at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141100">
        <property type="term" value="F:tRNA (guanine(18)-2'-O)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18096">
        <property type="entry name" value="SpoU-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051259">
        <property type="entry name" value="rRNA_Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43191:SF7">
        <property type="entry name" value="OBP33PEP LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43191">
        <property type="entry name" value="RRNA METHYLTRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="tRNA/rRNA methyltransferase SpoU type" evidence="3">
        <location>
            <begin position="65"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="263" mass="30661" checksum="C6BF612BA39FA6FB" modified="2017-02-15" version="1">MDEFNEIEVTNENSDVYQNKDINKNEEINGKDEISKGDISIYNMKSKEVCENIMIKNNCDKKINMYVVIYNISKKKNVGSIIRSCVAFNVSKIFIIGRKKKEINFFGNMGTYQYISIEYFDNIIELKDYLKKNNILLYGCEITNNSISVTKKPFIKDTAFLFGNEGTGIEDKILNLCDKIIYIPQYGNGTSSLNVSISCSIILHNFAIWANYKEIEIENKKFIIQKNKNKLDNYLHPSDDLLKEINNKRLMRSEKKKDYNFFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYN7</accession>
    <name>A0A1J1GYN7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MINDY deubiquitinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00515400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530382.1">
        <property type="nucleotide sequence ID" value="XM_028673984.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYN7"/>
    <dbReference type="GeneID" id="39733687"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00515400"/>
    <dbReference type="OMA" id="CNYRKNI"/>
    <dbReference type="OrthoDB" id="10261212at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016807">
        <property type="term" value="F:cysteine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990380">
        <property type="term" value="F:K48-linked deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071108">
        <property type="term" value="P:protein K48-linked deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007518">
        <property type="entry name" value="MINDY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033979">
        <property type="entry name" value="MINDY_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18063">
        <property type="entry name" value="NF-E2 INDUCIBLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18063:SF6">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04424">
        <property type="entry name" value="MINDY_DUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MINDY deubiquitinase" evidence="1">
        <location>
            <begin position="53"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="590" mass="69883" checksum="567B88B5C9B21BB6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYP4</accession>
    <name>A0A1J1GYP4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00516200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530390.1">
        <property type="nucleotide sequence ID" value="XM_028673993.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYP4"/>
    <dbReference type="GeneID" id="39733695"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00516200"/>
    <dbReference type="OMA" id="DMFKDQN"/>
    <dbReference type="OrthoDB" id="384423at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1268" mass="152964" checksum="0C238FE0C23FD384" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYQ0</accession>
    <name>A0A1J1GYQ0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">histone acetyltransferase</fullName>
            <ecNumber evidence="1">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00526800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530493.1">
        <property type="nucleotide sequence ID" value="XM_028674107.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYQ0"/>
    <dbReference type="GeneID" id="39733801"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00526800"/>
    <dbReference type="OrthoDB" id="47374at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004596">
        <property type="term" value="F:protein-N-terminal amino-acid acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045141">
        <property type="entry name" value="NAA60-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14744">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14744:SF15">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="754"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="492"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="639"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="639"/>
            <end position="662"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1136" mass="134699" checksum="BE84FC4EAC05FFD5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYR1</accession>
    <name>A0A1J1GYR1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tetratricopeptide repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00336200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528952.1">
        <property type="nucleotide sequence ID" value="XM_028672395.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYR1"/>
    <dbReference type="GeneID" id="39731892"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00336200"/>
    <dbReference type="OMA" id="EHPLFMD"/>
    <dbReference type="OrthoDB" id="420195at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46035">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46035:SF1">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="426" mass="51134" checksum="2E4D8F879A373B5B" modified="2017-02-15" version="1">MEEDFNIDEDYIKKLSEKYKNVDHPLFMSELPKNIEENEDLEALYNLMISDENPISLAKNYKEVGNDYFKDGVKYYEDAIISYNKGIDILNSYINSINNDKLKKQNNLNHVTNKKYNNDEQIKLINENNCNNGCILDKDSNTMNEKKLKEECENNFITTNVSNNTNKNEAINLLSDIYCNKSIIHYKKKRYVKCLDDCKKALSYNNKKYKCLYFCALCSYHMELYNDAYKYIKIFDDLIKDENIRSLININDYEKLKNQILEKYENFLHRKKIKEDEKKIIIEKQKNEMNKIENILRKRDITILENIYNNDNITPVLYLDENRYIHFTVFLIYFETNFIDTILDFAENTRIIDYFDIIKKNKENELLFCYLEFPDDKFYFINKYSYICDIINKIKLFTPIISLHIIENADANNTFKSNKNIFFIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYS8</accession>
    <name>A0A1J1GYS8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-i protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00376600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000097">
        <property type="protein sequence ID" value="CRG97393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530195.1">
        <property type="nucleotide sequence ID" value="XM_028673776.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYS8"/>
    <dbReference type="GeneID" id="39732296"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00376600"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="119"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="216" mass="25852" checksum="2972589ECC28E6E9" modified="2017-02-15" version="1">MDLNLSDIIYIDSCETLDEEDSTAGFAHREIKDATVSIPENPLHDDLNSCDAIQNPSKDINLDSATSINVLHKKSYNIFQLAIIIISILRFRARTTKWKAKRERDRLQKIWDNSSKEMKGDFEKKMLEEKEKMEEREKKLLKKKKKIEEEEKRILREKEMWEKRTLKKKKECDKNKLKELEEWEKLIIKKGENWKKEMIIEKIKLENEISENKLCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ06</accession>
    <name>A0A1J1GZ06_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00511600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530344.1">
        <property type="nucleotide sequence ID" value="XM_028673941.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ06"/>
    <dbReference type="GeneID" id="39733649"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00511600"/>
    <dbReference type="OMA" id="DHISGMD"/>
    <dbReference type="OrthoDB" id="369618at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="452" mass="53687" checksum="796622AD34647F0B" modified="2017-02-15" version="1">MNVNINHQYDIRNLQEQREYADYNFYDYPKNFDMLDQNNKFNNPLNSSYYKQREINVPSINLKSRSSHINTNNELMRESNNFLNVVPISSKDIEYYEYVNPPINLNEENYYNHYEVNNNIIPTDGVKYEMNNEINRTQLIHNLSDKLNNSYANLNNGNYVNEEIIHNEINNYREPNHINNSFDYLNYNMNNMNSNYIVENYNSVLSNNIKNIPFNSIHNNNFNNENYNLLNMDNSPMLFSKNTQEFNENEMNFSKLKNINLSKNITNTLDQLQAIVCLQKLEEIPAPFLNINEIKYSVSVYFNSYDDIINKYQSKFYNCKLNESYTYADCDLQNEIISLPFNNEEFIYLKVIETSVYKTEITGRLQLKVKSLSQEYPLRIPIIGDDGNSKGFLIMNFFITSSYYDVKNDILTEKSTLPNRTKSTRIRRKNNGFHFFENFTKWCCEITDDHIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ54</accession>
    <name>A0A1J1GZ54_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00351700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529104.1">
        <property type="nucleotide sequence ID" value="XM_028672564.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ54"/>
    <dbReference type="GeneID" id="39732047"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00351700"/>
    <dbReference type="OMA" id="SEHWIDP"/>
    <dbReference type="OrthoDB" id="332524at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="271" mass="32246" checksum="8EABDF72256F5DE7" modified="2017-02-15" version="1">MIRILIIFVFIIFIFKLNVNFILIKNKKKFSLFIINKNKWNTKNKKIKKNLKTYLWGYPIYDDSPNKLRRPKIYPNFEYGELRKGQDFDYVISTNISQNNYKIPDVGYLFKVDEMGTGKMDDVHTPIEMVFGEKDIDMKEVDKIKKVLNIFDQGNGLGICTLMGAKRAHFAFKYNGYLNHFYGIKNYLRFLINKHYPGAKVTLISEHWIDSIDKPVCIRHSNIPFSKIGYQRRLIFGKYDYIYENDKNKRIYKGENKSNVWAFYDDPQMLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZC4</accession>
    <name>A0A1J1GZC4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00035400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530717.1">
        <property type="nucleotide sequence ID" value="XM_028674356.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZC4"/>
    <dbReference type="GeneID" id="39728878"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00035400"/>
    <dbReference type="OMA" id="EYHTNIN"/>
    <dbReference type="OrthoDB" id="345965at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="238" mass="28621" checksum="4149443A2C4CEDC9" modified="2017-02-15" version="1">MDKETFLLNEQIKFDKFNENVEEEYKRKFNSDSKIDGYFEDDASSNLMLREKKKKEKIFLYNFISPFIDLGKHFYSSLKLIYEPKLYHLSIFLTMLWGYKNIKCINKLLFYKYNDIYYQITRPDSLNSRNKAFKTLVIGGLVIPCSFVAFSIYDMSKEKKNSLFIKNFEKPLSEKKTIIIPYNLRRNISKKVLSLKEKTLFFAKDLAENNNFKRLSKEYHKNINKRLNKNYLKKDELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZG0</accession>
    <name>A0A1J1GZG0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00041900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG97990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530787.1">
        <property type="nucleotide sequence ID" value="XM_028674435.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZG0"/>
    <dbReference type="GeneID" id="39728944"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00041900"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="178" mass="21657" checksum="D99E8093B5CC4634" modified="2017-02-15" version="1">MKTLTLYLKITTFLLFIWIYQCFFKCDPYKSLIDKNTLKTKNELKYERVLTEGNISGKEQTYAKECIEESPLDDKKNKWENPNLYKDPYKYWYSVITTKLWERFDKETSGMSPNSKNRKWNVEWHKISTEKAKELYFVNLRRYIPYEEKKKIIDSVIEELDSKFETFLCECKKGDRKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZG1</accession>
    <name>A0A1J1GZG1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Zinc finger protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00039500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530757.1">
        <property type="nucleotide sequence ID" value="XM_028674400.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZG1"/>
    <dbReference type="GeneID" id="39728919"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00039500"/>
    <dbReference type="OMA" id="FRDSEEW"/>
    <dbReference type="OrthoDB" id="153872at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19821">
        <property type="entry name" value="Bbox1_BBX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19756">
        <property type="entry name" value="Bbox2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049808">
        <property type="entry name" value="CONSTANS-like_Bbox1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000315">
        <property type="entry name" value="Znf_B-box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31717">
        <property type="entry name" value="ZINC FINGER PROTEIN CONSTANS-LIKE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31717:SF45">
        <property type="entry name" value="ZINC FINGER PROTEIN CONSTANS-LIKE 14-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00643">
        <property type="entry name" value="zf-B_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00336">
        <property type="entry name" value="BBOX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56399">
        <property type="entry name" value="ADP-ribosylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57845">
        <property type="entry name" value="B-box zinc-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50119">
        <property type="entry name" value="ZF_BBOX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="B box-type" evidence="5">
        <location>
            <begin position="283"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="B box-type" evidence="5">
        <location>
            <begin position="336"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="404"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="549" mass="63854" checksum="F54610790981B1F6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZI0</accession>
    <name>A0A1J1GZI0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RAP protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00520900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530434.1">
        <property type="nucleotide sequence ID" value="XM_028674041.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZI0"/>
    <dbReference type="GeneID" id="39733742"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00520900"/>
    <dbReference type="OMA" id="CADIMLP"/>
    <dbReference type="OrthoDB" id="385235at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013584">
        <property type="entry name" value="RAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058917">
        <property type="entry name" value="RESC6_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08373">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26188">
        <property type="entry name" value="RESC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00952">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51286">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RAP" evidence="2">
        <location>
            <begin position="756"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="251"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="922" mass="110012" checksum="2204B687EEE147CE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZK1</accession>
    <name>A0A1J1GZK1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00043100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530797.1">
        <property type="nucleotide sequence ID" value="XM_028674446.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728956"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00043100"/>
    <dbReference type="OMA" id="DFFQYKH"/>
    <dbReference type="OrthoDB" id="377675at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="754"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1526"/>
            <end position="1553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1653" mass="198949" checksum="26CC39F9E67A89C5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZV4</accession>
    <name>A0A1J1GZV4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">AAA family ATPase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00058500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530947.1">
        <property type="nucleotide sequence ID" value="XM_028674612.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZV4"/>
    <dbReference type="GeneID" id="39729110"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00058500"/>
    <dbReference type="OMA" id="NTSYKCV"/>
    <dbReference type="OrthoDB" id="10251136at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001054">
        <property type="entry name" value="ATPase, AAA family, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050304">
        <property type="entry name" value="MT-severing_AAA_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074">
        <property type="entry name" value="AAA DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074:SF17">
        <property type="entry name" value="FIDGETIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="8">
        <location>
            <begin position="356"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="254"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="267"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG98150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="600" mass="69863" checksum="BE8BC4A7FE6402DC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZZ3</accession>
    <name>A0A1J1GZZ3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Signal peptidase complex subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00416900</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SPCS3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529392.1">
        <property type="nucleotide sequence ID" value="XM_028672884.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZZ3"/>
    <dbReference type="GeneID" id="39732700"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00416900"/>
    <dbReference type="OMA" id="FWDDGHG"/>
    <dbReference type="OrthoDB" id="10261524at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005787">
        <property type="term" value="C:signal peptidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045047">
        <property type="term" value="P:protein targeting to ER"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007653">
        <property type="entry name" value="SPC3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12804">
        <property type="entry name" value="MICROSOMAL SIGNAL PEPTIDASE 23 KD SUBUNIT SPC22/23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12804:SF0">
        <property type="entry name" value="SIGNAL PEPTIDASE COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04573">
        <property type="entry name" value="SPC22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016089">
        <property type="entry name" value="SPC22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG96588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="186" mass="22522" checksum="0F7593C0A738291B" modified="2017-02-15" version="1">MDSFLNRLNVIFYSMALCFFILCLFNYGTSFYLFDEKEIKTHIKVNNVKRFIYNRYIKGDEVVLSLDLSYDMRKAFNWNLKQLFVYVLVTYETPKKVRNEVIIQDYIITKKKKNTKKNYKNFITKYSLKDYSNGLRNNLIHLQVCYKYMPIVGFTRSFEGHKISYKLPSEYFDNLPSNYPFYYPDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H036</accession>
    <name>A0A1J1H036_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00422400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529448.1">
        <property type="nucleotide sequence ID" value="XM_028672946.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H036"/>
    <dbReference type="GeneID" id="39732756"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00422400"/>
    <dbReference type="OMA" id="NYFAVIN"/>
    <dbReference type="OrthoDB" id="391686at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009618950" evidence="1">
        <location>
            <begin position="25"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="550" mass="65924" checksum="758E6FC704D6C800" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H338</accession>
    <name>A0A1J1H338_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Symplekin C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00532800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530551.1">
        <property type="nucleotide sequence ID" value="XM_028674171.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733861"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00532800"/>
    <dbReference type="OrthoDB" id="331600at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048018">
        <property type="term" value="F:receptor ligand activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022075">
        <property type="entry name" value="Symplekin_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37458">
        <property type="entry name" value="THISBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37458:SF1">
        <property type="entry name" value="THISBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12295">
        <property type="entry name" value="Symplekin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1423"/>
            <end position="1442"/>
        </location>
    </feature>
    <feature type="domain" description="Symplekin C-terminal" evidence="3">
        <location>
            <begin position="1882"/>
            <end position="2095"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="672"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1060"/>
            <end position="1109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1780"/>
            <end position="1826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1060"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1094"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1784"/>
            <end position="1826"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2131" mass="255966" checksum="1D981671E4862425" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3U6</accession>
    <name>A0A1J1H3U6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fam-a protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00059400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530956.1">
        <property type="nucleotide sequence ID" value="XM_028674622.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3U6"/>
    <dbReference type="GeneID" id="39729119"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00059400"/>
    <dbReference type="OrthoDB" id="377386at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009618959" description="Fam-a protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="316" mass="37356" checksum="98F3526FAEC29E3B" modified="2017-02-15" version="1">MKNFFNFLFLSIFIIKIQNICAITTNEIIKNKRINFLNEARNIINQSNLVDQNEKIMDDSLRTYKYYMLKDKTEIRAIFIFDDLNINKAKKLGIYDQKHKIDILDIQNRVHNLFPLDGISSLTDVLYKERQTFSFNTDYAITNYVFSRFVFNINVHEKNDEEIMSLLLDNELIMKKKNLIIKKNNNGYEANDSIERYTQNSNNLLKNHPHSFSQFIGALLNISSIVTSISGTISAISSLFSNEPSPSPPKFLGEEKAPLLTHVERKTILNKSENKSHHSYRKNNKEYEDEYEDEDEYEEEYEDEYEDEDEDEYDYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3Y0</accession>
    <name>A0A1J1H3Y0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cg1 protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00049300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530855.1">
        <property type="nucleotide sequence ID" value="XM_028674509.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3Y0"/>
    <dbReference type="GeneID" id="39729018"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00049300"/>
    <dbReference type="OMA" id="YEVCLPN"/>
    <dbReference type="OrthoDB" id="448954at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.390">
        <property type="entry name" value="Hemimethylated DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011722">
        <property type="entry name" value="Hemimethylated_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036623">
        <property type="entry name" value="Hemimethylated_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08755">
        <property type="entry name" value="YccV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00992">
        <property type="entry name" value="YccV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141255">
        <property type="entry name" value="YccV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013040428" evidence="1">
        <location>
            <begin position="17"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="domain" description="Hemimethylated DNA-binding" evidence="2">
        <location>
            <begin position="786"/>
            <end position="928"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="946" mass="113196" checksum="0DFF5D04CDC94B26" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKW1</accession>
    <name>A0A1J1GKW1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AP complex subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00075400</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525870.1">
        <property type="nucleotide sequence ID" value="XM_028675156.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKW1"/>
    <dbReference type="GeneID" id="39729279"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00075400"/>
    <dbReference type="OMA" id="PECNEWG"/>
    <dbReference type="OrthoDB" id="10254310at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030131">
        <property type="term" value="C:clathrin adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030276">
        <property type="term" value="F:clathrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000002">
        <property type="entry name" value="AP complex subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1150:FF:000002">
        <property type="entry name" value="Beta-adaptin-like protein C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="entry name" value="TATA-Binding Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026739">
        <property type="entry name" value="AP_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016342">
        <property type="entry name" value="AP_complex_bsu_1_2_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015151">
        <property type="entry name" value="B-adaptin_app_sub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013041">
        <property type="entry name" value="Clathrin_app_Ig-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013037">
        <property type="entry name" value="Clathrin_b-adaptin_app_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009028">
        <property type="entry name" value="Coatomer/calthrin_app_sub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11134">
        <property type="entry name" value="ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09066">
        <property type="entry name" value="B2-adapt-app_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002291">
        <property type="entry name" value="AP_complex_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01020">
        <property type="entry name" value="B2-adapt-app_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49348">
        <property type="entry name" value="Clathrin adaptor appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55711">
        <property type="entry name" value="Subdomain of clathrin and coatomer appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Beta-adaptin appendage C-terminal subdomain" evidence="8">
        <location>
            <begin position="805"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="589"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="597"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="622"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="922" mass="105034" checksum="6C24AF5989FDF32D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL83</accession>
    <name>A0A1J1GL83_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">50S ribosomal protein L10, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00087200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525990.1">
        <property type="nucleotide sequence ID" value="XM_028671244.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL83"/>
    <dbReference type="GeneID" id="39729396"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00087200"/>
    <dbReference type="OrthoDB" id="360689at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05797">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_uL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_uL10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047865">
        <property type="entry name" value="Ribosomal_uL10_bac_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11560">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="Ribosomal protein L10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="273" mass="32291" checksum="1F4960D95C872286" modified="2017-02-15" version="1">MFIKKIKTKYILFLLLLYFIYDIFTDYSKKFENYNIYKKSLIISASSIKKKGTLLRTKDIICFLKGVFIKNSIEKKKICKNINFSLKSRKCDGYRNTREGKEETVRKVRRILKVTKLLIQLNSFKLTPNLRMDLLINMPRPHVRMHMVKNTLMKISVKNTPFEAITPYLKESNVYLFIMNENYISFTLYSNKMFGSLYKDYKLNNFIKLSVYENTVLDKKETEDLINLKSYNVYFGHIINKINKTITNIPNSILQIPSSIARGIYLNTQKNNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLG7</accession>
    <name>A0A1J1GLG7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00087500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525993.1">
        <property type="nucleotide sequence ID" value="XM_028671277.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729399"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00087500"/>
    <dbReference type="OrthoDB" id="370629at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012068584" evidence="3">
        <location>
            <begin position="24"/>
            <end position="1443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="274"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="302"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="441"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="1">
        <location>
            <begin position="659"/>
            <end position="693"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1443" mass="172339" checksum="B306F499B0153D1C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLJ2</accession>
    <name>A0A1J1GLJ2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histone acetyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">HAT1</name>
        <name evidence="9" type="ORF">PGAL8A_00089900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-lysyl-[protein] + acetyl-CoA = N(6)-acetyl-L-lysyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:45948"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10731"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="2.3.1.48"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the HAT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526017.1">
        <property type="nucleotide sequence ID" value="XM_028671544.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLJ2"/>
    <dbReference type="GeneID" id="39729423"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00089900"/>
    <dbReference type="OrthoDB" id="10253098at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031509">
        <property type="term" value="P:subtelomeric heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.360.10">
        <property type="entry name" value="Histone acetyl transferase 1 (HAT1), N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019467">
        <property type="entry name" value="Hat1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037113">
        <property type="entry name" value="Hat1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017380">
        <property type="entry name" value="Hist_AcTrfase_B-typ_cat-su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12046">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE TYPE B CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10394">
        <property type="entry name" value="Hat1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histone acetyl transferase HAT1 N-terminal" evidence="8">
        <location>
            <begin position="57"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="592"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="641"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="749"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="266"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="592"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="643"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="669"/>
            <end position="697"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1031" mass="122765" checksum="C99D6A74160EB6A9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLT3</accession>
    <name>A0A1J1GLT3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">25S rRNA (uridine-N(3))-methyltransferase BMT5-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00088500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526003.1">
        <property type="nucleotide sequence ID" value="XM_028671388.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLT3"/>
    <dbReference type="GeneID" id="39729409"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00088500"/>
    <dbReference type="OrthoDB" id="273345at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070042">
        <property type="term" value="F:rRNA (uridine-N3-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019446">
        <property type="entry name" value="BMT5-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10354">
        <property type="entry name" value="BMT5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="25S rRNA (uridine-N(3))-methyltransferase BMT5-like" evidence="1">
        <location>
            <begin position="116"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="341" mass="40797" checksum="2D18A5573A5BBB97" modified="2017-02-15" version="1">MNSPFFKKKCRLINIFKLHFANFNSSYKLSEIKKEYGAFEKLLFLGNYEVEKYMNKELIKKYKECIKNDYNKLKNMLYEKECKSVYEKYLYDCVRNNDYEDLIIGDVIYENKKKILCIGEANLSFSALLQKNLNICSVVATSMEDKLKLIKNYGNIFTKNLKVLEQCGGIYISNINVETIDKHFLKNTFDIIVFNFPFVLPTKELIEKKWKVKLDKEDNNYIKYYKKAEYFLFNKLFYYLFKNSSILLKEKGYLHLRINDKYLTCKFPNDFSMSFVQKIDFYNSFMIYKLLKYVPSIYDSSFTNSNINNLKKNKNVIYTPNGKIFKSFKMKHTSTLIFQKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLT6</accession>
    <name>A0A1J1GLT6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cyclase-associated protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CAP</name>
        <name evidence="4" type="ORF">PGAL8A_00101400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CAP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526130.1">
        <property type="nucleotide sequence ID" value="XM_028672799.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLT6"/>
    <dbReference type="GeneID" id="39729539"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00101400"/>
    <dbReference type="OrthoDB" id="1601at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008179">
        <property type="term" value="F:adenylate cyclase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019933">
        <property type="term" value="P:cAMP-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001837">
        <property type="entry name" value="Adenylate_cyclase-assoc_CAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013912">
        <property type="entry name" value="Adenylate_cyclase-assoc_CAP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017901">
        <property type="entry name" value="C-CAP_CF_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016098">
        <property type="entry name" value="CAP/MinC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036223">
        <property type="entry name" value="CAP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006599">
        <property type="entry name" value="CARP_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10652">
        <property type="entry name" value="ADENYLYL CYCLASE-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10652:SF0">
        <property type="entry name" value="ADENYLYL CYCLASE-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08603">
        <property type="entry name" value="CAP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00673">
        <property type="entry name" value="CARP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69340">
        <property type="entry name" value="C-terminal domain of adenylylcyclase associated protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51329">
        <property type="entry name" value="C_CAP_COFACTOR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C-CAP/cofactor C-like" evidence="3">
        <location>
            <begin position="87"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="53"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="53"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="254" mass="29540" checksum="D0AB3503A1D24BD7" modified="2017-02-15" version="1">MAIFSCCTEVQLAKDNYHIKKFNEKKLNNDNKIKKEKLNNNDIKKKINNEKERKIDDKVKDKTSNNSKNNKFKQKKSEFKNKKRNFPKNQENMTSESVLELKDNQWNVSNFKNSGTVKLNEVELNNAVNIFNSENTTFVIENDKFKSLQIQKCVKCNIVLNNLISSIEIIDSKKIKVQALGKCSSITIDKCVGVDIYLSKENTETEFTTALSAEMNIHLENEDNDWNEITIPEQFQHQLENGKLNTRVSDLYKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLU7</accession>
    <name>A0A1J1GLU7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">rRNA-processing protein FCF1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">FCF1</name>
        <name evidence="7" type="ORF">PGAL8A_00111400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the UTP23/FCF1 family. FCF1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526230.1">
        <property type="nucleotide sequence ID" value="XM_028673910.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLU7"/>
    <dbReference type="GeneID" id="39729639"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00111400"/>
    <dbReference type="OMA" id="PECVFAE"/>
    <dbReference type="OrthoDB" id="76105at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09864">
        <property type="entry name" value="PIN_Fcf1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1010:FF:000039">
        <property type="entry name" value="rRNA-processing protein FCF1 family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006984">
        <property type="entry name" value="Fcf1/UTP23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037503">
        <property type="entry name" value="Fcf1_PIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12416">
        <property type="entry name" value="RRNA-PROCESSING PROTEIN UTP23 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04900">
        <property type="entry name" value="Fcf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00670">
        <property type="entry name" value="PINc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="PIN" evidence="6">
        <location>
            <begin position="64"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="193" mass="22572" checksum="2CDAAB51E900468C" modified="2017-02-15" version="1">MGKFKKTQKILKLKRVINPNDNRLKQCNDKKIKKKNKNEEKIKQVEVIDSNLFFNYNENLTPPYNIILDTNFINSSIQYKIDIVKGCSELLLAKCNIFVTDCVMAEMEKLGQRYSLALKLLKDARFNRLTCTHKGTYADDCIVNRVTESRCYIIATNDRDLKIRLRKIPGVPILYAKNFKYKIERLPDNIMIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLY5</accession>
    <name>A0A1J1GLY5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00106900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526186.1">
        <property type="nucleotide sequence ID" value="XM_028673422.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLY5"/>
    <dbReference type="GeneID" id="39729595"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00106900"/>
    <dbReference type="OMA" id="NTKVCYL"/>
    <dbReference type="OrthoDB" id="368420at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="97" mass="11822" checksum="3A16A55F63A2043D" modified="2017-02-15" version="1">MENNKIIKLKNNLNTFEMFMNQYIVKYKNSKVCYLCKNKIKNNHIEKMENICPKMWKYFHGIINQPQCPLQSFGKVLKVKDLRFEELEIYKDSLQRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM17</accession>
    <name>A0A1J1GM17_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00113900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526255.1">
        <property type="nucleotide sequence ID" value="XM_028674187.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729664"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00113900"/>
    <dbReference type="OMA" id="YHHLLYH"/>
    <dbReference type="OrthoDB" id="392876at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="396"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="888"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1392"/>
            <end position="1409"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="623"/>
            <end position="650"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1434" mass="173959" checksum="3FB14BECD32B75D9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM34</accession>
    <name>A0A1J1GM34_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Translation initiation factor IF-2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">IF2c</name>
        <name evidence="7" type="ORF">PGAL8A_00120300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526318.1">
        <property type="nucleotide sequence ID" value="XM_028674715.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM34"/>
    <dbReference type="GeneID" id="39729728"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00120300"/>
    <dbReference type="OMA" id="GILKECK"/>
    <dbReference type="OrthoDB" id="361630at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01887">
        <property type="entry name" value="IF2_eIF5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000019">
        <property type="entry name" value="Translation initiation factor IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10050">
        <property type="entry name" value="Translation initiation factor IF- 2, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053905">
        <property type="entry name" value="EF-G-like_DII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015760">
        <property type="entry name" value="TIF_IF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023115">
        <property type="entry name" value="TIF_IF2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036925">
        <property type="entry name" value="TIF_IF2_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381:SF5">
        <property type="entry name" value="TR-TYPE G DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22042">
        <property type="entry name" value="EF-G_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11987">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52156">
        <property type="entry name" value="Initiation factor IF2/eIF5b, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="6">
        <location>
            <begin position="668"/>
            <end position="837"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1274" mass="149005" checksum="C95AE45E70439C4A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM49</accession>
    <name>A0A1J1GM49_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00120100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526316.1">
        <property type="nucleotide sequence ID" value="XM_028674713.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM49"/>
    <dbReference type="GeneID" id="39729726"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00120100"/>
    <dbReference type="OrthoDB" id="372486at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="499"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="616" mass="73206" checksum="1FD0BAEEF559BA2C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMY8</accession>
    <name>A0A1J1GMY8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Organic anion transporter, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00143000</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526546.1">
        <property type="nucleotide sequence ID" value="XM_028674968.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMY8"/>
    <dbReference type="GeneID" id="39729954"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00143000"/>
    <dbReference type="OMA" id="WTIIIGK"/>
    <dbReference type="OrthoDB" id="6770063at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06174">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044770">
        <property type="entry name" value="MFS_spinster-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23505:SF79">
        <property type="entry name" value="PROTEIN SPINSTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23505">
        <property type="entry name" value="SPINSTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="74"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="652"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="686"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="748"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="776"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="815"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="865"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="278"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="415"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="494"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="278"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="325"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="351"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="495"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="902" mass="104294" checksum="6910F763D9239D12" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN06</accession>
    <name>A0A1J1GN06_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00155000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526662.1">
        <property type="nucleotide sequence ID" value="XM_028675096.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN06"/>
    <dbReference type="GeneID" id="39730074"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00155000"/>
    <dbReference type="OMA" id="GTMQYNQ"/>
    <dbReference type="OrthoDB" id="264785at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32083:SF0">
        <property type="entry name" value="CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32083">
        <property type="entry name" value="CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="149"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="464"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="850"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="909" mass="108008" checksum="A430684583D007E9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN40</accession>
    <name>A0A1J1GN40_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">pyridoxal 5'-phosphate synthase (glutamine hydrolyzing)</fullName>
            <ecNumber evidence="3">4.3.3.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00149600</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>aldehydo-D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = pyridoxal 5'-phosphate + L-glutamate + phosphate + 3 H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:31507"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
            <dbReference type="EC" id="4.3.3.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; pyridoxal 5'-phosphate biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the PdxS/SNZ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.3.6" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526610.1">
        <property type="nucleotide sequence ID" value="XM_028675039.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN40"/>
    <dbReference type="GeneID" id="39730020"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00149600"/>
    <dbReference type="OMA" id="RYANRGW"/>
    <dbReference type="OrthoDB" id="1660966at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036381">
        <property type="term" value="F:pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042823">
        <property type="term" value="P:pyridoxal phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000001">
        <property type="entry name" value="Pyridoxine biosynthesis protein PDX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001852">
        <property type="entry name" value="PdxS/SNZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033755">
        <property type="entry name" value="PdxS/SNZ_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003215">
        <property type="entry name" value="PRK04180.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31829">
        <property type="entry name" value="PYRIDOXAL 5'-PHOSPHATE SYNTHASE SUBUNIT SNZ1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31829:SF0">
        <property type="entry name" value="PYRIDOXAL 5'-PHOSPHATE SYNTHASE SUBUNIT SNZ1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01680">
        <property type="entry name" value="SOR_SNZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029271">
        <property type="entry name" value="Pdx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01235">
        <property type="entry name" value="PDXS_SNZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51129">
        <property type="entry name" value="PDXS_SNZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0704">Schiff base</keyword>
    <feature type="domain" description="PdxS/SNZ N-terminal" evidence="11">
        <location>
            <begin position="12"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with D-ribose 5-phosphate" evidence="8">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="238"/>
            <end position="239"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR029271-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR029271-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG93788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="296" mass="32767" checksum="BD9EBD317FA61E9A" modified="2017-02-15" version="1">MEDHRDSDGILLKHGFCEMLKGGVIMDVKNVEQAKIAEECGAIGVMVLENIPSELRNREEVARSVDPIKIEEIKKAVSINVLAKVRIGHFVESQILEELKIDMIDESEVLTVADENNYINKHKFKTPFVCGCTNLGEALRRISEGASMIRTKGEAGTGNIIEAIKHIRTINNDIKFLCALSENEIYNYAKKINTPIDLLLLTKKLKKLPVVNFAAGGIATPADAAMCMQLGMDGVFVGSGIFESENPRKMASSIVYAVSYFNNPKILLDVSYNLGKAMCGSTKISEKWKNKKKNEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNW2</accession>
    <name>A0A1J1GNW2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein uS10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00379700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526914.1">
        <property type="nucleotide sequence ID" value="XM_028670131.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNW2"/>
    <dbReference type="GeneID" id="39732327"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00379700"/>
    <dbReference type="OMA" id="WCEYRRR"/>
    <dbReference type="OrthoDB" id="10248551at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.600:FF:000004">
        <property type="entry name" value="30S ribosomal protein S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.600">
        <property type="entry name" value="Ribosomal protein S10 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00508">
        <property type="entry name" value="Ribosomal_uS10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001848">
        <property type="entry name" value="Ribosomal_uS10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027486">
        <property type="entry name" value="Ribosomal_uS10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036838">
        <property type="entry name" value="Ribosomal_uS10_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005729">
        <property type="entry name" value="Ribosomal_uS10_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01046">
        <property type="entry name" value="uS10_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11700">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S10 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00338">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00971">
        <property type="entry name" value="RIBOSOMALS10"/>
    </dbReference>
    <dbReference type="SMART" id="SM01403">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54999">
        <property type="entry name" value="Ribosomal protein S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS10" evidence="5">
        <location>
            <begin position="16"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG94093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="114" mass="12998" checksum="82C2CFEC5814F523" modified="2017-02-15" version="1">MKGATDAEKYRLRRIRIALTSKNLRAIEKVCSDIMKGAKEKNLNVSGPVRLPVKTLRITTRKSPCGEGTNTWDRFELRIYKRLIDLYSQCEVVTQMTSINIDPVVEVEVIITDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNX5</accession>
    <name>A0A1J1GNX5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00068700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG92983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525805.1">
        <property type="nucleotide sequence ID" value="XM_028672087.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNX5"/>
    <dbReference type="GeneID" id="39729212"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00068700"/>
    <dbReference type="OrthoDB" id="347622at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012249864" evidence="1">
        <location>
            <begin position="20"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG92983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="510" mass="60778" checksum="530516059346E6B6" modified="2017-02-15" version="1">MLRNKFLFIFLVFLNIVNSKKIKNILSLNFLSTFNENLNNDNFFFSYKKKNKINKKIAKHKFGEHFIRCNKRNVNLNYSYKKKNDKEGKIILRESVREDSQKDNDDIKKVEKNYTPERIEELNKEDLSVNKQENEHSLLNYNNKNELEKEIISEKIENQKNEIIKKSKLPIIGTQLKPSGGFTKELLNIIRESNDYINVINQEIIKDKVNKKLSGNDLSYFDNEETLEEHEFNYLNKIYDNNHVLNMYNFLLVWKKKKNIDLSVFVSKITENSNIMPGERTVIKFSEIEKVQYLKKIKKNRNVCIAMIFVDNKNNNNDESVINHNMFPIGIMAHPLDISLLDKSGEISVLNLFRFKINNYNVTENDFLVNCDLFIDNMQKLNNFELTQENKKIIMNLYDKILDLKIKYNEKIGKTHENEKLKYLEKITDRIDEYVNVLSTNKSIDFRSNKLNFFTSLYLEYFSFLSLDIHANIQTKLQMMYTDNTELRLHNVKTFLMQIYDDLKYKLKVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNX6</accession>
    <name>A0A1J1GNX6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">U3 small nucleolar RNA-associated protein 25</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00381300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UTP25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526930.1">
        <property type="nucleotide sequence ID" value="XM_028670149.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNX6"/>
    <dbReference type="GeneID" id="39732343"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00381300"/>
    <dbReference type="OMA" id="FYERCTF"/>
    <dbReference type="OrthoDB" id="10264378at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034511">
        <property type="term" value="F:U3 snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010678">
        <property type="entry name" value="UTP25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053939">
        <property type="entry name" value="UTP25_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053940">
        <property type="entry name" value="UTP25_NTPase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12933">
        <property type="entry name" value="ORF PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12933:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 25 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06862">
        <property type="entry name" value="Utp25_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22916">
        <property type="entry name" value="UTP25_NTPase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UTP25 NTP hydrolase-like" evidence="7">
        <location>
            <begin position="497"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="domain" description="UTP25 NTP hydrolase-like" evidence="7">
        <location>
            <begin position="719"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="domain" description="UTP25 C-terminal" evidence="6">
        <location>
            <begin position="831"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="122"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="685"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="525"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="128"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="685"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="706"/>
            <end position="718"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF22916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1004" mass="120721" checksum="D57555066E51001A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPN6</accession>
    <name>A0A1J1GPN6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00410900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527223.1">
        <property type="nucleotide sequence ID" value="XM_028670474.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPN6"/>
    <dbReference type="GeneID" id="39732639"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00410900"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="298"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="329" mass="39222" checksum="C7292AAF5973A360" modified="2017-02-15" version="1">MSLLYNKGCEDSGEFIKCLMSLCPINPNKLQSSYCTVEPKFVITQRPFNNALINISKNIFTYEHYGPDYKSSITILSNEDNDGILILYEYNPWYFKYPKETYLCRLRNKNQKISLCESINVNYIGKSISFNSYDIINRDDKKNNQISMKHLKNPKHRIIKLKYNEITLEKYYRHYVRTKYNPHQIYRYIICEKDDHGNTMCANSNYNGKLIHLIEQYGFSPRNEERIVYLPNKCLKSDSNLLCTPYMCIKNDFNESYSCEYEEISIVKNIFPSPETFKVISTNNQAIYHESNLRSSSVYAMTLMPFLIIFIFFFCYMYKIFRKKRRKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPP2</accession>
    <name>A0A1J1GPP2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">E3 ubiquitin-protein ligase RBX1, putative</fullName>
            <ecNumber evidence="13">6.3.2.19</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">RBX1</name>
        <name evidence="13" type="ORF">PGAL8A_00397200</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RING-box family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.19" evidence="13"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527089.1">
        <property type="nucleotide sequence ID" value="XM_028670326.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPP2"/>
    <dbReference type="GeneID" id="39732502"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00397200"/>
    <dbReference type="OMA" id="NACPLDN"/>
    <dbReference type="OrthoDB" id="8962942at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031463">
        <property type="term" value="C:Cul3-RING ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16485">
        <property type="entry name" value="mRING-H2-C3H2C2D_RBX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000273">
        <property type="entry name" value="E3 ubiquitin-protein ligase RBX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051031">
        <property type="entry name" value="RING-box_E3_Ubiquitin_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024766">
        <property type="entry name" value="Znf_RING_H2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11210">
        <property type="entry name" value="RING BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12678">
        <property type="entry name" value="zf-rbx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="12">
        <location>
            <begin position="44"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG94268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="107" mass="12494" checksum="DF4C55F0CB57698F" modified="2017-02-15" version="1">MIENKKNDNKGIFKVNKWSAVAAWSWDISVDNCAICRNHIMDLCIECQAKLNDNENEKEKKIDKENCTVAWGICNHAFHLHCISRWIKARQVCPLDNTNWEFQKATD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPT1</accession>
    <name>A0A1J1GPT1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Novel putative transporter 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">NPT1</name>
        <name evidence="9" type="ORF">PGAL8A_00100900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC43A transporter (TC 2.A.1.44) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526125.1">
        <property type="nucleotide sequence ID" value="XM_028672743.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPT1"/>
    <dbReference type="GeneID" id="39729533"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00100900"/>
    <dbReference type="OMA" id="QAPRRMF"/>
    <dbReference type="OrthoDB" id="330047at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052599">
        <property type="entry name" value="SLC43A_AATransporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20772">
        <property type="entry name" value="PROTEIN FMP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20772:SF2">
        <property type="entry name" value="PROTEIN FMP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="177"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="206"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="331"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="371"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="397"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="425"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="459"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="494"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="529" mass="59952" checksum="8446A708893DD620" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPT8</accession>
    <name>A0A1J1GPT8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Beta-ketoacyl-ACP synthase III, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00402000</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the thiolase-like superfamily. FabH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527137.1">
        <property type="nucleotide sequence ID" value="XM_028670379.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPT8"/>
    <dbReference type="GeneID" id="39732550"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00402000"/>
    <dbReference type="OMA" id="WGSEGDK"/>
    <dbReference type="OrthoDB" id="428487at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00830">
        <property type="entry name" value="KAS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013747">
        <property type="entry name" value="ACP_syn_III_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013751">
        <property type="entry name" value="ACP_syn_III_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004655">
        <property type="entry name" value="FabH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00747">
        <property type="entry name" value="fabH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006829">
        <property type="entry name" value="PRK09352.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34069">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34069:SF2">
        <property type="entry name" value="BETA-KETOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08545">
        <property type="entry name" value="ACP_syn_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08541">
        <property type="entry name" value="ACP_syn_III_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012430208" evidence="10">
        <location>
            <begin position="18"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-ketoacyl-[acyl-carrier-protein] synthase III N-terminal" evidence="12">
        <location>
            <begin position="151"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal" evidence="11">
        <location>
            <begin position="283"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG94316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="369" mass="41825" checksum="45E05B612530A0A6" modified="2017-02-15" version="1">MLLYIISFLFIHNGVFLLETNKNNKYNFINSVKNIPYTYKIRAAVKFGGKIIGHGHSYPSNEIKNDELKKYVETSDDWIRTRTGIKKRRILKRNENLSMLQIESANQALKSCSLNPLDIDMIINASSTPQNLFGDANNISNKIGCKNSVNMDLTAACTGFVFAFVTAYNFLPRYKNILVIGSDALSNFVDWRDRNTCVLFGDASGAVVLQRTEDNEENKIYNYYIGSNSELNDLLTINFENNSYNLDNPNVNKYGKLNMDGKEVFKYTINNLPNILQKAIYDSNINIEDIDYFVFHQANIRIIQTVAKKLDIPMSKVLVNLEEHANTSAASIPLCFSENIQNGKIKKNDIICMCGFGAGMSYGCIIFKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPU9</accession>
    <name>A0A1J1GPU9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 10">tRNA(His) guanylyltransferase</fullName>
            <ecNumber evidence="2 10">2.7.7.79</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">tRNA-histidine guanylyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PGAL8A_00183700</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a 5'-end ribonucleotide-tRNA(His) + GTP + ATP + H2O = a 5'-end phospho-guanosine-ribonucleotide-tRNA(His) + AMP + 2 diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54564"/>
            <dbReference type="Rhea" id="RHEA-COMP:14193"/>
            <dbReference type="Rhea" id="RHEA-COMP:14917"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:138282"/>
            <dbReference type="ChEBI" id="CHEBI:141847"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.7.79"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="12">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the tRNA(His) guanylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.79" evidence="2 10"/>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527266.1">
        <property type="nucleotide sequence ID" value="XM_028670522.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPU9"/>
    <dbReference type="GeneID" id="39730364"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00183700"/>
    <dbReference type="OMA" id="WKQHTEI"/>
    <dbReference type="OrthoDB" id="62560at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008193">
        <property type="term" value="F:tRNA guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025845">
        <property type="entry name" value="Thg1_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024956">
        <property type="entry name" value="tRNAHis_GuaTrfase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007537">
        <property type="entry name" value="tRNAHis_GuaTrfase_Thg1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038469">
        <property type="entry name" value="tRNAHis_GuaTrfase_Thg1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12729">
        <property type="entry name" value="TRNA(HIS) GUANYLYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12729:SF6">
        <property type="entry name" value="TRNA(HIS) GUANYLYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04446">
        <property type="entry name" value="Thg1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14413">
        <property type="entry name" value="Thg1C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028980">
        <property type="entry name" value="tRNAHis_guanylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 11" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8 10 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 10 15" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNAHis guanylyltransferase catalytic" evidence="13">
        <location>
            <begin position="7"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Thg1 C-terminal" evidence="14">
        <location>
            <begin position="137"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="75"/>
            <end position="76"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR028980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR028980-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR028980-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF14413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG94445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="317" mass="38471" checksum="FE65277C0AF14F69" modified="2017-02-15" version="1">MANSKFSYVKLYEEEKKILFNCFFVLRIDGCDFKNFIKDHEYNKPNDIKGLNLMNECAIEVLKKFSEIDLCYGHSDEYSFLFRKTTKLWNRRYNKILSNVVSYFTSSFVHKWKNFFKKDLVYLPCFDARIITYPSEKEIKDYFSWRQVDCHINTQYNECFWNLILKDNYTNEEAHKFLLTTQTKDKNELLFTRFNINYNNIPEIFRRGTIIIRNKNFQKKITPNIKFNKEFDNTTKLDQHQSIKDNCNINTSVHFKDNFNLYSNENIVDNSDMKFNQELNDNLSKFIISHENLISEKFWNKYSYIFKTKEKKEEQQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPV8</accession>
    <name>A0A1J1GPV8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00193900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000029">
        <property type="protein sequence ID" value="CRG94541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527356.1">
        <property type="nucleotide sequence ID" value="XM_028670622.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPV8"/>
    <dbReference type="GeneID" id="39730464"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00193900"/>
    <dbReference type="OMA" id="LMCDYLK"/>
    <dbReference type="OrthoDB" id="332663at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="322"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="572"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="572"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="588"/>
            <end position="607"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1185" mass="141676" checksum="90C02D252AB416DB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPX1</accession>
    <name>A0A1J1GPX1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00405200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527169.1">
        <property type="nucleotide sequence ID" value="XM_028670414.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPX1"/>
    <dbReference type="GeneID" id="39732582"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00405200"/>
    <dbReference type="OMA" id="HAYCNSL"/>
    <dbReference type="OrthoDB" id="382379at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="294" mass="34890" checksum="14162E034AE5F28A" modified="2017-02-15" version="1">MMNSSKRFYINLILLNKKVKFSYNREISSNSIFYHKNDLIKVNEEINNLEEAFIRRISKMNNTALAYACEDINKNKINNLHIWKLIYNRTKEISNSFSLSELVVMFHAYCRSISFDQNFINLINLFWSLIENKLNDLDYLSLIALYFCAEKTKNSQKMEEISNLLLKNILHERDNIKLKEKGLMIILKILCDDKKKIDEEHIKNICNIVQKVDIKEIKNILLCMQFFLKYKAFDEPFIILLKKIQSLLIFKKINPYDILKHLYYISNINNPIILEEVKNTLSIIYLSHSISKGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ72</accession>
    <name>A0A1J1GQ72_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GTP:AMP phosphotransferase, putative</fullName>
            <ecNumber evidence="5">2.7.4.10</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">GAK</name>
        <name evidence="5" type="ORF">PGAL8A_00089000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the adenylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.10" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526008.1">
        <property type="nucleotide sequence ID" value="XM_028671444.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ72"/>
    <dbReference type="GeneID" id="39729414"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00089000"/>
    <dbReference type="OMA" id="SCTMLIC"/>
    <dbReference type="OrthoDB" id="439792at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:AMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046899">
        <property type="term" value="F:nucleoside triphosphate adenylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006259">
        <property type="entry name" value="Adenyl_kin_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01351">
        <property type="entry name" value="adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4 5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="222" mass="25654" checksum="2B4A05A7D4025BDA" modified="2017-02-15" version="1">MKIVFFGAPGVGKGTFAEILSKKEKIKHINIGNILRNEIKKESNLGKEIKKIVKSGNLVEDNLIVNIVDEEIKNSLNKYKGFILDGFPRNILQSKELIKITTIDLFINIYLPKHILIKKLLGRRLCNICDNNFNVANIQENEFDMPPILPSKECNTCNGNANLTKRSDDNEEVIKHRLNSYESIYLPIINFFKNSNYTIIDFELKKGIKDFDRLYNIILKYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ88</accession>
    <name>A0A1J1GQ88_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-f protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00186400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000025">
        <property type="protein sequence ID" value="CRG94469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527289.1">
        <property type="nucleotide sequence ID" value="XM_028670548.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ88"/>
    <dbReference type="GeneID" id="39730391"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00186400"/>
    <dbReference type="OrthoDB" id="384111at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="591" mass="71021" checksum="A3A46CBB36E1FED2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQN3</accession>
    <name>A0A1J1GQN3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Vacuole membrane protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00196700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527387.1">
        <property type="nucleotide sequence ID" value="XM_028670657.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQN3"/>
    <dbReference type="GeneID" id="39730494"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00196700"/>
    <dbReference type="OMA" id="EEPYDKR"/>
    <dbReference type="OrthoDB" id="2016540at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="343"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="383" mass="45375" checksum="9F66F59E527874ED" modified="2017-02-15" version="1">MDTYDAKKKELYLKRKNINLYYHPIKTFNLFCLELKNIFLKLYTKNKKYNKIILALLSVILLLFKLRTRYEHLNNFIIYIEVFIWWLSLGILSSIGLGCGMHSGVLFLFPHIYFICSTSEYCNSLNFDSRLNMWRSILTSGNYFECLGRDDGNITLSRLFFKIYPYCFIWGLGTALGELPPYLTSYYASKTKLSDDDYEEFEKDIKEGKKNIITSMKIWMINFIKKYGAISVFLLSCWPNVMFDLCGICCGHFLMPFEKFFIPLVLGKAVVKTIFQCFFLIFLFSNNYKDLQLKILQKCFSFLPIHIFSKNLRDVSFLEKYIDEKISILKYGKKSKSKTNFMFLFNIFFFLVIIIFFISCINQIAQKHQKNIDDEQLKSLKRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQN8</accession>
    <name>A0A1J1GQN8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA-intron lyase</fullName>
            <ecNumber evidence="2">4.6.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00213300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>pretRNA = a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus.</text>
            <dbReference type="EC" id="4.6.1.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the tRNA-intron endonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.16" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527551.1">
        <property type="nucleotide sequence ID" value="XM_028670838.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQN8"/>
    <dbReference type="GeneID" id="39730660"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00213300"/>
    <dbReference type="OMA" id="KGIIAYV"/>
    <dbReference type="OrthoDB" id="48041at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000213">
        <property type="term" value="F:tRNA-intron lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006388">
        <property type="term" value="P:tRNA splicing, via endonucleolytic cleavage and ligation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22363">
        <property type="entry name" value="tRNA-intron_lyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036167">
        <property type="entry name" value="tRNA_intron_Endo_cat-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006677">
        <property type="entry name" value="tRNA_intron_Endonuc_cat-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01974">
        <property type="entry name" value="tRNA_int_endo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53032">
        <property type="entry name" value="tRNA-intron endonuclease catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA intron endonuclease catalytic" evidence="4">
        <location>
            <begin position="7"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00034031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="94" mass="11146" checksum="0C2D6AA9E4542102" modified="2017-02-15" version="1">MILKNVKREVVFNDLNKYFIVVDGFKYGADYILYKNSIGHEHGFALVFIKDNVILNDKEKIIIVRICESVKKKAIIAYVNEETLEIRYEEIYRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQQ0</accession>
    <name>A0A1J1GQQ0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">tRNA binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00201500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527433.1">
        <property type="nucleotide sequence ID" value="XM_028670707.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQQ0"/>
    <dbReference type="GeneID" id="39730541"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00201500"/>
    <dbReference type="OMA" id="DIFYFCS"/>
    <dbReference type="OrthoDB" id="19141at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02799">
        <property type="entry name" value="tRNA_bind_EMAP-II_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000287">
        <property type="entry name" value="Methionine-tRNA ligase, beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053836">
        <property type="entry name" value="Arc1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051270">
        <property type="entry name" value="Tyrosine-tRNA_ligase_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11586:SF33">
        <property type="entry name" value="AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11586">
        <property type="entry name" value="TRNA-AMINOACYLATION COFACTOR ARC1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21972">
        <property type="entry name" value="Arc1p_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 3" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="TRNA-binding" evidence="5">
        <location>
            <begin position="235"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="208"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG94618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="397" mass="46141" checksum="0030D9887F550C76" modified="2017-02-15" version="1">MYTLTLVKDDIRSEILKLVLDYIKVMIVNDEKVTFPELIYNEKISFDNKNKKYKGFFCSLYSLIDFYNCFSELFNEDEGKISENEELIFHVASDKYILKQSDLKHLNDLLVEKSYIVSDKHSSIVDIFYFCSIHKLLDEMPFKERVEYSHIFRWFLHIQETLIGSFSTLKKLDVRDSLETFMTNKNLRNTNEKINSTKVGENKKENLKNENAKNKKKNVQNKNVKNTEEPRSLDDISRLNIIVGYVEHVEIHPDADTLYCLKVNVGEEKVRDICSGLRNKKKAEDLINQYVLVLANLKEKSLRGRKSHGMILCGSFEDRIELLHPPSGAKIGERIISENMDIKSLPDKTLSFDKEKNPFYHIQPHLILKNGIAHYKDTKLISSQGDVKCVLQEGTIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQQ8</accession>
    <name>A0A1J1GQQ8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00202300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527441.1">
        <property type="nucleotide sequence ID" value="XM_028670716.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQQ8"/>
    <dbReference type="GeneID" id="39730549"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00202300"/>
    <dbReference type="OMA" id="LHIKDPE"/>
    <dbReference type="OrthoDB" id="378673at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="307"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="353"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="222"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="241"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="534" mass="62857" checksum="14FF5A21B71CAE0A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQU4</accession>
    <name>A0A1J1GQU4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Para-hydroxybenzoate--polyprenyltransferase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00136000</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UbiA prenyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526477.1">
        <property type="nucleotide sequence ID" value="XM_028674892.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQU4"/>
    <dbReference type="GeneID" id="39729885"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00136000"/>
    <dbReference type="OMA" id="WCMIYDT"/>
    <dbReference type="OrthoDB" id="18170at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13959">
        <property type="entry name" value="PT_UbiA_COQ2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1780:FF:000001">
        <property type="entry name" value="4-hydroxybenzoate octaprenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1780">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039653">
        <property type="entry name" value="Prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030470">
        <property type="entry name" value="UbiA_prenylTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11048:SF28">
        <property type="entry name" value="4-HYDROXYBENZOATE POLYPRENYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11048">
        <property type="entry name" value="PRENYLTRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00943">
        <property type="entry name" value="UBIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="232"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="283"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="309"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="382"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="418"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="457" mass="54403" checksum="9E1851B6FED5595C" modified="2017-02-15" version="1">MKKQYQSNFKIYIKYNKFHYLQNKIKCEHFSSSNKKLYMYNEKKYFIRCENRNYNVNFVHKNNVNLPKIYDFIRSQKKYRKNVPVFTNNNYNLNNLENVKDNLKMIQKYNYCVNMNSKRKKKGDCANNIKEIIKSNIKSYIILSRLHIPDGVYLLFYSALYGYFLTYNVDNLLINNELNIKEINEIFKNIGLFLFGSINSRIVGCIINDFFDKNFDRYVERTKNRPLANNTISTKKALAYFCIHGSLALLTLFQFNYQTICIGLFSTFFITTYPLLKRITYYAQIYLSFTFNLGFLIASSVNLDVISNIIPLFISFLPLSLLTIIYDTIYAHQDKKDDLKLNLKSLAIKWDQKTLKNSKFLAFNMLYLFYLTGYLFNIHYTYYILSTFNILYLYYNLNQSSLNDKEKCMKFFKKSKHILLLIAFSALFAKSCELWEKGKNKKINNKETQNEVKKTDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQW4</accession>
    <name>A0A1J1GQW4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00207900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527497.1">
        <property type="nucleotide sequence ID" value="XM_028670779.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQW4"/>
    <dbReference type="GeneID" id="39730606"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00207900"/>
    <dbReference type="OMA" id="DTQLWEI"/>
    <dbReference type="OrthoDB" id="416217at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="1">
        <location>
            <begin position="105"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="300" mass="35442" checksum="A0D280B6545167ED" modified="2017-02-15" version="1">MSSLINYSKFEKLEVSSSDEESRNRKPQITTLNNNDKVMIGPNGLTILKNADEKKTNEINKNIQCLEGEEVDDKNKEILKKENINNKDIMKNETIFKNMVINGGVIPFKCIWNQSIHYINGYISLPLHSKAKYLVVEIYEDKLIVKKKKLSNTLNDESKKKNDLNNYDILIDKYFYFKINMNEDTQLWEIKNMKINWHEIFYLSNKINNQTVEFNFGENTVEKEETFLYISLKKKSEIENSYIWWRSLFKDGEKINISNLPARISINKNNNNISFKNVWDEAHKIFKKKISEKNPYPIDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR04</accession>
    <name>A0A1J1GR04_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">40S ribosomal protein S3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00225300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527671.1">
        <property type="nucleotide sequence ID" value="XM_028670971.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR04"/>
    <dbReference type="GeneID" id="39730780"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00225300"/>
    <dbReference type="OMA" id="NKKKWMI"/>
    <dbReference type="OrthoDB" id="10248446at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02413">
        <property type="entry name" value="KH-II_40S_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1140.32:FF:000005">
        <property type="entry name" value="40S ribosomal protein S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.20:FF:000006">
        <property type="entry name" value="40S ribosomal protein S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.32">
        <property type="entry name" value="Ribosomal protein S3, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036419">
        <property type="entry name" value="Ribosomal_S3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057258">
        <property type="entry name" value="Ribosomal_uS3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001351">
        <property type="entry name" value="Ribosomal_uS3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005703">
        <property type="entry name" value="Ribosomal_uS3_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003219">
        <property type="entry name" value="PRK04191.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01008">
        <property type="entry name" value="uS3_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11760">
        <property type="entry name" value="30S/40S RIBOSOMAL PROTEIN S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11760:SF32">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00189">
        <property type="entry name" value="Ribosomal_S3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="Prokaryotic type KH domain (KH-domain type II)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54821">
        <property type="entry name" value="Ribosomal protein S3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="KH type-2" evidence="7">
        <location>
            <begin position="21"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="222" mass="24680" checksum="ABCB95F148F98A54" modified="2017-02-15" version="1">MSAPISKKRKFINDGVFQAELNEFLARILAEDGYSGVEVRVTPIRTEVIIRATRTREVLGDKGRRIRELTSLVQKRFFNKSTNSVELFAERVEHRGLCAMAQAESLRYKLLKGLAVRRACYGVLRHIMESGAKGCEVIVSGKLRAQRAKSMKFRDGYLISTGEPSKRFVNTATRSAQLKQGVLGIKVKIMLPTAIDTKTGLPSILPDSISVLEPKTDTVDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR35</accession>
    <name>A0A1J1GR35_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">LCCL domain-containing protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CCp2</name>
        <name evidence="4" type="ORF">PGAL8A_00215100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527569.1">
        <property type="nucleotide sequence ID" value="XM_028670858.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730678"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00215100"/>
    <dbReference type="OMA" id="CQMCCQS"/>
    <dbReference type="OrthoDB" id="414826at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.560">
        <property type="entry name" value="Exo-inulinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.20">
        <property type="entry name" value="LCCL-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051957">
        <property type="entry name" value="CRISP-LCCL_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000421">
        <property type="entry name" value="FA58C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036056">
        <property type="entry name" value="Fibrinogen-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004043">
        <property type="entry name" value="LCCL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036609">
        <property type="entry name" value="LCCL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31331:SF1">
        <property type="entry name" value="CYSTEINE RICH SECRETORY PROTEIN LCCL DOMAIN CONTAINING 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31331">
        <property type="entry name" value="LCCL DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G08630)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00754">
        <property type="entry name" value="F5_F8_type_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03815">
        <property type="entry name" value="LCCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00603">
        <property type="entry name" value="LCCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56496">
        <property type="entry name" value="Fibrinogen C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69848">
        <property type="entry name" value="LCCL domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50022">
        <property type="entry name" value="FA58C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009618922" evidence="2">
        <location>
            <begin position="23"/>
            <end position="1581"/>
        </location>
    </feature>
    <feature type="domain" description="F5/8 type C" evidence="3">
        <location>
            <begin position="280"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="461"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1581" mass="179373" checksum="2FD8A93044A780FA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR59</accession>
    <name>A0A1J1GR59_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00242100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527836.1">
        <property type="nucleotide sequence ID" value="XM_028671156.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR59"/>
    <dbReference type="GeneID" id="39730949"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00242100"/>
    <dbReference type="OMA" id="EDNMDSY"/>
    <dbReference type="OrthoDB" id="377650at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="917"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="948"/>
            <end position="974"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1019" mass="121692" checksum="9766555FC601C6D4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRB0</accession>
    <name>A0A1J1GRB0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Thrombospondin-related anonymous protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">TRAP</name>
        <name evidence="11" type="ORF">PGAL8A_00247000</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527884.1">
        <property type="nucleotide sequence ID" value="XM_028671209.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRB0"/>
    <dbReference type="SMR" id="A0A1J1GRB0"/>
    <dbReference type="GeneID" id="39730998"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00247000"/>
    <dbReference type="OMA" id="PEDNDWN"/>
    <dbReference type="OrthoDB" id="372508at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd01471">
        <property type="entry name" value="vWA_micronemal_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.100.10">
        <property type="entry name" value="Thrombospondin type-1 (TSP1) repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000884">
        <property type="entry name" value="TSP1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036383">
        <property type="entry name" value="TSP1_rpt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16059">
        <property type="entry name" value="ANTHRAX TOXIN RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16059:SF25">
        <property type="entry name" value="LYSOZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00090">
        <property type="entry name" value="TSP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00209">
        <property type="entry name" value="TSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82895">
        <property type="entry name" value="TSP-1 type 1 repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50092">
        <property type="entry name" value="TSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012656048" evidence="9">
        <location>
            <begin position="25"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="10">
        <location>
            <begin position="44"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="287"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="575"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="296"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="306"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="453"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="495"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="535"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="591"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="603"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG95071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="614" mass="69714" checksum="54D4CCFC46D9D361" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRC6</accession>
    <name>A0A1J1GRC6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00248700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527900.1">
        <property type="nucleotide sequence ID" value="XM_028671227.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRC6"/>
    <dbReference type="GeneID" id="39731015"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00248700"/>
    <dbReference type="OMA" id="FNTNERY"/>
    <dbReference type="OrthoDB" id="363951at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="18"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="166"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="279"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="603" mass="72133" checksum="D9E84C3557430354" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRD3</accession>
    <name>A0A1J1GRD3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00241900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527834.1">
        <property type="nucleotide sequence ID" value="XM_028671153.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRD3"/>
    <dbReference type="GeneID" id="39730947"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00241900"/>
    <dbReference type="OMA" id="NDYLFHA"/>
    <dbReference type="OrthoDB" id="372779at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="355" mass="41455" checksum="E6507FB8EE0E5A5E" modified="2017-02-15" version="1">MGFLVKNEKVINENSEGINNENKINEKYLDSNGKKNFLYTFYDINKKENDNNIYTCKNLSSSNILTNQINNINSRNNNYSSEGYIDNLNNMNNEELLTNKINFNDNKNNSCINENNLYNGNDNSFINNNNLNKSNNFFLNVKNDSLMNDVLNNSNCSYLNERNSNKINNEDVLNDNNLKEVCQNSFINEKKLDKINKENSIDKIKNIQRLYNNSHKVSNGYFNSNKNNLIKLNSSYINEQNLINEDIDLNKNCVKQFNNSATKKDIIKSDFDQSNEYNFLEINNEEQNEVIKKKIKKKINENDYLFHAINELLEVGLKNECIPLFERLQQNLFFLVMLANIPNEKFDDIEGSSDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRD7</accession>
    <name>A0A1J1GRD7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="13">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">PPKL</name>
        <name evidence="16" type="ORF">PGAL8A_00225500</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PPP phosphatase family. BSU subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="13"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527673.1">
        <property type="nucleotide sequence ID" value="XM_028670973.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRD7"/>
    <dbReference type="GeneID" id="39730782"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00225500"/>
    <dbReference type="OMA" id="FRHTSWM"/>
    <dbReference type="OrthoDB" id="309851at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009742">
        <property type="term" value="P:brassinosteroid mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07419">
        <property type="entry name" value="MPP_Bsu1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.120.10.80:FF:000077">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000008">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041758">
        <property type="entry name" value="MPP_BSL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012391">
        <property type="entry name" value="Ser/Thr_prot_Pase_BSU1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46422">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE BSL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46422:SF4">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE BSL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036363">
        <property type="entry name" value="PPP_BSU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="9" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="15">
        <location>
            <begin position="638"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="852"/>
            <end position="873"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="CRG94858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="873" mass="99215" checksum="261CCCDF7D578733" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRJ6</accession>
    <name>A0A1J1GRJ6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00248400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527898.1">
        <property type="nucleotide sequence ID" value="XM_028671225.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731012"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00248400"/>
    <dbReference type="OMA" id="TMKNFHN"/>
    <dbReference type="OrthoDB" id="378857at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35310">
        <property type="entry name" value="CELL WALL INTEGRITY/STRESS RESPONSE COMPONENT-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35310:SF1">
        <property type="entry name" value="CELL WALL INTEGRITY_STRESS RESPONSE COMPONENT-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="985"/>
            <end position="1319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2061"/>
            <end position="2082"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="985"/>
            <end position="1227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1228"/>
            <end position="1240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1241"/>
            <end position="1265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1282"/>
            <end position="1295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1298"/>
            <end position="1319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2067"/>
            <end position="2082"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2082" mass="244873" checksum="408402D5A8ED29A6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRP1</accession>
    <name>A0A1J1GRP1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00233900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527755.1">
        <property type="nucleotide sequence ID" value="XM_028671064.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRP1"/>
    <dbReference type="GeneID" id="39730866"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00233900"/>
    <dbReference type="OMA" id="DCGKSNC"/>
    <dbReference type="OrthoDB" id="126772at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013221412" evidence="1">
        <location>
            <begin position="24"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="284" mass="32269" checksum="21B28C8AAA7DD5E3" modified="2017-02-15" version="1">MTLKKFTLLSFVLIVAFLHKQLKNDFFLFKFFKVNSVIVGKTANDYALNEAISTILKHAPEENETEIYDNINKVMSEAYNNFNTRKILIRISYLIENGKLDYLCDKNYLKIILGIPQIISSAELLEDLKLYKLKKLIENIVNSLVICKPKDFKRKFYLESGGCQSDSDKAIIFDNGKLKKRNSLQLKPKNKFFSILLKCSVDNLGSGDKTMVCVKEELSKENLKISESCSNCFKDSVDCGKSNCWLSCLFSDPCGDNCFHCGVNYCKKDLISCTGLKNLPDACI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS02</accession>
    <name>A0A1J1GS02_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CPW-WPC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00152800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526640.1">
        <property type="nucleotide sequence ID" value="XM_028675072.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS02"/>
    <dbReference type="GeneID" id="39730052"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00152800"/>
    <dbReference type="OMA" id="KHKPHVC"/>
    <dbReference type="OrthoDB" id="380440at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006387">
        <property type="entry name" value="CPW_WPC_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01492">
        <property type="entry name" value="CPW_WPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09717">
        <property type="entry name" value="CPW_WPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01099">
        <property type="entry name" value="CPW_WPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013244167" description="CPW-WPC domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="CPW-WPC" evidence="2">
        <location>
            <begin position="93"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="179" mass="21049" checksum="6092DE7199AC2C47" modified="2017-02-15" version="1">MNKIYLFIFVLFHLSECMLPWTKKRKAVNQMAIIKDMSKELKNISESLPTQTDITSKIHKIDSEVLEKLDEEIINEENLAKHKPHVCQDSPYERDYSYLCPEGWIKNSIGQCWGIDYDGHCESLKYFQEYSNDEKREFELNCCVLWPKLKNVTKKINRRDNLKGSINSSNGLIIKPKNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS34</accession>
    <name>A0A1J1GS34_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mitochondrial pyruvate carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">MPC1</name>
        <name evidence="10" type="ORF">PGAL8A_00251800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Mediates the uptake of pyruvate into mitochondria.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion inner membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527929.1">
        <property type="nucleotide sequence ID" value="XM_028671259.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS34"/>
    <dbReference type="GeneID" id="39731046"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00251800"/>
    <dbReference type="OMA" id="CTTHFWG"/>
    <dbReference type="OrthoDB" id="1697690at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006850">
        <property type="term" value="P:pyruvate import into mitochondria"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005336">
        <property type="entry name" value="MPC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14154">
        <property type="entry name" value="UPF0041 BRAIN PROTEIN 44-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03650">
        <property type="entry name" value="MPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="48"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG95116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="106" mass="12269" checksum="531A09F443149F45" modified="2017-02-15" version="1">MSKFKLFYDKVKSNAFSILFWAPLANWGFVLAGCNDLMKSPVYVSEKMTAVLSVYSILFMRFSLAIRPKNYLLFACHATNTLVQSVLLYRKLKFEADNKKNLKEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSL1</accession>
    <name>A0A1J1GSL1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00267700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000037">
        <property type="protein sequence ID" value="CRG95474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528284.1">
        <property type="nucleotide sequence ID" value="XM_028671653.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSL1"/>
    <dbReference type="GeneID" id="39731206"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00267700"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006496">
        <property type="entry name" value="CHP01606_Plasmodium_spp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09688">
        <property type="entry name" value="Wx5_PLAF3D7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012904649" evidence="2">
        <location>
            <begin position="23"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="321" mass="38069" checksum="5696A2EA46CDFAE9" modified="2017-02-15" version="1">MNTLSLYLRNTIFLLLIWMYQCFYNFDSNKTLVDKNILQTKNKLKYERVLAEGDISGKKQTYAKECIEESPLGNKKNKCKNPVRYENPYDHWNKVVTPKLREQFDKETSEMDPNWRDQKWNNEWNKISADKVNDLSSIYHRQDISEEEKKELIFPVVHKLFSEFQQFIDECKKEMIGNKTESESKKEMIDNKTESESNNEMTDNKTESESKDEVTDNKTESESKKETIGNKTESESKKEMIDNKTASESKKEMIDNKTESESKNEIIDNKTASESKKEMTDNETASESKNEKRKKKINFKKFDLMKHLIFHKIEKIYDDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSZ0</accession>
    <name>A0A1J1GSZ0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nuclear formin-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">MISFIT</name>
        <name evidence="4" type="ORF">PGAL8A_00275600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528367.1">
        <property type="nucleotide sequence ID" value="XM_028671745.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731288"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00275600"/>
    <dbReference type="OMA" id="CNWLNEP"/>
    <dbReference type="OrthoDB" id="377512at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101447">
        <property type="entry name" value="Formin homology 2 domain (FH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1334"/>
            <end position="1356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="618"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="528"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="627"/>
            <end position="667"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1525" mass="179983" checksum="C9300F3D45AADEDB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT20</accession>
    <name>A0A1J1GT20_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Radical SAM protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00278800</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528399.1">
        <property type="nucleotide sequence ID" value="XM_028671781.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT20"/>
    <dbReference type="GeneID" id="39731321"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00278800"/>
    <dbReference type="OMA" id="GTIKWAM"/>
    <dbReference type="OrthoDB" id="538249at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040072">
        <property type="entry name" value="Methyltransferase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004383">
        <property type="entry name" value="rRNA_lsu_MTrfase_RlmN/Cfr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30544">
        <property type="entry name" value="23S RRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30544:SF5">
        <property type="entry name" value="RADICAL SAM CORE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006004">
        <property type="entry name" value="CHP00048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00275">
        <property type="entry name" value="adenosine_C2_methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01062">
        <property type="entry name" value="methyltransferase_(Class_A)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="11">
        <location>
            <begin position="95"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG95591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="361" mass="42380" checksum="2A6662F0F8287F44" modified="2017-02-15" version="1">MEKSKRYINLVKIIEKNKFEKYRLKQILDNIYKAKIVNINKMKNIPTSLRRELKNIFNENILSLKPLKEYKYDRAYKVLFECKDKEKIETTSLDFGSHKSLCISSQIGCSFACKFCATGQIGIKRQLELDEITDQLLYFQSKNVNIKNVSFMGMGEPLANPHVFDSIHFFNHSDFFSLSNRRINISTVGLLPGIKKLNEFFPQVNLSFSLHSPFSEERDRLVPINRMFPFHEVLDLLDDRIAKTGRRVWISYILIKDINDSKDHAEALCEHICKRPNNIRYLYNVCLIPYNKAKNVDENFQRLNEENRILQFEKILRKHGISFFYRNSFGHSIDAACGQLYADYEPKINKEKIGTRNIPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT51</accession>
    <name>A0A1J1GT51_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rhoptry-associated protein 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RAP1</name>
        <name evidence="3" type="ORF">PGAL8A_00282000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528431.1">
        <property type="nucleotide sequence ID" value="XM_028671816.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT51"/>
    <dbReference type="GeneID" id="39731353"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00282000"/>
    <dbReference type="OrthoDB" id="384877at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050938">
        <property type="entry name" value="Collagen_Structural_Proteins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009864">
        <property type="entry name" value="RAP1_Plasmodium"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37456:SF6">
        <property type="entry name" value="COLLAGEN ALPHA-1(XXIII) CHAIN-LIKE ISOFORM X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37456">
        <property type="entry name" value="SI:CH211-266K2.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07218">
        <property type="entry name" value="RAP1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013176087" evidence="2">
        <location>
            <begin position="23"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="508"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="663"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="110"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="302"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="430"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="670"/>
            <end position="717"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1187" mass="133168" checksum="F79B4D6B6264469E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT69</accession>
    <name>A0A1J1GT69_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S25</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00293100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528534.1">
        <property type="nucleotide sequence ID" value="XM_028671930.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT69"/>
    <dbReference type="GeneID" id="39731464"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00293100"/>
    <dbReference type="OMA" id="CASAYEM"/>
    <dbReference type="OrthoDB" id="10263513at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.63.20:FF:000002">
        <property type="entry name" value="40S ribosomal protein S25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.63.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004977">
        <property type="entry name" value="Ribosomal_eS25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12850">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03297">
        <property type="entry name" value="Ribosomal_S25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="105" mass="11809" checksum="34C33105782A87EA" modified="2017-02-15" version="1">MPPKERKTKEQIAAAAAASGRTKKKKWGKGKNKEKLNHAVFIDKTLHSKILECKNMKVITPSTISEKYKVNLSVARAVIKYLAEKNLINEVCTQSHSQKLYTKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTX9</accession>
    <name>A0A1J1GTX9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00315100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528746.1">
        <property type="nucleotide sequence ID" value="XM_028672166.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTX9"/>
    <dbReference type="GeneID" id="39731684"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00315100"/>
    <dbReference type="OMA" id="DYNENEC"/>
    <dbReference type="OrthoDB" id="372457at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="19"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="668" mass="80595" checksum="4FF00BAAE1DCF2B1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTY9</accession>
    <name>A0A1J1GTY9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein HGH1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00297300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528569.1">
        <property type="nucleotide sequence ID" value="XM_028671969.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTY9"/>
    <dbReference type="GeneID" id="39731506"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00297300"/>
    <dbReference type="OMA" id="YIMLVAN"/>
    <dbReference type="OrthoDB" id="382655at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039717">
        <property type="entry name" value="Hgh1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007205">
        <property type="entry name" value="Protein_HGH1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13387">
        <property type="entry name" value="PROTEIN HGH1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13387:SF9">
        <property type="entry name" value="PROTEIN HGH1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04063">
        <property type="entry name" value="DUF383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein HGH1 N-terminal" evidence="1">
        <location>
            <begin position="114"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="362" mass="42826" checksum="F979FCCE5DBE8212" modified="2017-02-15" version="1">MDMKKEEDATGESNEANENIYEELFSYANSDNEIVKKESLRIILSLLEENELIEYIRKNNKKCFKIIISNLNSRNKMLSLECLLNLSARLPKELTERNIIEILFDMVKEEEKYEENCIDLYIMIISNITRCKEGIYKILDLKEDTNIDINEEKFFVSYYLNKLLYFFFLPIKPSINKNINDKYIYVSHILINISSIKESSLFFKNVSFLNKISEQILNKDRFRAILPFIINLCLNETTHNYLFHDSCILFPYILSYIYTNNYSLCSNNIYNSNNVEKSDNIHHIILQKATVLINCSIIKSRIIIILLYLCKKDYSREKLHNYGIYDILRNWKSHEKDTELLSDIENIADKFEAKKNGKAFIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTZ4</accession>
    <name>A0A1J1GTZ4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fam-i protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00321100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000047">
        <property type="protein sequence ID" value="CRG95998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528806.1">
        <property type="nucleotide sequence ID" value="XM_028672234.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTZ4"/>
    <dbReference type="GeneID" id="39731744"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00321100"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="118"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="297"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="388" mass="47701" checksum="6098A730BADF9AF2" modified="2017-02-15" version="1">MDLKLSDATSIDSNDNLNGGNSTVEFAHREIEGATVSIPENPLYDDLDLRDAIQNPSEDINLDSTSSTNLHHKNLLSIFHLVMIIISFLRFARTYSPKLRAKHKERVRLQNKWDNRDKKMKGDWKKMEEKWNERKQKENREKEELNKKKEEREKKTNNEMEQFNRKWDGENYSEEKSWKFLNYSCINGKCIKSLNEPSTSQTCNKIVKRKKKNKVLLDIIEEKLKGISFKKPISEHELIKKITEEEKKRRETLFRQVVELNEKWKKYEEYCQIRREWERNERKKLEEKRRKRKGKHENEMLKEKVEWEKSMREEKEKWEKIMKEENEKWEKNMRKEKEKWQNRMMEKNEEWKKDENKKIKKEESELNSKWRYEHYKIKEKEGKKIRKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU48</accession>
    <name>A0A1J1GU48_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fam-h protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00322300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000049">
        <property type="protein sequence ID" value="CRG96010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528818.1">
        <property type="nucleotide sequence ID" value="XM_028672247.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU48"/>
    <dbReference type="GeneID" id="39731756"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00322300"/>
    <dbReference type="OMA" id="CITHTEE"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022139">
        <property type="entry name" value="Fam-L/Fam-M-like_plasmodium"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12420">
        <property type="entry name" value="DUF3671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="106"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="230" mass="26953" checksum="67794400280F9BE7" modified="2017-02-15" version="1">MRDYINSNFILNSRCITHTEENFVIEDISTLKKYRTIGKINKLFFFIKISLFTLLIWILLYCENYNYRSWTDKYNLKNKLDLGSKRSLAEGKEVIEPKNEELKVSSSNIQTNLEENNTKVEKLELKEDEKDKKEIIKIENENENVVEIKRESNKKVNSLNLMQKYKSFLRIFNIVSIVILPIMSMTLSIISLSMDDKDNKYVKGSNIVTALYLVLNSILLLDLKSNSNNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUH1</accession>
    <name>A0A1J1GUH1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Vacuolar protein sorting-associated protein 52, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">VPS52</name>
        <name evidence="9" type="ORF">PGAL8A_00235700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">trans-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS52 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527773.1">
        <property type="nucleotide sequence ID" value="XM_028671084.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUH1"/>
    <dbReference type="GeneID" id="39730885"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00235700"/>
    <dbReference type="OMA" id="LINNYYH"/>
    <dbReference type="OrthoDB" id="19482at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000938">
        <property type="term" value="C:GARP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007258">
        <property type="entry name" value="Vps52"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048361">
        <property type="entry name" value="Vps52_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048319">
        <property type="entry name" value="Vps52_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14190">
        <property type="entry name" value="SUPPRESSOR OF ACTIN MUTATIONS 2/VACUOLAR PROTEIN SORTING 52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14190:SF7">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 52 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20655">
        <property type="entry name" value="Vps52_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04129">
        <property type="entry name" value="Vps52_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Vps52 coiled-coil" evidence="7">
        <location>
            <begin position="100"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Vps52 C-terminal" evidence="8">
        <location>
            <begin position="324"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="domain" description="Vps52 C-terminal" evidence="8">
        <location>
            <begin position="847"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="685"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="685"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="697"/>
            <end position="716"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF20655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1048" mass="124820" checksum="50119D72B9A05385" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUI0</accession>
    <name>A0A1J1GUI0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endonuclease/exonuclease/phosphatase family protein, putative</fullName>
            <ecNumber evidence="3">3.1.3.56</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00338500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.56" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528972.1">
        <property type="nucleotide sequence ID" value="XM_028672417.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUI0"/>
    <dbReference type="GeneID" id="39731915"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00338500"/>
    <dbReference type="OMA" id="FNFRVQG"/>
    <dbReference type="OrthoDB" id="7862313at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004445">
        <property type="term" value="F:inositol-polyphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004439">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046985">
        <property type="entry name" value="IP5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000300">
        <property type="entry name" value="IPPc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200">
        <property type="entry name" value="INOSITOL 5-PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11200:SF275">
        <property type="entry name" value="LD06095P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22669">
        <property type="entry name" value="Exo_endo_phos2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00128">
        <property type="entry name" value="IPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inositol polyphosphate-related phosphatase" evidence="2">
        <location>
            <begin position="386"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="724" mass="84971" checksum="A202643E44D71642" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUK2</accession>
    <name>A0A1J1GUK2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Vacuolar protein sorting-associated protein 35</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00337500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Plays a role in vesicular protein sorting.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the VPS35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528962.1">
        <property type="nucleotide sequence ID" value="XM_028672406.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUK2"/>
    <dbReference type="GeneID" id="39731905"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00337500"/>
    <dbReference type="OMA" id="YIRSREY"/>
    <dbReference type="OrthoDB" id="10258141at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030906">
        <property type="term" value="C:retromer, cargo-selective complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.660">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 35, helical subcomplex Vps35-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005378">
        <property type="entry name" value="Vps35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042491">
        <property type="entry name" value="Vps35_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11099:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11099">
        <property type="entry name" value="VACUOLAR SORTING PROTEIN 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03635">
        <property type="entry name" value="Vps35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009375">
        <property type="entry name" value="Retromer_Vps35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR009375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="921" mass="108057" checksum="B26B4E46FAC2D023" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUK9</accession>
    <name>A0A1J1GUK9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Gamma tubulin complex component protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00212600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527544.1">
        <property type="nucleotide sequence ID" value="XM_028670830.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730653"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00212600"/>
    <dbReference type="OMA" id="LEYFCCL"/>
    <dbReference type="OrthoDB" id="775571at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1550"/>
            <end position="1575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1550"/>
            <end position="1569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1676" mass="203721" checksum="2B0708878D14BF0E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUL0</accession>
    <name>A0A1J1GUL0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">IWS1-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00335300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the IWS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528943.1">
        <property type="nucleotide sequence ID" value="XM_028672385.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUL0"/>
    <dbReference type="GeneID" id="39731883"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00335300"/>
    <dbReference type="OrthoDB" id="21124at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.10">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018940">
        <property type="entry name" value="EF-1_beta_acid_region_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051037">
        <property type="entry name" value="RNAPII_TF_IWS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035441">
        <property type="entry name" value="TFIIS/LEDGF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017923">
        <property type="entry name" value="TFIIS_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46010">
        <property type="entry name" value="PROTEIN IWS1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46010:SF1">
        <property type="entry name" value="PROTEIN IWS1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08711">
        <property type="entry name" value="Med26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01182">
        <property type="entry name" value="EF-1_beta_acid"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51319">
        <property type="entry name" value="TFIIS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TFIIS N-terminal" evidence="4">
        <location>
            <begin position="485"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="45"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="227"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="346"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="54"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="73"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="92"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="154"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="173"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="290"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="346"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00037992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="675" mass="80263" checksum="A4145307D35F8117" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUW6</accession>
    <name>A0A1J1GUW6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00249600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527909.1">
        <property type="nucleotide sequence ID" value="XM_028671237.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUW6"/>
    <dbReference type="GeneID" id="39731024"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00249600"/>
    <dbReference type="OrthoDB" id="361577at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="769"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="354"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="699"/>
            <end position="726"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="795" mass="95445" checksum="D029082CFD2C41FB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV64</accession>
    <name>A0A1J1GV64_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DnaJ protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00232800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527744.1">
        <property type="nucleotide sequence ID" value="XM_028671052.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV64"/>
    <dbReference type="GeneID" id="39730855"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00232800"/>
    <dbReference type="OMA" id="WLDLWSK"/>
    <dbReference type="OrthoDB" id="445556at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042977">
        <property type="entry name" value="AtJ6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056453">
        <property type="entry name" value="HTH_DNAJC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44916">
        <property type="entry name" value="CHAPERONE DNAJ-DOMAIN SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44916:SF1">
        <property type="entry name" value="CHAPERONE DNAJ-DOMAIN SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23302">
        <property type="entry name" value="HTH_DNAJC9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="8"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="309" mass="36935" checksum="9DA8CAD5C22BA6C1" modified="2017-02-15" version="1">MKNDKKLSLYDILGIEKNATIKEIAKAYRILALIYHPDKFLANSKKLNNEGKEQKKQAEKEKKGKKKEKDDKSLNSNDNEELTLEKCKEMFLQIQRAYEILRDPDKRKNYDEYGLEDEFSEFKNFFDPKLFHSRIKVEDILNYEKSYKNSEDEKEDLIQFYNKFNGNLENILEYIPFSDENDLDRFVNIFENLFKSKKIKKTSSYSDSLKNINNIIKKYKNLMKKDSKKSKKRKSEQPIDDLVLAIRNNEARRTLKINSLLSNIEKEYGKKNSKKRKQKPPTEEELSEIRKKLEENKKKNMELKKLKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVD9</accession>
    <name>A0A1J1GVD9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00342400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529011.1">
        <property type="nucleotide sequence ID" value="XM_028672461.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVD9"/>
    <dbReference type="GeneID" id="39731954"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00342400"/>
    <dbReference type="OMA" id="VTNENTM"/>
    <dbReference type="OrthoDB" id="392914at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="160"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="26"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="97"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="283" mass="33494" checksum="594740335C415B5B" modified="2017-02-15" version="1">MENINNSNNKKEERTPNRKNRKKNGRNRDKKNNTVHDKGNIEKLEKNNELNYRDEKDKDLSNKLDENNDRTKNSEENSKDFIKVEYTSSNDKGIINGKDENDIKSEDLKNPLEDNNLNENDNSYEKIKNKGNSSSNAEIVVEPLAFEEKLKMWKGTVDSLKEKKEDEKKMQEQRQIQIENIKLVHSIKKEEKVLQQMYLEQLKKDEELAKQLEQELNAEIRNELSKIEQDDFKLATIIQNSFDSEQTQQINNENNEQLKSKKLSKIKLLKEKFRNFFKKKSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVJ9</accession>
    <name>A0A1J1GVJ9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)</fullName>
            <ecNumber evidence="4">5.4.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00414000</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23536"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="5.4.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.2" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529364.1">
        <property type="nucleotide sequence ID" value="XM_028672852.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVJ9"/>
    <dbReference type="GeneID" id="39732670"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00414000"/>
    <dbReference type="OMA" id="DGMHGAG"/>
    <dbReference type="OrthoDB" id="2291at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004614">
        <property type="term" value="F:phosphoglucomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.120.10">
        <property type="entry name" value="Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.50">
        <property type="entry name" value="Alpha-D-phosphohexomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045244">
        <property type="entry name" value="PGM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22573:SF2">
        <property type="entry name" value="PHOSPHOGLUCOMUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22573">
        <property type="entry name" value="PHOSPHOHEXOMUTASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24947">
        <property type="entry name" value="PGM1_C_vert_fung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="Phosphoglucomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="Phosphoglucomutase, first 3 domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="9">
        <location>
            <begin position="41"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="10">
        <location>
            <begin position="385"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="302"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG96560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="649" mass="75454" checksum="DB71FD7D7ACC4A68" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVT6</accession>
    <name>A0A1J1GVT6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00424600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529470.1">
        <property type="nucleotide sequence ID" value="XM_028672970.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVT6"/>
    <dbReference type="GeneID" id="39732778"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00424600"/>
    <dbReference type="OrthoDB" id="376327at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="222"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="168"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="260" mass="31198" checksum="D94AE27595909C49" modified="2017-02-15" version="1">MEVTKTFVPLIIGSYGLCLSSYLIYKKKKKNNWQKINGYIDHVALKYTKNFLQEAFYLNVKYYFHINNEKIENSKEYKIWVNIFKNKSTQNIVTNGYTQNIFDQISKEKNIHISYNPNNFRESEPLIYIYENDILLKYKLLYKIKSKLINIKMYFSKNSDTNKAKNFLNKETEYKKELEEKNKIEKANTENNTLNLEDTNENFKLSDYKKKLIDSYDINNKFPIYMFSCSLFLILSFFLKKRIIFVSKELSQKNISKNVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVV3</accession>
    <name>A0A1J1GVV3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Oxidation resistance protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00255200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the OXR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527960.1">
        <property type="nucleotide sequence ID" value="XM_028671293.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVV3"/>
    <dbReference type="GeneID" id="39731080"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00255200"/>
    <dbReference type="OMA" id="DFIYVYP"/>
    <dbReference type="OrthoDB" id="289228at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006571">
        <property type="entry name" value="TLDc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23354:SF62">
        <property type="entry name" value="MUSTARD, ISOFORM V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23354">
        <property type="entry name" value="NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07534">
        <property type="entry name" value="TLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00584">
        <property type="entry name" value="TLDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51886">
        <property type="entry name" value="TLDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TLDc" evidence="5">
        <location>
            <begin position="483"/>
            <end position="673"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="730" mass="85903" checksum="D440AF5978F5C13F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVY7</accession>
    <name>A0A1J1GVY7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">THH1/TOM1/TOM3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00421000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the plant tobamovirus multiplication TOM1 protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529434.1">
        <property type="nucleotide sequence ID" value="XM_028672930.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVY7"/>
    <dbReference type="GeneID" id="39732742"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00421000"/>
    <dbReference type="OMA" id="LFWSQVY"/>
    <dbReference type="OrthoDB" id="19798at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040226">
        <property type="entry name" value="THH1/TOM1/TOM3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009457">
        <property type="entry name" value="THH1/TOM1/TOM3_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31142:SF3">
        <property type="entry name" value="THH1_TOM1_TOM3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31142">
        <property type="entry name" value="TOBAMOVIRUS MULTIPLICATION PROTEIN 1-LIKE ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06454">
        <property type="entry name" value="THH1_TOM1-3_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="90"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="203"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="THH1/TOM1/TOM3" evidence="7">
        <location>
            <begin position="93"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="306" mass="36153" checksum="7A6F2A1A352775BF" modified="2017-02-15" version="1">MTIGIYLLIFLIFFYVYLSCLLYNLLIRNKKISPISSANLTGEKTRLFLFYFLFFCHISRIISLIILTFLDIKYNSVDYNTLLLFPNFYFYLILLKTFPTYFFLSSFTIIIVFWSQVYYASILVSFPYLQPLYIFLNVLVYSINIVLASLTYFMKTFIDYISYNYILESIIDYLIAIGFIYYGVKVTKKLKEKSKGISRKKNIIKRILALSVILFIILSLKGLYSFWCFFSGSNFYNSYLDLPTSDAIIYFISECIPSFLIISTFQPNKEKNTLNIQYTTPLCSDTFDPYNLKFKKTKQNMIKENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVZ0</accession>
    <name>A0A1J1GVZ0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Beta'-coat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">SEC27</name>
        <name evidence="18" type="ORF">PGAL8A_00418400</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasmic vesicle</location>
            <location evidence="2">COPI-coated vesicle membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the WD repeat COPB2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529407.1">
        <property type="nucleotide sequence ID" value="XM_028672901.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVZ0"/>
    <dbReference type="GeneID" id="39732715"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00418400"/>
    <dbReference type="OMA" id="KSYGQCV"/>
    <dbReference type="OrthoDB" id="2150324at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22947">
        <property type="entry name" value="Coatomer_WDAD_beta-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000016">
        <property type="entry name" value="Coatomer alpha subunit, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.470:FF:000001">
        <property type="entry name" value="Coatomer subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006692">
        <property type="entry name" value="Beta-prop_COPA/B_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050844">
        <property type="entry name" value="Coatomer_complex_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016453">
        <property type="entry name" value="COPB2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056176">
        <property type="entry name" value="TPR_COPA_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19876">
        <property type="entry name" value="COATOMER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19876:SF2">
        <property type="entry name" value="COATOMER SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04053">
        <property type="entry name" value="B-prop_COPA_B_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23953">
        <property type="entry name" value="TPR_COPA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005567">
        <property type="entry name" value="Coatomer_beta'_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="8" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <keyword evidence="6 15" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="15">
        <location>
            <begin position="95"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="15">
        <location>
            <begin position="138"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="15">
        <location>
            <begin position="186"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="15">
        <location>
            <begin position="230"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="COPA/B second beta-propeller" evidence="16">
        <location>
            <begin position="324"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="domain" description="COPA/B TPR" evidence="17">
        <location>
            <begin position="609"/>
            <end position="796"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF23953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="CRG96603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1027" mass="120317" checksum="E241C07AD6D7A5DE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW31</accession>
    <name>A0A1J1GW31_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fam-i protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00270900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000040">
        <property type="protein sequence ID" value="CRG95508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528317.1">
        <property type="nucleotide sequence ID" value="XM_028671690.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW31"/>
    <dbReference type="GeneID" id="39731240"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00270900"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="121"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="178"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="254" mass="30283" checksum="D0C6CC6DFB7A3CA4" modified="2017-02-15" version="1">MDLNPSDPININSNKRLNEGDSTAGFAHREIKNETVTIRENPLQDDLNSRDAIQNPSKDINLDSVTSKNLLHKKSLSIFQLVIIFIFFLRFKKTYSLKLKAKNEMNVRLQKILNNCDKKMKDDLENEMLEEKKKMEDGQKKLLKKKKEMEHREKGVLRHKEEWERTLKEKHVCHESMLKVLEGRKKKITEEGEKWEKRMIIEKMELEKKMLKNKEEGEERMLKVIEKFEKKMLKEKESGWLIKGFIKLFGNKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW72</accession>
    <name>A0A1J1GW72_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protease, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00426300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529487.1">
        <property type="nucleotide sequence ID" value="XM_028672990.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW72"/>
    <dbReference type="GeneID" id="39732795"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00426300"/>
    <dbReference type="OMA" id="MHIHYAV"/>
    <dbReference type="OrthoDB" id="361580at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004175">
        <property type="term" value="F:endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080120">
        <property type="term" value="P:CAAX-box protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1/LyrA-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43592">
        <property type="entry name" value="CAAX AMINO TERMINAL PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43592:SF15">
        <property type="entry name" value="CAAX AMINO TERMINAL PROTEASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011977980" evidence="2">
        <location>
            <begin position="19"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="287"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="360"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="385"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="408"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="CAAX prenyl protease 2/Lysostaphin resistance protein A-like" evidence="3">
        <location>
            <begin position="334"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="429" mass="51819" checksum="774E597B16BDCA9B" modified="2017-02-15" version="1">MMVKLFCFSIFLWLCVKSYNIKKTQIITNRYGIVNKNGVNYNVLKKKKFYNYSKLKIYSSKEKDSGNGKYKNIIRKYIFNFCLKNSIYFTNSLEYIKNILRKTKEMLFKNSLKKQIFISVSFFFIHFYLLSKHFLILFPYQLIPNHSNILMSLDLNNTLFILTSLYFLKDIKKNIEKFKQRLNFKRFKLELQENKKKNILSISVLLIASYILSGYVSLYTENILNFLKVFKFSVSDNIIKSLQILSGHFMWVVCSIIIIRRLLYPYFKHNKSNLNFLYKESWYFKVIYGYMFSHFIFNIIDVFNNIILNYFHNNEIHFDNSIDEIVNEKELISTILCIISPCFSAPFFEEYIYRFFVLKSLNLFMNIHYSVIFSSLFFAIHHLNIFNLLPLFFLSFFWSYIYIYTDNILVTMLIHSFWNLYVFLTSLYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWB1</accession>
    <name>A0A1J1GWB1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00006700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528112.1">
        <property type="nucleotide sequence ID" value="XM_028671462.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWB1"/>
    <dbReference type="GeneID" id="39728589"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00006700"/>
    <dbReference type="OrthoDB" id="10396517at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="177"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="466" mass="54150" checksum="4B367917150BD6F8" modified="2017-02-15" version="1">MSSNNSYSSCMFAKNDYDDTYSNEEKIKKRNLKECLKNEPNDFNLQHNLKKIRKKKLSKLKNYNNNQIKNYKVKWSNRMKWTPKMLEIFEESVFYFLEQQKKIKDSTYEPTPCRILSYMHKKFEDLEEKNLNDIKNMQNLSRLHVGSKLQKFLLKLKKLGIKENIKKKNVSNEGSVDTYYSNDNNDSNNNTNSDYYYQANINKSFNANNMSHSCSKSNASNPVDNFNGSNNDISESLNNKSYIDTENFNNNLYSNQIVNDSKYFTNYDTINSYFIYASNYDNSNIPNKITTSVVHNDSSNDLINGNRNIPFVNEINLTNKTNPNNTLSLNNPVVLTNNSFEVSPFSLINNNNNSNNNKSFNNIGDTFYSFNSTNLNGINNDMNELQIVELLHLVVKDFSLLNDNTKAQILFKLAKQLLNMAEEIFTNNFTNYTSLEDENILNFQCRSNINSLMPLKMLCQINNLKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWB3</accession>
    <name>A0A1J1GWB3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00441400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529636.1">
        <property type="nucleotide sequence ID" value="XM_028673155.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWB3"/>
    <dbReference type="GeneID" id="39732947"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00441400"/>
    <dbReference type="OMA" id="PQFYNGE"/>
    <dbReference type="OrthoDB" id="384256at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="113" mass="13275" checksum="37601C8D6B1B88A9" modified="2017-02-15" version="1">MIAPEFFNGEIVLDLDSTIFKIQSEKIINFYEQTVYNYLYNDDNTKNDEKANITTAYRVDEKIKKLKKERNKKKGLSFQTLSLLVTFSFIYFSCKGIIDHFKLNGNQNIKKSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWH2</accession>
    <name>A0A1J1GWH2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00447800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529700.1">
        <property type="nucleotide sequence ID" value="XM_028673226.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWH2"/>
    <dbReference type="GeneID" id="39733011"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00447800"/>
    <dbReference type="OMA" id="ILEFFPW"/>
    <dbReference type="OrthoDB" id="371213at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="189" mass="22579" checksum="A5AB264D0C1B3DB0" modified="2017-02-15" version="1">MNRICTTLVVVKILEFFPWIDDLFKLFYLNRLWRNTILDVIKNTNFLIGKTTMRLKNKNFILLILKYINGSHKTNQNIIDRFSYLTCENFKISSFPNVLGLIIVSSNLNPPFFNYIHNIFPNLIYLKLIIKSPVCIPLLKNFCFYSKNLKYIIICFVNNELNEEYKDKLKKSINNFLFHWHINVKLITE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWH7</accession>
    <name>A0A1J1GWH7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00419500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529419.1">
        <property type="nucleotide sequence ID" value="XM_028672914.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWH7"/>
    <dbReference type="GeneID" id="39732727"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00419500"/>
    <dbReference type="OrthoDB" id="372861at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="103" mass="12682" checksum="B7D9D4FF580BCBFA" modified="2017-02-15" version="1">MSEELKNIEKEYKNFYEKIEYIDENTIYMHIKIDDNKDKISNLKDNYLNLYIKFHSNYFEVLNENLNGEKKFDCMEQIFNTFCPFTFKKYIIKNIKHKLNSDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWY7</accession>
    <name>A0A1J1GWY7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Gametocyte associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00273200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528344.1">
        <property type="nucleotide sequence ID" value="XM_028671719.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWY7"/>
    <dbReference type="GeneID" id="39731264"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00273200"/>
    <dbReference type="OrthoDB" id="385784at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3030.10">
        <property type="entry name" value="Gametocyte protein Pfg27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036469">
        <property type="entry name" value="Pfg27_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="250" mass="28993" checksum="06D3FFE9BEC45099" modified="2017-02-15" version="1">MKNLKIFYFFNIFFLTSLPIILLFNTNIFEGLGEERLQRKYPKLWNVIERNLSQASASGTSTQRDSDAIRKRLNAICDSLHMGYMDITHWLTKPNDPLFSSYVNDGLKIADTIFLRVKSLLSNPSYNLIRHETARAQERNALVTSLGRSRRSILYMIKIFEMENEITKDLLHIMVGKTQNELKILIENNDRTSGEIKSELLKRNLHLPDVHLERMILRINWRAHDLALEGGILDDPIPEPLDCYPSDFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX74</accession>
    <name>A0A1J1GX74_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Replication factor C subunit 4, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00462400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the activator 1 small subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529847.1">
        <property type="nucleotide sequence ID" value="XM_028673390.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX74"/>
    <dbReference type="GeneID" id="39733157"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00462400"/>
    <dbReference type="OMA" id="SCNYSSQ"/>
    <dbReference type="OrthoDB" id="4199794at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005663">
        <property type="term" value="C:DNA replication factor C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18140">
        <property type="entry name" value="HLD_clamp_RFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000952">
        <property type="entry name" value="Replication factor C subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000012">
        <property type="entry name" value="Replication factor C subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050238">
        <property type="entry name" value="DNA_Rep/Repair_Clamp_Loader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013748">
        <property type="entry name" value="Rep_factorC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047854">
        <property type="entry name" value="RFC_lid"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001679">
        <property type="entry name" value="PRK00440.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669">
        <property type="entry name" value="REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669:SF5">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08542">
        <property type="entry name" value="Rep_fac_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="48"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="336" mass="37611" checksum="7479089EE134A46C" modified="2017-02-15" version="1">MEEESFKNRLLKRNIDIWIEKYRPEYLDEVVGNPFVINTLKSIISSGNMPNLLLAGAPGTGKTTSILCLASEMLGDLAKKAVLELNASDDRGINVIRDRIKSFAKEIISLPPGRHKIIILDEVDSMTTAAQQSLRRIMELYSDTTRFALACNQSEKIIDALQSRCAIIRYFKLSDDQVLKRILKICDLENIKYTDDGLEALLFIADGDLRKAVNCLQSTHAGLEIINKENVLNICDIPSPERIEKLLKHCINSEWKKAHEVAYEMISEGHTPFDVALTSSNVLRRYDLGSESVQVEFLKIGAMACNTMASGLATAIQLDKLLADWCIAAKTFRTKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXE5</accession>
    <name>A0A1J1GXE5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Prefoldin subunit 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00288500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prefoldin subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528496.1">
        <property type="nucleotide sequence ID" value="XM_028671889.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXE5"/>
    <dbReference type="GeneID" id="39731418"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00288500"/>
    <dbReference type="OMA" id="LGQMEDV"/>
    <dbReference type="OrthoDB" id="29646at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23163">
        <property type="entry name" value="Prefoldin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.370:FF:000016">
        <property type="entry name" value="Prefoldin subunit 2, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027235">
        <property type="entry name" value="PFD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002777">
        <property type="entry name" value="PFD_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13303">
        <property type="entry name" value="PREFOLDIN SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01920">
        <property type="entry name" value="Prefoldin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="22"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="86"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="146" mass="16941" checksum="9A13DE91660DFEE6" modified="2017-02-15" version="1">MENKKDIQITKLDEQSEAKSTYEQIEKDRVQLVSKIEELYQDVVEHKLVLEALENVPSDRRCYRMVGEILVERTVGEIKPALIDHKNKVEQIISECQKKLDEKNNEISKFMKNSQTLNIPSSLISKKSLENNNSFNDKDKKSGLTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXI3</accession>
    <name>A0A1J1GXI3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00485300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530076.1">
        <property type="nucleotide sequence ID" value="XM_028673645.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXI3"/>
    <dbReference type="GeneID" id="39733386"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00485300"/>
    <dbReference type="OMA" id="INKYTSW"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="69"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="320"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="7"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="69"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="82"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="95"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="109"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="136"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="146"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="176"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="193"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="239"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="320"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="342" mass="41417" checksum="04628E35E89E2C7C" modified="2017-02-15" version="1">MSSRSNMFQILRQEDKIKRKAKQLKEEQLKKENEKKDMNNFTFDINKYSSWADFIDDYDEFFYEVDKLKDLGKSKTSDQNDKKKKKEKKKKLESEESNEEEKEEEKEKEEEKEKEEKDKEEKEKEHKDRENKNKNKNSNNNSNNLNKKKQNTKKKSSKKDREMKNFENILLEFTKNDINNQDNNPNEINEENNDSKEKIEQNSNKNEDDNIIENDNQDKLKKKKKKKKKKKKKKKKEKKKNDEIDDSLKREDVNEKETLDKLNQTLNLDNENNNDEKLNDNTIPVNEKLKLLLNKNSKKKKKREKIDEIIAIVEKEENIKQKQKEKLKQKEKQKLKLKQKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY71</accession>
    <name>A0A1J1GY71_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PUB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00500400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530233.1">
        <property type="nucleotide sequence ID" value="XM_028673818.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY71"/>
    <dbReference type="GeneID" id="39733537"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00500400"/>
    <dbReference type="OrthoDB" id="440781at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012506">
        <property type="term" value="C:vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09212">
        <property type="entry name" value="PUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036339">
        <property type="entry name" value="PUB-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018997">
        <property type="entry name" value="PUB_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46467">
        <property type="entry name" value="TETHER CONTAINING UBX DOMAIN FOR GLUT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46467:SF1">
        <property type="entry name" value="TETHER CONTAINING UBX DOMAIN FOR GLUT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09409">
        <property type="entry name" value="PUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143503">
        <property type="entry name" value="PUG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PUB" evidence="1">
        <location>
            <begin position="250"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="558" mass="65834" checksum="63195A3C50AA3048" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYF6</accession>
    <name>A0A1J1GYF6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00517500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530403.1">
        <property type="nucleotide sequence ID" value="XM_028674007.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYF6"/>
    <dbReference type="GeneID" id="39733708"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00517500"/>
    <dbReference type="OMA" id="VICKVCY"/>
    <dbReference type="OrthoDB" id="370932at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1050.10">
        <property type="entry name" value="At2g23090-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039713">
        <property type="entry name" value="At2g23090-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039438">
        <property type="entry name" value="At2g23090-like_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007513">
        <property type="entry name" value="SERF-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026939">
        <property type="entry name" value="ZNF706/At2g23090_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33788">
        <property type="entry name" value="OS07G0114300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33788:SF1">
        <property type="entry name" value="ZINC-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04419">
        <property type="entry name" value="SERF-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12907">
        <property type="entry name" value="zf-met2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118359">
        <property type="entry name" value="Expressed protein At2g23090/F21P24.15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Small EDRK-rich factor-like N-terminal" evidence="2">
        <location>
            <begin position="4"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="At2g23090-like zinc-binding" evidence="3">
        <location>
            <begin position="39"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="78" mass="8828" checksum="A5EEBB91EBF0CEB0" modified="2017-02-15" version="1">MGKGSNACKRNQARERKNVEVKGGKSQLKANKEALNVTCKVCYTVFMKTQSIAQLAEHAENKHNKDVKECFPQKFEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYI8</accession>
    <name>A0A1J1GYI8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00520400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530429.1">
        <property type="nucleotide sequence ID" value="XM_028674036.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYI8"/>
    <dbReference type="GeneID" id="39733737"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00520400"/>
    <dbReference type="OMA" id="PICFHIK"/>
    <dbReference type="OrthoDB" id="446277at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036065">
        <property type="entry name" value="BolA-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82657">
        <property type="entry name" value="BolA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="119" mass="14379" checksum="672914E7CD27F84C" modified="2017-02-15" version="1">MIIKIYNFNLIKKNYAHKFASPDCPNLINIKKLIYEKLKPICFHIKQDYTMGHHVHDMHFYGILCSPLFENKSYKEMNSMVEKLMSEINLAGRVKLHCQPPSRFNKMKKHIRWRWNLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYL9</accession>
    <name>A0A1J1GYL9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ADP-ribosylation factor, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00512500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530353.1">
        <property type="nucleotide sequence ID" value="XM_028673951.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYL9"/>
    <dbReference type="GeneID" id="39733658"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00512500"/>
    <dbReference type="OMA" id="EFIRIIY"/>
    <dbReference type="OrthoDB" id="442317at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="19"/>
            <end position="26"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="133"/>
            <end position="136"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="201" mass="23834" checksum="40E6B937086DA514" modified="2017-02-15" version="1">MFLRFFSLKPTRKNLIIFGLPSSGKTSIIYFFKLGYLITTVRTFLINEECFTITLKTDKDNFEEKKFKVKFFEVGSDCSFNLIKEYSEISNDLIYIVDSSQKGSLREARDDFIRIIYDFRFIYRRCKFLIFLNKQDSNGCLKSEEIINYFSLPKELLFRCKFISCSTLSGEGLKEGLDWLLNSNVFLNKTDVNYENKRIYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYS9</accession>
    <name>A0A1J1GYS9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">40S ribosomal protein S27, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPS27</name>
        <name evidence="6" type="ORF">PGAL8A_00504400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic ribosomal protein eS27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530272.1">
        <property type="nucleotide sequence ID" value="XM_028673861.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYS9"/>
    <dbReference type="GeneID" id="39733577"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00504400"/>
    <dbReference type="OMA" id="IRSCARI"/>
    <dbReference type="OrthoDB" id="5567124at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.100:FF:000001">
        <property type="entry name" value="40S ribosomal protein S27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.100">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00371">
        <property type="entry name" value="Ribosomal_eS27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000592">
        <property type="entry name" value="Ribosomal_eS27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023407">
        <property type="entry name" value="Ribosomal_eS27_Zn-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11594">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01667">
        <property type="entry name" value="Ribosomal_S27e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="82" mass="9128" checksum="9ED85E35F0CD27CC" modified="2017-02-15" version="1">MNVDLLNPDPVEESKKHKLKRLIPSPNSYFMDVKCPGCLQITTLFSHAQNVVLCGSCNIMLCQPTGGKCKLTEGCSFRKKIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ73</accession>
    <name>A0A1J1GZ73_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Autophagy-related protein 3, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ATG3</name>
        <name evidence="8" type="ORF">PGAL8A_00418200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATG3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529405.1">
        <property type="nucleotide sequence ID" value="XM_028672898.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ73"/>
    <dbReference type="GeneID" id="39732713"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00418200"/>
    <dbReference type="OMA" id="KWCKAIS"/>
    <dbReference type="OrthoDB" id="1584384at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019776">
        <property type="term" value="F:Atg8-family ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061723">
        <property type="term" value="P:glycophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044804">
        <property type="term" value="P:nucleophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1460.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007135">
        <property type="entry name" value="Atg3/Atg10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12866">
        <property type="entry name" value="UBIQUITIN-LIKE-CONJUGATING ENZYME ATG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12866:SF2">
        <property type="entry name" value="UBIQUITIN-LIKE-CONJUGATING ENZYME ATG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03987">
        <property type="entry name" value="Autophagy_act_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0072">Autophagy</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="307" mass="36409" checksum="A811ADCFFBDB194C" modified="2017-02-15" version="1">MSDQLNVKHKIADTCRKIYSYFKPISNTSSFIKNGTLTPEEFVDAGDFLVHKFKTWEWQEADKDRNVSYLPEGKQFLITRNAPCKQRLKELNYITHDLKIVENEWLHPNYEEDNNAIDINEYPHNLPFSIRKSIKEEKEYDNDDDVIDINNFDIEDSIFNENDPASVDNPSYYYNNIRNDNTMKIRTYDISITYDKYYQTPRIWLFGYDENGNPLKPEEIFEDVLADYSYKTVTYDPHPCTGIMTASIHPCRHADAMLKIIKNWINDKKEPRHDLYLLFLLKFVSGVIPSIEYDFTTDIEIPRDYKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ96</accession>
    <name>A0A1J1GZ96_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Debranching enzyme-associated ribonuclease, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">DRN1</name>
        <name evidence="6" type="ORF">PGAL8A_00534600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CWF19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530569.1">
        <property type="nucleotide sequence ID" value="XM_028674191.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ96"/>
    <dbReference type="GeneID" id="39733879"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00534600"/>
    <dbReference type="OMA" id="CKCIFTD"/>
    <dbReference type="OrthoDB" id="2113965at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040194">
        <property type="entry name" value="Cwf19-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006768">
        <property type="entry name" value="Cwf19-like_C_dom-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006767">
        <property type="entry name" value="Cwf19-like_C_dom-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12072">
        <property type="entry name" value="CWF19, CELL CYCLE CONTROL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12072:SF5">
        <property type="entry name" value="CWF19-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04677">
        <property type="entry name" value="CwfJ_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04676">
        <property type="entry name" value="CwfJ_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cwf19-like C-terminal" evidence="5">
        <location>
            <begin position="193"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="Cwf19-like protein C-terminal" evidence="4">
        <location>
            <begin position="335"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="78"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="27"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="78"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="429" mass="51940" checksum="6116E2D0F3497F0C" modified="2017-02-15" version="1">MSNIDEFYEYAKNNFLSFLKKNNINSKNEEKIEIKENKRKIKGINKKDLSDIEKLKNEELKDKENYDEKYKNFILKKKEKKKRKYRKSSSSMSSYNEKNDSRNKKKKKKRKHEEYKKTCREEKKKYKEREIKSYINDPISDDDKNNPENENLSLLHQNENDVKTHFPENSKLKIKLEKIIVEKKNSMLLKNSLNKNLVDCKYCIDSNSFDKINKLNIVSISNRSYICYYNYKNIFLKDQLFISPIEHTTSITNTDFETIRDIRNHMKSLIAMLEPNNQTCIFIEFNNCFNSNIELISMRKTKHTYINCYIIPMELLEKAKIYFKKNMEDINSLYRENKQLIITDNKYAPYNIIPKKIPYVSINFSLVETYIQVIENNYDYINMCKCIFTDLFKKDKLYKYFNNFQQYVNTVEQFKSSYEKYDWTNYINK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZA7</accession>
    <name>A0A1J1GZA7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00033900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530701.1">
        <property type="nucleotide sequence ID" value="XM_028674338.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZA7"/>
    <dbReference type="GeneID" id="39728862"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00033900"/>
    <dbReference type="OMA" id="YNPYFCK"/>
    <dbReference type="OrthoDB" id="376677at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="753" mass="92025" checksum="3EF98D42E59BEA3A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZD3</accession>
    <name>A0A1J1GZD3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ORC1/DEAH AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00024400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDC6/cdc18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530609.1">
        <property type="nucleotide sequence ID" value="XM_028674236.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZD3"/>
    <dbReference type="GeneID" id="39728767"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00024400"/>
    <dbReference type="OrthoDB" id="1926878at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049945">
        <property type="entry name" value="AAA_22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050311">
        <property type="entry name" value="ORC1/CDC6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763:SF26">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 6 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13401">
        <property type="entry name" value="AAA_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ORC1/DEAH AAA+ ATPase" evidence="4">
        <location>
            <begin position="187"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="494"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="101"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="498"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="518"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="870" mass="102536" checksum="27CCABB740562AD0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZD8</accession>
    <name>A0A1J1GZD8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">DDX23</name>
        <name evidence="15" type="ORF">PGAL8A_00040100</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the DEAD box helicase family. DDX23/PRP28 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530763.1">
        <property type="nucleotide sequence ID" value="XM_028674406.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZD8"/>
    <dbReference type="SMR" id="A0A1J1GZD8"/>
    <dbReference type="GeneID" id="39728925"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00040100"/>
    <dbReference type="OMA" id="ARDIKHM"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17945">
        <property type="entry name" value="DEADc_DDX23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057479">
        <property type="entry name" value="PRP28/DDX23-like_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25430">
        <property type="entry name" value="DDX23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 15" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="14">
        <location>
            <begin position="481"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="512"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="741"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="123"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="209"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="10">
        <location>
            <begin position="481"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG97964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="906" mass="104905" checksum="32262C8C1FE41A3E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H022</accession>
    <name>A0A1J1H022_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rhoptry-associated protein 2/3, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">RAP2/3</name>
        <name evidence="2" type="ORF">PGAL8A_00022800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H022"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00022800"/>
    <dbReference type="OMA" id="HFFFSHF"/>
    <dbReference type="OrthoDB" id="370145at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012000783" evidence="1">
        <location>
            <begin position="22"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="393" mass="46288" checksum="8D2B47CCA9DC0291" modified="2017-02-15" version="1">MKKLFFLTIIFSFIFQKAIKGQTCIKSLSSFNIRDLTIANFLHAHNEDYEVLGKWIHFFFSHFDNDKDLMKFMSTFDIKSLDLLDRSCIKRALTIYLLHYYSNTIKKMSNDGTYVSYFKNIFEGYSSLTSEFIRVIADRHYINLLDTIIVNKEKTKIRSAIFPLKTFIKASKKGDYSLEENKAKMNFSDANNFKFKFLDNKKLVTSVNEAKAIQDFNLLGMLGVKDLYYNSDITRSVEGVFYVFNKNKRLGLRRRSGKYDIYSKEGNSKVFGNCIKDNHFYHGSVDDLATFFFSNMKMKMVKGHKKFLDDFELALNKKTYKMPKLKGFRFIKQLFSRKNFKNFIKLYANHVSTELAFLTQDFQNLFDITLQCQIKNINRAGTIYYILKYRNAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0B3</accession>
    <name>A0A1J1H0B3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00043400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530800.1">
        <property type="nucleotide sequence ID" value="XM_028674449.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0B3"/>
    <dbReference type="GeneID" id="39728959"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00043400"/>
    <dbReference type="OMA" id="NNMDYSN"/>
    <dbReference type="OrthoDB" id="371620at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG98003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="139" mass="16407" checksum="08550AEE630181D2" modified="2017-02-15" version="1">MLIFKRHFSRFINNNSKKTARKNFHKNLTQYKNTTNNVTNQNENNKLSRGGGLLNTFYESFIYGCGFFLSNRLLDQIFGPRHYDTYNSNTDNYVDENQNNYMDQSQSNYSNENFLNNDSTIDDDDFKQDIGLDDDTFEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0C1</accession>
    <name>A0A1J1H0C1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Large ribosomal subunit assembling factor, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00063200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530990.1">
        <property type="nucleotide sequence ID" value="XM_028674660.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0C1"/>
    <dbReference type="GeneID" id="39729157"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00063200"/>
    <dbReference type="OrthoDB" id="2196187at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027312">
        <property type="entry name" value="Sda1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012977">
        <property type="entry name" value="SDA1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12730">
        <property type="entry name" value="HSDA/SDA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12730:SF0">
        <property type="entry name" value="PROTEIN SDA1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08158">
        <property type="entry name" value="SDA1_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SDA1 N-terminal" evidence="2">
        <location>
            <begin position="311"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="656"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="867"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="925"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="656"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="748"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="768"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="874"/>
            <end position="891"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="945" mass="113527" checksum="3E45335FA2ECFB1A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0G5</accession>
    <name>A0A1J1H0G5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Calcyclin binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00459800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529821.1">
        <property type="nucleotide sequence ID" value="XM_028673361.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0G5"/>
    <dbReference type="GeneID" id="39733131"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00459800"/>
    <dbReference type="OMA" id="KNTRWDY"/>
    <dbReference type="OrthoDB" id="164025at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044548">
        <property type="term" value="F:S100 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06468">
        <property type="entry name" value="p23_CacyBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.790:FF:000040">
        <property type="entry name" value="Calcyclin binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052289">
        <property type="entry name" value="Calcyclin-binding_UBL-bridge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037893">
        <property type="entry name" value="CS_CacyBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007699">
        <property type="entry name" value="SGS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13164:SF3">
        <property type="entry name" value="CALCYCLIN-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13164">
        <property type="entry name" value="CALICYLIN BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51048">
        <property type="entry name" value="SGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="2">
        <location>
            <begin position="72"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="SGS" evidence="1">
        <location>
            <begin position="150"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="227" mass="26522" checksum="4023596B6149C33B" modified="2017-02-15" version="1">MDSKRIDDLNDDITELNKLLSLTTRENVKKKINHCIENINAEIIKLKTEGSQSPNKINDVNLPLDDSNISYNSVQSFAWNQEGNKVTIFLTVKNVHNIEKEKIVTEFDERSFEIKMHDVDKKNYRFCVKKLHEKILPKKCSIKVKKDSVHVNLIKQDNKYWDNLHFKESPMSKIKAPKIDEQTEPSAMLMNMMKQLYQEGDSEMKRTIAKAWCEANEKKSDFSVPNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0N2</accession>
    <name>A0A1J1H0N2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Protein transport protein Sec24B, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SEC24B</name>
        <name evidence="9" type="ORF">PGAL8A_00055800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530920.1">
        <property type="nucleotide sequence ID" value="XM_028674582.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729083"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00055800"/>
    <dbReference type="OrthoDB" id="49016at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030127">
        <property type="term" value="C:COPII vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090110">
        <property type="term" value="P:COPII-coated vesicle cargo loading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1670">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.730">
        <property type="entry name" value="Sec23/Sec24 helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012990">
        <property type="entry name" value="Beta-sandwich_Sec23_24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036180">
        <property type="entry name" value="Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006900">
        <property type="entry name" value="Sec23/24_helical_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036175">
        <property type="entry name" value="Sec23/24_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006896">
        <property type="entry name" value="Sec23/24_trunk_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050550">
        <property type="entry name" value="SEC23_SEC24_subfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036174">
        <property type="entry name" value="Znf_Sec23_Sec24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13803">
        <property type="entry name" value="SEC24-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13803:SF39">
        <property type="entry name" value="SECRETORY 24AB, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08033">
        <property type="entry name" value="Sec23_BS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04815">
        <property type="entry name" value="Sec23_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04811">
        <property type="entry name" value="Sec23_trunk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82754">
        <property type="entry name" value="C-terminal, gelsolin-like domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81811">
        <property type="entry name" value="Helical domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82919">
        <property type="entry name" value="Zn-finger domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Sec23/Sec24 trunk" evidence="6">
        <location>
            <begin position="1364"/>
            <end position="1592"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 beta-sandwich" evidence="8">
        <location>
            <begin position="1604"/>
            <end position="1690"/>
        </location>
    </feature>
    <feature type="domain" description="Sec23/Sec24 helical" evidence="7">
        <location>
            <begin position="1702"/>
            <end position="1799"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="258"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1004"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1004"/>
            <end position="1027"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG98123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1959" mass="228555" checksum="5118A59264928AB6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H181</accession>
    <name>A0A1J1H181_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L3, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPL3</name>
        <name evidence="5" type="ORF">PGAL8A_00487000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530093.1">
        <property type="nucleotide sequence ID" value="XM_028673663.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H181"/>
    <dbReference type="GeneID" id="39733403"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00487000"/>
    <dbReference type="OMA" id="QRTEYNK"/>
    <dbReference type="OrthoDB" id="1611972at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000079">
        <property type="entry name" value="60S ribosomal protein L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1430.10:FF:000001">
        <property type="entry name" value="60S ribosomal protein L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.960.10:FF:000001">
        <property type="entry name" value="60S ribosomal protein L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.960.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000351">
        <property type="entry name" value="Ribosomal protein L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.960.10">
        <property type="entry name" value="Ribosomal protein L3, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045077">
        <property type="entry name" value="L3_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044892">
        <property type="entry name" value="Ribosomal_L3_dom_3_arc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000597">
        <property type="entry name" value="Ribosomal_uL3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019926">
        <property type="entry name" value="Ribosomal_uL3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11363">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11363:SF5">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00297">
        <property type="entry name" value="Ribosomal_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00474">
        <property type="entry name" value="RIBOSOMAL_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="386" mass="44365" checksum="BE5F2C0C4529C327" modified="2017-02-15" version="1">MSHRKFERPRHGSLGFLPRKRCKRLRGKIRSFPKDDKEKPPHFTAFMGYKAGMTHIVREVDKPGSKLHKKEIVEACTIIECAPMVVVGIVGYRETPKGLRILSTVWANHVSDEFRRRYYKNWYKSEKKAFTKSLNVPESTKECLLKRIEKYCTVLRAICHTQPSKTPLRMKKAHIMEIQINGGTMKEKIEFVKELLEKNLPVSTVFNENEMIDVISVTKGHGTKGVVSRYGVKRLPRKTHRGLRKVACIGAWHPARVQFQIPRHGQKGYFHRTERNKKIYRIGLKKDKNNASTDADITEKKITPMGGFPHYGVVNEDFILLKGCVAGTKKRPITLRKTLLPQVSREALSQVALKFIDTSSKIGHGRFQTSEEKTKYYGPLKKDIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H186</accession>
    <name>A0A1J1H186_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha</fullName>
            <ecNumber evidence="4">2.5.1.58</ecNumber>
            <ecNumber evidence="3">2.5.1.59</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">CAAX farnesyltransferase subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">FTase-alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Ras proteins prenyltransferase subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Type I protein geranyl-geranyltransferase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PGAL8A_00463300</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein prenyltransferase subunit alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.58" evidence="4"/>
    <dbReference type="EC" id="2.5.1.59" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529856.1">
        <property type="nucleotide sequence ID" value="XM_028673400.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H186"/>
    <dbReference type="GeneID" id="39733166"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00463300"/>
    <dbReference type="OMA" id="AENCHHC"/>
    <dbReference type="OrthoDB" id="272289at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005953">
        <property type="term" value="C:CAAX-protein geranylgeranyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005965">
        <property type="term" value="C:protein farnesyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004662">
        <property type="term" value="F:CAAX-protein geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004660">
        <property type="term" value="F:protein farnesyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.120">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002088">
        <property type="entry name" value="Prenyl_trans_a"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129">
        <property type="entry name" value="PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129:SF1">
        <property type="entry name" value="PROTEIN FARNESYLTRANSFERASE_GERANYLGERANYLTRANSFERASE TYPE-1 SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01239">
        <property type="entry name" value="PPTA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48439">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51147">
        <property type="entry name" value="PFTA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00040965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00042436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00043086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00043219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG97053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="482" mass="59499" checksum="9C6995CC873E50D2" modified="2017-02-15" version="1">MNEKMEKRNLYVYAKKFNLDYPETFDELNFRILNNPLFNLMKKKNFLIDICDLEKEKKKYMLEEEENIKDKDKINILNTYYSENERLLYSLLASLIENKIYSFEGYIVSSFVIKLNSSYYSAWIYRRKCLKKLNINLLNELKFTKFIINDNIKSFQSWFHRRWLVEYIYKLNEKDKKKNEKRKEKRKNNYKDESNSKIHINYDFFDDDYNFISDNESNSLEEDEYDNDFNEGFISNCDEKDFKIKKDNINLYDDLQNIIDNCNFFKNALKPNEIININEFLREEILYNNCDIFIDAKNYNSWAHKTWLVEKFSIFKNKYLCEKYQILLHEINFINYFLKNDIYNNSVWVYRYFIFNKLNYMNNIIKLEKEIVLCLTYSKQFYDNESLFNYFINIVFKYIELYKKEEKQNTNDIFDINIIQRIKNELTNLQTKSKFVLLFLSQLYSYNKCYNEVIKCYRYLEYNDDFNDQVWKYKIEDIEKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1I8</accession>
    <name>A0A1J1H1I8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00475200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529976.1">
        <property type="nucleotide sequence ID" value="XM_028673534.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1I8"/>
    <dbReference type="GeneID" id="39733285"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00475200"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="162" mass="19897" checksum="430DFC0511589848" modified="2017-02-15" version="1">MISINPLRCKVSIVILIFLIYITMHHEYRSYHNEYLRFPFSKYNQRKLMEMQKENYKYTNTNAIFETDNDYNNFKKKLNNILLILKIGTIIANKMPEYFEIKFDKINNCKNIMNQEEQKQCKSFTLMKHYDLCYQNKEWVMEIVEYSLNYIERLINILNKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2Z5</accession>
    <name>A0A1J1H2Z5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">GPI ethanolamine phosphate transferase 3, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">PIGO</name>
        <name evidence="13" type="ORF">PGAL8A_00528700</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530511.1">
        <property type="nucleotide sequence ID" value="XM_028674127.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2Z5"/>
    <dbReference type="GeneID" id="39733820"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00528700"/>
    <dbReference type="OMA" id="KYVWPIS"/>
    <dbReference type="OrthoDB" id="272139at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051377">
        <property type="term" value="F:mannose-ethanolamine phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16023">
        <property type="entry name" value="GPI_EPT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037675">
        <property type="entry name" value="PIG-O_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039524">
        <property type="entry name" value="PIGO/GPI13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23071:SF1">
        <property type="entry name" value="GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23071">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL GLYCAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
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        </location>
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            <begin position="119"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG97710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1270" mass="152701" checksum="5D707CD3118C2EF7" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H360</accession>
    <name>A0A1J1H360_PLAGA</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
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    <gene>
        <name evidence="3" type="ORF">PGAL8A_00535200</name>
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    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
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        <property type="molecule type" value="Genomic_DNA"/>
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    <evidence type="ECO:0000313" key="3">
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            <dbReference type="EMBL" id="CRG97774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
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    <sequence length="258" mass="30453" checksum="2B35178AB7D7E19A" modified="2017-02-15" version="1">MKTIFQFLFLSLFIKNFFCQNKEGEIDKIHQNNFNSSPNIIIAVNKPQTKKISPINENNIYINRKKQNKLENIINNVEELLQNINDNKNKLVENANGRNYGLNMETEIINANDENVLNILLNGKYNLNKEKKNFSAPIIMVFPQPLTNQEIIDYEKYKELIKSLKKTKNLLLKVGYFEKLSDIKSKNKKEATKEIENTIKIIEKSISRRHIIDEILEEIYDEHRNEDKNIKKLKNESEFLKQKINVLNEKIRKLGYII</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">8A</strain>
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    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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        </location>
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    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="731" mass="88744" checksum="4FD0F077A0D73112" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H384</accession>
    <name>A0A1J1H384_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HCNGP-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00023300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
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            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
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            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
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            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_028674225.1"/>
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    <dbReference type="OrthoDB" id="1714508at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        </location>
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            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="391" mass="46844" checksum="07D199FD33582F35" modified="2017-02-15" version="1">MNLVDYEISSEEEFETLSLNDKKYNNINKNERSCNINKETKIDNNNAEVKKCEHKKFTSFQVEINENNNNEKVLEKENIFSHYKKRKIEKDDMIETNNNSSVESLKENFIIDNEKRNIDKKHSNTLCLDELKKNKELLVGKNELKKYKKELGEENIEEKNEKINIDILKQEQIGENMKEKEKHIYNLKDKEIKNNYKNEINENNSKEYKKKKKNIENEVNKNISKKDDDEKEETKDKTKDKTNKNINNLHKEQNNNNNNNKEKNLNEEIFNNKKFFENNDFMNIDIDENNFDEIFFLRENEYSDTLNKKIDDLSQLYEINLTINKNITNSNEYKNPCILEKIMQIFNIDVYSSNYPINIYNPRDFLSVDLFNEKKDQATQSKAKTKWSNIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3R9</accession>
    <name>A0A1J1H3R9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00042300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG97994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530791.1">
        <property type="nucleotide sequence ID" value="XM_028674439.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3R9"/>
    <dbReference type="GeneID" id="39728948"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00042300"/>
    <dbReference type="OMA" id="NIFTHEI"/>
    <dbReference type="OrthoDB" id="10453727at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="298"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="336" mass="40130" checksum="E6D501529D3E7126" modified="2017-02-15" version="1">MALLYNEGCKNSDDDFTKCDVFLCFIKKTKFRTLYCDPTFKSVIKYISDNISNDLSKNIFTHEITEPLYYRDSKITILSNDNKNGIVFLFEAYPHTNSLISNTYLCRIRKINQKLTLCEYIQENYFEKRLSFRSFDVINREDDNNHRFGLKDITNPRHTINKLKYDDIFFSKDSCHFTTEGFDKIHVCRYSICKKNDRGHIFCKDAKFNGNLINIKEHINYEENQKYIYLPNNCIEENGNFHCTPYLCKYEKMNELYPCDKLEISAVKGINPYIESSEMRSTNSRIIPHENDVRPSTIFAISFFPFLIMLVFIWCYIYKKLRRNRRKDRVDRSKEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2012-05-16" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>H7CDX8</accession>
    <name>H7CDX8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Apicoplast ribosomal protein S5, putative</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Small subunit ribosomal protein 5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rps5</name>
        <name evidence="5" type="synonym">RPS5</name>
        <name evidence="5" type="ORF">PGAL8A_API02200</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <geneLocation type="apicoplast" evidence="4"/>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Mol. Biol. Evol." volume="29" first="2095" last="2099">
            <title>The Plasmodium Apicoplast Genome: Conserved Structure and Close Relationship of P. ovale to Rodent Malaria Parasites.</title>
            <authorList>
                <person name="Arisue N."/>
                <person name="Hashimoto T."/>
                <person name="Mitsui H."/>
                <person name="Palacpac N.M.Q."/>
                <person name="Kaneko A."/>
                <person name="Kawai S."/>
                <person name="Hasegawa M."/>
                <person name="Tanabe K."/>
                <person name="Horii T."/>
            </authorList>
            <dbReference type="PubMed" id="22396524"/>
            <dbReference type="DOI" id="10.1093/molbev/mss082"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">A8</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">8A</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AB649424">
        <property type="protein sequence ID" value="BAL70748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LN835293">
        <property type="protein sequence ID" value="CRG98237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009325464.1">
        <property type="nucleotide sequence ID" value="NC_031963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="H7CDX8"/>
    <dbReference type="GeneID" id="30315801"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_API02200"/>
    <dbReference type="OMA" id="NIYYFKY"/>
    <dbReference type="OrthoDB" id="309483at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Apicoplast API"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_uS5_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0933">Apicoplast</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="S5 DRBM" evidence="3">
        <location>
            <begin position="96"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAL70748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG98237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="237" mass="29102" checksum="78C1DDF12091BE42" modified="2012-05-16" version="1">MNINNIKLNNFYILYYVLILLRSLFILFSNKFKYDVKYIYKIYYIIILYLKLYYIINKLYNNNIIYYNNYNYIYFYIYKYNNIVIKNNYKIIYNNIIEKIIEIKKVSYTIKKGRIKRYKVLLLIGNKRGWIGIGIGKSYNINKAILLAKINGLNNIYYFKYSLLNVYKLKCIYFNSNKLFIKLKFNIYNDLNIKFLLFKYLFECLGYLNCKVIIYYNIINNKYNLLNKLLLVLFNNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2012-07-11" modified="2026-01-28" version="52" xmlns="https://uniprot.org/uniprot">
    <accession>I2FKC4</accession>
    <name>I2FKC4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 15">Pyruvate kinase</fullName>
            <ecNumber evidence="5 15">2.7.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">PK</name>
        <name evidence="19" type="ORF">PGAL8A_00155300</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2012" name="Gene" volume="502" first="36" last="39">
            <title>Age of the last common ancestor of extant Plasmodium parasite lineages.</title>
            <authorList>
                <person name="Hayakawa T."/>
                <person name="Tachibana S."/>
                <person name="Hikosaka K."/>
                <person name="Arisue N."/>
                <person name="Matsui A."/>
                <person name="Horii T."/>
                <person name="Tanabe K."/>
            </authorList>
            <dbReference type="PubMed" id="22555021"/>
            <dbReference type="DOI" id="10.1016/j.gene.2012.04.037"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="19 20" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>pyruvate + ATP = phosphoenolpyruvate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18157"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.40"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 15">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 15">Belongs to the pyruvate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.40" evidence="5 15"/>
    <dbReference type="EMBL" id="AB571133">
        <property type="protein sequence ID" value="BAM15609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="I2FKC4"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00155300"/>
    <dbReference type="OMA" id="HQGRYDR"/>
    <dbReference type="OrthoDB" id="108365at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00188"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004743">
        <property type="term" value="F:pyruvate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.33.10:FF:000001">
        <property type="entry name" value="Pyruvate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.60:FF:000001">
        <property type="entry name" value="Pyruvate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.33.10">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.20">
        <property type="entry name" value="Pyruvate kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001697">
        <property type="entry name" value="Pyr_Knase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018209">
        <property type="entry name" value="Pyrv_Knase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015793">
        <property type="entry name" value="Pyrv_Knase_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015795">
        <property type="entry name" value="Pyrv_Knase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036918">
        <property type="entry name" value="Pyrv_Knase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015806">
        <property type="entry name" value="Pyrv_Knase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004491">
        <property type="entry name" value="PRK05826.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004978">
        <property type="entry name" value="PRK06354.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01064">
        <property type="entry name" value="pyruv_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11817">
        <property type="entry name" value="PYRUVATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00224">
        <property type="entry name" value="PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02887">
        <property type="entry name" value="PK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01050">
        <property type="entry name" value="PYRUVTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52935">
        <property type="entry name" value="PK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00110">
        <property type="entry name" value="PYRUVATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12 15" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="9 15 18" id="KW-0418">Kinase</keyword>
    <keyword evidence="11 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13 18" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate kinase barrel" evidence="16">
        <location>
            <begin position="37"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate kinase C-terminal" evidence="17">
        <location>
            <begin position="395"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="BAM15609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="CRG93844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="511" mass="55872" checksum="A7C41AA8888A4000" modified="2012-07-11" version="1">MNSFKFKHSSSNANLQSAAHITLRQILEPSNVDLRSKKTHIVCTLGPSCKSVETLVELIDAGMDICRFNFSHGTHEDHKEMFNNVLKAQQLRPNCLLGMLLDTKGPEIRTGLLKNKEVHLKEGSKLKLVTDYDFLGDETCIACSYKKLPQSVKKGNIILIADGSVSCKVLETHDDHVITEVLNSATIGEKKNMNLPNVKVDLPIISEKDKNDILNFAIPMGCNFIAASFIQSAEDVRLIRNLLGPRGRHIKIIPKIENIEGIVHFDKILAESDGIMIARGDLGMEISPEKVFLAQKLMISKCNLQGKPIITATQMLESMTKNPRPTRAEVTDVANAVLDGTDCVMLSGETASGKFPIQAVTIMSKICIEAEACIDYKLLYQSIVNAIDTPISVQEAVARSAVETAESIDATLIIALTETGYTARLIAKYKPSCRILALSASESTVRCLSIHRGITCIKVGSFQGTDVVLRNALEIAKERNLVKVGDSVIAIHGIKEEVAGGTNLMKVVQIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKR0</accession>
    <name>A0A1J1GKR0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Secreted ookinete protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">PSOP13</name>
        <name evidence="4" type="ORF">PGAL8A_00066200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG92958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525780.1">
        <property type="nucleotide sequence ID" value="XM_028673309.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKR0"/>
    <dbReference type="GeneID" id="39729187"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00066200"/>
    <dbReference type="OMA" id="LMFLMSE"/>
    <dbReference type="OrthoDB" id="366009at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012881983" evidence="3">
        <location>
            <begin position="21"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="85"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG92958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="201" mass="23236" checksum="082283515568265E" modified="2017-02-15" version="1">MNKLFFFFFFVNLFLSKSLCEKTEILPLGDILSGVADIANVVSGKNENVTNVVSESTPKINLKIVPSKKLHITKNDMMFLLSELRQEIGRQISILEDELEEKERMKQRSASLWATSHSPVYVPQENNQTEEINNINDEDKEEIEDLLDSLNKISNDENIKEKGNLTYNIEIRDKKNFDEKETSDNVMHFRQKTLRNGPITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLL4</accession>
    <name>A0A1J1GLL4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transporter, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00100800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC43A transporter (TC 2.A.1.44) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526124.1">
        <property type="nucleotide sequence ID" value="XM_028672732.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLL4"/>
    <dbReference type="GeneID" id="39729532"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00100800"/>
    <dbReference type="OrthoDB" id="330047at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052599">
        <property type="entry name" value="SLC43A_AATransporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20772">
        <property type="entry name" value="PROTEIN FMP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20772:SF2">
        <property type="entry name" value="PROTEIN FMP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="149"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="211"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="415"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="455"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="479"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="503"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="539"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="573"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="599" mass="69644" checksum="41FAD639B6A839A5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM54</accession>
    <name>A0A1J1GM54_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Protein kinase 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PK1</name>
        <name evidence="10" type="ORF">PGAL8A_00114200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526258.1">
        <property type="nucleotide sequence ID" value="XM_028674221.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM54"/>
    <dbReference type="GeneID" id="39729667"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00114200"/>
    <dbReference type="OrthoDB" id="63265at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050591">
        <property type="entry name" value="GSK-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24057">
        <property type="entry name" value="GLYCOGEN SYNTHASE KINASE-3 ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24057:SF0">
        <property type="entry name" value="PROTEIN KINASE SHAGGY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="35"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="174"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG93436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="939" mass="109933" checksum="F45544F04B31D2FA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM57</accession>
    <name>A0A1J1GM57_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA helicase, putative</fullName>
            <ecNumber evidence="6">3.6.4.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00111700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526233.1">
        <property type="nucleotide sequence ID" value="XM_028673943.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM57"/>
    <dbReference type="GeneID" id="39729642"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00111700"/>
    <dbReference type="OMA" id="CCKAKLH"/>
    <dbReference type="OrthoDB" id="448448at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17919">
        <property type="entry name" value="DEXHc_Snf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10799">
        <property type="entry name" value="SNF2/RAD54 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="1 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="4">
        <location>
            <begin position="188"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="5">
        <location>
            <begin position="777"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="31"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="750"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="507"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="31"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="938" mass="110930" checksum="5D98FE03305A2197" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM63</accession>
    <name>A0A1J1GM63_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Transcription factor with AP2 domain(S), putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ApiAP2</name>
        <name evidence="12" type="ORF">PGAL8A_00123500</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial solute-binding protein 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526350.1">
        <property type="nucleotide sequence ID" value="XM_028674750.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729760"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00123500"/>
    <dbReference type="OrthoDB" id="387376at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028078">
        <property type="entry name" value="ACDC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006061">
        <property type="entry name" value="SBP_1_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14733">
        <property type="entry name" value="ACDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00847">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01037">
        <property type="entry name" value="SBP_BACTERIAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AP2/ERF" evidence="10">
        <location>
            <begin position="1760"/>
            <end position="1811"/>
        </location>
    </feature>
    <feature type="domain" description="AP2-coincident C-terminal" evidence="11">
        <location>
            <begin position="2386"/>
            <end position="2476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="239"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1344"/>
            <end position="1453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1868"/>
            <end position="1892"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="2479"/>
            <end position="2509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="242"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="1870"/>
            <end position="1882"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG93528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2509" mass="294787" checksum="F3EAB2F5458769E8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMB1</accession>
    <name>A0A1J1GMB1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00127300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526388.1">
        <property type="nucleotide sequence ID" value="XM_028674793.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMB1"/>
    <dbReference type="GeneID" id="39729798"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00127300"/>
    <dbReference type="OMA" id="QNVYFLC"/>
    <dbReference type="OrthoDB" id="377714at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="289"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="464" mass="56582" checksum="99F8C6615CF5F980" modified="2017-02-15" version="1">MNEKIKWNNKRTCKIYGNKLKDLEQHKKDFTLFYITDLLNIIYNTYKSIKPVYIHFICSKKNENLHPKKNNLIYYTPNSILEQYFPEYFQNVYFLCAHYTIWENKINENRNDTYQNYANKKEHNEHKLNNLNENDTSQNNENKETFYFIFTFYMEPNFIWEEINIPIFHERGYIECKFDSIDNLMKINSFVNLSDNLRIYTYNKTLIQYIFDLSNNNNITCDNSNINKNKEDCNNFKNVHLLPFFISTDYLHKNCKICKTRVISFNEKDIYCKIDEEENLPKSILLFMRKKLNTKLKSIEKEAAKEEREREREREVKMFNNQNSIKKKVKNYDDDYFIGLNYTKVKQIINLTDDTFKNYFSDQELENVLLMMNKNNYSKNKENAYVINDNIINMYFELDEYYNFINRNKNQFKNTLSDPWQLGIDHNIGNDKNIFEKKKKFLINDFKIHKRFNKKIKKKKKRAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMD8</accession>
    <name>A0A1J1GMD8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Heat shock 70 kDa protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Cytoplasmic antigen</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00111900</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526235.1">
        <property type="nucleotide sequence ID" value="XM_028673965.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMD8"/>
    <dbReference type="GeneID" id="39729644"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00111900"/>
    <dbReference type="OMA" id="VCKPIVT"/>
    <dbReference type="OrthoDB" id="413580at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10233">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.34.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000002">
        <property type="entry name" value="Heat shock 70 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000172">
        <property type="entry name" value="Heat shock 70 kDa protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000001">
        <property type="entry name" value="heat shock 70 kDa protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.10:FF:000022">
        <property type="entry name" value="Heat shock protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000026">
        <property type="entry name" value="Heat shock protein 70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001413">
        <property type="entry name" value="PRK00290.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="651"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="265"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="658"/>
            <end position="672"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00078634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG93413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="672" mass="73499" checksum="3CAC01C1BB34C399" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMM8</accession>
    <name>A0A1J1GMM8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00141000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526526.1">
        <property type="nucleotide sequence ID" value="XM_028674946.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMM8"/>
    <dbReference type="GeneID" id="39729934"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00141000"/>
    <dbReference type="OMA" id="MMKDASH"/>
    <dbReference type="OrthoDB" id="381694at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="18"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="120" mass="14108" checksum="880F1204952AB05C" modified="2017-02-15" version="1">MRKKDSEYIINSTYESCLRKLEENMQKSKLALKNEKEKKINIKDIEFNIKNHMNEMTKLVKEAKIINSSTSNNIKDFYNGLMKCEELCNQLTSDEINQKINETFNNIVTEINNKCKPIVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMP9</accession>
    <name>A0A1J1GMP9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">RNA-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00131600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SF-assemblin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526433.1">
        <property type="nucleotide sequence ID" value="XM_028674842.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMP9"/>
    <dbReference type="GeneID" id="39729841"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00131600"/>
    <dbReference type="OMA" id="NCNMCNI"/>
    <dbReference type="OrthoDB" id="372799at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008374">
        <property type="entry name" value="SF_assemblin/giardin_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40412">
        <property type="entry name" value="SF-ASSEMBLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40412:SF1">
        <property type="entry name" value="SF-ASSEMBLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="261"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="394" mass="46992" checksum="BAF7AB3E1F32718D" modified="2017-02-15" version="1">MDSDKKYNFQGNYNGNSYDKNMNYYNNVNNCYYNYDEDKRNLKISKNNNNNMHYNEEESYNSNFLYNYNMNNANYNQANYNNYCNYNLNYSGFNNYSNNLTNYSQNYYSNDQYILNKKAAKILYIYNMSNEYTDENFIYSLCFIYGNIDSVCYIKGKNLFIVKFVSADCALNAYNNLPKYFKNLQFELRNESKKISYFNEKVNSNKYVSPNISEKKFLSLSAEKREQIMNIKQKELLRKCKEKLNEYINMFNNKNITNETKRELQTLIDHLKKRIQLLNNQCDNSNFNELSNSIILNNYNNNNDNNNIENSTTLKISSLNNIRNNEELSNYILKNNSVFLNEHISYFSLFSFGEKYAIIKYNNENIAKNVFQNCQIYNIQVEFVPDDTANKNEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMW8</accession>
    <name>A0A1J1GMW8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mitochondrial cardiolipin synthase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00138000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526497.1">
        <property type="nucleotide sequence ID" value="XM_028674914.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMW8"/>
    <dbReference type="GeneID" id="39729905"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00138000"/>
    <dbReference type="OMA" id="WLNFEVT"/>
    <dbReference type="OrthoDB" id="14911at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030572">
        <property type="term" value="F:phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032049">
        <property type="term" value="P:cardiolipin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd09110">
        <property type="entry name" value="PLDc_CLS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21248">
        <property type="entry name" value="CARDIOLIPIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21248:SF22">
        <property type="entry name" value="PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="1">
        <location>
            <begin position="171"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="1">
        <location>
            <begin position="408"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="533" mass="62774" checksum="26F3EEB8B5E4A033" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN80</accession>
    <name>A0A1J1GN80_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Oxidoreductase, short-chain dehydrogenase family, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00154600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526658.1">
        <property type="nucleotide sequence ID" value="XM_028675092.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN80"/>
    <dbReference type="GeneID" id="39730070"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00154600"/>
    <dbReference type="OMA" id="APHIRRY"/>
    <dbReference type="OrthoDB" id="1274115at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157:SF31">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43157">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="389" mass="45590" checksum="BE46F0E0358A1833" modified="2017-02-15" version="1">MEVRNKSKSFLGVIFTDPSLKRSIIFIFISGIIWFLPFYKALLYLVFKNYSNISSVYNKFYEYITNIIIIITYYYILRKKNIGGTIKDVLINKNKLKGKRILVTGGYKGIGLAAVKEFLKFGCEIILACRSLKYMELVRTDLMTTFPDAKIHCVELDLGSYESIENCAKYILKNFSKIDIIVNNAGFLNQKIEYINKLESVFFINYFGHFYLTKLMYELILSSDTLIVNLSSIAHCMLKESDINYDFIYEKNTKNIKVSFLYRKEYAFSKLCMLYFTQQLQKRLENEETKACSVSINPGLVKTDIFRNEHFCFRPLCTDIFFNKTPLQGAQSILYVCLLDREELAKGCYYSDCKVDYIRTYANNQKKSEELWEISEEILKNKTKYYSNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN91</accession>
    <name>A0A1J1GN91_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein root UVB sensitive/RUS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00151200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526625.1">
        <property type="nucleotide sequence ID" value="XM_028675055.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN91"/>
    <dbReference type="GeneID" id="39730036"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00151200"/>
    <dbReference type="OMA" id="MTYASIR"/>
    <dbReference type="OrthoDB" id="372159at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054549">
        <property type="entry name" value="UVB_sens_RUS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35711:SF1">
        <property type="entry name" value="ECTODERMAL, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35711">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04884">
        <property type="entry name" value="UVB_sens_prot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="388"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="423"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="Protein root UVB sensitive/RUS" evidence="3">
        <location>
            <begin position="80"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="446" mass="53056" checksum="4F921524FCF32F6F" modified="2017-02-15" version="1">MKILLFLLFISLCYISFSFSFLIKANIKLLKLTSINYVTLDKKGKNLINNHVHRKNIRSLKSFLYPHFLKRIIEPLENANFKNYFFFRSLSRICVSLSSAFSLNAKLNLYRKNTNNLLLTQLLMNNEILIKILKICWLYKLSHFIDKNIKLCRYMSTIFYIISIYLDILSTYNISKNFYFYYFLYSLSSILKNLSILTYTSIRSSINFHVSQMLSNSNQKFNEKSIRDIKLVNKDTYDKNISNENINDENKDKNKNDENVDKNKNDENVDKNKNDENEDKNINDENKDKNINEENVDKNINDENEDKNINDENKDKNINEENVDKNINDENKDKNINDENEDKNIDEKLMEVNTLKKEYNILKKVYEKKKENNNSNILRNNLKVKRKFYIGEISVITDLLFSLVDLSTILLLSHAAKFIKQKIFFYIFLSSLHLFFSYKELEYLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNA5</accession>
    <name>A0A1J1GNA5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00153700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526649.1">
        <property type="nucleotide sequence ID" value="XM_028675082.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNA5"/>
    <dbReference type="GeneID" id="39730061"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00153700"/>
    <dbReference type="OMA" id="PSCIGCS"/>
    <dbReference type="OrthoDB" id="387008at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="249"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="308"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="369" mass="43502" checksum="E1A110773A9A2D6E" modified="2017-02-15" version="1">MESTNANFSFDMLDMIDNCDSVKPEDKSEGKNDTKENIIEININKKKTEVFHNNTTIIDGIKKSRRKKNKTNFKIFPEVSDAKHEVIYESKENHNNNLIKTKVNSNENKFKRRQKKNKIVEKVLNRKILKNSNLNIFSNEEKLNNEIINQNVSNENSLNTHFYKNITSNCKIQNNKDDLGTYEFENCKNNNNNNNNNNNNNNNASLNEIDKVDKDIFSKSYECDNCKNYLKELSCKNYMNFSIYGEYINDGENNMLLLKNKKIEELENKNKLMLNKIESLRRKNSFLSDKIKKFSTSLTDINLNFNKLIKENNLLKEINTNLSEALEKEKSYNLQRQKENTCKELTYCDKSVEEEFEDSIDKEIFNEHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNG1</accession>
    <name>A0A1J1GNG1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mitochondrial ribosomal protein S17, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00171600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526830.1">
        <property type="nucleotide sequence ID" value="XM_028670038.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNG1"/>
    <dbReference type="GeneID" id="39730243"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00171600"/>
    <dbReference type="OMA" id="RIGPWKT"/>
    <dbReference type="OrthoDB" id="274752at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00364">
        <property type="entry name" value="Ribosomal_uS17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000242">
        <property type="entry name" value="Mitochondrial ribosomal protein S17,putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000266">
        <property type="entry name" value="Ribosomal_uS17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S11 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US17M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00366">
        <property type="entry name" value="Ribosomal_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="115" mass="13899" checksum="3398DC5B4447343B" modified="2017-02-15" version="1">MIKLNIIHSYWHYKAWQRATAGYLRTFIKNNLANNEMIGYVINDKHPKSIRVACDRYMYVVRYKKTFRYTKKIWAHDEKSEAKVGDVVRIQPLGYRIGPWKNYILVKILYKENKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNH6</accession>
    <name>A0A1J1GNH6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Zinc finger protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00165000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ZPR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526762.1">
        <property type="nucleotide sequence ID" value="XM_028675207.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNH6"/>
    <dbReference type="GeneID" id="39730175"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00165000"/>
    <dbReference type="OMA" id="FREVVIM"/>
    <dbReference type="OrthoDB" id="308464at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1040">
        <property type="entry name" value="ZPR1, A/B domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.420">
        <property type="entry name" value="ZPR1, zinc finger domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004457">
        <property type="entry name" value="Znf_ZPR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040141">
        <property type="entry name" value="ZPR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042451">
        <property type="entry name" value="ZPR1_A/B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056180">
        <property type="entry name" value="ZPR1_jr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042452">
        <property type="entry name" value="ZPR1_Znf1/2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00310">
        <property type="entry name" value="ZPR1_znf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10876">
        <property type="entry name" value="ZINC FINGER PROTEIN ZPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10876:SF0">
        <property type="entry name" value="ZINC FINGER PROTEIN ZPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22794">
        <property type="entry name" value="jr-ZPR1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03367">
        <property type="entry name" value="Zn_ribbon_ZPR1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00709">
        <property type="entry name" value="Zpr1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Zinc finger ZPR1-type" evidence="6">
        <location>
            <begin position="28"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="Zinc finger ZPR1-type" evidence="6">
        <location>
            <begin position="351"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="154"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="156"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="196"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="563" mass="65194" checksum="8E79004B4BB770F6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNK0</accession>
    <name>A0A1J1GNK0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribosome biogenesis protein MRT4, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00174100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526855.1">
        <property type="nucleotide sequence ID" value="XM_028670065.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNK0"/>
    <dbReference type="GeneID" id="39730268"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00174100"/>
    <dbReference type="OMA" id="KYMWDVQ"/>
    <dbReference type="OrthoDB" id="10262308at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.105.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_uL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040637">
        <property type="entry name" value="Ribosomal_uL10-like_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043164">
        <property type="entry name" value="Ribosomal_uL10-like_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_uL10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051742">
        <property type="entry name" value="Ribosome_Assembly_uL10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45841:SF1">
        <property type="entry name" value="MRNA TURNOVER PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45841">
        <property type="entry name" value="MRNA TURNOVER PROTEIN 4 MRTO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17777">
        <property type="entry name" value="RL10P_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="Ribosomal protein L10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL10-like insertion" evidence="2">
        <location>
            <begin position="132"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="223" mass="26174" checksum="E1538B6E92998ED8" modified="2017-02-15" version="1">MPKSKRNVTISLTKVKKKLNKKEKKDLKLTELKKFIEIPNIYIYVLDIRTYSNNNLKKVIEHFKPNGKFFFGKNKLMRLALGTNQENEVKPNIYKISELLVGNKMLLITKDTPLKVIKFFNEFQPEEYITHGNISPQNVTLKQGEVLNVPVSMQKDLQKRKLNFDIIDQKIILRENKVLAEKDKIINIENAKILRMLNMKIAKFDISVLGYWHPNNFVSLMQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNM9</accession>
    <name>A0A1J1GNM9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fam-h protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00177000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526879.1">
        <property type="nucleotide sequence ID" value="XM_028670093.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNM9"/>
    <dbReference type="GeneID" id="39730297"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00177000"/>
    <dbReference type="OMA" id="NTYETWN"/>
    <dbReference type="OrthoDB" id="10561801at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="93"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="232" mass="27121" checksum="5BB4FF5B6D03340B" modified="2017-02-15" version="1">MNKKNNIFLIPNINKYTGYYSHLDKNFITAYMSTSNINMKKEKRNILNFLINFFIFILLIWILQCFNNCDSCSLWNNKRDLKSVINVDIKRSLAESKNTTEQISEELKCYKEKDTIEIDLNSRNDQREMEENIEVELKNELETMKDNEKVKTSEGILQFCKGCLKIVSLSIAFILSFCSSVLITAESPHFGPKTPYDRSNIHSLTILTNLSLMIISIILIHERVVIKYKKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNU1</accession>
    <name>A0A1J1GNU1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00166600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526779.1">
        <property type="nucleotide sequence ID" value="XM_028669982.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNU1"/>
    <dbReference type="GeneID" id="39730192"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00166600"/>
    <dbReference type="OMA" id="WPEGDYR"/>
    <dbReference type="OrthoDB" id="1749473at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12383">
        <property type="entry name" value="RRM_RBM42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050825">
        <property type="entry name" value="RBM42_RBP45_47-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034215">
        <property type="entry name" value="RBM42_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47640:SF11">
        <property type="entry name" value="RNA-BINDING PROTEIN 42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47640">
        <property type="entry name" value="TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="49"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="162"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="180" mass="21034" checksum="158895AA399174BC" modified="2017-02-15" version="1">MKTNEQMTKQMDVSPSKDDKSNKKKVHLRKAAGIVWKDPTLDEWPENDFRIFCGNLGNEVSNDILANAFRKYKSFNMAKVIRDKRNNKTKGYGFVSLSDPQDMLDALKTMNNKFIGNRPITVKRSKWKDREIDSKKNKDFDNFLKDAHLPAKKYRKFKKHVKNDNSKDVHDKLINKNAVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPB3</accession>
    <name>A0A1J1GPB3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00403900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527156.1">
        <property type="nucleotide sequence ID" value="XM_028670400.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPB3"/>
    <dbReference type="GeneID" id="39732569"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00403900"/>
    <dbReference type="OMA" id="QDFKQQC"/>
    <dbReference type="OrthoDB" id="346528at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="126" mass="15240" checksum="ECF37F065B80FCB4" modified="2017-02-15" version="1">MNAFKNNFKKFSYLNQKRFLGNTVRGPLPKEISKNVEYAFDFFTKRAHTYQDFKQQCESLRIFIYFGLVTFLSIDFLINPLKSTYWEKFMPINLFKCFFNSFLNKQDNIFRHNGCSSYEKYIQLIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPE7</accession>
    <name>A0A1J1GPE7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Rhoptry associated adhesin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00388400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527001.1">
        <property type="nucleotide sequence ID" value="XM_028670228.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPE7"/>
    <dbReference type="GeneID" id="39732414"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00388400"/>
    <dbReference type="OMA" id="ECQNIFF"/>
    <dbReference type="OrthoDB" id="392803at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012249865" description="Rhoptry associated adhesin" evidence="2">
        <location>
            <begin position="23"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="295" mass="34347" checksum="3EC86AE4406D4BDC" modified="2017-02-15" version="1">MKKLFVFLIICIFKIWIEKVKASKFISFKRKKNVTSLDINHLNNKENGSYSFLMTKKENDEEKDNKDGNSKKEKENDENGSNDKKNEENSSNEKRHEEDNVSEKKNKENSTERKHEEDNTNEKKHEDDNSTEKKHEEGNPSEKKNEEDNSNEKKNEEENSSEKNNDESNIKKKDENTPVEKNITKSNLLEYGTHDRDGNFIPSYKTLTDEILSTNNSLEKSLSFLKIACSHILKILEFIPESKLSSQYIKIESKNVYLKDIGSECQSLYFSLQKLGMTVIVLNSKISKLIYVQEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPL7</accession>
    <name>A0A1J1GPL7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Nucleolar rRNA processing protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00184100</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527270.1">
        <property type="nucleotide sequence ID" value="XM_028670526.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPL7"/>
    <dbReference type="GeneID" id="39730368"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00184100"/>
    <dbReference type="OMA" id="TEKTWRM"/>
    <dbReference type="OrthoDB" id="10251154at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000378">
        <property type="entry name" value="U3 small nucleolar RNA-associated protein 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012952">
        <property type="entry name" value="BING4_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040315">
        <property type="entry name" value="WDR46/Utp7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14085:SF3">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 46"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14085">
        <property type="entry name" value="WD-REPEAT PROTEIN BING4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08149">
        <property type="entry name" value="BING4CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01033">
        <property type="entry name" value="BING4CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="384"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="BING4 C-terminal" evidence="8">
        <location>
            <begin position="461"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="122"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="581"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="122"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="586"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="616"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="640"/>
            <end position="652"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="652" mass="76062" checksum="0708EA147A53847D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPW5</accession>
    <name>A0A1J1GPW5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein SIS1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SIS1</name>
        <name evidence="3" type="ORF">PGAL8A_00403800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527155.1">
        <property type="nucleotide sequence ID" value="XM_028670398.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPW5"/>
    <dbReference type="GeneID" id="39732568"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00403800"/>
    <dbReference type="OMA" id="RVCPTCV"/>
    <dbReference type="OrthoDB" id="550424at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000006">
        <property type="entry name" value="DnaJ subfamily B member 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000047">
        <property type="entry name" value="Heat shock 40 kDa protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000015">
        <property type="entry name" value="Heat shock protein 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051339">
        <property type="entry name" value="DnaJ_subfamily_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24078:SF553">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24078">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="4"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="328" mass="37309" checksum="400423EC07717B32" modified="2017-02-15" version="1">MGKDYYSILGVSKDATTNDLKKAYRKMAMMWHPDKHKDVKSKKEAEEKFKNIAEAYDVLSDEEKRKIYDTYGEEGLKGSIPTGGNTYVYSGVDPSELFSRIFGSDSQFSFTSAFDEDFSPFSTFVNMTSRKTRPSTTTNINSNNYNKPATYEVPLSLTLEELYSGCKKKLKITRKRFMGTKSYEDDNFVTIDVKAGWKDGTKITFYGEGDQLSPMAQPGDLVFKVKTKAHDRFLRDSNHLIYKCPVPLDKALTGFQFIVKSLDNRDINVRIDDIVTPKTRKIVANEGMPSSKHPGMKGDLIVEFDIVFPKNLTSEKKRIIREVLANTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ12</accession>
    <name>A0A1J1GQ12_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00108000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526197.1">
        <property type="nucleotide sequence ID" value="XM_028673544.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ12"/>
    <dbReference type="GeneID" id="39729606"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00108000"/>
    <dbReference type="OrthoDB" id="371103at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="33"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1008" mass="119839" checksum="AABFA69555DAA987" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ44</accession>
    <name>A0A1J1GQ44_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BRIX domain, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00112100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526237.1">
        <property type="nucleotide sequence ID" value="XM_028673988.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ44"/>
    <dbReference type="GeneID" id="39729646"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00112100"/>
    <dbReference type="OrthoDB" id="10261452at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007109">
        <property type="entry name" value="Brix"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04427">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00879">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50833">
        <property type="entry name" value="BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Brix" evidence="2">
        <location>
            <begin position="40"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="287" mass="34016" checksum="10928793665B337C" modified="2017-02-15" version="1">MVTKKENKVKKEIKINNKYKNDGKHKQEEKESDEKIIKKTNIMVIKKKGMNSELKTLCRELVDLFIPYCALFYIKKLKNLSELNKKLKELSYKYTICIYIQNFKLLYSITSNYTKLSLTFIIQSFTTSSLVKSKYSKNANHNYNNLKPLLILKNFNNNANSDMLNYLIIIQNVLKNLYPCVNLKSDFSHKPRRVVLYCYNNNDETIYFRQYVTNLKKRSFKKILNEAYKKDLSGYDDVFNYISSKIDINNFSNEKEIEMIEIGPRVSYKLFKITDQDKVIYSLGDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQD8</accession>
    <name>A0A1J1GQD8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00211600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527534.1">
        <property type="nucleotide sequence ID" value="XM_028670819.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQD8"/>
    <dbReference type="GeneID" id="39730643"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00211600"/>
    <dbReference type="OMA" id="DDDLHCG"/>
    <dbReference type="OrthoDB" id="386594at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="539"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="633"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="729"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="184"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="636"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="729"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="752"/>
            <end position="764"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="772" mass="92626" checksum="19241615D1438A24" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQH1</accession>
    <name>A0A1J1GQH1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Asparagine-rich protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">AARP</name>
        <name evidence="2" type="ORF">PGAL8A_00193600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000029">
        <property type="protein sequence ID" value="CRG94538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527353.1">
        <property type="nucleotide sequence ID" value="XM_028670618.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQH1"/>
    <dbReference type="GeneID" id="39730461"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00193600"/>
    <dbReference type="OMA" id="HDNADHV"/>
    <dbReference type="OrthoDB" id="10646864at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="192" mass="21567" checksum="D7AD39F51B756226" modified="2017-02-15" version="1">MNANNIISILIVFIYYINSQQILRKRKFHNNSYLLNTEDKKLKNINNLKNIDSPNQIEFEYNATNSKNDNIFSLEKENKGSFILLSSKLKEKESDDDDDDGDEDDEDDDDDDDGEKEKEKENEENEKGNGKGDEKESRSNNNSNSVPYTALPPPPPPVPPPPHPIPPMTPSSIVGNVVSNVVTTGLKLIGIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQQ6</accession>
    <name>A0A1J1GQQ6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00224400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527662.1">
        <property type="nucleotide sequence ID" value="XM_028670961.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQQ6"/>
    <dbReference type="GeneID" id="39730771"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00224400"/>
    <dbReference type="OMA" id="ERCKECR"/>
    <dbReference type="OrthoDB" id="444121at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="275" mass="32288" checksum="9F13D63A34969DCF" modified="2017-02-15" version="1">MLSKSGRNVLLKCLKSDRNSAFSNLINIYEVCGNEILRKYSTGIHNLSTNIINQNSYSFLNKNNQILKINLRKCFSTSSIQSNITSGQTTKNVSSECSKNLSIVDNSNVLIFFDKNQPETIGQKIYRYLDITGFLTRYNNRKEWILDLDPYTRLSTVMLTEYERKLMIFLKFHVYLLFGACVYLWYHAQIHFTMKPPCPKPYAYGHLDGRKRDFTWHGKLFFIYPKTRCKECRWLDVQCKKECFEKLKLEGHKFIINKGDPLSVPKTVLYPSHFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQS7</accession>
    <name>A0A1J1GQS7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cysteine proteinase falcipain 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">FP1</name>
        <name evidence="13" type="ORF">PGAL8A_00217300</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527591.1">
        <property type="nucleotide sequence ID" value="XM_028670883.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQS7"/>
    <dbReference type="GeneID" id="39730700"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00217300"/>
    <dbReference type="OMA" id="FCLSYRC"/>
    <dbReference type="OrthoDB" id="190265at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02248">
        <property type="entry name" value="Peptidase_C1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025661">
        <property type="entry name" value="Pept_asp_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000169">
        <property type="entry name" value="Pept_cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025660">
        <property type="entry name" value="Pept_his_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013128">
        <property type="entry name" value="Peptidase_C1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000668">
        <property type="entry name" value="Peptidase_C1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039417">
        <property type="entry name" value="Peptidase_C1A_papain-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013201">
        <property type="entry name" value="Prot_inhib_I29"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12411">
        <property type="entry name" value="CYSTEINE PROTEASE FAMILY C1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08246">
        <property type="entry name" value="Inhibitor_I29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00112">
        <property type="entry name" value="Peptidase_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00705">
        <property type="entry name" value="PAPAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00848">
        <property type="entry name" value="Inhibitor_I29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00645">
        <property type="entry name" value="Pept_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00640">
        <property type="entry name" value="THIOL_PROTEASE_ASN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00139">
        <property type="entry name" value="THIOL_PROTEASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00639">
        <property type="entry name" value="THIOL_PROTEASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0865">Zymogen</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="Cathepsin propeptide inhibitor" evidence="12">
        <location>
            <begin position="194"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C1A papain C-terminal" evidence="11">
        <location>
            <begin position="295"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG94776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="524" mass="61790" checksum="F0EDD21625372633" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR96</accession>
    <name>A0A1J1GR96_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Translation initiation factor EIF-2B subunit related</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00234300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527759.1">
        <property type="nucleotide sequence ID" value="XM_028671069.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR96"/>
    <dbReference type="GeneID" id="39730870"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00234300"/>
    <dbReference type="OrthoDB" id="361369at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="2">
        <location>
            <begin position="1226"/>
            <end position="1256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="361"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="874"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="874"/>
            <end position="894"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1258" mass="151798" checksum="B8023EC3EF03C07B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRC8</accession>
    <name>A0A1J1GRC8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Chaperone binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00246400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AHA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527878.1">
        <property type="nucleotide sequence ID" value="XM_028671203.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRC8"/>
    <dbReference type="GeneID" id="39730992"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00246400"/>
    <dbReference type="OrthoDB" id="298012at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001671">
        <property type="term" value="F:ATPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.15.10.20">
        <property type="entry name" value="Activator of Hsp90 ATPase Aha1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036338">
        <property type="entry name" value="Aha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015310">
        <property type="entry name" value="AHSA1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039663">
        <property type="entry name" value="AIP/AIPL1/TTC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11242">
        <property type="entry name" value="ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11242:SF0">
        <property type="entry name" value="TPR_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09229">
        <property type="entry name" value="Aha1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01000">
        <property type="entry name" value="Aha1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103111">
        <property type="entry name" value="Activator of Hsp90 ATPase, Aha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 4" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="4">
        <location>
            <begin position="89"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Activator of Hsp90 ATPase AHSA1-like N-terminal" evidence="6">
        <location>
            <begin position="349"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="238"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="238"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="266"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="513" mass="61289" checksum="72BE2A6B9D5577B4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRE0</accession>
    <name>A0A1J1GRE0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ER lumen protein retaining receptor 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00242700</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ERD2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527842.1">
        <property type="nucleotide sequence ID" value="XM_028671162.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRE0"/>
    <dbReference type="GeneID" id="39730955"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00242700"/>
    <dbReference type="OMA" id="YILLPCI"/>
    <dbReference type="OrthoDB" id="7694678at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046923">
        <property type="term" value="F:ER retention sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006621">
        <property type="term" value="P:protein retention in ER lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000133">
        <property type="entry name" value="ER_ret_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10585">
        <property type="entry name" value="ER LUMEN PROTEIN RETAINING RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00810">
        <property type="entry name" value="ER_lumen_recept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00660">
        <property type="entry name" value="ERLUMENR"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10 12" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="28"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="115"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="204"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="240"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG95029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="284" mass="32819" checksum="21DDE0189C5E40DB" modified="2017-02-15" version="1">MKGVNDFIRKVNDTEKMKRYLSDHSSSIKIYCFFLFLVFIFYHLFSDGDFSFLLTLSSVISMFSFLMVFVKIEMNKSCAGVSLKMMECYVVLNTARLLSIVPFEGYLPYDKSGDWLYQLVEAISLFINCCIVYLCRYKYKNTYDNVNDIFNNLFLIIPAFIIAVFVHPSLNSFLPADVSWSFALYLESVCVLPQLSMFQKEGKVAAFTTHFLASQAFSKVLSFFFWIVSHKELNSSDNIIKSYVGLWVVIMQVVQLALMGDFIYHYIRCLSKGVSFDNLLNENV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRJ3</accession>
    <name>A0A1J1GRJ3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">U6 snRNA phosphodiesterase 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">3'-5' RNA exonuclease USB1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">USB1</name>
        <name evidence="7" type="ORF">PGAL8A_00255600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527964.1">
        <property type="nucleotide sequence ID" value="XM_028671297.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRJ3"/>
    <dbReference type="GeneID" id="39731084"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00255600"/>
    <dbReference type="OMA" id="YFCAYSV"/>
    <dbReference type="OrthoDB" id="49151at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034477">
        <property type="term" value="P:U6 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1140.10">
        <property type="entry name" value="Cyclic phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027521">
        <property type="entry name" value="Usb1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13522">
        <property type="entry name" value="U6 SNRNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13522:SF3">
        <property type="entry name" value="U6 SNRNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09749">
        <property type="entry name" value="HVSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="273" mass="32574" checksum="7D22EB11AE3409EC" modified="2017-02-15" version="1">MTNKGDFNVYIYIPVAYNEIIKKRSEYCYDILFKLINKQFNIYNVKSNQNDLFTKQNNELNKEEILKHIYYQIDNLNIDKKVQYDEKKDIEDSLHITIVGSVQIKRYMISSFINKVKEEMKNQNCFYLFFKKDVDLYKSQKNTKYFCSYSVNSEQQKLHLDPLIKKINKILNQFGLNNNYVNRICHVSLAYTDTSLETILEKNKLNVNDMFWPNINEIIIDNNSNHNTDDFYIYVNCIHVCIGNKLYKIHFKNFSNSNLLESDDFYVSSTDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS07</accession>
    <name>A0A1J1GS07_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00379200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526909.1">
        <property type="nucleotide sequence ID" value="XM_028670126.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS07"/>
    <dbReference type="GeneID" id="39732322"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00379200"/>
    <dbReference type="OMA" id="NILYFRM"/>
    <dbReference type="OrthoDB" id="365362at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="121"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1105"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1136"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1169"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1194"/>
            <end position="1211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1218"/>
            <end position="1237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="600"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="732"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="910"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="268"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="607"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1277" mass="151512" checksum="4E06D5264AFD6D94" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS41</accession>
    <name>A0A1J1GS41_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Inner membrane complex protein 1k, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">IMC1k</name>
        <name evidence="2" type="ORF">PGAL8A_00252900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527937.1">
        <property type="nucleotide sequence ID" value="XM_028671268.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS41"/>
    <dbReference type="GeneID" id="39731057"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00252900"/>
    <dbReference type="OMA" id="GYTHKFI"/>
    <dbReference type="OrthoDB" id="203824at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022086">
        <property type="entry name" value="IMCp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12314">
        <property type="entry name" value="IMCp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="73"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="477" mass="54602" checksum="AFCEE3F840C636C9" modified="2017-02-15" version="1">MEDSSDANYDPNKEINSMASRNENEILNINEYENKSGNGSRNESINGSKNESINGNRNESINGSRIESKKGSKNGSKNGSKNENENDSNFESENNIEFKGAKYIPDLHGLGKERQAITPKVQEIGIPGQVTPYHEPYDELNSEEATVYDENGLPITNNSNNTKDEKKLWSWTNDGKLKLSCSQPIIPVSVVQGILRRDKIILIPQVEVTDVVVPKIYNQNIKHDIPKLDIKVEDTRVKIPNVKYVDKEIIIPIITGYTHKFVPKWEVHEVPRPIVKYIGEQKIVEVEVPEIKYVDKIVEREVVVDTVEKRVPKIIEIPKYVDEVQYVWKPIEKIVYIQKLVPKFDVNLECPPPLIVPYPVQIVKQIPPVMVKKDTMIPEYQHYDLNSPEESVPIPEEYIKHYSKKQKFPKVCFSSCCESNVKNKENENEYIDVFPSYIKMDSTSFDNILNEPSYSKSLINDTKNILNESEQQVGVIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS99</accession>
    <name>A0A1J1GS99_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GMP synthase [glutamine-hydrolyzing]</fullName>
            <ecNumber evidence="2">6.3.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Glutamine amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">GMPS</name>
        <name evidence="13" type="ORF">PGAL8A_00388800</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.2" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527005.1">
        <property type="nucleotide sequence ID" value="XM_028670232.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS99"/>
    <dbReference type="GeneID" id="39732418"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00388800"/>
    <dbReference type="OMA" id="IWQSFAV"/>
    <dbReference type="OrthoDB" id="1724632at2759"/>
    <dbReference type="UniPathway" id="UPA00189">
        <property type="reaction ID" value="UER00296"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003921">
        <property type="term" value="F:GMP synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01997">
        <property type="entry name" value="GMP_synthase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.10:FF:000002">
        <property type="entry name" value="GMP synthase [glutamine-hydrolyzing]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00344">
        <property type="entry name" value="GMP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001674">
        <property type="entry name" value="GMP_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004739">
        <property type="entry name" value="GMP_synth_GATase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022955">
        <property type="entry name" value="GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025777">
        <property type="entry name" value="GMPS_ATP_PPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00884">
        <property type="entry name" value="guaA_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00888">
        <property type="entry name" value="guaA_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000848">
        <property type="entry name" value="PRK00074.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11922:SF2">
        <property type="entry name" value="GMP SYNTHASE [GLUTAMINE-HYDROLYZING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11922">
        <property type="entry name" value="GMP SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00958">
        <property type="entry name" value="GMP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00097">
        <property type="entry name" value="ANTSNTHASEII"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00096">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54810">
        <property type="entry name" value="GMP synthetase C-terminal dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51553">
        <property type="entry name" value="GMPS_ATP_PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="6 11" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="4 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 11" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMPS ATP-PPase" evidence="12">
        <location>
            <begin position="219"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="246"/>
            <end position="252"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG94184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="539" mass="62296" checksum="9CC51DF425E6E5F6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSC7</accession>
    <name>A0A1J1GSC7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">YTH domain-containing protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00009100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528135.1">
        <property type="nucleotide sequence ID" value="XM_028671487.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSC7"/>
    <dbReference type="GeneID" id="39728613"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00009100"/>
    <dbReference type="OMA" id="LNFNIWA"/>
    <dbReference type="OrthoDB" id="6103986at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990247">
        <property type="term" value="F:N6-methyladenosine-containing RNA reader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048024">
        <property type="term" value="P:regulation of mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21134">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.590.10">
        <property type="entry name" value="ph1033 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007275">
        <property type="entry name" value="YTH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045168">
        <property type="entry name" value="YTH_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12357:SF3">
        <property type="entry name" value="YTH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12357">
        <property type="entry name" value="YTH YT521-B HOMOLOGY DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04146">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50882">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YTH" evidence="1">
        <location>
            <begin position="23"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="277" mass="32750" checksum="22ADDD30092C496F" modified="2017-02-15" version="1">MNNNCSFVPPFHVVKNIYTNAKTKFFLIKSCSEKNICISLNYNIWATTPKNEKKFVNAFMEHEYVILIFSVNGSSKFCGYAIMQSKPGESKNKNVYFYYDNKIFRGKNFDIQWIRVVDVHFQEVSNLKNSLNENKPIKVGRDGQEIEQSAGVKLCEIFESNFVKMNILADTNQKKKPPTIYDINTNNSLGNNMDKNKEIINLYSLNNNFNMNYNTFRNLYEESQYNLFNFYNPSLHIFPIDLTNMNYDEYIYLYEKSQLLWQQKMLQMKSNFNCIKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSE8</accession>
    <name>A0A1J1GSE8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TPR Domain containing protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00011500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528159.1">
        <property type="nucleotide sequence ID" value="XM_028671514.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSE8"/>
    <dbReference type="GeneID" id="39728637"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00011500"/>
    <dbReference type="OMA" id="HKFELAN"/>
    <dbReference type="OrthoDB" id="2942533at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072380">
        <property type="term" value="C:TRC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006620">
        <property type="term" value="P:post-translational protein targeting to endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047150">
        <property type="entry name" value="SGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45831">
        <property type="entry name" value="LD24721P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45831:SF2">
        <property type="entry name" value="LD24721P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="289"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="43"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="111"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="350"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1074" mass="129653" checksum="B60D5AF5ADE07517" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSF0</accession>
    <name>A0A1J1GSF0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Transmission-blocking target antigen s230, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">P230</name>
        <name evidence="11" type="ORF">PGAL8A_00016000</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cell surface</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528202.1">
        <property type="nucleotide sequence ID" value="XM_028671562.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728682"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00016000"/>
    <dbReference type="OMA" id="EYTCDFT"/>
    <dbReference type="OrthoDB" id="369933at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2860">
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010884">
        <property type="entry name" value="6_CYS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038160">
        <property type="entry name" value="6_CYS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051444">
        <property type="entry name" value="Parasite_Repro/Invasion_Surf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38796">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38796:SF1">
        <property type="entry name" value="ANCHORED PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G09600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07422">
        <property type="entry name" value="s48_45"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00970">
        <property type="entry name" value="s48_45"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51701">
        <property type="entry name" value="6_CYS"/>
        <property type="match status" value="13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="6-Cys" evidence="10">
        <location>
            <begin position="453"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="10">
        <location>
            <begin position="597"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="10">
        <location>
            <begin position="753"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="10">
        <location>
            <begin position="960"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="10">
        <location>
            <begin position="1105"/>
            <end position="1252"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="10">
        <location>
            <begin position="1255"/>
            <end position="1378"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="10">
        <location>
            <begin position="1512"/>
            <end position="1697"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="10">
        <location>
            <begin position="1700"/>
            <end position="1829"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="10">
        <location>
            <begin position="1986"/>
            <end position="2154"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="10">
        <location>
            <begin position="2191"/>
            <end position="2395"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="10">
        <location>
            <begin position="2398"/>
            <end position="2542"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="10">
        <location>
            <begin position="2555"/>
            <end position="2691"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="10">
        <location>
            <begin position="2694"/>
            <end position="2838"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="254"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="265"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="278"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="327"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="339"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG95391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2847" mass="328627" checksum="EEE36220825F12CD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSR8</accession>
    <name>A0A1J1GSR8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00007000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528115.1">
        <property type="nucleotide sequence ID" value="XM_028671465.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSR8"/>
    <dbReference type="GeneID" id="39728592"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00007000"/>
    <dbReference type="OMA" id="SNYMKAS"/>
    <dbReference type="OrthoDB" id="372216at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="567" mass="66927" checksum="6B02C94E7C4D88E8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTA7</accession>
    <name>A0A1J1GTA7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00266800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000036">
        <property type="protein sequence ID" value="CRG95465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528275.1">
        <property type="nucleotide sequence ID" value="XM_028671642.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTA7"/>
    <dbReference type="GeneID" id="39731197"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00266800"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012565853" evidence="3">
        <location>
            <begin position="23"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="241"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="159"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="276" mass="32850" checksum="3CA52DF77BAA9F2A" modified="2017-02-15" version="1">MKTLTLYLKITTFLLLIWMYECFYNCDSYKTLIDKNILQIKNVLKYERVLTEGDIAGEKQTNAEGCQEECPLDNEKNKCNNPVQYKNQCDPHHGVKTPSLWESFDKKAKEIDPKLREQELNIELRKISHENVDPFSKIYQRHNPDEGRQILILSVTKDHSDLKKLLDECRKEKRDNKAESECKKEIEENKTELESKKLMIDNKTELESMKEMKENKTESESKNDMRDNITEFEWMNEMIKNETECESEPENEMRENKKKNKKSNILKFLFCCCDNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTB2</accession>
    <name>A0A1J1GTB2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00273300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528345.1">
        <property type="nucleotide sequence ID" value="XM_028671720.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTB2"/>
    <dbReference type="GeneID" id="39731265"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00273300"/>
    <dbReference type="OMA" id="REWINLR"/>
    <dbReference type="OrthoDB" id="10566831at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="293" mass="34726" checksum="06D6A1FB46D3CFA5" modified="2017-02-15" version="1">MKYYNIVTSNFPKGDSISNNTITRKYRNNFFKYSNDTMEKKNYLNLKFYRFTFCLYKSHRNILIEIHSNKYYSRILSQQSRNQGRMGNQNGIYQSALIFKGLRESFSNEKRMILLGMIFGMRNELMLCPSLSIFPRSLKHDIWGKWTDYSNTIISIIEKDEREDFNKAERDGYSVNECIRLTKLYIAKWSKTRLQLSESYFLFLRYALALYKKTWSSDRNSPRVRNGENILFKGTLGIPNTETFILPNGKLVMVTDNSINITENKKNIFYSPTVQEELHNLRKSLQVKQEILN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTB5</accession>
    <name>A0A1J1GTB5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00293500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528538.1">
        <property type="nucleotide sequence ID" value="XM_028671935.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTB5"/>
    <dbReference type="GeneID" id="39731468"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00293500"/>
    <dbReference type="OrthoDB" id="392697at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="451"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="614"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="159"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="451"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="487"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="615"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="644"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="657"/>
            <end position="668"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="668" mass="80802" checksum="D209C8E595002A76" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTF8</accession>
    <name>A0A1J1GTF8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00271500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000041">
        <property type="protein sequence ID" value="CRG95514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528323.1">
        <property type="nucleotide sequence ID" value="XM_028671696.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTF8"/>
    <dbReference type="GeneID" id="39731246"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00271500"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="191" mass="22276" checksum="D345486BD3DCD4E0" modified="2017-02-15" version="1">MEFPLFTVDNEKCKIDLNIKSNFQNSNNNLMNRVNLNGCPEPLYQETPPKFLMKNRKEKNDNINKNNIVDNEKCKIDLNIKSNFQNSNNNLMNRVNLNGCPEPLYQETPPKFLMKNRKEKNDKINESNLVDNEKCKIDLNIKSNFQNSNNNLVNRVDLNGCPEPLYQETPPKFLMNCSLFVYTLILDLKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTK3</accession>
    <name>A0A1J1GTK3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Poly(A)-specific ribonuclease PARN, putative</fullName>
            <ecNumber evidence="3">3.1.13.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PARN</name>
        <name evidence="3" type="ORF">PGAL8A_00202700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.4" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527445.1">
        <property type="nucleotide sequence ID" value="XM_028670720.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTK3"/>
    <dbReference type="GeneID" id="39730553"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00202700"/>
    <dbReference type="OMA" id="CHYILRK"/>
    <dbReference type="OrthoDB" id="414075at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004535">
        <property type="term" value="F:poly(A)-specific ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051181">
        <property type="entry name" value="CAF1_poly(A)_ribonucleases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006941">
        <property type="entry name" value="RNase_CAF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15092">
        <property type="entry name" value="POLY A -SPECIFIC RIBONUCLEASE/TARGET OF EGR1, MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15092:SF22">
        <property type="entry name" value="POLY(A)-SPECIFIC RIBONUCLEASE PNLDC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04857">
        <property type="entry name" value="CAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="441"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="810" mass="96361" checksum="51FBE7A82CA2856A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTN6</accession>
    <name>A0A1J1GTN6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial import inner membrane translocase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00306200</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tim17/Tim22/Tim23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528658.1">
        <property type="nucleotide sequence ID" value="XM_028672068.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTN6"/>
    <dbReference type="GeneID" id="39731595"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00306200"/>
    <dbReference type="OMA" id="FRIVEDC"/>
    <dbReference type="OrthoDB" id="2261329at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005744">
        <property type="term" value="C:TIM23 mitochondrial import inner membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10485:SF0">
        <property type="entry name" value="AT05822P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10485">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG95850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="162" mass="17839" checksum="6F14D12107E362F1" modified="2017-02-15" version="1">MLQERDLAREPCPDRIIEDMGGAFGMGCVGGYIWHFLKGARNSPKGDILSGALYSSRMRAPILGGNFAVWGGTFSCFDCAFQYVRKKEDHWNAIGSGFCTGGVLAMRGGWRSASRNAIVGGVLLAIIEVVSIVLTRKTTPTPRQQFQQQMEMEKRMASKNNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTP6</accession>
    <name>A0A1J1GTP6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Hpc2-related domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00207500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527493.1">
        <property type="nucleotide sequence ID" value="XM_028670774.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730602"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00207500"/>
    <dbReference type="OMA" id="DIDICRI"/>
    <dbReference type="OrthoDB" id="361447at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014840">
        <property type="entry name" value="HRD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08729">
        <property type="entry name" value="HUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hpc2-related" evidence="3">
        <location>
            <begin position="272"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="444"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="635"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1073"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1220"/>
            <end position="1279"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="352"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="447"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="644"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1073"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1230"/>
            <end position="1277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1365" mass="161024" checksum="7F89D8AE5B40E8FF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU01</accession>
    <name>A0A1J1GU01_PLAGA</name>
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        <submittedName>
            <fullName evidence="1">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00322000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
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            <taxon>Plasmodium</taxon>
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    </organism>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000049">
        <property type="protein sequence ID" value="CRG96006.1"/>
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    </dbReference>
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    <dbReference type="OrthoDB" id="6475849at2759"/>
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    </dbReference>
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        <property type="entry name" value="CHP01606_Plasmodium_spp"/>
    </dbReference>
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        <property type="entry name" value="Wx5_PLAF3D7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="196" mass="23621" checksum="5AE8E3E00D967A86" modified="2017-02-15" version="1">MDIFIYLYNVGDSYKILIDKNRLQIKNELKYERVLTEGDIGGKKQSYGEECLEECPLDNKKNKWENPVRYENPYDNWNKVITPFLREEFNKETGGMDPEWREQKWNNEWNNISANKVNELSSIYMRSIPKKDKEKLICCVEQKLFTLFVEFLDKCKKEMRDNKTESESKKEKLKKILHLEKLYFTIIKEIIIKNIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU56</accession>
    <name>A0A1J1GU56_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00323100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000050">
        <property type="protein sequence ID" value="CRG96018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528826.1">
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    </dbReference>
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    <dbReference type="GeneID" id="39731764"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00323100"/>
    <dbReference type="Proteomes" id="UP000220797">
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    </dbReference>
    <proteinExistence type="predicted"/>
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        </location>
    </feature>
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            <end position="61"/>
        </location>
    </feature>
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            <begin position="71"/>
            <end position="84"/>
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    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="85"/>
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            <begin position="98"/>
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    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
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            <begin position="134"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <begin position="159"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="181" mass="21679" checksum="DD6DFFC48B23C24C" modified="2017-02-15" version="1">MSSRLLKKFLKEKNRDEINKISETVKGQSIKLKKKKNFFKYLEDSVTSENSNEENNNEENNNEQNNNEQNNNEKRLDDYERTNTIEKSSLLENSNKSISDKNKQDIYKEKKKYKISEEINIVKEDLENQEKTNRTSKKNKKKKKKKNIDEEISSILNKINKEEKKGQEEKKEKEKEKDKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU89</accession>
    <name>A0A1J1GU89_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Kelch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00227500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
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    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00227500"/>
    <dbReference type="OMA" id="GSFIMMG"/>
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    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
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    </dbReference>
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        <property type="entry name" value="HATPase_C_sf"/>
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    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF18">
        <property type="entry name" value="FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="141"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="486"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1425"/>
            <end position="1579"/>
        </location>
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        </location>
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        </location>
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        </location>
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    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="141"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
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            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
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        </location>
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        </location>
    </feature>
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        </location>
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        </location>
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            <begin position="1510"/>
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        <location>
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            <end position="1559"/>
        </location>
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    </feature>
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        </location>
    </feature>
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        </location>
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        <location>
            <begin position="1985"/>
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        </location>
    </feature>
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        <location>
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        </location>
    </feature>
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        </location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="2679"/>
            <end position="2702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="2735"/>
            <end position="2750"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2750" mass="321063" checksum="47500050F9E76F8C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUG7</accession>
    <name>A0A1J1GUG7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L36</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPL36</name>
        <name evidence="5" type="ORF">PGAL8A_00336900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528956.1">
        <property type="nucleotide sequence ID" value="XM_028672400.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUG7"/>
    <dbReference type="GeneID" id="39731899"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00336900"/>
    <dbReference type="OMA" id="NKGHKTE"/>
    <dbReference type="OrthoDB" id="25649at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1760:FF:000001">
        <property type="entry name" value="60S ribosomal protein L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1760">
        <property type="entry name" value="60S ribosomal protein L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000509">
        <property type="entry name" value="Ribosomal_eL36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038097">
        <property type="entry name" value="Ribosomal_eL36_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10114">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01158">
        <property type="entry name" value="Ribosomal_L36e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01190">
        <property type="entry name" value="RIBOSOMAL_L36E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="112" mass="12827" checksum="9C04FF59BFD9F7B5" modified="2017-02-15" version="1">MGRKSSTKPSTGIAVGFNSGHIVTKRNLKINKKKKQPSKRKEFIKDVVREITGFSPYEKRLIELIKIGTSASIKRSLKYAKKKLGTHKRGKAKREEIQKIVMIQRRKAAEKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUI4</accession>
    <name>A0A1J1GUI4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sexual stage-specific protein G37</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00317400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528769.1">
        <property type="nucleotide sequence ID" value="XM_028672191.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUI4"/>
    <dbReference type="GeneID" id="39731707"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00317400"/>
    <dbReference type="OMA" id="GYLYMSL"/>
    <dbReference type="OrthoDB" id="387086at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013131286" description="Sexual stage-specific protein G37" evidence="2">
        <location>
            <begin position="20"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="261"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="303"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="348" mass="39815" checksum="537165E404D4B16F" modified="2017-02-15" version="1">MKSLTFIFLLFVIFKKNLVENIIQKQDVYLDDEFKSFTYFFASSPSANFLSRIVHSDNSRFAQVKNKADILGKTIDKVYSINQVSSVIMKVYITLLLLFLLPYFAYIGIFGYTRDQVTLTLSSILAYFALLIVFYLTNGILSIGFVCSLPLVFGLTIFHLAKSDCTTKALYKNVRYIFCFILAKLIYDIGTNLSGNESNSFDYGFSGLIYMNILKGNNYIILKIVHLMVLSFIALIIIKLFSKLFSNNSPQSPMLMQSDRYIISFLCSLPIATCFTQIFYLIYKTLNPIDPSIFFMIPSSIKFTSISTTFSLITWVIVTYVLNVLRNLVETDYNHILNKLPSNISEFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUI5</accession>
    <name>A0A1J1GUI5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00333700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528927.1">
        <property type="nucleotide sequence ID" value="XM_028672368.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUI5"/>
    <dbReference type="GeneID" id="39731867"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00333700"/>
    <dbReference type="OMA" id="RGNIKCT"/>
    <dbReference type="OrthoDB" id="369768at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="113" mass="13760" checksum="E7DB165197E3CF78" modified="2017-02-15" version="1">MKTSKDLCKFFCKKCNNFIFYKEACDLIFEKIYPQYSKLYYNKYVLDKKKVNENNVKIYDNLYRQIYSNGLCGVNKQRNCFLNKDNIYNILSYLNKGNIECKKCNKINMWYIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV58</accession>
    <name>A0A1J1GV58_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00363100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529212.1">
        <property type="nucleotide sequence ID" value="XM_028672684.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV58"/>
    <dbReference type="GeneID" id="39732161"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00363100"/>
    <dbReference type="OMA" id="NYSVINI"/>
    <dbReference type="OrthoDB" id="363455at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="348" mass="42580" checksum="41865D58DFE08BFD" modified="2017-02-15" version="1">MIFKRCFHKYPGGSKIKCYIEKKKKKRLGVSLFHQPLYSKNSKNYIDWRYCTPKSGYEYMYIYGENTIEITNLPNNKTNEYIQERLRKSLNKYGRLKIIRCLSNKNDPYINNNICYATFLNKRDMYKCIRNVNIRFPLSLQYKILKFKSLYTNKKNDYNYFFKQEHYNYSSINIALNLFKYLQFNNCMINIKNIYKHIYEYSFYPYKIITSGISIYKVFNNWINFINFFDNLFMKINKNNEIFICSKIIDDQNLRIYLNNKLIELKKKTNISNSVYWRNDSLQLPEEIENKLNNDHPKKLKEELQLLSKTKDFYKIHDERHLFKLKLNKERKEKKLLKKKNEKLKESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV81</accession>
    <name>A0A1J1GV81_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00234400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527760.1">
        <property type="nucleotide sequence ID" value="XM_028671070.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV81"/>
    <dbReference type="GeneID" id="39730871"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00234400"/>
    <dbReference type="OMA" id="VWFTIND"/>
    <dbReference type="OrthoDB" id="387525at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="440"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="450"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="459" mass="55361" checksum="E49F0047EAA79F07" modified="2017-02-15" version="1">MEKKENEDKTENYFDKITNFFNYFTLDNSQNEEQTVVSPEIMNNKNEINQDNRDSVKQVVYNLKLKRASVSNIPQRLILDTLINSKKDVNNKININDNFTVDTITKDCEENNSNKIREKNSSLIILDKDKESKNNFSYSPSFHYNKDELFHLNKRKNDKKEENKKKKKDKVKKNKKELKEKGIEEYMNIDESYTNEKKEKTKRREKNKCKKNEVNNQEEEREKEEKKEKKEIKEKEEKKEKEEKKEKEEKKEKEEKKEKEEEKEKKEIREKEEKKEKQVQEIQEKKNKKTDKKKIKESYEENYESRLIKRKENQDIKNKNISIELPSIKNSNDSNYLYDEKVQFLENKNFKENIKNNKEIIKNKISLDSSTLNEKNIFDDNKKYIRIRNRKKRDNVIILPKLNLNQKCESFSTEEKKKKNQDILINNKSCNINNVIQDNDDKTTVSGQSDEDKNELMNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVD4</accession>
    <name>A0A1J1GVD4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ribose-phosphate diphosphokinase</fullName>
            <ecNumber evidence="3">2.7.6.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00240000</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ribose-phosphate pyrophosphokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.1" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527816.1">
        <property type="nucleotide sequence ID" value="XM_028671134.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVD4"/>
    <dbReference type="GeneID" id="39730928"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00240000"/>
    <dbReference type="OMA" id="EFWIRMK"/>
    <dbReference type="OrthoDB" id="413572at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002189">
        <property type="term" value="C:ribose phosphate diphosphokinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006015">
        <property type="term" value="P:5-phosphoribose 1-diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000031">
        <property type="entry name" value="Probable PRS4-ribose-phosphate pyrophosphokinase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210:SF32">
        <property type="entry name" value="RIBOSE-PHOSPHATE PYROPHOSPHOKINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14572">
        <property type="entry name" value="Pribosyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01400">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribose-phosphate pyrophosphokinase N-terminal" evidence="10">
        <location>
            <begin position="176"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="386"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG95003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="585" mass="67319" checksum="3D9F5816D2B5BCEE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVJ7</accession>
    <name>A0A1J1GVJ7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cupin-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00348800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529075.1">
        <property type="nucleotide sequence ID" value="XM_028672531.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVJ7"/>
    <dbReference type="GeneID" id="39732018"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00348800"/>
    <dbReference type="OMA" id="PASWWHE"/>
    <dbReference type="OrthoDB" id="415358at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000146">
        <property type="entry name" value="Cupin-like protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461:SF100">
        <property type="entry name" value="JMJC DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="2">
        <location>
            <begin position="123"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="253"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="443" mass="53411" checksum="E92180FDC167DF55" modified="2017-02-15" version="1">MALKNEYSGFCFHKQKLNKIDRIDKNISAEQFYLDYVLKRKPCLLKSEYIIGERCNIDINFMKENVENSYVELEQKVSNSFGIGKKKKMKFHKFLSLIEKGDSNYYLNTQYIKENPYGPTDFCNSITRQMINFLPKKLKIMGNLEIYQYNIWLGNNEDKNLKTFLHHDYHDNIYVLLKGKKIFRIYSPNFAYDLKTNGNINRIYNNGLITYSPFIRSDGSHYFDVYKKKIDKVYSDINTMNEHLNKENNLIEDKIIEKCINKAEKKLNKLENNILDYKLRKSKFQYKEKKRNDIPNHFCILNTTERKYELDIFNDNTDIKQKYIEVCMNEEDILYLPCGWFHEVKSFSGEKYHLAFNYWYYPPYIKMNSSGEAQNRFCHPYVDKYLSERNKNLYKKIGIFIKENVPNIKDILSYYINYDTKKCKKIKRKKIKRFSQKKRIKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVP2</accession>
    <name>A0A1J1GVP2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00361200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529193.1">
        <property type="nucleotide sequence ID" value="XM_028672663.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVP2"/>
    <dbReference type="GeneID" id="39732142"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00361200"/>
    <dbReference type="OMA" id="EICECET"/>
    <dbReference type="OrthoDB" id="206452at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15457">
        <property type="entry name" value="NADAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.40">
        <property type="entry name" value="YbiA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050923">
        <property type="entry name" value="Cell_Proc_Reg/RNA_Proc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012816">
        <property type="entry name" value="NADAR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037238">
        <property type="entry name" value="YbiA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23308">
        <property type="entry name" value="NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143990">
        <property type="entry name" value="YbiA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="312"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="543"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="595"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="556"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="595"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="657"/>
            <end position="676"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="676" mass="81578" checksum="CC29B6EA2B533155" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVR7</accession>
    <name>A0A1J1GVR7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00423000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529454.1">
        <property type="nucleotide sequence ID" value="XM_028672952.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732762"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00423000"/>
    <dbReference type="OMA" id="HKNYENH"/>
    <dbReference type="OrthoDB" id="372722at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1632"/>
            <end position="1870"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1887"/>
            <end position="1987"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1641"/>
            <end position="1660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1676"/>
            <end position="1695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1696"/>
            <end position="1707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1708"/>
            <end position="1747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1748"/>
            <end position="1865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1892"/>
            <end position="1958"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1962"/>
            <end position="1987"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2308" mass="278363" checksum="0D93C766529EA95A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVT5</accession>
    <name>A0A1J1GVT5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sporozoite protein essential for cell traversal, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SPECT1</name>
        <name evidence="3" type="ORF">PGAL8A_00253600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527944.1">
        <property type="nucleotide sequence ID" value="XM_028671275.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVT5"/>
    <dbReference type="GeneID" id="39731064"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00253600"/>
    <dbReference type="OMA" id="FKKMCDL"/>
    <dbReference type="OrthoDB" id="377537at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040897">
        <property type="entry name" value="SPECT1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18680">
        <property type="entry name" value="SPECT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012723829" evidence="1">
        <location>
            <begin position="20"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="Plasmodium host cell traversal SPECT1" evidence="2">
        <location>
            <begin position="59"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="242" mass="28572" checksum="E5F48392AFC8F640" modified="2017-02-15" version="1">MKHKIYLFFFLTLLKYALSLRLNNTLSKKNNFVAEKYFRKENDNENLKFQIIDDLEKINEEFSNDVNTAKIFVRDTFLDTEASFKEISDDVVKIISKYSFSIDEKLNVLNGLLQEFIENNKSSIFNSSDENMISHKNKIKEVSDSILCKLKKLIELNIFNKYHAILKFGNQNIKNETLEALRIERKLSDKLKKELLKYKTLENEDIKESESTNFLKSVYNKFIVKLDEIINEMSKELSHILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW81</accession>
    <name>A0A1J1GW81_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GPN-loop GTPase 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00430600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Binds to RNA polymerase II (RNAPII).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the GPN-loop GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529530.1">
        <property type="nucleotide sequence ID" value="XM_028673037.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW81"/>
    <dbReference type="GeneID" id="39732838"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00430600"/>
    <dbReference type="OMA" id="ATHNYFL"/>
    <dbReference type="OrthoDB" id="5839at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17871">
        <property type="entry name" value="GPN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000338">
        <property type="entry name" value="GPN-loop GTPase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004130">
        <property type="entry name" value="Gpn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030231">
        <property type="entry name" value="Gpn2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231:SF3">
        <property type="entry name" value="GPN-LOOP GTPASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231">
        <property type="entry name" value="XPA-BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03029">
        <property type="entry name" value="ATP_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="332" mass="38523" checksum="3D0EBFE09966EB32" modified="2017-02-15" version="1">MWYGQLVIGPPGSGKSTYVAGVDHILKQINRKTLIVNLDPFIENDIYKGDINISELVDINKVFSDLELGPNGTLIYCMEYLLANFDWLEEKLKEHKDCYLIIDTPGQVELYTHNDALKNIVHKLSKLNCRLASVHIVDSTLCSDNYKYISSLLLSLCSQIHLELPHVNVFSKIDLLKYFKNDLKFPLSYYVEAQNLNQLMLYAKYQNYSSSDSEDDYIYNIKNNLNDANIKNTKKNYNKYSKKFLKLNEYICETVEDYNLINFALLDIQDKYSVLKLLKIIDGANGFRFSSIYSEYSLFDTYVESIEYDCDDIQEKVIDVSDNEILKSFNDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWB7</accession>
    <name>A0A1J1GWB7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">tRNA m2G10 methyltransferase subunit, putative</fullName>
            <ecNumber evidence="2">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00279400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRM112 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528405.1">
        <property type="nucleotide sequence ID" value="XM_028671787.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWB7"/>
    <dbReference type="GeneID" id="39731327"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00279400"/>
    <dbReference type="OMA" id="NMLTSKC"/>
    <dbReference type="OrthoDB" id="2187549at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070476">
        <property type="term" value="P:rRNA (guanine-N7)-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21089">
        <property type="entry name" value="Trm112-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039127">
        <property type="entry name" value="Trm112"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005651">
        <property type="entry name" value="Trm112-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12773:SF0">
        <property type="entry name" value="MULTIFUNCTIONAL METHYLTRANSFERASE SUBUNIT TRM112-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12773">
        <property type="entry name" value="UPF0315 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03966">
        <property type="entry name" value="Trm112p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158997">
        <property type="entry name" value="Trm112p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="125" mass="14316" checksum="2AB91B7E79243E0F" modified="2017-02-15" version="1">MRLLTHNFLKCNETQCTEGYPLIIKLDNNSEENIKILDQEMNIEFVKNVLSKVDYDVLYNTAKQLGINLLSSYSSEHLENEEFLNSIHHALFKVHIMEGTLVCPKCSISFPIKDGIPNMLTGNEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWP1</accession>
    <name>A0A1J1GWP1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00444100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529663.1">
        <property type="nucleotide sequence ID" value="XM_028673184.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWP1"/>
    <dbReference type="GeneID" id="39732974"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00444100"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="8"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="532" mass="65011" checksum="293CA41C1C77CBBB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWW9</accession>
    <name>A0A1J1GWW9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Dihydrolipoyl dehydrogenase</fullName>
            <ecNumber evidence="11">1.8.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">LPD1</name>
        <name evidence="14" type="ORF">PGAL8A_00453900</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + NAD(+) = N(6)-[(R)-lipoyl]-L-lysyl-[protein] + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15045"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="1.8.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9 11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="9 11">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="11">The active site is a redox-active disulfide bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.4" evidence="11"/>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529762.1">
        <property type="nucleotide sequence ID" value="XM_028673294.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWW9"/>
    <dbReference type="GeneID" id="39733072"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00453900"/>
    <dbReference type="OMA" id="CAQLGMK"/>
    <dbReference type="OrthoDB" id="361797at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045252">
        <property type="term" value="C:oxoglutarate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004148">
        <property type="term" value="F:dihydrolipoyl dehydrogenase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006103">
        <property type="term" value="P:2-oxoglutarate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.30:FF:000001">
        <property type="entry name" value="Dihydrolipoyl dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050151">
        <property type="entry name" value="Class-I_Pyr_Nuc-Dis_Oxidored"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006258">
        <property type="entry name" value="Lipoamide_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01350">
        <property type="entry name" value="lipoamide_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22912:SF223">
        <property type="entry name" value="DIHYDROLIPOYL DEHYDROGENASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22912">
        <property type="entry name" value="DISULFIDE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="FAD/NAD-linked reductases, dimerisation (C-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 9 11" id="KW-0274">FAD</keyword>
    <keyword evidence="2 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 9 11" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 11 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7 11" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="13">
        <location>
            <begin position="21"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridine nucleotide-disulphide oxidoreductase dimerisation" evidence="12">
        <location>
            <begin position="389"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="487"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="160"/>
            <end position="162"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="214"/>
            <end position="221"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="306"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="348"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="354"/>
            <end position="357"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="10">
        <location>
            <begin position="59"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG96959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="508" mass="56829" checksum="AA5A3836217B90DA" modified="2017-02-15" version="1">MGKVRTLFSPFRRGFSTKMDYDVIVIGGGPGGYVCSIRCGQHKLKVLNINEDKKLGGTCLNRGCIPSKSLLHIAHNYYEAKNRFKDSGILIDNINIDIDTIHKHKNKCMGNLADGISFLYKKNNVNHIIGHGSIIDENTVLVKSEKEEKKITAERIVIATGSKPIEIPLKKLNDNNLDDIDNVTDILEYDHEIIQNSDDILNFKKIPKKMSIIGGGVIGIEIGSVFSKLGSDVTIFEYNDRLCTFLDADVSKVLQKTLEKIKMKFKFNTSIIGANIINNEAILFCKNNKTNEIKKVKSEVVLICVGRKANLENLNLHNLNIELNKNKKIQVDEYFNVTPFSTIKAIGDVIDGPMLAHKAEEEGYIVANMLFSELKKNKKKKSHINHDLVPSVIYTHPEVASVGYNEEKCKKLNINFKSVSFPFAANSRARTIDDYDGLIKLIVEKDTNKILGSQIIGNNASDLILPISIYVSNNGSSKSLSKIIYPHPTFSEVIKEVALHSFDKPIHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWX7</accession>
    <name>A0A1J1GWX7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glucose inhibited division protein a homologue, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00464700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529870.1">
        <property type="nucleotide sequence ID" value="XM_028673415.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWX7"/>
    <dbReference type="GeneID" id="39733180"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00464700"/>
    <dbReference type="OMA" id="ACAEVKY"/>
    <dbReference type="OrthoDB" id="3329at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000082">
        <property type="entry name" value="protein MTO1 homolog, mitochondrial isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000255">
        <property type="entry name" value="tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.570">
        <property type="entry name" value="GidA associated domain, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002218">
        <property type="entry name" value="MnmG-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026904">
        <property type="entry name" value="MnmG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047001">
        <property type="entry name" value="MnmG_C_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044920">
        <property type="entry name" value="MnmG_C_subdom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040131">
        <property type="entry name" value="MnmG_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806">
        <property type="entry name" value="GLUCOSE INHIBITED DIVISION PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806:SF0">
        <property type="entry name" value="PROTEIN MTO1 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01134">
        <property type="entry name" value="GIDA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13932">
        <property type="entry name" value="SAM_GIDA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01228">
        <property type="entry name" value="GIDA_assoc_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA uridine 5-carboxymethylaminomethyl modification enzyme C-terminal subdomain" evidence="5">
        <location>
            <begin position="819"/>
            <end position="892"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="900" mass="103702" checksum="B995203B86B5D9FD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWZ7</accession>
    <name>A0A1J1GWZ7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00454400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529767.1">
        <property type="nucleotide sequence ID" value="XM_028673300.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWZ7"/>
    <dbReference type="GeneID" id="39733077"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00454400"/>
    <dbReference type="OMA" id="AKWSGYE"/>
    <dbReference type="OrthoDB" id="364513at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="835" mass="99746" checksum="BBA4D9D4D82393B1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX76</accession>
    <name>A0A1J1GX76_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00449100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000072">
        <property type="protein sequence ID" value="CRG96910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529713.1">
        <property type="nucleotide sequence ID" value="XM_028673240.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX76"/>
    <dbReference type="GeneID" id="39733024"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00449100"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="80" mass="9074" checksum="1E9D868CCCCDA4A8" modified="2017-02-15" version="1">MSPEENRNITGHMAFLNDPKPYKIFIAFSAINIIPLIIGVILIIYICRICWEERGTNYNADNLSIDSGYGGRSIDRLDII</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX92</accession>
    <name>A0A1J1GX92_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">N-alpha-acetyltransferase 15, NatA auxiliary subunit, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00464800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529871.1">
        <property type="nucleotide sequence ID" value="XM_028673416.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX92"/>
    <dbReference type="GeneID" id="39733181"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00464800"/>
    <dbReference type="OMA" id="IFPHHNY"/>
    <dbReference type="OrthoDB" id="10263032at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1010">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1040">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021183">
        <property type="entry name" value="NatA_aux_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22767:SF2">
        <property type="entry name" value="N(ALPHA)-ACETYLTRANSFERASE 15_16, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22767">
        <property type="entry name" value="N-TERMINAL ACETYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12569">
        <property type="entry name" value="NatA_aux_su"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="85"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="639"/>
            <end position="658"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1219" mass="146509" checksum="C7B5E76222647AD6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXH6</accession>
    <name>A0A1J1GXH6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Clustered-asparagine-rich protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00457800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529801.1">
        <property type="nucleotide sequence ID" value="XM_028673339.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXH6"/>
    <dbReference type="GeneID" id="39733111"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00457800"/>
    <dbReference type="OMA" id="KHSQWNK"/>
    <dbReference type="OrthoDB" id="410044at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12362">
        <property type="entry name" value="RRM3_CELF1-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000237">
        <property type="entry name" value="CUGBP Elav-like family member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21245">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="16"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="4">
        <location>
            <begin position="255"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="303"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="212"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="388" mass="45260" checksum="077FBD1B9BA511BD" modified="2017-02-15" version="1">MSNEILNSTIDGVLNTRLHIQNIPPHITDVHLRSLLGNVGYIKDICYFNKNKKQMNNFTNKKIYNTALITFNTHEEALNVLKNIRSLIDTTGEERSIEAKFAVPNVNNNFFHKNNMNANFPNNYQNNFNNENFSNNMNNYNFYNNNNNSNSQNNFMNRNVKNKNINNMVNMNMNNQVNNPMANQNNFMFNNNNYNGNKNMNEMIRESESPPNNNNNNNNALYRQNNSQVSNSNNVYQTNDNSLDENENTEGLSLWEIYKDKNNNTFYYNNLTKHSQWNKPIHPNKLFQYNNNEKTKQNGPNGSNLFIFHIPSEWSDLDLFQHFCCFGNIISSKIQRDNTGRNSGFGFVSYDNIMSAHHAIQFMNGYYVNNKYLKVQLKKGEAMEKVQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXJ7</accession>
    <name>A0A1J1GXJ7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Palmitoyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">DHHC10</name>
        <name evidence="9" type="ORF">PGAL8A_00487100</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530094.1">
        <property type="nucleotide sequence ID" value="XM_028673664.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXJ7"/>
    <dbReference type="GeneID" id="39733404"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00487100"/>
    <dbReference type="OMA" id="SYCEVCE"/>
    <dbReference type="OrthoDB" id="331948at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12246">
        <property type="entry name" value="PALMITOYLTRANSFERASE ZDHHC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="14"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="155"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="192"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="8">
        <location>
            <begin position="107"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG97292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="277" mass="33003" checksum="677ED5E090F52EDE" modified="2017-02-15" version="1">MKEINKSERDIRQLLPVMLIGFVTIVMYTIFVTFYCMVLLQINVEKQYVDNNLLKEGYTKLITFHILLFLLIWSFYKTCRVDPGTIPDTHEWLVEPDVNRINEREQTGELRFCIHEQKYKPDRAHYCRAIKKNVLKMDHYCPWVANCVGFYNYKFFLLSLFYANLCCFYVEINCHSSFPDFNSNPNVLFNEVFYLFLEIVLTSVILLIIFPFFLFHLYLTSKNYTTLEFCVIGQKNKKNIYDLEIEENFKQVLGDNILFWFLPVGKPKGDGLFFKTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXX8</accession>
    <name>A0A1J1GXX8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00489600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530119.1">
        <property type="nucleotide sequence ID" value="XM_028673692.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXX8"/>
    <dbReference type="GeneID" id="39733429"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00489600"/>
    <dbReference type="OrthoDB" id="349484at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="848" mass="99690" checksum="DB036FF1B70E3AC8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY70</accession>
    <name>A0A1J1GY70_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Prokaryotic-type class I peptide chain release factors domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00344200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529029.1">
        <property type="nucleotide sequence ID" value="XM_028672481.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY70"/>
    <dbReference type="GeneID" id="39731972"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00344200"/>
    <dbReference type="OMA" id="NVDTAKW"/>
    <dbReference type="OrthoDB" id="270639at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:peptidyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016150">
        <property type="term" value="F:translation release factor activity, codon nonspecific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070126">
        <property type="term" value="P:mitochondrial translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052104">
        <property type="entry name" value="Mito_Release_Factor_mL62"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11075:SF54">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN ML62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11075">
        <property type="entry name" value="PEPTIDE CHAIN RELEASE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110916">
        <property type="entry name" value="Peptidyl-tRNA hydrolase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00745">
        <property type="entry name" value="RF_PROK_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prokaryotic-type class I peptide chain release factors" evidence="2">
        <location>
            <begin position="25"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="93"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="153" mass="18063" checksum="DDDFB574FB84F52A" modified="2017-02-15" version="1">MFALSKKWLLSFEIPYGQIQKITARSSGPGGQSVNKAETKVQLRFNINEANWIPSNVKENLKKIYKNKLSKCNDLIIECEETSSQISNYKICIEKLKLILEEAENYKERVKNTSVKDYIHLIKSKEQIKKYKDNLINQKKKKRERKFNKKDYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYD1</accession>
    <name>A0A1J1GYD1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00514300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530371.1">
        <property type="nucleotide sequence ID" value="XM_028673971.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYD1"/>
    <dbReference type="GeneID" id="39733676"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00514300"/>
    <dbReference type="OMA" id="RYSHDRM"/>
    <dbReference type="OrthoDB" id="376083at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="191" mass="22017" checksum="1417801E322FB825" modified="2017-02-15" version="1">MSSFKFLSTRVAAFILYLIPLIYSFLVLFFGFIEYKQKRTYNLLILCLLYGIVIILICSVGCHGVIKENATSIRSTVVLLIVNNIIMTILITFLLIDILNFPHIVTIHKASKFLQFIVQNKKVGLLFCSLVYLLIFFSFCFMWTVGDYLAHLDAKLCLDDLRISHDIIKSKKKKNSSRNKDTDESEFLIKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYE4</accession>
    <name>A0A1J1GYE4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AP2-coincident C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00515900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530387.1">
        <property type="nucleotide sequence ID" value="XM_028673990.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733692"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00515900"/>
    <dbReference type="OMA" id="KKRWVIK"/>
    <dbReference type="OrthoDB" id="383427at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028078">
        <property type="entry name" value="ACDC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14733">
        <property type="entry name" value="ACDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP2-coincident C-terminal" evidence="2">
        <location>
            <begin position="1574"/>
            <end position="1663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="970"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1427"/>
            <end position="1470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="989"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1427"/>
            <end position="1462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1666" mass="197011" checksum="6D1C86232ECD1CB7" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYK7</accession>
    <name>A0A1J1GYK7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Plasmodium RESA N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00497400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000099">
        <property type="protein sequence ID" value="CRG97399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530201.1">
        <property type="nucleotide sequence ID" value="XM_028673783.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYK7"/>
    <dbReference type="GeneID" id="39733507"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00497400"/>
    <dbReference type="OMA" id="FHINKDE"/>
    <dbReference type="OrthoDB" id="5150177at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.180">
        <property type="entry name" value="Plasmodium RESA, N-terminal helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006526">
        <property type="entry name" value="Export_prot_PHISTa/b/c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019111">
        <property type="entry name" value="PRESA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044885">
        <property type="entry name" value="PRESA_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01639">
        <property type="entry name" value="P_fal_TIGR01639"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36193">
        <property type="entry name" value="PHISTB DOMAIN-CONTAINING RESA-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36193:SF23">
        <property type="entry name" value="PHISTB DOMAIN-CONTAINING RESA-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09687">
        <property type="entry name" value="PRESAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="Plasmodium RESA N-terminal" evidence="3">
        <location>
            <begin position="196"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="335" mass="40346" checksum="4419FBB7B44383DB" modified="2017-02-15" version="1">MRLTNTINFILPQRFLVSNNASISNLDISSFNGEKKNFQKRIFSNFLFSRLFILYFFSFLYLFLLNICVSKDNAFSGLELNKVYDRKLAEHIRKRGEDSEQQKTNFHINKDEKSHSNYASSVRSEQNQSDKQNHEKKSDLKKKEILEESDRIEKKNDKVHDKMDKRKMNDEMGKQEIQNEGCAISLGNRSSELHYQLSENEINERIKNLGDIPSLQDIYILWWQVRGDQRRNFLVIGYYLEKLFKSLMKTHKFDQRFLKKEWNKWYHGLLNDLIAMETKDNKNFYSLLKKESWTREKFEDFIDTNILEWKNHKINTRKKWESTLTEDFNKKKNDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYP3</accession>
    <name>A0A1J1GYP3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00514900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530377.1">
        <property type="nucleotide sequence ID" value="XM_028673979.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYP3"/>
    <dbReference type="GeneID" id="39733682"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00514900"/>
    <dbReference type="OrthoDB" id="370030at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="43"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="521" mass="62402" checksum="FD70B45D2CF40BCC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYS5</accession>
    <name>A0A1J1GYS5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00338100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528968.1">
        <property type="nucleotide sequence ID" value="XM_028672413.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYS5"/>
    <dbReference type="GeneID" id="39731911"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00338100"/>
    <dbReference type="OMA" id="SWEYVEG"/>
    <dbReference type="OrthoDB" id="187617at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070063">
        <property type="term" value="F:RNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.440">
        <property type="entry name" value="FF domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002713">
        <property type="entry name" value="FF_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036517">
        <property type="entry name" value="FF_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045148">
        <property type="entry name" value="TCRG1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15377">
        <property type="entry name" value="TRANSCRIPTION ELONGATION REGULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15377:SF3">
        <property type="entry name" value="WW DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01846">
        <property type="entry name" value="FF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81698">
        <property type="entry name" value="FF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51676">
        <property type="entry name" value="FF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="WW" evidence="3">
        <location>
            <begin position="39"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="FF" evidence="4">
        <location>
            <begin position="490"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="101"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="103"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="568" mass="69323" checksum="C7DA628D5EA46BE3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYW8</accession>
    <name>A0A1J1GYW8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Small heat shock protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00500500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530234.1">
        <property type="nucleotide sequence ID" value="XM_028673819.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYW8"/>
    <dbReference type="GeneID" id="39733538"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00500500"/>
    <dbReference type="OMA" id="FECMNEQ"/>
    <dbReference type="OrthoDB" id="1431247at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06464">
        <property type="entry name" value="ACD_sHsps-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031107">
        <property type="entry name" value="Small_HSP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11527">
        <property type="entry name" value="HEAT-SHOCK PROTEIN 20 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="SHSP" evidence="4">
        <location>
            <begin position="95"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="207" mass="24666" checksum="3B660E7CC7C89770" modified="2017-02-15" version="1">MVNDDIIKPDSGKDNRSTIANFGMLDNFFENMYEQMNKIDQYHHDMSRMMNSLRECYFGNDYFNKYFPERRSLLDYDFRKNRNTELFFPKPHSIFRGYKNMPPMDVIDKDKEIEIKMDVPGLNKENVQINLCNGRLEISGGSQKTEETKNEEHRYYVKERMESSFYRSFTLPENVCEDNIKATFKDGVLKIGIPKKEISEKKKIEIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYW9</accession>
    <name>A0A1J1GYW9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="5">PPIase</shortName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00342900</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cyclophilin-type PPIase family. PPIL3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529016.1">
        <property type="nucleotide sequence ID" value="XM_028672467.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYW9"/>
    <dbReference type="GeneID" id="39731959"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00342900"/>
    <dbReference type="OMA" id="VPFHRVM"/>
    <dbReference type="OrthoDB" id="271386at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01928">
        <property type="entry name" value="Cyclophilin_PPIL3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000012">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF2">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="6">
        <location>
            <begin position="6"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="167" mass="18544" checksum="690C12628C8C700E" modified="2017-02-15" version="1">MSLSLHTNYGDIKIELFCYEVPKTCKNFLALCASGYYDNTKFHRNIKGFAIQGGDPTNTGKGGESIYGKYFEDEFDSTLKHDKRGIVSMANKGKPNTNGSQFFITYSRQPHLNGVYPVFGKVIDGMDVLSVLENEPVGEKNRPIKDIVIESVTIHANPIAEDEAISN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ15</accession>
    <name>A0A1J1GZ15_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycerol-3-phosphate acyltransferase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00527200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530497.1">
        <property type="nucleotide sequence ID" value="XM_028674112.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ15"/>
    <dbReference type="GeneID" id="39733805"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00527200"/>
    <dbReference type="OMA" id="IMALGCM"/>
    <dbReference type="OrthoDB" id="2427554at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004366">
        <property type="term" value="F:glycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016287">
        <property type="term" value="F:glycerone-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07992">
        <property type="entry name" value="LPLAT_AAK14816-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052744">
        <property type="entry name" value="GPAT/DAPAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31605">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31605:SF0">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="380"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="432"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="461"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="2">
        <location>
            <begin position="37"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="583" mass="66949" checksum="2347095B1815BFA8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ19</accession>
    <name>A0A1J1GZ19_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00528600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530510.1">
        <property type="nucleotide sequence ID" value="XM_028674126.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ19"/>
    <dbReference type="GeneID" id="39733819"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00528600"/>
    <dbReference type="OMA" id="YRYECAY"/>
    <dbReference type="OrthoDB" id="368364at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="142" mass="17284" checksum="3A0B9EE6014A6EAA" modified="2017-02-15" version="1">MFKYDKIKKGWRELSRTAKVVYGCFFFNMILLMGITTRRHLANKKAVDFYTNKILDSNNENEDWHCYNVAKQYRYECAYLNEEEMEQLQLCKKLDLKLENCRNKLYDYIKEDTPAMKNIPHIINKPIWLKDPVWFQNLQNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ75</accession>
    <name>A0A1J1GZ75_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pinin/SDK/MemA protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00511000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530338.1">
        <property type="nucleotide sequence ID" value="XM_028673935.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ75"/>
    <dbReference type="GeneID" id="39733643"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00511000"/>
    <dbReference type="OrthoDB" id="330772at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053330">
        <property type="entry name" value="Mucin-22-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006786">
        <property type="entry name" value="Pinin_SDK_MemA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37000">
        <property type="entry name" value="MUCIN-22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37000:SF3">
        <property type="entry name" value="MUCIN-22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04696">
        <property type="entry name" value="Pinin_SDK_memA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pinin/SDK/MemA protein" evidence="3">
        <location>
            <begin position="83"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="250"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="326"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="102"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="334"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="419" mass="50182" checksum="E4FF561A1ABDD12F" modified="2017-02-15" version="1">MKSYLLEEDKLKASIKKCYFERDIIKSKIVNYLNRLTYLSSDERDDNKYKTKQKRIDSSEFLDNLPDFKIEKRPKLEEDESTLTRNKRLLQIGLFDHLKKAKDALEQEKNNKTVILQHLQNKRVEEKILEEKKNFEKSELEDMEKKITTYIKDLKRIEKNIKHDEGKLMKLNLINHYDKMKNFISTNTYPTIFWCPLKFNEKTKILQKNTENFIKKKISAIKSTNYEVNFKEENWLEQFLELKKKVEKKNKTSDNEFKNNNENEKEKNDINENENNKECKNENSFTEEVKQNIDGNSNKEYELNNDKKEKNSFEDEYVTKVIDNDYCNTNTKENSNEKVGKNLKKNSHEEINKREKEDSNENLKENLKNTVEDNSNEDLKENLKNTVEDNSNEDLKENPKNTVKEDSYEDVIENIEKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ78</accession>
    <name>A0A1J1GZ78_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00033700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530699.1">
        <property type="nucleotide sequence ID" value="XM_028674336.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ78"/>
    <dbReference type="GeneID" id="39728860"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00033700"/>
    <dbReference type="OMA" id="ICKRCYM"/>
    <dbReference type="OrthoDB" id="392460at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="230" mass="27778" checksum="26E9F28CEC7C8192" modified="2017-02-15" version="1">MEKLTYLNEYTRIFEFVKNGALFEDQHTEKIDNSCSYKEKNFSHVKRKSKYISMSKLKEKNSSKKLNFYKDNENKYQVSKIKNIDKYLLLSATTTPNLTPKNKNKLDNLKNEMKFYKLTTSNDRMKCHNKVCVCKRCYIKGIQEEIEKREEKKKRTTVYTLEFNNFINKENIYEDISKRQKITKPNSVNERKYSDEYNRECNEVIVEKLTDQIPLKKNIFHFLNYIFKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZB5</accession>
    <name>A0A1J1GZB5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">40S ribosomal protein S11, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00037700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the universal ribosomal protein uS11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530739.1">
        <property type="nucleotide sequence ID" value="XM_028674380.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZB5"/>
    <dbReference type="GeneID" id="39728901"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00037700"/>
    <dbReference type="OMA" id="KWGVAHI"/>
    <dbReference type="OrthoDB" id="1677536at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.80:FF:000002">
        <property type="entry name" value="40S ribosomal protein S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.80">
        <property type="entry name" value="Ribosomal protein S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01310">
        <property type="entry name" value="Ribosomal_uS11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001971">
        <property type="entry name" value="Ribosomal_uS11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018102">
        <property type="entry name" value="Ribosomal_uS11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036967">
        <property type="entry name" value="Ribosomal_uS11_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007176">
        <property type="entry name" value="PRK09607.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11759">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S14/30S RIBOSOMAL PROTEIN S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00411">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002131">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53137">
        <property type="entry name" value="Translational machinery components"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00054">
        <property type="entry name" value="RIBOSOMAL_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="142"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="151" mass="16051" checksum="5DD5E1F80E8E4059" modified="2017-02-15" version="1">MATKKVKTPQPETAVVSGPQAKEGELVFGVAHIFASFNDTFIHVTDLSGRETLVRITGGMKVKADRDESSPYAAMMAAQDVAARLKELGVTAIHIKLRASGGTKSKTPGPGAQSALRALARSGLKIGRIEDVTPIPTDSTRKKSGRRGRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZE4</accession>
    <name>A0A1J1GZE4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00377300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000130">
        <property type="protein sequence ID" value="CRG97972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530771.1">
        <property type="nucleotide sequence ID" value="XM_028674415.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZE4"/>
    <dbReference type="GeneID" id="39732303"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00377300"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="170" mass="20230" checksum="132BF4EED23B2425" modified="2017-02-15" version="1">MSINQTIALCESLDIYYIDNKLSFSSYDVINEKNDLPLKHLKNPNHKIIKSKYKDLFIKEHSCHHIKTKYISHHSCMYAICEKKNEDYMLCSDANYSGKLIFLHDWNPINRKFIYLPESCLKIDSNFVCNTYFCEINAKDEFFPCEYKEISFFFFFFFFFISSLNSSSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZE5</accession>
    <name>A0A1J1GZE5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00517400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530402.1">
        <property type="nucleotide sequence ID" value="XM_028674006.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733707"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00517400"/>
    <dbReference type="OMA" id="YEAKFQF"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000123">
        <property type="term" value="C:histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010484">
        <property type="term" value="F:histone H3 acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037800">
        <property type="entry name" value="GCN5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45750">
        <property type="entry name" value="GH11602P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45750:SF3">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="1207"/>
            <end position="1558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="606"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="999"/>
            <end position="1114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1615"/>
            <end position="1661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="608"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="627"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="644"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="941"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="999"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1034"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1083"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1100"/>
            <end position="1114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1615"/>
            <end position="1625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1627"/>
            <end position="1644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1645"/>
            <end position="1654"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2676" mass="315774" checksum="CB23CB5AEEBC526B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZH8</accession>
    <name>A0A1J1GZH8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Apicoplast ribosomal protein S14p/S29e, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00365200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529232.1">
        <property type="nucleotide sequence ID" value="XM_028672706.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZH8"/>
    <dbReference type="GeneID" id="39732182"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00365200"/>
    <dbReference type="OMA" id="CPVRFRN"/>
    <dbReference type="OrthoDB" id="413436at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.1480:FF:000001">
        <property type="entry name" value="30S ribosomal protein S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001209">
        <property type="entry name" value="Ribosomal_uS14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018271">
        <property type="entry name" value="Ribosomal_uS14_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006477">
        <property type="entry name" value="PRK08881.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19836">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19836:SF19">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US14M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00253">
        <property type="entry name" value="Ribosomal_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00527">
        <property type="entry name" value="RIBOSOMAL_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009618949" evidence="4">
        <location>
            <begin position="18"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="168" mass="20670" checksum="DCB38BB5CC540132" modified="2017-02-15" version="1">MLNFIKYFLAYLILVDTQFFCINHQYSFQFFINNYKIYKNGRSKNYLKRIIHLNLKKRLDPSNKYTVIKRHEAKIQRNLKRKYLIERYKEKRDLLKKYISEASSPIEYVYWKYKLSRLPRDSCPVRYRNRCAITGRARGYYKFFGLCRHQARALIQKMFFPGFVKASW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZL2</accession>
    <name>A0A1J1GZL2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Purine nucleoside phosphorylase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PNP</name>
        <name evidence="2" type="ORF">PGAL8A_00034700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530710.1">
        <property type="nucleotide sequence ID" value="XM_028674348.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZL2"/>
    <dbReference type="GeneID" id="39728871"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00034700"/>
    <dbReference type="OMA" id="PQCLLCG"/>
    <dbReference type="OrthoDB" id="416752at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004850">
        <property type="term" value="F:uridine phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006218">
        <property type="term" value="P:uridine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17767">
        <property type="entry name" value="UP_EcUdp-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="entry name" value="Nucleoside phosphorylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43691:SF11">
        <property type="entry name" value="FI09636P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43691">
        <property type="entry name" value="URIDINE PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="Purine and uridine phosphorylases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleoside phosphorylase" evidence="1">
        <location>
            <begin position="18"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="245" mass="27280" checksum="7C340D3BB6D9D744" modified="2017-02-15" version="1">MTDTQRHIKLTEKQTTPVILVVGDPGRVDKVKLLCDSYVDLTYNREYKSVECHYKGQKFLCVSHGVGSSGCAICFEELIQNGAKVIIRAGSCGTLQPQEMKRGDICICNAAVREDRVSHLLVHADFPAVGDFEVYETLNKCAEELNEHVFNGISLSTDLYYPNKIIPSRLEDYAKANVAVVEMEVATLMVIGSLRKIKTGGIFIVDGCPLKWDEGDFDNNLIPEKLEKMIKISLEACARLAAKYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZW4</accession>
    <name>A0A1J1GZW4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Rhoptry-associated protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00055500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530917.1">
        <property type="nucleotide sequence ID" value="XM_028674579.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZW4"/>
    <dbReference type="GeneID" id="39729080"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00055500"/>
    <dbReference type="OrthoDB" id="386690at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012768905" description="Rhoptry-associated protein 1" evidence="2">
        <location>
            <begin position="19"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="94"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="595" mass="70562" checksum="8E845A830A2F61FD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H057</accession>
    <name>A0A1J1H057_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lysine decarboxylase, putative</fullName>
            <ecNumber evidence="3">4.1.1.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00056400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.18" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530926.1">
        <property type="nucleotide sequence ID" value="XM_028674589.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729089"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00056400"/>
    <dbReference type="OMA" id="INCSSFE"/>
    <dbReference type="OrthoDB" id="5978656at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008792">
        <property type="term" value="F:arginine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008923">
        <property type="term" value="F:lysine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006527">
        <property type="term" value="P:L-arginine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00615">
        <property type="entry name" value="Orn_deC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.105.10">
        <property type="entry name" value="Molybdopterin biosynthesis moea protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011193">
        <property type="entry name" value="Orn/lys/arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000310">
        <property type="entry name" value="Orn/Lys/Arg_deCO2ase_major_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036633">
        <property type="entry name" value="Prn/Lys/Arg_de-COase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45229:SF3">
        <property type="entry name" value="BIODEGRADATIVE ARGININE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45229">
        <property type="entry name" value="CONSTITUTIVE ORNITHINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01276">
        <property type="entry name" value="OKR_DC_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55904">
        <property type="entry name" value="Ornithine decarboxylase C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site" evidence="2">
        <location>
            <begin position="418"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="domain" description="Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site" evidence="2">
        <location>
            <begin position="695"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="891"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="891"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="910"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="922"/>
            <end position="932"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1990" mass="231044" checksum="4AACC66E87EB845A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H076</accession>
    <name>A0A1J1H076_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00028500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530650.1">
        <property type="nucleotide sequence ID" value="XM_028674281.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H076"/>
    <dbReference type="GeneID" id="39728808"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00028500"/>
    <dbReference type="OMA" id="VCIEFDQ"/>
    <dbReference type="OrthoDB" id="383171at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="155" mass="18350" checksum="0239B7FE6E60B71A" modified="2017-02-15" version="1">MNFTLCILFIFSVYFFFFINKFSGANFTSVKPIFNKIMIEENNWKNNKDNNVCSNKLILKIIRSEIGYNEFPSKSLLMTSRLNNIKRLFDDFSKDKNLSKMIEDCGNYVYLKYVKTIIFNLNENVQILNLKKFLQLLINKDVCIEFNSDVVQFVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0H5</accession>
    <name>A0A1J1H0H5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00050200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530864.1">
        <property type="nucleotide sequence ID" value="XM_028674519.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729027"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00050200"/>
    <dbReference type="OMA" id="NKWKNYC"/>
    <dbReference type="OrthoDB" id="377698at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG98067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2973" mass="371626" checksum="CEC4BFBFD5DD0EA9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0L3</accession>
    <name>A0A1J1H0L3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Double C2-like domain-containing protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">DOC2</name>
        <name evidence="4" type="ORF">PGAL8A_00464600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529869.1">
        <property type="nucleotide sequence ID" value="XM_028673414.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733179"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00464600"/>
    <dbReference type="OMA" id="NIWYDYW"/>
    <dbReference type="OrthoDB" id="67700at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052299">
        <property type="entry name" value="CEP76"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056288">
        <property type="entry name" value="CEP76_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056290">
        <property type="entry name" value="CEPT76/DRC7_peptidase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46436">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 76 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46436:SF2">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_119, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24652">
        <property type="entry name" value="CEP76_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24656">
        <property type="entry name" value="CEPT76_peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="3">
        <location>
            <begin position="496"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="16"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="303"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1199"/>
            <end position="1283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1340"/>
            <end position="1370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1478"/>
            <end position="1581"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1128"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="314"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1199"/>
            <end position="1223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1268"/>
            <end position="1283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1340"/>
            <end position="1360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1361"/>
            <end position="1370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1716" mass="204368" checksum="E1ED6F31A7F22665" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0S4</accession>
    <name>A0A1J1H0S4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00445800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529680.1">
        <property type="nucleotide sequence ID" value="XM_028673204.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0S4"/>
    <dbReference type="GeneID" id="39732991"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00445800"/>
    <dbReference type="OMA" id="WGININI"/>
    <dbReference type="OrthoDB" id="386230at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="572"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1006" mass="122898" checksum="31B55FBDE76743F0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0S8</accession>
    <name>A0A1J1H0S8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Inner membrane complex protein 1d, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">IMC1d</name>
        <name evidence="2" type="ORF">PGAL8A_00048800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530850.1">
        <property type="nucleotide sequence ID" value="XM_028674504.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0S8"/>
    <dbReference type="GeneID" id="39729013"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00048800"/>
    <dbReference type="OMA" id="VIYVDCC"/>
    <dbReference type="OrthoDB" id="377318at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="76"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="255" mass="29897" checksum="FCA1BF08AA916BB0" modified="2017-02-15" version="1">MELIQESNKNINDNENIEINGSDNFINQENELHVSVIKPITKKIIHCTNTKINAFYKPVELVEEVNSYVKKGDEYLVNLYEDLKKLENEKEAELKNKNTNLRKIKFRNIFNSKNPNKKNPNKKNQFKLFKEDESIIPKIETVFVPKLEKNIEVVSNLKENINVDYTYLVPKPIVIPVEVPILKFKDHFKIVPIKKKIIPVIKYSDDIIYVDCCVEKPYIILENVIVPVPFDIPIEENKYIHKAPPILDNDYSNKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0W6</accession>
    <name>A0A1J1H0W6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioredoxin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00065000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028531008.1">
        <property type="nucleotide sequence ID" value="XM_028674680.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0W6"/>
    <dbReference type="GeneID" id="39729175"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00065000"/>
    <dbReference type="OMA" id="QEVDFMG"/>
    <dbReference type="OrthoDB" id="390285at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="212"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="430" mass="51219" checksum="89D1EA2573FD00F6" modified="2017-02-15" version="1">MNKILNSYKSKLIFPMSKRNFYNFNCIFKIKNGIPIKKNEKINFSKHLQKNIVSYIDFRNKIPNKRRKIYLFSSLITCIIGYKIYKWNESREVTDFLNDMKEISDEIFDNVDNIVLFVLDKNKLSEQKTKIQEIKDEIQKLNIKNINFLYTYNEESKDYACYLYKGRRRRNLTKEELTSNSIKNILTDFFTPVSENYQKINQGNNDNFPTFVTHDTFEKEIIEDSKNNEIILVLFENTCFLCFLYKPFINTLHKLFKDNNIQVKIKKYNVEKNDYAPNMIVCRGTPTFLYYHNGKGNKLVEYKPNDIINKIDEIIKPPKNIKEQMIAKAELIHERMHHFGHLTLWMTESKIIENMLIKRHIKDISNSNDDESLYNEILTSLIEEDMQRNDLIEDSLNYTKGKIKEAEKSCFVVAMMMAQELIDEEKKSMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H193</accession>
    <name>A0A1J1H193_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00464100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529864.1">
        <property type="nucleotide sequence ID" value="XM_028673408.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H193"/>
    <dbReference type="GeneID" id="39733174"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00464100"/>
    <dbReference type="OMA" id="MANTPNE"/>
    <dbReference type="OrthoDB" id="377983at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022086">
        <property type="entry name" value="IMCp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12314">
        <property type="entry name" value="IMCp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="643" mass="77836" checksum="BCA5DBA18AA75F7E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H286</accession>
    <name>A0A1J1H286_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00501900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530247.1">
        <property type="nucleotide sequence ID" value="XM_028673834.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H286"/>
    <dbReference type="GeneID" id="39733552"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00501900"/>
    <dbReference type="OrthoDB" id="378637at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="279" mass="33535" checksum="A2B3563D807C414D" modified="2017-02-15" version="1">MSSIEEQIKNIENKINVQEKKIKNLGEEIGELKNESSTIYEKLIRQKDVLLKKKETNILMEFKINNLKYESIKVTKSIEDTYFKIDSYFKELKRKKFEIKENIKRMEEINNIIKKNIFNDINIDRTFLILEDFLLKKKEHNNYLESFLKKKKEKIERVINEIKKINNNIFFLCQNITVLDNKLITNLYSIKNYINEEINNYLIKNEKINENSIFVTCLSIITKIIEKQKLKNEIVHINFNVNNSIQTTKNNNSQKKNREAKLELELNTQEFLEFENFFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H344</accession>
    <name>A0A1J1H344_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Formin 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00533600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530559.1">
        <property type="nucleotide sequence ID" value="XM_028674180.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733869"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00533600"/>
    <dbReference type="OrthoDB" id="1668162at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2220">
        <property type="entry name" value="Formin, FH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015425">
        <property type="entry name" value="FH2_Formin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042201">
        <property type="entry name" value="FH2_Formin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051425">
        <property type="entry name" value="Formin_Homology"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014020">
        <property type="entry name" value="Tensin_C2-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45725:SF1">
        <property type="entry name" value="DISHEVELLED ASSOCIATED ACTIVATOR OF MORPHOGENESIS, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45725">
        <property type="entry name" value="FORMIN HOMOLOGY 2 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02181">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00498">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01326">
        <property type="entry name" value="PTEN_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101447">
        <property type="entry name" value="Formin homology 2 domain (FH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51182">
        <property type="entry name" value="C2_TENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51444">
        <property type="entry name" value="FH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2 tensin-type" evidence="3">
        <location>
            <begin position="967"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="domain" description="FH2" evidence="4">
        <location>
            <begin position="1913"/>
            <end position="2317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="805"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="939"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1718"/>
            <end position="1810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="812"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="939"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="949"/>
            <end position="959"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2546" mass="300234" checksum="3E30AD4EA87509A4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H426</accession>
    <name>A0A1J1H426_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00054100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530903.1">
        <property type="nucleotide sequence ID" value="XM_028674563.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H426"/>
    <dbReference type="GeneID" id="39729066"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00054100"/>
    <dbReference type="OMA" id="KNKFMYL"/>
    <dbReference type="OrthoDB" id="382546at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="951" mass="115284" checksum="17FB65180B0BDB8E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H499</accession>
    <name>A0A1J1H499_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Actin-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ALP5b</name>
        <name evidence="3" type="ORF">PGAL8A_00060500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530967.1">
        <property type="nucleotide sequence ID" value="XM_028674634.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H499"/>
    <dbReference type="GeneID" id="39729130"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00060500"/>
    <dbReference type="OrthoDB" id="337660at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="410" mass="47789" checksum="C7ABCD201B629688" modified="2017-02-15" version="1">MEYEEEESIPIIILDPGSWIIKIGFANDDLPKFQIPCLYIEKTFVNSRIIKFGNEAIEDYILIKYANSTVGKKEKTSDNNKDDKLLNVKMIFADPRHPLSKNSFTDLFETYNYLLNKLNIKTNDYNLLVVIPETIEKLFISNLLNWAFKNHNFLSISLIFNALAASYYYGLNTGEYGSRIVPVAENHGIFFDSMRNCEIGGYLISKYISNFVKINDNYIDYILIQNYKELNSYVSLDIDNNIKLATECNGLIKPYKIPYSNFYIDPKAEILSHEIYFQPEFLAHLPGNFYKQNIISLNQMAFESICLCPLDLRKKFLNNIILIGGVSNCTNIRERLHMELMHIIKSKNYSESVKINIKEIRMSDIASYLGCKKYGKVLFYNKKKWIKRNEYFTSSKNQIIQKLLMWANVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-11-11" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A0K1SBY5</accession>
    <name>A0A0K1SBY5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8 9">RH5 interacting protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RIPR</name>
        <name evidence="9" type="ORF">PGAL8A_00392900</name>
    </gene>
    <organism evidence="8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2015" name="Malar. J." volume="14" first="296" last="296">
            <title>De novo assembly and transcriptome analysis of Plasmodium gallinaceum identifies the Rh5 interacting protein (ripr), and reveals a lack of EBL and RH gene family diversification.</title>
            <authorList>
                <person name="Lauron E.J."/>
                <person name="Aw Yeang H.X."/>
                <person name="Taffner S.M."/>
                <person name="Sehgal R.N."/>
            </authorList>
            <dbReference type="PubMed" id="26243218"/>
            <dbReference type="DOI" id="10.1186/s12936-015-0814-0"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="9 10" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="KP164517">
        <property type="protein sequence ID" value="AKV72190.1"/>
        <property type="molecule type" value="mRNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527046.1">
        <property type="nucleotide sequence ID" value="XM_028670278.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A0K1SBY5"/>
    <dbReference type="GeneID" id="39732459"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00392900"/>
    <dbReference type="OMA" id="TSSKAYC"/>
    <dbReference type="OrthoDB" id="4405280at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.90.20.10">
        <property type="entry name" value="Plasmodium vivax P25 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24038:SF11">
        <property type="entry name" value="INTEGRIN BETA-LIKE PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24038">
        <property type="entry name" value="STABILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011354997" evidence="6">
        <location>
            <begin position="20"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="7">
        <location>
            <begin position="822"/>
            <end position="860"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AKV72190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1016" mass="116777" checksum="E7CBD02528F6FD21" modified="2015-11-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKU3</accession>
    <name>A0A1J1GKU3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Multidrug resistance protein 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">MDR1</name>
        <name evidence="12" type="ORF">PGAL8A_00070200</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG92998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525820.1">
        <property type="nucleotide sequence ID" value="XM_028673754.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729227"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00070200"/>
    <dbReference type="OMA" id="IGMAAPY"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18577">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF27">
        <property type="entry name" value="ATP-DEPENDENT TRANSLOCASE ABCB1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="55"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="93"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="315"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="761"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="802"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="871"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="897"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="997"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="57"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="377"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="762"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="1095"/>
            <end position="1368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="677"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="683"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="698"/>
            <end position="714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG92998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1376" mass="156583" checksum="753F83100463F5BB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL09</accession>
    <name>A0A1J1GL09_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mannose-6-phosphate isomerase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00078000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525900.1">
        <property type="nucleotide sequence ID" value="XM_028670244.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL09"/>
    <dbReference type="GeneID" id="39729305"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00078000"/>
    <dbReference type="OrthoDB" id="6605218at2759"/>
    <dbReference type="UniPathway" id="UPA00126">
        <property type="reaction ID" value="UER00423"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004476">
        <property type="term" value="F:mannose-6-phosphate isomerase activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009298">
        <property type="term" value="P:GDP-mannose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.441.10">
        <property type="entry name" value="Phosphomannose Isomerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016305">
        <property type="entry name" value="Mannose-6-P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046457">
        <property type="entry name" value="PMI_typeI_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10309">
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    </dbReference>
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        <property type="entry name" value="MANNOSE-6-PHOSPHATE ISOMERASE"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF20511">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RmlC-like cupins"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="156"/>
            <end position="244"/>
        </location>
    </feature>
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            <begin position="135"/>
            <end position="163"/>
        </location>
    </feature>
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            <begin position="140"/>
            <end position="152"/>
        </location>
    </feature>
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        <location>
            <begin position="153"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF20511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="770" mass="91202" checksum="8ABB7351D80550CD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL44</accession>
    <name>A0A1J1GL44_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Hsc70-interacting protein, putative</fullName>
        </submittedName>
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        <name evidence="6" type="primary">HIP</name>
        <name evidence="6" type="ORF">PGAL8A_00074800</name>
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    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
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            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
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    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="protein sequence ID" value="CRG93044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_028675112.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL44"/>
    <dbReference type="GeneID" id="39729273"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00074800"/>
    <dbReference type="OMA" id="YEKRRYK"/>
    <dbReference type="OrthoDB" id="533763at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14438">
        <property type="entry name" value="Hip_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Hsc70-interacting protein-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034649">
        <property type="entry name" value="Hip_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041243">
        <property type="entry name" value="STI1/HOP_DP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006636">
        <property type="entry name" value="STI1_HS-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45883">
        <property type="entry name" value="HSC70-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45883:SF2">
        <property type="entry name" value="HSC70-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18253">
        <property type="entry name" value="HipN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17830">
        <property type="entry name" value="STI1-HOP_DP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00727">
        <property type="entry name" value="STI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="STI1" evidence="5">
        <location>
            <begin position="368"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="44"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="240"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="103"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
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            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
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            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="291"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SMART" id="SM00727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="428" mass="47986" checksum="128B25163E94CB95" modified="2017-02-15" version="1">MLDDKKIEELKEFVSFCEQDPSILLKPELSFFKEFIESFGGKVSNNKDFYEKVPSDESTEEKSDDDEKEDTEEEEEEENCPDLMEEESIECPPLAPNVEEEFSEEKIEEINNLKIEASKLVQENKLEEALEKYNKIISYGNPSAMIYTKRASVLLGLKRPKACIRDCTEALNLNVDSANAYKTRAKAYRYLGKWESAHADIEQGQKIDYDEELWEMQKLIEEKYKKIYEKRRYKINKEEEKKRRKREKELKKRLAAKEAAEKAYKENSKRENYDSDSSDSSYSQPDFSGDFPGGMPGGMPGGMPGGMPGGMPGGMPGGFPGGFPGGFPGGMPGGMPGGMPGGMPGGMPGGMPGGMPGGMPGGMPDLNSPEMKELFNNPQFFQMMQSMMSNPQLLSKYANDPKYKALFENFKNSDFEKMMGKSSPNGKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL77</accession>
    <name>A0A1J1GL77_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Vacuolar protein sorting-associated protein 9, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00086400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525982.1">
        <property type="nucleotide sequence ID" value="XM_028671155.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729388"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00086400"/>
    <dbReference type="OMA" id="PSQINEM"/>
    <dbReference type="OrthoDB" id="300289at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030139">
        <property type="term" value="C:endocytic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.80">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041545">
        <property type="entry name" value="DUF5601"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003123">
        <property type="entry name" value="VPS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045046">
        <property type="entry name" value="Vps9-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037191">
        <property type="entry name" value="VPS9_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23101:SF25">
        <property type="entry name" value="GTPASE-ACTIVATING PROTEIN AND VPS9 DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23101">
        <property type="entry name" value="RAB GDP/GTP EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18151">
        <property type="entry name" value="DUF5601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02204">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00167">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109993">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51205">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VPS9" evidence="3">
        <location>
            <begin position="1099"/>
            <end position="1368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="232"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="351"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="447"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="532"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="836"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1222"/>
            <end position="1245"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1387"/>
            <end position="1437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="351"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="573"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="836"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1229"/>
            <end position="1245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1477" mass="173742" checksum="078691AB770CED17" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLB2</accession>
    <name>A0A1J1GLB2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00069300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG92989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525811.1">
        <property type="nucleotide sequence ID" value="XM_028672754.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLB2"/>
    <dbReference type="GeneID" id="39729218"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00069300"/>
    <dbReference type="OrthoDB" id="371357at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="261"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG92989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="712" mass="83684" checksum="0AFD82F551F95951" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLK0</accession>
    <name>A0A1J1GLK0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00101000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526126.1">
        <property type="nucleotide sequence ID" value="XM_028672755.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLK0"/>
    <dbReference type="GeneID" id="39729535"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00101000"/>
    <dbReference type="OMA" id="WWQASEI"/>
    <dbReference type="OrthoDB" id="363957at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="142" mass="17239" checksum="E22DBD11C9FFD1F0" modified="2017-02-15" version="1">MNSSKKRNNELLFPVAKLQKHFPLIEWWQGKEILHKIQKKNQKNFEKNPCDSLWGKFINCLRKYPHTFSKCKIDAVRYLQCLSSINQKEETDKPMNYVKVLEYFKIFNETSRFKYKKPELQDYSVFQSLSFQKDKDKDKDIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLN6</accession>
    <name>A0A1J1GLN6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transcription factor with AP2 domain(S), putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ApiAP2</name>
        <name evidence="9" type="ORF">PGAL8A_00093900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526057.1">
        <property type="nucleotide sequence ID" value="XM_028671988.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729463"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00093900"/>
    <dbReference type="OrthoDB" id="348021at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00847">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="8">
        <location>
            <begin position="1591"/>
            <end position="1640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="637"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1009"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1532"/>
            <end position="1569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1916"/>
            <end position="1940"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2109"/>
            <end position="2149"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1769"/>
            <end position="1796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1549"/>
            <end position="1560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1916"/>
            <end position="1925"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="2109"/>
            <end position="2132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="2138"/>
            <end position="2147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2633" mass="310891" checksum="F1810404AFCF8B14" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLQ7</accession>
    <name>A0A1J1GLQ7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosphopantothenoylcysteine decarboxylase, putative</fullName>
            <ecNumber evidence="4">4.1.1.36</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00086100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the HFCD (homooligomeric flavin containing Cys decarboxylase) superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.36" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525979.1">
        <property type="nucleotide sequence ID" value="XM_028671122.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLQ7"/>
    <dbReference type="GeneID" id="39729385"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00086100"/>
    <dbReference type="OMA" id="KGLACGD"/>
    <dbReference type="OrthoDB" id="1532798at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071513">
        <property type="term" value="C:phosphopantothenoylcysteine decarboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004633">
        <property type="term" value="F:phosphopantothenoylcysteine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1950">
        <property type="entry name" value="Flavin prenyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036551">
        <property type="entry name" value="Flavin_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003382">
        <property type="entry name" value="Flavoprotein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14359">
        <property type="entry name" value="HOMO-OLIGOMERIC FLAVIN CONTAINING CYS DECARBOXYLASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14359:SF6">
        <property type="entry name" value="PHOSPHOPANTOTHENOYLCYSTEINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02441">
        <property type="entry name" value="Flavoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52507">
        <property type="entry name" value="Homo-oligomeric flavin-containing Cys decarboxylases, HFCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavoprotein" evidence="3">
        <location>
            <begin position="1"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="182" mass="20923" checksum="7AC42DB6BE1EBB91" modified="2017-02-15" version="1">MKILFGISGSIAAIKVNEIIEKLQEHCKTNNISIEIKYVATNIAYEKFLKPFKEKVFLDEDEWLWQKKGDAILHVELRKWADIFIICPLDANTLANISNGICSNLLTCICRCWDFKKTFLVFPCMNTYMYNHPITKEHIDIVSSWGIKVINPIEKLLACGDYGIGALPNIEDVINEIIKYLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLT8</accession>
    <name>A0A1J1GLT8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein L15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00089300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526011.1">
        <property type="nucleotide sequence ID" value="XM_028671477.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLT8"/>
    <dbReference type="GeneID" id="39729417"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00089300"/>
    <dbReference type="OMA" id="HRICVRR"/>
    <dbReference type="OrthoDB" id="10255148at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1120.10:FF:000001">
        <property type="entry name" value="Ribosomal protein L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1120.10">
        <property type="entry name" value="Ribosomal protein l15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024794">
        <property type="entry name" value="Rbsml_eL15_core_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000439">
        <property type="entry name" value="Ribosomal_eL15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020925">
        <property type="entry name" value="Ribosomal_eL15_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_uL23/eL15/eS24_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003269">
        <property type="entry name" value="PRK04243.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11847:SF4">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11847">
        <property type="entry name" value="RIBOSOMAL PROTEIN L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00827">
        <property type="entry name" value="Ribosomal_L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01384">
        <property type="entry name" value="Ribosomal_L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="Ribosomal proteins S24e, L23 and L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01194">
        <property type="entry name" value="RIBOSOMAL_L15E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="205" mass="24137" checksum="27ADBD06AD09A4DD" modified="2017-02-15" version="1">MGAYKYIQEIWKKKQSDAMHFLLRIRTWEYRQLPVVHRVSKPSRPDKARRLGYKAIQGFVIYRVRVRRGDRKKRVRKGIVHGKPKHQGVHKQKSARNLRSVAEGKVGKSICGNLRVLNSYWVGQDAVYKYYEVILVDPMHNAIRNNPKVNWICNSVHKHRELRGLTSAGKKYRGLRVKGHLAAKSRPSIRANWKRRQLIKLKKCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GME7</accession>
    <name>A0A1J1GME7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SAC3/GANP/THP3 conserved domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00131100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526428.1">
        <property type="nucleotide sequence ID" value="XM_028674837.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729836"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00131100"/>
    <dbReference type="OMA" id="HVFYHYL"/>
    <dbReference type="OrthoDB" id="199574at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070390">
        <property type="term" value="C:transcription export complex 2"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045107">
        <property type="entry name" value="SAC3/GANP/THP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005062">
        <property type="entry name" value="SAC3/GANP/THP3_conserved"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12436">
        <property type="entry name" value="80 KDA MCM3-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12436:SF3">
        <property type="entry name" value="GERMINAL-CENTER ASSOCIATED NUCLEAR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03399">
        <property type="entry name" value="SAC3_GANP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAC3/GANP/THP3 conserved" evidence="2">
        <location>
            <begin position="1096"/>
            <end position="1381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="460"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="538"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="562"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1410" mass="168128" checksum="8A29ACA261C92C09" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMJ0</accession>
    <name>A0A1J1GMJ0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cyclin related protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00128700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526402.1">
        <property type="nucleotide sequence ID" value="XM_028674808.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMJ0"/>
    <dbReference type="GeneID" id="39729812"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00128700"/>
    <dbReference type="OMA" id="CESIFCD"/>
    <dbReference type="OrthoDB" id="372481at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="214"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="818" mass="97245" checksum="165F6BD8C967C6D8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMK1</accession>
    <name>A0A1J1GMK1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00118300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526299.1">
        <property type="nucleotide sequence ID" value="XM_028674677.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMK1"/>
    <dbReference type="GeneID" id="39729708"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00118300"/>
    <dbReference type="OMA" id="KEKFYDC"/>
    <dbReference type="OrthoDB" id="369624at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="113"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="185" mass="21608" checksum="3CADE5AE0EAC8AF0" modified="2017-02-15" version="1">MISITLTNDSVHDKISDLGLSVFIGNIKRTKKLLKKNDINSKFMNNNNLLHICSYNEDANMFYFLLTNGCDYKHINDNGDTCLHIIALNNNLYCLDILCRNNIKDIINIKNKEGDTALHISIKNGFYRFFSLLIKYGADTCIKDNFDMDCYELVDLYRKKEKFYDCESNTYSNMYNLLMNIRKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMN2</accession>
    <name>A0A1J1GMN2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00137000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526487.1">
        <property type="nucleotide sequence ID" value="XM_028674903.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMN2"/>
    <dbReference type="GeneID" id="39729895"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00137000"/>
    <dbReference type="OMA" id="MAIVPIC"/>
    <dbReference type="OrthoDB" id="373923at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="101" mass="11991" checksum="20A4A1CBECB871A7" modified="2017-02-15" version="1">MNHIKAIFYKNQTSRNLFFSLNKNVNNQLKRNMSTDKKNLKDYETNVDNVATNLPKGIRIPIMNYLYGIIFLMAFVPICQSLYETNKYYKENKHLYGKEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMR8</accession>
    <name>A0A1J1GMR8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transcription factor with AP2 domain(S), putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ApiAP2</name>
        <name evidence="9" type="ORF">PGAL8A_00142400</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526540.1">
        <property type="nucleotide sequence ID" value="XM_028674961.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729948"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00142400"/>
    <dbReference type="OrthoDB" id="331552at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2050">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00847">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="8">
        <location>
            <begin position="2289"/>
            <end position="2338"/>
        </location>
    </feature>
    <feature type="domain" description="AP2/ERF" evidence="8">
        <location>
            <begin position="2806"/>
            <end position="2855"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1314"/>
            <end position="1374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2227"/>
            <end position="2255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2455"/>
            <end position="2478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2592"/>
            <end position="2611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2985"/>
            <end position="3039"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="736"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1817"/>
            <end position="1858"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1993"/>
            <end position="2020"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1318"/>
            <end position="1344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1355"/>
            <end position="1374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="2240"/>
            <end position="2255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="2455"/>
            <end position="2469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="2985"/>
            <end position="3001"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="3008"/>
            <end position="3029"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="3030"/>
            <end position="3039"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3215" mass="374272" checksum="51A3865B8CBE654D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNA9</accession>
    <name>A0A1J1GNA9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">CUGBP Elav-like family member 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CELF1</name>
        <name evidence="7" type="ORF">PGAL8A_00165900</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526772.1">
        <property type="nucleotide sequence ID" value="XM_028675218.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNA9"/>
    <dbReference type="GeneID" id="39730185"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00165900"/>
    <dbReference type="OMA" id="FPCHPAP"/>
    <dbReference type="OrthoDB" id="267048at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010629">
        <property type="term" value="P:negative regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009967">
        <property type="term" value="P:positive regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd12362">
        <property type="entry name" value="RRM3_CELF1-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000359">
        <property type="entry name" value="CUGBP Elav-like family member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000383">
        <property type="entry name" value="Sex lethal, isoform D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050502">
        <property type="entry name" value="Euk_RNA-bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002343">
        <property type="entry name" value="Hud_Sxl_RNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48025">
        <property type="entry name" value="OS02G0815200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48025:SF1">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00961">
        <property type="entry name" value="HUDSXLRNA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="86"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="185"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="5">
        <location>
            <begin position="318"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="370"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="469"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="51"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="511" mass="57238" checksum="B45405BDE7372C3B" modified="2017-02-15" version="1">MDNNENIDSNDNSSDTNTVNYNNGKSENLSEGNDFAKENNHLNGNAKNSKTKQENANKTKNSSDKDDNNDYNNHKFPCHPAPPVPIKLFIGRIPKNVEEDQLRPIFEEYGIVNEVVIIRDKITNVHKSSAFVKMACIAEADNAIRSLNNQKTLDPQLGSLQVKYASGEVIKLGFPQNIESGVDQAKLFIGSLPKNITEDNIKEMFSPYGSVEEVFIMKDNSTGLGKGCSFVKFSYKEQALYAINSLNGKKTLEGCTRPIEVRFAEPKSAKQPQIPLTLQPMQNSTHGISPQPHINNPNNINYANNFSINNNYPRQIGPWKEYFSGEGRPYYYNEQTNTTQWEMPKEFETLFMNSSPNMHNLSDSSGPPGANLFIFHVPNEWQQADLIQAFSPFGELLSARIATEKNTGRNRGFAFVSYDNIESAAAAISQMNGFMALNKKLKVTVKKGEEEEMKKFVNQNGINSFQQLSHPQKNIPSQPNAAAQPTAPSHQNAQSQNCFYTNNNCYRCGPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNG8</accession>
    <name>A0A1J1GNG8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00170100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG93994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526815.1">
        <property type="nucleotide sequence ID" value="XM_028670021.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNG8"/>
    <dbReference type="GeneID" id="39730228"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00170100"/>
    <dbReference type="OMA" id="YMQRYEQ"/>
    <dbReference type="OrthoDB" id="376102at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="101"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="226" mass="27066" checksum="A87A16B67058E951" modified="2017-02-15" version="1">MRNDEILIRNINILEEVGNNLVEILKNLESILYHLEPLNNYEEKEDDIFANLTEKKNDIILLSNVLYNNIKHVNNVLHDFIKTVSPSYTYYNSFYYNDFLIIKEKKKYEKRENEKESIEDNIKSIEERSLIVKKRSNLNDDKLINNNEIIEGNENAIRINNNLNMIKNDDFLSHIIEENTDTSNKNECKDIEESLYFSFLIDLEYANLLYMKKYEEKIEKYLVEMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNN6</accession>
    <name>A0A1J1GNN6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">U3 snoRNA-associated small subunit rRNA processing, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00164100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526753.1">
        <property type="nucleotide sequence ID" value="XM_028675197.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNN6"/>
    <dbReference type="GeneID" id="39730166"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00164100"/>
    <dbReference type="OMA" id="CIYAWRA"/>
    <dbReference type="OrthoDB" id="10250769at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034388">
        <property type="term" value="C:Pwp2p-containing subcomplex of 90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007319">
        <property type="entry name" value="WDR36/Utp21_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22840">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22840:SF12">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25168">
        <property type="entry name" value="Beta-prop_WDR36-Utp21_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04192">
        <property type="entry name" value="Utp21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WDR36/Utp21 C-terminal" evidence="2">
        <location>
            <begin position="987"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1213" mass="143252" checksum="D271D374E6E41863" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNZ5</accession>
    <name>A0A1J1GNZ5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CWC16 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00391300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527030.1">
        <property type="nucleotide sequence ID" value="XM_028670260.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNZ5"/>
    <dbReference type="GeneID" id="39732443"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00391300"/>
    <dbReference type="OMA" id="MNKRHID"/>
    <dbReference type="OrthoDB" id="674963at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071006">
        <property type="term" value="C:U2-type catalytic step 1 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007590">
        <property type="entry name" value="Saf4/Yju2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111">
        <property type="entry name" value="SPLICING FACTOR YJU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111:SF1">
        <property type="entry name" value="SPLICING FACTOR YJU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04502">
        <property type="entry name" value="Saf4_Yju2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="157"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="270"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="383" mass="45611" checksum="EFF269F0BF54E00B" modified="2017-02-15" version="1">MAERKVLNKYIPPDFDPDKLIESKKLLKKIEKRKNKNKNKNKKKLLNIRMMYPFTLKCNKCNSFTYVGTKFNSRVEKLKDENYLNIPIWKFYGKCQDCKNEIIFKTDPKNGDYLLISGGVRTYDAHKEQELADDFYRSNNNAGEEDKIKNTEKESYNALLELKRNEQLEELQNMNKRHIDKFNSINKALSHLYEKSENENNENKFYMNYLDSEDEKAFFNLLNKNRTFTEDANERINKDQGIISNTYKGENNNLVVEEEMEEEVDEETLKNDLIIKNEEKLQDINEIKKNEEFLKENVHNNLEETKKLNKKNKINNNNIIKFNKDDSEYNDSVNNNHNISNLKNNIFKKKNLETGYNFIIKKKENLSDIFNEYNSDNTDDLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP07</accession>
    <name>A0A1J1GP07_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Mitochondrial import receptor subunit TOM22, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">TOM22</name>
        <name evidence="13" type="ORF">PGAL8A_00071900</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tom22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525837.1">
        <property type="nucleotide sequence ID" value="XM_028674790.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP07"/>
    <dbReference type="GeneID" id="39729244"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00071900"/>
    <dbReference type="OMA" id="FHYDKEC"/>
    <dbReference type="OrthoDB" id="386478at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005683">
        <property type="entry name" value="Tom22"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04281">
        <property type="entry name" value="Tom22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11 13" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG93015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="105" mass="12092" checksum="282683FB2B337735" modified="2017-02-15" version="1">MGFILSKIKRKNEESDILVSKKPTFNFEKKDTVKIKNKLKLAKSRINNFIKKGIKTTSWVVWIAGVSVVVLITPIAFQYEKECQLFEMQAQFFQAQQAANVPQLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP25</accession>
    <name>A0A1J1GP25_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ADP-ribosylation factor GTPase-activating protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00073500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525853.1">
        <property type="nucleotide sequence ID" value="XM_028674967.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP25"/>
    <dbReference type="GeneID" id="39729260"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00073500"/>
    <dbReference type="OMA" id="PQWIHCI"/>
    <dbReference type="OrthoDB" id="73919at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08204">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.150:FF:000009">
        <property type="entry name" value="stromal membrane-associated protein 1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051718">
        <property type="entry name" value="ARF_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45705">
        <property type="entry name" value="FI20236P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45705:SF1">
        <property type="entry name" value="FI20236P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00405">
        <property type="entry name" value="REVINTRACTNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Arf-GAP" evidence="7">
        <location>
            <begin position="12"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="355"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="430" mass="49516" checksum="52EEB4E1F8427C9C" modified="2017-02-15" version="1">MRMANKTNNSHQNEIENITKIKGNNKCADCGAKCPRWASINLGIIICIECSGIHRNLGVHISKVKSLTLDKITPQWIHCIKNIGNDLSNSYYLYNLPKDTYIPKQGDSSVIMQNWIKNKYEKKLYVPANKKEPYQYYLEGMNPKNCLPDDTLANSSSNNESKLPQDKIIDITNFKNENKIETEAGNSGNIDIFDSLKIIENKKTDELISINNNKEKRNFIDNKGNVSSNKIYMNNDFYSFDNMNCDDNKNIGKDSYFFNDIKNSNNSSKLKEFSFNDNNSNVFNEFDNIKSFNNFNDGLNFNKFNEKKNFNNFNDLSEKELRDAKVQAAKKSIAQLFANSKNISFSEKNIANINLNNQDSDNNNLKKNLKKTECNFVNETKQNLFDKTYVNNLNSCNHEEGSFSNNLINEENVNSFKGKNNVLQNFDFFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPC2</accession>
    <name>A0A1J1GPC2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Mitochondrial ribosomal protein L13, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00404900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527166.1">
        <property type="nucleotide sequence ID" value="XM_028670411.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPC2"/>
    <dbReference type="GeneID" id="39732579"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00404900"/>
    <dbReference type="OMA" id="SNVQWKS"/>
    <dbReference type="OrthoDB" id="274622at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_uL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_uL13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023563">
        <property type="entry name" value="Ribosomal_uL13_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_uL13_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545:SF41">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L13, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="RIBOSOMAL PROTEIN L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00783">
        <property type="entry name" value="RIBOSOMAL_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="212" mass="24530" checksum="922EBF18A0C34998" modified="2017-02-15" version="1">MIRKSLLRLAGYPKASFHEQNINPFSNVQWKSSPFLKKNMPKTDIFAEEHISKNAISVFDKEKGNWFVIDATDKSVGSLSVCISRLLQGKYRVDYNSNRVNSSSVIVVNAIHVKFYGHTWDTKIYKFPRKSHSKGHKILTCKTVFARNPSMILNLAVKRMLPNNRLRQIFYRKLFVYPGALHPHWGIPQVIIPKNKINKDNEQNSIKTFTII</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPJ5</accession>
    <name>A0A1J1GPJ5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mago nashi protein homologue, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00181500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mago nashi family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527244.1">
        <property type="nucleotide sequence ID" value="XM_028670497.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPJ5"/>
    <dbReference type="GeneID" id="39730342"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00181500"/>
    <dbReference type="OMA" id="IRKEMWI"/>
    <dbReference type="OrthoDB" id="6495301at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035145">
        <property type="term" value="C:exon-exon junction complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11295">
        <property type="entry name" value="Mago_nashi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1560.10:FF:000001">
        <property type="entry name" value="Protein mago nashi homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1560.10">
        <property type="entry name" value="Mago nashi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004023">
        <property type="entry name" value="Mago_nashi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036605">
        <property type="entry name" value="Mago_nashi_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12638:SF0">
        <property type="entry name" value="MAGO HOMOLOG, EXON JUNCTION COMPLEX SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12638">
        <property type="entry name" value="PROTEIN MAGO NASHI HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02792">
        <property type="entry name" value="Mago_nashi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89817">
        <property type="entry name" value="Mago nashi protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="148" mass="17577" checksum="379DDE2861DC0891" modified="2017-02-15" version="1">MSKKDRFSFRYYVGHEGKFGHEFLEFEFNSKGRLRYANNSNYKNDKIIRKEAYVSKSVLNELKRIIEESEICKESDKLWPVPDKIGKQELEIFLDGNEYYFTTSKIGSLSDVKQCNDPDGLRVFYYLVQDLKCFLFSLICLHFRIKPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPM1</accession>
    <name>A0A1J1GPM1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00395000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527067.1">
        <property type="nucleotide sequence ID" value="XM_028670301.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPM1"/>
    <dbReference type="GeneID" id="39732480"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00395000"/>
    <dbReference type="OMA" id="RIYQIYI"/>
    <dbReference type="OrthoDB" id="378763at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1088"/>
            <end position="1108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="445"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="117"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1109" mass="134659" checksum="1AC0FCD0553D7EE5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPP4</accession>
    <name>A0A1J1GPP4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Eukaryotic translation initiation factor 2 subunit 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Eukaryotic translation initiation factor 2 subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PGAL8A_00096900</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. May regulate protein translation in response to amino acid starvation. May regulate protein at various stages of parasite development.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Stress granule</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eIF-2-alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526085.1">
        <property type="nucleotide sequence ID" value="XM_028672299.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPP4"/>
    <dbReference type="GeneID" id="39729493"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00096900"/>
    <dbReference type="OMA" id="WNNTEAL"/>
    <dbReference type="OrthoDB" id="1685042at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010494">
        <property type="term" value="C:cytoplasmic stress granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005850">
        <property type="term" value="C:eukaryotic translation initiation factor 2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04452">
        <property type="entry name" value="S1_IF2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1130:FF:000003">
        <property type="entry name" value="Eukaryotic translation initiation factor 2 alpha subunit, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000015">
        <property type="entry name" value="Eukaryotic translation initiation factor 2 subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1130">
        <property type="entry name" value="EIF_2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.190">
        <property type="entry name" value="Translation initiation factor 2, subunit 1, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044126">
        <property type="entry name" value="S1_IF2_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024055">
        <property type="entry name" value="TIF2_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024054">
        <property type="entry name" value="TIF2_asu_middle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011488">
        <property type="entry name" value="TIF_2_asu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10602">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10602:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07541">
        <property type="entry name" value="EIF_2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110993">
        <property type="entry name" value="eIF-2-alpha, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116742">
        <property type="entry name" value="eIF2alpha middle domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 14" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="S1 motif" evidence="13">
        <location>
            <begin position="24"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="288"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="288"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="298"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00058648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG93263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="332" mass="38230" checksum="BB19A2919FB61D03" modified="2017-02-15" version="1">MAETRNKVDLGDCRFYEKKFPEVDDLIMVKVNRIEDMGAYVSILEYNDMEGMILMSELSKRRFRSVNKLIRVGRHEVVLVLRVDSQKGYIDLSKRRVSPKDIIKCEEKFSKSKKVHQTVRHVAQKHGMTVEELNRRAIWPLYKKYDHALDALKEATMNPEGVFKGLDIDEEIKKSLLADIQLRLTPQALKLRGRIDVWCFSYEGIDAVKEALKKGKEISNEEVSINIKLIAPPQYVIVTSCHDKELGMAKIQEAMKVISDKIKEYKGGDFKQQGDILVIGGDEEKRLEELLDKHDELSSEEEDDNSSEEDEENSSNEEEDDNSSEEGEDEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ17</accession>
    <name>A0A1J1GQ17_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ferlin, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00108800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526205.1">
        <property type="nucleotide sequence ID" value="XM_028673632.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729614"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00108800"/>
    <dbReference type="OrthoDB" id="270970at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007009">
        <property type="term" value="P:plasma membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04037">
        <property type="entry name" value="C2E_Ferlin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037724">
        <property type="entry name" value="C2E_Ferlin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012968">
        <property type="entry name" value="FerIin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037721">
        <property type="entry name" value="Ferlin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12546">
        <property type="entry name" value="FER-1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12546:SF33">
        <property type="entry name" value="SPERM VESICLE FUSION PROTEIN FER-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM01202">
        <property type="entry name" value="FerI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1551"/>
            <end position="1572"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="157"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="597"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="1346"/>
            <end position="1467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="962"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="962"/>
            <end position="974"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1573" mass="182012" checksum="4725378B09709FF2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ92</accession>
    <name>A0A1J1GQ92_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00206800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527486.1">
        <property type="nucleotide sequence ID" value="XM_028670767.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ92"/>
    <dbReference type="GeneID" id="39730595"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00206800"/>
    <dbReference type="OMA" id="CDCSNPS"/>
    <dbReference type="OrthoDB" id="359487at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013221411" evidence="1">
        <location>
            <begin position="23"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="118" mass="13576" checksum="B2EEC73B4888B11E" modified="2017-02-15" version="1">MERSIFYIFIIFIWIFHSPVNCQICTTDICQRCCYPTEDGCENNFIRTFRGNFNSGSTYCQQCDCKNPITGCGWVAEKYEKIKCTSCTFIKHASLKIKYFDISGCGYHLENGKLVNAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQB5</accession>
    <name>A0A1J1GQB5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Serine/threonine protein kinase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00200500</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527423.1">
        <property type="nucleotide sequence ID" value="XM_028670696.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730531"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00200500"/>
    <dbReference type="OrthoDB" id="193931at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14003">
        <property type="entry name" value="STKc_AMPK-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF82">
        <property type="entry name" value="KP78A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="119"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="469"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1209"/>
            <end position="1230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1245"/>
            <end position="1277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1346"/>
            <end position="1373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="2134"/>
            <end position="2176"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="2189"/>
            <end position="2217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="469"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1249"/>
            <end position="1271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1346"/>
            <end position="1365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="2134"/>
            <end position="2147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="2149"/>
            <end position="2170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG94608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2841" mass="335373" checksum="F4818705EAD3A7C6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQE9</accession>
    <name>A0A1J1GQE9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00216200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0235 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527580.1">
        <property type="nucleotide sequence ID" value="XM_028670871.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQE9"/>
    <dbReference type="GeneID" id="39730689"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00216200"/>
    <dbReference type="OMA" id="CANFMYR"/>
    <dbReference type="OrthoDB" id="244097at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1200.10">
        <property type="entry name" value="YggU-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00634">
        <property type="entry name" value="UPF0235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003746">
        <property type="entry name" value="DUF167"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036591">
        <property type="entry name" value="YggU-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00251">
        <property type="entry name" value="DUF167 family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47817">
        <property type="entry name" value="OS04G0686300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47817:SF2">
        <property type="entry name" value="OS04G0686300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02594">
        <property type="entry name" value="DUF167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01152">
        <property type="entry name" value="DUF167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69786">
        <property type="entry name" value="YggU-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="130" mass="15048" checksum="44D92EC413123860" modified="2017-02-15" version="1">MYKGNILLKHLRKNMSKNMSKETAKNFIETIPNYIKKKNESFLLSLRVKPNSKTTSIYFNSDKEVLNINIQEQPINNQSNLAIINYFSDILQLKKRDISIVSGLKSRDKVLMVSNISLEDLNNKISENIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQN0</accession>
    <name>A0A1J1GQN0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Yos1-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00212500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527543.1">
        <property type="nucleotide sequence ID" value="XM_028670829.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQN0"/>
    <dbReference type="GeneID" id="39730652"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00212500"/>
    <dbReference type="OMA" id="FFTVRTY"/>
    <dbReference type="OrthoDB" id="15356at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013880">
        <property type="entry name" value="Yos1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08571">
        <property type="entry name" value="Yos1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="76" mass="9115" checksum="86DB59D45ABA4641" modified="2017-02-15" version="1">MSMYFFLLFESVVLLINSVLIINEKKLKKYKKIDISLNSNDIFNNIKLLFYTIRIYFKIPLIFLNFLCIIIEILFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR08</accession>
    <name>A0A1J1GR08_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00237200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527788.1">
        <property type="nucleotide sequence ID" value="XM_028671103.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR08"/>
    <dbReference type="GeneID" id="39730900"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00237200"/>
    <dbReference type="OMA" id="NERIHMI"/>
    <dbReference type="OrthoDB" id="392316at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="18"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="134" mass="15914" checksum="1C2831617E644A2F" modified="2017-02-15" version="1">MEENIIEKIEKISLNTINQESYNEKKGLKSKIRDLENIIETKILQLQNQLKESKEKEKVDEYDFSEILNEFKEDIKKKLEETNELIIKKIEEQNIKHLKLFNILVSLKNENSSINKSISLLNERIHMIEEDIGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR20</accession>
    <name>A0A1J1GR20_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome c oxidase assembly protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00118800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PET191 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526304.1">
        <property type="nucleotide sequence ID" value="XM_028674699.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR20"/>
    <dbReference type="GeneID" id="39729713"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00118800"/>
    <dbReference type="OMA" id="SFIDCLH"/>
    <dbReference type="OrthoDB" id="282149at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018793">
        <property type="entry name" value="Cyt_c_oxidase_assmbl_Pet191"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28627">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28627:SF1">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10203">
        <property type="entry name" value="Pet191_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="85" mass="9830" checksum="034E491CFCF6F3F7" modified="2017-02-15" version="1">MLSVKPDTPHRKASNSCKKILNDMIACYQNTICYKKENSSFIDCLHNHNLDEIDENCIILRKAYAQCRRNLLNGNFKMLGNPLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR29</accession>
    <name>A0A1J1GR29_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00212100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527539.1">
        <property type="nucleotide sequence ID" value="XM_028670825.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR29"/>
    <dbReference type="GeneID" id="39730648"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00212100"/>
    <dbReference type="OMA" id="THCKKIN"/>
    <dbReference type="OrthoDB" id="364491at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="227" mass="27900" checksum="50E59049558B3A7F" modified="2017-02-15" version="1">MTLIRRVKKNVLHTFKEIYKKGKSLNIHKTTFLCQTYEKNCWRKTRVREEKVYYKKYNFLKHAYDVINYGVDNNLKFEIDEKNIDEESSYITEEIKSESEKNVKNDISIINKEIKNILNNLEYINRKYNDNYKNVTNLYYTVMHKNMILKKMEFLKKYNNLYNPIDLTIIYYYLKKLKLLNNKRKYLVNKLYILKSRKNILDKINYSFPIDKLNEMFYEHNKKINVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR91</accession>
    <name>A0A1J1GR91_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WD repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00218500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527603.1">
        <property type="nucleotide sequence ID" value="XM_028670896.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR91"/>
    <dbReference type="GeneID" id="39730712"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00218500"/>
    <dbReference type="OMA" id="NECQPNE"/>
    <dbReference type="OrthoDB" id="392215at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="676" mass="80374" checksum="606F92E4E4C375A7" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRA8</accession>
    <name>A0A1J1GRA8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Poly(A) RNA polymerase mitochondrial-like central palm domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00128500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526400.1">
        <property type="nucleotide sequence ID" value="XM_028674806.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRA8"/>
    <dbReference type="GeneID" id="39729810"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00128500"/>
    <dbReference type="OMA" id="IHLEINN"/>
    <dbReference type="OrthoDB" id="273917at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031499">
        <property type="term" value="C:TRAMP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043634">
        <property type="term" value="P:polyadenylation-dependent ncRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05402">
        <property type="entry name" value="NT_PAP_TUTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054708">
        <property type="entry name" value="MTPAP-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045862">
        <property type="entry name" value="Trf4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23092:SF15">
        <property type="entry name" value="INACTIVE NON-CANONICAL POLY(A) RNA POLYMERASE PROTEIN TRF4-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23092">
        <property type="entry name" value="POLY(A) RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22600">
        <property type="entry name" value="MTPAP-like_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Poly(A) RNA polymerase mitochondrial-like central palm" evidence="2">
        <location>
            <begin position="212"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="564"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="565"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="600"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="945" mass="113656" checksum="19B62A502F9FA36A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRK2</accession>
    <name>A0A1J1GRK2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Elongation factor 1-gamma, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00249300</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the GST superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527906.1">
        <property type="nucleotide sequence ID" value="XM_028671234.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRK2"/>
    <dbReference type="GeneID" id="39731021"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00249300"/>
    <dbReference type="OMA" id="TQYFSWT"/>
    <dbReference type="OrthoDB" id="249703at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03044">
        <property type="entry name" value="GST_N_EF1Bgamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1010:FF:000001">
        <property type="entry name" value="Elongation factor 1-gamma 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000148">
        <property type="entry name" value="Elongation factor 1B gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1010">
        <property type="entry name" value="Translation elongation factor EF1B, gamma chain, conserved domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050802">
        <property type="entry name" value="EF-GSTs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001662">
        <property type="entry name" value="EF1B_G_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036433">
        <property type="entry name" value="EF1B_G_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43986">
        <property type="entry name" value="ELONGATION FACTOR 1-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43986:SF1">
        <property type="entry name" value="ELONGATION FACTOR 1-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00647">
        <property type="entry name" value="EF1G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01183">
        <property type="entry name" value="EF1G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89942">
        <property type="entry name" value="eEF1-gamma domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50040">
        <property type="entry name" value="EF1G_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3 9" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="2 3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="7">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="8">
        <location>
            <begin position="86"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="EF-1-gamma C-terminal" evidence="6">
        <location>
            <begin position="239"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="204"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="204"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG95093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="399" mass="46780" checksum="CE139649AE81BB39" modified="2017-02-15" version="1">MDLKLLAPKNDIRSLKVQVVASFCNLKLNIPQFTLGKDDKSEEFLRYSPLGRLPVLLTSNGSLFESNAICKYLCNLRREHNLLGQGVFEEAQVNMWIDFNTYELEIPICCYVTNKSCEKSLNHIKDSFNCLNNHLLLNQFMVGNYITLADLFICVIIMFALKSEKLDVSFLKKYKNLNRLFETVSNQKQFKYVFSDSTVKKPQEKNKKVETKPIDKKKKNSDDEDQLLDDELTEKKPKKVNPLDLLPPSTFSLDDWKYKFSNEKDLLNNAMPHFWKTFDNNGWSLYYMKYDKLEDECQISFVACNMAGGFLQRLENNFSKYSFAVVTVLGENKSYDIEGVWLFRGVDIPFEMKDHPSFEYHIFTKLNINNNDDRKLVEDYWCSKETINNRPVVDRKVWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRM4</accession>
    <name>A0A1J1GRM4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">LRR4.1</name>
        <name evidence="3" type="ORF">PGAL8A_00258800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527996.1">
        <property type="nucleotide sequence ID" value="XM_028671334.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRM4"/>
    <dbReference type="GeneID" id="39731117"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00258800"/>
    <dbReference type="OMA" id="NNCIGSK"/>
    <dbReference type="OrthoDB" id="1904536at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050576">
        <property type="entry name" value="Cilia_flagella_integrity"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45973:SF35">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45973">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14580">
        <property type="entry name" value="LRR_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52075">
        <property type="entry name" value="Outer arm dynein light chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="250" mass="29922" checksum="9F01325529189A31" modified="2017-02-15" version="1">MEYILSNEEIKRVIEKNEIYYSVIELNDVLYLNNKLYRRIEKLQNLQNLKTLYLNNNALEHINGLDCCINLIALYLNCNKISKIENLDSLKKLRILNLEDNNIYVIENLDNLNYLEDLNLSNNCIGSKGFSNIANLHNNKYLSILNLSNNQINEDILENLVHFKNLSILYLMNNPILLKYKNYRKLFLHKLKKLTFLDYKPIKKEERRCVEAFFEGGFKKEQEEMDKIKKQKKIKHENAVEYFRKYIMNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRR5</accession>
    <name>A0A1J1GRR5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcription factor with AP2 domain(S), putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ApiAP2</name>
        <name evidence="3" type="ORF">PGAL8A_00142800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526544.1">
        <property type="nucleotide sequence ID" value="XM_028674965.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729952"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00142800"/>
    <dbReference type="OrthoDB" id="10584701at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2050">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1532"/>
            <end position="1553"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1424"/>
            <end position="1451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1770" mass="212059" checksum="10A65314A3244166" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRT0</accession>
    <name>A0A1J1GRT0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nuclear speckle splicing regulatory protein 1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00171500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NSRP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526829.1">
        <property type="nucleotide sequence ID" value="XM_028670037.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRT0"/>
    <dbReference type="GeneID" id="39730242"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00171500"/>
    <dbReference type="OMA" id="QYLGYKG"/>
    <dbReference type="OrthoDB" id="446635at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000381">
        <property type="term" value="P:regulation of alternative mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018612">
        <property type="entry name" value="NSRP1_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09745">
        <property type="entry name" value="NSRP1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nuclear speckle splicing regulatory protein 1 N-terminal" evidence="4">
        <location>
            <begin position="178"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="35"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="297" mass="36365" checksum="63860D6E95C09F7F" modified="2017-02-15" version="1">MKINLSFSKKNKNENKNEEKNVMDIFSLSDDEETFNFENNQNKKIQEEKEKEIEEKIKEYIYEHENPIKEKCNQDEREINEKKNQKKIQYLGYKGDELTKLNKEKINTEENKIYTQKHKRERQSESDKYQKYEKYHKEEYNNKCKNKNKKHRENYEPKNILNKKEIEKEISIDEIYMKKDNNNNNNNNKSKSKYMDALINSAKRRALEKEILIQKKLKIDTKKEEKVFITNAYKKKMMDRELIKKDIEEEQKENMKDTQSNYNLNSFLKNMSIPLNYNRNNRKPYYDSTNLSDYEKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRU4</accession>
    <name>A0A1J1GRU4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nuclear segregation protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00146000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526576.1">
        <property type="nucleotide sequence ID" value="XM_028675002.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRU4"/>
    <dbReference type="GeneID" id="39729984"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00146000"/>
    <dbReference type="OMA" id="AYFEQCG"/>
    <dbReference type="OrthoDB" id="10261749at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042175">
        <property type="term" value="C:nuclear outer membrane-endoplasmic reticulum membrane network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008298">
        <property type="term" value="P:intracellular mRNA localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039604">
        <property type="entry name" value="Bfr1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31027:SF2">
        <property type="entry name" value="LEBERCILIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31027">
        <property type="entry name" value="NUCLEAR SEGREGATION PROTEIN BFR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="332"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="429"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="15"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="170"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="383"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="333"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="448" mass="53243" checksum="58A03E2C997D89F9" modified="2017-02-15" version="1">MTEAEKIKEVEKPDFDAYNEKLASISESIDEIKKKIDNLQKEIKVASKAKEEYNKKKKDIVTKIDSFQNEIDKLENERRSILDDIEKKQKHKKELKFNAQNIKKQIGFENEEDIEKKIKEIENKLMTSTISIKEEKLLINQIQALNKNKPLLSSYSKIENEANKYDDEAILPLKSRMDSIREQINKLRNEKKLERNKLKELQNSFQEKNNKLNELNSLRDNYSKKMNNYFMERRNITVEMEKKRQQYRNYKLNLLQAKQQKLKEERERKNLELEKQSLEKEMEDIDLLPYREELALIENMLVYLKKIQEEVKIEESKKQNNSIKKVNGEIESVDNKEESNANSKGKNENKKTKNKKEKQKLFKLDMNILCYFVTAGINPPVSFEEVDSCIEKLNEKKEMYEKKRDESVKNVESRRADLSNKIKEIDEKLSLYKPQEQPKGSKTSKIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS00</accession>
    <name>A0A1J1GS00_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DOP1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00004800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the DOP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528094.1">
        <property type="nucleotide sequence ID" value="XM_028671442.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728570"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00004800"/>
    <dbReference type="OMA" id="DYNYNCK"/>
    <dbReference type="OrthoDB" id="297643at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006895">
        <property type="term" value="P:Golgi to endosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040314">
        <property type="entry name" value="DOP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007249">
        <property type="entry name" value="DOP1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14042">
        <property type="entry name" value="DOPEY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14042:SF24">
        <property type="entry name" value="PROTEIN DOPEY-1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04118">
        <property type="entry name" value="Dopey_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="677"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="716"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="domain" description="DOP1 N-terminal" evidence="7">
        <location>
            <begin position="14"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1656"/>
            <end position="1837"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="2685"/>
            <end position="2708"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="305"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="793"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1656"/>
            <end position="1810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1817"/>
            <end position="1837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="2696"/>
            <end position="2708"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00046326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3024" mass="362913" checksum="5A6A9D3498496AC5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSC0</accession>
    <name>A0A1J1GSC0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00165500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526768.1">
        <property type="nucleotide sequence ID" value="XM_028675214.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730181"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00165500"/>
    <dbReference type="OMA" id="KIQIMTM"/>
    <dbReference type="OrthoDB" id="371556at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="493"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1125"/>
            <end position="1156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2865" mass="347182" checksum="582D4D3E45E7CD92" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSJ9</accession>
    <name>A0A1J1GSJ9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">6-cysteine protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">B9</name>
        <name evidence="2" type="ORF">PGAL8A_00399200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527109.1">
        <property type="nucleotide sequence ID" value="XM_028670348.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSJ9"/>
    <dbReference type="GeneID" id="39732522"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00399200"/>
    <dbReference type="OMA" id="CYIGWSF"/>
    <dbReference type="OrthoDB" id="370787at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013244170" evidence="1">
        <location>
            <begin position="24"/>
            <end position="807"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="807" mass="96321" checksum="6336431DB782FA3D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSL5</accession>
    <name>A0A1J1GSL5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00271800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000041">
        <property type="protein sequence ID" value="CRG95517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528326.1">
        <property type="nucleotide sequence ID" value="XM_028671700.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731249"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00271800"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="293"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="371"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="507"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
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            <end position="714"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="776"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1270"/>
            <end position="1326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="380"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="424"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="457"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="507"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="691"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="704"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="776"/>
            <end position="801"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1468" mass="171839" checksum="DFAACF2161331697" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSM2</accession>
    <name>A0A1J1GSM2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Plasmoredoxin, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00002900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528075.1">
        <property type="nucleotide sequence ID" value="XM_028671420.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSM2"/>
    <dbReference type="GeneID" id="39728551"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00002900"/>
    <dbReference type="OMA" id="NLPSFMI"/>
    <dbReference type="OrthoDB" id="409136at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004791">
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:negative regulation of protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:negative regulation of Wnt signaling pathway"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
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    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46472">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46472:SF1">
        <property type="entry name" value="NUCLEOREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13905">
        <property type="entry name" value="Thioredoxin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin-like fold" evidence="1">
        <location>
            <begin position="45"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="176" mass="21453" checksum="64AD7FFD63400577" modified="2017-02-15" version="1">MKCEVDETFLKSTKIDEEKYKNYINYMYYYHNNELKKIDSSYFNDKYLGLFFGASWCKYCLTFVENLNIFKKNFPFIEIIYIPFDKTYQDYLSFLKNMNFYSLPFDNYLYICQKFQIKNLPSFMLISPNNKVLVKDAVQLIKTETYINNLKSLIKNNTIHPNNFKFNNRFLDLFYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSP4</accession>
    <name>A0A1J1GSP4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00403200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Apicomplexa</taxon>
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            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    </dbReference>
    <dbReference type="GeneID" id="39732562"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00403200"/>
    <dbReference type="OMA" id="NMVNMHN"/>
    <dbReference type="OrthoDB" id="371359at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016035">
        <property type="term" value="C:zeta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030559">
        <property type="entry name" value="PolZ_Rev3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45812">
        <property type="entry name" value="DNA POLYMERASE ZETA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45812:SF1">
        <property type="entry name" value="DNA POLYMERASE ZETA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="38"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1145"/>
            <end position="1210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
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            <end position="2953"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
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            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="45"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
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            <begin position="58"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1166"/>
            <end position="1204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
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            <begin position="2318"/>
            <end position="2329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2330"/>
            <end position="2339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="2924"/>
            <end position="2947"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3220" mass="388135" checksum="54D37F54981B3BBC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT59</accession>
    <name>A0A1J1GT59_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00268100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000037">
        <property type="protein sequence ID" value="CRG95479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_028671659.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT59"/>
    <dbReference type="GeneID" id="39731211"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00268100"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="138" mass="16550" checksum="802F6F418D5C890A" modified="2017-02-15" version="1">MKTFTLCLKLFTFLLLIWIFHCFYHYDFSSCLIYKDTLLIKNRIKDERMLAEGGILEKKQTCIKECSEHYPSSEGGFYVIGYVYLIYMLIKCYNTIILSMFKEEDFFKKESDMRYKCIDKILNAYRNNISGEKELEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT74</accession>
    <name>A0A1J1GT74_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00269700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000039">
        <property type="protein sequence ID" value="CRG95496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528305.1">
        <property type="nucleotide sequence ID" value="XM_028671676.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT74"/>
    <dbReference type="GeneID" id="39731228"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00269700"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006496">
        <property type="entry name" value="CHP01606_Plasmodium_spp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09688">
        <property type="entry name" value="Wx5_PLAF3D7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013221429" evidence="2">
        <location>
            <begin position="23"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="288" mass="33732" checksum="1C976BAC59A98142" modified="2017-02-15" version="1">MKTLILFLKIITFLLLIWMYQCFYNCDSDKSLVDKNILQTKNKLKFERVLAEGDIAGKKQTYAKECIEESPLGNKKNKCENPVRYENPYDHWNKVTTPILREEFDEETAGMDPKWREQKWNNEWNKISANKVNNLSSIFHRSDITEEEKKELILRVMSELFSEFQKFIDECKKEMIDNKTYSVSKNEMIDNEAESESKKEMIGNKTESESKKEMIGNKTESESKKEMIGNKTESEYKKEMIDNKAESESKNEMTENKTESESKNEIIDNKTESESKNEMTDGCSGTLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTC7</accession>
    <name>A0A1J1GTC7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00275000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528361.1">
        <property type="nucleotide sequence ID" value="XM_028671738.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTC7"/>
    <dbReference type="GeneID" id="39731282"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00275000"/>
    <dbReference type="OrthoDB" id="286301at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.90.20.10">
        <property type="entry name" value="Plasmodium vivax P25 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012294785" description="EGF-like domain-containing protein" evidence="4">
        <location>
            <begin position="20"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="355"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="5">
        <location>
            <begin position="150"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="210"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="159"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="373" mass="43567" checksum="9F44F403BCE79705" modified="2017-02-15" version="1">MLNFKLINFLIVYIFFVYAHESLNETIDAQRELDNFYLCDYKCDTGEICIYTNEQNNIYKCIKKEEYDKELKIDENKSSKKRNSNKCKNEKNCEISSTYKKKIPKSFLCNNRESKKCENQICLKNKNKIMCLCPSGQKFENNKCTDMVVINKKCPEHLCDNYATCFLNESQMKFKCICDEGYWGFGNVCFPLKNSLSNEGRKKKKKNRKQKNDNVENKEKPIIESDKENLENIGTTNDSIYNIDKTEKIQNLSRKKRILNDEDCKIDCGLNGICIKRKNYEFCICTSGYSSNLENNFLCEEHCKVNNGGCDPNATCESVSSENEEANNVIRKVGVICKCKNGDTRYNGYYCSSSYLMKFNFFILILFFLYLFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTE0</accession>
    <name>A0A1J1GTE0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquinol-cytochrome-c reductase complex assembly factor 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00401900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CBP3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527136.1">
        <property type="nucleotide sequence ID" value="XM_028670378.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTE0"/>
    <dbReference type="GeneID" id="39732549"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00401900"/>
    <dbReference type="OMA" id="MKMYFYI"/>
    <dbReference type="OrthoDB" id="10253878at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034551">
        <property type="term" value="P:mitochondrial respiratory chain complex III assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021150">
        <property type="entry name" value="Ubiq_cyt_c_chap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007129">
        <property type="entry name" value="Ubiqinol_cyt_c_chaperone_CPB3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12184">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX ASSEMBLY FACTOR 1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12184:SF1">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX ASSEMBLY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03981">
        <property type="entry name" value="Ubiq_cyt_C_chap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquinol-cytochrome c chaperone" evidence="2">
        <location>
            <begin position="104"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="292" mass="35388" checksum="E69BB327916BDE59" modified="2017-02-15" version="1">MWNKGRILLLNRRYKNFRYFISDIKVYDNLKVNESKKLYEDKNTKISIQESSKYAIPIPQCDRSIISSFIYKIFLKHTEYGECAWRLIHLIIERLENEEIIKLFRINESFNMKMYFYILHLWIINKRLRQENYQGDIINTYIFDITWRIVRDWLLLKNIPEYTFNAELLNCQEYAFGFLVSLDEAASKVDIFPSLLKDILWEHLYEKKVKKGGKIVTELSKYSILQLRHIFNLSSDYFLEAYFIWADFYNQKKSNRRLPALSQQISYGGYRPKDKSRYLPYDDGKKLLPRTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU08</accession>
    <name>A0A1J1GU08_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00298900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528585.1">
        <property type="nucleotide sequence ID" value="XM_028671987.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU08"/>
    <dbReference type="GeneID" id="39731522"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00298900"/>
    <dbReference type="OMA" id="ILEYHFI"/>
    <dbReference type="OrthoDB" id="370732at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="420"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="526" mass="62140" checksum="DDF76041F0AB8A8F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU28</accession>
    <name>A0A1J1GU28_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CH-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00221900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527637.1">
        <property type="nucleotide sequence ID" value="XM_028670934.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU28"/>
    <dbReference type="GeneID" id="39730746"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00221900"/>
    <dbReference type="OMA" id="IKWLQYL"/>
    <dbReference type="OrthoDB" id="62528at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051493">
        <property type="term" value="P:regulation of cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010441">
        <property type="entry name" value="CH_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052111">
        <property type="entry name" value="Spermatogenesis_Ciliary_MAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12509">
        <property type="entry name" value="SPERMATOGENESIS-ASSOCIATED 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12509:SF8">
        <property type="entry name" value="SPERMATOGENESIS-ASSOCIATED PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06294">
        <property type="entry name" value="CH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CH-like" evidence="2">
        <location>
            <begin position="7"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="154"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="771" mass="92303" checksum="2202009D5A24F73B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU34</accession>
    <name>A0A1J1GU34_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nucleosome assembly protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">NAPL</name>
        <name evidence="4" type="ORF">PGAL8A_00318000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the nucleosome assembly protein (NAP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528775.1">
        <property type="nucleotide sequence ID" value="XM_028672197.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU34"/>
    <dbReference type="GeneID" id="39731713"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00318000"/>
    <dbReference type="OMA" id="AAECKQN"/>
    <dbReference type="OrthoDB" id="27325at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1120.90:FF:000004">
        <property type="entry name" value="Nucleosome assembly protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.90">
        <property type="entry name" value="Nucleosome assembly protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037231">
        <property type="entry name" value="NAP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002164">
        <property type="entry name" value="NAP_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11875">
        <property type="entry name" value="TESTIS-SPECIFIC Y-ENCODED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00956">
        <property type="entry name" value="NAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143113">
        <property type="entry name" value="NAP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="292"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="292"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="326"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="338"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="348" mass="40734" checksum="F95A7927858EF8FC" modified="2017-02-15" version="1">MATTENNQPIPAEEEKEISSLLESIKIDDEKMTDLTEEQKETLKKLKLYQKEYYDYESKFEYELFLLRQKYHDLYDPIYDKRREALVGNGEAKIGTPNLPEFWLRALRNNNTVNHVIEDHDEEILVYLNDIRCDYIKKNKEKKEGFILSFHFAPNPFFSNTVLTKTYHMKCVDCDNEPVLLHTEATVIDWYDNKNILKKNVVKKQHNKNSREVKTVQQTVNRDSFFHFFTSHKVPNSNVIKQLSKHEVAQLEMIIEGDYEVALTIKERIIPYAVDYYLGIIIESESNSIVSDVDSSYSSSENNSNYNSYESNNSAYNDENSNVDTNEYDDNEEDDEEGAKSNEEPLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU79</accession>
    <name>A0A1J1GU79_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00322800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000049">
        <property type="protein sequence ID" value="CRG96015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528823.1">
        <property type="nucleotide sequence ID" value="XM_028672252.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU79"/>
    <dbReference type="GeneID" id="39731761"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00322800"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="205" mass="24785" checksum="2FDCE522B727B31D" modified="2017-02-15" version="1">MKTLILYLKITTFLLLIWMYQCFYNCDSYKTLIDKNILQTKNELKYERVLTEGDIAGQKQTNAERCKEECPVEKKKKEKKIKYWHFPLIRQNPYNRWQVVNNPALFERLKNETSGMDPKWIDHKWNNEWNKISENKVNELSEIFKRSGIPKEEKDKLILGVKEELFRLFQEFLDDCKKEMRGNKTETESKKEMRDNITESNSKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU93</accession>
    <name>A0A1J1GU93_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00307700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528673.1">
        <property type="nucleotide sequence ID" value="XM_028672084.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731610"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00307700"/>
    <dbReference type="OMA" id="NNDIHIC"/>
    <dbReference type="OrthoDB" id="372510at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1211"/>
            <end position="1234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1219"/>
            <end position="1230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1834" mass="220906" checksum="11BED59B14558669" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUB2</accession>
    <name>A0A1J1GUB2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Exonuclease, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00333600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the 5'-3' exonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528926.1">
        <property type="nucleotide sequence ID" value="XM_028672367.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUB2"/>
    <dbReference type="GeneID" id="39731866"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00333600"/>
    <dbReference type="OMA" id="CASWCWE"/>
    <dbReference type="OrthoDB" id="372487at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004534">
        <property type="term" value="F:5'-3' RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18673">
        <property type="entry name" value="PIN_XRN1-2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027073">
        <property type="entry name" value="5_3_exoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041412">
        <property type="entry name" value="Xrn1_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004859">
        <property type="entry name" value="Xrn1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341:SF7">
        <property type="entry name" value="5'-3' EXORIBONUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341">
        <property type="entry name" value="5'-&gt;3' EXORIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17846">
        <property type="entry name" value="XRN_M"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03159">
        <property type="entry name" value="XRN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xrn1 N-terminal" evidence="6">
        <location>
            <begin position="43"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="Xrn1 helical" evidence="7">
        <location>
            <begin position="406"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="Xrn1 helical" evidence="7">
        <location>
            <begin position="499"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="289"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="289"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="667" mass="79792" checksum="370DDD9F825C2F94" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUM4</accession>
    <name>A0A1J1GUM4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">PPM3</name>
        <name evidence="12" type="ORF">PGAL8A_00214200</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527560.1">
        <property type="nucleotide sequence ID" value="XM_028670848.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUM4"/>
    <dbReference type="GeneID" id="39730669"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00214200"/>
    <dbReference type="OMA" id="NAMDQND"/>
    <dbReference type="OrthoDB" id="10264738at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF803">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="11">
        <location>
            <begin position="21"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG94745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="409" mass="47328" checksum="91E95D6A68B27B73" modified="2017-02-15" version="1">MSRLNLISTKEVSEIVSWYTHVCAGTMQGYRTTEEDVTVILASLKNFPSCRMCTIFDGHIGKETALYCARNIANFIGNCESLDSHNIVNACIQMDNEILNSNFANSGSTAIIAIIEKIVHEDFFKLYICNLGDSRAMLIKNDGSFVSLSEDHKPYNKKEKERINKIGGFVENGRILGYIGVSRSFGDKNYKKNCNFPYNPYETMITCIPDIKIFYANYDDILFLGCDGIFETLSWNDVAKFSYKCINGYTLSDAVINILDYALLSGSKDNITIQIIKFFNEKMDNFYFREKLVPSIYIHNEEITKYEFYGNFLNKYHINDKNIINNLVESCAEIKGKYCSIEPFLKKIRENKNVHIILNRRNKKNIKHLTLPILQEDLITNNVFNKMNQTDFNKMIEFFIEYDRKKMLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUN4</accession>
    <name>A0A1J1GUN4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00340700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528994.1">
        <property type="nucleotide sequence ID" value="XM_028672442.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUN4"/>
    <dbReference type="GeneID" id="39731937"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00340700"/>
    <dbReference type="OMA" id="KIFICLN"/>
    <dbReference type="OrthoDB" id="377495at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="451"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="483"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="528"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="570"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="603"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="14"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="669" mass="82277" checksum="AD399B36F64F247E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUW3</accession>
    <name>A0A1J1GUW3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00223000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527648.1">
        <property type="nucleotide sequence ID" value="XM_028670946.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUW3"/>
    <dbReference type="GeneID" id="39730757"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00223000"/>
    <dbReference type="OMA" id="HYTWLAL"/>
    <dbReference type="OrthoDB" id="391977at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="74" mass="9042" checksum="57945D498910C7BF" modified="2017-02-15" version="1">MIIKKKKKNLIHFTWLALIIIPSFYFKNLVYDSFLSLKFDKNKKKIYNKISVYNPIQKNNIEEMNNYILNNNFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUW9</accession>
    <name>A0A1J1GUW9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00324800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000052">
        <property type="protein sequence ID" value="CRG96035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528843.1">
        <property type="nucleotide sequence ID" value="XM_028672274.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUW9"/>
    <dbReference type="GeneID" id="39731781"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00324800"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="310"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="342" mass="40715" checksum="73324A3B0DDD9A70" modified="2017-02-15" version="1">MAFLNNEGCEHSEGDLTKCFMNICEINLNKFEASYCRIERPVVDIKKTSNNNLNDLSKNLFTYEFTPANFHSRIIILSNNDKDGILLLYEYNPHHNKYPDKTYLCRLRNINQKLTLCEAVNIEYFGRSLTFKSYDIINEENKKINISLKNPNHKIIKSKYDELIFKEHYCHHMKTKYISHCNKRYTICKKMNNDQLHCSDANYSGHLIRLDYNEYPILKRNYIYLPSSCLKENLNPVCTPYMCISRAFDEFFQCEYEEISVIKNIMPINNIRPINKLRSIHIIEPNSKNLPVMSLKHKDISHKNSFDNTALFAMSFMSFLVIFIFFFCLLYRTFRKKRRKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV66</accession>
    <name>A0A1J1GV66_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00339800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528985.1">
        <property type="nucleotide sequence ID" value="XM_028672432.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV66"/>
    <dbReference type="GeneID" id="39731928"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00339800"/>
    <dbReference type="OMA" id="YKIISCI"/>
    <dbReference type="OrthoDB" id="372298at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="26"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="168"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="363" mass="43692" checksum="9035167C0681FF87" modified="2017-02-15" version="1">MKNFERNNENIQISTSINDNLEIPLLIKKQLNLRDLRCKNKDLSKKNADIKKTLEEKEKSFSLKEKIYNENREKIIKEYQQAMKDNYDRQIILEEKIKNKEKKIKLFDIEIKKYIVTIGQMRERIKKASCDTQEREKSLSFLSKFKDNSTEFVQLDMFDRLETIFNSREFIQKKKEKLKAKINIIKDKIKDIEEKNNLALMNKELEYKNLVQASEVVLEKEKKIEERLRDNINEHNKRALLLNKIILCIDNFLSRFSSFLPELRHYNIKKNEEKINLEKKNKTQDIMDDMQFLDIADFNNLEEEILKKLDIIYKYIKDTLYIINKAKKEISLKDDNPMEYMKNNLDENIEFFTYNGNVKGKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVJ2</accession>
    <name>A0A1J1GVJ2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SNARE protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SYN6</name>
        <name evidence="3" type="ORF">PGAL8A_00414200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529366.1">
        <property type="nucleotide sequence ID" value="XM_028672855.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVJ2"/>
    <dbReference type="GeneID" id="39732672"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00414200"/>
    <dbReference type="OMA" id="RQSTACL"/>
    <dbReference type="OrthoDB" id="428895at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15841">
        <property type="entry name" value="SNARE_Qc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="2">
        <location>
            <begin position="136"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="225" mass="26626" checksum="D9673FB0F8E3D464" modified="2017-02-15" version="1">MDLWEKDYQKALENGKEIKKILRKNEKEKKKAKNRAILRGKITEFNQNIKFLTHQLNNDYIKNDKIYQRNEAKYKSKISILEKLKKDISILYEDFTLTNDGEVSFSINMENLNGFDNENDLYINDLNKEELLLKQQSLIKLQDEQLNFLEGTTHNLKNISYSINNELNVHNELLDDIDKDIDETNNLLNRNRNIFTRVTSNTSNYFLYVIIAILTTTLILFIIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVM8</accession>
    <name>A0A1J1GVM8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00373400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529314.1">
        <property type="nucleotide sequence ID" value="XM_028672797.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVM8"/>
    <dbReference type="GeneID" id="39732264"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00373400"/>
    <dbReference type="OMA" id="EYCYICE"/>
    <dbReference type="OrthoDB" id="375106at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="265" mass="31716" checksum="C767572D10A0FE4A" modified="2017-02-15" version="1">MNSLVEYKRIKQAVFNKNNLNLKREILKSEEKEYKNKGHIKNKSNKTSENKTCEISNEENKIQIKKNYTSINEDLDIFHIFQNDIKNDKRSIKYEYCYICECAKPCHCKEENYQYEEDISNCYKEKTMSNIHSNFKVISNLMEKIQENKKKKDTKNNKILKNTTKKDECIQKKNNKKEIKGNLGNYEKFYLEKIKITKLKLDNLRNGENGDEELVKGKDIEKKMIFNNQNNIEERLAALKDIEKKHLQLLLDLFEEYVDIEEKIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW12</accession>
    <name>A0A1J1GW12_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">SNARE protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">YKT6.1</name>
        <name evidence="11" type="ORF">PGAL8A_00423400</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endomembrane system</location>
            <topology evidence="7">Lipid-anchor</topology>
            <orientation evidence="7">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the synaptobrevin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529458.1">
        <property type="nucleotide sequence ID" value="XM_028672957.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW12"/>
    <dbReference type="GeneID" id="39732766"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00423400"/>
    <dbReference type="OMA" id="MINEIYM"/>
    <dbReference type="OrthoDB" id="27923at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14824">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.50">
        <property type="entry name" value="Longin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010908">
        <property type="entry name" value="Longin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042855">
        <property type="entry name" value="V_SNARE_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45806">
        <property type="entry name" value="SYNAPTOBREVIN HOMOLOG YKT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45806:SF1">
        <property type="entry name" value="SYNAPTOBREVIN HOMOLOG YKT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13774">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00957">
        <property type="entry name" value="Synaptobrevin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01270">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50859">
        <property type="entry name" value="LONGIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50892">
        <property type="entry name" value="V_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0488">Methylation</keyword>
    <keyword evidence="4" id="KW-0564">Palmitate</keyword>
    <keyword evidence="6" id="KW-0636">Prenylation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Longin" evidence="9">
        <location>
            <begin position="7"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="V-SNARE coiled-coil homology" evidence="10">
        <location>
            <begin position="137"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00046278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG96654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="199" mass="23539" checksum="74E5773993F6E5AD" modified="2017-02-15" version="1">MKLLAIILTKHVDDVIFLCNATDLNSYSFIKRKTFKEGAFFVARTIPSRIEYNTKEIITHENNTVFAFKYFDNICPIVITSDNYPERIAFYMINEIYRDFINTIPKNEWMEIKQDNKITFNLNTYLEKYKDPLNCDAITQTNIKINENIEKVRVSMDSLIKNRENLDVLVDKSKDLSTSTKQLFKQSKKLKKKQCCRMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWE7</accession>
    <name>A0A1J1GWE7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00282600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528437.1">
        <property type="nucleotide sequence ID" value="XM_028671823.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731359"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00282600"/>
    <dbReference type="OMA" id="KIKPLWF"/>
    <dbReference type="OrthoDB" id="377410at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1125"/>
            <end position="1160"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="332"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1814"/>
            <end position="1841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1125"/>
            <end position="1136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1137"/>
            <end position="1150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1873" mass="224534" checksum="3880DBFD953FC3EE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWF3</accession>
    <name>A0A1J1GWF3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Bacterial histone-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00417200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529395.1">
        <property type="nucleotide sequence ID" value="XM_028672887.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWF3"/>
    <dbReference type="GeneID" id="39732703"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00417200"/>
    <dbReference type="OrthoDB" id="370433at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13832">
        <property type="entry name" value="IHF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="entry name" value="IHF-like DNA-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175">
        <property type="entry name" value="DNA-BINDING PROTEIN HU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175:SF3">
        <property type="entry name" value="DNA-BINDING PROTEIN HU-BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="IHF-like DNA-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012385027" evidence="3">
        <location>
            <begin position="18"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="188" mass="22661" checksum="08673839A425520A" modified="2017-02-15" version="1">MYAALYLFFFIFKIVYSRKAFINVHKNNIINKKISVSNPYNKNVLYQSSSKVPVSQVITKKQIIEEVSMETKENKKTVEKIMNGIFDNIYKHLENNEKIYIHKFGVYYNVFRKKRCIKNMRTKEDIHIESSHMPHFKFSKIFKDLIKMNIKIKKDKSDDDENELEEENFHKENINESFKENVNEKLIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWG2</accession>
    <name>A0A1J1GWG2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Membrane attack complex, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">PLP3</name>
        <name evidence="4" type="ORF">PGAL8A_00436200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529583.1">
        <property type="nucleotide sequence ID" value="XM_028673096.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWG2"/>
    <dbReference type="GeneID" id="39732894"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00436200"/>
    <dbReference type="OMA" id="IAIYPCK"/>
    <dbReference type="OrthoDB" id="5950457at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020864">
        <property type="entry name" value="MACPF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19324:SF33">
        <property type="entry name" value="MUCIN-5AC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19324">
        <property type="entry name" value="PERFORIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01823">
        <property type="entry name" value="MACPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00457">
        <property type="entry name" value="MACPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51412">
        <property type="entry name" value="MACPF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="MACPF" evidence="3">
        <location>
            <begin position="216"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="473"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="478"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="812" mass="92941" checksum="9679705E1831C7E8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWK2</accession>
    <name>A0A1J1GWK2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">3'exoribonuclease, putative</fullName>
            <ecNumber evidence="3">3.1.16.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00015800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNase PH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.16.1" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528200.1">
        <property type="nucleotide sequence ID" value="XM_028671560.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWK2"/>
    <dbReference type="GeneID" id="39728680"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00015800"/>
    <dbReference type="OMA" id="TVCFFHG"/>
    <dbReference type="OrthoDB" id="27298at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071051">
        <property type="term" value="P:poly(A)-dependent snoRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050080">
        <property type="entry name" value="RNase_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953:SF0">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="2">
        <location>
            <begin position="40"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="262" mass="30093" checksum="F1383017F2542C66" modified="2017-02-15" version="1">MSKYRVPLPPYNFKSKIQKIDEEFLKTENFKRINNRKNNEIRDMFIKLGEDGYSDASCFYSLGNTKILCLIYGPKPDSKNATYNKGKVFLDIKSLNMNTYGSNEKSDDDIKSLLIECISNIIILDKYPHCSIYIKCLIIQSDGGCLSAALTCISLALIKAQIQMHDMIISINIHSIICPKTNRVYHLVDLDGLEEKYYRSKYEMNEITLGICLNLRTVCFFHGSGNFFNSKTLEEIISYAECACRSLGYEIKKILKNYILKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWR3</accession>
    <name>A0A1J1GWR3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Probable ATP-dependent 6-phosphofructokinase</fullName>
            <shortName evidence="10">ATP-PFK</shortName>
            <shortName evidence="10">Phosphofructokinase</shortName>
            <ecNumber evidence="10">2.7.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Phosphohexokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00428300</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.</text>
    </comment>
    <comment type="function">
        <text evidence="2">Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>beta-D-fructose 6-phosphate + ATP = beta-D-fructose 1,6-bisphosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6-bisphosphate + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13613"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="EC" id="2.7.1.90"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="10">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Tetramer of two alpha (regulatory) and two beta (catalytic) chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.11" evidence="10"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529507.1">
        <property type="nucleotide sequence ID" value="XM_028673012.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732815"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00428300"/>
    <dbReference type="OMA" id="FMAHYLG"/>
    <dbReference type="OrthoDB" id="537915at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00182"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003872">
        <property type="term" value="F:6-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047334">
        <property type="term" value="F:diphosphate-fructose-6-phosphate 1-phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009749">
        <property type="term" value="P:response to glucose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.450">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.460">
        <property type="entry name" value="Phosphofructokinase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.480">
        <property type="entry name" value="Phosphofructokinase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01980">
        <property type="entry name" value="Phosphofructokinase_II_Long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022953">
        <property type="entry name" value="ATP_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011183">
        <property type="entry name" value="PfpB_PPi_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000023">
        <property type="entry name" value="Phosphofructokinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035966">
        <property type="entry name" value="PKF_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02477">
        <property type="entry name" value="PFKA_PPi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005482">
        <property type="entry name" value="PRK07085.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43650">
        <property type="entry name" value="PYROPHOSPHATE--FRUCTOSE 6-PHOSPHATE 1-PHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43650:SF1">
        <property type="entry name" value="PYROPHOSPHATE--FRUCTOSE 6-PHOSPHATE 1-PHOSPHOTRANSFERASE SUBUNIT BETA 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00365">
        <property type="entry name" value="PFK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00476">
        <property type="entry name" value="PHFRCTKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53784">
        <property type="entry name" value="Phosphofructokinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 10" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphofructokinase" evidence="11">
        <location>
            <begin position="177"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphofructokinase" evidence="11">
        <location>
            <begin position="827"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="309"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="249"/>
            <end position="250"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="278"/>
            <end position="281"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="307"/>
            <end position="309"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="354"/>
            <end position="356"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="415"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="511"/>
            <end position="514"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for substrate specificity; cannot use PPi as phosphoryl donor" evidence="10">
        <location>
            <position position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG96703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1392" mass="157846" checksum="32BA374AC82B2508" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWV2</accession>
    <name>A0A1J1GWV2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00437900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529601.1">
        <property type="nucleotide sequence ID" value="XM_028673116.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWV2"/>
    <dbReference type="GeneID" id="39732912"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00437900"/>
    <dbReference type="OrthoDB" id="378285at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="117"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="338" mass="39107" checksum="E26066E8B5E6EFC2" modified="2017-02-15" version="1">MEESNPRSGIIISIVFYICYFFYFITYSYEITLIFSKKIDFILFCILLLTTMFSIFFISLALMYASFFLIAIITLTEIYEYTGNLLDFILDDEFNKLFLLVRLFATVNFIVFFSIHISNLKKKKKEYLNKVRSQNNKMELNNKKSQNNNNVLRNNSGPINNNIYNENGMPIYQENIYPPQTITPGGYALHPISNPIIPNEKNILASQLNTYNSQYVPSKHYTIKSPNNLNSIGNNQTLNDYNAVNSNLNLPNKHYINPLNNSANVHSYINDINIHSNEHYLVKDGYNLRNNYYDIMNNPRNNNNLPPFTPNNISLENIPYPNSGSINKNNGTYNAYGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWY3</accession>
    <name>A0A1J1GWY3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ras-related protein Rab-2, putative</fullName>
            <ecNumber evidence="8">3.6.5.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RAB2</name>
        <name evidence="8" type="ORF">PGAL8A_00452800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endomembrane system</location>
            <topology evidence="7">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.2" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529751.1">
        <property type="nucleotide sequence ID" value="XM_028673282.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWY3"/>
    <dbReference type="GeneID" id="39733061"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00452800"/>
    <dbReference type="OMA" id="TNATHAC"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003925">
        <property type="term" value="F:G protein activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01866">
        <property type="entry name" value="Rab2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000263">
        <property type="entry name" value="Ras-related protein RABB1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0636">Prenylation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="213" mass="24482" checksum="FE14495B0A36600C" modified="2017-02-15" version="1">MSPYEYLFKYIIIGDTGVGKSCLLLQFTDKRFRADHDLTIGVEFGARLINLDNKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLNRWLDEVRQNSNPHMAIILVGNKCDLERREVTTEEGAQFARQNGLIFLETSAKTAKNVEEAFIYTARKIYDNILEDVYDLSNESYGIKYGPTSQYSRVKLDLPSTPESRSSFNCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX23</accession>
    <name>A0A1J1GX23_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein kinase, putative</fullName>
            <ecNumber evidence="2">2.7.10.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00438900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.10.2" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529611.1">
        <property type="nucleotide sequence ID" value="XM_028673127.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732922"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00438900"/>
    <dbReference type="OMA" id="NNSETHI"/>
    <dbReference type="OrthoDB" id="10252354at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004715">
        <property type="term" value="F:non-membrane spanning protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00180">
        <property type="entry name" value="PKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34495:SF4">
        <property type="entry name" value="UNC-51 LIKE AUTOPHAGY ACTIVATING KINASE 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34495">
        <property type="entry name" value="UNC-51-LIKE AUTOPHAGY-ACTIVATING KINASE 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="2271"/>
            <end position="2563"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2568" mass="298307" checksum="0FAABB2FE2AA206E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX46</accession>
    <name>A0A1J1GX46_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">cGMP-dependent protein kinase</fullName>
            <ecNumber evidence="6">2.7.11.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="29" type="ORF">PGAL8A_00308100</name>
    </gene>
    <organism evidence="29 30">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="29" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="29">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.12"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="29">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.12" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528677.1">
        <property type="nucleotide sequence ID" value="XM_028672090.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX46"/>
    <dbReference type="GeneID" id="39731614"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00308100"/>
    <dbReference type="OMA" id="ESCLADC"/>
    <dbReference type="OrthoDB" id="100546at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004691">
        <property type="term" value="F:cAMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030553">
        <property type="term" value="F:cGMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004692">
        <property type="term" value="F:cGMP-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="CDD" id="cd05572">
        <property type="entry name" value="STKc_cGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000068">
        <property type="entry name" value="cGMP-dependent protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000210">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002374">
        <property type="entry name" value="cGMP_dep_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035014">
        <property type="entry name" value="STKc_cGK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353:SF37">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT PRKX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24353">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000559">
        <property type="entry name" value="cGMP-dep_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00103">
        <property type="entry name" value="CAMPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00888">
        <property type="entry name" value="CNMP_BINDING_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15 23 24" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0140">cGMP</keyword>
    <keyword evidence="17" id="KW-0142">cGMP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="13 29" id="KW-0418">Kinase</keyword>
    <keyword evidence="16" id="KW-0460">Magnesium</keyword>
    <keyword evidence="18" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 23 24" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="30" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="27">
        <location>
            <begin position="58"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="27">
        <location>
            <begin position="176"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="27">
        <location>
            <begin position="295"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="27">
        <location>
            <begin position="418"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="26">
        <location>
            <begin position="541"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="28">
        <location>
            <begin position="799"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="25">
        <location>
            <begin position="831"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="25">
        <location>
            <begin position="832"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="22">
        <location>
            <position position="664"/>
        </location>
    </feature>
    <feature type="binding site" evidence="23 24">
        <location>
            <position position="570"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00022992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00024113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00047298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00047462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="PIRSR" id="PIRSR000559-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="PIRSR" id="PIRSR000559-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="27">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="28">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="29">
        <source>
            <dbReference type="EMBL" id="CRG95869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="30">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="853" mass="97887" checksum="B5639CA27F80028C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXA9</accession>
    <name>A0A1J1GXA9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00477200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529996.1">
        <property type="nucleotide sequence ID" value="XM_028673556.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXA9"/>
    <dbReference type="GeneID" id="39733305"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00477200"/>
    <dbReference type="OrthoDB" id="381967at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="228" mass="27095" checksum="2EF45A4CFCFA6687" modified="2017-02-15" version="1">MVKIGKKLKGFNEGVNIIDNNKDKILEKKNNKEIKNKNNEKIKEEKHTLYFGEIQKKKKEYDDLDFYLKNNNISMLLVLLLCKIITKKPKNICDFIHNELDSLLQCQLDKSKTSNIINKEHNENQNYNEEKKDILKKDNYNKIINYETFLGENYLSLDNILDAVNFIKIENSEKIYFNNLIKIIEIFENPQNKHTLLKENMQLTDSISLNKAINLAKIFYNNYFYNTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXG7</accession>
    <name>A0A1J1GXG7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00483700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530060.1">
        <property type="nucleotide sequence ID" value="XM_028673626.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXG7"/>
    <dbReference type="GeneID" id="39733370"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00483700"/>
    <dbReference type="OrthoDB" id="377468at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="230"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="441" mass="52905" checksum="D2D2ADD1FAAA8BB8" modified="2017-02-15" version="1">MQSYYHKDIKLFFSIENLERIKNFFKNVKGIKGELHKFLNYNDSNEFFFNSNDYIITKKNIKNEKIHENIKNQESTFNKKNSNEKVENETIKNKIGSSNLNYDELYNDENKNESENFFNNKFINDEYEFISEEIFRCLYKNEQNIKYTYKYKLLIEIIIQAIVYSCKIKLNIYKLNLFLSILIMTLYKIMENLKEKKNKKKKTINYFINLLDKNIQYASSEEKIINVYSLDENSEIVNNLEAEKEKINNNNEDNKNAYDKKIKNDKELNKNMDKKVLKNENLVNDNDLNYEIKDLDNSRESSTNKNKENNKEIEDKNLLVLNTDLEKSSNKDTISFQYREAKYIIKYMFENIFSIYNILEYIFLFSSFPFNLTFSNNCSFISPIETFSINDQIQLNKDEINDDKFTTNSYIKEVLNIPFFVLDKFYNNIDELKEKINSIIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXR1</accession>
    <name>A0A1J1GXR1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Early transcribed membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ETRAMP</name>
        <name evidence="2" type="ORF">PGAL8A_00492700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530150.1">
        <property type="nucleotide sequence ID" value="XM_028673726.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXR1"/>
    <dbReference type="GeneID" id="39733460"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00492700"/>
    <dbReference type="OrthoDB" id="10490004at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09716">
        <property type="entry name" value="ETRAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="334" mass="39487" checksum="4DCB69020FAB9C8A" modified="2017-02-15" version="1">MKILRIFNFYNIVLLASFIILHSSNESLSTKKKLSEFKEIEEKLKKKKSNKKIIIIICTTVGLVISSYLLGRVIYNKVTKRKYKSRIESDKTNFDNDNKFSRGYNNILSFVNNYLDNEFYAASDKNKSMMKNYSYLRKVINNAQHHFKEVLSDNELKCMLSNLYKRMNVKYSDFLSNKNNKIKAKDSNKNISTSISSFNHDIVAFSESINENYEQILNLAKKAKKQLKDDFLRSSDHIKNTPPKIIYTKRLVEFITSREGYELSKKQISELCKYVHVTSMELYYDHISKINPIYEKPKLKTYDLDINLFSTLNKKNMENYKEKIFLEVENFEQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXS5</accession>
    <name>A0A1J1GXS5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Translation initiation factor IF-3, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">IF3b</name>
        <name evidence="1" type="ORF">PGAL8A_00494100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530164.1">
        <property type="nucleotide sequence ID" value="XM_028673741.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXS5"/>
    <dbReference type="GeneID" id="39733474"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00494100"/>
    <dbReference type="OrthoDB" id="375742at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036788">
        <property type="entry name" value="T_IF-3_C_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55200">
        <property type="entry name" value="Translation initiation factor IF3, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="1" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="306" mass="36985" checksum="628C222973758BCA" modified="2017-02-15" version="1">MNVFLLNKKLILLPTCNLKILCDICRLFYSYFTNNFFFQDKCFIKNINYSENTDYQRYLYNNILKNCFFFLKKKKNTLNENSKKNVEEKTNDDIRSKNKEDSEIKKDELINCEIDKDEINKVIKNKKIKKYEIINNIKENDTFSSNTENDKYCSFNKKEVLNSTNYKSSIYYNFDPSLKTKRIQIYYNCEMYDMERKIKKIKNLLMNGFPVDILLIYNTDNIINKSSEKQNKKFKQEENEKNKIHETNKITKFVETEKLKQTKYSLHIYIKTNLILNSIKNISVVDQIFRHFKNRNHIILIKVYPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY29</accession>
    <name>A0A1J1GY29_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00474700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000092">
        <property type="protein sequence ID" value="CRG97168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529971.1">
        <property type="nucleotide sequence ID" value="XM_028673527.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733280"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00474700"/>
    <dbReference type="OrthoDB" id="348930at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="487"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1491"/>
            <end position="1547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="487"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="511"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="554"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1685" mass="198860" checksum="2A69B7734E2FC057" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY51</accession>
    <name>A0A1J1GY51_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00496800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530191.1">
        <property type="nucleotide sequence ID" value="XM_028673772.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY51"/>
    <dbReference type="GeneID" id="39733501"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00496800"/>
    <dbReference type="OMA" id="ITKHINR"/>
    <dbReference type="OrthoDB" id="372440at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="58" mass="7276" checksum="9ED6BC3C12F48B6E" modified="2017-02-15" version="1">MLFFFDLAFLKNIRRNFISLNSILYSKRTWQTNMKRKTYRSKKRKKYIRIGETLIRIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY79</accession>
    <name>A0A1J1GY79_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcription factor with AP2 domain(S), putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ApiAP2</name>
        <name evidence="1" type="ORF">PGAL8A_00501300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530241.1">
        <property type="nucleotide sequence ID" value="XM_028673827.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY79"/>
    <dbReference type="GeneID" id="39733546"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00501300"/>
    <dbReference type="OrthoDB" id="405976at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2050">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="320" mass="38904" checksum="F62BB79A6C76C7ED" modified="2017-02-15" version="1">MIFRYYSSVILYKHEKNELSIKLKYFLKNGLKNHFNNKTSNNYSTYRIKNDINDLKNVNLYLLNKKLMNQKSFLFFHYNKKNYSINKDVYMKKWNFFYNEKRSFSGRSGGLKRKKKRKEERLVNNCSAKRLEFFYPKKKRRQRIGIIQNSRKNIVYDNILKRFLVYYYKQGIQVFRSFSCKKKKNFESARNKAIILSKQFQKRYSNEKGDNEKEKNKKPLNVNDSNLIAKYNNDLIKQIKIIPDKNKSGYRGVFYDPSHHAYICVYNEAGIRKFQIFKIQNNDYLEAYNLAVMCRRYKLFKNFQFVAQRNRIRSGRVHLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYG9</accession>
    <name>A0A1J1GYG9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Calmodulin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00519100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530419.1">
        <property type="nucleotide sequence ID" value="XM_028674025.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYG9"/>
    <dbReference type="GeneID" id="39733724"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00519100"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF0">
        <property type="entry name" value="CALMODULIN LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0007">Acetylation</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="13"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="166"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00020786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="242" mass="29012" checksum="F6BCD5624C11C528" modified="2017-02-15" version="1">MEYEGEIFHLTEYQIKKSIKAFNYLDKKKKGLLKFDLLGNLLRCCGYNVSLKEIEKIKEKIIEMKIIEKKKEQKSNEEVEKREKDIIIYNENDELSNNNQFSQNDITNDDNNNISQLLSNLKNYDNFIEIEKKKEEIKKEEEKNKNLFSLKEYFRIIQIPNITNEIKPPNILDAFEIFDEQGNGKISIKKLRFILQYLGEPFSNSEFDEFFEWIKTLDKVYKNDYIIYEDLLNELINKDSNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYJ7</accession>
    <name>A0A1J1GYJ7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Serine/threonine protein kinase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00511400</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530342.1">
        <property type="nucleotide sequence ID" value="XM_028673939.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYJ7"/>
    <dbReference type="GeneID" id="39733647"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00511400"/>
    <dbReference type="OMA" id="MLNASMP"/>
    <dbReference type="OrthoDB" id="10252354at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF82">
        <property type="entry name" value="KP78A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="107"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG97541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="366" mass="42488" checksum="B875207DD2CDD69C" modified="2017-02-15" version="1">MYLGSVQNIEDNFLCKGEYKQVYLCLNKNGNNDVIKIDISYDNNIYDILQLGREKYGAHGEYVTDSCGNIIQSIRDIIDGDTLYLKEKKDKYHFLYKMKNILIVNDYIVEKRIGSGGFGIVFQGIHTQTKQKVALKFIPKSNFLDVTDVHRVFIEIQTLRGLIHNNIIKMYDVNHFQNYVCLIMEYAVNGDLKNYILKNNGYLSEKEAHDLFLQIVKGVYYCHSKHIVHRDLKLENILLDENMTCKIADFGLSDFVNVDQNIKTEAGTKAYIAPEIIFNQTINYSVFKLDIWSLGILLFIMTQGFAPFQNFEKGLKYFESSTLKYANDVSDDLKNLISLMLNIDPNKRPIIVEILNHKWFYNYSCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYN4</accession>
    <name>A0A1J1GYN4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00525200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530477.1">
        <property type="nucleotide sequence ID" value="XM_028674090.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYN4"/>
    <dbReference type="GeneID" id="39733785"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00525200"/>
    <dbReference type="OrthoDB" id="370332at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="331"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="358"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="403" mass="48251" checksum="B5A3AC24662F9008" modified="2017-02-15" version="1">MSETSACPLNDFFDIDEENNLDEIKKEDTQIYNGNFLTYIYKQLECCCLNFFDELDKKNKRKNITLKKNYIEDYNKNRKNICEFSVFDKILKKNGDLITEVPLDSKYFNPHADWCECIHELEVELNNEEVEFCIFHFFLKMYRSESRDKDLLLSIILECLYSKKDFKKEYYGQRGDFKFLKEIKNIETSNFKESLNELVNIIENTNFIECNRNKEVKTNGSKKNNEKFYFKLYIIIKIKYSYGIYIFNCDDTYDIVVIDCNTFNKNKPKIMSFFSMRKFISFLNNIYSINFSGENTYGSFPIIVYESRECYASSHKHLSLKSSVCKKKKKSKKRNILNKRSTEENNEEDYENEHNNDNDDDDNDDDDNDEEDDDEEDIDDEDDDDEDIDDDNDEEQNKYEVKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYV1</accession>
    <name>A0A1J1GYV1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">arginine--tRNA ligase</fullName>
            <ecNumber evidence="4">6.1.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Arginyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PGAL8A_00533200</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>tRNA(Arg) + L-arginine + ATP = L-arginyl-tRNA(Arg) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:20301"/>
            <dbReference type="Rhea" id="RHEA-COMP:9658"/>
            <dbReference type="Rhea" id="RHEA-COMP:9673"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78513"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.19"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.19" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530555.1">
        <property type="nucleotide sequence ID" value="XM_028674175.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYV1"/>
    <dbReference type="GeneID" id="39733865"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00533200"/>
    <dbReference type="OMA" id="HHIGDWG"/>
    <dbReference type="OrthoDB" id="68056at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004814">
        <property type="term" value="F:arginine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006420">
        <property type="term" value="P:arginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000116">
        <property type="entry name" value="Arginine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.730.10:FF:000006">
        <property type="entry name" value="Arginyl-tRNA synthetase 2, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.70">
        <property type="entry name" value="Arginyl tRNA synthetase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00123">
        <property type="entry name" value="Arg_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001278">
        <property type="entry name" value="Arg-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005148">
        <property type="entry name" value="Arg-tRNA-synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036695">
        <property type="entry name" value="Arg-tRNA-synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035684">
        <property type="entry name" value="ArgRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008909">
        <property type="entry name" value="DALR_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00456">
        <property type="entry name" value="argS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956:SF5">
        <property type="entry name" value="ARGININE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956">
        <property type="entry name" value="ARGINYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03485">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05746">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00750">
        <property type="entry name" value="tRNA-synt_1d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01038">
        <property type="entry name" value="TRNASYNTHARG"/>
    </dbReference>
    <dbReference type="SMART" id="SM01016">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00836">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55190">
        <property type="entry name" value="Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 13 16" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arginyl tRNA synthetase N-terminal" evidence="15">
        <location>
            <begin position="6"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="DALR anticodon binding" evidence="14">
        <location>
            <begin position="473"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="CRG97754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="587" mass="68497" checksum="4D5CF57EAB6CBF19" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYX2</accession>
    <name>A0A1J1GYX2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00508400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530312.1">
        <property type="nucleotide sequence ID" value="XM_028673906.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYX2"/>
    <dbReference type="GeneID" id="39733617"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00508400"/>
    <dbReference type="OMA" id="HIWRLIE"/>
    <dbReference type="OrthoDB" id="390194at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="263" mass="31319" checksum="1E4CAD7E6F592D20" modified="2017-02-15" version="1">MKKTISYTQYKIKNSDSNYYLYELYKSVENCKSGNLLFKLTHKALNYQIHDLHIWRLIEHKFYELQKELTPKEISLIINYFKQIKINDSKIYENSIDIILSSIDKYSIHDLSLICLSFTYFNKINTNFMNKLADAIIKLYERDKNNIQNLSKKELYNIFISYVHIIGSYSKIKHKNIELFKIASLYIHCALNSDINIPSKIIIKIINSYTNVKIKHSKLFDLIAKQIPILKITDEELKNIKDSFEKLKYSDETLDKYIHYRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ01</accession>
    <name>A0A1J1GZ01_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine/arginine-rich splicing factor 12, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SRSF12</name>
        <name evidence="4" type="ORF">PGAL8A_00024600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530611.1">
        <property type="nucleotide sequence ID" value="XM_028674238.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ01"/>
    <dbReference type="GeneID" id="39728769"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00024600"/>
    <dbReference type="OMA" id="YSNERYS"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000691">
        <property type="entry name" value="Serine/arginine-rich splicing factor 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050441">
        <property type="entry name" value="RBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48034">
        <property type="entry name" value="TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="12"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="123"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="141"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="174"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="269"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="313" mass="38572" checksum="C2196E328085F50F" modified="2017-02-15" version="1">MGPYINQKNQPMSLLIRKLKYDTSPSMVREKFKKFGAIKDVYLPIDYYTKEPRGFGFVEFYDAKDAEQALKEMNGSEIDGNRIEVFVAQKGRSDPKLMKYKEKGAYAYRKNPDNKIRRRYISKSNSRYRSYSRDKIRRRDRSREKFRYRNSYDKRMGNYRDKKNYYMKNYNKYRNRDYERSFSRSRRSRDYKNDYPRYRDRKRYDRYYRSNSRRRLSRQDKYDYRNKHDKKEDNYKSKCNSNDEFSDETRNSSKHSKNHNISKSISFNTEKDDARKKNENINEKDNSNAWKESENRNTTNNKRDFMNSNEEFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ25</accession>
    <name>A0A1J1GZ25_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Enhancer of polycomb-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00513200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530360.1">
        <property type="nucleotide sequence ID" value="XM_028673959.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ25"/>
    <dbReference type="GeneID" id="39733665"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00513200"/>
    <dbReference type="OMA" id="EKPTHYI"/>
    <dbReference type="OrthoDB" id="435275at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024943">
        <property type="entry name" value="Enhancer_polycomb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14898">
        <property type="entry name" value="ENHANCER OF POLYCOMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="620"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="620"/>
            <end position="638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="644" mass="77279" checksum="8DA572A05D34D55A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ99</accession>
    <name>A0A1J1GZ99_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA replication licensing factor MCM4</fullName>
            <ecNumber evidence="7">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">MCM4</name>
        <name evidence="10" type="ORF">PGAL8A_00513400</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the MCM2-7 complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530362.1">
        <property type="nucleotide sequence ID" value="XM_028673961.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ99"/>
    <dbReference type="GeneID" id="39733667"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00513400"/>
    <dbReference type="OMA" id="GRQNECK"/>
    <dbReference type="OrthoDB" id="10251574at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902975">
        <property type="term" value="P:mitotic DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008047">
        <property type="entry name" value="MCM_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF66">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01660">
        <property type="entry name" value="MCMPROTEIN4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 7" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="9">
        <location>
            <begin position="504"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="718"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="718"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="738"/>
            <end position="754"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU368062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG97561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="952" mass="108883" checksum="11A31B0098D61549" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZB9</accession>
    <name>A0A1J1GZB9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00022700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530593.1">
        <property type="nucleotide sequence ID" value="XM_028674218.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZB9"/>
    <dbReference type="GeneID" id="39728750"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00022700"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="144" mass="17613" checksum="7B5CBC70AE6A1028" modified="2017-02-15" version="1">MNTRNTCRIFIILFFFYLNFLLQNKPIFYGQAVFEKSIDNFYIRFLAEKETYDKKLTKPSESYKRVDKSTCSKFSNERKGIYNAEIKYLRSTSIKQIVQERPFDSNLYESEKDVRRRKWEKNKEMKKNEQEKKERRKERALKGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZE7</accession>
    <name>A0A1J1GZE7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00026000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530625.1">
        <property type="nucleotide sequence ID" value="XM_028674253.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728783"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00026000"/>
    <dbReference type="OMA" id="IYTSYDI"/>
    <dbReference type="OrthoDB" id="371641at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1843"/>
            <end position="1866"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2948"/>
            <end position="2978"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3884"/>
            <end position="3927"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="969"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2172"/>
            <end position="2199"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3616"/>
            <end position="3650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1844"/>
            <end position="1853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1854"/>
            <end position="1866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2948"/>
            <end position="2963"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="3884"/>
            <end position="3910"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="4898" mass="585159" checksum="3742B29A0A1AFC4E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZH4</accession>
    <name>A0A1J1GZH4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GINS complex subunit Psf3, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00427700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529501.1">
        <property type="nucleotide sequence ID" value="XM_028673005.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZH4"/>
    <dbReference type="GeneID" id="39732809"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00427700"/>
    <dbReference type="OrthoDB" id="374114at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000811">
        <property type="term" value="C:GINS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902975">
        <property type="term" value="P:mitotic DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11713">
        <property type="entry name" value="GINS_A_psf3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036224">
        <property type="entry name" value="GINS_bundle-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010492">
        <property type="entry name" value="GINS_Psf3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038437">
        <property type="entry name" value="GINS_Psf3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22768">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22768:SF0">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158573">
        <property type="entry name" value="GINS helical bundle-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="208" mass="24856" checksum="0CC8F35F14AC5CEE" modified="2017-02-15" version="1">MNEDIIKNIKLNNNFLEFEEIIKDINTPFNFIDLVEIPCIPIVDLYGLSLLNNEAYLEYKSGLREDKINADDEIKLTLFFAVKLYKKNIIRIKFPSYYDIIETLKFDPVSVTIGLFNQFYFETAYELCNLLPVNEWPSANFYNILRKAEKTRIHFLINNKTKLNSYFLEGLTNKEKKIYKYFLEGTSKEREMLNKETTLFYFYEKEKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZM5</accession>
    <name>A0A1J1GZM5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">60S ribosomal protein L28, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00370000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529280.1">
        <property type="nucleotide sequence ID" value="XM_028672760.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZM5"/>
    <dbReference type="GeneID" id="39732230"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00370000"/>
    <dbReference type="OMA" id="WELTKKN"/>
    <dbReference type="OrthoDB" id="338850at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002672">
        <property type="entry name" value="Ribosomal_eL28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029004">
        <property type="entry name" value="Ribosomal_eL28/Mak16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10544">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01778">
        <property type="entry name" value="Ribosomal_L28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal eL28/Mak16" evidence="5">
        <location>
            <begin position="8"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="80"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="128" mass="15044" checksum="8C838383D4BB5EC6" modified="2017-02-15" version="1">MSNISNALIWELTKKNSCFLKKNKRGGSRVFSCDPYNVYCKNTPSNSGLVKDNCINVRILKRKPVLLVKKLNEKNGVVTKECKTKNIKNVEKLIEEYGKNEKEKNKRKLLKKYKRLFKVYCNTRKRNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZM7</accession>
    <name>A0A1J1GZM7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00433500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529557.1">
        <property type="nucleotide sequence ID" value="XM_028673067.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732867"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00433500"/>
    <dbReference type="OMA" id="DFTHDIH"/>
    <dbReference type="OrthoDB" id="384673at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034394">
        <property type="term" value="P:protein localization to cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026160">
        <property type="entry name" value="Ric3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21723:SF3">
        <property type="entry name" value="PROTEIN RIC-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21723">
        <property type="entry name" value="RESISTANCE TO INHIBITORS OF CHOLINESTERASE PROTEIN 3 RIC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011955599" evidence="3">
        <location>
            <begin position="25"/>
            <end position="1344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1111"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="54"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="811"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1114"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1133"/>
            <end position="1143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1344" mass="164407" checksum="480485C9A52AD920" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZW7</accession>
    <name>A0A1J1GZW7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Calponin-homology (CH) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00442300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529645.1">
        <property type="nucleotide sequence ID" value="XM_028673164.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZW7"/>
    <dbReference type="GeneID" id="39732956"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00442300"/>
    <dbReference type="OMA" id="LKLANWE"/>
    <dbReference type="OrthoDB" id="193300at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051493">
        <property type="term" value="P:regulation of cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000059">
        <property type="entry name" value="RIKEN cDNA 6430531B16 gene"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010441">
        <property type="entry name" value="CH_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052111">
        <property type="entry name" value="Spermatogenesis_Ciliary_MAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12509:SF9">
        <property type="entry name" value="SPERM FLAGELLAR PROTEIN 1 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12509">
        <property type="entry name" value="SPERMATOGENESIS-ASSOCIATED 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06294">
        <property type="entry name" value="CH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="1">
        <location>
            <begin position="15"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="209" mass="24842" checksum="ADD6A528553F4045" modified="2017-02-15" version="1">MNKNDLIKTVSKIKEEELNDLYEWLNSFTLSRKIKNIHRDFSDGVLMAELVNVCLPKFVELHNYSKAHSINQKKYNWNTLNEKVFKRLGFKIDKKGVEEIVNCKYMGVEKVLHTFKNQLNKFQNETKDENLNISHEEKEKAISEKENLPLNKENDILNEMNSDFLNNDEIIKILKDKIFNLEKLLKIKDSKIEILNRKIDTLSRMKNHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0V0</accession>
    <name>A0A1J1H0V0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00051200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530874.1">
        <property type="nucleotide sequence ID" value="XM_028674530.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0V0"/>
    <dbReference type="GeneID" id="39729037"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00051200"/>
    <dbReference type="OMA" id="TSIIHWR"/>
    <dbReference type="OrthoDB" id="369406at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="151" mass="17628" checksum="8EF9509B093751FD" modified="2017-02-15" version="1">MVIQIFSKKKNCKYVSYESEHILFLSSFQLAFALMFCIYCELYYLSIMNVGLLTTSLLHWNKPELGLRRSIDILMAIMNIIIHIIYSFQINIYCVLICFISTILVTTSYLIGKKFSYNSYSAIFHLFIHTTGNFTALTIYYYAKKKSINSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1I1</accession>
    <name>A0A1J1H1I1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Antigen UB05, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00496600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530189.1">
        <property type="nucleotide sequence ID" value="XM_028673770.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1I1"/>
    <dbReference type="GeneID" id="39733499"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00496600"/>
    <dbReference type="OMA" id="YMFSEFY"/>
    <dbReference type="OrthoDB" id="439796at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="125" mass="14683" checksum="DD0E21B5A57326E7" modified="2017-02-15" version="1">MGSHIQASRFLDSAVLSLFAMIISASFLYMFSEFYTLSIESKIFNNKISLILSRLFPFKKTFEYNLTHILLLTICIIILSLKPDYDFHNKINVKESTNKNIQNKEEYSQESEESDTKRKAREKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1S5</accession>
    <name>A0A1J1H1S5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome c oxidase copper chaperone, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">COX17</name>
        <name evidence="9" type="ORF">PGAL8A_00484900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COX17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530072.1">
        <property type="nucleotide sequence ID" value="XM_028673639.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1S5"/>
    <dbReference type="GeneID" id="39733382"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00484900"/>
    <dbReference type="OMA" id="HKACMRK"/>
    <dbReference type="OrthoDB" id="1915887at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016531">
        <property type="term" value="F:copper chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.1130:FF:000006">
        <property type="entry name" value="Cytochrome c oxidase copper chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1130">
        <property type="entry name" value="CytochromE C oxidase copper chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009069">
        <property type="entry name" value="Cys_alpha_HP_mot_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007745">
        <property type="entry name" value="Cyt_c_oxidase_Cu-chaperone"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16719">
        <property type="entry name" value="CYTOCHROME C OXIDASE COPPER CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16719:SF0">
        <property type="entry name" value="CYTOCHROME C OXIDASE COPPER CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05051">
        <property type="entry name" value="COX17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47072">
        <property type="entry name" value="Cysteine alpha-hairpin motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4 8" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR607745-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG97270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="66" mass="7717" checksum="A80F643E5CEF9ED3" modified="2017-02-15" version="1">MGTFLNKPIKNTNEEIKGEKKKKICCVCLETKKLRDECIVKLGEEQCKKFIDDHNQCLRNEGFDIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H399</accession>
    <name>A0A1J1H399_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">60S ribosomal protein L31, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPL31</name>
        <name evidence="4" type="ORF">PGAL8A_00025000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530615.1">
        <property type="nucleotide sequence ID" value="XM_028674242.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H399"/>
    <dbReference type="GeneID" id="39728773"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00025000"/>
    <dbReference type="OMA" id="EVWKQGI"/>
    <dbReference type="OrthoDB" id="9739313at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00463">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.440.10:FF:000001">
        <property type="entry name" value="60S ribosomal protein L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000054">
        <property type="entry name" value="Ribosomal_eL31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020052">
        <property type="entry name" value="Ribosomal_eL31_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023621">
        <property type="entry name" value="Ribosomal_eL31_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10956">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10956:SF0">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01198">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01380">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54575">
        <property type="entry name" value="Ribosomal protein L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01144">
        <property type="entry name" value="RIBOSOMAL_L31E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="119" mass="14004" checksum="3B951FD822AC9899" modified="2017-02-15" version="1">MVKGTKKQKKTLQPITKFITINLSKLTHKVCYKRKAPRAIKEIRNIAGKLMHTKDVRLDVKLNKFIWSKGIRNPPKRVRVKLERKRNEDEDSKEKMYTIVQHVMVDSFKGLVNECEANE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3Y1</accession>
    <name>A0A1J1H3Y1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphopantothenoylcysteine synthetase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00063000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530988.1">
        <property type="nucleotide sequence ID" value="XM_028674658.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3Y1"/>
    <dbReference type="GeneID" id="39729155"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00063000"/>
    <dbReference type="OrthoDB" id="70224at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10300">
        <property type="entry name" value="CoaB-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035929">
        <property type="entry name" value="CoaB-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102645">
        <property type="entry name" value="CoaB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG98191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="494" mass="59270" checksum="DB40176BE8F1C70F" modified="2017-02-15" version="1">MKSYFSEYPNFFNEKLRPNNLNEILKKLEKFIENEHVIFITSGGTKVPLEKAEIRNIDNFSTGRRGALICEYLLKINKKVIFLHRKGSIIPFEYHLKSFIRMDNIDVVDNKIAFNLNEEEQNILMDNIKNYKKYSKNVFFISFNTVFEYGYYLIEICNLLNENLNKKYTNYLNIIKTEQIFNCNSLDQPYAKNFFNDLLFFFTNYKVCHKLNEQKASKLLENLIIFQRLYSEKNQNNNSIQDIENSFNYISSILNIIIKNKEYILLEEHKENIILKINLLIGKMNYTENYVIDQILNENKNENKNENKNENISKCKDSYKKEHLNEKNNSNKNLKKHDIFKENEYLNSNVKKNNENKLKGLFITSHLVILCAAASDFYIPFNELYENKIESNNSLHLNMWLTPKFYKIIKKYFLLLKLCIFKLENDEKKLIEKSNERIQYADMLIANVLTERYNFVYIFNKEFDYFLLKKAEYEPIENQICNYICKHFNYMKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2012-05-16" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>H7CDY8</accession>
    <name>H7CDY8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Open reading frame 105</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ORF105</name>
        <name evidence="3" type="ORF">PGAL8A_API03800</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <geneLocation type="apicoplast" evidence="2"/>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Mol. Biol. Evol." volume="29" first="2095" last="2099">
            <title>The Plasmodium Apicoplast Genome: Conserved Structure and Close Relationship of P. ovale to Rodent Malaria Parasites.</title>
            <authorList>
                <person name="Arisue N."/>
                <person name="Hashimoto T."/>
                <person name="Mitsui H."/>
                <person name="Palacpac N.M.Q."/>
                <person name="Kaneko A."/>
                <person name="Kawai S."/>
                <person name="Hasegawa M."/>
                <person name="Tanabe K."/>
                <person name="Horii T."/>
            </authorList>
            <dbReference type="PubMed" id="22396524"/>
            <dbReference type="DOI" id="10.1093/molbev/mss082"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">A8</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">8A</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AB649424">
        <property type="protein sequence ID" value="BAL70758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LN835293">
        <property type="protein sequence ID" value="CRG98248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009325475.1">
        <property type="nucleotide sequence ID" value="NC_031963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="H7CDY8"/>
    <dbReference type="GeneID" id="30315793"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_API03800"/>
    <dbReference type="OMA" id="MIFNIHY"/>
    <dbReference type="OrthoDB" id="392910at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Apicoplast API"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0933">Apicoplast</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0934">Plastid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAL70758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="105" mass="13207" checksum="F441F5BE7DC87128" modified="2012-05-16" version="1">MIFNLYSKLKKNLLLKKFKNINIIKYNINKKIYIKYLNIIFKSKNSNNYIYNKINYNYKNIKLLYIISNKYNLLLIKIINFWYILLYYKINYHNIYLIKNIFTYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKS4</accession>
    <name>A0A1J1GKS4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00070400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525822.1">
        <property type="nucleotide sequence ID" value="XM_028673976.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKS4"/>
    <dbReference type="GeneID" id="39729229"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00070400"/>
    <dbReference type="OrthoDB" id="377467at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="949" mass="114918" checksum="B6EB36D00025942F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKX1</accession>
    <name>A0A1J1GKX1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protoheme IX farnesyltransferase, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Heme O synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00066700</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UbiA prenyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG92963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525785.1">
        <property type="nucleotide sequence ID" value="XM_028675111.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKX1"/>
    <dbReference type="GeneID" id="39729192"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00066700"/>
    <dbReference type="OMA" id="HFYSIAY"/>
    <dbReference type="OrthoDB" id="5211at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008495">
        <property type="term" value="F:protoheme IX farnesyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006784">
        <property type="term" value="P:heme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13957">
        <property type="entry name" value="PT_UbiA_Cox10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="entry name" value="UbiA prenyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00154">
        <property type="entry name" value="CyoE_CtaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006369">
        <property type="entry name" value="Protohaem_IX_farnesylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030470">
        <property type="entry name" value="UbiA_prenylTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01473">
        <property type="entry name" value="cyoE_ctaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43448">
        <property type="entry name" value="PROTOHEME IX FARNESYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43448:SF2">
        <property type="entry name" value="PROTOHEME IX FARNESYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00943">
        <property type="entry name" value="UBIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="242"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="271"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="366"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG92963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="488" mass="56989" checksum="9C1EDC43807BB040" modified="2017-02-15" version="1">MKKNSLLMNVTKYMIIDGNNFIINKKKNLFLDGYEFSTLKRNSLIKKTGILNKDIYIKKSSGIILNLEHLYKKYICSNQILGKDSLKYYSEEKKNLKNLEDLDLHKNNEYIKDDKKNEGILMINNKNNRDTLSNNINFSNRLLEKNIISIQKNNRKINSNILKYYLNNYLELSKSKLTLWVTLSSTFGYFMLGGSSLKEFSALVVGVFLCSSSANTFNQIRERNIDKIMKRTQKRPLANNKISLKHAEIFGFTSAITGSLILYFFNNPLTSYLGIFNIILYACLYTPLKLKTPYNTHIGSIVGSIPTLMGCTAVEQNLFLPEPWILFITQFLWQFPHFYSLAYLYKEDYIKGKYKMFPLQDKNGIYTAKLCRPYIIGLSLLPLIFFFCGYTSYMYILTSLIPNLFIYYKFQNFLKKPSKCNIRSFFKHSLWHIILLLALSAYHTQIPDKNENNSRNIKENNKDTKENSLDHSITKFKKKLLKFCIVFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL70</accession>
    <name>A0A1J1GL70_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00000700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000005">
        <property type="protein sequence ID" value="CRG93067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525889.1">
        <property type="nucleotide sequence ID" value="XM_028670122.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL70"/>
    <dbReference type="GeneID" id="39728529"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00000700"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="135" mass="15816" checksum="490B5B153D71E984" modified="2017-02-15" version="1">MESEENYDPHSFEDDDYIKNSHVTIRLNAQDNCDANLPNLPIPNQSEILIEEQNVIINNSPENQGVYIRNNRPGDYMGSFLCSVAFYSTLFFFTIRHLLLNCYRGFRRYNRERSDNDNCNTEQKNHTSNVNNEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLM0</accession>
    <name>A0A1J1GLM0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Vacuolar protein sorting-associated protein 53, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">VPS53</name>
        <name evidence="4" type="ORF">PGAL8A_00097900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526095.1">
        <property type="nucleotide sequence ID" value="XM_028672410.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLM0"/>
    <dbReference type="GeneID" id="39729503"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00097900"/>
    <dbReference type="OMA" id="QQFYHTI"/>
    <dbReference type="OrthoDB" id="10261632at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000938">
        <property type="term" value="C:GARP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039766">
        <property type="entry name" value="Vps53"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007234">
        <property type="entry name" value="Vps53_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12820:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 53 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12820">
        <property type="entry name" value="VACUOLAR SORTING PROTEIN 53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04100">
        <property type="entry name" value="Vps53_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Vps53 N-terminal" evidence="3">
        <location>
            <begin position="40"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="461"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="35"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="461"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="472"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="958" mass="114231" checksum="0A29BA3390C39D6D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLP1</accession>
    <name>A0A1J1GLP1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Small ribosomal subunit protein mS23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00096600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mS23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526082.1">
        <property type="nucleotide sequence ID" value="XM_028672266.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLP1"/>
    <dbReference type="GeneID" id="39729490"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00096600"/>
    <dbReference type="OrthoDB" id="206354at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23701">
        <property type="entry name" value="At1g26750"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059242">
        <property type="entry name" value="mS23_dom"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="214" mass="25716" checksum="32DF9BC22F8AE02D" modified="2017-02-15" version="1">MGKGAVHPNGSNFCRSLKYNIVDKMRMLVETNLYERPRWLEWSERSPPMEIYNISLKSKFNNNKYIDLVKFLLKKYPHLRFQDCFVEGNNNIKGYDFFRNDHIVTQMATHQLYYMNRGYGKKEALEKVEKIFYNRRMELEKQQKINMCLAIDEKIKPLYTNGYSYLYDKMAENEKAHLNIILKKLKNMTEKLKKEKKTNDNNLNLEKNETSKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLX9</accession>
    <name>A0A1J1GLX9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Ribosomal RNA small subunit methyltransferase NEP1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">NEP1</name>
        <name evidence="11" type="ORF">PGAL8A_00114600</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526262.1">
        <property type="nucleotide sequence ID" value="XM_028674265.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLX9"/>
    <dbReference type="GeneID" id="39729671"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00114600"/>
    <dbReference type="OMA" id="ECKFSND"/>
    <dbReference type="OrthoDB" id="269804at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070037">
        <property type="term" value="F:rRNA (pseudouridine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18088">
        <property type="entry name" value="Nep1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1280.10:FF:000003">
        <property type="entry name" value="Ribosomal RNA small subunit methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005304">
        <property type="entry name" value="Rbsml_bgen_MeTrfase_EMG1/NEP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12636">
        <property type="entry name" value="NEP1/MRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12636:SF5">
        <property type="entry name" value="RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE NEP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03587">
        <property type="entry name" value="EMG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="8" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG93440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="227" mass="26558" checksum="4B0B8618D575A9A8" modified="2017-02-15" version="1">MNNEYDLTNISEINKGKKVIIILEGAYLQLIETKRYIYELTNNIKHKYILKERNQKNINDCRPDILHQCLIHLLESPLNKYGMLQVYVKTHDNQLFYVSPHLKIPKTYEQFESLMVTFLRKYKIKANEKSIYLLKIIKNDYNNILPVNGKKIGLSMKGKKVNLSDYVKKFENENVPITFFIGAVAYTNPTMDIEIIDENINISEFSLSAATCCSAICLEFENLWKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM03</accession>
    <name>A0A1J1GM03_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Selenocysteine-specific elongation factor selB, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00106000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526177.1">
        <property type="nucleotide sequence ID" value="XM_028673322.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM03"/>
    <dbReference type="GeneID" id="39729586"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00106000"/>
    <dbReference type="OMA" id="IPFMNKT"/>
    <dbReference type="OrthoDB" id="2067at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001514">
        <property type="term" value="P:selenocysteine incorporation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03696">
        <property type="entry name" value="SelB_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049394">
        <property type="entry name" value="eEFSec_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050055">
        <property type="entry name" value="EF-Tu_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721">
        <property type="entry name" value="ELONGATION FACTOR TU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721:SF11">
        <property type="entry name" value="SELENOCYSTEINE-SPECIFIC ELONGATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21131">
        <property type="entry name" value="eEFSec_4th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="1">
        <location>
            <begin position="1"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="694" mass="80492" checksum="63D2E71339FDB302" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM04</accession>
    <name>A0A1J1GM04_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00112300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526239.1">
        <property type="nucleotide sequence ID" value="XM_028674010.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM04"/>
    <dbReference type="GeneID" id="39729648"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00112300"/>
    <dbReference type="OMA" id="NFMSVRY"/>
    <dbReference type="OrthoDB" id="384883at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="973" mass="116989" checksum="D3894D455A234ECE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM40</accession>
    <name>A0A1J1GM40_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RWD domain-containing protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00116300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526279.1">
        <property type="nucleotide sequence ID" value="XM_028674455.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM40"/>
    <dbReference type="GeneID" id="39729688"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00116300"/>
    <dbReference type="OrthoDB" id="277175at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040213">
        <property type="entry name" value="GIR2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12292">
        <property type="entry name" value="RWD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00591">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RWD" evidence="2">
        <location>
            <begin position="9"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="145"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="228" mass="27291" checksum="05A828BD6BFC0D64" modified="2017-02-15" version="1">MDYKSEQLAEKESLSLLYEHTNEFICLNNNSFKILIENKIKKISFYILFEYTEKYPDESPIYKIVESKNLSSSLKKNVENQIKETIENNLGYSMIYSIVENIRTYILEDIEEKSMYDEMIERQPKSFEEVINENADDNKKDDINYENVLEMKELCEEKYRVTEEEFNAWRKEFYKDIFDVMNNNGNLDNPTGRELFEKGKFNLLDTEYDEGEAKWSNEDLFCDIDLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMA0</accession>
    <name>A0A1J1GMA0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">histone acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">GCN5</name>
        <name evidence="15" type="ORF">PGAL8A_00116500</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetyltransferase family. GCN5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.48" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526281.1">
        <property type="nucleotide sequence ID" value="XM_028674477.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729690"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00116500"/>
    <dbReference type="OMA" id="YIKWNIT"/>
    <dbReference type="OrthoDB" id="1937912at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000123">
        <property type="term" value="C:histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010484">
        <property type="term" value="F:histone H3 acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05509">
        <property type="entry name" value="Bromo_gcn5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000004">
        <property type="entry name" value="Histone acetyltransferase KAT2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037800">
        <property type="entry name" value="GCN5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45750">
        <property type="entry name" value="GH11602P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45750:SF3">
        <property type="entry name" value="HISTONE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0010">Activator</keyword>
    <keyword evidence="10 15" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6 11" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="14">
        <location>
            <begin position="1699"/>
            <end position="1852"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="13">
        <location>
            <begin position="1941"/>
            <end position="2011"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="380"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="675"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1310"/>
            <end position="1396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="383"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="534"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="575"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1321"/>
            <end position="1370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1379"/>
            <end position="1396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG93459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2033" mass="234206" checksum="FCF4C878558B55FB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMA1</accession>
    <name>A0A1J1GMA1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mic1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00127500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526390.1">
        <property type="nucleotide sequence ID" value="XM_028674795.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMA1"/>
    <dbReference type="GeneID" id="39729800"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00127500"/>
    <dbReference type="OMA" id="CQHFANL"/>
    <dbReference type="OrthoDB" id="264532at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035658">
        <property type="term" value="C:Mon1-Ccz1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010506">
        <property type="term" value="P:regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040371">
        <property type="entry name" value="RMC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009755">
        <property type="entry name" value="RMC1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12897">
        <property type="entry name" value="COLON CANCER-ASSOCIATED PROTEIN MIC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12897:SF4">
        <property type="entry name" value="REGULATOR OF MON1-CCZ1 COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07035">
        <property type="entry name" value="RMC1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mic1" evidence="2">
        <location>
            <begin position="655"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="592"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="592"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="823" mass="97710" checksum="EE6FFBA0074A4795" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMA8</accession>
    <name>A0A1J1GMA8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Exonuclease, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00117300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526289.1">
        <property type="nucleotide sequence ID" value="XM_028674566.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMA8"/>
    <dbReference type="GeneID" id="39729698"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00117300"/>
    <dbReference type="OMA" id="WNGKFLY"/>
    <dbReference type="OrthoDB" id="26838at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46814">
        <property type="entry name" value="EGALITARIAN, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46814:SF1">
        <property type="entry name" value="EGALITARIAN, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00474">
        <property type="entry name" value="35EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3'-5' exonuclease" evidence="1">
        <location>
            <begin position="82"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="407" mass="47971" checksum="5C1A6198D2DAA144" modified="2017-02-15" version="1">MKSMKYVCNNNYMKKNKIFYHNLFSINILKKLKNEELIKNFKKFYCEKFTFNVSKKCKTINEDNKTQFALESNNTKNNYKNIKVIENEKDGEKAVEEINQNDIIAVDFEGTNLGKYGKICIMQVYTEKRSKDKSDDEVVEKYYIFDLLKLSVKNSVKKIIENKRTLKLVHDCREDSSALYNQLGIKFENVYDTSIAHMLLMKKKKNNDLYQVSFLQLLNDYLGVKDECLNNIKKEMYKNEKIWEMRPLSKMCIIYALKNVKYLLPLYKIFDNLIPKKEVLEKSRDFINYCFLNSRYKSPNDLAKRGNIIEAMMVSKSMINCVFKLNSTRKGMACTPSSVAQFRDVNVGDVVFCVVSNKSIDQKILYLCKHDDVYDYWNLKERPRGKFKPSIHENIVDPMITICDEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMB8</accession>
    <name>A0A1J1GMB8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00128100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526396.1">
        <property type="nucleotide sequence ID" value="XM_028674802.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMB8"/>
    <dbReference type="GeneID" id="39729806"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00128100"/>
    <dbReference type="OrthoDB" id="369379at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="160" mass="18879" checksum="D0B98EDC839BB456" modified="2017-02-15" version="1">MNKLELDAQCLIRALKYFSKDNSATLSENDCKKIFNKILSQDLNDENIREIIKNIKADIKWNKLNYVENFMLSPSILHILINKQLKKHELEIIFKDFFKCIQTNNVINTNDLKRFLRLCNINISQDSLLYLCKVYLNLEDANQSADYNAFVNMMKKYLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMD4</accession>
    <name>A0A1J1GMD4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Merozoite surface protein 9, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">MSP9</name>
        <name evidence="4" type="ORF">PGAL8A_00129700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526412.1">
        <property type="nucleotide sequence ID" value="XM_028674819.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMD4"/>
    <dbReference type="GeneID" id="39729822"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00129700"/>
    <dbReference type="OMA" id="MKECKHL"/>
    <dbReference type="OrthoDB" id="371803at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0477">Merozoite</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012227307" evidence="3">
        <location>
            <begin position="23"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="501"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="143"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="505"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="529"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="548" mass="63034" checksum="A740464BCF49C87D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMF6</accession>
    <name>A0A1J1GMF6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00122200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526337.1">
        <property type="nucleotide sequence ID" value="XM_028674736.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMF6"/>
    <dbReference type="GeneID" id="39729747"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00122200"/>
    <dbReference type="OMA" id="QNLLNCK"/>
    <dbReference type="OrthoDB" id="423313at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="191" mass="21750" checksum="86A4D662672058C8" modified="2017-02-15" version="1">MDSENIGYNDKQTKYTSNDYGHNEQNETLLMQEAEIVLITTSLGGIKASFFSSLRAQNLLNCKKYVYFVIDTNRDTSTAKNLKDTELFTKWKKDQLLLTNENGVILPQILIDGISIGNDVDLQNLEDEGNLDFIVARLKCPNCLIEKFNTDESCPNCKYDYVSLISDDLIKNNGVIRILQGDLYDEENLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMW0</accession>
    <name>A0A1J1GMW0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">AP-2 complex subunit alpha, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00145900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526575.1">
        <property type="nucleotide sequence ID" value="XM_028674999.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMW0"/>
    <dbReference type="GeneID" id="39729983"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00145900"/>
    <dbReference type="OMA" id="MKCYKYL"/>
    <dbReference type="OrthoDB" id="413467at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030117">
        <property type="term" value="C:membrane coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050840">
        <property type="entry name" value="Adaptor_Complx_Large_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013041">
        <property type="entry name" value="Clathrin_app_Ig-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22780">
        <property type="entry name" value="ADAPTIN, ALPHA/GAMMA/EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49348">
        <property type="entry name" value="Clathrin adaptor appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1054"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="7">
        <location>
            <begin position="25"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="7">
        <location>
            <begin position="340"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="820"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="842"/>
            <end position="865"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1130" mass="133398" checksum="570B4F820B62D33A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMW9</accession>
    <name>A0A1J1GMW9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Protein SYS1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00149800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SYS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526612.1">
        <property type="nucleotide sequence ID" value="XM_028675041.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMW9"/>
    <dbReference type="GeneID" id="39730022"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00149800"/>
    <dbReference type="OMA" id="ISEYICY"/>
    <dbReference type="OrthoDB" id="542931at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006895">
        <property type="term" value="P:Golgi to endosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043001">
        <property type="term" value="P:Golgi to plasma membrane protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034067">
        <property type="term" value="P:protein localization to Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019185">
        <property type="entry name" value="Integral_membrane_SYS1-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12952:SF0">
        <property type="entry name" value="PROTEIN SYS1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12952">
        <property type="entry name" value="SYS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09801">
        <property type="entry name" value="SYS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="45"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG93790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="134" mass="16003" checksum="32CDB20DAC2F2996" modified="2017-02-15" version="1">MLCLQSLYYTISSITIFIFFTIINFSRNLSYIFNTKSYFNGDHALFYIFFINILNSIIMSYPIKLIVKRAKKCLDYVLSYNIIHFILSVLVSGFPISWLWYISFFFNIILCVLISEYICYKEEMKEININNIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN13</accession>
    <name>A0A1J1GN13_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">AP-3 complex subunit beta, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00142100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526537.1">
        <property type="nucleotide sequence ID" value="XM_028674958.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN13"/>
    <dbReference type="GeneID" id="39729945"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00142100"/>
    <dbReference type="OMA" id="PFHQTYL"/>
    <dbReference type="OrthoDB" id="302453at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030117">
        <property type="term" value="C:membrane coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026739">
        <property type="entry name" value="AP_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11134">
        <property type="entry name" value="ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="7">
        <location>
            <begin position="47"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="7">
        <location>
            <begin position="322"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="236"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="246"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1060" mass="124953" checksum="846A1409BE4D2FE2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN20</accession>
    <name>A0A1J1GN20_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Sphingomyelin synthase 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">SMS1</name>
        <name evidence="11" type="ORF">PGAL8A_00153500</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sphingomyelin synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526647.1">
        <property type="nucleotide sequence ID" value="XM_028675080.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN20"/>
    <dbReference type="GeneID" id="39730059"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00153500"/>
    <dbReference type="OMA" id="YECTDLI"/>
    <dbReference type="OrthoDB" id="422827at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047493">
        <property type="term" value="F:ceramide cholinephosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033188">
        <property type="term" value="F:sphingomyelin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045221">
        <property type="entry name" value="Sphingomyelin_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025749">
        <property type="entry name" value="Sphingomyelin_synth-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21290:SF25">
        <property type="entry name" value="SPHINGOMYELIN SYNTHASE-RELATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21290">
        <property type="entry name" value="SPHINGOMYELIN SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14360">
        <property type="entry name" value="PAP2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="127"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="187"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="293"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="322"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="Sphingomyelin synthase-like" evidence="10">
        <location>
            <begin position="266"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF14360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG93826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="462" mass="54412" checksum="76F7AB197D67BB4C" modified="2017-02-15" version="1">MLETNLIENYHFDNLIHNNFDNKRKKEKVIMPIIENKKILIELKNSFNDENLNCKINFNDTKETYYDHSDEVSETNDKIKTNVSISSDIQGDGLLGNIDNYFEKKNGNSEYKEIKSSSFRKKIYKIFFIRLLYAFIYGIIGVYIQCYSIILSDSYYNTGDEPLKDRIHELIKKIPSFMDAGFINGNIMIFFIITILRFGLFFPFLLSLTILIRLIFMLSTIYYVRSLFIYVTTLPCPIPTCQPLKNKGFLDNIYSSHLIIFAQVYECTDLIISGHTAFTTLLKYLWLFYEKNIYIKICICFYSLFIFSIIIISRFHYTVDVLMGYAFGASIFIFYHCLLDIAAKRYAINKSFYVNYCGYSRSFTERCNLFHYLIPLIGYIEALDYRLNISTSYDKEWSSFCPCKPVNSKSLINKKKNIRNEDYYDFSDHFYHSYAGNGAFSLSSIYNLLNKCKNIYRIKNKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN45</accession>
    <name>A0A1J1GN45_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">HECT-domain (Ubiquitin-transferase), putative</fullName>
            <ecNumber evidence="7">6.3.2.19</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00156600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.19" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526679.1">
        <property type="nucleotide sequence ID" value="XM_028675116.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730091"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00156600"/>
    <dbReference type="OMA" id="HYFACAA"/>
    <dbReference type="OrthoDB" id="271273at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042469">
        <property type="entry name" value="HECTD3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46654">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HECTD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46654:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HECTD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="repeat" description="ANK" evidence="2">
        <location>
            <begin position="6750"/>
            <end position="6791"/>
        </location>
    </feature>
    <feature type="domain" description="HECT" evidence="6">
        <location>
            <begin position="8590"/>
            <end position="8861"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="2597"/>
            <end position="2648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="4036"/>
            <end position="4059"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="4228"/>
            <end position="4250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="7535"/>
            <end position="7555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="8541"/>
            <end position="8575"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="5098"/>
            <end position="5132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="2608"/>
            <end position="2620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="2627"/>
            <end position="2648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="4036"/>
            <end position="4057"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="4228"/>
            <end position="4238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="7535"/>
            <end position="7547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="8541"/>
            <end position="8556"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="3">
        <location>
            <position position="8829"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="8875" mass="1044012" checksum="B9F8A2E1C50CF350" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN88</accession>
    <name>A0A1J1GN88_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pyrroline-5-carboxylate reductase</fullName>
            <ecNumber evidence="5">1.5.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00164400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-proline + NADP(+) = (S)-1-pyrroline-5-carboxylate + NADPH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:14109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17388"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="EC" id="1.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the pyrroline-5-carboxylate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.2" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526756.1">
        <property type="nucleotide sequence ID" value="XM_028675201.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN88"/>
    <dbReference type="GeneID" id="39730169"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00164400"/>
    <dbReference type="OMA" id="VWAVKPQ"/>
    <dbReference type="OrthoDB" id="10263291at2759"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00361"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004735">
        <property type="term" value="F:pyrroline-5-carboxylate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3730.10:FF:000001">
        <property type="entry name" value="Pyrroline-5-carboxylate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.10">
        <property type="entry name" value="ProC C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01925">
        <property type="entry name" value="P5C_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053790">
        <property type="entry name" value="P5CR-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029036">
        <property type="entry name" value="P5CR_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000304">
        <property type="entry name" value="Pyrroline-COOH_reductase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00112">
        <property type="entry name" value="proC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645">
        <property type="entry name" value="PYRROLINE-5-CARBOXYLATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645:SF0">
        <property type="entry name" value="PYRROLINE-5-CARBOXYLATE REDUCTASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14748">
        <property type="entry name" value="P5CR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000193">
        <property type="entry name" value="Pyrrol-5-carb_rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00521">
        <property type="entry name" value="P5CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 4 5" id="KW-0521">NADP</keyword>
    <keyword evidence="3 5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyrroline-5-carboxylate reductase catalytic N-terminal" evidence="6">
        <location>
            <begin position="6"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="Pyrroline-5-carboxylate reductase dimerisation" evidence="7">
        <location>
            <begin position="152"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="6"/>
            <end position="11"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>NADPH</name>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="61"/>
            <end position="64"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000193-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="258" mass="28525" checksum="19EA6D6542ECB6A8" modified="2017-02-15" version="1">MENVKLGFGQMGFALANGILQNNIIKKENIYYHDPKKNNNTFNYLNSNEEVIRTCDIIICAVKPDIVSHILKDVGKYLMSKLLISICAGVKIEKLEQLVGKNNKVVRVMPNTPCLVGESASTFCVNKNVNDVDKKYVIDIFSSCGIIHEIEEKYMDITTALVGSGPAYVYLFIESLIDAGVKNGLSRELSKKLVLQTIYGSVKMTNTSNLPVQQLKDNVCSPGGTTAVGLFTLEKNHFKYSIIEAIDAACEKSKLMSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GND3</accession>
    <name>A0A1J1GND3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA sliding clamp PCNA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">PCNA</name>
        <name evidence="16" type="ORF">PGAL8A_00168300</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Auxiliary protein of DNA polymerase delta and is involved in the control of DNA replication by increasing the polymerase processibility during elongation of the leading strand. Involved in DNA damage response.</text>
    </comment>
    <comment type="function">
        <text evidence="12">This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processivity during elongation of the leading strand.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homotrimer. Interacts with ORC1 (via PIP-box motif); the interaction occurs during DNA replication in trophozoites. Interacts with ORC5; the interaction occurs during the trophozoite stage but not at the late schizont stage. Interacts with FEN1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the PCNA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526796.1">
        <property type="nucleotide sequence ID" value="XM_028670001.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GND3"/>
    <dbReference type="GeneID" id="39730209"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00168300"/>
    <dbReference type="OMA" id="EMKLINM"/>
    <dbReference type="OrthoDB" id="534348at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043626">
        <property type="term" value="C:PCNA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030337">
        <property type="term" value="F:DNA polymerase processivity factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006272">
        <property type="term" value="P:leading strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051054">
        <property type="term" value="P:positive regulation of DNA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006275">
        <property type="term" value="P:regulation of DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019985">
        <property type="term" value="P:translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00577">
        <property type="entry name" value="PCNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.150.10:FF:000006">
        <property type="entry name" value="Proliferating cell nuclear antigen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.150.10:FF:000010">
        <property type="entry name" value="Proliferating cell nuclear antigen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.150.10">
        <property type="entry name" value="DNA Polymerase III, subunit A, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00317">
        <property type="entry name" value="DNApol_clamp_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046938">
        <property type="entry name" value="DNA_clamp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000730">
        <property type="entry name" value="Pr_cel_nuc_antig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022649">
        <property type="entry name" value="Pr_cel_nuc_antig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022659">
        <property type="entry name" value="Pr_cel_nuc_antig_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022648">
        <property type="entry name" value="Pr_cel_nuc_antig_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00590">
        <property type="entry name" value="pcna"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11352">
        <property type="entry name" value="PROLIFERATING CELL NUCLEAR ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11352:SF0">
        <property type="entry name" value="PROLIFERATING CELL NUCLEAR ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02747">
        <property type="entry name" value="PCNA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00705">
        <property type="entry name" value="PCNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00339">
        <property type="entry name" value="PCNACYCLIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55979">
        <property type="entry name" value="DNA clamp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01251">
        <property type="entry name" value="PCNA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00293">
        <property type="entry name" value="PCNA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 13" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proliferating cell nuclear antigen PCNA N-terminal" evidence="14">
        <location>
            <begin position="1"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="Proliferating cell nuclear antigen PCNA C-terminal" evidence="15">
        <location>
            <begin position="128"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00055713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00065747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="CRG93975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="274" mass="30587" checksum="0B694C5BD7DCA473" modified="2017-02-15" version="1">MLEAKLNNASILKKLFECIKDLVNDANVDADETGLKLQALDGNHVSLVSLHLLDSGFSHYRCDRERVLGVNIASLNKVFKLCAANESVVISSKDDEDNLNFVFENNKEDKVTNFSLKLMSIELDSLNIPDCEEGFDAEVELSSKELTNIFRNLSEFSDTVFIEIDSNSIKFTTKGLVGDAEVALKPRDSTSEDDIGVNIKSKKKIKQSFAIKYLNLFSKSSILSDVVTLGLSDSRPIEFKYEIKDTSPDADTLKIGFVKFFLAPKMDDDMDNKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNH5</accession>
    <name>A0A1J1GNH5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fam-b protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00153900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526651.1">
        <property type="nucleotide sequence ID" value="XM_028675084.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNH5"/>
    <dbReference type="GeneID" id="39730063"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00153900"/>
    <dbReference type="OMA" id="PLCYRCY"/>
    <dbReference type="OrthoDB" id="372069at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009618923" description="Fam-b protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="340" mass="40736" checksum="DF1AC22606D27DED" modified="2017-02-15" version="1">MTNIIIILIFCLFKVSYENNYNNKEKICYYMNILKKPIFFNYYILRNKRKNSCEYFIKKKKDKSFELFSLKDVLTNSLSDKDINEIKNIFPIINEKLLILDRNNFENVSNSEINDIDDLLIEFNNKHFNLKDIKVKIIDSEKNENDSYFNFVKDENDYLKKKVEILQSSPFNKTCFKSIQGNKCDNYKKNYENNSDVDEELFYELDETLNEKENSTIINGEEILQNINQKTENNENDGKSFYQFLKKFYLVNILSQNPMKIMYKYLEFKEYLSSSKEKLKNFFVKEYHYTTQKIISVLSHDLKKSNETGEENKNKNKGLLSTIFDSIFSLFYFPQKDVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNM7</accession>
    <name>A0A1J1GNM7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Trichohyalin-plectin-homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00159400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526707.1">
        <property type="nucleotide sequence ID" value="XM_028675147.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNM7"/>
    <dbReference type="GeneID" id="39730119"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00159400"/>
    <dbReference type="OMA" id="EREMGIH"/>
    <dbReference type="OrthoDB" id="378893at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043597">
        <property type="entry name" value="TPH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13868">
        <property type="entry name" value="TPH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Trichohyalin-plectin-homology" evidence="3">
        <location>
            <begin position="93"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="87"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="171"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="230"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="353" mass="43385" checksum="226D3713EB2899BE" modified="2017-02-15" version="1">MNLSSNFLSKIKKKKKKRENQLLNEELNKIEEKWLKGDDKKNKGIISSAKREEILEFIQKQDEFKNIKKISIDQKEEETTNKSSRIIKNDNDLLKELQKQIEEKKLRQEKLNEENIKREEIETTYLSEIEKKQKELEKNIILKNKESALIIKNQIHENYLKKQEEERLKIIEGKRMQKQFEKSKIEELEKRQEKIMEQKVLYNYILESNRKHIESSNEKKKEEKKKDEEYVRYLEEKEQREKEYEEKIKKEKEEKEKEIHEIRMKQKKNVELLAHFDDIQAMKWQKEKKIKDEQKRVLEEEEKKKKIDELNNARLIALMEKKKKKLEQLEEDKKEAENLKNIYDLYVFIFEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNQ3</accession>
    <name>A0A1J1GNQ3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Regulator of nonsense transcripts, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PGAL8A_00381700</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA2/NAM7 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526934.1">
        <property type="nucleotide sequence ID" value="XM_028670153.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732347"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00381700"/>
    <dbReference type="OMA" id="VCKKAAN"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21407">
        <property type="entry name" value="1B_UPF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18039">
        <property type="entry name" value="DEXXQc_UPF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21400">
        <property type="entry name" value="ZBD_UPF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000097">
        <property type="entry name" value="Regulator of nonsense transcripts 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040812">
        <property type="entry name" value="UPF1_1B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018999">
        <property type="entry name" value="UPF1_CH/ZBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF364">
        <property type="entry name" value="REGULATOR OF NONSENSE TRANSCRIPTS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18141">
        <property type="entry name" value="UPF1_1B_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09416">
        <property type="entry name" value="UPF1_Zn_bind"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51997">
        <property type="entry name" value="UPF1_CH_RICH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Upf1" evidence="14">
        <location>
            <begin position="180"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="28"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="149"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="C3H" evidence="11">
        <location>
            <begin position="188"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="CC/SHH/C" evidence="11">
        <location>
            <begin position="202"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="C4" evidence="11">
        <location>
            <begin position="248"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="290"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="751"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="58"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="149"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="163"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="296"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="322"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="333"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="352"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG94113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1353" mass="156250" checksum="D91D15C2C34BAC8D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNT3</accession>
    <name>A0A1J1GNT3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00177300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526882.1">
        <property type="nucleotide sequence ID" value="XM_028670096.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNT3"/>
    <dbReference type="GeneID" id="39730300"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00177300"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="222" mass="26071" checksum="1F113521D1183606" modified="2017-02-15" version="1" fragment="single">IFCEIVDTVYLGKTLSFNSIDIIDKKGRENYRIRLKNLKNPKHTSRILNYDDIYFSRDACHYAKEGDFHETVCRYSICTKDQNDHTSCVDAKFNGKLFHLKKHSIHHEGKEKCIYLPNICLNKGFKIDCTPYLCEYERPFELTPCKKLGISIVNNVIPHSESSEVKHTRTKNLVHENNLNMSSLVAMSFIPFLILFFFIGCYMYKIIKENRSRKIKMRSKEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNW7</accession>
    <name>A0A1J1GNW7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">50S ribosomal protein L9, mitochondrial, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00169700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526811.1">
        <property type="nucleotide sequence ID" value="XM_028670017.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNW7"/>
    <dbReference type="GeneID" id="39730224"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00169700"/>
    <dbReference type="OMA" id="KYTYIVL"/>
    <dbReference type="OrthoDB" id="5555409at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.10">
        <property type="entry name" value="Ribosomal protein L9, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000244">
        <property type="entry name" value="Ribosomal_bL9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009027">
        <property type="entry name" value="Ribosomal_bL9/RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020070">
        <property type="entry name" value="Ribosomal_bL9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036935">
        <property type="entry name" value="Ribosomal_bL9_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21368">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01281">
        <property type="entry name" value="Ribosomal_L9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55658">
        <property type="entry name" value="L9 N-domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein L9" evidence="4">
        <location>
            <begin position="45"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="251" mass="30408" checksum="F5D242F8C66D7C52" modified="2017-02-15" version="1">MIKIKEIKFLFNFKKLYMSSYLNYNKYTIKRKTYIAAVENKYTYIILLNNITHIGDKGEIIKIKRGCARNLIKERKAVYATYENVDSYADKEKYKRSQKVDIKKSVLIKEDFEKYFTQLRNIDITIYLDTYKYTNNVSYNLYDFFNYISNNYELDLTHKNLHKINYYKNREDYSNDKKQQIYSDTTNINDLIIQTNSPFKYTGIYVIYFYLFLPNANFLNEIIFRISSLQEYELMKSEKNKKTDIVYSIDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNZ6</accession>
    <name>A0A1J1GNZ6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00383700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526954.1">
        <property type="nucleotide sequence ID" value="XM_028670175.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNZ6"/>
    <dbReference type="GeneID" id="39732367"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00383700"/>
    <dbReference type="OMA" id="ITDIANF"/>
    <dbReference type="OrthoDB" id="361486at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056356">
        <property type="entry name" value="Microp_apicomplexa_17"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23531">
        <property type="entry name" value="Microp_apicomplexa_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="108" mass="12741" checksum="9F25182DD99A2BD1" modified="2017-02-15" version="1">MFICRINLSKKIKEKIPYGVKQSQNYKDAKKQERISLEGARKLKESRGMILEGKKSLFMCLRQNTDINWYRAGQILKHLEIHQRAKPEITPKLREKITNIANFVKKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP10</accession>
    <name>A0A1J1GP10_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Cyclin-dependent kinase 2 homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Cell division control protein 2 homolog</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">cdc2-related kinase 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">MRK</name>
        <name evidence="12" type="ORF">PGAL8A_00390600</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="6">May form a complex composed of at least the catalytic subunit CRK2 and a cyclin.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527023.1">
        <property type="nucleotide sequence ID" value="XM_028670252.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP10"/>
    <dbReference type="GeneID" id="39732436"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00390600"/>
    <dbReference type="OMA" id="MGPEGFT"/>
    <dbReference type="OrthoDB" id="1732493at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007346">
        <property type="term" value="P:regulation of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000624">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF107">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 11A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="10"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00041902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00042858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG94202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="325" mass="38028" checksum="C9952B4F911F698F" modified="2017-02-15" version="1">MDNISAERYIFKPNFLGEGSYGRVYKAFDTILKKEVAIKKMKINKISNYIDECGINFVLLREIKIMKEIKHNNIMTALDLYCEKDYINLVMEIMDFDLAKIINRKIFLNDSQKKCILLQILNGLKVLHNYYFMHRDLSPANIFINKKGEVKIADFGLSSKYGFDMYSDMLTKDDKDKKTLNLTNKVVTLWYRAPELLLGSTKYNSSIDMWSFGCIFAELLLQKPLFPGENEIDQLGKIFFLLGTPNENNWPESTYLPLYTEFTKSNKKDFKTIFKNEDDDCIDLLMSFLKLNCHERINAEDALKHKYFFNDPLPCDISQLPFNDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP55</accession>
    <name>A0A1J1GP55_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00178800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000021">
        <property type="protein sequence ID" value="CRG94076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526897.1">
        <property type="nucleotide sequence ID" value="XM_028670113.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP55"/>
    <dbReference type="GeneID" id="39730315"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00178800"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="96" mass="11451" checksum="2E04FCD15B4EAA1D" modified="2017-02-15" version="1">MSYNQNNTTATPAVPLNTTLEDKPLISNNNTYNDSPTNKIIFIFFYIIYIIMTIYTFILFRYAHYRRSRNNNFDLISIDSGYFENFHEDEQEENVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPD1</accession>
    <name>A0A1J1GPD1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dolichyl-phosphate-mannose protein mannosyltransferase, putative</fullName>
            <ecNumber evidence="4">2.4.1.109</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00387000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.109" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526987.1">
        <property type="nucleotide sequence ID" value="XM_028670213.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPD1"/>
    <dbReference type="GeneID" id="39732400"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00387000"/>
    <dbReference type="OMA" id="THMARND"/>
    <dbReference type="OrthoDB" id="5588846at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004169">
        <property type="term" value="F:dolichyl-phosphate-mannose-protein mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23279">
        <property type="entry name" value="beta-trefoil_MIR_SDF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036300">
        <property type="entry name" value="MIR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016093">
        <property type="entry name" value="MIR_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46809:SF2">
        <property type="entry name" value="GH21273P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46809">
        <property type="entry name" value="STROMAL CELL-DERIVED FACTOR 2-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00472">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82109">
        <property type="entry name" value="MIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50919">
        <property type="entry name" value="MIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MIR" evidence="3">
        <location>
            <begin position="66"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="204" mass="23330" checksum="DA6C3D63384E95F5" modified="2017-02-15" version="1" fragment="single">HNCLYVTDGSSIILENIGTKYKLFSTDMKWGTGSGNQLVTAVTTNNNEDDLLWTVSVYEEGKSFTGNKINCDEIVTLKHVKSNGYLISSKHESILSNNYELSVHKNNESGKFQVVCENKKHSSYWEVGKNVFLKSVNHNGYLSTSKSYEFNQYNCHNCPILHHLEACIMKYNYQKDEQKWRAKSGVIITQFNEDTNENYGSDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPJ3</accession>
    <name>A0A1J1GPJ3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00091100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526029.1">
        <property type="nucleotide sequence ID" value="XM_028671677.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPJ3"/>
    <dbReference type="GeneID" id="39729435"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00091100"/>
    <dbReference type="OMA" id="DNTHRSA"/>
    <dbReference type="OrthoDB" id="387564at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052590">
        <property type="entry name" value="Stress/Virulence-Domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36569">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36569:SF4">
        <property type="entry name" value="CYTOPLASMIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="908"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="254"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="941"/>
            <end position="956"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="975" mass="116041" checksum="6D1E83B22FB5325E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPV5</accession>
    <name>A0A1J1GPV5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00194080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000030">
        <property type="protein sequence ID" value="CRG94543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527358.1">
        <property type="nucleotide sequence ID" value="XM_028670624.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPV5"/>
    <dbReference type="GeneID" id="39730466"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00194080"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="86" mass="10131" checksum="7664ADE7D3F50AD2" modified="2017-02-15" version="1" fragment="single">CDSYKTLIYKNILQTKNELNTQLINHLSINTIVKNLNRKLINQALNNIINIVNAKLFLLILVVKIILTLQMNKFIHVFYITKYLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPW9</accession>
    <name>A0A1J1GPW9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00188800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000026">
        <property type="protein sequence ID" value="CRG94493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527311.1">
        <property type="nucleotide sequence ID" value="XM_028670572.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPW9"/>
    <dbReference type="GeneID" id="39730415"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00188800"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013017910" evidence="1">
        <location>
            <begin position="29"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="182" mass="22221" checksum="608651DAE76CE9C6" modified="2017-02-15" version="1">MKTLTLYLKITTFLLLIWMYQCFYNCDSYKTLIDKNIFQTKNKLKYERVLSEDNIPLKKETYSEECLEECSLDNKEKKWENPVKYENPCDQWHKVITPNLWERFNEETSGMDPKLKEKKWNIIWNKISAKKVNDLSLIFRRRDIPDEEKEKLIDSVMEELLLEFEKFLYECKKEMKDNKTES</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ86</accession>
    <name>A0A1J1GQ86_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00182200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527251.1">
        <property type="nucleotide sequence ID" value="XM_028670505.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ86"/>
    <dbReference type="GeneID" id="39730349"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00182200"/>
    <dbReference type="OMA" id="EEFFRCI"/>
    <dbReference type="OrthoDB" id="370883at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="29"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="184"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="315" mass="38029" checksum="9C05F036CCB9CF81" modified="2017-02-15" version="1">MKENISSSNIYINKLHSKNLNDENIDVIIKNEKIINENLTKENEKIKENNLKIQSILLSYIEDNNFIYESDSIEDEKKYKNVLISVIDYIEKLKIVNNQMKNDTYLLLEEFFNCIKEVIIKQNDFCYLIKEDLNYFKISGKEDIFKKNMLTMRKLYEHNSILRSQISLFNKFKLKNENLIHADFEQLELKYKNLKSKENNLEKKIENLNKKIRKSTEKKLHYDEKDLYLEKLLNEKITLLEESYNAIKNKKELLNDLKKKKEESIKKYNEAEINVLTKNVFEGFHEKKQYFNKLKIMMEELKKEYENLSKGERKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQF0</accession>
    <name>A0A1J1GQF0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fam-c protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00192000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000029">
        <property type="protein sequence ID" value="CRG94522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527337.1">
        <property type="nucleotide sequence ID" value="XM_028670601.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQF0"/>
    <dbReference type="GeneID" id="39730445"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00192000"/>
    <dbReference type="OMA" id="HHSKNVE"/>
    <dbReference type="OrthoDB" id="370692at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012927115" description="Fam-c protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="70" mass="8229" checksum="5F6C407DEA833D49" modified="2017-02-15" version="1">MKLSHSGIIFFFFLSCFCLSDNINEKKEKQHLRNTSNIVTIEVLPSDEDENFELYDYLLNEIISINNIDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR05</accession>
    <name>A0A1J1GR05_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TOG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00234200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527758.1">
        <property type="nucleotide sequence ID" value="XM_028671068.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730869"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00234200"/>
    <dbReference type="OMA" id="QQKNYIT"/>
    <dbReference type="OrthoDB" id="377790at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061863">
        <property type="term" value="F:microtubule plus end polymerase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051010">
        <property type="term" value="F:microtubule plus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030951">
        <property type="term" value="P:establishment or maintenance of microtubule cytoskeleton polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046785">
        <property type="term" value="P:microtubule polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007051">
        <property type="term" value="P:spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034085">
        <property type="entry name" value="TOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045110">
        <property type="entry name" value="XMAP215"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12609">
        <property type="entry name" value="MICROTUBULE ASSOCIATED PROTEIN XMAP215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01349">
        <property type="entry name" value="TOG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TOG" evidence="3">
        <location>
            <begin position="463"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="domain" description="TOG" evidence="3">
        <location>
            <begin position="720"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2386"/>
            <end position="2409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2534"/>
            <end position="2560"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2869"/>
            <end position="2891"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2908"/>
            <end position="2941"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2078"/>
            <end position="2105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2386"/>
            <end position="2406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2538"/>
            <end position="2560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2870"/>
            <end position="2891"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2909"/>
            <end position="2923"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2959" mass="348937" checksum="1AF495F5F6434654" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRF6</accession>
    <name>A0A1J1GRF6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Regulator of nonsense transcripts 3B, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">UPF3B</name>
        <name evidence="7" type="ORF">PGAL8A_00239900</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RENT3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527815.1">
        <property type="nucleotide sequence ID" value="XM_028671132.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRF6"/>
    <dbReference type="GeneID" id="39730927"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00239900"/>
    <dbReference type="OMA" id="HGKFFYD"/>
    <dbReference type="OrthoDB" id="18087at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045727">
        <property type="term" value="P:positive regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12455">
        <property type="entry name" value="RRM_like_Smg4_UPF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039722">
        <property type="entry name" value="Upf3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005120">
        <property type="entry name" value="UPF3_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13112:SF0">
        <property type="entry name" value="FI21285P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13112">
        <property type="entry name" value="UPF3 REGULATOR OF NONSENSE TRANSCRIPTS-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03467">
        <property type="entry name" value="Smg4_UPF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0866">Nonsense-mediated mRNA decay</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UPF3" evidence="6">
        <location>
            <begin position="126"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="15"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="288" mass="34188" checksum="AFF3F136C79950DD" modified="2017-02-15" version="1">MYSSKRPYKILQKGKINDDNKKDTNEKKKEDIVCEDSKKYISERKKKEELKYYGKSYRKYNNKNYEENERRKKSSRNYNSGSNYYEKYSKIYTNCNDEKLNNQTSLKKKNDVLVSLLTQAKNDVNKKKIVVRHLPPTLSENHFFDSFSNNLKDELDYYYFVNGKIGKDSSSDIIHSRIYLSFKDDLKTEEFIKSQHGKFFYDINGVRYKAIVSLAPNQTLIQKNKHDGRNNTLESDEYFLKCCEEMNNPIQPLRKDIDYYELINVVNENGAILSPIVVELRDKLKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRP0</accession>
    <name>A0A1J1GRP0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcription activator, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00253800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527946.1">
        <property type="nucleotide sequence ID" value="XM_028671278.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRP0"/>
    <dbReference type="SMR" id="A0A1J1GRP0"/>
    <dbReference type="GeneID" id="39731066"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00253800"/>
    <dbReference type="OMA" id="IYLCADC"/>
    <dbReference type="OrthoDB" id="5585087at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.30:FF:000004">
        <property type="entry name" value="DNA-directed RNA polymerases I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.30">
        <property type="entry name" value="RNA polymerase ii, chain L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006591">
        <property type="entry name" value="RNAP_P/RPABC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039747">
        <property type="entry name" value="RPABC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029040">
        <property type="entry name" value="RPABC4/Spt4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12056">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12056:SF2">
        <property type="entry name" value="GEO11084P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03604">
        <property type="entry name" value="Zn_ribbon_RPAB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00659">
        <property type="entry name" value="RPOLCX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63393">
        <property type="entry name" value="RNA polymerase subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="58" mass="6746" checksum="D0956CC9B9014589" modified="2017-02-15" version="1">MYIREQDEDISTEPVVYICGECGIDTVIPPNASLRCKNCGSKIFFKKRSRRVMQYEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRP5</accession>
    <name>A0A1J1GRP5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">DNA topoisomerase</fullName>
            <ecNumber evidence="4 10">5.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">TOP3</name>
        <name evidence="14" type="ORF">PGAL8A_00258200</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the type IA topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="4 10"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527990.1">
        <property type="nucleotide sequence ID" value="XM_028671327.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRP5"/>
    <dbReference type="GeneID" id="39731110"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00258200"/>
    <dbReference type="OMA" id="VIHNVYS"/>
    <dbReference type="OrthoDB" id="430051at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031422">
        <property type="term" value="C:RecQ family helicase-topoisomerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00186">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03362">
        <property type="entry name" value="TOPRIM_TopoIA_TopoIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.290.10:FF:000003">
        <property type="entry name" value="DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.140:FF:000003">
        <property type="entry name" value="DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.460.10">
        <property type="entry name" value="Topoisomerase I, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.20.10">
        <property type="entry name" value="Topoisomerase I, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.290.10">
        <property type="entry name" value="Topoisomerase I, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000380">
        <property type="entry name" value="Topo_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003601">
        <property type="entry name" value="Topo_IA_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013497">
        <property type="entry name" value="Topo_IA_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013824">
        <property type="entry name" value="Topo_IA_cen_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013825">
        <property type="entry name" value="Topo_IA_cen_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013826">
        <property type="entry name" value="Topo_IA_cen_sub3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023405">
        <property type="entry name" value="Topo_IA_core_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003602">
        <property type="entry name" value="Topo_IA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034144">
        <property type="entry name" value="TOPRIM_TopoIII"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11390:SF21">
        <property type="entry name" value="DNA TOPOISOMERASE 3-ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11390">
        <property type="entry name" value="PROKARYOTIC DNA TOPOISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01131">
        <property type="entry name" value="Topoisom_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00417">
        <property type="entry name" value="PRTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00437">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00436">
        <property type="entry name" value="TOP1Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56712">
        <property type="entry name" value="Prokaryotic type I DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52039">
        <property type="entry name" value="TOPO_IA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 10 14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0799">Topoisomerase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Toprim" evidence="12">
        <location>
            <begin position="5"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Topo IA-type catalytic" evidence="13">
        <location>
            <begin position="167"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="399"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="399"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS52039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG95177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="644" mass="76367" checksum="B34C25A16AC15D0C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRP7</accession>
    <name>A0A1J1GRP7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00234700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527763.1">
        <property type="nucleotide sequence ID" value="XM_028671073.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRP7"/>
    <dbReference type="GeneID" id="39730875"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00234700"/>
    <dbReference type="OMA" id="KNWRIQY"/>
    <dbReference type="OrthoDB" id="429145at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="102" mass="12690" checksum="F340ADBE9F80AF84" modified="2017-02-15" version="1">MLNFYVLRFFFNNFRYENLSKKFIENIIKTGTFCRTMLPIFIPISIYQYIRQIDKERYTEELFYEHSKSDNLKSFYDSSMKNNDKNWRIQYDLYLIDKEVNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRT1</accession>
    <name>A0A1J1GRT1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">tRNA guanosine-2'-O-methyltransferase, putative</fullName>
            <ecNumber evidence="5">2.1.1.34</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00254300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.34" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527951.1">
        <property type="nucleotide sequence ID" value="XM_028671283.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRT1"/>
    <dbReference type="GeneID" id="39731071"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00254300"/>
    <dbReference type="OMA" id="AFNKWSR"/>
    <dbReference type="OrthoDB" id="296065at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043527">
        <property type="term" value="C:tRNA methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141100">
        <property type="term" value="F:tRNA (guanine(18)-2'-O)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000241">
        <property type="entry name" value="RlmKL-like_Mtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059073">
        <property type="entry name" value="TRMT11_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13370">
        <property type="entry name" value="RNA METHYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13370:SF3">
        <property type="entry name" value="TRNA (GUANINE(10)-N2)-METHYLTRANSFERASE HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25904">
        <property type="entry name" value="Tmrp11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01170">
        <property type="entry name" value="UPF0020"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017259">
        <property type="entry name" value="tRNA_mtfrase_TRM11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00507">
        <property type="entry name" value="N12N6MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="tRNA (guanine(10)-N(2))-methyltransferase TRMT11 N-terminal" evidence="4">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal RNA large subunit methyltransferase K/L-like methyltransferase" evidence="3">
        <location>
            <begin position="203"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="456" mass="53428" checksum="C9DEEE7341AC41DE" modified="2017-02-15" version="1">MSYLIWFSSHNRYDNCKISELKSLLEIFGHKRNELWLNEKQNNYEGEVFLKVNITDEELWKNIQSRSILIKGVIDLWSEGISYNDLQKNLITKKYLFERNLRNKKWCFYFHSFGKVINQNDKKKKMDHFKTFFDEYKDIDIINPDVQIALFEEYDKKNSEILKKVYFGKCIVLRKYQNSIYNINSETNEKTKVSWWKKYALNKRPILGPTTTDNELAFIMCNLAKVKKGHIVLDPFVGSGGLLVSCSIFNAICIGNDIDIRLLKGYKLSYLNPHMKHQSNKKNIFQNFLYYNLNMPDILVSDNSKPIWNFFHKPWVDAIVTDPPYGNRATVRISVKNSSNANNKEDNICNDELSETSQVINNYEKKLGKKKTMNNKTITYNCTAAVRDLLNIASHTLVDNGMLVFLLPVQLKTIREEIEILNHSDFYLISYDLQTLTSFSGRLIVSMQRKSRILLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRX5</accession>
    <name>A0A1J1GRX5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00176800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526877.1">
        <property type="nucleotide sequence ID" value="XM_028670091.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRX5"/>
    <dbReference type="GeneID" id="39730295"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00176800"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="547" mass="64651" checksum="9996F38DBA574263" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRY0</accession>
    <name>A0A1J1GRY0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAC-A/B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00150300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526616.1">
        <property type="nucleotide sequence ID" value="XM_028675046.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRY0"/>
    <dbReference type="GeneID" id="39730027"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00150300"/>
    <dbReference type="OMA" id="SQKMIFA"/>
    <dbReference type="OrthoDB" id="3169036at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005854">
        <property type="term" value="C:nascent polypeptide-associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22054">
        <property type="entry name" value="NAC_NACA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14278">
        <property type="entry name" value="UBA_NAC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.70.30:FF:000002">
        <property type="entry name" value="Nascent polypeptide-associated complex (NAC), alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.30">
        <property type="entry name" value="Nascent polypeptide-associated complex domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016641">
        <property type="entry name" value="EGD2/NACA0like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044034">
        <property type="entry name" value="NAC-like_UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038187">
        <property type="entry name" value="NAC_A/B_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002715">
        <property type="entry name" value="Nas_poly-pep-assoc_cplx_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21713">
        <property type="entry name" value="NASCENT POLYPEPTIDE ASSOCIATED COMPLEX ALPHA SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01849">
        <property type="entry name" value="NAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19026">
        <property type="entry name" value="UBA_HYPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015901">
        <property type="entry name" value="NAC_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01407">
        <property type="entry name" value="NAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51151">
        <property type="entry name" value="NAC_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAC-A/B" evidence="2">
        <location>
            <begin position="36"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="183" mass="20650" checksum="EBE22C554DE22E58" modified="2017-02-15" version="1">MQDKINSKEDISSSSSCEENDENKNILNPPNRTKMSKGERRARKMLVKLGLKAVPNVHKVIIKKSQKMVFGVSNVEVYKIEGTDSYVIFGDAKTDDLTNSINNFMPDNLSKDPEVPIETETNFESAEKTEEKVQDLDEEKVDDVSMDDVELIMSQTKCSRDMAIKALRKNNNDLVQSIMELSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS63</accession>
    <name>A0A1J1GS63_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Aurora kinase</fullName>
            <ecNumber evidence="10">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ARK2</name>
        <name evidence="13" type="ORF">PGAL8A_00008600</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="10"/>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528130.1">
        <property type="nucleotide sequence ID" value="XM_028671482.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728608"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00008600"/>
    <dbReference type="OMA" id="IETIGQN"/>
    <dbReference type="OrthoDB" id="377346at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14007">
        <property type="entry name" value="STKc_Aurora"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000934">
        <property type="entry name" value="Serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030616">
        <property type="entry name" value="Aur-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24350">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE IAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 7 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 10 13" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="1417"/>
            <end position="1681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="258"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1274"/>
            <end position="1296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1321"/>
            <end position="1354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="269"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="291"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="309"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="1541"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="1427"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="1446"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="1495"/>
            <end position="1497"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="1570"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="cross-link" description="Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)" evidence="8">
        <location>
            <position position="1543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU367134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG95319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1694" mass="198750" checksum="A875538850E13F34" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSD8</accession>
    <name>A0A1J1GSD8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL22</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">60S ribosomal protein L17</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00262500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uL22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528033.1">
        <property type="nucleotide sequence ID" value="XM_028671374.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSD8"/>
    <dbReference type="GeneID" id="39731154"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00262500"/>
    <dbReference type="OMA" id="NTYETAR"/>
    <dbReference type="OrthoDB" id="10254664at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030684">
        <property type="term" value="C:preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00336">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.470.10:FF:000012">
        <property type="entry name" value="60S ribosomal protein L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.10">
        <property type="entry name" value="Ribosomal protein L22/L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001063">
        <property type="entry name" value="Ribosomal_uL22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005721">
        <property type="entry name" value="Ribosomal_uL22_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036394">
        <property type="entry name" value="Ribosomal_uL22_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01038">
        <property type="entry name" value="uL22_arch_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11593">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11593:SF10">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00237">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54843">
        <property type="entry name" value="Ribosomal protein L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6 7" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="202" mass="23378" checksum="00618025B8A70140" modified="2017-02-15" version="1">MVKYAKKLRDQGKCARGAGIDLRVHFKNTYETARAIRRMKLLEAKKYLNDVIEKKRCVPFRKYNGGVGRTNQAKEFNHTQGRWPVKSCKFLLNVLDNVQANAEARNLEIGKLRLIHVMVNKARPGRRRTYKAHGRINPYMSSPCHIQIIAREITKPAKKSLLSSSEKQKKLPFKITLKKLIKLNISKQNKNKNKNIKKTEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSG8</accession>
    <name>A0A1J1GSG8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Merozoite surface protein 5, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">MSP5</name>
        <name evidence="4" type="ORF">PGAL8A_00017600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528218.1">
        <property type="nucleotide sequence ID" value="XM_028671580.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSG8"/>
    <dbReference type="GeneID" id="39728698"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00017600"/>
    <dbReference type="OrthoDB" id="10060424at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0477">Merozoite</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009618939" evidence="2">
        <location>
            <begin position="20"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="3">
        <location>
            <begin position="343"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="381" mass="41228" checksum="802874D49FF73A79" modified="2017-02-15" version="1">MITTRILLIINFFTFLSLNLRNFSNNSFSNLNQGSNLVCNRFLNETTTGSVEENKDRSPTTDVAEKQADQVSPDASGVSQGEQTLTATNGKTTQLTTQSDPKGPEHTSDPTASSPNPSADAKPPSNEGDGSSGQVTKVETSVPKQENQNGQSQTIAPDKAPEVPSPPSDLSKQTTEVKPPQTEEESGGEVKTGDAATSVSKTQEVEVSEHVQTDVDGHSKGNSSTGDSNNELTNPTNKEKLDGESPELVETPTVIEDDYASVHSEDRIERTIEEDTPRNSHGTEYNNFDNFNRLRKYKLGKNASHMNELKEMEEENEKSCTHNNGGCGDDKICITTANNNIACICKEGYLVGNQCVISQSSSLKPLLSLVIYTIISLIIIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSV4</accession>
    <name>A0A1J1GSV4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-i protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00272600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000043">
        <property type="protein sequence ID" value="CRG95526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528335.1">
        <property type="nucleotide sequence ID" value="XM_028671709.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSV4"/>
    <dbReference type="GeneID" id="39731258"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00272600"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="43"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="107"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="171" mass="21338" checksum="C7916141CBDC1756" modified="2017-02-15" version="1" fragment="single">RNYFPKFKAKHEMRVRLEKILNNYFPKFKAKHEMRVRLQKILNNCNKKMKDDLEKEMQEEKKKMEKDQEKLLKKKKEMEHWEKGVLRHKEEWERTLKEKQVFDESMLKVLEGRKKRITEEGEKWKKRMLIEKMELEKKIQKNKEEGEERMLKVIEKFEEKMLNEKKSGKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSX9</accession>
    <name>A0A1J1GSX9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phospholipase A2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00015900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528201.1">
        <property type="nucleotide sequence ID" value="XM_028671561.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSX9"/>
    <dbReference type="GeneID" id="39728681"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00015900"/>
    <dbReference type="OMA" id="HNPYKLF"/>
    <dbReference type="OrthoDB" id="630895at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047499">
        <property type="term" value="F:calcium-independent phospholipase A2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019369">
        <property type="term" value="P:arachidonate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07199">
        <property type="entry name" value="Pat17_PNPLA8_PNPLA9_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185:SF1">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="3 4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="5">
        <location>
            <begin position="327"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="4">
        <location>
            <begin position="370"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="4">
        <location>
            <begin position="520"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="372"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="668" mass="76996" checksum="EF3369EAAF579EBD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSZ3</accession>
    <name>A0A1J1GSZ3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00281700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528428.1">
        <property type="nucleotide sequence ID" value="XM_028671813.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSZ3"/>
    <dbReference type="GeneID" id="39731350"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00281700"/>
    <dbReference type="OMA" id="ECCHLVI"/>
    <dbReference type="OrthoDB" id="428974at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050266">
        <property type="entry name" value="AB_hydrolase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798:SF33">
        <property type="entry name" value="HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G14860)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43798">
        <property type="entry name" value="MONOACYLGLYCEROL LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="57"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="317" mass="37235" checksum="4BA922D7CFCCEC87" modified="2017-02-15" version="1">MYHSKKIVQEYVTCSEGNTFIIYSQNLLSSESKIKIDSTSIVMENNNTKNYNNENEILLFLHGLNGSSYQFENLFSHLIHSNYKFMSLDLYGHGKSTLLKNLNKYTEKLYIEQIYDVLKKKNIFNSNFVIIGFSMGCIIAAHLSIDNKIKIKKLCLISAAGLAKPKHRFLQFLLKHNIRFCLRVAKKYSHLIVSEDSIKSEYFDYHNNIEDVNKRYLILKENHEKFMETFLKVITGTKIQNSKKYYSAFLKKNHEVLFIYGKDDNITPCIYTLKFLEKHEKYLNNVKVAIFPECSHLVLSEKCNELIKHLIYFLQNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT26</accession>
    <name>A0A1J1GT26_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00390700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527024.1">
        <property type="nucleotide sequence ID" value="XM_028670253.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732437"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00390700"/>
    <dbReference type="OrthoDB" id="385656at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="402"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="439"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="505"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1323" mass="157700" checksum="FF5A3729F5348DEE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT52</accession>
    <name>A0A1J1GT52_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00267400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000036">
        <property type="protein sequence ID" value="CRG95471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528281.1">
        <property type="nucleotide sequence ID" value="XM_028671650.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT52"/>
    <dbReference type="GeneID" id="39731203"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00267400"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="191" mass="22956" checksum="AFF99A84AB547383" modified="2017-02-15" version="1">MKTLILYLKITSFLLLIWMYQCFYNCDSYKTLIDKNRLQIKNELKYERVLAEGDIAGKKQTNAEGCQEECPAENKEKEEKKKISKNPRKLSNPYDLWQKFTSPLLLERFKNEISGKDPKWIEEKWKNEWNKISENKVNELSSIYKRSDISNEEKEKLILDTKTELFKLFMEFVDKCKKEMRDNRTQSKSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTJ2</accession>
    <name>A0A1J1GTJ2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">CUGBP Elav-like family member 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CELF2</name>
        <name evidence="7" type="ORF">PGAL8A_00281400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528425.1">
        <property type="nucleotide sequence ID" value="XM_028671809.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTJ2"/>
    <dbReference type="GeneID" id="39731347"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00281400"/>
    <dbReference type="OMA" id="PWKQYFS"/>
    <dbReference type="OrthoDB" id="267048at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12362">
        <property type="entry name" value="RRM3_CELF1-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000237">
        <property type="entry name" value="CUGBP Elav-like family member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000359">
        <property type="entry name" value="CUGBP Elav-like family member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002343">
        <property type="entry name" value="Hud_Sxl_RNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24012">
        <property type="entry name" value="RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00961">
        <property type="entry name" value="HUDSXLRNA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="48"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="146"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="5">
        <location>
            <begin position="300"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="354"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="245"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="463" mass="53290" checksum="97F447D74E43EFB3" modified="2017-02-15" version="1">MNNINTMSNNTQQYNNEKNESSYGETRINEQCNYQINNPYNPAPSIPVKLFVSSIPKNLTENDIRTIFEEFGGIKDIVFIKDKKPNINRANVFVRMESIFYAQKAIKELHGKKVLNENLGPLIVKFAIGELEKYGVNMNNANENEAKLFVGSLPKDITEEKIRNLFNRYGNVTEIYIMKNSNGVSKRCAFVNYGFKEQGIFAIQNLNGKIAIENAEKPIEVRFAETKNQLQEKQILSRSLMNPLNNNNNNNNNNNNNNNNNTYMQSQQFKNMHVGSFSRYPLHMNYNLQNTANQQRTANNSTQSHWKQYFSKEDGRPYYHNELTGQTQWHKPRKLDQSFMNPLNINELTGPVGANIFIFHIPNEWMQNDLLAAFSPFGNIISAHIATEKDTGRNRGFAFVSYDNVDSAINAVKYMNGFLAHKKKLKVTIKKGEEQYVQALLNQRSKLNNTDNRRNFINTGPHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTM0</accession>
    <name>A0A1J1GTM0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pantothenate kinase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00309000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528686.1">
        <property type="nucleotide sequence ID" value="XM_028672100.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTM0"/>
    <dbReference type="GeneID" id="39731623"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00309000"/>
    <dbReference type="OrthoDB" id="498611at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004594">
        <property type="term" value="F:pantothenate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004567">
        <property type="entry name" value="Type_II_PanK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12280:SF20">
        <property type="entry name" value="4'-PHOSPHOPANTETHEINE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12280">
        <property type="entry name" value="PANTOTHENATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03630">
        <property type="entry name" value="Fumble"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="821" mass="96653" checksum="AF7DFD40755E5115" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU24</accession>
    <name>A0A1J1GU24_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00324300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000051">
        <property type="protein sequence ID" value="CRG96030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528838.1">
        <property type="nucleotide sequence ID" value="XM_028672269.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU24"/>
    <dbReference type="GeneID" id="39731776"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00324300"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="136" mass="16349" checksum="A08100F65B30A075" modified="2017-02-15" version="1">MKTFTLCLKIFTFLILTWIFHCFYNYDSSRSFIDKDTLPIKNKLKDKRLLAEGNISEKNLAHIKERKEHYPSGEKDNRNEKLINLKSMFSMWYNAIYLLMCDLPVIVDYEISSKCKEQMLNFYRSNNSFMMYIEPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU92</accession>
    <name>A0A1J1GU92_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutamate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00302300</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homohexamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 8">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528619.1">
        <property type="nucleotide sequence ID" value="XM_028672025.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU92"/>
    <dbReference type="GeneID" id="39731556"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00302300"/>
    <dbReference type="OMA" id="MIMGWMM"/>
    <dbReference type="OrthoDB" id="6718861at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004354">
        <property type="term" value="F:glutamate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05313">
        <property type="entry name" value="NAD_bind_2_Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.285.10:FF:000001">
        <property type="entry name" value="Glutamate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10860:FF:000002">
        <property type="entry name" value="Glutamate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000030">
        <property type="entry name" value="Glutamate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.285.10">
        <property type="entry name" value="Glutamate Dehydrogenase, chain A, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10860">
        <property type="entry name" value="Leucine Dehydrogenase, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006095">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006097">
        <property type="entry name" value="Glu/Leu/Phe/Val/Trp_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033524">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014362">
        <property type="entry name" value="Glu_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050724">
        <property type="entry name" value="Glu_Leu_Phe_Val_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033922">
        <property type="entry name" value="NAD_bind_Glu_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006929">
        <property type="entry name" value="PRK09414.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43571">
        <property type="entry name" value="NADP-SPECIFIC GLUTAMATE DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43571:SF1">
        <property type="entry name" value="NADP-SPECIFIC GLUTAMATE DEHYDROGENASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02812">
        <property type="entry name" value="ELFV_dehydrog_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000185">
        <property type="entry name" value="Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00082">
        <property type="entry name" value="GLFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00074">
        <property type="entry name" value="GLFV_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013153646" description="Glutamate dehydrogenase" evidence="9">
        <location>
            <begin position="20"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase C-terminal" evidence="10">
        <location>
            <begin position="265"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="442"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="7">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG95811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="510" mass="57194" checksum="B9895FBD5467C341" modified="2017-02-15" version="1">MISYLSIVSFILLISYVNGISKTKYMNYITPGFITNEVNIGSYSKNRGKNKLCSLYNYGYNSTKSLESKIDELHEKVICKNKNEPEFLQAFEEVLLCLKPVFKKDNVYLGVLENIAEPERVIQFRVPWVNDKGEHKVNRGFRVQYSSVLGPYKGGLRFHPTVNLSVIKFLGFEQIFKNSLTTLPMGGGKGGSDFDPKEKSENEILNFCQSFMTNLFRHIGPNTDVPAGDIGVGGKEIGFMFGQYKKLKNAFEGVLTGKNIKWGGSNIRSEATGYGVVYFAENALKDLNDNLRNKRCVVSGSGNVAQYLVEKLIEKGAIVLTMSDSNGYVLEPSGFTKEQLAHIMDLKNNQRKRLKEYLKYSKTAKYFENQKPWDIPCDIVFPCATQNEISEKDAENLIKNKCQMVVEGANMPTHIKAIHKLKQNKIIICPSKAANAGGVAVSGLEMSQNSMRLQWTSEETDKKLQNIMKSIYDQCYNTSKEYLNEPDLVAGANIAGFLKVADSFIEQGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUD6</accession>
    <name>A0A1J1GUD6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Leucine aminopeptidase</fullName>
            <ecNumber evidence="4">3.4.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">M17 leucyl aminopeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PGAL8A_00205400</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-cysteinylglycine + H2O = L-cysteine + glycine</text>
            <dbReference type="Rhea" id="RHEA:28783"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:61694"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal amino acid, Xaa-|-Yaa-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Yaa may be Pro. Amino acid amides and methyl esters are also readily hydrolyzed, but rates on arylamides are exceedingly low.</text>
            <dbReference type="EC" id="3.4.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="12">Homohexamer composed of dimer of trimers. Both the identity and concentration of metal ions available dictate the extent to which oligomerization occurs; Mn(2+) and Co(2+) induces oligomerization, whereas Mg(2+) has no effect, and Zn(2+) causes irreversible protein aggregation in vitro.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.1" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527472.1">
        <property type="nucleotide sequence ID" value="XM_028670750.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUD6"/>
    <dbReference type="GeneID" id="39730581"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00205400"/>
    <dbReference type="OrthoDB" id="412814at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070573">
        <property type="term" value="F:metallodipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00433">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.10:FF:000033">
        <property type="entry name" value="M17 leucyl aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="entry name" value="Leucine Aminopeptidase, subunit E, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00181">
        <property type="entry name" value="Cytosol_peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011356">
        <property type="entry name" value="Leucine_aapep/pepB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000819">
        <property type="entry name" value="Peptidase_M17_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023042">
        <property type="entry name" value="Peptidase_M17_leu_NH2_pept"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963:SF23">
        <property type="entry name" value="CYTOSOL AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963">
        <property type="entry name" value="LEUCINE AMINOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00883">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00481">
        <property type="entry name" value="LAMNOPPTDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="Macro domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00631">
        <property type="entry name" value="CYTOSOL_AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 16" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="10" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Cytosol aminopeptidase" evidence="15">
        <location>
            <begin position="443"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00052872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00064254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00071930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00080098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="CRG94657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="591" mass="66618" checksum="B71CC5C82BD1EFB3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUH3</accession>
    <name>A0A1J1GUH3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Lysine-specific histone demethylase 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00310300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528699.1">
        <property type="nucleotide sequence ID" value="XM_028672114.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731636"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00310300"/>
    <dbReference type="OrthoDB" id="406280at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.660.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050281">
        <property type="entry name" value="Flavin_monoamine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742:SF415">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_56, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742">
        <property type="entry name" value="FLAVIN MONOAMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="7">
        <location>
            <begin position="2442"/>
            <end position="2494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="438"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="494"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="838"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1133"/>
            <end position="1162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1189"/>
            <end position="1249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1479"/>
            <end position="1522"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="257"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="494"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="514"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="542"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="840"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1141"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1192"/>
            <end position="1210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1214"/>
            <end position="1224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1484"/>
            <end position="1512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2548" mass="303244" checksum="99E047BF4857DD12" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUS1</accession>
    <name>A0A1J1GUS1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SET domain protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00342000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529007.1">
        <property type="nucleotide sequence ID" value="XM_028672457.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUS1"/>
    <dbReference type="GeneID" id="39731950"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00342000"/>
    <dbReference type="OMA" id="VYDENVY"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050869">
        <property type="entry name" value="H3K4_H4K5_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197:SF292">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="317"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="754" mass="89885" checksum="A1932FB2E6CE5535" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUY5</accession>
    <name>A0A1J1GUY5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00251400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527925.1">
        <property type="nucleotide sequence ID" value="XM_028671254.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUY5"/>
    <dbReference type="GeneID" id="39731042"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00251400"/>
    <dbReference type="OrthoDB" id="392006at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="368" mass="42306" checksum="AA21F49783FC0E71" modified="2017-02-15" version="1">MLTALCLDKNNLFFSEPYHKIAGEENYQNYELNRVLAEQIYENIKNNFNYIKETQYNLNKNNTYQKDNLQSLLENTELINNKCNKKFGGTGKIYCENSEDNKRNLLNNAEFIKFNNTNITHLKTHNTLKNNKNSIEIHQHIPSLNSENFAKFNSTNKTETLDKKEENMCDPRYNEYPPMNGFGYNHHNTTNGNGFYANTFNKELANLTMQQHNMHGRNNLMFEDGNVPYGLYDQSNFAGTNSLMCGNIPLNEPKMMYRRNGMNEQPYNNYMMANGLGYNYPAYGQQFNPNMKGNMMNGGYMHECHYSNNANSAISKSACGSIIDKDHKKEACRKNISKVKKGDIDINIETSSSNRKGVTIDLNIGMGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUZ4</accession>
    <name>A0A1J1GUZ4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Geranylgeranyl pyrophosphate synthase, putative</fullName>
            <ecNumber evidence="6">2.5.1.29</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">GGPPS</name>
        <name evidence="6" type="ORF">PGAL8A_00355300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.29" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529140.1">
        <property type="nucleotide sequence ID" value="XM_028672604.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUZ4"/>
    <dbReference type="GeneID" id="39732083"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00355300"/>
    <dbReference type="OMA" id="CSWVVNQ"/>
    <dbReference type="OrthoDB" id="10257492at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004337">
        <property type="term" value="F:(2E,6E)-farnesyl diphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004161">
        <property type="term" value="F:dimethylallyltranstransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004311">
        <property type="term" value="F:geranylgeranyl diphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045337">
        <property type="term" value="P:farnesyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039702">
        <property type="entry name" value="FPS1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11525:SF0">
        <property type="entry name" value="FARNESYL PYROPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11525">
        <property type="entry name" value="FARNESYL-PYROPHOSPHATE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01017">
        <property type="entry name" value="Polyprenyl_Transferase_Like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="376" mass="44235" checksum="B25D4FE2B9C0EAFB" modified="2017-02-15" version="1">MEKESKNEDSDSGLAFFRSMYDKYRDSVLSYINDYTLEDDIKHIISKYYKLLFDYNCLGGKNNRGILVILIYEYVKNRDINSSEWEKAACLAWCIEILQASFLVADDIMDKGETRRNKFCWYLLKDVETKNAVNDVLFLYNAIYKLIEIYIRNESCYVDIINSFRDATLKTIIGQHLDTNIFSEKYSDINKNIDINDIDIREQSKINVNMVNFKVYKNIVIHKTAYYSFFLPIVCGMQLAGISIDNLIYKKIEDISILMGEYFQVHDDYLDAFGDTKKTGKVGSDIQNNKLTWPLIKTFELCTEEDKTKIIKNYGKSNIACVKIIDNLYEQYNIKYYYKEYEKEQKEKILIAINNIHHEGIEYVLKYLMEILFTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV92</accession>
    <name>A0A1J1GV92_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosphatidylinositol transfer protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00262100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528029.1">
        <property type="nucleotide sequence ID" value="XM_028671370.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731150"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00262100"/>
    <dbReference type="OMA" id="GMFYSWK"/>
    <dbReference type="OrthoDB" id="18453at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008526">
        <property type="term" value="F:phosphatidylinositol transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.530.20:FF:000028">
        <property type="entry name" value="Phosphatidylinositol transfer protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001666">
        <property type="entry name" value="PI_transfer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055261">
        <property type="entry name" value="PI_transfer_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10658">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL TRANSFER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10658:SF11">
        <property type="entry name" value="VIBRATOR, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02121">
        <property type="entry name" value="IP_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00391">
        <property type="entry name" value="PITRANSFER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="930"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="957"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="3">
        <location>
            <begin position="531"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="407"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="636"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="447"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="665"/>
            <end position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1666" mass="198870" checksum="35E95B244ADFC899" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV97</accession>
    <name>A0A1J1GV97_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00236000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527776.1">
        <property type="nucleotide sequence ID" value="XM_028671090.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV97"/>
    <dbReference type="GeneID" id="39730888"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00236000"/>
    <dbReference type="OMA" id="FYNRMSN"/>
    <dbReference type="OrthoDB" id="368995at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="299"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="390"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="513" mass="61159" checksum="379AA1ACD1100E6E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVB9</accession>
    <name>A0A1J1GVB9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00264700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528053.1">
        <property type="nucleotide sequence ID" value="XM_028671396.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVB9"/>
    <dbReference type="GeneID" id="39731176"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00264700"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="113" mass="13121" checksum="7DBF4FC1A4FB8900" modified="2017-02-15" version="1" fragment="single">MALLYNEGCPNSEEDITKCNVLVCIIRGDKFRTQHCDPAFESLILYYPSNDISNNLAKNIFTFEHSITSNSPQSKVTLLSNNDGEIVFLYQMYPYEHNYSSETYLCRFRDIDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW05</accession>
    <name>A0A1J1GW05_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glideosome-associated protein 50, putative</fullName>
            <ecNumber evidence="5">3.1.3.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">GAP50</name>
        <name evidence="5" type="ORF">PGAL8A_00430800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.2" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529532.1">
        <property type="nucleotide sequence ID" value="XM_028673039.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW05"/>
    <dbReference type="SMR" id="A0A1J1GW05"/>
    <dbReference type="GeneID" id="39732840"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00430800"/>
    <dbReference type="OMA" id="MKEGANM"/>
    <dbReference type="OrthoDB" id="411211at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051558">
        <property type="entry name" value="Metallophosphoesterase_PAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10161">
        <property type="entry name" value="TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10161:SF14">
        <property type="entry name" value="TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="369"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="4">
        <location>
            <begin position="27"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="395" mass="44218" checksum="E4DC26DC0F6FE869" modified="2017-02-15" version="1">MNVCKTVFNVFFVLFFITIYQIQCQLRFASLGDWGKESKSQLLNAKYLKQYIKNERVTFIVSPGSNFLDGVKGLNDPAWKNLYEDVYAEESGNMYMPFFTVLGARDWTGNYTSEVLKGQGIYVEKDGETAIEREGDATEYPKWIIPNYWYHYFTHFTVSTGPSIVKTGHKDMAAAFIFIDTWILSPNFPYKNIHERAWDDLKSQLTVAKKIADFIIVVGDQPIYSSGLSRGNSYLAYYLLPLLKDAQVDLYIAGHDNNMEVIEDNDITHVTCGSGAIASGKPAIKSSNSLFFSNDIGFCLHELNNNGIITKFISSKSGEVIYTHKTNLKTKKGLDKLNSLQYVASLPKVELMDIPASGPMGNKDTFIKIVGTVGLLIGSLIVFIGASSFLSKNMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW58</accession>
    <name>A0A1J1GW58_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-editing substrate-binding complex 6 protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00428200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529506.1">
        <property type="nucleotide sequence ID" value="XM_028673011.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW58"/>
    <dbReference type="GeneID" id="39732814"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00428200"/>
    <dbReference type="OMA" id="SNEGPYD"/>
    <dbReference type="OrthoDB" id="333128at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058917">
        <property type="entry name" value="RESC6_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26188">
        <property type="entry name" value="RESC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA-editing substrate-binding complex 6 protein" evidence="1">
        <location>
            <begin position="398"/>
            <end position="622"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF26188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="682" mass="80788" checksum="7166B9D42860F6E6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW63</accession>
    <name>A0A1J1GW63_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00414500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529369.1">
        <property type="nucleotide sequence ID" value="XM_028672858.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732675"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00414500"/>
    <dbReference type="OMA" id="YDITRIF"/>
    <dbReference type="OrthoDB" id="370895at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1450" mass="175068" checksum="75B5162A8B43D3E3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWA3</accession>
    <name>A0A1J1GWA3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00005800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528104.1">
        <property type="nucleotide sequence ID" value="XM_028671453.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWA3"/>
    <dbReference type="GeneID" id="39728580"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00005800"/>
    <dbReference type="OMA" id="PENKVNW"/>
    <dbReference type="OrthoDB" id="407535at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="280" mass="33818" checksum="7AF667F86A5D4611" modified="2017-02-15" version="1">MTLININKIIKKTFKSEINILKNNNIPNNNLRDIGKRYSTIQRPNLYIEKKNSFFMNYRSLSNSKIFLNKDNDFYEGEHLNRKLGGYGYPMMFIVTYDKPSWQPFWENDCEVIPRDEFGVPASLPPEVSTKIKHTYYVPPQFYTFLKKLGDDSAELKPYMTKLIKGEFTYDDYQEMFYKFAKPLKIYRKKIPIPYRTAEEMAREEEMKWQSSWYTYRQKVLAEYNVTMCLREFILYMTVGLYFAYLWLDALRQYRLDMKLFYLEAPEHKINWVKPRGDLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWB2</accession>
    <name>A0A1J1GWB2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">G2 protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00442400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529646.1">
        <property type="nucleotide sequence ID" value="XM_028673166.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWB2"/>
    <dbReference type="GeneID" id="39732957"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00442400"/>
    <dbReference type="OMA" id="SKCFVYP"/>
    <dbReference type="OrthoDB" id="341684at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="132"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="272" mass="31842" checksum="31FAD04E2497589B" modified="2017-02-15" version="1">MGQVASKEEEIERQNIYASYPGLEQQLDMVFACHDIDKQGKLPYKTVEMILRHFLMQCGFMEYVCRFVDENGRLDLNHVENYLSSKKLVHKLKCCGEIMLTLEEMKALVIIFLKKISDTYIEDQAKWMQNMKVSQEEQGKALEAAMSEYEKNVLFSHALKEQRIFQNNKKLGEWNDTIENAYEAQQEILRQFETKKREKMELISEKNKEIEIAKDYIQKIKEAAVDNRYDNSKCFVYPASSAPCGACTSAGAVLPYRRYKEPRQKKEYSMCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWH4</accession>
    <name>A0A1J1GWH4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HIT-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00424900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529473.1">
        <property type="nucleotide sequence ID" value="XM_028672973.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWH4"/>
    <dbReference type="GeneID" id="39732781"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00424900"/>
    <dbReference type="OMA" id="NCVIKKM"/>
    <dbReference type="OrthoDB" id="18412at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd23024">
        <property type="entry name" value="zf-HIT_ZNHIT2-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007529">
        <property type="entry name" value="Znf_HIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039646">
        <property type="entry name" value="ZNHIT2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15555">
        <property type="entry name" value="ZINC FINGER HIT DOMAIN CONTAINING PROTEIN 2 PROTEIN FON -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15555:SF0">
        <property type="entry name" value="ZINC FINGER HIT DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04438">
        <property type="entry name" value="zf-HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51083">
        <property type="entry name" value="ZF_HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="HIT-type" evidence="3">
        <location>
            <begin position="5"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="106"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="112"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="473" mass="57586" checksum="AABBDFDB31098C73" modified="2017-02-15" version="1">MKKTCEVCKNKIFNYVCPSCDIVYCSLECYKKHNDKCVSNFLENQVNENIKSNKITEFDKKEFKFKLKKFYEENSQNDFLGEYKNINKCKENKEKKKKKKDYYCENNYKENNDDDNEEEEDEEEEEEEEEEEEEEEEDEEEEEEDVEEEEEEEEEDVEEEEEEEEEEEGEEEKKNNDDNCNKGEKYKEDKNINSKNNNVEQTSNYSQKWFISKKRYKVLTELALKDELKLENLNKTEKKQFFSFLKNNDMNQYLDKYEPWWLNCVIKKMNIPNHICCNKNVNENVIFIIIEILYSYCYLLRIYNKYITNKEFCYSLLYLANSLNRFNLPESNILNTINNLFQRILENDDLAREKNVLYNVITDVTKILDLKELILRCLYETKKIFKKEIEKINTKKNQCSNNLNNIKKLTEILQEQKLFGYVNKKIKFLYSYSNYHYEKFSDIKNQLSKFYNEQKNFLKSNDKREIILNKEIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWM4</accession>
    <name>A0A1J1GWM4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00424300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529467.1">
        <property type="nucleotide sequence ID" value="XM_028672967.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWM4"/>
    <dbReference type="GeneID" id="39732775"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00424300"/>
    <dbReference type="OMA" id="NINMEHK"/>
    <dbReference type="OrthoDB" id="386741at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="188" mass="22553" checksum="D6A297D7C696D557" modified="2017-02-15" version="1">MNDTTSCNLSVEKRYEHLKLFFSNITSLIFELKDLMKVHEILIYKAKLEANEKGNFKKNQEELMILKQKFELIRKENDKMENQLKYYKSINDSINSQINHTSDNIQKMKSNIILEEQKKIEMKKHINDLKCKYCRTLKQKQILDDNFLHLTKENKKNYKENKEINSLFKELEIKIESVTSNSENIIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXA6</accession>
    <name>A0A1J1GXA6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00466500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529887.1">
        <property type="nucleotide sequence ID" value="XM_028673435.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXA6"/>
    <dbReference type="GeneID" id="39733198"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00466500"/>
    <dbReference type="OMA" id="FNKFICP"/>
    <dbReference type="OrthoDB" id="6596655at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="300" mass="35009" checksum="56D57121DFFC7367" modified="2017-02-15" version="1">MSELLSIKNLFICSHEKSVDELKSAIEGLIGKNKIENSGDNKNEKKYDMIKDYLDANKNNVLHFAVYGNNFNNVKFIIENTNLINSFNIDEQNSLIISILNKNTEISKYLIDNNIDYNKTDKYKSNALLYSLITQNYEIFNILIEKKNIDININSYEKGNLISICVFEKNIKILKKLLNKNISPSFEKNIFPHPLIFIIYSNDNDLLYLYLTYSLYYYTKNEELYKLNEINFDDKTNKIIIDLENKHIIDSILNDKKYDLTIFKKLLNLKDENGSSLLDICTNNNNNTGRNVLLYYSGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXF6</accession>
    <name>A0A1J1GXF6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00483000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530054.1">
        <property type="nucleotide sequence ID" value="XM_028673619.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXF6"/>
    <dbReference type="GeneID" id="39733363"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00483000"/>
    <dbReference type="OrthoDB" id="374798at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="678"/>
            <end position="699"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="726" mass="86639" checksum="35748C9F411F9706" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXG2</accession>
    <name>A0A1J1GXG2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dynein heavy chain, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00319400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528789.1">
        <property type="nucleotide sequence ID" value="XM_028672215.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731727"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00319400"/>
    <dbReference type="OMA" id="FRSIQTC"/>
    <dbReference type="OrthoDB" id="10251809at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097729">
        <property type="term" value="C:9+2 motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008569">
        <property type="term" value="F:minus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060294">
        <property type="term" value="P:cilium movement involved in cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.180.20">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.720">
        <property type="entry name" value="Region D6 of dynein motor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041658">
        <property type="entry name" value="AAA_lid_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042219">
        <property type="entry name" value="AAA_lid_11_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042228">
        <property type="entry name" value="Dynein_linker_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10676:SF36">
        <property type="entry name" value="DYNEIN HEAVY CHAIN AT 93AB, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10676">
        <property type="entry name" value="DYNEIN HEAVY CHAIN FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18198">
        <property type="entry name" value="AAA_lid_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynein heavy chain AAA lid" evidence="3">
        <location>
            <begin position="4841"/>
            <end position="5011"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3356"/>
            <end position="3497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3525"/>
            <end position="3560"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1542"/>
            <end position="1569"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3670"/>
            <end position="3725"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3843"/>
            <end position="3905"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="4043"/>
            <end position="4098"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="3356"/>
            <end position="3455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="3456"/>
            <end position="3465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="3466"/>
            <end position="3497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="3530"/>
            <end position="3541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="3542"/>
            <end position="3551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="5440" mass="656768" checksum="2F7EC5BDEA59A754" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXH5</accession>
    <name>A0A1J1GXH5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATP synthase mitochondrial F1 complex assembly factor 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00484500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530068.1">
        <property type="nucleotide sequence ID" value="XM_028673635.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXH5"/>
    <dbReference type="GeneID" id="39733378"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00484500"/>
    <dbReference type="OrthoDB" id="381295at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033615">
        <property type="term" value="P:mitochondrial proton-transporting ATP synthase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3580.10">
        <property type="entry name" value="ATP12 ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011419">
        <property type="entry name" value="ATP12_ATP_synth-F1-assembly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023335">
        <property type="entry name" value="ATP12_ortho_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21013:SF10">
        <property type="entry name" value="ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21013">
        <property type="entry name" value="ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 2/ATP12 PROTEIN, MITOCHONDRIAL PRECURSOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160909">
        <property type="entry name" value="ATP12-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="400" mass="47782" checksum="964924C3921DE8B1" modified="2017-02-15" version="1">MKNNTFNNNLFKILKKYSTSYIQFANNKQNIKKFSNLKNIDLRKNSLTKKIEIFIDDKILLTNSKNVFALESFDLCFLIKLELLRNKSEMDILKMPITLFSNNLIDFINISKGNKILKRCNNKENYFLNNVTNNLSDSQNSEYDKINGRIVNEMDTNEKNKSKQDCIIEKNILFSKNTYYENNAYKNNFYQNNLTDTHSNNDKNMDNSNSFETERTLIENKIYENFKNDLIFYSNNEKNLLNTDKKCLENFVCLPNSVNYIENYKINNLYEEESDVFSKFLKMFEQIHEVKLNKAKNFETPVQNKNAQEKVQTLIKNMNDSEIFIFYKCTQILNSFIFTYLFLNNFLNYKEVYRYCNLEYIYQFFKWGYVFDINIIKDSNALLMLSSLRLINNILKKEKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXN4</accession>
    <name>A0A1J1GXN4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tetratricopeptide repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00458000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529803.1">
        <property type="nucleotide sequence ID" value="XM_028673341.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXN4"/>
    <dbReference type="GeneID" id="39733113"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00458000"/>
    <dbReference type="OMA" id="ITIKIYC"/>
    <dbReference type="OrthoDB" id="428342at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21581">
        <property type="entry name" value="D-ALANYL-D-ALANINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21581:SF6">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="178"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="377" mass="45136" checksum="0F49BC8CB5DBF1A5" modified="2017-02-15" version="1">MDEHTLYMYEIEDKITIGNINLNEEINKRAIEYFITAKSYIEKKRLKTCETFITDILNYFKKEPFEYIIFMTIKVYCNLRLHCYRSLTNDLNSLRNLDSDNYKFENFSSKYRKKKGSMIPFLLRLVNCYYPYTLSLYFTSFDRLYLLILHYENIIKMCNEKIENNENCNDVYLRKKNIFFHYIIITCYVLCDLLLKKNYIEQAIQLLKDKILYYDPNHINTISLIGKLSLLIGCFDSAKYSFNLASNLSENKNFNHIKMNYNFLNLYLEEYKIALNEILLIYLNNEEEDNNAVNDYSIYCNNLAITHFYNADLKKSIQTLEKAIMDNYLNTFPSVVRNLNYFYELSKTKNETVNKINDIIKNNLNEDEEILSLIPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXT5</accession>
    <name>A0A1J1GXT5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Radial spoke head protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00331900</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528909.1">
        <property type="nucleotide sequence ID" value="XM_028672348.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXT5"/>
    <dbReference type="GeneID" id="39731849"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00331900"/>
    <dbReference type="OMA" id="LINWAGY"/>
    <dbReference type="OrthoDB" id="272202at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001534">
        <property type="term" value="C:radial spoke"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035082">
        <property type="term" value="P:axoneme assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060294">
        <property type="term" value="P:cilium movement involved in cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006802">
        <property type="entry name" value="Radial_spoke"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13159:SF0">
        <property type="entry name" value="RADIAL SPOKE HEAD 6 HOMOLOG A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13159">
        <property type="entry name" value="RADIAL SPOKEHEAD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04712">
        <property type="entry name" value="Radial_spoke"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0969">Cilium</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="194"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="335"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="337"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="352"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="535" mass="64020" checksum="FD257422688DACA1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXU4</accession>
    <name>A0A1J1GXU4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00485600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530079.1">
        <property type="nucleotide sequence ID" value="XM_028673648.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXU4"/>
    <dbReference type="GeneID" id="39733389"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00485600"/>
    <dbReference type="OMA" id="GNIITHI"/>
    <dbReference type="OrthoDB" id="377352at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1136" mass="136129" checksum="962FBE26B47974B8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY41</accession>
    <name>A0A1J1GY41_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">HORMA domain protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00505500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530283.1">
        <property type="nucleotide sequence ID" value="XM_028673874.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY41"/>
    <dbReference type="GeneID" id="39733588"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00505500"/>
    <dbReference type="OrthoDB" id="1928087at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.900.10">
        <property type="entry name" value="HORMA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003511">
        <property type="entry name" value="HORMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036570">
        <property type="entry name" value="HORMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051294">
        <property type="entry name" value="HORMA_MeioticProgression"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48225">
        <property type="entry name" value="HORMA DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48225:SF7">
        <property type="entry name" value="MEIOSIS-SPECIFIC PROTEIN HOP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02301">
        <property type="entry name" value="HORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56019">
        <property type="entry name" value="The spindle assembly checkpoint protein mad2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50815">
        <property type="entry name" value="HORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0469">Meiosis</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HORMA" evidence="8">
        <location>
            <begin position="15"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="615"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="764"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="281"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="640"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="779"/>
            <end position="791"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG97482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="791" mass="92499" checksum="957229683C3EB0A6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY75</accession>
    <name>A0A1J1GY75_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Helicase ATP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00498500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530214.1">
        <property type="nucleotide sequence ID" value="XM_028673797.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733518"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00498500"/>
    <dbReference type="OMA" id="PMVLEEC"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18042">
        <property type="entry name" value="DEXXQc_SETX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF495">
        <property type="entry name" value="HELICASE SENATAXIN ISOFORM X1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="999"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1068"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="4">
        <location>
            <begin position="1716"/>
            <end position="2089"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="5">
        <location>
            <begin position="2097"/>
            <end position="2357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1295"/>
            <end position="1332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1354"/>
            <end position="1374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2499"/>
            <end position="2528"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1685"/>
            <end position="1712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1354"/>
            <end position="1367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2509"/>
            <end position="2522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2528" mass="302121" checksum="278AC884FCC1D4C9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYK3</accession>
    <name>A0A1J1GYK3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">lipoate--protein ligase</fullName>
            <ecNumber evidence="4">6.3.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">LipL1</name>
        <name evidence="11" type="ORF">PGAL8A_00510900</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-lysyl-[lipoyl-carrier protein] + (R)-lipoate + ATP = N(6)-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein] + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:49288"/>
            <dbReference type="Rhea" id="RHEA-COMP:10500"/>
            <dbReference type="Rhea" id="RHEA-COMP:10502"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.1.20"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein lipoylation via exogenous pathway; protein N(6)-(lipoyl)lysine from lipoate: step 1/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein lipoylation via exogenous pathway; protein N(6)-(lipoyl)lysine from lipoate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the LplA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.20" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530337.1">
        <property type="nucleotide sequence ID" value="XM_028673934.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYK3"/>
    <dbReference type="GeneID" id="39733642"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00510900"/>
    <dbReference type="OMA" id="NENITCE"/>
    <dbReference type="OrthoDB" id="201621at2759"/>
    <dbReference type="UniPathway" id="UPA00537">
        <property type="reaction ID" value="UER00594"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016979">
        <property type="term" value="F:lipoate-protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017118">
        <property type="term" value="F:lipoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16443">
        <property type="entry name" value="LplA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.50">
        <property type="entry name" value="CO dehydrogenase flavoprotein, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019491">
        <property type="entry name" value="Lipoate_protein_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004562">
        <property type="entry name" value="LipoylTrfase_LipoateP_Ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12561">
        <property type="entry name" value="LIPOATE-PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12561:SF3">
        <property type="entry name" value="LIPOYLTRANSFERASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10437">
        <property type="entry name" value="Lip_prot_lig_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21948">
        <property type="entry name" value="LplA-B_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82649">
        <property type="entry name" value="SufE/NifU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="10">
        <location>
            <begin position="59"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="234"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG97536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="410" mass="47573" checksum="CBB96D3121BB2915" modified="2017-02-15" version="1">MKGIFRYLKRCYSNERKNISPIILISNNQNIHFNLSLENFLLNNYNDLLKYLNVNTIEKFNEPVLFLWRNNKSIIIGKNQNIWSECDLNNIKDDGVLVARRFTGGGAVYHDLGNLCFTFLNSTINTSNNFAIILNTLKNHFNINAKAQGRNDITVNDLKCSGSAFKKIKDVFLHHGTIMVNLEKNVLSKYLTPDKIKYIKHGVSSVNARTINLKEVNSNITCENLCVALIKEFIKFYQKDNNNENDILNQLTNENNLINNKSRNEEKDELVDKDGLCNLINNNNMVSDNLNIHYIDKNTNITKNPQFLKFFNLLKDWDWCYGKTPKFQNRLCKRFSFGKVEIFFNVTNGLIKDGNVFSDCLDINLIDQLKSIFNNDVKYSKESIKSFLQNLNVENKNSLEEITMWILEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYQ6</accession>
    <name>A0A1J1GYQ6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00365700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529237.1">
        <property type="nucleotide sequence ID" value="XM_028672712.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732187"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00365700"/>
    <dbReference type="OMA" id="MMRTPKV"/>
    <dbReference type="OrthoDB" id="387139at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="80"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="355"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="555"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1127"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2384"/>
            <end position="2404"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1246"/>
            <end position="1336"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1374"/>
            <end position="1453"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1487"/>
            <end position="1535"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1574"/>
            <end position="1636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="355"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="373"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="397"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="466"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="555"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3247" mass="383860" checksum="7166F51B8424D1FB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYT2</accession>
    <name>A0A1J1GYT2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00338900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528976.1">
        <property type="nucleotide sequence ID" value="XM_028672423.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYT2"/>
    <dbReference type="GeneID" id="39731919"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00338900"/>
    <dbReference type="OMA" id="YMWIFAS"/>
    <dbReference type="OrthoDB" id="379585at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="72" mass="8547" checksum="6FA228DAAE54CDAA" modified="2017-02-15" version="1">MSDKSRRAFLFGVTTVLIFCSFATVESYRYMWIFGSICAFLLLLIDIMFFGADKFNYDPFYSNWEKKNIKDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ26</accession>
    <name>A0A1J1GZ26_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GPR180/TMEM145 transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00528100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530505.1">
        <property type="nucleotide sequence ID" value="XM_028674120.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ26"/>
    <dbReference type="GeneID" id="39733814"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00528100"/>
    <dbReference type="OrthoDB" id="45670at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007186">
        <property type="term" value="P:G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019236">
        <property type="term" value="P:response to pheromone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047831">
        <property type="entry name" value="GPR180/TMEM145"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019336">
        <property type="entry name" value="GPR180/TMEM145_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23252">
        <property type="entry name" value="INTIMAL THICKNESS RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23252:SF24">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 145"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10192">
        <property type="entry name" value="GPR180-TMEM145_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="376"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="415"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="458"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="490"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="523"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="562"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="590"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="domain" description="GPR180/TMEM145 transmembrane" evidence="2">
        <location>
            <begin position="387"/>
            <end position="607"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="643" mass="76819" checksum="F306AB759BC5277F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ50</accession>
    <name>A0A1J1GZ50_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00531000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530534.1">
        <property type="nucleotide sequence ID" value="XM_028674152.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ50"/>
    <dbReference type="GeneID" id="39733843"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00531000"/>
    <dbReference type="OrthoDB" id="372571at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="168"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="212"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="235"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="470"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="507"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="601"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="648"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="345"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="701" mass="84453" checksum="6B28970522EFAC6A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ79</accession>
    <name>A0A1J1GZ79_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00354100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529128.1">
        <property type="nucleotide sequence ID" value="XM_028672591.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ79"/>
    <dbReference type="GeneID" id="39732071"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00354100"/>
    <dbReference type="OMA" id="IFHINLK"/>
    <dbReference type="OrthoDB" id="390845at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011955576" evidence="1">
        <location>
            <begin position="24"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="154" mass="18745" checksum="65117B646FBBA891" modified="2017-02-15" version="1">MSKLKLQIFLYFIFLYGMKFIKPRKVCNVLQFGSYILSSNKENKKYFKYEIVGIIDPFDKNKTLWCRKRRKKFNIHLFKNLYSSLFCNINDYVHLNNSDQFIFRIFQINLKKTIQYMLKYKVVSGKTKKDIEDKEILSLKENSFLFRFLNNINI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZA5</accession>
    <name>A0A1J1GZA5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Vacuolar protein sorting-associated protein 11, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">VPS11</name>
        <name evidence="10" type="ORF">PGAL8A_00023200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530598.1">
        <property type="nucleotide sequence ID" value="XM_028674224.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZA5"/>
    <dbReference type="GeneID" id="39728755"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00023200"/>
    <dbReference type="OMA" id="FNDEHTM"/>
    <dbReference type="OrthoDB" id="26184at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030897">
        <property type="term" value="C:HOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007032">
        <property type="term" value="P:endosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048284">
        <property type="term" value="P:organelle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007033">
        <property type="term" value="P:vacuole organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006904">
        <property type="term" value="P:vesicle docking involved in exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057308">
        <property type="entry name" value="CHCR_PEP5_VPS11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000547">
        <property type="entry name" value="Clathrin_H-chain/VPS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024763">
        <property type="entry name" value="VPS11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23323">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23323:SF24">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23356">
        <property type="entry name" value="TPR_PEP5_VPS11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12451">
        <property type="entry name" value="VPS11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50236">
        <property type="entry name" value="CHCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="repeat" description="CHCR" evidence="8">
        <location>
            <begin position="492"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="967"/>
            <end position="1001"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG97797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1051" mass="126865" checksum="F906A8600C554C88" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZB7</accession>
    <name>A0A1J1GZB7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00515000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530378.1">
        <property type="nucleotide sequence ID" value="XM_028673980.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZB7"/>
    <dbReference type="GeneID" id="39733683"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00515000"/>
    <dbReference type="OMA" id="VHRQNAY"/>
    <dbReference type="OrthoDB" id="360985at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="210"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="398"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="486"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="706" mass="83705" checksum="14FFB71FFA698E5A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZJ4</accession>
    <name>A0A1J1GZJ4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SNAP protein (Soluble N-ethylmaleimide-sensitive factor attachment protein), putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00030100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the SNAP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530665.1">
        <property type="nucleotide sequence ID" value="XM_028674297.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZJ4"/>
    <dbReference type="GeneID" id="39728824"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00030100"/>
    <dbReference type="OMA" id="WSVKEYL"/>
    <dbReference type="OrthoDB" id="9984275at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005483">
        <property type="term" value="F:soluble NSF attachment protein activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035494">
        <property type="term" value="P:SNARE complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15832">
        <property type="entry name" value="SNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000562">
        <property type="entry name" value="SNAP protein (Soluble N-ethylmaleimide-sensitive factor attachment protein)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000744">
        <property type="entry name" value="NSF_attach"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13768:SF8">
        <property type="entry name" value="ALPHA-SOLUBLE NSF ATTACHMENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13768">
        <property type="entry name" value="SOLUBLE NSF ATTACHMENT PROTEIN SNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14938">
        <property type="entry name" value="SNAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00448">
        <property type="entry name" value="NSFATTACHMNT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="298" mass="34771" checksum="97DF0D7441DE7275" modified="2017-02-15" version="1">MEYEAKELEKKAEQLKKKGFFASFFGNDNTDEIINCYNMAANKYKLSHKWKEACSCILKNANLHKKNNETSYCANAYLEAGNIAKKYDKLEAIKYIEESVNLYATLGRFSNCGKCEKNIAEIYEDLCEYDNASKYYKKAAYYFEMDEYSKSVYTQCIVKYAELNSQYNHEYEEAISIFEKEAEKALKSTLLQYGARDYYIKAGILHIVIGDLVNAKISIDKYCMNDPRFLNSREKKFLDDIIEAVTEQNIEYFEEIVHEYDRITKLDNWKVHFLYIIKSKLNVEPNVELTADGGVDLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZP6</accession>
    <name>A0A1J1GZP6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00052900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530891.1">
        <property type="nucleotide sequence ID" value="XM_028674550.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZP6"/>
    <dbReference type="GeneID" id="39729054"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00052900"/>
    <dbReference type="OMA" id="HYLGYKL"/>
    <dbReference type="OrthoDB" id="384318at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="271" mass="32238" checksum="399F9D6AD453591B" modified="2017-02-15" version="1" fragment="single">EEALVIFFSNLFGTFIYISVIKMINRNNVDFHLSNIIVEYIQKKKIHKNRSFLTAFVYPKIPYFLKKIIMKILIFSCPYSHIGNKYIDRVFMNNVELYSSIIMDFYLNEFICSFLSYVLLYIYLFTKDNLSYPIQINLIFTQLIFLFSNDSSHLIGGPFMSLSWIINDCIQKKFKFLFLFFLIVFHYFGYKLAILILKKPHLSLLDATNYYQNIDQDILQDNLTEYGKVDISLIINEHIKDSNVVDSYLGRFFQKVLNLYLFKISNKKKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZS5</accession>
    <name>A0A1J1GZS5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">F-actin-capping protein subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CPbeta</name>
        <name evidence="8" type="ORF">PGAL8A_00039100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Cytoplasm</location>
            <location evidence="1 7">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the F-actin-capping protein beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530753.1">
        <property type="nucleotide sequence ID" value="XM_028674395.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZS5"/>
    <dbReference type="GeneID" id="39728915"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00039100"/>
    <dbReference type="OMA" id="WSNKYYP"/>
    <dbReference type="OrthoDB" id="9979678at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008290">
        <property type="term" value="C:F-actin capping protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051016">
        <property type="term" value="P:barbed-end actin filament capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.210">
        <property type="entry name" value="F-actin capping protein, beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037282">
        <property type="entry name" value="CapZ_alpha/beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042276">
        <property type="entry name" value="CapZ_alpha/beta_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001698">
        <property type="entry name" value="CAPZB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043175">
        <property type="entry name" value="CAPZB_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10619">
        <property type="entry name" value="F-ACTIN-CAPPING PROTEIN SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10619:SF0">
        <property type="entry name" value="F-ACTIN-CAPPING PROTEIN SUBUNIT BETA ISOFORMS 1 AND 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01115">
        <property type="entry name" value="F_actin_cap_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00192">
        <property type="entry name" value="FACTINCAPB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90096">
        <property type="entry name" value="Subunits of heterodimeric actin filament capping protein Capz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0117">Actin capping</keyword>
    <keyword evidence="5 7" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="4 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="301" mass="35169" checksum="2DD700288B8A5A5B" modified="2017-02-15" version="1">MEKTKVEAALSICNILPSHLFEETIKILSEIDQNLTNNILINKEGPIKTKFDSEEKKYYLANMFNKEKDSYRSPYANIYYPDNFSNSYIPSEPLRNLEILFNEIFDKYRKAYYISGLSSVYLWPNPTEEGFVGCFLIKKSESFNVNTSIIWEATHLIQVNISHLIIHYQISSTVNFYITKKNEIILSASINKALENPKKILDMNLLKDKFFHMENMGKMIESIENSLRKSIEYIYMPKITDILNSLRFNDLLCDYAYDEKIIKLKNICNNVTSSKESIQDELKLKFKNKNLNLGTQYSINT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H032</accession>
    <name>A0A1J1H032_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00023700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530602.1">
        <property type="nucleotide sequence ID" value="XM_028674228.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H032"/>
    <dbReference type="GeneID" id="39728760"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00023700"/>
    <dbReference type="OrthoDB" id="385699at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013198755" evidence="2">
        <location>
            <begin position="22"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="460"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="491" mass="60203" checksum="72871D3103AAFD3C" modified="2017-02-15" version="1">MKYIFLLLFQFFIFHLKTKRCNDNYQIFISNILINNVNFLFDKDNYLYELKLNEHSTEISISPLLNIWENYIYKKNSLEYGIFFNENTLEYLDNNEIIKSEELYLKQYYIYIDKKKVNFYDLPYSISLKENEEKAITIFYEKFKKYKFKIKNNKKSSYFYLNDINLINDSSNKHLILDEEFRYNIYFYNAHIEENVKKIKVKGKCHDSQMYVNNNLVFDNFIFSLNENTYNNVLIIECRKYEYFNDFIYKKSNNILENFFKKNWHSKIIYNESNYYTIYKEKKILKNFLNKVKNNYKKIFDNEKIHKNKEINKKNSQYPIQNKILSYNVKNNNNEKNISKIKKVLRKFYFFNIFYNISIKIPNYLYNLIDGNICFLNHNKNIETPSEYICDTFHNKATLYSEISNKLFAFVKVSNQNKIYRIIDKVLNNTINFSSNIYLFLETYNDKKIFKIKLKKDNTLYLYFIIFLLIFLFIVNILIFFYKFCINKRIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0C6</accession>
    <name>A0A1J1H0C6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">CDK-activating kinase assembly factor, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MAT1</name>
        <name evidence="7" type="ORF">PGAL8A_00033600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530698.1">
        <property type="nucleotide sequence ID" value="XM_028674335.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0C6"/>
    <dbReference type="GeneID" id="39728859"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00033600"/>
    <dbReference type="OMA" id="NYDCPVC"/>
    <dbReference type="OrthoDB" id="5963at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005675">
        <property type="term" value="C:transcription factor TFIIH holo complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015877">
        <property type="entry name" value="MAT1_centre"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12683">
        <property type="entry name" value="CDK-ACTIVATING KINASE ASSEMBLY FACTOR MAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12683:SF13">
        <property type="entry name" value="CDK-ACTIVATING KINASE ASSEMBLY FACTOR MAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06391">
        <property type="entry name" value="MAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="6"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="101"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="260" mass="31181" checksum="5191E124B52F1A9D" modified="2017-02-15" version="1">MDEYKCISCFENIYLNSEKNLFFFDICKHKICAECLENHLNKHNKQHCPLCKVTISKKNVVPFDIEERIYANQKNIRSKLIEIFNKKRHNFENTPLYNNYLEKVEDIVYTLTNEYDEKKRKIIEAYIKKYEKENSKLIEENNTLMYENEKKKIHEIVKEEGNLYEIIKHRPIINKSNNETYVHSLIKENPKLFDEIKVTNISESQPQPLNPAFKNDTDIPKRKFFNEEELKKSDYAGGYDTSIVFKRCDTEFNSTIYFNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0D9</accession>
    <name>A0A1J1H0D9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chaperone, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00432900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HscB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529552.1">
        <property type="nucleotide sequence ID" value="XM_028673061.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0D9"/>
    <dbReference type="GeneID" id="39732861"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00432900"/>
    <dbReference type="OMA" id="LMFIERF"/>
    <dbReference type="OrthoDB" id="448954at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001671">
        <property type="term" value="F:ATPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044571">
        <property type="term" value="P:[2Fe-2S] cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051259">
        <property type="term" value="P:protein complex oligomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.20">
        <property type="entry name" value="HscB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004640">
        <property type="entry name" value="HscB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036386">
        <property type="entry name" value="HscB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009073">
        <property type="entry name" value="HscB_oligo_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00714">
        <property type="entry name" value="hscB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14021">
        <property type="entry name" value="IRON-SULFUR CLUSTER CO-CHAPERONE PROTEIN HSCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14021:SF15">
        <property type="entry name" value="IRON-SULFUR CLUSTER CO-CHAPERONE PROTEIN HSCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07743">
        <property type="entry name" value="HSCB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47144">
        <property type="entry name" value="HSC20 (HSCB), C-terminal oligomerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="92"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="247" mass="29572" checksum="85EFAAB0B4559A75" modified="2017-02-15" version="1">MNILKCLSLFGKHNTKKILNYQCSSSKLVKNYFMSKNNEFNNKYGEANSDNIKKIKKVKCYNCHNSIDVDLVPFFCKNCKALINVDVFKIFNIFKLFDLEETYDIDKAFLKKKFNDIQKIYHPDKNSQNTELEKINEVSSYLNNAYRTLLNDVDRALYLMEIQYNYKIPEEENMDDEEFLTEIIKINEEITSSKANIELLTKKYKEMYENYVENIKTYFKEKDFNNILNALKKLKFINRILERLQDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2A9</accession>
    <name>A0A1J1H2A9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GTP-binding translation elongation factor tu family protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00520300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530428.1">
        <property type="nucleotide sequence ID" value="XM_028674035.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2A9"/>
    <dbReference type="GeneID" id="39733736"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00520300"/>
    <dbReference type="OMA" id="INEREYC"/>
    <dbReference type="OrthoDB" id="364892at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03710">
        <property type="entry name" value="BipA_TypA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01891">
        <property type="entry name" value="TypA_BipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.250">
        <property type="entry name" value="bipa protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048876">
        <property type="entry name" value="BipA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047041">
        <property type="entry name" value="BipA_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035651">
        <property type="entry name" value="BipA_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042116">
        <property type="entry name" value="TypA/BipA_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF8">
        <property type="entry name" value="TR-TYPE G DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21018">
        <property type="entry name" value="BipA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="1">
        <location>
            <begin position="104"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="767" mass="87085" checksum="8B09A9C7EEDB3C87" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2D7</accession>
    <name>A0A1J1H2D7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ER membrane protein complex subunit 7 beta-sandwich domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00506700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530295.1">
        <property type="nucleotide sequence ID" value="XM_028673887.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2D7"/>
    <dbReference type="GeneID" id="39733600"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00506700"/>
    <dbReference type="OrthoDB" id="375217at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072546">
        <property type="term" value="C:EMC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1120">
        <property type="entry name" value="Carboxypeptidase-like, regulatory domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019008">
        <property type="entry name" value="Beta_sandwich_EMC7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039163">
        <property type="entry name" value="EMC7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13605">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13605:SF4">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09430">
        <property type="entry name" value="EMC7_beta-sandw"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="ER membrane protein complex subunit 7 beta-sandwich" evidence="7">
        <location>
            <begin position="49"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="205" mass="24382" checksum="EF7F7A916ABFAB06" modified="2017-02-15" version="1">MYKIINENLKFLMTIFVITFICLNLKLSKCKEEYIDLKNNYIEGIIKANSDILLNCTVYLDSENYTKPKNNGKFVFTNVNEGVYNLFVSHPYLEFNRFHVEVKQKMTKNNYKMYIVQAYELLLPFEKNNLMSSNIIFEVKNFYEFLIPKKNFSIFKLLKSPLFLTFLFFLILLCLLPQMQKISESANEENYSQVTYKSDFLESVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2I2</accession>
    <name>A0A1J1H2I2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00511500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530343.1">
        <property type="nucleotide sequence ID" value="XM_028673940.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2I2"/>
    <dbReference type="GeneID" id="39733648"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00511500"/>
    <dbReference type="OMA" id="KYAIFLY"/>
    <dbReference type="OrthoDB" id="419431at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="983" mass="118399" checksum="52FB8FFC23707BC2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2M7</accession>
    <name>A0A1J1H2M7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA topoisomerase (ATP-hydrolyzing)</fullName>
            <ecNumber evidence="4">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">SPO11</name>
        <name evidence="13" type="ORF">PGAL8A_00531700</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the TOP6A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530540.1">
        <property type="nucleotide sequence ID" value="XM_028674159.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2M7"/>
    <dbReference type="GeneID" id="39733850"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00531700"/>
    <dbReference type="OMA" id="CMNIFEI"/>
    <dbReference type="OrthoDB" id="5377392at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000228">
        <property type="term" value="C:nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042138">
        <property type="term" value="P:meiotic DNA double-strand break formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000706">
        <property type="term" value="P:meiotic DNA double-strand break processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00223">
        <property type="entry name" value="TOPRIM_TopoIIB_SPO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1360.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002815">
        <property type="entry name" value="Spo11/TopoVI_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013049">
        <property type="entry name" value="Spo11/TopoVI_A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036078">
        <property type="entry name" value="Spo11/TopoVI_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034136">
        <property type="entry name" value="TOPRIM_Topo6A/Spo11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10848">
        <property type="entry name" value="MEIOTIC RECOMBINATION PROTEIN SPO11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10848:SF0">
        <property type="entry name" value="MEIOTIC RECOMBINATION PROTEIN SPO11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21180">
        <property type="entry name" value="TOP6A-Spo11_Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04406">
        <property type="entry name" value="TP6A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01550">
        <property type="entry name" value="TOP6AFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56726">
        <property type="entry name" value="DNA topoisomerase IV, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52041">
        <property type="entry name" value="TOPO_IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 10 13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Spo11/DNA topoisomerase VI subunit A N-terminal" evidence="11">
        <location>
            <begin position="38"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Topoisomerase 6 subunit A/Spo11 TOPRIM" evidence="12">
        <location>
            <begin position="149"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="10">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF21180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG97739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="330" mass="39058" checksum="64A8118603B3EF1E" modified="2017-02-15" version="1">MHNLDSINLLENYVFDFIFKLLDEKKKKFLSKSRIIEITRLIYTIEIILRNLNENTYTTLRQIFYTNSQLFISQNVSNRIIGKITKIIKKPRELLNIYNSPKGIIRGNILLKEKNLNHWVDCMNIFEIRGHLICPFGVSDIIINQNVKYVLLIEKETIFFKLLQSDFINKYGPSILITAKGFPDINTRQLIFEIHRRNKNLKFFCLTDYDAYGLNIAFTYSSKYESKVYYVDDISNDNLYWLILFTPDEAIKKNVLKKIDLNNLSLKDIRILDNICNNLKKKTNKCHAAEINRWIEYATNMKKDGVKYEIDSVINIEKHINMKIKEFLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H375</accession>
    <name>A0A1J1H375_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ribose-5-phosphate isomerase</fullName>
            <ecNumber evidence="4">5.3.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00022500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14657"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="EC" id="5.3.1.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ribose 5-phosphate isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.6" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530591.1">
        <property type="nucleotide sequence ID" value="XM_028674216.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H375"/>
    <dbReference type="GeneID" id="39728748"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00022500"/>
    <dbReference type="OMA" id="ACHVQEK"/>
    <dbReference type="OrthoDB" id="1555531at2759"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00412"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004751">
        <property type="term" value="F:ribose-5-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009052">
        <property type="term" value="P:pentose-phosphate shunt, non-oxidative branch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01398">
        <property type="entry name" value="RPI_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1360:FF:000001">
        <property type="entry name" value="Ribose-5-phosphate isomerase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050262">
        <property type="entry name" value="Ribose-5P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004788">
        <property type="entry name" value="Ribose5P_isomerase_type_A"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00021">
        <property type="entry name" value="rpiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43748">
        <property type="entry name" value="RIBOSE-5-PHOSPHATE ISOMERASE 3, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43748:SF3">
        <property type="entry name" value="RIBOSE-5-PHOSPHATE ISOMERASE 3, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06026">
        <property type="entry name" value="Rib_5-P_isom_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75445">
        <property type="entry name" value="D-ribose-5-phosphate isomerase (RpiA), lid domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="214" mass="23471" checksum="36A081F97FAF9FF5" modified="2017-02-15" version="1">MTIGLGTGTTVFYALERIDNLIKSGKIKDVVCIPTSVDTEIKAKTFGIPLTTLNKNSKIDVAIDGTDEIDLNLNLVKGRGGALVREKLVANSASVFIIIGDESKLCINGLGTTGAVPIEILTFGYEKIIENLLKISTLQNCTYKLREKNGEIFVTDNKNYIVDFFFTDPIEDLLETCKKIKMTTGVIDHGIFLDMTNIALISKYDGTVLTLNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3U0</accession>
    <name>A0A1J1H3U0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00058600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530948.1">
        <property type="nucleotide sequence ID" value="XM_028674613.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3U0"/>
    <dbReference type="GeneID" id="39729111"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00058600"/>
    <dbReference type="OrthoDB" id="373777at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG98151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="170" mass="20701" checksum="C9218D90CA4C4251" modified="2017-02-15" version="1">MKEHENLERLKKKLNPFFIIFRKDEENELKKYSKKNYFINIIKNCKTSSNHSTDIETNKSNILMINKINNNTMRLFNIFNKYNGKDTLEKRKDFINRNMIKNKEFKYSYNNFLAQTYIYSKYFQNVLNKNVLTNTTNNEKDIDELENEYIIVNKVYTIIQEDTSTFIYIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKX8</accession>
    <name>A0A1J1GKX8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00067600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG92972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525794.1">
        <property type="nucleotide sequence ID" value="XM_028670865.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKX8"/>
    <dbReference type="GeneID" id="39729201"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00067600"/>
    <dbReference type="OrthoDB" id="347521at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="434"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="443"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG92972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="808" mass="96336" checksum="E58516F0A6C19A88" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL21</accession>
    <name>A0A1J1GL21_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acyl-CoA synthetase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00072400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525842.1">
        <property type="nucleotide sequence ID" value="XM_028674845.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL21"/>
    <dbReference type="GeneID" id="39729249"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00072400"/>
    <dbReference type="OMA" id="WYHSIGL"/>
    <dbReference type="OrthoDB" id="1700726at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272:SF33">
        <property type="entry name" value="AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="3">
        <location>
            <begin position="55"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="673" mass="76875" checksum="CADFB30B96C22041" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL56</accession>
    <name>A0A1J1GL56_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Palmitoyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">DHHC7</name>
        <name evidence="10" type="ORF">PGAL8A_00075700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525873.1">
        <property type="nucleotide sequence ID" value="XM_028675189.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL56"/>
    <dbReference type="GeneID" id="39729282"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00075700"/>
    <dbReference type="OMA" id="RRFCKWC"/>
    <dbReference type="OrthoDB" id="9909019at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12246">
        <property type="entry name" value="PALMITOYLTRANSFERASE ZDHHC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="108"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="151"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="297"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="9">
        <location>
            <begin position="208"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="34"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG93051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="402" mass="47501" checksum="60503D91BF31555A" modified="2017-02-15" version="1">MSNVNEEGSKNNNLVDNSKIIIVPNQKESSDNKTKKKKKNKNKKSGNDENRKYSTDKSIINITKNIKDEIKDNLVLDTINNIKNEETNKDQIETSQIVQSNKSKLVRLLPVIFIFILLLGIYLIYIMYHCLPLIYKDYKKVYINYDFKRGLIEIIIFHFFLIMYLINYILSIIIPPGSIPNTEEWAFNDYQENYTDEIEYYLLEKKKSGERRYCKWCCKFKPDRTHHCRVCKTCILKMDHHCPWIYNCVGWNNHKYFMLSLIYCCITSIFVSITMFNSVKDAIKNVKTPFSEMFLLLFGETLNSFLALIITCFLFFHIWLMINAMTTIEFCEKQTNYQNQSYSKYYNKGLWGNFKDVFGDSPFLWFLPIDNRKGDGINFVKGYNRGHSEETTDETLPIKGKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL80</accession>
    <name>A0A1J1GL80_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Prefoldin subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00081700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the prefoldin subunit alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525935.1">
        <property type="nucleotide sequence ID" value="XM_028670632.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL80"/>
    <dbReference type="GeneID" id="39729341"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00081700"/>
    <dbReference type="OMA" id="YNWDVAQ"/>
    <dbReference type="OrthoDB" id="6375174at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007021">
        <property type="term" value="P:tubulin complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23156">
        <property type="entry name" value="Prefoldin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.370:FF:000001">
        <property type="entry name" value="Prefoldin subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016655">
        <property type="entry name" value="PFD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004127">
        <property type="entry name" value="Prefoldin_subunit_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12409">
        <property type="entry name" value="PREFOLDIN SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12409:SF0">
        <property type="entry name" value="PREFOLDIN SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02996">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016396">
        <property type="entry name" value="Prefoldin_subunit_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR016396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="189" mass="22548" checksum="8A39FFA89EC3485B" modified="2017-02-15" version="1">MSFEDLTDNTKSVRNIPGAKFIEHITEFLQNKNEETMLRLAKELLLKYKFMEHTFVTRQMNTEKKIPELKDALRVVNTLYKRKEMGESKNMELYFPLEESLYAKGIIEKTDHILLWLGANVMVEFPFNEAIDLLNHHLDRAINLYEEMDKELLWLHEQISTTEINISRIHNYVEMKKRNKENNITENQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLD2</accession>
    <name>A0A1J1GLD2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00071700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525835.1">
        <property type="nucleotide sequence ID" value="XM_028674767.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLD2"/>
    <dbReference type="GeneID" id="39729242"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00071700"/>
    <dbReference type="OrthoDB" id="380866at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="122" mass="14313" checksum="C93B9CB1990E0C60" modified="2017-02-15" version="1">MDTIENKYNFFNSNVSLLELSYDEDLKVNIINKNSSLVNYYKNKLKNKEIQKVKYFDIDITEDVNEINGAFSSPLKICEENEDNLQLKINRFLLSCNDYTYARKILLNDIHITIHHGSNDTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLN0</accession>
    <name>A0A1J1GLN0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">P-type Ca(2+) transporter</fullName>
            <ecNumber evidence="2">7.2.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">ATP6</name>
        <name evidence="18" type="ORF">PGAL8A_00102400</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.10" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526140.1">
        <property type="nucleotide sequence ID" value="XM_028672910.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLN0"/>
    <dbReference type="GeneID" id="39729549"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00102400"/>
    <dbReference type="OMA" id="PVCSIVF"/>
    <dbReference type="OrthoDB" id="3352408at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005388">
        <property type="term" value="F:P-type calcium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000027">
        <property type="entry name" value="Calcium-transporting ATPase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000037">
        <property type="entry name" value="Calcium-transporting ATPase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000014">
        <property type="entry name" value="Calcium-transporting ATPase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000083">
        <property type="entry name" value="Sodium/potassium-transporting ATPase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42861">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08282">
        <property type="entry name" value="Hydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="18" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="307"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="947"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1056"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1089"/>
            <end position="1109"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="17">
        <location>
            <begin position="7"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="419"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="538"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="546"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00038148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="CRG93318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1129" mass="128156" checksum="CD83FFEABBCD25A2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLS1</accession>
    <name>A0A1J1GLS1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Actin-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ARP1</name>
        <name evidence="6" type="ORF">PGAL8A_00099800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 8">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the actin family. ARP1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526114.1">
        <property type="nucleotide sequence ID" value="XM_028672621.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLS1"/>
    <dbReference type="GeneID" id="39729522"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00099800"/>
    <dbReference type="OMA" id="YTTWTGG"/>
    <dbReference type="OrthoDB" id="5132116at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd10216">
        <property type="entry name" value="ASKHA_NBD_Arp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000188">
        <property type="entry name" value="Actin like 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000007">
        <property type="entry name" value="Actin like 7B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000502">
        <property type="entry name" value="Actin-Related Proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="338" mass="37626" checksum="8988F25975C6FE7D" modified="2017-02-15" version="1">MNEYDNQIYSNQPIIIDNGSGYIKSGFAGDDIPNIVFPSYVGRPKYKRVMAGAVEGNIFVGNKAHPVLLTEAPLNPQKNKEKIAEVFFESFNVPALFISIQAILSLYSCGKTNGTVLDCGDGVCHCVSIYEGYSITNTITRTDVAGRDITTYLGYLLRKNGHLFNTSAEMEIVKNMKENCCYVSFNMNKEKTSSEKSITTLPYILPDGSQILIGSERYRAPEVLFNPSILGLEYLGLSELIVTSITRADMDLRKTLYSHIVLSGGTTLFHGFGDRLLNEIRKFAPKDITIRISAPPERKFSTFIGGSILASLATFKKIWISKQEFDEYGSVILHKKTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM14</accession>
    <name>A0A1J1GM14_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipoate-protein ligase B, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">LipB</name>
        <name evidence="3" type="ORF">PGAL8A_00116800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526284.1">
        <property type="nucleotide sequence ID" value="XM_028674510.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM14"/>
    <dbReference type="GeneID" id="39729693"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00116800"/>
    <dbReference type="OrthoDB" id="19908at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033819">
        <property type="term" value="F:lipoyl(octanoyl) transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020605">
        <property type="entry name" value="Octanoyltransferase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10993:SF7">
        <property type="entry name" value="LIPOYLTRANSFERASE 2, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10993">
        <property type="entry name" value="OCTANOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21948">
        <property type="entry name" value="LplA-B_cat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01313">
        <property type="entry name" value="LIPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012317356" evidence="1">
        <location>
            <begin position="21"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="BPL/LPL catalytic" evidence="2">
        <location>
            <begin position="175"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="429" mass="50518" checksum="4787A3BF1A97EB59" modified="2017-02-15" version="1">MNKILLAIKILLNIIILCYANKCIKIFKNESFSRGKYLSFENHKHNIKKMFIKSNFKVNIKKYNKSKIYLSNEIYVFDFSKKLIDYRLAFELQSFLHQSKIILQNENSLNISNKLELNKLKNFKKNLNKYDFCFILQHTPCYTLGSAADPNDILLDKINYYVEELENIHSNFNSDKIIQFINKHENIKNDLDKCDNYDEKKNYFDDFLYNANKKKIPIYRINRGGKATYHGPGQLVLYFIFNLKNYSSNYSQKGISSNCIYPKKHFATSENKEYHVLNENSKDNTTSIEHLFDLHKTINNFQKIGMETLNKFKIKTHTKDNTIGVFYNNKKIISIGMKIRKYVSMHGMSLNFNINKNFLKFLLSCGMNHNHYTSLHELVEIQKNNNINNNKESYNSTLLEKLTSYSIESLKMIFDAKVKVVDDICSIFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMI1</accession>
    <name>A0A1J1GMI1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00131400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526431.1">
        <property type="nucleotide sequence ID" value="XM_028674840.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMI1"/>
    <dbReference type="GeneID" id="39729839"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00131400"/>
    <dbReference type="OMA" id="TEINNHK"/>
    <dbReference type="OrthoDB" id="387678at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="273"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="412" mass="49421" checksum="24A94DD91FE12B39" modified="2017-02-15" version="1">MKEIALYNNNLNFENINKNESIILSEENFENKLNATNKSNNYKMKSSISFHTASSTASMKSIKKKKKKLNCNENKNNNTDEKLNKNDVNLLRFNDMEKRNLFDENNLSCDNKMTLKCRSLSNNKVVLKKLEYEDNNFNFIFKKTKSFNFQNSLKKKIKNNKNKIIINRLKTIQSEILDFKVDNNIYNEKKEKNIVIDSLITSDENEMKKEGILLQYEKYKHKKKRKKKIKSRLFKKSVCYSNYISPDIINLLNQTKLNLTFYQREADDFLNVIRNLQNIVLIEREKYNELKEMLKYTTEEIEKENNKLYEELNIYKQKYYKLKKLISNIGYGIFFNIDKKEMNYKYNNKDNAYINFEKLYISEDNENQSENEYDYIMVNKKLNFAKDKHDNNKCIKKSKNSNHSSLLNYLDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMR1</accession>
    <name>A0A1J1GMR1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Histone chaperone ASF1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ASF1</name>
        <name evidence="7" type="ORF">PGAL8A_00125600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ASF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526371.1">
        <property type="nucleotide sequence ID" value="XM_028674773.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMR1"/>
    <dbReference type="GeneID" id="39729781"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00125600"/>
    <dbReference type="OrthoDB" id="29755at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006335">
        <property type="term" value="P:DNA replication-dependent chromatin assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006337">
        <property type="term" value="P:nucleosome disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1490:FF:000002">
        <property type="entry name" value="Histone chaperone ASF1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1490">
        <property type="entry name" value="Histone chaperone ASF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006818">
        <property type="entry name" value="ASF1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036747">
        <property type="entry name" value="ASF1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017282">
        <property type="entry name" value="Hist_deposition_Asf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12040">
        <property type="entry name" value="ANTI-SILENCING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12040:SF0">
        <property type="entry name" value="HISTONE CHAPERONE ASF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04729">
        <property type="entry name" value="ASF1_hist_chap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037759">
        <property type="entry name" value="Histone_Asf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101546">
        <property type="entry name" value="ASF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="265" mass="30845" checksum="4061AC89A36EA4AF" modified="2017-02-15" version="1">MSEVNVTKVIVNNPICDILDPFVFTIEFEALNKLEADLEWKIFYISAVNNEGESNQDIELDNIFLGPIERGVMMFDYAVNPPDYKNMDIDSVLGLQAILISANYKEKEFIRIAYYMNAFYKDIELREKPPLIPQYDKICRHIFVENPRIVKFNIGWDSGEKDEFKEFDKENEKIEFFKCTKVKDENECSSNITNQSTQENFNISNNNNGNSYISSNFNINSHNVNNYNQNNFLKNNEQSNDLDKCEIFNANLNGISRITIDNKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMT0</accession>
    <name>A0A1J1GMT0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00134800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526465.1">
        <property type="nucleotide sequence ID" value="XM_028674877.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMT0"/>
    <dbReference type="GeneID" id="39729873"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00134800"/>
    <dbReference type="OMA" id="NYKHKMA"/>
    <dbReference type="OrthoDB" id="390662at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="36"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="111" mass="13714" checksum="0D80D6D83E14A4AC" modified="2017-02-15" version="1">MIIERDNEDNERFKNAINFQKNIFKFEKELIKGKELYKLKQEIINYKHIIETLENENNYLKNKVRYYENKFKKLKNEIQIKDESINYLISENDVINKLNKEISQYIYQKIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMV0</accession>
    <name>A0A1J1GMV0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00148200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526598.1">
        <property type="nucleotide sequence ID" value="XM_028675026.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730006"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00148200"/>
    <dbReference type="OMA" id="RKNGRIW"/>
    <dbReference type="OrthoDB" id="372550at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1580"/>
            <end position="1605"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1612"/>
            <end position="1631"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1673"/>
            <end position="1692"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1765"/>
            <end position="1786"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1792"/>
            <end position="1811"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1949"/>
            <end position="1969"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2042"/>
            <end position="2062"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2083"/>
            <end position="2100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2131"/>
            <end position="2147"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="96"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2204" mass="269658" checksum="E94BA2B2BE047469" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMW6</accession>
    <name>A0A1J1GMW6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">60S ribosomal protein L27a, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00146700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526583.1">
        <property type="nucleotide sequence ID" value="XM_028675009.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMW6"/>
    <dbReference type="GeneID" id="39729991"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00146700"/>
    <dbReference type="OMA" id="WGRVGQH"/>
    <dbReference type="OrthoDB" id="61900at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.100.10.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L27a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.100.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01341">
        <property type="entry name" value="Ribosomal_uL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030878">
        <property type="entry name" value="Ribosomal_uL15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_uL15/eL18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="Ribosomal_uL15/eL18_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001196">
        <property type="entry name" value="Ribosomal_uL15_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11721">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11721:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="Ribosomal proteins L15p and L18e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00475">
        <property type="entry name" value="RIBOSOMAL_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL15/eL18" evidence="6">
        <location>
            <begin position="72"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="148" mass="16785" checksum="AF660E340C35C635" modified="2017-02-15" version="1">MATRFKKNRKKRGHVSAGHGRVGKHRKHPGGRGKAGGLHHMRINFDKYHPGYFGKVGMRHFNLLKNRKYCPTINVDKLWGLLPEEKKKEFCDNKNVAPVIDVTRKGYFKVLGNGKLKHNQPIVVKARYFSSLAEKKIKAVGGQCILVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN37</accession>
    <name>A0A1J1GN37_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RNA-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00157900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526692.1">
        <property type="nucleotide sequence ID" value="XM_028675130.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN37"/>
    <dbReference type="GeneID" id="39730104"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00157900"/>
    <dbReference type="OMA" id="NADNYNA"/>
    <dbReference type="OrthoDB" id="446113at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12344">
        <property type="entry name" value="RRM1_SECp43_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050825">
        <property type="entry name" value="RBM42_RBP45_47-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47640:SF10">
        <property type="entry name" value="TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47640">
        <property type="entry name" value="TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="23"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="131"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="464"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="464"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="474"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="540" mass="63651" checksum="AD029D616C1B2A91" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN66</accession>
    <name>A0A1J1GN66_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Splicing factor subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00162200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the SF3B5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526734.1">
        <property type="nucleotide sequence ID" value="XM_028675176.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN66"/>
    <dbReference type="GeneID" id="39730147"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00162200"/>
    <dbReference type="OMA" id="YDRFNIH"/>
    <dbReference type="OrthoDB" id="274726at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009846">
        <property type="entry name" value="SF3b5/RDS3-10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017089">
        <property type="entry name" value="Splicing_factor_3B_subunit_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20978">
        <property type="entry name" value="SPLICING FACTOR 3B SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20978:SF0">
        <property type="entry name" value="SPLICING FACTOR 3B SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07189">
        <property type="entry name" value="SF3b10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037010">
        <property type="entry name" value="Splicing_factor_3B_subunit_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR037010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="88" mass="10408" checksum="BC47E0490EF02C0B" modified="2017-02-15" version="1">MSTFDRFNIHAQLEHLQSKYQGSGHSDTTRWEWLTNIHRDTLASHVGHYSRLAYFAIVENEPIAKIRYRCLQNISIPVVPKERKELKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNB4</accession>
    <name>A0A1J1GNB4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA helicase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00163900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526751.1">
        <property type="nucleotide sequence ID" value="XM_028675195.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNB4"/>
    <dbReference type="GeneID" id="39730164"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00163900"/>
    <dbReference type="OMA" id="HRIGTTH"/>
    <dbReference type="OrthoDB" id="2801544at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004520">
        <property type="term" value="F:DNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18010">
        <property type="entry name" value="DEXHc_HARP_SMARCAL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046768">
        <property type="entry name" value="ExoX-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45766:SF3">
        <property type="entry name" value="DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45766">
        <property type="entry name" value="DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20600">
        <property type="entry name" value="ExoX-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="288"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="574"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="765"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="769"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="786"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="816"/>
            <end position="832"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="842" mass="98778" checksum="68823B59CEF08DEA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNE7</accession>
    <name>A0A1J1GNE7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00170000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526814.1">
        <property type="nucleotide sequence ID" value="XM_028670020.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730227"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00170000"/>
    <dbReference type="OrthoDB" id="392684at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="371"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="509"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="661"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1514"/>
            <end position="1533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1545"/>
            <end position="1566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1659"/>
            <end position="1696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="433"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="444"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1515"/>
            <end position="1533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1546"/>
            <end position="1561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1659"/>
            <end position="1681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1866" mass="219827" checksum="54C7FB2051755D17" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNG7</accession>
    <name>A0A1J1GNG7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">SNARE associated Golgi protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00172200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526836.1">
        <property type="nucleotide sequence ID" value="XM_028670045.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNG7"/>
    <dbReference type="GeneID" id="39730249"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00172200"/>
    <dbReference type="OMA" id="EIMCVGA"/>
    <dbReference type="OrthoDB" id="166803at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015414">
        <property type="entry name" value="TMEM64"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="VTT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12677">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP38-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12677:SF59">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP38-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="VTT_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="155"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="235"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="284"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="354"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="VTT" evidence="7">
        <location>
            <begin position="227"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="401" mass="46211" checksum="00996F164A5D14FB" modified="2017-02-15" version="1">MKKEMDNLENHNNKKYEYLNNDYDTIYEVDKERELLTKNYNTELDYNYENNLINENDNNLNDYANINDFHYIKNDNKNNMNLEKIKLINDNNKQLEEINKDYDNININFDSNEECSETHYDFENKYNDDKNSESNILIESGDIIPSERSHIRTKVLVAGKIALILFLFLLIIFAFTKFKKFLILMHIVIEWVGKQGSWSIVLFILLFTFLSPLFMSVEIMCIGSGLIFSGVYGKVLGVVIAVFSVAVGYVLGMSLCFFISRYLIHNYIYKKLMVYPIYLAFNQAINSNGLSFVLLIRLSPILPASLVSYILGVTSLKYKDFAIGSVSALPSIFLFVYIGALLQDISNLSELENHWSNLVILFIGFIIGVVAIIYITIITKRRLNNLNIMNTSLSTTNVDIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNH0</accession>
    <name>A0A1J1GNH0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">T-complex protein 1 subunit delta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">CCT4</name>
        <name evidence="11" type="ORF">PGAL8A_00164200</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526754.1">
        <property type="nucleotide sequence ID" value="XM_028675198.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNH0"/>
    <dbReference type="GeneID" id="39730167"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00164200"/>
    <dbReference type="OMA" id="HPAANMI"/>
    <dbReference type="OrthoDB" id="10248520at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03338">
        <property type="entry name" value="TCP1_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000010">
        <property type="entry name" value="T-complex protein 1 subunit delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012717">
        <property type="entry name" value="Chap_CCT_delta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054827">
        <property type="entry name" value="thermosome_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02342">
        <property type="entry name" value="chap_CCT_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041082">
        <property type="entry name" value="thermosome_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG93933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="529" mass="57991" checksum="521B04BEB05C7F8C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNT7</accession>
    <name>A0A1J1GNT7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00382600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526943.1">
        <property type="nucleotide sequence ID" value="XM_028670163.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNT7"/>
    <dbReference type="GeneID" id="39732356"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00382600"/>
    <dbReference type="OrthoDB" id="379527at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="99"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="276" mass="32857" checksum="D789339E7311E5AB" modified="2017-02-15" version="1">MAAFKPYKFIILDKFLKNSNFHTQIISYLELSLLCKEIYISENFSKLNYESICRNKLIYYSDESLIYKLKQNKIIDDKVQQNSSNKNNKFINGNSNYNLGENENNIRREQLEVKESNKKKDIEKENSISSNKYDNIRNKNDLVSFFIYDNNKEEELISLLNLNINYKVDHINILCLNNCNLIVNLLKKKFHFKNRVSIYCPFYIIHDIDKNRNSQEKIKDFFYSIFSDFLPLNYKYIYLSDLIRAIILNSELCQNKSSNSLEVLKFLDIMEIIGKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNU7</accession>
    <name>A0A1J1GNU7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein arginine N-methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">PRMT5</name>
        <name evidence="12" type="ORF">PGAL8A_00167400</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526787.1">
        <property type="nucleotide sequence ID" value="XM_028669991.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNU7"/>
    <dbReference type="GeneID" id="39730200"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00167400"/>
    <dbReference type="OMA" id="IKYAWYE"/>
    <dbReference type="OrthoDB" id="1368803at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016274">
        <property type="term" value="F:protein-arginine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.150">
        <property type="entry name" value="Divalent-metal-dependent TIM barrel enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.160.11">
        <property type="entry name" value="Hnrnp arginine n-methyltransferase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025799">
        <property type="entry name" value="Arg_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007857">
        <property type="entry name" value="Arg_MeTrfase_PRMT5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035075">
        <property type="entry name" value="PRMT5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035248">
        <property type="entry name" value="PRMT5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035247">
        <property type="entry name" value="PRMT5_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10738">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10738:SF0">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05185">
        <property type="entry name" value="PRMT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17286">
        <property type="entry name" value="PRMT5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17285">
        <property type="entry name" value="PRMT5_TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015894">
        <property type="entry name" value="Skb1_MeTrfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51678">
        <property type="entry name" value="SAM_MT_PRMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PRMT5 TIM barrel" evidence="10">
        <location>
            <begin position="62"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="PRMT5 arginine-N-methyltransferase" evidence="9">
        <location>
            <begin position="311"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="PRMT5 oligomerisation" evidence="11">
        <location>
            <begin position="481"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="5">
        <location>
            <position position="448"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="5">
        <location>
            <position position="457"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="346"/>
            <end position="347"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="405"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="432"/>
            <end position="433"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="site" description="Critical for specifying symmetric addition of methyl groups" evidence="7">
        <location>
            <position position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR015894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR015894-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR015894-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR015894-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG93966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="650" mass="76582" checksum="C4A813257FC43582" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNV2</accession>
    <name>A0A1J1GNV2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA2/NAM7 helicase, putative</fullName>
            <ecNumber evidence="4">3.6.4.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00386500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526982.1">
        <property type="nucleotide sequence ID" value="XM_028670207.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732395"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00386500"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18042">
        <property type="entry name" value="DEXXQc_SETX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF495">
        <property type="entry name" value="HELICASE SENATAXIN ISOFORM X1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="2">
        <location>
            <begin position="588"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="2">
        <location>
            <begin position="855"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase helicase" evidence="2">
        <location>
            <begin position="934"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="3">
        <location>
            <begin position="1018"/>
            <end position="1310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1464"/>
            <end position="1534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1637" mass="194617" checksum="1F50B08084E73A86" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP05</accession>
    <name>A0A1J1GP05_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">26S proteasome regulatory subunit 4 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">RPT2</name>
        <name evidence="13" type="ORF">PGAL8A_00384500</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526962.1">
        <property type="nucleotide sequence ID" value="XM_028670184.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP05"/>
    <dbReference type="GeneID" id="39732375"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00384500"/>
    <dbReference type="OMA" id="HDWLLME"/>
    <dbReference type="OrthoDB" id="10255768at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19502">
        <property type="entry name" value="RecA-like_PAN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000030">
        <property type="entry name" value="26S protease regulatory subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000007">
        <property type="entry name" value="26S proteasome regulatory subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000039">
        <property type="entry name" value="26S proteasome regulatory subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032501">
        <property type="entry name" value="Prot_ATP_ID_OB_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16450">
        <property type="entry name" value="Prot_ATP_ID_OB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-0647">Proteasome</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="12">
        <location>
            <begin position="224"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="16"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00068880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG94141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="446" mass="49658" checksum="DCC1726A1513B26D" modified="2017-02-15" version="1">MGNSQGGMNSPYGFLGKKDDKDKGKDKEKKKLESSPPSHIGKRKKKNKGNSGHSKLPNVTPNTKCRLKLLKLERIKDYLLLEEEYITNQEQIKTTDDKNYVKLKIDDLRGSPMSVGTLEEMIDENHGIIATSVGPEYYVNILSFVDKDLLEPGCSVLLNNKTNSVVGILLDEVDPLVSVMKVEKAPLESYADIGGLESQIQEIKEAVELPLTHPELYEDIGIKPPKGVILYGPPGTGKTLLAKAVANETSATFLRVVGSELIQKYLGDGPKLVREMFKVAEDHAPSIVFIDEIDAVGTKRYEATSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIDSLDPALIRPGRIDRKIQLPNPDTKTKRRIFQIHTSKMTMSPDVDLEEFVMSKDELSGADIKAICTEAGLLALRERRMKITQVDLRKARDKALFQKKGNIPEGLYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP39</accession>
    <name>A0A1J1GP39_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Iron-sulfur assembly protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">IscA2</name>
        <name evidence="5" type="ORF">PGAL8A_00393800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; iron-sulfur cluster biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HesB/IscA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527055.1">
        <property type="nucleotide sequence ID" value="XM_028670287.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP39"/>
    <dbReference type="GeneID" id="39732468"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00393800"/>
    <dbReference type="OrthoDB" id="333486at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="entry name" value="HesB-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016092">
        <property type="entry name" value="ATAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000361">
        <property type="entry name" value="ATAP_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050322">
        <property type="entry name" value="Fe-S_cluster_asmbl/transfer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017870">
        <property type="entry name" value="FeS_cluster_insertion_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036199">
        <property type="entry name" value="Gp10_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00049">
        <property type="entry name" value="iron-sulfur cluster assembly accessory protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10072:SF41">
        <property type="entry name" value="IRON-SULFUR CLUSTER ASSEMBLY 1 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10072">
        <property type="entry name" value="IRON-SULFUR CLUSTER ASSEMBLY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01521">
        <property type="entry name" value="Fe-S_biosyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="HesB-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56826">
        <property type="entry name" value="Upper collar protein gp10 (connector protein)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01152">
        <property type="entry name" value="HESB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core" evidence="4">
        <location>
            <begin position="142"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="259" mass="30996" checksum="4B84AA2949605C70" modified="2017-02-15" version="1">MYKNLSKPFKCNLNVKLLIFNNLRNYFYHWNKLKRFLHKSSKKNIFHILNIYNKYELLQKLEKTSKNIENKKEIFETNKNYVKSKYTLNDLNKFVFVNENNKSKEEKINKSESKNNKYPILNDDEIKLEKLLKKRNIKKSIITITEEAKKEIKKIIENNNKENKNNNHVLKLYFITKGCNGLTHSFNFVDKNAINKDDEIIYDDHKTILLVIDNKCVLYVINTILDYYKDDLTEKFIFKNPNITSICPCGTSFHFSKKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPB1</accession>
    <name>A0A1J1GPB1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Abscisic acid G-protein coupled receptor-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00384600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526963.1">
        <property type="nucleotide sequence ID" value="XM_028670185.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPB1"/>
    <dbReference type="GeneID" id="39732376"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00384600"/>
    <dbReference type="OMA" id="YNHIMNF"/>
    <dbReference type="OrthoDB" id="264392at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025969">
        <property type="entry name" value="ABA_GPCR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015672">
        <property type="entry name" value="GPHR/GTG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15948">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR 89-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15948:SF0">
        <property type="entry name" value="GOLGI PH REGULATOR A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12430">
        <property type="entry name" value="ABA_GPCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="244"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="270"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="684"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="728"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="769"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="824"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="domain" description="Abscisic acid G-protein coupled receptor-like" evidence="2">
        <location>
            <begin position="669"/>
            <end position="838"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="847" mass="101701" checksum="AF236B01045F52B7" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPI2</accession>
    <name>A0A1J1GPI2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00403700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527154.1">
        <property type="nucleotide sequence ID" value="XM_028670397.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPI2"/>
    <dbReference type="GeneID" id="39732567"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00403700"/>
    <dbReference type="OMA" id="HRNFVWL"/>
    <dbReference type="OrthoDB" id="390489at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="166" mass="20155" checksum="2E72F950D8A837E9" modified="2017-02-15" version="1">MKKADYFIILKQKIKSFSNWYKESSIGHRNFVWLFIGSFCGYIYGKIEYEKKKKNKGVYGDLIYIDEYIVDNKNIRNFEKNYNKLNIHTFKNKGYEYTKLFKAINWDNSPLSYLQLRLWKNKDCYDEYMKNKDVNKLLDNVKKECKFYSSDKYETIVDDSIVRLIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPN5</accession>
    <name>A0A1J1GPN5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">Adenosylhomocysteinase</fullName>
            <ecNumber evidence="9 13">3.13.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">SAHH</name>
        <name evidence="16" type="ORF">PGAL8A_00068200</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 13">
            <text>S-adenosyl-L-homocysteine + H2O = L-homocysteine + adenosine</text>
            <dbReference type="Rhea" id="RHEA:21708"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="3.13.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12 13">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
        <text evidence="12 13">Binds 1 NAD(+) per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Amino-acid biosynthesis; L-homocysteine biosynthesis; L-homocysteine from S-adenosyl-L-homocysteine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the adenosylhomocysteinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.13.2.1" evidence="9 13"/>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG92978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525800.1">
        <property type="nucleotide sequence ID" value="XM_028671532.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPN5"/>
    <dbReference type="GeneID" id="39729207"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00068200"/>
    <dbReference type="OMA" id="EEYWWAT"/>
    <dbReference type="OrthoDB" id="10007170at2759"/>
    <dbReference type="UniPathway" id="UPA00314">
        <property type="reaction ID" value="UER00076"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004013">
        <property type="term" value="F:adenosylhomocysteinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033353">
        <property type="term" value="P:S-adenosylmethionine cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00401">
        <property type="entry name" value="SAHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1480:FF:000011">
        <property type="entry name" value="Adenosylhomocysteinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000004">
        <property type="entry name" value="Adenosylhomocysteinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1480">
        <property type="entry name" value="Adenosylhomocysteinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00563">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042172">
        <property type="entry name" value="Adenosylhomocyst_ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000043">
        <property type="entry name" value="Adenosylhomocysteinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015878">
        <property type="entry name" value="Ado_hCys_hydrolase_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020082">
        <property type="entry name" value="S-Ado-L-homoCys_hydrolase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00936">
        <property type="entry name" value="ahcY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004005">
        <property type="entry name" value="PRK05476.2-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23420">
        <property type="entry name" value="ADENOSYLHOMOCYSTEINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23420:SF0">
        <property type="entry name" value="ADENOSYLHOMOCYSTEINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05221">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00670">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001109">
        <property type="entry name" value="Ad_hcy_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00996">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00997">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00739">
        <property type="entry name" value="ADOHCYASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 12 13" id="KW-0520">NAD</keyword>
    <keyword evidence="6 13" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S-adenosyl-L-homocysteine hydrolase NAD binding" evidence="15">
        <location>
            <begin position="233"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="199"/>
            <end position="201"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="264"/>
            <end position="269"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="341"/>
            <end position="343"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="389"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="396"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001109-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="CRG92978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="477" mass="53586" checksum="7110D015FE9FA4D1" modified="2017-02-15" version="1">MCENKSKVKDISLAPFGKLQMQISENEMPGIMTIREEFEKKKPLKDAKISGCLHMTVECALLIETLQKLGAKIRWCSCNIYSTVDYAAAAVSTLENVTVFAWKGETLEEYWWCVENSLTWGENEGPDLIVDDGGDATLLVHKGVEYEKLYEEKNILPDPASAKNEEEKCFLNLLKKSILKNPKKWTNISKKIIGVSEETTTGVLRLKKMDKNKELLFPAINVNDSVTKQKYDNVYGCRHSLPDGLMRSTDFLISGKIVVICGYGDVGKGCASSMKGLGARVYVTEIDPICAIQAIMEGFNVVTLDEIVDKGDFFITCTGNVDVIKLEHLLKMKNNAVVGNIGHFDDEIQVNELFNYEGVHIENVKPQVDRVTLPNGNKIIVLAKGRLLNLGCATGHPAFVMSFSFCNQVFAQLNLWENRNNSKYENKVYLLPKELDEKVALYHLKKLNASLTELDDNQCEFLGVSKNGPYKSNEYRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPR0</accession>
    <name>A0A1J1GPR0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Kinesin-19, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00181800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527247.1">
        <property type="nucleotide sequence ID" value="XM_028670501.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730345"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00181800"/>
    <dbReference type="OMA" id="MNFIETH"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968">
        <property type="entry name" value="CENTROMERE PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968:SF36">
        <property type="entry name" value="KINESIN HEAVY CHAIN ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0493">Microtubule</keyword>
    <keyword evidence="3 4" id="KW-0505">Motor protein</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="7">
        <location>
            <begin position="239"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="980"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1159"/>
            <end position="1191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1620"/>
            <end position="1644"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="142"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1027"/>
            <end position="1064"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1937"/>
            <end position="1964"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="980"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1161"/>
            <end position="1170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1171"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1634"/>
            <end position="1644"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="321"/>
            <end position="328"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2210" mass="261486" checksum="1A6864EB0DC0A9A6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPR8</accession>
    <name>A0A1J1GPR8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00071400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525832.1">
        <property type="nucleotide sequence ID" value="XM_028674734.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPR8"/>
    <dbReference type="GeneID" id="39729239"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00071400"/>
    <dbReference type="OrthoDB" id="371538at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="153" mass="18028" checksum="793A2E1CE2046F85" modified="2017-02-15" version="1">MCIFFFLNKVLATVGGVLLVFYDLSKIYIPYMQSDYHRSILQDTKYFPSSYFILLSFSYMFLNTLSSTKNYVSNSLRGFLGCFLITYSLFYFLCQSLICYDYSNSELPEFKEAVYFCIFLFLYMCSLIIETFRSLKTKHQINEKESGSIKIEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPT4</accession>
    <name>A0A1J1GPT4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00191600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000028">
        <property type="protein sequence ID" value="CRG94518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527334.1">
        <property type="nucleotide sequence ID" value="XM_028670597.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPT4"/>
    <dbReference type="GeneID" id="39730441"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00191600"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="92" mass="10630" checksum="96F01144C856338E" modified="2017-02-15" version="1">MSDNQSNTIATLTVPFNSSLEDKSPNLFNITYNSNNTISILFITLFIICIIVTLFIGILYQSIQVHYRVHRNNRFDLISIDSGYFENFDEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPU3</accession>
    <name>A0A1J1GPU3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Methionine aminopeptidase</fullName>
            <ecNumber evidence="6">3.4.11.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">METAP1a</name>
        <name evidence="8" type="ORF">PGAL8A_00074600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="5">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="5">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525864.1">
        <property type="nucleotide sequence ID" value="XM_028675089.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPU3"/>
    <dbReference type="GeneID" id="39729271"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00074600"/>
    <dbReference type="OMA" id="HWEHSVA"/>
    <dbReference type="OrthoDB" id="3209743at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004239">
        <property type="term" value="F:initiator methionyl aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01086">
        <property type="entry name" value="MetAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="entry name" value="Creatinase/methionine aminopeptidase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01974">
        <property type="entry name" value="MetAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002467">
        <property type="entry name" value="Pept_M24A_MAP1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00500">
        <property type="entry name" value="met_pdase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43330">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43330:SF7">
        <property type="entry name" value="METHIONINE AMINOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="Creatinase/aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5 6" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5 6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M24" evidence="7">
        <location>
            <begin position="90"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="281"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="329" mass="37229" checksum="02DD2D49E98ACC56" modified="2017-02-15" version="1">MSYLNKSLMFKFLNKIKKKSNIHTHILTPKLSKIKVNESSLFKPTLEDGKYEITKTQEVPGHINCPNYSKTGIVENCNISYEIKDEENIKKMKKAGKLAAECLKLCLENSKKGVTTDYIDKLAFDFIIKNNAYPAGINFHGFPKTLCASPNEVVCHGIPNLRKLKSGDIITYDCTVFLDGVFGDCAGTVAIGEVSENHKKLIDVSKECLYKAISICRDGQKFSEIGRVITEHAQKNGFNVIRDFCGHFIGRNMHMYPLIEHHYPNSHNNDCMKKGQIFTIEPILSEGSINIHTWKDQWTVCTNDNSFCSQWEHTILVLQNSAEILTLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPW1</accession>
    <name>A0A1J1GPW1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00188000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000026">
        <property type="protein sequence ID" value="CRG94485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527303.1">
        <property type="nucleotide sequence ID" value="XM_028670563.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPW1"/>
    <dbReference type="GeneID" id="39730407"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00188000"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="263" mass="31406" checksum="8C222B821587DE8F" modified="2017-02-15" version="1">MKTLTLYLKITIFLLLIWMFQCFYNYDSYKTLIDKNIFQTKNELKYERALAEGDIAGKEQTNAAGCLEECSLDNKKNECKSPVQYENPCDEWHNVISPFLRKQFDEEAREMDPKWRDQKWNNEWNEISANKVSDLSSIYHQQDISEEEKKKKIDSVKKDLYKLFINFLDKFKKEMIDNKTESEYMKETIDNKKESESMKEMIENKNESESNEETIDNKTESESMKETIDNKTESESKNENGKNKIKNKKSNILKFLFKMFDNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ46</accession>
    <name>A0A1J1GQ46_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Early transcribed membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ETRAMP</name>
        <name evidence="3" type="ORF">PGAL8A_00195000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527370.1">
        <property type="nucleotide sequence ID" value="XM_028670637.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ46"/>
    <dbReference type="GeneID" id="39730477"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00195000"/>
    <dbReference type="OrthoDB" id="386258at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006389">
        <property type="entry name" value="Early_transc_mb_plasmodium"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01495">
        <property type="entry name" value="ETRAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09716">
        <property type="entry name" value="ETRAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012068586" evidence="2">
        <location>
            <begin position="25"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="178" mass="20841" checksum="775C2C00A8E69E04" modified="2017-02-15" version="1">MKITKVYFCFIYLLIINLLKQCLCENYLYEKDNYNLADPFANILEEKKKKKRKILYALIGTAITLAGIAALGIGIHESKRKSIWDTQLAVISDDILKSAIAKGIENSKEIYRRGIHDINKILPSIKDIKEYMREEIKRKDLKFTRSQMKEFDSMSRYALYSIKYAMETYKKGCELEML</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQB4</accession>
    <name>A0A1J1GQB4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Serine/threonine protein kinase, putative</fullName>
            <ecNumber evidence="8">2.7.11.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ATG1</name>
        <name evidence="8" type="ORF">PGAL8A_00209200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.17" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527510.1">
        <property type="nucleotide sequence ID" value="XM_028670793.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQB4"/>
    <dbReference type="GeneID" id="39730619"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00209200"/>
    <dbReference type="OMA" id="CAHSDAR"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004683">
        <property type="term" value="F:calcium/calmodulin-dependent protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="42"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="10"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="376" mass="43677" checksum="9D71C2693BFCA5B0" modified="2017-02-15" version="1">MGTTISKRKSNSDKNSKNKSSEKKKQKKKEENDSNIEFIKKYKIINKIGDGNFSKVFCCRGDNKKKCAMKLMCCPLKKTAHYNCFKRELFIMKTLNNKYPYIVKILDYHEKIWKKYYIVKLILEYCEGGSLFEFIKINGSCAHSDARIIIIKLTKAIQYINSLKIMHRDIKPENILLRTKDNVKSVVLSDFGLAKITPSNQTVVKSRSVCGSDFYLAPEIIKNKEYGIKIDIWSLGVLIFFIVTGKVPFTGRNANELYNNILKANIPELLSKEKSLNVQPGLKNLLENILVHDPDKRFSCSDILNHRWIRGTLSSYEFKIFNSSSSLKRLKLDKKRNSYDENDKNDKTKDKTCENEKESFALMKKKYNFFLKKITN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQJ0</accession>
    <name>A0A1J1GQJ0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00125800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526373.1">
        <property type="nucleotide sequence ID" value="XM_028674775.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729783"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00125800"/>
    <dbReference type="OrthoDB" id="392882at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1344" mass="158422" checksum="11EEE2E72EE42A87" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQQ3</accession>
    <name>A0A1J1GQQ3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cation/H+ antiporter, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00132000</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526437.1">
        <property type="nucleotide sequence ID" value="XM_028674847.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQQ3"/>
    <dbReference type="GeneID" id="39729845"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00132000"/>
    <dbReference type="OMA" id="WNPFRHV"/>
    <dbReference type="OrthoDB" id="1699231at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015369">
        <property type="term" value="F:calcium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004713">
        <property type="entry name" value="CaH_exchang"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004798">
        <property type="entry name" value="CAX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00846">
        <property type="entry name" value="caca2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00378">
        <property type="entry name" value="cax"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503:SF22">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0050">Antiport</keyword>
    <keyword evidence="5 9" id="KW-0106">Calcium</keyword>
    <keyword evidence="3 9" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="7 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="254"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="288"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="328"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="363"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="390"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="418"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="10">
        <location>
            <begin position="117"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="10">
        <location>
            <begin position="295"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG93615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="440" mass="48666" checksum="42F0FAAAD29D5080" modified="2017-02-15" version="1">MVMGRVRATSYVRRTISQPLNKNVPPTKKFKNSNVLNDTNLIRNRNLHLQLLCNNVPPDVYDEDISKNYDFEEIGSFYMPRKSDMIGLYNMLNTKLNIFLIFVPIGILSSFLGCKDIYIFFYNFMALIPLSALMGNITEDLALHTGEIIGGLLNATFGNLMEMIFSIQALNAGLINVVQGTLLGSILSNLLLVLGMSFFAGGLYHHVQKFNEKGATCSTSLLLLSSLAITMPTVSSITTNNNSEIILKVSRITAVLIFLTYCLFLLFQLYTHITLFQDKEMTEEIPQLSVVSGSLFLILVTLLVSIHSEYLVNTIESVIKYYNISENFIGVILLPIVGNATEHLTAVTVAIKNKVDLTMGVAVGSSAQIALFVVPVTVLFGWILNKPMTLAFSPLSTVILVISVIVTMAIVQDGESNWLEGVLLISAYLIVSVVFWFDTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQT4</accession>
    <name>A0A1J1GQT4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA-directed RNA polymerase III subunit RPC5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00218100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527599.1">
        <property type="nucleotide sequence ID" value="XM_028670892.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQT4"/>
    <dbReference type="GeneID" id="39730708"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00218100"/>
    <dbReference type="OMA" id="IFKQVEP"/>
    <dbReference type="OrthoDB" id="340681at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006886">
        <property type="entry name" value="RNA_pol_III_Rpc5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12069:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12069">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES III 80 KDA POLYPEPTIDE RNA POLYMERASE III SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04801">
        <property type="entry name" value="RPC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="678" mass="80818" checksum="DEE8C22196F6D41E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQW0</accession>
    <name>A0A1J1GQW0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00232300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527740.1">
        <property type="nucleotide sequence ID" value="XM_028671048.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQW0"/>
    <dbReference type="GeneID" id="39730850"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00232300"/>
    <dbReference type="OMA" id="DAYWVIT"/>
    <dbReference type="OrthoDB" id="375407at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="1">
        <location>
            <begin position="241"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="341" mass="40907" checksum="0E30FB28F5A0F423" modified="2017-02-15" version="1">MLHLLKKIYIIFSILFFFQWDVINSLNFHFKVREYNTKIVSDYFYLNKKLFNNYLFLKTFKKKKFLLKTKKIKSTNENEEDNLGIEIEDLIKNIEKGNYGEDSLKLYKEIENNSKLKEEEEKKIIEKYEKKMNIYNVDDVIKNTDDKLKKCVRSAFSSTSKSETEDPYIKKEHNIMNKIGETFDEIIDDDYPEEELNISNIYKKVNSTKDNNSDSPFKNAAKTLLKYKGLLRMPFEKCPLLNNSYFHWRESMNYIECYIPIFQGTVNKDILFYFKNDYIKLEILKGSDKILLLDHKLCGKINYADTYWVITNDYIVNEKHINLIMPKLGNYLYIWEKLLQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR52</accession>
    <name>A0A1J1GR52_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00216700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527585.1">
        <property type="nucleotide sequence ID" value="XM_028670876.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730694"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00216700"/>
    <dbReference type="OMA" id="ILTHVYY"/>
    <dbReference type="OrthoDB" id="377511at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1361"/>
            <end position="1380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1883"/>
            <end position="1901"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2087"/>
            <end position="2105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2125"/>
            <end position="2141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2335"/>
            <end position="2353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2359"/>
            <end position="2379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2748"/>
            <end position="2770"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2776"/>
            <end position="2796"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="879"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="879"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="893"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="911"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="960"/>
            <end position="970"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2905" mass="352361" checksum="BEB5745617C7EFD1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR61</accession>
    <name>A0A1J1GR61_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Nicotinate-nucleotide adenylyltransferase, putative</fullName>
            <ecNumber evidence="9">2.7.7.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">NMNAT</name>
        <name evidence="9" type="ORF">PGAL8A_00239800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; NAD(+) biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.18" evidence="9"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527814.1">
        <property type="nucleotide sequence ID" value="XM_028671131.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR61"/>
    <dbReference type="SMR" id="A0A1J1GR61"/>
    <dbReference type="GeneID" id="39730926"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00239800"/>
    <dbReference type="OMA" id="IDEIWVV"/>
    <dbReference type="OrthoDB" id="422187at2759"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004515">
        <property type="term" value="F:nicotinate-nucleotide adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD+ biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd02165">
        <property type="entry name" value="NMNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00244">
        <property type="entry name" value="NaMN_adenylyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005248">
        <property type="entry name" value="NadD/NMNAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39321">
        <property type="entry name" value="NICOTINATE-NUCLEOTIDE ADENYLYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39321:SF3">
        <property type="entry name" value="PHOSPHOPANTETHEINE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cytidyltransferase-like" evidence="8">
        <location>
            <begin position="7"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG95001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="205" mass="24639" checksum="4F4D4D651401B840" modified="2017-02-15" version="1">MNKNICIYGGSFDPITRAHEMVLNEISNLNWIDEIWVVISKCRNDKELTDFQHRYKMFSLIINNASQILKNKIFLKDIEYINRTTPTYDLLKMQKEKYPNNTFYFCLGSDLLNDIILWDNGEKLILENYFIIIERGNFKIDKNILKQFPKYYLIEFKQLSEVNFISSSNIRKILTKNDNSNELKKLINPLILNYIKKYNLYRYNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRD9</accession>
    <name>A0A1J1GRD9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyltransferase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00238300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the trehalose phosphatase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the glycosyltransferase 20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527799.1">
        <property type="nucleotide sequence ID" value="XM_028671115.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRD9"/>
    <dbReference type="GeneID" id="39730911"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00238300"/>
    <dbReference type="OMA" id="IFHNIVD"/>
    <dbReference type="OrthoDB" id="755951at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001070">
        <property type="term" value="F:starch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004805">
        <property type="term" value="F:trehalose-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005992">
        <property type="term" value="P:trehalose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05467">
        <property type="entry name" value="CBM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000052">
        <property type="entry name" value="Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013784">
        <property type="entry name" value="Carb-bd-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002044">
        <property type="entry name" value="CBM20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001830">
        <property type="entry name" value="Glyco_trans_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003337">
        <property type="entry name" value="Trehalose_PPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00685">
        <property type="entry name" value="T6PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788:SF94">
        <property type="entry name" value="ALPHA,ALPHA-TREHALOSE-PHOSPHATE SYNTHASE [UDP-FORMING] 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788">
        <property type="entry name" value="TREHALOSE-6-PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00686">
        <property type="entry name" value="CBM_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00982">
        <property type="entry name" value="Glyco_transf_20"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02358">
        <property type="entry name" value="Trehalose_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01065">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49452">
        <property type="entry name" value="Starch-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51166">
        <property type="entry name" value="CBM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBM20" evidence="3">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1171" mass="137726" checksum="F58F2FAAD900C609" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRN9</accession>
    <name>A0A1J1GRN9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytidine and deoxycytidylate deaminase, putative</fullName>
            <ecNumber evidence="3">3.5.4.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00260400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.5" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528012.1">
        <property type="nucleotide sequence ID" value="XM_028671351.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRN9"/>
    <dbReference type="GeneID" id="39731133"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00260400"/>
    <dbReference type="OMA" id="YQERNEN"/>
    <dbReference type="OrthoDB" id="1701769at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004126">
        <property type="term" value="F:cytidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052717">
        <property type="term" value="F:tRNA-specific adenosine-34 deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002100">
        <property type="term" value="P:tRNA wobble adenosine to inosine editing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079">
        <property type="entry name" value="CYTOSINE DEAMINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079:SF149">
        <property type="entry name" value="TRNA-SPECIFIC ADENOSINE DEAMINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="2">
        <location>
            <begin position="8"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="193" mass="23276" checksum="DA9F5B55D815EB29" modified="2017-02-15" version="1" fragment="single">MVQLNEEEATYFLNIALREAEKSLHIELKEMPIFCLIINEEKKIISSSYNQTNESKNGCRHCELIAIDKYIYNENYEQLKNFNFIKCFNNKDNYIEDSLCNYMNESYNNKKIKDINLYYKYQERNENEVFEKNINETHNKNNKNEKYNENYKVILNYDEKKNEIQEKLNNLKKCCIIVTCEPCIMCVYALKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRV8</accession>
    <name>A0A1J1GRV8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00241200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527827.1">
        <property type="nucleotide sequence ID" value="XM_028671146.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRV8"/>
    <dbReference type="GeneID" id="39730940"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00241200"/>
    <dbReference type="OMA" id="VDCLYLV"/>
    <dbReference type="OrthoDB" id="336240at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09212">
        <property type="entry name" value="PUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036339">
        <property type="entry name" value="PUB-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143503">
        <property type="entry name" value="PUG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="86"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="239"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="378" mass="46086" checksum="EF356CC66905E190" modified="2017-02-15" version="1">MTDYKIAVSSIEEIKDICSELLNSKEEDIYNKLSLYYEFEDKLKKLQPIITRIRIRRNETNEEKKIYGEKMIKNVDVLLERYDMLYNIYEEELTVFKENYEIEKNKKIEKRLLEEQKKKEYEQETLNRGRIKTKMEEEEIIKKNEEKLRILKEEKEENEKKIKKMEIIKAVIQEKCNFLYDEISNACSKKEAIKYIYSQLGVNNKNYNDIEDDNRLCNFSYFIDCLYLVYKNNEYKLFKEAIRNIIEYLEELVKNIDNEQLKLINLMNKTFQNNILSKKGTLFMFILIGYVLKRPEEITQILKKINREINKENIYIYLEEPNIINGYKEWKIWFENIQMSLNILCTFFRHVNKYSDIPDDEKIKSIFLYLREKFGNEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS13</accession>
    <name>A0A1J1GS13_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Spindle pole body protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00002800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TUBGCP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528074.1">
        <property type="nucleotide sequence ID" value="XM_028671419.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728550"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00002800"/>
    <dbReference type="OMA" id="HNTIKHY"/>
    <dbReference type="OrthoDB" id="2192946at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000930">
        <property type="term" value="C:gamma-tubulin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043015">
        <property type="term" value="F:gamma-tubulin binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051011">
        <property type="term" value="F:microtubule minus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051225">
        <property type="term" value="P:spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1900">
        <property type="entry name" value="Gamma-tubulin complex, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007259">
        <property type="entry name" value="GCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040457">
        <property type="entry name" value="GCP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042241">
        <property type="entry name" value="GCP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041470">
        <property type="entry name" value="GCP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302:SF14">
        <property type="entry name" value="GAMMA-TUBULIN COMPLEX COMPONENT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04130">
        <property type="entry name" value="GCP_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17681">
        <property type="entry name" value="GCP_N_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma tubulin complex component protein N-terminal" evidence="8">
        <location>
            <begin position="624"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="domain" description="Gamma tubulin complex component C-terminal" evidence="7">
        <location>
            <begin position="1241"/>
            <end position="1527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="551"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1138"/>
            <end position="1212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="551"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1141"/>
            <end position="1160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1161"/>
            <end position="1179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1180"/>
            <end position="1191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1201"/>
            <end position="1212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG95263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1787" mass="214572" checksum="ED487AE3D4D3BF74" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS28</accession>
    <name>A0A1J1GS28_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00007300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528118.1">
        <property type="nucleotide sequence ID" value="XM_028671469.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728595"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00007300"/>
    <dbReference type="OrthoDB" id="439792at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13402:SF29">
        <property type="entry name" value="ANCESTRAL COATOMER ELEMENT 1 SEC16_SEC31 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13402">
        <property type="entry name" value="RGPR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="535"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="644"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1746"/>
            <end position="2031"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3029"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3070"/>
            <end position="3091"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="768"/>
            <end position="829"/>
        </location>
    </feature>
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        <location>
            <begin position="1243"/>
            <end position="1313"/>
        </location>
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        <location>
            <begin position="2584"/>
            <end position="2618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="541"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="644"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="654"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="676"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
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        </location>
    </feature>
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        <location>
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            <end position="1844"/>
        </location>
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        <location>
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        </location>
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        </location>
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        <location>
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        </location>
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        <location>
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            <end position="1980"/>
        </location>
    </feature>
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        <location>
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        </location>
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        <location>
            <begin position="1991"/>
            <end position="2010"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2011"/>
            <end position="2030"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3825" mass="461654" checksum="3534867488DCA378" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS81</accession>
    <name>A0A1J1GS81_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527977.1">
        <property type="nucleotide sequence ID" value="XM_028671313.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS81"/>
    <dbReference type="GeneID" id="39731097"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00256900"/>
    <dbReference type="OMA" id="WRWCDKR"/>
    <dbReference type="OrthoDB" id="370373at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="871" mass="104298" checksum="524B8AD18D854933" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSB6</accession>
    <name>A0A1J1GSB6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00260100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_028671348.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSB6"/>
    <dbReference type="GeneID" id="39731130"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00260100"/>
    <dbReference type="OMA" id="FIYVHKR"/>
    <dbReference type="OrthoDB" id="510307at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004452">
        <property type="term" value="F:isopentenyl-diphosphate delta-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009240">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
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    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10885">
        <property type="entry name" value="ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10885:SF0">
        <property type="entry name" value="ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="40"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="191" mass="22729" checksum="C7C10681E3B81C8D" modified="2017-02-15" version="1">MKDYINYNFEDNKSELVIIVNDKNEFQELQTRKVMRKNNLWHRSTSILVLSKNEQNILIYIHKRSKIKDYCPSYYSIGFGGVLSENENFLQNAVKELYEESGIVKKPEQLFDLGLIKCETEYIKAYITFIHPDFQTTPQLNEVEFISKISLNDLDDFVKKEEVTQISKNVYHYFKDQIKKINLDEIYNMTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSP8</accession>
    <name>A0A1J1GSP8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00267200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000036">
        <property type="protein sequence ID" value="CRG95469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528279.1">
        <property type="nucleotide sequence ID" value="XM_028671648.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSP8"/>
    <dbReference type="GeneID" id="39731201"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00267200"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="295" mass="35609" checksum="A21B6DE9BF3E6307" modified="2017-02-15" version="1">MKTLILFLKITTFLLLIWMYQFFYNCDSYKTLIDKYILQTKNELKYERILAEGNTEGKEQTKAEECLEKFPLDNKENKCEDPVQYENPYDYWHNVINPQLWEEFNQETSGMDPKVKEKKWNVKWKKISDKKANELSSIFHRSDISEEEKGKLIDSVKKELHIEFVKFLCECKNEMRRKKRESESRKEMKDNKIVSESTKEMKDNKTVSESTKEMRDNKIESEYNKELRDNKTESESNKEMTDNKTESESMKEITENEAESKSKKEQRKNKINIKNFDFMKHLIFHKINKIYDNKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSR2</accession>
    <name>A0A1J1GSR2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-f protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00273100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000043">
        <property type="protein sequence ID" value="CRG95531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528340.1">
        <property type="nucleotide sequence ID" value="XM_028671715.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSR2"/>
    <dbReference type="GeneID" id="39731263"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00273100"/>
    <dbReference type="OMA" id="HELLCRK"/>
    <dbReference type="OrthoDB" id="384111at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="587" mass="69932" checksum="2A10482114762207" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSX1</accession>
    <name>A0A1J1GSX1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Secretory complex protein 61 gamma subunit, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00015100</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SecE/SEC61-gamma family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528193.1">
        <property type="nucleotide sequence ID" value="XM_028671552.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSX1"/>
    <dbReference type="GeneID" id="39728673"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00015100"/>
    <dbReference type="OMA" id="KPDQKEY"/>
    <dbReference type="OrthoDB" id="2401875at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.820">
        <property type="entry name" value="Preprotein translocase SecE subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00422">
        <property type="entry name" value="SecE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023391">
        <property type="entry name" value="Prot_translocase_SecE_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008158">
        <property type="entry name" value="Translocase_Sec61-g"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001901">
        <property type="entry name" value="Translocase_SecE/Sec61-g"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00327">
        <property type="entry name" value="secE_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12309">
        <property type="entry name" value="SEC61 GAMMA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00584">
        <property type="entry name" value="SecE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103456">
        <property type="entry name" value="Preprotein translocase SecE subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="49"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG95382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="82" mass="9343" checksum="AA644BAADC754BA4" modified="2017-02-15" version="1">MVKVKIPEFITDESHPIGYCVKGIESFVSDSIRLIRKCTKPNKKEYTNIVYACSFGFLIMGFIGYMIKLVFIPINNILVGSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT89</accession>
    <name>A0A1J1GT89_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Endonuclease/exonuclease/phosphatase family protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00397100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527088.1">
        <property type="nucleotide sequence ID" value="XM_028670325.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT89"/>
    <dbReference type="GeneID" id="39732501"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00397100"/>
    <dbReference type="OMA" id="YTNWNNN"/>
    <dbReference type="OrthoDB" id="412787at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000288">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050410">
        <property type="entry name" value="CCR4/nocturin_mRNA_transcr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121:SF37">
        <property type="entry name" value="2',5'-PHOSPHODIESTERASE 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121">
        <property type="entry name" value="CARBON CATABOLITE REPRESSOR PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012498285" evidence="2">
        <location>
            <begin position="23"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="3">
        <location>
            <begin position="530"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="839" mass="99838" checksum="C27720967A9C3656" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTB6</accession>
    <name>A0A1J1GTB6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">40S ribosomal protein S15A, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00399500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527112.1">
        <property type="nucleotide sequence ID" value="XM_028670351.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTB6"/>
    <dbReference type="GeneID" id="39732525"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00399500"/>
    <dbReference type="OMA" id="LPAKNFG"/>
    <dbReference type="OrthoDB" id="10250260at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.30:FF:000001">
        <property type="entry name" value="40S ribosomal protein S15a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S15a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000630">
        <property type="entry name" value="Ribosomal_uS8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047863">
        <property type="entry name" value="Ribosomal_uS8_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035987">
        <property type="entry name" value="Ribosomal_uS8_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003115">
        <property type="entry name" value="PRK04034.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11758">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S15A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00410">
        <property type="entry name" value="Ribosomal_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56047">
        <property type="entry name" value="Ribosomal protein S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00053">
        <property type="entry name" value="RIBOSOMAL_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="130" mass="14971" checksum="4F1954A20373003F" modified="2017-02-15" version="1">MVRMSVLADCLKTINNAEKRGRRQVLIRPSSKVVIRFLRYMQKKGYIGNFEIVDDHRSGKIVVNLLGRINKCAVISPRYDVKLEEIEKIITSILPSRLFGHLILTTPYGIMDHEEARRKHTGGKVLGFFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTQ1</accession>
    <name>A0A1J1GTQ1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ER membrane protein complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">EMC2</name>
        <name evidence="5" type="ORF">PGAL8A_00281600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the ER membrane protein complex (EMC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the EMC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528427.1">
        <property type="nucleotide sequence ID" value="XM_028671812.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTQ1"/>
    <dbReference type="GeneID" id="39731349"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00281600"/>
    <dbReference type="OMA" id="MSDQEGW"/>
    <dbReference type="OrthoDB" id="124397at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072546">
        <property type="term" value="C:EMC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039856">
        <property type="entry name" value="EMC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055217">
        <property type="entry name" value="TPR_EMC2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12760">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22890">
        <property type="entry name" value="TPR_EMC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="EMC2 TPR-like" evidence="4">
        <location>
            <begin position="93"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU367091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="293" mass="34969" checksum="03C586942F28D763" modified="2017-02-15" version="1">MVENKVVYNKENNLNSLEKCYQNSLEKNISELVIIYGTKLIKRNIKKDSFYKWNIYENILRASIELNLDEYIDIYFNKLNEKFGNLNGKKIDILKGMIYESKNKNTEALNIYKKCLCKYPCDPLVRTKIINLKKILENDINKVVQLLNNHLKEFPLDLESWHELAEIYLKDCLYSYSLYCFEEILLHLPTNLYYILTCAELYYTLNQYELSSKYFCLSIKIQNNNLRGLWGIILLNITRYSNKKTKLLNDNVDIILTLKCINRLFDLYSKLNINLLYKNSILDYLNQLRDNFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTR9</accession>
    <name>A0A1J1GTR9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Fam-b protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00305900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528655.1">
        <property type="nucleotide sequence ID" value="XM_028672064.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTR9"/>
    <dbReference type="GeneID" id="39731592"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00305900"/>
    <dbReference type="OMA" id="YKRYHCI"/>
    <dbReference type="OrthoDB" id="392883at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009618942" description="Fam-b protein" evidence="3">
        <location>
            <begin position="22"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="261"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="280" mass="32882" checksum="ECE819C9ACAF3E40" modified="2017-02-15" version="1">MKIYLIILNFIIFDFLNCVESTKISHNEVEEIGVSEQALKKLQELKKLELDLLIDIVKKDIYNKDTYTKYHCISSDYALFNKKDEISNYNKHENNNTEQNKEDSESIHNGQNKKSTSFINKITSFLGIFHYSNKNKISPKINIQEYNIKNEENDDKYSAETSALIHEQKPNSYMQLKGFSLIKKNNLFGSKESSNENAEIGNYGSFFFIFGTSNTDYPWACVCDPHQLIEYKKKKRTYVLCHNQIDMSIQNSDLICNYENFSYNIHLCYIFIFLIILIYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTZ3</accession>
    <name>A0A1J1GTZ3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="1">PPIase</shortName>
            <ecNumber evidence="1">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00319300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6 7">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528788.1">
        <property type="nucleotide sequence ID" value="XM_028672214.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTZ3"/>
    <dbReference type="GeneID" id="39731726"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00319300"/>
    <dbReference type="OMA" id="IPNPRVY"/>
    <dbReference type="OrthoDB" id="193499at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000031">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="2">
        <location>
            <begin position="9"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="226" mass="26621" checksum="D35B2866FEA6CE8A" modified="2017-02-15" version="1">MKIPNPRVYLDVAIGGRNAGRMIFELFMDKLPITCENFRCLCTGETGLGYYLKPRWYKNTPIHRIVTDFMFQGGDFNFGNGFGGESIYGQYFRNEKFIYKHSKRGVLSMCQTRIKHTNNSQFFVTFKSCPWLDKKHVVFGHLEYGFETLSFIEEQSTLIGKPKKQVYIYNCGEIPLDKIKYKSYRNSSDDYIIPDIEMPLLEKDIDFNENTDFNELKKIYKNSKRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUG8</accession>
    <name>A0A1J1GUG8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit C</fullName>
            <shortName evidence="4">eIF3c</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit 8</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00315800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eIF-3 subunit C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528753.1">
        <property type="nucleotide sequence ID" value="XM_028672173.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUG8"/>
    <dbReference type="GeneID" id="39731691"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00315800"/>
    <dbReference type="OMA" id="FRCGLIK"/>
    <dbReference type="OrthoDB" id="29647at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03002">
        <property type="entry name" value="eIF3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027516">
        <property type="entry name" value="EIF3C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008905">
        <property type="entry name" value="EIF3C_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13937">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITATION FACTOR 3, SUBUNIT 8 EIF3S8 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13937:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05470">
        <property type="entry name" value="eIF-3c_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="6">
        <location>
            <begin position="678"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="159"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="513"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="893"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="164"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="197"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="214"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="513"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="527"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="893"/>
            <end position="908"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="936" mass="110626" checksum="E8027A2427CD35DB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUK5</accession>
    <name>A0A1J1GUK5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00319800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528793.1">
        <property type="nucleotide sequence ID" value="XM_028672219.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUK5"/>
    <dbReference type="GeneID" id="39731731"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00319800"/>
    <dbReference type="OMA" id="IKFCVEY"/>
    <dbReference type="OrthoDB" id="361835at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33828:SF2">
        <property type="entry name" value="NUCLEOLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33828">
        <property type="entry name" value="OS05G0596200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="198" mass="22659" checksum="0D303B833B796611" modified="2017-02-15" version="1">MLSSSDLSSTKKDEYLKNSNKKIENSNSTKHVKKNCNNISKVNKGLNQNNKVKNEKNNKKKKIKKGNSSSKTTVKEMIDEDEEEEDKDNICADARKYFKEGQKIITPPNGDGTRAFYESLFEENPNSVIAIKYCIEHGVLSGTKHHEALYKYFILKKNNAFKSNFGGIKSEFLKLLEDSCKNEKCSYEELIKKEILSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUL9</accession>
    <name>A0A1J1GUL9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Palmitoyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">DHHC9</name>
        <name evidence="9" type="ORF">PGAL8A_00342500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529012.1">
        <property type="nucleotide sequence ID" value="XM_028672462.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUL9"/>
    <dbReference type="GeneID" id="39731955"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00342500"/>
    <dbReference type="OMA" id="FQTEHEY"/>
    <dbReference type="OrthoDB" id="9909019at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12246">
        <property type="entry name" value="PALMITOYLTRANSFERASE ZDHHC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="8">
        <location>
            <begin position="94"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG96207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="292" mass="34846" checksum="53F31579D61EC283" modified="2017-02-15" version="1">MNNYLSFILVTILSIFIYVCYIYSLQNEYLNNYSKITRILLAVFSIPFFICYYWSFVKCSLSGPGYVDDSWELNAEENNIQIEKKKIRNYTPNKYTVCDKCNYLVRPERAHHCRSCKKCVLKMDHHCPWIGTCVGEKNLKFFFLFLLYGFFITFYIIATIMPKFIRSLYSRETMVLVNVNHATLLITICAALTLFLALLFMNCQYIYFISRNVTVIESSYNDINPYDLGIYNNWKMVFGEFKWKWFFPFNPENLYQTNSLYPLNDRYMNINNIDLEDSFLTSHNFISKEENH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUP0</accession>
    <name>A0A1J1GUP0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="2">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00338800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528975.1">
        <property type="nucleotide sequence ID" value="XM_028672420.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUP0"/>
    <dbReference type="GeneID" id="39731918"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00338800"/>
    <dbReference type="OMA" id="KISGMWF"/>
    <dbReference type="OrthoDB" id="422700at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040053">
        <property type="entry name" value="JOSD1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006155">
        <property type="entry name" value="Josephin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13291">
        <property type="entry name" value="JOSEPHIN 1, 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13291:SF0">
        <property type="entry name" value="JOSEPHIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02099">
        <property type="entry name" value="Josephin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01246">
        <property type="entry name" value="Josephin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50957">
        <property type="entry name" value="JOSEPHIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Josephin" evidence="7">
        <location>
            <begin position="15"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="28"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="234" mass="28174" checksum="0434E5380D193FE0" modified="2017-02-15" version="1">MCHYDTIIIETEKGSVNVYFEKQSRLFCLVHTTNNILQAHVYSPDDFKNIESKLNYSDLETNELKNNNDKNLEEKYSFDIKRENEINYKNIFSYFKRGTFFFGNFNINILYFLMNKHNIELCWVDNKEIFEKINNNNCSTIFDDKHLNNKNLIAFIINVVKIKFFDLYYHRHFYTIRKISGLWFHLDSSLHKPIMLPSNKDVNDHLISILKDNKFHKSDNYIIQVFKKEKHNSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUV3</accession>
    <name>A0A1J1GUV3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tyrosine kinase-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">TKL2</name>
        <name evidence="5" type="ORF">PGAL8A_00347900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529066.1">
        <property type="nucleotide sequence ID" value="XM_028672522.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732009"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00347900"/>
    <dbReference type="OMA" id="MNCYFLK"/>
    <dbReference type="OrthoDB" id="1714095at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR27001">
        <property type="entry name" value="OS01G0253100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR27001:SF931">
        <property type="entry name" value="OS11G0664100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="137"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="900"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="901"/>
            <end position="922"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1350" mass="161327" checksum="745ABAB7276D6156" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUZ5</accession>
    <name>A0A1J1GUZ5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00226200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527680.1">
        <property type="nucleotide sequence ID" value="XM_028670982.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUZ5"/>
    <dbReference type="GeneID" id="39730789"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00226200"/>
    <dbReference type="OrthoDB" id="372073at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016903">
        <property type="entry name" value="Nucleolar_cplx-assoc_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14428">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14428:SF5">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="817"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="55"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="817"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="852"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="852" mass="101522" checksum="C0A21BF420FC60ED" modified="2017-02-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV94</accession>
    <name>A0A1J1GV94_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Adrenodoxin reductase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00367200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529252.1">
        <property type="nucleotide sequence ID" value="XM_028672728.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV94"/>
    <dbReference type="GeneID" id="39732202"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00367200"/>
    <dbReference type="OMA" id="AYVITQA"/>
    <dbReference type="OrthoDB" id="333024at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055275">
        <property type="entry name" value="Ferredox_Rdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48467">
        <property type="entry name" value="GLUTAMATE SYNTHASE 1 [NADH], CHLOROPLASTIC-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48467:SF1">
        <property type="entry name" value="GLUTAMATE SYNTHASE 1 [NADH], CHLOROPLASTIC-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00419">
        <property type="entry name" value="ADXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51971">
        <property type="entry name" value="Nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="487" mass="57599" checksum="56A88DEEE336A449" modified="2017-02-15" version="1">MILYEILFNTRIKSIKFKSKEKNLFYFKKNFFSNEKKYFKIGIVGAGPSALYCCKYFLKNDNIKVDIFDKLPNPYGLIRYGVAPDHVQVKNTYKTFDTVFLNKNYRFFGNVNIGVDLKIEDLRNYYNVCIFCCGASDISLPNLENEENNGIFHAKDLIYYYNNYYEELRCKNVDNYLNSFDNFTNSVIIGNGNVSLDIARILTKSDDDLKKTDININFLNSKKKHHFKHIYIIGRRGFWQSSFTNGELRELLTLNNTKVILNKDNYDLCFHLKNYDENSSIKQRQNKLFLNMVKNYEDLEKNKNLYENHKIIEFIFYYEIKKVNYINNYMKNIEFEINKNLQISNPSIQKKYLTTPLLIFATGFKKNAFNENLYNKSIEKFKEDILSNKFGIFKAGWFDGGAKGNIASQIVNSKNRISLILNFLQNTTTFFDNDICTLLNKKKIHFVNFNDWIYIKNYEEQNGIQKGKITEKFNTVKQILQILDERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVE6</accession>
    <name>A0A1J1GVE6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00368600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529266.1">
        <property type="nucleotide sequence ID" value="XM_028672744.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732216"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00368600"/>
    <dbReference type="OMA" id="GGNIIKY"/>
    <dbReference type="OrthoDB" id="381824at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="804"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1154"/>
            <end position="1191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1356"/>
            <end position="1393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1559"/>
            <end position="1588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1617"/>
            <end position="1639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2187"/>
            <end position="2210"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="934"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1158"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1174"/>
            <end position="1188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1374"/>
            <end position="1385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1560"/>
            <end position="1575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1576"/>
            <end position="1588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1617"/>
            <end position="1626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3189" mass="370699" checksum="111764FDC5D326EC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVL9</accession>
    <name>A0A1J1GVL9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00358800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529169.1">
        <property type="nucleotide sequence ID" value="XM_028672636.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732118"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00358800"/>
    <dbReference type="OMA" id="WIYRYIN"/>
    <dbReference type="OrthoDB" id="377924at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1201"/>
            <end position="1221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1241"/>
            <end position="1259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1280"/>
            <end position="1300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1320"/>
            <end position="1338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1501"/>
            <end position="1518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1522" mass="185208" checksum="0C7A37D4BDF3BE7C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVP4</accession>
    <name>A0A1J1GVP4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Peptide deformylase</fullName>
            <ecNumber evidence="2 7">3.5.1.88</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PDF</name>
        <name evidence="10" type="ORF">PGAL8A_00420600</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Removes the formyl group from the N-terminal Met of newly synthesized proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>N-terminal N-formyl-L-methionyl-[peptide] + H2O = N-terminal L-methionyl-[peptide] + formate</text>
            <dbReference type="Rhea" id="RHEA:24420"/>
            <dbReference type="Rhea" id="RHEA-COMP:10639"/>
            <dbReference type="Rhea" id="RHEA-COMP:10640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:49298"/>
            <dbReference type="ChEBI" id="CHEBI:64731"/>
            <dbReference type="EC" id="3.5.1.88"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the polypeptide deformylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.88" evidence="2 7"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529430.1">
        <property type="nucleotide sequence ID" value="XM_028672926.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVP4"/>
    <dbReference type="GeneID" id="39732738"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00420600"/>
    <dbReference type="OMA" id="VCIQHEI"/>
    <dbReference type="OrthoDB" id="276063at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042586">
        <property type="term" value="F:peptide deformylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00487">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.45.10:FF:000005">
        <property type="entry name" value="Peptide deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.45.10">
        <property type="entry name" value="Peptide deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00163">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023635">
        <property type="entry name" value="Peptide_deformylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036821">
        <property type="entry name" value="Peptide_deformylase_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00079">
        <property type="entry name" value="pept_deformyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001159">
        <property type="entry name" value="PRK00150.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10458">
        <property type="entry name" value="PEPTIDE DEFORMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10458:SF22">
        <property type="entry name" value="PEPTIDE DEFORMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01327">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004749">
        <property type="entry name" value="Pep_def"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01576">
        <property type="entry name" value="PDEFORMYLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56420">
        <property type="entry name" value="Peptide deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012249870" description="Peptide deformylase" evidence="9">
        <location>
            <begin position="23"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="204"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG96626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="235" mass="27722" checksum="B95DAB73A5870738" modified="2017-02-15" version="1">MDVLKYCLVLLLLEHYFKTSLGHIISKKLKFYIKNYKSNNIRKNRNVIIHLTRESNKEIKIVKYPNPVLRKKCEDVINFDDNLKNLIRIMFNIMYENKGIGLSAPQVNISKKIIVWNALYEKRKSENERVFINPSIVEQSLIKTKLVEGCLSFPNVEGKIERPNIVSVSYFDLEGNKHLKILKGIHSRIFQHEYDHLNGILFIDRMTQNEKKKIKAKLNQLTQEYKKNYSEEPAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVQ3</accession>
    <name>A0A1J1GVQ3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">6-phosphofructokinase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00355200</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529139.1">
        <property type="nucleotide sequence ID" value="XM_028672603.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732082"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00355200"/>
    <dbReference type="OMA" id="TWAYNDC"/>
    <dbReference type="OrthoDB" id="370357at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00182"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003872">
        <property type="term" value="F:6-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009749">
        <property type="term" value="P:response to glucose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.450">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.460">
        <property type="entry name" value="Phosphofructokinase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000023">
        <property type="entry name" value="Phosphofructokinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035966">
        <property type="entry name" value="PKF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43650">
        <property type="entry name" value="PYROPHOSPHATE--FRUCTOSE 6-PHOSPHATE 1-PHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43650:SF1">
        <property type="entry name" value="PYROPHOSPHATE--FRUCTOSE 6-PHOSPHATE 1-PHOSPHOTRANSFERASE SUBUNIT BETA 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00365">
        <property type="entry name" value="PFK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53784">
        <property type="entry name" value="Phosphofructokinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphofructokinase" evidence="8">
        <location>
            <begin position="117"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphofructokinase" evidence="8">
        <location>
            <begin position="796"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="3"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG96334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1308" mass="152540" checksum="D8625CC51DF1F5F2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVT7</accession>
    <name>A0A1J1GVT7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CST complex subunit STN1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Suppressor of cdc thirteen homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00359800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Telomere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529179.1">
        <property type="nucleotide sequence ID" value="XM_028672648.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVT7"/>
    <dbReference type="GeneID" id="39732128"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00359800"/>
    <dbReference type="OMA" id="EFKIHDF"/>
    <dbReference type="OrthoDB" id="369318at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040260">
        <property type="entry name" value="RFA2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13989:SF33">
        <property type="entry name" value="CST COMPLEX SUBUNIT STN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13989">
        <property type="entry name" value="REPLICATION PROTEIN A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0779">Telomere</keyword>
    <feature type="domain" description="OB" evidence="9">
        <location>
            <begin position="83"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG96374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="273" mass="31956" checksum="450E9554A9FBE0AC" modified="2017-02-15" version="1">MDMNFGFCDDTFFEQGNKSTDKEEIEEIKKNESFEAITKNKETEEEKVLPKELCVPVTIKLLLNKMKNSEEFKIHDFQISGIIVFGKVCKVKELASAIIFEICDYTGNIEAKYNKDAKNEKVQNHIENIKVNDHIKVVGVVYSPETKSEFVQISISYVNKVDDWLSYFSYFTSDVIYCYLKLLKLKNIYAPNGINNEEKPWSHITLDSYYNHLDDTDTDIIKYLHTKDEKYANQQDIFNNLQKYHSEINIKKSLTKLIEQYDLAQYEDIISIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVU8</accession>
    <name>A0A1J1GVU8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Phosphoenolpyruvate/phosphate translocator, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PPT</name>
        <name evidence="7" type="ORF">PGAL8A_00414300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529367.1">
        <property type="nucleotide sequence ID" value="XM_028672856.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVU8"/>
    <dbReference type="GeneID" id="39732673"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00414300"/>
    <dbReference type="OMA" id="LWYVCNI"/>
    <dbReference type="OrthoDB" id="6418713at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="283"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="327"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="394"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="431"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="6">
        <location>
            <begin position="188"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="513" mass="58469" checksum="249A7DA6F1DF945D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWC2</accession>
    <name>A0A1J1GWC2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">High molecular weight rhoptry protein 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">RhopH2</name>
        <name evidence="2" type="ORF">PGAL8A_00442200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529644.1">
        <property type="nucleotide sequence ID" value="XM_028673163.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732955"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00442200"/>
    <dbReference type="OrthoDB" id="391866at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012204616" evidence="1">
        <location>
            <begin position="24"/>
            <end position="1348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1348" mass="160478" checksum="8B5FEB3AF8B9E1B2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWI1</accession>
    <name>A0A1J1GWI1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00013400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528176.1">
        <property type="nucleotide sequence ID" value="XM_028671534.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWI1"/>
    <dbReference type="GeneID" id="39728656"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00013400"/>
    <dbReference type="OMA" id="KDEYYTH"/>
    <dbReference type="OrthoDB" id="372430at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="336"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="364" mass="44688" checksum="102F42156578CD9E" modified="2017-02-15" version="1">MLENLCINLINELFLAKHNFLIFIILSDLHKNGKSSKKAKKKKITTNIEKKNELAYFNIFKKNCYLKFCSIKKKQIKRRRIIRIKFKKLRKTIKEMDENYNRYKYKTNDFNLEHKHNYYKFIKNITLFLHSFEKDLIFKKISYKIMKKIYYKKNKNVKCFKKKILPYKLKKKSNFIHIRNKKKYVDFLNSNLYDYVYKDIYNFLPNYNFEKDLNLNKKNLNCVFNKEKVDQILKKKKEIVRKIYIKNKTYTLSSKKLKKRYNEFYEKFCSFLIKLKVDKKDETKQLVSDYKVLKTLLYLKNSNISKNLDNNSLIKSKNYKIHEVISMINYLKKGLYIIKMDIIYIYIFFCSYINNIFSKLKSFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWX4</accession>
    <name>A0A1J1GWX4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00271900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000041">
        <property type="protein sequence ID" value="CRG95519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528328.1">
        <property type="nucleotide sequence ID" value="XM_028671702.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWX4"/>
    <dbReference type="GeneID" id="39731251"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00271900"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="304" mass="36527" checksum="E28B6FC5895EB632" modified="2017-02-15" version="1">MKTLTLYLKISTFLLFIWIYQCFYNCDSYKTLVDKNILQTKNELKYERVLTEGDIAEKKKTNTEGCLQECPLDNKKNKCKEPDLYNDPCNYLCEVIVPQFLERFNNEISEKDPKSKSLKWNDYWNKILTTKVKELFSIYHRRNIPDEEINKKIDSIMREVNSEFEKFLCECKNQMTDNKTESEYKKEMRKNKTESESKRKMIDHKAESESKKELIDDKTESQNMKELIENKTEFECRNKMIENKTEFECRNEMIDNKTESESMKEMIDNKAESESWKEQESNEINNCKLKIFKLHIVLIILSRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWZ6</accession>
    <name>A0A1J1GWZ6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00436600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CFAP298 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529587.1">
        <property type="nucleotide sequence ID" value="XM_028673101.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWZ6"/>
    <dbReference type="GeneID" id="39732898"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00436600"/>
    <dbReference type="OMA" id="YRKQEEW"/>
    <dbReference type="OrthoDB" id="276065at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003352">
        <property type="term" value="P:regulation of cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021298">
        <property type="entry name" value="CFAP298"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13238:SF0">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13238">
        <property type="entry name" value="PROTEIN C21ORF59"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11069">
        <property type="entry name" value="CFAP298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="280" mass="32772" checksum="56B3C19210C89578" modified="2017-02-15" version="1">MVLIHVKSVEDSHQFLYETNVNVLIKNLKEDLVNIHNLRCKILKLLEASLDLANHGPMRPEELRGLSEDELKISKLNIYEWKEATNPDKYNFRTGIPPPSDGAIKLKNIVDKVKKELSIEKIEQNKPINTNNLYEHLNMITEALNICYPSMEKLPPYDPTRILIEKDNFFNDEFISNETSLWWAGKELSEELYLKNIIGKNEKTKIIVRVQPKKLGPPIREARIDSETYKAMLAYYHKKQKEEKEFEEDDDDSYLNSEWANPLSLQKQLHGNLNNIKWKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX70</accession>
    <name>A0A1J1GX70_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Plasmodium RESA N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00474200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000088">
        <property type="protein sequence ID" value="CRG97163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529966.1">
        <property type="nucleotide sequence ID" value="XM_028673522.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX70"/>
    <dbReference type="GeneID" id="39733275"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00474200"/>
    <dbReference type="OMA" id="ESNCANP"/>
    <dbReference type="OrthoDB" id="384212at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.180">
        <property type="entry name" value="Plasmodium RESA, N-terminal helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006526">
        <property type="entry name" value="Export_prot_PHISTa/b/c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019111">
        <property type="entry name" value="PRESA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044885">
        <property type="entry name" value="PRESA_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01639">
        <property type="entry name" value="P_fal_TIGR01639"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36193">
        <property type="entry name" value="PHISTB DOMAIN-CONTAINING RESA-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36193:SF23">
        <property type="entry name" value="PHISTB DOMAIN-CONTAINING RESA-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09687">
        <property type="entry name" value="PRESAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="Plasmodium RESA N-terminal" evidence="2">
        <location>
            <begin position="198"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="342" mass="41182" checksum="5A013082ED97725F" modified="2017-02-15" version="1">MRHSNTINFILQRRFLVSSNASISNLDVSSFNRGKKNFQKRIFSNFLFSKLFILYFFSVLYLFSLHICVSKDNAFSELQLNKVYNRKLAEHIPEKGEDSKQKKTNFDINEDEKLQSNYRSSIKSELNQSDKHNHEVMSESKKKQILEESDRIEKKNDNVHAKMDKREMNDEMGKQKIQNEGCAISLGKRSSELNYQMCEDEIIERIQNLDNNPSIEDIYILWWQVRGDQRNNFLEIIEYLKYIFYSLTNKYNFEECFIKKEWNKWYHGVLSDLINMETIDNKNFYSIYKKETWTREKFKDFIDKNILVWKNHKMSTKKKWENILTDDFINEEKKRADNSQQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXH3</accession>
    <name>A0A1J1GXH3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00484700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530070.1">
        <property type="nucleotide sequence ID" value="XM_028673637.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733380"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00484700"/>
    <dbReference type="OMA" id="FVHEIYE"/>
    <dbReference type="OrthoDB" id="372561at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141571">
        <property type="entry name" value="Pentapeptide repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="28"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="253"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="299"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="389"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="598"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="627"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="698"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="730"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="784"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1341"/>
            <end position="1377"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1261"/>
            <end position="1323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1377" mass="167654" checksum="E4A2DFC1658B2DF2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXJ0</accession>
    <name>A0A1J1GXJ0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Biotin--acetyl-CoA-carboxylase, putative</fullName>
            <ecNumber evidence="4">6.4.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00486100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the biotin--protein ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.4.1.2" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530084.1">
        <property type="nucleotide sequence ID" value="XM_028673653.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXJ0"/>
    <dbReference type="GeneID" id="39733394"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00486100"/>
    <dbReference type="OMA" id="MLIIREA"/>
    <dbReference type="OrthoDB" id="10250105at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004077">
        <property type="term" value="F:biotin--[biotin carboxyl-carrier protein] ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004408">
        <property type="entry name" value="Biotin_CoA_COase_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00121">
        <property type="entry name" value="birA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12835">
        <property type="entry name" value="BIOTIN PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12835:SF5">
        <property type="entry name" value="BIOTIN--PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03099">
        <property type="entry name" value="BPL_LplA_LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="3">
        <location>
            <begin position="22"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="283" mass="32918" checksum="8050CF26D1CF0366" modified="2017-02-15" version="1">MQEKILFEKFYSEINALRFHFDVLDSTQLYCKRNMQLFIETGKLKDDNMIIVSCNSQTNGIGTRDTKKNINRFWLSKEGNIFATFVFLWDKRDINKVSCLAQTSTVAISKTLEYFHLITQIKWINDVLINNKKISGCLVNLYHFDDDILSKNYVCIMVGIGINVDLRDDKNLLSNNYTSIKKELEQDFDVPSLIPSVEDVMQKLIENFHASIKKLRNEGFSAFLDYIKIRLLYYEKKILIDQDNRQITGYLKGLLDDGSILLLNENNQIININNGHLYLNEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXR3</accession>
    <name>A0A1J1GXR3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Delta-aminolevulinic acid synthetase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00466700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529889.1">
        <property type="nucleotide sequence ID" value="XM_028673437.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXR3"/>
    <dbReference type="GeneID" id="39733200"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00466700"/>
    <dbReference type="OMA" id="WFNKESA"/>
    <dbReference type="OrthoDB" id="10263824at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003870">
        <property type="term" value="F:5-aminolevulinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006783">
        <property type="term" value="P:heme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06454">
        <property type="entry name" value="KBL_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000006">
        <property type="entry name" value="5-aminolevulinate synthase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010961">
        <property type="entry name" value="4pyrrol_synth_NH2levulA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050087">
        <property type="entry name" value="AON_synthase_class-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01821">
        <property type="entry name" value="5aminolev_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693:SF102">
        <property type="entry name" value="2-AMINO-3-KETOBUTYRATE COENZYME A LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13693">
        <property type="entry name" value="CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="6">
        <location>
            <begin position="247"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="619" mass="71538" checksum="0C0AFE226EA9DF9A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY12</accession>
    <name>A0A1J1GY12_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00476900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529993.1">
        <property type="nucleotide sequence ID" value="XM_028673552.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY12"/>
    <dbReference type="GeneID" id="39733302"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00476900"/>
    <dbReference type="OMA" id="YMLHRIN"/>
    <dbReference type="OrthoDB" id="376859at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="135"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="918" mass="109654" checksum="36064F43C06A10A8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYC5</accession>
    <name>A0A1J1GYC5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mitochondrial ATP synthase delta subunit, putative</fullName>
            <ecNumber evidence="9">3.6.3.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">OSCP</name>
        <name evidence="9" type="ORF">PGAL8A_00506100</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase delta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.14" evidence="9"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530289.1">
        <property type="nucleotide sequence ID" value="XM_028673881.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYC5"/>
    <dbReference type="GeneID" id="39733594"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00506100"/>
    <dbReference type="OMA" id="YSIEGLY"/>
    <dbReference type="OrthoDB" id="1262810at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.20">
        <property type="entry name" value="N-terminal domain of the delta subunit of the F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01416">
        <property type="entry name" value="ATP_synth_delta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026015">
        <property type="entry name" value="ATP_synth_OSCP/delta_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000711">
        <property type="entry name" value="ATPase_OSCP/dsu"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01145">
        <property type="entry name" value="ATP_synt_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11910">
        <property type="entry name" value="ATP SYNTHASE DELTA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00213">
        <property type="entry name" value="OSCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00125">
        <property type="entry name" value="ATPASEDELTA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47928">
        <property type="entry name" value="N-terminal domain of the delta subunit of the F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="4" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG97488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="246" mass="29622" checksum="085227ED47AE9C6B" modified="2017-02-15" version="1">MKTFNYCNYRYLSNLVNKNRWYYILKNNYSFYNLGKNYINDSKKTINYYRNFSTQEEKNNDDYFSSMGDNIEKRYSLALYNVGKKNNKINEITNDLLFIKNGLLKDKTFLNFLHTPNIERKEKLDFLKNECKKFNKFNSITLNFLESLFDSKRMNFLQKIIEEFELLLMREKKEIKCIVYTAREIDNNYKKKIHDSIVFKLKNELKPLIEFKTDKFILGGLILQIGTQVFDFSAKSKIERIRNSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYL5</accession>
    <name>A0A1J1GYL5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00498200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000105">
        <property type="protein sequence ID" value="CRG97407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530209.1">
        <property type="nucleotide sequence ID" value="XM_028673792.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733515"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00498200"/>
    <dbReference type="OMA" id="CICDEML"/>
    <dbReference type="OrthoDB" id="377116at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="844"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="645"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="850"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="892" mass="109967" checksum="8F23AAAF9DAD71D9" modified="2017-02-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYT5</accession>
    <name>A0A1J1GYT5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphatidylinositol N-acetylglucosaminyltransferase subunit H, putative</fullName>
            <ecNumber evidence="5">2.4.1.198</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">PIGH</name>
        <name evidence="5" type="ORF">PGAL8A_00368900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PIGH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.198" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529269.1">
        <property type="nucleotide sequence ID" value="XM_028672747.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYT5"/>
    <dbReference type="GeneID" id="39732219"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00368900"/>
    <dbReference type="OMA" id="YIFEICP"/>
    <dbReference type="OrthoDB" id="6256716at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000506">
        <property type="term" value="C:glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017176">
        <property type="term" value="F:phosphatidylinositol N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044215">
        <property type="entry name" value="PIG-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019328">
        <property type="entry name" value="PIGH-H_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15231">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15231:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10181">
        <property type="entry name" value="PIG-H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidylinositol N-acetylglucosaminyltransferase subunit H conserved" evidence="4">
        <location>
            <begin position="80"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="243" mass="29291" checksum="DD44F51A9AB129D9" modified="2017-02-15" version="1">MKNKIRRIEHLCGIEYISEKKEKRKFVFFVLFIFSLYYMYYIYTAHKQGYLTIDEFQILLFFLYILLIITYLNNYSIEKLLLINNIGIQIEKENLFKHHLKFICANDIKSVFINEVIYIFEISPYLCLTLKNNNLIVVFEDFNLEMKNLVNIYRDIKKTFFFDDYKKLTNVKAEFIKNEEESITHNDTYSAKNNSSSEENIFKMLNITSCENFKINNQINFSPKKKTFDIYINKKLALEIMNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ12</accession>
    <name>A0A1J1GZ12_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00412600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000063">
        <property type="protein sequence ID" value="CRG96544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529349.1">
        <property type="nucleotide sequence ID" value="XM_028672836.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ12"/>
    <dbReference type="GeneID" id="39732656"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00412600"/>
    <dbReference type="OMA" id="HSEDEWI"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="570" mass="70958" checksum="17A43494569494B5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ23</accession>
    <name>A0A1J1GZ23_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00348500</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529072.1">
        <property type="nucleotide sequence ID" value="XM_028672528.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ23"/>
    <dbReference type="GeneID" id="39732015"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00348500"/>
    <dbReference type="OMA" id="QNDNNSC"/>
    <dbReference type="OrthoDB" id="347657at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050236">
        <property type="entry name" value="Ser_Thr_kinase_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356:SF163">
        <property type="entry name" value="3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 12" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="35"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="211"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="426"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="215"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG96267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="529" mass="62944" checksum="2E0549248FC0E2F2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ76</accession>
    <name>A0A1J1GZ76_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Pre-mRNA-processing factor 17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00534300</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530566.1">
        <property type="nucleotide sequence ID" value="XM_028674188.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ76"/>
    <dbReference type="GeneID" id="39733876"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00534300"/>
    <dbReference type="OMA" id="TLWHPHE"/>
    <dbReference type="OrthoDB" id="10257301at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000034">
        <property type="entry name" value="Pre-mRNA-processing factor 17, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032847">
        <property type="entry name" value="PRPF17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43979">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43979:SF1">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="2 9" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="317"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="361"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="445"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="9">
        <location>
            <begin position="577"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="25"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="25"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00068146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG97765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="610" mass="71387" checksum="32C4AB7D86A2A924" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZI4</accession>
    <name>A0A1J1GZI4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Longevity-assurance (LAG1) protein, putative</fullName>
            <ecNumber evidence="8">2.3.1.24</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00029300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.24" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530657.1">
        <property type="nucleotide sequence ID" value="XM_028674289.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZI4"/>
    <dbReference type="GeneID" id="39728816"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00029300"/>
    <dbReference type="OMA" id="IFAKRCI"/>
    <dbReference type="OrthoDB" id="537032at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050291">
        <property type="term" value="F:sphingosine N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016439">
        <property type="entry name" value="Lag1/Lac1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560:SF0">
        <property type="entry name" value="LD18904P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560">
        <property type="entry name" value="LONGEVITY ASSURANCE FACTOR 1 LAG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005225">
        <property type="entry name" value="LAG1_LAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4 5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="5"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="301"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="7">
        <location>
            <begin position="117"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="352" mass="41807" checksum="BCDA0C5208C355DD" modified="2017-02-15" version="1">MKLDTVFKILLLVVIIFTIQQLWPLKEIKDVFKNESFVLLIKRILKKLQNFDFIFIKNELLTFYNEKYIVPKPSYFIFFGISGCLTFIVKFILNKLSQPIGEKLIPQKKWSQRIRKIKIQRFNIMFFNLFYFSLISAFGFVALRNQTYFPSELGGKGKLSDYFVDYPNQKTSNLIHLYYFLNGGYLLTSVYSILISEKLPDFYENLLQHLCAIILVYFSYSQNFIRVGAIIMLCHDICEIFSSACRVFVDTRYKFITVTSFCILFTSWGFLRLYIFAKRCILAIHRNFHIFSSLLNVETRIWLIFLLLVILLMNAYWFVLMAKMFIHFITSGQTEDILTRVTEIEEKEKKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZJ6</accession>
    <name>A0A1J1GZJ6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Importin-7, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00046100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530827.1">
        <property type="nucleotide sequence ID" value="XM_028674479.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZJ6"/>
    <dbReference type="GeneID" id="39728986"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00046100"/>
    <dbReference type="OMA" id="FALHSRI"/>
    <dbReference type="OrthoDB" id="760868at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997:SF60">
        <property type="entry name" value="IMPORTIN N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997">
        <property type="entry name" value="IMPORTIN-7, 8, 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="5">
        <location>
            <begin position="28"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1024"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1024"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1041"/>
            <end position="1050"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG98030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1186" mass="140110" checksum="AE26C7D41430A731" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZR5</accession>
    <name>A0A1J1GZR5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00040200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000121">
        <property type="protein sequence ID" value="CRG97967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530766.1">
        <property type="nucleotide sequence ID" value="XM_028674410.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZR5"/>
    <dbReference type="GeneID" id="39728926"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00040200"/>
    <dbReference type="OMA" id="MWCERLV"/>
    <dbReference type="OrthoDB" id="348930at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="282"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="375"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="483"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="682"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="811"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="393"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="483"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="497"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="529"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="551"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="599"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="707"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="820"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="832"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="832" mass="90694" checksum="8B57509A323CB792" modified="2017-02-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZW1</accession>
    <name>A0A1J1GZW1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sporozoite micronemal protein essential for cell traversal, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00059300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Apicomplexa</taxon>
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            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530955.1">
        <property type="nucleotide sequence ID" value="XM_028674620.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZW1"/>
    <dbReference type="GeneID" id="39729118"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00059300"/>
    <dbReference type="OMA" id="CPNDYSI"/>
    <dbReference type="OrthoDB" id="1366754at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020864">
        <property type="entry name" value="MACPF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01823">
        <property type="entry name" value="MACPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00457">
        <property type="entry name" value="MACPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51412">
        <property type="entry name" value="MACPF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="MACPF" evidence="3">
        <location>
            <begin position="246"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG98158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="858" mass="97237" checksum="68E2810B47957185" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZX7</accession>
    <name>A0A1J1GZX7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00061100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530971.1">
        <property type="nucleotide sequence ID" value="XM_028674638.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZX7"/>
    <dbReference type="GeneID" id="39729136"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00061100"/>
    <dbReference type="OrthoDB" id="371749at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="160"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="227" mass="27125" checksum="9ED74392654951F4" modified="2017-02-15" version="1">MTNSNKRKVNTKVSENEIIQKIDSINLKEVKDASASMNYYTNFLSLKFKKNREGIIYSMQRMKYLEGILKKLNKELLEGNKELEKLEKCIKDSDKVNTYLQKEIKKEIDKGNMYKSRVSLLKKNKIRIIKAQDILDQDIYYMESRINMMKQNADVNNKKVRKILNDKDKMHEEMEKFKKERKSLQYHLNNTKQDHEVLKNKMQNFILNMKKSKTEDEKLIIRNISSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZY0</accession>
    <name>A0A1J1GZY0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00057100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530933.1">
        <property type="nucleotide sequence ID" value="XM_028674596.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729096"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00057100"/>
    <dbReference type="OMA" id="DNNEQNE"/>
    <dbReference type="OrthoDB" id="392925at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="469"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2008"/>
            <end position="2097"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="799"/>
            <end position="1390"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1451"/>
            <end position="1496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="469"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2008"/>
            <end position="2049"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2056"/>
            <end position="2097"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2699" mass="324654" checksum="B6BF654264AB1FB5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H004</accession>
    <name>A0A1J1H004_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Programmed cell death protein 2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00031600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530680.1">
        <property type="nucleotide sequence ID" value="XM_028674315.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H004"/>
    <dbReference type="GeneID" id="39728839"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00031600"/>
    <dbReference type="OMA" id="YKGKFLY"/>
    <dbReference type="OrthoDB" id="366284at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052815">
        <property type="entry name" value="PDCD2-like_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007320">
        <property type="entry name" value="PDCD2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46421">
        <property type="entry name" value="PROGRAMMED CELL DEATH PROTEIN 2-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46421:SF1">
        <property type="entry name" value="PROGRAMMED CELL DEATH PROTEIN 2-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04194">
        <property type="entry name" value="PDCD2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Programmed cell death protein 2 C-terminal" evidence="1">
        <location>
            <begin position="323"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="433" mass="51477" checksum="99A6DB099CBC420B" modified="2017-02-15" version="1">MYIGVLSDEIDDNFDLKNDSKFGGDPLWLCGKEPANIHLKCTICKKDLIFLFQLSTSYDEYIRIIYIFCCVNSTKCNMDKRNWVCIKAKKKLLDNSEYKKIEDKNGLNMHEVCSDKNIKINRYCSTSSKKIEDNGKTTFSFSGENTEKEDVFQEKIICRKEKLIDWNSLFSKSVKDEKSNIPLFNYSINKSLNYVNQKNENNHNINSNNINTYETYYDKSYDLINSKITFDNKKELNKCYKMNHENVNIIPSNDSKLPSYYIYLVEDDEEYDKDYLYEKAKKMYEMYEHNKHILEHEECNNEGNDDIDNNEESFENDFNGCIKFYSYLSKNYNQILRYSYKGKFLYMHKQTKNYLKGKNMLCAHCKSKLVFELQFFSTFIYQIEKKLQNKENNVLKNIINNFSVGNVIIFSCEMDCVSIDDIYSYEHIELEIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0E8</accession>
    <name>A0A1J1H0E8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">U4/U6 snRNA-associated-splicing factor, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00433800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529560.1">
        <property type="nucleotide sequence ID" value="XM_028673070.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0E8"/>
    <dbReference type="GeneID" id="39732870"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00433800"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006509">
        <property type="entry name" value="RBM39_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48036">
        <property type="entry name" value="SPLICING FACTOR (PAD-1), PUTATIVE (AFU_ORTHOLOGUE AFUA_1G15810)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="175"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="382"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="17"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="49"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="62"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="538" mass="64138" checksum="9458397D94D8AABE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0Q7</accession>
    <name>A0A1J1H0Q7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00469500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529917.1">
        <property type="nucleotide sequence ID" value="XM_028673468.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733228"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00469500"/>
    <dbReference type="OMA" id="NSKSIFM"/>
    <dbReference type="OrthoDB" id="372999at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="80"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="294"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="332"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="781"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="936"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1681"/>
            <end position="1714"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1769"/>
            <end position="1820"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="878"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="94"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="134"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="180"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="297"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="347"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="415"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="465"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="503"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="524"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="781"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="821"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="840"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="936"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="970"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1769"/>
            <end position="1794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1800"/>
            <end position="1809"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1901" mass="222965" checksum="A433CBC2EBDABA04" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0V4</accession>
    <name>A0A1J1H0V4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00474100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000087">
        <property type="protein sequence ID" value="CRG97162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529965.1">
        <property type="nucleotide sequence ID" value="XM_028673520.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0V4"/>
    <dbReference type="GeneID" id="39733274"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00474100"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="407"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1009" mass="123950" checksum="0BBD72B6882D5ED0" modified="2017-02-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0W3</accession>
    <name>A0A1J1H0W3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ras-related protein Rab-18, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00052800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530890.1">
        <property type="nucleotide sequence ID" value="XM_028674549.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0W3"/>
    <dbReference type="GeneID" id="39729053"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00052800"/>
    <dbReference type="OMA" id="RVHKMDV"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01863">
        <property type="entry name" value="Rab18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001312">
        <property type="entry name" value="Ras-related protein Rab-18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050305">
        <property type="entry name" value="Small_GTPase_Rab"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47980">
        <property type="entry name" value="LD44762P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0488">Methylation</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0636">Prenylation</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG98093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="201" mass="23314" checksum="D491390C6975AE43" modified="2017-02-15" version="1">MKNKNKYDYLLKLLLVGDSSVGKSSILCRYSDNQFEEKVLSTIGIDFKVKYLRIDNKTIKVGIWDTAGQERFRTLTSAYYRNAHAIILVYDCTVRESFENLDVWINEIDKYSTNKNAIKMLVANKIDKPNHEVTKSEGKNFAFENNMLFCETSAKNDINITYCFEELIQQILNNPSLLELSFVTKNFKLGRKEENRSNCVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1B9</accession>
    <name>A0A1J1H1B9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00468200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529904.1">
        <property type="nucleotide sequence ID" value="XM_028673453.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1B9"/>
    <dbReference type="GeneID" id="39733215"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00468200"/>
    <dbReference type="OMA" id="ICDFGSH"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000748">
        <property type="entry name" value="NAK protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22967:SF57">
        <property type="entry name" value="AUXILIN, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22967">
        <property type="entry name" value="SERINE/THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="24"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG97101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="682" mass="79926" checksum="E4C3B9553FC0466E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1P4</accession>
    <name>A0A1J1H1P4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Deoxyribose-phosphate aldolase, putative</fullName>
            <ecNumber evidence="3">4.1.2.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00480800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.4" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530032.1">
        <property type="nucleotide sequence ID" value="XM_028673595.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1P4"/>
    <dbReference type="GeneID" id="39733341"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00480800"/>
    <dbReference type="OMA" id="RYSGPDY"/>
    <dbReference type="OrthoDB" id="70823at2759"/>
    <dbReference type="UniPathway" id="UPA00002">
        <property type="reaction ID" value="UER00468"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004139">
        <property type="term" value="F:deoxyribose-phosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009264">
        <property type="term" value="P:deoxyribonucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046386">
        <property type="term" value="P:deoxyribose phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011343">
        <property type="entry name" value="DeoC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002915">
        <property type="entry name" value="DeoC/FbaB/LacD_aldolase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00126">
        <property type="entry name" value="deoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10889">
        <property type="entry name" value="DEOXYRIBOSE-PHOSPHATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10889:SF1">
        <property type="entry name" value="DEOXYRIBOSE-PHOSPHATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01791">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001357">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01133">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0704">Schiff base</keyword>
    <feature type="active site" description="Schiff-base intermediate with acetaldehyde" evidence="2">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001357-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="263" mass="29179" checksum="FD89EA26708408BE" modified="2017-02-15" version="1">MSNYTETFAAWTTICLTDHTQLGENDKEDDIREVCKEAVKTCPYAAAVCVYPKFVKFINEKIKKEIDPFKPQIACVINFPHGTDSIEKVVEDTKKAIEDGADEIDLVINYKKILENVDEGLKEATELTKLVKEVLKNKLLKVIIEVGELKTDDLIIKTTLAVLEGNADFVKTSTGKVKINATPSSVKAIIKAFKQHIEKHPEKKDKIGIKVAGGVGDLNLASYYILLARTCFGSLACHPNNFRIGSSSLVPKLRKIIEQCPIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1P9</accession>
    <name>A0A1J1H1P9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ZIP domain-containing protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ZIPCO</name>
        <name evidence="6" type="ORF">PGAL8A_00481600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530040.1">
        <property type="nucleotide sequence ID" value="XM_028673604.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1P9"/>
    <dbReference type="GeneID" id="39733349"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00481600"/>
    <dbReference type="OMA" id="IFIECVA"/>
    <dbReference type="OrthoDB" id="448280at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040:SF198">
        <property type="entry name" value="METAL HOMEOSTASIS FACTOR ATX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040">
        <property type="entry name" value="ZINC/IRON TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="254"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="287"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="313" mass="35442" checksum="930F4F65165C3A66" modified="2017-02-15" version="1">MWLTAFLALLIFIECVAVIYIPSYIENKLSKIKKSRFMNMENFENIASGAILSLAFIHMLPEAIILSNKKNINLYNIFTLILVSIAFLNITDILYDHDLENSFDINGTQVCENQSNSIKNIDDKGDNTNYVDGNASEDIDIEMKALDGKAKNDSCKNNFFFDMFKSNSFFIVLSLFIHSFIEGLLMGSLKDKNAVVIVGLSMIAHKWAECLIVYKNVVSKIENKILATIYAWSFILSLPLGVFIAIFSFPSNELVEIIFSSIACGFFLYLSFNMTKDIRITKNNKHFISFSYFLGVCGMSGLMLVFNSFEETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H317</accession>
    <name>A0A1J1H317_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">KHDC4/BBP-like KH-domain type I domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00031200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530676.1">
        <property type="nucleotide sequence ID" value="XM_028674311.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728835"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00031200"/>
    <dbReference type="OMA" id="SRNCINS"/>
    <dbReference type="OrthoDB" id="5989967at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22386">
        <property type="entry name" value="KH-I_KHDC4_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.10:FF:000070">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055256">
        <property type="entry name" value="KH_1_KHDC4/BBP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047889">
        <property type="entry name" value="KHDC4_KH-I_second"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031121">
        <property type="entry name" value="RIK/BLOM7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15744">
        <property type="entry name" value="BLOM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15744:SF0">
        <property type="entry name" value="KH HOMOLOGY DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22675">
        <property type="entry name" value="KH-I_KHDC4-BBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KHDC4/BBP-like KH-domain type I" evidence="2">
        <location>
            <begin position="2323"/>
            <end position="2396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1014"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1785"/>
            <end position="1915"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2067"/>
            <end position="2144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="213"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="249"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1014"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1084"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1785"/>
            <end position="1798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1825"/>
            <end position="1915"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2068"/>
            <end position="2141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2444" mass="285110" checksum="4C25FF447CA7941A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3I9</accession>
    <name>A0A1J1H3I9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Heat shock protein 110, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">HSP110c</name>
        <name evidence="4" type="ORF">PGAL8A_00049000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530852.1">
        <property type="nucleotide sequence ID" value="XM_028674506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3I9"/>
    <dbReference type="GeneID" id="39729015"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00049000"/>
    <dbReference type="OMA" id="KEYECIE"/>
    <dbReference type="OrthoDB" id="434160at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11732">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSP105-110-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639:SF4">
        <property type="entry name" value="HSC70CB, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45639">
        <property type="entry name" value="HSC70CB, ISOFORM G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="534"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="797"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="534"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="560"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="797"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="838"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="853"/>
            <end position="865"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG98055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="865" mass="99662" checksum="5206F82B2EFE8AEB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2012-05-16" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>H7CDY0</accession>
    <name>H7CDY0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpl36</name>
        <name evidence="6" type="synonym">RPL36</name>
        <name evidence="6" type="ORF">PGAL8A_API02400</name>
    </gene>
    <organism evidence="5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <geneLocation type="apicoplast" evidence="5"/>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2012" name="Mol. Biol. Evol." volume="29" first="2095" last="2099">
            <title>The Plasmodium Apicoplast Genome: Conserved Structure and Close Relationship of P. ovale to Rodent Malaria Parasites.</title>
            <authorList>
                <person name="Arisue N."/>
                <person name="Hashimoto T."/>
                <person name="Mitsui H."/>
                <person name="Palacpac N.M.Q."/>
                <person name="Kaneko A."/>
                <person name="Kawai S."/>
                <person name="Hasegawa M."/>
                <person name="Tanabe K."/>
                <person name="Horii T."/>
            </authorList>
            <dbReference type="PubMed" id="22396524"/>
            <dbReference type="DOI" id="10.1093/molbev/mss082"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">A8</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL36 family.</text>
    </comment>
    <dbReference type="EMBL" id="AB649424">
        <property type="protein sequence ID" value="BAL70750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LN835293">
        <property type="protein sequence ID" value="CRG98239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009325466.1">
        <property type="nucleotide sequence ID" value="NC_031963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="H7CDY0"/>
    <dbReference type="SMR" id="H7CDY0"/>
    <dbReference type="GeneID" id="30315794"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_API02400"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Apicoplast API"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000473">
        <property type="entry name" value="Ribosomal_bL36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035977">
        <property type="entry name" value="Ribosomal_bL36_sp"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01022">
        <property type="entry name" value="rpmJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42888">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L36, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42888:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL36C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00444">
        <property type="entry name" value="Ribosomal_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57840">
        <property type="entry name" value="Ribosomal protein L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00828">
        <property type="entry name" value="RIBOSOMAL_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0933">Apicoplast</keyword>
    <keyword evidence="5" id="KW-0934">Plastid</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAL70750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG98239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="36" mass="4396" checksum="5E25D7CA496E80AA" modified="2012-05-16" version="1">MKKRSSIKKICNKCKLIKRFKKLHIICINKKHKQTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKZ6</accession>
    <name>A0A1J1GKZ6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cell cycle regulator protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00076800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525884.1">
        <property type="nucleotide sequence ID" value="XM_028670066.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKZ6"/>
    <dbReference type="GeneID" id="39729293"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00076800"/>
    <dbReference type="OMA" id="WEYGDDY"/>
    <dbReference type="OrthoDB" id="10249667at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001731">
        <property type="term" value="P:formation of translation preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11609">
        <property type="entry name" value="MCT1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21155">
        <property type="entry name" value="PUA_MCTS-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.400.20:FF:000001">
        <property type="entry name" value="Malignant T-cell-amplified sequence 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.400.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016437">
        <property type="entry name" value="MCT-1/Tma20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041366">
        <property type="entry name" value="Pre-PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004521">
        <property type="entry name" value="Uncharacterised_CHP00451"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00451">
        <property type="entry name" value="unchar_dom_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22798:SF0">
        <property type="entry name" value="MALIGNANT T-CELL-AMPLIFIED SEQUENCE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22798">
        <property type="entry name" value="MCT-1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17832">
        <property type="entry name" value="Pre-PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01472">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005067">
        <property type="entry name" value="Tma_RNA-bind_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50890">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PUA" evidence="4">
        <location>
            <begin position="91"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR005067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="180" mass="20373" checksum="91DD0FD498128ACE" modified="2017-02-15" version="1">MKSFSIDNISSQNLMKSSVQRSIKATILKDYPKLEDYIENIFPKKGSLFLGKCINHVTVIIGNQELLFFQIRNGPWIPSLKLVHKYPFMMPKIQVDKGAVKHVLRGSNIMCPGVTSPGGKLEEEVEANKVIQITAENKEYACAVGITTMSTKEIVEKNKDICIENIHYLNDGLWNFKIEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLB9</accession>
    <name>A0A1J1GLB9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Memo-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00091000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MEMO1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526028.1">
        <property type="nucleotide sequence ID" value="XM_028671666.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLB9"/>
    <dbReference type="GeneID" id="39729434"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00091000"/>
    <dbReference type="OMA" id="IIAHAGY"/>
    <dbReference type="OrthoDB" id="417112at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07361">
        <property type="entry name" value="MEMO_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.830.10">
        <property type="entry name" value="LigB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002737">
        <property type="entry name" value="MEMO1_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR04336">
        <property type="entry name" value="AmmeMemoSam_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11060">
        <property type="entry name" value="PROTEIN MEMO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11060:SF0">
        <property type="entry name" value="PROTEIN MEMO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01875">
        <property type="entry name" value="Memo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="228" mass="26618" checksum="6CA2A8EDCE4EF44B" modified="2017-02-15" version="1" fragment="single">KNIFIAGPNHHIYNNKCLLPKVDKYETPFGFLEINNDIISDIMKNDSYNLYDFIDEVDDEEEHSIEMQLPLIKYIIKDKDIKIIPIYVGCIGNDIEKIKLICNPLKKYFENDDNLFLFSSDFCHYGARFNFTNILQKYNDKYIYKQIENMDKDAINIISNHDITGFIHYLNKTRNTICGSNPIKIMLNLLQNYSGNILTKLMHYSQSNHVKNMNDSSVSYAGIVSFIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLC3</accession>
    <name>A0A1J1GLC3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00086500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525983.1">
        <property type="nucleotide sequence ID" value="XM_028671166.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLC3"/>
    <dbReference type="GeneID" id="39729389"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00086500"/>
    <dbReference type="OrthoDB" id="371010at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd17039">
        <property type="entry name" value="Ubl_ubiquitin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="296"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="62"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="347" mass="41949" checksum="8F5220143DB50611" modified="2017-02-15" version="1">MIFKLNFINFILFNFFLTYICRSIKLHDRNKLTKNNFMSISNIPIKTIRNKNNSKENDTRKYKIMINYYNKSNIFQKSFFLSVSEDTNIKDLKKKIETLHGIPTEFQEVLYENKSLSDHLIIKNLIEDKKIKLLNFRLIPILPHIFNEETNDEHEKENKKIKNLKDKLKYFGYITMLNEYKKLLKKLEEKKYIIKGVDIIESFNSFDKEFEKILKNNNINLEKIKKEIDDLKFVDKKKLLLRLQVDYPLMSNLLLDRIKQLIQFYYLGDVKSVIKFSIFFYILYKYANYPRNIKTFFLYLSIFTLIAPCKYFYKIMHFLFFFVPQDILFSGFTNVLSAPYQQILMCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLD3</accession>
    <name>A0A1J1GLD3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00092800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526046.1">
        <property type="nucleotide sequence ID" value="XM_028671866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLD3"/>
    <dbReference type="GeneID" id="39729452"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00092800"/>
    <dbReference type="OMA" id="FEDMTHD"/>
    <dbReference type="OrthoDB" id="1861185at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033065">
        <property type="term" value="C:Rad51C-XRCC3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005657">
        <property type="term" value="C:replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000400">
        <property type="term" value="F:four-way junction DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045003">
        <property type="term" value="P:double-strand break repair via synthesis-dependent strand annealing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071140">
        <property type="term" value="P:resolution of mitotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090656">
        <property type="term" value="P:t-circle formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000722">
        <property type="term" value="P:telomere maintenance via recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46487">
        <property type="entry name" value="DNA REPAIR PROTEIN XRCC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46487:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN XRCC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="322" mass="38482" checksum="9BA9B4B1EA26E713" modified="2017-02-15" version="1">MNISNCRSVEKIFDDSTFNKIERKKLEFDNKKLNNFFENGIINYSLVEIIGNCGSGKTQFALTLCAEHLLKIFDINKNINDLNLKNKENIIFYIYINRMFPIHRLIEIIEKKIQEKENNQNKCYVYEDIFKDNNLHNNTTRKNNSNNNCSSKNSFDEKQFNYSFKRDLRGILRNLYIQKINDEKDLFILFEKDIFYILKYYKISLLIIDSINSIFNANQKLDNYKKNQLFIKISLILKKISYENNFFVLLINSLYIKKEYNDFSFNIADFIISSSCANTILFFKKIKKKNEIIRKIIIHYSEFLSKYKTLKFEITDTGFNVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLG5</accession>
    <name>A0A1J1GLG5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00095200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526068.1">
        <property type="nucleotide sequence ID" value="XM_028672110.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLG5"/>
    <dbReference type="GeneID" id="39729476"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00095200"/>
    <dbReference type="OrthoDB" id="390933at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="1">
        <location>
            <begin position="564"/>
            <end position="625"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="781" mass="94290" checksum="CF87F75C42C51631" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLJ0</accession>
    <name>A0A1J1GLJ0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sentrin-specific protease 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00077900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525899.1">
        <property type="nucleotide sequence ID" value="XM_028670233.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729304"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00077900"/>
    <dbReference type="OMA" id="INENRMH"/>
    <dbReference type="OrthoDB" id="442460at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016926">
        <property type="term" value="P:protein desumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.130">
        <property type="entry name" value="Ubiquitin-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46915:SF2">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46915">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEASE 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50600">
        <property type="entry name" value="ULP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="7">
        <location>
            <begin position="1198"/>
            <end position="1545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="877"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="583"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="877"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1049"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1063"/>
            <end position="1077"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1653" mass="197826" checksum="907DE80E91774AC4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLJ4</accession>
    <name>A0A1J1GLJ4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein SOC1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00091600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SAPS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526034.1">
        <property type="nucleotide sequence ID" value="XM_028671732.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLJ4"/>
    <dbReference type="GeneID" id="39729440"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00091600"/>
    <dbReference type="OrthoDB" id="295029at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019903">
        <property type="term" value="F:protein phosphatase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007587">
        <property type="entry name" value="SAPS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12634:SF8">
        <property type="entry name" value="FIERY MOUNTAIN, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12634">
        <property type="entry name" value="SIT4 YEAST -ASSOCIATING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="316"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="531"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="353"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="324"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="531"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="556"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1149" mass="136547" checksum="69E59C9F401E42C6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLL3</accession>
    <name>A0A1J1GLL3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Cation transporting ATPase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PGAL8A_00097100</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526087.1">
        <property type="nucleotide sequence ID" value="XM_028672322.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729495"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00097100"/>
    <dbReference type="OMA" id="QKTKYVW"/>
    <dbReference type="OrthoDB" id="48943at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015662">
        <property type="term" value="F:P-type ion transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006544">
        <property type="entry name" value="P-type_TPase_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630">
        <property type="entry name" value="CATION-TRANSPORTING ATPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630:SF7">
        <property type="entry name" value="ENDOPLASMIC RETICULUM TRANSMEMBRANE HELIX TRANSLOCASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="21"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="150"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="437"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="462"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="659"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="698"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1393"/>
            <end position="1412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1424"/>
            <end position="1442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1454"/>
            <end position="1478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1506"/>
            <end position="1525"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1537"/>
            <end position="1563"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1575"/>
            <end position="1598"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="13">
        <location>
            <begin position="499"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1089"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="82"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="1281"/>
            <end position="1308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="362"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1089"/>
            <end position="1106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG93265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1610" mass="188411" checksum="3C30AC5D6A6C2640" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLT7</accession>
    <name>A0A1J1GLT7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cleavage and polyadenylation specificity factor subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00105100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Nudix hydrolase family. CPSF5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526167.1">
        <property type="nucleotide sequence ID" value="XM_028673210.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLT7"/>
    <dbReference type="GeneID" id="39729576"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00105100"/>
    <dbReference type="OMA" id="NDEWEIG"/>
    <dbReference type="OrthoDB" id="277288at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005849">
        <property type="term" value="C:mRNA cleavage factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016706">
        <property type="entry name" value="Cleav_polyA_spec_factor_su5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13047">
        <property type="entry name" value="PRE-MRNA CLEAVAGE FACTOR IM, 25KD SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13869">
        <property type="entry name" value="NUDIX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017888">
        <property type="entry name" value="CPSF-25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR017888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="231" mass="27352" checksum="C6277BAACDCBE0FA" modified="2017-02-15" version="1">MVIQSTNSNINTTNINICNRENKSEWLLYPQSNYEFNIDEKLKNKFIIDNEKCKKRINSYNKNGIRNSVLAIILCHRYEYPHLLLLQHLESQKYYLLNGKYKTWEKPKEVLKKKLQKYINKIKDIHFITNQINSEKEETVEIGEFLGEWWKTQFNSVYLPYLPAHVTRPKEYVRLYQVTLSSKCIFHLPPGFTLKALPLFDLNNCGLAINGLSSILSRFKLHCMVQEESEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLW0</accession>
    <name>A0A1J1GLW0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Golgi organization and biogenesis factor, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00091700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CSN7/EIF3M family. CSN7 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526035.1">
        <property type="nucleotide sequence ID" value="XM_028671743.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLW0"/>
    <dbReference type="GeneID" id="39729441"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00091700"/>
    <dbReference type="OMA" id="VCLKALW"/>
    <dbReference type="OrthoDB" id="10267031at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002183">
        <property type="term" value="P:cytoplasmic translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045237">
        <property type="entry name" value="COPS7/eIF3m"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15350">
        <property type="entry name" value="COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15350:SF2">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="2">
        <location>
            <begin position="226"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="429" mass="50790" checksum="23AEFDA3D81DA055" modified="2017-02-15" version="1">MSVYIQLTHDISGTVTAVTIGDWILGILKQKNIQEYEVFFKKFLNIYQKQDKESESNNRSEIFSLLLSASDFVFETLVETKKNNKIKVIIDNKESVKSFNEFYKEVEEYFVILISILQLEFKSVEDLNNATNNFIKAIKNYNVFPELRLKILQLLYNSFSVNFSFRFPTFIAILQFSSQNNIFHNILPYIKFIDQWIKEWNISSREKRQIYLIIAQELKKLKKYEDSFKHLKKHIYYFQKESEEILNHPNTINASVELIVDSINLNSNIYFHEILNLDAIQNLQNIKEHQPLFELLVIFYKYGIHEFLTFKNTYGVDFFEKYNINLEACENKIYLLSIISLFKDIKIQNIQYISEKLNITPLKIEQILVAAIGSGVIDAKIDQINKTIQMKTTILRHFDDTHWELLNNQINKYINNVQKILDLTSQTKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM22</accession>
    <name>A0A1J1GM22_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nucleoside transporter 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00117600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526292.1">
        <property type="nucleotide sequence ID" value="XM_028674599.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM22"/>
    <dbReference type="GeneID" id="39729701"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00117600"/>
    <dbReference type="OMA" id="RTYDICF"/>
    <dbReference type="OrthoDB" id="375960at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="163"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="229"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="393"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="467"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="492"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="570" mass="66375" checksum="6C8B85BCF13339F6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM47</accession>
    <name>A0A1J1GM47_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Folate transporter 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00121900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526334.1">
        <property type="nucleotide sequence ID" value="XM_028674732.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM47"/>
    <dbReference type="GeneID" id="39729744"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00121900"/>
    <dbReference type="OMA" id="MTGRLKW"/>
    <dbReference type="OrthoDB" id="754047at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd17484">
        <property type="entry name" value="MFS_FBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585:SF0">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03092">
        <property type="entry name" value="BT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="187"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="301"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="327"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="358"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="395"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="433"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="498" mass="56594" checksum="9E535E780A30AE85" modified="2017-02-15" version="1">MEQQDNDFLKKKDSYETCSTGTIASYSSYNENSHLIEKKIIDQDYVNVDSIFNKMSSSLIAMLQGVEVLCNFSILFLFKDNYKLDPASLSVVMSLIKIPWSVKLIWAILSDSYPIFGYRRKYYLLLGSLSCIISLITLGLINHTNIILTICLLIIFFFGSSLCNVIGEAQVVESSRKGSISNSAKNISAFFAFRKLSFALMSYLSGFLLSIMNKQHIFLVGSFLPICVFVSAFFILEKKNCKKTCVKEQMKCIYDILKIPYIKNFIIYIFIMMSTPSCGSTLFFFMTNELKFGVQLLGKMAMFQSVASLIAILFYMLFFSKVDIGKLLFYSTIIITPFCLLPLVVVNKLNNYLYIPDSVFIITDTILIEFIGEFQTIPLLVLCSRVTPEGLESTIYSLLLSANNLALIISSFFSSLLTYVLGITSTNFKNLSLMIIICCLTNLIPLFFMYILPNFNNKDLHKYKDPCENISYEITDYVSSKSSEQNEKKNTSEEIQIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM53</accession>
    <name>A0A1J1GM53_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Prolyl 4-hydroxylase subunit alpha, putative</fullName>
            <ecNumber evidence="7">1.14.11.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00122700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.2" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526342.1">
        <property type="nucleotide sequence ID" value="XM_028674741.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM53"/>
    <dbReference type="GeneID" id="39729752"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00122700"/>
    <dbReference type="OMA" id="YCINRIK"/>
    <dbReference type="OrthoDB" id="407973at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF246">
        <property type="entry name" value="TRANSMEMBRANE PROLYL 4-HYDROXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prolyl 4-hydroxylase alpha subunit" evidence="6">
        <location>
            <begin position="126"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="442" mass="51886" checksum="EE1B3593D9111A40" modified="2017-02-15" version="1">MELKKIVKNSNDNYNYSDQNKKTTKIEINDKEEFRYIKKGEILQSNEIQEEKDEFGITLYDNEIKYSDDIQTIVKKVINGKNIDFYKKYSSYLLYLSNEMENNEIDENKANDDNTKTFFKIKLNPQNMCIIYNVVDKRTIEKILSLCNNKYKKSKTSIGYITDKQENYKITNSLNRTSSTVFLYTIRSRSIIEENQIECDSSIVYTKDESIIELENTICNLVKIPLCYLEPLAIVKYEENNYFNLHHDGSFRRATLLIYLNDVNKDGETVFPYYNLSIKPIQGSAIFWYNNIPLEDEYAITYCINRIKKIDEKEKLICEQNSEGKDNTYSINDKQNIKISCFSKTEKSSLHLHNATEDNFIAKNLSVTDSNENKNYIKNTVDLINFLNEKSNLQKYSIDLVKDELGNTYISDMTMIHQANKVTKECKYVINCFFNINIVRNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMF5</accession>
    <name>A0A1J1GMF5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00132900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526446.1">
        <property type="nucleotide sequence ID" value="XM_028674857.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMF5"/>
    <dbReference type="GeneID" id="39729854"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00132900"/>
    <dbReference type="OrthoDB" id="375145at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012610879" evidence="1">
        <location>
            <begin position="21"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="187" mass="22608" checksum="27005E543666BB3D" modified="2017-02-15" version="1">MKYVSLFLFLFFLIISICFCVKDNEQKDNALFLKDNNTTESTVVKNKLINEIKKKSNEIRNMYNNLNIKNKKLPLYIFIIDKNEKKRQMLKDLFLKGKLDFLQGNNTPFSKYYISKKNKNILDRITLQNKINDEEKFLNSLNKEDKKKYIKRKLQEYEYLRNNVNQLSLNIENKFDSLEKLMMYIKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMM2</accession>
    <name>A0A1J1GMM2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Mitochondrial chaperone BCS1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PGAL8A_00131700</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family. BCS1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526434.1">
        <property type="nucleotide sequence ID" value="XM_028674843.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMM2"/>
    <dbReference type="GeneID" id="39729842"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00131700"/>
    <dbReference type="OMA" id="NICCINI"/>
    <dbReference type="OrthoDB" id="10251412at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034551">
        <property type="term" value="P:mitochondrial respiratory chain complex III assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd19510">
        <property type="entry name" value="RecA-like_BCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000768">
        <property type="entry name" value="Probable mitochondrial chaperone bcs1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057495">
        <property type="entry name" value="AAA_lid_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014851">
        <property type="entry name" value="BCS1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050747">
        <property type="entry name" value="Mitochondrial_chaperone_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23070">
        <property type="entry name" value="BCS1 AAA-TYPE ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25426">
        <property type="entry name" value="AAA_lid_BCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08740">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01024">
        <property type="entry name" value="BCS1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="BCS1 N-terminal" evidence="14">
        <location>
            <begin position="50"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="13">
        <location>
            <begin position="249"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG93612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="468" mass="54514" checksum="E40CD7D7BC3A188E" modified="2017-02-15" version="1">MQKFLMNKNSENNGEKCIIDSKIDENCGFFESIFKNITKNEYFSAGVGIISVGAFVTVANRLNSLFYQTLKKNMFTSLEITINDTSYYWILEYIVKKGIISRHLSLKTQMVNEKNKKNVFFSFLPSIGNHLLIYENKLIFVERYREKNMVSDMNRSIPFENIKLSTFIWSKHIFEKILRDAKLYIDKKEEGKTLVYKTFGHEWRPFGTPKNKRPINSVILPKDLSEYIINDIEKFLNSSNWYIDKGIPYRRCYLLYGPPGCGKSSLITALAGYFDFNLCTININDIYLTDDRFIHLLATVPPKTILILEDIDFIFVNSINKDENKNVSSSLSSTSIFNNPVKTLGVSYSGLLNALDGIVATEERIIFMTTNNIERLPNTLIRPGRVDMKILIPYANNYQYEKMFLRFFPEHHDLAKKFSKIFQNFHLSMAEIQSFFLFSKVDPYKTIKNAEDWVNSYKEKKTNDKINT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMS2</accession>
    <name>A0A1J1GMS2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cyclin dependent kinase binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00134000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526457.1">
        <property type="nucleotide sequence ID" value="XM_028674869.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMS2"/>
    <dbReference type="GeneID" id="39729865"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00134000"/>
    <dbReference type="OMA" id="CLSYKPY"/>
    <dbReference type="OrthoDB" id="5353095at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20556">
        <property type="entry name" value="CYCLIN_CABLES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000087">
        <property type="entry name" value="Putative Cyclin dependent kinase binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012388">
        <property type="entry name" value="CABLES1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22896">
        <property type="entry name" value="CDK5 AND ABL1 ENZYME SUBSTRATE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22896:SF0">
        <property type="entry name" value="CYCLIN N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF025798">
        <property type="entry name" value="Cables"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="461" mass="54796" checksum="4F33019264FB082E" modified="2017-02-15" version="1">MKKINYFSIYEDFFKDANNFLNTIETKNNFFDYSSESSADNKNERNDCTNNKNGEYADFYINVESNKVTFKSDLLENEKKKNNNNYTNIKFSSRILLCYKNTHSLCLSYKPYNENTCNDSSNVNNSISILKKKNSNFDDKGEEYNLKKKNENKILNFLYKWILPLKKDDANVLKETKKKIKNKDIITKKVDDERNIHSDKKKKKFYNLNNNNLNITTKKTEENIKKDQNINEIKKRKKGKKGISYEHLLKPSRYDYDAFCLFNPRFKQGKHHTVMYLQSYNVSIIPFVKPKKLKEKVNELFSEINPWIHKSLTLSKLRNLKIDLFNLINFIPEIDISTISCAWVFFERLVIKGYVHKFNRKLYAATCLILSLKFYQHDDIQILEKLLSYIQKLDKKENLTPSLIFSVEFLVYRLLDFSLQHTYENIRPHIHQYLESKELKFEDVYGISEDAYLCSNYASKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMS4</accession>
    <name>A0A1J1GMS4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00145000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526566.1">
        <property type="nucleotide sequence ID" value="XM_028674990.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMS4"/>
    <dbReference type="GeneID" id="39729974"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00145000"/>
    <dbReference type="OMA" id="FNRIGSN"/>
    <dbReference type="OrthoDB" id="386653at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="49"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="171"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="66"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="97"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="266" mass="31018" checksum="006AAC0B0574729D" modified="2017-02-15" version="1">MEEAYAGSCVQSLFEPKVDFSICTNKSIKLFLKDLNSLNCSKNAIDNSNENKLNDINKSELNNNHNKNDNKNEKDVENNSLSKDEDKNLLNFENKDSLNSNNEKGTNNDNYKYATEENIKKMLDENLSLLNGYSYFNRIGHNINLLHTELSSVKKDFLFLSKQTRLKVKKLKNIKKKNIIYKGLLEEVKEERKRKEMYEKLSIEIQKLDDVRKIQKKQKAEKCSIENFEKKIKNIENTIISNNNNVLKTIEQINEIISTNLQTDIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMT8</accession>
    <name>A0A1J1GMT8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">peptidyl-tRNA hydrolase</fullName>
            <ecNumber evidence="1">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00139000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>an N-acyl-L-alpha-aminoacyl-tRNA + H2O = an N-acyl-L-amino acid + a tRNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54448"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:13883"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59874"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:138191"/>
            <dbReference type="EC" id="3.1.1.29"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526506.1">
        <property type="nucleotide sequence ID" value="XM_028674924.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMT8"/>
    <dbReference type="GeneID" id="39729914"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00139000"/>
    <dbReference type="OMA" id="AIIAQCC"/>
    <dbReference type="OrthoDB" id="201213at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:peptidyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02429">
        <property type="entry name" value="PTH2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1490.10">
        <property type="entry name" value="Bit1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023476">
        <property type="entry name" value="Pep_tRNA_hydro_II_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002833">
        <property type="entry name" value="PTH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042237">
        <property type="entry name" value="PTRHD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46194">
        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE PTRHD1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46194:SF1">
        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE PTRHD1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01981">
        <property type="entry name" value="PTH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102462">
        <property type="entry name" value="Peptidyl-tRNA hydrolase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00048707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="123" mass="14464" checksum="065801186A9314FB" modified="2017-02-15" version="1">MQENTIIQYILINKEILDKKWPLGSIIAQACHACVAVIAENIDDNIVKEYLSPENINNMHKVILKVENTEELKNLSSILDKESFKYKIWTEYPENILTALALKPYYKNTVRDYFKKYQLLKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMU1</accession>
    <name>A0A1J1GMU1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00128800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526403.1">
        <property type="nucleotide sequence ID" value="XM_028674809.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMU1"/>
    <dbReference type="GeneID" id="39729813"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00128800"/>
    <dbReference type="OMA" id="KTYRKDQ"/>
    <dbReference type="OrthoDB" id="386058at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="613"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="213"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="298"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="375"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="492"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="622"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="751" mass="89297" checksum="18843E0DC3E75D8C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN60</accession>
    <name>A0A1J1GN60_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00161300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526726.1">
        <property type="nucleotide sequence ID" value="XM_028675168.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN60"/>
    <dbReference type="GeneID" id="39730138"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00161300"/>
    <dbReference type="OMA" id="FDDKEHI"/>
    <dbReference type="OrthoDB" id="378604at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="268"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="363"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="461"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="565" mass="67890" checksum="F17AE722D39EA93B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN64</accession>
    <name>A0A1J1GN64_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00161100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526724.1">
        <property type="nucleotide sequence ID" value="XM_028675165.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN64"/>
    <dbReference type="GeneID" id="39730136"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00161100"/>
    <dbReference type="OMA" id="SKEINWF"/>
    <dbReference type="OrthoDB" id="370662at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="341" mass="40900" checksum="C6BF99C9FBEF23BC" modified="2017-02-15" version="1">MFLPKDEMLILHFTVHDVYDTNDNKITLEEKPYIKFYWKNIKYKNYLKFFSKEINWFCEFFLPYSLGDCIENLVVQIWASSYIKTKRKIAYNYININNVEKKSKINGKTELIGRRKGLKIIYSLQIMCYSLYKFMKSTQMLILDKISIYKMMQIHKKNEKSNYWLEKNNLFDKYLISLFEKKNYEKANTALRLKTIKTQKIKTKIKSNLKLKWKSKLKRKNKTKSKVSIKKSQLNLKNISSITKKNAKKTSKKKIKINVKPKDVDSNSKHKKYFLNIGYKIHKLAPKKTIKFFNFKFTLPDNENDILKTTTNCTSKNLAYPNFNKARCIYYLLKKIKKEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNG6</accession>
    <name>A0A1J1GNG6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">SNF2 helicase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ISWI</name>
        <name evidence="12" type="ORF">PGAL8A_00153100</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526643.1">
        <property type="nucleotide sequence ID" value="XM_028675075.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730055"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00153100"/>
    <dbReference type="OMA" id="VCKPEEH"/>
    <dbReference type="OrthoDB" id="448448at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17919">
        <property type="entry name" value="DEXHc_Snf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15489">
        <property type="entry name" value="PHD_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000048">
        <property type="entry name" value="SNF2 helicase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000399">
        <property type="entry name" value="SNF2 helicase, putative (ISWI)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10799">
        <property type="entry name" value="SNF2/RAD54 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="12" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="8">
        <location>
            <begin position="52"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="72"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="8">
        <location>
            <begin position="144"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="351"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="1166"/>
            <end position="1313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="535"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="854"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1651"/>
            <end position="1686"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1811"/>
            <end position="1842"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1931"/>
            <end position="2000"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2017"/>
            <end position="2045"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2160"/>
            <end position="2182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2545"/>
            <end position="2572"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1121"/>
            <end position="1148"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="2076"/>
            <end position="2106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="535"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="938"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="960"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1651"/>
            <end position="1681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1813"/>
            <end position="1842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1931"/>
            <end position="1951"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1953"/>
            <end position="1966"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1967"/>
            <end position="1977"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1985"/>
            <end position="2000"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="2035"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="2160"/>
            <end position="2172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="2549"/>
            <end position="2560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG93822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2604" mass="306200" checksum="5F805ABC3265D63A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNW8</accession>
    <name>A0A1J1GNW8_PLAGA</name>
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        <submittedName>
            <fullName evidence="7">E3 ubiquitin-protein ligase, putative</fullName>
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        </submittedName>
    </protein>
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        <name evidence="7" type="ORF">PGAL8A_00380500</name>
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        <name type="scientific">Plasmodium gallinaceum</name>
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            <taxon>Aconoidasida</taxon>
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            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
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                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0008270">
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        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
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        <property type="project" value="TreeGrafter"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR15710:SF243">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE PRAJA-2 ISOFORM X1"/>
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    </dbReference>
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    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
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            <end position="830"/>
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    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
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    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="912"/>
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        <location>
            <begin position="60"/>
            <end position="70"/>
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        <location>
            <begin position="71"/>
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        </location>
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    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="137"/>
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    </feature>
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        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="352"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="393"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="484"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="543"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="594"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="678"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="709"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="728"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="759"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="772"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="804"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="848"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="867"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="912"/>
            <end position="927"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG94101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="952" mass="111450" checksum="12AE3EDC148CFBBA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP82</accession>
    <name>A0A1J1GP82_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00392500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
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            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
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            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
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    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527042.1">
        <property type="nucleotide sequence ID" value="XM_028670273.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP82"/>
    <dbReference type="GeneID" id="39732455"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00392500"/>
    <dbReference type="OrthoDB" id="372598at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="760" mass="89881" checksum="47594C135CA714C3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP99</accession>
    <name>A0A1J1GP99_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00394100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
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    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527058.1">
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    <dbReference type="GeneID" id="39732471"/>
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    <dbReference type="OMA" id="NDMATEI"/>
    <dbReference type="OrthoDB" id="372418at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="386"/>
            <end position="754"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="767" mass="92393" checksum="A75AAB7CF1E400DF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPI7</accession>
    <name>A0A1J1GPI7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fam-j protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00180400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Haemosporida</taxon>
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            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527236.1">
        <property type="nucleotide sequence ID" value="XM_028670489.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPI7"/>
    <dbReference type="GeneID" id="39730331"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00180400"/>
    <dbReference type="OMA" id="ANDGEIM"/>
    <dbReference type="OrthoDB" id="10588517at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="687" mass="80231" checksum="9C2F031C4FEC1386" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPK0</accession>
    <name>A0A1J1GPK0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00091900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526037.1">
        <property type="nucleotide sequence ID" value="XM_028671766.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPK0"/>
    <dbReference type="GeneID" id="39729443"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00091900"/>
    <dbReference type="OrthoDB" id="368909at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="110" mass="13068" checksum="10855D24C38D869E" modified="2017-02-15" version="1">MDSLLNEQDKNNLLKGIGNKKIARSLLEIIMNKCDNAYFKITIEDKREFFGSLKYVDKYFLFLTDCEEHYIGNQIYVRKCGDILIPLKIIKLIEIKKSYFDNCYEELKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPM0</accession>
    <name>A0A1J1GPM0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00407700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527194.1">
        <property type="nucleotide sequence ID" value="XM_028670442.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPM0"/>
    <dbReference type="GeneID" id="39732607"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00407700"/>
    <dbReference type="OMA" id="MFIYMLL"/>
    <dbReference type="OrthoDB" id="392749at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="335"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="362"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="504"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="547"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="583"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="623"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="719"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="748"/>
            <end position="770"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="825" mass="99028" checksum="78D12989D94D5AA5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPS1</accession>
    <name>A0A1J1GPS1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00181300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527242.1">
        <property type="nucleotide sequence ID" value="XM_028670495.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPS1"/>
    <dbReference type="GeneID" id="39730340"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00181300"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="237" mass="28546" checksum="F06B41E0CB8A9CC1" modified="2017-02-15" version="1" fragment="single">LTKTFPIYFVLNLYKKIICYNKIFMLVDLKNPNHKIIKSKYKDLFIKEHSCHHIKTRYISRPSCMYAICEKENEDYVLCSDANYSGKLIFLYSANQKYKKFMYLPERCLTRDSNLECVSYFCETYAKDKFFPCEHKEISVIKDIMPYTRRSEVMPVKQQIVHHEDNLSASALFAMTLMPFLILFFFFWCYIYKNFKKRRRSKLFIKYLKKELLESNPERGNFEGKNGCTQRLEKVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPU0</accession>
    <name>A0A1J1GPU0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00401400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527131.1">
        <property type="nucleotide sequence ID" value="XM_028670372.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPU0"/>
    <dbReference type="GeneID" id="39732544"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00401400"/>
    <dbReference type="OMA" id="LYNSEYD"/>
    <dbReference type="OrthoDB" id="378770at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="365"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="408"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="431"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="464"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="529" mass="62910" checksum="5F0800CB20576429" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ55</accession>
    <name>A0A1J1GQ55_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein kinase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00196600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527386.1">
        <property type="nucleotide sequence ID" value="XM_028670656.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ55"/>
    <dbReference type="GeneID" id="39730493"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00196600"/>
    <dbReference type="OMA" id="LLKCIYQ"/>
    <dbReference type="OrthoDB" id="68483at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF77">
        <property type="entry name" value="SERINE THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="126"/>
            <end position="700"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="704" mass="86045" checksum="41E4CE16F32B4DA4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQL7</accession>
    <name>A0A1J1GQL7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Protein phosphatase 2b regulatory subunit, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CNB</name>
        <name evidence="5" type="ORF">PGAL8A_00210900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527527.1">
        <property type="nucleotide sequence ID" value="XM_028670812.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQL7"/>
    <dbReference type="GeneID" id="39730636"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00210900"/>
    <dbReference type="OMA" id="DTNFDRD"/>
    <dbReference type="OrthoDB" id="191686at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000229">
        <property type="entry name" value="Calcineurin B subunit isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45942">
        <property type="entry name" value="PROTEIN PHOSPATASE 3 REGULATORY SUBUNIT B ALPHA ISOFORM TYPE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="57"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="94"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="135"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="177" mass="20085" checksum="384D6614E34E67DC" modified="2017-02-15" version="1">MGNTQGMLSEKEQKDLLQASNFSETDIKKMYKRFIELDTNKNGELDPNELFDVPEICDNPLVKRVISIFDSNSDGKVSFVEFLVGITKLASSTDDFQKKKFAFDVYDINKDGMISNGELFTVMKMMVGNNLSDIQLQQLVDRTIIQADKDGDGMISFEEFKDMISHMDVGNKLKLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQS9</accession>
    <name>A0A1J1GQS9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Biotin carboxylase subunit of acetyl CoA carboxylase, putative</fullName>
            <ecNumber evidence="18">6.3.4.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">ACC1</name>
        <name evidence="18" type="ORF">PGAL8A_00229000</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N(6)-biotinyl-L-lysyl-[protein] + hydrogencarbonate + ATP = N(6)-carboxybiotinyl-L-lysyl-[protein] + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13501"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.14"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>hydrogencarbonate + acetyl-CoA + ATP = malonyl-CoA + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11308"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.4.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.14" evidence="18"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527708.1">
        <property type="nucleotide sequence ID" value="XM_028671013.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730817"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00229000"/>
    <dbReference type="OMA" id="TEHCKVA"/>
    <dbReference type="OrthoDB" id="196847at2759"/>
    <dbReference type="UniPathway" id="UPA00655">
        <property type="reaction ID" value="UER00711"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004075">
        <property type="term" value="F:biotin carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001295">
        <property type="term" value="P:malonyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06850">
        <property type="entry name" value="biotinyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.20:FF:000003">
        <property type="entry name" value="acetyl-CoA carboxylase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000072">
        <property type="entry name" value="Biotin carboxylase subunit of acetyl CoA carboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.460.10">
        <property type="entry name" value="Biotin dependent carboxylase carboxyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1770.10">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049076">
        <property type="entry name" value="ACCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011762">
        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45728:SF3">
        <property type="entry name" value="ACETYL-COA CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45728">
        <property type="entry name" value="ACETYL-COA CARBOXYLASE, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="Rudiment single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50980">
        <property type="entry name" value="COA_CT_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0092">Biotin</keyword>
    <keyword evidence="3 18" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013040407" evidence="12">
        <location>
            <begin position="22"/>
            <end position="2896"/>
        </location>
    </feature>
    <feature type="domain" description="Biotin carboxylation" evidence="15">
        <location>
            <begin position="382"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="14">
        <location>
            <begin position="533"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="13">
        <location>
            <begin position="1068"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase N-terminal" evidence="16">
        <location>
            <begin position="2080"/>
            <end position="2424"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="17">
        <location>
            <begin position="2516"/>
            <end position="2819"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1413"/>
            <end position="1504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="2468"/>
            <end position="2487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1423"/>
            <end position="1489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1490"/>
            <end position="1504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="2477"/>
            <end position="2487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="CRG94893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2896" mass="336780" checksum="F1210A5E43A569AD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQU9</accession>
    <name>A0A1J1GQU9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Perforin like protein 4, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PLP4</name>
        <name evidence="3" type="ORF">PGAL8A_00112400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526240.1">
        <property type="nucleotide sequence ID" value="XM_028674021.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQU9"/>
    <dbReference type="GeneID" id="39729649"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00112400"/>
    <dbReference type="OMA" id="AHGKNAH"/>
    <dbReference type="OrthoDB" id="390682at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020864">
        <property type="entry name" value="MACPF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01823">
        <property type="entry name" value="MACPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51412">
        <property type="entry name" value="MACPF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="MACPF" evidence="2">
        <location>
            <begin position="29"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="631" mass="73403" checksum="D2201E915581CE06" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQV7</accession>
    <name>A0A1J1GQV7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Multidrug resistance protein 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">MDR2</name>
        <name evidence="12" type="ORF">PGAL8A_00207100</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527489.1">
        <property type="nucleotide sequence ID" value="XM_028670770.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730598"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00207100"/>
    <dbReference type="OMA" id="FEIKRFC"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
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        <property type="entry name" value="AAA"/>
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    </dbReference>
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    </dbReference>
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            <end position="51"/>
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            <end position="89"/>
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            <begin position="101"/>
            <end position="125"/>
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            <begin position="137"/>
            <end position="160"/>
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            <end position="345"/>
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            <begin position="365"/>
            <end position="382"/>
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        <location>
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            <end position="463"/>
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        <location>
            <begin position="469"/>
            <end position="486"/>
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            <begin position="560"/>
            <end position="578"/>
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        <location>
            <begin position="330"/>
            <end position="613"/>
        </location>
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            <begin position="653"/>
            <end position="888"/>
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            <begin position="890"/>
            <end position="1373"/>
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            <begin position="892"/>
            <end position="908"/>
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            <dbReference type="PROSITE" id="PS50929"/>
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        </source>
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            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
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    <sequence length="1373" mass="159420" checksum="37DA723541B3352F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQW1</accession>
    <name>A0A1J1GQW1_PLAGA</name>
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        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
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            <taxon>Plasmodiidae</taxon>
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            <taxon>Plasmodium (Haemamoeba)</taxon>
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        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="5341" mass="635542" checksum="2605B9FA5687850A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR31</accession>
    <name>A0A1J1GR31_PLAGA</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00239600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
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            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94999.1"/>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="80"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="288" mass="34402" checksum="9F55CE1C5E03A9F1" modified="2017-02-15" version="1">MNSNYVNEIFNEAIEYKDTQKENKIKIVNDLVKNFCLLKELNLLDAIKNEEKVVPNIKLDITSYDSKNIIYANKYIVDFLQLKKQNKLKLKEEKKRKKEKYEEILNEKDVMNITNTLNENELNLSVYEKNIKNYNELNNFQTINNSLFIKYIDMPTINHNSFHIKFLQLLNLLIKNYNASLNLIKTQKNVMNYFSFYTENLLMNNKKLIEKNRKLLRNNSINMELRSKLTVNNCTEIKLPFTNQDNLSSLFQIQIDLYRKHINNLYNQIDDLKKFLNIFNVQDLSSNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRE9</accession>
    <name>A0A1J1GRE9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Centrosomal protein CEP76</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00132300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526440.1">
        <property type="nucleotide sequence ID" value="XM_028674850.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729848"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00132300"/>
    <dbReference type="OrthoDB" id="5527234at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
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        <property type="entry name" value="CEP76"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056288">
        <property type="entry name" value="CEP76_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056290">
        <property type="entry name" value="CEPT76/DRC7_peptidase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46436">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 76 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46436:SF2">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_119, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24652">
        <property type="entry name" value="CEP76_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24656">
        <property type="entry name" value="CEPT76_peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1900"/>
            <end position="1923"/>
        </location>
    </feature>
    <feature type="domain" description="CEP76/DRC7 peptidase-like" evidence="5">
        <location>
            <begin position="788"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="domain" description="Centrosomal protein of 76 kDa C-terminal" evidence="4">
        <location>
            <begin position="1850"/>
            <end position="1916"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="49"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1123"/>
            <end position="1153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1298"/>
            <end position="1319"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1412"/>
            <end position="1446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="119"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1123"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1302"/>
            <end position="1319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF24652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF24656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1941" mass="233700" checksum="4EE668FEA39BF518" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRF3</accession>
    <name>A0A1J1GRF3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00157200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526685.1">
        <property type="nucleotide sequence ID" value="XM_028675122.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRF3"/>
    <dbReference type="GeneID" id="39730097"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00157200"/>
    <dbReference type="OMA" id="KYYYKYH"/>
    <dbReference type="OrthoDB" id="382948at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="514" mass="63381" checksum="DE025359EF229757" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRF5</accession>
    <name>A0A1J1GRF5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00244400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527858.1">
        <property type="nucleotide sequence ID" value="XM_028671180.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRF5"/>
    <dbReference type="GeneID" id="39730972"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00244400"/>
    <dbReference type="OMA" id="FMIDIHD"/>
    <dbReference type="OrthoDB" id="361911at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="568"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="796"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="670"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="586"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="796"/>
            <end position="820"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="974" mass="112038" checksum="7EF6C32372FE73E3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRJ2</accession>
    <name>A0A1J1GRJ2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00253400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527942.1">
        <property type="nucleotide sequence ID" value="XM_028671273.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRJ2"/>
    <dbReference type="GeneID" id="39731062"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00253400"/>
    <dbReference type="OMA" id="IMCANIQ"/>
    <dbReference type="OrthoDB" id="381520at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45641:SF19">
        <property type="entry name" value="NEPHROCYSTIN-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45641">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13374">
        <property type="entry name" value="TPR_10"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="160"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="263" mass="30755" checksum="7E0958A3D31E6DE7" modified="2017-02-15" version="1">MVILKNLINGFSKNKKFLVFRNFCEYKKIYYNGPKHTYINSGFELKNEDTEKLIDLVKESLKLKLLTHSYCSEDIGKHYLELAILEHKNLLLNDSKNHYFKSYEIFKKINGELSIMCANIQTYIGVVYKDLGDLEKSEEFLQLSLANKKLIIKDKSYLIIDTLNNLGSLYQHKKKYNESVEYFEECIRILISSPIELNKNEQIALCYYNLSFSYIGLNDLNSAITCLIRSYTIAQNTFGPDHNLTVRIKNLHERLKNETDSNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRK7</accession>
    <name>A0A1J1GRK7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CKK domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00232900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527745.1">
        <property type="nucleotide sequence ID" value="XM_028671053.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRK7"/>
    <dbReference type="GeneID" id="39730856"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00232900"/>
    <dbReference type="OMA" id="VLFYDIN"/>
    <dbReference type="OrthoDB" id="392726at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014797">
        <property type="entry name" value="CKK_CAMSAP"/>
    </dbReference>
    <dbReference type="SMART" id="SM01051">
        <property type="entry name" value="CAMSAP_CKK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51508">
        <property type="entry name" value="CKK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CKK" evidence="1">
        <location>
            <begin position="714"/>
            <end position="840"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="840" mass="101490" checksum="AC60E72BA3A3B4F2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRX4</accession>
    <name>A0A1J1GRX4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Clp1 P-loop domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00002400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Clp1 family. NOL9/GRC3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528070.1">
        <property type="nucleotide sequence ID" value="XM_028671415.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRX4"/>
    <dbReference type="GeneID" id="39728546"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00002400"/>
    <dbReference type="OMA" id="VRIPDFY"/>
    <dbReference type="OrthoDB" id="371733at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051731">
        <property type="term" value="F:polynucleotide 5'-hydroxyl-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000448">
        <property type="term" value="P:cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045116">
        <property type="entry name" value="Clp1/Grc3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032319">
        <property type="entry name" value="CLP1_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12755">
        <property type="entry name" value="CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12755:SF3">
        <property type="entry name" value="POLYNUCLEOTIDE 5'-HYDROXYL-KINASE NOL9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16575">
        <property type="entry name" value="CLP1_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Clp1 P-loop" evidence="7">
        <location>
            <begin position="446"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="333"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="341"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1222" mass="146401" checksum="EABA2BF653CF7652" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS08</accession>
    <name>A0A1J1GS08_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA2/NAM7 helicase-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00246100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527875.1">
        <property type="nucleotide sequence ID" value="XM_028671198.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS08"/>
    <dbReference type="GeneID" id="39730989"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00246100"/>
    <dbReference type="OMA" id="DSYQGCE"/>
    <dbReference type="OrthoDB" id="392140at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027351">
        <property type="entry name" value="(+)RNA_virus_helicase_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050534">
        <property type="entry name" value="Coronavir_polyprotein_1ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43788:SF8">
        <property type="entry name" value="DNA-BINDING PROTEIN SMUBP-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43788">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01443">
        <property type="entry name" value="Viral_helicase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="(+)RNA virus helicase C-terminal" evidence="5">
        <location>
            <begin position="716"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="6">
        <location>
            <begin position="853"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="domain" description="DNA2/NAM7 helicase-like C-terminal" evidence="6">
        <location>
            <begin position="1173"/>
            <end position="1234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1269" mass="152433" checksum="D827D0CAA5165D39" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS23</accession>
    <name>A0A1J1GS23_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC transporter, (Heavy metal transporter family), putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ABCB6</name>
        <name evidence="11" type="ORF">PGAL8A_00263200</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528039.1">
        <property type="nucleotide sequence ID" value="XM_028671381.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS23"/>
    <dbReference type="GeneID" id="39731161"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00263200"/>
    <dbReference type="OMA" id="IITHTME"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18582">
        <property type="entry name" value="ABC_6TM_ATM1_ABCB7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001765">
        <property type="entry name" value="ABC transporter B family member 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221:SF503">
        <property type="entry name" value="MITOCHONDRIAL POTASSIUM CHANNEL ATP-BINDING SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="340"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="463"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="489"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="583"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="606"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="341"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="726"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="202"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="202"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="225"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG95227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="984" mass="116252" checksum="1640F2CBF33C5A05" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS59</accession>
    <name>A0A1J1GS59_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Inner membrane complex protein 1a, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00003300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528079.1">
        <property type="nucleotide sequence ID" value="XM_028671426.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS59"/>
    <dbReference type="GeneID" id="39728555"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00003300"/>
    <dbReference type="OMA" id="IPKIKWI"/>
    <dbReference type="OrthoDB" id="341024at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022086">
        <property type="entry name" value="IMCp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12314">
        <property type="entry name" value="IMCp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="522"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="538"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="558"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="568"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="594"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="618"/>
            <end position="628"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="810" mass="95186" checksum="F0621C644FEEED79" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSA5</accession>
    <name>A0A1J1GSA5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00164000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526752.1">
        <property type="nucleotide sequence ID" value="XM_028675196.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSA5"/>
    <dbReference type="GeneID" id="39730165"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00164000"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="18" mass="2203" checksum="53ED3CD7E98BC9A5" modified="2017-02-15" version="1" fragment="single">VHQNFMKTNLLENHEDSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSG2</accession>
    <name>A0A1J1GSG2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00001100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528057.1">
        <property type="nucleotide sequence ID" value="XM_028671401.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSG2"/>
    <dbReference type="GeneID" id="39728533"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00001100"/>
    <dbReference type="OMA" id="ASIYWER"/>
    <dbReference type="OrthoDB" id="10544789at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012588408" evidence="2">
        <location>
            <begin position="24"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="254"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="283" mass="32531" checksum="333E2495FEBEF28E" modified="2017-02-15" version="1">MRKNICWIFFVIFPFILFGTVLSNQEDVPTLPKEPINGNGELTEASEGRFHLRSTPDNEVLVARVKGYKSALIVQGRKLNNIKKSLDEIQTYVTNKLASIYWERTSPTQLTREEYMKEFEKFNEFYNEKMHTFDNLRNNNVVEHSKFIKYHKDLSRRINNLKVLSTEVLTEYNEVMKISKQNIELIYLNQSLCNIIQDYLNYLGKKRVDTLNATVEPLQPLSTDSSYETNSTENPPEVVEEVNISNGSNGLTKVMVIIGVLGGLCVCIGAGYFIYTKKLMNTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSS2</accession>
    <name>A0A1J1GSS2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00380300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526920.1">
        <property type="nucleotide sequence ID" value="XM_028670138.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSS2"/>
    <dbReference type="GeneID" id="39732333"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00380300"/>
    <dbReference type="OrthoDB" id="375766at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1197" mass="143692" checksum="7718E2E3B595D02C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSU5</accession>
    <name>A0A1J1GSU5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosducin-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PhLP1</name>
        <name evidence="2" type="ORF">PGAL8A_00382700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526944.1">
        <property type="nucleotide sequence ID" value="XM_028670164.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSU5"/>
    <dbReference type="GeneID" id="39732357"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00382700"/>
    <dbReference type="OMA" id="QENELMA"/>
    <dbReference type="OrthoDB" id="10257948at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02989">
        <property type="entry name" value="Phd_like_TxnDC9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21148">
        <property type="entry name" value="THIOREDOXIN DOMAIN-CONTAINING PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="78"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="193" mass="23086" checksum="91B575BBDDDED3C3" modified="2017-02-15" version="1">MNNKITKNIENQILEALKDKEDELDLEIRRYEALQKKIYDENDEELESIKNKRLQELKSKYKEKLTLLRKGHGSYKEVLSEKEFFQICKNSKKVCCHFYRNTTWRCEYLDSKLISLSKKFLNINFIKINVEKSPFLCERLKIWCIPTLMLIRDGKTEHSIIGFEELGGDNFSEKTLINVLIKWKLIDKKEIED</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSU7</accession>
    <name>A0A1J1GSU7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tetratricopeptide repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00275100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528362.1">
        <property type="nucleotide sequence ID" value="XM_028671739.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSU7"/>
    <dbReference type="GeneID" id="39731283"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00275100"/>
    <dbReference type="OMA" id="RCLNHNS"/>
    <dbReference type="OrthoDB" id="10262026at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1218" mass="148473" checksum="441E4B030A59B2B9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSW0</accession>
    <name>A0A1J1GSW0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">40S ribosomal protein S30</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00409900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the eukaryotic ribosomal protein eS30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527213.1">
        <property type="nucleotide sequence ID" value="XM_028670463.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSW0"/>
    <dbReference type="GeneID" id="39732629"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00409900"/>
    <dbReference type="OMA" id="KRRILVW"/>
    <dbReference type="OrthoDB" id="3446at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006846">
        <property type="entry name" value="Ribosomal_eS30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12650">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S30/UBIQUITIN-LIKE PROTEIN FUBI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12650:SF15">
        <property type="entry name" value="RIBOSOMAL PROTEIN S30, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04758">
        <property type="entry name" value="Ribosomal_S30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="29"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU364011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="58" mass="6543" checksum="9AD7B8EC53226E65" modified="2017-02-15" version="1">MGKVHGSLARAGKVKNQTPKVPKQDKRKPLTGRAKKRQLYNRRFSDSIGRKKGPNSQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTK1</accession>
    <name>A0A1J1GTK1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00408300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527200.1">
        <property type="nucleotide sequence ID" value="XM_028670449.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732613"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00408300"/>
    <dbReference type="OMA" id="YNKKCSQ"/>
    <dbReference type="OrthoDB" id="28145at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="173"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="865"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="950"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1293"/>
            <end position="1329"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="521"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="865"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1294"/>
            <end position="1303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1311"/>
            <end position="1329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1455" mass="175367" checksum="6A7E7129AF668C37" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTS0</accession>
    <name>A0A1J1GTS0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DEAD/DEAH box helicase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00309400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528690.1">
        <property type="nucleotide sequence ID" value="XM_028672104.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTS0"/>
    <dbReference type="GeneID" id="39731627"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00309400"/>
    <dbReference type="OrthoDB" id="348652at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10799">
        <property type="entry name" value="SNF2/RAD54 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SNF2 N-terminal" evidence="2">
        <location>
            <begin position="136"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="188" mass="22421" checksum="D3DB3700CC819709" modified="2017-02-15" version="1">MENVEEKNKKMLNSKKDIYEIDVSSNNKSLNENLYEHKDNSVKKFYPNCIQLNENYKKCENEIYNEAEMEKVDEKKDKQKLDENVFHNYTTLNYKNEEKEKISSERNNKDDKLENKKKNNETKETLEELLGELKSYQLEEFQFLINLYNNRLNGILAYEMGLGKIFQTIILLANLKESNLPILLIFKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU16</accession>
    <name>A0A1J1GU16_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Metabolite/drug transporter, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00299700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528593.1">
        <property type="nucleotide sequence ID" value="XM_028671996.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU16"/>
    <dbReference type="GeneID" id="39731530"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00299700"/>
    <dbReference type="OMA" id="FIMGINN"/>
    <dbReference type="OrthoDB" id="440755at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044770">
        <property type="entry name" value="MFS_spinster-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23505:SF52">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23505">
        <property type="entry name" value="SPINSTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="281"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="553"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="589"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="623"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="649"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="690"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="742"/>
            <end position="761"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="775" mass="91787" checksum="CAD268544B23B9AE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU94</accession>
    <name>A0A1J1GU94_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">FACT complex subunit SSRP1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00200600</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the SSRP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527424.1">
        <property type="nucleotide sequence ID" value="XM_028670697.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU94"/>
    <dbReference type="GeneID" id="39730532"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00200600"/>
    <dbReference type="OMA" id="KNEHGIT"/>
    <dbReference type="OrthoDB" id="498543at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035101">
        <property type="term" value="C:FACT complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13230">
        <property type="entry name" value="PH1_SSRP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Fact complex subunit ssrp1"/>
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    </dbReference>
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        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="2"/>
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        <property type="entry name" value="Structure-specific recognition protein (SSRP1)"/>
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        <property type="entry name" value="PH-like_dom_sf"/>
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        <property type="entry name" value="RTT106/SPT16-like_middle_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050454">
        <property type="entry name" value="RTT106/SSRP1_HistChap/FACT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048993">
        <property type="entry name" value="SSRP1-like_PH1"/>
    </dbReference>
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        <property type="entry name" value="SSRP1/POB3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035417">
        <property type="entry name" value="SSRP1/POB3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024954">
        <property type="entry name" value="SSRP1_DD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038167">
        <property type="entry name" value="SSRP1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45849">
        <property type="entry name" value="FACT COMPLEX SUBUNIT SSRP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45849:SF1">
        <property type="entry name" value="FACT COMPLEX SUBUNIT SSRP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21103">
        <property type="entry name" value="PH1_SSRP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="POB3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08512">
        <property type="entry name" value="Rttp106-like_middle"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSrecog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00887">
        <property type="entry name" value="SSRCOGNITION"/>
    </dbReference>
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        <property type="entry name" value="Rtt106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4 9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone chaperone RTT106/FACT complex subunit SPT16-like middle" evidence="11">
        <location>
            <begin position="349"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="441"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="456"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG94609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="502" mass="59054" checksum="94407153981EF34F" modified="2017-02-15" version="1">MGDNNGTNSNNNSVISIGNIRGFGGGDYGSFRMSNEFLGWKNKKTNNVYQYKFSDISEGEWIKTSYNNNRLHLKLIESKDNLIVYFDGFPDRNINEITQHFQKYFNIRLSNRKITTKGWNWGEFKFENSNLLFDIDKKYAFNIPTNNINQLNVQIKTDIAMELKNEENQTNEDSLAEIRFYYPHENDENQTFQNLKNDLLEKVNIGDSKSESIASLTNIPLLVPRGRYEIEMYIRTFKLHGKSYDFTIQYTNINKMILVPKSNSNQYVLIFSLNNKMKQGQTEYPFILIQLNNDDDMDININANEEIIKKYKLEKTISGKPYDVVTRLFTSLVKKSVIIPGDFRTAKNQYGITCSYRAASGQLYPLNKYFLFIIKPVILISFEDIVTLSFQRTGNINQHRFFSLIIKHKRGISYEYTNIDKNEYVPLLNFLKSKNLNIQDDANNTENKQDFRDELSESDEEEYVEDEDEEDYVAEEEEEEEEEEEEEEEEEEEEEEEDDENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUA7</accession>
    <name>A0A1J1GUA7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Serine/threonine protein kinase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SRPK2</name>
        <name evidence="7" type="ORF">PGAL8A_00202200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527440.1">
        <property type="nucleotide sequence ID" value="XM_028670715.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUA7"/>
    <dbReference type="GeneID" id="39730548"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00202200"/>
    <dbReference type="OMA" id="IMINMKR"/>
    <dbReference type="OrthoDB" id="9332038at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000812">
        <property type="entry name" value="CMGC/DYRK protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050494">
        <property type="entry name" value="Ser_Thr_dual-spec_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058:SF124">
        <property type="entry name" value="PROTEIN KINASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="703"/>
            <end position="1252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG94625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1261" mass="149510" checksum="2F51CB718350EEEB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUC2</accession>
    <name>A0A1J1GUC2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Eukaryotic initiation factor 2alpha kinase 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00203700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527456.1">
        <property type="nucleotide sequence ID" value="XM_028670733.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730564"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00203700"/>
    <dbReference type="OMA" id="HELRYAD"/>
    <dbReference type="OrthoDB" id="341578at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033554">
        <property type="term" value="P:cellular response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13996">
        <property type="entry name" value="STKc_EIF2AK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050339">
        <property type="entry name" value="CC_SR_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042:SF178">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="5" id="KW-0652">Protein synthesis inhibitor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="406"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="255"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="344"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="435"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG94641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1369" mass="161237" checksum="45BF7F0DCFF12017" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUD0</accession>
    <name>A0A1J1GUD0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Small ribosomal subunit protein mS29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00204500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mS29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527464.1">
        <property type="nucleotide sequence ID" value="XM_028670741.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUD0"/>
    <dbReference type="GeneID" id="39730572"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00204500"/>
    <dbReference type="OMA" id="MYINVKN"/>
    <dbReference type="OrthoDB" id="274828at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001772">
        <property type="entry name" value="KA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019368">
        <property type="entry name" value="Ribosomal_mS29"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12810">
        <property type="entry name" value="MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12810:SF0">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10236">
        <property type="entry name" value="DAP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50032">
        <property type="entry name" value="KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="KA1" evidence="8">
        <location>
            <begin position="132"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="585" mass="70322" checksum="EE9494AAAA444AD9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUD3</accession>
    <name>A0A1J1GUD3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mechanosensitive ion channel protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00335200</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528942.1">
        <property type="nucleotide sequence ID" value="XM_028672384.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731882"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00335200"/>
    <dbReference type="OMA" id="MYYQEKN"/>
    <dbReference type="OrthoDB" id="544685at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006820">
        <property type="term" value="P:monoatomic anion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016688">
        <property type="entry name" value="MscS-like_plants/fungi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_beta-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31618:SF1">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31618">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="124"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="225"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1081"/>
            <end position="1100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1106"/>
            <end position="1136"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="8">
        <location>
            <begin position="1025"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="507"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="561"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="507"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="522"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="561"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="573"/>
            <end position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG96137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1657" mass="194424" checksum="44F3138B38FBA218" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUD4</accession>
    <name>A0A1J1GUD4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CPW-WPC family protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00330800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528898.1">
        <property type="nucleotide sequence ID" value="XM_028672336.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUD4"/>
    <dbReference type="GeneID" id="39731838"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00330800"/>
    <dbReference type="OMA" id="HIWELPK"/>
    <dbReference type="OrthoDB" id="382272at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006387">
        <property type="entry name" value="CPW_WPC_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01492">
        <property type="entry name" value="CPW_WPC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09717">
        <property type="entry name" value="CPW_WPC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01099">
        <property type="entry name" value="CPW_WPC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012430212" evidence="1">
        <location>
            <begin position="19"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="domain" description="CPW-WPC" evidence="2">
        <location>
            <begin position="231"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="CPW-WPC" evidence="2">
        <location>
            <begin position="293"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="CPW-WPC" evidence="2">
        <location>
            <begin position="356"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="CPW-WPC" evidence="2">
        <location>
            <begin position="420"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="CPW-WPC" evidence="2">
        <location>
            <begin position="486"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="581" mass="67086" checksum="6983285F8408B52D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUG5</accession>
    <name>A0A1J1GUG5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Crossover junction endonuclease MUS81</fullName>
            <ecNumber evidence="2">3.1.22.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MUS81</name>
        <name evidence="6" type="ORF">PGAL8A_00208600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Interacts with EME1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the XPF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.22.-" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527504.1">
        <property type="nucleotide sequence ID" value="XM_028670786.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUG5"/>
    <dbReference type="GeneID" id="39730613"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00208600"/>
    <dbReference type="OMA" id="DIIWLCR"/>
    <dbReference type="OrthoDB" id="5963188at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048476">
        <property type="term" value="C:Holliday junction resolvase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048257">
        <property type="term" value="F:3'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction DNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031573">
        <property type="term" value="P:mitotic intra-S DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20074">
        <property type="entry name" value="XPF_nuclease_Mus81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.110">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027421">
        <property type="entry name" value="DNA_pol_lamdba_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006166">
        <property type="entry name" value="ERCC4_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033309">
        <property type="entry name" value="Mus81"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047416">
        <property type="entry name" value="XPF_nuclease_Mus81"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13451">
        <property type="entry name" value="CLASS II CROSSOVER JUNCTION ENDONUCLEASE MUS81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13451:SF0">
        <property type="entry name" value="CROSSOVER JUNCTION ENDONUCLEASE MUS81"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02732">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00891">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47802">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="Restriction endonuclease-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2 6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERCC4" evidence="5">
        <location>
            <begin position="926"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="459"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="877"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="979"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="539"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="877"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="986"/>
            <end position="995"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU369042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG94689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1260" mass="149378" checksum="0B2D3A0317F6D86D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUJ0</accession>
    <name>A0A1J1GUJ0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00237300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527789.1">
        <property type="nucleotide sequence ID" value="XM_028671104.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730901"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00237300"/>
    <dbReference type="OMA" id="EMEYSAR"/>
    <dbReference type="OrthoDB" id="387698at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3110">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32083">
        <property type="entry name" value="CILIA AND FLAGELLA-ASSOCIATED PROTEIN 58-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32083:SF48">
        <property type="entry name" value="TRANS-GOLGI NETWORK-LOCALIZED SYP41-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1127"/>
            <end position="1163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1210"/>
            <end position="1250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1817"/>
            <end position="1853"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1865"/>
            <end position="1921"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1002"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="2180"/>
            <end position="2261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="17"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1148"/>
            <end position="1158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1822"/>
            <end position="1853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1865"/>
            <end position="1892"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1900"/>
            <end position="1921"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3308" mass="391683" checksum="77376352FD764223" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV59</accession>
    <name>A0A1J1GV59_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00339000</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
            <location evidence="1">Centromere</location>
            <location evidence="1">Kinetochore</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528977.1">
        <property type="nucleotide sequence ID" value="XM_028672424.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731920"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00339000"/>
    <dbReference type="OMA" id="MNKSNGM"/>
    <dbReference type="OrthoDB" id="248495at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051754">
        <property type="term" value="P:meiotic sister chromatid cohesion, centromeric"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015661">
        <property type="entry name" value="Bub1/Mad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14030:SF4">
        <property type="entry name" value="BUB1 KINASE, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14030">
        <property type="entry name" value="MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0137">Centromere</keyword>
    <keyword evidence="2" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="1478"/>
            <end position="1839"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="803"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="2077"/>
            <end position="2113"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1047"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1164"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="2080"/>
            <end position="2109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG96172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2278" mass="274285" checksum="6D2C77E02A134339" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVG6</accession>
    <name>A0A1J1GVG6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase, putative</fullName>
            <ecNumber evidence="2">2.1.1.43</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00370200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.43" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529282.1">
        <property type="nucleotide sequence ID" value="XM_028672762.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVG6"/>
    <dbReference type="GeneID" id="39732232"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00370200"/>
    <dbReference type="OMA" id="IQNKHYE"/>
    <dbReference type="OrthoDB" id="46564at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF165">
        <property type="entry name" value="FAM86 N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="61"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="585" mass="68750" checksum="05EFD1228B66F6ED" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVN4</accession>
    <name>A0A1J1GVN4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RanBPM and CLTH-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00247400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527888.1">
        <property type="nucleotide sequence ID" value="XM_028671214.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVN4"/>
    <dbReference type="GeneID" id="39731002"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00247400"/>
    <dbReference type="OMA" id="KMILWAQ"/>
    <dbReference type="OrthoDB" id="2415936at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013144">
        <property type="entry name" value="CRA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024964">
        <property type="entry name" value="CTLH/CRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006595">
        <property type="entry name" value="CTLH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050618">
        <property type="entry name" value="Ubq-SigPath_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12864">
        <property type="entry name" value="RAN BINDING PROTEIN 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10607">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00757">
        <property type="entry name" value="CRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00668">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50897">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CTLH" evidence="2">
        <location>
            <begin position="67"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="281" mass="33459" checksum="7CF48C1510E8C41F" modified="2017-02-15" version="1">MNENSIDENCHVCLNPKNWLKEFEYTKIHENDLNEVLMNYFCVHRMYDVANEFKKEANVKPDMPIDTVKTRYLIQSEIMNNKIEKAIEHINNLDQGILKKHKDIIFFLKKQQLLKLILNNNINEAIVYSQQELAPYVKEKPSLINEIDDVMMLMAYQDLNSEEAKKLIQKIEKKKNTLKRIDDIILSYYNVDKSTLEYIVKNVFFTQNILSSKYPCSIPKLKNLKTGYIEYYEKYKKKKKKNSEKKNRNKNKGKIDYFNDKNFESISKGFDATNDEEYRSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVT8</accession>
    <name>A0A1J1GVT8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Serine repeat antigen, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00017100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528213.1">
        <property type="nucleotide sequence ID" value="XM_028671574.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVT8"/>
    <dbReference type="GeneID" id="39728693"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00017100"/>
    <dbReference type="OMA" id="VMMNCEY"/>
    <dbReference type="OrthoDB" id="405971at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02619">
        <property type="entry name" value="Peptidase_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000169">
        <property type="entry name" value="Pept_cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013128">
        <property type="entry name" value="Peptidase_C1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000668">
        <property type="entry name" value="Peptidase_C1A_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12411">
        <property type="entry name" value="CYSTEINE PROTEASE FAMILY C1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00112">
        <property type="entry name" value="Peptidase_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00705">
        <property type="entry name" value="PAPAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00645">
        <property type="entry name" value="Pept_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00139">
        <property type="entry name" value="THIOL_PROTEASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0865">Zymogen</keyword>
    <feature type="domain" description="Peptidase C1A papain C-terminal" evidence="7">
        <location>
            <begin position="209"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="539"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="548"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="669" mass="77709" checksum="6C48C40940DB7E5E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW51</accession>
    <name>A0A1J1GW51_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00427400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529498.1">
        <property type="nucleotide sequence ID" value="XM_028673002.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732806"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00427400"/>
    <dbReference type="OMA" id="THMNTNK"/>
    <dbReference type="OrthoDB" id="387454at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="487"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="574"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="949"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="617"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1177"/>
            <end position="1211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="495"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="592"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="949"/>
            <end position="982"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1552" mass="185587" checksum="AF40CF3775D12DD5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWF1</accession>
    <name>A0A1J1GWF1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Trafficking protein particle complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00010000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Part of the multisubunit transport protein particle (TRAPP) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Golgi apparatus</location>
            <location evidence="7">cis-Golgi network</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAPP small subunits family. TRAPPC4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528144.1">
        <property type="nucleotide sequence ID" value="XM_028671497.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWF1"/>
    <dbReference type="GeneID" id="39728622"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00010000"/>
    <dbReference type="OMA" id="MPIRTEG"/>
    <dbReference type="OrthoDB" id="246406at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030008">
        <property type="term" value="C:TRAPP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd14856">
        <property type="entry name" value="TRAPPC4_synbindin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007233">
        <property type="entry name" value="TRAPPC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23249">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23249:SF15">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04099">
        <property type="entry name" value="Sybindin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01399">
        <property type="entry name" value="Sybindin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4 7" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="5 7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="145" mass="16977" checksum="80B50C9062E58DE3" modified="2017-02-15" version="1">MYSLYVNNQHGTLVYQKHFSEEIKLNSNEEIRLASMLHGISTISEKINVHSLNEKKNNIFKLLEKKGIETIEGDGFKIQCYDTLTGIKIFIVHKDDLNIEMNSYLKKVYELYSDIILKNPFYDIDMPIRSAVFNEHIEKLFSNLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWL3</accession>
    <name>A0A1J1GWL3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Vacuolar transporter chaperone, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00451900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529742.1">
        <property type="nucleotide sequence ID" value="XM_028673272.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWL3"/>
    <dbReference type="GeneID" id="39733052"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00451900"/>
    <dbReference type="OMA" id="NEHYNEH"/>
    <dbReference type="OrthoDB" id="2243669at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006799">
        <property type="term" value="P:polyphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14447">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.100.30">
        <property type="entry name" value="VTC, catalytic tunnel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003807">
        <property type="entry name" value="DUF202"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051572">
        <property type="entry name" value="VTC_Complex_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042267">
        <property type="entry name" value="VTC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46140:SF1">
        <property type="entry name" value="VACUOLAR TRANSPORTER CHAPERONE COMPLEX SUBUNIT 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02656">
        <property type="entry name" value="DUF202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="886"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="929"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="8">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="522"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="526"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG96939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="955" mass="114076" checksum="3E7E724F21C9374D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWQ8</accession>
    <name>A0A1J1GWQ8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PIH1 domain-containing protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PIH1</name>
        <name evidence="3" type="ORF">PGAL8A_00456700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PIH1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529790.1">
        <property type="nucleotide sequence ID" value="XM_028673327.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWQ8"/>
    <dbReference type="GeneID" id="39733100"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00456700"/>
    <dbReference type="OMA" id="FDFKPPF"/>
    <dbReference type="OrthoDB" id="5135119at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050734">
        <property type="entry name" value="PIH1/Kintoun_subfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012981">
        <property type="entry name" value="PIH1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22997">
        <property type="entry name" value="PIH1 DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22997:SF0">
        <property type="entry name" value="PIH1 DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08190">
        <property type="entry name" value="PIH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PIH1 N-terminal" evidence="2">
        <location>
            <begin position="29"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="414" mass="49361" checksum="2C5C856154F0C6BC" modified="2017-02-15" version="1">MNNIYEYFFQEKNKNIQFSNDKLNDLLQNKKTIKISPQKGFVIKTYEKQGGKVYFNICASNLIAEFHLKKIPDLNNEEGLRIPLSIGEEKNKEDKKGNKYKTYDIVLNTKIVIESKKNLELKKIIAELVQVAVKNKYKTETCANLFFFPEHKYKGSNPDDQYIKDDQQHKFNIIEEGHEDENKKNDKNHIRENKEIENYLTIKKPEWDMWFINKNIIEEKYKTMNEFYIPYIRKFPLKDVIDCFDYKPPFLKCKKKKEQKKNQIFKSFLNEYNIELDDEFLSYEKIINTICVIQIQLPFFLLAEHNKKNNNSTFVISQFVNLYICDEFLSVFFKKSPLFPLEYNPPYKNFNIRFPFYFESSKAKSHYLEKYHLLNIIIPVSKSCASSVIFKDVIENSKDNSSNYNDETSDSSIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX37</accession>
    <name>A0A1J1GX37_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fam-b protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00461100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529834.1">
        <property type="nucleotide sequence ID" value="XM_028673375.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX37"/>
    <dbReference type="GeneID" id="39733144"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00461100"/>
    <dbReference type="OMA" id="HNLAEQW"/>
    <dbReference type="OrthoDB" id="370995at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012837000" description="Fam-b protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="175" mass="21244" checksum="148D254D404BA54C" modified="2017-02-15" version="1">MIILKFLFFIHIFIIYVNSMNPIKRGNENFPVNNITEETDNFDSEYPSFNVHYNFEPKDWKDIELINKKNNDILNDIKNEIVKMKEDKLKINYVLNIQKQQLEELIFLINYIYSNKVKNIVEMPQYLRSGNFDSYKLNNNKIEETYNEINNNIMNKSKFIEKKNFYFNLAEQWIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX81</accession>
    <name>A0A1J1GX81_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00443700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529659.1">
        <property type="nucleotide sequence ID" value="XM_028673180.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732970"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00443700"/>
    <dbReference type="OrthoDB" id="5370059at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051625">
        <property type="entry name" value="Signaling_Regulatory_Domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22872">
        <property type="entry name" value="BTK-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00415">
        <property type="entry name" value="RCC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1361"/>
            <end position="1384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1740"/>
            <end position="1758"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1797"/>
            <end position="1820"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1841"/>
            <end position="1861"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="2348"/>
            <end position="2367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="2373"/>
            <end position="2391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="2403"/>
            <end position="2420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="2426"/>
            <end position="2446"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="3188"/>
            <end position="3215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="768"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2258"/>
            <end position="2278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2655"/>
            <end position="2680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="3091"/>
            <end position="3135"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="913"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="2258"/>
            <end position="2274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="2655"/>
            <end position="2677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="3091"/>
            <end position="3106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="3123"/>
            <end position="3134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="4141" mass="498062" checksum="891637E460C2B6D3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXI4</accession>
    <name>A0A1J1GXI4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Gfo/Idh/MocA-like oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00458600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529809.1">
        <property type="nucleotide sequence ID" value="XM_028673348.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXI4"/>
    <dbReference type="GeneID" id="39733119"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00458600"/>
    <dbReference type="OMA" id="FYWNIFN"/>
    <dbReference type="OrthoDB" id="64915at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="369" mass="43419" checksum="73119EDDD41014E9" modified="2017-02-15" version="1">MILNKPSICLICDKEAFKWIPVIINEWKIKYLFCNDEKLKNCFIDTFNLNDTETNTTNDIFEYLDCLNPENVDLLFLSLPTNEFHELLIENIIKQKKFFFVFSSNLPTLNIEKLKNFRTLLNNFNITTNIIYDVKEEFKNKNKQFYWNIFNPLLNEQVFHNLKNVLNELGYIYGVQAESTFIPYFVENEEVKNILFYRCILMISLIEFLFEKSKHALGKCYSIKNENVSINCIAGNVVFDSLNCNFIISTNSPNKIFTLKIYGENGFIIVSYNKEHNCFQLQRCLNHYEYPSLFIGDSQQSALNELKYFVEEKLYTNKYVNNYIDAMHVSLNLWKSEGANISLENENSNYTNENINNKKLVIENNCVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXK3</accession>
    <name>A0A1J1GXK3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00454800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529771.1">
        <property type="nucleotide sequence ID" value="XM_028673304.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXK3"/>
    <dbReference type="GeneID" id="39733081"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00454800"/>
    <dbReference type="OMA" id="HEDNDQN"/>
    <dbReference type="OrthoDB" id="205403at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013865">
        <property type="entry name" value="FAM32A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13282">
        <property type="entry name" value="PROTEIN FAM32A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13282:SF6">
        <property type="entry name" value="PROTEIN FAM32A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08555">
        <property type="entry name" value="FAM32A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="18"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="73"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="140" mass="16471" checksum="03CBB447041C9CAB" modified="2017-02-15" version="1">MKDSEFVGGKLKIKGLKIKTTNKKKKRKEKSSKNYSTTIENNENKYNDEECFTKDNKNEKTKNKQDIESLNKIDDEEKLKEILESNLTEAEKAYQLVLKKREKQRIENILKESYRERLQKFNDNLASLSEHFDIPKVGPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXL4</accession>
    <name>A0A1J1GXL4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Schizont egress antigen-1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SEA1</name>
        <name evidence="3" type="ORF">PGAL8A_00481000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530034.1">
        <property type="nucleotide sequence ID" value="XM_028673597.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733343"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00481000"/>
    <dbReference type="OMA" id="RHHHVDQ"/>
    <dbReference type="OrthoDB" id="387428at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="653"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1353"/>
            <end position="1381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1585"/>
            <end position="1694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1706"/>
            <end position="1760"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1804"/>
            <end position="1830"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="704"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="653"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1360"/>
            <end position="1381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1594"/>
            <end position="1617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1675"/>
            <end position="1686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1726"/>
            <end position="1745"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2098" mass="251543" checksum="44E76B29E786210C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXN9</accession>
    <name>A0A1J1GXN9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00326900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000053">
        <property type="protein sequence ID" value="CRG96053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528861.1">
        <property type="nucleotide sequence ID" value="XM_028672294.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXN9"/>
    <dbReference type="GeneID" id="39731799"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00326900"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="283" mass="34029" checksum="564516FCE8675BCB" modified="2017-02-15" version="1">MRTLTLYLKITTFLLLIWMYQCFYNCYSYKTWIDKNILETKNELKYERLLTEGDIEGEKHNYAEGCLKECPLDNEKKGSMDPDKYKNPCDPRHRINTPSLFERFNKKASEMDPNLRDHELNIEWNNISQNKLIHLSSKIYQRDIPDEGKDILILSETKDHSELKKLLDEFKNEIRDNKAESESKKEVRDNRIESESEKEMRTNKTESESEKELRDNRTELESKKEMIDIKKEFEWIKEMIDNKTECESESESECENENEMRENKKKKKKSNILKFLFCGCYNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXV6</accession>
    <name>A0A1J1GXV6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA replication origin binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">DIA2</name>
        <name evidence="2" type="ORF">PGAL8A_00467700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529899.1">
        <property type="nucleotide sequence ID" value="XM_028673448.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXV6"/>
    <dbReference type="GeneID" id="39733210"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00467700"/>
    <dbReference type="OMA" id="NINNRQY"/>
    <dbReference type="OrthoDB" id="2117972at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045464">
        <property type="entry name" value="Hrt3/FBXO9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036181">
        <property type="entry name" value="MIT_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19270">
        <property type="entry name" value="FBO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116846">
        <property type="entry name" value="MIT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box protein Hrt3/FBXO9 C-terminal" evidence="1">
        <location>
            <begin position="142"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="361" mass="43704" checksum="28D1544CFE89B9DC" modified="2017-02-15" version="1">MSEKKNQSNDKSIKYSNSNKEKAKKLFAKAINYEYDENFLKATKFYQEAVKLYPKILNIYTNENSENIDKNESTEENDNDKNSYLINILSKNFYSIIKFLDFYSMHRFHFLCKNIYSLISLENEYKRLCEINFTKHEEKIKLYENSYKRLLLEYPRIRYDGVYISCITYIRPLKDIGNIHLDPKDRDRVIYNPCFITYFRYLLFLNESNKVLILRSEVNKKEVLEALKISYNKIKKWNLLLSCDELIKDLLKFQSESENNIVKFIRIGEYKFNKDERIIEIHYSELLNEPNKYKNLIQLRLQNYLSGNNNMLKWVSFKILSKIKFNYSEDTLNINNKQYRSFFFFNLKFLSHLFITKISEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYA5</accession>
    <name>A0A1J1GYA5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 16">CDP-diacylglycerol--inositol 3-phosphatidyltransferase</fullName>
            <ecNumber evidence="5 16">2.7.8.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">PIS</name>
        <name evidence="19" type="ORF">PGAL8A_00511900</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a CDP-1,2-diacyl-sn-glycerol + myo-inositol = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11580"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:57880"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="2.7.8.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 16 17">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.11" evidence="5 16"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530347.1">
        <property type="nucleotide sequence ID" value="XM_028673945.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYA5"/>
    <dbReference type="GeneID" id="39733652"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00511900"/>
    <dbReference type="OMA" id="VTGVFFY"/>
    <dbReference type="OrthoDB" id="10251079at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003881">
        <property type="term" value="F:CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006661">
        <property type="term" value="P:phosphatidylinositol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048254">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014387">
        <property type="entry name" value="CDP_diag_ino_3_P_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15362:SF4">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--INOSITOL 3-PHOSPHATIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15362">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000848">
        <property type="entry name" value="CDP_diag_ino_3_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 16" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12 16" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13 16 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14 16" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="15 16" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 16 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR000848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="CRG97546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="209" mass="24055" checksum="0819BD1B58894A6E" modified="2017-02-15" version="1">MKKNVYLYIPNIIGYIRVILALFGFMICRQNLPIFAVFYATSQMLDGLDGWTARKYNQTSVFGQILDQITDRLSTCLLYLLISNVYDKYVLVVGLIMIADIGGHYFHSTSCAIAGNRTHKKIEKGNRLLKLYYERQSVMVMCIIAYESFLISIYILKVASEKSLIYILSYYAIKFCFPLAAFKVFTNVSQGIYGVKRLVEMDCKKNEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYE8</accession>
    <name>A0A1J1GYE8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Mitochondrial preribosomal assembly protein rimM, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00491400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530137.1">
        <property type="nucleotide sequence ID" value="XM_028673712.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYE8"/>
    <dbReference type="GeneID" id="39733447"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00491400"/>
    <dbReference type="OMA" id="NDIRFKK"/>
    <dbReference type="OrthoDB" id="364858at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.60">
        <property type="entry name" value="RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00014">
        <property type="entry name" value="Ribosome_mat_RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011961">
        <property type="entry name" value="RimM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002676">
        <property type="entry name" value="RimM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036976">
        <property type="entry name" value="RimM_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33692">
        <property type="entry name" value="RIBOSOME MATURATION FACTOR RIMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33692:SF1">
        <property type="entry name" value="RIBOSOME MATURATION FACTOR RIMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01782">
        <property type="entry name" value="RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="6">
        <location>
            <begin position="549"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="643" mass="76405" checksum="23CA0D9285351C7B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYK4</accession>
    <name>A0A1J1GYK4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">Exportin-T</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 9">Exportin(tRNA)</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8 9">tRNA exportin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00512200</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
        <text evidence="9">Shuttles between the nucleus and the cytoplasm.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the exportin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530350.1">
        <property type="nucleotide sequence ID" value="XM_028673948.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYK4"/>
    <dbReference type="GeneID" id="39733655"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00512200"/>
    <dbReference type="OrthoDB" id="26399at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016363">
        <property type="term" value="C:nuclear matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071528">
        <property type="term" value="P:tRNA re-export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013598">
        <property type="entry name" value="Exportin-1/Importin-b-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040017">
        <property type="entry name" value="XPOT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15952:SF11">
        <property type="entry name" value="EXPORTIN-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15952">
        <property type="entry name" value="EXPORTIN-T/LOS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08389">
        <property type="entry name" value="Xpo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="9" id="KW-0813">Transport</keyword>
    <keyword evidence="4 9" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Exportin-1/Importin-beta-like" evidence="10">
        <location>
            <begin position="75"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG97549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1143" mass="133270" checksum="CB7B57B61E24941E" modified="2017-02-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYV0</accession>
    <name>A0A1J1GYV0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/beta hydrolase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00370500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529285.1">
        <property type="nucleotide sequence ID" value="XM_028672765.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYV0"/>
    <dbReference type="GeneID" id="39732235"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00370500"/>
    <dbReference type="OMA" id="QFICMSL"/>
    <dbReference type="OrthoDB" id="194865at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46118">
        <property type="entry name" value="PROTEIN ABHD11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46118:SF4">
        <property type="entry name" value="PROTEIN ABHD11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="117"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="373" mass="44194" checksum="9A55B0C2808F56FA" modified="2017-02-15" version="1">MSLLIFKFIFLFYYLFFFEGKNIKAIYFKRSLQNNKRSMMRSLYLNLHKINVLKFKNKIKNYEFNTKKYVLLNCSKNFFSTFSLSDDDKEIEHKIDQMSFTIRDNTNIYKEETKNIPILLIHGCYGSKKNFRNFSKMLKSNKIIILDLRNHGDSKHTESMKYVDMETDIKNVLEKLHIKKCCLVGFSLGGKVSMYCALKNPTLFSRLIIMDILPFNYNSNKIHIKQPYNIVQMTNILHKIKKKEPKNKNEFLKYLKEELPDISNTFAQFICMSLKENDKKNQLIWKINVDTIYNELSHIMNFPLNSDNYKYFNPCSFIIGKKSDLVFSIPQFNNIINSFFPNSKQFILENSSHTVYIDEAQKCSNIINNTLCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYW0</accession>
    <name>A0A1J1GYW0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00499700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530226.1">
        <property type="nucleotide sequence ID" value="XM_028673811.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYW0"/>
    <dbReference type="GeneID" id="39733530"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00499700"/>
    <dbReference type="OrthoDB" id="392073at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005740">
        <property type="term" value="C:mitochondrial envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050754">
        <property type="entry name" value="FKBP4/5/8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46512">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46512:SF1">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="842"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="560"/>
            <end position="622"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="939" mass="112402" checksum="A7A6476AAFEDDB57" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ33</accession>
    <name>A0A1J1GZ33_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Geranylgeranyl transferase type II subunit beta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Type II protein geranyl-geranyltransferase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00528900</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein prenyltransferase subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530513.1">
        <property type="nucleotide sequence ID" value="XM_028674129.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ33"/>
    <dbReference type="GeneID" id="39733822"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00528900"/>
    <dbReference type="OMA" id="DVCYAWW"/>
    <dbReference type="OrthoDB" id="24893at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005968">
        <property type="term" value="C:Rab-protein geranylgeranyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004663">
        <property type="term" value="F:Rab geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045089">
        <property type="entry name" value="PGGT1B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001330">
        <property type="entry name" value="Prenyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774:SF11">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00432">
        <property type="entry name" value="Prenyltrans"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="451"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="Prenyltransferase alpha-alpha toroid" evidence="11">
        <location>
            <begin position="30"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="Prenyltransferase alpha-alpha toroid" evidence="11">
        <location>
            <begin position="193"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG97712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="511" mass="60423" checksum="2599CA300E5732B6" modified="2017-02-15" version="1">MELHLSLHEKYFLNTIIENLSNKSNVKKLSNKHESIFLNGIFWVLSGLLMINKNRKSLHEILKKEIIDIIYVLVMQCLQKKKIKEKYIYNLKKEKYLFSDKDIDKIINSTENDYNKIDYKNIKKYEDERINFSSLNIDFVEKNSNTNNSNMYDHQECNEINNNELKSDVSNGIYNKNSEKYKKKKNIIKFVVRGFSPCNKKYLYEPNVISTLSAIQILFLLNKISENDISTKVLLEICNFIIFLLNEEKGFFHFSLSSLRYHFDGDMRFMFCSLASLHLINLILKKRNIYINIFNNKDKCVNWIINCFNIDGGFSNYPGSESHAGTTFCAINSLNFLKDENNKSYFSYNSISKKKLIRWLCDRYENYGINGRVGKDHDVCYAWWVLSSLVALKKSLKKLFNINILIDYILKCQDENNGGFSRIEQTENNIKRQNFSYFVSENMIFRETDQFHSFFSICALSLIYYNVYYKKKKNERYLFFDNSIIPKNLEESLSNLKNVHVSFAMPIHILN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZC7</accession>
    <name>A0A1J1GZC7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MOLO1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00025700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530622.1">
        <property type="nucleotide sequence ID" value="XM_028674250.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZC7"/>
    <dbReference type="GeneID" id="39728780"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00025700"/>
    <dbReference type="OMA" id="GIGNKEC"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005892">
        <property type="term" value="C:acetylcholine-gated channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033438">
        <property type="entry name" value="MOLO1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33748:SF5">
        <property type="entry name" value="GROUND-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33748">
        <property type="entry name" value="PROTEIN CBG04600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17175">
        <property type="entry name" value="MOLO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="249"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="275" mass="32066" checksum="26F7A489C3F499E1" modified="2017-02-15" version="1">MNILFIIMYFFFFFFFLKFGLCGKSNSLDKFYFNDVKSTKNNIIPGSKVLYPLIQDLEENDDYFNIDNIYDEMSFPDPFIQPEECVLSLGISHSWLCDPSRFLNLNEQLNVEAALLKIRDTNFHKCSNNGIYYYQVSVALVPQIHIDKNNSHEKSAQIFAHNLLRKWGIGNKECHDGILFVYIKQLGKFIVVKREGVENQYINENEIRMQFMNTYFATGSLSKALIESLNFVNKKLPSKHQELTNTAKMFLLLILFYIVSVIILYITTVTYGKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H012</accession>
    <name>A0A1J1H012_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Calcyclin binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00446300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529685.1">
        <property type="nucleotide sequence ID" value="XM_028673209.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H012"/>
    <dbReference type="GeneID" id="39732996"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00446300"/>
    <dbReference type="OMA" id="KVHMTAD"/>
    <dbReference type="OrthoDB" id="1898560at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06466">
        <property type="entry name" value="p23_CS_SGT1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007699">
        <property type="entry name" value="SGS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044563">
        <property type="entry name" value="Sgt1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45862">
        <property type="entry name" value="PROTEIN SGT1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05002">
        <property type="entry name" value="SGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51048">
        <property type="entry name" value="SGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="2">
        <location>
            <begin position="32"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="SGS" evidence="1">
        <location>
            <begin position="137"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="217" mass="25846" checksum="60770D7D041F1B4B" modified="2017-02-15" version="1">MDNEYCNLDNIFSNTKLNELNKLRNIKLVVNDKIIRHDWSQTSDNIFFTIYRKNIQKNDFLYYIENDYIFLTIIINEEEIYVIENFLFSKILPSKTKINITPMKVEITFEKEIKELKWNEFIKIENSINLKKKENILNPFSGKSTEEWNKLTKSIKEDDDEGSIDSFFRKIYNEGDDDTKRAMIKSFQTSCGTVLSTNWKDVQNKNYEKEISPNGQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H033</accession>
    <name>A0A1J1H033_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transporter, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00421600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529440.1">
        <property type="nucleotide sequence ID" value="XM_028672937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H033"/>
    <dbReference type="GeneID" id="39732748"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00421600"/>
    <dbReference type="OMA" id="CFYNIYK"/>
    <dbReference type="OrthoDB" id="270584at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="282"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="414"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="123"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="225"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="409"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG96636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="508" mass="59874" checksum="29CE70027EFF87AB" modified="2017-02-15" version="1">MKNVINENIIENLNIYDHSINKTINDKVDVKKLKKIEINENNLHNYLSKNNMVNESKYNLDSYNEKKNMNKKDIIVIENNVNNEDYYNTNEKNKEKKETNYNSESSVKNKKILKDFDIFVDKKNAINSIISSAFAGIMSRTITAPLDRVKYIMQITNNLPISEIFKIIKKDGIFCGFFRGNCVNIVKIIPELSIKMYSYEFMKLNVYNYYNKTNNCVSNEENINIPFFIRFLIGSSSGVIAALFIYPLEIVKTRLIVSNKNDDNGIIKCFYNIYKNERCRNFYNGLSMHIYGVLFFSGCNMSIYDYLKYLFFSFYKDYIHSNYCLKNVYKKGNDFFSDTNNKNNNYFHIYNNNNNNNNGKNFLLKTVSNSDNIKKDSEHKWNNKNYQNKGEDIMNKISCSYCDYRIKNVNCLSFLFFGITSSFIAQIVSYPFLVLRTRMQTLNNEIASNYLNNERKKIKSCSFILYNIKKYGFKSLYRGIYVNLLKTIPATSITWFSYEFSMRKLQNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H085</accession>
    <name>A0A1J1H085_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">tRNA (guanine(37)-N1)-methyltransferase</fullName>
            <ecNumber evidence="10">2.1.1.228</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">M1G-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">tRNA [GM37] methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">tRNA methyltransferase 5 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00427200</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>guanosine(37) in tRNA + S-adenosyl-L-methionine = N(1)-methylguanosine(37) in tRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36899"/>
            <dbReference type="Rhea" id="RHEA-COMP:10145"/>
            <dbReference type="Rhea" id="RHEA-COMP:10147"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="EC" id="2.1.1.228"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Mitochondrion matrix</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="10">Predominantly in the mitochondria and in the nucleus.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the TRM5 / TYW2 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.228" evidence="10"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529496.1">
        <property type="nucleotide sequence ID" value="XM_028673000.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H085"/>
    <dbReference type="GeneID" id="39732804"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00427200"/>
    <dbReference type="OrthoDB" id="408788at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052906">
        <property type="term" value="F:tRNA (guanine(37)-N1)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070901">
        <property type="term" value="P:mitochondrial tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002939">
        <property type="term" value="P:tRNA N1-guanine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.110:FF:000001">
        <property type="entry name" value="tRNA (guanine(37)-N1)-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.110">
        <property type="entry name" value="Met-10+ protein-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03152">
        <property type="entry name" value="TRM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030382">
        <property type="entry name" value="MeTrfase_TRM5/TYW2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056743">
        <property type="entry name" value="TRM5-TYW2-like_MTfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056744">
        <property type="entry name" value="TRM5/TYW2-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025792">
        <property type="entry name" value="tRNA_Gua_MeTrfase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23245:SF43">
        <property type="entry name" value="TRNA (GUANINE(37)-N1)-METHYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23245">
        <property type="entry name" value="TRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02475">
        <property type="entry name" value="TRM5-TYW2_MTfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25133">
        <property type="entry name" value="TYW2_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51684">
        <property type="entry name" value="SAM_MT_TRM5_TYW2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0819">tRNA processing</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012678571" description="tRNA (guanine(37)-N1)-methyltransferase" evidence="11">
        <location>
            <begin position="18"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="domain" description="SAM-dependent methyltransferase TRM5/TYW2-type" evidence="12">
        <location>
            <begin position="270"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="359"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="397"/>
            <end position="398"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="424"/>
            <end position="425"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="618"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG96692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="703" mass="84203" checksum="8D726E2456E3D6D1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0E9</accession>
    <name>A0A1J1H0E9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein phosphatase PPM1, putative</fullName>
            <ecNumber evidence="3">3.1.3.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PPM1</name>
        <name evidence="3" type="ORF">PGAL8A_00060900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530969.1">
        <property type="nucleotide sequence ID" value="XM_028674636.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0E9"/>
    <dbReference type="GeneID" id="39729134"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00060900"/>
    <dbReference type="OMA" id="INENERW"/>
    <dbReference type="OrthoDB" id="432045at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF790">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C 22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="2">
        <location>
            <begin position="745"/>
            <end position="1039"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="528"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="306"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="528"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="549"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1079" mass="126186" checksum="4339748A062E1E9D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0L0</accession>
    <name>A0A1J1H0L0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00440200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529624.1">
        <property type="nucleotide sequence ID" value="XM_028673141.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0L0"/>
    <dbReference type="GeneID" id="39732935"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00440200"/>
    <dbReference type="OMA" id="CYFFREE"/>
    <dbReference type="OrthoDB" id="372169at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="718"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="773"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="67"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="467"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="738"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="773"/>
            <end position="789"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="797" mass="96364" checksum="ED1D48EB36B5CDE5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0P9</accession>
    <name>A0A1J1H0P9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA-intron lyase</fullName>
            <ecNumber evidence="2">4.6.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00468700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>pretRNA = a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus.</text>
            <dbReference type="EC" id="4.6.1.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the tRNA-intron endonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.16" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529909.1">
        <property type="nucleotide sequence ID" value="XM_028673459.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0P9"/>
    <dbReference type="GeneID" id="39733220"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00468700"/>
    <dbReference type="OrthoDB" id="10249562at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000214">
        <property type="term" value="C:tRNA-intron endonuclease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000213">
        <property type="term" value="F:tRNA-intron lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000379">
        <property type="term" value="P:tRNA-type intron splice site recognition and cleavage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22363">
        <property type="entry name" value="tRNA-intron_lyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036167">
        <property type="entry name" value="tRNA_intron_Endo_cat-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006677">
        <property type="entry name" value="tRNA_intron_Endonuc_cat-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006676">
        <property type="entry name" value="tRNA_splic"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21227">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21227:SF0">
        <property type="entry name" value="TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01974">
        <property type="entry name" value="tRNA_int_endo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53032">
        <property type="entry name" value="tRNA-intron endonuclease catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA intron endonuclease catalytic" evidence="4">
        <location>
            <begin position="94"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00034031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="184" mass="22363" checksum="84F6518A28FEA328" modified="2017-02-15" version="1">MRIIYKYKNEYYELLMSEENADDKVIEVFKKNTNKFDYNKIKYYEEINSDLLNFEQFSCSNIKDNKKKKGKIVKLNYKLDNALNDKNKMKLYLKYKRYFENKNYIVKSGHIYGADLLLYLSDEKYTHSIYVVYFINEQKSLRDLIQILRLSCTIKKKVILVIVNEINNFDIYNSIVYIKVYLYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1D3</accession>
    <name>A0A1J1H1D3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GYF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">GEXP15</name>
        <name evidence="3" type="ORF">PGAL8A_00491000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530133.1">
        <property type="nucleotide sequence ID" value="XM_028673707.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1D3"/>
    <dbReference type="GeneID" id="39733443"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00491000"/>
    <dbReference type="OMA" id="MIRYKND"/>
    <dbReference type="OrthoDB" id="331341at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039905">
        <property type="entry name" value="CD2BP2/Lin1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035445">
        <property type="entry name" value="GYF-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13138:SF3">
        <property type="entry name" value="CD2 ANTIGEN CYTOPLASMIC TAIL-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13138">
        <property type="entry name" value="PROTEIN LIN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55277">
        <property type="entry name" value="GYF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="796"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="457"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="801"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="837"/>
            <end position="853"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="853" mass="102053" checksum="31E2F439B82ED988" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1E6</accession>
    <name>A0A1J1H1E6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AP complex subunit sigma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00471400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the adaptor complexes small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529936.1">
        <property type="nucleotide sequence ID" value="XM_028673489.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1E6"/>
    <dbReference type="GeneID" id="39733247"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00471400"/>
    <dbReference type="OMA" id="DLIFNWQ"/>
    <dbReference type="OrthoDB" id="371463at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030117">
        <property type="term" value="C:membrane coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016635">
        <property type="entry name" value="AP_complex_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000804">
        <property type="entry name" value="Clathrin_sm-chain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11753">
        <property type="entry name" value="ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015588">
        <property type="entry name" value="AP_complex_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00989">
        <property type="entry name" value="CLAT_ADAPTOR_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AP complex mu/sigma subunit" evidence="7">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR015588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="157" mass="18197" checksum="4F84E275D57F470F" modified="2017-02-15" version="1">MIKGVLIINNSGKPRFLRFYDGSNHERQQLIIKKIHEILTKRPDNECCCFIEDNELFDSDIKVVYRHFATLYFVFIVDAMESELGILDLIQVFVQVLDANFENVCELDLIYNYEQTNYILDEIIMGGIVLETNIDTIINSINGSKKLIENESSFFGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1G6</accession>
    <name>A0A1J1H1G6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ADP-ribosylation factor-like protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00494200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530165.1">
        <property type="nucleotide sequence ID" value="XM_028673742.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1G6"/>
    <dbReference type="GeneID" id="39733475"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00494200"/>
    <dbReference type="OMA" id="MGAGMSW"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000306">
        <property type="entry name" value="ADP-ribosylation factor-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0519">Myristate</keyword>
    <keyword evidence="3 7 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="22"/>
            <end position="29"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="124"/>
            <end position="127"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00040615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG97363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="176" mass="20161" checksum="557ADD6B29A616BB" modified="2017-02-15" version="1">MLFSSIFSRLFSNKEIRILILGLDNAGKTTILNRLQLGEIVQTIPTIGFNVETVNYKNLKLQVWDLGGQSSIRPYWRCYYKNTNAIIYVIDSSDNERLTNTKYEINMILKEPDLEGVLLVIFANKQDLPNCLQISQISKDLNLTSIRDRQWAIFSTSATKNVGITEALDWLVNNIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H276</accession>
    <name>A0A1J1H276_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Magnesium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00500200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Mitochondrion inner membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530231.1">
        <property type="nucleotide sequence ID" value="XM_028673816.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H276"/>
    <dbReference type="GeneID" id="39733535"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00500200"/>
    <dbReference type="OMA" id="MELTKCY"/>
    <dbReference type="OrthoDB" id="10251508at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12823">
        <property type="entry name" value="Mrs2_Mfm1p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039204">
        <property type="entry name" value="MRS2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13890:SF0">
        <property type="entry name" value="MAGNESIUM TRANSPORTER MRS2 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13890">
        <property type="entry name" value="RNA SPLICING PROTEIN MRS2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22099">
        <property type="entry name" value="MRS2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="400"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="433"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG97430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="461" mass="54096" checksum="C8F5BCBD6C43C5A6" modified="2017-02-15" version="1">MSFESFTLMETDQNKKKNYDYNDEDYNDEDMLNSDGYERDLYTFNIKNKLVNRCKKIKVDLDNKSKKENSFNNSTFIKRERSMINDDNELRNRGRSSMSHKNEPKTKLEGILNENDYLIQLNKLKRHVVVEIFGGKCFIREYLCTEFLRRIKQCCHINYVKYNIGLINYRDCKQLLGENNNIASIEVRLNSILISLPPLTCVILHSSIFLVIKEDLIRDDLIKKLCAVSKKYTNLYKTDINMLESRPFEFCALECVFSSALEHLNAEMKLLNKDFGEIKFSLKISKYQEILSNLHNLKDPTNLLVDKVNSFIKAFHEISVNNADLKKMELTKYYFNPNANEEDNKDHTNQDLEMLLEYFDQELHQIHDQVKHLYESIINLENRIYLDLSLSRNNLIRMDIVISLINSGFGIGTLITGIFGMNLKIFLEKNDYAFGYVTGLVILLCLLTVIMSIYFFKCIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2W7</accession>
    <name>A0A1J1H2W7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">JmjC domain containing protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00526200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530487.1">
        <property type="nucleotide sequence ID" value="XM_028674101.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2W7"/>
    <dbReference type="GeneID" id="39733795"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00526200"/>
    <dbReference type="OMA" id="TNDMTND"/>
    <dbReference type="OrthoDB" id="9547406at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034647">
        <property type="term" value="F:histone H3K4me/H3K4me2/H3K4me3 demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003349">
        <property type="entry name" value="JmjN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004198">
        <property type="entry name" value="Znf_C5HC2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10694">
        <property type="entry name" value="LYSINE-SPECIFIC DEMETHYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10694:SF113">
        <property type="entry name" value="PROTEIN JUMONJI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02373">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02928">
        <property type="entry name" value="zf-C5HC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00545">
        <property type="entry name" value="JmjN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51183">
        <property type="entry name" value="JMJN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjN" evidence="4">
        <location>
            <begin position="195"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="JmjC" evidence="5">
        <location>
            <begin position="465"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="415"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1019" mass="122342" checksum="2361F70B0FC14B0A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3S3</accession>
    <name>A0A1J1H3S3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">hydroxyacylglutathione hydrolase</fullName>
            <ecNumber evidence="5">3.1.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Glyoxalase II</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00057000</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an S-(2-hydroxyacyl)glutathione + H2O = a 2-hydroxy carboxylate + glutathione + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21864"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58896"/>
            <dbReference type="ChEBI" id="CHEBI:71261"/>
            <dbReference type="EC" id="3.1.2.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite metabolism; methylglyoxal degradation; (R)-lactate from methylglyoxal: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.6" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530932.1">
        <property type="nucleotide sequence ID" value="XM_028674595.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3S3"/>
    <dbReference type="GeneID" id="39729095"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00057000"/>
    <dbReference type="OMA" id="NYIWLLQ"/>
    <dbReference type="OrthoDB" id="515692at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004416">
        <property type="term" value="F:hydroxyacylglutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019243">
        <property type="term" value="P:methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07723">
        <property type="entry name" value="hydroxyacylglutathione_hydrolase_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01374">
        <property type="entry name" value="Glyoxalase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035680">
        <property type="entry name" value="Clx_II_MBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032282">
        <property type="entry name" value="HAGH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017782">
        <property type="entry name" value="Hydroxyacylglutathione_Hdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03413">
        <property type="entry name" value="GSH_gloB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11935">
        <property type="entry name" value="BETA LACTAMASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11935:SF94">
        <property type="entry name" value="TENZING NORGAY, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16123">
        <property type="entry name" value="HAGH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005457">
        <property type="entry name" value="Glx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="11">
        <location>
            <begin position="15"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="193"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG98135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="263" mass="30708" checksum="2FF2CE91ADF57734" modified="2017-02-15" version="1">MKPSAEIHVVPVLSDNFSYIIIDEITRKAACVDPAEPEKVLRKIENLNVELEYVLCTHHHIDHSGGNVYIRNLKENIKVVGSAYEPTPGVNQKIYDEQIIHLGELIIKAIHAPCHTKGHILYYVYKVDKNEKEDVNYKPILFTGDTLFIAGCGRFFEGSAKDMFRNIEKIKSLRKETLIYCGHEYTFNNLKFALTIEKDNEYMRNKLKEVEQKIRNKKHSVPSTVEEENLINPFFRTQYYINKFNTNDEIKILDKLRELKNNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3Y8</accession>
    <name>A0A1J1H3Y8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00050100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530863.1">
        <property type="nucleotide sequence ID" value="XM_028674518.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729026"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00050100"/>
    <dbReference type="OrthoDB" id="10251508at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010297">
        <property type="entry name" value="DUF900_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36513">
        <property type="entry name" value="ABC TRANSMEMBRANE TYPE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36513:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05990">
        <property type="entry name" value="DUF900"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="651"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="709"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="742"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="799"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="349"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1154"/>
            <end position="1219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1364"/>
            <end position="1439"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="519"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1311"/>
            <end position="1356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="350"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1154"/>
            <end position="1190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1191"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1367"/>
            <end position="1380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG98066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2025" mass="240705" checksum="EF14A5A2244710A4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H437</accession>
    <name>A0A1J1H437_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RanBD1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00054900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530911.1">
        <property type="nucleotide sequence ID" value="XM_028674572.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H437"/>
    <dbReference type="GeneID" id="39729074"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00054900"/>
    <dbReference type="OMA" id="YRILCFQ"/>
    <dbReference type="OrthoDB" id="361958at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000156">
        <property type="entry name" value="Ran_bind_dom"/>
    </dbReference>
    <dbReference type="SMART" id="SM00160">
        <property type="entry name" value="RanBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50196">
        <property type="entry name" value="RANBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RanBD1" evidence="2">
        <location>
            <begin position="475"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="367"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="413"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="591" mass="69801" checksum="04428104DD8CA04D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2001-12-01" modified="2026-01-28" version="105" xmlns="https://uniprot.org/uniprot">
    <accession>Q95US9</accession>
    <name>Q95US9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 16">Bifunctional dihydrofolate reductase-thymidylate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="primary">DHFR/TS</name>
        <name evidence="21" type="ORF">PGAL8A_00090700</name>
    </gene>
    <organism evidence="20">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="journal article" date="2001" name="Exp. Parasitol." volume="99" first="111" last="114">
            <title>Plasmodium gallinaceum: cloning and characterization of dihydrofolate reductase/thymidylate synthase.</title>
            <authorList>
                <person name="Peterson D.S."/>
            </authorList>
            <dbReference type="PubMed" id="11748966"/>
            <dbReference type="DOI" id="10.1006/expr.2001.4644"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="21 22" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>(6S)-5,6,7,8-tetrahydrofolate + NADP(+) = 7,8-dihydrofolate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15009"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57451"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>dUMP + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate = 7,8-dihydrofolate + dTMP</text>
            <dbReference type="Rhea" id="RHEA:12104"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57451"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="2.1.1.45"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 16">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 5,6,7,8-tetrahydrofolate from 7,8-dihydrofolate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">In the C-terminal section; belongs to the thymidylate synthase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 16">In the N-terminal section; belongs to the dihydrofolate reductase family.</text>
    </comment>
    <dbReference type="EMBL" id="AY033582">
        <property type="protein sequence ID" value="AAK55761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q95US9"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00090700"/>
    <dbReference type="OMA" id="ILCAWNV"/>
    <dbReference type="OrthoDB" id="766at2759"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00158"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004146">
        <property type="term" value="F:dihydrofolate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004799">
        <property type="term" value="F:thymidylate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006231">
        <property type="term" value="P:dTMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00209">
        <property type="entry name" value="DHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00351">
        <property type="entry name" value="TS_Pyrimidine_HMase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.430.10:FF:000007">
        <property type="entry name" value="Bifunctional dihydrofolate reductase-thymidylate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.572.10:FF:000013">
        <property type="entry name" value="Thymidylate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="entry name" value="Dihydrofolate Reductase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.572.10">
        <property type="entry name" value="Thymidylate synthase/dCMP hydroxymethylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00008">
        <property type="entry name" value="Thymidy_synth_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012262">
        <property type="entry name" value="DHFR-TS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017925">
        <property type="entry name" value="DHFR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001796">
        <property type="entry name" value="DHFR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045097">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023451">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036926">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000398">
        <property type="entry name" value="Thymidylate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020940">
        <property type="entry name" value="Thymidylate_synthase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002497">
        <property type="entry name" value="PRK01827.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03284">
        <property type="entry name" value="thym_sym"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11548:SF2">
        <property type="entry name" value="THYMIDYLATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11548">
        <property type="entry name" value="THYMIDYLATE SYNTHASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00186">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00303">
        <property type="entry name" value="Thymidylat_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000389">
        <property type="entry name" value="DHFR-TS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00108">
        <property type="entry name" value="THYMDSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="Dihydrofolate reductase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55831">
        <property type="entry name" value="Thymidylate synthase/dCMP hydroxymethylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00075">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51330">
        <property type="entry name" value="DHFR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00091">
        <property type="entry name" value="THYMIDYLATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 16" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="10" id="KW-0521">NADP</keyword>
    <keyword evidence="9 16" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="6 16" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="11 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DHFR" evidence="19">
        <location>
            <begin position="9"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="active site" evidence="17 18">
        <location>
            <position position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR000389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR000389-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="AAK55761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="CRG93203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="589" mass="69209" checksum="39067D7E3A1ACB14" modified="2001-12-01" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2015-01-07" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A097F768</accession>
    <name>A0A097F768_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Serine hydroxymethyltransferase</fullName>
            <ecNumber evidence="8">2.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">shmt</name>
        <name evidence="11" type="synonym">SHMT</name>
        <name evidence="11" type="ORF">PGAL8A_00457300</name>
    </gene>
    <organism evidence="10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2014" name="Malar. J." volume="13" first="382" last="382">
            <title>Transcriptome sequencing and analysis of Plasmodium gallinaceum reveals polymorphisms and selection on the apical membrane antigen-1.</title>
            <authorList>
                <person name="Lauron E.J."/>
                <person name="Oakgrove K.S."/>
                <person name="Tell L.A."/>
                <person name="Biskar K."/>
                <person name="Roy S.W."/>
                <person name="Sehgal R.N."/>
            </authorList>
            <dbReference type="PubMed" id="25261185"/>
            <dbReference type="DOI" id="10.1186/1475-2875-13-382"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="11 12" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Interconversion of serine and glycine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine</text>
            <dbReference type="Rhea" id="RHEA:15481"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the SHMT family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.1" evidence="8"/>
    <dbReference type="EMBL" id="KJ722601">
        <property type="protein sequence ID" value="AIT18318.1"/>
        <property type="molecule type" value="mRNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529796.1">
        <property type="nucleotide sequence ID" value="XM_028673334.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A097F768"/>
    <dbReference type="SMR" id="A0A097F768"/>
    <dbReference type="GeneID" id="39733106"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00457300"/>
    <dbReference type="OMA" id="CQFANVQ"/>
    <dbReference type="OrthoDB" id="10265628at2759"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004372">
        <property type="term" value="F:glycine hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019264">
        <property type="term" value="P:glycine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00378">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00051">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001085">
        <property type="entry name" value="Ser_HO-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049943">
        <property type="entry name" value="Ser_HO-MeTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019798">
        <property type="entry name" value="Ser_HO-MeTrfase_PLP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039429">
        <property type="entry name" value="SHMT-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000586">
        <property type="entry name" value="PRK00011.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680">
        <property type="entry name" value="SERINE HYDROXYMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680:SF35">
        <property type="entry name" value="SERINE HYDROXYMETHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00464">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000412">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00096">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4 8" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="6 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Serine hydroxymethyltransferase-like" evidence="9">
        <location>
            <begin position="8"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000412-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="AIT18318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG96993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="442" mass="49785" checksum="176C576947A82B98" modified="2015-01-07" version="1">MFNNDSLEIFDKELFDILEDEKKRQKETINLIASENFTNLSVRECLGHCVSNKYSEGYPRKRYYGGNDYIDKIEDLCCKRALEVFNVNEEEWGVNVQSLSGSAANVQALYALVGVKGKILGMHLCSGGHLTHGFFDGKRKVSITSDLFESRLYKCNSEGYIDYDSIRDIALEFRPKVIICGYSSYPRDLDYKKFRDICDEVDAYLFADISHISSFIACNLLNNPFLYADVVTTTTHKTLRGPRSALIFFNKKRNPGIDQKINSAVFPGFQGGPHNNKIAAVACQLKEVNSDFFRKYAKQILLNSKALAKYLTDNNIDLVTNGTDNHLLLVDLRKYGITGSKLQEVCNAINVSLNKNTIPSDVDCVSPNGIRIGTPAITTRGAKENDMEFIAHILVKAIKLTVELQQIYGKKLVDFKKGLVNNDDIEKLKSEVIEWVSHLPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKX9</accession>
    <name>A0A1J1GKX9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">von Willebrand factor A domain-related protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">WARP</name>
        <name evidence="3" type="ORF">PGAL8A_00077400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525894.1">
        <property type="nucleotide sequence ID" value="XM_028670177.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKX9"/>
    <dbReference type="SMR" id="A0A1J1GKX9"/>
    <dbReference type="GeneID" id="39729299"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00077400"/>
    <dbReference type="OrthoDB" id="369041at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013040371" evidence="1">
        <location>
            <begin position="18"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="86"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="292" mass="33194" checksum="29578A823E72CB33" modified="2017-02-15" version="1">MISYLMLLLSFFAISTYEKLNVISHSSVSRLNDEKRNEKVITCVVEYIIRGDMEIDDNLFCENETSCSPSSSEASGSGDYCDNYYDITLIVEESNFVQKDYWIKGTIPFLESMIRNVRVSKDKAHMSIILFDRDQRLLVPFTDEISQDKQKLIEKVKGINDVARGPDTLYVYALEYALENVIFGDGTRSDAPKVAVLFYYGYDYGANKSLIPDIVEDYKENNIKLIIVGIGLGNKDNAYLLADCSIDDNNCANVIFKPWDFVIPAAEQVKERICNKNKSKGKSSMIQKVVYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL73</accession>
    <name>A0A1J1GL73_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="3">PPIase</shortName>
            <ecNumber evidence="3">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CYP24</name>
        <name evidence="6" type="ORF">PGAL8A_00080900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525927.1">
        <property type="nucleotide sequence ID" value="XM_028670544.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL73"/>
    <dbReference type="GeneID" id="39729333"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00080900"/>
    <dbReference type="OMA" id="XANSGPS"/>
    <dbReference type="OrthoDB" id="193499at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000033">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="5">
        <location>
            <begin position="49"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="215" mass="24422" checksum="CCBAF1CEF7071FA3" modified="2017-02-15" version="1">MKSNKNNKDNENNVNKKSDQLGLEGNDENSIIPYYLSNLLTNASNPVVFMDVNLGNHLLGRFKFELFQNIVPKTSENFRQFCTGEFKINNLPVGYKNTTFHRVIKEFMIQGGDFVNYNGSGSLSIYGENFEDENFDIKHDKEGLLSMANSGPNTNGCQFFIITKKCEWLDGKNVVFGRIIDNDSLILLKKIENVSVTPYIYKPKIPINIVECGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLG2</accession>
    <name>A0A1J1GLG2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ATPase ASNA1 homolog</fullName>
            <ecNumber evidence="8">3.6.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Arsenical pump-driving ATPase homolog</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Arsenite-stimulated ATPase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00088400</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the arsA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.-.-" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526002.1">
        <property type="nucleotide sequence ID" value="XM_028671377.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLG2"/>
    <dbReference type="GeneID" id="39729408"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00088400"/>
    <dbReference type="OMA" id="MDAPYEF"/>
    <dbReference type="OrthoDB" id="1770at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043529">
        <property type="term" value="C:GET complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071816">
        <property type="term" value="P:tail-anchored membrane protein insertion into ER membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02035">
        <property type="entry name" value="ArsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001459">
        <property type="entry name" value="ATPase ASNA1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03112">
        <property type="entry name" value="Asna1_Get3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025723">
        <property type="entry name" value="ArsA/GET3_ATPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016300">
        <property type="entry name" value="ATPase_ArsA/GET3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027542">
        <property type="entry name" value="ATPase_ArsA/GET3_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00345">
        <property type="entry name" value="GET3_arsA_TRC40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10803">
        <property type="entry name" value="ARSENICAL PUMP-DRIVING ATPASE ARSENITE-TRANSLOCATING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10803:SF3">
        <property type="entry name" value="ATPASE GET3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02374">
        <property type="entry name" value="ArsA_ATPase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ArsA/GET3 Anion-transporting ATPase-like" evidence="9">
        <location>
            <begin position="39"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="ArsA/GET3 Anion-transporting ATPase-like" evidence="9">
        <location>
            <begin position="318"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="46"/>
            <end position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="273"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG93180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="376" mass="42831" checksum="EACD93E54A1127CA" modified="2017-02-15" version="1">MNNDDSSALSCSLSLESDTCNEDEYDTNLSNLIENKTLNWIFVGGKGGVGKTTTSCSIAVQLAKRRESVLLLSTDPAHNTSDAFNQKFTNKPTLVKSFNNLYCMEIDTTFSENTAFKLNKKDIFENIIPELLQSFPGIDEALCFAELMQSIKNMKYSVIVFDTAPTGHTLRLLAFPDLLKKALGYLINIREKLKGTFNVLKNLTNNEMELENLYEKINHLNAMSSSIQSNFQNPLKTTFVCVCIPEFLSVYETERLIQELTKKNISCYNIVVNQVVFPLESPEIDVNECANLLQKINNKEIEKCFNSLIIKTRELEDVYISRRKLQSKYLMQIKNLYGNDFNIVCMPQLKNEIRGLDNISSFSEMLLESKDIPIYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLL1</accession>
    <name>A0A1J1GLL1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Asparagine-rich antigen, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00101800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526134.1">
        <property type="nucleotide sequence ID" value="XM_028672843.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729543"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00101800"/>
    <dbReference type="OMA" id="DANHEEN"/>
    <dbReference type="OrthoDB" id="372797at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="703"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1917"/>
            <end position="1936"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1972"/>
            <end position="2006"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="365"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="463"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="671"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="703"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="724"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1972"/>
            <end position="1989"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2283" mass="270869" checksum="AEF47A820A1F18FD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLZ9</accession>
    <name>A0A1J1GLZ9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mediator of RNA polymerase II transcription subunit 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MED7</name>
        <name evidence="7" type="ORF">PGAL8A_00115200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the Mediator complex subunit 7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526268.1">
        <property type="nucleotide sequence ID" value="XM_028674332.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLZ9"/>
    <dbReference type="GeneID" id="39729677"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00115200"/>
    <dbReference type="OMA" id="KYVSGYP"/>
    <dbReference type="OrthoDB" id="10253553at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070847">
        <property type="term" value="C:core mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037212">
        <property type="entry name" value="Med7/Med21-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009244">
        <property type="entry name" value="Mediatior_Med7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044888">
        <property type="entry name" value="Mediatior_Med7_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21428">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21428:SF11">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05983">
        <property type="entry name" value="Med7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140718">
        <property type="entry name" value="Mediator hinge subcomplex-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0010">Activator</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 6" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="239" mass="28965" checksum="3E6B834D62129E64" modified="2017-02-15" version="1">MTDKYVSGYPPPPYYYEEYEDANIKKIFEINNSKDNEQFIKKINEIYNIYDINENKNIKTLLAYNDIDKYDKNKCTFLMGRPPPIALKNNYNIFGMNYNVERKIEKLEPDDCLYNEKKNLKEEFIRLYKMYKDYFFDLFDDIVNNRKNDKSIIKNLIKVHINLFHILANLRYHQSVNNIINVLKIQLKRRQIAIDKMKISLLNVYNYINYVQTNFSKIKMIKDEKKNTKKEKKLKITEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM71</accession>
    <name>A0A1J1GM71_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Brl1/Brr6 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00124300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526358.1">
        <property type="nucleotide sequence ID" value="XM_028674759.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM71"/>
    <dbReference type="GeneID" id="39729768"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00124300"/>
    <dbReference type="OMA" id="INAFIVQ"/>
    <dbReference type="OrthoDB" id="5961at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006998">
        <property type="term" value="P:nuclear envelope organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040202">
        <property type="entry name" value="Brl1/Brr6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018767">
        <property type="entry name" value="Brl1/Brr6_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28136:SF1">
        <property type="entry name" value="NUCLEUS EXPORT PROTEIN BRL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28136">
        <property type="entry name" value="NUCLEUS EXPORT PROTEIN BRR6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10104">
        <property type="entry name" value="Brr6_like_C_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01042">
        <property type="entry name" value="Brr6_like_C_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="282"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="Brl1/Brr6" evidence="3">
        <location>
            <begin position="174"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="383"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="426" mass="50230" checksum="AD370B298D2F5F0A" modified="2017-02-15" version="1">MNINENKMPIIPIEESKHYSYSEENDTINLENNSNDLNSIQNFLISNVSNNGSVKCNDKKDESILKKDNINFNLIKRKKGTKKKDPYTSSHIMLGNIKNNKKINMKKRFLMNYGDQHINASELSDIKDFENSSYIHENNRMLLYDHKFREYPIRKREKKSEIIRNFFVYSPDIIQKWIRVIFNIIITSLIVVLIYFIFISVREDINKKVAIQVQNVKEESISCKKQYIAHKCGTVNLPLLNEKCEEWLKCMKTDHNLYQDISFLSAQMLGQIINAFIVQFEWKSICVIAFIFLLIFIGSNYALSIGGNRLNGDYHSLNSNNTNFPSFPYYQYYPIFPPPLNYNNSNHVDIPYMRIPSHNKIFQNNNYSRYPYQYENNYSNLNEDNTINHPVSRSKEFSEGYNSSKKDNKKSSKRLGFLKYLTRDIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM93</accession>
    <name>A0A1J1GM93_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Dynein axonemal light chain 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">DLC1</name>
        <name evidence="12" type="ORF">PGAL8A_00115700</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the dynein light chain LC1-type family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526273.1">
        <property type="nucleotide sequence ID" value="XM_028674387.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM93"/>
    <dbReference type="GeneID" id="39729682"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00115700"/>
    <dbReference type="OMA" id="ESIWRAE"/>
    <dbReference type="OrthoDB" id="266138at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000049">
        <property type="entry name" value="Dynein light chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15454:SF73">
        <property type="entry name" value="DYNEIN AXONEMAL LIGHT CHAIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15454">
        <property type="entry name" value="NISCHARIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0966">Cell projection</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-0243">Dynein</keyword>
    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7" id="KW-0505">Motor protein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG93451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="198" mass="22881" checksum="7D689364163D52ED" modified="2017-02-15" version="1">MNKPMAKGVTISHCIKNWEQKNGKKISEEEEVSFICHIPLIEKLDNSINSLEKCKRLSLSTNRIEKLIPMSGLKNIEILSLGRNCIKKFQFLEDISGTLKQLWMSYNSIDKLDNLQSLKKLQVLYLFHNKIRSIEEIDKLNTLPELVELGLKGNPIYEGKTNEYMKLVILKKLPQLKIVDNETITEKQRNDALTVEII</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMK0</accession>
    <name>A0A1J1GMK0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00129500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526410.1">
        <property type="nucleotide sequence ID" value="XM_028674817.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMK0"/>
    <dbReference type="GeneID" id="39729820"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00129500"/>
    <dbReference type="OMA" id="NIYVCSY"/>
    <dbReference type="OrthoDB" id="364553at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="672"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="439"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="677"/>
            <end position="718"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1172" mass="140788" checksum="D1D2F3294B3D4C66" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMK7</accession>
    <name>A0A1J1GMK7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L19, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00138600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526502.1">
        <property type="nucleotide sequence ID" value="XM_028674919.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMK7"/>
    <dbReference type="GeneID" id="39729910"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00138600"/>
    <dbReference type="OMA" id="MPKIHAG"/>
    <dbReference type="OrthoDB" id="432645at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.790:FF:000005">
        <property type="entry name" value="Mitochondrial ribosomal protein L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001857">
        <property type="entry name" value="Ribosomal_bL19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038657">
        <property type="entry name" value="Ribosomal_bL19_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15680:SF9">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL19M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15680">
        <property type="entry name" value="RIBOSOMAL PROTEIN L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01245">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00061">
        <property type="entry name" value="RIBOSOMALL19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="316" mass="38635" checksum="83BA22D7299663AB" modified="2017-02-15" version="1">MIKRYIRTKIITSLSKYKCYNISNEKTSKCWPNIDCIDKEEENITKKSEKEKKKTIPYYKNYIHDFYNRQLMHNLHLIEMNKMNKLRNFKMPKIHAGDLIEVKYELSRSQQTFAIFQGYCVEIRKKRLDSSFIVKNIFDGVGVEQLIPFYSPRILYVKIVKSLYNLNEENMKKYYQINKPITRDYRYMWQYNFRGKYERPRGQHKPGIRSIEPKIRRRLAKLKKKYMKRRIESNLSSYIFGGIYSQYTRKRTRLVRAEIYRRMLIYALDEENRRKQKLHKRREKEKWNNFKINRNKGDNAFMAIPANHPLNSNRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMM9</accession>
    <name>A0A1J1GMM9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00132500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526442.1">
        <property type="nucleotide sequence ID" value="XM_028674852.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729850"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00132500"/>
    <dbReference type="OrthoDB" id="384640at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1612" mass="192674" checksum="27FD0EFAAA2EA20A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMU9</accession>
    <name>A0A1J1GMU9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00139800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526514.1">
        <property type="nucleotide sequence ID" value="XM_028674932.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMU9"/>
    <dbReference type="GeneID" id="39729922"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00139800"/>
    <dbReference type="OMA" id="YIVENIY"/>
    <dbReference type="OrthoDB" id="198735at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="280" mass="33507" checksum="D3F841C9197DDBA9" modified="2017-02-15" version="1">MLRLNNVRFFFKSKVRFSGGKQHPKWVVKDKEKYNVFTYDNSYYGENFRYNNFILHIRSYKYYINYIVENIYKTLKCCCRFCFNPIKNFILKHNPDIRYQLIALLAFLGTTSIITTYHNNIYQNIIDVTNMLELGVVDDMKENNFFDTHSELQNKNIDDYSQDHERLTDLWEKALKDATQKNSFNQLCQYLIIKDDESIVNFKPKHIWRYNMIPYGENNPDTKTFAIPSSEKPFRSFALNFTYNNLSGNWGDYVDRRDNKGSLLRPSRYMFTDVLIPATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN31</accession>
    <name>A0A1J1GN31_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00138300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526499.1">
        <property type="nucleotide sequence ID" value="XM_028674916.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729907"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00138300"/>
    <dbReference type="OMA" id="IFFINNC"/>
    <dbReference type="OrthoDB" id="372051at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="99"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="655"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="956"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="209"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1715"/>
            <end position="1776"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1872"/>
            <end position="1915"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2348"/>
            <end position="2399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="214"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="226"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1752"/>
            <end position="1766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1872"/>
            <end position="1894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1905"/>
            <end position="1915"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2951" mass="355070" checksum="2173007889C51819" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN33</accession>
    <name>A0A1J1GN33_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Conserved oligomeric Golgi complex subunit 4 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00144500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526561.1">
        <property type="nucleotide sequence ID" value="XM_028674984.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN33"/>
    <dbReference type="GeneID" id="39729969"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00144500"/>
    <dbReference type="OMA" id="CRSINMN"/>
    <dbReference type="OrthoDB" id="47059at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048682">
        <property type="entry name" value="COG4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048684">
        <property type="entry name" value="COG4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24016">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24016:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20662">
        <property type="entry name" value="COG4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Conserved oligomeric Golgi complex subunit 4 C-terminal" evidence="2">
        <location>
            <begin position="794"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1038" mass="124232" checksum="92108F0B06E9CD15" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN81</accession>
    <name>A0A1J1GN81_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Syntaxin binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00142300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the STXBP/unc-18/SEC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526539.1">
        <property type="nucleotide sequence ID" value="XM_028674960.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN81"/>
    <dbReference type="GeneID" id="39729947"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00142300"/>
    <dbReference type="OMA" id="PFTRPHT"/>
    <dbReference type="OrthoDB" id="2228at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.830.10">
        <property type="entry name" value="Syntaxin Binding Protein 1, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043154">
        <property type="entry name" value="Sec-1-like_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043127">
        <property type="entry name" value="Sec-1-like_dom3a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001619">
        <property type="entry name" value="Sec1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027482">
        <property type="entry name" value="Sec1-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036045">
        <property type="entry name" value="Sec1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11679">
        <property type="entry name" value="VESICLE PROTEIN SORTING-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00995">
        <property type="entry name" value="Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005715">
        <property type="entry name" value="VPS45_Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56815">
        <property type="entry name" value="Sec1/munc18-like (SM) proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="616" mass="72584" checksum="1BB6E9C7C3AB2788" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNM1</accession>
    <name>A0A1J1GNM1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Alpha/beta hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00158600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526699.1">
        <property type="nucleotide sequence ID" value="XM_028675138.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNM1"/>
    <dbReference type="GeneID" id="39730111"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00158600"/>
    <dbReference type="OMA" id="FKWFFSE"/>
    <dbReference type="OrthoDB" id="10249433at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="284"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="592" mass="69411" checksum="153655E500AA0060" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNR2</accession>
    <name>A0A1J1GNR2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">CCR4-NOT transcription complex subunit 5, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">NOT5</name>
        <name evidence="6" type="ORF">PGAL8A_00382300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CNOT2/3/5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526940.1">
        <property type="nucleotide sequence ID" value="XM_028670160.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNR2"/>
    <dbReference type="GeneID" id="39732353"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00382300"/>
    <dbReference type="OMA" id="FETHTKE"/>
    <dbReference type="OrthoDB" id="293823at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030015">
        <property type="term" value="C:CCR4-NOT core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.1020">
        <property type="entry name" value="CCR4-NOT complex subunit 2/3/5, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038635">
        <property type="entry name" value="CCR4-NOT_su2/3/5_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040168">
        <property type="entry name" value="Not2/3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007282">
        <property type="entry name" value="NOT2/3/5_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23326">
        <property type="entry name" value="CCR4 NOT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04153">
        <property type="entry name" value="NOT2_3_5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="NOT2/NOT3/NOT5 C-terminal" evidence="5">
        <location>
            <begin position="51"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG94119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="183" mass="22237" checksum="2EA207778B767792" modified="2017-02-15" version="1">MNEKKNDENKNNSIKKSEKKKKNNQLSSSAQKLLEKNSLKLQELIEESYKNCIKKSDRDQFRQYTPRMLWGNPCKYFPTTPLSEFQSPQLFEKFHLDTLFFIFYYQPGTYQQHLAAKELKKKSWKYHKKYTTWFLPHDNNVRVINDKMEQGTYLSFDYESTWSKQLKKDFSFEYIYLEDEITV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNV5</accession>
    <name>A0A1J1GNV5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00378900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526906.1">
        <property type="nucleotide sequence ID" value="XM_028670123.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNV5"/>
    <dbReference type="GeneID" id="39732319"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00378900"/>
    <dbReference type="OMA" id="HMHQERK"/>
    <dbReference type="OrthoDB" id="377743at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048018">
        <property type="term" value="F:receptor ligand activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37458">
        <property type="entry name" value="THISBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37458:SF1">
        <property type="entry name" value="THISBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="548"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="832" mass="98441" checksum="2FF6998DB16E24C4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNY5</accession>
    <name>A0A1J1GNY5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aldehyde reductase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00171100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526825.1">
        <property type="nucleotide sequence ID" value="XM_028670032.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNY5"/>
    <dbReference type="GeneID" id="39730238"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00171100"/>
    <dbReference type="OMA" id="IGLESWR"/>
    <dbReference type="OrthoDB" id="2310150at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19094">
        <property type="entry name" value="AKR_Tas-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF4">
        <property type="entry name" value="NAD(P)-LINKED OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012068583" evidence="3">
        <location>
            <begin position="18"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="373"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="528"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="472"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="472"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="482"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="795" mass="95737" checksum="E0CE7FC8EF08CAEC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP12</accession>
    <name>A0A1J1GP12_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00385300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526970.1">
        <property type="nucleotide sequence ID" value="XM_028670193.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP12"/>
    <dbReference type="GeneID" id="39732383"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00385300"/>
    <dbReference type="OMA" id="CCADFCS"/>
    <dbReference type="OrthoDB" id="381124at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="323"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="408" mass="49132" checksum="35AE439E44CA31EF" modified="2017-02-15" version="1">MTKILIFFFTLSSFFSYIFTCIHVEDTFKIKLKKINTGDFLKICCNNFCSYLKYDVTKKTYLLIKKNVALYSCTNMMKLYYSNGHSYFTHFLFVNIDQVIEFIDSFEEEKKKFLFWKPFFELIEIIKEKKYIYSPLGYYQKNNFNSKNKLNYYNNNELANHTKKYSICEEKKKKEEDTNTKNDEIFEKCKDYLKKHNKNNIYNMGSLIQNFREIIVEMKKEKIDIFGNSKHVANKFGYSNNIINNNNKNSSNIVEKYNSFHKIWENYLKKNIFIYNPIFLFLFEDQNIWNFSIKEIDTSLDTNYKKKGNMQKKNYKEFLRKEIVLFLFIILTILVQIFLKRKKCKIKAGKKYTKNKYRITQNRLAEIHVEYNNKIQTNVGSKIKDITDEDLINLMAHNKAEIIIVCQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP77</accession>
    <name>A0A1J1GP77_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WD repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00380400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526921.1">
        <property type="nucleotide sequence ID" value="XM_028670139.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732334"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00380400"/>
    <dbReference type="OrthoDB" id="338622at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049916">
        <property type="entry name" value="WDR72-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44099">
        <property type="entry name" value="RABCONNECTIN-3B, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44099:SF4">
        <property type="entry name" value="RABCONNECTIN-3B, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1811"/>
            <end position="1832"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1844"/>
            <end position="1863"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1883"/>
            <end position="1902"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="2132"/>
            <end position="2151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2318" mass="274998" checksum="455EA4813D6E0D42" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPD4</accession>
    <name>A0A1J1GPD4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mitochondrial ribosomal protein L27, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00400200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527119.1">
        <property type="nucleotide sequence ID" value="XM_028670359.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPD4"/>
    <dbReference type="GeneID" id="39732532"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00400200"/>
    <dbReference type="OMA" id="TQYIKPP"/>
    <dbReference type="OrthoDB" id="1867012at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001684">
        <property type="entry name" value="Ribosomal_bL27"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL27M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893">
        <property type="entry name" value="RIBOSOMAL PROTEIN L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01016">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110324">
        <property type="entry name" value="Ribosomal L27 protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="285" mass="34074" checksum="BBB4CE05034323CC" modified="2017-02-15" version="1">MTSLFQISSIFNKINKKQYFNYFNLINKKSLLMNDIKLRYISTGMNNFNLIINKNIKNNISKFNLIDKKRIFMNNIRQCNVYTNMSIYKQNDNGNCFLKIFKRNKMVKTSSYRRKSRSSPNGQGQKAKIGIKRLSGEYVKTGQMLVKQRKIIAFNYEKKTRKRNFKYYPGENVKVSKNTSLIALTNGRVKYTFHVLQNILIVNILPEELEELKEEDLYRYRTEHVKSFEENRSLVYLRMKNIITFPKFKNTQYIKPPLKPQFLTKYDIYDNPTLQEVPILYHKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPH9</accession>
    <name>A0A1J1GPH9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RecQ mediated genome instability protein 1 OB-fold domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00391600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527033.1">
        <property type="nucleotide sequence ID" value="XM_028670263.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPH9"/>
    <dbReference type="GeneID" id="39732446"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00391600"/>
    <dbReference type="OrthoDB" id="380820at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.770">
        <property type="entry name" value="RecQ-mediated genome instability protein Rmi1, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042470">
        <property type="entry name" value="RMI1_N_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013894">
        <property type="entry name" value="RMI1_OB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08585">
        <property type="entry name" value="RMI1_N_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecQ mediated genome instability protein 1 OB-fold" evidence="2">
        <location>
            <begin position="54"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="497"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1005" mass="123019" checksum="7D4772B8D4C130A8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPU8</accession>
    <name>A0A1J1GPU8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AP complex subunit sigma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00193300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the adaptor complexes small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000029">
        <property type="protein sequence ID" value="CRG94535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527350.1">
        <property type="nucleotide sequence ID" value="XM_028670615.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPU8"/>
    <dbReference type="GeneID" id="39730458"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00193300"/>
    <dbReference type="OMA" id="YVRNQAW"/>
    <dbReference type="OrthoDB" id="371463at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd14832">
        <property type="entry name" value="AP4_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000010">
        <property type="entry name" value="AP complex subunit sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016635">
        <property type="entry name" value="AP_complex_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11753">
        <property type="entry name" value="ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015588">
        <property type="entry name" value="AP_complex_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AP complex mu/sigma subunit" evidence="7">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR015588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="146" mass="17488" checksum="35F68763FAE825CD" modified="2017-02-15" version="1">MIEFLLMVNKQGQTRLSQYYNNLSIEEKTILEGELIRKCLSRVDYQCSFLQYREYKIIYRRYASLYLIVGVTNKDVNEFAILEMIHNIIEILDKYYENVCELDIMFNIDKTHFIIDEIICNGEICDMNKTNVLRPILLMDKFSLKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ82</accession>
    <name>A0A1J1GQ82_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00197100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527391.1">
        <property type="nucleotide sequence ID" value="XM_028670661.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730498"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00197100"/>
    <dbReference type="OMA" id="LYIFVSY"/>
    <dbReference type="OrthoDB" id="428850at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="599"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="630"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="866"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1165"/>
            <end position="1192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1733"/>
            <end position="1749"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1769"/>
            <end position="1793"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="2970"/>
            <end position="2987"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="3131"/>
            <end position="3151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="3477"/>
            <end position="3496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="3528"/>
            <end position="3547"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="3639"/>
            <end position="3656"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="3677"/>
            <end position="3696"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="3731"/>
            <end position="3747"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="3756"/>
            <end position="3774"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="3876"/>
            <end position="3894"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="3906"/>
            <end position="3925"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1279"/>
            <end position="1299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2806"/>
            <end position="2825"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2589"/>
            <end position="2616"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3266"/>
            <end position="3365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1286"/>
            <end position="1299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2806"/>
            <end position="2819"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="4081" mass="497268" checksum="6C9F3D17FBBDA353" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQM8</accession>
    <name>A0A1J1GQM8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Armadillo repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00216000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the importin alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527578.1">
        <property type="nucleotide sequence ID" value="XM_028670869.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQM8"/>
    <dbReference type="GeneID" id="39730687"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00216000"/>
    <dbReference type="OrthoDB" id="29145at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23316">
        <property type="entry name" value="IMPORTIN ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="674" mass="76794" checksum="0D4510FF797E39F4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQS1</accession>
    <name>A0A1J1GQS1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00133600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526453.1">
        <property type="nucleotide sequence ID" value="XM_028674864.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQS1"/>
    <dbReference type="GeneID" id="39729861"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00133600"/>
    <dbReference type="OMA" id="AKIFQFD"/>
    <dbReference type="OrthoDB" id="441329at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00105">
        <property type="entry name" value="KH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="51"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="142"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="318"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="4">
        <location>
            <begin position="399"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="235"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="531"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="682" mass="76640" checksum="361142B052B31EA4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQT1</accession>
    <name>A0A1J1GQT1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00221600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527634.1">
        <property type="nucleotide sequence ID" value="XM_028670930.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQT1"/>
    <dbReference type="GeneID" id="39730743"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00221600"/>
    <dbReference type="OMA" id="EQIVCNM"/>
    <dbReference type="OrthoDB" id="410044at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36856">
        <property type="entry name" value="OS07G0175200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36856:SF1">
        <property type="entry name" value="OS07G0175200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="73" mass="8393" checksum="F000582966A0A564" modified="2017-02-15" version="1">MSEFKVGSKLKEQVVCNMQPLILCLHKNNDDITKCIDEINIFEKTCSKKVNYVHDRIGLDDTRNTLYTGKKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR43</accession>
    <name>A0A1J1GR43_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein MGET</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00229400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527711.1">
        <property type="nucleotide sequence ID" value="XM_028671016.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR43"/>
    <dbReference type="GeneID" id="39730821"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00229400"/>
    <dbReference type="OMA" id="CKELQCI"/>
    <dbReference type="OrthoDB" id="386428at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="336"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="56"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="119"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="433" mass="50999" checksum="E6D42A60FAD7A130" modified="2017-02-15" version="1">MSKIKERKLNKIPEYPLKKETKDNKIKKIFNKNLFSISNGNKNGVNIEEDNIINQIKELNLILLENKDEINNLKQENESFSSQIINFIKKCKELQHIGIEKEEEITKLKQSEKKILIELNKFKNEQEISEEKIKNLTSIDKNKNIHISDLNEQINVLKKKLDDKNSEINMLNENIKNLNQKIIILQSESTKNKQDVNNNLKRQNEMNENINAKESKINTLEEKIKKYNQLMKEKIEEIENCKKKIQQQNTRITYLMEKIQNLEKEKKNDKEKIKKNMEYIKILKKKNNKREEKNEEYNMMEKKKEQEDAIFNSQFYNLNKKKNKNKNNLEYNFVVPTNGSSKIKGGSRSNSSSSSSSSDDDGEIVNFTNKYNLNKKLNKDINSRINKNKSNVNNINDVNKNVPLKKKNTSKNTKYCVNQEIVKKLNKEDTCSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR46</accession>
    <name>A0A1J1GR46_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Kinetochore protein NDC80</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">NDC80</name>
        <name evidence="13" type="ORF">PGAL8A_00144900</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the NDC80 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Chromosome</location>
            <location evidence="10">Centromere</location>
            <location evidence="10">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the NDC80/HEC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526565.1">
        <property type="nucleotide sequence ID" value="XM_028674988.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR46"/>
    <dbReference type="GeneID" id="39729973"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00144900"/>
    <dbReference type="OMA" id="PSHKFQK"/>
    <dbReference type="OrthoDB" id="7459479at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031262">
        <property type="term" value="C:Ndc80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051315">
        <property type="term" value="P:attachment of mitotic spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.30">
        <property type="entry name" value="Ncd80 complex, Ncd80 subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005550">
        <property type="entry name" value="Kinetochore_Ndc80"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055260">
        <property type="entry name" value="Ndc80_CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038273">
        <property type="entry name" value="Ndc80_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10643">
        <property type="entry name" value="KINETOCHORE PROTEIN NDC80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10643:SF2">
        <property type="entry name" value="KINETOCHORE PROTEIN NDC80 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03801">
        <property type="entry name" value="Ndc80_HEC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="9 10" id="KW-0137">Centromere</keyword>
    <keyword evidence="2 10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 10" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="4 10" id="KW-0498">Mitosis</keyword>
    <keyword evidence="7 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinetochore protein Ndc80 CH" evidence="12">
        <location>
            <begin position="57"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="216"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="492"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG93743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="590" mass="69865" checksum="3FADBE1F897EA90A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR80</accession>
    <name>A0A1J1GR80_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cleavage stimulation factor 50 kDa subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00148900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526605.1">
        <property type="nucleotide sequence ID" value="XM_028675033.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR80"/>
    <dbReference type="GeneID" id="39730013"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00148900"/>
    <dbReference type="OMA" id="LYVHPCG"/>
    <dbReference type="OrthoDB" id="71437at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005848">
        <property type="term" value="C:mRNA cleavage stimulating factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044633">
        <property type="entry name" value="CstF1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44133">
        <property type="entry name" value="CLEAVAGE STIMULATION FACTOR SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44133:SF2">
        <property type="entry name" value="CLEAVAGE STIMULATION FACTOR SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 7" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="209"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="315"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="366"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="493" mass="57198" checksum="4BF538DA565F1F28" modified="2017-02-15" version="1">MKEYNANNSFSLNNVISKNDNVITNNDNDSKFVKSERDKNYDENIDNNGFNNFEERKNISIDKIGFYEIVLKQLLDDNLIDSFNVLKKELNLQENKNVENDYLFNLYAKNIYKSSEPNNEKNIESLVNIESMIKRVKSFNDSVLNYDIKSENIKRLYRYEINDHIELIHRNKCICCDTNYSHNILCSGGLDNVVKIAKIYDKKKKVYNIEKHNGKVNCVKFHPFKNILFSASDDCTVQIFDLNKLLKKKKLANKVNINENINETYKNILIQDKNPFICLYVHPCGDFLYTSNKNENILKMYDLETLTCYISLDKNSFHTSSINSISGTSDGSIYSSVSDDGHIKFWDGHNSKLIHTQCNAHNGYSVQSVKFNKSNFYILTSGLDGQTKIWDIRNFKSLFTFGNGLSCSFNKSIFMNNESFIANIIHTSNNLSSSHFYIYNSYFGNMEYNIQNIHNDQISDIVNAKDSLNVHTASYDYVCKTIKIEQKYLDDYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRG0</accession>
    <name>A0A1J1GRG0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">26S proteasome regulatory subunit RPN2, putative</fullName>
            <ecNumber evidence="9">3.4.25.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">RPN2</name>
        <name evidence="9" type="ORF">PGAL8A_00225700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the proteasome subunit S1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.25.1" evidence="9"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527675.1">
        <property type="nucleotide sequence ID" value="XM_028670975.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRG0"/>
    <dbReference type="GeneID" id="39730784"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00225700"/>
    <dbReference type="OMA" id="IMFGRQE"/>
    <dbReference type="OrthoDB" id="261572at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034515">
        <property type="term" value="C:proteasome storage granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042176">
        <property type="term" value="P:regulation of protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000017">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016642">
        <property type="entry name" value="26S_Psome_Rpn2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004155">
        <property type="entry name" value="PBS_lyase_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002015">
        <property type="entry name" value="Proteasome/cyclosome_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048570">
        <property type="entry name" value="PSMD1_RPN2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040623">
        <property type="entry name" value="RPN2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10943">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10943:SF2">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13646">
        <property type="entry name" value="HEAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01851">
        <property type="entry name" value="PC_rep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18004">
        <property type="entry name" value="RPN2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21505">
        <property type="entry name" value="RPN2_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015947">
        <property type="entry name" value="26S_Psome_Rpn2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00567">
        <property type="entry name" value="EZ_HEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4 9" id="KW-0647">Proteasome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="26S proteasome non-ATPase regulatory subunit 1/RPN2 N-terminal" evidence="8">
        <location>
            <begin position="14"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="26S proteasome non-ATPase regulatory subunit 1/RPN2 N-terminal" evidence="8">
        <location>
            <begin position="169"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="26S proteasome regulatory subunit RPN2 C-terminal" evidence="7">
        <location>
            <begin position="931"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="993"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1029"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="359"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="993"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1076"/>
            <end position="1086"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR015947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF18004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF21505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1162" mass="131773" checksum="88543C2101300F5E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRG7</accession>
    <name>A0A1J1GRG7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA-directed DNA polymerase</fullName>
            <ecNumber evidence="3">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">PGAL8A_00158800</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526701.1">
        <property type="nucleotide sequence ID" value="XM_028675140.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730113"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00158800"/>
    <dbReference type="OMA" id="YYYASLT"/>
    <dbReference type="OrthoDB" id="10060449at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008622">
        <property type="term" value="C:epsilon DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008310">
        <property type="term" value="F:single-stranded DNA 3'-5' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006287">
        <property type="term" value="P:base-excision repair, gap-filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045004">
        <property type="term" value="P:DNA replication proofreading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006272">
        <property type="term" value="P:leading strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006297">
        <property type="term" value="P:nucleotide-excision repair, DNA gap filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000010">
        <property type="entry name" value="DNA polymerase epsilon catalytic subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.690:FF:000009">
        <property type="entry name" value="DNA polymerase epsilon catalytic subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1600.10:FF:000012">
        <property type="entry name" value="DNA polymerase epsilon catalytic subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.132.60:FF:000009">
        <property type="entry name" value="DNA polymerase epsilon, catalytic subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.60">
        <property type="entry name" value="DNA polymerase family B, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006133">
        <property type="entry name" value="DNA-dir_DNA_pol_B_exonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042087">
        <property type="entry name" value="DNA_pol_B_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013697">
        <property type="entry name" value="DNA_pol_e_suA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029703">
        <property type="entry name" value="POL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055191">
        <property type="entry name" value="POL2_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054475">
        <property type="entry name" value="Znf-DPOE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10670">
        <property type="entry name" value="DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10670:SF0">
        <property type="entry name" value="DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03104">
        <property type="entry name" value="DNA_pol_B_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22634">
        <property type="entry name" value="POL2_thumb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22912">
        <property type="entry name" value="zf-DPOE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23250">
        <property type="entry name" value="zf_DPOE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01159">
        <property type="entry name" value="DUF1744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="16" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0235">DNA replication</keyword>
    <keyword evidence="14" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="12" id="KW-0408">Iron</keyword>
    <keyword evidence="13" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNA polymerase epsilon catalytic subunit A C-terminal" evidence="18">
        <location>
            <begin position="1874"/>
            <end position="2349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1542"/>
            <end position="1561"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="214"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="1544"/>
            <end position="1561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM01159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="CRG93880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2736" mass="325729" checksum="690054EBB4B5B688" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRI4</accession>
    <name>A0A1J1GRI4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00230400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the proteasome complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase T1B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527721.1">
        <property type="nucleotide sequence ID" value="XM_028671027.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRI4"/>
    <dbReference type="GeneID" id="39730831"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00230400"/>
    <dbReference type="OMA" id="MKRDHDK"/>
    <dbReference type="OrthoDB" id="268428at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005839">
        <property type="term" value="C:proteasome core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010498">
        <property type="term" value="P:proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03758">
        <property type="entry name" value="proteasome_beta_type_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035206">
        <property type="entry name" value="Proteasome_beta2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 4 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="195" mass="22825" checksum="A98E3B33D941B596" modified="2017-02-15" version="1">MDTLIGLKGKNFVILAADTYSINSIVKLKNDDKTKFYDINGNKCLLLGGSIGDRIQFGEFIRKNVHLYQFQNSTDLFVKSFAYFTRRNLAYYLRRNPYEVNCLIAGYDNKDGYQLYWCDYLSNMDAVNKGAHGYGAYLVNAILDKYYHENINLEEALAIFQKCFEELKQRFLLTQINYELRIMSDNKIQKQYVTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRL4</accession>
    <name>A0A1J1GRL4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">MSP7-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00246500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527879.1">
        <property type="nucleotide sequence ID" value="XM_028671204.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRL4"/>
    <dbReference type="GeneID" id="39730993"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00246500"/>
    <dbReference type="OMA" id="NTEEFNG"/>
    <dbReference type="OrthoDB" id="387367at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024781">
        <property type="entry name" value="MSP_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12948">
        <property type="entry name" value="MSP7_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009618932" evidence="2">
        <location>
            <begin position="22"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="domain" description="Merozoite surface protein C-terminal" evidence="3">
        <location>
            <begin position="932"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="847"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="433"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="479"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="514"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="552"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="587"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="602"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="623"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="676"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="731"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="750"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="770"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="862"/>
            <end position="876"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1059" mass="120697" checksum="41B38D98D04243CB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRY7</accession>
    <name>A0A1J1GRY7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00259900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528007.1">
        <property type="nucleotide sequence ID" value="XM_028671346.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRY7"/>
    <dbReference type="GeneID" id="39731128"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00259900"/>
    <dbReference type="OMA" id="YANDEHV"/>
    <dbReference type="OrthoDB" id="372600at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="118" mass="14156" checksum="1E12FBDAC4361086" modified="2017-02-15" version="1">MDDNKNLDFGKKKENIKFSKFVTSLSFMKKNRDEEENVKKKIKYSNDDHVWILKEFEESGNEYLRNKLSQKNKNNVSLNCMGRKSYNNYNNYVNLYNIEIQKFITSVKKNKPINSLRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS66</accession>
    <name>A0A1J1GS66_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Zinc finger protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00385600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526973.1">
        <property type="nucleotide sequence ID" value="XM_028670196.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS66"/>
    <dbReference type="GeneID" id="39732386"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00385600"/>
    <dbReference type="OrthoDB" id="1306014at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20908">
        <property type="entry name" value="SUF4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23215:SF0">
        <property type="entry name" value="BUB3-INTERACTING AND GLEBS MOTIF-CONTAINING PROTEIN ZNF207"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23215">
        <property type="entry name" value="ZINC FINGER PROTEIN 207"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="362"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="374"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="389"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="503" mass="55645" checksum="5C25109DEC716A2C" modified="2017-02-15" version="1">MGRKKRKVNIELKPFCYYCDREFDDEKILIQHQKAKHFKCLQCNRKLDIANGLVVHMLQVHKTNLKVVPNALPKRNDPEIIIRGMNGVPPEIIEENLNKLKQKLGDKDIKRQQRVNWAQVAMAPTMEQFLQQAQTGNFTFPGFNSPILPPHNLLSNSTDLKKKNMSSAPLYLPNNNLNMMQPPLSTNLYSSNNQQNLTIPNIPFHVSSNIPPNNMNSSTPTGIPSNIPPPTPPNISHKYPQNIHLSGSFMPPNLPTNIPQTHPICIPPGISPPIPPSTPPTTPSAIPPVIPSSVHLSVPPSAPPTMPPSVLPTIPSVMPPTGPPPNETSIISTNLSSNAQTGKGTTIPGININNNVNKTNGIQHNNPPNEGINHHIMNNINSSSMNNMQTSKQSSLEMSPNNYDIHTNSNDTQKNETNNSTKEINGTINNNSKIEEKDKTNIEGENKIQKSKDKENTDSEYLYDNSISTTIKLSIPPPNPPSIPPTGDLKLNYSETVIFFFFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSD0</accession>
    <name>A0A1J1GSD0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00261700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528025.1">
        <property type="nucleotide sequence ID" value="XM_028671365.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSD0"/>
    <dbReference type="GeneID" id="39731146"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00261700"/>
    <dbReference type="OMA" id="IYFKYEW"/>
    <dbReference type="OrthoDB" id="375750at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012927146" evidence="1">
        <location>
            <begin position="20"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="251" mass="30792" checksum="FB8FBFA6F481F060" modified="2017-02-15" version="1">MVKLHFLLFFFFLINYINGFVYKNKKSRTKRFFNGLKKKYKNFKERYKKSFKLKEKDVVGDYQIKAYFNFDDKFEKDFKWKLFYIYSRRGKSLCQYFKLRKKYKQKYESKSFSFKKYFSDVNFVYTQFTLEYTHIKFNVNLEEKNKILVSYNPNITDKIIKSLTNLINGQDVKRNKKPPSWKLTFNFVTGKKRLIISIPSEVPGLFFTFYYEIVAYKYYFSNPFSYFGDIYFRFGGNLKKYKVGYFDFSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSD3</accession>
    <name>A0A1J1GSD3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TBC domain protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00259500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528003.1">
        <property type="nucleotide sequence ID" value="XM_028671341.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSD3"/>
    <dbReference type="GeneID" id="39731124"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00259500"/>
    <dbReference type="OMA" id="SCYNIFN"/>
    <dbReference type="OrthoDB" id="26371at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.80:FF:000041">
        <property type="entry name" value="TBC domain containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000028">
        <property type="entry name" value="TBC domain containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.750">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957:SF26">
        <property type="entry name" value="LD44506P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="51"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="72"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="347" mass="41164" checksum="C39765D4903A8A0B" modified="2017-02-15" version="1">MKLEGKNEDKKDEVEQKNISQRMKKLCSILNSPIIDINELKNILWSGIPDEMPFNVREKCWKLALGYLPLNTEDTDKVLKKKRDEYENLKKQYYNKNKLSEEELKILRQIKVDIPRTKSCYNIFINKKIQQISEHVLFIYSVRHPACGYVQGINDLITPFLIVFLRPLVTKKEISSDDIDKVTDDELKNVESDLYFCLSKLLEQIQDNYTFGQPGIQRAIIKVKEIVKRIDISLFNHIYNNNIDFIQFSFRWVNCLLLREFPINISVRLLDTYISDICDIFTDFHPYICAVFLVHWSKHLKEMDFQQMLLFMQRFPTQNWKIQDIESILSEAFVLKNAFQSSPKHFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSP2</accession>
    <name>A0A1J1GSP2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00266300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000035">
        <property type="protein sequence ID" value="CRG95460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528271.1">
        <property type="nucleotide sequence ID" value="XM_028671638.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSP2"/>
    <dbReference type="GeneID" id="39731192"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00266300"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="110" mass="12609" checksum="A62A77CFE4830C59" modified="2017-02-15" version="1">MDKQLNNLFGNSNNPVMPNCQSYEMAMLIAVILAAFTVLLSLLPMFYQSSSLNRELKEINTWNKKLDESLHSKDGDGIETMGPEYLVNPEDELLYGRKNEIEDSDEEYEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSZ5</accession>
    <name>A0A1J1GSZ5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00387500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526992.1">
        <property type="nucleotide sequence ID" value="XM_028670218.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSZ5"/>
    <dbReference type="GeneID" id="39732405"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00387500"/>
    <dbReference type="OMA" id="HIWIMSF"/>
    <dbReference type="OrthoDB" id="372938at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12791">
        <property type="entry name" value="GOLGI SNARE BET1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="8">
        <location>
            <begin position="21"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="31"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="114" mass="13832" checksum="8362D4D4CA52639A" modified="2017-02-15" version="1">MDFNSRKKKKNSNDFYNENINIYLEENDNYILDLEKKVQNLKLIGSNLRDEVKTSNSLLDNLSDRMDNVNKKLTGVYKRVKNILKTKGNKYMVYLILFFLFLLFFMHYLYRKNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT13</accession>
    <name>A0A1J1GT13_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Zinc finger protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00287500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528486.1">
        <property type="nucleotide sequence ID" value="XM_028671878.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT13"/>
    <dbReference type="GeneID" id="39731408"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00287500"/>
    <dbReference type="OMA" id="KCYEHKP"/>
    <dbReference type="OrthoDB" id="74807at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21437">
        <property type="entry name" value="zf-HIT_ZNHIT1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039723">
        <property type="entry name" value="Vps71/ZNHIT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007529">
        <property type="entry name" value="Znf_HIT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13093">
        <property type="entry name" value="ZINC FINGER HIT DOMAIN CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04438">
        <property type="entry name" value="zf-HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="HIT-type" evidence="5">
        <location>
            <begin position="86"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="139" mass="16142" checksum="7C5139727EFBD9B9" modified="2017-02-15" version="1">MGRKRLEKNIKNVKKRKRKKGSDSEDNDDIEITNNTVSLNRNVSCKFKQREKVDINLILAQDEADAFKMKSYCWTTVSGGSTSLIRRKFCIVCGFEGKYKCLKCYEHKPKSYIRYYCSLNCKKIHDDSSCCKSKMLDIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT68</accession>
    <name>A0A1J1GT68_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fam-j protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00189600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000026">
        <property type="protein sequence ID" value="CRG94499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527317.1">
        <property type="nucleotide sequence ID" value="XM_028670579.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT68"/>
    <dbReference type="GeneID" id="39730421"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00189600"/>
    <dbReference type="OMA" id="MHIANEE"/>
    <dbReference type="OrthoDB" id="10641085at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="5"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="347"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="870" mass="103190" checksum="8E2C05B6E4469DD1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTE3</accession>
    <name>A0A1J1GTE3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00276600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528377.1">
        <property type="nucleotide sequence ID" value="XM_028671757.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTE3"/>
    <dbReference type="GeneID" id="39731299"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00276600"/>
    <dbReference type="OMA" id="NIEKFGH"/>
    <dbReference type="OrthoDB" id="392364at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="785" mass="94125" checksum="D323ED54AA131D3C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTP3</accession>
    <name>A0A1J1GTP3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00280800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528419.1">
        <property type="nucleotide sequence ID" value="XM_028671803.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTP3"/>
    <dbReference type="GeneID" id="39731341"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00280800"/>
    <dbReference type="OMA" id="EKYSCAV"/>
    <dbReference type="OrthoDB" id="383419at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="195" mass="22756" checksum="0A36478FB9775186" modified="2017-02-15" version="1">MQNFSYNDLIANIYHVNLYNQRSVIHTEKITKLYNLKNYNSLNKIYLISCGNNFIFKNNKSFNSINNIQNENNIKEDDSDNEDDDKLVLNADSDDNEGNESIEEKKINSDKNIYDNKSTSTNLNYNLEAKNIPTQYKKRSKYDSDKIIIYEDITELPRDICNLLLTDDEIEQINTGVPDCDFGNYVNNITHNKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTR4</accession>
    <name>A0A1J1GTR4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Rab GTPase activator and protein kinase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00182700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527256.1">
        <property type="nucleotide sequence ID" value="XM_028670511.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730354"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00182700"/>
    <dbReference type="OMA" id="WIRYYVH"/>
    <dbReference type="OrthoDB" id="1668230at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="287"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="450"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1105"/>
            <end position="1123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1144"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1203"/>
            <end position="1222"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="808"/>
            <end position="835"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1641" mass="199229" checksum="719B1F33813D5D92" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTS3</accession>
    <name>A0A1J1GTS3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">50S ribosomal protein L1, apicoplast, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00312100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528716.1">
        <property type="nucleotide sequence ID" value="XM_028672133.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTS3"/>
    <dbReference type="GeneID" id="39731654"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00312100"/>
    <dbReference type="OMA" id="DNLEFFH"/>
    <dbReference type="OrthoDB" id="1747252at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_uL1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_uL1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36427">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN L1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36427:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL1M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="Ribosomal protein L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="326" mass="38528" checksum="0B61ABE903367EF1" modified="2017-02-15" version="1">MTKKNGYKIIIEFLFIYTIAFNFICESFLLKSIYFNEVLKKYNFSNTRKALKKKFSQIKNVPSTLITTDEANTNVIKKAKLKKKEKKILKKYKDYLDIIPNRSKEYEIVDALEKIKILAVHKFVESIDVYLSFSQKRSKMTKNDNIKTFITFPHNLKKKREKKIYVVTNRNMHKVACESGADIVGEDDVINKIKEKEIRLKKKNNNFLLSTNDVIHKLTRVGKEIGRKGLMPNEKCGTLVSEFLLSKHIKLFKFQNTYIFKLNKLNTLNLNVGDVYMSNDEIRENICYLFEYLDNLEFFHFNFKNLKTIYLCSTMGFPFKIKKNFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU14</accession>
    <name>A0A1J1GU14_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">U5 small nuclear ribonucleoprotein 200 kDa helicase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">BRR2</name>
        <name evidence="11" type="ORF">PGAL8A_00192700</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. SKI2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000029">
        <property type="protein sequence ID" value="CRG94529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527344.1">
        <property type="nucleotide sequence ID" value="XM_028670608.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730452"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00192700"/>
    <dbReference type="OMA" id="WISCETE"/>
    <dbReference type="OrthoDB" id="5575at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:003287">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein 200 kDa helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000012">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000024">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000004">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3380.10:FF:000001">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000062">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.10">
        <property type="entry name" value="Sec63 N-terminal domain-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041094">
        <property type="entry name" value="Brr2_helicase_PWI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048863">
        <property type="entry name" value="BRR2_plug"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050474">
        <property type="entry name" value="Hel308_SKI2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004179">
        <property type="entry name" value="Sec63-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057842">
        <property type="entry name" value="WH_MER3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961:SF4">
        <property type="entry name" value="ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961">
        <property type="entry name" value="DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21188">
        <property type="entry name" value="BRR2_plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18149">
        <property type="entry name" value="Helicase_PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02889">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23445">
        <property type="entry name" value="WHD_SNRNP200"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00973">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158702">
        <property type="entry name" value="Sec63 N-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="717"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="941"/>
            <end position="1158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="222"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="507"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="227"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="274"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="288"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="304"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="507"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="541"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="585"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00034541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG94529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2625" mass="310798" checksum="DB6D72881172F880" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU20</accession>
    <name>A0A1J1GU20_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00322500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000049">
        <property type="protein sequence ID" value="CRG96012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528820.1">
        <property type="nucleotide sequence ID" value="XM_028672249.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU20"/>
    <dbReference type="GeneID" id="39731758"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00322500"/>
    <dbReference type="OMA" id="SSYQIIC"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="405"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="448" mass="53801" checksum="789912A28101A61A" modified="2017-02-15" version="1">MKTLTLYLKFTTFLLLIWMYQYFYNCDSYKTLIDKNILQIKNELKYERVLTEVDIAGEKQTNAEGCQEECPTENKEKEKKKKIWKNSRKLSNPYDLWQKFTNPLLSERFKNEISGMDPKRIDEKWKNEWNQISENKVKDLSSIFQRSDISNEEKEKLILDTKTELFKLYMDFVDEAKNEVRGNKTESESESEKEMRDNKTKSESIKEMIDNRTETESMNEIRENITESESEKAMRDSKTESESKKEMRENRTESESTKEMRDNKAESESESESESEKEMRDNKTESEFEKVMRENKRESESESEKKMRGNKTESESKYEKEMRDNKTESESIKEMIDNRTETESMKEIRENITESESEKEMRDNETESESESEKEMRDNETESESEYESEKEMRDNETESESESESEKEMRENKTESESRKEQGTYEITNYKKKIWELHIVLIILRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU35</accession>
    <name>A0A1J1GU35_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00325100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000052">
        <property type="protein sequence ID" value="CRG96038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528846.1">
        <property type="nucleotide sequence ID" value="XM_028672278.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU35"/>
    <dbReference type="GeneID" id="39731784"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00325100"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="305"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="337" mass="40151" checksum="BBDB41BD4195CAB9" modified="2017-02-15" version="1">MAFLNNEGCEDSQGDLTKCYMNICEINQKKFETSYCKIDIPVVDIKKTLNNNFNDLSRNLFLHEYNPPNFKNRIIILSNNEKDGILLLYEYNPQYNKYPEKTYLCRLRNIKQKLTLCESINIEYLGRSLTFDSYDIINIENKNNNMISLKNPNHKIIKSKYDDLIFKEHFCHHMKTKYISYCNKRYTICKKINDDKLECSDANYSGHLIKLDYNKNPILIRKHIYLPRSCLKENLNPVCTPYICINSDFDEFFQCEYEEISVIKNIRPIKHIIPIKNIRPNSKNLPVISLKHKDISDKNSFDNTALFAMSFMSFLVIFTFFFCLLYKIFRKKRRKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU90</accession>
    <name>A0A1J1GU90_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00326400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000053">
        <property type="protein sequence ID" value="CRG96050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528858.1">
        <property type="nucleotide sequence ID" value="XM_028672291.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU90"/>
    <dbReference type="GeneID" id="39731796"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00326400"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012181804" evidence="2">
        <location>
            <begin position="23"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="458" mass="54367" checksum="1BE0DC05EF0484BE" modified="2017-02-15" version="1">MKSLILYLKITTFLLLIWMYQCFYNCDSYKSLIDKNILQTKNKLKYERVLTEGDIAGKMQTYSEGCLEECSLDNKKNKWENPIQNENPRDRWQRKTNPLFRKIFDKKTSEMDPKWRDQKWNNEWNKISANKVNELSSIFHRSDISEEEKKELIRNVKDELDMEFWTFLDKCKKEMTDNKSESESMKEMTDNKTECESKKEMTDNITESESIKEMRDDKTESESMKGMIDNKTESEYKLEMRDNKTESESSKVMRGNKTESESNNEIRDNKTESESRNEMTDNKTESESNKEMIDNKTESESMNEMTDNKTESESKNEMTDNKNESESIKGMIENKTESEFKIEMADNKSEFESMKEMIDNKTESESMKRMTDNKTESESMKMMIDNKTESESKIEMTDNKTESESRIEMTDNKTESESKKDMIDNKTQSESKNEKGKNKIKNKKSNILKFLFKRFDNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUN9</accession>
    <name>A0A1J1GUN9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SCD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00215800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527576.1">
        <property type="nucleotide sequence ID" value="XM_028670867.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730685"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00215800"/>
    <dbReference type="OMA" id="QMSKMKI"/>
    <dbReference type="OrthoDB" id="498590at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020839">
        <property type="entry name" value="SCD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013721">
        <property type="entry name" value="STAG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35711:SF1">
        <property type="entry name" value="ECTODERMAL, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35711">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21581">
        <property type="entry name" value="SCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08514">
        <property type="entry name" value="STAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51425">
        <property type="entry name" value="SCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCD" evidence="3">
        <location>
            <begin position="547"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="25"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="180"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="677"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="874"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1276"/>
            <end position="1336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1473"/>
            <end position="1520"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2022"/>
            <end position="2056"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="27"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="83"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="107"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="193"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="677"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="884"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="922"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1287"/>
            <end position="1319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1326"/>
            <end position="1336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1473"/>
            <end position="1503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1504"/>
            <end position="1520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2224" mass="264034" checksum="661FBEBBF9873CCC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUP5</accession>
    <name>A0A1J1GUP5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter F family member 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">GCN20</name>
        <name evidence="5" type="ORF">PGAL8A_00348300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529070.1">
        <property type="nucleotide sequence ID" value="XM_028672526.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUP5"/>
    <dbReference type="GeneID" id="39732013"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00348300"/>
    <dbReference type="OMA" id="CTHIADI"/>
    <dbReference type="OrthoDB" id="2110130at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF117">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="181"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="572"/>
            <end position="788"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="788" mass="92070" checksum="C7E8BD1794FB34E9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUV2</accession>
    <name>A0A1J1GUV2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-i protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00323200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000050">
        <property type="protein sequence ID" value="CRG96019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528827.1">
        <property type="nucleotide sequence ID" value="XM_028672257.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUV2"/>
    <dbReference type="GeneID" id="39731765"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00323200"/>
    <dbReference type="OMA" id="TSWAQQC"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="397"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="481" mass="58715" checksum="4210D80669267CA7" modified="2017-02-15" version="1">MDLNLSDAIGIDSSKRLNEGDSTAGFAHRVIKDATVSIPKNPLYDDSNLRSAIQNPSEDIKLDSAKSVNVLHKKSLSFFQLVMIFIYFLRFARAHSPNLKAKHKERVRLQNKWDNRDKKMKGDREKMEKKWDERKQKENREKEELKKKEEERKKKTNNEMKEFNMKWNGEKERENDSEDKSLQILNSLRASGKNIESLNKPSTSQACNKTVKKKENNNMPSDNKGEKLKEKSSNKLNSELEREKKRIETFYRQMFQLDEKWKKYEEDCIMMNERKKEERKKLEEIRRERKKKHEQEMLKENEEWKKSMIEKNKEWKMSMIKKNKEWEKRMQKEKEGGENGVLKEMEELEKRRLKEMEELEKRRLKVIERLEKIVLEKKEELDKKMIKKKEGLEKKLLKEKKEKKEKEEGEDRMQKEKEEWEKEMQKEKEEWEKGMQKEKEEWKKNIKEKNEKWEREENMKVNEEESEFNLKWKKELDKIKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUZ3</accession>
    <name>A0A1J1GUZ3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">60S ribosomal protein L18-2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00252400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527933.1">
        <property type="nucleotide sequence ID" value="XM_028671263.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUZ3"/>
    <dbReference type="GeneID" id="39731052"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00252400"/>
    <dbReference type="OMA" id="IDICHKN"/>
    <dbReference type="OrthoDB" id="6353017at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.100.10.10:FF:000001">
        <property type="entry name" value="60S ribosomal protein L18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.100.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000039">
        <property type="entry name" value="Ribosomal_eL18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021132">
        <property type="entry name" value="Ribosomal_eL18/eL18-A/B/_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_uL15/eL18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="Ribosomal_uL15/eL18_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10934">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10934:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17135">
        <property type="entry name" value="Ribosomal_L18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="Ribosomal proteins L15p and L18e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01106">
        <property type="entry name" value="RIBOSOMAL_L18E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL15/eL18" evidence="5">
        <location>
            <begin position="2"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="147"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="160"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="177"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="187" mass="21422" checksum="A37C8F9BDEFB1238" modified="2017-02-15" version="1">MGIALKNVGRIKKHGRKYLVSKNPYMRLLVKLYKFLARRTNANFNKIIAKRLIMPKRFRPPLSLSKLQAHMMRHPDNVAVVVGSITDDKRLFSCKKLKVCALRFTETARKRILDAGGECLTFDQLALKYPTGKRCILLRGPTKARTAEKHFGKAPGVPKSKARPYVRSKGRKFEKARGRRKSRAYKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV18</accession>
    <name>A0A1J1GV18_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Multiprotein bridging factor type 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">MBF1</name>
        <name evidence="5" type="ORF">PGAL8A_00355100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529138.1">
        <property type="nucleotide sequence ID" value="XM_028672602.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV18"/>
    <dbReference type="GeneID" id="39732081"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00355100"/>
    <dbReference type="OMA" id="KANQQRS"/>
    <dbReference type="OrthoDB" id="10253401at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.260.40:FF:000018">
        <property type="entry name" value="Multiprotein bridging factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="entry name" value="lambda repressor-like DNA-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013729">
        <property type="entry name" value="MBF1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10245:SF15">
        <property type="entry name" value="ENDOTHELIAL DIFFERENTIATION-RELATED FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10245">
        <property type="entry name" value="ENDOTHELIAL DIFFERENTIATION-RELATED FACTOR 1 MULTIPROTEIN BRIDGING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08523">
        <property type="entry name" value="MBF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="lambda repressor-like DNA-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="4">
        <location>
            <begin position="79"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="136" mass="15646" checksum="1532F81AB6FE37D4" modified="2017-02-15" version="1">MDHQDIKPVIWHKTEKKTKPKNIEEARKLGIDVEIEKKYFGGKNKSSKGNLIIENKAKIEQENENFKIDRVTPTFSRALQQARMNKKLTQAQLARLINESETVIKEYENGKAIPNNVIIQKLNKVLGVNLPSPKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV26</accession>
    <name>A0A1J1GV26_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Parasitophorous vacuolar protein 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PV1</name>
        <name evidence="3" type="ORF">PGAL8A_00355900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529146.1">
        <property type="nucleotide sequence ID" value="XM_028672611.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV26"/>
    <dbReference type="GeneID" id="39732089"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00355900"/>
    <dbReference type="OMA" id="GICMKFF"/>
    <dbReference type="OrthoDB" id="392929at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013198754" evidence="2">
        <location>
            <begin position="17"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="363"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="391" mass="44167" checksum="11B1666E97689B3D" modified="2017-02-15" version="1">MIKAVLTLLFISYSYAVNVVDSQAKEQIKFSAKLELENPNHVPFLEIINSEFSKVKDFSPDLVKNGYTCSFNKFDIIIHNSSEAINKLFVVGNENYVRWAADEYKLRLMLTLDHLSSTTSLKNLEYNSQNVTSRYFSDLRRYFFELNNENSSDEGEPNDISDEEEVNQVASNYDSNEESKEVNSDLSEVENKEESGETLNNSLQKVSYTYQSSQIVSYNNMNMSNQTEGFSIDEPLTKQNALNILILNSTFSVEGECIKGEEKKENDLCIRFRSKLGTNILSTLCESSGKNFLRKFNGGNNNILLNNESLNEMMGGMYKLIESIFGNDKMFSPFLKDLNVLSNSGQLGFNMDEIVGQALNGNLGDEESETVNEENSSSNNDGNDENTEVQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV43</accession>
    <name>A0A1J1GV43_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nuclear import protein MOG1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00257300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MOG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527981.1">
        <property type="nucleotide sequence ID" value="XM_028671317.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV43"/>
    <dbReference type="GeneID" id="39731101"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00257300"/>
    <dbReference type="OMA" id="EVYVHKF"/>
    <dbReference type="OrthoDB" id="10255285at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1000.10">
        <property type="entry name" value="Mog1/PsbP, alpha/beta/alpha sandwich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007681">
        <property type="entry name" value="Mog1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016123">
        <property type="entry name" value="Mog1/PsbP_a/b/a-sand"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15837">
        <property type="entry name" value="RAN GUANINE NUCLEOTIDE RELEASE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15837:SF0">
        <property type="entry name" value="RAN GUANINE NUCLEOTIDE RELEASE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04603">
        <property type="entry name" value="Mog1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55724">
        <property type="entry name" value="Mog1p/PsbP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="168" mass="20210" checksum="6D973F2962B7A247" modified="2017-02-15" version="1">MEEKLCEYHFFNKYIKMVIPDNYLDVSKFRLIPDNQEVYVHKFDNKCIIIEILCYQNIDDNEKGSFYFYDLAKENDSIENIIIMNNSTIPHSQKNYFLVVGKQKVKKQDSQVYENILLYICIFPFKEYNADILITWNIPKEDLNIQPELNIFNEMIQSFRILDYGLFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV44</accession>
    <name>A0A1J1GV44_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">WD repeat-containing protein WRAP73</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00332500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528915.1">
        <property type="nucleotide sequence ID" value="XM_028672354.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV44"/>
    <dbReference type="GeneID" id="39731855"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00332500"/>
    <dbReference type="OMA" id="CWHLNGD"/>
    <dbReference type="OrthoDB" id="308690at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990811">
        <property type="term" value="C:MWP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052778">
        <property type="entry name" value="Centrosome-WD_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16220">
        <property type="entry name" value="WD REPEAT PROTEIN 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16220:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN WRAP73"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="458" mass="53313" checksum="A7677CAF5CE165C2" modified="2017-02-15" version="1">MKLSHVIKCDKCYFSKDGLFLLHIVENKIFLTELNTFEICRIYVSSYKIDNVDFSNDNIHFLALIKNKGCVYIYSLYKENIIKKIEDFCQTYLDSIFLYKDSNICVYKYEKKCFSIYDINNVEESLVNIENAKFKKSGYCSNDEGSIFACITQNNNKIEISLISLLNYNVINNISCNNLNPNKIFFTKENNIIAFNNKKKSLHMYKTNGELLFIYTYKCELPCINVVAKNEIKNILSVGFENGVVKILSLRDFKEIETLLLDDIIIMNQKLKIYKENISNKDTLSSILSKESNISSHQNNKEKFAYYSNKGIKEGEYKLKHGKEKSNEYVKKNFYNKISKIGITALSFSICGNYLAVINENHSNVVRIYEMENHSCIAILEQKKLVTSMYWDNILYKARLLICTNTSHLFVWLPDECAVLDMPRGFICRDAKWNCYGTVLLAKNDEKLMVFCPKENYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV45</accession>
    <name>A0A1J1GV45_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">CLPTM1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00365000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CLPTM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529230.1">
        <property type="nucleotide sequence ID" value="XM_028672704.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV45"/>
    <dbReference type="GeneID" id="39732180"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00365000"/>
    <dbReference type="OMA" id="SFMYYMF"/>
    <dbReference type="OrthoDB" id="378564at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008429">
        <property type="entry name" value="CLPTM1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21347">
        <property type="entry name" value="CLEFT LIP AND PALATE ASSOCIATED TRANSMEMBRANE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21347:SF0">
        <property type="entry name" value="LIPID SCRAMBLASE CLPTM1L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05602">
        <property type="entry name" value="CLPTM1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="372"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="405"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="488"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="516"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="612"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="615"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="646" mass="76989" checksum="478614914B42F407" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV70</accession>
    <name>A0A1J1GV70_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">lactoylglutathione lyase</fullName>
            <ecNumber evidence="4">4.4.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Aldoketomutase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Ketone-aldehyde mutase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Methylglyoxalase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">S-D-lactoylglutathione methylglyoxal lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00340600</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Secondary metabolite metabolism; methylglyoxal degradation; (R)-lactate from methylglyoxal: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glyoxalase I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.5" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528993.1">
        <property type="nucleotide sequence ID" value="XM_028672441.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV70"/>
    <dbReference type="GeneID" id="39731936"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00340600"/>
    <dbReference type="OMA" id="KTSWEPV"/>
    <dbReference type="OrthoDB" id="16820at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004462">
        <property type="term" value="F:lactoylglutathione lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07233">
        <property type="entry name" value="GlxI_Zn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004361">
        <property type="entry name" value="Glyoxalase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018146">
        <property type="entry name" value="Glyoxalase_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00068">
        <property type="entry name" value="glyox_I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10374:SF30">
        <property type="entry name" value="LACTOYLGLUTATHIONE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10374">
        <property type="entry name" value="LACTOYLGLUTATHIONE LYASE GLYOXALASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00935">
        <property type="entry name" value="GLYOXALASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="VOC" evidence="12">
        <location>
            <begin position="15"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="VOC" evidence="12">
        <location>
            <begin position="179"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG96188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="349" mass="41661" checksum="1383A1768094F14B" modified="2017-02-15" version="1">MKGKMLNFGKKYNITWHQTMLRIYNPKETVEFYEKNFGMINIHTYHFNEQNFSLYFMITPPYDEEEKKKIPKKNTRESEKYLWNLNTVCLELTHNHNSEEKLSNGNNEDDRGFGHIAFNCHDVVELCDELLKKNVKFHKLPHETKMKTIGFALDPNNYWIEIVKRSSEVKWKNKKEITNFSQTMIRIKNPEKSLYFYINILDMKLVHIKHNDDFSLYFLKSTYLNEKDTNNTEEGGLYDFNSLRNSYQSNETYENFKKSWHPVLELTHNHGTEDDDKFSYHNGNTTPRGFGHIGFLVDNLEDYCKELESLNIPFKKKVNEGIMKNIAFIYDPDNYIIELIQRDTTFNVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV72</accession>
    <name>A0A1J1GV72_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Apical exonemal protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00364800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529228.1">
        <property type="nucleotide sequence ID" value="XM_028672702.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV72"/>
    <dbReference type="GeneID" id="39732178"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00364800"/>
    <dbReference type="OrthoDB" id="364460at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="223"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="370"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="426" mass="51615" checksum="83262F07C6D16143" modified="2017-02-15" version="1">MEKLYNCEILDKNINYNNIEKSLIKKNKNFIYDSSASLLDELYFDYYKDGINYTELYKKFKEDNCVKSYNRLPVCAYKYPQNTKIGKFDKLKRELIYDKINNESGEKKNKVDYYNSDLKIFVPNKLKNDNGKKEKKSLRKKIYDGEVMFYEDYLEQVAARDYQYFFKKPYKIKRKDEGGKYYFYGRKIEMNEDEDLYRKYYGYDDEYFLKKMQLNEKSKKKVGNNLKKKKEKEEESLEKEYEKLNHKDKNFILKIKEENEIKNLNIYNFYTKNKNIIFDKNLSEIKKKELLNGYIPDIIFPVNNRKTKHPKNCTVLFSRLNTYAKFLEDLLICPYIHNAIDAELGKYWKTNENDNIKKLKTEKIKKGYKKDIYSVTKEQLEKSNEKLKNLLEKEKENDKNLKVSLNFKIQKEERESKSICNGRYMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVF2</accession>
    <name>A0A1J1GVF2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tubulin--tyrosine ligase, putative</fullName>
            <ecNumber evidence="5">6.3.2.25</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00374600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.25" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529326.1">
        <property type="nucleotide sequence ID" value="XM_028672811.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732276"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00374600"/>
    <dbReference type="OMA" id="KNSHENH"/>
    <dbReference type="OrthoDB" id="202825at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070740">
        <property type="term" value="F:tubulin-glutamic acid ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004835">
        <property type="term" value="F:tubulin-tyrosine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004344">
        <property type="entry name" value="TTL/TTLL_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12241">
        <property type="entry name" value="TUBULIN POLYGLUTAMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12241:SF154">
        <property type="entry name" value="TUBULIN POLYGLUTAMYLASE TTLL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51221">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="984"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1355"/>
            <end position="1396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2508"/>
            <end position="2533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2668"/>
            <end position="2707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1360"/>
            <end position="1369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1373"/>
            <end position="1394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="2519"/>
            <end position="2533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="2672"/>
            <end position="2707"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2786" mass="330361" checksum="A8E5AA24051459ED" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVG0</accession>
    <name>A0A1J1GVG0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">U6 snRNA-associated Sm-like protein LSm1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">LSM1</name>
        <name evidence="6" type="ORF">PGAL8A_00351000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Probably involved with other LSm subunits in the general process of degradation of mRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">LSm subunits form a heteromer with a donut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
            <location evidence="4">P-body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVG0"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00351000"/>
    <dbReference type="OMA" id="EQSMPLW"/>
    <dbReference type="OrthoDB" id="422364at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990726">
        <property type="term" value="C:Lsm1-7-Pat1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01728">
        <property type="entry name" value="LSm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034104">
        <property type="entry name" value="Lsm1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044642">
        <property type="entry name" value="PTHR15588"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588">
        <property type="entry name" value="LSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588:SF8">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Sm" evidence="5">
        <location>
            <begin position="10"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU365047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="146" mass="17097" checksum="ADBE6A2B74470655" modified="2017-02-15" version="1">MEQSMPLWLSSFEEEIDTYIFISSRDNKLYLGILRTYDQHGNIFLTHCVEKIIVAEKNCFSDVYVGNLIIRGDNIAYFGSVDEEKYSKIFDYSQKNTKENYLDNEGINIPNEKNNSSENMILQYKPVNYILKFISENNNDSSIFEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVH0</accession>
    <name>A0A1J1GVH0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00411900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000061">
        <property type="protein sequence ID" value="CRG96537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529342.1">
        <property type="nucleotide sequence ID" value="XM_028672828.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVH0"/>
    <dbReference type="GeneID" id="39732649"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00411900"/>
    <dbReference type="OMA" id="IDKKMNQ"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="27"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="78" mass="9475" checksum="88E27CB378992FB0" modified="2017-02-15" version="1">MDNKESLFYNGVIDPYVVNYIWLYGKKENSMEKNNENKIELNNENNKNDNIKDKSYIDKKMNQIHKLNNNEKREDILY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVR3</accession>
    <name>A0A1J1GVR3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter B family member 5, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ABCB5</name>
        <name evidence="10" type="ORF">PGAL8A_00250900</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527920.1">
        <property type="nucleotide sequence ID" value="XM_028671249.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVR3"/>
    <dbReference type="GeneID" id="39731037"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00250900"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF1">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="314"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="349"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="73"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="455"/>
            <end position="835"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG95107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="839" mass="98002" checksum="D832147322F71806" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVS6</accession>
    <name>A0A1J1GVS6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Phosphatidylinositol N-acetylglucosaminyltransferase, putative</fullName>
            <ecNumber evidence="9">3.5.1.89</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00423800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PIGC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.89" evidence="9"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529462.1">
        <property type="nucleotide sequence ID" value="XM_028672961.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVS6"/>
    <dbReference type="GeneID" id="39732770"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00423800"/>
    <dbReference type="OMA" id="QIFVLWL"/>
    <dbReference type="OrthoDB" id="417678at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000506">
        <property type="term" value="C:glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000225">
        <property type="term" value="F:N-acetylglucosaminylphosphatidylinositol deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009450">
        <property type="entry name" value="Plno_GlcNAc_GPI2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12982">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL GLYCAN, CLASS C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12982:SF0">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06432">
        <property type="entry name" value="GPI2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016104">
        <property type="entry name" value="GPI2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="230"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG96658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="306" mass="35735" checksum="8B9842A0A668BFD5" modified="2017-02-15" version="1">MDHTNNALPKEEIKKKKKWRKILYEDLGYDDNYVDNSFLSSLLTNFGIKYKYSYVCLRMLCVNHQLMLVLFFLLSYYYIDKNIITYKFVTLISSITIILKEILIYETHRSLNSSLKNILDTIIIIGIIWILSPVLITLTQTHSDDTVYLVSILLLLFHLMFHNYGFIYEKNENINIFDATSLSCVVIASVILGSRLSSILQVFSFLFLSSILFFYSPFIFQTIALKNICYYNYILFPILFLILSFSIRRISITFFYLNLIGHIFVLLIVPAFFIEKNTLKTKLEGPWDIAVSLQDSTGINKKIKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVY8</accession>
    <name>A0A1J1GVY8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00266100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000035">
        <property type="protein sequence ID" value="CRG95458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528269.1">
        <property type="nucleotide sequence ID" value="XM_028671636.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVY8"/>
    <dbReference type="GeneID" id="39731190"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00266100"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="110" mass="12534" checksum="B8FD63BCB89C831A" modified="2017-02-15" version="1">MDGKSNSSAGNSINPLMSNCQTYEMAMYIAVILVAFTVILSLICMLYQASSLKKELKEYNMWYRKFDEHLRSKNGDGIEATDSVYIVNSEKELLLGRNNKCEDSEDEFNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVZ3</accession>
    <name>A0A1J1GVZ3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Pre-mRNA-splicing factor SLU7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00259200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in pre-mRNA splicing.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the SLU7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528000.1">
        <property type="nucleotide sequence ID" value="XM_028671338.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVZ3"/>
    <dbReference type="GeneID" id="39731121"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00259200"/>
    <dbReference type="OMA" id="WQNQEKI"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030628">
        <property type="term" value="F:pre-mRNA 3'-splice site binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019339">
        <property type="entry name" value="CIR_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039974">
        <property type="entry name" value="Splicing_factor_SLU7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12942:SF2">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR SLU7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12942">
        <property type="entry name" value="STEP II SPLICING FACTOR SLU7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10197">
        <property type="entry name" value="Cir_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01083">
        <property type="entry name" value="Cir_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5 7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="CBF1-interacting co-repressor CIR N-terminal" evidence="9">
        <location>
            <begin position="18"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="24"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG95188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="210" mass="25307" checksum="737EE045442E7B9A" modified="2017-02-15" version="1">MWINKIGNKSASFINHKHFHPGNIKNLERVWIAEENERKRKEEEEKYLKKREEQYKIYILKKQLRKNEEENKNYLNNIIYDVNKESKTDKIKIHTTANINKKNENNKNNINENMKHKLTIKSKYNEDIFLKNHKSIYGSYYDRDKKKWGYKCCKNIDKNSSCINNICDHVKINNQNVHVKKDLKKKKKKKKKKKDIVDNSITAVLNKISI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW34</accession>
    <name>A0A1J1GW34_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00434400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529566.1">
        <property type="nucleotide sequence ID" value="XM_028673077.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW34"/>
    <dbReference type="GeneID" id="39732876"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00434400"/>
    <dbReference type="OrthoDB" id="371704at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="397" mass="49398" checksum="0736EF07BE625E9B" modified="2017-02-15" version="1">MIKIYKEYFNGRYYFSNIFSYIILYLHNKENFFKKRTNKNKLCDNYKKSFSLKKKVINDKKKKNIVIHFPSEEISHFYFHYFVYILIPKLNLSEYDKKKIIDNIYLINNKIDENVKTYIFNKVNQSNCNIIFCNKLLPKEKYNYSGTLLMFLENKYFLDFFLKLHKKKKKKKKHLFLKRKEKNFNRINNNFYNLKKNREDTICNYLYMFYLLNYNFKKQIIIKRNKNLELLTKYNQKIKEINNNIQWFNHYSFYKFYYNAYISFLNYRMLIFQSLMENVMKKKKKNALYIFLKYKNLTLNSNIFFDFINKQILYVNFNDAATLYIKFLQLFEKIALFSNIKNYSNYNISNINEKRKYNKNILIKEIKKNMNIHIWNNYENENFHSNLNKIKLYRFYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW85</accession>
    <name>A0A1J1GW85_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00438200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PPP phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529604.1">
        <property type="nucleotide sequence ID" value="XM_028673119.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW85"/>
    <dbReference type="GeneID" id="39732915"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00438200"/>
    <dbReference type="OMA" id="EVKLMCT"/>
    <dbReference type="OrthoDB" id="1930084at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07415">
        <property type="entry name" value="MPP_PP2A_PP4_PP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047129">
        <property type="entry name" value="PPA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45619">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="5">
        <location>
            <begin position="265"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="466" mass="54557" checksum="22A5DE47BDB10519" modified="2017-02-15" version="1">MRNYELSEGDFIFNNIINSNNNLKCLNKNLKKDSKNLEIMKNDDHIDQDNEHLEQKYKISNDDKNTINYQKLISEENYKLYDNLSVKELSDEEVNSENEYNRKIKKNRNSSLNNEKLNEYNENCEKISKEKYKKNPLDNGQIKDNISYNVNMNSSKIMYNVDEWICKLFKCELLNIEEIKLMCELLIDILKDEENCVKVDVPVTVAGDIHGQFYDLLELFHIGGLPPDVNYLFLGDYVDRGYYSCECFCLVACFKIKYPKRVTILRGNHESRQITKVYGFYDECIRKYNNNYNVWKYLTDAFDYLPLTAIINDEIFCDHGGISPYLHTIDEINELDRFKEIPQDGAICDLLWSDPAGPEDEIMEGWKPSPRGAGVLFSEEKTNTFLRMNNLRCICRAHQLVQDGFQWMHNDKVVTVFSAPNYCYRCGNSASLMLVDEFMEKDFVTFNTAPLRANAQALRKNVDYML</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW92</accession>
    <name>A0A1J1GW92_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycolipid transfer protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00428700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529511.1">
        <property type="nucleotide sequence ID" value="XM_028673016.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW92"/>
    <dbReference type="GeneID" id="39732819"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00428700"/>
    <dbReference type="OMA" id="WMKRTIE"/>
    <dbReference type="OrthoDB" id="205255at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902387">
        <property type="term" value="F:ceramide 1-phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902388">
        <property type="term" value="F:ceramide 1-phosphate transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3520.10">
        <property type="entry name" value="Glycolipid transfer protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036497">
        <property type="entry name" value="GLTP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014830">
        <property type="entry name" value="Glycolipid_transfer_prot_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10219">
        <property type="entry name" value="GLYCOLIPID TRANSFER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10219:SF25">
        <property type="entry name" value="PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08718">
        <property type="entry name" value="GLTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110004">
        <property type="entry name" value="Glycolipid transfer protein, GLTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Glycolipid transfer protein" evidence="2">
        <location>
            <begin position="29"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="217" mass="25311" checksum="335590A10B60A7D5" modified="2017-02-15" version="1">MTNILEGKIFLKEIEKKSLECREKDEILVLKLCELSNAIYPIYNKIFGDGFLGETLKKDLKNSSLKVKKAVEKVPEETKYVSKMYSYNLKKYENLEKLKKDMDNGLINFMWMKRALEFIVVFLEKCYVTKSSSKLNICAQEAYEEVLKSYHGYITVNLVKLGIKLSPSRENLTKRLGFESNEEAKIVIQNFILITKPLINDISKIMEKYNCNFKDKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWI0</accession>
    <name>A0A1J1GWI0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Gametocyte development protein 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">GDV1</name>
        <name evidence="1" type="ORF">PGAL8A_00448600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529708.1">
        <property type="nucleotide sequence ID" value="XM_028673235.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWI0"/>
    <dbReference type="GeneID" id="39733019"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00448600"/>
    <dbReference type="OMA" id="CGILLDF"/>
    <dbReference type="OrthoDB" id="391544at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="568" mass="68550" checksum="75265712BF8D36D9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWP6</accession>
    <name>A0A1J1GWP6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein MAK16 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00020600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the MAK16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528248.1">
        <property type="nucleotide sequence ID" value="XM_028671613.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWP6"/>
    <dbReference type="GeneID" id="39728728"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00020600"/>
    <dbReference type="OMA" id="DKGQNFC"/>
    <dbReference type="OrthoDB" id="10251342at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000470">
        <property type="term" value="P:maturation of LSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006958">
        <property type="entry name" value="Mak16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029004">
        <property type="entry name" value="Ribosomal_eL28/Mak16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23405">
        <property type="entry name" value="MAINTENANCE OF KILLER 16 MAK16 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23405:SF4">
        <property type="entry name" value="PROTEIN MAK16 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01778">
        <property type="entry name" value="Ribosomal_L28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003352">
        <property type="entry name" value="MAK16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal eL28/Mak16" evidence="6">
        <location>
            <begin position="6"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="219"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="327"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="233"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR003352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="355" mass="42563" checksum="48811741AE7C88DE" modified="2017-02-15" version="1">MQNDSVTWEILGKGKCSFKKKLETETFCLNEYNVTGLCTKVNCPLSNSVYGTVILDKGKIYLYLKCAEKAHLPNKMWNRILLSLNRKEAFHVIYKEMRYLHNIKQIKKCMKRYVRIKEILKRSRKLILQKQVKLLPIKKKTERRDRTRENKALKAANILNNVEKELLNRLSSGLYGNLYKFLTPKKKIKNKDSELSKIFNEVKEKKTIKKKVIEKETIENENNEFTSQTNFSDENEEEEEDDDEEENYDDDDEENFEDIDYLNDNDEEELSEDFDEEEYLSDDDNYDENNNKKKKKKNYIKEYVDENYIKNLQENGKFPNDDEIEEVNHNFRKKRNTNNNKKKSKKKIRIAYEND</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWU6</accession>
    <name>A0A1J1GWU6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00269600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000039">
        <property type="protein sequence ID" value="CRG95495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528304.1">
        <property type="nucleotide sequence ID" value="XM_028671675.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWU6"/>
    <dbReference type="GeneID" id="39731227"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00269600"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="134" mass="16129" checksum="55BF4E38D4495535" modified="2017-02-15" version="1">MKTFTLYLKIFTFLHLIWIFPFFYKYDSSKSLINRDTLQTKIGLKHERILAEGDISEEKSSYIKNLVEHYPSGEEEMRLYEFVHLMDMYIKCYIANIVSNIVQEVLFKKANEMRYKCRDKILNAYRNNITESLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX15</accession>
    <name>A0A1J1GX15_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidyl-prolyl cis-trans isomerase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00443500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529657.1">
        <property type="nucleotide sequence ID" value="XM_028673178.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX15"/>
    <dbReference type="GeneID" id="39732968"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00443500"/>
    <dbReference type="OrthoDB" id="30774at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016818">
        <property type="entry name" value="NOSIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13063">
        <property type="entry name" value="ENOS INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13063:SF10">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04641">
        <property type="entry name" value="Rtf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="1">
        <location>
            <begin position="324"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="601" mass="71507" checksum="CA16596EC9D33924" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXA0</accession>
    <name>A0A1J1GXA0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">5-formyltetrahydrofolate cyclo-ligase</fullName>
            <ecNumber evidence="5">6.3.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00465700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(6S)-5-formyl-5,6,7,8-tetrahydrofolate + ATP = (6R)-5,10-methenyltetrahydrofolate + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10488"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.3.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.2" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529879.1">
        <property type="nucleotide sequence ID" value="XM_028673426.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXA0"/>
    <dbReference type="GeneID" id="39733190"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00465700"/>
    <dbReference type="OMA" id="NFNMCIY"/>
    <dbReference type="OrthoDB" id="2015992at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030272">
        <property type="term" value="F:5-formyltetrahydrofolate cyclo-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009396">
        <property type="term" value="P:folic acid-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10420">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002698">
        <property type="entry name" value="FTHF_cligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024185">
        <property type="entry name" value="FTHF_cligase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23407:SF1">
        <property type="entry name" value="5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23407">
        <property type="entry name" value="ATPASE INHIBITOR/5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01812">
        <property type="entry name" value="5-FTHF_cyc-lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00036539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="378" mass="45664" checksum="F68EDD3E2A628671" modified="2017-02-15" version="1">MNLESCNKINYLDINDYKKSIINVDLKHYFKNYGYENCKELKEIIRKNAKKIREIIFRNSLIKKNDTCDNTKCTIKNNIYKNKEIINTNNEKNEIFKNKIISKKKSILYKDYLYTLLIRNLYILFSSLNLEKKKEKKFDFTKVYTYEYNYKELTLNKVIDHLKNYGIIDVKLTDIKNFKFFTYCNKLKTNFNDKESNFNICIYIPTKKEVDILFIIEALYDYFYFNLYVPITTKNNDLIFFPFNIINNVLVKHNFNIFVPYLYIYLNTHNKISFNLNNLNIITNKLFNFTYKENDTIFIIPLIAYNNYGCRIGSGKGYYDKTLKKNKNITNLHKKDIKNEIKISVSFEVFLYDIDFYETTDIILDYIINEKNIYHFLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYD8</accession>
    <name>A0A1J1GYD8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Translocation protein SEC63, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00515100</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530379.1">
        <property type="nucleotide sequence ID" value="XM_028673981.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYD8"/>
    <dbReference type="GeneID" id="39733684"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00515100"/>
    <dbReference type="OMA" id="RAILHAH"/>
    <dbReference type="OrthoDB" id="1734229at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031207">
        <property type="term" value="C:Sec62/Sec63 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006620">
        <property type="term" value="P:post-translational protein targeting to endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000077">
        <property type="entry name" value="Translocation protein SEC63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.10">
        <property type="entry name" value="Sec63 N-terminal domain-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004179">
        <property type="entry name" value="Sec63-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24075">
        <property type="entry name" value="SEC63 DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24075:SF0">
        <property type="entry name" value="TRANSLOCATION PROTEIN SEC63 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02889">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00973">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158702">
        <property type="entry name" value="Sec63 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="99"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="219"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="11">
        <location>
            <begin position="129"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="599"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="635"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG97578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="647" mass="75597" checksum="FF5CF7802C54C889" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYM2</accession>
    <name>A0A1J1GYM2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">RNA-splicing ligase RtcB homolog</fullName>
            <ecNumber evidence="10">6.5.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">3'-phosphate/5'-hydroxy nucleic acid ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">RTCB</name>
        <name evidence="14" type="ORF">PGAL8A_00333000</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP + H2O = a ribonucleotidyl-ribonucleotide-RNA + GMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:68080"/>
            <dbReference type="Rhea" id="RHEA-COMP:10464"/>
            <dbReference type="Rhea" id="RHEA-COMP:13936"/>
            <dbReference type="Rhea" id="RHEA-COMP:17355"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:83064"/>
            <dbReference type="ChEBI" id="CHEBI:138284"/>
            <dbReference type="ChEBI" id="CHEBI:173118"/>
            <dbReference type="EC" id="6.5.1.8"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 10">
            <text>a 3'-end 3'-phospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP = a ribonucleotidyl-ribonucleotide-RNA + GMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:68076"/>
            <dbReference type="Rhea" id="RHEA-COMP:10463"/>
            <dbReference type="Rhea" id="RHEA-COMP:13936"/>
            <dbReference type="Rhea" id="RHEA-COMP:17355"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:83062"/>
            <dbReference type="ChEBI" id="CHEBI:138284"/>
            <dbReference type="ChEBI" id="CHEBI:173118"/>
            <dbReference type="EC" id="6.5.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 13">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="10 13">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Catalytic component of the tRNA-splicing ligase complex.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="10">Ligation probably proceeds through 3 nucleotidyl transfer steps, with 2',3'-cyclic phosphate termini being hydrolyzed to 3'-P termini in a step that precedes 3'-P activation with GMP. In the first nucleotidyl transfer step, RTCB reacts with GTP to form a covalent RTCB-histidine-GMP intermediate with release of PPi; in the second step, the GMP moiety is transferred to the RNA 3'-P; in the third step, the 5'-OH from the opposite RNA strand attacks the activated 3'-P to form a 3',5'-phosphodiester bond and release GMP.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the RtcB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.8" evidence="10"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528920.1">
        <property type="nucleotide sequence ID" value="XM_028672360.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYM2"/>
    <dbReference type="GeneID" id="39731860"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00333000"/>
    <dbReference type="OMA" id="QTRGVEC"/>
    <dbReference type="OrthoDB" id="10249697at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072669">
        <property type="term" value="C:tRNA-splicing ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003972">
        <property type="term" value="F:RNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0170057">
        <property type="term" value="F:RNA ligase (GTP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006388">
        <property type="term" value="P:tRNA splicing, via endonucleolytic cleavage and ligation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="entry name" value="tRNA-splicing ligase RtcB homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1860.10">
        <property type="entry name" value="tRNA-splicing ligase RtcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03144">
        <property type="entry name" value="RtcB_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001233">
        <property type="entry name" value="RtcB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036025">
        <property type="entry name" value="RtcB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027513">
        <property type="entry name" value="RtcB_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11118">
        <property type="entry name" value="RNA-SPLICING LIGASE RTCB HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11118:SF1">
        <property type="entry name" value="RNA-SPLICING LIGASE RTCB HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01139">
        <property type="entry name" value="RtcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103365">
        <property type="entry name" value="Hypothetical protein PH1602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10 12" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 10 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 10 13" id="KW-0464">Manganese</keyword>
    <keyword evidence="4 10 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0819">tRNA processing</keyword>
    <feature type="active site" description="GMP-histidine intermediate" evidence="10 11">
        <location>
            <position position="430"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 12">
        <location>
            <begin position="228"/>
            <end position="232"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 12">
        <location>
            <begin position="355"/>
            <end position="356"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="355"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 12">
        <location>
            <begin position="404"/>
            <end position="407"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 12">
        <location>
            <position position="411"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 12">
        <location>
            <begin position="430"/>
            <end position="433"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
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        <location>
            <position position="506"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00008071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00023211"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00047746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG96115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="507" mass="56680" checksum="8C3C97534D469D47" modified="2017-02-15" version="1">MKSQKRGDNVFSYIEKTKEKNLYKINKGLVQNMNVEGHIYVNERLKLLIDDEIKTYEQNRCSTFLPAVMQIANVSTLPGIVKASIALPDVHAGYGFSIGNVAAFDMNKEEAIVSPGGVGFDINCGVRLIRTNLFYDDIKPKQEELTQSLFNHIPVGVGSQGFILCNQENLDDALCLGMDWCVREGYSWIEDKLNCEDNGRSLYADSNYVSVRAKKRGITQMGTLGAGNHYAEIQIVDEIYDKRSAKLMGIEKKNQVCIMIHSGSRGLGHQIATDALIEMEKSMNKYKINVIDKQLACTPIYSKEGQNYLKAMGSACNFAWINRSSMTFLARQTFSKMFNQSPDDLDMHVIYDVSHNIAKIEEHFVDGKVKNLLVHRKGSTRAFPPFHPLVPLDYQYCGQPILIGGTMGTYSYVLTGTEKAMQATFGSTCHGAGRALSRNKSRNTLNYIDVLNKLKEENISIRVASPKLIMEEAPESYKNVSEVVQTCHDAGISNKCFRLKPIAVIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYW2</accession>
    <name>A0A1J1GYW2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00522900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530454.1">
        <property type="nucleotide sequence ID" value="XM_028674063.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYW2"/>
    <dbReference type="GeneID" id="39733762"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00522900"/>
    <dbReference type="OMA" id="NGMVYDD"/>
    <dbReference type="OrthoDB" id="386891at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="395"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="519"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="551"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="83"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="329"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="562"/>
            <end position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="585" mass="68058" checksum="3E7F08FDEB20C005" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ08</accession>
    <name>A0A1J1GZ08_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RuvB-like helicase</fullName>
            <ecNumber evidence="8">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00526400</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the RuvB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530489.1">
        <property type="nucleotide sequence ID" value="XM_028674103.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ08"/>
    <dbReference type="GeneID" id="39733797"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00526400"/>
    <dbReference type="OMA" id="VIIRTHT"/>
    <dbReference type="OrthoDB" id="10060499at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000010">
        <property type="entry name" value="RuvB-like helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.360:FF:000001">
        <property type="entry name" value="RuvB-like helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.360">
        <property type="entry name" value="RuvB-like helicase, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027238">
        <property type="entry name" value="RuvB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041048">
        <property type="entry name" value="RuvB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042487">
        <property type="entry name" value="RuvBL1/2_DNA/RNA_bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010339">
        <property type="entry name" value="TIP49_P-loop"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11093">
        <property type="entry name" value="RUVB-RELATED REPTIN AND PONTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06068">
        <property type="entry name" value="TIP49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17856">
        <property type="entry name" value="TIP49_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="9">
        <location>
            <begin position="126"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG97688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="514" mass="59312" checksum="599C2FCF97EFC004" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZB0</accession>
    <name>A0A1J1GZB0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00521500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530440.1">
        <property type="nucleotide sequence ID" value="XM_028674048.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZB0"/>
    <dbReference type="GeneID" id="39733748"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00521500"/>
    <dbReference type="OrthoDB" id="372484at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="573"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="592"/>
            <end position="606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="629" mass="74151" checksum="07F159672374D10C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZE1</accession>
    <name>A0A1J1GZE1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">GTPase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00523900</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530464.1">
        <property type="nucleotide sequence ID" value="XM_028674074.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZE1"/>
    <dbReference type="GeneID" id="39733772"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00523900"/>
    <dbReference type="OMA" id="CFIHIKS"/>
    <dbReference type="OrthoDB" id="391988at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030393">
        <property type="entry name" value="G_ENGB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11649:SF13">
        <property type="entry name" value="ENGB-TYPE G DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11649">
        <property type="entry name" value="MSS1/TRME-RELATED GTP-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51706">
        <property type="entry name" value="G_ENGB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="EngB-type G" evidence="6">
        <location>
            <begin position="102"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="287" mass="34007" checksum="BE280AE0D5873352" modified="2017-02-15" version="1">MRNKRIICFKYFLTFCFNLMFIKCFIPKTTNSVMKYQKIVLYADTNKKEDLEYKLFKNISFNKIKTNLKNLLVVNKKFTLSDIKHVSFLGKFHNYEKIENYGVNEICILGRSNVGKSTFLRNFIKYLINTNENKFIKVSKNSGCTRSINLYAFENMKKKKLFILTDMPGLGYAEGIGKRKMEILRNNLDDYIFLRNQICLFLILIDMSVDIQKIDISLVKTIKKTNIPFRVICTKSDKYNQSINDRLNAIKNFYKLNKLPINISKFSNYNYINIFKEIQYHCNLNNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZI2</accession>
    <name>A0A1J1GZI2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Kelch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00528000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530504.1">
        <property type="nucleotide sequence ID" value="XM_028674119.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZI2"/>
    <dbReference type="GeneID" id="39733813"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00528000"/>
    <dbReference type="OMA" id="HIDNASG"/>
    <dbReference type="OrthoDB" id="432528at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052637">
        <property type="entry name" value="KLHDC3-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46461">
        <property type="entry name" value="KELCH DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46461:SF4">
        <property type="entry name" value="LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="511"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="575" mass="66101" checksum="8B93E3BC67EBC2E1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZP8</accession>
    <name>A0A1J1GZP8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">separase</fullName>
            <ecNumber evidence="2">3.4.22.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00526500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>All bonds known to be hydrolyzed by this endopeptidase have arginine in P1 and an acidic residue in P4. P6 is often occupied by an acidic residue or by a hydroxy-amino-acid residue, the phosphorylation of which enhances cleavage.</text>
            <dbReference type="EC" id="3.4.22.49"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.22.49" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530490.1">
        <property type="nucleotide sequence ID" value="XM_028674104.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733798"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00526500"/>
    <dbReference type="OMA" id="NNRYTLE"/>
    <dbReference type="OrthoDB" id="10255632at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051307">
        <property type="term" value="P:meiotic chromosome separation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005314">
        <property type="entry name" value="Peptidase_C50"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030397">
        <property type="entry name" value="SEPARIN_core_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12792">
        <property type="entry name" value="EXTRA SPINDLE POLES 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12792:SF0">
        <property type="entry name" value="SEPARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03568">
        <property type="entry name" value="Separin_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51700">
        <property type="entry name" value="SEPARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="315"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1285"/>
            <end position="1305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1443"/>
            <end position="1461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1467"/>
            <end position="1488"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1915"/>
            <end position="1932"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="2045"/>
            <end position="2067"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="2179"/>
            <end position="2197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="2392"/>
            <end position="2412"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C50" evidence="7">
        <location>
            <begin position="4537"/>
            <end position="4739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="723"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="2088"/>
            <end position="2112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="4279"/>
            <end position="4309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="742"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="753"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="4291"/>
            <end position="4303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="4923" mass="596050" checksum="60BF126CA275AD82" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZS1</accession>
    <name>A0A1J1GZS1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L34, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPL34</name>
        <name evidence="5" type="ORF">PGAL8A_00050700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL34 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530869.1">
        <property type="nucleotide sequence ID" value="XM_028674525.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZS1"/>
    <dbReference type="GeneID" id="39729032"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00050700"/>
    <dbReference type="OMA" id="RCHKCVR"/>
    <dbReference type="OrthoDB" id="277449at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.370.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008195">
        <property type="entry name" value="Ribosomal_eL34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038562">
        <property type="entry name" value="Ribosomal_eL34_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018065">
        <property type="entry name" value="Ribosomal_eL34_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10759">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01199">
        <property type="entry name" value="Ribosomal_L34e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01250">
        <property type="entry name" value="RIBOSOMALL34"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01145">
        <property type="entry name" value="RIBOSOMAL_L34E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="107"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="111"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="135"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG98072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="146" mass="16836" checksum="F0D3C87C4981A54B" modified="2017-02-15" version="1">MAQRVHYRKHNHYNTKSNKVKPVKTPGGKLTVHVIKKKAGKPKCADCKCAIQGVKALRPADNHRARKKDRRVSRAYGGSICAKCIRERIMRAFLFEEQKCVRQVLKEKKKQEKKVKKVKKDKKKSSKDGKATDKKVKKNADKKKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZV1</accession>
    <name>A0A1J1GZV1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phytanoyl-CoA dioxygenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00025100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530616.1">
        <property type="nucleotide sequence ID" value="XM_028674244.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZV1"/>
    <dbReference type="GeneID" id="39728774"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00025100"/>
    <dbReference type="OMA" id="YRHCSEN"/>
    <dbReference type="OrthoDB" id="420046at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051961">
        <property type="entry name" value="Fungal_Metabolite_Diox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37563">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G03330)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37563:SF2">
        <property type="entry name" value="PHYTANOYL-COA DIOXYGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G03330)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="537" mass="64089" checksum="F52031C83E4479DA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZV2</accession>
    <name>A0A1J1GZV2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00044000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530806.1">
        <property type="nucleotide sequence ID" value="XM_028674456.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728965"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00044000"/>
    <dbReference type="OMA" id="YHFRILY"/>
    <dbReference type="OrthoDB" id="377917at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23253">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1162"/>
            <end position="1179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1200"/>
            <end position="1218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1263"/>
            <end position="1282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1462"/>
            <end position="1484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2475"/>
            <end position="2494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="658"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="658"/>
            <end position="693"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3785" mass="460376" checksum="576D13488BBC4331" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H013</accession>
    <name>A0A1J1H013_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RAP protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00047900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530841.1">
        <property type="nucleotide sequence ID" value="XM_028674494.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H013"/>
    <dbReference type="GeneID" id="39729004"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00047900"/>
    <dbReference type="OMA" id="EIMVCKL"/>
    <dbReference type="OrthoDB" id="364598at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013584">
        <property type="entry name" value="RAP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08373">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00952">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51286">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="RAP" evidence="4">
        <location>
            <begin position="1044"/>
            <end position="1107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="517"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="647"/>
            <end position="674"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG98044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1119" mass="134576" checksum="98A9DE0B16E6136D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0E5</accession>
    <name>A0A1J1H0E5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00046600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530832.1">
        <property type="nucleotide sequence ID" value="XM_028674484.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728991"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00046600"/>
    <dbReference type="OMA" id="NDLKCIN"/>
    <dbReference type="OrthoDB" id="378920at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="475"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="601"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="731"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="881"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1071"/>
            <end position="1323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1384"/>
            <end position="1460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="475"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="501"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="535"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="601"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="612"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="642"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1071"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1100"/>
            <end position="1180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1203"/>
            <end position="1313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1406"/>
            <end position="1439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1447"/>
            <end position="1460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1584" mass="185904" checksum="40B4FCF274AF4ACA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0H2</accession>
    <name>A0A1J1H0H2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Protein kinase 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PK2</name>
        <name evidence="9" type="ORF">PGAL8A_00460600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529829.1">
        <property type="nucleotide sequence ID" value="XM_028673370.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0H2"/>
    <dbReference type="GeneID" id="39733139"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00460600"/>
    <dbReference type="OMA" id="GHPWFLP"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05117">
        <property type="entry name" value="STKc_CAMK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000571">
        <property type="entry name" value="Maternal embryonic leucine zipper kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050205">
        <property type="entry name" value="CDPK_Ser/Thr_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24349">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="111"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG97026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="507" mass="58804" checksum="E2CA998B4C283AD2" modified="2017-02-15" version="1">MEKRYHQLFKGKRIEFPLATGAASHVSLIYDEKKNPYLLCWTSMYQEKPEFTVPLKGCRIINNITEIGPCVHIITSNEEYQFQCRSKEEYNEMSQFFNMLGYPILGFKNVYVLNKKIGKGSFSTAYIGTNILYGNRVVVKEVDKSKVKESNVYTEIEVLRKVMHKYIIKLISAYEQEGYVYLVLEYLKGGELFEYLNNNGAYPEQIAKKAIKRILIALEALHSNGVVHRDLKMENLMLENPNDPSSLKIIDFGLASFLNSPSMNMRCGSPGYVAPEILKYASYGTKVDIFSLGVILFNILCGYPPFRGNNVKEIFKKNMRCHISFNTKHWLNKSESVKEIILWMCSKNPDDRCTALQALGHPWFLPKFTDMHITANFNDLKNKENILQKVVEQDLCKKCKHYNIENNNNNNNNNNNSISRKNSRSNYKNYKKYFDTMLKIDDKYSDKFIKNKSSNGSISLNRKDYDMYLSNSNEYETVVLHGNYPVPNRSSSLISYNQLKRKNKELI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1U7</accession>
    <name>A0A1J1H1U7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">M1-family alanyl aminopeptidase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PGAL8A_00508000</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530308.1">
        <property type="nucleotide sequence ID" value="XM_028673902.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1U7"/>
    <dbReference type="GeneID" id="39733613"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00508000"/>
    <dbReference type="OMA" id="FKRWYSQ"/>
    <dbReference type="OrthoDB" id="10031169at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09600">
        <property type="entry name" value="M1_APN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1840:FF:000001">
        <property type="entry name" value="Aminopeptidase N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2010.30:FF:000002">
        <property type="entry name" value="Putative aminopeptidase N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2010.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.50.10">
        <property type="entry name" value="Peptidase M1, alanyl aminopeptidase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038438">
        <property type="entry name" value="PepN_Ig-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012779">
        <property type="entry name" value="Peptidase_M1_pepN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024601">
        <property type="entry name" value="Peptidase_M1_pepN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037144">
        <property type="entry name" value="Peptidase_M1_pepN_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035414">
        <property type="entry name" value="Peptidase_M1_pepN_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02414">
        <property type="entry name" value="pepN_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46322">
        <property type="entry name" value="PUROMYCIN-SENSITIVE AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46322:SF1">
        <property type="entry name" value="PUROMYCIN-SENSITIVE AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11940">
        <property type="entry name" value="DUF3458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17432">
        <property type="entry name" value="DUF3458_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 15" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012158949" evidence="10">
        <location>
            <begin position="23"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="domain" description="Aminopeptidase N-like N-terminal" evidence="14">
        <location>
            <begin position="190"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 membrane alanine aminopeptidase" evidence="11">
        <location>
            <begin position="399"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 alanyl aminopeptidase Ig-like fold" evidence="12">
        <location>
            <begin position="625"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 alanyl aminopeptidase C-terminal" evidence="13">
        <location>
            <begin position="723"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="104"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="104"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF11940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF17432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG97507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1060" mass="123508" checksum="325D8CE012442A9C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1Y7</accession>
    <name>A0A1J1H1Y7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">tRNA (adenine(58)-N(1))-methyltransferase</fullName>
            <ecNumber evidence="2 8">2.1.1.220</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00512000</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>adenosine(58) in tRNA + S-adenosyl-L-methionine = N(1)-methyladenosine(58) in tRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:43152"/>
            <dbReference type="Rhea" id="RHEA-COMP:10365"/>
            <dbReference type="Rhea" id="RHEA-COMP:10366"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74491"/>
            <dbReference type="EC" id="2.1.1.220"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.220" evidence="2 8"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530348.1">
        <property type="nucleotide sequence ID" value="XM_028673946.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1Y7"/>
    <dbReference type="GeneID" id="39733653"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00512000"/>
    <dbReference type="OMA" id="RPDHRMI"/>
    <dbReference type="OrthoDB" id="1925287at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031515">
        <property type="term" value="C:tRNA (m1A) methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160107">
        <property type="term" value="F:tRNA (adenine(58)-N1)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049470">
        <property type="entry name" value="TRM61_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014816">
        <property type="entry name" value="tRNA_MeTrfase_Gcd14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12133">
        <property type="entry name" value="TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12133:SF2">
        <property type="entry name" value="TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE CATALYTIC SUBUNIT TRMT61A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08704">
        <property type="entry name" value="GCD14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017269">
        <property type="entry name" value="GCD14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51620">
        <property type="entry name" value="SAM_TRM61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 8" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61 C-terminal" evidence="10">
        <location>
            <begin position="57"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="106"/>
            <end position="109"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR017269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR017269-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG97547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="307" mass="35982" checksum="9AC2C288F7108493" modified="2017-02-15" version="1">MTIKEDSVILYFDEDNIELVKLKKDEITINKKGTFLHNDIIGKEYGSKIFDTLNKNFIYVLKRSPELIALSLKKTTQTLYEHDISFICLLCNALPNKKILEAGTGSGCLTYALANCVLPHGKIYTFEYNEERYKEVKKEFENFDNVKNNINFYHKDIINSDFEDFICDIDSVFLDMPNPWLCVEKIKKVLKERGIFVIFLPSIEQVHKVIDSLEYHSFCEIITYELINKSWQIMFPKNRKNIKNENETTDVNNQSTSTKGYYINSLIPNYRLFQKENKTHTGYLTVAKKPLDDENDQIDIEFKNIIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H281</accession>
    <name>A0A1J1H281_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">WDHD1/CFT4 second beta-propeller domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00501100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530239.1">
        <property type="nucleotide sequence ID" value="XM_028673825.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H281"/>
    <dbReference type="GeneID" id="39733544"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00501100"/>
    <dbReference type="OrthoDB" id="427368at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022100">
        <property type="entry name" value="WDHD1/CFT4_beta-prop_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19932">
        <property type="entry name" value="WD REPEAT AND HMG-BOX DNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19932:SF10">
        <property type="entry name" value="WD REPEAT AND HMG-BOX DNA-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12341">
        <property type="entry name" value="Mcl1_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WDHD1/CFT4 second beta-propeller" evidence="3">
        <location>
            <begin position="631"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="439"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="490"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="587"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="883"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="448"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1230" mass="146276" checksum="13A6BFEC19BECBB3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2H4</accession>
    <name>A0A1J1H2H4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00510700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530335.1">
        <property type="nucleotide sequence ID" value="XM_028673931.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2H4"/>
    <dbReference type="GeneID" id="39733640"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00510700"/>
    <dbReference type="OMA" id="TIKIKYM"/>
    <dbReference type="OrthoDB" id="347158at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="122" mass="14126" checksum="B796FBE181FA61FA" modified="2017-02-15" version="1">MILPITRVVFIKNKSNDKVVKKMKFMCKRNFGGVKFLDTNRTAEETVYFKKEDEALLRNLLKNNPNLNPNYDLTDVESGAENLSNDLSLVFSKYGIKGLNNNLMKDLIKVFELNGYRKMLDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2T6</accession>
    <name>A0A1J1H2T6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Trypsin-like serine protease, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00523800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530463.1">
        <property type="nucleotide sequence ID" value="XM_028674073.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2T6"/>
    <dbReference type="GeneID" id="39733771"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00523800"/>
    <dbReference type="OMA" id="DRYINVD"/>
    <dbReference type="OrthoDB" id="4217619at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22939">
        <property type="entry name" value="SERINE PROTEASE FAMILY S1C HTRA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22939:SF129">
        <property type="entry name" value="SERINE PROTEASE HTRA2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13365">
        <property type="entry name" value="Trypsin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="119"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="5">
        <location>
            <begin position="372"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="458" mass="54065" checksum="8508504A1619D051" modified="2017-02-15" version="1">MKKIYLWVIYCKTKIVWNNSHFLREFYMQNFINHFLNSYNYTMISVKNKMDYLRLYNFSLKNIPLSHCENNNCILSDNDTLDKNTTLKENKKNNFFKLLEYEYLAIKILLYYFKCSLRFLIFTLVHFYLFFYNCFNLVLYILRKKIIYKNKQLNYYFSIPNHLFNSFVTIYKIPKRNNSFDFNFKIDDLTFLGSGFIYDKRGYVLTAAHNVTHLEEGTFIIKNCDDFYLAEVSGLHNESDVCVMKIVSKKKFPHISLDTKRETLKHGELVITFGQIQNFDRETCSIGIVNQPKQTFSKFTNFSEKEQPCLYPFIQISNPINNGMSGSPLIDQNGNLVGMIQKKIDNYGLALPINILKNIAEYLQYKGTYKEPFLGIILKEKEFNIRNSSSSKKELKIYDILSNSPAEISGLKREDVLFSINNKNIKNICEVHEILNSTSDRFIDVEILRQNKKLKFKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H302</accession>
    <name>A0A1J1H302_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00529500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530519.1">
        <property type="nucleotide sequence ID" value="XM_028674136.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H302"/>
    <dbReference type="GeneID" id="39733828"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00529500"/>
    <dbReference type="OMA" id="KVQQRTI"/>
    <dbReference type="OrthoDB" id="443651at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="245" mass="27430" checksum="5DB1EF5CF734FBDE" modified="2017-02-15" version="1">MDMEIKEFDKLSGLRIQCTKDLIFKGSLSAIVGMILGIMCSLIVNCTLVEVSLSKFFSMYFGILFIVVGIIIFWRLNANVVDEAESRRNQLMILSALIILSGILCFFFDRSWLFSLSALSKVPIYCILGISISFALTFSLIDLINYLIGFIQGSITRPLIESKAQVYLILLFTITMGGIFGFIFGLLDVEDESTHHIRLALMKAENCCFPIGTVLGGIAGFGNEVFRQQNEAYKMENVTEFDDEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3D4</accession>
    <name>A0A1J1H3D4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00029000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530655.1">
        <property type="nucleotide sequence ID" value="XM_028674286.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3D4"/>
    <dbReference type="GeneID" id="39728813"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00029000"/>
    <dbReference type="OMA" id="AFKHIIL"/>
    <dbReference type="OrthoDB" id="369546at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="116" mass="13562" checksum="59FB9C3EE2C31371" modified="2017-02-15" version="1">MMEYVSKSDNAYILIKICNLLDLNAINHVKAAIKNIILELFGLSMLLKAKYTILKIIDNNMFFILQTEVRFLSLFLYVIQPNNTKKYEFNLKVLKISNFLSNLTYLSNNILKIENH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H4D9</accession>
    <name>A0A1J1H4D9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Liprin-beta-1/2 coiled-coil domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00064900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028531007.1">
        <property type="nucleotide sequence ID" value="XM_028674679.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H4D9"/>
    <dbReference type="GeneID" id="39729174"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00064900"/>
    <dbReference type="OrthoDB" id="378356at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058914">
        <property type="entry name" value="LIPB1/2_CC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26022">
        <property type="entry name" value="CC_Liprin_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Liprin-beta-1/2 coiled-coil" evidence="2">
        <location>
            <begin position="389"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="333"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="419"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1242" mass="148681" checksum="1016876E0600D440" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2012-05-16" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>H7CDX7</accession>
    <name>H7CDX7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Apicoplast ribosomal protein L6, putative</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">Large subunit ribosomal protein 6</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpl6</name>
        <name evidence="2" type="synonym">RPL6</name>
        <name evidence="2" type="ORF">PGAL8A_API02100</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <geneLocation type="apicoplast" evidence="1"/>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2012" name="Mol. Biol. Evol." volume="29" first="2095" last="2099">
            <title>The Plasmodium Apicoplast Genome: Conserved Structure and Close Relationship of P. ovale to Rodent Malaria Parasites.</title>
            <authorList>
                <person name="Arisue N."/>
                <person name="Hashimoto T."/>
                <person name="Mitsui H."/>
                <person name="Palacpac N.M.Q."/>
                <person name="Kaneko A."/>
                <person name="Kawai S."/>
                <person name="Hasegawa M."/>
                <person name="Tanabe K."/>
                <person name="Horii T."/>
            </authorList>
            <dbReference type="PubMed" id="22396524"/>
            <dbReference type="DOI" id="10.1093/molbev/mss082"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">A8</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">8A</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AB649424">
        <property type="protein sequence ID" value="BAL70747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LN835293">
        <property type="protein sequence ID" value="CRG98236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009325463.1">
        <property type="nucleotide sequence ID" value="NC_031963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="H7CDX7"/>
    <dbReference type="GeneID" id="30315814"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_API02100"/>
    <dbReference type="OMA" id="KFFNYIY"/>
    <dbReference type="OrthoDB" id="387361at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Apicoplast API"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.930.12">
        <property type="entry name" value="Ribosomal protein L6, alpha-beta domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036789">
        <property type="entry name" value="Ribosomal_uL6-like_a/b-dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56053">
        <property type="entry name" value="Ribosomal protein L6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0933">Apicoplast</keyword>
    <keyword evidence="1" id="KW-0934">Plastid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAL70747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="166" mass="20536" checksum="8D88B94F8A5ED851" modified="2012-05-16" version="1">MFNNKYIFLNYIYNNNIYLIFDFKNFDYIYIIVNNKNSEIIKYIYIINNIYIYFNNINKIYFILYKMYEHIFLNINNNLYKLILNIIGINYKFYCIKNYNLLIFQLKYSHKIIIKLPNVIFYKLNLFKNIIYLYSNNLLILNSLGKLINSFQYINKYKELGIRVIK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2021-02-10" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A0K1SC59</accession>
    <accession>A0A1J1H1V6</accession>
    <name>ADA_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Adenosine deaminase</fullName>
            <ecNumber evidence="2">3.5.4.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ADA</name>
    </gene>
    <organism evidence="7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2015" name="Malar. J." volume="14" first="296" last="296">
            <title>De novo assembly and transcriptome analysis of Plasmodium gallinaceum identifies the Rh5 interacting protein (ripr), and reveals a lack of EBL and RH gene family diversification.</title>
            <authorList>
                <person name="Lauron E.J."/>
                <person name="Aw Yeang H.X."/>
                <person name="Taffner S.M."/>
                <person name="Sehgal R.N."/>
            </authorList>
            <dbReference type="PubMed" id="26243218"/>
            <dbReference type="DOI" id="10.1186/s12936-015-0814-0"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [MRNA]</scope>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <reference evidence="3" key="3">
        <citation type="journal article" date="2009" name="Biochemistry" volume="48" first="9618" last="9626">
            <title>Structural and metabolic specificity of methylthiocoformycin for malarial adenosine deaminases.</title>
            <authorList>
                <person name="Ho M.C."/>
                <person name="Cassera M.B."/>
                <person name="Madrid D.C."/>
                <person name="Ting L.M."/>
                <person name="Tyler P.C."/>
                <person name="Kim K."/>
                <person name="Almo S.C."/>
                <person name="Schramm V.L."/>
            </authorList>
            <dbReference type="PubMed" id="19728741"/>
            <dbReference type="DOI" id="10.1021/bi9012484"/>
        </citation>
        <scope>FUNCTION</scope>
        <scope>CATALYTIC ACTIVITY</scope>
        <scope>ACTIVITY REGULATION</scope>
        <scope>BIOPHYSICOCHEMICAL PROPERTIES</scope>
        <scope>PATHWAY</scope>
    </reference>
    <comment type="function">
        <text evidence="2 4">Catalyzes the hydrolytic deamination of adenosine to produce inosine (PubMed:19728741). Unlike other Plasmodium adenosine deaminases, does not catalyze the deamination of 5'-methylthioadenosine (MTA) (PubMed:19728741). Plays an essential role in the purine salvage pathway which allows the parasite to use host cell purines for the synthesis of nucleic acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>adenosine + H2O + H(+) = inosine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:24408"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="2">Inhibited by coformycin but not by methylthiocoformycin (MT-coformycin).</text>
    </comment>
    <comment type="biophysicochemical properties">
        <kinetics>
            <KM evidence="2">32 uM for adenosine (at pH 8)</KM>
            <text evidence="2">kcat is 1.9 sec(-1) with adenosine as substrate.</text>
        </kinetics>
    </comment>
    <comment type="pathway">
        <text evidence="4">Purine metabolism; purine nucleoside salvage.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Unlike other Plasmodium adenosine deaminases, lacks S-methyl-5'-thioadenosine deaminase activity due to the presence of a Glu residue at position 171 instead of an Asp residue.</text>
    </comment>
    <comment type="sequence caution" evidence="3">
        <conflict type="erroneous initiation">
            <sequence resource="EMBL-CDS" id="CRG97310" version="1"/>
        </conflict>
        <text>Extended N-terminus.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.4" evidence="2"/>
    <dbReference type="EMBL" id="KP164513">
        <property type="protein sequence ID" value="AKV72186.1"/>
        <property type="molecule type" value="mRNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97310.1"/>
        <property type="status" value="ALT_INIT"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A0K1SC59"/>
    <dbReference type="SMR" id="A0A0K1SC59"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00488900"/>
    <dbReference type="UniPathway" id="UPA00606"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009897">
        <property type="term" value="C:external side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004000">
        <property type="term" value="F:adenosine deaminase activity"/>
        <property type="evidence" value="ECO:0000314"/>
        <property type="project" value="UniProtKB"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006154">
        <property type="term" value="P:adenosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043103">
        <property type="term" value="P:hypoxanthine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046103">
        <property type="term" value="P:inosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060169">
        <property type="term" value="P:negative regulation of adenosine receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009168">
        <property type="term" value="P:purine ribonucleoside monophosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006650">
        <property type="entry name" value="A/AMP_deam_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001365">
        <property type="entry name" value="A_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006330">
        <property type="entry name" value="Ado/ade_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01430">
        <property type="entry name" value="aden_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11409">
        <property type="entry name" value="ADENOSINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11409:SF43">
        <property type="entry name" value="ADENOSINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00962">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00485">
        <property type="entry name" value="A_DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at protein level"/>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0660">Purine salvage</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_0000451866" description="Adenosine deaminase">
        <location>
            <begin position="1"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Gating helix loop; regulates binding affinity for substrates and thus substrate selectivity" evidence="1">
        <location>
            <begin position="169"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="43"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>a purine D-ribonucleoside</name>
            <dbReference type="ChEBI" id="CHEBI:142355"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>a purine D-ribonucleoside</name>
            <dbReference type="ChEBI" id="CHEBI:142355"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>a purine D-ribonucleoside</name>
            <dbReference type="ChEBI" id="CHEBI:142355"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>a purine D-ribonucleoside</name>
            <dbReference type="ChEBI" id="CHEBI:142355"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>a purine D-ribonucleoside</name>
            <dbReference type="ChEBI" id="CHEBI:142355"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1">
        <source>
            <dbReference type="UniProtKB" id="A5KE01"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="2">
        <source>
            <dbReference type="PubMed" id="19728741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <evidence type="ECO:0000305" key="4">
        <source>
            <dbReference type="PubMed" id="19728741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000312" key="5">
        <source>
            <dbReference type="EMBL" id="AKV72186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000312" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="AKV72186.1"/>
        </source>
    </evidence>
    <sequence length="362" mass="42492" checksum="2EF8886153E72C03" modified="2015-11-11" version="1">MTILHEEINFLKKDELNINLKCLDKKERYKIWRRIPKCELHCHLDLCFSLEFFLKCVRKYNLQPDLTDDEVVDYYLFKDKGKSLNEFIERSRRVTDIFINYDIIKDIAKNAVFNKYKEGVILIEFRYSPSYIAYKYNLCIDLIHKTIVEGINEAVEKLNHKIHVGLICIGETGISEESLRKAAEFCVKNKKDFVGFDHAGHERDLKPYKEIYDYVRENGIPLTIHAGEDLTLPNLNTIYSAIEVLKAKRIGHGIRVIESEDLINLIKKNDILLEICPISNLLLNNVKSMDTHPIKKLYDSGIKVSVNTDDPGMFLTEINDEYEELYLNLNFNLEDFMKMNLWALEKSFVKSEIKDKLKKLYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLC7</accession>
    <name>A0A1J1GLC7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00083500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525953.1">
        <property type="nucleotide sequence ID" value="XM_028670832.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLC7"/>
    <dbReference type="GeneID" id="39729359"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00083500"/>
    <dbReference type="OrthoDB" id="368608at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="105" mass="12960" checksum="ACE8ED8E1E74B245" modified="2017-02-15" version="1">MSKSNTCRCDMSAYARNRFYNPKVHVSGWYDIQNDEDYLESYNKMKDFYLQEYPTYKIEEKYKNMKKKCIKNISDKQVIFYQDYGTEYWVTETKESYKVHNKIEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLD0</accession>
    <name>A0A1J1GLD0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00091800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526036.1">
        <property type="nucleotide sequence ID" value="XM_028671755.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLD0"/>
    <dbReference type="GeneID" id="39729442"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00091800"/>
    <dbReference type="OMA" id="IDINVRE"/>
    <dbReference type="OrthoDB" id="378605at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="587" mass="70344" checksum="F6753BB9203DB16D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLG3</accession>
    <name>A0A1J1GLG3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA polymerase delta subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00074900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525867.1">
        <property type="nucleotide sequence ID" value="XM_028675123.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLG3"/>
    <dbReference type="GeneID" id="39729274"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00074900"/>
    <dbReference type="OMA" id="HSITIIW"/>
    <dbReference type="OrthoDB" id="381955at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043625">
        <property type="term" value="C:delta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904161">
        <property type="term" value="P:DNA synthesis involved in UV-damage excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006297">
        <property type="term" value="P:nucleotide-excision repair, DNA gap filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019038">
        <property type="entry name" value="POLD3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17598">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17598:SF13">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="418"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="458" mass="53460" checksum="B9B80BB596F27AD8" modified="2017-02-15" version="1">MNTQSVKNITSIEELLFLYDSLINDGHVITVVNVKNSLKLPSDLSQKFMNYYYGNRKDQLSVTYLVEGYKKDSNEYICAILTQKEVLELQKEQNEYSIKIYSIQSNKSKIDLSVLWKQEINELNKVFENTDLKNQLLIPQFSDIILGDLEVKNVENNLNSQHSFLQNEKEIKDNNRKINVKETDNNKNKDDNNVDKKIDSISEYKIKDRIDDERTKTLIKKEIHIEDKDSNESEQLKKNIENDYSKIVNSFRNENSNLSNDSDNFKQSSNVSNKRKLEDSNSYKIKRENLTVDSVNNEINKPICEVNSKTMNKSKPNKSENETLTNNILIKKEKKIDESNKNRIETKLKKTKLEIKKTDVKPELFQSDSSDDNENKILEENEKPLKTFPKIKSVKETQMFYENGYLVTVDKDSCIHIDSSESNNNDPKKVIKDTTSSNNKKRKNLQQTLLTNFFKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLU4</accession>
    <name>A0A1J1GLU4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00105850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526175.1">
        <property type="nucleotide sequence ID" value="XM_028673298.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLU4"/>
    <dbReference type="GeneID" id="39729584"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00105850"/>
    <dbReference type="OMA" id="RYHSIKT"/>
    <dbReference type="OrthoDB" id="419606at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="166" mass="19323" checksum="5F57CE1B4BC6E5A3" modified="2017-02-15" version="1">MSYIKAPSDITILEYKYSKNNKKRKINFLKKLFIHCSFFTIGNNCNKLNNHDVIKILSNIYSDNGLDNKNMNTINILNILNTRQKDVEKQVKCKMCSLMGFLLLPLYSFKHFRYYDAKSKIIILPFFSIAGIYLGSFFGNLITGRFSDYKRSKFLGTLPANVFLKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLX2</accession>
    <name>A0A1J1GLX2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">N-acetyltransferase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00105400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526170.1">
        <property type="nucleotide sequence ID" value="XM_028673243.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLX2"/>
    <dbReference type="GeneID" id="39729579"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00105400"/>
    <dbReference type="OMA" id="EQHPSMR"/>
    <dbReference type="OrthoDB" id="10264728at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031416">
        <property type="term" value="C:NatB complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004596">
        <property type="term" value="F:protein-N-terminal amino-acid acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000124">
        <property type="entry name" value="N-acetyltransferase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051646">
        <property type="entry name" value="NatB_acetyltransferase_subunit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45910">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45910:SF1">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="2"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="155" mass="18308" checksum="02E2BE9B2618B9D0" modified="2017-02-15" version="1">MASYQYFSYIDLYKINNVNLDPFTEVFNDKFYLRYIYKWPHMNIVSKDMDDHISGYIIGKEEGYGEEYHGHVTALSIEEDGRRTGKGIGLMNEFEKISKIIHKGYFVDLFVRISNDPAINMYKKLGYIINEEITNYYCGNESALDMRKYLNLEKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLX6</accession>
    <name>A0A1J1GLX6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00112800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526244.1">
        <property type="nucleotide sequence ID" value="XM_028674065.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLX6"/>
    <dbReference type="GeneID" id="39729653"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00112800"/>
    <dbReference type="OMA" id="CHKNFDC"/>
    <dbReference type="OrthoDB" id="377693at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1143"/>
            <end position="1164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1072"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="136"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="391"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="497"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1241" mass="149377" checksum="D902EACCDAC7AEF9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM10</accession>
    <name>A0A1J1GM10_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00113100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526247.1">
        <property type="nucleotide sequence ID" value="XM_028674099.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM10"/>
    <dbReference type="GeneID" id="39729656"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00113100"/>
    <dbReference type="OrthoDB" id="370704at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013085607" evidence="2">
        <location>
            <begin position="18"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="342" mass="41633" checksum="EBAE9CA6BE944B28" modified="2017-02-15" version="1">MNFVFFIFLKFFITINAFKYYKYKKNENKNYFLFLNRCSKIYKPKNIYKIILFKKPYFQNNKNNFKLYIHTLDKGEDNNFLSINNFNKKEKTKKRKSFKDISYNSDSVKDVLKKTKKFCNYLTNKLGRLNKKLREIKKLETVFYASPNILTESQKVKISKKKQIKNEIVLINRYRKKYISYKRNLMKNKDDLSPFFYSKKKLKKKKEFCTPEEFREILKSNDYKATIQRIKRIDIQKIPKNITDFLVFNKYGSREEIKILFGLKAIKINGNTIDDENYILNLKEDKVKVFDQDVNIHEDHYAIRKRFTKDQKRILNEKKEENISDIKKDIKELEKFFKIKNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM46</accession>
    <name>A0A1J1GM46_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00113400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526250.1">
        <property type="nucleotide sequence ID" value="XM_028674132.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM46"/>
    <dbReference type="GeneID" id="39729659"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00113400"/>
    <dbReference type="OrthoDB" id="391560at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="243"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="458" mass="56426" checksum="3CE1373217255887" modified="2017-02-15" version="1">MNTKVKYHRNFFCNNLFKHSYNNVFLTYKKHFSYIKKIEELKKRILDYYSKDNEYFLQRRKQHEKEIKNYFKELSNYVTLEDIFFCPDEKRILNEETENIKKYIEDNNKKNLKDINDHIKITNEKTELMKILSICGIRIPPKILFYYIFDIISNLKKHLDINKNYIIKYEAVTEKENYFRINQYYYNKKKINVQFFLLYKSLSNVLYSICENSIDNSEIYLSIRDEIYENYCNLSDIIIKSPSFLNVSILFYFINVWLFSDKSRKMKIRCLENLNKYINSISDDEININKDDLFYFFLTIRLFFFTFSYSDVLNNLNNYSKHFISSVLFFPHNSEKTTNQENENYKYIINYLNKNEKYVEFRKIQVFPFNFSLSSLKNKIIYIFERPDDYYENDTNVMRSYNYWKYFIAKKEDFKLLTICNKHEFNELYDTNKRDDILTKYVNKDYLYNFEEKIKKDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMA2</accession>
    <name>A0A1J1GMA2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00119000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526306.1">
        <property type="nucleotide sequence ID" value="XM_028674702.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMA2"/>
    <dbReference type="GeneID" id="39729715"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00119000"/>
    <dbReference type="OMA" id="VSYATHQ"/>
    <dbReference type="OrthoDB" id="361676at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013380397" description="PH domain-containing protein" evidence="2">
        <location>
            <begin position="26"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="355"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="400"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="414" mass="48793" checksum="9D7339DB74AD786C" modified="2017-02-15" version="1">MKHSKFLLNVYIFSLFFLLNNKIKCQTFLPVSYPTHHLYSFEKLTPHDIRSNLKRTISNFITTKLENIKNKFQKNDKNNDIKNEYETSLEDQIKSLLQQAKNKRTLSKKIKESYDRALKNLKKKQSGVDEEKIIKILEHNLEQINYLNKKSHYLEKKAEYLKKNLENTNNENSKQNNNCNISKTGKLKFVTSSNGLKHSINNVQGNINQNGFTIFHKNKKKMMYYWNIIELPIKVIGSIEQCFFFIYRNNNQIFCTDNKLKSHSWINSLSEASLCYNFGIKGIIINNNIINDKLIKKNKINENILTVDIKPEENSTRILVNDVEQKLENNNGVINLNKIKKKIEDEKKINKKSEIINGINDKKESQKENSDENKENDKNKENDKNKENDKNKEDDKNKEDDENEEDDENEEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMF1</accession>
    <name>A0A1J1GMF1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00128400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526399.1">
        <property type="nucleotide sequence ID" value="XM_028674805.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMF1"/>
    <dbReference type="GeneID" id="39729809"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00128400"/>
    <dbReference type="OMA" id="MVYKHIA"/>
    <dbReference type="OrthoDB" id="392797at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="306"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1022" mass="124280" checksum="6322E770BD2AB3BA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GML8</accession>
    <name>A0A1J1GML8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cyclin, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00128600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526401.1">
        <property type="nucleotide sequence ID" value="XM_028674807.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729811"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00128600"/>
    <dbReference type="OMA" id="FLKVRND"/>
    <dbReference type="OrthoDB" id="5590282at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2205"/>
            <end position="2234"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1222"/>
            <end position="1249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2350" mass="283443" checksum="F66D85C9F8EB6207" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN14</accession>
    <name>A0A1J1GN14_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SURP motif domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00152700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526639.1">
        <property type="nucleotide sequence ID" value="XM_028675071.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN14"/>
    <dbReference type="GeneID" id="39730051"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00152700"/>
    <dbReference type="OMA" id="QYGSKEY"/>
    <dbReference type="OrthoDB" id="5836667at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="97"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="277" mass="33638" checksum="35DAC190379EA526" modified="2017-02-15" version="1">MSFNNFNKEPPPEYLNHIYESDIVEFYLKLDNDLLIKFPFLHVDHPLHEYYQFIKLNTTKRIIKKYPNFIPRSLKNLFEFVVELENKKVTKNETTTKILKEKQMKNLKEKKKKKDEEKDQSYSTLFMKYMESDEESDKTIKEEKEEKEDLTNNENFKEVDDIVNKFPPKNESSNNYLQFLIRCIENLKYLQYGSKEYDYFTKKLLCSKSDSNFISRKITSIDFLTFIYKLDEYKINFENICGNINEDEKVEEKDNLKMIQDYRRERAKLILHGFKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN69</accession>
    <name>A0A1J1GN69_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00162000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526732.1">
        <property type="nucleotide sequence ID" value="XM_028675174.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN69"/>
    <dbReference type="GeneID" id="39730145"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00162000"/>
    <dbReference type="OMA" id="TIEITRM"/>
    <dbReference type="OrthoDB" id="375620at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="577" mass="68957" checksum="88C0C85992486E5C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNE1</accession>
    <name>A0A1J1GNE1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00169000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526804.1">
        <property type="nucleotide sequence ID" value="XM_028670009.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNE1"/>
    <dbReference type="GeneID" id="39730217"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00169000"/>
    <dbReference type="OMA" id="NTCIQRN"/>
    <dbReference type="OrthoDB" id="370557at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="263" mass="31328" checksum="39FFA0EC5D8B29DA" modified="2017-02-15" version="1">METLDYRWNDKIENFNLKINKLRNEINDFKKNSINAYSLKNKNVYFSKLNNNVKRRELININNYEVRNYLNKTNNTTYILKDDKNSKMVNVIFPTSKNTSNKIIKTNDRKFCENKSLTKFNLRNKRKNEKVIKINEKRWLIATKHAKVKKLDTTEKENLENKKSGKNRFLYLEGEEGNLHVYPVYSDSEVGFESISQIEDESLSKIKKENQDDDDIETTKHLAQWSSDLVHKYLLEAIENTKLIFKCSNVKCRHEEIFKRIQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNF1</accession>
    <name>A0A1J1GNF1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Actin-depolymerizing factor 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ADF2</name>
        <name evidence="4" type="ORF">PGAL8A_00167800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the actin-binding proteins ADF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526791.1">
        <property type="nucleotide sequence ID" value="XM_028669995.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNF1"/>
    <dbReference type="GeneID" id="39730204"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00167800"/>
    <dbReference type="OMA" id="GYVYKHS"/>
    <dbReference type="OrthoDB" id="10249245at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015629">
        <property type="term" value="C:actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030042">
        <property type="term" value="P:actin filament depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11286">
        <property type="entry name" value="ADF_cofilin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.20.10">
        <property type="entry name" value="Severin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002108">
        <property type="entry name" value="ADF-H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029006">
        <property type="entry name" value="ADF-H/Gelsolin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017904">
        <property type="entry name" value="ADF/Cofilin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11913">
        <property type="entry name" value="COFILIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00241">
        <property type="entry name" value="Cofilin_ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00102">
        <property type="entry name" value="ADF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55753">
        <property type="entry name" value="Actin depolymerizing proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51263">
        <property type="entry name" value="ADF_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADF-H" evidence="3">
        <location>
            <begin position="4"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="143" mass="16653" checksum="64C3A682C531A86D" modified="2017-02-15" version="1">MVSGVKVSDECVYEFNKLKIKHLHKYIIFRIENCEEVIVDLLEQDIELKSYSDIITNIKNNLKTTECRYIIADIPVPTPEGVLRNRIYFIFWSPSLAKSKEKMLYATSKESLVRKINGIFKSLEITCDLEEFEEELTGIILNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNK1</accession>
    <name>A0A1J1GNK1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cytochrome c oxidase subunit 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00168100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>4 Fe(II)-[cytochrome c] + O2 + 8 H(+)(in) = 4 Fe(III)-[cytochrome c] + 2 H2O + 4 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:11436"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="7.1.1.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="2">
            <dbReference type="Rhea" id="RHEA:11437"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526794.1">
        <property type="nucleotide sequence ID" value="XM_028669998.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNK1"/>
    <dbReference type="GeneID" id="39730207"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00168100"/>
    <dbReference type="OMA" id="NIPFWSR"/>
    <dbReference type="OrthoDB" id="412083at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002429">
        <property type="entry name" value="CcO_II-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01166">
        <property type="entry name" value="CYCOXIDASEII"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50857">
        <property type="entry name" value="COX2_CUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome oxidase subunit II copper A binding" evidence="4">
        <location>
            <begin position="200"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00049512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="227" mass="27315" checksum="EC8A35269ECC1666" modified="2017-02-15" version="1">MFKFNSKLYFGLRNINHLIINQKIPYLKPYYIKKNQLICNNFSTVNKKVTSNANEIKNKEEIHIENAHGHEVHTKGLYHHIDHHHGNPRDHLNEDGTRKYEYDFDNYHWDDYWSSTPKQNIVIVNGQKMIKGEETKPFEYLFNVSQHNIPFWSRTRLNVWGNYNMVLKVEFLFFWIPTLIIMSIAVPCFTMLYMLDEIVHTTMTVKVIGRQWYWVYEVESPPEEDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNV4</accession>
    <name>A0A1J1GNV4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00384200</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526959.1">
        <property type="nucleotide sequence ID" value="XM_028670181.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732372"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00384200"/>
    <dbReference type="OMA" id="YHISCAT"/>
    <dbReference type="OrthoDB" id="20839at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15571">
        <property type="entry name" value="ePHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd15522">
        <property type="entry name" value="PHD_TAF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034732">
        <property type="entry name" value="EPHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13771">
        <property type="entry name" value="zf-HC5HC2H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13832">
        <property type="entry name" value="zf-HC5HC2H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51805">
        <property type="entry name" value="EPHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="8">
        <location>
            <begin position="2165"/>
            <end position="2274"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="7">
        <location>
            <begin position="3538"/>
            <end position="3599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="314"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1507"/>
            <end position="1532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1780"/>
            <end position="2036"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="2918"/>
            <end position="2938"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="3423"/>
            <end position="3454"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1042"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="314"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="339"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1507"/>
            <end position="1521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1522"/>
            <end position="1532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1785"/>
            <end position="1796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1815"/>
            <end position="1826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1849"/>
            <end position="1859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1860"/>
            <end position="2036"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="2918"/>
            <end position="2933"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="3431"/>
            <end position="3449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="3599" mass="424482" checksum="D7B3B300B554854E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNY6</accession>
    <name>A0A1J1GNY6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Merozoite surface protein MSA180</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00390300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527020.1">
        <property type="nucleotide sequence ID" value="XM_028670249.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNY6"/>
    <dbReference type="GeneID" id="39732433"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00390300"/>
    <dbReference type="OMA" id="AVEPNHA"/>
    <dbReference type="OrthoDB" id="376203at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012814263" description="Merozoite surface protein MSA180" evidence="2">
        <location>
            <begin position="25"/>
            <end position="1280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="283"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1280" mass="153457" checksum="78AB9EC543C0901A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNY7</accession>
    <name>A0A1J1GNY7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">B30.2/SPRY domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00390500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527022.1">
        <property type="nucleotide sequence ID" value="XM_028670251.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732435"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00390500"/>
    <dbReference type="OrthoDB" id="25503at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12885">
        <property type="entry name" value="SPRY_RanBP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001870">
        <property type="entry name" value="B30.2/SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013144">
        <property type="entry name" value="CRA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044736">
        <property type="entry name" value="Gid1/RanBPM/SPLA_SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003877">
        <property type="entry name" value="SPRY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039190">
        <property type="entry name" value="TTC14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23184">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23184:SF9">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00622">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00757">
        <property type="entry name" value="CRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00449">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50188">
        <property type="entry name" value="B302_SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="425"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="642"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="domain" description="B30.2/SPRY" evidence="3">
        <location>
            <begin position="1384"/>
            <end position="1570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="937"/>
            <end position="1370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1912"/>
            <end position="1967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="949"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="972"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="987"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1001"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1192"/>
            <end position="1262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1270"/>
            <end position="1319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1320"/>
            <end position="1340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1341"/>
            <end position="1350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2620" mass="315139" checksum="08203E78FA789637" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP65</accession>
    <name>A0A1J1GP65_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00399100</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527108.1">
        <property type="nucleotide sequence ID" value="XM_028670347.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP65"/>
    <dbReference type="GeneID" id="39732521"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00399100"/>
    <dbReference type="OMA" id="FRVHTYR"/>
    <dbReference type="OrthoDB" id="413582at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005956">
        <property type="term" value="C:protein kinase CK2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000776">
        <property type="entry name" value="Cdc2-related protein kinase 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045216">
        <property type="entry name" value="CK2_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24054">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24054:SF0">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="675"/>
            <end position="1217"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="705"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG94287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1240" mass="147197" checksum="064DAA7A1B66EE93" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP83</accession>
    <name>A0A1J1GP83_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00381400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526931.1">
        <property type="nucleotide sequence ID" value="XM_028670150.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP83"/>
    <dbReference type="GeneID" id="39732344"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00381400"/>
    <dbReference type="OrthoDB" id="372737at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="61" mass="7351" checksum="DFAA54FED47DB3F8" modified="2017-02-15" version="1">MDKNLHENKNLTNYEMQLVKAKKVVSKLEKLEIDFYTELIKLNILKRNTNIDIYKKIINEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPH3</accession>
    <name>A0A1J1GPH3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribosomal protein L7/L12, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00402900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527146.1">
        <property type="nucleotide sequence ID" value="XM_028670389.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPH3"/>
    <dbReference type="GeneID" id="39732559"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00402900"/>
    <dbReference type="OMA" id="ICFFQIC"/>
    <dbReference type="OrthoDB" id="250175at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00387">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1390.10:FF:000001">
        <property type="entry name" value="50S ribosomal protein L7/L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000206">
        <property type="entry name" value="Ribosomal_bL12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013823">
        <property type="entry name" value="Ribosomal_bL12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_bL12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987:SF4">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL12M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00542">
        <property type="entry name" value="Ribosomal_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="ClpS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein bL12 C-terminal" evidence="5">
        <location>
            <begin position="173"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="138"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="138"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="151"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG94325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="239" mass="27976" checksum="E3614F1FD32DB690" modified="2017-02-15" version="1">MKKYKFLLKRYLSNFYDFRNISYNNFNRNGITNKFLLKRYFSNFDVFDKIKDVNNSNNNEVTSELKRKPSKKVVKLVDEILNLTLIEAADLCDLCQEKLEGNKSFNNSLFMNRNPFPHPSHFFNAGHFSPLNQNNINNTPTNNNVKNSNSVEEKESKEEKQNENKKITKSTYNIKLEKFDVKNKINTIKEIRKLTNVGLKEAKDMVESAPFYIQKNVPVEKADEIKKKFEELGATIILE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPK5</accession>
    <name>A0A1J1GPK5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein eS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00393400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eukaryotic ribosomal protein eS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527051.1">
        <property type="nucleotide sequence ID" value="XM_028670283.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPK5"/>
    <dbReference type="GeneID" id="39732464"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00393400"/>
    <dbReference type="OMA" id="MHNDESD"/>
    <dbReference type="OrthoDB" id="9834376at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03122">
        <property type="entry name" value="Ribosomal_eS1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001593">
        <property type="entry name" value="Ribosomal_eS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027500">
        <property type="entry name" value="Ribosomal_eS1_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11830">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S3A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01015">
        <property type="entry name" value="Ribosomal_S3Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01397">
        <property type="entry name" value="Ribosomal_S3Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="initiator methionine" description="Removed" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="262" mass="30097" checksum="E3477DD82D53A157" modified="2017-02-15" version="1">MAVGKNKRTSKGKKGGKKKVTDVFTKKEWYDLKAPKMFLVRNFGKTLVTKTIGKKLATDSLRGRIYEVNLADLNNDEDQAHKKIKLSCEHIINRDCYTDFCGLSITRDKLCSLIRKGYTLIEGFTDVKTIDNYHLRMFCIAFTKKRQNQTKTTCYAQTSQIKKIRKKMVDIMNAEASKVLLKDLVKKFIPESIGKEIEKQCKKIFPLQNVLIRKVKILKKPKLDISKLMELHTEPKEDSGKNVKALPESKEATNILTAELKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPZ7</accession>
    <name>A0A1J1GPZ7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00080100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Non-catalytic component of the proteasome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase T1B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525920.1">
        <property type="nucleotide sequence ID" value="XM_028670466.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPZ7"/>
    <dbReference type="GeneID" id="39729325"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00080100"/>
    <dbReference type="OMA" id="INEQIVM"/>
    <dbReference type="OrthoDB" id="10248542at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03760">
        <property type="entry name" value="proteasome_beta_type_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016295">
        <property type="entry name" value="Proteasome_beta4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF6">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001213">
        <property type="entry name" value="Psome_endopept_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 4 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR001213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="256" mass="29802" checksum="1BDBF08CAD4D4299" modified="2017-02-15" version="1">MTLGPVVTGTSVIALKYQNGIMIAADRKASYGSYAKFQNVERIFKINNKTVMSFSGELADAQYIYELLTRVNVNNVTERKSKYDIHNPKYYHSYVSRIFYNRKNRIDPLFNNIIIAGINSQEYDDNDKNILLYTEKKNEQEYKIIDKNDLYIGFVDMHGTQFCGDYMTTGYARYFALTLLRNHYKDNMNEQEARNLLNECLKILYFRDATASNKIQIVKITSKGVEYDDPYILPCDLNSKDYIYPSTLLPPTGCMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ40</accession>
    <name>A0A1J1GQ40_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dynactin subunit 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00111300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526229.1">
        <property type="nucleotide sequence ID" value="XM_028673899.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ40"/>
    <dbReference type="GeneID" id="39729638"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00111300"/>
    <dbReference type="OMA" id="PTIGDHN"/>
    <dbReference type="OrthoDB" id="2355at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005869">
        <property type="term" value="C:dynactin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070840">
        <property type="term" value="F:dynein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027777">
        <property type="entry name" value="DCTN6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13072">
        <property type="entry name" value="DYNACTIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13072:SF0">
        <property type="entry name" value="DYNACTIN SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="556" mass="66293" checksum="2495D2C83225E0F7" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ94</accession>
    <name>A0A1J1GQ94_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Metallo-hydrolase/oxidoreductase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00183000</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527259.1">
        <property type="nucleotide sequence ID" value="XM_028670514.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ94"/>
    <dbReference type="GeneID" id="39730357"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00183000"/>
    <dbReference type="OMA" id="YNIEHIC"/>
    <dbReference type="OrthoDB" id="527344at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042781">
        <property type="term" value="F:3'-tRNA processing endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01818">
        <property type="entry name" value="RNase_Z_BN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013471">
        <property type="entry name" value="RNase_Z/BN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46018">
        <property type="entry name" value="ZINC PHOSPHODIESTERASE ELAC PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46018:SF2">
        <property type="entry name" value="ZINC PHOSPHODIESTERASE ELAC PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23023">
        <property type="entry name" value="Anti-Pycsar_Apyc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="216"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG94438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="898" mass="106396" checksum="8EB54F9E8458BB7E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQB2</accession>
    <name>A0A1J1GQB2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00212200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527540.1">
        <property type="nucleotide sequence ID" value="XM_028670826.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQB2"/>
    <dbReference type="GeneID" id="39730649"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00212200"/>
    <dbReference type="OMA" id="YYDNFAG"/>
    <dbReference type="OrthoDB" id="370586at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="683"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="98"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="249"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="683"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="721"/>
            <end position="732"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="869" mass="103193" checksum="2BDB11F728273226" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQC9</accession>
    <name>A0A1J1GQC9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">LCCL-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00210800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527526.1">
        <property type="nucleotide sequence ID" value="XM_028670811.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQC9"/>
    <dbReference type="GeneID" id="39730635"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00210800"/>
    <dbReference type="OMA" id="YYDNAYF"/>
    <dbReference type="OrthoDB" id="441660at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.10.10">
        <property type="entry name" value="Fibronectin, type II, collagen-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.182.10">
        <property type="entry name" value="Toxin - Anthrax Protective Antigen,domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036943">
        <property type="entry name" value="FN_type2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037524">
        <property type="entry name" value="PA14/GLEYA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011658">
        <property type="entry name" value="PA14_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07691">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00758">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56988">
        <property type="entry name" value="Anthrax protective antigen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51820">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012904641" evidence="1">
        <location>
            <begin position="21"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="domain" description="PA14" evidence="2">
        <location>
            <begin position="215"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="857" mass="98921" checksum="7CA96016016B8174" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQL4</accession>
    <name>A0A1J1GQL4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00220400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527622.1">
        <property type="nucleotide sequence ID" value="XM_028670917.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQL4"/>
    <dbReference type="GeneID" id="39730731"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00220400"/>
    <dbReference type="OMA" id="LCYFVQP"/>
    <dbReference type="OrthoDB" id="370514at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000077">
        <property type="term" value="P:DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.70.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046938">
        <property type="entry name" value="DNA_clamp_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55979">
        <property type="entry name" value="DNA clamp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="374" mass="44931" checksum="713652DC6E7F34A9" modified="2017-02-15" version="1">MNYDISTNYNFSVKNVNFFKNALSLLNVDDNKYNSNFKKGTDNFLEGENLILFNLYYDGIKLRSLSKCKQIYCFLYMDSNCFTSYNFFEKEEDEKKYEVEYNKYETNSVNSDNLFTTHVIDDEREDVVKLKTVSPLKMNSVQKSENEDEYNIRKKIYTDVDEKKNYIEFLVSPYELLRALEFLDAVILNIKFDYSNKKLILQLTDEDGDTSETFIKIIVDYYYEIYKLEKYSFLNNNYNYFSLQSEIFSFYLEYLIKCNDQYITFYINEYANDNTSILKMETKNKNYERAVQLMPKETFDEFKSLKNQMFKYRIKDLSKINQALKISSHLRMDFQENGLLRFQFTLREYNLNGTHLCYFIQPLPDFNTLNGNEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRB4</accession>
    <name>A0A1J1GRB4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Meiotic nuclear division protein 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MND1</name>
        <name evidence="9" type="ORF">PGAL8A_00220900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the MND1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527627.1">
        <property type="nucleotide sequence ID" value="XM_028670923.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRB4"/>
    <dbReference type="GeneID" id="39730736"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00220900"/>
    <dbReference type="OMA" id="VCYWAFP"/>
    <dbReference type="OrthoDB" id="273345at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040661">
        <property type="entry name" value="LZ3wCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005647">
        <property type="entry name" value="Mnd1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040453">
        <property type="entry name" value="Mnd1_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18517">
        <property type="entry name" value="LZ3wCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03962">
        <property type="entry name" value="Mnd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026991">
        <property type="entry name" value="Mnd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mnd1 HTH" evidence="7">
        <location>
            <begin position="16"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="Leucine zipper with capping helix" evidence="8">
        <location>
            <begin position="150"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="73"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR026991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF18517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="204" mass="24368" checksum="564AA3261602BF06" modified="2017-02-15" version="1">MKRKGKSNDDKKLILYDLMLQSESFFILKELEVLSQKKGIRSIFVKDLLQQLVDDNKVKSEKVGLQNIFWVLKTEESSNLENEYQKLKEKKEEYEEIIKTEKDIYDKLFDTLKFSEDELKSKIGEVKELIQLLDKKKIELKNLKKTDIKQIEKMQIQNKCAIESIERWNNNIFIVKQWIQNKTDKPGEIVDRLLGVKDIFHNWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRK8</accession>
    <name>A0A1J1GRK8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Protein transport protein SEC61 subunit alpha, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">SEC61</name>
        <name evidence="13" type="ORF">PGAL8A_00257200</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the SecY/SEC61-alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527980.1">
        <property type="nucleotide sequence ID" value="XM_028671316.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRK8"/>
    <dbReference type="GeneID" id="39731100"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00257200"/>
    <dbReference type="OMA" id="PMMRQMF"/>
    <dbReference type="OrthoDB" id="420669at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3370.10:FF:000010">
        <property type="entry name" value="Protein transport protein SEC61 subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3370.10">
        <property type="entry name" value="SecY subunit domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002208">
        <property type="entry name" value="SecY/SEC61-alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030659">
        <property type="entry name" value="SecY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023201">
        <property type="entry name" value="SecY_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019561">
        <property type="entry name" value="Translocon_Sec61/SecY_plug_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00967">
        <property type="entry name" value="3a0501s007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006341">
        <property type="entry name" value="PRK08568.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10906">
        <property type="entry name" value="SECY/SEC61-ALPHA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10559">
        <property type="entry name" value="Plug_translocon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00344">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004557">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103491">
        <property type="entry name" value="Preprotein translocase SecY subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00755">
        <property type="entry name" value="SECY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00756">
        <property type="entry name" value="SECY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="115"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="416"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="440"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="Translocon Sec61/SecY plug" evidence="12">
        <location>
            <begin position="39"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF10559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG95167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="472" mass="52268" checksum="AC4F485C8DABF605" modified="2017-02-15" version="1">MVRFLNLIKPVMFLLPEVQSPDRKLPFKEKLLWTAVSLFVFLICCQIPLYGIVTSKSSDPFYWMRVILASNRGTLMELGISPIVTSGMVMQLLAGSKIIDVDQSLKEDRTLFQGAQKLLGLLITLGEAIAYVISGIYGNISEIGTGHAIIIILQLFFAGVVVILLDELLQKGYGLGSGISLFIATNICETIMWKSFSPTTINTDKGIEFEGAIISLIYCLFTESNKISALKKAFYRTHAPNVTNLLATILVFLIVIYLQGFRVDLSVKYQSVRGQQGTYPIKLFYTSNIPIILQTALVSNLYFFSQILYKRFKNSILVNLLGQWQEIESSGTSIPIGGIAYYISPPNSFADITNDPFHTLVYISFVLVACAFFSKTWIEVSGSSAKDVAKQLRDQQIGMRGFRDTPTSLTRVFNRYIPTAAAFGGMCIGALTILADFLGALGSGTGILLAVTIIYQFYEMLVKEQEKATSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRQ0</accession>
    <name>A0A1J1GRQ0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Small nuclear ribonucleoprotein E</fullName>
            <shortName evidence="12">snRNP-E</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Sm protein E</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">SNRPE</name>
        <name evidence="14" type="ORF">PGAL8A_00261200</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 12">Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528020.1">
        <property type="nucleotide sequence ID" value="XM_028671360.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRQ0"/>
    <dbReference type="GeneID" id="39731141"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00261200"/>
    <dbReference type="OMA" id="VPPINCI"/>
    <dbReference type="OrthoDB" id="25620at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005687">
        <property type="term" value="C:U4 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01718">
        <property type="entry name" value="Sm_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000013">
        <property type="entry name" value="Small nuclear ribonucleoprotein E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027078">
        <property type="entry name" value="snRNP-E"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11193">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 12" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8 12" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="9 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 12 14" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7 12" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 12" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="13">
        <location>
            <begin position="16"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00058057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU365053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG95208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="94" mass="11015" checksum="CC3774431F3C2F4E" modified="2017-02-15" version="1">MATTNKKLQKIMTQPINQIFRFFTNKTVVQIWLYDKPDIRIEGKILGFDEYMNMVLDESEEILVKKNSRKQLGKILLKGDTITLIMEAHKGEQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRU1</accession>
    <name>A0A1J1GRU1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00239500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527811.1">
        <property type="nucleotide sequence ID" value="XM_028671128.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730923"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00239500"/>
    <dbReference type="OMA" id="KGNIKHT"/>
    <dbReference type="OrthoDB" id="372719at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="276"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="465"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="509"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="847"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1115"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1213"/>
            <end position="1234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="188"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="509"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="548"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1130"/>
            <end position="1142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1411" mass="161760" checksum="9CECC47A4DA0F26F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRW2</accession>
    <name>A0A1J1GRW2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00257500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527983.1">
        <property type="nucleotide sequence ID" value="XM_028671319.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731103"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00257500"/>
    <dbReference type="OMA" id="KMFISEH"/>
    <dbReference type="OrthoDB" id="272810at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045053">
        <property type="term" value="P:protein retention in Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14376">
        <property type="entry name" value="CUE_AUP1_AMFR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026847">
        <property type="entry name" value="VPS13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16166:SF93">
        <property type="entry name" value="INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16166">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="220"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="853"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1394"/>
            <end position="1428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="2981"/>
            <end position="3006"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="3297"/>
            <end position="3367"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1268"/>
            <end position="1295"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1331"/>
            <end position="1363"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1522"/>
            <end position="1549"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1897"/>
            <end position="1931"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="2358"/>
            <end position="2392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="236"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="853"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="870"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1416"/>
            <end position="1428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="2983"/>
            <end position="2998"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="3297"/>
            <end position="3315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="3316"/>
            <end position="3335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="3345"/>
            <end position="3361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="5072" mass="593900" checksum="66AC1E1C59B85340" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRW8</accession>
    <name>A0A1J1GRW8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Apicoplast calcium binding protein 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ACBP1</name>
        <name evidence="4" type="ORF">PGAL8A_00242000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527835.1">
        <property type="nucleotide sequence ID" value="XM_028671154.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRW8"/>
    <dbReference type="GeneID" id="39730948"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00242000"/>
    <dbReference type="OMA" id="SYDFNYV"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="132"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="90"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="400" mass="47942" checksum="3B43A4A1D1C39D31" modified="2017-02-15" version="1">MKLLKLSWVRHDALISKFVLFASFLFLILLSDSFIKKEYFFNIKIRSSKLCHFLQNNFYKLEKVLLCTSLNNFPLNDWKSLKKGNVMSHEEKVNEETNIIENKIKKKKEEMKEDENSLDLVLDTNNPSLDKNVLEKSKLVFKKLDRNNNNLIDFNEFRTNVEILSKSDDINTNILNYLFQLFDINKDKKLNYTEFLSLNSYDFNYIKLIKILFDADDTVDKSTIYEYLQIYFSEFLENIIEEEKHILIRKNNLVHLLSKNFFKNSRSKWDINEDEKLQMEEFQNFQLSLLIEIDHLSNFLQLDYNLDGKIDIAELLFYLNNDKNVYNKLFTYIKNNKKKEDLFKYIKESLNIDDSLIFNLKVLFYSFDIDNDMLLDLEEYQNQVDTFLILDVTPEIIYAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSL6</accession>
    <name>A0A1J1GSL6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00266600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000036">
        <property type="protein sequence ID" value="CRG95463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528274.1">
        <property type="nucleotide sequence ID" value="XM_028671641.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSL6"/>
    <dbReference type="GeneID" id="39731195"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00266600"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="157"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="217" mass="26123" checksum="99AC9A9B15C7C6B7" modified="2017-02-15" version="1">MKTLTLYSKITTFLLLIWMYQCFYNCDYYKTWTDKNILQTKHELKYERVLTEGDIADENQSKAEGCLEECPSYNKKKKKKNRFQYQNPSHGVTTPSLWESFDKKAKEMDSNLRDHELNIKWNDVSRDNVINLSSKIYQRNIPGEGRQILILSDTKDHSNLKKLLDELKKEIRDNKTEFESMKEMRNNKTESESKKEMRGYMTFYEFMKEKIYNKTEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSN1</accession>
    <name>A0A1J1GSN1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L44, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPL44</name>
        <name evidence="5" type="ORF">PGAL8A_00003700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL42 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528083.1">
        <property type="nucleotide sequence ID" value="XM_028671430.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSN1"/>
    <dbReference type="GeneID" id="39728559"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00003700"/>
    <dbReference type="OMA" id="CKKHTIH"/>
    <dbReference type="OrthoDB" id="2967263at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.80:FF:000001">
        <property type="entry name" value="60S ribosomal protein L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000552">
        <property type="entry name" value="Ribosomal_eL44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053708">
        <property type="entry name" value="Ribosomal_LSU_eL42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10369">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L36A/L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00935">
        <property type="entry name" value="Ribosomal_L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01172">
        <property type="entry name" value="RIBOSOMAL_L44E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="103" mass="12039" checksum="21EA86ED72FBA694" modified="2017-02-15" version="1">MVNVPKTRKTYCSNKCKKHTLHKVSQYKKGKERTSALGRRRYDMKQKGFGGQTKPVFKKKAKTTKKIVLKLECTKCKKKRFLTMKRCKTFEMGADKKKKGAVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSP5</accession>
    <name>A0A1J1GSP5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cysteine-rich protective antigen, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CyRPA</name>
        <name evidence="3" type="ORF">PGAL8A_00177900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000021">
        <property type="protein sequence ID" value="CRG94067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526888.1">
        <property type="nucleotide sequence ID" value="XM_028670103.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSP5"/>
    <dbReference type="GeneID" id="39730306"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00177900"/>
    <dbReference type="OMA" id="ECYLYYT"/>
    <dbReference type="OrthoDB" id="380483at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041396">
        <property type="entry name" value="CyRPA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18638">
        <property type="entry name" value="CyRPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012046031" evidence="1">
        <location>
            <begin position="25"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="Cysteine-rich protective antigen 6 bladed" evidence="2">
        <location>
            <begin position="37"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="354" mass="41591" checksum="E5F7CB2FD62FF405" modified="2017-02-15" version="1">MMFLSGKSFFFLCFIFLLLRVIKSDHVHLLNDEFLAVENPFYCIRESFIYFRNEVYKICIHKGEGMDSKLNIYIQKKRENLWEVQTELFQDSRKTKLPSFFSYVVDEEMIIIFCEITGYEVKRKFDCTRSVSSTGIDFKTEKVVLPYDLMKNKNITFYSSAPFSFTNHKYLLICGIYNSALKSPKQGNFINCAGSNDKGLNWKTKFLFHYDNIEDYTTYFLLKPKIHDNKLGFFFNYVSSSGESGKYIECEHKSNQDFNCKDVDFIKKDKALRDVIKVNDYYITSYANKNSSAVCYLYYSNENSLLLKPRNTGEDYIGCYRGTFMKLDGNKILFMYSSGNGIYNLYTFRPNSYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSQ5</accession>
    <name>A0A1J1GSQ5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Reticulocyte binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00272300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000042">
        <property type="protein sequence ID" value="CRG95523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528332.1">
        <property type="nucleotide sequence ID" value="XM_028671706.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731255"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00272300"/>
    <dbReference type="OMA" id="ANRWRIV"/>
    <dbReference type="OrthoDB" id="385684at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012227309" evidence="3">
        <location>
            <begin position="22"/>
            <end position="2546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="421"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="539"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="847"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1173"/>
            <end position="1404"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1571"/>
            <end position="1633"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1661"/>
            <end position="1698"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1853"/>
            <end position="1901"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2037"/>
            <end position="2064"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="232"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2546" mass="299983" checksum="AB8EA2AAB33520CA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GST0</accession>
    <name>A0A1J1GST0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glideosome associated protein with multiple membrane spans 3, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">GAPM3</name>
        <name evidence="2" type="ORF">PGAL8A_00278700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528398.1">
        <property type="nucleotide sequence ID" value="XM_028671780.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GST0"/>
    <dbReference type="GeneID" id="39731320"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00278700"/>
    <dbReference type="OMA" id="DDACWAR"/>
    <dbReference type="OrthoDB" id="396938at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021691">
        <property type="entry name" value="DUF3273"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11677">
        <property type="entry name" value="DUF3273"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="284" mass="32804" checksum="CF5FF93672E44DB9" modified="2017-02-15" version="1">MWFTTRQDGLDDNCHTNRGPCVQISGFFGTTLRIGFFLEFIALTFLFMAYWSNGGKGLFSYDLRNMKDEYRLDQAFRNSITLWAGVYLIGAIFIMSFQVLLADDTCWARGYRAGSKILRLASFLDTISATLQFIFYLYISKFYTRKWYVHFNEGGSEWVFFIFVRLVHAFSCLLYGLAAYLLEVYHDEGAGDLHAYINGVIFAFAGLTEIFVIFCNSGSFSNLLLWLALAAVSLWSYYFEPEVNHVSPALHETELTNDVEQQVEKFSRYTPYTQEQNQNAYYPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT04</accession>
    <name>A0A1J1GT04_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aldo-keto reductase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00280700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528418.1">
        <property type="nucleotide sequence ID" value="XM_028671802.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT04"/>
    <dbReference type="GeneID" id="39731340"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00280700"/>
    <dbReference type="OMA" id="YNLLHRN"/>
    <dbReference type="OrthoDB" id="2310150at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF4">
        <property type="entry name" value="NAD(P)-LINKED OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="3">
        <location>
            <begin position="352"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="140"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="144"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="162"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="178"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="191"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="202"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="999" mass="118948" checksum="B62AE24B48DCBB63" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT22</accession>
    <name>A0A1J1GT22_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00184000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527269.1">
        <property type="nucleotide sequence ID" value="XM_028670525.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT22"/>
    <dbReference type="GeneID" id="39730367"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00184000"/>
    <dbReference type="OMA" id="YCVSLVF"/>
    <dbReference type="OrthoDB" id="368340at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="79" mass="9560" checksum="82FC0E6150D9C769" modified="2017-02-15" version="1">MSKAVYAKIWMSTRNFQLRRRYGWFKVCSRLSPWLYVWSFFCVSLLFPALNNEHKKLLTFGIWKENDVGYNKCAPQPYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT45</accession>
    <name>A0A1J1GT45_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PIR-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00266500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000035">
        <property type="protein sequence ID" value="CRG95462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528273.1">
        <property type="nucleotide sequence ID" value="XM_028671640.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT45"/>
    <dbReference type="GeneID" id="39731194"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00266500"/>
    <dbReference type="OMA" id="TSSHENF"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="275"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="153"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="210"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="372" mass="41105" checksum="41370E6DFF34E499" modified="2017-02-15" version="1">MIIYIYLLVCIFQYFYSINFEIGKNNLKTELCHRSGRILAEQQRGTSSRRVRSTSSHENFLQIWLKSIEGDFFDQLEKLTKNFTANNAQDFLDWMYQKGGNITKVLNLSSDPEVKSFFNKTLTSWRRVTDDVLLDSALGSYVDSLFKTTNITTNNNGSSSTLPSTSTSLSTPTLSSNLTTSSISTSSPELTISPTAMPSASDLSPTVDLTPTTSDSHIHTTTSSTDDASDLPTVFSTNGMNSTIALTNNSTVLTPTQHGGGLTGATCTGLLCAPAFAALPISVALLGGVFFFVLLYKYTPIGKFLGRDNPKKKKAKKRLNEIPMECINSPKLLKVKKTENTKRSRLHRFLRAFGYDKNFPYIDEDIPSDQVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTA5</accession>
    <name>A0A1J1GTA5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Dynein-associated protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00292600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the inner dynein arm light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528530.1">
        <property type="nucleotide sequence ID" value="XM_028671926.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTA5"/>
    <dbReference type="GeneID" id="39731459"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00292600"/>
    <dbReference type="OMA" id="LKYDNCI"/>
    <dbReference type="OrthoDB" id="273640at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045504">
        <property type="term" value="F:dynein heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019347">
        <property type="entry name" value="Axonemal_dynein_light_chain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13183:SF0">
        <property type="entry name" value="AXONEMAL DYNEIN LIGHT INTERMEDIATE POLYPEPTIDE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13183">
        <property type="entry name" value="AXONEMAL INNER ARM DYNEIN LIGHT CHAIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10211">
        <property type="entry name" value="Ax_dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0243">Dynein</keyword>
    <keyword evidence="3" id="KW-0505">Motor protein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="187"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="257" mass="30900" checksum="3CC77F97A6E449A8" modified="2017-02-15" version="1">MRDYLVKYNKYLKYDISLIIENEDEKNKNLKDEKNMKDKNIVRVIEEIRKNLKSNILYKNDNKNVFFNDPIYQFFPSKCTKEKNVESISYVSRVANEEDTLICLRKIYEVIANMYAENFVIKKEFLDDLLNIFMELCRQVSVMCFQRGFLLKKLFNYNVMLLNQYHKLVKSSLVFNIKKQIKQNEILSNLNNEIEIKRNAINSLKIKIINTEEMIENETINAEKELSEVNMIYQNKIDKLKKNNQRNKDEFTRILQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTG2</accession>
    <name>A0A1J1GTG2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">DNA mismatch repair protein MSH2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00299000</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528586.1">
        <property type="nucleotide sequence ID" value="XM_028671989.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTG2"/>
    <dbReference type="GeneID" id="39731523"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00299000"/>
    <dbReference type="OMA" id="KLYYAIL"/>
    <dbReference type="OrthoDB" id="295033at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032301">
        <property type="term" value="C:MutSalpha complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043570">
        <property type="term" value="P:maintenance of DNA repeat elements"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006312">
        <property type="term" value="P:mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001115">
        <property type="entry name" value="DNA mismatch repair protein MSH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="entry name" value="MutS, connector domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011184">
        <property type="entry name" value="DNA_mismatch_repair_Msh2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007861">
        <property type="entry name" value="DNA_mismatch_repair_MutS_clamp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF35">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MSH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05190">
        <property type="entry name" value="MutS_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005813">
        <property type="entry name" value="MSH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="9">
        <location>
            <begin position="634"/>
            <end position="650"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG95778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="810" mass="94873" checksum="39A77DBB4B7082E6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTL8</accession>
    <name>A0A1J1GTL8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MORN repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00283800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528449.1">
        <property type="nucleotide sequence ID" value="XM_028671836.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTL8"/>
    <dbReference type="GeneID" id="39731371"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00283800"/>
    <dbReference type="OrthoDB" id="392831at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042995">
        <property type="term" value="C:cell projection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048678">
        <property type="term" value="P:response to axon injury"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052315">
        <property type="entry name" value="MORN4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46614">
        <property type="entry name" value="MORN REPEAT-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46614:SF1">
        <property type="entry name" value="MORN REPEAT-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="341"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="554"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="345"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="372"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="572"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="795" mass="94373" checksum="16A29C100E1DAD0D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTL9</accession>
    <name>A0A1J1GTL9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pseudouridine synthase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00410200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pseudouridine synthase RsuA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527216.1">
        <property type="nucleotide sequence ID" value="XM_028670467.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTL9"/>
    <dbReference type="GeneID" id="39732632"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00410200"/>
    <dbReference type="OMA" id="EWINNGW"/>
    <dbReference type="OrthoDB" id="440619at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02870">
        <property type="entry name" value="PseudoU_synth_RsuA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="entry name" value="RNA-binding S4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000748">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB/E/F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018496">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050343">
        <property type="entry name" value="RsuA_PseudoU_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00093">
        <property type="entry name" value="pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47683">
        <property type="entry name" value="PSEUDOURIDINE SYNTHASE FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47683:SF2">
        <property type="entry name" value="RNA-BINDING S4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55174">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01149">
        <property type="entry name" value="PSI_RSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RNA-binding S4" evidence="4">
        <location>
            <begin position="45"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="311" mass="37116" checksum="ED2717C33FA2C997" modified="2017-02-15" version="1">MKFLYSILFYFNKLLCYFLIITSFKSNIFCFDLTITKNKSNEYIIRLNKLISIKKNISRRKSEKFIKDGNVKLNNKIITDPGRHVDITKDSLKICEKKIKIKNIKSLINEYKNNSYKWIVLHKPKGLICTSNDEKNRKSIFSIFPNDLLEKYRFVSVGRLDRNTSGVLLLTNEYEWVNRLTHPKYQRIRTYRIHIEGPVKMNVLKELASGIYLENDSSKKEKKKTQPAFIEIIREENLKIKDQIKKISVLSISVKEGRNRQIRKMFEQINQPIIKIKRTAFENITLKNIHFPKQYRELNQREVTNLKMRKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTN9</accession>
    <name>A0A1J1GTN9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Minichromosome maintenance 8</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">PGAL8A_00310600</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528702.1">
        <property type="nucleotide sequence ID" value="XM_028672117.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTN9"/>
    <dbReference type="GeneID" id="39731639"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00310600"/>
    <dbReference type="OrthoDB" id="422555at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000007">
        <property type="entry name" value="DNA helicase MCM8 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF47">
        <property type="entry name" value="DNA HELICASE MCM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9 14" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="16">
        <location>
            <begin position="576"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="401"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="403"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="17">
        <location>
            <position position="990"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00042306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="CRG95894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="990" mass="114852" checksum="F0753375D4C93519" modified="2017-02-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTS9</accession>
    <name>A0A1J1GTS9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00314700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528742.1">
        <property type="nucleotide sequence ID" value="XM_028672161.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTS9"/>
    <dbReference type="GeneID" id="39731680"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00314700"/>
    <dbReference type="OMA" id="GNKYFMD"/>
    <dbReference type="OrthoDB" id="369669at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013334883" evidence="1">
        <location>
            <begin position="22"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="108" mass="13265" checksum="7A6AE6DB59C43FB1" modified="2017-02-15" version="1" fragment="single">MSKSFAILIFFFFFSFKLTYTLKKENSLIKNENSRFIQINRDMNEPPFSVINVYYTESLLNEDLINEIENNRKMEKDKIRKYFRRNLITNNYFTEYSKKQKEQMESLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTV1</accession>
    <name>A0A1J1GTV1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">YrhK domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00309100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528687.1">
        <property type="nucleotide sequence ID" value="XM_028672101.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTV1"/>
    <dbReference type="GeneID" id="39731624"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00309100"/>
    <dbReference type="OMA" id="WFDYIIY"/>
    <dbReference type="OrthoDB" id="369339at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025424">
        <property type="entry name" value="YrhK_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14145">
        <property type="entry name" value="YrhK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="170"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="233"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="YrhK" evidence="3">
        <location>
            <begin position="90"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="YrhK" evidence="3">
        <location>
            <begin position="210"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="263" mass="30365" checksum="A1B9FEF4FB022C82" modified="2017-02-15" version="1">MHKQRSINKADICEEVYPTLHKYRKGNSQVGTFLKKEDNSALKNSPQIYNDSKKKKSPSSNKSKKLHKKYENISKIKMENFLKCPMAYHTNFLGTILFVIGSVFFLFSNLYIYGCLIFAFACVLCFYSNLVGATNIKLKRKNEFYGFICYIIGCLIFIIGSIYSCFKDDYYAVGSFIIGSLFFLIGAFLFFFTINLKKIKCVNYKILIVFISNFIGGVLFTVGSIFFLYSNLYIEACYCFIIGSVLFTLATWFDYIIYINDTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUL8</accession>
    <name>A0A1J1GUL8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00213400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527552.1">
        <property type="nucleotide sequence ID" value="XM_028670839.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730661"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00213400"/>
    <dbReference type="OMA" id="INSKCIG"/>
    <dbReference type="OrthoDB" id="376263at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1007"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1163"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1247"/>
            <end position="1270"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="38"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1296" mass="155998" checksum="E49D0C0B46ACB09E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUM6</accession>
    <name>A0A1J1GUM6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00339900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528986.1">
        <property type="nucleotide sequence ID" value="XM_028672434.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731929"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00339900"/>
    <dbReference type="OMA" id="EEWYSIA"/>
    <dbReference type="OrthoDB" id="392230at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005033">
        <property type="entry name" value="YEATS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23195">
        <property type="entry name" value="YEATS DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="523"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="622"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="666"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3570"/>
            <end position="3597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3799"/>
            <end position="3845"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3921"/>
            <end position="3944"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="4492"/>
            <end position="4511"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2523"/>
            <end position="2550"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3634"/>
            <end position="3671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="523"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="542"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="552"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="670"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="720"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="731"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="770"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="785"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="841"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="3570"/>
            <end position="3581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="3585"/>
            <end position="3597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="3810"/>
            <end position="3819"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="5442" mass="647515" checksum="31E3C824FA974308" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUR0</accession>
    <name>A0A1J1GUR0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ancestral coatomer element 1 Sec16/Sec31 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00346500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529052.1">
        <property type="nucleotide sequence ID" value="XM_028672506.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731995"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00346500"/>
    <dbReference type="OMA" id="YEYNNVN"/>
    <dbReference type="OrthoDB" id="8918678at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="190"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="308"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="433"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="833"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1440"/>
            <end position="1486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1666" mass="199749" checksum="6A5020634F121936" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV99</accession>
    <name>A0A1J1GV99_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">subtilisin</fullName>
            <ecNumber evidence="8">3.4.21.62</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">SUB2</name>
        <name evidence="16" type="ORF">PGAL8A_00364500</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>Hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyzes peptide amides.</text>
            <dbReference type="EC" id="3.4.21.62"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 9 10">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.62" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529226.1">
        <property type="nucleotide sequence ID" value="XM_028672700.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV99"/>
    <dbReference type="SMR" id="A0A1J1GV99"/>
    <dbReference type="GeneID" id="39732175"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00364500"/>
    <dbReference type="OMA" id="EYSTWNL"/>
    <dbReference type="OrthoDB" id="371436at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051048">
        <property type="entry name" value="Peptidase_S8/S53_subtilisin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040935">
        <property type="entry name" value="Pro_sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43399:SF4">
        <property type="entry name" value="CELL WALL-ASSOCIATED PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43399">
        <property type="entry name" value="SUBTILISIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18513">
        <property type="entry name" value="Pro_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 9 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 9 10" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 10" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0865">Zymogen</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="964"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="domain" description="Subtilisin-like protease 2 prodomain" evidence="15">
        <location>
            <begin position="382"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="14">
        <location>
            <begin position="573"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="261"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="311"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="212"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="1018"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="261"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="284"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="330"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="345"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="9">
        <location>
            <position position="581"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="9">
        <location>
            <position position="624"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="9">
        <location>
            <position position="787"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF18513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="CRG96421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1091" mass="125692" checksum="720C763F1FAAD86A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVB3</accession>
    <name>A0A1J1GVB3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Major facilitator superfamily protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00362600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529207.1">
        <property type="nucleotide sequence ID" value="XM_028672679.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVB3"/>
    <dbReference type="GeneID" id="39732156"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00362600"/>
    <dbReference type="OMA" id="PYYNTEE"/>
    <dbReference type="OrthoDB" id="331466at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044770">
        <property type="entry name" value="MFS_spinster-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23505:SF9">
        <property type="entry name" value="PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23505">
        <property type="entry name" value="SPINSTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="464"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="501"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="534"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="557"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="591"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="621"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="753"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="790"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="830"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="858"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="892"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="928"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="468"/>
            <end position="949"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG96402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="949" mass="112006" checksum="FE432BE89E384133" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVB8</accession>
    <name>A0A1J1GVB8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00369600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
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            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529276.1">
        <property type="nucleotide sequence ID" value="XM_028672756.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732226"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00369600"/>
    <dbReference type="OrthoDB" id="445556at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052758">
        <property type="entry name" value="SRC_co-chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44200">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44200:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="776"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="292"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="864"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1102"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1154"/>
            <end position="1277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1928"/>
            <end position="1954"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="182"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="958"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1878"/>
            <end position="1920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="292"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="320"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="864"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1105"/>
            <end position="1116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1154"/>
            <end position="1165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1173"/>
            <end position="1213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1214"/>
            <end position="1225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1240"/>
            <end position="1277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1931"/>
            <end position="1954"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1954" mass="232573" checksum="136B6DE99795C9FD" modified="2017-02-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVH1</accession>
    <name>A0A1J1GVH1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CID domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00368300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529263.1">
        <property type="nucleotide sequence ID" value="XM_028672740.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVH1"/>
    <dbReference type="GeneID" id="39732213"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00368300"/>
    <dbReference type="OMA" id="RNIPFNV"/>
    <dbReference type="OrthoDB" id="338650at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006569">
        <property type="entry name" value="CID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04818">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51391">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CID" evidence="3">
        <location>
            <begin position="470"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="133"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="56"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="35"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="94"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="133"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="734" mass="86603" checksum="78FF815AB9AA29D6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVJ4</accession>
    <name>A0A1J1GVJ4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cochaperone prefoldin complex subunit, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00355000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prefoldin subunit alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529137.1">
        <property type="nucleotide sequence ID" value="XM_028672601.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVJ4"/>
    <dbReference type="GeneID" id="39732080"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00355000"/>
    <dbReference type="OMA" id="NYYVQRN"/>
    <dbReference type="OrthoDB" id="10267474at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990113">
        <property type="term" value="P:RNA polymerase I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990114">
        <property type="term" value="P:RNA polymerase II core complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990115">
        <property type="term" value="P:RNA polymerase III assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23157">
        <property type="entry name" value="Prefoldin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011599">
        <property type="entry name" value="PFD_alpha_archaea"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004127">
        <property type="entry name" value="Prefoldin_subunit_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12674">
        <property type="entry name" value="PREFOLDIN SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12674:SF2">
        <property type="entry name" value="PREFOLDIN SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02996">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="134"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="205"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="268" mass="31600" checksum="7D43EB9FA013CD67" modified="2017-02-15" version="1">MACDLEKIEENEREKPNVVIQLNTLGLEELVSLTLKLEEEWKLIKKNYTILESAVVTYDKCKNCVEQLNPSKYEAKNFNIFMNELERSELIKLCGKEPDDKNKSVDIKDSQEKNKLENIDNLIDKIKISNKEEEKEIEKEKEEKEKENEKENEKEKEKEKKQQTLDVHIPLTSLVYIPGKIVDTENFLIRMGTNYYVQRNSEQTIEYFNDKVKRLNEQIKKLKVTLIEKKNEIDLCKNYIQIKREQQINNLNTNTQPSSLNVNPSVNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVQ7</accession>
    <name>A0A1J1GVQ7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CLU central domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00421200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529436.1">
        <property type="nucleotide sequence ID" value="XM_028672933.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732744"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00421200"/>
    <dbReference type="OMA" id="VIIQEYT"/>
    <dbReference type="OrthoDB" id="1414216at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033646">
        <property type="entry name" value="CLU-central"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20916">
        <property type="entry name" value="CYSTEINE AND GLYCINE-RICH PROTEIN 2 BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20916:SF18">
        <property type="entry name" value="IPT_TIG DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12807">
        <property type="entry name" value="eIF3_p135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CLU central" evidence="3">
        <location>
            <begin position="614"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1836"/>
            <end position="1867"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1663"/>
            <end position="1720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1843"/>
            <end position="1857"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1922" mass="231027" checksum="7945FCE083A20154" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVQ9</accession>
    <name>A0A1J1GVQ9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">5'-3' exoribonuclease</fullName>
            <ecNumber evidence="6">3.1.13.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00422200</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Possesses 5'-&gt;3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.-" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529446.1">
        <property type="nucleotide sequence ID" value="XM_028672944.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVQ9"/>
    <dbReference type="GeneID" id="39732754"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00422200"/>
    <dbReference type="OMA" id="ITHDMVV"/>
    <dbReference type="OrthoDB" id="372487at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004534">
        <property type="term" value="F:5'-3' RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18673">
        <property type="entry name" value="PIN_XRN1-2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.1050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12390">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027073">
        <property type="entry name" value="5_3_exoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041412">
        <property type="entry name" value="Xrn1_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004859">
        <property type="entry name" value="Xrn1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017151">
        <property type="entry name" value="Xrn2/3/4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341:SF7">
        <property type="entry name" value="5'-3' EXORIBONUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341">
        <property type="entry name" value="5'-&gt;3' EXORIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17846">
        <property type="entry name" value="XRN_M"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03159">
        <property type="entry name" value="XRN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037239">
        <property type="entry name" value="Exonuclease_Xrn2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3 6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Xrn1 N-terminal" evidence="9">
        <location>
            <begin position="1"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="Xrn1 helical" evidence="10">
        <location>
            <begin position="361"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="Xrn1 helical" evidence="10">
        <location>
            <begin position="586"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1162"/>
            <end position="1183"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="857"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1162"/>
            <end position="1179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR037239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG96642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1218" mass="144056" checksum="43855964C12FA83E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVS2</accession>
    <name>A0A1J1GVS2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SET domain protein, putative</fullName>
            <ecNumber evidence="2">2.1.1.43</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">SET4</name>
        <name evidence="2" type="ORF">PGAL8A_00422800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.43" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529452.1">
        <property type="nucleotide sequence ID" value="XM_028672950.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVS2"/>
    <dbReference type="GeneID" id="39732760"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00422800"/>
    <dbReference type="OMA" id="PHSIHTD"/>
    <dbReference type="OrthoDB" id="1028014at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050869">
        <property type="entry name" value="H3K4_H4K5_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12197:SF292">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="271"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1059" mass="125713" checksum="E1EBA54BE429FF00" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVS3</accession>
    <name>A0A1J1GVS3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00015500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528197.1">
        <property type="nucleotide sequence ID" value="XM_028671557.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVS3"/>
    <dbReference type="GeneID" id="39728677"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00015500"/>
    <dbReference type="OrthoDB" id="385277at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="497" mass="58389" checksum="E860DEF558CAABB4" modified="2017-02-15" version="1">MRNKNMNLNIIIKASFPRLNSEKKKKKKNAKISSKPKSEKENSDKKKIKNIKKKENFLSNKLIISTSLLSYDKRKNIKLFNDSFNKKKVTSKKSFPEKDKYRKIYTKRQFSNKSNNLNKFSAKSILNINIPKNSKKKNIGNILGSKLIKSSIKIVDTTNKKRNFSSNLQKNTQKKNKYISSDLKIILNKRNYKLKKGVAQLEKPLKKKKNKIKNFITLKKNLNTMEDKENQGDNSHNGNEKKEVDDQIELKEDKEMNIKNDKEVKDTKDQEMNMKKDEKMDTIKNEKMDTIKNEKMNTTKDEKMNTTKNEKMDTTKDQETNVEKNKNVIAQDVEKNNKEKKEKLIQDKISKNYALNYSNSCIHKSENLEYYFSEGTYEPSNDIFNENYQKVTNTLLPGYTITACEDIYQVNKDDTISDIRDLKKSGEYIYKSYFPTHKFIPHLNNNPVKEAYYLRNHEVLYNYLYTSSDLTRGSLHEQSNMVVAYPYGVPFIDIKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVS8</accession>
    <name>A0A1J1GVS8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00252800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527936.1">
        <property type="nucleotide sequence ID" value="XM_028671267.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVS8"/>
    <dbReference type="GeneID" id="39731056"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00252800"/>
    <dbReference type="OMA" id="NKECNYK"/>
    <dbReference type="OrthoDB" id="377245at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="50"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="105" mass="12902" checksum="B14E8C11CCDBD999" modified="2017-02-15" version="1">MDMYPLYYSKLNNNVVKELNYLSKTRQMNKINEEEISFNKECNYKLFFFIVQLQQKLKDIEKENEKLKYLLKKYNRESIENDNKIIKRVLLVISSIIFIIIFFLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVU9</accession>
    <name>A0A1J1GVU9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00367700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529257.1">
        <property type="nucleotide sequence ID" value="XM_028672734.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVU9"/>
    <dbReference type="GeneID" id="39732207"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00367700"/>
    <dbReference type="OMA" id="FCEKKHV"/>
    <dbReference type="OrthoDB" id="387476at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="399" mass="47477" checksum="346DE66ECB65F0D1" modified="2017-02-15" version="1">MDTTNEVCKIESILDKILPEKDLNLVTLKSVRKDVADHLNVDESYFSENKEKKDLLKKILKEKILKLYNQQQNEEADEKKEKDKDEDEEIKKYTLKNNIKKKKVIESNEESCEDIKGDSRESEELYEDESESDKSVKVKKKKKREINSDENKPLKKKRKEEIDSGDDLTKKKKKRSFSNNSKQKNAHTTKKEKLRKIVLDLKIGPTIFKDLNKENEEEYNKKLEQRIIEFCEKKQICSEQNRLPNPAEIHEYRKKKKLKEELDGIDPSNIIDSTTRPRRRNQNIYVSQKFSESDEEDDEDDEENEDDDEAVVEGEEDETVDESLTEKGKNLKKKNKRKKENNDEQDEEEEDEEEDEEDEEEDEEEDEDEEEEEEKEEDDEEEDDDDEEEVEEEGDEEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVZ9</accession>
    <name>A0A1J1GVZ9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein uL3c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00431000</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the universal ribosomal protein uL3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529534.1">
        <property type="nucleotide sequence ID" value="XM_028673041.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVZ9"/>
    <dbReference type="GeneID" id="39732842"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00431000"/>
    <dbReference type="OMA" id="CTICEFM"/>
    <dbReference type="OrthoDB" id="274683at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000004">
        <property type="entry name" value="50S ribosomal protein L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000597">
        <property type="entry name" value="Ribosomal_uL3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019927">
        <property type="entry name" value="Ribosomal_uL3_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019926">
        <property type="entry name" value="Ribosomal_uL3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03625">
        <property type="entry name" value="L3_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11229">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11229:SF16">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00297">
        <property type="entry name" value="Ribosomal_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00474">
        <property type="entry name" value="RIBOSOMAL_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 8 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG96730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="323" mass="37163" checksum="DDBEC29EB6F5C3C1" modified="2017-02-15" version="1">MKKWKYIMHCYFIYAILIISIFFQISFNFKILSDLNCSEKNLSDRNGNHLRYYNGLLKAKNIKSKRNFQINMIKKVVIGRDPFDPQDHLKDIPYKDELDRIQIKGKKIEMRSIFSPNGKLIPATLIEIMPNVIYRFLDFGKAAIAYGKPLDESRWILKPELGQISKVGCNFKNTCSLILTPPQNFVLGQIIDVSYLYNYKYVNVRGLTKGKGFCGVIKRWGFRRGPMTHGSSHHRKPGSIGASTHIGRVLKGKKMPGKDGNKFRTMINLKLLGLNLERNEILVSGCIPGNRNSYVTVTATKDNKVSKYKYILDLLYKQEKNIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW46</accession>
    <name>A0A1J1GW46_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00065800</name>
        <name evidence="2" type="ORF">PGAL8A_00272400</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">8A</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="CVMV01000043">
        <property type="protein sequence ID" value="CRG95524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CVMV01000151">
        <property type="protein sequence ID" value="CRG98221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028531018.1">
        <property type="nucleotide sequence ID" value="XM_028674691.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW46"/>
    <dbReference type="GeneID" id="39729183"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00065800"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00272400"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="135" mass="15602" checksum="220B23EE930AF701" modified="2017-02-15" version="1">MKQLFAKLNETLKNNSETNSNLSESYNNNNSNSHNYIDWNILAIILSIVLIIMFSTVINTCRLRQRAIHDNLMLEVESVDSGYADIEYEDIDEEINEGARILDVDDSVERRVNERVTVNVYAQVDSEEEVVVRIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWG9</accession>
    <name>A0A1J1GWG9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Spindle and centriole-associated protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00439600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529618.1">
        <property type="nucleotide sequence ID" value="XM_028673135.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWG9"/>
    <dbReference type="GeneID" id="39732929"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00439600"/>
    <dbReference type="OMA" id="CNEDDNI"/>
    <dbReference type="OrthoDB" id="372463at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1114" mass="132714" checksum="0B414B47B3E2FEED" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWJ3</accession>
    <name>A0A1J1GWJ3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fam-c protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00421100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529435.1">
        <property type="nucleotide sequence ID" value="XM_028672931.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWJ3"/>
    <dbReference type="GeneID" id="39732743"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00421100"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009618940" description="Fam-c protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="329" mass="39032" checksum="EDD4C161932F5EE2" modified="2017-02-15" version="1">MKKINKIVFLIFVSFFIIDQKFSEGFLSDSKDFYDINKSSSSRNISKYGQLRKEKEDKNNLRKNNNASDPCDFEICFEIKKEEQIGVSDKCSRKKCYLHKATLIKNKSVTNLEPHELYGEVENSDISKRWRDGNFSNKKNDYKFEGNNNSDKETGISEENGGTDDDEHGQSWEEFNFDSWDPSNNEYKHNSNSNSNTNSNSNYFLHKFNSSPVYNKSDKLNEVHLMKEKYCTRFTNSDEKNNKEISIYDNIFEMHHKPKCHNYYELKCSCFDESGKAKTEDFVIYINPIYKSKKEEEEIKEHEKSKSNYYEKNIVFMNEIINKLRYYNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWQ5</accession>
    <name>A0A1J1GWQ5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Transcription elongation factor 1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00427500</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the ELOF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529499.1">
        <property type="nucleotide sequence ID" value="XM_028673003.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWQ5"/>
    <dbReference type="GeneID" id="39732807"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00427500"/>
    <dbReference type="OMA" id="PFCNHKQ"/>
    <dbReference type="OrthoDB" id="445983at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008023">
        <property type="term" value="C:transcription elongation factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.190:FF:000001">
        <property type="entry name" value="Transcription elongation factor 1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007808">
        <property type="entry name" value="Elf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038567">
        <property type="entry name" value="T_Elf1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20934">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20934:SF0">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05129">
        <property type="entry name" value="Zn_ribbon_Elf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 10" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6 10" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 10" id="KW-0863">Zinc-finger</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG96695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="111" mass="12933" checksum="1E3AA0EAB158393C" modified="2017-02-15" version="1">MGRSKVRKIKPKKKKPIKLETQFNCPFCSYKKSIDIKMHRSKGIGELICLKCGVKYVNQITNLDECIDVYSEWVDKCLDVNKKGCNEIYFNEELESYNNFEDKAIIDNTPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWZ1</accession>
    <name>A0A1J1GWZ1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00453600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529759.1">
        <property type="nucleotide sequence ID" value="XM_028673291.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWZ1"/>
    <dbReference type="GeneID" id="39733069"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00453600"/>
    <dbReference type="OMA" id="EQFLFFW"/>
    <dbReference type="OrthoDB" id="371853at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="961" mass="117099" checksum="5AEE415B31D6BF17" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX11</accession>
    <name>A0A1J1GX11_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Aspartyl protease, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00456000</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529783.1">
        <property type="nucleotide sequence ID" value="XM_028673319.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX11"/>
    <dbReference type="GeneID" id="39733093"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00456000"/>
    <dbReference type="OMA" id="NDYIIHE"/>
    <dbReference type="OrthoDB" id="2747330at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47965:SF12">
        <property type="entry name" value="ASPARTIC PROTEINASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47965">
        <property type="entry name" value="ASPARTYL PROTEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 10" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013176136" evidence="8">
        <location>
            <begin position="23"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="594"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="9">
        <location>
            <begin position="142"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG96980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="616" mass="72490" checksum="C48A294C220196A1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX22</accession>
    <name>A0A1J1GX22_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Calmodulin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">CAM</name>
        <name evidence="10" type="ORF">PGAL8A_00305700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the calmodulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528653.1">
        <property type="nucleotide sequence ID" value="XM_028672062.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX22"/>
    <dbReference type="SMR" id="A0A1J1GX22"/>
    <dbReference type="GeneID" id="39731590"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00305700"/>
    <dbReference type="OMA" id="ARKMKEC"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000042">
        <property type="entry name" value="Calmodulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000398">
        <property type="entry name" value="Calmodulin-like protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF0">
        <property type="entry name" value="CALMODULIN LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00450">
        <property type="entry name" value="RECOVERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0007">Acetylation</keyword>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="9">
        <location>
            <begin position="8"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="9">
        <location>
            <begin position="44"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="9">
        <location>
            <begin position="81"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="9">
        <location>
            <begin position="117"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG95845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="149" mass="16949" checksum="319C43FCE06EC173" modified="2017-02-15" version="1">MADKLTEEQISEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEIDTDGNGTIDFPEFLTLMARKMKDTDTEEELIEAFRVFDRDGDGYISADELRHVMTNLGEKLTNEEVDEMIREADIDGDGQINYEEFVKMMIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX80</accession>
    <name>A0A1J1GX80_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00463200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529855.1">
        <property type="nucleotide sequence ID" value="XM_028673398.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX80"/>
    <dbReference type="GeneID" id="39733165"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00463200"/>
    <dbReference type="OMA" id="CINLIIE"/>
    <dbReference type="OrthoDB" id="329761at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="355" mass="43028" checksum="60B24B8973D9D0C5" modified="2017-02-15" version="1">MSKPKILISQIKNITDIKTYNLKGIESSKKKIFGYVENLPGEKNWLKPLIGKSMQNYYFPSKYLHLDFNLKEYLRMQTVRFKKKDIDDSLIKLQKCINLIIENKVLIDNFLSKISKELFLENQSLKDFYALYLTIFPYDKYSHNLSFNISELNIPNERFNWFNFNNENINKFKNKQNLDHSNISTDENLKENKLHNLANTKDKNKLINDENYKRIIFTKTKNDIQFKKIICREKKENEKEKEDKIYYLNCNVNLGLEEPIENKKEIEEKEQSKHLFYKLINENENIKKTLLIRNRFIDPLYLRRRYSYIDKLTKKKIKKEKYKTYRKHFIQHADEKKIWPDNKGLLNKIYPNPYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXA4</accession>
    <name>A0A1J1GXA4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Mitochondrial ACP, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PGAL8A_00313800</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acyl carrier protein (ACP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528733.1">
        <property type="nucleotide sequence ID" value="XM_028672151.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXA4"/>
    <dbReference type="GeneID" id="39731671"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00313800"/>
    <dbReference type="OMA" id="NGMTYRC"/>
    <dbReference type="OrthoDB" id="448946at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000035">
        <property type="term" value="F:acyl binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000036">
        <property type="term" value="F:acyl carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003231">
        <property type="entry name" value="ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20863">
        <property type="entry name" value="ACYL CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20863:SF28">
        <property type="entry name" value="ACYL CARRIER PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14573">
        <property type="entry name" value="PP-binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="12" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Carrier" evidence="13">
        <location>
            <begin position="69"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG95925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="152" mass="18292" checksum="19C64243C8EE2313" modified="2017-02-15" version="1">MKKKLIQKIFFNKNINFSYISRRGYFKTLLQNDMKHKWNGFCKNNYIKSEQFVNFSTEKKSELNFLSKEQIEEKVITVLKKYLPNDAEIKYEEELEKNKTKDNRAWDFLDTVEFLIDIESEFNITIPDETADNIKTLQELIDYLVQLNTKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXF3</accession>
    <name>A0A1J1GXF3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phospholipid scramblase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00482000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the phospholipid scramblase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530044.1">
        <property type="nucleotide sequence ID" value="XM_028673608.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXF3"/>
    <dbReference type="GeneID" id="39733353"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00482000"/>
    <dbReference type="OMA" id="NPNMNYP"/>
    <dbReference type="OrthoDB" id="444338at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017128">
        <property type="term" value="F:phospholipid scramblase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005552">
        <property type="entry name" value="Scramblase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23248:SF9">
        <property type="entry name" value="PHOSPHOLIPID SCRAMBLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23248">
        <property type="entry name" value="PHOSPHOLIPID SCRAMBLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03803">
        <property type="entry name" value="Scramblase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="295" mass="34276" checksum="6409DB6E8499233E" modified="2017-02-15" version="1">MDHSMNMPVNQTIYGNNMINKVADNQFNQPNTNNNYQNPNMNNLNHVNPMPPPQQQMHMFSNDWKSVIASIKSCKIQQVFNNKEFVADFFIGINLDFSNKYLILDASNNVTKFVAIENSHFANRNCLPKICIPVEMKILRQGKELNMPDLLVEKDCSCTICCLNRPTIKMYDFSNNNNKELIGIIKSPFSCCSYKFDLFDTSNNKIIYMDDTCCQLSILCPLPCGACKYSNFYLHDAKTKEKVAHLIKEVPFLQLVKKDIDNYVMNFEQVVNPEWKMMVLAFALFLDYIYYDYKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXL6</accession>
    <name>A0A1J1GXL6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00324200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000051">
        <property type="protein sequence ID" value="CRG96029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528837.1">
        <property type="nucleotide sequence ID" value="XM_028672268.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXL6"/>
    <dbReference type="GeneID" id="39731775"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00324200"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="324" mass="38606" checksum="E069263EA051C317" modified="2017-02-15" version="1">MALLFNEGCENFEGDSATCRMNICSIKQNKFEKSLCLLEDELVKVYRSLNNVSNDISRNIFKYESYGPYRHSRIIILSDNNQDGIVFLYEYNIYNRYYPTKTYLCRLRNINQTAALCESLDIYYLGKRLSFNSYDVISEKNDLPLKHLKNPNHKIVKLKYKDLFIKEHSCHHIKTRYISHHSCMYAICEKKKEEYMLCSDANYSGKLIYLFSYWPEKSKKFIYLPEGCLKRDSNLACISYFCETNAKDKFFPCEHKEISAIKDIMPDAERSEVMPIKQQIVHHEDNVSASALFAMTLMPFLILFVFFWCYIYKNFKKRRRRKIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXL7</accession>
    <name>A0A1J1GXL7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00461800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529841.1">
        <property type="nucleotide sequence ID" value="XM_028673383.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXL7"/>
    <dbReference type="GeneID" id="39733151"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00461800"/>
    <dbReference type="OMA" id="HHWDVKS"/>
    <dbReference type="OrthoDB" id="16717at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031124">
        <property type="term" value="P:mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045245">
        <property type="entry name" value="Pfs2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22836:SF0">
        <property type="entry name" value="PRE-MRNA 3' END PROCESSING PROTEIN WDR33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22836">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="213"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="255"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="468" mass="53996" checksum="5DD245DD6A274A97" modified="2017-02-15" version="1">MFNEEQNVNNYYPSKLGIDRPAVDFNSSICNFLKNDIYKRQFDRRLYVSHPIFMRRVKPLFCYSNMIDRFDGVLSHLAYTCLNKSKGMIVSLKWFNDGKRLLTGTQLSELAIWNGVYFNFEDMKRIPIGGGSVSCLEWSKNDNLFAGNSLGQIVILSSALNLLDNYAFEGLTKNVLDISLSCCNTKLAGCADTCNPIIWDIKTRKIIKHLKCKNIDTNNISCLSWNPINDIVASGNRTQTISFWDIRINKPIISINAHKANVNKIKWNYNGVYLLSCSKDSLIKLWDIRNFKLLYYYKNDNIYNNRYGLNYEPTYIVWNPIQNHIFASSDNKGYIKFYSTNDNKCIQTISSAHGYDKPCSITLLDWNPLGHILTSFGEDKLLKFWSASSCDSVIAKEIDAKMLININKNGSFPNSRYINDENMLDVSSNQSICDSEEGHYKKNKLNNNYYKKISKKINKKKKKHLFQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXN3</accession>
    <name>A0A1J1GXN3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">40S ribosomal protein S17, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00463400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529857.1">
        <property type="nucleotide sequence ID" value="XM_028673401.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXN3"/>
    <dbReference type="GeneID" id="39733167"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00463400"/>
    <dbReference type="OMA" id="MKRIQQG"/>
    <dbReference type="OrthoDB" id="1727351at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.60.20:FF:000001">
        <property type="entry name" value="40S ribosomal protein S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.60.20">
        <property type="entry name" value="Ribosomal protein S17e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00511">
        <property type="entry name" value="Ribosomal_eS17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001210">
        <property type="entry name" value="Ribosomal_eS17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018273">
        <property type="entry name" value="Ribosomal_eS17_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036401">
        <property type="entry name" value="Ribosomal_eS17_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002242">
        <property type="entry name" value="PRK01151.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10732">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10732:SF0">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00833">
        <property type="entry name" value="Ribosomal_S17e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116820">
        <property type="entry name" value="Rps17e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00712">
        <property type="entry name" value="RIBOSOMAL_S17E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="137" mass="16036" checksum="6AF87A99F67CE0C8" modified="2017-02-15" version="1">MGRVRTKTVKRAARQIVEKYYAKLTLDFQINKKITEEVAIIPSKRMKNKVAGFVTHLMKRIQKGPVRGISLKLQEEERERRLDFVPEKSQIDVNVIYVEPDTVRMIKSLGINISNMKVHNPMINANQQKQNRMNNQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXP1</accession>
    <name>A0A1J1GXP1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Vacuolar-sorting protein SNF7, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00464200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529865.1">
        <property type="nucleotide sequence ID" value="XM_028673409.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXP1"/>
    <dbReference type="GeneID" id="39733175"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00464200"/>
    <dbReference type="OMA" id="DKIDDMM"/>
    <dbReference type="OrthoDB" id="5592979at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009898">
        <property type="term" value="C:cytoplasmic side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000815">
        <property type="term" value="C:ESCRT III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005771">
        <property type="term" value="C:multivesicular body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032511">
        <property type="term" value="P:late endosome to vacuole transport via multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006900">
        <property type="term" value="P:vesicle budding from membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1060">
        <property type="entry name" value="ESAT-6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005024">
        <property type="entry name" value="Snf7_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22761">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22761:SF10">
        <property type="entry name" value="GH13992P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03357">
        <property type="entry name" value="Snf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0967">Endosome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="35"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="193"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="227" mass="26800" checksum="2E5BDEBF53B70E52" modified="2017-02-15" version="1">MRFWFSKKKNSSECINNKKNNDEIYKAVLKNREAIDALEKKQVQVEKKIKQMEIEAKQKVDQNQMNNAKILLKRKKLYEQELENILNNRLTLEDNMINLENMHLHKIAVNALSYSANTHKKFNNEINTQKVEKIIDIIQENKDIQEEVNQALNFNLINNVDDDEIDKELNLLKEQSMEEKLSVEVNKIPEIPKDEEKVNFTNIEKEVSKVKEESDDEELKELIGEMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXQ3</accession>
    <name>A0A1J1GXQ3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00328500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000056">
        <property type="protein sequence ID" value="CRG96072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528877.1">
        <property type="nucleotide sequence ID" value="XM_028672313.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXQ3"/>
    <dbReference type="GeneID" id="39731815"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00328500"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="96" mass="11086" checksum="536E6BAE368D89D0" modified="2017-02-15" version="1">MTYNQSNTTAAPAVSLNSTLENNTSNSTDNNYNPTYTNRILFIIFFIIYVIVKFYTGRFSQYAQHRRNGNNHFDLISIDSGYFENIPEGEQEENVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXR8</accession>
    <name>A0A1J1GXR8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Endoplasmic reticulum transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00301200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528608.1">
        <property type="nucleotide sequence ID" value="XM_028672013.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXR8"/>
    <dbReference type="GeneID" id="39731545"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00301200"/>
    <dbReference type="OrthoDB" id="376949at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="206" mass="24577" checksum="DAE425B470D97F04" modified="2017-02-15" version="1">MKDIAFFFLPGGIILSIFLLSGVAMLQSLAISLQKKSINFQIQSHKINISISSIISLYSLLRLSYTILELNKYNNEKVNFENINSLNLNRSYLKKMRLQRNFWILLLCSITWIFYIRFTYLLKYYREKVKKSDQEFEKILEGKKFRDKKLENKEELENKDELKSENEVLTNEDESNEEKEENVDDKVKSSILVDKNKKKVELRQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY25</accession>
    <name>A0A1J1GY25_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DnaJ protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00503300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530261.1">
        <property type="nucleotide sequence ID" value="XM_028673849.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY25"/>
    <dbReference type="GeneID" id="39733566"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00503300"/>
    <dbReference type="OMA" id="FEIFDIH"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46620">
        <property type="entry name" value="J DOMAIN-CONTAINING PROTEIN SPF31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46620:SF1">
        <property type="entry name" value="J DOMAIN-CONTAINING PROTEIN SPF31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="166"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="386" mass="46038" checksum="066F9D290287E7AC" modified="2017-02-15" version="1">MDEHKDAEISQKESTTESGNNSKNAINEKENNYDKINNFNDLNGGEECQVLNNDVNENINNKENKEMDNFIEDKVDYNTNDNNEKSLNNNENSNNLMGETVNNVSNNNKSNNNTIDENEINDLFDDFLKDIENITSNNNSEQKEKKFNKGDAEKEISRILANKNSSPFEIFDIHEDISVEVIKSKYRKLSILIHPDKCKIEKANEAFNILTRAYEELKKDSIKEQYKSVYETAKKNIIKKLNLKKKKNEINEYLNKAYEEYEITKEIQQLINEECEHLMKVQREKIEYAQKCKLANMKYVQEKEEEKLKEDLKKEEERKLWIEGRDERVNSWKHYKNECLKNEKEFHLFKNINRKKEERTEEEKEKLKKISINNMENTIYKKRRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY28</accession>
    <name>A0A1J1GY28_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">UDP-galactose transporter, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00340200</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528989.1">
        <property type="nucleotide sequence ID" value="XM_028672437.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY28"/>
    <dbReference type="GeneID" id="39731932"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00340200"/>
    <dbReference type="OMA" id="CGAIGQV"/>
    <dbReference type="OrthoDB" id="1601at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005459">
        <property type="term" value="F:UDP-galactose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005460">
        <property type="term" value="F:UDP-glucose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013657">
        <property type="entry name" value="SCL35B1-4/HUT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778:SF10">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08449">
        <property type="entry name" value="UAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="59"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="190"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="313"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG96184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="344" mass="39755" checksum="61FFAD0C08D0984C" modified="2017-02-15" version="1">MVRTRRNNVMNSQKSFKEPSSFYNFLNGVFCICGIYFFFIIFGYYQEKLPNLGKGEEKFYYNIFLICVLCLSNCICSLTAIFIKSKLQNNKFINDLKNNVDTYFIKQIMLISITYSVAMIATNYSLSHVNFPTQVLVKSGKMIPIVVGGYLFFGKKYPYYDYIAVFLITSSLVIFNLLKTKSAKEIHQTTFGIFLLCISLFCDGLTGPRQDKLLSKYNINSINLMFYVNSFAFAFNLIASLIIEGLKPYYFLSKYTDSYYYILAFSLSGTFGQFFVFNSLKLYGSLYTSLFTTLRKALSTIVSVYLFGHVLKPLQWCCVFVIFSTLIVQNYLKQLSKKVQNKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY56</accession>
    <name>A0A1J1GY56_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Mitochondrial ribosomal protein S15, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00507100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530299.1">
        <property type="nucleotide sequence ID" value="XM_028673892.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY56"/>
    <dbReference type="GeneID" id="39733604"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00507100"/>
    <dbReference type="OMA" id="CKDHPKK"/>
    <dbReference type="OrthoDB" id="441444at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00353">
        <property type="entry name" value="Ribosomal_S15p_S13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000589">
        <property type="entry name" value="Ribosomal_uS15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005290">
        <property type="entry name" value="Ribosomal_uS15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="uS15_NS1_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23321">
        <property type="entry name" value="RIBOSOMAL PROTEIN S15, BACTERIAL AND ORGANELLAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23321:SF26">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US15M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00312">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01387">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="S15/NS1 RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="300" mass="35267" checksum="AF4F89CD76A1BBF4" modified="2017-02-15" version="1">MSFLNKVFKINSFLHFKKKDIGFLKSSKRYESRVKAHRYTGITAVKTHAQKTEWYLKAERDFLAERNQIPNGYIGLWQYDDIKHLKDNIKSMLHLSCANNKQIHKFKKLNIRRLLQRRPFDTGSAAVQIGCLTEKILNLRAHLIQRCKDHPKKRTMSILLARRQKLMKYLYKTDFDLYKHTCNLLKIKCILFAIPDSRDRSRAINAAAVDGDRCKFLIRQKLWKGKYRPRPMKDSKGQTIRYTRHPVEQPPSDYALPKEYKPQISNSWPYGVKESYQKGVYTINNPTAPGLGYCPVPMLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY94</accession>
    <name>A0A1J1GY94_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zn-dependent PLC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00481100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530035.1">
        <property type="nucleotide sequence ID" value="XM_028673598.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733344"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00481100"/>
    <dbReference type="OMA" id="DENKMDP"/>
    <dbReference type="OrthoDB" id="285735at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004629">
        <property type="term" value="F:phospholipase C activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1440">
        <property type="entry name" value="PHAX RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019385">
        <property type="entry name" value="PHAX_RNA-binding_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038092">
        <property type="entry name" value="PHAX_RNA-binding_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001531">
        <property type="entry name" value="Zn_PLipaseC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10258">
        <property type="entry name" value="PHAX_RNA-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51346">
        <property type="entry name" value="PROKAR_ZN_DEPEND_PLPC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="885"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="918"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="961"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="994"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="domain" description="Zn-dependent PLC" evidence="6">
        <location>
            <begin position="1498"/>
            <end position="1654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="162"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="261"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="794"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1152"/>
            <end position="1176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1394"/>
            <end position="1426"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="522"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1092"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1298"/>
            <end position="1325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="17"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="162"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="183"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="199"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="217"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="261"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1152"/>
            <end position="1174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1414"/>
            <end position="1425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1654" mass="194797" checksum="CFD2C01095C9A683" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ45</accession>
    <name>A0A1J1GZ45_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00415800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529381.1">
        <property type="nucleotide sequence ID" value="XM_028672872.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732689"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00415800"/>
    <dbReference type="OMA" id="ITIMKSA"/>
    <dbReference type="OrthoDB" id="336882at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="456"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="591"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="705"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="865"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="922"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="953"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2028"/>
            <end position="2182"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2996"/>
            <end position="3035"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2028"/>
            <end position="2046"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2049"/>
            <end position="2059"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2060"/>
            <end position="2115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="2138"/>
            <end position="2149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2155"/>
            <end position="2177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3758" mass="451870" checksum="AD4BF5D43C79ABD6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZF2</accession>
    <name>A0A1J1GZF2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00041000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG97981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530779.1">
        <property type="nucleotide sequence ID" value="XM_028674426.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZF2"/>
    <dbReference type="GeneID" id="39728935"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00041000"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012949807" evidence="1">
        <location>
            <begin position="23"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="142" mass="17398" checksum="69E83BFD3EAAB850" modified="2017-02-15" version="1">MKTFTLCSKLFTFLLLIWIFHCFYNNDFSSCLIYKDKLQMKNRLKDERMLAEGGILEKKQTCIKECSEHYPYSEGEFYLIEYVYLMYMYIKCYNTFILSRFQEHDFFIEEKEMKYKCRDKILNAYRNNISAELPLEELLLTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZF3</accession>
    <name>A0A1J1GZF3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mitochondrial ribosomal protein S5, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00518200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530410.1">
        <property type="nucleotide sequence ID" value="XM_028674015.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZF3"/>
    <dbReference type="GeneID" id="39733715"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00518200"/>
    <dbReference type="OMA" id="HYCTSHW"/>
    <dbReference type="OrthoDB" id="309483at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000851">
        <property type="entry name" value="Ribosomal_uS5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_uS5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48277">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48277:SF1">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="S5 DRBM" evidence="3">
        <location>
            <begin position="606"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="85"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="849" mass="101842" checksum="DCABA195ED1B9E99" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZT3</accession>
    <name>A0A1J1GZT3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00039900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the proteasome complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase T1B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530761.1">
        <property type="nucleotide sequence ID" value="XM_028674404.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZT3"/>
    <dbReference type="GeneID" id="39728923"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00039900"/>
    <dbReference type="OMA" id="CSGCWCD"/>
    <dbReference type="OrthoDB" id="268479at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005839">
        <property type="term" value="C:proteasome core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03757">
        <property type="entry name" value="proteasome_beta_type_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF2">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA TYPE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 3 4" id="KW-0647">Proteasome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="241" mass="27392" checksum="1F42795BE7BF6FF2" modified="2017-02-15" version="1">MEIISINDNSNGNKSEKKENIIELNRSFRRWYPYIDNGGTVIGLTGKDYVILAADTRLSLSYSIYTRYCPKISKLTDRCIIGSSGMQSDIKTLHSLLQKKIQLFVLEHSHYPDIHVIARLLCVILYSRRFFPYYTFNLLAGVSDDNKGVLYNYDAIGSYCQSTHSCVGSGAALILPILDNRVEQKNQLIKNFNFNMRDDIDFVKDAITSATERDIYTGDKADIYIVDKLGINTTSLDLKQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H044</accession>
    <name>A0A1J1H044_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00448700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529709.1">
        <property type="nucleotide sequence ID" value="XM_028673236.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H044"/>
    <dbReference type="GeneID" id="39733020"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00448700"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="185" mass="20503" checksum="50F4A1C10FE129B9" modified="2017-02-15" version="1">MDPEQRESNNVSTDETANSDESSIPSLSSSPSDVSNISSNFEGYPSSIESQIHSGSDISQNFHQITTGNDSSENLQLPPELSIENLAFQALVLCFTMISGRISNRIILRRRRPHVDPVELGSDGEEEIEEVESQQEELDAHTNVEEEVLNGTNIDDIGDTSIYEEVYVLAEEDRGELRTDDCVIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H046</accession>
    <name>A0A1J1H046_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">AN1-like zinc finger family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00025300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530618.1">
        <property type="nucleotide sequence ID" value="XM_028674246.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H046"/>
    <dbReference type="GeneID" id="39728776"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00025300"/>
    <dbReference type="OMA" id="YKSHECP"/>
    <dbReference type="OrthoDB" id="431929at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1110.10">
        <property type="entry name" value="AN1-like Zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035896">
        <property type="entry name" value="AN1-like_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000058">
        <property type="entry name" value="Znf_AN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14677">
        <property type="entry name" value="ARSENITE INDUCUBLE RNA ASSOCIATED PROTEIN AIP-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14677:SF20">
        <property type="entry name" value="ZINC FINGER AN1-TYPE CONTAINING 2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01428">
        <property type="entry name" value="zf-AN1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00154">
        <property type="entry name" value="ZnF_AN1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118310">
        <property type="entry name" value="AN1-like Zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="AN1-type" evidence="4">
        <location>
            <begin position="11"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="AN1-type" evidence="4">
        <location>
            <begin position="92"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="145" mass="17464" checksum="56204460E1504C12" modified="2017-02-15" version="1">MAYFSDLSKQCEMIGCRNHDFLPFKCEYCNLNFCELHRNIQEHLCPKSKSFDSKVVLCEYCNLTLPDKTEEIKKHLIYKCSYKKKKMSILICNEKECKTVLNGINNYKCKNCKRNFCLPHRYPDVHNCIKESKEKSFFQKYFFFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H097</accession>
    <name>A0A1J1H097_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00041600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG97987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530784.1">
        <property type="nucleotide sequence ID" value="XM_028674431.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H097"/>
    <dbReference type="GeneID" id="39728941"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00041600"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022139">
        <property type="entry name" value="Fam-L/Fam-M-like_plasmodium"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12420">
        <property type="entry name" value="DUF3671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="101" mass="11998" checksum="E38710DBC3864159" modified="2017-02-15" version="1">MKIFTLCLKIFTFFILTWIFHCFYNYDSSRSLINKDTMQIKNKLKNERLLAEVGVLEKKQTVELELVSNSNETNEISNKSKDKILNDYWNNNSIEDVLQQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0A3</accession>
    <name>A0A1J1H0A3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00453400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529757.1">
        <property type="nucleotide sequence ID" value="XM_028673289.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0A3"/>
    <dbReference type="GeneID" id="39733067"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00453400"/>
    <dbReference type="OMA" id="HFRGYYY"/>
    <dbReference type="OrthoDB" id="368657at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="67" mass="8464" checksum="9344C54C4ADFDEA9" modified="2017-02-15" version="1">MLLQLNLSFFLKNPFNSQNTIIPMFFTPFHLLRPRKKTQRVDRCRTKKQYKNRRHFRGFYYRWMGSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0T2</accession>
    <name>A0A1J1H0T2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Gamma-tubulin complex component, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00446600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TUBGCP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529688.1">
        <property type="nucleotide sequence ID" value="XM_028673213.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0T2"/>
    <dbReference type="GeneID" id="39732999"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00446600"/>
    <dbReference type="OMA" id="HFAKYLF"/>
    <dbReference type="OrthoDB" id="5860513at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000930">
        <property type="term" value="C:gamma-tubulin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043015">
        <property type="term" value="F:gamma-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051011">
        <property type="term" value="F:microtubule minus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007020">
        <property type="term" value="P:microtubule nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051225">
        <property type="term" value="P:spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1900">
        <property type="entry name" value="Gamma-tubulin complex, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007259">
        <property type="entry name" value="GCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040457">
        <property type="entry name" value="GCP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042241">
        <property type="entry name" value="GCP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041470">
        <property type="entry name" value="GCP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302">
        <property type="entry name" value="GAMMA TUBULIN COMPLEX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19302:SF14">
        <property type="entry name" value="GAMMA-TUBULIN COMPLEX COMPONENT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04130">
        <property type="entry name" value="GCP_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17681">
        <property type="entry name" value="GCP_N_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gamma tubulin complex component protein N-terminal" evidence="7">
        <location>
            <begin position="381"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="domain" description="Gamma tubulin complex component C-terminal" evidence="6">
        <location>
            <begin position="802"/>
            <end position="1200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1225" mass="145118" checksum="30E1A361694BC324" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H113</accession>
    <name>A0A1J1H113_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00454500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529768.1">
        <property type="nucleotide sequence ID" value="XM_028673301.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H113"/>
    <dbReference type="GeneID" id="39733078"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00454500"/>
    <dbReference type="OMA" id="RTARWLN"/>
    <dbReference type="OrthoDB" id="370515at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="131" mass="16274" checksum="D8D3E94C63B6072F" modified="2017-02-15" version="1">MIKFFRRKFFKINKFMNFKALKTSKIFNIKKEIIINSLEEKNEKQINDALKYFSKSEIFYLFFIPFAFVSIYIFVMWNIFKYICDIKDINHFLKILRWLKGKESYPYEYLQNKKKKKRKSESIIVIEKKFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H155</accession>
    <name>A0A1J1H155_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein S12, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00062800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530986.1">
        <property type="nucleotide sequence ID" value="XM_028674656.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H155"/>
    <dbReference type="GeneID" id="39729153"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00062800"/>
    <dbReference type="OMA" id="MNDKICE"/>
    <dbReference type="OrthoDB" id="414309at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03368">
        <property type="entry name" value="Ribosomal_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000192">
        <property type="entry name" value="Mitochondrial ribosomal protein S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006032">
        <property type="entry name" value="Ribosomal_uS12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005679">
        <property type="entry name" value="Ribosomal_uS12_bac"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00981">
        <property type="entry name" value="rpsL_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11652">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S12 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00164">
        <property type="entry name" value="Ribosom_S12_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01034">
        <property type="entry name" value="RIBOSOMALS12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00043092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG98189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="311" mass="37266" checksum="3D7BF85B4FE54298" modified="2017-02-15" version="1">MFFSILNKINNKNIFPDVKISLILKKNQSFYFVKNISYFFNEKIIYNKKVDNTQILSKRVINYTVGLNNVKSAYYQNNGKKYIHTDSIKNKENFNRRKYFYNIIENKYFSTKNIRGRLFYKRRPKQIPKLKKKNWRSKWLEGAPQKRGICLKVRVQTPKKPNSGLKKIARVRLSTGRIVSVYIPGIGHNLNTHSIILVRGGRCKDIPGCNYKAIRGVYDLLPVKNRFRGRSKYGVKLSEDKRKHLVERYNFKHITIKKDIEEFNKYKWFNYVDKDKNLREKPLSPNENVPINIFHFNTYYRNKKFQQNNEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H253</accession>
    <name>A0A1J1H253_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00498100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000103">
        <property type="protein sequence ID" value="CRG97406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530208.1">
        <property type="nucleotide sequence ID" value="XM_028673791.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H253"/>
    <dbReference type="GeneID" id="39733514"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00498100"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006496">
        <property type="entry name" value="CHP01606_Plasmodium_spp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09688">
        <property type="entry name" value="Wx5_PLAF3D7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012859637" evidence="2">
        <location>
            <begin position="23"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="204" mass="24605" checksum="2770A7541624ADEC" modified="2017-02-15" version="1">MKSLILYLKITTFLLLIWMYQCFYNCDCNKSFIDKNILQTKNKLKYERVLTEGDIAGKMQTYSEGYLEECSLDNKKNKRENPVQNENPRDRWQRKTNPLFRKIFDKKTSEMDPKWRDQKWNNEWNKISANKVNELSEIFHRSDISEEEKKKLIRSVKDELDTEFAKFLVECKNEMKDNKGESKSKKEMIDNKTESKSKKEMIRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3A0</accession>
    <name>A0A1J1H3A0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Early transcribed membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ETRAMP</name>
        <name evidence="4" type="ORF">PGAL8A_00377100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000119">
        <property type="protein sequence ID" value="CRG97965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530764.1">
        <property type="nucleotide sequence ID" value="XM_028674407.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3A0"/>
    <dbReference type="GeneID" id="39732301"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00377100"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006389">
        <property type="entry name" value="Early_transc_mb_plasmodium"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01495">
        <property type="entry name" value="ETRAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09716">
        <property type="entry name" value="ETRAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012656054" evidence="3">
        <location>
            <begin position="25"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="115" mass="12768" checksum="647A5043739B22A1" modified="2017-02-15" version="1">MKFSKIFFFFAFFLTIKLLAPCSCDVDRVENPRENDVGLMKLEEDLERKKKNEKMILISSVATGIAVLLGSALGLGYYAQKNKSTGKPKSEKQGEEKSESSEESSESSEESGDKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3J5</accession>
    <name>A0A1J1H3J5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Ribonucleases P/MRP protein subunit POP1, putative</fullName>
            <ecNumber evidence="8">3.1.26.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">POP1</name>
        <name evidence="8" type="ORF">PGAL8A_00049800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.5" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530860.1">
        <property type="nucleotide sequence ID" value="XM_028674515.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3J5"/>
    <dbReference type="GeneID" id="39729023"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00049800"/>
    <dbReference type="OMA" id="SRRIFRY"/>
    <dbReference type="OrthoDB" id="442863at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005655">
        <property type="term" value="C:nucleolar ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000172">
        <property type="term" value="C:ribonuclease MRP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039182">
        <property type="entry name" value="Pop1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055079">
        <property type="entry name" value="POP1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009723">
        <property type="entry name" value="Pop1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012590">
        <property type="entry name" value="POPLD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22731">
        <property type="entry name" value="RIBONUCLEASES P/MRP PROTEIN SUBUNIT POP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22731:SF3">
        <property type="entry name" value="RIBONUCLEASES P_MRP PROTEIN SUBUNIT POP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22770">
        <property type="entry name" value="POP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06978">
        <property type="entry name" value="POP1_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08170">
        <property type="entry name" value="POPLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Pop1 N-terminal" evidence="5">
        <location>
            <begin position="131"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="Pop1 N-terminal" evidence="5">
        <location>
            <begin position="199"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="POPLD" evidence="6">
        <location>
            <begin position="824"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="domain" description="POP1 C-terminal" evidence="7">
        <location>
            <begin position="981"/>
            <end position="1174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="315"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="7"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="337"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF22770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG98063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1182" mass="141231" checksum="AB0DFE6540AD7E99" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKW4</accession>
    <name>A0A1J1GKW4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">WD-repeat protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00066000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG92956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525778.1">
        <property type="nucleotide sequence ID" value="XM_028671087.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKW4"/>
    <dbReference type="GeneID" id="39729185"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00066000"/>
    <dbReference type="OMA" id="CLFHNNF"/>
    <dbReference type="OrthoDB" id="972532at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051350">
        <property type="entry name" value="WD_repeat-ST_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22838">
        <property type="entry name" value="WD REPEAT PROTEIN 26-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22838:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23627">
        <property type="entry name" value="LisH_WDR26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="703"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="746"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="139"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="446"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="144"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="446"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG92956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1035" mass="121810" checksum="A45E3E4BA0643D86" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKX6</accession>
    <name>A0A1J1GKX6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA methyltransferase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00072900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525847.1">
        <property type="nucleotide sequence ID" value="XM_028674901.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKX6"/>
    <dbReference type="GeneID" id="39729254"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00072900"/>
    <dbReference type="OMA" id="LEWICCT"/>
    <dbReference type="OrthoDB" id="270651at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18095">
        <property type="entry name" value="SpoU-like_rRNA-MTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051259">
        <property type="entry name" value="rRNA_Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43191">
        <property type="entry name" value="RRNA METHYLTRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43191:SF2">
        <property type="entry name" value="RRNA METHYLTRANSFERASE 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="tRNA/rRNA methyltransferase SpoU type" evidence="3">
        <location>
            <begin position="204"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="350" mass="40925" checksum="9BDB3EFE97D6251E" modified="2017-02-15" version="1">MFLFANISKKYVTNRNFISEFFLMFERNVSLIHKNLIKTNGKNFLSVIHNNQNEIIHDENLKPFWLNLNGKEKNKLNHYAKQGDKEKEDSEFLNISKRSKMMKYIIRLRKKKNFRKKMNEFFVKNSKTILYMSNNKNLLFEAVLSSNKDLLQHFRGKCKKLYYVNYDILNYIFYDSVNVMKEKNDSVAILKIPNVVNKIKNIKFLLAFDRIRYAYNLGKILNVAYSMNIDYLFYLHNTVDPFNSKVIEITNGSHLNIPYMYGSYKDLKDLCSENNLVPIVAHINGLNPHNILKESNKNGICLILGNESTGPHPDTLKFAKPISLPMHEMTNSLNVSVAASILIHYIKNML</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLC0</accession>
    <name>A0A1J1GLC0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Zinc finger protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00070100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG92997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525819.1">
        <property type="nucleotide sequence ID" value="XM_028673643.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729226"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00070100"/>
    <dbReference type="OMA" id="AMCRNFM"/>
    <dbReference type="OrthoDB" id="430732at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="227"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="265"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="301"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="227"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="265"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="301"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="435"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="716"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1167"/>
            <end position="1193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="736"/>
            <end position="1065"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG92997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1507" mass="176953" checksum="20A43608978BEEAD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLE1</accession>
    <name>A0A1J1GLE1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Vacuolar protein sorting-associated protein 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">VPS2</name>
        <name evidence="2" type="ORF">PGAL8A_00086000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525978.1">
        <property type="nucleotide sequence ID" value="XM_028671111.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLE1"/>
    <dbReference type="GeneID" id="39729384"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00086000"/>
    <dbReference type="OMA" id="EIMRMEM"/>
    <dbReference type="OrthoDB" id="2329734at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005024">
        <property type="entry name" value="Snf7_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10476">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03357">
        <property type="entry name" value="Snf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="6"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="209" mass="24590" checksum="27A96EBF7ED9FD1E" modified="2017-02-15" version="1">MGIFSSKNLEECLREEKRNLNRSIRELEREIYKLENEKKQIEKNIKLYAKKNDITLVRTLAKDLVKIRQTVSKYSKIKSHLFSMKIKLQSVKSSEQLSKSLKDINKLIKRVNNYLKLKDINSSINEFQKQNNEVSLKEDMLDDLFDTLNYDIDMIEEEDEIVAKVLDELGIQLNSKLEEIPAVNTIQNEKNEDVNISNLEERINNLKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLN8</accession>
    <name>A0A1J1GLN8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00083700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525955.1">
        <property type="nucleotide sequence ID" value="XM_028670854.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLN8"/>
    <dbReference type="GeneID" id="39729361"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00083700"/>
    <dbReference type="OrthoDB" id="368723at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="133" mass="15947" checksum="F62655297609A3B6" modified="2017-02-15" version="1">MSYAACPLNFININQNQKEDLLRFEASAIDNFKHLKIIEFKSRIRISLIIFVISLFIFLTYKFRNNKIIIETSNNIPLIIFVSFFFFFLLKYYYKNLFKSKNYIKSLNKTLKSFNLYLDKKSLKLCIIGLKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLP6</accession>
    <name>A0A1J1GLP6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Double-strand break repair protein MRE11, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">MRE11</name>
        <name evidence="3" type="ORF">PGAL8A_00104000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526156.1">
        <property type="nucleotide sequence ID" value="XM_028673088.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLP6"/>
    <dbReference type="GeneID" id="39729565"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00104000"/>
    <dbReference type="OMA" id="AIYAIGW"/>
    <dbReference type="OrthoDB" id="30417at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030870">
        <property type="term" value="C:Mre11 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000014">
        <property type="term" value="F:single-stranded DNA endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042138">
        <property type="term" value="P:meiotic DNA double-strand break formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097552">
        <property type="term" value="P:mitochondrial double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007095">
        <property type="term" value="P:mitotic G2 DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.110">
        <property type="entry name" value="Mre11, capping domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038487">
        <property type="entry name" value="Mre11_capping_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007281">
        <property type="entry name" value="Mre11_DNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10139">
        <property type="entry name" value="DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10139:SF1">
        <property type="entry name" value="DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04152">
        <property type="entry name" value="Mre11_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01347">
        <property type="entry name" value="Mre11_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mre11 DNA-binding" evidence="2">
        <location>
            <begin position="811"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="526"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="248"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="529"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="562"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1141" mass="136242" checksum="28A85A8D63043C82" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLS4</accession>
    <name>A0A1J1GLS4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2</fullName>
            <shortName evidence="8">Oligosaccharyl transferase subunit OST2</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00098100</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the oligosaccharyltransferase (OST) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Endoplasmic reticulum membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the DAD/OST2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526097.1">
        <property type="nucleotide sequence ID" value="XM_028672433.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLS4"/>
    <dbReference type="GeneID" id="39729505"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00098100"/>
    <dbReference type="OrthoDB" id="445566at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003038">
        <property type="entry name" value="DAD/Ost2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10705">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10705:SF0">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02109">
        <property type="entry name" value="DAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="89"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="107" mass="12750" checksum="E84AEA4FB71D48DC" modified="2017-02-15" version="1">MKKILEKFYNNYSSTSRRIKFIDIYIILTFFHLIILSVYAYFSYSFHEKISVTAIFTAIGNITFLVAMREQFTHKSIFNLKREKIIFDFILCSLVLHIGAFSYMHLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM86</accession>
    <name>A0A1J1GM86_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Protein transport protein SEC61 subunit beta, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00114900</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SEC61-beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526265.1">
        <property type="nucleotide sequence ID" value="XM_028674298.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM86"/>
    <dbReference type="GeneID" id="39729674"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00114900"/>
    <dbReference type="OMA" id="RTNHLHR"/>
    <dbReference type="OrthoDB" id="5401193at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005784">
        <property type="term" value="C:Sec61 translocon complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030671">
        <property type="entry name" value="Sec61-beta/Sbh"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016482">
        <property type="entry name" value="SecG/Sec61-beta/Sbh"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13509">
        <property type="entry name" value="SEC61 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03911">
        <property type="entry name" value="Sec61_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006398">
        <property type="entry name" value="Sec61_beta_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="20"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG93443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="78" mass="8507" checksum="887589931F0F6A4E" modified="2017-02-15" version="1">MSGTPIIVGGMRTTARRRQNTGSSNTSKQRRNLSGNTNSIVKFYGDDSPGFKLTPQTVLIATLIFMATVVILHIINKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM92</accession>
    <name>A0A1J1GM92_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00122000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526335.1">
        <property type="nucleotide sequence ID" value="XM_028674733.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM92"/>
    <dbReference type="GeneID" id="39729745"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00122000"/>
    <dbReference type="OMA" id="YQRVKEM"/>
    <dbReference type="OrthoDB" id="10259720at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003341">
        <property type="term" value="P:cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060285">
        <property type="term" value="P:cilium-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036159">
        <property type="term" value="P:inner dynein arm assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033290">
        <property type="entry name" value="CCDC39"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18962">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18962:SF0">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24161">
        <property type="entry name" value="CCDC39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="287"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="476"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="677"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="925"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1086" mass="130160" checksum="C02B6E66B57324A3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMD3</accession>
    <name>A0A1J1GMD3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Trafficking protein particle complex subunit 11 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00122300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526338.1">
        <property type="nucleotide sequence ID" value="XM_028674737.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729748"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00122300"/>
    <dbReference type="OMA" id="QYKEMEL"/>
    <dbReference type="OrthoDB" id="371916at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="506"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="584"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1082"/>
            <end position="1128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1089"/>
            <end position="1119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1624" mass="195130" checksum="10323F1BF53CABBE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMH5</accession>
    <name>A0A1J1GMH5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fam-a protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00135300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526470.1">
        <property type="nucleotide sequence ID" value="XM_028674883.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMH5"/>
    <dbReference type="SMR" id="A0A1J1GMH5"/>
    <dbReference type="GeneID" id="39729878"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00135300"/>
    <dbReference type="OMA" id="GFWPELM"/>
    <dbReference type="OrthoDB" id="10251371at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22854">
        <property type="entry name" value="PfVFT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049856">
        <property type="entry name" value="PfVFT1-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013085608" description="Fam-a protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="300" mass="33887" checksum="273C641BD9870FE9" modified="2017-02-15" version="1">MKVFFKIVFLIFLTYIFQGFCNETNIKLHKSSRLMELYHAAVKVLISNGQIDALIKKHNVDYSPTESLDGISDIEQVDISSDINDVLSKILKNKEVKVGALKGKNWGSIGDYNEDPPTGFWPELMFLIWKTISKRIFDDENAIKVKYLFFVDVFNALNKNEIDITENYFLSLPSSTEEGLRNDTSKISQGLSLITHSNKIIVLKELNINNLNDLKSYISKNSNVKIACLTEANCKAVKDVFESGVKYVHKGFSSYSDLSESVLSKENLAGIVSGLPTDFNDPKLTIFDTLIKTSHSPFFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMI5</accession>
    <name>A0A1J1GMI5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Inner membrane complex protein 1i, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">IMC1i</name>
        <name evidence="1" type="ORF">PGAL8A_00116700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526283.1">
        <property type="nucleotide sequence ID" value="XM_028674499.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMI5"/>
    <dbReference type="GeneID" id="39729692"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00116700"/>
    <dbReference type="OMA" id="KNETMYN"/>
    <dbReference type="OrthoDB" id="365974at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022086">
        <property type="entry name" value="IMCp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12314">
        <property type="entry name" value="IMCp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="493" mass="57180" checksum="A6A29808EAD6588B" modified="2017-02-15" version="1">MEGETGNFPSNIPYSFEHSKNISKQILKPIRQEKIVKVPVTQYIEKIIEKEQVKYVNKYVDVIKPIITYKTKHIPKPIYLDKIKYEPKLIEKEKIIHIPKIEYRNKVVEIPVYVHKEKIIEKKVPLVIERVVPVLKIKKIEKEVLTNTVEIPEISEITKNEMNIKISKNSYESNKEILSKVPIKKNTYALDLKNSKEDVYIPETSRRYESLNDPIMYSSMQVHHSEIDQLKAQKLNNGNSNTTSEEGSYKDRLYNKNETGYHDATNDDVNSNLISDNENRINNTEINSKEYVKNMEENYYNIEELHKNFNTTHVSIHLPTTQNVVQESIEQSYMNSYDNNCNISMNHIIDNNCINDNGNTPNRYNEDSMKAITNEKLIHESCNGSKRYSSIPIQENSHGNYRAITGDHIEMEQKSVNPSNMHFSYENYALSQNIYGQRSIPSKSNFKPSYANSNGQAFVSVRPATIVELKPKPRKNKTSICNFINNCCGRNDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMR4</accession>
    <name>A0A1J1GMR4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">methylated diphthine methylhydrolase</fullName>
            <ecNumber evidence="6">3.1.1.97</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00136500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>diphthine methyl ester-[translation elongation factor 2] + H2O = diphthine-[translation elongation factor 2] + methanol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:42656"/>
            <dbReference type="Rhea" id="RHEA-COMP:10172"/>
            <dbReference type="Rhea" id="RHEA-COMP:10173"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17790"/>
            <dbReference type="ChEBI" id="CHEBI:79005"/>
            <dbReference type="ChEBI" id="CHEBI:82696"/>
            <dbReference type="EC" id="3.1.1.97"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DPH7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.97" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526482.1">
        <property type="nucleotide sequence ID" value="XM_028674897.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMR4"/>
    <dbReference type="GeneID" id="39729890"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00136500"/>
    <dbReference type="OMA" id="YCCDDIC"/>
    <dbReference type="OrthoDB" id="273771at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061685">
        <property type="term" value="F:diphthine methylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052415">
        <property type="entry name" value="Diphthine_MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46042">
        <property type="entry name" value="DIPHTHINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46042:SF1">
        <property type="entry name" value="DIPHTHINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="170"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="213"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00039131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="341" mass="39428" checksum="723BF805339C7E94" modified="2017-02-15" version="1">MIKYNLKYCCDDICIFPSCALLNYDDKFSDTFGLTAVSTYQLKNNNKNNKQKKKGKIYLFRLTENISENDNSDIDYFLSYEKNINFHSGVLQSNYIFSNENLLLGSVCVNGFYLSDVNKGNYEKLIQTKDEENNSGLSFEAFDNKTEAICVTFSNGDICYLVDGIKKKLWKGHEYHIWSCTFNGSKDIITTGSDDCSFIIWDLRTDNFVQKNKKSHSQGVTSVNFEIVNNLLYTGSYDNKIRIFDLRNICDPLQIIDVNSSIWRLKFLYKNKKLNKLLVAACDGGAKVFKKINDEFIFKKGVTNNNELTYGIDAIDIPNKKKKKKIYFTCSFYNKEVQMWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMT4</accession>
    <name>A0A1J1GMT4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00144800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526564.1">
        <property type="nucleotide sequence ID" value="XM_028674987.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMT4"/>
    <dbReference type="GeneID" id="39729972"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00144800"/>
    <dbReference type="OMA" id="NDPKCLV"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="33"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="145" mass="17320" checksum="0737867B944B260A" modified="2017-02-15" version="1">MSYGWLTESTVFKKKEEIIELSKDKLFNESKNNKKSENSIDKLNNIVNSYLQNIKEKKKNPIGKKKLSYFENLYNSKNDGVEKRNEQDKTNLSLKKKINKKEKYEQLKKKGSNNYNCLVNFELKKDLEHELEEIRKLKEKKIKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNQ5</accession>
    <name>A0A1J1GNQ5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00381500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526932.1">
        <property type="nucleotide sequence ID" value="XM_028670151.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNQ5"/>
    <dbReference type="GeneID" id="39732345"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00381500"/>
    <dbReference type="OrthoDB" id="369686at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="288" mass="34918" checksum="FFC5D8E75B3A3556" modified="2017-02-15" version="1">MLTCRTLSSNFKEGLNLLVNILLCKLIFNIYYTFQKIKDNNNIKNYKNEKKKNWNLKNLEKSKKNIEKFIDLFLIILNILEGNNKFFIQHVLENYATINLNNGQKKKKNVTKFHDIFLMYYIYNNSLLQRKKNEDNNIKESYKKVNLEKNILIGDKEIYSYMNKIPIIDNYIDKYKTYSRNSLINEFNNFLNVFYLKKLPIHENDNEIKKKNENLIDEDFVTKNLFSEYFNSCRKNNKLNILIKEVNLNNLSYFHNILFKNIKFIRSFNRESNEEEIENYKLSKLFEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNX7</accession>
    <name>A0A1J1GNX7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Succinate dehydrogenase subunit 4, putative</fullName>
            <ecNumber evidence="2">1.2.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">SDH4</name>
        <name evidence="2" type="ORF">PGAL8A_00386600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.-" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526983.1">
        <property type="nucleotide sequence ID" value="XM_028670208.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNX7"/>
    <dbReference type="GeneID" id="39732396"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00386600"/>
    <dbReference type="OrthoDB" id="370269at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="107" mass="12835" checksum="5A9C1F0E043229D3" modified="2017-02-15" version="1">MDNSSVNYCNMLLNKIFGSSIEKYFKIVNVSIIIILMTVLHYIYSFDEKSTYYNDNILLRMYYGFLFCLIGFAISINWIYYEYIKNKKSKKNKNDQQLETKDSKKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP15</accession>
    <name>A0A1J1GP15_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00174500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526859.1">
        <property type="nucleotide sequence ID" value="XM_028670070.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP15"/>
    <dbReference type="GeneID" id="39730272"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00174500"/>
    <dbReference type="OMA" id="KNESDCY"/>
    <dbReference type="OrthoDB" id="365216at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013176129" evidence="1">
        <location>
            <begin position="23"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="125" mass="14690" checksum="B62A8A3DAB72260D" modified="2017-02-15" version="1">MLQKVFFSSLCLFLLQLKYVLCYNIKCSSLTNNEEILSYCKNNSECYVKNVNDSEYSSIECKCRKQINDFFFAGPDCSIKIPYHYKTTKNNGVYNTTWLEDLFNLNIWKNEENRVGRICVNPQCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP54</accession>
    <name>A0A1J1GP54_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Histone H2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00395400</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the histone H2A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527071.1">
        <property type="nucleotide sequence ID" value="XM_028670305.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP54"/>
    <dbReference type="GeneID" id="39732484"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00395400"/>
    <dbReference type="OMA" id="MNKKGAP"/>
    <dbReference type="OrthoDB" id="9421954at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00074">
        <property type="entry name" value="HFD_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000005">
        <property type="entry name" value="Histone H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002119">
        <property type="entry name" value="Histone_H2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032454">
        <property type="entry name" value="Histone_H2A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032458">
        <property type="entry name" value="Histone_H2A_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23430">
        <property type="entry name" value="HISTONE H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16211">
        <property type="entry name" value="Histone_H2A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00620">
        <property type="entry name" value="HISTONEH2A"/>
    </dbReference>
    <dbReference type="SMART" id="SM00414">
        <property type="entry name" value="H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00046">
        <property type="entry name" value="HISTONE_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 8" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="9">
        <location>
            <begin position="33"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="Histone H2A C-terminal" evidence="10">
        <location>
            <begin position="117"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG94250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="157" mass="16335" checksum="1DB770B2DA60D0D3" modified="2017-02-15" version="1">MEVAGKVCGKVGGKVGGKVLGLGKGGKGKTGSGKTKKAPLSRASRAGLQFPVGRVHRMLKCRISSDGRVGSTAAVYAAAILEYLTAEVLELAGNATKDLKVKRITPRHLQLAIRGDEELDTLIKATIAGGGVIPHIHKALMNKVPVPPTATKKPKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP85</accession>
    <name>A0A1J1GP85_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">methionine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00381200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.10" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526929.1">
        <property type="nucleotide sequence ID" value="XM_028670148.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP85"/>
    <dbReference type="GeneID" id="39732342"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00381200"/>
    <dbReference type="OMA" id="NMFLPDR"/>
    <dbReference type="OrthoDB" id="24670at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004825">
        <property type="term" value="F:methionine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006431">
        <property type="term" value="P:methionyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.220.10:FF:000003">
        <property type="entry name" value="Methionine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023457">
        <property type="entry name" value="Met-tRNA_synth_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033911">
        <property type="entry name" value="MetRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43326:SF1">
        <property type="entry name" value="METHIONINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43326">
        <property type="entry name" value="METHIONYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01041">
        <property type="entry name" value="TRNASYNTHMET"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 7 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methionyl/Leucyl tRNA synthetase" evidence="9">
        <location>
            <begin position="179"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Leucyl tRNA synthetase" evidence="9">
        <location>
            <begin position="326"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Leucyl tRNA synthetase" evidence="9">
        <location>
            <begin position="481"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="92"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG94108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="748" mass="89715" checksum="D2B200C587B32631" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPC7</accession>
    <name>A0A1J1GPC7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00405500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527172.1">
        <property type="nucleotide sequence ID" value="XM_028670417.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPC7"/>
    <dbReference type="GeneID" id="39732585"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00405500"/>
    <dbReference type="OMA" id="HEEKTFY"/>
    <dbReference type="OrthoDB" id="377342at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="370"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="395"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="434"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="548"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="599"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="799"/>
            <end position="820"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1050" mass="123429" checksum="9331F74F73B18B56" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPG7</accession>
    <name>A0A1J1GPG7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">GAF domain-related protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00402100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527138.1">
        <property type="nucleotide sequence ID" value="XM_028670380.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732551"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00402100"/>
    <dbReference type="OMA" id="QYCTLIG"/>
    <dbReference type="OrthoDB" id="430821at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019537">
        <property type="entry name" value="TMEM65"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21706">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21706:SF15">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10507">
        <property type="entry name" value="TMEM65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="277"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="314"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="361"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="GAF" evidence="7">
        <location>
            <begin position="401"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="583"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="627"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="875"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="642"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="682"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="875"/>
            <end position="889"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1323" mass="158648" checksum="94E0E04A11605E40" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQG2</accession>
    <name>A0A1J1GQG2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00190300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000027">
        <property type="protein sequence ID" value="CRG94506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527323.1">
        <property type="nucleotide sequence ID" value="XM_028670585.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQG2"/>
    <dbReference type="GeneID" id="39730428"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00190300"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="139" mass="16793" checksum="3AD7DA982B16EEB2" modified="2017-02-15" version="1">MKTFTLCLKIFIFLLLIWIFHCFYNYDFNRSLNYKDTLQIKNRLKDERMLAESGILKKKQTCIKERLEHYPSSEKNNKYDVLVYFKNIYNIWYNAIILSICELLSKKNDEMIKKCQVKEVDALRKNTSLFLCPQLSMTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQI0</accession>
    <name>A0A1J1GQI0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">V-type H(+)-translocating pyrophosphatase, putative</fullName>
            <ecNumber evidence="2">3.6.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">VP1</name>
        <name evidence="2" type="ORF">PGAL8A_00216400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.1" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527582.1">
        <property type="nucleotide sequence ID" value="XM_028670873.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQI0"/>
    <dbReference type="GeneID" id="39730691"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00216400"/>
    <dbReference type="OrthoDB" id="370791at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="273"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="838" mass="99438" checksum="4C15F7ED3F294205" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQI8</accession>
    <name>A0A1J1GQI8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00217200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527590.1">
        <property type="nucleotide sequence ID" value="XM_028670882.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730699"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00217200"/>
    <dbReference type="OMA" id="KYDRHKL"/>
    <dbReference type="OrthoDB" id="392768at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052098">
        <property type="entry name" value="Presynaptic_Scaffold_Bsn/Pclo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14113:SF13">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14113">
        <property type="entry name" value="PICCOLO/BASSOON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="528"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="564"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1317"/>
            <end position="1335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="2203"/>
            <end position="2225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="2544"/>
            <end position="2562"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="2577"/>
            <end position="2596"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="2903"/>
            <end position="2922"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2924" mass="357219" checksum="42417A23ECC52412" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQJ7</accession>
    <name>A0A1J1GQJ7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Exonuclease V, mitochondrial, putative</fullName>
            <ecNumber evidence="3">3.1.11.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00218000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EXO5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.5" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527598.1">
        <property type="nucleotide sequence ID" value="XM_028670891.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQJ7"/>
    <dbReference type="GeneID" id="39730707"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00218000"/>
    <dbReference type="OMA" id="CPDKPLG"/>
    <dbReference type="OrthoDB" id="354769at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008854">
        <property type="term" value="F:exodeoxyribonuclease V activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045145">
        <property type="term" value="F:single-stranded DNA 5'-3' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.320.10:FF:000009">
        <property type="entry name" value="Exonuclease V, mitochondrial, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019190">
        <property type="entry name" value="EXOV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14464">
        <property type="entry name" value="EXONUCLEASE V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14464:SF4">
        <property type="entry name" value="EXONUCLEASE V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09810">
        <property type="entry name" value="Exo5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="11"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="353" mass="42267" checksum="2C3CE1D9888C0F5A" modified="2017-02-15" version="1">MLKTYNVIWKKEEEEEDLKNEKKRKIFNEREIVDEKKDITNSDFDELINDIEDLLEEQQINETEKLYKESKPPNEKFNKKNKLSITDLSAQLWCEQQLELVLTTGRKRETEAMRLGIERHEVLEKADHEIVDVEVNTREESLGYRLLNTITLLGQLFECKKAREVWVFGIIRNYVLRGIIDELRIEYDNISKREFLIISDTKTRKEKKEPSLAQKRTSAIQVQTYCLILQQLRNGKADFKKLFEIYECDPQFEFTAVDLKKYKNLENLSKEVNKLFIKLPKIKEEMEIVYEHQGKEFARNLIPYFYHSTIYTINFLLDYWEGKRPSEVVENSDKWKCKFCDFVKNCVRCPLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQK7</accession>
    <name>A0A1J1GQK7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00219600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527614.1">
        <property type="nucleotide sequence ID" value="XM_028670908.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQK7"/>
    <dbReference type="GeneID" id="39730723"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00219600"/>
    <dbReference type="OMA" id="KRVHVWI"/>
    <dbReference type="OrthoDB" id="432990at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="128"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="299" mass="36165" checksum="74D089CB41A1BEDD" modified="2017-02-15" version="1">MSSIKINKDEGKRVHIWIKSAIGTPNRRQFKHKNIMYPYFRMYKSPYRARDSRTRQAFWPCVDKYPWHTHQKRWVKMEQLNIKFFSEFTNRPPNKKNLFEVCHTLPFNGINCLFWNPIYINSHKFFLKNCKKNDENEEEKECKEHNEDIEDKNDNELNMNSKENEVCNIENKNTVNNYDENKKIIRICNFYYIVDKEVKNNVYFYLKYIKYTMRPFRGKIIGDLYLNERKIRDNISAKGIVNGEWKFSFPHIKVNQKVANITLNDNLINEELEKNIIKNLVIVDKYTYRPPLPKCFSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQP2</accession>
    <name>A0A1J1GQP2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Alpha/beta hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00217600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527594.1">
        <property type="nucleotide sequence ID" value="XM_028670886.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730703"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00217600"/>
    <dbReference type="OMA" id="TLYISYY"/>
    <dbReference type="OrthoDB" id="10249433at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277">
        <property type="entry name" value="ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277:SF81">
        <property type="entry name" value="PROTEIN ABHD13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="644"/>
            <end position="671"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1483" mass="178675" checksum="E50395D79DD4CF3B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRH1</accession>
    <name>A0A1J1GRH1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Chromatin assembly factor 1 subunit, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00241600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527831.1">
        <property type="nucleotide sequence ID" value="XM_028671150.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRH1"/>
    <dbReference type="GeneID" id="39730944"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00241600"/>
    <dbReference type="OMA" id="PHEEGCL"/>
    <dbReference type="OrthoDB" id="427795at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022052">
        <property type="entry name" value="Histone-bd_RBBP4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050459">
        <property type="entry name" value="WD_repeat_RBAP46/RBAP48/MSI1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22850">
        <property type="entry name" value="WD40 REPEAT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12265">
        <property type="entry name" value="CAF1C_H4-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Histone-binding protein RBBP4-like N-terminal" evidence="5">
        <location>
            <begin position="38"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="354"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="464"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="505" mass="58146" checksum="64E01BC383310860" modified="2017-02-15" version="1">MDIKNEKNKSYDLKDSYESKTPIEKETNENTNVDILNERYIIWRKNTPFLYSSLLKNKLDWPSLTVEFLGSDNSFKSKTNYFTNKILLGTHTSNQDFEYVYIGEIKFPLYSVKEDVLQYENYSGFISSKKKKKAYPLPSFEIKAKLLHPGEVIRATHLPSNPFFIVTQTNNGNILLFDYTKHPSFPSDVSTCYPQMILKGHKSEGSGLCWNINKVYDNYRNPNTYNEENESNINENNSGFGEVNPSDLLLASCSVDGSICLWDINKGTKCNDVPRTYGLNKSGKITDFNIKTYENTPTIDPLCTWINKNKEISLNDIFFHPKFNNALGVCDDDGYMSLYDIRKKNFFSKPEINFKDHNEAMNTFSFDNFSEYIFSCGYSDGLISIWDMRYNKESLLKINYHTQSINRIKFCMMSSGIFGSCSDDGTTCIWDISRNSASYEQIKKSEDDIYNSSKKIPKQLLFVHGGHIGSVYDMAWANSNTFLVATVGVDNSLQVWHMNEQFIFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRL1</accession>
    <name>A0A1J1GRL1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">U4/U6 small nuclear ribonucleoprotein PRP4, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">PRPF4</name>
        <name evidence="4" type="ORF">PGAL8A_00255000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527958.1">
        <property type="nucleotide sequence ID" value="XM_028671291.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRL1"/>
    <dbReference type="GeneID" id="39731078"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00255000"/>
    <dbReference type="OMA" id="LNEPICY"/>
    <dbReference type="OrthoDB" id="540662at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030621">
        <property type="term" value="F:U4 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017070">
        <property type="term" value="F:U6 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.110">
        <property type="entry name" value="Pre-mRNA processing factor 4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014906">
        <property type="entry name" value="PRP4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036285">
        <property type="entry name" value="PRP4-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19846:SF0">
        <property type="entry name" value="PRE-MRNA PROCESSING FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19846">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08799">
        <property type="entry name" value="PRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00500">
        <property type="entry name" value="SFM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158230">
        <property type="entry name" value="PRP4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Pre-mRNA processing factor 4 (PRP4)-like" evidence="3">
        <location>
            <begin position="52"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="389"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="431"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="516"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="330"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="334"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="605" mass="71612" checksum="1DFAE19126C54788" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRN5</accession>
    <name>A0A1J1GRN5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">60S ribosomal protein L23, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">RPL23</name>
        <name evidence="9" type="ORF">PGAL8A_00235300</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uL23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527769.1">
        <property type="nucleotide sequence ID" value="XM_028671080.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRN5"/>
    <dbReference type="GeneID" id="39730881"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00235300"/>
    <dbReference type="OMA" id="RLDHHKV"/>
    <dbReference type="OrthoDB" id="1267328at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000035">
        <property type="entry name" value="60S ribosomal protein L23a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01369_A">
        <property type="entry name" value="Ribosomal_uL23_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013025">
        <property type="entry name" value="Ribosomal_uL23-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_uL23/eL15/eS24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001014">
        <property type="entry name" value="Ribosomal_uL23_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005633">
        <property type="entry name" value="Ribosomal_uL23_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF011118">
        <property type="entry name" value="PRK14548.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11620">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L23A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00276">
        <property type="entry name" value="Ribosomal_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03939">
        <property type="entry name" value="Ribosomal_L23eN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="Ribosomal proteins S24e, L23 and L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00050">
        <property type="entry name" value="RIBOSOMAL_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL23 N-terminal" evidence="8">
        <location>
            <begin position="76"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="38"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="207" mass="23921" checksum="1751A7C829327FCC" modified="2017-02-15" version="1">MVEVSNDKKNTVEKKKAEDNKKSIKNNKNKMKVTINDKVVKKNEKKKLNEKQKGNEKKLKVKKTLDKNSDDKKKIKKVKFGGKNQKQKKIRTSIHFKRPKTLKLPRNPKCPRIVKSCFRKTLDKYGIIKHPLTSEKAMKKIEEINTLVFICDKRADKKKIKKAVKSLFGITCDKVNVLNRLSGDKKAYVRLSPEHDALEVANKIGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRR0</accession>
    <name>A0A1J1GRR0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">E1-E2 ATPase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00259800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528006.1">
        <property type="nucleotide sequence ID" value="XM_028671345.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731127"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00259800"/>
    <dbReference type="OMA" id="FYTFVTY"/>
    <dbReference type="OrthoDB" id="116380at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005388">
        <property type="term" value="F:P-type calcium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093:SF369">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="140"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="169"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="734"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="767"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1341"/>
            <end position="1361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1416"/>
            <end position="1438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1517"/>
            <end position="1535"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1669"/>
            <end position="1693"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="1699"/>
            <end position="1724"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="6">
        <location>
            <begin position="493"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="350"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="587"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="964"/>
            <end position="991"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1774" mass="213833" checksum="BFA67237764A1F4F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRX6</accession>
    <name>A0A1J1GRX6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">isoleucine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Isoleucyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00245100</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>tRNA(Ile) + L-isoleucine + ATP = L-isoleucyl-tRNA(Ile) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:9666"/>
            <dbReference type="Rhea" id="RHEA-COMP:9695"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78528"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.5"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.5" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527865.1">
        <property type="nucleotide sequence ID" value="XM_028671187.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRX6"/>
    <dbReference type="GeneID" id="39730979"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00245100"/>
    <dbReference type="OMA" id="EIIVIHK"/>
    <dbReference type="OrthoDB" id="1706657at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004822">
        <property type="term" value="F:isoleucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006428">
        <property type="term" value="P:isoleucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07961">
        <property type="entry name" value="Anticodon_Ia_Ile_ABEc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00818">
        <property type="entry name" value="IleRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000320">
        <property type="entry name" value="Isoleucine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000023">
        <property type="entry name" value="Isoleucyl-tRNA synthetase,cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033709">
        <property type="entry name" value="Anticodon_Ile_ABEc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002301">
        <property type="entry name" value="Ile-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023586">
        <property type="entry name" value="Ile-tRNA-ligase_type2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00392">
        <property type="entry name" value="ileS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42780:SF1">
        <property type="entry name" value="ISOLEUCINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42780">
        <property type="entry name" value="SOLEUCYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19302">
        <property type="entry name" value="DUF5915"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00984">
        <property type="entry name" value="TRNASYNTHILE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="11">
        <location>
            <begin position="68"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="12">
        <location>
            <begin position="810"/>
            <end position="998"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG95052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1219" mass="144905" checksum="0FAD33E1F9D986C5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS92</accession>
    <name>A0A1J1GS92_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Zinc finger protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00014000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528182.1">
        <property type="nucleotide sequence ID" value="XM_028671540.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS92"/>
    <dbReference type="GeneID" id="39728662"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00014000"/>
    <dbReference type="OMA" id="NSNNIWP"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16454">
        <property type="entry name" value="RING-H2_PA-TM-RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45969:SF69">
        <property type="entry name" value="FINGER DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G12190)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45969">
        <property type="entry name" value="RING ZINC FINGER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="991"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="403"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="661"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="98"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="403"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="419"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="661"/>
            <end position="679"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1038" mass="118586" checksum="3B5A70E78B62ECF8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSC6</accession>
    <name>A0A1J1GSC6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribonucleotide reductase small subunit, putative</fullName>
            <ecNumber evidence="2">1.17.4.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00392000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ribonucleoside diphosphate reductase small chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527037.1">
        <property type="nucleotide sequence ID" value="XM_028670268.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSC6"/>
    <dbReference type="GeneID" id="39732450"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00392000"/>
    <dbReference type="OMA" id="KENQFRW"/>
    <dbReference type="OrthoDB" id="2093646at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009263">
        <property type="term" value="P:deoxyribonucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01049">
        <property type="entry name" value="RNRR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.620.20:FF:000007">
        <property type="entry name" value="Ribonucleotide reductase small subunit,putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.620.20">
        <property type="entry name" value="Ribonucleotide Reductase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012348">
        <property type="entry name" value="RNR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033909">
        <property type="entry name" value="RNR_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000358">
        <property type="entry name" value="RNR_small_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23409">
        <property type="entry name" value="RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23409:SF18">
        <property type="entry name" value="RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SUBUNIT M2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00268">
        <property type="entry name" value="Ribonuc_red_sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="335" mass="40450" checksum="7CDA0628D8D6DC9D" modified="2017-02-15" version="1">MSKEYFHDQETLLEAQNNDDILTENKFRWVMFPIKYKTFWNYYKEIESLFWTAEDYNFDKDKQYLENIDKNMLIKLYELVCFYSLKDLHIYEEQALITSKMLDIIQIPEGRAFYGFQMCMENIHDEVYACIFETYIPDQKQKTVIINKVIQLDSVLKKQKWLTEIFETNIPFFNKLILLYISKVLFNGTLNILIGYCKENSILPCLCSVHEKIHRDEYLHGDFSVMCCNHLNNKLKYEHVLEYFKMAVELEYQFALEMLELNVLKIKKEQVRSFLEYLADTMLVNLKYPKHYNSKYPFLWPEIDKIVVNENHKTESVKKSDNIYGEKQILFDEDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSQ0</accession>
    <name>A0A1J1GSQ0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00404000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527157.1">
        <property type="nucleotide sequence ID" value="XM_028670401.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSQ0"/>
    <dbReference type="GeneID" id="39732570"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00404000"/>
    <dbReference type="OMA" id="FKFPGFW"/>
    <dbReference type="OrthoDB" id="366273at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="63" mass="7870" checksum="9C4E3E5FFCA19636" modified="2017-02-15" version="1" fragment="single">MAVPKKRRSLSKCRKRRNTIFFDKLVGNWLKRREWFFRHSYQKTVLPIEQEPEIFKFPGFWPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSQ4</accession>
    <name>A0A1J1GSQ4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00270600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000040">
        <property type="protein sequence ID" value="CRG95505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528314.1">
        <property type="nucleotide sequence ID" value="XM_028671686.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSQ4"/>
    <dbReference type="GeneID" id="39731237"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00270600"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="168" mass="19952" checksum="B7BB523159DCBCC7" modified="2017-02-15" version="1">MLYKFCFLFVIFIHLIINNCCKTFFIIFFYPPLMNIFTVFFPYNFLPFMGFLILSSFFFAIISSYISFRYSFSLFFISNINSINHFFFFHSSIFSLSLFNITFLLFLFISNMLTSSSKFSCILNSSTIFLKKYSFSFCNSSFIHSSNSVICISTKMFCINFSLFFLFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSV2</accession>
    <name>A0A1J1GSV2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00408800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527205.1">
        <property type="nucleotide sequence ID" value="XM_028670454.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSV2"/>
    <dbReference type="GeneID" id="39732618"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00408800"/>
    <dbReference type="OMA" id="YLNPYYC"/>
    <dbReference type="OrthoDB" id="372615at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="282"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="312"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="349" mass="42416" checksum="367AD5CCF1EA5C46" modified="2017-02-15" version="1">MDNLEKKKKNWNNVKNYILKKKEDTESFFANEELSDDLLNLLEKSNSTERKFIVSKNTNILKSNIDKVINIDVFNYIYEMITKKNEMRKEQMKLTLFSINRCVDFFNDFAFLIKIFCQINFSKSPNTINQNIYKFIFLWFLFLFITSFFTFYLRKFFILNIIPKKHHNLFSLFKVFKEIKSIDQNNLSILYFYDRIQKTYVIINKVFEDIPQFLLCLLYMILNGKDKFIIFNILYSIIYFIINTIDLGFNYPIIGTLNLFFSTYILDDSFVEYDAAPTNKIFCLYSFFVFFIWSLLALVTKRFVSIFWFPFIYFQFSILFLISIMFLLIFLYFYFHAKQSFYLNPYYCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSX7</accession>
    <name>A0A1J1GSX7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">P1/s1 nuclease, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00283500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the nuclease type I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528446.1">
        <property type="nucleotide sequence ID" value="XM_028671833.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSX7"/>
    <dbReference type="GeneID" id="39731368"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00283500"/>
    <dbReference type="OMA" id="LRYFIHI"/>
    <dbReference type="OrthoDB" id="441446at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11010">
        <property type="entry name" value="S1-P1_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.575.10">
        <property type="entry name" value="P1 Nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008947">
        <property type="entry name" value="PLipase_C/P1_nuclease_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003154">
        <property type="entry name" value="S1/P1nuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33146">
        <property type="entry name" value="ENDONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33146:SF10">
        <property type="entry name" value="STRAND-SPECIFIC NUCLEASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02265">
        <property type="entry name" value="S1-P1_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48537">
        <property type="entry name" value="Phospholipase C/P1 nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013334906" evidence="8">
        <location>
            <begin position="22"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG95638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="322" mass="38642" checksum="5FD4E3BDEEEC7928" modified="2017-02-15" version="1">MNRFIFSFILFNLLIFKKITCWSDEGHMLISAIAYRGLTDEERAVLDKIFMNYKEDNHFNHPVLGSIWPDHIKSFDYKYPNNERRIDAIDLMNGWHFINIPYNPLQVHIDLFYKYYYKKTEHGLSVLKYTFKTLKNINKKENHGTYFAYNFHLRFFIHIFGDLHQPLHTITFYNENFLEGDHGGNDISVRYNNNVDKLHYLCDTVFHSRAKKWPQITLDEIFNEADSLMRSYPREYFGNRLEKEMDEIEYLDFIVNESYSKAVDYIYSNFPHDSLNKETTYVLSNFFVINLKKLLNEQIVLGGYRLTRYLKIMIDNVPKDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTF5</accession>
    <name>A0A1J1GTF5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">DNA primase</fullName>
            <ecNumber evidence="17">2.7.7.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">PGAL8A_00197900</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalytic subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex - primosome/replisome) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ssDNA + n dNTP = ssDNA/pppdN(pdN)n-1 hybrid + (n-1) diphosphate.</text>
            <dbReference type="EC" id="2.7.7.102"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="16">Heterodimer of a catalytic subunit and a regulatory subunit, also known as the DNA primase complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 17">Belongs to the eukaryotic-type primase small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.-" evidence="17"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527397.1">
        <property type="nucleotide sequence ID" value="XM_028670668.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTF5"/>
    <dbReference type="GeneID" id="39730506"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00197900"/>
    <dbReference type="OMA" id="NVTRGFN"/>
    <dbReference type="OrthoDB" id="19606at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005658">
        <property type="term" value="C:alpha DNA polymerase:primase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04860">
        <property type="entry name" value="AE_Prim_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.920.10:FF:000004">
        <property type="entry name" value="DNA primase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.920.10">
        <property type="entry name" value="DNA primase, PRIM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002755">
        <property type="entry name" value="DNA_primase_S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014052">
        <property type="entry name" value="DNA_primase_ssu_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00335">
        <property type="entry name" value="primase_sml"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10536">
        <property type="entry name" value="DNA PRIMASE SMALL SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01896">
        <property type="entry name" value="DNA_primase_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56747">
        <property type="entry name" value="Prim-pol domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 17" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4 17" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0464">Manganese</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 18" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5 17" id="KW-0639">Primosome</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0804">Transcription</keyword>
    <keyword evidence="6 17 18" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00051714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00060314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00061726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU003514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="CRG94582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="450" mass="53337" checksum="368987514E3F6FA6" modified="2017-02-15" version="1">MDIINEIKDSVVNENDLIFYYRSLCPINDLYNWLNYKNDNKSKYSRLNDPNFFSKREFSFTCKKSDQGKEEIYMRWLSFNNAEEFKDKLLSNFVPIKFDIGAVYNYPVSQKDQKGDLFHPVQKELIFDIDMNDYDDIRTCCTDKKVCKLCWKFLTIAIVLLDTSLREDFSFQNILWVYSGRRGIHCWVCDESCRFYPTDARAALADYLNILSGADTKKKKVSIWGKEKYPMIERAFEICYKYFDILLEEQNFFKKGSSHVQKIIDYLPYASTKNLDPLKGMKINELKEFIDNNDFNSKQLFEKLSSIYGFLTPNDYFKKKETNPNIIIPSYIKEIVFHFTYPRLDINVSKEINHLLKSPFCIHNGTGRVCVPLDLKNIDNFNPQLVPTLKLLREQYDNPENADVSEEFRTSLKPYVDYFRHHFVENILISCVEKKKRISENSKYIDYNNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTI8</accession>
    <name>A0A1J1GTI8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter G family member 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ABCG2</name>
        <name evidence="10" type="ORF">PGAL8A_00297900</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528575.1">
        <property type="nucleotide sequence ID" value="XM_028671975.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTI8"/>
    <dbReference type="GeneID" id="39731512"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00297900"/>
    <dbReference type="OMA" id="NMQIVEF"/>
    <dbReference type="OrthoDB" id="184675at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03213">
        <property type="entry name" value="ABCG_EPDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001510">
        <property type="entry name" value="ABC transporter G family member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF139">
        <property type="entry name" value="PROTEIN SCARLET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="392"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="427"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="470"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="503"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="538"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="625"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="21"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG95767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="654" mass="74913" checksum="F9DF89494E770999" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTI9</accession>
    <name>A0A1J1GTI9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Coatamer beta subunit, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PGAL8A_00301400</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasmic vesicle</location>
            <location evidence="2">COPI-coated vesicle membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528610.1">
        <property type="nucleotide sequence ID" value="XM_028672015.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTI9"/>
    <dbReference type="GeneID" id="39731547"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00301400"/>
    <dbReference type="OMA" id="CTCAQER"/>
    <dbReference type="OrthoDB" id="10261439at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013041">
        <property type="entry name" value="Clathrin_app_Ig-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011710">
        <property type="entry name" value="Coatomer_bsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016460">
        <property type="entry name" value="COPB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029446">
        <property type="entry name" value="COPB1_appendage_platform_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10635">
        <property type="entry name" value="COATOMER SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10635:SF0">
        <property type="entry name" value="COATOMER SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07718">
        <property type="entry name" value="Coatamer_beta_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14806">
        <property type="entry name" value="Coatomer_b_Cpla"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49348">
        <property type="entry name" value="Clathrin adaptor appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="12">
        <location>
            <begin position="25"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer beta subunit C-terminal" evidence="13">
        <location>
            <begin position="903"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="domain" description="Coatomer beta subunit appendage platform" evidence="14">
        <location>
            <begin position="1069"/>
            <end position="1217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="253"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="253"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF07718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF14806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG95802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1235" mass="144025" checksum="D5E894F4A0FC9B28" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTN8</accession>
    <name>A0A1J1GTN8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PhIL1 interacting protein PIP2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00302700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528623.1">
        <property type="nucleotide sequence ID" value="XM_028672029.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTN8"/>
    <dbReference type="GeneID" id="39731560"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00302700"/>
    <dbReference type="OMA" id="TYYQYID"/>
    <dbReference type="OrthoDB" id="372049at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="345" mass="40607" checksum="132113E453DC854D" modified="2017-02-15" version="1">MEKEKNSSYMYQDTLKDLGEGLQNMETIKLNKNNKNYDFENINKGTDEPEENKYEKGNEKDNDNDNYYIKDSLNKILESNKDSYLKNLDYYKNNSKYKIDPCIHVEGVEEIENYIIKEKVYLTTYVQYIDVYEDTTNVEEDVEKEEVEYVEVPKYVTKYKPKIVTDIVEKTIEIPSGEEIKQPKYNTVDVPYIVPNIVENEILVVSKKIIQPEIEISNEVLEVEVEKYIPHLVPVNVYVPRYFGISAKTKGVAEESVKYVDLSQDQIDTLIKELNPHLDELKLFNENQLKRMDEYVKESQIQAKAHNFEPPQPQVITYDENGNCQSFDYSEFDRIKESYLKELAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTW8</accession>
    <name>A0A1J1GTW8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 17">O-phosphoseryl-tRNA(Sec) selenium transferase</fullName>
            <ecNumber evidence="5 17">2.9.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 17">Selenocysteine synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14 17">Selenocysteinyl-tRNA(Sec) synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="15 17">Sep-tRNA:Sec-tRNA synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">PGAL8A_00316900</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 17">Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16 17">
            <text>O-phospho-L-seryl-tRNA(Sec) + selenophosphate + H2O = L-selenocysteinyl-tRNA(Sec) + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:25041"/>
            <dbReference type="Rhea" id="RHEA-COMP:9743"/>
            <dbReference type="Rhea" id="RHEA-COMP:9947"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16144"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:78551"/>
            <dbReference type="ChEBI" id="CHEBI:78573"/>
            <dbReference type="EC" id="2.9.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 17 19">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 17">Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; selenocysteinyl-tRNA(Sec) from L-seryl-tRNA(Sec) (archaeal/eukaryal route): step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="17">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 17">Belongs to the SepSecS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.9.1.2" evidence="5 17"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528764.1">
        <property type="nucleotide sequence ID" value="XM_028672185.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTW8"/>
    <dbReference type="GeneID" id="39731702"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00316900"/>
    <dbReference type="OMA" id="MSHANDY"/>
    <dbReference type="OrthoDB" id="10263545at2759"/>
    <dbReference type="UniPathway" id="UPA00906">
        <property type="reaction ID" value="UER00898"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098621">
        <property type="term" value="F:O-phosphoseryl-tRNA(Sec) selenium transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001717">
        <property type="term" value="P:conversion of seryl-tRNAsec to selenocys-tRNAsec"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001514">
        <property type="term" value="P:selenocysteine incorporation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019872">
        <property type="entry name" value="Sec-tRNA_Se_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008829">
        <property type="entry name" value="SepSecS/SepCysS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03531">
        <property type="entry name" value="selenium_SpcS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12944:SF2">
        <property type="entry name" value="O-PHOSPHOSERYL-TRNA(SEC) SELENIUM TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12944">
        <property type="entry name" value="SOLUBLE LIVER ANTIGEN/LIVER PANCREAS ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05889">
        <property type="entry name" value="SepSecS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017689">
        <property type="entry name" value="SepSecS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="17" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 17" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10 17 19" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 17 19" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="12 17" id="KW-0711">Selenium</keyword>
    <keyword evidence="8 17 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 17 19" id="KW-0820">tRNA-binding</keyword>
    <feature type="binding site" evidence="18">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="319"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="408"/>
        </location>
        <ligand>
            <name>tRNA</name>
            <dbReference type="ChEBI" id="CHEBI:17843"/>
        </ligand>
        <ligandPart>
            <name>tRNA discriminator base</name>
        </ligandPart>
    </feature>
    <feature type="site" description="May act as a substrate filter by repelling compounds with a negatively charged alpha-carboxylate" evidence="19">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="19">
        <location>
            <position position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00032693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRNR" id="PIRNR017689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR017689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR017689-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="CRG95956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="584" mass="67346" checksum="F875640695DBDE67" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUB8</accession>
    <name>A0A1J1GUB8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00327100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000053">
        <property type="protein sequence ID" value="CRG96055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528863.1">
        <property type="nucleotide sequence ID" value="XM_028672296.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUB8"/>
    <dbReference type="GeneID" id="39731801"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00327100"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="276" mass="32990" checksum="C1A30149BF7FEB40" modified="2017-02-15" version="1">MKTLTLYLKITTFLLLIWMYQCFYNCDSYKTLIDKYILQTKNKLKYERILTEGNTEGKEQTNAQGGLKECPLDSEKKESMDPDKYKNPCDPRNRVNTPSLFERFNKKAKEIDPKLRNQELNIELSKISHDNVNPFSKIYERNIPDEGRQILILSNTQDHSELKKLLDVFKSEIRDNEAESEFKKEVRDNRTESESEKEMRDNKTESETEKEMKYNKTESESKNDMRDNITEFKWSNEMTDYETECESESENEMRENKKKKKKSNILKFLFCCCYNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUC6</accession>
    <name>A0A1J1GUC6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PIR-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00329800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528890.1">
        <property type="nucleotide sequence ID" value="XM_028672327.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUC6"/>
    <dbReference type="GeneID" id="39731828"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00329800"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="193"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="324" mass="36363" checksum="01A95D42452BDD73" modified="2017-02-15" version="1">MLNYSIIIFYLSFLINSINLKTEKFSTTWRILAEHQAAIPLIRTARSTSGMQGSLSRWLQSIEEEFFNNIEILRSNSTGTDDAIQWVKDKTKILLRALNSTENSHDKSLLSQTYSSWNNLTKSLLNFTLDFDFNDGLSTGNSSGSINLLNTSTPSSTSSSFSTSGVAQESSLGYRMSEACSGNFCGSTITTGLSLPFVIIGGLLFFAYLYKFTRIGSFLGRSDIKKERRKRKIYNGSMENIEDPYESSEETNSMNSILESSEETEAKKSRLESSEETEAKRSRLENSEETGDKSKFNSLLKAVGYKYRKIFPYIDSGLYGNENV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUE1</accession>
    <name>A0A1J1GUE1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00331600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528906.1">
        <property type="nucleotide sequence ID" value="XM_028672345.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUE1"/>
    <dbReference type="GeneID" id="39731846"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00331600"/>
    <dbReference type="OMA" id="IFCECLM"/>
    <dbReference type="OrthoDB" id="10255128at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1151" mass="137788" checksum="934A956E42E21544" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUF5</accession>
    <name>A0A1J1GUF5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Serine repeat antigen, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00330300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528895.1">
        <property type="nucleotide sequence ID" value="XM_028672332.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUF5"/>
    <dbReference type="GeneID" id="39731833"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00330300"/>
    <dbReference type="OrthoDB" id="10253408at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02619">
        <property type="entry name" value="Peptidase_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000169">
        <property type="entry name" value="Pept_cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013128">
        <property type="entry name" value="Peptidase_C1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000668">
        <property type="entry name" value="Peptidase_C1A_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12411">
        <property type="entry name" value="CYSTEINE PROTEASE FAMILY C1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00112">
        <property type="entry name" value="Peptidase_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00705">
        <property type="entry name" value="PAPAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00645">
        <property type="entry name" value="Pept_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00139">
        <property type="entry name" value="THIOL_PROTEASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0865">Zymogen</keyword>
    <feature type="domain" description="Peptidase C1A papain C-terminal" evidence="7">
        <location>
            <begin position="231"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="510"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="511"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="522"/>
            <end position="740"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="963" mass="109128" checksum="70C6611D06C34003" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUI2</accession>
    <name>A0A1J1GUI2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00311200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528707.1">
        <property type="nucleotide sequence ID" value="XM_028672123.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUI2"/>
    <dbReference type="GeneID" id="39731645"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00311200"/>
    <dbReference type="OMA" id="NLSYSCH"/>
    <dbReference type="OrthoDB" id="331240at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="464" mass="55420" checksum="17AF9B41588E1F21" modified="2017-02-15" version="1">MISQSGERLESERRSCCKCFITLLFLFILLLILRKQKEEDEIKNRSKVNLRQNENYNKDFSFGYIREISFLKYDSAIYISPNRKILPSITYINDYTLHVEGYDNILHNFENLSIKINEKNNNLYIFALSDNKNKNSICINKSYSDDFCAKINTVLVDKSLFKNMKIQSCDEQNSFCFFVFVQLKKNKCYNFVNLSYSCHENNMKNPNIFLINNYCYVLLASSKIPSVYEFIQFNLLKNENFNENTKTKDVEIITHFCGNLLNQIATIDSVNFRLLFVQQYIHINDKNLNNEVLGNETKFNKEINESEENEEKNTFNKYRNKEYNNNTLKFKINYYLTIIDMTSENKDIIEYVDYIKDKQEFSIFPPIHLAYDEQTNFYYIVQYENNGFLNFIFISPSKLSIYYTLKIREFYAGWLLNPNSEYDNKGLMLFGEYAPYEDELHIWNIINFQHNRYFVSIIKTYSNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUI7</accession>
    <name>A0A1J1GUI7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PI3K/PI4K catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00312000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528715.1">
        <property type="nucleotide sequence ID" value="XM_028672131.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731653"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00312000"/>
    <dbReference type="OMA" id="QVQYYEQ"/>
    <dbReference type="OrthoDB" id="381190at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="333"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="389"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="684"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="761"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="797"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="3505"/>
            <end position="3523"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="3645"/>
            <end position="3664"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="3">
        <location>
            <begin position="2848"/>
            <end position="3235"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="521"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3322"/>
            <end position="3349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="4094" mass="499934" checksum="CB0E7B44E34607A5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUM3</accession>
    <name>A0A1J1GUM3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00240500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527821.1">
        <property type="nucleotide sequence ID" value="XM_028671139.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730933"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00240500"/>
    <dbReference type="OMA" id="PIEFMFK"/>
    <dbReference type="OrthoDB" id="381178at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002093">
        <property type="entry name" value="BRCA2_repeat"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50138">
        <property type="entry name" value="BRCA2_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2645" mass="316443" checksum="11389EF37B420E33" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUT3</accession>
    <name>A0A1J1GUT3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Origin recognition complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00246300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527877.1">
        <property type="nucleotide sequence ID" value="XM_028671202.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUT3"/>
    <dbReference type="GeneID" id="39730991"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00246300"/>
    <dbReference type="OMA" id="QRCIYTI"/>
    <dbReference type="OrthoDB" id="343623at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005664">
        <property type="term" value="C:nuclear origin of replication recognition complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016527">
        <property type="entry name" value="ORC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12087">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12087:SF0">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="590"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="695"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="597"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="703"/>
            <end position="714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="891" mass="106117" checksum="5F183891F1667B54" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUX2</accession>
    <name>A0A1J1GUX2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">40S ribosomal protein S18, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00352900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the universal ribosomal protein uS13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529116.1">
        <property type="nucleotide sequence ID" value="XM_028672578.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUX2"/>
    <dbReference type="GeneID" id="39732059"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00352900"/>
    <dbReference type="OMA" id="SYKGVRH"/>
    <dbReference type="OrthoDB" id="1702480at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.50:FF:000002">
        <property type="entry name" value="40S ribosomal protein S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.910.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.910.10">
        <property type="entry name" value="30s ribosomal protein s13, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01315">
        <property type="entry name" value="Ribosomal_uS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027437">
        <property type="entry name" value="Rbsml_uS13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001892">
        <property type="entry name" value="Ribosomal_uS13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_uS13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018269">
        <property type="entry name" value="Ribosomal_uS13_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003140">
        <property type="entry name" value="PRK04053.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S13/40S RIBOSOMAL PROTEIN S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871:SF3">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00416">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002134">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="S13-like H2TH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00646">
        <property type="entry name" value="RIBOSOMAL_S13_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50159">
        <property type="entry name" value="RIBOSOMAL_S13_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="134"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="156" mass="17880" checksum="A1B270C3AD429AF7" modified="2017-02-15" version="1">MSLQVIDQNEFQHILRILNTNVDGKEKVIIALTAIKGIGKRMATVICKQANVNPTKRAGELTKEEISNIVSIMNAPTQFKIPDWFLNRRKDLKEGKNLHVIANQLDSYLREDLERMKKIRLHRGLRHHWGLRVRGQHTKTTGRRGRTVGVSKKKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUZ8</accession>
    <name>A0A1J1GUZ8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">threonine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Threonyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ThrRS</name>
        <name evidence="14" type="ORF">PGAL8A_00352700</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>tRNA(Thr) + L-threonine + ATP = L-threonyl-tRNA(Thr) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24624"/>
            <dbReference type="Rhea" id="RHEA-COMP:9670"/>
            <dbReference type="Rhea" id="RHEA-COMP:9704"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78534"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.3" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529114.1">
        <property type="nucleotide sequence ID" value="XM_028672575.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUZ8"/>
    <dbReference type="GeneID" id="39732057"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00352700"/>
    <dbReference type="OMA" id="WYADGMY"/>
    <dbReference type="OrthoDB" id="5423599at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004829">
        <property type="term" value="F:threonine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006435">
        <property type="term" value="P:threonyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01667">
        <property type="entry name" value="TGS_ThrRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00860">
        <property type="entry name" value="ThrRS_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00771">
        <property type="entry name" value="ThrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.800:FF:000031">
        <property type="entry name" value="Threonine-tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.980.10:FF:000005">
        <property type="entry name" value="Threonyl-tRNA synthetase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.980.10">
        <property type="entry name" value="Threonyl-trna Synthetase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00184">
        <property type="entry name" value="Thr_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002320">
        <property type="entry name" value="Thr-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047246">
        <property type="entry name" value="ThrRS_anticodon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033728">
        <property type="entry name" value="ThrRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00418">
        <property type="entry name" value="thrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451:SF46">
        <property type="entry name" value="THREONINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451">
        <property type="entry name" value="THREONINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01047">
        <property type="entry name" value="TRNASYNTHTHR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="ThrRS/AlaRS common domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012723831" description="threonine--tRNA ligase" evidence="12">
        <location>
            <begin position="18"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="13">
        <location>
            <begin position="396"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="659"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="100"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG96309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="847" mass="99562" checksum="087817F2BC316172" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV20</accession>
    <name>A0A1J1GV20_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00329900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528891.1">
        <property type="nucleotide sequence ID" value="XM_028672328.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV20"/>
    <dbReference type="GeneID" id="39731829"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00329900"/>
    <dbReference type="OrthoDB" id="10687359at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1167" mass="135227" checksum="F60B4FB92C53443A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVA9</accession>
    <name>A0A1J1GVA9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">acylphosphatase</fullName>
            <ecNumber evidence="2 5">3.6.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00338400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4 5">
            <text>an acyl phosphate + H2O = a carboxylate + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="EC" id="3.6.1.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the acylphosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.7" evidence="2 5"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528971.1">
        <property type="nucleotide sequence ID" value="XM_028672416.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVA9"/>
    <dbReference type="GeneID" id="39731914"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00338400"/>
    <dbReference type="OMA" id="WVRNTSH"/>
    <dbReference type="OrthoDB" id="7961613at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003998">
        <property type="term" value="F:acylphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.100:FF:000054">
        <property type="entry name" value="Acylphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020456">
        <property type="entry name" value="Acylphosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001792">
        <property type="entry name" value="Acylphosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036046">
        <property type="entry name" value="Acylphosphatase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017968">
        <property type="entry name" value="Acylphosphatase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10029">
        <property type="entry name" value="ACYLPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10029:SF3">
        <property type="entry name" value="ACYLPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00708">
        <property type="entry name" value="Acylphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00112">
        <property type="entry name" value="ACYLPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54975">
        <property type="entry name" value="Acylphosphatase/BLUF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00150">
        <property type="entry name" value="ACYLPHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51160">
        <property type="entry name" value="ACYLPHOSPHATASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acylphosphatase-like" evidence="7">
        <location>
            <begin position="38"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="129" mass="15260" checksum="A03772F1D2334944" modified="2017-02-15" version="1">MRFSNIFYSFLLFHQRKKLSNKNYFLRKIYNSSKMIYSFDFEVFGKVQGVFFRKYTKQEADKLNIKGYVQNTDKNTVIGKAESDKKESLEKFKFFLTNVGSPSSKIDKCIITDEKTINSFSSTNFFIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVY4</accession>
    <name>A0A1J1GVY4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Mitochondrial ribosomal protein S9, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00364700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529227.1">
        <property type="nucleotide sequence ID" value="XM_028672701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVY4"/>
    <dbReference type="GeneID" id="39732177"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00364700"/>
    <dbReference type="OMA" id="IHNDMEW"/>
    <dbReference type="OrthoDB" id="10254627at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000754">
        <property type="entry name" value="Ribosomal_uS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020574">
        <property type="entry name" value="Ribosomal_uS9_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569">
        <property type="entry name" value="RIBOSOMAL PROTEIN S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US9M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00380">
        <property type="entry name" value="Ribosomal_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00360">
        <property type="entry name" value="RIBOSOMAL_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="93"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="291" mass="34212" checksum="D50F65E592F293BD" modified="2017-02-15" version="1">MKWISRLVGTTKRYNNNVKKNIFIENICQYSSKNEINNKKKNEYILSLDEALYLSKEMGIKTTTEVQKIIMKSPPFSSDASPFIIENFLSNIKKDDLDEIKKIDEKIEDLEKKKDEKKKEDTLNNLHINEHENKNDNIVNKFLINNFNKKRSKTFFHDNKEWLEESEGIGTNKRSCAYVYIKRGSGVVKINNEEDLYIRWPYFYNRIDVMEPFYLTNTACIYDVFIKLKGGGISGQSKAARLAIGRALLNACPLIYNDLVQNDILYEDMRQKFPKMPGRKKSRSMKQWSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW69</accession>
    <name>A0A1J1GW69_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Nucleolar preribosomal assembly protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00373500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529315.1">
        <property type="nucleotide sequence ID" value="XM_028672798.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW69"/>
    <dbReference type="GeneID" id="39732265"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00373500"/>
    <dbReference type="OMA" id="AWEPYHR"/>
    <dbReference type="OrthoDB" id="10267436at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012972">
        <property type="entry name" value="NLE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF0">
        <property type="entry name" value="NOTCHLESS PROTEIN HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08154">
        <property type="entry name" value="NLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="NLE" evidence="7">
        <location>
            <begin position="12"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="114"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="156"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="350"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="477"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="519"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="587"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="227"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="254"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="296"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="620" mass="71095" checksum="DF0C6A17CE442B27" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW76</accession>
    <name>A0A1J1GW76_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00437500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529596.1">
        <property type="nucleotide sequence ID" value="XM_028673111.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732907"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00437500"/>
    <dbReference type="OrthoDB" id="372328at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="428"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="467"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="700"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1960"/>
            <end position="1992"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="770"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="435"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="467"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="478"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="539"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="652"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1972"/>
            <end position="1990"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2262" mass="268344" checksum="AC06E8BD2427241E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW77</accession>
    <name>A0A1J1GW77_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00427100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529495.1">
        <property type="nucleotide sequence ID" value="XM_028672998.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW77"/>
    <dbReference type="GeneID" id="39732803"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00427100"/>
    <dbReference type="OrthoDB" id="10484915at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="335" mass="40199" checksum="1DA84B7C1DB3C6D5" modified="2017-02-15" version="1">MIHLILQVFSFNFTSVLCFSLLIFIILFLIYGKHKYIYKFINNNIYKKKYNIKFSKYNGYNLNQLNKRVNNSTHNKEDEYLLYKKKFLLNRKNKFLKRIKTKLFHNSLSKYNFKYKLNFYVCNVTKKKKTKLIHSLSNEKKKKKKMNIKFNNTNENNTTQVTLIDEKNAPSTIFNYDKNDEIKNMLVDLKEICDNLKIFVENNILKEQKKANLFVATNMKNEKLLKKEINTLSNNQELNCENINNCVHKKLDKENMILHKNEIESCICNLFKIYKEIELLKDINTYTYVCMLNEYCNFLLKFKVLDYLDICRNNNIANEVSTNLIQKVIIYVWGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWA8</accession>
    <name>A0A1J1GWA8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00430300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529527.1">
        <property type="nucleotide sequence ID" value="XM_028673034.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732835"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00430300"/>
    <dbReference type="OMA" id="YHDETEH"/>
    <dbReference type="OrthoDB" id="386500at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="446"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1165"/>
            <end position="1210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="446"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="457"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1567" mass="186438" checksum="FC01BFCCD5C5FDF1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWA9</accession>
    <name>A0A1J1GWA9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00434000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529562.1">
        <property type="nucleotide sequence ID" value="XM_028673072.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWA9"/>
    <dbReference type="GeneID" id="39732872"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00434000"/>
    <dbReference type="OMA" id="YLPYCIQ"/>
    <dbReference type="OrthoDB" id="368870at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="208" mass="25193" checksum="D8A2B437C07D6A42" modified="2017-02-15" version="1">MNYDKINLFSENFDMKYVLEEIEKNFDKRKHLLCDINNVVLNSERKKKFIDNYEEKLIDKQIKIIINTKMNYKKLNNINYVKYYLPYCIQPKTNNTNLCLTKNIHNKNTKQSILRELNTKKKEVEFKIKHFIKKYTGRYKKKSILHKQISQLFKEKSKIELYIKNKKNTKINFNKVIGDIAFFDHNINLLLENVIFNSCSIIFIKKYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWE9</accession>
    <name>A0A1J1GWE9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ribosomal RNA-processing protein 8</fullName>
            <ecNumber evidence="8">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00438000</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Probable methyltransferase required to silence rDNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
            <location evidence="1 8">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the methyltransferase superfamily. RRP8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529602.1">
        <property type="nucleotide sequence ID" value="XM_028673117.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWE9"/>
    <dbReference type="GeneID" id="39732913"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00438000"/>
    <dbReference type="OMA" id="YVTACNI"/>
    <dbReference type="OrthoDB" id="10258825at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2150">
        <property type="entry name" value="Ribosomal RNA-processing protein 8, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007823">
        <property type="entry name" value="RRP8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042036">
        <property type="entry name" value="RRP8_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12787">
        <property type="entry name" value="RIBOSOMAL RNA-PROCESSING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12787:SF0">
        <property type="entry name" value="RIBOSOMAL RNA-PROCESSING PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05148">
        <property type="entry name" value="Methyltransf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6 8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="83"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="102"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG96799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="418" mass="49576" checksum="9E212169CF7487C1" modified="2017-02-15" version="1">MEDKNIKVKLKNKQNNNSLKKKENKNNLYNTVMKQSKKKISKIIKKKKRFYNKFKIENTNSCVHNKISKNEKAINDNLINKNPKNGIIKDISKKKKSTKSHSNTENKSKEIKHPDMNKRKNIIYKNLIKNNEKVSKSTKIKKEENKKFPNINTLYKDTVNKNFYYHMNKKNEDPCSSSNLEKNKQKYKKKKKIDRNPEDIVNSSLFRYINEYMYTNKSIVVEKKLNETKNIFNIYHLGYKNQKEKWPNNPVNVIINYLKKNFTKHNNIGDLGCGEAEIAKTLNDWLIDSFDLIKFNEYVTACNITKLEKPDDSYDCLILSLSLMNTDWPKIIFESVRCLKKKGTLIIAEVVSRFKNYKAFMKFMNNVGFKLSKKVNLDDFFFVFFFENNKKDNSTYILSEKRVKKVSELLTPCIYKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWK8</accession>
    <name>A0A1J1GWK8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Rap guanine nucleotide exchange factor, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">EPAC</name>
        <name evidence="4" type="ORF">PGAL8A_00289000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528501.1">
        <property type="nucleotide sequence ID" value="XM_028671894.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731423"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00289000"/>
    <dbReference type="OrthoDB" id="417078at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23011">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-BINDING DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23011:SF28">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-BINDING DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="3">
        <location>
            <begin position="1859"/>
            <end position="1960"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="3">
        <location>
            <begin position="2160"/>
            <end position="2270"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="3">
        <location>
            <begin position="2302"/>
            <end position="2421"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="3">
        <location>
            <begin position="2939"/>
            <end position="3043"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="3">
        <location>
            <begin position="3066"/>
            <end position="3172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="667"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="981"/>
            <end position="1109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1993"/>
            <end position="2035"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2592"/>
            <end position="2615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3247"/>
            <end position="3332"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="427"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2487"/>
            <end position="2514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="676"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="981"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1013"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1059"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1069"/>
            <end position="1092"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1093"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2001"/>
            <end position="2027"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="3253"/>
            <end position="3278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="3288"/>
            <end position="3332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3332" mass="395507" checksum="C33C00ECB877E27A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWR2</accession>
    <name>A0A1J1GWR2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00449200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000073">
        <property type="protein sequence ID" value="CRG96911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529714.1">
        <property type="nucleotide sequence ID" value="XM_028673241.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWR2"/>
    <dbReference type="GeneID" id="39733025"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00449200"/>
    <dbReference type="OrthoDB" id="385690at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="419" mass="50238" checksum="CCCCACCB5522D661" modified="2017-02-15" version="1">MVENENEEITDIESVFSDYSYDTDTTASINNSDNEESDGNIQIKIKRAIENRILEENKKKRKIFNFEKKGYKLKTRKLEIFKNRNIKKSIENIENFNSSNIKSLSIDDIYNKREKYEDTYSKKKKKKKKIFLKNENIEIYEIESLFQFNIVENKSTSSLKDTQLVKMSKKLNKNHFNFLTCISNDRSSLSVTCKTLKTVEIIQKKKTPVIFFQGIMHKMIDIIEKKLSDDYEIIKIEDIFGERLNYFFLILILKKNFKLIKKEIFTFCDSMVDKYAIKILINSVNNPDENILLINTSHLEYNISLNKEKKFQFRHYFIDILQNTKDRKKKKKMNTIILCDNFDYTNDDIKKNDFLFNILDNWDTLNFSENFQNSRNCLLNKNTCNKFFFFKSRKIFHRIYRIKNNSNNCSNYIPFKKID</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWS9</accession>
    <name>A0A1J1GWS9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00450800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000081">
        <property type="protein sequence ID" value="CRG96927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529730.1">
        <property type="nucleotide sequence ID" value="XM_028673259.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733041"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00450800"/>
    <dbReference type="OrthoDB" id="348930at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="776"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="391"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="455"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="589"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="736"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1008"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1634"/>
            <end position="1686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="391"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="417"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="455"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="602"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="737"/>
            <end position="768"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1828" mass="214636" checksum="583613C86AA9924A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWT5</accession>
    <name>A0A1J1GWT5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00458100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529804.1">
        <property type="nucleotide sequence ID" value="XM_028673342.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWT5"/>
    <dbReference type="GeneID" id="39733114"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00458100"/>
    <dbReference type="OMA" id="YNREDMI"/>
    <dbReference type="OrthoDB" id="370440at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012385032" evidence="2">
        <location>
            <begin position="21"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="49"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="600" mass="72395" checksum="9CD3128D3E34E4A7" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWV5</accession>
    <name>A0A1J1GWV5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fam-i protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00450500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000079">
        <property type="protein sequence ID" value="CRG96924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529727.1">
        <property type="nucleotide sequence ID" value="XM_028673256.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWV5"/>
    <dbReference type="GeneID" id="39733038"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00450500"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="94" mass="10456" checksum="93D8FF9E1313A0AD" modified="2017-02-15" version="1">MDLKLSDATSIDSNDNLNGGNSTVEFAHREIEGATVSIPENPLYDDLDLRDSIQNPSEDINLDSTSSTNLHHKNLLSIFHLVMIIISFLRFAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWW0</accession>
    <name>A0A1J1GWW0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">hydroxyethylthiazole kinase</fullName>
            <ecNumber evidence="4">2.7.1.50</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00461300</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-(2-hydroxyethyl)-4-methylthiazole + ATP = 4-methyl-5-(2-phosphooxyethyl)-thiazole + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24212"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17957"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58296"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; thiamine diphosphate biosynthesis; 4-methyl-5-(2-phosphoethyl)-thiazole from 5-(2-hydroxyethyl)-4-methylthiazole: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.50" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529836.1">
        <property type="nucleotide sequence ID" value="XM_028673378.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWW0"/>
    <dbReference type="GeneID" id="39733146"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00461300"/>
    <dbReference type="OMA" id="KRPLVHN"/>
    <dbReference type="OrthoDB" id="4994at2759"/>
    <dbReference type="UniPathway" id="UPA00060">
        <property type="reaction ID" value="UER00139"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004417">
        <property type="term" value="F:hydroxyethylthiazole kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01170">
        <property type="entry name" value="THZ_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000417">
        <property type="entry name" value="Hyethyz_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006830">
        <property type="entry name" value="PRK09355.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02110">
        <property type="entry name" value="HK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000513">
        <property type="entry name" value="Thz_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01099">
        <property type="entry name" value="HYETHTZKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="5 12" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG97033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="308" mass="34558" checksum="B86B265606317AF0" modified="2017-02-15" version="1">MSIFKVHLKKLNCNIKNRFFSSLNKLNNVKDFHDEIIKCIEKVKEVNPLVHCITNRVTTEKMANSLLAFGSSPAMIDNPKEVEEFAKVSSCTYFNLGLHTSQIDNINVLEKLRKEIMKDDLILIIDPIAVGATKYRTNIIKEIILKCKPNVIKGNVAEIFYLDKEEFVGKGVDSNNSSLNEADIIRSARNVALKYNCTVVVTSKCDYIVSKCSHNIAKINCDLKILTKITGSGCSVGALCAAATSVNSQNSFIACTSATLIYKLAAFKAYKKETYPGSLSHKIIDYIYYYSNNPQFLNFQVLDFYKII</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWW2</accession>
    <name>A0A1J1GWW2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Amino acid transporter, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00453100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529754.1">
        <property type="nucleotide sequence ID" value="XM_028673285.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733064"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00453100"/>
    <dbReference type="OMA" id="DHLCSIF"/>
    <dbReference type="OrthoDB" id="294541at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16189:SF3">
        <property type="entry name" value="AMINO ACID TRANSPORTER TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16189">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 104-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="129"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="230"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="529"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="561"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="594"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="622"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="2153"/>
            <end position="2173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2005"/>
            <end position="2032"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1251"/>
            <end position="1311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2013"/>
            <end position="2029"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2174" mass="255897" checksum="6D16939F430A9F79" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWZ5</accession>
    <name>A0A1J1GWZ5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00274000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528352.1">
        <property type="nucleotide sequence ID" value="XM_028671728.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWZ5"/>
    <dbReference type="GeneID" id="39731272"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00274000"/>
    <dbReference type="OMA" id="YHGKIIT"/>
    <dbReference type="OrthoDB" id="405860at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="186" mass="21755" checksum="87A3D664710AB646" modified="2017-02-15" version="1">MSSGFLNLTKRKLGGNHIYLGKWHDFNQWKYIAPTNLLNIIRPVEQTKSVTADLYKHNDVLSYLNDVSHGKIITIDDLHSNNLKKNKIRGTGFHGPERTDVFRLILYNRLKQKQPQRIVPDIQEMKDANKLEVSIVWFLWSFVIIYCSMCIYGSNYIIKNKSTSFPWMPKRTDGSKGEGPMFWFLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX42</accession>
    <name>A0A1J1GX42_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00461900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529842.1">
        <property type="nucleotide sequence ID" value="XM_028673384.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733152"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00461900"/>
    <dbReference type="OMA" id="EKVMNRD"/>
    <dbReference type="OrthoDB" id="392606at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24417:SF7">
        <property type="entry name" value="CHROMATIN MODIFICATION-RELATED PROTEIN EAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24417">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE LMTK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="601"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1083"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1763"/>
            <end position="1826"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="61"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="624"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1763"/>
            <end position="1780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1788"/>
            <end position="1801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1802"/>
            <end position="1815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1816"/>
            <end position="1826"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1857" mass="223756" checksum="E5AFAD4F67EC99CA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXF2</accession>
    <name>A0A1J1GXF2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00455400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529777.1">
        <property type="nucleotide sequence ID" value="XM_028673313.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXF2"/>
    <dbReference type="GeneID" id="39733087"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00455400"/>
    <dbReference type="OMA" id="LDWRNAG"/>
    <dbReference type="OrthoDB" id="360650at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="205" mass="24490" checksum="F6D37ACDCC6E80BE" modified="2017-02-15" version="1">MSKKLDILKAKLPKAPTGRRPIGYRGNHQHGKSLYDPVYPTTKIPTSLIPRYPLDWRNGGRFLLCVGLRRIENRIINKMKESQDFNICECNICNDNCIKIYNRCLCAWFCKYKYRHMYKCDNLLINYKGEIKTEKPIFTLKREVAKKNLKKSVEYIYNNKTNLYEIKEENNIYKKFYQKIQEENNNPKDNFYDSDSDITDSEEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXH8</accession>
    <name>A0A1J1GXH8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00485500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530078.1">
        <property type="nucleotide sequence ID" value="XM_028673647.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXH8"/>
    <dbReference type="GeneID" id="39733388"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00485500"/>
    <dbReference type="OMA" id="HNSYCAY"/>
    <dbReference type="OrthoDB" id="363639at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2130.30">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="517" mass="61273" checksum="81071E155FB2FA41" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXL9</accession>
    <name>A0A1J1GXL9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcription elongation factor SPT4, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SPT4</name>
        <name evidence="7" type="ORF">PGAL8A_00489300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SPT4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530116.1">
        <property type="nucleotide sequence ID" value="XM_028673689.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXL9"/>
    <dbReference type="GeneID" id="39733426"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00489300"/>
    <dbReference type="OMA" id="CYAISVV"/>
    <dbReference type="OrthoDB" id="248751at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032044">
        <property type="term" value="C:DSIF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140673">
        <property type="term" value="P:transcription elongation-coupled chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07973">
        <property type="entry name" value="Spt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.210:FF:000004">
        <property type="entry name" value="Transcription elongation factor SPT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029040">
        <property type="entry name" value="RPABC4/Spt4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009287">
        <property type="entry name" value="Spt4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022800">
        <property type="entry name" value="Spt4/RpoE2_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038510">
        <property type="entry name" value="Spt4_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12882">
        <property type="entry name" value="SUPPRESSOR OF TY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12882:SF1">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR SPT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06093">
        <property type="entry name" value="Spt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01389">
        <property type="entry name" value="Spt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63393">
        <property type="entry name" value="RNA polymerase subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="Spt4/RpoE2 zinc finger" evidence="6">
        <location>
            <begin position="42"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="132" mass="15245" checksum="10D5F937D224D639" modified="2017-02-15" version="1">MTTSKGRKKSDMKKNDESFAEQKDLPKKSKNNLQEDKAVLKLRACLSCRLLKTEAEFYQNGCNNCKFLQMTGDRHRIHDCTTENFHGFIAITNPNKSWMAQYNDLSKYVPGFYALQIVGELPESIRDLKANY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXM6</accession>
    <name>A0A1J1GXM6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">mRNA methyltransferase, putative</fullName>
            <ecNumber evidence="5">2.1.1.62</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00457200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MT-A70-like family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.62" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529795.1">
        <property type="nucleotide sequence ID" value="XM_028673332.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXM6"/>
    <dbReference type="GeneID" id="39733105"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00457200"/>
    <dbReference type="OMA" id="EYISWFE"/>
    <dbReference type="OrthoDB" id="14833at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036396">
        <property type="term" value="C:RNA N6-methyladenosine methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016422">
        <property type="term" value="F:mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045123">
        <property type="entry name" value="METTL14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007757">
        <property type="entry name" value="MT-A70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13107">
        <property type="entry name" value="N6-ADENOSINE-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13107:SF0">
        <property type="entry name" value="N6-ADENOSINE-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05063">
        <property type="entry name" value="MT-A70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51143">
        <property type="entry name" value="MT_A70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51592">
        <property type="entry name" value="SAM_MTA70L_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="457"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="457"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="489"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="526"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="901" mass="104577" checksum="021CB5E02B300BE4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY58</accession>
    <name>A0A1J1GY58_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Zinc finger protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00506500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530293.1">
        <property type="nucleotide sequence ID" value="XM_028673885.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY58"/>
    <dbReference type="GeneID" id="39733598"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00506500"/>
    <dbReference type="OrthoDB" id="368623at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="5">
        <location>
            <begin position="54"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="244" mass="28934" checksum="83F3140441B09D03" modified="2017-02-15" version="1">MNDRLSRDLTKIFMDKREIAKEEIDPRKNWLKRILINNNSIDLKNFLKASTFKKKEVNYCINCKGVIKQSYYLNAKKSFCDLCEEVFCMYCVKSIDLMKDTKLKYIKIRLCKNCFIYINELKYIIHPNLSIDKKAIDLENIFNKISSCYTTICGNISQLNGLILLCENNKEFLDDFKKEIKHLTEKIEEDVEFLNRMKKKNNFITDNTLILNKMSKNLFLYLKIIRSKIMPCAVEVLKKSKELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY59</accession>
    <name>A0A1J1GY59_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-i protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00497200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000098">
        <property type="protein sequence ID" value="CRG97397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530199.1">
        <property type="nucleotide sequence ID" value="XM_028673781.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY59"/>
    <dbReference type="GeneID" id="39733505"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00497200"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="286"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="481" mass="59401" checksum="8ADD600E8DA1CBB7" modified="2017-02-15" version="1">MNLNLSDAINIDSNKRINEGDSTADFAHRVIKDATVSIPENPLYDDSNLRDTIQNPSEDINLDLAPSINLLRKKPLSIFQLVIIIISFLRFVRAYSPRLRAKHKERVMLQNKWDKRDKKMKDDWEKMEKKWNERKQKENREKEKLNKKKEERKKKTNNEMEEFNRRWNGEKERENDSEDKSLKILNPSSVSGKNIESLNEEQYHIYLDEQSTSQACNKTFKKKKKNNMPSNNKGEKLKGKFSNKLKSELELEKKRREELFRQVVELDEKWKKYEELCIMRSEWKKEERKKLEEGRRERRKKHEKKMLKENEERKKRMIEKNKEWENRMIEKNKKWENRMIEKNKEWEKRMLKEKKEMDEWEKRMLKEKKGNEKWEKRILKEKEEGEKIMQEEKEEWEKEMLKEKEEWEKKMLKEKEEWEKKMLKEKEKLEKSIMEKNEKWKREENMKVNDEEIKLNLKWKKELDKIKAKEGKKIKKIQIHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYA0</accession>
    <name>A0A1J1GYA0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA-directed RNA polymerase alpha chain, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00503700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530265.1">
        <property type="nucleotide sequence ID" value="XM_028673853.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYA0"/>
    <dbReference type="GeneID" id="39733570"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00503700"/>
    <dbReference type="OMA" id="PHIGHEE"/>
    <dbReference type="OrthoDB" id="360088at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.12">
        <property type="entry name" value="DNA-directed RNA polymerase, insert domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="entry name" value="RNA polymerase, RBP11-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011262">
        <property type="entry name" value="DNA-dir_RNA_pol_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011263">
        <property type="entry name" value="DNA-dir_RNA_pol_RpoA/D/Rpb3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036643">
        <property type="entry name" value="RNApol_insert_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01000">
        <property type="entry name" value="RNA_pol_A_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00662">
        <property type="entry name" value="RPOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56553">
        <property type="entry name" value="Insert subdomain of RNA polymerase alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="RBP11-like subunits of RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase RpoA/D/Rpb3-type" evidence="3">
        <location>
            <begin position="254"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="617" mass="73195" checksum="0C0C40CE32F08700" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYG8</accession>
    <name>A0A1J1GYG8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Small ribosomal subunit protein uS2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RPS2</name>
        <name evidence="8" type="ORF">PGAL8A_00486000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S). Interacts with ribosomal protein S21.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6 7">Belongs to the universal ribosomal protein uS2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530083.1">
        <property type="nucleotide sequence ID" value="XM_028673652.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYG8"/>
    <dbReference type="GeneID" id="39733393"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00486000"/>
    <dbReference type="OMA" id="QCHLGAK"/>
    <dbReference type="OrthoDB" id="414863at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01425">
        <property type="entry name" value="RPS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10490:FF:000012">
        <property type="entry name" value="40S ribosomal protein SA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03015">
        <property type="entry name" value="Ribosomal_S2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001865">
        <property type="entry name" value="Ribosomal_uS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018130">
        <property type="entry name" value="Ribosomal_uS2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027498">
        <property type="entry name" value="Ribosomal_uS2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005707">
        <property type="entry name" value="Ribosomal_uS2_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023591">
        <property type="entry name" value="Ribosomal_uS2_flav_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01012">
        <property type="entry name" value="uS2_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11489">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN SA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00318">
        <property type="entry name" value="Ribosomal_S2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00395">
        <property type="entry name" value="RIBOSOMALS2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52313">
        <property type="entry name" value="Ribosomal protein S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00962">
        <property type="entry name" value="RIBOSOMAL_S2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00963">
        <property type="entry name" value="RIBOSOMAL_S2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="263" mass="29921" checksum="5952A2A0FB79E4C6" modified="2017-02-15" version="1">MSNKKTLSSKEESIAKMLICKVHIGTKNLENKMKRYVYTRAKDGVHIINLAKTYEKLQLAARIIVAISNPADVVVVSARPFGSRAVLKFAQYTGAQAIAGRWTPGMLTNQIIQKFTEPRLLIVTDPRTDAQPVKESSYANIPVIALCDSDSPLEHVDIAIPCNNKGKESIALMYWLLAQEVLYLKGTLKRSEPWNVMVDMFLWRDPEQFELKNLANEENAATAPHLVENQFATEAPYEEWNKKEEWNDNTNEDWKNPITADEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYQ9</accession>
    <name>A0A1J1GYQ9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Bromodomain protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00527600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530501.1">
        <property type="nucleotide sequence ID" value="XM_028674116.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYQ9"/>
    <dbReference type="GeneID" id="39733809"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00527600"/>
    <dbReference type="OMA" id="NIYDAGK"/>
    <dbReference type="OrthoDB" id="21449at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04369">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018359">
        <property type="entry name" value="Bromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052442">
        <property type="entry name" value="Env_Response_Regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46136:SF1">
        <property type="entry name" value="TRANSCRIPTION FACTOR GTE11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46136">
        <property type="entry name" value="TRANSCRIPTION FACTOR GTE8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00633">
        <property type="entry name" value="BROMODOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bromo" evidence="5">
        <location>
            <begin position="698"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="277"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="552"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="818"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="901"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1050"/>
            <end position="1115"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="647"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="283"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="298"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="403"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="430"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="552"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="825"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="901"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1062"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1089"/>
            <end position="1102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1217" mass="141264" checksum="2BAE9AAF66F3206B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYS7</accession>
    <name>A0A1J1GYS7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00368100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529261.1">
        <property type="nucleotide sequence ID" value="XM_028672738.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732211"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00368100"/>
    <dbReference type="OMA" id="KNEHPKN"/>
    <dbReference type="OrthoDB" id="372678at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1011"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="328"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="499"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1840"/>
            <end position="1890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1025"/>
            <end position="1035"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2385" mass="285235" checksum="DBCF4D1F33C00F5C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYU9</accession>
    <name>A0A1J1GYU9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Importin beta, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00520800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530433.1">
        <property type="nucleotide sequence ID" value="XM_028674040.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYU9"/>
    <dbReference type="GeneID" id="39733741"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00520800"/>
    <dbReference type="OMA" id="PADCFFF"/>
    <dbReference type="OrthoDB" id="10263328at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058584">
        <property type="entry name" value="IMB1_TNPO1-like_TPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040122">
        <property type="entry name" value="Importin_beta"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10527">
        <property type="entry name" value="IMPORTIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13513">
        <property type="entry name" value="HEAT_EZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25574">
        <property type="entry name" value="TPR_IMB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="6">
        <location>
            <begin position="24"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="877" mass="99975" checksum="7FAA2567390BE231" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYV3</accession>
    <name>A0A1J1GYV3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00341300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529000.1">
        <property type="nucleotide sequence ID" value="XM_028672449.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYV3"/>
    <dbReference type="GeneID" id="39731943"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00341300"/>
    <dbReference type="OMA" id="HINRHDQ"/>
    <dbReference type="OrthoDB" id="391249at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="329" mass="39039" checksum="B9223FF72185AC6F" modified="2017-02-15" version="1">MNCYDNISNSDSNSINLKKELHNTLVVIGFIIETILNDNNILESVNINDIYKTLYDIFKSRYMCILSNSNSYKEKDNTDQNKENLLNEEIKLKFTKIFYGQKKKKELITIKNLSCIKYAIAGCIYLHGKISNKNISLRNILNIIDYNISLLNNNIYTKYGISKSYIRDVTSSINHYKPIIKENIYHEKEESLKMERICLYSSRFKLSNNISKYSLLYELMFITRSPFIINKFLFSVFNDVICIPNINDKYNDVVIVISCILFVNHFFYHINQKYKINSQFFCFIKKIYQYQVEKIMNIFLLLNTTNHIQEVKNIISLMKKIIYLYSIKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYZ5</accession>
    <name>A0A1J1GYZ5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Acyl-CoA-binding domain-containing protein 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00526100</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ACBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530486.1">
        <property type="nucleotide sequence ID" value="XM_028674100.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYZ5"/>
    <dbReference type="GeneID" id="39733794"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00526100"/>
    <dbReference type="OMA" id="TPTNECK"/>
    <dbReference type="OrthoDB" id="346910at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000062">
        <property type="term" value="F:fatty-acyl-CoA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.80.10:FF:000022">
        <property type="entry name" value="acyl-CoA-binding domain-containing protein 6 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000582">
        <property type="entry name" value="Acyl-CoA-binding_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035984">
        <property type="entry name" value="Acyl-CoA-binding_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014352">
        <property type="entry name" value="FERM/acyl-CoA-bd_prot_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23310:SF62">
        <property type="entry name" value="ACYL-COA BINDING PROTEIN 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23310">
        <property type="entry name" value="ACYL-COA-BINDING PROTEIN, ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00887">
        <property type="entry name" value="ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00689">
        <property type="entry name" value="ACOABINDINGP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47027">
        <property type="entry name" value="Acyl-CoA binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51228">
        <property type="entry name" value="ACB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ACB" evidence="8">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG97685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="89" mass="10591" checksum="0DC83E0E908C07CC" modified="2017-02-15" version="1">MAEKFEKCVKFINSLPKDENISVEIKLELYKYFKQSTIGNCNISAPSFFKFEEKKKYEAWKSVENLSMEDAKMKYVEIVTSLYPNWDKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ04</accession>
    <name>A0A1J1GZ04_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00022300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000113">
        <property type="protein sequence ID" value="CRG97788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530589.1">
        <property type="nucleotide sequence ID" value="XM_028674214.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ04"/>
    <dbReference type="GeneID" id="39728746"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00022300"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="133" mass="16771" checksum="65BE94DDC722061D" modified="2017-02-15" version="1">MTLLEEFMKDEWQKEKEYFFRTMMEELKIQENLDEHVIILEIKKKRSRNAILDIEKVEIEKWKKKKWFIELMLEMNNKEKTYIKDVYKDMIAKNNEDRIKNPMLEMQKIIWKKHCEDIHKRWIEKNNKEILQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ53</accession>
    <name>A0A1J1GZ53_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">AP-4 complex subunit epsilon, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00416600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529389.1">
        <property type="nucleotide sequence ID" value="XM_028672881.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ53"/>
    <dbReference type="GeneID" id="39732697"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00416600"/>
    <dbReference type="OrthoDB" id="29308at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030124">
        <property type="term" value="C:AP-4 adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050840">
        <property type="entry name" value="Adaptor_Complx_Large_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017109">
        <property type="entry name" value="AP4_complex_esu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22780">
        <property type="entry name" value="ADAPTIN, ALPHA/GAMMA/EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037097">
        <property type="entry name" value="AP4_complex_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="6">
        <location>
            <begin position="44"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="547"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="848"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="900"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="547"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="566"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="858"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="907"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="948"/>
            <end position="959"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1239" mass="144599" checksum="DE8B7EAC581A1CF6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZG5</accession>
    <name>A0A1J1GZG5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PRP5</name>
        <name evidence="10" type="ORF">PGAL8A_00029800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530662.1">
        <property type="nucleotide sequence ID" value="XM_028674294.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728821"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00029800"/>
    <dbReference type="OMA" id="YWKLKTR"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000079">
        <property type="entry name" value="probable ATP-dependent RNA helicase DDX17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="739"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="928"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="463"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="619"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1183"/>
            <end position="1258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="9"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="78"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="187"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="267"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="279"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="463"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="552"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG97863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1434" mass="169222" checksum="5B75A4E0661744AD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZK6</accession>
    <name>A0A1J1GZK6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome b5-like heme/steroid binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00430900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the cytochrome b5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529533.1">
        <property type="nucleotide sequence ID" value="XM_028673040.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZK6"/>
    <dbReference type="GeneID" id="39732841"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00430900"/>
    <dbReference type="OMA" id="FQYHPWV"/>
    <dbReference type="OrthoDB" id="260519at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004128">
        <property type="term" value="F:cytochrome-b5 reductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000007">
        <property type="entry name" value="Sulfite oxidase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051872">
        <property type="entry name" value="Cytochrome_b5/Flavoprotein_Rdt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46237:SF1">
        <property type="entry name" value="CYTOCHROME B5 REDUCTASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46237">
        <property type="entry name" value="CYTOCHROME B5 REDUCTASE 4 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="5">
        <location>
            <begin position="53"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="130" mass="15290" checksum="57074EC144DE276F" modified="2017-02-15" version="1">MPEEDEKKLKPANVEAKTSNKFLNVKPKTPYGTNQLLYISLSENLKDKYNTRDKYITKEEVAKHNKEDDAWIIYKNKVYDITLYLKYHPGGKKILLNQSGKDITEFVLKFHPWVNVEEILKHTLIGYIEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZR4</accession>
    <name>A0A1J1GZR4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00535300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530576.1">
        <property type="nucleotide sequence ID" value="XM_028674200.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZR4"/>
    <dbReference type="GeneID" id="39733886"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00535300"/>
    <dbReference type="OrthoDB" id="392050at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="108" mass="12388" checksum="D23F072B94A82B45" modified="2017-02-15" version="1">MPLNVITPSEPKDPSMIFKYKTKEEYSGELEGILILCFLGIFVGIIFKVIEIIFVIIFVILSVYLTAKNGEINVLSSLPLILMILMTSGITWIQQKAFYKRHEKKFET</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZS7</accession>
    <name>A0A1J1GZS7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00374800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529328.1">
        <property type="nucleotide sequence ID" value="XM_028672813.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZS7"/>
    <dbReference type="GeneID" id="39732278"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00374800"/>
    <dbReference type="OMA" id="KMWRVAM"/>
    <dbReference type="OrthoDB" id="430505at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036257">
        <property type="entry name" value="Cyt_c_oxidase_su2_TM_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81464">
        <property type="entry name" value="Cytochrome c oxidase subunit II-like, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="76" mass="8847" checksum="A92E5CA8ED4793B5" modified="2017-02-15" version="1">MLEKKSEFLSKCFNIFKRNFTPNISLTRCDAPKMWRVAMGGVDPATPQAESFINFHNHTVTYMVFIMFTVLLSLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZT4</accession>
    <name>A0A1J1GZT4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="1">PPIase</shortName>
            <ecNumber evidence="1">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00529800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530522.1">
        <property type="nucleotide sequence ID" value="XM_028674139.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZT4"/>
    <dbReference type="GeneID" id="39733831"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00529800"/>
    <dbReference type="OMA" id="KLGNPMY"/>
    <dbReference type="OrthoDB" id="193499at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016018">
        <property type="term" value="F:cyclosporin A binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11071:SF561">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="2">
        <location>
            <begin position="65"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="276" mass="31915" checksum="09A766B6269FD23C" modified="2017-02-15" version="1">MINKSFRASKIIGKKCFHWWNNLHISWKLAIGFSALFPPLWNYNERRKAKEKQIYYNKAIKDYVFFDIAVENKYIGRILIGLYSDQVPLSAENFIQLAEGYKIKDKYIGYRNTFIHKVYPGICLVGGNVLNDKEGLSIYGKKFPDENFDMEFVQDGDVALYNDGPHNNSSQFIITFSPMPILHKHNVVIGTVLKGMNIIRMIEKLGTKLGNPMYNIKIINCGIYKSLEENGPPFFTITNILDKNNAKYISKKEFENLSLQERQSLMINTKNSTKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZX3</accession>
    <name>A0A1J1GZX3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00046400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530830.1">
        <property type="nucleotide sequence ID" value="XM_028674482.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZX3"/>
    <dbReference type="GeneID" id="39728989"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00046400"/>
    <dbReference type="OMA" id="CPISEML"/>
    <dbReference type="OrthoDB" id="392908at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG98033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="109" mass="13239" checksum="B6DE0911CBB178C5" modified="2017-02-15" version="1">MKREKIKNKINDKIDKIDKNNTNHIIKKKKKRKKKIIINVRRRIKKKEVINNDMKERSTKKNALNKEISKYKGNNMKSINKFVFFEKEYNLNEIENCQISEFLLKAEDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZY8</accession>
    <name>A0A1J1GZY8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">mRNA (guanine-N(7))-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.56</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00045100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a 5'-end (5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-methionine = a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:67008"/>
            <dbReference type="Rhea" id="RHEA-COMP:17166"/>
            <dbReference type="Rhea" id="RHEA-COMP:17167"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:167617"/>
            <dbReference type="EC" id="2.1.1.56"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.56" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530817.1">
        <property type="nucleotide sequence ID" value="XM_028674468.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZY8"/>
    <dbReference type="GeneID" id="39728976"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00045100"/>
    <dbReference type="OMA" id="EEWYYYD"/>
    <dbReference type="OrthoDB" id="10248867at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004482">
        <property type="term" value="F:mRNA 5'-cap (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004971">
        <property type="entry name" value="mRNA_G-N7_MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039753">
        <property type="entry name" value="RG7MT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12189:SF2">
        <property type="entry name" value="MRNA CAP GUANINE-N7 METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12189">
        <property type="entry name" value="MRNA GUANINE-7- METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03291">
        <property type="entry name" value="mRNA_G-N7_MeTrfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51562">
        <property type="entry name" value="RNA_CAP0_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-0506">mRNA capping</keyword>
    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MRNA cap 0 methyltransferase" evidence="9">
        <location>
            <begin position="682"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="251"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="336"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="532"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="251"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="268"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG98020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1029" mass="122411" checksum="AFB4B0200E63BF73" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H072</accession>
    <name>A0A1J1H072_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00058000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530942.1">
        <property type="nucleotide sequence ID" value="XM_028674606.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H072"/>
    <dbReference type="GeneID" id="39729105"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00058000"/>
    <dbReference type="OMA" id="CEMRRDR"/>
    <dbReference type="OrthoDB" id="386561at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="105" mass="12691" checksum="0F85BE0D4D5EA639" modified="2017-02-15" version="1">MYVNLSRNIKRIWNVKNIYMKKENILVNKLLYSANFENSLNTESCAFNDNFCFLNQSFINFSFQKDNKIIYEMRRDRGGTVRKKLSREKKKTQKKQKKDSIDIHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0S7</accession>
    <name>A0A1J1H0S7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Erythrocyte vesicle protein 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">EVP1</name>
        <name evidence="2" type="ORF">PGAL8A_00060600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530968.1">
        <property type="nucleotide sequence ID" value="XM_028674635.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0S7"/>
    <dbReference type="GeneID" id="39729131"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00060600"/>
    <dbReference type="OrthoDB" id="386326at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="660" mass="77173" checksum="78A5A3915571A996" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0W8</accession>
    <name>A0A1J1H0W8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00475700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529981.1">
        <property type="nucleotide sequence ID" value="XM_028673539.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0W8"/>
    <dbReference type="GeneID" id="39733290"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00475700"/>
    <dbReference type="OMA" id="NPNVPQF"/>
    <dbReference type="OrthoDB" id="10496633at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="389" mass="44054" checksum="BF61A18DA973BD01" modified="2017-02-15" version="1">MRFCSIKNDNLLRKVSASDRKNTEHCSFFLSEVQNKISQIKIYKNSMLSRLFTVVLFFLLYNFFQCMSKKQNKVTTVLLCNKYHSRKLAQQGPMFVRGKIKSTNKSQLKEAVKKPLHIQEGDNVLVIEGNKIQIENKTPYMQETGDDKAKFNNENASAPVNENIMKIRLGNFGNNIPDTQNPNVPQFGNIGIQNPNIPQFGNVGIQNPNVPQFGNFGNQNPSIPQSEIFGNQNPNVPQFGNIGIQNPNVPQFGNIGIQNPSVPQFGNLGIQNPNVPQFGNLGIQNPNVPQFGNIGIQNPSIPQFGSMGNSLPMRRQNKKTDKNKRENAMDINMEEVEVMDVTEQGFSDPTMKINWPVFHNNARGNDMNILKLRKQWQQTVYDDWKKNMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1U1</accession>
    <name>A0A1J1H1U1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Protoporphyrinogen oxidase</fullName>
            <ecNumber evidence="4 11">1.3.3.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">PPO</name>
        <name evidence="14" type="ORF">PGAL8A_00487300</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>protoporphyrinogen IX + 3 O2 = protoporphyrin IX + 3 H2O2</text>
            <dbReference type="Rhea" id="RHEA:25576"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:57307"/>
            <dbReference type="EC" id="1.3.3.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="11">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrin-IX from protoporphyrinogen-IX: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Protoporphyrinogen oxidase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.4" evidence="4 11"/>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530096.1">
        <property type="nucleotide sequence ID" value="XM_028673667.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1U1"/>
    <dbReference type="GeneID" id="39733406"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00487300"/>
    <dbReference type="OrthoDB" id="419752at2759"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00324"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004729">
        <property type="term" value="F:oxygen-dependent protoporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004572">
        <property type="entry name" value="Protoporphyrinogen_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050464">
        <property type="entry name" value="Zeta_carotene_desat/Oxidored"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00562">
        <property type="entry name" value="proto_IX_ox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923:SF3">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0274">FAD</keyword>
    <keyword evidence="5 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8 11" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9 11" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="Amine oxidase" evidence="13">
        <location>
            <begin position="409"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU367069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG97294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="607" mass="72493" checksum="8553BADE0BD670A3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H309</accession>
    <name>A0A1J1H309_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00030400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530668.1">
        <property type="nucleotide sequence ID" value="XM_028674301.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H309"/>
    <dbReference type="GeneID" id="39728827"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00030400"/>
    <dbReference type="OMA" id="HKEYKEE"/>
    <dbReference type="OrthoDB" id="387465at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="149" mass="17629" checksum="45E506A9DCF11FC0" modified="2017-02-15" version="1">MSERDGEIHKEYKEENILDDKEKEFRGNQNELNENDTKNKSDRTYIDPKMYNKFKNDGSFLEQVLALQKEKKVRKSKTSENSEPKKKKTKKKDVEEKKEKSLDSNVKDEQDDVEDERETQIKNEYIEKINKMKEQGFFTDKGIGAGLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H352</accession>
    <name>A0A1J1H352_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AP5B1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00534400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530567.1">
        <property type="nucleotide sequence ID" value="XM_028674189.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733877"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00534400"/>
    <dbReference type="OMA" id="HNVYIPY"/>
    <dbReference type="OrthoDB" id="646197at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030119">
        <property type="term" value="C:AP-type membrane coat adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038741">
        <property type="entry name" value="AP5B1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048981">
        <property type="entry name" value="AP5B1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34033">
        <property type="entry name" value="AP-5 COMPLEX SUBUNIT BETA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34033:SF1">
        <property type="entry name" value="AP-5 COMPLEX SUBUNIT BETA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21590">
        <property type="entry name" value="AP5B1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="363"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="587"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1614"/>
            <end position="1636"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1731"/>
            <end position="1751"/>
        </location>
    </feature>
    <feature type="domain" description="AP5B1 C-terminal" evidence="2">
        <location>
            <begin position="2072"/>
            <end position="2112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2127" mass="258748" checksum="66945E1999A1C8F5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H489</accession>
    <name>A0A1J1H489_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">U4/U6 small nuclear ribonucleoprotein PRP31, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">PRPF31</name>
        <name evidence="11" type="ORF">PGAL8A_00059700</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PRP31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530959.1">
        <property type="nucleotide sequence ID" value="XM_028674625.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H489"/>
    <dbReference type="GeneID" id="39729122"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00059700"/>
    <dbReference type="OMA" id="IGNGPMD"/>
    <dbReference type="OrthoDB" id="4771285at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005687">
        <property type="term" value="C:U4 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000244">
        <property type="term" value="P:spliceosomal tri-snRNP complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.4070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.90">
        <property type="entry name" value="Nop domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042239">
        <property type="entry name" value="Nop_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002687">
        <property type="entry name" value="Nop_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036070">
        <property type="entry name" value="Nop_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012976">
        <property type="entry name" value="NOSIC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027105">
        <property type="entry name" value="Prp31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019175">
        <property type="entry name" value="Prp31_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13904">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR PRP31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13904:SF0">
        <property type="entry name" value="U4_U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01798">
        <property type="entry name" value="Nop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09785">
        <property type="entry name" value="Prp31_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00931">
        <property type="entry name" value="NOSIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89124">
        <property type="entry name" value="Nop domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51358">
        <property type="entry name" value="NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Nop" evidence="10">
        <location>
            <begin position="241"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="89"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG98162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="503" mass="57975" checksum="E7D3DBD5CBE27212" modified="2017-02-15" version="1">MATLADSFLKDLEDLELEDDNFSDFNIQKKDNEEEKIEDNDDYEEIVDAIEEFLNERKKKKERKISELLYNEEFLKMMNDIKDYIREEEEQHEQMNDNKALRERREKDDNEKEKDEEEVLIEKCIELIIKIDTEILNIHKYVKDIYSTKFPELDSIVYSPLEYISVVSKIKNEIDLTNIDFSDILPNTTVMAITVASSMTTGIKLSDHLLKNCLSFCSEALELNENRKMILLYLESKMFLLAPNLTMLLGSALTARLISSVGSLKNLSVTSSQNIIVVGGSKKSVLGLSNVNKTFGIGILSSSEIVQSVPDSYKKKAIKLLAGKCSLAARIDYFKKYREGQYGLLLRENVISHLIKLQEPLPMKQKKILPMPDEKRRRRRGGRRYRKLKEKTQITELRKQINRLPFGPNTTDDFYIFSDQNTTLLNSNITKLKYQTKQKSNISKKKNMNIQSSGVTGGLSSSLIFTPLQGIELYNPSVNQKNDQNENKYFSSTAQFRKVQSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKW3</accession>
    <name>A0A1J1GKW3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00072600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525844.1">
        <property type="nucleotide sequence ID" value="XM_028674867.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKW3"/>
    <dbReference type="GeneID" id="39729251"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00072600"/>
    <dbReference type="OrthoDB" id="392810at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="393" mass="46085" checksum="1A377B7EB660237F" modified="2017-02-15" version="1">MALINFKEKIQILLKLKESLIPQVDGNFIKNWEMEAIKYQSTSENILVELKNINFIEGLVSAISSQLSYLRINLQNYQNMSEQEKDKFKRLYVLAALGLIAKLKLILFFSTYINSREHKKFKNFPNINENNYELQQNNCGNSYDNEIDLSINNSEDYMNGKSTKKNSLLNNLNDYYSQFHNFTDNYKENIFNAMILNNIVNYNSQDNSGKNLNNSNFNEKSFNVYNNNNNNNNNYNSHFTNNLEDLSLAMMNNFSLQKNDNLQNSSILTSKKRSLPSPQNQNKTVSFLKNSQTLNNIENNQEEHMLNYNNQINNESQKFFHQNQEQISKYLTNINQNIHSTNNENSELDNCNSNLNSYYQFHNDNGQSKNVLRSYNNKVYGINDNIYKNSYYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL28</accession>
    <name>A0A1J1GL28_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00077500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525895.1">
        <property type="nucleotide sequence ID" value="XM_028670188.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL28"/>
    <dbReference type="GeneID" id="39729300"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00077500"/>
    <dbReference type="OrthoDB" id="373490at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="79" mass="9553" checksum="2A5DEDC8EF04D7CC" modified="2017-02-15" version="1">MTQYMNVSENYKVIKDVEDTDDRTYMDKSLYELYDNENVKYPFFIAPRYDYYFTSEGYTTIYNTPIIKKSKTKKLFGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL59</accession>
    <name>A0A1J1GL59_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sugar transporter, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00076500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525881.1">
        <property type="nucleotide sequence ID" value="XM_028670033.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL59"/>
    <dbReference type="GeneID" id="39729290"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00076500"/>
    <dbReference type="OMA" id="VYYIPWT"/>
    <dbReference type="OrthoDB" id="197206at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039672">
        <property type="entry name" value="MFS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11328:SF24">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11328">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13347">
        <property type="entry name" value="MFS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="109"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="223"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="259"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="319"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="350"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="384"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="411"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="453"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="496"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="563" mass="64206" checksum="140E8DD8B0FDD9D0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLF5</accession>
    <name>A0A1J1GLF5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transcription factor with AP2 domain(S)</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00094400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526060.1">
        <property type="nucleotide sequence ID" value="XM_028672021.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729468"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00094400"/>
    <dbReference type="OMA" id="RKYILCY"/>
    <dbReference type="OrthoDB" id="386386at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="497"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1178"/>
            <end position="1203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1374"/>
            <end position="1398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1975"/>
            <end position="1999"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2147"/>
            <end position="2199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2531"/>
            <end position="2600"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1113"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2406"/>
            <end position="2433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="497"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="507"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="520"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="627"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="673"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="686"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1178"/>
            <end position="1196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1374"/>
            <end position="1391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1975"/>
            <end position="1997"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="2165"/>
            <end position="2175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2176"/>
            <end position="2199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2548"/>
            <end position="2562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2563"/>
            <end position="2581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2588"/>
            <end position="2600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2757" mass="325904" checksum="A0BDEC53AAE03A0C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLJ6</accession>
    <name>A0A1J1GLJ6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">AP complex subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00094700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526063.1">
        <property type="nucleotide sequence ID" value="XM_028672054.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLJ6"/>
    <dbReference type="GeneID" id="39729471"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00094700"/>
    <dbReference type="OMA" id="ANCMHAL"/>
    <dbReference type="OrthoDB" id="10254310at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030131">
        <property type="term" value="C:clathrin adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030276">
        <property type="term" value="F:clathrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="entry name" value="TATA-Binding Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026739">
        <property type="entry name" value="AP_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016342">
        <property type="entry name" value="AP_complex_bsu_1_2_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015151">
        <property type="entry name" value="B-adaptin_app_sub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11134">
        <property type="entry name" value="ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09066">
        <property type="entry name" value="B2-adapt-app_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002291">
        <property type="entry name" value="AP_complex_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01020">
        <property type="entry name" value="B2-adapt-app_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Beta-adaptin appendage C-terminal subdomain" evidence="7">
        <location>
            <begin position="738"/>
            <end position="851"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="854" mass="99939" checksum="59F317F2D8B18D8C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLR1</accession>
    <name>A0A1J1GLR1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00107300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526190.1">
        <property type="nucleotide sequence ID" value="XM_028673466.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLR1"/>
    <dbReference type="GeneID" id="39729599"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00107300"/>
    <dbReference type="OrthoDB" id="371183at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="235" mass="28644" checksum="B5038D86BD5C294E" modified="2017-02-15" version="1">MDGKIRLASIHELKEIFIKEYTEYIKLLKNIELYYQKLQLNWFKFHLFYEPNKNDDFAYYKEVKDKKKNGKKSRSYCSYKAIEEDLKVIKQKEKQNNCYYFKTFRKSFILYTLRDITNSVELYLNIKIESMNKLKKNVLTDINNFCREEIKKIIFLIILCELKLNNLLISQRKTDDNNKLNTKIIKNIIECCKKVIHEITKNLIPHFLLFNIFSSPNYFNYQFNYFDNFIESIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLU2</accession>
    <name>A0A1J1GLU2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">V-type proton ATPase subunit C</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00102200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the V-ATPase C subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526138.1">
        <property type="nucleotide sequence ID" value="XM_028672888.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLU2"/>
    <dbReference type="GeneID" id="39729547"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00102200"/>
    <dbReference type="OMA" id="SEGFIAW"/>
    <dbReference type="OrthoDB" id="6605928at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000221">
        <property type="term" value="C:vacuolar proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14785">
        <property type="entry name" value="V-ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1460.10">
        <property type="entry name" value="subunit c (vma5p) of the yeast v-atpase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1180">
        <property type="entry name" value="Vacuolar atp synthase subunit c, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004907">
        <property type="entry name" value="ATPase_V1-cplx_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036132">
        <property type="entry name" value="Vac_ATP_synth_c_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10137">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10137:SF0">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03223">
        <property type="entry name" value="V-ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118203">
        <property type="entry name" value="Vacuolar ATP synthase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="383" mass="45100" checksum="B927A8667DB2DB05" modified="2017-02-15" version="1">MSEIPMCLFIACSTRDNTSREYIYTILKNRLLGSHICIDTNILDVPTNLKFCSFDDLLKCADDLQKYDSYAYGCLKKIEKIAKEYDENIELKIIYQRQHINIDQYIRRFSWDDAKYPRNRSLTDTVDIMINNITKLSDEIQIKSSMLNDLKEKKKKDIPISDSNNFLLRNLNEILTPQTVSESDFIETEHLTTLVACIPKNLVEEWKNTYEKFCEYVVPRSTEQFKDLVDKDGNTLWKVLVFKKYAENFKQAAKLKKIVVKSFKYDEKQYNDMMETRTKIEAEIIRQETFLRRMCLAAFSDIFIAFIHINILRVFCESVLRFGVPPNFASFSIRINGESKEKKVRKKLYDIFSSTDSIGKNYIKKSDENDEEIYPYVSVSFKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLW4</accession>
    <name>A0A1J1GLW4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ELM2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00104600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526162.1">
        <property type="nucleotide sequence ID" value="XM_028673154.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLW4"/>
    <dbReference type="GeneID" id="39729571"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00104600"/>
    <dbReference type="OMA" id="NIGEKHQ"/>
    <dbReference type="OrthoDB" id="378925at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000949">
        <property type="entry name" value="ELM2_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51156">
        <property type="entry name" value="ELM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELM2" evidence="3">
        <location>
            <begin position="12"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="36"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="81"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="112"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="130"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="198" mass="23495" checksum="01DE73F05658BA18" modified="2017-02-15" version="1">MAKRKYMSKVDGKINVGEKYQAKIPNLIIRDYDNNLNVNNTTDKEVKYSKETTKKKKAKTEKNDECLYNSNNENTNKIEEEISEVETNEAESNENEYETNENETNENKMDVNNLDNYENENNTNEKVSDENEEENEEENEEENEEENEEENEEENEEENEEESEEENEEENEDENEEENEEENEEESEEDGINLNGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM19</accession>
    <name>A0A1J1GM19_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mitochondrial distribution and morphology protein 35</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00107600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRIAP1/MDM35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526193.1">
        <property type="nucleotide sequence ID" value="XM_028673499.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM19"/>
    <dbReference type="GeneID" id="39729602"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00107600"/>
    <dbReference type="OMA" id="YQICIIN"/>
    <dbReference type="OrthoDB" id="19091at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990050">
        <property type="term" value="F:phosphatidic acid transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007918">
        <property type="entry name" value="MDM35_apoptosis"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46403">
        <property type="entry name" value="TP53-REGULATED INHIBITOR OF APOPTOSIS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46403:SF1">
        <property type="entry name" value="TP53-REGULATED INHIBITOR OF APOPTOSIS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05254">
        <property type="entry name" value="UPF0203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="81" mass="9648" checksum="4CF91E3F221A466E" modified="2017-02-15" version="1">MGNVKKEFSKDTLKAHLEAIEECKEKKEKYVKCFNNWYKNNFLKGDLTQACDDYYEDYQICVLNDLNKKGLSHLTNFENEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM80</accession>
    <name>A0A1J1GM80_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTP cyclohydrolase 1</fullName>
            <ecNumber evidence="4">3.5.4.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">GTP cyclohydrolase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00125100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>GTP + H2O = 7,8-dihydroneopterin 3'-triphosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17473"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="EC" id="3.5.4.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GTP cyclohydrolase I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.16" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526366.1">
        <property type="nucleotide sequence ID" value="XM_028674768.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM80"/>
    <dbReference type="GeneID" id="39729776"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00125100"/>
    <dbReference type="OMA" id="RGVKEHN"/>
    <dbReference type="OrthoDB" id="10268090at2759"/>
    <dbReference type="UniPathway" id="UPA00848">
        <property type="reaction ID" value="UER00151"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003934">
        <property type="term" value="F:GTP cyclohydrolase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1130.10:FF:000001">
        <property type="entry name" value="GTP cyclohydrolase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001474">
        <property type="entry name" value="GTP_CycHdrlase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020602">
        <property type="entry name" value="GTP_CycHdrlase_I_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109:SF7">
        <property type="entry name" value="GTP CYCLOHYDROLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109">
        <property type="entry name" value="GTP CYCLOHYDROLASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01227">
        <property type="entry name" value="GTP_cyclohydroI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55620">
        <property type="entry name" value="Tetrahydrobiopterin biosynthesis enzymes-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GTP cyclohydrolase I" evidence="9">
        <location>
            <begin position="199"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="140"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="140"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="153"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG93544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="397" mass="46415" checksum="05EC527F20DF5116" modified="2017-02-15" version="1">MMKNLHLNRSNEIYSESSNENEKSNSNYLLNTKKVKKKSKREFEKNSHNLNDTIMNNGLKKCEKKAFNVIEKGKKRFKRLAVKKKCNSNVKLQDNANFISNKICILNNENKNGHITSNNNLNDVKIIKNKYCSKKTKIDKMENDTSSKKNEINVKNNDNNNKVSDKNYEKNTLKKIKNKKISDNHTNSSKIENQVFDISHHIYNILNILNLPKSDILKRTNKRFAETFLYLTNGYNVDIEKIFKGSMYKRKYKNNSVIKITGIQINSLCKHHLLPFQGICTIEYVPNKYIMGLSKFSRIVDAFSRRLQLQEDLTNDICNILRKYLKPLNLQVTIVAKHLCINMRGVKEHNSTTVTQVCCKLKNNKYTSKSYINNCFKKENDISNYDSINKMNYDENY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMD1</accession>
    <name>A0A1J1GMD1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Zinc finger protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00111100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526227.1">
        <property type="nucleotide sequence ID" value="XM_028673877.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMD1"/>
    <dbReference type="GeneID" id="39729636"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00111100"/>
    <dbReference type="OrthoDB" id="20534at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045234">
        <property type="entry name" value="Unkempt-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14493:SF50">
        <property type="entry name" value="RING FINGER PROTEIN UNKEMPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14493">
        <property type="entry name" value="UNKEMPT FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="5">
        <location>
            <begin position="14"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="14"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="512" mass="60086" checksum="A8E77256FDBB0CDC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMQ3</accession>
    <name>A0A1J1GMQ3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Iron transporter, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00124800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CCC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526363.1">
        <property type="nucleotide sequence ID" value="XM_028674764.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMQ3"/>
    <dbReference type="GeneID" id="39729773"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00124800"/>
    <dbReference type="OMA" id="QMCCVGG"/>
    <dbReference type="OrthoDB" id="73465at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030026">
        <property type="term" value="P:intracellular manganese ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02434">
        <property type="entry name" value="Nodulin-21_like_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008217">
        <property type="entry name" value="Ccc1_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31851">
        <property type="entry name" value="FE(2+)/MN(2+) TRANSPORTER PCL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01988">
        <property type="entry name" value="VIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="274" mass="31221" checksum="45CF49A24F57016F" modified="2017-02-15" version="1">MVSKKTLEAQKAFYNEDVEKSKEAHDFYHNLDKHGEDHNLDRDNLKTIIFGSLDGIITMFAIVSGCVGAKITPTQVIIIGIGNLFANAISMGFSEYTSSSAQRDFMLAEKKREEWEIENCPSEEKQEMIDIYMNKYKFDSEDARNLVEIAFRNKNFFLEHMMSEELGLIITNEDKNESMKKGIIMFLSFCVFGLIPLSSFVAYIVFFEYTDYNTSFLVVFISTLITLFILGLFKSQFTNQKPLKCAFCMLLNGIIAGIVPFLLGILLKNNIADV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMV8</accession>
    <name>A0A1J1GMV8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit L</fullName>
            <shortName evidence="4">eIF3l</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00140600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eIF-3 subunit L family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526522.1">
        <property type="nucleotide sequence ID" value="XM_028674941.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMV8"/>
    <dbReference type="GeneID" id="39729930"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00140600"/>
    <dbReference type="OMA" id="AGWFIRN"/>
    <dbReference type="OrthoDB" id="15082at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03011">
        <property type="entry name" value="eIF3l"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019382">
        <property type="entry name" value="eIF3l"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13242">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13242:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10255">
        <property type="entry name" value="Paf67"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="230"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="267"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="570" mass="67864" checksum="9B983AE85C6994DF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN39</accession>
    <name>A0A1J1GN39_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TRAP-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00145300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526569.1">
        <property type="nucleotide sequence ID" value="XM_028674993.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN39"/>
    <dbReference type="GeneID" id="39729977"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00145300"/>
    <dbReference type="OMA" id="ETNIPCC"/>
    <dbReference type="OrthoDB" id="372508at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd01450">
        <property type="entry name" value="vWFA_subfamily_ECM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.100.10">
        <property type="entry name" value="Thrombospondin type-1 (TSP1) repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000884">
        <property type="entry name" value="TSP1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036383">
        <property type="entry name" value="TSP1_rpt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00209">
        <property type="entry name" value="TSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50092">
        <property type="entry name" value="TSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012046039" evidence="5">
        <location>
            <begin position="20"/>
            <end position="1212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1151"/>
            <end position="1172"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="6">
        <location>
            <begin position="33"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="6">
        <location>
            <begin position="300"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="497"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="777"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="979"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1067"/>
            <end position="1121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1189"/>
            <end position="1212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="777"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="981"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="993"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1075"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1112"/>
            <end position="1121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1201"/>
            <end position="1212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1212" mass="141751" checksum="D60C4BE3F254B7AA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN46</accession>
    <name>A0A1J1GN46_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00150500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526618.1">
        <property type="nucleotide sequence ID" value="XM_028675048.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN46"/>
    <dbReference type="GeneID" id="39730029"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00150500"/>
    <dbReference type="OMA" id="FYLYIYT"/>
    <dbReference type="OrthoDB" id="372103at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="5"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="209" mass="25577" checksum="BA504A55E39E8E46" modified="2017-02-15" version="1">MFLFFYLNISHLFIASLCYQMIYIDSFEDNYDNELENISCSWRYFCDENFNFCEYGCSSKKKLKKGYNLLNTSSLHDKCFVNLECDNYDIFFDSENLIYFIYFSKIFFLINPDFTLYVNLMKRSNIKGNIGRVTLNENNLNEKNRQDKNKKILNIFQKINFYRNLVTKKFKKKLIKLLIFFILIHMIFFYLYIYTYLNLKKYDKKKQNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNB7</accession>
    <name>A0A1J1GNB7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">ER membrane protein complex subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">EMC3</name>
        <name evidence="9" type="ORF">PGAL8A_00166700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the EMC3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526780.1">
        <property type="nucleotide sequence ID" value="XM_028669983.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNB7"/>
    <dbReference type="GeneID" id="39730193"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00166700"/>
    <dbReference type="OMA" id="KDMDPRW"/>
    <dbReference type="OrthoDB" id="6745403at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072546">
        <property type="term" value="C:EMC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008568">
        <property type="entry name" value="EMC3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002809">
        <property type="entry name" value="EMC3/TMCO1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13116">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13116:SF5">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01956">
        <property type="entry name" value="EMC3_TMCO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010045">
        <property type="entry name" value="DUF850_TM_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01415">
        <property type="entry name" value="DUF106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR010045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="257" mass="30025" checksum="3BFD40EF33AE1A1E" modified="2017-02-15" version="1">MEPLILDEKIRIYALLPIFIIVVLVCIIKSNMGQMLFPEAKTDVEKLRQNNFLTRFNLLKSNSGFISPVAFLSRKKFYNKPQVGFFNDLPEQINPFDAMLKQDPSDLFGMMKNQIPFFILQLGLGFLINLFFSGYLVAKIPFPLTYKFKSTLQMGMDIDLLDMKFVSSLSWYFLVMFGSSGLISIIDYFVLQEKDRSQNSTFENLMAVQNPLARQPLNMNSVPDLKKFYEQKKEELDNMKYEFLLEDIEYKLIKSWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNP8</accession>
    <name>A0A1J1GNP8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Serine/threonine-protein phosphatase T</fullName>
            <ecNumber evidence="5">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">PGAL8A_00161900</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:20630"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:47005"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526731.1">
        <property type="nucleotide sequence ID" value="XM_028675173.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNP8"/>
    <dbReference type="GeneID" id="39730144"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00161900"/>
    <dbReference type="OMA" id="IHKKYAF"/>
    <dbReference type="OrthoDB" id="445564at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000036">
        <property type="entry name" value="Serine/threonine protein phosphatase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013235">
        <property type="entry name" value="PPP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051134">
        <property type="entry name" value="PPP_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45668">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45668:SF5">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08321">
        <property type="entry name" value="PPP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0464">Manganese</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="9 16" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="16">
        <location>
            <begin position="277"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="18">
        <location>
            <begin position="383"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="93"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="114"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00073946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="CRG93910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="676" mass="78456" checksum="F66EAB3BE494A24D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNZ8</accession>
    <name>A0A1J1GNZ8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00389000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527007.1">
        <property type="nucleotide sequence ID" value="XM_028670235.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNZ8"/>
    <dbReference type="GeneID" id="39732420"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00389000"/>
    <dbReference type="OrthoDB" id="372052at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="396"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="435"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="700" mass="83885" checksum="3068DB797DF73E9E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP72</accession>
    <name>A0A1J1GP72_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Proteasome subunit alpha type-3, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00399300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527110.1">
        <property type="nucleotide sequence ID" value="XM_028670349.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP72"/>
    <dbReference type="GeneID" id="39732523"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00399300"/>
    <dbReference type="OMA" id="RVSMYMH"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000007">
        <property type="entry name" value="Proteasome subunit alpha type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 8" id="KW-0647">Proteasome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="7">
        <location>
            <begin position="8"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="253" mass="29123" checksum="4B086AF828642064" modified="2017-02-15" version="1">MAGLSAGYDLSVSTFSPDGRLYQVEYIYKSINNNNTALSLECKDGIISCCINSNLDKNKMIKKNSYNRLYHINNNIIITYAGLDGDARNIIDRAKSEANNYYYNFHTNIPLHILANRISLYIHAYTLYWHLRPFALSIILASFDKNEKGEIYCIEPNGACYKYSGVVIGKNKEMFKTEIEKKNYKNINVKDALVDIYKIILTSDDHINKDNLSNLVNLSWICEESSYEFQNIEESILENAMKIALEYVEQLNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPD7</accession>
    <name>A0A1J1GPD7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Trafficking protein particle complex subunit 2-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">TRAPPC2L</name>
        <name evidence="1" type="ORF">PGAL8A_00085500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525973.1">
        <property type="nucleotide sequence ID" value="XM_028671054.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPD7"/>
    <dbReference type="GeneID" id="39729379"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00085500"/>
    <dbReference type="OMA" id="FYSDAVC"/>
    <dbReference type="OrthoDB" id="10258445at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006722">
        <property type="entry name" value="Sedlin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04628">
        <property type="entry name" value="Sedlin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="143" mass="16842" checksum="EC1A32E9DEB2457A" modified="2017-02-15" version="1">MSIKSICYLGENDEVLFFYSTEENEEITSRFSIYSTLNNIKKLIDNNEKKGNEKKYDPYLGYVGINLSLFSSYKNYAYVIKVINFKIILTVDDNKNKYTDDILKDVFRRLHKIYADAVCNPFYTEHLETPSFLKKIKKLIETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPF0</accession>
    <name>A0A1J1GPF0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ras-related protein Rab-5A, putative</fullName>
            <ecNumber evidence="2">3.6.5.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">RAB5a</name>
        <name evidence="2" type="ORF">PGAL8A_00401800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.2" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527135.1">
        <property type="nucleotide sequence ID" value="XM_028670376.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPF0"/>
    <dbReference type="GeneID" id="39732548"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00401800"/>
    <dbReference type="OMA" id="GASFFRY"/>
    <dbReference type="OrthoDB" id="63533at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003925">
        <property type="term" value="F:G protein activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01860">
        <property type="entry name" value="Rab5_related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001447">
        <property type="entry name" value="Ras-related protein Rab-1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47978">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08477">
        <property type="entry name" value="Roc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="226" mass="25647" checksum="C25D3DC040742D18" modified="2017-02-15" version="1">MEKKNSYKTVLLGESSVGKSSIVLRLTKDTFHDNTNTTIGASFCTYVVNLNELKVNNSNININNNTINENNDNNNNNNESICNIKFDIWDTAGQERYASIVPLYYRGATCAIVVFDISNSNSLDRAKTWVNQLKISSNYIIILVANKIDKNKFQVDMLEVQKYAQENNLLFIQTSAKTGTNIKNIFYMLAEEIYKNIINKKGSIDSTINKNLINLDKEKNQKKSCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPY3</accession>
    <name>A0A1J1GPY3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00405400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527171.1">
        <property type="nucleotide sequence ID" value="XM_028670416.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPY3"/>
    <dbReference type="GeneID" id="39732584"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00405400"/>
    <dbReference type="OMA" id="QEIFIAN"/>
    <dbReference type="OrthoDB" id="369180at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="92"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="301" mass="35792" checksum="D13159BF1A1F0C46" modified="2017-02-15" version="1">MIDSFQINDLNKFRFSLSEEKIIENFTGNKNNEFLNDSSIPHILKETKNNIPNNLNDEYISFQDNLKDKYNDHGENDNRIKNYSIEILLHKIRNLENEKQYLLKFLEDKKNKELEYLKALETQAALVNSENKKSEYYENEWLNMKSLEYSLVNSGKASLRQTLELFYEEPNLYEKLGSLTKIQEIFITNLIEDHKNLIKERSTISKKYHEAVDANFQLYQQNEMLKAQNMNILEKNKDIIDEETENKLKALNSSLIYVQKENIELKEILDQYTKLITNIKKCSEISDIMKELDKFKNYLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ45</accession>
    <name>A0A1J1GQ45_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Protein kinase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00181200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527241.1">
        <property type="nucleotide sequence ID" value="XM_028670494.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730339"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00181200"/>
    <dbReference type="OrthoDB" id="1714095at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051348">
        <property type="entry name" value="U-box_ubiquitin_ligases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45647">
        <property type="entry name" value="OS02G0152300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45647:SF139">
        <property type="entry name" value="OS02G0152300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="882"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="475"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1202"/>
            <end position="1239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="490"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="502"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="521"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="536"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="910"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2115" mass="255019" checksum="9C263A0A0577CA02" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ97</accession>
    <name>A0A1J1GQ97_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">protein acetyllysine N-acetyltransferase</fullName>
            <ecNumber evidence="1">2.3.1.286</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00210600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the sirtuin family. Class IV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.286" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527524.1">
        <property type="nucleotide sequence ID" value="XM_028670808.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ97"/>
    <dbReference type="GeneID" id="39730633"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00210600"/>
    <dbReference type="OMA" id="FCGRRYL"/>
    <dbReference type="OrthoDB" id="424302at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017136">
        <property type="term" value="F:histone deacetylase activity, NAD-dependent"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050134">
        <property type="entry name" value="NAD-dep_sirtuin_deacylases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11085:SF12">
        <property type="entry name" value="NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="8">
        <location>
            <begin position="25"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="305"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="338"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="341"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1161" mass="137112" checksum="0FDE9AC85A1F75AB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQC0</accession>
    <name>A0A1J1GQC0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">glucose-6-phosphate dehydrogenase (NADP(+))</fullName>
            <ecNumber evidence="2">1.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00213000</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.49" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527548.1">
        <property type="nucleotide sequence ID" value="XM_028670835.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQC0"/>
    <dbReference type="GeneID" id="39730657"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00213000"/>
    <dbReference type="OMA" id="MYNNEFV"/>
    <dbReference type="OrthoDB" id="60984at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004345">
        <property type="term" value="F:glucose-6-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009051">
        <property type="term" value="P:pentose-phosphate shunt, oxidative branch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00966">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001282">
        <property type="entry name" value="G6P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022675">
        <property type="entry name" value="G6P_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022674">
        <property type="entry name" value="G6P_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006148">
        <property type="entry name" value="Glc/Gal-6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429:SF0">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02781">
        <property type="entry name" value="G6PD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00479">
        <property type="entry name" value="G6PD_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01182">
        <property type="entry name" value="Glucosamine_iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00079">
        <property type="entry name" value="G6PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucosamine/galactosamine-6-phosphate isomerase" evidence="9">
        <location>
            <begin position="38"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-6-phosphate dehydrogenase NAD-binding" evidence="8">
        <location>
            <begin position="317"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-6-phosphate dehydrogenase NAD-binding" evidence="8">
        <location>
            <begin position="477"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-6-phosphate dehydrogenase C-terminal" evidence="10">
        <location>
            <begin position="560"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="663"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="672"/>
            <end position="684"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG94733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="883" mass="104010" checksum="BAB5F7811C18F560" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQJ5</accession>
    <name>A0A1J1GQJ5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Splicing factor 3B subunit 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SF3B2</name>
        <name evidence="3" type="ORF">PGAL8A_00221000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527628.1">
        <property type="nucleotide sequence ID" value="XM_028670924.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQJ5"/>
    <dbReference type="GeneID" id="39730737"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00221000"/>
    <dbReference type="OrthoDB" id="10260794at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007180">
        <property type="entry name" value="DUF382"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006568">
        <property type="entry name" value="PSP_pro-rich"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052584">
        <property type="entry name" value="U2_snRNP_Complex_Component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12785">
        <property type="entry name" value="SPLICING FACTOR 3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12785:SF6">
        <property type="entry name" value="SPLICING FACTOR 3B SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04037">
        <property type="entry name" value="DUF382"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04046">
        <property type="entry name" value="PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00581">
        <property type="entry name" value="PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PSP proline-rich" evidence="2">
        <location>
            <begin position="281"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="390"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="600"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="390"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="408"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="610"/>
            <end position="621"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="621" mass="73000" checksum="D589013A70CB140F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQU2</accession>
    <name>A0A1J1GQU2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ENTH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00218900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
            <location evidence="2">trans-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527607.1">
        <property type="nucleotide sequence ID" value="XM_028670901.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQU2"/>
    <dbReference type="GeneID" id="39730716"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00218900"/>
    <dbReference type="OMA" id="CQNCNIV"/>
    <dbReference type="OrthoDB" id="118154at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032588">
        <property type="term" value="C:trans-Golgi network membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03572">
        <property type="entry name" value="ENTH_like_Tepsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013809">
        <property type="entry name" value="ENTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035802">
        <property type="entry name" value="ENTH/VHS_tepsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039273">
        <property type="entry name" value="TEPSIN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21514">
        <property type="entry name" value="AP-4 COMPLEX ACCESSORY SUBUNIT TEPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21514:SF0">
        <property type="entry name" value="AP-4 COMPLEX ACCESSORY SUBUNIT TEPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50942">
        <property type="entry name" value="ENTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENTH" evidence="7">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="450"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="369"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="451"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="936" mass="108774" checksum="D26156F7E178B873" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQW7</accession>
    <name>A0A1J1GQW7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00114000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526256.1">
        <property type="nucleotide sequence ID" value="XM_028674199.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQW7"/>
    <dbReference type="GeneID" id="39729665"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00114000"/>
    <dbReference type="OMA" id="YIGECII"/>
    <dbReference type="OrthoDB" id="10388046at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="288"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="505" mass="60491" checksum="8012E179391B0793" modified="2017-02-15" version="1">MNIFTKKILLIIHGNIKKDIKKYVLTEYGICLIEEITSFVKRNFDDYVIYSSSELINILTSKYIFEKTNILTKVEKRLDNNKSVFNDKELSINFLNSAAFIDNNSKTLKIVKENEYIIETFLRVKKIFKKILLQEKEKNIIFIVCSYIGECIINCLNEYKKYNFKDDLYIYSIKYQTEKINKKDYRVTILDSELLKSRNILKRTYFKLKKKKKIIRKINLFDCCYYQYVDSDYDDNYIINQIESSCSENNELSDQTDDNKSHNFEHLIERKFSQDNFTSFKNDENDSNDSNDSNNSNNSNVIISITDNERKEEEYQQDLLKRHKENKYDNETNTIEEIKIRKEDISNIKDNNDLDNKNESESLFLKIKNFKLGNENDENLCINEILFFLYLKGYSLTEEEISYISTKKEINKNNCMHELNKLEEYFKEKKKNYEEEFYSFFKYANKDNLPISKNILEFILFNYGNKLEKKECEEFFKIADINEKVDCKILLDKLSRIDDSNITYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQX3</accession>
    <name>A0A1J1GQX3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transcription factor with AP2 domain(S), putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ApiAP2</name>
        <name evidence="9" type="ORF">PGAL8A_00208700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527505.1">
        <property type="nucleotide sequence ID" value="XM_028670787.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQX3"/>
    <dbReference type="GeneID" id="39730614"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00208700"/>
    <dbReference type="OrthoDB" id="378734at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028078">
        <property type="entry name" value="ACDC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14733">
        <property type="entry name" value="ACDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00847">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="7">
        <location>
            <begin position="43"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="AP2-coincident C-terminal" evidence="8">
        <location>
            <begin position="483"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="176"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="190"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="213"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="372"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF14733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="571" mass="67791" checksum="88A0F13F2783FBD1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRG3</accession>
    <name>A0A1J1GRG3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">20 kDa chaperonin, chloroplastic</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Chaperonin 10</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Protein Cpn21</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">CPN20</name>
        <name evidence="8" type="ORF">PGAL8A_00245200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the GroES chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527866.1">
        <property type="nucleotide sequence ID" value="XM_028671189.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRG3"/>
    <dbReference type="GeneID" id="39730980"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00245200"/>
    <dbReference type="OMA" id="DIRVNDY"/>
    <dbReference type="OrthoDB" id="184876at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00320">
        <property type="entry name" value="cpn10"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.33.40:FF:000001">
        <property type="entry name" value="10 kDa chaperonin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.33.40">
        <property type="entry name" value="GroES chaperonin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020818">
        <property type="entry name" value="Chaperonin_GroES"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037124">
        <property type="entry name" value="Chaperonin_GroES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018369">
        <property type="entry name" value="Chaprnonin_Cpn10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772">
        <property type="entry name" value="10 KDA HEAT SHOCK PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772:SF63">
        <property type="entry name" value="20 KDA CHAPERONIN, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00166">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00297">
        <property type="entry name" value="CHAPERONIN10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00883">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00681">
        <property type="entry name" value="CHAPERONINS_CPN10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012972615" description="20 kDa chaperonin, chloroplastic" evidence="7">
        <location>
            <begin position="20"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00031971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00073031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00079398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="258" mass="29322" checksum="ABF34AE49ACC2EC5" modified="2017-02-15" version="1">MRLSALMYFAIIFLSSVLTKKINLSNNLNFVNTNPKQFKRTSKSLRATEYKIDNKIIRGPLTPLNEFILIEKNEAFDTTDSGVFIGNTLKDNQYVGKVLSIGTGAINTKNGQRIPIDVEVGDTVIFNPSDGNKIKYNDKECLLISNEEILGKIKDSTEINPFNIIPLYDRVLIKLINVNVNSDSLIFLPESKNSEKSNDGLVISVGNGIYDENNQKIPIDIQRNDYIRFSPFSNESCEFTYKNEKYTFVKARYIMAKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRH2</accession>
    <name>A0A1J1GRH2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Voldacs domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00246000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527874.1">
        <property type="nucleotide sequence ID" value="XM_028671197.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRH2"/>
    <dbReference type="GeneID" id="39730988"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00246000"/>
    <dbReference type="OMA" id="KLYIMEK"/>
    <dbReference type="OrthoDB" id="19714at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034715">
        <property type="term" value="C:pICln-Sm protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039924">
        <property type="entry name" value="ICln/Lot5/Saf5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21399">
        <property type="entry name" value="CHLORIDE CONDUCTANCE REGULATORY PROTEIN ICLN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21399:SF0">
        <property type="entry name" value="METHYLOSOME SUBUNIT PICLN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03517">
        <property type="entry name" value="Voldacs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="202"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="202"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="231" mass="27166" checksum="2B8A3C13AD9D25FB" modified="2017-02-15" version="1">MPISLNSINQEDLNELEKGETILYKGSQIEFIYNKLNLGEGKLYILEKRLIWINENESKKKKVTNFKELATNNIYMNHYEKNKEFYLHLLNDVNNITIDSSNIALHAISSDKKICDRSCVYIQLNTDMSDYFESEKVKDDEDIENTVRVNNINDNEENDSDEDIPYDEIITPEILIICKNETENDAIFRHLSNMDNCLNDDNDIDDDDEYNYEDNYSLNEDEENKGDEKEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRJ5</accession>
    <name>A0A1J1GRJ5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00231200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527729.1">
        <property type="nucleotide sequence ID" value="XM_028671036.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRJ5"/>
    <dbReference type="GeneID" id="39730839"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00231200"/>
    <dbReference type="OrthoDB" id="380135at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="171"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="222"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1010" mass="118960" checksum="E77AB4B47E47B922" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRM9</accession>
    <name>A0A1J1GRM9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">5'-AMP-activated protein kinase subunit beta-1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00165250</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'-AMP-activated protein kinase beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526765.1">
        <property type="nucleotide sequence ID" value="XM_028675210.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRM9"/>
    <dbReference type="GeneID" id="39730178"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00165250"/>
    <dbReference type="OMA" id="CENGIPT"/>
    <dbReference type="OrthoDB" id="531008at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031588">
        <property type="term" value="C:nucleotide-activated protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02859">
        <property type="entry name" value="E_set_AMPKbeta_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032640">
        <property type="entry name" value="AMPK1_CBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050827">
        <property type="entry name" value="CRP1_MDG1_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10343">
        <property type="entry name" value="5'-AMP-ACTIVATED PROTEIN KINASE , BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10343:SF84">
        <property type="entry name" value="5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16561">
        <property type="entry name" value="AMPK1_CBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AMP-activated protein kinase glycogen-binding" evidence="2">
        <location>
            <begin position="18"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="237" mass="27755" checksum="13452516DE509824" modified="2017-02-15" version="1">MLSTQNTKKDLKNEKELIPCLFSWCEGGREVYLVGSFINWDMNKKLKMDKCNGEFLLTLLLEKEIYTYKFLVDGQLKCSSSVATMRNSNGDINNVVDMKNYIPFNFELKKDQIFQCYKKIWKYSKQNNFDIVSRITPIPLYLENSRDIIKLNLSTPSFLSESLCNHMYFDTDSYKNYSSNIIEVCVVVKSEYNCKKGEKRKILTKYNILSYFPTSKNDDFVGSPSYNPLKHLISFNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRR1</accession>
    <name>A0A1J1GRR1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">MSF1-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00236300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527779.1">
        <property type="nucleotide sequence ID" value="XM_028671093.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRR1"/>
    <dbReference type="GeneID" id="39730891"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00236300"/>
    <dbReference type="OrthoDB" id="407630at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="72" mass="8403" checksum="CE5B6F87AA1CC1B8" modified="2017-02-15" version="1" fragment="single">ETQTYYKQSTTLNINGLGYMKNLIENTIINTIKEKSKQGIHIMNDTIKKTINDNININNNNIYIDNLEKEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS01</accession>
    <name>A0A1J1GS01_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00245300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527867.1">
        <property type="nucleotide sequence ID" value="XM_028671190.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS01"/>
    <dbReference type="GeneID" id="39730981"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00245300"/>
    <dbReference type="OMA" id="CTFEYDH"/>
    <dbReference type="OrthoDB" id="391995at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="613" mass="73285" checksum="FB12A0ACA83E7D14" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS16</accession>
    <name>A0A1J1GS16_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00246900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527883.1">
        <property type="nucleotide sequence ID" value="XM_028671208.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS16"/>
    <dbReference type="GeneID" id="39730997"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00246900"/>
    <dbReference type="OMA" id="TKLTNHD"/>
    <dbReference type="OrthoDB" id="371034at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="614" mass="74384" checksum="7FBF4E3AB0A276ED" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS53</accession>
    <name>A0A1J1GS53_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">phosphatidate phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00002500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the lipin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.4" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528071.1">
        <property type="nucleotide sequence ID" value="XM_028671416.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS53"/>
    <dbReference type="GeneID" id="39728547"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00002500"/>
    <dbReference type="OMA" id="DHRAYIS"/>
    <dbReference type="OrthoDB" id="4567at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008195">
        <property type="term" value="F:phosphatidate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026058">
        <property type="entry name" value="LIPIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031703">
        <property type="entry name" value="Lipin_mid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007651">
        <property type="entry name" value="Lipin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013209">
        <property type="entry name" value="LNS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031315">
        <property type="entry name" value="LNS2/PITP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12181">
        <property type="entry name" value="LIPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12181:SF12">
        <property type="entry name" value="PHOSPHATIDATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16876">
        <property type="entry name" value="Lipin_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04571">
        <property type="entry name" value="Lipin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08235">
        <property type="entry name" value="LNS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00775">
        <property type="entry name" value="LNS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LNS2/PITP" evidence="6">
        <location>
            <begin position="696"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="164"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="348"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="166"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="184"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="348"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="911" mass="106841" checksum="69AF9A11C1D944EA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS76</accession>
    <name>A0A1J1GS76_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="4">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">PGAL8A_00011400</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528158.1">
        <property type="nucleotide sequence ID" value="XM_028671513.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS76"/>
    <dbReference type="GeneID" id="39728636"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00011400"/>
    <dbReference type="OMA" id="RYILIIW"/>
    <dbReference type="OrthoDB" id="9984778at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23117">
        <property type="entry name" value="RING-H2_TUL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021319">
        <property type="entry name" value="DUF2921"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050731">
        <property type="entry name" value="HRD1_E3_ubiq-ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22763">
        <property type="entry name" value="RING ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22763:SF162">
        <property type="entry name" value="TRANSMEMBRANE E3 UBIQUITIN-PROTEIN LIGASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11145">
        <property type="entry name" value="DUF2921"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="500"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="554"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="600"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="641"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="17">
        <location>
            <begin position="696"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="353"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="368"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="CRG95347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="745" mass="88241" checksum="CBE6AEAC9E41C826" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSA1</accession>
    <name>A0A1J1GSA1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Rhomboid protease ROM6, putative</fullName>
            <ecNumber evidence="9">3.4.21.105</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ROM6</name>
        <name evidence="9" type="ORF">PGAL8A_00256300</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.105" evidence="9"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527971.1">
        <property type="nucleotide sequence ID" value="XM_028671305.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSA1"/>
    <dbReference type="GeneID" id="39731091"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00256300"/>
    <dbReference type="OMA" id="MWAFHTI"/>
    <dbReference type="OrthoDB" id="418595at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050925">
        <property type="entry name" value="Rhomboid_protease_S54"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43731:SF14">
        <property type="entry name" value="PRESENILIN-ASSOCIATED RHOMBOID-LIKE PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43731">
        <property type="entry name" value="RHOMBOID PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="203"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="313"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="337"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="396"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S54 rhomboid" evidence="8">
        <location>
            <begin position="296"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG95158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="502" mass="60132" checksum="E77A2A6622142256" modified="2017-02-15" version="1">MFRPHSFLKISYKKFFFHFNDKRCIYNFTKKKKIKNNVLKRKDRIKKEKNIKLKEKLKIIFFSSIYFFSVDFIYHVYILKDKNESNSVNEEKKNINEKKEVLASYLNKVNILNKGCNTKSEPIQNEKIRNNEKKEIKIIQSNEDPYEIKINRIKRKDGDENYIEKELINKKNQIFGYNENNKMKNQENNIKDTIVNNCYRQPFLNGCNLFLLVNGVVFLSWRLSELIKNKKLYHFMNRHFICSYDNIKKKYYHTILTASISHITFPHFLFNMWAFHTITNALLSPEIKENKKSYLFFNYKSNILEKKINDKDIINICVLSSLLSTIPYIFLNKKNKILGASGAIMGLIYILSTVKPNEVFISIFPFPYLKLSSLQLCHLTIFTNFLFLFFKRNFFSVAWSAHLFGLLGGVFYNIYQRKNKNFNYYPFIELSLKNGYIDYLNSYLDFIDMMKCLQLRTKLFFSLDQNSIKILNKKIHTIKMLQSQRRLKFNIQKMKNLENMSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSC2</accession>
    <name>A0A1J1GSC2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00260900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528017.1">
        <property type="nucleotide sequence ID" value="XM_028671357.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSC2"/>
    <dbReference type="GeneID" id="39731138"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00260900"/>
    <dbReference type="OMA" id="KNHNIFR"/>
    <dbReference type="OrthoDB" id="371738at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="177" mass="21263" checksum="8A5D659AE266A71A" modified="2017-02-15" version="1">MKSKVLYFLLFYNLILFCYTLKIRYIKNQVNSHFLCYIKKGNYLNSSNKHFYIRKKNISNNKFNLNEKKEDDILPFINNSKNHNIFRNKYNYIPSVDEVKSDIENFKKEKSFYFTEHSILELINIEDNIVVINIEGKFFEDINVVFTEITKYLLDKYLGILGVHPYNIKSLNINNEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSI8</accession>
    <name>A0A1J1GSI8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Acyl carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00016500</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Carrier of the growing fatty acid chain in fatty acid biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acyl carrier protein (ACP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528207.1">
        <property type="nucleotide sequence ID" value="XM_028671568.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSI8"/>
    <dbReference type="GeneID" id="39728687"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00016500"/>
    <dbReference type="OMA" id="EHFKITI"/>
    <dbReference type="OrthoDB" id="448946at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000035">
        <property type="term" value="F:acyl binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000036">
        <property type="term" value="F:acyl carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.10:FF:000003">
        <property type="entry name" value="Acyl carrier protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01217">
        <property type="entry name" value="Acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003231">
        <property type="entry name" value="ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00517">
        <property type="entry name" value="acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002148">
        <property type="entry name" value="PRK00982.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002150">
        <property type="entry name" value="PRK00982.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20863">
        <property type="entry name" value="ACYL CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20863:SF76">
        <property type="entry name" value="CARRIER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="ACP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4 9" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="3 9" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012814265" description="Acyl carrier protein" evidence="10">
        <location>
            <begin position="17"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Carrier" evidence="11">
        <location>
            <begin position="58"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG95396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="134" mass="15521" checksum="D574FDF8273465EF" modified="2017-02-15" version="1">MKILLLCIFFLYYVNAFKNTLKGDVSFKMYKRRKSDINFRNIKNNSSTFRRNTNSSLKSTFDDIKKITSKQLSVEEDKIKLESSFTKDLGADSLDLVELIMALEEKFNITISDADALKINTVQDAIDFIEKNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSJ0</accession>
    <name>A0A1J1GSJ0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00269400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000039">
        <property type="protein sequence ID" value="CRG95493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528302.1">
        <property type="nucleotide sequence ID" value="XM_028671673.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731225"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00269400"/>
    <dbReference type="OrthoDB" id="348930at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="284"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="354"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="482"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="598"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="784"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1133"/>
            <end position="1194"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1696"/>
            <end position="1723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="289"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="308"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="354"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="489"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="607"/>
            <end position="628"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1951" mass="227761" checksum="BBA70FAFFA48BBCF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSK4</accession>
    <name>A0A1J1GSK4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00021700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528258.1">
        <property type="nucleotide sequence ID" value="XM_028671624.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSK4"/>
    <dbReference type="GeneID" id="39728739"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00021700"/>
    <dbReference type="OMA" id="MGDETGC"/>
    <dbReference type="OrthoDB" id="372613at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="607"/>
            <end position="665"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1101" mass="132002" checksum="A143416DE1D6E2E1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSN9</accession>
    <name>A0A1J1GSN9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00269100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000039">
        <property type="protein sequence ID" value="CRG95489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528298.1">
        <property type="nucleotide sequence ID" value="XM_028671669.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731221"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00269100"/>
    <dbReference type="OMA" id="WIENETM"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="653"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="218"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="430"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="934"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1533"/>
            <end position="1573"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="122"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1029"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1129"/>
            <end position="1156"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1337"/>
            <end position="1371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="248"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="277"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="315"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="431"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="442"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
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            <end position="954"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
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            <begin position="966"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
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            <begin position="1537"/>
            <end position="1550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
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            <begin position="1551"/>
            <end position="1561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1562"/>
            <end position="1573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1573" mass="184555" checksum="7EAC9B5FDBFA3AF1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSW8</accession>
    <name>A0A1J1GSW8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00277500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528386.1">
        <property type="nucleotide sequence ID" value="XM_028671767.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSW8"/>
    <dbReference type="GeneID" id="39731308"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00277500"/>
    <dbReference type="OMA" id="RNNDCPL"/>
    <dbReference type="OrthoDB" id="378752at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16454">
        <property type="entry name" value="RING-H2_PA-TM-RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052788">
        <property type="entry name" value="RING-type_E3_ligase_ATL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45798:SF97">
        <property type="entry name" value="ALCOHOL-SENSITIVE RING FINGER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45798">
        <property type="entry name" value="RING-H2 FINGER PROTEIN ATL61-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="326"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="374"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="660"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="115"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="557"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="141"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="561"/>
            <end position="609"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="719" mass="83942" checksum="9A20E445BFDC43B0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT09</accession>
    <name>A0A1J1GT09_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Transmission-blocking target antigen s230 paralog, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">P230p</name>
        <name evidence="11" type="ORF">PGAL8A_00016100</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cell surface</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528203.1">
        <property type="nucleotide sequence ID" value="XM_028671563.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728683"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00016100"/>
    <dbReference type="OMA" id="FYCTCED"/>
    <dbReference type="OrthoDB" id="381130at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2860">
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010884">
        <property type="entry name" value="6_CYS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038160">
        <property type="entry name" value="6_CYS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051444">
        <property type="entry name" value="Parasite_Repro/Invasion_Surf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38796">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38796:SF1">
        <property type="entry name" value="ANCHORED PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G09600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07422">
        <property type="entry name" value="s48_45"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00970">
        <property type="entry name" value="s48_45"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51701">
        <property type="entry name" value="6_CYS"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="5"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="10">
        <location>
            <begin position="554"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="10">
        <location>
            <begin position="696"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="10">
        <location>
            <begin position="900"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="10">
        <location>
            <begin position="1063"/>
            <end position="1227"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="10">
        <location>
            <begin position="1232"/>
            <end position="1360"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="10">
        <location>
            <begin position="1384"/>
            <end position="1581"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="10">
        <location>
            <begin position="1584"/>
            <end position="1731"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="10">
        <location>
            <begin position="2073"/>
            <end position="2197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG95392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2223" mass="258537" checksum="73843AEE6B4AA292" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTJ0</accession>
    <name>A0A1J1GTJ0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Leucine-rich repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">LRR5</name>
        <name evidence="4" type="ORF">PGAL8A_00304000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528636.1">
        <property type="nucleotide sequence ID" value="XM_028672044.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731573"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00304000"/>
    <dbReference type="OMA" id="HYCKINS"/>
    <dbReference type="OrthoDB" id="6334211at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18849:SF0">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 410-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18849">
        <property type="entry name" value="LEUCINE RICH REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14580">
        <property type="entry name" value="LRR_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52075">
        <property type="entry name" value="Outer arm dynein light chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="14"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1386"/>
            <end position="1416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1386"/>
            <end position="1396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1397"/>
            <end position="1408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1452" mass="173702" checksum="D4823DF65C92DDFC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTL7</accession>
    <name>A0A1J1GTL7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosome biogenesis protein BOP1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">BOP1</name>
        <name evidence="9" type="ORF">PGAL8A_00277600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Nucleus</location>
            <location evidence="6">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the WD repeat BOP1/ERB1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528387.1">
        <property type="nucleotide sequence ID" value="XM_028671768.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTL7"/>
    <dbReference type="GeneID" id="39731309"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00277600"/>
    <dbReference type="OMA" id="MRPAKGE"/>
    <dbReference type="OrthoDB" id="5571054at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070545">
        <property type="term" value="C:PeBoW complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043021">
        <property type="term" value="F:ribonucleoprotein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000466">
        <property type="term" value="P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03027">
        <property type="entry name" value="BOP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028598">
        <property type="entry name" value="BOP1/Erb1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012953">
        <property type="entry name" value="BOP1_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17605:SF0">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BOP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17605">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BOP1 BLOCK OF PROLIFERATION 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08145">
        <property type="entry name" value="BOP1NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01035">
        <property type="entry name" value="BOP1NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="BOP1 N-terminal" evidence="8">
        <location>
            <begin position="182"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="555"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="582"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG95579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="907" mass="108170" checksum="87E1FB108FE37259" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU25</accession>
    <name>A0A1J1GU25_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00193500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000029">
        <property type="protein sequence ID" value="CRG94537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527352.1">
        <property type="nucleotide sequence ID" value="XM_028670617.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU25"/>
    <dbReference type="GeneID" id="39730460"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00193500"/>
    <dbReference type="OMA" id="DVMYDEN"/>
    <dbReference type="OrthoDB" id="10620428at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="356"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="416" mass="50151" checksum="26E080C44D27F156" modified="2017-02-15" version="1">MLKINANNFKFIKVLLRRKHLVVFLINLIIILYVNKKTTKDIYNFKNYLNQIYYLDKKNDNIPIIKVVKKTNESRNRFNLYLMNYRNGAINFIKDNQIFEILKKKVYIEKNKVYNFMLFLRIITHNILIKKNENFGLQIILTENNSLKSCIIDKETSKKKQLIKSRILLSLSRRRRGNKVSKRNSSKKKKSKSRRKSKKKKRKRKGKSKKARKKKKKRESRRRKKRKNRERKRQRLRNKEEDEDDDEEEEGEEEEEENDLQLRNSDEENGRRNMKSVEKVNMKESNNSRSKQDEDEDRPPRNRIKKSTARETDEEENKRSRNIGRRAGDENANIKSAKRKRMADEDESDELESTNRKPKKLRRHRRREQTENADDDDDERENVNKAIDELSSKKELLEKAESNLTQLLKSIHMLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU62</accession>
    <name>A0A1J1GU62_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosomal protein L20, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00197200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527392.1">
        <property type="nucleotide sequence ID" value="XM_028670662.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU62"/>
    <dbReference type="GeneID" id="39730499"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00197200"/>
    <dbReference type="OMA" id="GRRKNVW"/>
    <dbReference type="OrthoDB" id="10251781at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1900.20">
        <property type="entry name" value="Ribosomal protein L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005813">
        <property type="entry name" value="Ribosomal_bL20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035566">
        <property type="entry name" value="Ribosomal_protein_bL20_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01032">
        <property type="entry name" value="rplT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10986">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00453">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00062">
        <property type="entry name" value="RIBOSOMALL20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74731">
        <property type="entry name" value="Ribosomal protein L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="121" mass="14710" checksum="4F6344D4B770C453" modified="2017-02-15" version="1">MKLPREVVFQVAKGFRGRSKGCFKIARSRAMKALLYSYIMRRQRYRRLRVHWIASINRACREWKFTYAHFTNSLLNNNILLNRKSLYNLCYTEPISFKSLVDESKYIFFQRKLKFRDISQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUA2</accession>
    <name>A0A1J1GUA2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">GTP-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00201400</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527432.1">
        <property type="nucleotide sequence ID" value="XM_028670706.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUA2"/>
    <dbReference type="GeneID" id="39730540"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00201400"/>
    <dbReference type="OMA" id="AKPCLLC"/>
    <dbReference type="OrthoDB" id="391988at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01876">
        <property type="entry name" value="YihA_EngB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00321">
        <property type="entry name" value="GTPase_EngB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030393">
        <property type="entry name" value="G_ENGB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019987">
        <property type="entry name" value="GTP-bd_ribosome_bio_YsxC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03598">
        <property type="entry name" value="GTPase_YsxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11649:SF13">
        <property type="entry name" value="ENGB-TYPE G DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11649">
        <property type="entry name" value="MSS1/TRME-RELATED GTP-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51706">
        <property type="entry name" value="G_ENGB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0717">Septation</keyword>
    <feature type="domain" description="EngB-type G" evidence="12">
        <location>
            <begin position="109"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="711"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="238"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="726"/>
            <end position="740"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG94617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="924" mass="109582" checksum="1D1CDBC25F8E4F78" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUC9</accession>
    <name>A0A1J1GUC9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Apicoplast ribosomal protein S15, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00333400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528924.1">
        <property type="nucleotide sequence ID" value="XM_028672364.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUC9"/>
    <dbReference type="GeneID" id="39731864"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00333400"/>
    <dbReference type="OMA" id="LTFKIYF"/>
    <dbReference type="OrthoDB" id="364880at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00353">
        <property type="entry name" value="Ribosomal_S15p_S13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01343_B">
        <property type="entry name" value="Ribosomal_uS15_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000589">
        <property type="entry name" value="Ribosomal_uS15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005290">
        <property type="entry name" value="Ribosomal_uS15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="uS15_NS1_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00952">
        <property type="entry name" value="S15_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23321">
        <property type="entry name" value="RIBOSOMAL PROTEIN S15, BACTERIAL AND ORGANELLAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23321:SF26">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US15M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00312">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01387">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="S15/NS1 RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="86"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="274" mass="33089" checksum="36F2A8C0D7E741D6" modified="2017-02-15" version="1">MKKIKSCLIISLLFYLQILYKFLFCNGFYVGHKINFLINKRTTKYTYKKKFNGNKFFKKSSYNENTVDKLSSLDDSTTTNNEEHIKPDIKKNYDKLKENIEKQKVQIDEILKKSKSIHLERSFSFNKDDIMIKPELLKDLITQKYRKLFQRHDKDCGSSEIQIIILTFKIYFLTEHMKKNKKDFACLRGLFKCVSKRRKLLIYLGMKNREIFDKITDFFKIKKPLLPRTPEYYSKDLKYIHFKNTKRFKNNAEKKKKDKLKKKKEQTDKILFSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUP3</accession>
    <name>A0A1J1GUP3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00317600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528771.1">
        <property type="nucleotide sequence ID" value="XM_028672193.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUP3"/>
    <dbReference type="GeneID" id="39731709"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00317600"/>
    <dbReference type="OMA" id="HYFHLFY"/>
    <dbReference type="OrthoDB" id="377144at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033063">
        <property type="term" value="C:Rad51B-Rad51C-Rad51D-XRCC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033065">
        <property type="term" value="C:Rad51C-XRCC3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005657">
        <property type="term" value="C:replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction DNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000400">
        <property type="term" value="F:four-way junction DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000707">
        <property type="term" value="P:meiotic DNA recombinase assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052093">
        <property type="entry name" value="HR_Repair_Mediator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46239:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD51 HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46239">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD51 HOMOLOG 3 RAD51C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="475" mass="57296" checksum="9AF1F11F89B2AE0E" modified="2017-02-15" version="1">MVTKKNVSHEKIISPVISKLDIKPVKIKNLYELNKELKNKIYTNIYSYNTLCDGIFICRGINGITGTKNSGKTSLSSHISVNLYFNDLLHFFHLFYSTYFAFENFLKNRNIEIKFFLQSGNNLNKIKKEFNSSNKTFYELNELIKYFTLLFIEKYDKKIDGSEFYLNNNKKVNESSNLFSKRKVIYLDLDNSFYIERYKNMIYSSIDKIKKLMNTYMGFCSERHSFLFLLLLENNDLKKNLFHIYKNYSNEYFLFINLFNHYLKKYIYDITFLDVFKNLQILKIFSFNELINVVNYIYQQLQNYSVRSTNYFNKYVSSDLGILVVDNLNYLYKSYEFNHDLNNELINLLKILSKISTKYKICVLITNNENKYLKKYDKYFNKIYSKYIYNRIVVRFINKKFFFEYNYSAKKQKQFQNKSITNSSSEESFYEIGENDEETFYEKRYNLRYIKVKKKNKINICSFEINEHGVQTLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUS0</accession>
    <name>A0A1J1GUS0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00326300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000053">
        <property type="protein sequence ID" value="CRG96049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528857.1">
        <property type="nucleotide sequence ID" value="XM_028672290.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUS0"/>
    <dbReference type="GeneID" id="39731795"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00326300"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="220" mass="26036" checksum="93D922DD744C421D" modified="2017-02-15" version="1" fragment="single">MKTLTLFLRITTFHLLIWMYQCFYNCYSYKTWIDENILQTKNELKYERILTEGNTEEKKQTNAEGCLKERPLDNEKNKCKNLIQYKNPYDPCHGANTSSLSESFDRKAKEMNPKLRDQKLNIECNKISANQVSDPHFISHGPDIPDEEKSKITDSVKNQHDFKLDERLCESNKKMKDNKTESESNKEMIDNKAESESKKEQGKKKKKNKKFDLMKHLIFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUU2</accession>
    <name>A0A1J1GUU2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Large ribosomal subunit processing factor, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00353100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529118.1">
        <property type="nucleotide sequence ID" value="XM_028672580.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUU2"/>
    <dbReference type="GeneID" id="39732061"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00353100"/>
    <dbReference type="OMA" id="EYAYFVN"/>
    <dbReference type="OrthoDB" id="366094at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="67"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="152"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="199" mass="23985" checksum="BF5335155F2C430E" modified="2017-02-15" version="1">MINFTSPHTNDPIKKLQNLLNNCLHSIIDVFSNLSYKGEYKELEIEPEESSEYSYFINLLKERENKNKEEIKDEKETNNEKETNDEKQTNDEKQTNDELEPLNKDEEKNYFIKPKFEKSLKEEILDRVERMNLILKTIDECIDELPDSLIIEEEKCKEIKMLQKKKDAAKDELKNLYNEYDYIYNYVTYYLRDLITNIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUX3</accession>
    <name>A0A1J1GUX3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Palmitoyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">DHHC3</name>
        <name evidence="9" type="ORF">PGAL8A_00347600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529063.1">
        <property type="nucleotide sequence ID" value="XM_028672518.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUX3"/>
    <dbReference type="GeneID" id="39732006"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00347600"/>
    <dbReference type="OMA" id="ICGFVEP"/>
    <dbReference type="OrthoDB" id="1924421at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883:SF203">
        <property type="entry name" value="PALMITOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883">
        <property type="entry name" value="ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="151"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="197"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="8">
        <location>
            <begin position="107"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG96258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="291" mass="34651" checksum="0DC35CFDBB871075" modified="2017-02-15" version="1">MNKRIFTLRDDTRSKEADEFVRKNGFTLPLQFFQLMSFLIYIVIIALIILITAFNTDTIFILFYIFFGFLIITIFVLSYTVTKINPIDPLSFKYINNKINDEDVKDLCHCDICGFVEPKSKHCKVCNKCVSVFDHHCMWVNNCIGKKNYKYFVGLLTVLTIFNCFVFVFCIVYFINSLKYDFIKDRWKNSYGSYNDILFYILLCSLFILNGTVFILVIQLFALHIFLISKKMTTYEYILNRANESEKKEKKTVKTFFEWIIIDKKRLKKSKNKNQDIENQEIERDMTIKNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUX7</accession>
    <name>A0A1J1GUX7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00250600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527917.1">
        <property type="nucleotide sequence ID" value="XM_028671246.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUX7"/>
    <dbReference type="GeneID" id="39731034"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00250600"/>
    <dbReference type="OMA" id="VQDENYS"/>
    <dbReference type="OrthoDB" id="371589at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="338"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="405"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="447" mass="54207" checksum="ADAF820033CF3B15" modified="2017-02-15" version="1">MNRLVKRSNFFFCVFKNDMKTLINKNVDYEFIKTINKKKKEKSFKNIFFAVGLTNLAIFFYTFQNFYSKKNKDYFHFNDITVVDHFILSEFISSIGINNFHVYLKNNFYKKLTTQLQNESYSFKENSLLGLLENLCKNKNTFIEIEKKKKEFDLLTYIFEKLKNEYLEYTKKKIYSCILFYYIKYSDELFFTYDQIQQLVYNKNLFYNLKNKEEIISYLLLLIFKNEKNIYEIYEKENELIKIYTQNNNQLNKVTENYNNSIIKFLISSKNNNKINEQSILKFYYSIKKNNENYYKQESLRKFQNYLNKINAPLLINENDLVKEKNSNNIMNKIYLKYFENTILYTFFFSFILHNINAKEYNLKTYITAFKDIYKSIYTNCIINSLFLIEKSVINNLDIHKDTNLFLLISFLFNILNSLSFSFSIYKCKYALVPLLFSQIIKDDFFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUY3</accession>
    <name>A0A1J1GUY3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Histone H4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00332300</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 10">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the histone H4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528913.1">
        <property type="nucleotide sequence ID" value="XM_028672352.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUY3"/>
    <dbReference type="SMR" id="A0A1J1GUY3"/>
    <dbReference type="GeneID" id="39731853"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00332300"/>
    <dbReference type="OMA" id="QKEHING"/>
    <dbReference type="OrthoDB" id="10255923at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22912">
        <property type="entry name" value="HFD_H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000002">
        <property type="entry name" value="Histone H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035425">
        <property type="entry name" value="CENP-T/H4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001951">
        <property type="entry name" value="Histone_H4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019809">
        <property type="entry name" value="Histone_H4_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004823">
        <property type="entry name" value="TAF_TATA-bd_Histone-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10484">
        <property type="entry name" value="HISTONE H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15511">
        <property type="entry name" value="CENP-T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00623">
        <property type="entry name" value="HISTONEH4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00417">
        <property type="entry name" value="H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00803">
        <property type="entry name" value="TAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00047">
        <property type="entry name" value="HISTONE_H4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 10" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="8 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TATA box binding protein associated factor (TAF) histone-like fold" evidence="12">
        <location>
            <begin position="28"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG96108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="103" mass="11456" checksum="7ADC420E2CB12350" modified="2017-02-15" version="1">MSGRGKGGKGLGKGGAKRHRKILRDNIQGITKPAIRRLARRGGVKRISGLIYEEIRGVLKVFLENVIKDSIMYTEHAKRKTVTAMDIVYSLKRQGRTLYGFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVA7</accession>
    <name>A0A1J1GVA7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00365400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529234.1">
        <property type="nucleotide sequence ID" value="XM_028672708.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVA7"/>
    <dbReference type="GeneID" id="39732184"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00365400"/>
    <dbReference type="OMA" id="ENSDLYM"/>
    <dbReference type="OrthoDB" id="370418at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="500"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="419"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="699" mass="83649" checksum="95B654B34C345FE8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVK4</accession>
    <name>A0A1J1GVK4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">SANT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00349600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529083.1">
        <property type="nucleotide sequence ID" value="XM_028672541.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732026"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00349600"/>
    <dbReference type="OMA" id="FAWGILP"/>
    <dbReference type="OrthoDB" id="10258692at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SANT" evidence="4">
        <location>
            <begin position="1071"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="3">
        <location>
            <begin position="1906"/>
            <end position="1951"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="129"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="686"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1537"/>
            <end position="1585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1599"/>
            <end position="1722"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="248"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="136"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="703"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1599"/>
            <end position="1611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1612"/>
            <end position="1643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1651"/>
            <end position="1685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1686"/>
            <end position="1700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1701"/>
            <end position="1722"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1966" mass="234970" checksum="154B6A9A742BB9C2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW83</accession>
    <name>A0A1J1GW83_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mitochondrial ribosomal protein L16, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00276200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528373.1">
        <property type="nucleotide sequence ID" value="XM_028671751.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW83"/>
    <dbReference type="GeneID" id="39731294"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00276200"/>
    <dbReference type="OMA" id="MPMATKF"/>
    <dbReference type="OrthoDB" id="268521at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01433">
        <property type="entry name" value="Ribosomal_L16_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.10">
        <property type="entry name" value="Ribosomal protein L10e/L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047873">
        <property type="entry name" value="Ribosomal_uL16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000114">
        <property type="entry name" value="Ribosomal_uL16_bact-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016180">
        <property type="entry name" value="Ribosomal_uL16_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036920">
        <property type="entry name" value="Ribosomal_uL16_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12220">
        <property type="entry name" value="50S/60S RIBOSOMAL PROTEIN L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12220:SF13">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL16M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00252">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54686">
        <property type="entry name" value="Ribosomal protein L16p/L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="183" mass="20750" checksum="EA8C07470EA95742" modified="2017-02-15" version="1">MPPVIYKSPLPVRLKAPKGRIIPLNAPDIKIGKSLISACPKRIKGEKLAEMRQIIRKYLGKKKEYFVDVHATYSVTKKPDGTKMGQGKGVIDHFVARVPSGKTIFHIPTISPFNALGFDDPVYKVLKKAAAKVAIPCVFRTQNNLFRVHNIKYISQKKIRSDQLKQFKEYKSKLFKNDSENNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWJ7</accession>
    <name>A0A1J1GWJ7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">60S ribosomal protein L37ae, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00015000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528192.1">
        <property type="nucleotide sequence ID" value="XM_028671551.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWJ7"/>
    <dbReference type="GeneID" id="39728672"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00015000"/>
    <dbReference type="OMA" id="EAMKRTC"/>
    <dbReference type="OrthoDB" id="10258345at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00327">
        <property type="entry name" value="Ribosomal_eL43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011331">
        <property type="entry name" value="Ribosomal_eL37/eL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002674">
        <property type="entry name" value="Ribosomal_eL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050522">
        <property type="entry name" value="Ribosomal_protein_eL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00280">
        <property type="entry name" value="eL43_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48129">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L37A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48129:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01780">
        <property type="entry name" value="Ribosomal_L37ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="96" mass="10803" checksum="B6ECEF48D8830171" modified="2017-02-15" version="1">MSRRTKKVGLTGKYGTRYGSSLRKQMKKIELMQHAKYLCSFCGKTATKRTCVGIWQCKKCKRKVCGGAWSLTTPAAVAAKSTIIRLRKQKEEAQKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWL9</accession>
    <name>A0A1J1GWL9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Guanylate kinase</fullName>
            <ecNumber evidence="4">2.7.4.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">GMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">GK</name>
        <name evidence="15" type="ORF">PGAL8A_00441700</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Essential for recycling GMP and indirectly, cGMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>GMP + ATP = GDP + ADP</text>
            <dbReference type="Rhea" id="RHEA:20780"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the guanylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.8" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529639.1">
        <property type="nucleotide sequence ID" value="XM_028673158.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWL9"/>
    <dbReference type="GeneID" id="39732950"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00441700"/>
    <dbReference type="OMA" id="NFITHEV"/>
    <dbReference type="OrthoDB" id="6334211at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004385">
        <property type="term" value="F:GMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00071">
        <property type="entry name" value="GMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.63.10:FF:000005">
        <property type="entry name" value="Guanylate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.63.10">
        <property type="entry name" value="Guanylate Kinase phosphate binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008145">
        <property type="entry name" value="GK/Ca_channel_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008144">
        <property type="entry name" value="Guanylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017665">
        <property type="entry name" value="Guanylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020590">
        <property type="entry name" value="Guanylate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03263">
        <property type="entry name" value="guanyl_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23117:SF13">
        <property type="entry name" value="GUANYLATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23117">
        <property type="entry name" value="GUANYLATE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00625">
        <property type="entry name" value="Guanylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00072">
        <property type="entry name" value="GuKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00856">
        <property type="entry name" value="GUANYLATE_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50052">
        <property type="entry name" value="GUANYLATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Guanylate kinase-like" evidence="14">
        <location>
            <begin position="4"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="133"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG96836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="195" mass="23362" checksum="7F243EFBE3306F81" modified="2017-02-15" version="1">MKKIAPLIICGPSGVGKGTLIKKLLEEFPQFFRFSVSCTTRKKREKEKNGIDYYFLNREDFEEKLKKNYFLEYDNYANNLYGTLKSEYDKAESEEKICLFEMNINGVKQLKNSDYIKDGIYIFVKPPSSDILLNRLRNRNTENQEQINKRMEELKRELDEAYKIDFNFYIVNDDLTKTYEELKSFLMKSYEYLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWX8</accession>
    <name>A0A1J1GWX8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Elongation factor G, mitochondrial</fullName>
            <shortName evidence="8">EF-Gmt</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Elongation factor G 1, mitochondrial</fullName>
            <shortName evidence="8">mEF-G 1</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Elongation factor G1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">EF-G</name>
        <name evidence="10" type="ORF">PGAL8A_00454700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8">Protein biosynthesis; polypeptide chain elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529770.1">
        <property type="nucleotide sequence ID" value="XM_028673303.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWX8"/>
    <dbReference type="GeneID" id="39733080"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00454700"/>
    <dbReference type="OMA" id="GQFAKVQ"/>
    <dbReference type="OrthoDB" id="198619at2759"/>
    <dbReference type="UniPathway" id="UPA00345"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070125">
        <property type="term" value="P:mitochondrial translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01886">
        <property type="entry name" value="EF-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16262">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01434">
        <property type="entry name" value="EFG_mtEFG1_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03713">
        <property type="entry name" value="EFG_mtEFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.240:FF:000001">
        <property type="entry name" value="Elongation factor G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000022">
        <property type="entry name" value="Elongation factor G, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000013">
        <property type="entry name" value="Elongation factor G, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000514">
        <property type="entry name" value="Ribosome-releasing factor 2, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00054_B">
        <property type="entry name" value="EF_G_EF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053905">
        <property type="entry name" value="EF-G-like_DII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009022">
        <property type="entry name" value="EFG_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047872">
        <property type="entry name" value="EFG_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035649">
        <property type="entry name" value="EFG_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004540">
        <property type="entry name" value="Transl_elong_EFG/EF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43636">
        <property type="entry name" value="ELONGATION FACTOR G, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43636:SF2">
        <property type="entry name" value="ELONGATION FACTOR G, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22042">
        <property type="entry name" value="EF-G_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 10" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="7 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="9">
        <location>
            <begin position="39"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="48"/>
            <end position="55"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="119"/>
            <end position="123"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="173"/>
            <end position="176"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG96967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="777" mass="89469" checksum="A144854033604F6B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWY8</accession>
    <name>A0A1J1GWY8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-oxoacyl-[acyl-carrier-protein] reductase</fullName>
            <ecNumber evidence="2">1.1.1.100</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00435800</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17397"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="1.1.1.100"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529579.1">
        <property type="nucleotide sequence ID" value="XM_028673092.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWY8"/>
    <dbReference type="GeneID" id="39732890"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00435800"/>
    <dbReference type="OMA" id="LFGVQCD"/>
    <dbReference type="OrthoDB" id="1393670at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05333">
        <property type="entry name" value="BKR_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000115">
        <property type="entry name" value="3-oxoacyl-[acyl-carrier-protein] reductase FabG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011284">
        <property type="entry name" value="3oxo_ACP_reduc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057326">
        <property type="entry name" value="KR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050259">
        <property type="entry name" value="SDR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01830">
        <property type="entry name" value="3oxo_ACP_reduc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005559">
        <property type="entry name" value="PRK07231.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009464">
        <property type="entry name" value="PRK12824.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009466">
        <property type="entry name" value="PRK12826.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42879">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42879:SF2">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00822">
        <property type="entry name" value="PKS_KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012791742" description="3-oxoacyl-[acyl-carrier-protein] reductase" evidence="9">
        <location>
            <begin position="20"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="Ketoreductase" evidence="10">
        <location>
            <begin position="60"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="66"/>
            <end position="69"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="208"/>
            <end position="212"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR611284-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR611284-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG96776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="300" mass="32919" checksum="12C22EFF9D3DC4B3" modified="2017-02-15" version="1">MNFLNKCFIFFLFIKFLKSIKLSFISSNTKLIPHKCVSKNDAINLLNDKKENSYYCGENKVALITGAGRGIGRSIAKTLAKSVSHVLCISRTQKSCDSVVDELKSLGYKSAGYAADVSNKEEITDLVNKLLMDNKKIDILVNNAGITRDNLFMRMKNDEWEDVIKTNLNSLFYVTQPISKRMISNRYGRIINISSIVGLTGNFGQANYSASKAGVIGFTKTLAKELASRNITVNAIAPGFISSDMTDKINDQIKKDIISNIPAGRMGTPEEVANMVGYLASEIAGYINGRVFVIDGGLAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX06</accession>
    <name>A0A1J1GX06_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00437400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529595.1">
        <property type="nucleotide sequence ID" value="XM_028673109.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX06"/>
    <dbReference type="GeneID" id="39732906"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00437400"/>
    <dbReference type="OMA" id="YAIHAQI"/>
    <dbReference type="OrthoDB" id="365615at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053019">
        <property type="entry name" value="GATA_zinc_finger"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23353">
        <property type="entry name" value="RAB-GAP/TBC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="520"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="633"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="676"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="717"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="764"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="802"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="832"/>
            <end position="851"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="917" mass="109757" checksum="02310ADC4EBDC4AC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX21</accession>
    <name>A0A1J1GX21_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin-like modifier HUB1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">HUB1</name>
        <name evidence="3" type="ORF">PGAL8A_00459500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529818.1">
        <property type="nucleotide sequence ID" value="XM_028673358.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX21"/>
    <dbReference type="GeneID" id="39733128"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00459500"/>
    <dbReference type="OMA" id="GMSLEMQ"/>
    <dbReference type="OrthoDB" id="3881at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01791">
        <property type="entry name" value="Ubl_UBL5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000054">
        <property type="entry name" value="Ubiquitin-like protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039732">
        <property type="entry name" value="Hub1/Ubl5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13042">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="2"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="73" mass="8587" checksum="4D861927BAE8D7FC" modified="2017-02-15" version="1">MIEVILNDRLGKKIRVKCNPDDTIGDLKKLVAAQTGTRADKIRIQKWYIIYKDHITLQDYEIKDGMSLELYYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX27</accession>
    <name>A0A1J1GX27_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">U3 small nucleolar RNA-associated protein 11</fullName>
            <shortName evidence="5">U3 snoRNA-associated protein 11</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00468600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in nucleolar processing of pre-18S ribosomal RNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the ribosomal small subunit (SSU) processome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
            <location evidence="1 5">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the UTP11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529908.1">
        <property type="nucleotide sequence ID" value="XM_028673458.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX27"/>
    <dbReference type="GeneID" id="39733219"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00468600"/>
    <dbReference type="OrthoDB" id="29058at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007144">
        <property type="entry name" value="SSU_processome_Utp11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12838">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12838:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03998">
        <property type="entry name" value="Utp11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015952">
        <property type="entry name" value="U3snoRNP11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0698">rRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR015952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="212" mass="25590" checksum="09AF6E3FA04FE1FB" modified="2017-02-15" version="1">MSNFKNIVPKRSYLERGQPKHRLHLGELEKKVDYGKRREIYKKKKKIENVLKEKVMTKNPDEFHTGIVHSRITDNNILVKEKKVIKPEIQLKYKRNELIQKTNYLYNKLKKINKKISNYQINIPLRYIFNNSHELYNEDQIYTLKAENKKLRKKGECIQKEYNSLINAKNNILDNIRKLDNKYATTYRNIDGYKIINDKGKIPYRFYAPRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX28</accession>
    <name>A0A1J1GX28_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Pre-mRNA-splicing factor SYF1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">XAB2</name>
        <name evidence="12" type="ORF">PGAL8A_00457600</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the crooked-neck family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529799.1">
        <property type="nucleotide sequence ID" value="XM_028673337.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX28"/>
    <dbReference type="GeneID" id="39733109"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00457600"/>
    <dbReference type="OMA" id="PDKIKFY"/>
    <dbReference type="OrthoDB" id="10067343at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071007">
        <property type="term" value="C:U2-type catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000349">
        <property type="term" value="P:generation of catalytic spliceosome for first transesterification step"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055433">
        <property type="entry name" value="HAT_Syf1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056350">
        <property type="entry name" value="HAT_Syf1_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055430">
        <property type="entry name" value="HAT_Syf1_CNRKL1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045075">
        <property type="entry name" value="Syf1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246:SF5">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR SYF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23231">
        <property type="entry name" value="HAT_Syf1_CNRKL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23233">
        <property type="entry name" value="HAT_Syf1_CNRKL1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23220">
        <property type="entry name" value="HAT_Syf1_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Pre-mRNA-splicing factor Syf1-like N-terminal HAT-repeats" evidence="11">
        <location>
            <begin position="146"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="Pre-mRNA-splicing factor SYF1 central HAT repeats" evidence="9">
        <location>
            <begin position="280"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="Pre-mRNA-splicing factor Syf1/CRNKL1-like C-terminal HAT-repeats" evidence="10">
        <location>
            <begin position="579"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="410"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="420"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="480"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF23220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF23231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF23233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG96996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="985" mass="119770" checksum="8F60F3DE3EE99D77" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX58</accession>
    <name>A0A1J1GX58_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL23m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00460800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529831.1">
        <property type="nucleotide sequence ID" value="XM_028673372.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX58"/>
    <dbReference type="GeneID" id="39733141"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00460800"/>
    <dbReference type="OMA" id="RHQTIEY"/>
    <dbReference type="OrthoDB" id="275582at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013025">
        <property type="entry name" value="Ribosomal_uL23-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_uL23/eL15/eS24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12059:SF5">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL23M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12059">
        <property type="entry name" value="RIBOSOMAL PROTEIN L23-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00276">
        <property type="entry name" value="Ribosomal_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="Ribosomal proteins S24e, L23 and L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00039977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="270" mass="31878" checksum="6F27BC307EA6EA64" modified="2017-02-15" version="1">MFLSFIRLTPPKTPRNVFFPWHNFCVHKSGTFLEKNRLALRVPINLTKFEIREYLRKIYNAKVIKVNTLIKVPERRRNLSDRRFNYYRNGPRYKKAIVTLEHEVPDSVKMIQSCKNIGRNPYITKKNVIYGVRSDVKITPTRSQLWQMGECRYSWRLPLTNLLADYKMNLNPDLRIDEDFVQLQPDTTKPFMHSGISSETFKPNNVPEQKFPHIDLTPWRRQVKKIYDSGTLAPPEFFPQASKSIETIDYLNEGKNKKKSSRSSVWKPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXK9</accession>
    <name>A0A1J1GXK9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-CH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00461000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529833.1">
        <property type="nucleotide sequence ID" value="XM_028673374.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXK9"/>
    <dbReference type="GeneID" id="39733143"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00461000"/>
    <dbReference type="OMA" id="WRKTQKL"/>
    <dbReference type="OrthoDB" id="429628at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="205" mass="24132" checksum="5B31CBBDB23B06D8" modified="2017-02-15" version="1">MESNDYFMLSGNVNLKEPYIKNNNSEDKRELFCFICLEKDLENSVLLSCCSLCTACVHKKCWFTWRKTQKLGSLRSKLLGLNKSDPLLCTICKTGISKIEEENDFNWIVNNNRNKEYLQDELLRTIASLLNNENNDNNIPNVHFKYILSFNFIFLIILIIFIIFFIMVFGFTINYVLLIALLILYEVIVVQIVLYIYIRVKYNSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXS2</accession>
    <name>A0A1J1GXS2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Plasmepsin VII, putative</fullName>
            <ecNumber evidence="9">3.4.23.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00493300</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.23.-" evidence="9"/>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530156.1">
        <property type="nucleotide sequence ID" value="XM_028673733.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXS2"/>
    <dbReference type="GeneID" id="39733466"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00493300"/>
    <dbReference type="OMA" id="MGFWTID"/>
    <dbReference type="OrthoDB" id="771136at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase A1" evidence="8">
        <location>
            <begin position="71"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="300"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="6">
        <location>
            <begin position="103"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG97354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="449" mass="52092" checksum="0C7FC1C0AFDE238E" modified="2017-02-15" version="1">MNIIQVALKNGLSDIYLPSKINIENIRGLNLPLKKFNNLKKEFFLELKEVDDVILIKLNKQDIPSKKISTYYGQIAIGENPENYFNVLFDTGSSEFWIPFETCNSSQCNIHKKYKKSKTFKYKYDKKGLPSILEINYLSGKIIGFDGYERIKLGKNLIIPNTNISFATNIDIPILEDFKWDGIIGLGFENEDSRNRGIKPFLDHLAHENILKEKNYKNQFGYYLSDKEGFITFGGIDKKLKKSPEENVIWAPVSTDMGFWTIDILGIRKEKIINWEEKKDDELIVKYEGFHDGGRKSIVDTGTFLIYAPKNTMENYLSDLKINSCDDKFKLPYIIFQIRSKEISKVNGLAVMELTLSPDDYVIEYVDEVNSTKECIIGIQADEQFEEDRINGWTLGQVFLKSYYTIFDKDNLQIGFVRSKKNFFNDNYLKKSFLSLRTKKKIKNYNGPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXX0</accession>
    <name>A0A1J1GXX0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">U6 snRNA-associated Sm-like protein LSm4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 12" type="primary">LSM4</name>
        <name evidence="12" type="ORF">PGAL8A_00334300</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Binds specifically to the 3'-terminal U-tract of U6 snRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">LSm subunits form a heteromer with a doughnut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528933.1">
        <property type="nucleotide sequence ID" value="XM_028672374.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXX0"/>
    <dbReference type="GeneID" id="39731873"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00334300"/>
    <dbReference type="OMA" id="RGAFGNR"/>
    <dbReference type="OrthoDB" id="747253at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01723">
        <property type="entry name" value="LSm4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000048">
        <property type="entry name" value="U6 snRNA-associated Sm-like protein LSm4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034101">
        <property type="entry name" value="Lsm4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027141">
        <property type="entry name" value="LSm4/Sm_D1/D3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23338">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="11">
        <location>
            <begin position="3"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="88"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="91"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="109"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG96128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="121" mass="13834" checksum="876BAF6E4EE1D62B" modified="2017-02-15" version="1">MVFPLTLLKCSQNQPVMVELKNGETYSGFLVFCDRFMNLHMKNIICTSKDGDKFWKISECYVRGNSIKYIRVQDQAIEQAIEETTEQKLRNIGRGRGRGRGRGTDNRGGRGRAIRRGGRGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXX5</accession>
    <name>A0A1J1GXX5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">mRNA-decapping enzyme subunit 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">DCP1</name>
        <name evidence="6" type="ORF">PGAL8A_00491500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DCP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530138.1">
        <property type="nucleotide sequence ID" value="XM_028673713.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXX5"/>
    <dbReference type="GeneID" id="39733448"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00491500"/>
    <dbReference type="OMA" id="DQNYIFY"/>
    <dbReference type="OrthoDB" id="440673at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008047">
        <property type="term" value="F:enzyme activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031087">
        <property type="term" value="P:deadenylation-independent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09804">
        <property type="entry name" value="Dcp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010334">
        <property type="entry name" value="Dcp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16290:SF0">
        <property type="entry name" value="DECAPPING PROTEIN 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16290">
        <property type="entry name" value="TRANSCRIPTION FACTOR SMIF DECAPPING ENZYME DCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06058">
        <property type="entry name" value="DCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="371"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="374"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="884" mass="103388" checksum="410E7055B841F2C2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY64</accession>
    <name>A0A1J1GY64_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Meiosis-specific nuclear structural protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PGAL8A_00507300</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating. May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis. Required for sperm flagella assembly. May play a role in the assembly and function of the outer dynein arm-docking complex (ODA-DC). ODA-DC mediates outer dynein arms (ODA) binding onto the axonemal doublet microtubules.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Flagellum axoneme</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MNS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530301.1">
        <property type="nucleotide sequence ID" value="XM_028673894.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY64"/>
    <dbReference type="GeneID" id="39733606"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00507300"/>
    <dbReference type="OMA" id="MENIMQN"/>
    <dbReference type="OrthoDB" id="372986at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026504">
        <property type="entry name" value="MNS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043597">
        <property type="entry name" value="TPH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19265">
        <property type="entry name" value="MEIOSIS-SPECIFIC NUCLEAR STRUCTURAL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19265:SF0">
        <property type="entry name" value="MEIOSIS-SPECIFIC NUCLEAR STRUCTURAL PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13868">
        <property type="entry name" value="TPH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="7 14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="11" id="KW-0469">Meiosis</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Trichohyalin-plectin-homology" evidence="15">
        <location>
            <begin position="108"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="87"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="331"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00046114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF13868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="CRG97500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="472" mass="58062" checksum="4A80E738BF896838" modified="2017-02-15" version="1">MKRYNEKSITEKIQREQKNEYARERIKNELKLDNYSKLQGISIDKAEAAKKKNIEDSVKRECEVIDEFDITKIKEEKIRQCQLLSEKQKEEKEIADEKLREKALQHTMQNDEGYKKLKEKLEEIATLKERENQIKEAKLLKTKMEQEEEEKIEKQMENILIKEGKEEEKKKKLNYEKIMETKKELQEQIKENLKKKKEKYANNLEERSKMENIMQNYREEEKKKKEEGIQKQKKLLKEFQEQIELKNQRRELDKKKELEEEIKNQEYIKEKEEKIKDFLKKKVVKNLEKQKVVNELAYKEYLVNKDKEALDELLNKLYIEEHDFKEKQKDIKENEKKLQLKNEMLKQLEKDISLKEERRRKEKEEDEKRKIELLEEKKKLDKLDQYTDKKKKEKLQQYKKEIYESFQEKKNAVKNERLQEEIEKNKLLEEQKKYEELINQEKMKLIDKYKNDILEKLPEDIYEKLKKKNIIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYA2</accession>
    <name>A0A1J1GYA2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Kelch protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00481900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530043.1">
        <property type="nucleotide sequence ID" value="XM_028673607.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYA2"/>
    <dbReference type="GeneID" id="39733352"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00481900"/>
    <dbReference type="OMA" id="RIGFSTC"/>
    <dbReference type="OrthoDB" id="4447at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052588">
        <property type="entry name" value="Kelch_domain_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46063">
        <property type="entry name" value="KELCH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46063:SF1">
        <property type="entry name" value="KELCH DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="436"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="440"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="838" mass="99673" checksum="6DC9EBE05FF3C246" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYH4</accession>
    <name>A0A1J1GYH4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA topoisomerase (ATP-hydrolyzing)</fullName>
            <ecNumber evidence="4">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00486800</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the TOP6A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530091.1">
        <property type="nucleotide sequence ID" value="XM_028673661.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYH4"/>
    <dbReference type="GeneID" id="39733401"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00486800"/>
    <dbReference type="OMA" id="ICKSGIT"/>
    <dbReference type="OrthoDB" id="5377392at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000228">
        <property type="term" value="C:nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042138">
        <property type="term" value="P:meiotic DNA double-strand break formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000706">
        <property type="term" value="P:meiotic DNA double-strand break processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00223">
        <property type="entry name" value="TOPRIM_TopoIIB_SPO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1360.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002815">
        <property type="entry name" value="Spo11/TopoVI_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013049">
        <property type="entry name" value="Spo11/TopoVI_A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036078">
        <property type="entry name" value="Spo11/TopoVI_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034136">
        <property type="entry name" value="TOPRIM_Topo6A/Spo11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10848">
        <property type="entry name" value="MEIOTIC RECOMBINATION PROTEIN SPO11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10848:SF0">
        <property type="entry name" value="MEIOTIC RECOMBINATION PROTEIN SPO11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21180">
        <property type="entry name" value="TOP6A-Spo11_Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04406">
        <property type="entry name" value="TP6A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01550">
        <property type="entry name" value="TOP6AFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56726">
        <property type="entry name" value="DNA topoisomerase IV, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52041">
        <property type="entry name" value="TOPO_IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 10 13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Spo11/DNA topoisomerase VI subunit A N-terminal" evidence="11">
        <location>
            <begin position="54"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="Topoisomerase 6 subunit A/Spo11 TOPRIM" evidence="12">
        <location>
            <begin position="162"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="10">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF21180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG97289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="334" mass="39513" checksum="FCC2F0CCA0F5991C" modified="2017-02-15" version="1">MMNYKVIDKNKIYEAIEDFILHIISWLLNINVDIFKNNLDKNYSSNLFDKKLVKLCRTLSVVEIINNMIIQDKSCTQREIYYKLYNVFYEQSQTNRYIKEVCNILGFPRSTLNIYASEKGCIAGLLVLQKNNEILNLSEMNNGLMINECLLNVDKIDTLAHYIIVVEKYSLYQKLCQHKIWDILPCILITGKGFPDFSTRKILYQLIALFNLECAYVGDYDPYGIRIYLTYKEGNSTYENNICSCKNIKWIGMCSEDIKLFPKQSLLVLTKKEKKVIKNLLEDKNLNYSQIKKEVCEMEKMNYKFEIEAIEYLGMEFFIKKYLILKILRKQWLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYH5</accession>
    <name>A0A1J1GYH5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">RNA methyltransferase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00356200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529149.1">
        <property type="nucleotide sequence ID" value="XM_028672614.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYH5"/>
    <dbReference type="GeneID" id="39732092"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00356200"/>
    <dbReference type="OMA" id="DINKFRC"/>
    <dbReference type="OrthoDB" id="427002at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009383">
        <property type="term" value="F:rRNA (cytosine-C5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000470">
        <property type="term" value="P:maturation of LSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1170">
        <property type="entry name" value="Sun protein, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049560">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011023">
        <property type="entry name" value="Nop2p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018314">
        <property type="entry name" value="RsmB/NOL1/NOP2-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00446">
        <property type="entry name" value="nop2p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807:SF30">
        <property type="entry name" value="28S RRNA (CYTOSINE(4447)-C(5))-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807">
        <property type="entry name" value="NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01153">
        <property type="entry name" value="NOL1_NOP2_SUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 6 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM-dependent MTase RsmB/NOP-type" evidence="9">
        <location>
            <begin position="227"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="525"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="629"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="95"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="404"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="72"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="525"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="537"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="557"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="570"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="643"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="664"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="440"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="319"/>
            <end position="325"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="343"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="370"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="388"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG96344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="686" mass="80265" checksum="B63CA63EF5FB84B4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYQ1</accession>
    <name>A0A1J1GYQ1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA-directed RNA polymerases I, II, and III subunit RPABC3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00528300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the eukaryotic RPB8 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530507.1">
        <property type="nucleotide sequence ID" value="XM_028674123.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYQ1"/>
    <dbReference type="GeneID" id="39733816"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00528300"/>
    <dbReference type="OMA" id="YRMVIST"/>
    <dbReference type="OrthoDB" id="10249565at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005570">
        <property type="entry name" value="RPABC3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10917">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10917:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03870">
        <property type="entry name" value="RNA_pol_Rpb8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000779">
        <property type="entry name" value="RNA_pol_Rpb8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00658">
        <property type="entry name" value="RPOL8c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="145" mass="16842" checksum="3A8BAD4D86C9B401" modified="2017-02-15" version="1">MASSILFEDRFVISSVDNSKFEKVSRIKAKSTGYDAELILDVHSELFKVEEKKAIYLALQDKFLTKNDEKIWEQTENISLNNIEYIMSGRIFKFEELSSERRTVYASFGGLMMALTADKQFIGDLEIDMKIYLLTKNVDIEMTRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYT8</accession>
    <name>A0A1J1GYT8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">60S ribosomal protein L24, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00505200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530280.1">
        <property type="nucleotide sequence ID" value="XM_028673871.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYT8"/>
    <dbReference type="GeneID" id="39733585"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00505200"/>
    <dbReference type="OMA" id="QVFRRMH"/>
    <dbReference type="OrthoDB" id="1727108at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00472">
        <property type="entry name" value="Ribosomal_L24e_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.170.20:FF:000003">
        <property type="entry name" value="60S ribosomal protein L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.20">
        <property type="entry name" value="Ribosomal protein L24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038630">
        <property type="entry name" value="L24e/L24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056366">
        <property type="entry name" value="Ribosomal_eL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000988">
        <property type="entry name" value="Ribosomal_eL24-rel_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10792">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10792:SF1">
        <property type="entry name" value="RIBOSOMAL PROTEIN L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01246">
        <property type="entry name" value="Ribosomal_L24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein eL24-related N-terminal" evidence="5">
        <location>
            <begin position="9"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="114"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="116"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="162" mass="19073" checksum="909813950310ACC6" modified="2017-02-15" version="1">MASIKTTVKTEACSFSEYRIYPGRGQKYIAKDGKVYFYLSSKFASLALQKKKAAKLRWTQAWRRNNKKTKVETTQRRRYKKTIKVQKAVCGLTVEDIRNRKAYVQSIEAKNKARLAAKEKDDKKKGKDDKKKNIVHFQQKKDFNKSNRINMAKTKMHKMMKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYY8</accession>
    <name>A0A1J1GYY8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Bifunctional enzyme of folate synthesis, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PGAL8A_00525300</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(7,8-dihydropterin-6-yl)methyl diphosphate + 4-aminobenzoate = 7,8-dihydropteroate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19949"/>
            <dbReference type="ChEBI" id="CHEBI:17836"/>
            <dbReference type="ChEBI" id="CHEBI:17839"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:72950"/>
            <dbReference type="EC" id="2.5.1.15"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>6-hydroxymethyl-7,8-dihydropterin + ATP = (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11412"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:44841"/>
            <dbReference type="ChEBI" id="CHEBI:72950"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.6.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 7,8-dihydrofolate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">In the C-terminal section; belongs to the DHPS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530478.1">
        <property type="nucleotide sequence ID" value="XM_028674091.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYY8"/>
    <dbReference type="GeneID" id="39733786"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00525300"/>
    <dbReference type="OMA" id="FAKKHDQ"/>
    <dbReference type="OrthoDB" id="615426at2759"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005740">
        <property type="term" value="C:mitochondrial envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003848">
        <property type="term" value="F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004156">
        <property type="term" value="F:dihydropteroate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.560">
        <property type="entry name" value="7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="entry name" value="Dihydropteroate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045031">
        <property type="entry name" value="DHP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006390">
        <property type="entry name" value="DHP_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000550">
        <property type="entry name" value="Hppk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035907">
        <property type="entry name" value="Hppk_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01496">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20941">
        <property type="entry name" value="FOLATE SYNTHESIS PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20941:SF1">
        <property type="entry name" value="FOLIC ACID SYNTHESIS PROTEIN FOL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01288">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55083">
        <property type="entry name" value="6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="Dihydropteroate synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00793">
        <property type="entry name" value="DHPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pterin-binding" evidence="15">
        <location>
            <begin position="334"/>
            <end position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="CRG97677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="647" mass="76756" checksum="F857C03C9425D1B5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ30</accession>
    <name>A0A1J1GZ30_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GTPase-activating protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00027800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530643.1">
        <property type="nucleotide sequence ID" value="XM_028674273.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ30"/>
    <dbReference type="GeneID" id="39728801"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00027800"/>
    <dbReference type="OMA" id="CNIENEE"/>
    <dbReference type="OrthoDB" id="295078at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF9">
        <property type="entry name" value="GTPASE ACTIVATING PROTEIN AND CENTROSOME-ASSOCIATED, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="243"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="298"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="324"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="348"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="Rab-GAP TBC" evidence="3">
        <location>
            <begin position="169"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="545" mass="64999" checksum="5821AC43967C45E0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ44</accession>
    <name>A0A1J1GZ44_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00507800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530306.1">
        <property type="nucleotide sequence ID" value="XM_028673900.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ44"/>
    <dbReference type="GeneID" id="39733611"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00507800"/>
    <dbReference type="OMA" id="FTECANS"/>
    <dbReference type="OrthoDB" id="376388at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="511" mass="61444" checksum="8FCFEBCE7BEA6B53" modified="2017-02-15" version="1">MIGSDNNSEYALEICKICKENANANAVTLDKNVTSSCTCQNNIKSFLEKKKPNYKNLFHQNNLSYKSFSEKNFNQEKLKIYFKKVKQDKKFSDNEFMDKSKKRIINKNGKKGKESINFKKKENEDKKKLEEKEKNKDIKREEEKEKNKDIKKEEEKEKNKDIKKEEEEKNEEKKNQVEEIEEIEEIEEINNFEKNKQLNINEMDENNQIEEKREYDNEKIKNKFNVFHIGINKIEAIKALYRDCKNNFNKSFKEKINKLNSLMYFCNDNNFENNISVDYINDIDKINSIKKERLSRLFLYIEDINKLKQAFKVKQHNNMELEDNENTEYFYDANEDIEDFFIFDDSFSCINNDVDSIFTENENATFLKENKSNDHYLEEGKDKSDEENNMLNIFTRFSLKNYYCFDINKNLCSIYAFTPMIIKKFAEKINSYNIYRSDKVINNNEENNINFTLDCKNNDKINYYSHYTLDDGHNLDTYIQFHCDKWQENMYDIVEVNSLEFDFNCLKCNIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZP4</accession>
    <name>A0A1J1GZP4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Metabolite/drug transporter, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00038000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530742.1">
        <property type="nucleotide sequence ID" value="XM_028674383.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZP4"/>
    <dbReference type="GeneID" id="39728904"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00038000"/>
    <dbReference type="OMA" id="RLMKYPR"/>
    <dbReference type="OrthoDB" id="440553at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17331">
        <property type="entry name" value="MFS_SLC22A18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24002">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24002:SF3">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 22 MEMBER 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="156"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="186"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="242"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="279"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="306"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="331"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="364"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="391"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="442" mass="49110" checksum="7F4BFCD27D194C85" modified="2017-02-15" version="1">MEVTSSLLEKNKNLVDNTSEVLPRTRKFFVSSIGKAHLINSLYGIGYTIQIAMLPYLLISSNAGIEHNGYLLTLFSFLQFIGSIFFGRLADIWGVKKSFYLSLSSSSLMYLLLMVCESTWTYYISFLPSFFMQTFQASSMLVCLKTDDDKRTAAIGYLNLSYGLGIIFGSFLAGIMVNFLGARGNLLIALISQILALYVSKSLQEDPKLLKSDNTEEIKINNFFKSIKNEFGRVLNLFKKTYGICLLIIFGLLPILMTKFAFAPVVVDMFKLTPSHTSYLMTYAGILTIIAEGVFAPYLSSILGDIICCKFSIPLTLAGFLILSLCGAHEALVIIFMSIPLCGGALLYICGTSQMTKRVDESELGSIIGLNTSIFYAITIVAPYLAFKSYIALGLGLYWLLCAFICLVLTIYIFILDKSTFQIFKDDNDSIETMFSSIKLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZR2</accession>
    <name>A0A1J1GZR2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SET domain protein, putative</fullName>
            <ecNumber evidence="3">2.1.1.43</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SET8</name>
        <name evidence="3" type="ORF">PGAL8A_00054500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.43" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530907.1">
        <property type="nucleotide sequence ID" value="XM_028674568.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZR2"/>
    <dbReference type="GeneID" id="39729070"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00054500"/>
    <dbReference type="OrthoDB" id="5560686at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005700">
        <property type="term" value="C:polytene chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042799">
        <property type="term" value="F:histone H4K20 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051760">
        <property type="entry name" value="KMT5A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46167">
        <property type="entry name" value="N-LYSINE METHYLTRANSFERASE KMT5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46167:SF1">
        <property type="entry name" value="N-LYSINE METHYLTRANSFERASE KMT5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="1005"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="367"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="697"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="767"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="384"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="697"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="772"/>
            <end position="788"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1164" mass="139766" checksum="D7D60D009CE87887" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZR6</accession>
    <name>A0A1J1GZR6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Dynein light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00528200</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Cytoplasm</location>
            <location evidence="1 8">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the dynein light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530506.1">
        <property type="nucleotide sequence ID" value="XM_028674122.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZR6"/>
    <dbReference type="GeneID" id="39733815"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00528200"/>
    <dbReference type="OMA" id="THEKHCF"/>
    <dbReference type="OrthoDB" id="10033309at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21452">
        <property type="entry name" value="DLC-like_DYNLL1_DYNLL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.740.10:FF:000001">
        <property type="entry name" value="Dynein light chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.740.10">
        <property type="entry name" value="Protein Inhibitor Of Neuronal Nitric Oxide Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037177">
        <property type="entry name" value="DLC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019763">
        <property type="entry name" value="Dynein_light_1/2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001372">
        <property type="entry name" value="Dynein_light_chain_typ-1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11886">
        <property type="entry name" value="DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11886:SF35">
        <property type="entry name" value="DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01221">
        <property type="entry name" value="Dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01375">
        <property type="entry name" value="Dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54648">
        <property type="entry name" value="DLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01239">
        <property type="entry name" value="DYNEIN_LIGHT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5 8" id="KW-0243">Dynein</keyword>
    <keyword evidence="4 8" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6 8" id="KW-0505">Motor protein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG97705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="93" mass="10748" checksum="70A449AA950B4A20" modified="2017-02-15" version="1">MADRKANKNAVVKNVDMTEEMQIDAIDCANQALQKYNVEKDIAAHIKKEFDRKYDPTWHCVVGRNFGSYVTHETKNFIYFYIGQVAILLFKSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZW3</accession>
    <name>A0A1J1GZW3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA mismatch repair protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">MSH6</name>
        <name evidence="9" type="ORF">PGAL8A_00026700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the post-replicative DNA mismatch repair system (MMR).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530632.1">
        <property type="nucleotide sequence ID" value="XM_028674261.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZW3"/>
    <dbReference type="GeneID" id="39728790"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00026700"/>
    <dbReference type="OMA" id="TPMMAQY"/>
    <dbReference type="OrthoDB" id="10252754at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032301">
        <property type="term" value="C:MutSalpha complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1170.10:FF:000007">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001628">
        <property type="entry name" value="DNA mismatch repair protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1420.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.10">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="entry name" value="MutS, connector domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007695">
        <property type="entry name" value="DNA_mismatch_repair_MutS-lik_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017261">
        <property type="entry name" value="DNA_mismatch_repair_MutS/MSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007861">
        <property type="entry name" value="DNA_mismatch_repair_MutS_clamp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016151">
        <property type="entry name" value="DNA_mismatch_repair_MutS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF148">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MSH6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01624">
        <property type="entry name" value="MutS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05190">
        <property type="entry name" value="MutS_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037677">
        <property type="entry name" value="DNA_mis_repair_Msh6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55271">
        <property type="entry name" value="DNA repair protein MutS, domain I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53150">
        <property type="entry name" value="DNA repair protein MutS, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="8">
        <location>
            <begin position="1079"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR037677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG97832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1230" mass="143063" checksum="D2E3079090FF8334" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H006</accession>
    <name>A0A1J1H006_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Inner membrane complex protein 1h, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">IMC1h</name>
        <name evidence="2" type="ORF">PGAL8A_00535500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530578.1">
        <property type="nucleotide sequence ID" value="XM_028674202.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H006"/>
    <dbReference type="GeneID" id="39733888"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00535500"/>
    <dbReference type="OMA" id="RYMPPLM"/>
    <dbReference type="OrthoDB" id="375509at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022086">
        <property type="entry name" value="IMCp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12314">
        <property type="entry name" value="IMCp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="481"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="501" mass="57725" checksum="A3B06E0B735DF121" modified="2017-02-15" version="1">MPYQELYESNKDYENENDDINYDEIANSMLGKMDKHMYEESSVFPDYSENIDKNTSTNLNEETNATNKSTLLRNEKFSNQENGIDKHTLHATLYPRRVMTPLGPLPLPEEFKRNIPEKFVAKPIIEEREIYVSKKERKQREIEVPHVKYEHTFEKIKKQLKVSKLVPSVSQVIKEVPKEVLKPVIEEKIIEVPQGVKYVEVPVEVPCLYPPKIIPKVVTQYVERIVETIKPVVQEKIIEVPQTVIKQVPKIKTVEVPYYVPRYVEKIVEVPFKPNGEMPQLGTHSPFSISESLPPLKPTHFLNNHQNPYDQFNMHHSMYPQMNDYNKSFEQNIMNSTSPIIPNLSMPPTILKSMNSKESFSNTPINFPMNSSSILNSNGDCINQENLYSQIENLPYKHKLPEGLQWQYSDGVMNKPLMNNRNMPPLVVTCPPEIGRVTCARKDIQPDILTKTGVYEFDGFKKKGTSQSLFPPLAHHSRVPFLPPPAAPGTPDVRTIENNRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H078</accession>
    <name>A0A1J1H078_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00426400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529488.1">
        <property type="nucleotide sequence ID" value="XM_028672991.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H078"/>
    <dbReference type="GeneID" id="39732796"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00426400"/>
    <dbReference type="OrthoDB" id="66881at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="41"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1060" mass="127425" checksum="72841B734552E337" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H094</accession>
    <name>A0A1J1H094_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SUMO-conjugating enzyme UBC9</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Ubiquitin carrier protein 9</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00428000</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529504.1">
        <property type="nucleotide sequence ID" value="XM_028673008.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H094"/>
    <dbReference type="GeneID" id="39732812"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00428000"/>
    <dbReference type="OMA" id="TWECGIP"/>
    <dbReference type="OrthoDB" id="6600758at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019787">
        <property type="term" value="F:ubiquitin-like protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd23798">
        <property type="entry name" value="UBCc_UBE2I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000035">
        <property type="entry name" value="SUMO-conjugating enzyme ubc9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 11" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="12">
        <location>
            <begin position="3"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="10">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG96700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="159" mass="18204" checksum="7A31932EBDCDF327" modified="2017-02-15" version="1">MSIAKKRLAQERAEWRKDHPAGFSAKYSPMSDGKGLDIMKWICKIPGKKGGLWEGGEYPLTMEFTEDYPSKPPKCKFTTVLFHPNIYPSGTVCLSILNEDEDWKPSITIKQILLGIQDLLDNPNPNSPAQAEPFLLYQQDRESYEKKVKKQALEFRPKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0B6</accession>
    <name>A0A1J1H0B6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DnaJ protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00430400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529528.1">
        <property type="nucleotide sequence ID" value="XM_028673035.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0B6"/>
    <dbReference type="GeneID" id="39732836"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00430400"/>
    <dbReference type="OrthoDB" id="338088at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="642" mass="75214" checksum="90B630D334633206" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0N8</accession>
    <name>A0A1J1H0N8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00044400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530810.1">
        <property type="nucleotide sequence ID" value="XM_028674460.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728969"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00044400"/>
    <dbReference type="OMA" id="FITHTNN"/>
    <dbReference type="OrthoDB" id="384755at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="50"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="262"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1595"/>
            <end position="1624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1821"/>
            <end position="1878"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1895"/>
            <end position="1919"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2238"/>
            <end position="2285"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="593"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1952"/>
            <end position="2000"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="284"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="306"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1821"/>
            <end position="1839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1846"/>
            <end position="1865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2238"/>
            <end position="2247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2251"/>
            <end position="2268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="2269"/>
            <end position="2285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG98013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2285" mass="269782" checksum="5C111A2ADF4DB3AE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0Q4</accession>
    <name>A0A1J1H0Q4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">ATP synthase subunit C, putative</fullName>
            <ecNumber evidence="13">3.6.3.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00046000</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the ATPase C chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.14" evidence="13"/>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530826.1">
        <property type="nucleotide sequence ID" value="XM_028674478.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0Q4"/>
    <dbReference type="GeneID" id="39728985"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00046000"/>
    <dbReference type="OMA" id="NSSLAKX"/>
    <dbReference type="OrthoDB" id="438052at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033177">
        <property type="term" value="C:proton-transporting two-sector ATPase complex, proton-transporting domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015078">
        <property type="term" value="F:proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015986">
        <property type="term" value="P:proton motive force-driven ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18182">
        <property type="entry name" value="ATP-synt_Fo_c_ATP5G3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.20.10">
        <property type="entry name" value="F1F0 ATP synthase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000454">
        <property type="entry name" value="ATP_synth_F0_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020537">
        <property type="entry name" value="ATP_synth_F0_csu_DDCD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038662">
        <property type="entry name" value="ATP_synth_F0_csu_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10031">
        <property type="entry name" value="ATP SYNTHASE LIPID-BINDING PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10031:SF0">
        <property type="entry name" value="ATPASE PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00124">
        <property type="entry name" value="ATPASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="F1F0 ATP synthase subunit C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00605">
        <property type="entry name" value="ATPASE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0138">CF(0)</keyword>
    <keyword evidence="6 11" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="59"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="12">
        <location>
            <begin position="22"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="13">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG98029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="87" mass="9165" checksum="73D5EF72831AA73F" modified="2017-02-15" version="1" fragment="single">KDEKNIINHQLGVRHDSGIASLSAAIALISVGGVAQGIGNLFSALVLGTSRNPSIKDELFTYTLIGMGFLEFLGIICVLMSAVLLYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0R4</accession>
    <name>A0A1J1H0R4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00059000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530952.1">
        <property type="nucleotide sequence ID" value="XM_028674617.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0R4"/>
    <dbReference type="GeneID" id="39729115"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00059000"/>
    <dbReference type="OrthoDB" id="448686at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="228"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="462" mass="56491" checksum="0917245DEC680511" modified="2017-02-15" version="1">MNILKGQDKLFFFKNVKFFTFYKKNNVLLQNKLRLKDNNKHFLRLLRGRNFFISRKNENNVGNNMIKEDDNSQNENKNMEFINDTIKEECEDKNNIKDKIPYEDEEEDDDKYIKSFYEIYDDNNDTYDCPKELLRFIKKEFMNIKIKIKCSSPRNLKKNDVKNIINDMFEESENILNDNLTEKKKNEESNYDIYYLNSSFKEFNYPDKNVMWPNPLIYNHRLQPFVLKKKKNELNENFELDKKNIEINKKRLENLWRYSSSYGVDWNTLDELYLNFKKHKTEHLNDWENNKNKIMLYASKVCKRKLIKSRKQLLDKLNINYSSNIYANYDENEQLHETNLDDDQTEYNLLLPRSIFRRWIRTLYFYWKDRYMHYYNNTLCDYLKGEIVDMQLLREHNERNLNLSNKKMLNQHSFSLKPVKGSNLYITRYIKKKKINVKYDNDNEYDLTGIGEHIYNNAQKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1B3</accession>
    <name>A0A1J1H1B3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">PRP22</name>
        <name evidence="14" type="ORF">PGAL8A_00489400</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 16">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530117.1">
        <property type="nucleotide sequence ID" value="XM_028673690.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733427"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00489400"/>
    <dbReference type="OMA" id="LAPNFYK"/>
    <dbReference type="OrthoDB" id="10253254at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000390">
        <property type="term" value="P:spliceosomal complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05684">
        <property type="entry name" value="S1_DHX8_helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1080:FF:000001">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000007">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000191">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049621">
        <property type="entry name" value="S1_DHX8_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF85">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 14" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="11">
        <location>
            <begin position="328"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="638"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="13">
        <location>
            <begin position="823"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="126"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="127"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="142"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="284"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="294"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG97315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1287" mass="148765" checksum="8C82272982134B51" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1C6</accession>
    <name>A0A1J1H1C6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00469000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529912.1">
        <property type="nucleotide sequence ID" value="XM_028673462.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1C6"/>
    <dbReference type="GeneID" id="39733223"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00469000"/>
    <dbReference type="OMA" id="VWRSATW"/>
    <dbReference type="OrthoDB" id="435607at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="137" mass="16493" checksum="1FA9991D6AA47803" modified="2017-02-15" version="1">MSFLKFIYLIVMPLGIFLLLSCLLKIKFLVKFSYSFCRKKIGDTSVRIVSLILILNFIIFISESYKLRYNVKKMYNPNELIAGISSDYLKLYKWRHERNWWIGLSNLCIWIILWRSTGIINHYVNYLEQRKNQVKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1R3</accession>
    <name>A0A1J1H1R3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00504800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530276.1">
        <property type="nucleotide sequence ID" value="XM_028673867.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1R3"/>
    <dbReference type="GeneID" id="39733581"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00504800"/>
    <dbReference type="OMA" id="CERINEN"/>
    <dbReference type="OrthoDB" id="2163284at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="358"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="35"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="358"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="381"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="518" mass="60717" checksum="876E10E67FA72454" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1W7</accession>
    <name>A0A1J1H1W7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00489700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530120.1">
        <property type="nucleotide sequence ID" value="XM_028673693.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1W7"/>
    <dbReference type="GeneID" id="39733430"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00489700"/>
    <dbReference type="OrthoDB" id="328505at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="225" mass="26804" checksum="EBC8DFA634EB614B" modified="2017-02-15" version="1">MEKRGILSTDDENTKSTKESLKRNEKQIQFLVYVLKKYIKKDEELKNRAYYFFPSDDALDKILFNLCKFIPKDKNILEINKKLNIFDSDSLFECANSERDSWNNQNTMFDDISLDEHNNKKYKTSSNFNLKDRKTNKVCVEWQGFVNEANGYAAIKIIVPFVYQEYYTYANRLVYFLFQKTKCLEVEDFLSHHKFINKIVPLYMTCKNKLCVKLSHIDASNDLYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3G8</accession>
    <name>A0A1J1H3G8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">MORN repeat protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00032500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530687.1">
        <property type="nucleotide sequence ID" value="XM_028674323.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3G8"/>
    <dbReference type="GeneID" id="39728848"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00032500"/>
    <dbReference type="OMA" id="FCIEGKW"/>
    <dbReference type="OrthoDB" id="296831at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018307">
        <property type="entry name" value="ABL9/DENND6_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23084:SF263">
        <property type="entry name" value="MORN REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23084">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09794">
        <property type="entry name" value="Avl9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="AVL9/DENND6" evidence="3">
        <location>
            <begin position="219"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="530"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1254" mass="149599" checksum="7ECA059CD861A97F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2012-07-11" modified="2026-01-28" version="47" xmlns="https://uniprot.org/uniprot">
    <accession>I2FKC2</accession>
    <name>I2FKC2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 17">Phosphoglycerate kinase</fullName>
            <ecNumber evidence="6 17">2.7.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">PGK</name>
        <name evidence="20" type="ORF">PGAL8A_00435400</name>
    </gene>
    <organism evidence="19">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2012" name="Gene" volume="502" first="36" last="39">
            <title>Age of the last common ancestor of extant Plasmodium parasite lineages.</title>
            <authorList>
                <person name="Hayakawa T."/>
                <person name="Tachibana S."/>
                <person name="Hikosaka K."/>
                <person name="Arisue N."/>
                <person name="Matsui A."/>
                <person name="Horii T."/>
                <person name="Tanabe K."/>
            </authorList>
            <dbReference type="PubMed" id="22555021"/>
            <dbReference type="DOI" id="10.1016/j.gene.2012.04.037"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="20 21" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 17">
            <text>(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:14801"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 17">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 18">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 17">Belongs to the phosphoglycerate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.3" evidence="6 17"/>
    <dbReference type="EMBL" id="AB571131">
        <property type="protein sequence ID" value="BAM15607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529575.1">
        <property type="nucleotide sequence ID" value="XM_028673086.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="I2FKC2"/>
    <dbReference type="GeneID" id="39732886"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00435400"/>
    <dbReference type="OMA" id="GPETNKK"/>
    <dbReference type="OrthoDB" id="275353at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004618">
        <property type="term" value="F:phosphoglycerate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00318">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1260:FF:000003">
        <property type="entry name" value="Phosphoglycerate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1260:FF:000017">
        <property type="entry name" value="Phosphoglycerate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1260:FF:000019">
        <property type="entry name" value="Phosphoglycerate kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1260">
        <property type="entry name" value="Phosphoglycerate kinase, N-terminal domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00145">
        <property type="entry name" value="Phosphoglyc_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001576">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015911">
        <property type="entry name" value="Phosphoglycerate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015824">
        <property type="entry name" value="Phosphoglycerate_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036043">
        <property type="entry name" value="Phosphoglycerate_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11406">
        <property type="entry name" value="PHOSPHOGLYCERATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11406:SF0">
        <property type="entry name" value="PHOSPHOGLYCERATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00162">
        <property type="entry name" value="PGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000724">
        <property type="entry name" value="Pgk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00477">
        <property type="entry name" value="PHGLYCKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53748">
        <property type="entry name" value="Phosphoglycerate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00111">
        <property type="entry name" value="PGLYCERATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="11 17 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 17 20" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="24"/>
            <end position="26"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>(2R)-3-phosphoglycerate</name>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="63"/>
            <end position="66"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>(2R)-3-phosphoglycerate</name>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>(2R)-3-phosphoglycerate</name>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="343"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <begin position="372"/>
            <end position="375"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00016471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000724-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR000724-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU000532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU000696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="BAM15607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="CRG96772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="416" mass="46057" checksum="1363E51F99C4FE4B" modified="2012-07-11" version="1">MLGNKLSLTDIKDIKNKKVLVRVDFNVPIDNGIIKDNTRITATLPTIKYLKKEGASKIILISHCGRPDGLRNLKYTLKPVAENLKSLLGEEVLFLDECVGKEVEKQINEAKDNSIILLENLRFHIEEEGKGIDENGKKIKAKTEDIEKFQNDLTKLGDIFINDAFGTAHRPHSSMVGIKLNVKASGFLMKKELEYFSKALENPQRPFLAILGGAKVSDKIQLIRNLLDKVNRMIIGGGMAYTFKHVLNKMKIGSSLFDEEGSKIVEDIMKKAKEKNVQIYLPVDFKIADKFSNDANTKIVTEEEGIEDNWMGMDAGNKTIQNYRDVILTSKTIIWNGPQGVFEMPNFAKGSIECLNLVVEATKNGSISIVGGGDTASLVEQQKKKNEISHVSTGGGASLELLEGKQLPGVQALSNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL11</accession>
    <name>A0A1J1GL11_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">T-cell immunomodulatory protein TIP C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00076300</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TIP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525879.1">
        <property type="nucleotide sequence ID" value="XM_028670011.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL11"/>
    <dbReference type="GeneID" id="39729288"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00076300"/>
    <dbReference type="OMA" id="PGDWIPW"/>
    <dbReference type="OrthoDB" id="10022113at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="entry name" value="Integrin alpha, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057089">
        <property type="entry name" value="C2_TIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024881">
        <property type="entry name" value="Tip"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13412:SF0">
        <property type="entry name" value="T-CELL IMMUNOMODULATORY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13412">
        <property type="entry name" value="T-CELL IMMUNOMODULATORY PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23122">
        <property type="entry name" value="C2_ITFG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="Integrin alpha N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="624"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="662"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="domain" description="T-cell immunomodulatory protein TIP C2" evidence="8">
        <location>
            <begin position="558"/>
            <end position="654"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF23122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="705" mass="81453" checksum="7938C921BE6A2FB0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL16</accession>
    <name>A0A1J1GL16_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Adenylyl cyclase beta, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00078800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525908.1">
        <property type="nucleotide sequence ID" value="XM_028670333.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729313"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00078800"/>
    <dbReference type="OrthoDB" id="194468at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47455">
        <property type="entry name" value="ADENYLYL CYCLASE BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47455:SF1">
        <property type="entry name" value="GUANYLATE CYCLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Guanylate cyclase" evidence="1">
        <location>
            <begin position="112"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="1">
        <location>
            <begin position="375"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1762" mass="209264" checksum="DF23549B29BBAE96" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL78</accession>
    <name>A0A1J1GL78_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutamate-rich WD repeat-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00086200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525980.1">
        <property type="nucleotide sequence ID" value="XM_028671133.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL78"/>
    <dbReference type="GeneID" id="39729386"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00086200"/>
    <dbReference type="OMA" id="NVFAASW"/>
    <dbReference type="OrthoDB" id="2161379at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051972">
        <property type="entry name" value="Glutamate-rich_WD_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022052">
        <property type="entry name" value="Histone-bd_RBBP4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45903">
        <property type="entry name" value="GLUTAMATE-RICH WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45903:SF1">
        <property type="entry name" value="GLUTAMATE-RICH WD REPEAT-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12265">
        <property type="entry name" value="CAF1C_H4-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Histone-binding protein RBBP4-like N-terminal" evidence="7">
        <location>
            <begin position="3"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="304"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="348"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00040876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="439" mass="50959" checksum="496C357487CE1F20" modified="2017-02-15" version="1">MNEDLEIDENAYDMFFSPLTPWPCLSFDFILPNSSCYFSEKSKKETNSELVNNIPLKYPIDICCVGGTQANKSELNNIYVIKWSNLNKLKNCETENSSDDSEYDDEEENDISLNEHDNMEKKKKVKNEFLDEKSNIICKSIKHEYGCINKIKVSKKINSLVAAWCEDSNVYIYELSDEIKNLDDRGYNEEIEKKPLHVFEKHSKEGFSLDWNNIYAAKLLTGDNDGNLYLWLPHNSDKWNYEYWDFKKYADNKINKKYSIEDIEWCKKGNGLGNVFCICSSDKSIRILDIRNLNNNNNTNINIENAHENDVNVISWNENSEFLLASGGDDNLIKIWDIRNTRNSVAQLNFHKQPITSVCWDSKDTYVLLASSLDNSITIWDLSVESEALEYSHSKYPDQLLFEHLNQNFITEAKFHPYFSGVVVSTSCDNFNIFKPCNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL90</accession>
    <name>A0A1J1GL90_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Carbon catabolite repressor protein 4, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CCR4</name>
        <name evidence="4" type="ORF">PGAL8A_00066900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG92965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525787.1">
        <property type="nucleotide sequence ID" value="XM_028670088.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729194"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00066900"/>
    <dbReference type="OrthoDB" id="428734at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050410">
        <property type="entry name" value="CCR4/nocturin_mRNA_transcr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121">
        <property type="entry name" value="CARBON CATABOLITE REPRESSOR PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121:SF34">
        <property type="entry name" value="PROTEIN ANGEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="3">
        <location>
            <begin position="1557"/>
            <end position="1912"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="192"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="383"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1149"/>
            <end position="1171"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1416"/>
            <end position="1443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="192"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="210"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="278"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="334"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="383"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="398"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1149"/>
            <end position="1169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG92965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1924" mass="225070" checksum="A6C9B95860C7FC3D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLF2</accession>
    <name>A0A1J1GLF2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00089700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526015.1">
        <property type="nucleotide sequence ID" value="XM_028671521.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLF2"/>
    <dbReference type="GeneID" id="39729421"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00089700"/>
    <dbReference type="OMA" id="NERTEEC"/>
    <dbReference type="OrthoDB" id="10067079at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004860">
        <property type="term" value="F:protein kinase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009548">
        <property type="entry name" value="Prkrip1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13507">
        <property type="entry name" value="PRKR-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13507:SF0">
        <property type="entry name" value="PRKR-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06658">
        <property type="entry name" value="DUF1168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="206" mass="24547" checksum="8D908A1C6506DC31" modified="2017-02-15" version="1">MDLKVLDDEIMLSDGRIIKIPIKNEENNKDKEKGKIKIEKIPNVWGSSAGAGSDYFDIYRKQRNEENERIELIEKKWKEYTENQIFQNKRKAKIEYIEKKRLKKKNKRLIKKNKLKQQQNNKKFNKNETQISHPSLKQNEKNKELNDDNVKTNEDHVKNNKNYNGNENNILDEEKYIEKEVNEDNGAIIPPIDTNNFLVVKEDELF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM61</accession>
    <name>A0A1J1GM61_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Translation initiation factor eIF2B subunit alpha</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">eIF2B GDP-GTP exchange factor subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00121700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">Component of the translation initiation factor 2B (eIF2B) complex which is a heterodecamer of two sets of five different subunits: alpha, beta, gamma, delta and epsilon. Subunits alpha, beta and delta comprise a regulatory subcomplex and subunits epsilon and gamma comprise a catalytic subcomplex. Within the complex, the hexameric regulatory complex resides at the center, with the two heterodimeric catalytic subcomplexes bound on opposite sides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the eIF-2B alpha/beta/delta subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526332.1">
        <property type="nucleotide sequence ID" value="XM_028674730.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM61"/>
    <dbReference type="GeneID" id="39729742"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00121700"/>
    <dbReference type="OMA" id="GDWESCK"/>
    <dbReference type="OrthoDB" id="10249309at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005851">
        <property type="term" value="C:eukaryotic translation initiation factor 2B complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="entry name" value="Translation initiation factor eif-2b, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1070">
        <property type="entry name" value="Translation initiation factor eIF-2B, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051501">
        <property type="entry name" value="eIF2B_alpha/beta/delta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042528">
        <property type="entry name" value="elF-2B_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45860">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45860:SF1">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 10" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG93510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="341" mass="40007" checksum="124D1AB19EF93A33" modified="2017-02-15" version="1">MDYFNYVKRDLLEEHEVVRSFKKHYFEEENEMHIAAIKSLADVIKNNISETNFELFINLNEAKDILNNYIKNNDVQNNIISVPHSKRMTIYTIVSSCDIYHHFVVKKYTHNENYFNNLKNTLANNANEFSKNLEKSLDIIGNTSNIMFINRKTTVLTHSNSKCVKNLLLNVVKNENKQVFVYFTSLENSSINYSEKDKKFDDIFIEDLRKENIIVTKINLQSVKNIFNIIDFVVIGTELVIDSGGIISKKGIRLLSQLCSLNKKPFYVVCEAYKFLKIDKIKYAKDFYDYCTQNICNENNYLYEYVPHHLITLFYTDIGIFSPSVISYELSKLYINDAFQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMH6</accession>
    <name>A0A1J1GMH6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">DNA repair protein RAD50, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">RAD50</name>
        <name evidence="12" type="ORF">PGAL8A_00134300</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SMC family. RAD50 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526460.1">
        <property type="nucleotide sequence ID" value="XM_028674872.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729868"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00134300"/>
    <dbReference type="OMA" id="ILCHHEE"/>
    <dbReference type="OrthoDB" id="18797at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000794">
        <property type="term" value="C:condensed nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030870">
        <property type="term" value="C:Mre11 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003691">
        <property type="term" value="F:double-stranded telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051880">
        <property type="term" value="F:G-quadruplex DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043047">
        <property type="term" value="F:single-stranded telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070192">
        <property type="term" value="P:chromosome organization involved in meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000722">
        <property type="term" value="P:telomere maintenance via recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007004">
        <property type="term" value="P:telomere maintenance via telomerase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001805">
        <property type="entry name" value="Similar to DNA repair protein rad50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18867:SF12">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18867">
        <property type="entry name" value="RAD50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Rad50/SbcC-type AAA" evidence="11">
        <location>
            <begin position="6"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="218"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="284"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="510"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="956"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="1391"/>
            <end position="1456"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="1535"/>
            <end position="1573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG93638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1801" mass="216232" checksum="5F4D72AE9B51826E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GML7</accession>
    <name>A0A1J1GML7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Palmitoyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">DHHC2</name>
        <name evidence="9" type="ORF">PGAL8A_00138400</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526500.1">
        <property type="nucleotide sequence ID" value="XM_028674917.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GML7"/>
    <dbReference type="GeneID" id="39729908"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00138400"/>
    <dbReference type="OMA" id="VAVQTFH"/>
    <dbReference type="OrthoDB" id="9909019at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12246">
        <property type="entry name" value="PALMITOYLTRANSFERASE ZDHHC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="8">
        <location>
            <begin position="95"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="284" mass="33497" checksum="58E678DAE2DA22B9" modified="2017-02-15" version="1">MRPKYIQDSQVQKEKKRGGSFFIFIVFFILSFIYIGYTGIVLRSWFIPYRSGSLTIAIVFHFFFFLFLLSFIKCASTDPGKVPRNWGFYVGDDVKRRRYCKICNIWKPDRTHHCSACNRCVLNMDHHCPWINNCVGFFNRRFFMQLLFYGLICLFIVASQTFHYIFIDNTYAYSDDEFHEKSSFIAFEYTYASIVLFLTFVLIFALVPFTKFHLKLISKNSTTIENMDTYNQEYNIYNIGCENNAKQVFGNNILCWLCPFQCVSNRPAGDGVRWRVSVSHDDNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN84</accession>
    <name>A0A1J1GN84_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Signal recognition particle subunit SRP68</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00150400</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SRP68 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526617.1">
        <property type="nucleotide sequence ID" value="XM_028675047.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN84"/>
    <dbReference type="GeneID" id="39730028"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00150400"/>
    <dbReference type="OMA" id="ERICLYN"/>
    <dbReference type="OrthoDB" id="10255118at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030942">
        <property type="term" value="F:endoplasmic reticulum signal peptide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005047">
        <property type="term" value="F:signal recognition particle binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3450.40">
        <property type="entry name" value="Signal recognition particle, SRP68 subunit, RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026258">
        <property type="entry name" value="SRP68"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038253">
        <property type="entry name" value="SRP68_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12860">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 68 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12860:SF0">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE SUBUNIT SRP68"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16969">
        <property type="entry name" value="SRP68"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0733">Signal recognition particle</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG93795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="682" mass="81295" checksum="BDAB65B1B9697BA1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNI5</accession>
    <name>A0A1J1GNI5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00172500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526839.1">
        <property type="nucleotide sequence ID" value="XM_028670048.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNI5"/>
    <dbReference type="GeneID" id="39730252"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00172500"/>
    <dbReference type="OMA" id="MGQVNDY"/>
    <dbReference type="OrthoDB" id="381817at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="87" mass="9911" checksum="98018C92DAD92F45" modified="2017-02-15" version="1">MNITNDSDNINENNNEKKDYLVKSTTFLNNEKIFECSSKIASADKIKINDESVEILMSNNNLTDHIISVMGHVNTFFTKKINDKKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNN4</accession>
    <name>A0A1J1GNN4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00379300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526910.1">
        <property type="nucleotide sequence ID" value="XM_028670127.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNN4"/>
    <dbReference type="GeneID" id="39732323"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00379300"/>
    <dbReference type="OMA" id="TGILFHT"/>
    <dbReference type="OrthoDB" id="437441at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="94" mass="10728" checksum="99B402CD5F4B9DF9" modified="2017-02-15" version="1">MILRRSSMRLFSSEFKSLPKPPAGTGVVFHGNIQQVKYAIDFSSYIFIIFSGFMGAISGNFFYKKFILRKNPPNPLRDPLDLPPEKHPHTPDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNW9</accession>
    <name>A0A1J1GNW9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00385800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526975.1">
        <property type="nucleotide sequence ID" value="XM_028670198.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNW9"/>
    <dbReference type="GeneID" id="39732388"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00385800"/>
    <dbReference type="OMA" id="YTIRKFP"/>
    <dbReference type="OrthoDB" id="60843at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039123">
        <property type="entry name" value="PPTC7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320:SF1">
        <property type="entry name" value="PROTEIN PHOSPHATASE PTC7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012453006" description="Protein phosphatase" evidence="2">
        <location>
            <begin position="19"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="PPM-type phosphatase" evidence="3">
        <location>
            <begin position="163"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="397" mass="46595" checksum="11AC289CF59508A5" modified="2017-02-15" version="1">MIFIFLFFLIIFLSNMSTYKKETSYNVYSIVADKFKRKMSYLLKKDDYYFYRYNFNTFSKELEKQLKKKSKTKNELGMLNNVLDKLSFLHSQNKNKNYNKKCDKKFNKCSNELKVVVKPPHLFLKKNLPFNFFNFANLIYIKHKLKRNILFSLNKKSYSSINKHSFSTNYKIIKHPDKKESEDCCLNGQDFMAIADGVGSWIKYGINPRKYPEKFLQLLHKKINENINMKIEDALNYAYLNTDIEGSATICLIIFNNNNTVSTAVIGDSQFMIIRNNNIIYKSKPQQYEFNFPYQLGSNSLSKPKDAEIAHIEVQKNDIIVAGTDGLWDNLYDNQILNIVKKNEFSMLSEKIANEAFNYSKMKRWMSPYIKNYNKIFNCHKTGGKMDDITVSCALVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP14</accession>
    <name>A0A1J1GP14_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00393500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527052.1">
        <property type="nucleotide sequence ID" value="XM_028670284.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP14"/>
    <dbReference type="GeneID" id="39732465"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00393500"/>
    <dbReference type="OrthoDB" id="371744at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="12"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="170" mass="20727" checksum="ABCAE2DC6F90FEA9" modified="2017-02-15" version="1">MKSVISKNKKKDDEQLMKAKELKEKIESMKNDLVSKTIIMKSLKEQRENKLENIKKLEIENKTSYENFKNEYEQILNQYKNIEKEIYEMLNDLKMLSERSYIIEEKKKDLHHQIEEVECEIIKHSHMINDILIKIKEIFKKTHIQYQYEEDLKPLLIRLQDINKKDDKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP28</accession>
    <name>A0A1J1GP28_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00394500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527062.1">
        <property type="nucleotide sequence ID" value="XM_028670295.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732475"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00394500"/>
    <dbReference type="OrthoDB" id="10261640at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="477"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1117"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1201"/>
            <end position="1222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1980"/>
            <end position="2112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1119"/>
            <end position="1158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1206"/>
            <end position="1218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1981"/>
            <end position="2001"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2002"/>
            <end position="2014"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="2015"/>
            <end position="2055"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2067"/>
            <end position="2084"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2091"/>
            <end position="2112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2112" mass="251308" checksum="DEABEB8633D7E672" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP95</accession>
    <name>A0A1J1GP95_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">E3 ubiquitin-protein ligase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00399400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527111.1">
        <property type="nucleotide sequence ID" value="XM_028670350.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP95"/>
    <dbReference type="GeneID" id="39732524"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00399400"/>
    <dbReference type="OMA" id="EIKMLCR"/>
    <dbReference type="OrthoDB" id="1711136at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045194">
        <property type="entry name" value="MGRN1/RNF157-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22996">
        <property type="entry name" value="MAHOGUNIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22996:SF0">
        <property type="entry name" value="RE60872P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="410"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="272"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="467" mass="55222" checksum="D86FD55FFD80CFD3" modified="2017-02-15" version="1">MNIIDEYDLDMYKNLVMTNNCKDEELLCIFNTSSFLNTMCFFLFFIMFLWFLSIVSRFYASYNIMKYLKNRKAIYMKNMSRYINEVKMLCRSHVNDIIRIKKKITPKSVDKINLNISVKNNIQLYKNYLSSSCNDLNQLYKYSISFTFSSKNSLYIRLFWGVLLKEVNEIIHNRMELNKKSINGPNTVICIDNFKNFFKDGFSKSIPNKQISDATTLLLDKKKNDYYLDSKDDEMIDFNTCFYKSPKSFFSNGNNVTYTMPYDENFCVTEILNEIEVEKTNVIKQKEKEENENKKKKLKKNKIDVQENTIMSNEDNIRIPLIIVLNDIPSDDQFNLNKASKKPKKNDNCNTLIVLVDFKKIKDKYKPFIIKDICVLNQNVSSQKSKKKCNIVQFIDILDIYGHEEHDKECLICMTSYKDTLLMPCRHSSFCYDCMKSLRQEKCPICRCLFTSFIKFPLKNIDKNEIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPA7</accession>
    <name>A0A1J1GPA7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00383600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526953.1">
        <property type="nucleotide sequence ID" value="XM_028670174.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPA7"/>
    <dbReference type="GeneID" id="39732366"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00383600"/>
    <dbReference type="OMA" id="CYDNNDD"/>
    <dbReference type="OrthoDB" id="385818at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="109" mass="12950" checksum="DBB133C4960C6A9E" modified="2017-02-15" version="1">MVLKEKKNKKYSSKYNKKSKGNNSMEKDTKKKNTSKNEFYDENDLPYYDSNDDFLIKNNELFYDIFKYDDELNQVKKQNIEPSSIIKEKEKHSDFVITSIAFNIPVGMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPK7</accession>
    <name>A0A1J1GPK7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">CGI-141 protein homolog, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00092700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the GOT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526045.1">
        <property type="nucleotide sequence ID" value="XM_028671854.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPK7"/>
    <dbReference type="GeneID" id="39729451"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00092700"/>
    <dbReference type="OMA" id="LMGWPIV"/>
    <dbReference type="OrthoDB" id="204784at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045176">
        <property type="entry name" value="Got1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007305">
        <property type="entry name" value="Vesicle_transpt_Got1/SFT2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21493">
        <property type="entry name" value="CGI-141-RELATED/LIPASE CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21493:SF9">
        <property type="entry name" value="GOLGI TRANSPORT PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04178">
        <property type="entry name" value="Got1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="66"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="136" mass="15736" checksum="C02E86CA59019647" modified="2017-02-15" version="1">MLDQNKTVGLLLFLLGIVFGFIGIALFFDKFFLCISNILFLLGLYFLVGIRKILRFFMNRKKIAGSACFIIGLLLIIFSRTFIGFLFQAYGIYKLFFSFLPNIVNFIKYSPFSFLLELPGIKQMSNYIVNNKRLPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPX6</accession>
    <name>A0A1J1GPX6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00196200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527382.1">
        <property type="nucleotide sequence ID" value="XM_028670651.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730489"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00196200"/>
    <dbReference type="OMA" id="FRSIWMS"/>
    <dbReference type="OrthoDB" id="381991at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1389" mass="167952" checksum="E77961CF7BB0A057" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ51</accession>
    <name>A0A1J1GQ51_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 subunit G</fullName>
            <shortName evidence="5">eIF3g</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 RNA-binding subunit</fullName>
            <shortName evidence="5">eIF-3 RNA-binding subunit</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Eukaryotic translation initiation factor 3 subunit 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00086600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the eIF-3 subunit G family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525984.1">
        <property type="nucleotide sequence ID" value="XM_028671177.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ51"/>
    <dbReference type="GeneID" id="39729390"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00086600"/>
    <dbReference type="OrthoDB" id="1749473at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12408">
        <property type="entry name" value="RRM_eIF3G_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03006">
        <property type="entry name" value="eIF3g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017334">
        <property type="entry name" value="eIF3_g"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024675">
        <property type="entry name" value="eIF3g_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034240">
        <property type="entry name" value="eIF3G_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10352">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12353">
        <property type="entry name" value="eIF3g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037949">
        <property type="entry name" value="Transl_init_eIF-3_RNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 8" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="187"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="268" mass="31448" checksum="5160BE058CFA2250" modified="2017-02-15" version="1">MIQTEKKWADIDVDDDESLIDNENKKKWEDIDADDDLENNKKLSYFTNYENGIKVVTKYSENLKKQTVKVTKKIKEVVIKKKLNKEINNRLNLKKFNVDCHNSVTVEPTDVINIEVPKNNPLDFLKDTEYDYLFAEQTNKTTKDLKNRFKILKDEEVDEVKAEDTSKNATRRDGLYYRSHDTQNKECTVRVTNLSEDVNENELSNLFGRVGNIVRMFLAKHKETQNSKGFAFITYSKREEAKRAIEKLNRHGFENLLLSVEWAKPSNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ83</accession>
    <name>A0A1J1GQ83_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00209000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527508.1">
        <property type="nucleotide sequence ID" value="XM_028670791.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ83"/>
    <dbReference type="GeneID" id="39730617"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00209000"/>
    <dbReference type="OMA" id="GLECMAT"/>
    <dbReference type="OrthoDB" id="341976at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="168" mass="19758" checksum="67297616EC853C4C" modified="2017-02-15" version="1">MDDVIIEEKDNNIKKDQLESGKSDNKNLLNEIHETSVPKNLVCLICYDDIDENNYIEYKTDEFSKWYPSLFCLNCTNILIKTQYHQYINNVQKSECLREQTNLLQMGPPINVKDKNGFPFSDGKEIYSLWFFSDKQIHSAKLEGSLVGEERIKVWNELKKFLIHDKTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQC7</accession>
    <name>A0A1J1GQC7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mitochondrial ribosomal protein S11, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00213800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527556.1">
        <property type="nucleotide sequence ID" value="XM_028670844.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQC7"/>
    <dbReference type="GeneID" id="39730665"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00213800"/>
    <dbReference type="OMA" id="ARKCKRL"/>
    <dbReference type="OrthoDB" id="415302at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.80:FF:000008">
        <property type="entry name" value="Mitochondrial ribosomal protein S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.80">
        <property type="entry name" value="Ribosomal protein S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036967">
        <property type="entry name" value="Ribosomal_uS11_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53137">
        <property type="entry name" value="Translational machinery components"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="24"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="233" mass="27321" checksum="D2F66254F27003C5" modified="2017-02-15" version="1">MFRVISVLNKNFFLRNNSRFCLCLSALKENINSFKINFINLNKKTHRNYTTLSQEAVEAITNLKETVKKQDRKKKNITRETLKNCQGHKRRFKLFGDREEFHNVDRDKNNLIIEPTDSFRAVITTSKNNVHIQVVNKSKNYKTIFGSFAGNVGFTKSLQQSERCAYRIGENIAKKCRRLGIFSIDVKFRRIMRVETILQAMYANNLNITHIIHEPRLPKCGLNASKPRKRRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQG4</accession>
    <name>A0A1J1GQG4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00192800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000029">
        <property type="protein sequence ID" value="CRG94530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527345.1">
        <property type="nucleotide sequence ID" value="XM_028670609.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQG4"/>
    <dbReference type="GeneID" id="39730453"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00192800"/>
    <dbReference type="OrthoDB" id="373391at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="140" mass="16782" checksum="A4B732BE495D6C0B" modified="2017-02-15" version="1">MALTTDYSKLSDIVYEVLDSPSIYNKEKYFKQKQNDNYYDIKKFMCIGSTINDNANFEELDKILKEGNKKCQNTLTESYKLQGYKYSISNNNDNIKFTKLFFDNYANLFYCMHLHNDDKKCNPLFKHFYETINYDKINKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQH8</accession>
    <name>A0A1J1GQH8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00210400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527522.1">
        <property type="nucleotide sequence ID" value="XM_028670806.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730631"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00210400"/>
    <dbReference type="OrthoDB" id="6921389at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="703"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="813"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1166"/>
            <end position="1204"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="25"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="706"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="814"/>
            <end position="847"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1614" mass="189869" checksum="F522FA1671CF0FC0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQZ9</accession>
    <name>A0A1J1GQZ9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Exosome complex exonuclease RRP6, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RRP6</name>
        <name evidence="6" type="ORF">PGAL8A_00208900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527507.1">
        <property type="nucleotide sequence ID" value="XM_028670790.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQZ9"/>
    <dbReference type="GeneID" id="39730616"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00208900"/>
    <dbReference type="OMA" id="FFWKMLK"/>
    <dbReference type="OrthoDB" id="2250022at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003727">
        <property type="term" value="F:single-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071044">
        <property type="term" value="P:histone mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071040">
        <property type="term" value="P:nuclear polyadenylation-dependent antisense transcript catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071039">
        <property type="term" value="P:nuclear polyadenylation-dependent CUT catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071036">
        <property type="term" value="P:nuclear polyadenylation-dependent snoRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071037">
        <property type="term" value="P:nuclear polyadenylation-dependent snRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071051">
        <property type="term" value="P:poly(A)-dependent snoRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.80">
        <property type="entry name" value="HRDC domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002121">
        <property type="entry name" value="HRDC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044876">
        <property type="entry name" value="HRDC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045092">
        <property type="entry name" value="Rrp6-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12124:SF47">
        <property type="entry name" value="EXOSOME COMPONENT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12124">
        <property type="entry name" value="POLYMYOSITIS/SCLERODERMA AUTOANTIGEN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00474">
        <property type="entry name" value="35EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="HRDC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50967">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HRDC" evidence="5">
        <location>
            <begin position="817"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="171"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="1019"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="187"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="206"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG94692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1099" mass="131221" checksum="BE5A89EAA3CFEB46" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR47</accession>
    <name>A0A1J1GR47_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">DNA-directed RNA polymerase subunit</fullName>
            <ecNumber evidence="14">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PGAL8A_00241300</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Forms the polymerase active center together with the second largest subunit. A single-stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol III. A bridging helix emanates from RPC1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol III by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 14">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the RNA polymerase beta' chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="14"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527828.1">
        <property type="nucleotide sequence ID" value="XM_028671147.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730941"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00241300"/>
    <dbReference type="OMA" id="INPFHVK"/>
    <dbReference type="OrthoDB" id="270392at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02583">
        <property type="entry name" value="RNAP_III_RPC1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.40.20:FF:000019">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.274.100:FF:000008">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.40.20:FF:000018">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.180">
        <property type="entry name" value="RNA polymerase ii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.120">
        <property type="entry name" value="RNA polymerase II, clamp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="entry name" value="RNA polymerase Rpb1, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006592">
        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007080">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007083">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044893">
        <property type="entry name" value="RNA_pol_Rpb1_clamp_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035697">
        <property type="entry name" value="RNAP_III_RPC1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038120">
        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015700">
        <property type="entry name" value="RPC1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006336">
        <property type="entry name" value="PRK08566.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48446">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' N-TERMINAL SECTION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48446:SF1">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA' N-TERMINAL SECTION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04997">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05000">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 14 16" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 14 16" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 14" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 14 16" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RNA polymerase N-terminal" evidence="15">
        <location>
            <begin position="242"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00058108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="CRG95015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2075" mass="242732" checksum="B5F1A1239DF7EB78" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR64</accession>
    <name>A0A1J1GR64_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Plasmepsin V, putative</fullName>
            <ecNumber evidence="14">3.4.23.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">PMV</name>
        <name evidence="14" type="ORF">PGAL8A_00235400</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Endomembrane system</location>
            <topology evidence="9">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.23.-" evidence="14"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527770.1">
        <property type="nucleotide sequence ID" value="XM_028671081.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR64"/>
    <dbReference type="GeneID" id="39730882"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00235400"/>
    <dbReference type="OMA" id="CGVHMEN"/>
    <dbReference type="OrthoDB" id="2747330at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06096">
        <property type="entry name" value="Plasmepsin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033866">
        <property type="entry name" value="Plasmepsin_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032861">
        <property type="entry name" value="TAXi_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13683">
        <property type="entry name" value="ASPARTYL PROTEASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13683:SF375">
        <property type="entry name" value="PEPTIDASE A1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14543">
        <property type="entry name" value="TAXi_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 11 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 11" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="504"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="13">
        <location>
            <begin position="59"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="119"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00046288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG94957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="552" mass="65284" checksum="BCAF1614E9F9F492" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR73</accession>
    <name>A0A1J1GR73_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00148100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526597.1">
        <property type="nucleotide sequence ID" value="XM_028675025.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR73"/>
    <dbReference type="GeneID" id="39730005"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00148100"/>
    <dbReference type="OMA" id="NFFYKYE"/>
    <dbReference type="OrthoDB" id="407343at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="599" mass="71752" checksum="6D4D08F7DD702047" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRF2</accession>
    <name>A0A1J1GRF2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00227100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527689.1">
        <property type="nucleotide sequence ID" value="XM_028670992.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRF2"/>
    <dbReference type="GeneID" id="39730798"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00227100"/>
    <dbReference type="OMA" id="NYEKCME"/>
    <dbReference type="OrthoDB" id="368431at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="81" mass="9447" checksum="12DC4BF2C9625157" modified="2017-02-15" version="1">MNNEIMKPFFPVVLNGCETISEKFFDCINKNLQPYGDEKSIENGMNQCQTLKINYEKCTEDKLKSLKGSLMFLTSYKEHKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRJ9</accession>
    <name>A0A1J1GRJ9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00256400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527972.1">
        <property type="nucleotide sequence ID" value="XM_028671306.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRJ9"/>
    <dbReference type="GeneID" id="39731092"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00256400"/>
    <dbReference type="OMA" id="KEYHPNV"/>
    <dbReference type="OrthoDB" id="368344at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="83" mass="10143" checksum="6E6B2C8F7FBB6E6E" modified="2017-02-15" version="1">MDKKVNIPYKTYDIKKFGFELPKEFQPNVKYGFFRNLFGDYSSYYLKSFLRVSSKVFAGFLLFYYPLDKVHCNIRRFKRNLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRN3</accession>
    <name>A0A1J1GRN3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00259600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528004.1">
        <property type="nucleotide sequence ID" value="XM_028671342.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRN3"/>
    <dbReference type="GeneID" id="39731125"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00259600"/>
    <dbReference type="OMA" id="IFFDKYD"/>
    <dbReference type="OrthoDB" id="391651at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="257"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="273"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="379" mass="45284" checksum="9BA86BC8EA24AA9F" modified="2017-02-15" version="1">MSLEVKLNERRRNTEVVYEGFGKINQEVKLGKRRSIKKNEEEEEEISKNLPFFINRKKRISENYDFMMNVSEDDTDVQQIADILHSYLNISESIGIRLSLLYKTKQYYMFKNYLIAIKDVLEGFHVLKVTRSGKLQNKKLYFNCYHMNIIGSWSKKILLYDEIIDISIGSSCTPELRIYENKFKDIEKRTYYVVLRTKYRDYSFLFLMDDEILKRDKNLSVLGTFKKLLKNKKNMNKKENSVNRTYHNLEIQENVITDSTKENSQKTEDKINDNNPKNINNKDIQINDKTDEEIDNNIRNFKNFLLTVLRSLKGIKINMNNEKMKAICKPSNKIYFDKYDFDNKKINSFFLFFQIQLDVCGPEIWFTSKFNDIIFTYKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRZ6</accession>
    <name>A0A1J1GRZ6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00260700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528015.1">
        <property type="nucleotide sequence ID" value="XM_028671354.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRZ6"/>
    <dbReference type="GeneID" id="39731136"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00260700"/>
    <dbReference type="OMA" id="LSVNHTQ"/>
    <dbReference type="OrthoDB" id="40823at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049500">
        <property type="entry name" value="Peptidase_M50B-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33979">
        <property type="entry name" value="OS02G0221600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33979:SF2">
        <property type="entry name" value="PEPTIDASE M50B-LIKE-DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13398">
        <property type="entry name" value="Peptidase_M50B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="242" mass="27927" checksum="4B6C2CD4B8BB557D" modified="2017-02-15" version="1">MDFDFTLKNCCEKNQNITFISISVCVIINIIFWRCKILEPFKLLTVFLHEFSHASACWITGGKVKGIEVNKNHGGCTNTIGGNQFLILPAGYIGSCFYGMFFILMAYLNKWTLIISAGFLCFLLLIVLIFYAKNVFLRILCVLFLTVTISIWVLCVYFKELDYWPLKIIMTFIGVLNEMYSMTDIFEDLITRTSYESDAYKYAELTKCNSKLCGVLWFLINLLFILLTIYLIGAIRVKYFGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS03</accession>
    <name>A0A1J1GS03_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00004600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528092.1">
        <property type="nucleotide sequence ID" value="XM_028671440.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS03"/>
    <dbReference type="GeneID" id="39728568"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00004600"/>
    <dbReference type="OrthoDB" id="372289at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="265"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="405"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="439"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="478"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="504"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="544"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="575"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="604" mass="72872" checksum="7FE62C9FEFA70C0E" modified="2017-02-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS21</accession>
    <name>A0A1J1GS21_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00003600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528082.1">
        <property type="nucleotide sequence ID" value="XM_028671429.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS21"/>
    <dbReference type="GeneID" id="39728558"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00003600"/>
    <dbReference type="OMA" id="NYFYIQK"/>
    <dbReference type="OrthoDB" id="370476at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1175" mass="142667" checksum="AF68CFC7FFD04599" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS71</accession>
    <name>A0A1J1GS71_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-editing substrate-binding complex 6 protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00011200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528156.1">
        <property type="nucleotide sequence ID" value="XM_028671511.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS71"/>
    <dbReference type="GeneID" id="39728634"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00011200"/>
    <dbReference type="OMA" id="DNVHMND"/>
    <dbReference type="OrthoDB" id="385235at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058917">
        <property type="entry name" value="RESC6_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26188">
        <property type="entry name" value="RESC6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA-editing substrate-binding complex 6 protein" evidence="1">
        <location>
            <begin position="216"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="RNA-editing substrate-binding complex 6 protein" evidence="1">
        <location>
            <begin position="389"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF26188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="677" mass="80889" checksum="AC05ED0E6E488487" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS91</accession>
    <name>A0A1J1GS91_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00162400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526736.1">
        <property type="nucleotide sequence ID" value="XM_028675179.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730149"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00162400"/>
    <dbReference type="OMA" id="LLQCVYI"/>
    <dbReference type="OrthoDB" id="386903at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1072"/>
            <end position="1092"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1203"/>
            <end position="1237"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1398"/>
            <end position="1469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1533" mass="180951" checksum="609E84F97267B1B5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSF8</accession>
    <name>A0A1J1GSF8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">KRR1 small subunit processome component</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">KRR-R motif-containing protein 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">KRR1</name>
        <name evidence="12" type="ORF">PGAL8A_00016800</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the ribosomal small subunit (SSU) processome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
            <location evidence="1 8">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the KRR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528210.1">
        <property type="nucleotide sequence ID" value="XM_028671571.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSF8"/>
    <dbReference type="GeneID" id="39728690"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00016800"/>
    <dbReference type="OMA" id="TPDIDKW"/>
    <dbReference type="OrthoDB" id="441223at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22393">
        <property type="entry name" value="KH-I_KRR1_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22394">
        <property type="entry name" value="KH-I_KRR1_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.10:FF:000014">
        <property type="entry name" value="KRR1 small subunit processome component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041174">
        <property type="entry name" value="KRR1-like_KH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048550">
        <property type="entry name" value="KRR1-like_KH1_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048548">
        <property type="entry name" value="KRR1-like_KH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048549">
        <property type="entry name" value="KRR1-like_KH2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024166">
        <property type="entry name" value="rRNA_assembly_KRR1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12581">
        <property type="entry name" value="HIV-1 REV BINDING PROTEIN 2, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12581:SF0">
        <property type="entry name" value="KRR1 SMALL SUBUNIT PROCESSOME COMPONENT HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17903">
        <property type="entry name" value="KH_KRR1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21800">
        <property type="entry name" value="KH_KRR1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006515">
        <property type="entry name" value="KRR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 8" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 8" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="KRR1 small subunit processome component first KH" evidence="10">
        <location>
            <begin position="46"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="KRR1 small subunit processome component second KH" evidence="11">
        <location>
            <begin position="129"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="247"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="247"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="291"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR006515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF21800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG95399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="301" mass="36229" checksum="C904F667C179C918" modified="2017-02-15" version="1">MSNVDGEKKKKKKYRKDKPWDNENIDHWKIEKFTREDNKHHFLEESSFKVLFPKYREKYLQQFSTDIKNVLNKHYVKFEINLIEGYMCVKTTKKTFDPYIIIKARDMISLLSRSVPFNHAKRVLEDEVFSDIIKISGFVRNKNKFIKRRQRLLGSNATTLKALEILTNCYICVHGKTVSVIGHFKSLKIVRRIIIDCMKNIHPVYHIKELIAKRELEKNENFKNENWEKYLPNFKKRNVQRRKIKEKLDKKKNKKKSVFPPDQLPRKIDIQMETGEYFLNNEKQKKKKKTEKNDDSLDSKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSM6</accession>
    <name>A0A1J1GSM6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00401600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527133.1">
        <property type="nucleotide sequence ID" value="XM_028670374.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSM6"/>
    <dbReference type="GeneID" id="39732546"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00401600"/>
    <dbReference type="OMA" id="NWENEHE"/>
    <dbReference type="OrthoDB" id="10366595at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="193"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="348" mass="41630" checksum="3B33B07213412E44" modified="2017-02-15" version="1">MQGDTVVYDTENKIEDKNTKRYVNTLFSNELNGNKKIHLNSGKLKNSKLFMNSKDNKLSKKENAHSTKHYPYLKKERELNEIISDEKNFIIKSGYKKEEKNESFIHESANTIYNNIFLKEKNLNDIYDFKNANKKNAYNSSNFIEDYIKKIKESNFNSVLNIIDSDIAKKKELYNKKVIEFNDFIYKVDCMYLQNWENEHEMANNEIESYIIQDKNMENEGKELLEVVENMISELRNLLQKIKKGIHINKDQMLNIQKEMNVLITRFQKIEEENYYSISQEGEYKYFLKKIGFQKKCRNMEFYQFYEKKLSEKKGKKYNTLSWNNLKNIANTKAKNVFKNFSNIFPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSP0</accession>
    <name>A0A1J1GSP0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">T-complex protein 1 subunit eta</fullName>
            <shortName evidence="10">TCP-1-eta</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">CCT-eta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">CCT7</name>
        <name evidence="11" type="ORF">PGAL8A_00007600</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 10">Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Heterooligomeric complex that forms two stacked rings.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528121.1">
        <property type="nucleotide sequence ID" value="XM_028671472.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSP0"/>
    <dbReference type="GeneID" id="39728598"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00007600"/>
    <dbReference type="OMA" id="HRKGNTW"/>
    <dbReference type="OrthoDB" id="1935484at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03340">
        <property type="entry name" value="TCP1_eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000017">
        <property type="entry name" value="T-complex protein 1 subunit eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000006">
        <property type="entry name" value="T-complex protein 1 subunit eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012720">
        <property type="entry name" value="Chap_CCT_eta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054827">
        <property type="entry name" value="thermosome_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02345">
        <property type="entry name" value="chap_CCT_eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041082">
        <property type="entry name" value="thermosome_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG95310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="539" mass="59648" checksum="DC3B612BF52B3138" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT32</accession>
    <name>A0A1J1GT32_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00018500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528227.1">
        <property type="nucleotide sequence ID" value="XM_028671590.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT32"/>
    <dbReference type="GeneID" id="39728707"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00018500"/>
    <dbReference type="OMA" id="ICSFKSQ"/>
    <dbReference type="OrthoDB" id="185175at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="1">
        <location>
            <begin position="2"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="120" mass="14615" checksum="FE213A127698C11E" modified="2017-02-15" version="1">MEIVNEGWVFKQSKYLKKLRKRYIILTKNFICSFKSQYYQGEKPTEILYLNKFTELTSIEDIRKIKLIENELGLTNIHLFNIRYNNRKILFVTLDKDENNRWIKNISKQMVKPTVLMNEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTB0</accession>
    <name>A0A1J1GTB0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00193200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000029">
        <property type="protein sequence ID" value="CRG94534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527349.1">
        <property type="nucleotide sequence ID" value="XM_028670614.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTB0"/>
    <dbReference type="GeneID" id="39730457"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00193200"/>
    <dbReference type="OMA" id="ENINGCR"/>
    <dbReference type="OrthoDB" id="372940at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="367" mass="43982" checksum="608557ADB0E8C1D6" modified="2017-02-15" version="1">MNDNGTIENNIDTIKINSKRLREKKCEHKNDLDDNIIRNDIKVNLYVNNIKDKEKKNTILRNRCSEKKNGKDLRTYKNTRVIKKSNKKRTKEENSKNIKGNNENIKKKKENYSNKSKNERKENRKNENNVNTDKKNNINKKKQINKNSKINKKKIMKDSNSNTRNIKLSCEKNFYNTSKKKEKEKEKEKEKEEKRERVREKEKQSKNVCGKNVFVKLSDIKKKLSQYTKKKKKEKEIIEVISDKEYEIYTSENKKKKKIKVSYNKNTKNISEENINGCRIKNNENKNKNQKDIFNTFEINGIEIKNNKYICKFKDKLNKTHKYFFPIYKYGDEKTAKKKAILLKFHMYSCLYCQNGILCNFVENYIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTC5</accession>
    <name>A0A1J1GTC5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Microneme associated antigen, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">MA</name>
        <name evidence="2" type="ORF">PGAL8A_00400300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527120.1">
        <property type="nucleotide sequence ID" value="XM_028670360.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTC5"/>
    <dbReference type="GeneID" id="39732533"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00400300"/>
    <dbReference type="OMA" id="QLIYSYY"/>
    <dbReference type="OrthoDB" id="372164at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="265" mass="32051" checksum="98A41E33A0A1A91B" modified="2017-02-15" version="1">MHDYFIKNKFNLLNSNLFNNIYRRDSKYFKEEVKNDRRKVYLDKEENEKINKNEELIDRMKKDFHEQLIYSYYNNFNEKSVEEIKDKNNDLKNIYDYNNINKKSLLNYNSNEISEDICLKNKEVKEDILYNEFKKLKNDVLVLQMMNVNLQKQLLSNHLMNSSKVIPQNIIINNKTEVASNAISQIQDNKKKKGFLYLLFKKILRSRFNQMLFVSSIFLSFFLINKHWQRALKVSQLEKRINSNILLRSVRLFEETLGIRKLSYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTD6</accession>
    <name>A0A1J1GTD6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">eIF3h C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00291500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528519.1">
        <property type="nucleotide sequence ID" value="XM_028671914.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTD6"/>
    <dbReference type="GeneID" id="39731448"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00291500"/>
    <dbReference type="OrthoDB" id="10265695at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045810">
        <property type="entry name" value="eIF3h_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19445">
        <property type="entry name" value="eIF3h_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="eIF3h C-terminal" evidence="2">
        <location>
            <begin position="309"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="480" mass="56287" checksum="9B5D18D70E77C8EC" modified="2017-02-15" version="1">MKYVPPPLRVPDEIKEKEEALKVSEQEKQKEELKIEKTETDSDSSTEGDDFEIVLNSVVVSQILKNRDLRGELLGYYIKNDDGKSKKKKKKKVKISDGDNKEKELEEDEEVDEEGDEEEDEQEEEQDENDDRKKKKKDSNNEQKKNKKNDAKKLDVVEINQSFCVCNIEDICIDKINKISSKYQLPKQKYNDLLNNLILYFNKNKYEEEGEKYINEVNNYYDDYVNIMAELNFETTSFGFYINVNDIKKKEVLATLILYSLINKNAFVLCFGEKYGKLIFSAYKVDVDVIFDIRKQIKNSNFNQFSDILNVELKKNGLSSKNILQKIPVRIKNSIINSLFLKILKNKNKNYISSKDYLNSLEVDSLENHVQETCKSLELLKSEQEKIVKYKKDVFKQLQSQKVYQEKKKLEKEKNKIVHDNLDTNEEDINIQNIFKNIPQPSLLFPYVLTMSNNMLNDNINNLCSHAIAKSYLYYKNAKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTG5</accession>
    <name>A0A1J1GTG5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Apyrase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00303400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GDA1/CD39 NTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528630.1">
        <property type="nucleotide sequence ID" value="XM_028672037.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTG5"/>
    <dbReference type="GeneID" id="39731567"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00303400"/>
    <dbReference type="OrthoDB" id="6372431at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017110">
        <property type="term" value="F:nucleoside diphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009134">
        <property type="term" value="P:nucleoside diphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd24003">
        <property type="entry name" value="ASKHA_NBD_GDA1_CD39_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.150">
        <property type="entry name" value="Exopolyphosphatase. Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000407">
        <property type="entry name" value="GDA1_CD39_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11782">
        <property type="entry name" value="ADENOSINE/GUANOSINE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11782:SF83">
        <property type="entry name" value="GUANOSINE-DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01150">
        <property type="entry name" value="GDA1_CD39"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="854"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="712"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="712"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="225"/>
            <end position="229"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600407-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600407-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="888" mass="105574" checksum="41B78CC62CC35F44" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU04</accession>
    <name>A0A1J1GU04_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">mannose-1-phosphate guanylyltransferase</fullName>
            <ecNumber evidence="3">2.7.7.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00292700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; GDP-alpha-D-mannose from alpha-D-mannose 1-phosphate (GTP route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.13" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528531.1">
        <property type="nucleotide sequence ID" value="XM_028671927.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU04"/>
    <dbReference type="GeneID" id="39731460"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00292700"/>
    <dbReference type="OMA" id="GPNCWIC"/>
    <dbReference type="OrthoDB" id="1733332at2759"/>
    <dbReference type="UniPathway" id="UPA00126">
        <property type="reaction ID" value="UER00930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004475">
        <property type="term" value="F:mannose-1-phosphate guanylyltransferase (GTP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009298">
        <property type="term" value="P:GDP-mannose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06425">
        <property type="entry name" value="M1P_guanylylT_B_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000013">
        <property type="entry name" value="mannose-1-phosphate guanyltransferase beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056729">
        <property type="entry name" value="GMPPB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045233">
        <property type="entry name" value="GMPPB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050486">
        <property type="entry name" value="Mannose-1P_guanyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22572">
        <property type="entry name" value="SUGAR-1-PHOSPHATE GUANYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25087">
        <property type="entry name" value="GMPPB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleotidyl transferase" evidence="7">
        <location>
            <begin position="3"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="Mannose-1-phosphate guanyltransferase C-terminal" evidence="8">
        <location>
            <begin position="297"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF25087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG95723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="408" mass="46629" checksum="D927BD16D1BE1D33" modified="2017-02-15" version="1">MNALILVGGYGTRLRPLTLTTPKPLINFCNKPILEHQIFNLAKCGIKEIILAIAYKPTDITNFVKELEKKYDVKIYYSIENEPLGTGGPIKLAENYLNKYDDFFVFNSDIICSFPLREMMNFHKENNSQLTILVKEVEDPRAFGVVITEGKKITKFEEKPLVPKSSLINAGIYILNKNILNLIPKKNTSLEKEIFPKLANERILYFYKLNKFWADIGKPLDFLRGQELYLKDLEEKKDDEKSLHDYLCICYNIKEEIEPKNCDKKNLYITFENIEELNKFIGNKNNFFNNVLPHTKIEGNVLISSKTVIKKNCVLGDNVVLGDNVIVGEGCRIKNSCVMNNSIIESYTYIENSIIGSKSSVGKWSRIEGLCVLGESVILESEIFLNNAFILPFKKVNDSIYEKGAVIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU18</accession>
    <name>A0A1J1GU18_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribosome quality control complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00319100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NEMF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528786.1">
        <property type="nucleotide sequence ID" value="XM_028672212.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731724"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00319100"/>
    <dbReference type="OMA" id="ANWEKIW"/>
    <dbReference type="OrthoDB" id="207084at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990112">
        <property type="term" value="C:RQC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072344">
        <property type="term" value="P:rescue of stalled ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990116">
        <property type="term" value="P:ribosome-associated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.310.10:FF:000003">
        <property type="entry name" value="Zinc knuckle domain containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.310.10">
        <property type="entry name" value="ibrinogen binding protein from staphylococcus aureus domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021846">
        <property type="entry name" value="NFACT-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008532">
        <property type="entry name" value="NFACT_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051608">
        <property type="entry name" value="RQC_Subunit_NEMF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15239">
        <property type="entry name" value="NUCLEAR EXPORT MEDIATOR FACTOR NEMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15239:SF6">
        <property type="entry name" value="RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT NEMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11923">
        <property type="entry name" value="NFACT-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05670">
        <property type="entry name" value="NFACT-R_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NFACT RNA-binding" evidence="8">
        <location>
            <begin position="745"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="domain" description="NFACT protein C-terminal" evidence="9">
        <location>
            <begin position="2423"/>
            <end position="2505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="424"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1449"/>
            <end position="1514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1825"/>
            <end position="1846"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1993"/>
            <end position="2339"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="546"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="685"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1884"/>
            <end position="1911"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="433"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1449"/>
            <end position="1461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1503"/>
            <end position="1512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1993"/>
            <end position="2009"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="2016"/>
            <end position="2025"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="2026"/>
            <end position="2242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="2248"/>
            <end position="2260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="2270"/>
            <end position="2288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="2296"/>
            <end position="2305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="2325"/>
            <end position="2337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00070414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF11923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG95978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2533" mass="298477" checksum="EB89ABEA1EFC7426" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU68</accession>
    <name>A0A1J1GU68_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">WD and tetratricopeptide repeats protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00299900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528595.1">
        <property type="nucleotide sequence ID" value="XM_028671998.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731532"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00299900"/>
    <dbReference type="OMA" id="FCYRNSI"/>
    <dbReference type="OrthoDB" id="4869960at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080008">
        <property type="term" value="C:Cul4-RING E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045717">
        <property type="term" value="P:negative regulation of fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045151">
        <property type="entry name" value="DCAF8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15574:SF40">
        <property type="entry name" value="WD AND TETRATRICOPEPTIDE REPEATS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15574">
        <property type="entry name" value="WD REPEAT DOMAIN-CONTAINING FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="48"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1849"/>
            <end position="1881"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="553"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1082"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1323"/>
            <end position="1396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1563"/>
            <end position="1661"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="781"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="560"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="627"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="661"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="676"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1083"/>
            <end position="1124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1585"/>
            <end position="1598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1599"/>
            <end position="1617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1630"/>
            <end position="1639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1640"/>
            <end position="1651"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1940" mass="232087" checksum="87EE9EAF44CC24EC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUD8</accession>
    <name>A0A1J1GUD8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Dihydroorotase, putative</fullName>
            <ecNumber evidence="5">3.5.2.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00232500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.3" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527741.1">
        <property type="nucleotide sequence ID" value="XM_028671049.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUD8"/>
    <dbReference type="GeneID" id="39730852"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00232500"/>
    <dbReference type="OMA" id="TLHHISM"/>
    <dbReference type="OrthoDB" id="1670005at2759"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00117"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004151">
        <property type="term" value="F:dihydroorotase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00219">
        <property type="entry name" value="PyrC_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004721">
        <property type="entry name" value="DHOdimr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002195">
        <property type="entry name" value="Dihydroorotase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43137">
        <property type="entry name" value="DIHYDROOROTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43137:SF1">
        <property type="entry name" value="DIHYDROOROTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001237">
        <property type="entry name" value="DHOdimr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00483">
        <property type="entry name" value="DIHYDROOROTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="360" mass="42090" checksum="6350609D84E759A5" modified="2017-02-15" version="1">MFESIFLPIADDMHCHLRQDDMLKFTVDAIKKGGCNRVLVMPNTTPIISSCEDAKNYKNELMKYDNTIDYLMTLYLNKKTDENDILNNYKECNFQGIKIYPNNVTTNSKEGIETLEPYYKIFSTLEKLNKSLHIHCEEPNINPLYAEKNYLDHIHDLAVKFPHLKIVLEHISTVDTINIIKKFQNLAGSVTPHHLYLTIDDVVNLNEYDFSLDNVNIEKYIKNVYNYCKPIPKTIDDKIALCNIIKEDFPRIFLGSDSAPHKREHKNNPYFKPGIYTQPFLLSYLSHIFNRIDCLDKLENFACKNAARFLNLKEKKLNEGELAVYIEKKKFKIPNEYFDVIPFLSGQTIDFTVSYKYYNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUE6</accession>
    <name>A0A1J1GUE6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleoporin NUP116/NSP116, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">NUP116</name>
        <name evidence="2" type="ORF">PGAL8A_00233300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527749.1">
        <property type="nucleotide sequence ID" value="XM_028671058.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUE6"/>
    <dbReference type="GeneID" id="39730860"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00233300"/>
    <dbReference type="OMA" id="KDPQYYN"/>
    <dbReference type="OrthoDB" id="273123at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040184">
        <property type="entry name" value="Mcm10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055065">
        <property type="entry name" value="OB_MCM10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13454">
        <property type="entry name" value="PROTEIN MCM10 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13454:SF11">
        <property type="entry name" value="PROTEIN MCM10 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22379">
        <property type="entry name" value="OB_MCM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM10 OB-fold" evidence="1">
        <location>
            <begin position="32"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="466" mass="55481" checksum="A9A2560F1769023A" modified="2017-02-15" version="1">MENKESIIIDKNKIKANDIHLNIKEWITSIEDCEAFFRNRKIMYFSDYLSKFDDDIKNKIENEEIIIICTVVNIPYKVRKYNEEKYIFWDISDLKETQSRLFLSGEICEENENEKEGVVVALINPLMKEKDPQYYNSRILEIHKKNNLRLIGLIDGLERCKGITKSGSNCKITLYAPLYGYYCKYHIKQNKTHKKRKQINNENDENKNDDKKCIKSIDIDTKDSLNNNDNYKKNSKKKKEEKDIDTEEYFDVESIIGMYSKKVVAKDKKKKIEIINKRIKELDDYAKLNKNENYLDAIKNDTMKQECSTQKSVNDIFSEQCPELIYLINKSNKITEKEENKNEDLKMKEDINTINENIVSYEEKQKRKFENFLSKLIELQKSKDENDMKTLLKGLIYVTNNFNFHLKHIENSNIFDICYKLMDHRNEEIAIAALKFKRKINNLYIDYYKNRLKKHKVETSGDKNNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUQ4</accession>
    <name>A0A1J1GUQ4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00324600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000051">
        <property type="protein sequence ID" value="CRG96033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528841.1">
        <property type="nucleotide sequence ID" value="XM_028672272.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUQ4"/>
    <dbReference type="GeneID" id="39731779"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00324600"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="292"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="326" mass="38014" checksum="0789B84A2625E4D9" modified="2017-02-15" version="1">MALLYNEGCEITKGEVTECFMRICPLDSHKYTSVFCSYGLLPTKAENHSNDRLNDLSKNIFKFQHYKPYNHSRIIFLSNNDVDGIVFLFEYKSFSYKYPNKTYLCRFRKISQKATICEHIDASYLGKTLSFNSYDVINGTDNIINIRRSKNSKHTITEFKYRDLSFGRSACHILKGKYIENKPCMFYLCEDVNGNLSCFSANYNGRLIYTDKFSDNSLENRQFLYLPGSCLTKDSNFICDAQLCQFKGIKELTSCEKLEISSIKNIFPSRGIIEPAPTYMPISHENRPSSSILLATSLLPFLVMLVFIWCFVYKFLRRRKRKAYRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUR5</accession>
    <name>A0A1J1GUR5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SAM-dependent RNA methyltransferase, putative</fullName>
            <ecNumber evidence="1">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00244700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527861.1">
        <property type="nucleotide sequence ID" value="XM_028671183.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUR5"/>
    <dbReference type="GeneID" id="39730975"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00244700"/>
    <dbReference type="OMA" id="LEYIHIC"/>
    <dbReference type="OrthoDB" id="373498at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035241">
        <property type="term" value="F:protein-arginine omega-N monomethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18090">
        <property type="entry name" value="Arginine_MT_Sfm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007364">
        <property type="entry name" value="SFM1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35517">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE SFM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35517:SF1">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE SFM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04252">
        <property type="entry name" value="SFM1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="213" mass="25138" checksum="132D84EABF7A3ABE" modified="2017-02-15" version="1">MPTKYIIEHLDELEEWCILEYIHICDIVKDINTIFTKFDAKFSDICNTHKPTCYSESINDLKDNFNWDKICLLDMKAEKTLKCEDKNKIDFLLFGGILGNVPSDDRTSELRKYNFPISRNLGNIQMTTNTAVLVCYIILNDNIELENIPFVDKPEIYLKNNKESIILPFRFVSKYYYTKNEKDRNVPVLPRNFMEYLIKLGDQQFDVNTFLNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUS5</accession>
    <name>A0A1J1GUS5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">AP complex subunit sigma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00344700</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasmic vesicle</location>
            <location evidence="2">Clathrin-coated vesicle membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the adaptor complexes small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529034.1">
        <property type="nucleotide sequence ID" value="XM_028672486.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUS5"/>
    <dbReference type="GeneID" id="39731977"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00344700"/>
    <dbReference type="OMA" id="KAYHILD"/>
    <dbReference type="OrthoDB" id="371463at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030121">
        <property type="term" value="C:AP-1 adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035615">
        <property type="term" value="F:clathrin adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016482">
        <property type="term" value="P:cytosolic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd14831">
        <property type="entry name" value="AP1_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000007">
        <property type="entry name" value="AP complex subunit sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044733">
        <property type="entry name" value="AP1_sigma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016635">
        <property type="entry name" value="AP_complex_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11753">
        <property type="entry name" value="ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015588">
        <property type="entry name" value="AP_complex_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AP complex mu/sigma subunit" evidence="10">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR015588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG96229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="155" mass="18231" checksum="966067EF0F3057DC" modified="2017-02-15" version="1">MIHFVLLISRQGKTRLAKWYIPLSQKEKAKIIRETSQITLNRTPKLCNFVEWREYKLVFKRYASLFFITCIDKNDNELITLEIIHHYVEILDKYFGNVCELDLIFNFHKAYYLLDEILVTGELQESSKKTVLRVVAAQDALMEDNKSSKKLGAII</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUU3</accession>
    <name>A0A1J1GUU3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA mismatch repair protein MLH, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00344400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529031.1">
        <property type="nucleotide sequence ID" value="XM_028672483.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUU3"/>
    <dbReference type="GeneID" id="39731974"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00344400"/>
    <dbReference type="OMA" id="ANYHVKK"/>
    <dbReference type="OrthoDB" id="10263226at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032389">
        <property type="term" value="C:MutLalpha complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16926">
        <property type="entry name" value="HATPase_MutL-MLH-PMS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000079">
        <property type="entry name" value="DNA mismatch repair protein MLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000014">
        <property type="entry name" value="DNA mismatch repair protein Mlh1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014762">
        <property type="entry name" value="DNA_mismatch_repair_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013507">
        <property type="entry name" value="DNA_mismatch_S5_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032189">
        <property type="entry name" value="Mlh1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002099">
        <property type="entry name" value="MutL/Mlh/PMS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00585">
        <property type="entry name" value="mutl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073:SF12">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01119">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16413">
        <property type="entry name" value="Mlh1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01340">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00058">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair protein S5" evidence="6">
        <location>
            <begin position="297"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="840" mass="98283" checksum="AD8F7C750AC59CB2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV57</accession>
    <name>A0A1J1GV57_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">T-complex protein 1 subunit alpha</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">CCT-alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">TCP1</name>
        <name evidence="10" type="ORF">PGAL8A_00359700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529178.1">
        <property type="nucleotide sequence ID" value="XM_028672647.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV57"/>
    <dbReference type="GeneID" id="39732127"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00359700"/>
    <dbReference type="OMA" id="RGPNDYQ"/>
    <dbReference type="OrthoDB" id="496at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03335">
        <property type="entry name" value="TCP1_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000009">
        <property type="entry name" value="T-complex protein 1 subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000070">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012715">
        <property type="entry name" value="Chap_CCT_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054827">
        <property type="entry name" value="thermosome_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02340">
        <property type="entry name" value="chap_CCT_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041082">
        <property type="entry name" value="thermosome_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG96373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="543" mass="60077" checksum="28999DF68DC2F26D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV80</accession>
    <name>A0A1J1GV80_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00334900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528939.1">
        <property type="nucleotide sequence ID" value="XM_028672381.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV80"/>
    <dbReference type="GeneID" id="39731879"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00334900"/>
    <dbReference type="OMA" id="KNIMYIR"/>
    <dbReference type="OrthoDB" id="188741at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035082">
        <property type="term" value="P:axoneme assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037386">
        <property type="entry name" value="CCDC40"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16275">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16275:SF8">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="306"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="523"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="718"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1008" mass="120818" checksum="5B5C72A635E98649" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVC2</accession>
    <name>A0A1J1GVC2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00238400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527800.1">
        <property type="nucleotide sequence ID" value="XM_028671116.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVC2"/>
    <dbReference type="GeneID" id="39730912"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00238400"/>
    <dbReference type="OMA" id="EVWELYI"/>
    <dbReference type="OrthoDB" id="376157at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="264" mass="31904" checksum="3EC95BEC5E6F5F72" modified="2017-02-15" version="1">MNENKRTALLEKKNEEISTILNKNILFKCNNTNDLKETFVNIKTDYSLESEKEKSNISLFNVFKKKLKEERYFSRFLIIFKISNDINEKKYINETLNFILKENYKLITGISLFVNIYSIMLLECIDSKYIFSFLKNLNNIKYISDIEILYFNELNKQNINDSFNFYEYNKEEPKSICSNECNYIDEVWELYINILNLCCHIKNNKDKQNIFDQNDNIKKNFSLLENFFHENAKQYIWNLKDFISFFVEDFKLPIDDFSDDFLDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVD3</accession>
    <name>A0A1J1GVD3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase fold domain containing protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00347000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529057.1">
        <property type="nucleotide sequence ID" value="XM_028672512.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVD3"/>
    <dbReference type="GeneID" id="39732000"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00347000"/>
    <dbReference type="OMA" id="GNNTDMG"/>
    <dbReference type="OrthoDB" id="446723at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277">
        <property type="entry name" value="ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277:SF81">
        <property type="entry name" value="PROTEIN ABHD13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="1">
        <location>
            <begin position="128"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="361" mass="41976" checksum="4DF7E29AB7F4179C" modified="2017-02-15" version="1">MNNISFDIDIQNMKERNGDEENENKNIDKMNSEVVLQSSKLKYLFCFLGCLTLCGLRTSIVRKMAFSPPSLKGYLVENNKFVCNHVKSIEFYEAVRRNNIGINFILIKKHLNKIASILIYRKPLNFNKQIILFSHGNSTDIGHMCLFFLNLVLYNDVNILAYDYSGYGYSNKKPSEKNIYKNIKIVYKHLIKELKINPLNIIVYGHSIGTACSCYLISLKKVQVGGCILQSPLASGLRLLIPYENQKLPWFDVFKNVDRLKKVSLLPIFLMHGKRDKQVPFNHAVCLMNILKENFEKRNLKNNSLKNFEEKKNLDNLSLINFWAIEDADHNDIEEKNTVVFYHKIKEFLLLCENFNKNKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVF1</accession>
    <name>A0A1J1GVF1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cysteine-rich PDZ-binding protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Cysteine-rich interactor of PDZ three</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">CRIPT</name>
        <name evidence="9" type="ORF">PGAL8A_00372800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CRIPT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529308.1">
        <property type="nucleotide sequence ID" value="XM_028672791.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVF1"/>
    <dbReference type="GeneID" id="39732258"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00372800"/>
    <dbReference type="OMA" id="MPCDKCE"/>
    <dbReference type="OrthoDB" id="147332at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031122">
        <property type="term" value="P:cytoplasmic microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019367">
        <property type="entry name" value="PDZ-binding_CRIPT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11805">
        <property type="entry name" value="CYSTEINE-RICH PDZ-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11805:SF1">
        <property type="entry name" value="CYSTEINE-RICH PDZ-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10235">
        <property type="entry name" value="Cript"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0747">Spliceosome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG96503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="90" mass="10195" checksum="6D67F21B52B82D68" modified="2017-02-15" version="1">MPCEKCEKKLKKLPTPDINNSSNRSIGVNKLLEYHNNKQKFNPNSSKCKKCNSQLHYDGKYCSICSYKLGKCHLCGKTIADNSSHNMSII</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVF7</accession>
    <name>A0A1J1GVF7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">VPS9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00366700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529247.1">
        <property type="nucleotide sequence ID" value="XM_028672723.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVF7"/>
    <dbReference type="GeneID" id="39732197"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00366700"/>
    <dbReference type="OMA" id="IHLHMYI"/>
    <dbReference type="OrthoDB" id="411646at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003123">
        <property type="entry name" value="VPS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037191">
        <property type="entry name" value="VPS9_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02204">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109993">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51205">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VPS9" evidence="1">
        <location>
            <begin position="225"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="374" mass="44231" checksum="791EC606EBE22BB2" modified="2017-02-15" version="1">MNNHPVISILFNKYKNLYDSLISNTHIILLPEAKTLLNTNIDIEFIKKHIFRKSHLKNIYINLHDQCIEIDSKYISTSYGFEENRKCEIIKEEINSNDKFSRVIFINLPLEEHEKNLSVNYTTINENDKNILDYKNDLTLFFNKNSKCKEFIDSEILQFAYSYIIVTGYENFIGRKILNIVNDTLKLQNSDNEKNFSNDIKIPLIKYIYSYLHRVIWKHLIKNYEKIECKIQKKMNTLRNNIITFLKKSNLENFSLFHIETISFHLKQIEKFSNPIDKIYILDNISDIICEIIFKTNINLKEKNSEIYDVNSDSLIAILAAAIAYSQIKYIISHSIHLHMYIDNLSTSEKIDKLSFIFTIFHSSIIYLCDMNDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVM4</accession>
    <name>A0A1J1GVM4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00374700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529327.1">
        <property type="nucleotide sequence ID" value="XM_028672812.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732277"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00374700"/>
    <dbReference type="OMA" id="MRWTGHK"/>
    <dbReference type="OrthoDB" id="41566at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042054">
        <property type="term" value="F:histone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016274">
        <property type="term" value="F:protein-arginine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025799">
        <property type="entry name" value="Arg_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006:SF53">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="372"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1312"/>
            <end position="1382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="372"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1351"/>
            <end position="1373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1460" mass="171843" checksum="9ABAFECCEE014E96" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVS5</accession>
    <name>A0A1J1GVS5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00365300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529233.1">
        <property type="nucleotide sequence ID" value="XM_028672707.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVS5"/>
    <dbReference type="GeneID" id="39732183"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00365300"/>
    <dbReference type="OMA" id="NEMVREH"/>
    <dbReference type="OrthoDB" id="392554at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="31"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="479" mass="56657" checksum="0163F411C7256142" modified="2017-02-15" version="1">MKKNKEAYDRQIKIEKKYILDILKENDCETIEELKNLVTFLNNENKRLHSINVESLKKINILSVRVKNLEKLTKNYNEQFYQNKLSYIKKYEKKLNYLNNQLSILTNYTKDKENEYNRLIEEQDKYFKNFFINLNKSINLIISYDKDKNYSPCDDSSSNSSSIKIKKNEETFSDSKIRNNTFSSSSLSNASYFNNNNIKDKNNQILKKKNKDDIVNEDVNNKKQNYIESDISDNLNKVKLQEDLFDKLNHLSSSKDVKNNKEDMYKNIEKIKSLSESIKNIDNELLHYKNTDFHEEKELPFYSKQMTKLDNSLNNFTCIEFEKKKNIKVEKEIEESPNLSENKASEDKLLVDTALCKTVEGSKIEAHKTLNKIIDYNIDIKNRLNNLLEDMYIEDNKKKDILINNNSNNNIFNNFSKTMNSKNNIMDIFNDKLNITCLGDINNSRPKYVKFNTIHREIMNPRQNFFTQNKSSIDHIICL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVW1</accession>
    <name>A0A1J1GVW1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Phospholipid or glycerol acyltransferase, putative</fullName>
            <ecNumber evidence="14">2.3.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PGAL8A_00427000</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="14"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529494.1">
        <property type="nucleotide sequence ID" value="XM_028672997.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVW1"/>
    <dbReference type="GeneID" id="39732802"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00427000"/>
    <dbReference type="OMA" id="WRTITCT"/>
    <dbReference type="OrthoDB" id="272512at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07991">
        <property type="entry name" value="LPLAT_LPCAT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045252">
        <property type="entry name" value="LPCAT1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23063:SF52">
        <property type="entry name" value="LYSOPHOSPHATIDYLCHOLINE ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23063">
        <property type="entry name" value="PHOSPHOLIPID ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 14" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="13">
        <location>
            <begin position="56"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="14">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG96690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="287" mass="33699" checksum="6794E7846126B8D7" modified="2017-02-15" version="1" fragment="single">VIISFLLRNTNENEDSPILKFYLKFLKMVCRISLWIFGINKIESHYLCDKEWPKNIVSNHVSALDPFYFISEHACSFVAKKSLRKDRFIGASVLALKCVFVYREKLEDRKKALESIKERQLLVNDKKNNYPSFVIFSEGTTSNGMQIIEQKKGAFFSLLPITPVLLVYDYDIFNPSYDILPFTWWVFLSAANYQSMELRTYWLPKVYPPDEPEHANLTEEEKINIFHDKVSKIMFQNMKKYNPKAPQDIDDYNDWPGSLRLKVDYFQTALGKVATKQLNKEKNLSEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVY3</accession>
    <name>A0A1J1GVY3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 4C</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00370900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the eIF-1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529289.1">
        <property type="nucleotide sequence ID" value="XM_028672770.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVY3"/>
    <dbReference type="GeneID" id="39732239"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00370900"/>
    <dbReference type="OMA" id="KMEDQEY"/>
    <dbReference type="OrthoDB" id="274995at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05793">
        <property type="entry name" value="S1_IF1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000071">
        <property type="entry name" value="Eukaryotic translation initiation factor 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00216">
        <property type="entry name" value="aIF_1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006196">
        <property type="entry name" value="RNA-binding_domain_S1_IF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001253">
        <property type="entry name" value="TIF_eIF-1A"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00523">
        <property type="entry name" value="eIF-1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21668">
        <property type="entry name" value="EIF-1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01176">
        <property type="entry name" value="eIF-1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00652">
        <property type="entry name" value="eIF1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50832">
        <property type="entry name" value="S1_IF1_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 9" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1-like" evidence="8">
        <location>
            <begin position="22"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="99"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="99"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="115"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="138"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG96484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="151" mass="17317" checksum="11B2A4F5EF1D811E" modified="2017-02-15" version="1">MPKNKGKGGKNRRRGKNDNEGEKRELLYKEEGQEYAQVLRMLGNGRLEAHCFDGVKRLCHIRKRVWINSGDIILVSLRDYQDSKADVIAKYTPDEARSLKTHGELPETAKINETDIFDDDGQNGVEFLDDETDEEAQEDSHNARKLDIEDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW30</accession>
    <name>A0A1J1GW30_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00369500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529275.1">
        <property type="nucleotide sequence ID" value="XM_028672753.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW30"/>
    <dbReference type="GeneID" id="39732225"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00369500"/>
    <dbReference type="OrthoDB" id="380547at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="673" mass="80522" checksum="BE15F5181008D672" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW33</accession>
    <name>A0A1J1GW33_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00375700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000060">
        <property type="protein sequence ID" value="CRG96532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529337.1">
        <property type="nucleotide sequence ID" value="XM_028672823.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW33"/>
    <dbReference type="GeneID" id="39732287"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00375700"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="293"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="327" mass="38203" checksum="2D39BCCB2D259B80" modified="2017-02-15" version="1">MALLYNDGCENLKGEIIKCFMRICPLNSIKFTPLTCNYNIFPVKAENDSNNKLNDLSNNIFKYQRYEPYNHSRIIFLSNNDVDGIVFLYEENMYAYENPSKTYLCRLRKISQKATICEHIDASYLGKTLSFNSYDVINRNYNDIINIRRSKNSKHTVTKLKYRDLSFGRNTCHIVKTKYIEENNCMYHLCEVVNGHLSCFNANYSGRLIFIDDILDNSIEKRKFLYLPGSCLTKDSNFICDPQLCQYNSTQKLTSCEKLEISSIKNIIPSRGTLEPAPTYMPISHENRPSTSILLATSLMPFLVMLVFIWCFVYKFLRSRKRKVYSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW44</accession>
    <name>A0A1J1GW44_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00264100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528048.1">
        <property type="nucleotide sequence ID" value="XM_028671391.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731170"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00264100"/>
    <dbReference type="OMA" id="ESQDRSM"/>
    <dbReference type="OrthoDB" id="1936883at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="182"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="304"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="367"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="430"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="619"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="762"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="192"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="205"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="238"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1460" mass="166154" checksum="4C21CB8B37FE07E8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWA6</accession>
    <name>A0A1J1GWA6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Exoribonuclease II, putative</fullName>
            <ecNumber evidence="3">3.1.13.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RNaseII</name>
        <name evidence="3" type="ORF">PGAL8A_00418600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.1" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529409.1">
        <property type="nucleotide sequence ID" value="XM_028672903.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732717"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00418600"/>
    <dbReference type="OMA" id="MMILTNF"/>
    <dbReference type="OrthoDB" id="372421at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008859">
        <property type="term" value="F:exoribonuclease II activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050180">
        <property type="entry name" value="RNR_Ribonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355:SF9">
        <property type="entry name" value="DIS3-LIKE EXONUCLEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355">
        <property type="entry name" value="RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNB" evidence="2">
        <location>
            <begin position="695"/>
            <end position="1132"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="401"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="507"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1616" mass="194124" checksum="DF900F96E0D6060F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWE3</accession>
    <name>A0A1J1GWE3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Palmitoyltransferase</fullName>
            <ecNumber evidence="10">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">DHHC6</name>
        <name evidence="12" type="ORF">PGAL8A_00445600</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="10"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529678.1">
        <property type="nucleotide sequence ID" value="XM_028673202.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWE3"/>
    <dbReference type="GeneID" id="39732989"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00445600"/>
    <dbReference type="OMA" id="CCNEKKC"/>
    <dbReference type="OrthoDB" id="9909019at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883:SF301">
        <property type="entry name" value="PALMITOYLTRANSFERASE ZDHHC12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883">
        <property type="entry name" value="ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0564">Palmitate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="459"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="492"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="11">
        <location>
            <begin position="411"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG96875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="628" mass="76355" checksum="98FD413142270E92" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWF0</accession>
    <name>A0A1J1GWF0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00446400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529686.1">
        <property type="nucleotide sequence ID" value="XM_028673211.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWF0"/>
    <dbReference type="GeneID" id="39732997"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00446400"/>
    <dbReference type="OMA" id="KKLECQG"/>
    <dbReference type="OrthoDB" id="377966at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013062966" evidence="2">
        <location>
            <begin position="20"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="819"/>
            <end position="842"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="845" mass="102651" checksum="A686F7992DA2AE8F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWF5</accession>
    <name>A0A1J1GWF5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00283400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528445.1">
        <property type="nucleotide sequence ID" value="XM_028671831.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWF5"/>
    <dbReference type="GeneID" id="39731367"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00283400"/>
    <dbReference type="OrthoDB" id="372280at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="450" mass="54129" checksum="069904C81EA74166" modified="2017-02-15" version="1">MKLLFFIYNFIYLMNTYNYECYLISKKNSTYVNKINIKILGSVYPESFLTHSKNIIYNSLKITRKKKNRKSMQIYLINKSKLKKQNAVLKNKSFKHGHFLKKNRCTNDMSEDKINKFDTKRKVHKKKEETYIQNNDKNVSLTKKKKKKKRSKKENKNQNEWLLNYIKKNKINKEENIPDDLKDEHHDFLKYFKMQDNTLTSELNPEQSKEIIKSDYFKNLMAELNLKEDEILSMLKRNEKDVTYLINKNLSIEEIEKKAKNEDVQNEKLFVTFMDNRSLKVGNFVNFKKIGRKYKDIIREVINYFLTKKKDYIDMMKNIENANEIDNYIILLKENVFFKDFNNEILKEIVKKTIIMGYLNQVFSNDIQNFEWNKNIEKCIMSSINNKYKVKEIIYSNNSININIEGMKNNDIDSDEYDEIENSIRSSIEEYQKINNLKILSYFNIFITIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWI4</accession>
    <name>A0A1J1GWI4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00441200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529634.1">
        <property type="nucleotide sequence ID" value="XM_028673152.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWI4"/>
    <dbReference type="GeneID" id="39732945"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00441200"/>
    <dbReference type="OMA" id="TCICYAM"/>
    <dbReference type="OrthoDB" id="336859at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="223" mass="25735" checksum="0ABEDF3B796B0441" modified="2017-02-15" version="1">MDDEESYESGISSDDSLSVAKKKYVTNSEGCCYNFSNEIFKLSVISYYFWIGFCYLIGSVVFSTGYNSSSLRIQDQIVCAASSNVYLFSILWFFIGVISIVTCIGYSLSIDEENNKIYSKNSPLFIYILGILCKTIPTIVRVIHIFNLFQLYLITLDIMFLPECNSFYVRFILFIIHILWWLIVFFGIISRKKIFLPPHLYKPLTNDTGFVVYINNLLHSFGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWJ4</accession>
    <name>A0A1J1GWJ4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tetratricopeptide repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00439300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529615.1">
        <property type="nucleotide sequence ID" value="XM_028673131.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732926"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00439300"/>
    <dbReference type="OMA" id="KCKDVKC"/>
    <dbReference type="OrthoDB" id="392925at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11980">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="430"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1136"/>
            <end position="1213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1136"/>
            <end position="1208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1572" mass="186398" checksum="3C4C814F2C3E0F8F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWX1</accession>
    <name>A0A1J1GWX1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glutamine-dependent NAD(+) synthetase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">NADSYN</name>
        <name evidence="8" type="ORF">PGAL8A_00439500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; NAD(+) biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529617.1">
        <property type="nucleotide sequence ID" value="XM_028673134.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWX1"/>
    <dbReference type="GeneID" id="39732928"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00439500"/>
    <dbReference type="OMA" id="TSQEVCN"/>
    <dbReference type="OrthoDB" id="2020662at2759"/>
    <dbReference type="UniPathway" id="UPA00253"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003952">
        <property type="term" value="F:NAD+ synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD+ biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00553">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014445">
        <property type="entry name" value="Gln-dep_NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003694">
        <property type="entry name" value="NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23090:SF9">
        <property type="entry name" value="GLUTAMINE-DEPENDENT NAD(+) SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23090">
        <property type="entry name" value="NH 3 /GLUTAMINE-DEPENDENT NAD + SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006630">
        <property type="entry name" value="NADS_GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="Carbon-nitrogen hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="738"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="domain" description="NAD/GMP synthase" evidence="7">
        <location>
            <begin position="456"/>
            <end position="729"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="816" mass="95741" checksum="2A972997191DB18C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXC9</accession>
    <name>A0A1J1GXC9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">RNA-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00468900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529911.1">
        <property type="nucleotide sequence ID" value="XM_028673461.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXC9"/>
    <dbReference type="GeneID" id="39733222"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00468900"/>
    <dbReference type="OMA" id="FRHEMPR"/>
    <dbReference type="OrthoDB" id="10259600at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071006">
        <property type="term" value="C:U2-type catalytic step 1 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071007">
        <property type="term" value="C:U2-type catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036002">
        <property type="term" value="F:pre-mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017070">
        <property type="term" value="F:U6 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12292">
        <property type="entry name" value="RRM2_La_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039171">
        <property type="entry name" value="Cwc2/Slt11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048995">
        <property type="entry name" value="STL11/RBM22-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14089">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR RBM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14089:SF6">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR RBM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21369">
        <property type="entry name" value="STL11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 6" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="8">
        <location>
            <begin position="153"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="222"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="153"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG97108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="355" mass="41592" checksum="B457A696213C07EA" modified="2017-02-15" version="1">MDRYGHNVRTDVKKQGYENSDLPILCETCLGENPYVRLIREENGKECKICKNAFTLFRWKPGQKARYKQTVICGMCAKVKNVCQTCLFDLEYNLPVQVRDKFIENAITLPENETNRNFFLEQMEKNMSTSYNKANHINIDLSKLKRYDPYFKRNMARVCSFWRNNSCNRGSECPYLHKEIHLDKSLYNQNIKNRYTGENDVLAEKILKKYNKENEGENFMANTICIHGISESVNQVNIKECFKKYGEIKSIKMIPKDCKMFISYKNYSSAKKASEEYKDGLELNGCNLTVLLQEEIYNSNIKNQGNMNFLSNQKNYQNINVPYMYYPFYSNNLNTLSPNATPYSSMIPSEAEQRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXD3</accession>
    <name>A0A1J1GXD3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA-binding protein Nova-1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00286900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528480.1">
        <property type="nucleotide sequence ID" value="XM_028671871.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXD3"/>
    <dbReference type="GeneID" id="39731402"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00286900"/>
    <dbReference type="OMA" id="SIAKEPH"/>
    <dbReference type="OrthoDB" id="441329at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd22435">
        <property type="entry name" value="KH-I_NOVA_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09031">
        <property type="entry name" value="KH-I_NOVA_rpt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047275">
        <property type="entry name" value="KH-I_NOVA_rpt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047274">
        <property type="entry name" value="KH-I_NOVA_rpt3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="K Homology" evidence="3">
        <location>
            <begin position="16"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="3">
        <location>
            <begin position="106"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="3">
        <location>
            <begin position="246"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="334" mass="37199" checksum="0F7982503C0AF1A8" modified="2017-02-15" version="1">MEEKNQSEKRNKSNGQLCFVKMLVNNLVAGSVIGKNGSIITSIENKTGCNLKLSPNNSYFPNTQERVLVLCGKQEQINSALLIILDKIRQIASHHFYDKQNPNATPKYTCRIVVPKSAVSAIIGKGGQQIKQLQDSTGSKIQISSREDGLNERIITIIGTFESISDTALKVANSIQSDPNLKDLLNVIYNKESNYNSRALTHNFINQLHLNGYVIPQQYGVFQHDQYMDVGMMNSLMRHSRDLFNLPCEISIQIPDEFIGSVIGKNGSRLTNIMNSTGAQIRISRKGELIPGTTDRKVRIIGTVAAVHAAHVLLLQRLESVYMQIRTMQVKCDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXF1</accession>
    <name>A0A1J1GXF1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00471300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529935.1">
        <property type="nucleotide sequence ID" value="XM_028673487.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXF1"/>
    <dbReference type="GeneID" id="39733246"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00471300"/>
    <dbReference type="OMA" id="WHELRIK"/>
    <dbReference type="OrthoDB" id="378113at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="71"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="466"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="614"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="648" mass="77906" checksum="2CE73D6FEBA050BA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXG5</accession>
    <name>A0A1J1GXG5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00290800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528512.1">
        <property type="nucleotide sequence ID" value="XM_028671906.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731441"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00290800"/>
    <dbReference type="OMA" id="PPKGMTP"/>
    <dbReference type="OrthoDB" id="372685at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="610"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="698"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="766"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="700"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="766"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="776"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="810"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="917"/>
            <end position="1056"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1370" mass="160808" checksum="2C060D4EC7ABE413" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXG6</accession>
    <name>A0A1J1GXG6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Rhoptry neck protein 3, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RON3</name>
        <name evidence="4" type="ORF">PGAL8A_00473100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529951.1">
        <property type="nucleotide sequence ID" value="XM_028673505.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733264"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00473100"/>
    <dbReference type="OMA" id="FNIRHIY"/>
    <dbReference type="OrthoDB" id="371154at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013062998" evidence="3">
        <location>
            <begin position="21"/>
            <end position="2158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="271"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1649"/>
            <end position="1711"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1728"/>
            <end position="1753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1686"/>
            <end position="1703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1728"/>
            <end position="1739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1740"/>
            <end position="1753"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2158" mass="256371" checksum="9D3A97D8AEE1DA79" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXH2</accession>
    <name>A0A1J1GXH2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NIMA related kinase 3, putative</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">NEK3</name>
        <name evidence="2" type="ORF">PGAL8A_00320200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528797.1">
        <property type="nucleotide sequence ID" value="XM_028672224.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXH2"/>
    <dbReference type="GeneID" id="39731735"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00320200"/>
    <dbReference type="OMA" id="MNYGYKF"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053235">
        <property type="entry name" value="Ser_Thr_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24361">
        <property type="entry name" value="MITOGEN-ACTIVATED KINASE KINASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="26"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="295" mass="33658" checksum="8A3AFAFBEC17E9FF" modified="2017-02-15" version="1">MLSLLLPSNDSAEKHNLYTNYGYTFETVLDILTSNSELHVIKSIKTGEIFISKVYDIYGISENDLSKYMNELYIMKKLENCENVVKIVDFIKKNDSLSLILEFCSQGDLHSDILRRKLNNEIYTESEIFNILNQILNGLSSIHKSGIIHGDLKSTNIFIKDDKIKIGDFGISQIGTNNNLGTLNFLSYESIKFRRTNKLSDLFQVGCILFELATLSSPFSAKNMSEMISLFEDKNYKNYIVKSISSFYSKKLVNIISKLLSLNTLERLEAITNYNLNKCKNTNLEVLNRIECIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXI9</accession>
    <name>A0A1J1GXI9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00475100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529975.1">
        <property type="nucleotide sequence ID" value="XM_028673531.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXI9"/>
    <dbReference type="GeneID" id="39733284"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00475100"/>
    <dbReference type="OMA" id="ENMAYRI"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="401" mass="47507" checksum="F580ABCB0BE9BA2B" modified="2017-02-15" version="1">MNILKAFNFYIILLVPYFIIYIFDFRLLPKSLKHILQINYHGMKLISKRNLAESVPHVSAFYSKTTYDKTFIEKDIFITKFPYSEYVLSQELFNKVYKENYNIEEATDDMEAMLEKINSRFHFEGISLPLPEMLNIINRMIERTLEFPLESPETRENLFKRILELEREATEELLKSLITGDEEVKIDNRDNMVKILGIVRRKLIILNIRLLDNVVTKIATRISQSVESAIKAYNERFKNPPWKNEEYVRLYSKLQYDTLENLLNIICDASYYQTAIDVYCDSKLIMETINGFSRKYNILLSYPQLRNMYFRVKECIKLVSLEPISESTISNILKIYGLEKDLVYEISMQILNSDVQEDEINYTYMTKAKIDYLLETENITLLEDVENMAYRIKSYVLDIIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXZ9</accession>
    <name>A0A1J1GXZ9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NLI interacting factor-like phosphatase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">NIF1</name>
        <name evidence="3" type="ORF">PGAL8A_00500900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530237.1">
        <property type="nucleotide sequence ID" value="XM_028673823.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733542"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00500900"/>
    <dbReference type="OMA" id="KFCEDNC"/>
    <dbReference type="OrthoDB" id="277011at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000093">
        <property type="entry name" value="NLI interacting factor-like phosphatase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011948">
        <property type="entry name" value="Dullard_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02251">
        <property type="entry name" value="HIF-SF_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="2">
        <location>
            <begin position="1139"/>
            <end position="1297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="511"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="858"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="531"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="580"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="648"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="858"/>
            <end position="881"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1316" mass="156858" checksum="3CD35EDA079E4E40" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY05</accession>
    <name>A0A1J1GY05_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">P-type sodium-transporting ATPase4</fullName>
            <ecNumber evidence="12">7.2.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">ATP4</name>
        <name evidence="19" type="ORF">PGAL8A_00310000</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>Na(+)(in) + ATP + H2O = Na(+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.3"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:14634"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.3" evidence="12"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528696.1">
        <property type="nucleotide sequence ID" value="XM_028672111.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY05"/>
    <dbReference type="GeneID" id="39731633"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00310000"/>
    <dbReference type="OMA" id="FNRNPWM"/>
    <dbReference type="OrthoDB" id="116380at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005391">
        <property type="term" value="F:P-type sodium:potassium-exchanging transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030007">
        <property type="term" value="P:intracellular potassium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006883">
        <property type="term" value="P:intracellular sodium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990573">
        <property type="term" value="P:potassium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036376">
        <property type="term" value="P:sodium ion export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000001">
        <property type="entry name" value="Phospholipid-transporting ATPase IC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000083">
        <property type="entry name" value="Sodium/potassium-transporting ATPase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050510">
        <property type="entry name" value="Cation_transp_ATPase_P-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294:SF20">
        <property type="entry name" value="P-TYPE ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294">
        <property type="entry name" value="SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="19" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0915">Sodium</keyword>
    <keyword evidence="11" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="183"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="367"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="403"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="931"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1004"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1209"/>
            <end position="1231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="1237"/>
            <end position="1258"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="18">
        <location>
            <begin position="128"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="10"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00035029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00067200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="CRG95888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1272" mass="141152" checksum="956C05602B7A310C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYD6</accession>
    <name>A0A1J1GYD6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RanBP2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00513700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530365.1">
        <property type="nucleotide sequence ID" value="XM_028673964.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYD6"/>
    <dbReference type="GeneID" id="39733670"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00513700"/>
    <dbReference type="OMA" id="CTQKKIC"/>
    <dbReference type="OrthoDB" id="386953at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RanBP2-type" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="42"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="172"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="45"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="70"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="99"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="213" mass="24068" checksum="D2D1C0F0B4E3EF4B" modified="2017-02-15" version="1">MSNAWRCEACLVMNSEDAYECVCCMQKRNINIEDNANTATVTSSTIDSNNNDNINNSEKKKNNNNNKKLTNNEKAKSSEESITKNKNTKVKKNATNILKDTKKKEKNNVNENVSKLEGGGFMPSVKPADNHESSKSIFLTGIDNTSTPIVTTTSNKQKKELKNNLEEKNKVMEKNKVIEKNKEKKKIESNEKGSNKRIQPARKCTQKKICYKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYI5</accession>
    <name>A0A1J1GYI5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Acetyl-CoA transporter, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00495400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530177.1">
        <property type="nucleotide sequence ID" value="XM_028673757.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYI5"/>
    <dbReference type="GeneID" id="39733487"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00495400"/>
    <dbReference type="OMA" id="RRKSWIM"/>
    <dbReference type="OrthoDB" id="6415790at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008521">
        <property type="term" value="F:acetyl-CoA transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035348">
        <property type="term" value="P:acetyl-CoA transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024371">
        <property type="entry name" value="AcetylCoA_trans_1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004752">
        <property type="entry name" value="AmpG_permease/AT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12778:SF9">
        <property type="entry name" value="ACETYL-COENZYME A TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12778">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 33 ACETYL-COA TRANSPORTER -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13000">
        <property type="entry name" value="Acatn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="212"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="349"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="379"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="417"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="460"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="498"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="535" mass="63104" checksum="27BB3F4AF91A5CB8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYI9</accession>
    <name>A0A1J1GYI9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Macro domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00510600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530334.1">
        <property type="nucleotide sequence ID" value="XM_028673930.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYI9"/>
    <dbReference type="GeneID" id="39733639"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00510600"/>
    <dbReference type="OMA" id="IMPYFWQ"/>
    <dbReference type="OrthoDB" id="6133115at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="entry name" value="Leucine Aminopeptidase, subunit E, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002589">
        <property type="entry name" value="Macro_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01661">
        <property type="entry name" value="Macro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="Macro domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51154">
        <property type="entry name" value="MACRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Macro" evidence="1">
        <location>
            <begin position="97"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="464" mass="54358" checksum="D7236AEFCC12FF2B" modified="2017-02-15" version="1">MKISKWIKILSFDKRNFGSSYLNKKLKLINDRALKYHIDYIRSLDILEGKNRSVMKEIFPNKKSEINDLFFKRESNEDEKDEEDLLNIDLTKNKYHYEMKNMLLNEFGVIKIIHNDIIEEESDCMLIPMVSNFIPLSGFGAYILQKGGRELVKEIFTSIKNLIKKRIEILNEHKEEYLSTSTTMNNEKGFKELVENSKTLQTGDLILTKPHNVSDKVKLLAFLIMPYFWQGNCYISANKLRYSFSNALRQLNELCVSSIILPNIASGIYGYTPNSSSNILIEESIESLLQLNNTVPIYNLNSISFIDKDLNTCKIFSEALEEVSRNYLPHKKVMPAPKYWNTVNRRLLEIPSNVVYFCRRQNKISFKKYHGIIRRKYQNYYSNIRPFKWRASRVVEPNPFLVYKNSGEPSSYQYDYKPYYYKGITHTLYPINKKGLINIRIGNKGKLQALKNISNISLETKPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYJ8</accession>
    <name>A0A1J1GYJ8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ig-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00489200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530115.1">
        <property type="nucleotide sequence ID" value="XM_028673687.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733425"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00489200"/>
    <dbReference type="OrthoDB" id="392334at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007110">
        <property type="entry name" value="Ig-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31765">
        <property type="entry name" value="PROTEIN CBG12783"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31765:SF3">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50835">
        <property type="entry name" value="IG_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ig-like" evidence="2">
        <location>
            <begin position="129"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="619"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="739"/>
            <end position="770"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1407" mass="168268" checksum="BFF5A35C1C4E2F7F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYL7</accession>
    <name>A0A1J1GYL7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RNA-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00524200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530467.1">
        <property type="nucleotide sequence ID" value="XM_028674078.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYL7"/>
    <dbReference type="GeneID" id="39733775"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00524200"/>
    <dbReference type="OMA" id="DQMPYNI"/>
    <dbReference type="OrthoDB" id="412781at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050437">
        <property type="entry name" value="Ribos_protein_bS1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004170">
        <property type="entry name" value="WWE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10724">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10724:SF10">
        <property type="entry name" value="S1 RNA-BINDING DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50918">
        <property type="entry name" value="WWE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="3">
        <location>
            <begin position="612"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="3">
        <location>
            <begin position="779"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="domain" description="WWE" evidence="4">
        <location>
            <begin position="1025"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="298"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="904"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="88"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="304"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="904"/>
            <end position="930"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1105" mass="132093" checksum="756F392BEA0E0875" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYY9</accession>
    <name>A0A1J1GYY9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Septum formation protein MAF homologue, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00510000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530328.1">
        <property type="nucleotide sequence ID" value="XM_028673924.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYY9"/>
    <dbReference type="GeneID" id="39733633"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00510000"/>
    <dbReference type="OMA" id="RDQRMHK"/>
    <dbReference type="OrthoDB" id="10267058at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047429">
        <property type="term" value="F:nucleoside triphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00555">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00528">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003697">
        <property type="entry name" value="Maf-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00172">
        <property type="entry name" value="maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43213">
        <property type="entry name" value="BIFUNCTIONAL DTTP/UTP PYROPHOSPHATASE/METHYLTRANSFERASE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43213:SF5">
        <property type="entry name" value="BIFUNCTIONAL DTTP_UTP PYROPHOSPHATASE_METHYLTRANSFERASE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02545">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="ITPase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="265" mass="30954" checksum="68F10329C538BD8E" modified="2017-02-15" version="1">MKEFSHIIGLGDIFQNEKKCWVLLASKSPRRMELMRLIGIKNLYICDSKFEENLDKNKFSSAEDYVKENALNKGLKVVEHIWFNNKNNENTKEDINHTEKDETNKDERSINEVNKIEINKYEVKNLYSNYNPIPYIIISCDTIVTLKNEIIEKPLNKKHAYEILKKLSSNVHTVYTAVCIFVYKTKTPITFVEKTDVHFDQLLEKDILEYINLKEPYDKAGAYSIQGIGSQFIKKIDGCYYNVMGLPIHKLSKTLTKLHLEKNFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ00</accession>
    <name>A0A1J1GZ00_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">AP-4 complex subunit mu, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00346100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the adaptor complexes medium subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529048.1">
        <property type="nucleotide sequence ID" value="XM_028672502.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ00"/>
    <dbReference type="GeneID" id="39731991"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00346100"/>
    <dbReference type="OMA" id="DYGYIQN"/>
    <dbReference type="OrthoDB" id="10259133at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030131">
        <property type="term" value="C:clathrin adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09253">
        <property type="entry name" value="AP-4_Mu4_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14838">
        <property type="entry name" value="AP4_Mu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000002">
        <property type="entry name" value="AP-2 complex subunit mu, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1170">
        <property type="entry name" value="Mu homology domain, subdomain B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050431">
        <property type="entry name" value="Adaptor_comp_med_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001392">
        <property type="entry name" value="Clathrin_mu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10529">
        <property type="entry name" value="AP COMPLEX SUBUNIT MU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00928">
        <property type="entry name" value="Adap_comp_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005992">
        <property type="entry name" value="Clathrin_mu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00314">
        <property type="entry name" value="CLATHRINADPT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MHD" evidence="6">
        <location>
            <begin position="175"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR005992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="434" mass="51061" checksum="FD55845F34EA7D9A" modified="2017-02-15" version="1">MVISQFYILSPRGDTIINRDFRGDITKSSAEVFFRNVKLYKGDAPPLFYLNGINFTYLKNNSLYFVLTSLFNISPSYLIELLNRLLKIFKDFCGQITEEIIRMNFILIYEIIDEVIDYGYLQNSNTEYIRNLIHNEITTTNANKKFANLSNFSIKNSNTLPSNASQKPIQINDKKNEIFIDIVEKINLIMNSKSEIIYSYIDGVIQIKSYLLGNPYIKIAFNDDLYIKNIHNDTSNNIIIDDCNFNHLVNLSQFEKEKILSLYQPDGECVLMNYRINNNFKAPFKIFANIIYNQNHTVELNIRIRLDIPSQYTCTNVFVNCNLCKHITNVHINLNTNTELYSAQYLSNEHKLLWTIKKFKGESEYNIRSKITLAPNYVYSKRDFGPIYILFEIPMFNLSKLRIKYLRIIENYKSSNTHRWVRYITQSSSYVYRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ98</accession>
    <name>A0A1J1GZ98_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00022400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530590.1">
        <property type="nucleotide sequence ID" value="XM_028674215.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ98"/>
    <dbReference type="GeneID" id="39728747"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00022400"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013221415" evidence="1">
        <location>
            <begin position="23"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="101" mass="12140" checksum="209DF6B04498841E" modified="2017-02-15" version="1">MKIFTLCLNIFTFFILTWKIHCFYNYDSSRSLINKDTMQMKNKLKHERLLAEVGVLEEKQTAELEMVPFYKETNEISNKSKDKILNDYWNNNSHVDELQQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZA9</accession>
    <name>A0A1J1GZA9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Small ribosomal subunit nuclear export protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00514200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CBF/MAK21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530370.1">
        <property type="nucleotide sequence ID" value="XM_028673970.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZA9"/>
    <dbReference type="GeneID" id="39733675"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00514200"/>
    <dbReference type="OrthoDB" id="378151at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030692">
        <property type="term" value="C:Noc4p-Nop14p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005612">
        <property type="entry name" value="CCAAT-binding_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027193">
        <property type="entry name" value="Noc4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12455">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12455:SF0">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03914">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCAAT-binding factor" evidence="4">
        <location>
            <begin position="830"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="570"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="675"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="129"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="574"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="588"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="610"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="623"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="683"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="695"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="778"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="803"/>
            <end position="821"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1148" mass="137516" checksum="7C00CC411BC34133" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZD1</accession>
    <name>A0A1J1GZD1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DNA primase large subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00423700</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="9">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the eukaryotic-type primase large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529461.1">
        <property type="nucleotide sequence ID" value="XM_028672960.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZD1"/>
    <dbReference type="GeneID" id="39732769"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00423700"/>
    <dbReference type="OMA" id="RINYKPW"/>
    <dbReference type="OrthoDB" id="421393at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005658">
        <property type="term" value="C:alpha DNA polymerase:primase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07322">
        <property type="entry name" value="PriL_PriS_Eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058560">
        <property type="entry name" value="DNA_primase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016558">
        <property type="entry name" value="DNA_primase_lsu_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007238">
        <property type="entry name" value="DNA_primase_lsu_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10537">
        <property type="entry name" value="DNA PRIMASE LARGE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10537:SF3">
        <property type="entry name" value="DNA PRIMASE LARGE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04104">
        <property type="entry name" value="DNA_primase_lrg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26466">
        <property type="entry name" value="DNA_primase_lrg_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009449">
        <property type="entry name" value="DNA_primase_large_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9 10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 9" id="KW-0639">Primosome</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA primase large subunit C-terminal" evidence="11">
        <location>
            <begin position="354"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="362"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="438"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="456"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="496"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR009449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR009449-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG96657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="540" mass="64164" checksum="A0551823FB124230" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZU6</accession>
    <name>A0A1J1GZU6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00057700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530939.1">
        <property type="nucleotide sequence ID" value="XM_028674603.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZU6"/>
    <dbReference type="GeneID" id="39729102"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00057700"/>
    <dbReference type="OMA" id="YENRCPL"/>
    <dbReference type="OrthoDB" id="416496at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052356">
        <property type="entry name" value="Thiol_S-MT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45036:SF1">
        <property type="entry name" value="METHYLTRANSFERASE LIKE 7A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45036">
        <property type="entry name" value="METHYLTRANSFERASE LIKE 7B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransferase type 11" evidence="2">
        <location>
            <begin position="87"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="310" mass="36453" checksum="45949D646E8F7F0C" modified="2017-02-15" version="1">MFTFSSFKKLLLGVTVANGSVILGCFYIYKKNRPLNVMLDEPTENFRIKIFDALAKNYDEKNDFIEKITSINKYKKKNFRKARGVVLEIGAGSGRNFAYLNKIDILICVEKSENMCKELKKKVEKIKPPYPVYIINNDIKNNIFKPEVFDSVISSFTLCSLEYLDESLKNIYQALKNNGKFYLVERGIIYNKFIRYILEKLNLYPNYKMPWEYGYYENRYPLEILKKNDFSIIFKLVKNAGSVYILIAKKYISSDMNSGINNDQKVKKINSEVQDKINNNIHMKERNIDINNIISDPQKVPIYYYYKNDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZV0</accession>
    <name>A0A1J1GZV0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">serine--tRNA ligase</fullName>
            <ecNumber evidence="4">6.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Seryl-tRNA synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Seryl-tRNA(Ser/Sec) synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">PGAL8A_00530600</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>tRNA(Sec) + L-serine + ATP = L-seryl-tRNA(Sec) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:42580"/>
            <dbReference type="Rhea" id="RHEA-COMP:9742"/>
            <dbReference type="Rhea" id="RHEA-COMP:10128"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>tRNA(Ser) + L-serine + ATP = L-seryl-tRNA(Ser) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12292"/>
            <dbReference type="Rhea" id="RHEA-COMP:9669"/>
            <dbReference type="Rhea" id="RHEA-COMP:9703"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; L-seryl-tRNA(Sec) from L-serine and tRNA(Sec): step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.11" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530530.1">
        <property type="nucleotide sequence ID" value="XM_028674148.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZV0"/>
    <dbReference type="GeneID" id="39733839"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00530600"/>
    <dbReference type="OrthoDB" id="10264585at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004828">
        <property type="term" value="F:serine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006434">
        <property type="term" value="P:seryl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002317">
        <property type="entry name" value="Ser-tRNA-ligase_type_1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00414">
        <property type="entry name" value="serS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43697:SF1">
        <property type="entry name" value="SERINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43697">
        <property type="entry name" value="SERYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00981">
        <property type="entry name" value="TRNASYNTHSER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 18" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="16" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013380399" description="serine--tRNA ligase" evidence="16">
        <location>
            <begin position="20"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="17">
        <location>
            <begin position="308"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="88"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="CRG97729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="571" mass="66986" checksum="EA93EB1599572E25" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H011</accession>
    <name>A0A1J1H011_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00050800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530870.1">
        <property type="nucleotide sequence ID" value="XM_028674526.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H011"/>
    <dbReference type="GeneID" id="39729033"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00050800"/>
    <dbReference type="OMA" id="KPRHMYV"/>
    <dbReference type="OrthoDB" id="387618at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="209" mass="25143" checksum="0478D9A35A5ECA2B" modified="2017-02-15" version="1">MKVNNFKNKKLKEKQLTENLKPKKTKKLKNELTLRNNEKYKQKKDKVKYKKKSLNLSKHDDTSYNVRKEEKIKKDKINSVKTITSKKINKKEEKESSKLRIYTDISESEDLDEELCDDDNLFMPSKSKYNKRKSLINETSKQKKKKNLKKKQCAAKYLKLNEYNEEYEKELLSYAINGFYKYVNFLKNYKNSITVENQMDNKKPKHLYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H068</accession>
    <name>A0A1J1H068_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00064700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028531005.1">
        <property type="nucleotide sequence ID" value="XM_028674676.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H068"/>
    <dbReference type="GeneID" id="39729172"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00064700"/>
    <dbReference type="OrthoDB" id="440020at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="612"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="805"/>
            <end position="848"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="858" mass="101739" checksum="CEC7562B5DBC7F05" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0D7</accession>
    <name>A0A1J1H0D7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">40S ribosomal protein S29, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00045800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uS14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530824.1">
        <property type="nucleotide sequence ID" value="XM_028674475.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0D7"/>
    <dbReference type="GeneID" id="39728983"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00045800"/>
    <dbReference type="OMA" id="HCFREIA"/>
    <dbReference type="OrthoDB" id="10252683at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.830.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.10">
        <property type="entry name" value="30s Ribosomal Protein S14, Chain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001209">
        <property type="entry name" value="Ribosomal_uS14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018271">
        <property type="entry name" value="Ribosomal_uS14_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039744">
        <property type="entry name" value="RIbosomal_uS14_euk_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043140">
        <property type="entry name" value="Ribosomal_uS14_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004424">
        <property type="entry name" value="PRK05766.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12010">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12010:SF2">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00253">
        <property type="entry name" value="Ribosomal_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00527">
        <property type="entry name" value="RIBOSOMAL_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG98027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="54" mass="6430" checksum="82B862E801FEAC64" modified="2017-02-15" version="1">MGCIQNVHPKKYGQGSRQCRVCSNKHAIIRKYNINICRQCFRERANIIGFKKYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0J7</accession>
    <name>A0A1J1H0J7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Armadillo repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00438600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529608.1">
        <property type="nucleotide sequence ID" value="XM_028673124.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732919"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00438600"/>
    <dbReference type="OrthoDB" id="27832at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035145">
        <property type="term" value="C:exon-exon junction complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039762">
        <property type="entry name" value="Nmd2/UPF2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12839">
        <property type="entry name" value="NONSENSE-MEDIATED MRNA DECAY PROTEIN 2 UP-FRAMESHIFT SUPPRESSOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12839:SF7">
        <property type="entry name" value="REGULATOR OF NONSENSE TRANSCRIPTS 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1041"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="191"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1305"/>
            <end position="1332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1041"/>
            <end position="1059"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1383" mass="165542" checksum="899AFD8AF782D4F7" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1I4</accession>
    <name>A0A1J1H1I4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00474400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000089">
        <property type="protein sequence ID" value="CRG97165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529968.1">
        <property type="nucleotide sequence ID" value="XM_028673524.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1I4"/>
    <dbReference type="GeneID" id="39733277"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00474400"/>
    <dbReference type="OMA" id="MENNITH"/>
    <dbReference type="OrthoDB" id="348930at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="724"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="612"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="331"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="387"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="453"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="503"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="612"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1018"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1018" mass="114903" checksum="84BD4B49D9EBCD13" modified="2017-02-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1S9</accession>
    <name>A0A1J1H1S9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cell division cycle protein 20 homolog, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CDC20</name>
        <name evidence="7" type="ORF">PGAL8A_00485700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat CDC20/Fizzy family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530080.1">
        <property type="nucleotide sequence ID" value="XM_028673649.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1S9"/>
    <dbReference type="GeneID" id="39733390"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00485700"/>
    <dbReference type="OMA" id="FHFTKHK"/>
    <dbReference type="OrthoDB" id="10263272at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010997">
        <property type="term" value="F:anaphase-promoting complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990757">
        <property type="term" value="F:ubiquitin ligase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905786">
        <property type="term" value="P:positive regulation of anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033010">
        <property type="entry name" value="Cdc20/Fizzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056150">
        <property type="entry name" value="WD40_CDC20-Fz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918">
        <property type="entry name" value="CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19918:SF1">
        <property type="entry name" value="FIZZY-RELATED PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24807">
        <property type="entry name" value="WD40_CDC20-Fz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="CDC20/Fizzy WD40" evidence="6">
        <location>
            <begin position="205"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="347"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="477"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF24807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="531" mass="62486" checksum="C8ADD77640FF8EBB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3H4</accession>
    <name>A0A1J1H3H4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rhoptry-associated membrane antigen, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RAMA</name>
        <name evidence="3" type="ORF">PGAL8A_00047400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530836.1">
        <property type="nucleotide sequence ID" value="XM_028674489.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3H4"/>
    <dbReference type="GeneID" id="39728999"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00047400"/>
    <dbReference type="OMA" id="NEHEESF"/>
    <dbReference type="OrthoDB" id="387534at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009618960" evidence="2">
        <location>
            <begin position="17"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="437"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="437"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="456"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="712" mass="84753" checksum="43B19B41A22E60B8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKT4</accession>
    <name>A0A1J1GKT4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00068900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG92985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525807.1">
        <property type="nucleotide sequence ID" value="XM_028672310.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKT4"/>
    <dbReference type="GeneID" id="39729214"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00068900"/>
    <dbReference type="OrthoDB" id="371881at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG92985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="92" mass="10975" checksum="CCB1D75B78D0F4B4" modified="2017-02-15" version="1">MKYTCFEEIYSEYGINEEVSFSSDETADTTLLKGEQCMKQNKWENKEIPISKNFKIKKRNSNLHEELSIFDDFKIILYGCIGIRTYKMFCYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKY2</accession>
    <name>A0A1J1GKY2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00068300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG92979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525801.1">
        <property type="nucleotide sequence ID" value="XM_028671643.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKY2"/>
    <dbReference type="GeneID" id="39729208"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00068300"/>
    <dbReference type="OMA" id="RIGHEDK"/>
    <dbReference type="OrthoDB" id="387696at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="105"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="123"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="421"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="451"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="462"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG92979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="633" mass="76224" checksum="6C45AF543D82CCB1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL96</accession>
    <name>A0A1J1GL96_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00081200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525930.1">
        <property type="nucleotide sequence ID" value="XM_028670577.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL96"/>
    <dbReference type="GeneID" id="39729336"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00081200"/>
    <dbReference type="OrthoDB" id="391514at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="341"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="352"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="505" mass="58813" checksum="55730A16E435A0F7" modified="2017-02-15" version="1">MVNMKSIHQVNNIGDSFMYPKNSVDRTDTINRRKDEYKMSMNFHKKTEESNKRTKNNYEYLDSTHLEMLDLNKDIQNILPKPIKPSINLESLCKETSATLKNNSTLKSIKKVEEQQKNIKHFYELGSPQIIGTYIQPLNKNQNNSVKDDNLENNSFPLAPSSPFFQPPKFSTKLTQPTNQFLSTNINKSTNIYGLPSYLIPENKPHRLNVTVVPNKDKDILEKEAKHLKLLLDNSSQGIVNSTPDYQKIIDSNLSNNNDKESDFSFGKHENLENMQDEYSYENITDNNYNDSLINEFYDTNNCTCYSQMNELINHSNYNNENDFHLLSNEQLKKVNKELNQPKDNVNNLNKSNEKEKDIKNNSLSKKTESIKKKESISLSKKHEPSICFKNPKTYINIRLGRPKKLYITNSSDPIDKKLRDWHNTHNSQIGWKKNRRGVYTFGKTEVVLNLAHDKIIVKKINGKDIKDNLLTVEKFVSLNELYELQQEENDNELKIKNKKNSQFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLB3</accession>
    <name>A0A1J1GLB3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">CDGSH iron-sulfur domain-containing protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00090200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526020.1">
        <property type="nucleotide sequence ID" value="XM_028671577.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLB3"/>
    <dbReference type="GeneID" id="39729426"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00090200"/>
    <dbReference type="OrthoDB" id="449252at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.90">
        <property type="entry name" value="CDGSH iron-sulfur domain, mitoNEET-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018967">
        <property type="entry name" value="FeS-contain_CDGSH-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042216">
        <property type="entry name" value="MitoNEET_CISD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09360">
        <property type="entry name" value="zf-CDGSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00704">
        <property type="entry name" value="ZnF_CDGSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Iron-binding zinc finger CDGSH type" evidence="6">
        <location>
            <begin position="38"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="88" mass="10364" checksum="056B1DF27B62E5DC" modified="2017-02-15" version="1">MGNKLFKGNNYDILRNKGDILNIRNFKPLHIETFYPPLKKSKKVSVCRCWKSNNFPYCDNTHQKLQQQGIICGPLLLEIRKNNNIYSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLG4</accession>
    <name>A0A1J1GLG4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00096200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526078.1">
        <property type="nucleotide sequence ID" value="XM_028672222.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLG4"/>
    <dbReference type="GeneID" id="39729486"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00096200"/>
    <dbReference type="OrthoDB" id="10249433at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277">
        <property type="entry name" value="ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277:SF197">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_38, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="428"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="661"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="438"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="661"/>
            <end position="771"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="821" mass="97276" checksum="EFAD2EC6D4CA10E3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLP4</accession>
    <name>A0A1J1GLP4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">StAR-related lipid transfer protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00100300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526119.1">
        <property type="nucleotide sequence ID" value="XM_028672677.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLP4"/>
    <dbReference type="GeneID" id="39729527"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00100300"/>
    <dbReference type="OrthoDB" id="370316at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013289303" evidence="1">
        <location>
            <begin position="23"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="507" mass="61411" checksum="77E16EDD88F537DA" modified="2017-02-15" version="1">MILKKKIFLLLIFFFLFNECFCYEKKKEFIKFLDSSSSELSKNKLSFKPFMVNQNAIFNKLFLKNISSYMLDKLEFSKNWKKLDEANKENFNNIHLKEKFFFRIRKENKKNPYAYIPINEDSKKEFNNFEKNNTYKSISYDNIFKNDKIIESSQLKNKEYNTSFKKEINSNNDSSNENNLHRFNEMINKEMINNFKDICNQIYKKTFDLKNSSKVHNSNILTLYKNLLEGKDKKYDLLGYGEMKDVSAYVLNYSLNDIKSIKKWNTNIKRLNYLNISKSTLLKKKSSREMLDVNKYIVNDEKDIENEKKNILYLVNSLPWPFKSHDVIYEVFQNYDESENMFIIVNKSINDLFNKNENFSRINNYENFFCIYPKKKDIFQKGLDYVISLYYNASLPKFIQNNLFSNLFPSLIYNLYSYSQKETIKKKDINHEDKMKLLKHNDLENCEKNDNKKREIQDEKYNEKLDKRNNCYIKKLFKFVFTEKINTIWKAKKNFLKKLFFYLYNLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM41</accession>
    <name>A0A1J1GM41_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00119200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526308.1">
        <property type="nucleotide sequence ID" value="XM_028674704.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM41"/>
    <dbReference type="GeneID" id="39729717"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00119200"/>
    <dbReference type="OMA" id="DHINICY"/>
    <dbReference type="OrthoDB" id="345381at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="192"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="444"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="550"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="98"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="195"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="459"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="559"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="901" mass="107598" checksum="0216E688DD72AD37" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM96</accession>
    <name>A0A1J1GM96_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00118200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526298.1">
        <property type="nucleotide sequence ID" value="XM_028674666.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729707"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00118200"/>
    <dbReference type="OMA" id="KKRESHY"/>
    <dbReference type="OrthoDB" id="378178at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="825"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1265"/>
            <end position="1286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1437"/>
            <end position="1460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1735"/>
            <end position="1791"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1035"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1580"/>
            <end position="1624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="825"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="843"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="857"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1275"/>
            <end position="1286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1451"/>
            <end position="1460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1770"/>
            <end position="1784"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1860" mass="223294" checksum="1151F5FFEEB32D04" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMW7</accession>
    <name>A0A1J1GMW7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nucleolar GTP-binding protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00141400</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the biogenesis of the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
            <location evidence="1 6">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526530.1">
        <property type="nucleotide sequence ID" value="XM_028674950.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMW7"/>
    <dbReference type="GeneID" id="39729938"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00141400"/>
    <dbReference type="OMA" id="EWKNDVM"/>
    <dbReference type="OrthoDB" id="415015at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01897">
        <property type="entry name" value="NOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024926">
        <property type="entry name" value="NOG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041623">
        <property type="entry name" value="NOG1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010674">
        <property type="entry name" value="NOG1_Rossman_fold_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012973">
        <property type="entry name" value="NOG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45759">
        <property type="entry name" value="NUCLEOLAR GTP-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06858">
        <property type="entry name" value="NOG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17835">
        <property type="entry name" value="NOG1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08155">
        <property type="entry name" value="NOGCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038919">
        <property type="entry name" value="NOG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="OBG-type G" evidence="9">
        <location>
            <begin position="172"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="393"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="652"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="558"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="393"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="662"/>
            <end position="682"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR038919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG93708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="682" mass="79392" checksum="568424AA46B1126A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN15</accession>
    <name>A0A1J1GN15_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Histone H2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">H2A</name>
        <name evidence="11" type="ORF">PGAL8A_00146200</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the histone H2A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526578.1">
        <property type="nucleotide sequence ID" value="XM_028675004.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN15"/>
    <dbReference type="GeneID" id="39729986"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00146200"/>
    <dbReference type="OMA" id="CALESQH"/>
    <dbReference type="OrthoDB" id="193243at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00074">
        <property type="entry name" value="HFD_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000009">
        <property type="entry name" value="Histone H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002119">
        <property type="entry name" value="Histone_H2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032454">
        <property type="entry name" value="Histone_H2A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032458">
        <property type="entry name" value="Histone_H2A_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23430">
        <property type="entry name" value="HISTONE H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16211">
        <property type="entry name" value="Histone_H2A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00620">
        <property type="entry name" value="HISTONEH2A"/>
    </dbReference>
    <dbReference type="SMART" id="SM00414">
        <property type="entry name" value="H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00046">
        <property type="entry name" value="HISTONE_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 8" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="9">
        <location>
            <begin position="5"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="Histone H2A C-terminal" evidence="10">
        <location>
            <begin position="92"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG93756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="133" mass="14236" checksum="D57811A2DDA74CF0" modified="2017-02-15" version="1">MSAKGKTGRKKAVKGTSNSAKAGLQFPVGRIGRYLKKGKYAKRVGAGAPVYLAAVLEYLCAEILELAGNAARDNKKSRITPRHIQLAVRNDEELNKFLAGVTFASGGVLPNIHNVLLPKKTQVKTGGTANQEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN94</accession>
    <name>A0A1J1GN94_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA replication licensing factor MCM6</fullName>
            <ecNumber evidence="12">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PGAL8A_00161400</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">Component of the MCM2-7 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="12"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526727.1">
        <property type="nucleotide sequence ID" value="XM_028675169.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN94"/>
    <dbReference type="GeneID" id="39730139"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00161400"/>
    <dbReference type="OMA" id="VQDENMA"/>
    <dbReference type="OrthoDB" id="1744952at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990518">
        <property type="term" value="F:single-stranded 3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902969">
        <property type="term" value="P:mitotic DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17757">
        <property type="entry name" value="MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000003">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000826">
        <property type="entry name" value="Replicative DNA helicase Mcm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.870">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008049">
        <property type="entry name" value="MCM6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041024">
        <property type="entry name" value="Mcm6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF43">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18263">
        <property type="entry name" value="WHD_MCM6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01662">
        <property type="entry name" value="MCMPROTEIN6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 12" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="14">
        <location>
            <begin position="437"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="772"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="779"/>
            <end position="791"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU368064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG93906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="930" mass="106112" checksum="57C44E480B9F4968" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNC5</accession>
    <name>A0A1J1GNC5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Trafficking protein particle complex subunit 6A, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00147100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAPP small subunits family. BET3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526587.1">
        <property type="nucleotide sequence ID" value="XM_028675014.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNC5"/>
    <dbReference type="GeneID" id="39729995"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00147100"/>
    <dbReference type="OMA" id="NFTHYVL"/>
    <dbReference type="OrthoDB" id="941624at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005801">
        <property type="term" value="C:cis-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030008">
        <property type="term" value="C:TRAPP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.20">
        <property type="entry name" value="Trafficking protein particle complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007194">
        <property type="entry name" value="TRAPP_component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037992">
        <property type="entry name" value="TRAPPC6/Trs33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12817:SF0">
        <property type="entry name" value="GEO08327P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12817">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04051">
        <property type="entry name" value="TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="Ligand-binding domain in the NO signalling and Golgi transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="192"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="235" mass="27923" checksum="79AA687849E48ABD" modified="2017-02-15" version="1">MCDGKISKSSLLLLINEIIKTNIELLKNNEIELSSLSSNDVEDINEKRLTYEEEEQEQEEQEQQQDQEKEKEKKKKYIYNNMYEGNDKINNVKYLENDEKNYINILSSKLKDMGKNIGMKLVERMLIHKNEFNDIKDILKFIGKDIWYILFNKNADKLQTYKKGVYVVTDNDISIYLKYLLIDNGTNKKNNFIHYFLMIIIGIIKGILKRFKIKGYVTYDLNYPHCSFQINIIDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNH1</accession>
    <name>A0A1J1GNH1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00170900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526823.1">
        <property type="nucleotide sequence ID" value="XM_028670030.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730236"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00170900"/>
    <dbReference type="OMA" id="YNCYFLL"/>
    <dbReference type="OrthoDB" id="372593at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="459"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="518"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="2103"/>
            <end position="2122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="2153"/>
            <end position="2171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1523"/>
            <end position="1545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2003"/>
            <end position="2026"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="372"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1525"/>
            <end position="1534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1535"/>
            <end position="1545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2565" mass="309708" checksum="47290FFDEF6F9B02" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNI8</accession>
    <name>A0A1J1GNI8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00174800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526862.1">
        <property type="nucleotide sequence ID" value="XM_028670073.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNI8"/>
    <dbReference type="GeneID" id="39730275"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00174800"/>
    <dbReference type="OMA" id="YHIHCFN"/>
    <dbReference type="OrthoDB" id="379665at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030915">
        <property type="term" value="C:Smc5-Smc6 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011513">
        <property type="entry name" value="Nse1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20973">
        <property type="entry name" value="NON-SMC ELEMENT 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20973:SF0">
        <property type="entry name" value="NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="228" mass="26398" checksum="F234BE574630B07D" modified="2017-02-15" version="1">MEVEWASKILAQLLIKEKCLKEKCVINLMKKFGDVNQIIQHMNEKLEVLGFIVNNELINGEEYLILNCEKLKNPGDNSSEKNSINVKDEYLFNSKFKKIEISLYYLIIDYIINNNKNLKIDNGEITYESLCLKLNIKNANIQKSILDKLIFHNWLKNIDEGKLALGIRFYTDLVKFFPLNNLEKCSLCNNAIIVENSKCINCFSVYHLHCFNALASNLSLCFICKNTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNJ4</accession>
    <name>A0A1J1GNJ4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00175600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526870.1">
        <property type="nucleotide sequence ID" value="XM_028670082.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNJ4"/>
    <dbReference type="GeneID" id="39730283"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00175600"/>
    <dbReference type="OMA" id="QFYKLYK"/>
    <dbReference type="OrthoDB" id="382690at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="46"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="117"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="220"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="389" mass="47564" checksum="C79A2B4F040F99D6" modified="2017-02-15" version="1">MNDEEKVFYKFMENKILLKKFCEEYIKIKKNEEYINKEANEIKLKNCQLENEIEKYKDILKNIEKKKVEEIENNNFEFDIKIKKLEKHMNFLNSCLNTEKENYHLNAKELISLKYENNKLKSDLNKSEYNTEDKENQINQNNITVLNKIYSDIDKKIEDMTNLLNEIKNCRNDAEQKIKDYETLLSNYLKKISDINLKYEQFYKLYKEAEHKNNMSKYKKKVLKNRISELKNCNKLLSNQISTLKKDIKIIEMEKNEYYSLLKKAEKKNLLLYHKLKKNDDKFYSSSDYIDKNDFLWDMLNENIEEVFYNNLKNKSSLIKGDLILSQNVYDYINLKEIEKRPIYLRSKTKRRDPYRLEEFNIKRERKRKNILFYSDNDYDKKKRRKDIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNT1</accession>
    <name>A0A1J1GNT1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Calcium load-activated calcium channel</fullName>
            <shortName evidence="14">CLAC channel</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PGAL8A_00168700</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Calcium-selective channel required to prevent calcium stores from overfilling.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the TMCO1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526801.1">
        <property type="nucleotide sequence ID" value="XM_028670006.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNT1"/>
    <dbReference type="GeneID" id="39730214"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00168700"/>
    <dbReference type="OMA" id="GMFGDFK"/>
    <dbReference type="OrthoDB" id="342726at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005262">
        <property type="term" value="F:calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032469">
        <property type="term" value="P:endoplasmic reticulum calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002809">
        <property type="entry name" value="EMC3/TMCO1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008559">
        <property type="entry name" value="TMCO1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20917:SF0">
        <property type="entry name" value="CALCIUM LOAD-ACTIVATED CALCIUM CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20917">
        <property type="entry name" value="PNAS-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01956">
        <property type="entry name" value="EMC3_TMCO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF023322">
        <property type="entry name" value="DUF841_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01415">
        <property type="entry name" value="DUF106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0106">Calcium</keyword>
    <keyword evidence="5 14" id="KW-0107">Calcium channel</keyword>
    <keyword evidence="4" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="13" id="KW-0407">Ion channel</keyword>
    <keyword evidence="11 14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="12 14 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 14" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="95"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR023322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="CRG93980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="188" mass="21774" checksum="3A579390B110B23F" modified="2017-02-15" version="1">MDETIRKIDIFIIIGIAIGCGIFSEFLSWLFVYRKDTFKSLNEEIKVLYEKVQKEKEDGLISKLDQKKGKKKISTEEIYMQKTKMMTSLKTKSNVITGLIFMSMMPILFSLFEGLTIAILPFKPIFPFTLITHAGVQEKNLYHCSSTFIYTLTLMLTRQNIQKFFGYAPPSGMFGDFKMPDEQADIWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP01</accession>
    <name>A0A1J1GP01_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Tubulin binding cofactor c, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00391900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TBCC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527036.1">
        <property type="nucleotide sequence ID" value="XM_028670267.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP01"/>
    <dbReference type="GeneID" id="39732449"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00391900"/>
    <dbReference type="OrthoDB" id="194775at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007023">
        <property type="term" value="P:post-chaperonin tubulin folding pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007021">
        <property type="term" value="P:tubulin complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017901">
        <property type="entry name" value="C-CAP_CF_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016098">
        <property type="entry name" value="CAP/MinC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006599">
        <property type="entry name" value="CARP_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001079">
        <property type="entry name" value="Galectin_CRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027684">
        <property type="entry name" value="TBCC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012945">
        <property type="entry name" value="Tubulin-bd_cofactor_C_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15139">
        <property type="entry name" value="TUBULIN FOLDING COFACTOR C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15139:SF0">
        <property type="entry name" value="TUBULIN-SPECIFIC CHAPERONE C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07986">
        <property type="entry name" value="TBCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00673">
        <property type="entry name" value="CARP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51329">
        <property type="entry name" value="C_CAP_COFACTOR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51304">
        <property type="entry name" value="GALECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C-CAP/cofactor C-like" evidence="5">
        <location>
            <begin position="125"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="Galectin" evidence="4">
        <location>
            <begin position="205"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="21"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG94215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="333" mass="39440" checksum="08F52CB4B3406A3B" modified="2017-02-15" version="1">MDEELTNNEHIDHDEIILKNIKDIETKIQKLKKNIESNDNKLIEINELNDRTIKLKERLTNIYFQFLKHSSVIIYEKKLKELIKEIESLKYILIQNRNKIEYNDMNINYDDSFFLPENDSIDEEYESKELVDYQIDINQYKLSFQNISNKRIIKGFGETEYSSLLLDNLENCEIIVLDILSSVLIQKIQKCTIWVAAVESSVLIYNCVNCTILTNTKQIRIHDTNDTNFYINTMSSPIIENSKNLSFLQYNFNYDSLSELLKKINIDKNSSKWREVLDFNWQNTEEKSPHFSIIDETQEFHINIKKNLGENKGNITNNSYIIENFPSFLKRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP41</accession>
    <name>A0A1J1GP41_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00177400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000021">
        <property type="protein sequence ID" value="CRG94062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526883.1">
        <property type="nucleotide sequence ID" value="XM_028670097.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP41"/>
    <dbReference type="GeneID" id="39730301"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00177400"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="98" mass="11437" checksum="ACEB6C90F70BCC15" modified="2017-02-15" version="1">MEPEENYDPHSFEDDDSIQNSYVAIRSSDQDNYESLHSNLRIPNQNELNIEEQNVISINSQENEEVYIRNNIPRSFIESFLNNIAFLSTLLFLIVIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPB8</accession>
    <name>A0A1J1GPB8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Small subunit rRNA synthesis-associated protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00385400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526971.1">
        <property type="nucleotide sequence ID" value="XM_028670194.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPB8"/>
    <dbReference type="GeneID" id="39732384"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00385400"/>
    <dbReference type="OrthoDB" id="5600060at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032039">
        <property type="term" value="C:integrator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034472">
        <property type="term" value="P:snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027074">
        <property type="entry name" value="Integrator_9su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46094">
        <property type="entry name" value="INTEGRATOR COMPLEX SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46094:SF1">
        <property type="entry name" value="INTEGRATOR COMPLEX SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16661">
        <property type="entry name" value="Lactamase_B_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="3">
        <location>
            <begin position="71"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="763" mass="90007" checksum="29CE7102B59AF191" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPC3</accession>
    <name>A0A1J1GPC3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">P-type ATPase, putative</fullName>
            <ecNumber evidence="12">3.6.3.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ATPase7</name>
        <name evidence="12" type="ORF">PGAL8A_00397300</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.1" evidence="12"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527090.1">
        <property type="nucleotide sequence ID" value="XM_028670327.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732503"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00397300"/>
    <dbReference type="OMA" id="TWFVISH"/>
    <dbReference type="OrthoDB" id="377733at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140326">
        <property type="term" value="F:ATPase-coupled intramembrane lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000073">
        <property type="entry name" value="P-type ATPase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000080">
        <property type="entry name" value="Putative P-type ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032631">
        <property type="entry name" value="P-type_ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF150">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16209">
        <property type="entry name" value="PhoLip_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="111"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="420"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="469"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1294"/>
            <end position="1319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1331"/>
            <end position="1348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1436"/>
            <end position="1458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1478"/>
            <end position="1497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1504"/>
            <end position="1524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1552"/>
            <end position="1573"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase N-terminal" evidence="10">
        <location>
            <begin position="59"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase C-terminal" evidence="11">
        <location>
            <begin position="1264"/>
            <end position="1368"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase C-terminal" evidence="11">
        <location>
            <begin position="1423"/>
            <end position="1579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="274"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="277"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG94269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1661" mass="192496" checksum="7EF1AC1CA8482527" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPG9</accession>
    <name>A0A1J1GPG9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GDP-L-fucose synthase</fullName>
            <ecNumber evidence="3">1.1.1.271</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">FS</name>
        <name evidence="8" type="ORF">PGAL8A_00390200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; GDP-L-fucose biosynthesis via de novo pathway; GDP-L-fucose from GDP-alpha-D-mannose: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.271" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527019.1">
        <property type="nucleotide sequence ID" value="XM_028670248.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPG9"/>
    <dbReference type="GeneID" id="39732432"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00390200"/>
    <dbReference type="OMA" id="FMYAGDL"/>
    <dbReference type="OrthoDB" id="202470at2759"/>
    <dbReference type="UniPathway" id="UPA00128">
        <property type="reaction ID" value="UER00191"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050577">
        <property type="term" value="F:GDP-L-fucose synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042351">
        <property type="term" value="P:'de novo' GDP-L-fucose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00956">
        <property type="entry name" value="GDP_fucose_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028614">
        <property type="entry name" value="GDP_fucose/colitose_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43238">
        <property type="entry name" value="GDP-L-FUCOSE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43238:SF1">
        <property type="entry name" value="GDP-L-FUCOSE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="7">
        <location>
            <begin position="6"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="343" mass="39965" checksum="6BCD7747910C4BA6" modified="2017-02-15" version="1">MSRICLVTGGTGLLGYSLREIIKNENHDFNENGNEIIINSNDENVIKKYIFLSSKMCDLRNYEETKKFFEKNKFTDIIHFAAHVGGLYANKSNNLNFLTNNLDINSNVVKLCHEYSITRGIFTLSTCIFPEKCELPLIEEKIHDGRCHLSNEGYSLSKRVLEVMVRFYREKYNYEWICIIPTNIYGKYDNFNVRDGHVIPSIIHKMYLAKVNNTNVKLPGDGTAIRQFIYNKDISKILYYILNTYYSKNLTIIKDNIFNVILSTNIPSNELTIKEIANKIKCYLNFNNDVLFDTTEDNGIHKKTSCNDKLMKILENSFEFTCLDKGLKETIDWFISNYENIRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPK3</accession>
    <name>A0A1J1GPK3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Mitochondrial import inner membrane translocase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00182300</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TIM14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527252.1">
        <property type="nucleotide sequence ID" value="XM_028670506.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPK3"/>
    <dbReference type="GeneID" id="39730350"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00182300"/>
    <dbReference type="OMA" id="MWPVVIL"/>
    <dbReference type="OrthoDB" id="240298at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001405">
        <property type="term" value="C:PAM complex, Tim23 associated import motor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001671">
        <property type="term" value="F:ATPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000001">
        <property type="entry name" value="Import inner membrane translocase subunit tim14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12763">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12763:SF28">
        <property type="entry name" value="GEO10507P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012475670" evidence="8">
        <location>
            <begin position="17"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="9">
        <location>
            <begin position="64"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG94431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="114" mass="13081" checksum="5B4423779401B975" modified="2017-02-15" version="1">MWPVVMLLFGGGILFAKKGIKYVKNQKIILHNKKFFFPSSFNANLNIFLKNDLKGFERNMSKSEAYKILNINPTTNKEKIREVHKQLMLKNHPDNGGSTYIAAKVNEAKDVLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPU1</accession>
    <name>A0A1J1GPU1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00182900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527258.1">
        <property type="nucleotide sequence ID" value="XM_028670513.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730356"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00182900"/>
    <dbReference type="OMA" id="TTYYKYI"/>
    <dbReference type="OrthoDB" id="378597at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14754">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14754:SF35">
        <property type="entry name" value="TYPE VII SECRETION SYSTEM ACCESSORY FACTOR ESAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="691"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="962"/>
            <end position="1100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1276"/>
            <end position="1333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1882"/>
            <end position="1916"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="589"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1354"/>
            <end position="1436"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1478"/>
            <end position="1550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="716"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="965"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1000"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1011"/>
            <end position="1100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1276"/>
            <end position="1289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1316"/>
            <end position="1333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1887"/>
            <end position="1913"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2123" mass="254461" checksum="33CDFF969BBC03C1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ64</accession>
    <name>A0A1J1GQ64_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00088200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526000.1">
        <property type="nucleotide sequence ID" value="XM_028671355.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ64"/>
    <dbReference type="GeneID" id="39729406"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00088200"/>
    <dbReference type="OrthoDB" id="386034at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022086">
        <property type="entry name" value="IMCp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12314">
        <property type="entry name" value="IMCp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="344" mass="40724" checksum="EDA3B8ED445B9827" modified="2017-02-15" version="1">MRTVLYNGPFIPEIDAGYNIQANGVIINFLKDPFCFRYNIINESDKNTELNKPLNFIDENIKILNPLTATKLVEVPRYLYKEHIINKNEIIHKNVYVPYVGPVYKIKEVKVPIYKEKIKYIPKIIEKEKIYEIPKIEIKNKIQEKLVYLHKNNIKYKKLNHVVERVIPMLKTDVIEKTVILSNIQNQKILDKDETNKNQAFSDPGTSKELYKLHHQEKNYKRKKIEHIVKEDILQNNEVEEINEKCEIKYDGEIEEINENEILKVEKSKENKEIRKIEENESNIPNCLFPPNLSLSHEIKKKKQLDINILPQKKYLNYSELNLSNISSENTEKSFNLYLSENTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQB6</accession>
    <name>A0A1J1GQB6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00189000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000026">
        <property type="protein sequence ID" value="CRG94495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527313.1">
        <property type="nucleotide sequence ID" value="XM_028670574.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQB6"/>
    <dbReference type="GeneID" id="39730417"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00189000"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="141" mass="17008" checksum="9417E7BB296DFC17" modified="2017-02-15" version="1">MKTFTLCLKIFTFLLLIWIFPFFYKYDSSKSLINKVTLETKIGVKHERTLAEVEISEKKSSYIKKRVKHHPSDEKEIRREYLVYLMDIYITYYSANIITNIVEVLLKEENEMIYKYRDKILNAYRNNISTEMQIPHLSLTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQD9</accession>
    <name>A0A1J1GQD9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00096400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526080.1">
        <property type="nucleotide sequence ID" value="XM_028672244.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQD9"/>
    <dbReference type="GeneID" id="39729488"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00096400"/>
    <dbReference type="OrthoDB" id="390758at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="129" mass="15381" checksum="64CE9A9409086629" modified="2017-02-15" version="1">MDDLQKSRIIDLFNLKKEKDFIDKKDLIIILKSLGFKIYNEIFEDKNYYNFDELNDYVVKFQSNYYAKKKIEKCINFLNPHNNVIKKSVLKTILCENGNKFSEIEFKQFLIDVPVDKDGNINHSDLVEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQG5</accession>
    <name>A0A1J1GQG5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">AP-1 complex subunit gamma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00214800</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527566.1">
        <property type="nucleotide sequence ID" value="XM_028670855.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQG5"/>
    <dbReference type="GeneID" id="39730675"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00214800"/>
    <dbReference type="OMA" id="ACEYLHI"/>
    <dbReference type="OrthoDB" id="28053at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030121">
        <property type="term" value="C:AP-1 adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050840">
        <property type="entry name" value="Adaptor_Complx_Large_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017107">
        <property type="entry name" value="AP1_complex_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008152">
        <property type="entry name" value="Clathrin_a/b/g-adaptin_app_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013041">
        <property type="entry name" value="Clathrin_app_Ig-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008153">
        <property type="entry name" value="GAE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22780">
        <property type="entry name" value="ADAPTIN, ALPHA/GAMMA/EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02883">
        <property type="entry name" value="Alpha_adaptinC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037094">
        <property type="entry name" value="AP1_complex_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00809">
        <property type="entry name" value="Alpha_adaptinC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49348">
        <property type="entry name" value="Clathrin adaptor appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50180">
        <property type="entry name" value="GAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6 9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="GAE" evidence="10">
        <location>
            <begin position="902"/>
            <end position="1011"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR037094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG94751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1014" mass="116813" checksum="CA9D367CD7944D18" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQP0</accession>
    <name>A0A1J1GQP0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA-directed RNA polymerase III subunit RPC4, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00222800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527646.1">
        <property type="nucleotide sequence ID" value="XM_028670944.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQP0"/>
    <dbReference type="GeneID" id="39730755"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00222800"/>
    <dbReference type="OMA" id="SECTFSQ"/>
    <dbReference type="OrthoDB" id="5836119at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007811">
        <property type="entry name" value="RPC4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13408">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13408:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05132">
        <property type="entry name" value="RNA_pol_Rpc4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="207"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="207"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG94831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="336" mass="39473" checksum="FD9CBD685CCD07C0" modified="2017-02-15" version="1">MSNRYNHDEYSLRRSISNTLRKSSLLKNGINNNQNVPLKKFVPNIDNLKNENKPKNEETDKLASLDNKNIQELIKKTISIDLQKETKNENFKNKTNKVFSSQSLDVSLNNQINLLNLENKKENNENTEKKKKTSIDIYELNNISKNIFYNKKCASPNAHFLPLTLPFFNNNEKQKKIRKMLLNKESFFFYIQLPNMLPALIQKEESEEEKKEEKKEEKKEDINESKHKNEKKKEEINDSKQKNEKKKFNISKKDSYELSNISTLPNGKFAKLIIYKNKKIKMKINDILFDVNEGSACTFSQEIGCYIKENSEFIFLGNCDHKIVVTPNIERIIHKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQQ7</accession>
    <name>A0A1J1GQQ7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Rad21/Rec8-like protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00199300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527411.1">
        <property type="nucleotide sequence ID" value="XM_028670683.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQQ7"/>
    <dbReference type="GeneID" id="39730520"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00199300"/>
    <dbReference type="OMA" id="IDKNYMI"/>
    <dbReference type="OrthoDB" id="370957at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008278">
        <property type="term" value="C:cohesin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990414">
        <property type="term" value="P:replication-born double-strand break repair via sister chromatid exchange"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007062">
        <property type="term" value="P:sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039781">
        <property type="entry name" value="Rad21/Rec8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006910">
        <property type="entry name" value="Rad21_Rec8_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12585:SF69">
        <property type="entry name" value="FI11703P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12585">
        <property type="entry name" value="SCC1 / RAD21 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04825">
        <property type="entry name" value="Rad21_Rec8_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rad21/Rec8-like protein N-terminal" evidence="4">
        <location>
            <begin position="48"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="139"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="530"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="533"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="985" mass="115620" checksum="65069E7F4F80EF9E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQR2</accession>
    <name>A0A1J1GQR2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Trafficking protein particle complex subunit 13 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00132800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526445.1">
        <property type="nucleotide sequence ID" value="XM_028674855.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQR2"/>
    <dbReference type="GeneID" id="39729853"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00132800"/>
    <dbReference type="OrthoDB" id="378045at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055428">
        <property type="entry name" value="TRAPPC13_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23643">
        <property type="entry name" value="TRAPPC13_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Trafficking protein particle complex subunit 13 C-terminal" evidence="1">
        <location>
            <begin position="531"/>
            <end position="612"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="620" mass="73419" checksum="14CD8F5102FDF259" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQS0</accession>
    <name>A0A1J1GQS0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Splicing factor U2AF large subunit, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">U2AF2</name>
        <name evidence="10" type="ORF">PGAL8A_00228200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527700.1">
        <property type="nucleotide sequence ID" value="XM_028671004.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQS0"/>
    <dbReference type="GeneID" id="39730809"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00228200"/>
    <dbReference type="OMA" id="LEITWLC"/>
    <dbReference type="OrthoDB" id="10266058at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12230">
        <property type="entry name" value="RRM1_U2AF65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12232">
        <property type="entry name" value="RRM3_U2AF65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000097">
        <property type="entry name" value="U2 snRNP auxiliary factor large subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000568">
        <property type="entry name" value="U2 snRNP auxiliary factor large subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006529">
        <property type="entry name" value="U2AF_lg"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01642">
        <property type="entry name" value="U2AF_lg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23139">
        <property type="entry name" value="RNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="9">
        <location>
            <begin position="441"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="9">
        <location>
            <begin position="573"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="41"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="101"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="180"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="53"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="132"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="203"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="240"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="277"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="332"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="359"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG94885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="811" mass="94162" checksum="7F30ED7C71BBEEFB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR00</accession>
    <name>A0A1J1GR00_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Nucleoside transporter 3, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">NT3</name>
        <name evidence="8" type="ORF">PGAL8A_00228800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527706.1">
        <property type="nucleotide sequence ID" value="XM_028671011.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR00"/>
    <dbReference type="GeneID" id="39730815"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00228800"/>
    <dbReference type="OMA" id="LFRKQYC"/>
    <dbReference type="OrthoDB" id="9986677at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005337">
        <property type="term" value="F:nucleoside transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002259">
        <property type="entry name" value="Eqnu_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10332">
        <property type="entry name" value="EQUILIBRATIVE NUCLEOSIDE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10332:SF10">
        <property type="entry name" value="EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="222"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="341"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="371"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="415"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="442" mass="50801" checksum="9BA90CE45B9D519E" modified="2017-02-15" version="1">MFEQETFCVKISDTSKFVNTAETHIEETYESENIKKVEEIYKVEIEKNDELDEQKYSFWLSISYALMAIISEAPYFIIISMADFFKSAFNVSDVMINEFAIMESIIVIVVCVLLHLIGSYRLKWNLYQPILTVFVLGILYLVILFKRDHIGHKIIIFSAIPLGFILCIAKMTTIKICVLFKKPYCSAYVCGLSLSGFLVFLLYVLGAYVLFPNDENKFCNMFSLFCGTISLLSIICFLILFKIYNLPFVKRLEEKYGDKGLLINKTILVDSFQSLNMIWKYMIVGFLTNFFTYQIYPSIFPTSVDIQKESKGLLSGVLLFGDSSARLVVHNLSSYFIKISFLSYSCVQIFRFALLPIFALIVIYKHYILNNLIFLIFLAYIFGFTNGLISNAVFLKLPEVCNKKNKREYLQLVPNIVYLSLLLGTTVGCATSKIYMKILPII</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR12</accession>
    <name>A0A1J1GR12_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">proton-translocating NAD(P)(+) transhydrogenase</fullName>
            <ecNumber evidence="2">7.1.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">PGAL8A_00212700</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>NAD(+) + NADPH + H(+)(in) = NADH + NADP(+) + H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:47992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="7.1.1.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.1" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527545.1">
        <property type="nucleotide sequence ID" value="XM_028670831.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR12"/>
    <dbReference type="GeneID" id="39730654"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00212700"/>
    <dbReference type="OMA" id="TTHKYVA"/>
    <dbReference type="OrthoDB" id="37244at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008750">
        <property type="term" value="F:proton-translocating NAD(P)+ transhydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006740">
        <property type="term" value="P:NADPH regeneration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05304">
        <property type="entry name" value="Rubrum_tdh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1220:FF:000002">
        <property type="entry name" value="NAD(P) transhydrogenase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1220">
        <property type="entry name" value="TPP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007886">
        <property type="entry name" value="AlaDH/PNT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007698">
        <property type="entry name" value="AlaDH/PNT_NAD(H)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024605">
        <property type="entry name" value="NADP_transhyd_a_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034300">
        <property type="entry name" value="PNTB-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006942">
        <property type="entry name" value="PRK09424.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10160">
        <property type="entry name" value="NAD(P) TRANSHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10160:SF19">
        <property type="entry name" value="PROTON-TRANSLOCATING NAD(P)(+) TRANSHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01262">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05222">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02233">
        <property type="entry name" value="PNTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12769">
        <property type="entry name" value="PNTB_4TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01002">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01003">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="DHS-like NAD/FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52283">
        <property type="entry name" value="Formate/glycerate dehydrogenase catalytic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012294789" description="proton-translocating NAD(P)(+) transhydrogenase" evidence="14">
        <location>
            <begin position="24"/>
            <end position="1145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="142"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="170"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="207"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="244"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="323"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1034"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1060"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1116"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="domain" description="Alanine dehydrogenase/pyridine nucleotide transhydrogenase N-terminal" evidence="16">
        <location>
            <begin position="616"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="domain" description="Alanine dehydrogenase/pyridine nucleotide transhydrogenase NAD(H)-binding" evidence="15">
        <location>
            <begin position="760"/>
            <end position="930"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM01003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="CRG94730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1145" mass="127748" checksum="54A449F9AD6E532B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR14</accession>
    <name>A0A1J1GR14_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00141700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526533.1">
        <property type="nucleotide sequence ID" value="XM_028674953.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR14"/>
    <dbReference type="GeneID" id="39729941"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00141700"/>
    <dbReference type="OMA" id="QFHVTLW"/>
    <dbReference type="OrthoDB" id="381704at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056355">
        <property type="entry name" value="Microp_apicomplexa_16"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23529">
        <property type="entry name" value="Microp_apicomplexa_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013244168" evidence="2">
        <location>
            <begin position="20"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="77" mass="9048" checksum="7514BD447887E201" modified="2017-02-15" version="1">MKLFFFFFNILVFLYRINAQLSEVYDENQKSTQFHFALWTVLVLISAFILGTYATFQIAYTKDSLLYSKINTSNNGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRK6</accession>
    <name>A0A1J1GRK6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00245700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527871.1">
        <property type="nucleotide sequence ID" value="XM_028671194.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRK6"/>
    <dbReference type="GeneID" id="39730985"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00245700"/>
    <dbReference type="OMA" id="NTEQWVI"/>
    <dbReference type="OrthoDB" id="372002at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="362" mass="43617" checksum="B62D553C2FA09FB4" modified="2017-02-15" version="1">MNLIKKKIINSIFLKKWLHNNLRFINNFKNVENCLNDIKTKGKDINVLSLVISNNNLCYCLFKNKIIKKIGLINIKKDIYSYDENSMNTKKKKNYIENVNKRYNYDKDENPLSFNIREILTILNFIKIYSNKEENDSKEGLQNNEDRNSEIINNGNSYKNISKNEIESNNEHINVNEFDNFKDSSSKKKKEWIIGIEKVNEKYEKNRIKEKILSIIVYFMQSIFKCKIIFFCPKEARKYFSNKCNYNLTNREEAYIYIKNKIKNFPKIDENNNSLNCLFSDCYIISFYTYRYYMHELIKNNRKIFNYLEKEVRKNKSFNHILQTLKKTENEKSKNDLRGLLKDRINRIIENEAYKLVDKYIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRN6</accession>
    <name>A0A1J1GRN6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">LMBR1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00249000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527903.1">
        <property type="nucleotide sequence ID" value="XM_028671230.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRN6"/>
    <dbReference type="GeneID" id="39731018"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00249000"/>
    <dbReference type="OMA" id="FWAQFVF"/>
    <dbReference type="OrthoDB" id="73273at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072665">
        <property type="term" value="P:protein localization to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050854">
        <property type="entry name" value="LMBD1_LysCbl_Transport"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16130:SF2">
        <property type="entry name" value="LYSOSOMAL COBALAMIN TRANSPORT ESCORT PROTEIN LMBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16130">
        <property type="entry name" value="LYSOSOMAL COBALAMIN TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="282"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="311"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="352"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="428"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="481" mass="56733" checksum="6EA3B2100337701C" modified="2017-02-15" version="1">MDIIIWFIFFIFILLIFASCWIFYKYFVKANESTLLIEVTFILSLSTSFILVLFIPIDIYLVSNGNLEISNFEINQKIVSKIYHFMFWILIFQAYVVVPFSYFYLKNKEKGKELEYIYELLDMKHTGESAVLFLMGCVVLIGVSFWVTYTSYGIACLPLSFLQQKDIDYEKKEIENRFINLKERERIIKNKYNSNSEVKGNDKYEILKIEQMKRVLSRYNYKLQEVEKISESWLSYIIGIIFTFRVITGLIFLSFSFIIYISLLASIIDKYFNSICAYKCGFVLEQINSIFNLLDSVLIFFSRFFPLDILVIASLAIYIFCCSLYGIVNVGIRIFFIPIYKLKPKKSSPETMLILCFLIIHIILVLIMTLLTIAPNYITYGIQNIKLSDKLGYIKCSLKNDKNSCKMSVLSVFFNKIFFGIPYFANSYFFSNWIFLIMYTFSFIHHIFFKKKSYLDNIDELDLNKDNFDENMNLLPLEKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRP4</accession>
    <name>A0A1J1GRP4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Micro-fibrillar-associated protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00236100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527777.1">
        <property type="nucleotide sequence ID" value="XM_028671091.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRP4"/>
    <dbReference type="GeneID" id="39730889"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00236100"/>
    <dbReference type="OMA" id="FHNERAG"/>
    <dbReference type="OrthoDB" id="1111734at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033194">
        <property type="entry name" value="MFAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009730">
        <property type="entry name" value="MFAP1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15327">
        <property type="entry name" value="MICROFIBRIL-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06991">
        <property type="entry name" value="MFAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Micro-fibrillar-associated protein 1 C-terminal" evidence="3">
        <location>
            <begin position="204"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="138"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="267"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="220"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="138"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="165"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="197"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="279"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="455" mass="55949" checksum="69365754605EED66" modified="2017-02-15" version="1">MSTVNELLNYFVVNDDNELIKKEKNQREKTIIKRYFPGKKPHYAKNVNDNEDDDEDEVDEHDEVFNEQIKNIEENVNNHEKNNLVIQPYKINNESDNRYIRLKNKNINGDEKERIKRRIREVQIIDYEESSKEKDILKENFEENSKADKNIPIRNNEEKEKEKEENEEEEEEEDEEEDEEEEEEDEDEEDEEDIDDSYLKNEGNDNDIIMKHEFVSKNHRKTLIERKTEEEEEKQRIKDINEEKELIEIEKKESAIKETLNQEMMEEKLRNKENNVFSSEEDFEEDEKDEELNEKEYELWKIRHLKRLKRDEMDRKKYEILKMEVKKRRKMTDKEIIEENKKLPHKEKKKKRKMLFMQKYYHRGGFYQDLFEEGKEEIYLRDYNEPVYEDKIDKEKLPKVLQVRRGNFGKQGQTKYTHLLDNDTSRKDSLWQNNDLNFPFKKKKDLFERPTYRKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRQ2</accession>
    <name>A0A1J1GRQ2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Mitotic-spindle organizing protein 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00250800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MOZART1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527919.1">
        <property type="nucleotide sequence ID" value="XM_028671248.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRQ2"/>
    <dbReference type="GeneID" id="39731036"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00250800"/>
    <dbReference type="OrthoDB" id="48571at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000931">
        <property type="term" value="C:gamma-tubulin ring complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031021">
        <property type="term" value="C:interphase microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005819">
        <property type="term" value="C:spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033566">
        <property type="term" value="P:gamma-tubulin complex localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051415">
        <property type="term" value="P:microtubule nucleation by interphase microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090307">
        <property type="term" value="P:mitotic spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022214">
        <property type="entry name" value="MZT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28520">
        <property type="entry name" value="MITOTIC-SPINDLE ORGANIZING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28520:SF2">
        <property type="entry name" value="MITOTIC-SPINDLE ORGANIZING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12554">
        <property type="entry name" value="MOZART1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="72" mass="8316" checksum="C12CA89C96AB362E" modified="2017-02-15" version="1">MSDKEAKKEAIEIIYEISNILNVNLDKETIVILIQLCEYGVSPKILSHIIIQLKKEKEKFLQNLNNNMSSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRZ8</accession>
    <name>A0A1J1GRZ8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Plasmodium RESA N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00001200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528058.1">
        <property type="nucleotide sequence ID" value="XM_028671402.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRZ8"/>
    <dbReference type="GeneID" id="39728534"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00001200"/>
    <dbReference type="OMA" id="NIITSTW"/>
    <dbReference type="OrthoDB" id="10574283at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="284" mass="34528" checksum="78E4355C5BD166D3" modified="2017-02-15" version="1">MSIPNKQNNLLTKETYIESKMNKNYSYTSSFKNKKEKIKSRNNIILYSYKFLTLLFLCFSYILLQIMMQQKNKITSELNLVKNNYRIMYEGDELPNKKESKGNIVLKFLDDEGKNEDENQDENENENEDEDEDEDDDEEFEPYKKLVDLWRQRSTDFTEMILTMWYQWNCGRKTRDMDEDWKGKKFNEWRDKFSLELISDDKKCLDDVTKMVKDKVPVEAVQLYCNHKKELWETRKDQILKEWKIFIHNSLQDWVEEKHRRNNIVYYDDDDDDDDDNQGAEIYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS88</accession>
    <name>A0A1J1GS88_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Co-chaperone p23, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00013200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528174.1">
        <property type="nucleotide sequence ID" value="XM_028671530.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS88"/>
    <dbReference type="GeneID" id="39728654"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00013200"/>
    <dbReference type="OMA" id="KCWFNVT"/>
    <dbReference type="OrthoDB" id="1564555at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012927144" evidence="2">
        <location>
            <begin position="21"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="CS" evidence="3">
        <location>
            <begin position="103"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="355" mass="42375" checksum="53F86F337DC97471" modified="2017-02-15" version="1">MFFFCFFVIYIFILFNVVFSKLNYQNEQMASAFFESHKNYIVTKEDIIDGIEKCWFNVSEYLINESIKQEKDFSNDIKATINTLKQKLDQLVTVSYSNKKIDTVNASFQWAQSPENIFLNIKFSHRWSSPGALKVKNEEIISNKNHFSFSAFSNDSNSLTKKYIVDLTLLHNIIESETKYNFASVGKVVVTLKKEKKKIWNRLLLSKEKIPNMHVWWDMKEKYHGSIQDFLKEEEKKKKKYLEKKRNEKLENVEKENTTELKVENNKIDENGNNNEEKDTLIENKYENEQRDGKKDDEDGEYKEEYDDDEEENENYEEYEDYEIENDINEMSLNEKDLENTESTKKEDIKKDDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSE4</accession>
    <name>A0A1J1GSE4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00393600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527053.1">
        <property type="nucleotide sequence ID" value="XM_028670285.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732466"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00393600"/>
    <dbReference type="OMA" id="IFRITEY"/>
    <dbReference type="OrthoDB" id="384965at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1638"/>
            <end position="1658"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2596"/>
            <end position="2618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="411"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="148"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="417"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2690" mass="324895" checksum="0EC07F284909E83F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSI0</accession>
    <name>A0A1J1GSI0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase</fullName>
            <ecNumber evidence="4 8">4.6.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">IspF</name>
        <name evidence="11" type="ORF">PGAL8A_00015700</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>4-CDP-2-C-methyl-D-erythritol 2-phosphate = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + CMP</text>
            <dbReference type="Rhea" id="RHEA:23864"/>
            <dbReference type="ChEBI" id="CHEBI:57919"/>
            <dbReference type="ChEBI" id="CHEBI:58483"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="4.6.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 4/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the IspF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.12" evidence="4 8"/>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528199.1">
        <property type="nucleotide sequence ID" value="XM_028671559.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSI0"/>
    <dbReference type="GeneID" id="39728679"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00015700"/>
    <dbReference type="OMA" id="LIHAIMD"/>
    <dbReference type="OrthoDB" id="2015434at2759"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008685">
        <property type="term" value="F:2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00554">
        <property type="entry name" value="MECDP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.50">
        <property type="entry name" value="2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00107">
        <property type="entry name" value="IspF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003526">
        <property type="entry name" value="MECDP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020555">
        <property type="entry name" value="MECDP_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036571">
        <property type="entry name" value="MECDP_synthase_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00151">
        <property type="entry name" value="ispF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43181">
        <property type="entry name" value="2-C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE SYNTHASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43181:SF1">
        <property type="entry name" value="2-C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE SYNTHASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02542">
        <property type="entry name" value="YgbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69765">
        <property type="entry name" value="IpsF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01350">
        <property type="entry name" value="ISPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="7 8 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013153650" description="2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase" evidence="9">
        <location>
            <begin position="23"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase" evidence="10">
        <location>
            <begin position="57"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG95388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="233" mass="26969" checksum="570E7C0C44F465F3" modified="2017-02-15" version="1">MFLKIYTYIILIYFILLKLSEEKNYIKKNIFNYLFLNPTFKKNTYKKKKLEIFYNGIRIGQGYDIHQIKVCDENNEIYKNIYTELKDGQNFKKLTIGGVKIPNICVLAHSDGDIIFHSLVDSILGGLNYFDIGTLFSDKNEKNKDKNSSSFLRYTRLLLHKKNYKIGNIDINVIAEVPKIFLIKNQIIKNISSLLSIDESQISIKGKTHEKLGVIGEKKAIECFSNVLLIPKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSI3</accession>
    <name>A0A1J1GSI3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00171800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526832.1">
        <property type="nucleotide sequence ID" value="XM_028670040.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSI3"/>
    <dbReference type="GeneID" id="39730245"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00171800"/>
    <dbReference type="OMA" id="CNYFFFK"/>
    <dbReference type="OrthoDB" id="386071at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="569" mass="69080" checksum="819DDC4EFD419723" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSN5</accession>
    <name>A0A1J1GSN5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00265500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000034">
        <property type="protein sequence ID" value="CRG95452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528263.1">
        <property type="nucleotide sequence ID" value="XM_028671629.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSN5"/>
    <dbReference type="GeneID" id="39731184"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00265500"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="236" mass="28343" checksum="B18BA9A8115B0A76" modified="2017-02-15" version="1">MSYNIASGIYSKISHPWNAVIKSYDFSTVNKDRKFKRINFTHIIFSRPFIQFFAFLFFFLLHNTYEKNYESSFCSSYNVSYIRKLTENNKEGNKGFATGVNLSPWDKFEIEVNTKWGELDKKQKSNNSNIILSSWLTVIIKSKDDEKIKENIDIWFKKSSSIFEKYKPQIDADNEMFNKWKEDLKERKFKNYNPNCTNEAYEEWEKIKYKKVQSMMEYYHNVKADIEGWLENMFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSS3</accession>
    <name>A0A1J1GSS3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00272900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000043">
        <property type="protein sequence ID" value="CRG95529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528338.1">
        <property type="nucleotide sequence ID" value="XM_028671713.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSS3"/>
    <dbReference type="GeneID" id="39731261"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00272900"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="132" mass="15109" checksum="6E118DF86ACCD8BE" modified="2017-02-15" version="1">MRHLLNIFKETLVNNSSTNSNVSASNNNLDSKIDRIILALILTINLFIIFYIIIFIYRLKQRAIHDNLMLEVGSVDSGYADIEDEDIDEEIDEGARIVDVDDSVERTVNERVTLNVHGQINSEEDEVVVRIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GST3</accession>
    <name>A0A1J1GST3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00010900</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the oligosaccharyltransferase (OST) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Endoplasmic reticulum membrane</location>
            <topology evidence="2 10">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the OST1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528153.1">
        <property type="nucleotide sequence ID" value="XM_028671507.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GST3"/>
    <dbReference type="GeneID" id="39728631"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00010900"/>
    <dbReference type="OMA" id="YAYKIDI"/>
    <dbReference type="OrthoDB" id="310030at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018279">
        <property type="term" value="P:protein N-linked glycosylation via asparagine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007676">
        <property type="entry name" value="Ribophorin_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21049:SF0">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21049">
        <property type="entry name" value="RIBOPHORIN I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04597">
        <property type="entry name" value="Ribophorin_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0732">Signal</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011834996" description="Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1" evidence="10">
        <location>
            <begin position="20"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="495"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="516"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG95342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="656" mass="79552" checksum="081E9DBD3F25AE18" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSX0</accession>
    <name>A0A1J1GSX0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA pseudouridine(55) synthase</fullName>
            <ecNumber evidence="2">5.4.99.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00273900</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pseudouridine synthase Pus10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.25" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528351.1">
        <property type="nucleotide sequence ID" value="XM_028671727.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSX0"/>
    <dbReference type="GeneID" id="39731271"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00273900"/>
    <dbReference type="OrthoDB" id="271937at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160148">
        <property type="term" value="F:tRNA pseudouridine(55) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2510">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039894">
        <property type="entry name" value="Pus10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048741">
        <property type="entry name" value="Pus10-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21568">
        <property type="entry name" value="TRNA PSEUDOURIDINE SYNTHASE PUS10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21568:SF0">
        <property type="entry name" value="TRNA PSEUDOURIDINE SYNTHASE PUS10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21238">
        <property type="entry name" value="Pus10_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="196"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="Pus10-like C-terminal" evidence="6">
        <location>
            <begin position="343"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="Pus10-like C-terminal" evidence="6">
        <location>
            <begin position="606"/>
            <end position="751"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF21238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="757" mass="90751" checksum="B9998BC81436BF47" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSY3</accession>
    <name>A0A1J1GSY3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Early transcribed membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ETRAMP</name>
        <name evidence="2" type="ORF">PGAL8A_00180500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527237.1">
        <property type="nucleotide sequence ID" value="XM_028670490.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSY3"/>
    <dbReference type="GeneID" id="39730332"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00180500"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006389">
        <property type="entry name" value="Early_transc_mb_plasmodium"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01495">
        <property type="entry name" value="ETRAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09716">
        <property type="entry name" value="ETRAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="202" mass="23403" checksum="537EC7EE459DE211" modified="2017-02-15" version="1">MNIIKIFYIFNYLLVVNFLTPHLCNNNFNFLKNLNSNVEVHSKSKEKKRKKLILFSFIATALAVSIASSLGIHFYLWKKRKGKPLSDLQYDISESKREIPPSVWDNKHLGKVAVDVLDEAIERGELDVKKALQEGILDENLACPSLESIKKYIREGAEDRFLKLTKSQMEEIENMAHYCLYNIKFISLPKQIRELSMVPEPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSY7</accession>
    <name>A0A1J1GSY7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="8">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PPP6</name>
        <name evidence="10" type="ORF">PGAL8A_00013700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the PPP phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528179.1">
        <property type="nucleotide sequence ID" value="XM_028671537.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSY7"/>
    <dbReference type="GeneID" id="39728659"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00013700"/>
    <dbReference type="OMA" id="MCLKVKY"/>
    <dbReference type="OrthoDB" id="1930084at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07415">
        <property type="entry name" value="MPP_PP2A_PP4_PP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000040">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047129">
        <property type="entry name" value="PPA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45619">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="9">
        <location>
            <begin position="112"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG95368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="308" mass="35744" checksum="96E4B93C609EFEB9" modified="2017-02-15" version="1">MTKSEEKKWIEQLRMNPPKLLDENDLRLVCQRVKEILVEENNVQAISPPVIICGDIHGQFFDLLELFDVGGDIMNNDYIFLGDYVDRGYNSVETFEYLLLLKLLFPKNITLLRGNHESRQITTVYGFYDECFKKYGNANAWKYCTDIFDYLTLAALVDNQIFCVHGGLSPEIKLIDQLRLINRVQEIPHEGAFGDIMWSDPDEVDDWVANPRGAGWLFGPKVTKKFNYINNLELIARAHQLAMEGYRYMFDDSTIITVWSAPNYCYRCGNVAAIMRIDENMNRQMLIFKDTPDSRNSIKNKATIPYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT28</accession>
    <name>A0A1J1GT28_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Octaprenyl pyrophosphate synthase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">OPP</name>
        <name evidence="7" type="ORF">PGAL8A_00021600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528257.1">
        <property type="nucleotide sequence ID" value="XM_028671623.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT28"/>
    <dbReference type="GeneID" id="39728738"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00021600"/>
    <dbReference type="OMA" id="CRRFAYV"/>
    <dbReference type="OrthoDB" id="6921389at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990234">
        <property type="term" value="C:transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004659">
        <property type="term" value="F:prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001:SF69">
        <property type="entry name" value="ALL TRANS-POLYPRENYL-DIPHOSPHATE SYNTHASE PDSS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12001">
        <property type="entry name" value="GERANYLGERANYL PYROPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="504" mass="58516" checksum="EF813CDF93CC492A" modified="2017-02-15" version="1">MILLSKNNVKGFLNYCNTKCYNSLINKNDNIFKKNVFKNNIYYVKKASSVFKELIKESFNKFKQEYLNNKTPNINKALKFCENSNMIFTESLYKEILMCMNVLHYKDQEVDNELNYLHEYFKSKKSDIDPFTLCENKIKIVDEYIYNIIKTNYSNIDEFTSYIYLCKGKKFRIISGIFLKNILSYVDNMLTKSNLKYQNLLKNKAKSPINKSLISKRRALMNSGNRISKEQIDENQYKIIAAAEIIHMGSLLHDDVIDESSQRRGILSLHKKYGNKVSILSGDFLIARAGSVFADTNIPNICKRFACVIESLIKGEFLQTNLRFDNIEDAFKIYLIKSYHKTASLFSHLFASIAVLSFKNEKIIQLCFNLGLHIGMAFQLYDDYLDYKIDNNSKKPILDDVKNNIKTAPLFFSYNYNPDVILSLINKKSFSDNDINNILTYIKSTNSMKKNELCSLLHIKKAFDILSLLVSNCKTMNINEKKKINEYEEGLINIILNVLSRSIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT71</accession>
    <name>A0A1J1GT71_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00291200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528516.1">
        <property type="nucleotide sequence ID" value="XM_028671911.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731445"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00291200"/>
    <dbReference type="OMA" id="NSMNNMD"/>
    <dbReference type="OrthoDB" id="385503at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1604"/>
            <end position="1622"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1688"/>
            <end position="1705"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1711"/>
            <end position="1728"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1735"/>
            <end position="1755"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1761"/>
            <end position="1784"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="745"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1858" mass="222954" checksum="AAB1776FCE644338" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTD4</accession>
    <name>A0A1J1GTD4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00269200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000039">
        <property type="protein sequence ID" value="CRG95490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528299.1">
        <property type="nucleotide sequence ID" value="XM_028671670.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTD4"/>
    <dbReference type="GeneID" id="39731222"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00269200"/>
    <dbReference type="OMA" id="FLDTLMW"/>
    <dbReference type="OrthoDB" id="385784at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3030.10">
        <property type="entry name" value="Gametocyte protein Pfg27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036469">
        <property type="entry name" value="Pfg27_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="253" mass="29600" checksum="84E824D75E7CAF3C" modified="2017-02-15" version="1">MKNLKIFHFFNFLFFIYLSLIILFNINIFGTIKKDALQKEYQKLCKVVGRNLAEAGSSNKVFSIKYVNPNVNVNRLNDFCDRLFLSYCVTTNWLTEPPNSLAATFINNALKIADVIYANLHSERINPSFKLIRNEVTRVKERNALITIYGREPHVIDYMKKLFEMENFLTKQLLHSMVGKTQSILEAIISNEEEVIDKIKDELLKRRLILPDYHVRRMMYRIVRRAHDIALEEGILSKNIPEPVGCYLEEFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTF1</accession>
    <name>A0A1J1GTF1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribonucleotide reductase small subunit, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">RNR</name>
        <name evidence="2" type="ORF">PGAL8A_00277400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ribonucleoside diphosphate reductase small chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528385.1">
        <property type="nucleotide sequence ID" value="XM_028671765.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTF1"/>
    <dbReference type="GeneID" id="39731307"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00277400"/>
    <dbReference type="OMA" id="SNPFPWM"/>
    <dbReference type="OrthoDB" id="10248373at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009263">
        <property type="term" value="P:deoxyribonucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01049">
        <property type="entry name" value="RNRR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.620.20">
        <property type="entry name" value="Ribonucleotide Reductase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012348">
        <property type="entry name" value="RNR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033909">
        <property type="entry name" value="RNR_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030475">
        <property type="entry name" value="RNR_small_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000358">
        <property type="entry name" value="RNR_small_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23409">
        <property type="entry name" value="RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23409:SF18">
        <property type="entry name" value="RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SUBUNIT M2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00268">
        <property type="entry name" value="Ribonuc_red_sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00368">
        <property type="entry name" value="RIBORED_SMALL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="349" mass="40668" checksum="5BBCA37B81F0CDA4" modified="2017-02-15" version="1">MADVINISKVPIFTKKEREFSDIQKRKESNEKILNKESDRFTLYPILYPDVWEFYKKAEASFWTAEEIDLSSDLKDFEKLNENEKHFIKYVLAFFAASDGIVLENLASKFLREVQITEAKKFYSFQIAVENIHSETYSLLIDNYIRDEKERLNLFHAIENIPAVKNKALWAAKWINDTNSFAERIVANACVEGILFSGSFCAIFWFKKQNKLHGLTFSNELISRDEGLHTDFNCLIYSLLENKLPEEVVQNIVKEAVEVERSFICESLPCDLIGMNSRLMSQYIEFVADRLLECLGCSKVFHSKNPFNWMDLISLQGKTNFFEKRVADYQKSGVMAQRKDQVFCLNTDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTP9</accession>
    <name>A0A1J1GTP9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">HSP40, subfamily A, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00309600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528692.1">
        <property type="nucleotide sequence ID" value="XM_028672106.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTP9"/>
    <dbReference type="GeneID" id="39731629"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00309600"/>
    <dbReference type="OMA" id="NALCTKC"/>
    <dbReference type="OrthoDB" id="550424at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10719">
        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.230.10:FF:000001">
        <property type="entry name" value="DnaJ subfamily A member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000003">
        <property type="entry name" value="DnaJ subfamily A member 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000068">
        <property type="entry name" value="HSP40, subfamily A, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.230.10">
        <property type="entry name" value="Heat shock protein DnaJ, cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044713">
        <property type="entry name" value="DNJA1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43888">
        <property type="entry name" value="DNAJ-LIKE-2, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="DnaJ/Hsp40 cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51188">
        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="7">
        <location>
            <begin position="27"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="CR-type" evidence="8">
        <location>
            <begin position="136"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="5">
        <location>
            <begin position="136"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="395"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG95884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="421" mass="48055" checksum="FD5590141A447039" modified="2017-02-15" version="1">MFFSSGFPFDSMGGQQARRKREVNNSKYYEVLNLKKNCTTEEVKKAYRKLAIIHHPDKGGDPEKFKEISRAYEVLADEEKRKLYDEYGEEGLENGEQPADATDLFDFILNAGKGKKKRGEDIVSEVKVTLEQLYNGATKKLAISKDVICSNCEGHGGPKDAKVDCKQCNGRGTKTYMRYHSSVLHQTEVTCNGCRGKGKIFNEKDKCTNCKGGCVLKTRKIIEVYIPKGAPNKHKIVFNGEADEKPNVITGNLVVVLNEKQHPVFRREGVDLFMNYKISLYQSLTGFVAEVTHLDERKILVNCTNTGFIRHGDIREIKEEGMPTYKDPFKKGNLYITFEVEYPMDLVITNEKKEVLKFLKKQNESEKNYDLENSEFEVVTCQAVDKEYLKQRVSKQQQQEAYDDDDHQPEMEGGRVACAQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTQ6</accession>
    <name>A0A1J1GTQ6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein-L-isoaspartate(D-aspartate) O-methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.77</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00304300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.77" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528639.1">
        <property type="nucleotide sequence ID" value="XM_028672047.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTQ6"/>
    <dbReference type="GeneID" id="39731576"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00304300"/>
    <dbReference type="OMA" id="FWPCNSS"/>
    <dbReference type="OrthoDB" id="73890at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004719">
        <property type="term" value="F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000682">
        <property type="entry name" value="PCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579">
        <property type="entry name" value="PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579:SF0">
        <property type="entry name" value="PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01135">
        <property type="entry name" value="PCMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="224" mass="25450" checksum="0925C2799FE53CB5" modified="2017-02-15" version="1">MYSLTEKNHKSLIDNLKRRGIIEDDEVYDTMLQVDRGKYIKENPYVDTPVYISHGVTISSPHMHALSLKRLMSVLKPGSRAIDVGSGSGYLTVCMAIRTNVLENKNSFVLGIERVKDLVDFSIENIKRDKPELLNIENFKIIHKNIYQVNEEEKKELGLFDAIHVGASASELPDILVDLLAEDGKLIIPIEEGYTQVLYEITKKNGNIIKERLFDVCFVSLKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU38</accession>
    <name>A0A1J1GU38_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tryptophan-rich antigen</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00194850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527368.1">
        <property type="nucleotide sequence ID" value="XM_028670635.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU38"/>
    <dbReference type="GeneID" id="39730475"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00194850"/>
    <dbReference type="OMA" id="MEWKENE"/>
    <dbReference type="OrthoDB" id="10574493at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012158940" description="Tryptophan-rich antigen" evidence="1">
        <location>
            <begin position="33"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="197" mass="24464" checksum="BC1DB5E3934096A4" modified="2017-02-15" version="1">MNCINLTFSRYFHLSFLILLCLPLECILKSRSEMYSKLYQKSGYSRILSEKLNNEGFIKDSELIEAELENWDNIKCRMNQIWEDTKYNMISRWSDKSTHVTHSKWIKNNMDNMLKKMQIEFNNYMESLYIMFLKQIELLKKNKESKERWNIWMRFMEWKENEKEKFGKWLKKRDELWEEWMDMLMESVDYNVHRGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU39</accession>
    <name>A0A1J1GU39_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00321500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000048">
        <property type="protein sequence ID" value="CRG96002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528810.1">
        <property type="nucleotide sequence ID" value="XM_028672238.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU39"/>
    <dbReference type="GeneID" id="39731748"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00321500"/>
    <dbReference type="OrthoDB" id="6362699at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="359"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="379" mass="43674" checksum="C2015E73B9634967" modified="2017-02-15" version="1" fragment="single">MALLYNRGCDDFVGDSVTCHMAICPINRCKFETSYCPVQLNSVKVYRPSDNVSNDILKNTFKYKRYGPYKFSRIIILSNNDQDGIVFLYELNPHMDNFPIKTYLCRLRSINQMLSLCESIDPYYLDKSLSFNSYDIINEKNYPTSLKHIKNPRHQIIKSKYKDLYYKEHSCHLIKSKFVSHLRCVNYLCEKDNEVYNSCTDANYSGKLVFLYYFSYERKIKELIYLPESCFKTDNNFACTPYYCERKAINQFSLCEYKEISAIKNIETNSKSLDVIATNPKSLDVIATNPKSLDVIATNPKSLDVIATNPKSLDVIATNPKSLDVIATNPKSLDVIATNPKSLDVIATKPHNVYHQNNLSSSALFAMTFMPFLILFVFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU45</accession>
    <name>A0A1J1GU45_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00223500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527653.1">
        <property type="nucleotide sequence ID" value="XM_028670951.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU45"/>
    <dbReference type="GeneID" id="39730762"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00223500"/>
    <dbReference type="OMA" id="LFYKEMY"/>
    <dbReference type="OrthoDB" id="392692at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="744" mass="90676" checksum="B177F4C4E46E28D0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU72</accession>
    <name>A0A1J1GU72_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fam-b protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00225900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527677.1">
        <property type="nucleotide sequence ID" value="XM_028670979.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU72"/>
    <dbReference type="GeneID" id="39730786"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00225900"/>
    <dbReference type="OMA" id="PSQRWKV"/>
    <dbReference type="OrthoDB" id="361836at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012814283" description="Fam-b protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="129" mass="15368" checksum="1B3BD39BDE2EE81A" modified="2017-02-15" version="1">MKQIVFFFCFFFFKNIVNPEKINDIPLVNYEMIPLQRWKVSAKELIKLKEKLKIFIASEIQKEGSRILRKYYKEFYVLDEDNNEKVSTETILDKEIKTPPFLENTKLDENESKNKIKKSFGINGPILII</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUK1</accession>
    <name>A0A1J1GUK1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00343500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529022.1">
        <property type="nucleotide sequence ID" value="XM_028672473.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUK1"/>
    <dbReference type="GeneID" id="39731965"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00343500"/>
    <dbReference type="OMA" id="KNYGGQF"/>
    <dbReference type="OrthoDB" id="390709at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="211" mass="23824" checksum="5265D51B8DF2D1FF" modified="2017-02-15" version="1">MSYNKTYGGQFMGLSSTANTNNQQKINEKKAEKKIEKKEQKNAEKVIFALSDLRGINISELQNGEIFFFCTIIFDNNDVKLSMEKSNHNSSLILGEYLHSSYSLTFSEEIVLNIPQDSNFARCYVSCITVTESDGKRNIKLEGIGYTDPFPIKECKVYGYANCKLNTAVGAPETQGILKMCVKCVENTHPSIVKPSKPYNAIEEIKQRYEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUR2</accession>
    <name>A0A1J1GUR2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00325500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000053">
        <property type="protein sequence ID" value="CRG96041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528849.1">
        <property type="nucleotide sequence ID" value="XM_028672281.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUR2"/>
    <dbReference type="GeneID" id="39731787"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00325500"/>
    <dbReference type="OMA" id="WFMESLE"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="152"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="221"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="343" mass="42979" checksum="6632C8B065E74CD7" modified="2017-02-15" version="1">MLNRGKFLEACLEEFKKEDKEKYTKKIENDLILMGEEEENISTIMLEKQKLLWKKWVERNKSMLEKWKREEWFINLKKEWENEQKCYGETINESEIIQINAGENPMLEKQKKIWKQWLKKQRIWFIEHSEDKWFNDLLDEYKKEEEYEKELTKRDVKKIKEIHKNIKELEQEKSEETEKSRKKKKLIQKVLIEIHMTVLEEYKKEEMKREIEGFFNIIRNEMKIQENLHEELNILEKIEEERNWNSLLEKKKEDIEKWKREKWFVELMLEWKHNEQKNIKELNNKMLEKKNEERITNIALERQKIVLKKHWEGIRKKNYWIFFLRNVSFEKDKDKKKKIKKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUR8</accession>
    <name>A0A1J1GUR8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminotransferase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00320000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528795.1">
        <property type="nucleotide sequence ID" value="XM_028672221.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUR8"/>
    <dbReference type="GeneID" id="39731733"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00320000"/>
    <dbReference type="OMA" id="AANEHRI"/>
    <dbReference type="OrthoDB" id="10264306at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237:SF80">
        <property type="entry name" value="MOLYBDENUM COFACTOR SULFURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237">
        <property type="entry name" value="MOLYBDOPTERIN COFACTOR SULFURASE MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="1">
        <location>
            <begin position="6"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="393" mass="44836" checksum="6913CB9875CC3E69" modified="2017-02-15" version="1">MLTDEKLVTSRNAVLKFFNTNSNEYSVIFTSGATGALKMIGEYFSWEKESLYYYLRINHNSVLGIREYIAEIGGYFKALNENEISKILYDRKKSQKKNDVNNPINCLFAFPAKDNFAGVLYPLEWIEDIKKYGLSDKCHWYVLADVAAYVPSHKFDLSKYIYLDFAVVSFYKMFGYPTGIGALIVKNSSSRVFKKIYFGGGSVVTAVCDSRICKRQDKNSFSHYEDGTLPFLGINALLFGFDILSKISYDIITNHIKALSEFTFYELINIRHSNFTKVAKVYHAYDSPLDGIIAFNLFDINNKYIPFSLVESIAAFNNIHLRGGCFCNSGACQDYLNLNNEEIIESYKDKNSCTENGSSDNKPFGAIRISFGYLSTFKDSFVFIQFIKDNFVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUX4</accession>
    <name>A0A1J1GUX4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Chromatin remodeling protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SNF2L</name>
        <name evidence="8" type="ORF">PGAL8A_00331500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528905.1">
        <property type="nucleotide sequence ID" value="XM_028672343.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731845"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00331500"/>
    <dbReference type="OMA" id="IIICPRS"/>
    <dbReference type="OrthoDB" id="5857104at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10810:FF:000041">
        <property type="entry name" value="Chromatin remodeling protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000082">
        <property type="entry name" value="ISWI chromatin remodeling complex ATPase ISW1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10799">
        <property type="entry name" value="SNF2/RAD54 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="662"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="958"/>
            <end position="1109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="260"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="304"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="538"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1191"/>
            <end position="1224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1413"/>
            <end position="1433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="260"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="310"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="396"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="409"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="427"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="538"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="560"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1192"/>
            <end position="1202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1203"/>
            <end position="1213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1421"/>
            <end position="1431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1675" mass="196300" checksum="7A8848C899592B2B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUY1</accession>
    <name>A0A1J1GUY1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Petidase, M16 family, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00348400</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529071.1">
        <property type="nucleotide sequence ID" value="XM_028672527.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732014"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00348400"/>
    <dbReference type="OrthoDB" id="952271at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050626">
        <property type="entry name" value="Peptidase_M16"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43690">
        <property type="entry name" value="NARDILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43690:SF17">
        <property type="entry name" value="PROTEIN YHJJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012588439" evidence="8">
        <location>
            <begin position="29"/>
            <end position="2312"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 N-terminal" evidence="9">
        <location>
            <begin position="1000"/>
            <end position="1115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="97"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="142"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1822"/>
            <end position="1851"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="287"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="725"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="112"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="142"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG96266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2312" mass="270656" checksum="3D9777E3AD89F3D2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVQ0</accession>
    <name>A0A1J1GVQ0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Subunit of proteaseome activator complex, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00420400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PA28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529428.1">
        <property type="nucleotide sequence ID" value="XM_028672924.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVQ0"/>
    <dbReference type="GeneID" id="39732736"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00420400"/>
    <dbReference type="OMA" id="KKPPKCG"/>
    <dbReference type="OrthoDB" id="6591885at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008537">
        <property type="term" value="C:proteasome activator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061133">
        <property type="term" value="F:endopeptidase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000045">
        <property type="term" value="P:regulation of G1/S transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061136">
        <property type="term" value="P:regulation of proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.180:FF:000002">
        <property type="entry name" value="Proteasome activator complex subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.180">
        <property type="entry name" value="Proteasome activator pa28, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003186">
        <property type="entry name" value="PA28_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036997">
        <property type="entry name" value="PA28_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009077">
        <property type="entry name" value="Proteasome_activ_PA28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036252">
        <property type="entry name" value="Proteasome_activ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10660:SF2">
        <property type="entry name" value="LD45860P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10660">
        <property type="entry name" value="PROTEASOME REGULATOR PA28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02252">
        <property type="entry name" value="PA28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47216">
        <property type="entry name" value="Proteasome activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="2" id="KW-0647">Proteasome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome activator PA28 C-terminal" evidence="3">
        <location>
            <begin position="129"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="276" mass="33084" checksum="D026AA69A2325F99" modified="2017-02-15" version="1">MESLLNKIDKIEPSDPKIREEYNKFKYDVTKQAIESLKERIPKRIIYFNNLVNVNSEPGTILDTKDLDSNSYKYKINHIEENVRKKHKVNDLDDREKKKDTLDYNMKNYPNHEEKKITIDEKVLYTHYVPSHKQIYAELEKIKAYASELIEVIGNIKLWIQLNVPRIEDGNNFGVGIQEEAIQELARVEESAFNLYDAIVKYYMERAKLSTKVIKYPNVYDYQEAIRELDEKEWIHIKITIIDMRNNYIMLYDLLYKNWEKVVKPKNEDAHHRMTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVU0</accession>
    <name>A0A1J1GVU0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">LCCL domain-containing protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00416300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529386.1">
        <property type="nucleotide sequence ID" value="XM_028672878.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732694"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00416300"/>
    <dbReference type="OrthoDB" id="414826at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.560">
        <property type="entry name" value="Exo-inulinase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="LCCL-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004043">
        <property type="entry name" value="LCCL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036609">
        <property type="entry name" value="LCCL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029365">
        <property type="entry name" value="TMEM238"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28613:SF8">
        <property type="entry name" value="LCCL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28613">
        <property type="entry name" value="SI:CH211-232M10.4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03815">
        <property type="entry name" value="LCCL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00603">
        <property type="entry name" value="LCCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56988">
        <property type="entry name" value="Anthrax protective antigen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69848">
        <property type="entry name" value="LCCL domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50820">
        <property type="entry name" value="LCCL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012294776" evidence="2">
        <location>
            <begin position="21"/>
            <end position="1351"/>
        </location>
    </feature>
    <feature type="domain" description="LCCL" evidence="3">
        <location>
            <begin position="387"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="LCCL" evidence="3">
        <location>
            <begin position="651"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="176"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1131"/>
            <end position="1161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1351" mass="157282" checksum="0D0C9F2FF8D39BD9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWA7</accession>
    <name>A0A1J1GWA7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00412400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000063">
        <property type="protein sequence ID" value="CRG96542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529347.1">
        <property type="nucleotide sequence ID" value="XM_028672834.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732654"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00412400"/>
    <dbReference type="OMA" id="QKVPITH"/>
    <dbReference type="OrthoDB" id="348930at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="815"/>
            <end position="836"/>
        </location>
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        <location>
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            <end position="610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="671"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="387"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="415"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="437"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="487"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="542"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1460" mass="168389" checksum="FFD389E381486C46" modified="2017-02-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWC9</accession>
    <name>A0A1J1GWC9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">XAP-5 DNA binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00414700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529371.1">
        <property type="nucleotide sequence ID" value="XM_028672860.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWC9"/>
    <dbReference type="GeneID" id="39732677"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00414700"/>
    <dbReference type="OMA" id="WEIYKPM"/>
    <dbReference type="OrthoDB" id="1562195at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048337">
        <property type="entry name" value="FAM50A/XAP5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007005">
        <property type="entry name" value="XAP5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12722:SF0">
        <property type="entry name" value="PROTEIN FAM50A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12722">
        <property type="entry name" value="XAP-5 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04921">
        <property type="entry name" value="XAP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAM50A/XAP5 C-terminal" evidence="2">
        <location>
            <begin position="241"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="387" mass="46004" checksum="DFD244BD491F0F79" modified="2017-02-15" version="1">MNFRKHESTADLIDSIINSENGKVQKYVLERKRKEKEFIEKKENIKKKALMAPKLNQMFVINKNDDDKLISETIGLRTVHEYKKIKDEIYSKKRNKDLNENIEENKHNKNRNFNLSFCTDEENDEDDEEEKEEKEEKDQKRKIQNSYSKDNVSNESSLEKKIENSGNNSEKNVKEDLSDINNNNDITYKKENNFKKKIIKDPTVNTSFLKDKERDEKIELKKKELRELYFKLENEEKEKIIEITYSYYDGCGHRRKISVKQKTTIGQFINKCVENLKNEFIQLRSASCETLIFVKEDIILPNYLTFYELIKNKAQGKTGPLFVFDAVENLSGITDIRREKTDTHAGKLVEKKWYEKNKHIFPASKWELYKPLKTYTTSYNDLFNSFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWG7</accession>
    <name>A0A1J1GWG7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cysteine repeat modular protein 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00424100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529465.1">
        <property type="nucleotide sequence ID" value="XM_028672964.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732773"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00424100"/>
    <dbReference type="OMA" id="LFDCSYI"/>
    <dbReference type="OrthoDB" id="10035969at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.20.10">
        <property type="entry name" value="Plasminogen Kringle 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.50.10">
        <property type="entry name" value="Tumor Necrosis Factor Receptor, subunit A, domain 2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056047">
        <property type="entry name" value="CRMPA-like_DUF7630"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056048">
        <property type="entry name" value="CRMPA/B-like_DUF7631"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000001">
        <property type="entry name" value="Kringle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013806">
        <property type="entry name" value="Kringle-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018056">
        <property type="entry name" value="Kringle_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038178">
        <property type="entry name" value="Kringle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011641">
        <property type="entry name" value="Tyr-kin_ephrin_A/B_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11319">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11319:SF35">
        <property type="entry name" value="OUTER MEMBRANE PROTEIN PMPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24633">
        <property type="entry name" value="DUF7630"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24634">
        <property type="entry name" value="DUF7631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07699">
        <property type="entry name" value="Ephrin_rec_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01411">
        <property type="entry name" value="Ephrin_rec_like"/>
        <property type="match status" value="10"/>
    </dbReference>
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        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57440">
        <property type="entry name" value="Kringle-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00021">
        <property type="entry name" value="KRINGLE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50070">
        <property type="entry name" value="KRINGLE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0420">Kringle</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="2143"/>
            <end position="2165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="2177"/>
            <end position="2195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="2244"/>
            <end position="2270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="2330"/>
            <end position="2350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="2393"/>
            <end position="2418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="2444"/>
            <end position="2467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="2473"/>
            <end position="2492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="2512"/>
            <end position="2530"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="2536"/>
            <end position="2559"/>
        </location>
    </feature>
    <feature type="domain" description="Kringle" evidence="5">
        <location>
            <begin position="281"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="2972"/>
            <end position="3009"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3024" mass="356602" checksum="E4D79646E74E0ABA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWK6</accession>
    <name>A0A1J1GWK6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00443600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529658.1">
        <property type="nucleotide sequence ID" value="XM_028673179.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWK6"/>
    <dbReference type="GeneID" id="39732969"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00443600"/>
    <dbReference type="OMA" id="CYLSNLY"/>
    <dbReference type="OrthoDB" id="371219at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="386" mass="46762" checksum="EA0EF7989D75A720" modified="2017-02-15" version="1">MIKSDDLNGSIDKSGDYNSFYIGNIFSEIQDEIKNSCNNENVEKKNIPEYEKAINKIGKENNIINKINIEEYINFINDKKNEYKKKKKEYVIEYINKRRIKKFHYKDMETLFKKYSQFLDFEEKCLLCNNYLSLSFLYFNKHLNEKQNNKRIVKYKYENILNFCVCLEKIEYSKQYISDKKDYSYIDMTHLFKQNASFSINIKKNIIIKEFIKNVKFTEFYKHNSYNGNYYNTFPIKKNYNIDTKYINICKYIEKPKLTIEDVKSLNSHTENFTPVFKIHNANILLTTVEKKLLIECLKVIKKIYFYNKIDKLTVIIFCYLNNLYNIVMRLNAECILCCYSQKHFEFFLYYFFQKNRLPVKRMKMLAMKIYKNEGGHDSKNEDEDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWL1</accession>
    <name>A0A1J1GWL1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00450900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529732.1">
        <property type="nucleotide sequence ID" value="XM_028673261.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWL1"/>
    <dbReference type="GeneID" id="39733042"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00450900"/>
    <dbReference type="OMA" id="KNTAYWA"/>
    <dbReference type="OrthoDB" id="378817at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012588421" evidence="3">
        <location>
            <begin position="20"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="731"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="332"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="692"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="692"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="709"/>
            <end position="718"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="813" mass="96769" checksum="26C6660E205484DF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX75</accession>
    <name>A0A1J1GX75_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00475000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000093">
        <property type="protein sequence ID" value="CRG97171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529974.1">
        <property type="nucleotide sequence ID" value="XM_028673530.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX75"/>
    <dbReference type="GeneID" id="39733283"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00475000"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="138" mass="16697" checksum="FC352DE875E7A74D" modified="2017-02-15" version="1">MKTFTLYLKIFTFLLLIWIFHCFYNYDSSKSLINKDTLQKKIGLKHERMLAEGDISDKKSAYFKKRVEHYPSDEKEIFLCELVLLMDMYFKCYNANIMSNIVQDVLFKKENEMRYKCRDKILNAYRNNISIEKELETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXE8</accession>
    <name>A0A1J1GXE8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Leucine-rich repeat protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">LRR12</name>
        <name evidence="1" type="ORF">PGAL8A_00470500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529927.1">
        <property type="nucleotide sequence ID" value="XM_028673479.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXE8"/>
    <dbReference type="GeneID" id="39733238"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00470500"/>
    <dbReference type="OMA" id="NIFSANC"/>
    <dbReference type="OrthoDB" id="429162at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052394">
        <property type="entry name" value="LRR-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24114:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24114">
        <property type="entry name" value="LEUCINE RICH REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="656" mass="76149" checksum="7B0D555943C482E3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXJ1</accession>
    <name>A0A1J1GXJ1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00321900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000049">
        <property type="protein sequence ID" value="CRG96005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528813.1">
        <property type="nucleotide sequence ID" value="XM_028672241.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXJ1"/>
    <dbReference type="GeneID" id="39731751"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00321900"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="96" mass="11132" checksum="9CF32CAA3E09684F" modified="2017-02-15" version="1">MSYNESNTTATPAVSLNSTLENNTSNSTDNAYNPTYTNRILFIIFFIIYLIVKFYTGRFSQYARHRQNGNNHFDLISIDSGYFENIPEDEQEENVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXP5</accession>
    <name>A0A1J1GXP5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00458800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529811.1">
        <property type="nucleotide sequence ID" value="XM_028673350.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733121"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00458800"/>
    <dbReference type="OMA" id="IKFDYAH"/>
    <dbReference type="OrthoDB" id="371518at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1706"/>
            <end position="1728"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="618"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1979" mass="239695" checksum="E2D133A5A469F122" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY55</accession>
    <name>A0A1J1GY55_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00498800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530217.1">
        <property type="nucleotide sequence ID" value="XM_028673801.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY55"/>
    <dbReference type="GeneID" id="39733521"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00498800"/>
    <dbReference type="OMA" id="SGQNKIH"/>
    <dbReference type="OrthoDB" id="1724687at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000554">
        <property type="entry name" value="Ribosomal_eS7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11278">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11278:SF0">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN ES7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01251">
        <property type="entry name" value="Ribosomal_S7e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="194" mass="22616" checksum="72C740A6BFB31E20" modified="2017-02-15" version="1">MEAIEKKILKRNPSDLEKEIAQCLIDIELSSSSDIKSDAKEIRLLSCDLIEVDKLKKKTILIYIPYKIYVTYVRKIQRKLINELEKKTKKYVVLVAKRTILKAKQKTKAFKIIPRSRTLTSVYDSVLEDIVSPSEIIGKRISMRSDGKRIFKIMLDPKERQRDNIEEKLISFAAVYKKITRREAIFSLPPSNEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY74</accession>
    <name>A0A1J1GY74_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00508700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530315.1">
        <property type="nucleotide sequence ID" value="XM_028673909.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY74"/>
    <dbReference type="GeneID" id="39733620"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00508700"/>
    <dbReference type="OrthoDB" id="10357807at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="101" mass="11389" checksum="09EF0F49FEF6E0C1" modified="2017-02-15" version="1">MTRYVINTIFPNVTYHNYRNLEILNMGNFSLTSINATTPAMILNDVSTNVHVVQKERPNAIVANNVVTRIGENSVIVVNKDQDVIMKRYININPSSIILSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYF7</accession>
    <name>A0A1J1GYF7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">TPL/SMU1 LisH-like dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00507400</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the WD repeat SMU1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530302.1">
        <property type="nucleotide sequence ID" value="XM_028673895.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYF7"/>
    <dbReference type="GeneID" id="39733607"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00507400"/>
    <dbReference type="OMA" id="QSGLCVR"/>
    <dbReference type="OrthoDB" id="538223at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000808">
        <property type="entry name" value="Alternative splicing regulator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045184">
        <property type="entry name" value="SMU1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054532">
        <property type="entry name" value="TPL_SMU1_LisH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17814">
        <property type="entry name" value="LisH_TPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00667">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="TPL/SMU1 LisH-like dimerisation" evidence="9">
        <location>
            <begin position="9"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="212"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="262"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="304"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG97501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="520" mass="59936" checksum="4143F398AFF076D0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYI0</accession>
    <name>A0A1J1GYI0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00328900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000057">
        <property type="protein sequence ID" value="CRG96075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528880.1">
        <property type="nucleotide sequence ID" value="XM_028672316.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYI0"/>
    <dbReference type="GeneID" id="39731818"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00328900"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006496">
        <property type="entry name" value="CHP01606_Plasmodium_spp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09688">
        <property type="entry name" value="Wx5_PLAF3D7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="255" mass="30789" checksum="9DEBDBBF49A5ED64" modified="2017-02-15" version="1">MKTLTLYLKITTFLLLIWMYQCFYNCYTYKTLIDKKRLQIKNELIYERVLTEGDIAGKEQTYAEECQEECPIVKKKKEKKKKYRYIPLVRENPYDRWQNVNNPTLFERFKNETIGMDDKWRDQKWNNEWNKISANKVNELSEIFNQSDISKEEKEKLIYTVKDELFGLFANFLKECKKEIRDNKTVSESMKEMIDNKTVSESMKELTDSKTRSESMKEMIDNKTESESKNEQGKNKIKNQKSNILKFLFKKFENH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYQ3</accession>
    <name>A0A1J1GYQ3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MSP3-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00494800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530171.1">
        <property type="nucleotide sequence ID" value="XM_028673749.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYQ3"/>
    <dbReference type="GeneID" id="39733481"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00494800"/>
    <dbReference type="OMA" id="HATKEIV"/>
    <dbReference type="OrthoDB" id="392935at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="408"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="436"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="513"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="549"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="593"/>
            <end position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="641" mass="70750" checksum="F0A7146D7849E2A6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYU4</accession>
    <name>A0A1J1GYU4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rpr2, RNAse P, putative</fullName>
            <ecNumber evidence="2">3.1.26.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00340500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.5" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528992.1">
        <property type="nucleotide sequence ID" value="XM_028672440.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYU4"/>
    <dbReference type="GeneID" id="39731935"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00340500"/>
    <dbReference type="OMA" id="FSEITGH"/>
    <dbReference type="OrthoDB" id="377379at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="338" mass="40278" checksum="AB80AC867D0440F0" modified="2017-02-15" version="1">MNEKNKEKNEVNAYVNKVKFSLITGDKLIDKRIEYLWNLALSTIYVNAKLSMKYITLIKKISNNNLLFDHICCHYCNLIYIPFYNCEIKEIQDKNTILYKCFLCNHKKRVNLQNLIKQKKNNSFKTNKYPNNSTDLNFFLINDIEKFAIKKKNEDENNDNNKNINEVSINKENINIETKNGENVNTEIENVDNRNIEEEDGEDVNIEIENVDNISINNKNEENIKEEKDDNEEYFKNNIYENMNDLFRIDYGKQNDIIQKSYYNFNSYSNKDEIFNNTNSKIKKNDSSSKNNKIKKRKNENKISRNEESNVSYFNTNDNFLNFNKQKKKKKKNILDIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZC8</accession>
    <name>A0A1J1GZC8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00515800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530386.1">
        <property type="nucleotide sequence ID" value="XM_028673989.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZC8"/>
    <dbReference type="GeneID" id="39733691"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00515800"/>
    <dbReference type="OMA" id="FLKYWVR"/>
    <dbReference type="OrthoDB" id="333715at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="74" mass="9088" checksum="EF8910DEF0959973" modified="2017-02-15" version="1">MEKNILKKYRSFFNFVSDIKNNIEKENSLKFSQELYMKNISKSNYNVKKNTNQIYDNKLFLKYWVRKKRPGARN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZG7</accession>
    <name>A0A1J1GZG7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00526300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530488.1">
        <property type="nucleotide sequence ID" value="XM_028674102.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZG7"/>
    <dbReference type="GeneID" id="39733796"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00526300"/>
    <dbReference type="OMA" id="CNKIYCI"/>
    <dbReference type="OrthoDB" id="377672at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053336">
        <property type="entry name" value="Rhoptry_Surface_Assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37320">
        <property type="entry name" value="AG-1 BLOOD STAGE MEMBRANE PROTEIN HOMOLOGUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37320:SF1">
        <property type="entry name" value="RHOPTRY SURFACE PROTEIN CERLI2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="565"/>
            <end position="599"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="999" mass="121820" checksum="C50B65AD5804FC35" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZJ9</accession>
    <name>A0A1J1GZJ9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Thioredoxin peroxidase 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00529600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peroxiredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530520.1">
        <property type="nucleotide sequence ID" value="XM_028674137.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZJ9"/>
    <dbReference type="GeneID" id="39733829"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00529600"/>
    <dbReference type="OMA" id="NNFGVMR"/>
    <dbReference type="OrthoDB" id="185659at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033554">
        <property type="term" value="P:cellular response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03015">
        <property type="entry name" value="PRX_Typ2cys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000002">
        <property type="entry name" value="Alkyl hydroperoxide reductase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050217">
        <property type="entry name" value="Peroxiredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019479">
        <property type="entry name" value="Peroxiredoxin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10681">
        <property type="entry name" value="THIOREDOXIN PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10681:SF164">
        <property type="entry name" value="THIOREDOXIN PEROXIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10417">
        <property type="entry name" value="1-cysPrx_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 9" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="5 6" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="8">
        <location>
            <begin position="19"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity" evidence="7">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG97719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="214" mass="24579" checksum="7C80BD4C6E12A082" modified="2017-02-15" version="1">MYPLKKLYNPFKTSIRKFSLVTKKAYDFSAQGLNKNNEIIDVQLSSFLGQKYCCLLFYPLNFTFVCPTEIIEFNKHIKSFENKNVELLGISVDSVYSHLAWKNMPIEKGGIGNINFTLVSDINKEICKNYDVLFNNSFALRGLFIIDLLGNIRHKTINDLSIGRNVNEVLRIIDSIIHVDKSGDVCPINWKKGDKSFKPNQESLLDYLNNDIKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZN1</accession>
    <name>A0A1J1GZN1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00532100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530544.1">
        <property type="nucleotide sequence ID" value="XM_028674163.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZN1"/>
    <dbReference type="GeneID" id="39733854"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00532100"/>
    <dbReference type="OrthoDB" id="376626at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="214" mass="25806" checksum="CB6CBA466FFB6034" modified="2017-02-15" version="1">MTITLEDLKSDSLHNFQNKRKYNCRMNFKRFTKRRNKSKEDNKDSHINIKTALIKNEVIGDDNDEFIDNNLMRTCNKFKLHKHNSKIEVYKTNEKKLDKYDYERDQTFCSLTDLEDVVNEDKKKSKFFFYKNKSLNDYNSCFEKKNRKLKWFRLRRKKKKESTVDENLKYLNESVCSNYKDANHRNQLNNSSQYTKKCVLNTVNGIKGVSAWIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZT8</accession>
    <name>A0A1J1GZT8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sexual stage-specific protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00056900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530931.1">
        <property type="nucleotide sequence ID" value="XM_028674594.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZT8"/>
    <dbReference type="GeneID" id="39729094"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00056900"/>
    <dbReference type="OrthoDB" id="385615at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09716">
        <property type="entry name" value="ETRAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013017915" evidence="3">
        <location>
            <begin position="26"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG98134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="143" mass="15488" checksum="B0DF377E6E01E921" modified="2017-02-15" version="1">MNFRKLISSLSLVLILYSIVELAFANADEKTKKSPGKGNPVSTTSSNQSDTSLKDAIDRIPAEAQQALEEIKVISNMLDKKTSVNRNLIIGTAVTNIALLLMLSGLMGYNTRKMAVDDGEGKDKAGKKKDVKGECCKETDEAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H055</accession>
    <name>A0A1J1H055_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NLI interacting factor-like phosphatase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">NIF2</name>
        <name evidence="3" type="ORF">PGAL8A_00037400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530736.1">
        <property type="nucleotide sequence ID" value="XM_028674377.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H055"/>
    <dbReference type="GeneID" id="39728898"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00037400"/>
    <dbReference type="OMA" id="YREDCFE"/>
    <dbReference type="OrthoDB" id="277011at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000200">
        <property type="entry name" value="NLI interacting factor-like phosphatase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011948">
        <property type="entry name" value="Dullard_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02251">
        <property type="entry name" value="HIF-SF_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="2">
        <location>
            <begin position="53"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="326" mass="39169" checksum="B66FAF119E050214" modified="2017-02-15" version="1">MKKKKIGICIYQLFSKLKFYKHIWIKIKDVVKCILKPFILKKKFNFRTYRKRRICPSMTLVLDLDETLIYCTKKKIYNYQKEVDVLINGKYLSLYVCKRPYIDLFFSSLYPLYEIIIFTTSIKSYADTVLNIIDIDHYIDKKFYREDCYEMNQNYYIKNLVNIKKEISKIILIDDSNASGLKYPENFFPIKKWQGDLNDTELLDIIPFFLNLRKVKDIRSICSFRLKSQKEVSKLLSTSSVNEINYLPDDNSKPLYRESLAFQAINYLKIFMHRFRYASSKEQWNELGKKINNKLKSYPFSLSKLKGSSDDEQKKKYRKNVQRKFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H056</accession>
    <name>A0A1J1H056_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">AAA family ATPase, CDC48 subfamily, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">Cdc 48</name>
        <name evidence="7" type="ORF">PGAL8A_00051100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530873.1">
        <property type="nucleotide sequence ID" value="XM_028674529.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H056"/>
    <dbReference type="GeneID" id="39729036"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00051100"/>
    <dbReference type="OMA" id="CIKEHVH"/>
    <dbReference type="OrthoDB" id="370103at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034098">
        <property type="term" value="C:VCP-NPL4-UFD1 AAA ATPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097352">
        <property type="term" value="P:autophagosome maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051228">
        <property type="term" value="P:mitotic spindle disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030970">
        <property type="term" value="P:retrograde protein transport, ER to cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19519">
        <property type="entry name" value="RecA-like_CDC48_r1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000018">
        <property type="entry name" value="Cell division control 48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000012">
        <property type="entry name" value="Transitional endoplasmic reticulum ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029067">
        <property type="entry name" value="CDC48_domain_2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003338">
        <property type="entry name" value="CDC4_N-term_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF171">
        <property type="entry name" value="NUCLEAR VALOSIN-CONTAINING PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01073">
        <property type="entry name" value="CDC48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="ADC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54585">
        <property type="entry name" value="Cdc48 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CDC48 N-terminal subdomain" evidence="6">
        <location>
            <begin position="304"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="524"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="882"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="172"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="229"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="172"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="185"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="232"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="242"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG98076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1143" mass="132411" checksum="06144D24A13B086F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H066</accession>
    <name>A0A1J1H066_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">26S proteasome regulatory subunit RPN8, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPN8</name>
        <name evidence="5" type="ORF">PGAL8A_00425600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M67A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529480.1">
        <property type="nucleotide sequence ID" value="XM_028672982.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H066"/>
    <dbReference type="GeneID" id="39732788"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00425600"/>
    <dbReference type="OMA" id="HAMSIKT"/>
    <dbReference type="OrthoDB" id="10256771at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005838">
        <property type="term" value="C:proteasome regulatory particle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08062">
        <property type="entry name" value="MPN_RPN7_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000040">
        <property type="entry name" value="26S proteasome regulatory subunit RPN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024969">
        <property type="entry name" value="EIF3F/CSN6-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033858">
        <property type="entry name" value="MPN_RPN7_8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540:SF7">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10540">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13012">
        <property type="entry name" value="MitMem_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MPN" evidence="4">
        <location>
            <begin position="22"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="299"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="354" mass="41281" checksum="CA959BD679C46DD6" modified="2017-02-15" version="1">MENDIFEKNRNVLERIYLNKHVVVHPIVLLSIVDHYNRIASNTKKRVLGTILGEKIDGVVHITNSYALPFEEDIKDINIFYIDDNYNENLFNMIRKINTREKIVGWYTTGSNIKPNDIFINEIFYKYHHAPIFLLVNVHTDQSIFPVNAYVAIEKAIHDNKFRKTFIHIPVTIGAFEAEEVGVEFLLKELKSVSTSTLATKVGDKLSSLKSLISKLYEISSYLNDILNGNIEMNIKILYNLQNIFSILPDIENAELIEAFMVKNNDLMLNIYIGSITRSVIALHNLINNKIENKINSEKKKLLENEKEKEKEKEKEKEKEKEKEKEKEKEKEKEKEKGKKRYKEKESKEDSSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H070</accession>
    <name>A0A1J1H070_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histone deacetylase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00027700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530642.1">
        <property type="nucleotide sequence ID" value="XM_028674272.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H070"/>
    <dbReference type="GeneID" id="39728800"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00027700"/>
    <dbReference type="OMA" id="DGFCIFN"/>
    <dbReference type="OrthoDB" id="437693at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000118">
        <property type="term" value="C:histone deacetylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004407">
        <property type="term" value="F:histone deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040029">
        <property type="term" value="P:epigenetic regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09993">
        <property type="entry name" value="HDAC_classIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044150">
        <property type="entry name" value="HDAC_classIV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF23">
        <property type="entry name" value="HISTONE DEACETYLASE 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012204619" evidence="2">
        <location>
            <begin position="18"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="Histone deacetylase" evidence="3">
        <location>
            <begin position="155"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="442" mass="51907" checksum="0F4C100C9960B1A2" modified="2017-02-15" version="1">MFYYLLLLWFCLITTYKFKNISNNSNKVLKKKFSVKTLLYINLEKFYRFVIKKKKEKNKLQNSFDFYLDKFLYSSYNDNKTFYDLNKLNINSNVLSLSKDLLYVQNEINKNVSKSFNESKFQRTYKNQKRYSINSQNPPYVFHPIYSNVNIKKKHRFKIKKYENIFTYLNEANIYDSNFVLPSSNISEIIKYMLKAHNPSFINKMLNIIKNKEQVEMYELDLFPDLICRFLVEISGTILSSLLSLKYSISMHIGGGNHHSKRDRGDGFCIFNDVAIAIYFLLSNKIIENAVILDLDVHQGDGTAEIFENSKCVKTISLHCKNNYPLVKKNSTIDIELEPFIKDNEYLDIYQDVLKNIKKKEFSIIFYLAGVDISEDDDLGFLLISDEGIYKRDYLTYQMAIKNNIPIVTVLSGGYNECEETLTKKHILTFKAAKDSWNSMKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H086</accession>
    <name>A0A1J1H086_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">CGI-201 protein, short form, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00054300</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in pre-mRNA splicing and cell cycle progression. Required for the spliceosome assembly and initiation of the DNA replication.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the crooked-neck family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530905.1">
        <property type="nucleotide sequence ID" value="XM_028674565.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H086"/>
    <dbReference type="GeneID" id="39729068"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00054300"/>
    <dbReference type="OMA" id="HIKVWIS"/>
    <dbReference type="OrthoDB" id="541719at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071007">
        <property type="term" value="C:U2-type catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055433">
        <property type="entry name" value="HAT_Syf1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055430">
        <property type="entry name" value="HAT_Syf1_CNRKL1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045075">
        <property type="entry name" value="Syf1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246:SF3">
        <property type="entry name" value="CROOKED NECK-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23231">
        <property type="entry name" value="HAT_Syf1_CNRKL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23233">
        <property type="entry name" value="HAT_Syf1_CNRKL1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Pre-mRNA-splicing factor Syf1/CRNKL1-like C-terminal HAT-repeats" evidence="10">
        <location>
            <begin position="72"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="Pre-mRNA-splicing factor Syf1-like N-terminal HAT-repeats" evidence="11">
        <location>
            <begin position="306"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="661"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="661"/>
            <end position="675"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF23231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF23233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG98108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="691" mass="84765" checksum="BCB9CF24E1A74667" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H089</accession>
    <name>A0A1J1H089_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00040700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG97977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530776.1">
        <property type="nucleotide sequence ID" value="XM_028674423.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728931"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00040700"/>
    <dbReference type="OMA" id="TIMLEIF"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="283"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="83"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1071"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1140"/>
            <end position="1211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="12"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="87"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="109"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="141"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1402" mass="167158" checksum="2B35F40C7032190C" modified="2017-02-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0K3</accession>
    <name>A0A1J1H0K3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00439400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529616.1">
        <property type="nucleotide sequence ID" value="XM_028673133.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732927"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00439400"/>
    <dbReference type="OMA" id="CQQNNIS"/>
    <dbReference type="OrthoDB" id="392416at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="131"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="154"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1036"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1125"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1169"/>
            <end position="1190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1197"/>
            <end position="1214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1220"/>
            <end position="1242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="745"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="332"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="745"/>
            <end position="759"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1284" mass="151987" checksum="F58597A0A114A455" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H142</accession>
    <name>A0A1J1H142_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Exosome complex component RRP4, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RRP4</name>
        <name evidence="6" type="ORF">PGAL8A_00061000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRP4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530970.1">
        <property type="nucleotide sequence ID" value="XM_028674637.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H142"/>
    <dbReference type="GeneID" id="39729135"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00061000"/>
    <dbReference type="OMA" id="MENIDIH"/>
    <dbReference type="OrthoDB" id="1650at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071034">
        <property type="term" value="P:CUT catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071051">
        <property type="term" value="P:poly(A)-dependent snoRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22525">
        <property type="entry name" value="KH-I_Rrp4_eukar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05789">
        <property type="entry name" value="S1_Rrp4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026699">
        <property type="entry name" value="Exosome_RNA_bind1/RRP40/RRP4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048565">
        <property type="entry name" value="S1_RRP4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21321:SF4">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21321">
        <property type="entry name" value="PNAS-3 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15985">
        <property type="entry name" value="KH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21266">
        <property type="entry name" value="S1_RRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110324">
        <property type="entry name" value="Ribosomal L27 protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0271">Exosome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="S1 motif" evidence="5">
        <location>
            <begin position="106"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG98173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="332" mass="38227" checksum="6908A9CEAF6A109C" modified="2017-02-15" version="1">MDICITTPYDNEIDEIEEFNNRILAVETIKHNKSNLNKNIDSTCPNIKKLVLPGEVILEKKDKDRFLKGSGLYEENEKFYACILGTINYINKLVYVEPLKGKYTGAVGDLLVGKVKDINNDKWVVEIGSYSRALLSISQTNISLFSQRIRLYNDVINMINIYKPNDIIACEVQRILTDGCIILHTRSSIYGKLSNGILITVPQTLIQNQKKHIFVFPFNVQIILGMNGFIWISSPIKKSKDTNPNSIDEDIEGNKFEEVDDTTRRNISIISNIIKLLAKYHININYDIITKIYMQYTTNKNNNPCYILKPYVSDSFLFNYIDQINKKNEEFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1B2</accession>
    <name>A0A1J1H1B2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00466600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529888.1">
        <property type="nucleotide sequence ID" value="XM_028673436.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1B2"/>
    <dbReference type="GeneID" id="39733199"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00466600"/>
    <dbReference type="OMA" id="FICDNFL"/>
    <dbReference type="OrthoDB" id="10045365at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="468"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="501" mass="59900" checksum="43B9B7262C85FC66" modified="2017-02-15" version="1">MHINFFFLICLFFYILYNYKFLIKGSLRILPSNNLIDGITIHLTYKFIKYKVYARGIYLNVNFESVNSVKSLIEKYKNIRNLYCNLNKNNEEEIIDGDILTTNNCVIFINIKYKDHLKNIYHLMEYLNLNTSATALIFICDNFLYENEIYNPHEDLNLTIIQPSILTYLISYDLISNYEKKNFDEYTFELYWGVNKKTDIVHIVYHLDFGKYFNYSFFIYMKRFFLELKNHLTYEIQFSIHKNFTIEPRFCFIRDSSYCISKPDYINSNVVREVVEQQVRSLCIYELTLIDDDEFQENSIDNKNILLKKNNNYNLSNSNETSYLNYYSITKKEKLKERKKKMFSEIYIHYINALFDFTFEKKYCSSESNDLTKKCSDKILSVLNVSVKDVDNCFLNNFHTYMKNMIKSKFYVYSIEINDKTYKIKLNKDISIKLICSAFKSMPYQCKDYLANQIFEMENEKENSDANLIAFSFLLISISVHIIGSFLNYLIPKLIDVNEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1W2</accession>
    <name>A0A1J1H1W2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00509600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 5"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530324.1">
        <property type="nucleotide sequence ID" value="XM_028673919.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1W2"/>
    <dbReference type="GeneID" id="39733629"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00509600"/>
    <dbReference type="OMA" id="KHTRRQC"/>
    <dbReference type="OrthoDB" id="1902587at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43811">
        <property type="entry name" value="FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43811:SF26">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP16-1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="6">
        <location>
            <begin position="103"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="216" mass="26003" checksum="6672BC2BDF450445" modified="2017-02-15" version="1">MVNFIGYIFFKLYEKKKISLLKFYFRNKKNIFNGFHKFFFISLNSYFIKKLLFSKNINIFHLEEKRSTYLEKKYRSDTPYLKTESGILYKDIIDGEDITVEKGDIVYIHYQGKTTNDFRIIESTFKSIFPVKITAGFYDQKHIRAIYEIVIGMKKNTRRQCIIPPHLAYPYHFPNQPLIYEIDVVKIIKKNSQKETFLQKMKMKIENIKIAISEYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2S8</accession>
    <name>A0A1J1H2S8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein HIRA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">CAF1</name>
        <name evidence="11" type="ORF">PGAL8A_00023000</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the WD repeat HIR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530596.1">
        <property type="nucleotide sequence ID" value="XM_028674222.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2S8"/>
    <dbReference type="GeneID" id="39728753"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00023000"/>
    <dbReference type="OrthoDB" id="538223at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000417">
        <property type="term" value="C:HIR complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055410">
        <property type="entry name" value="Beta-prop_CAF1B_HIR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031120">
        <property type="entry name" value="HIR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13831">
        <property type="entry name" value="MEMBER OF THE HIR1 FAMILY OF WD-REPEAT PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13831:SF0">
        <property type="entry name" value="PROTEIN HIRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24105">
        <property type="entry name" value="Beta-prop_CAF1B_HIR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0678">Repressor</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3 7 8" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="CAF1B/HIR1 beta-propeller" evidence="10">
        <location>
            <begin position="136"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="186"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="289"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="356"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="673"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="359"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="409"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="434"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="673"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="683"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="709"/>
            <end position="811"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF24105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG97795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1033" mass="122920" checksum="0D7337201A3559C8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2Y7</accession>
    <name>A0A1J1H2Y7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00527900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530503.1">
        <property type="nucleotide sequence ID" value="XM_028674118.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2Y7"/>
    <dbReference type="GeneID" id="39733812"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00527900"/>
    <dbReference type="OMA" id="MCEEDEV"/>
    <dbReference type="OrthoDB" id="375337at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="109" mass="12885" checksum="B1173EF072CC82D0" modified="2017-02-15" version="1">MAYEKEKSDKINIKTYKKDEIVIYEEDDVFSNSTLSDVDNSYIFWKNGIEERDIFELCNQFECSEDECEKNDIKENLNASKSYSNIEINTMPVEINNKFESNLLTEIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H455</accession>
    <name>A0A1J1H455_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00056500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530927.1">
        <property type="nucleotide sequence ID" value="XM_028674590.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H455"/>
    <dbReference type="GeneID" id="39729090"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00056500"/>
    <dbReference type="OrthoDB" id="529194at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG98130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="104" mass="12027" checksum="72B457DC0F33038A" modified="2017-02-15" version="1">MNNTCKYLYRNVIKSCNKTFNKDVEAKINVLNGIKNIIRQNLKTAEEKDIKQQLIEANDFIKDHIIQAVYNNSTGNYKVHINEDQVKKGSITLGTKNEKKIPFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2012-05-16" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>H7CDX4</accession>
    <name>H7CDX4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Apicoplast ribosomal protein S17, putative</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="1">Small subunit ribosomal protein 17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rps17</name>
        <name evidence="2" type="synonym">RPS17</name>
        <name evidence="2" type="ORF">PGAL8A_API01800</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <geneLocation type="apicoplast" evidence="1"/>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2012" name="Mol. Biol. Evol." volume="29" first="2095" last="2099">
            <title>The Plasmodium Apicoplast Genome: Conserved Structure and Close Relationship of P. ovale to Rodent Malaria Parasites.</title>
            <authorList>
                <person name="Arisue N."/>
                <person name="Hashimoto T."/>
                <person name="Mitsui H."/>
                <person name="Palacpac N.M.Q."/>
                <person name="Kaneko A."/>
                <person name="Kawai S."/>
                <person name="Hasegawa M."/>
                <person name="Tanabe K."/>
                <person name="Horii T."/>
            </authorList>
            <dbReference type="PubMed" id="22396524"/>
            <dbReference type="DOI" id="10.1093/molbev/mss082"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">A8</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">8A</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AB649424">
        <property type="protein sequence ID" value="BAL70744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LN835293">
        <property type="protein sequence ID" value="CRG98233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009325460.1">
        <property type="nucleotide sequence ID" value="NC_031963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="H7CDX4"/>
    <dbReference type="GeneID" id="30315796"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_API01800"/>
    <dbReference type="OMA" id="KVICISY"/>
    <dbReference type="OrthoDB" id="372397at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Apicoplast API"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0933">Apicoplast</keyword>
    <keyword evidence="1" id="KW-0934">Plastid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAL70744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="74" mass="9140" checksum="C93538A76103502E" modified="2012-05-16" version="1">MNIKIGYVLKILNKNIKLICISFYRYNIKYKKLKLINKFITVYDNRNEIVKNDYILFKYYKKSKYCNFKVVKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL61</accession>
    <name>A0A1J1GL61_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00084600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525964.1">
        <property type="nucleotide sequence ID" value="XM_028670954.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL61"/>
    <dbReference type="GeneID" id="39729370"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00084600"/>
    <dbReference type="OMA" id="YPHISAF"/>
    <dbReference type="OrthoDB" id="10054414at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="220" mass="25412" checksum="EEBD097EF21A223E" modified="2017-02-15" version="1">MPTQNNLNSGKIDAIKNYIQNFDYKNTNESINGFVQLLKEINIKMVVFDFDLTIIGSHSGGYIDKLNDVDNIGLSVTNDFKIFSKALCLNNIKITVATFSDEEAIRYSKRSSPNLIAGEELVHHCLKKSKCDTKIEKVYAYYPYFYKDPEKYRALQLEKPMTNDKSFHLEKIRLEFFVNFDEIIFIDDDINNCVSAKKEGYITFNVTGKDGFNFKNIKIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLM2</accession>
    <name>A0A1J1GLM2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00101600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526132.1">
        <property type="nucleotide sequence ID" value="XM_028672821.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLM2"/>
    <dbReference type="GeneID" id="39729541"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00101600"/>
    <dbReference type="OrthoDB" id="363718at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="333" mass="39810" checksum="A836EF33B509F96B" modified="2017-02-15" version="1">MAISLCKILRRNNKRVHYEKGKYIIPKLDTTLDTKFDESGEENIFDPPLKAKDDLPLYMQPSENNKSWSEEWRDKGLKKEENKKHNFLSSDNYAYNVPYNYKIVIPTKKNVKDDKNIKEEYSRDVSDTLSYTDFCGFRNPSLSTFDNYRYWQDSGFKKFLNRIFPIKIPEHKKVDPLLREYIYFLHSFDPYRFTFKKLSGRYFFPESTIKLIYKEESVKRFLAENQLCDEKTKRITKKEAILKIKELIYSKKIGYKEIGDYENIKNEDDEFVGYKNTFDQINRQVIQVESISSFPLPDRRDPVPKRVDIDMPVFNSANVKIMNWINPNDKVIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLQ9</accession>
    <name>A0A1J1GLQ9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00096500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526081.1">
        <property type="nucleotide sequence ID" value="XM_028672255.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLQ9"/>
    <dbReference type="GeneID" id="39729489"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00096500"/>
    <dbReference type="OrthoDB" id="284292at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.250">
        <property type="entry name" value="Flavinator of succinate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005631">
        <property type="entry name" value="SDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036714">
        <property type="entry name" value="SDH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03937">
        <property type="entry name" value="Sdh5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109910">
        <property type="entry name" value="YgfY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="125" mass="14911" checksum="993F3B2BAF13A82E" modified="2017-02-15" version="1">MNHVTIFLRKLSTKNVNSEDLNILKKKIRYRFKSVGMLELDTIINNYLNVNMNKIDKDKVNLLYNLVDIDTSNLLKLFYFYSNKQNHNVDKLSHYLKNKDKKEITDTFKLLIDILNHNEKFLSSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLZ2</accession>
    <name>A0A1J1GLZ2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00114400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526260.1">
        <property type="nucleotide sequence ID" value="XM_028674243.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLZ2"/>
    <dbReference type="GeneID" id="39729669"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00114400"/>
    <dbReference type="OMA" id="QFGEKQQ"/>
    <dbReference type="OrthoDB" id="311468at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="12"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="200" mass="23444" checksum="A81EBCE72F3ACD35" modified="2017-02-15" version="1">MEKNDRKFIGGKLKLKVKKKKISKKKEILEEKKKNTSNENEHIKKKNINDEMNIINGSGRIVTIKNTIQGFETRFINEVKVGYEIILKHPTSLQEEKRVVTSILSNKTLLINEEFSTDISTTCTYFIKKVESKQEKNEDDNINLQYAKIIEQKPKNDVIKIRKKVGLWSYKIVDKKIKGNLTNEQKLDERVKSGRDKFCW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM31</accession>
    <name>A0A1J1GM31_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Parasite-infected erythrocyte surface protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">PIEPS15</name>
        <name evidence="4" type="ORF">PGAL8A_00099900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526115.1">
        <property type="nucleotide sequence ID" value="XM_028672632.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM31"/>
    <dbReference type="GeneID" id="39729523"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00099900"/>
    <dbReference type="OrthoDB" id="270293at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005793">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005537">
        <property type="term" value="F:D-mannose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051136">
        <property type="entry name" value="Intracellular_Lectin-GPT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12223:SF28">
        <property type="entry name" value="LECTIN, MANNOSE BINDING 1 LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12223">
        <property type="entry name" value="VESICULAR MANNOSE-BINDING LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012317354" evidence="3">
        <location>
            <begin position="22"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="461"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="358"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="491" mass="57441" checksum="5BFCE1A10CC38562" modified="2017-02-15" version="1">MKNYIILYILIVVVSIFLKRCINETRNTNYLPLHSFKSPFTINDLNNGWILDYSTTSTNEYLVLIPNVYNRRGLLYHDKPIISDSLFIEFSFYIRKKYYKESLDDKYYQKNDTKPIDYKTNIEEENKTNGFGLWILENEFSIKNANNENNELDENEFILYGLKKRFNGIGIFFQLKGNELIVSGFVNNGSNDISVNESVVKSHNFNSLHFNGLITVRVSLQNNEISVSFLDSKNSEFQQSISIKNQISKKNYIGFSAFNFKEDENIPLTNVNKYEPTFVGIKELRIFTNYLNEENERNEDELLNDKNKNDISANDLNSSVNDILKELSPHQDQINHTEALKTLTKIFQKFMVYQINYEKKLLQNIDTMKDKIQIMQSELKLIKKSCINKSEDPKHFQKIFTTELSGLKNLFHSHTQHHRKNIEDITNKLTKKIDNNQELKMLAEKAEKLENIINKGNSTTYIFSIGFAGLIITTLILIYKKIRDVEKKHIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GME4</accession>
    <name>A0A1J1GME4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00112700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526243.1">
        <property type="nucleotide sequence ID" value="XM_028674054.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GME4"/>
    <dbReference type="GeneID" id="39729652"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00112700"/>
    <dbReference type="OMA" id="KDDHMNN"/>
    <dbReference type="OrthoDB" id="380113at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="522" mass="63325" checksum="B88E536B42F67E29" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMG7</accession>
    <name>A0A1J1GMG7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL4m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00115100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526267.1">
        <property type="nucleotide sequence ID" value="XM_028674321.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMG7"/>
    <dbReference type="GeneID" id="39729676"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00115100"/>
    <dbReference type="OMA" id="NWTFPAV"/>
    <dbReference type="OrthoDB" id="275876at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1370.10:FF:000013">
        <property type="entry name" value="Putative mitochondrial ribosomal protein L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_uL4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013005">
        <property type="entry name" value="Ribosomal_uL4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_uL4_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746:SF6">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL4M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="Ribosomal protein L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="557"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="569"/>
            <end position="627"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="627" mass="74827" checksum="FCC628BEFCB18FC5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GML3</accession>
    <name>A0A1J1GML3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Elongation factor G, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">EF-G</name>
        <name evidence="9" type="ORF">PGAL8A_00130900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526426.1">
        <property type="nucleotide sequence ID" value="XM_028674835.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GML3"/>
    <dbReference type="GeneID" id="39729834"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00130900"/>
    <dbReference type="OrthoDB" id="198619at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032790">
        <property type="term" value="P:ribosome disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01886">
        <property type="entry name" value="EF-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03713">
        <property type="entry name" value="EFG_mtEFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04088">
        <property type="entry name" value="EFG_mtEFG_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.240:FF:000001">
        <property type="entry name" value="Elongation factor G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000029">
        <property type="entry name" value="Elongation factor G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035649">
        <property type="entry name" value="EFG_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43261:SF1">
        <property type="entry name" value="RIBOSOME-RELEASING FACTOR 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43261">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012113926" evidence="7">
        <location>
            <begin position="31"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="domain" description="Tr-type G" evidence="8">
        <location>
            <begin position="95"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="736"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="741"/>
            <end position="755"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="947" mass="110641" checksum="D17CCC613217EA38" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMQ8</accession>
    <name>A0A1J1GMQ8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00140300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526519.1">
        <property type="nucleotide sequence ID" value="XM_028674938.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729927"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00140300"/>
    <dbReference type="OMA" id="MINHNVN"/>
    <dbReference type="OrthoDB" id="372934at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1762"/>
            <end position="1797"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1567"/>
            <end position="1598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1779"/>
            <end position="1789"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2649" mass="306791" checksum="7C30CC1818E27E0F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMT9</accession>
    <name>A0A1J1GMT9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">MYND finger protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00135600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526473.1">
        <property type="nucleotide sequence ID" value="XM_028674886.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMT9"/>
    <dbReference type="GeneID" id="39729881"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00135600"/>
    <dbReference type="OMA" id="LIHEAYC"/>
    <dbReference type="OrthoDB" id="432970at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052298">
        <property type="entry name" value="ZMYND10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13244">
        <property type="entry name" value="ZINC FINGER MYND DOMAIN CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13244:SF7">
        <property type="entry name" value="ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="451"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="490" mass="59052" checksum="DF15C8E9C33A7891" modified="2017-02-15" version="1">MNISEFEFFNYANNLKYIEILDLFSKEWFENHKNIVFINAYLHSNNDILDNIGDDRIDVIVNKFEILLKEIITIYFIRFINFEEGYKNKKECLSAEENKELKNMECFKKNTDIEACNNFRISSYISLYHEMSILNIFEFLLFSDSIYESIDSHMINLYAYIYSNLVAFLKTSSDEYFVKPMNELSISEMLKEENDKTYNIDKLKIYINVINTLRNITDRIHLLNNTVVNKIVDYDILLILIPLMEKKPWRKENYIFEKNEWIKIEDNTLATVEKQLWLILYTLILNKSCQEKYEMTNYRRNNILKLRKYMNENLYEQIPPLKTLHIFIEHLYISKNIYPEKKNSYLIIDVVPDIFDKIKNDILKNKKEIISLLNNVKIKKDVLENISNVYFSIYEFDQENNKSINKSSSTFIYFLLILKIHNINILILEYQNASIKRNEKKKTTTEEYYICNNCKENAELQCSQCKRIYYCSKECQMKDWFNHREECSNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN70</accession>
    <name>A0A1J1GN70_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00141500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526531.1">
        <property type="nucleotide sequence ID" value="XM_028674951.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN70"/>
    <dbReference type="GeneID" id="39729939"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00141500"/>
    <dbReference type="OMA" id="MTTISSW"/>
    <dbReference type="OrthoDB" id="369651at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="125" mass="14542" checksum="C52114321A03918F" modified="2017-02-15" version="1">MKYSAFKNSLRFASKFCQKNNYKVYMNSVPQFSTFTYGKHIKTNPLTSRLDDLLKKNSNLISIMSVNGLDDLITQSSKIESVSIAEWLLNLVEEYQLMLSCVNMTTIRSWFSIRSIRLSTKFFKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN76</accession>
    <name>A0A1J1GN76_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00149500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526609.1">
        <property type="nucleotide sequence ID" value="XM_028675038.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN76"/>
    <dbReference type="GeneID" id="39730019"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00149500"/>
    <dbReference type="OMA" id="PHIVVHG"/>
    <dbReference type="OrthoDB" id="64915at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038375">
        <property type="entry name" value="NDUFAF7_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="657"/>
            <end position="690"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1262" mass="147130" checksum="D3E87A21CB390AFA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNM4</accession>
    <name>A0A1J1GNM4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Reticulon domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00170400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG93997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526818.1">
        <property type="nucleotide sequence ID" value="XM_028670025.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNM4"/>
    <dbReference type="GeneID" id="39730231"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00170400"/>
    <dbReference type="OMA" id="NRMENVT"/>
    <dbReference type="OrthoDB" id="384272at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003388">
        <property type="entry name" value="Reticulon"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02453">
        <property type="entry name" value="Reticulon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Reticulon" evidence="7">
        <location>
            <begin position="8"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="180" mass="21572" checksum="7E5308AD5FE3E217" modified="2017-02-15" version="1">MNVNSKNIVTLSIFSSINSLYILLYILNQTFLQIICTLCIMLLLLSGLVVFLKVHKISEYKEDDKLEIISKEKIEYCVIYLYEQLNDKLTIIRQYLLWNNRMKNITVIIIIYLLGNILSFINFNVFFYLLTWVIFLYNYINDTYINNAYKMIHPIYVNIKEQAKYLYDNIPKLQHLKKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNP6</accession>
    <name>A0A1J1GNP6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00380900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526926.1">
        <property type="nucleotide sequence ID" value="XM_028670145.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNP6"/>
    <dbReference type="GeneID" id="39732339"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00380900"/>
    <dbReference type="OMA" id="YELIFSC"/>
    <dbReference type="OrthoDB" id="371576at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="266" mass="31015" checksum="569A1DD9082B7A8A" modified="2017-02-15" version="1">MMGSEVSFKKKIFGNEFSKKKKANKKIILVNMIYLMILFLICFLGGILLGFLTTSYTPAIHIIENDKNVFHFLSKDNKIIIGGKLDIKLNLRNNTILSYIFYSENVKYFYYPIGINYSCLLYNGGLQKSSNQIPLSYKSEIGIPLNNNEDIFATKLSIKIKYTLLELSSVIYTIPLHLGYEITDEYKQEIQPLYNDCKNFNRIYFSIRLDQLHTLNKIRKVYSDKKYELIFYCNCYIDNKVDSFFNSSPVNKKIILNNLINNPNLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNS1</accession>
    <name>A0A1J1GNS1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">BOS complex subunit TMEM147</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Transmembrane protein 147</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00383100</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TMEM147 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526948.1">
        <property type="nucleotide sequence ID" value="XM_028670169.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNS1"/>
    <dbReference type="GeneID" id="39732361"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00383100"/>
    <dbReference type="OMA" id="ECANIID"/>
    <dbReference type="OrthoDB" id="9993532at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019164">
        <property type="entry name" value="TMEM147"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12869:SF0">
        <property type="entry name" value="BOS COMPLEX SUBUNIT TMEM147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12869">
        <property type="entry name" value="SMALL SEVEN TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09767">
        <property type="entry name" value="DUF2053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="35"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="135"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="228"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="254"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00034899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG94127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="263" mass="30901" checksum="101271AD24D770DF" modified="2017-02-15" version="1">MSLFHFVNCSLTTFIPYYIIFDGFKLSKDVGSTKLFVIVCFYYVISQILKLFVLAFFSIGLLQNMNLFNIIFQECANIIDLAGIYYILSHKHTNTINLKERILSVGLSWGFYDSLATNFFPFFIGGRSMDFSMKYIYRSILANTFLFSNLSKTCLLFMWIKNPFHKKKITFIYPLLIYFTFILPLVNKIILINEDSFNIKIFILLFLQLAITIFLSWITKCLFSSQSNNVEQKKKEKDKDDDENQMNKDIIKDGKKKSRKKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNX1</accession>
    <name>A0A1J1GNX1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">NIF4</name>
        <name evidence="10" type="ORF">PGAL8A_00388900</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527006.1">
        <property type="nucleotide sequence ID" value="XM_028670234.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732419"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00388900"/>
    <dbReference type="OMA" id="HYENLKD"/>
    <dbReference type="OrthoDB" id="10249888at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008420">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039189">
        <property type="entry name" value="Fcp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081">
        <property type="entry name" value="RNA POLYMERASE II CTD PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081:SF36">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="9">
        <location>
            <begin position="465"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="71"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="363"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="302"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="813"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="72"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="111"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="364"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG94185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1370" mass="163842" checksum="A5D49164DDFD03D3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP17</accession>
    <name>A0A1J1GP17_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">G-protein coupled receptor, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00072700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525845.1">
        <property type="nucleotide sequence ID" value="XM_028674878.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP17"/>
    <dbReference type="GeneID" id="39729252"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00072700"/>
    <dbReference type="OMA" id="LSLYFEW"/>
    <dbReference type="OrthoDB" id="10257263at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031179">
        <property type="term" value="P:peptide modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04794">
        <property type="entry name" value="euk_LANCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007822">
        <property type="entry name" value="LANC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12736">
        <property type="entry name" value="LANC-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12736:SF7">
        <property type="entry name" value="LANC-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05147">
        <property type="entry name" value="LANC_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01950">
        <property type="entry name" value="LANCSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM01260">
        <property type="entry name" value="LANC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158745">
        <property type="entry name" value="LanC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="209"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="358"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="366"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="367"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR607822-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="450" mass="53243" checksum="5EC2D3295CDD8EF8" modified="2017-02-15" version="1">MADDNRYISNKYLEEFEENELNLNIIKKKIIEFSLKLNNEIENHRNYSVYCGVGGILYMNIILYECSKDVKYLELGKNIIRYLNNHKQKNTITFLEGITGIYSLSSMLYHYLENKKSFSYIELLVNHLRYNKDELRSVNEECELLYGKCGYIYSFLFCRNVWLNSIYKNTILKNLYFIMNSIFEYGLTKCTNMRNITSLSLYFEWHGKIYLGAAHGYAGILFVLFNLIIFFLDHINELCLSLIGENNDIGEDGRKEKLEKCKDLTTDKLNNYIKLIYKVTDEILSLYVTDDFNVYSSIRKEKIQKKKEILIQWCHGNPGFIILLIELLKYEKVPNYFQNKYSNQFIEKMGLLIWEKGLLSKGLGLCHGISGNGIIFLYLYNYTKDKIWYIRSLKYALFSIKFFDRFYNLPDRPDSLFEGYAALVVFLSFILKPELNYFLGHDFSKFLVND</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPE6</accession>
    <name>A0A1J1GPE6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Formate-nitrite transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">FNT</name>
        <name evidence="15" type="ORF">PGAL8A_00399700</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(S)-lactate(in) + H(+)(in) = (S)-lactate(out) + H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29415"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16651"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>acetate(out) + H(+)(out) = acetate(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:71803"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>formate(in) + H(+)(in) = formate(out) + H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:80887"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>pyruvate(out) + H(+)(out) = pyruvate(in) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:64720"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homopentamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the FNT transporter (TC 1.A.16) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527114.1">
        <property type="nucleotide sequence ID" value="XM_028670353.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPE6"/>
    <dbReference type="GeneID" id="39732527"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00399700"/>
    <dbReference type="OMA" id="SIRPLVM"/>
    <dbReference type="OrthoDB" id="4829at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015513">
        <property type="term" value="F:high-affinity secondary active nitrite transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015707">
        <property type="term" value="P:nitrite transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000292">
        <property type="entry name" value="For/NO2_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024002">
        <property type="entry name" value="For/NO2_transpt_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00790">
        <property type="entry name" value="fnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30520">
        <property type="entry name" value="FORMATE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30520:SF6">
        <property type="entry name" value="FORMATE_NITRATE FAMILY TRANSPORTER (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01226">
        <property type="entry name" value="Form_Nir_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01006">
        <property type="entry name" value="FORMATE_NITRITE_TP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="90"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="181"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="211"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="258"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG94293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="315" mass="34578" checksum="9448019040AC57B9" modified="2017-02-15" version="1">MPTNTIKYVVDPINVKTACSSEESYIRCVEYGKAKAHYSNLILLGKAILAGAFVGVCAHASGIAGGLFYFHKLREYVGASVSSFVYGFTFPIAFLCIICTGSDLFTGNTLAVTTALLQKKVKILEYLRVMTISFVGNYIGAVSFAFFVSYGSGAFHKNTDISKNHIFQFLNDIAAKKVSHSFVECICLAIGCNIFVCLAVYFVLSIKDGSGLVFSVFFAVYSFAIAGYEHIIANIYTLNLSLMVNTSVSFSDVYFKNLLPTLIGNYIAGACVLAIPLYFIYRNHYINYEKINDELNNAALKTLSIELHNGSNDLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPF1</accession>
    <name>A0A1J1GPF1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00408100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527198.1">
        <property type="nucleotide sequence ID" value="XM_028670447.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPF1"/>
    <dbReference type="GeneID" id="39732611"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00408100"/>
    <dbReference type="OMA" id="FFICQVK"/>
    <dbReference type="OrthoDB" id="364838at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="144" mass="17625" checksum="14CDDC4A9BAC5119" modified="2017-02-15" version="1">MILWKIKKNYFSFKGIRYLSSKKVSNYYVHERPSVKEMDDEYKKFLEIKKKENILSEFKITNIDINTFKKYKHKNNPTFSTEFKIFITGFLIFSWCIFAIYLTIRIMTPDDFEWVENERKRLEDAKKKIMIIKEKELKSVHNQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPK8</accession>
    <name>A0A1J1GPK8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00183300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527262.1">
        <property type="nucleotide sequence ID" value="XM_028670517.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730360"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00183300"/>
    <dbReference type="OMA" id="RDYKMKN"/>
    <dbReference type="OrthoDB" id="372923at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1345"/>
            <end position="1373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="196"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1359"/>
            <end position="1369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1493" mass="177442" checksum="57FB1D42C6793D30" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPQ4</accession>
    <name>A0A1J1GPQ4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00188700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000026">
        <property type="protein sequence ID" value="CRG94492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527310.1">
        <property type="nucleotide sequence ID" value="XM_028670571.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPQ4"/>
    <dbReference type="GeneID" id="39730414"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00188700"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006496">
        <property type="entry name" value="CHP01606_Plasmodium_spp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09688">
        <property type="entry name" value="Wx5_PLAF3D7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012565842" evidence="2">
        <location>
            <begin position="29"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="302" mass="36318" checksum="8737DC1153C0D7D5" modified="2017-02-15" version="1">MKTLILYLKSTTFLLLIWMYQCFYNCDSYKTLIGENILQKENKLKYERILTEGDITAKNQAYAEVYTEECPLDNKKNKCEDPFQYENPCDHWNNVIAPRMLELFNKETSGMDPKWRDQKWKNEWNNISSKKVNDLSSISHRHDISEEEKKKLIDSVMEELFSEFVKFLDECEKEIIDNKTGSVCKKEMRDNKIESKCKNEMRDNKTKSESKKEIRDNNTESEFKKEMKDNKTECEFKKEMKDNKTESEFKKEMKDNKTECEFKKQMKDNKTESESKNEQGENKIKNKKLNIWKFLINMFDNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPQ9</accession>
    <name>A0A1J1GPQ9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Kinesin-5, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">KLP3</name>
        <name evidence="12" type="ORF">PGAL8A_00398800</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527105.1">
        <property type="nucleotide sequence ID" value="XM_028670343.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732518"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00398800"/>
    <dbReference type="OMA" id="DDNKMDQ"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005876">
        <property type="term" value="C:spindle microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008574">
        <property type="term" value="F:plus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090307">
        <property type="term" value="P:mitotic spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051231">
        <property type="term" value="P:spindle elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047149">
        <property type="entry name" value="KIF11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47970:SF12">
        <property type="entry name" value="KINESIN FAMILY MEMBER 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47970">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KIF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6 8" id="KW-0505">Motor protein</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="11">
        <location>
            <begin position="15"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1369"/>
            <end position="1396"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="434"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="918"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="1049"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="1385"/>
            <end position="1396"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="100"/>
            <end position="107"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG94284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1396" mass="164387" checksum="89E250DB0C00CD98" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPT6</accession>
    <name>A0A1J1GPT6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fam-b protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00185000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000024">
        <property type="protein sequence ID" value="CRG94458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527279.1">
        <property type="nucleotide sequence ID" value="XM_028670537.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPT6"/>
    <dbReference type="GeneID" id="39730377"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00185000"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011955585" description="Fam-b protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="157" mass="18795" checksum="2C03762282B57418" modified="2017-02-15" version="1">MKKLFLKVILFDIPLILFGLCNGGNNGRELNNLEDLIINTPIDFHLENRNNKEDIDKFSYNYDLREDYYNKIRDNVRTESKIPSDLSKNILYKNIRGNSEENETHNEILKIPFIRMYKNKLYIQQRKLLNMKNKLNDIHMTLSDRISKFFIIPEPQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPV4</accession>
    <name>A0A1J1GPV4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-f protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00187200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000025">
        <property type="protein sequence ID" value="CRG94477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527295.1">
        <property type="nucleotide sequence ID" value="XM_028670554.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPV4"/>
    <dbReference type="GeneID" id="39730399"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00187200"/>
    <dbReference type="OMA" id="VDAYINI"/>
    <dbReference type="OrthoDB" id="1490254at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="595" mass="71590" checksum="27BF85BE79B9642F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ34</accession>
    <name>A0A1J1GQ34_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TRAP-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00201800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527436.1">
        <property type="nucleotide sequence ID" value="XM_028670711.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730544"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00201800"/>
    <dbReference type="OMA" id="HKDDQVH"/>
    <dbReference type="OrthoDB" id="378224at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012000759" evidence="3">
        <location>
            <begin position="21"/>
            <end position="4294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="4227"/>
            <end position="4246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="438"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="588"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="954"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1223"/>
            <end position="1302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1383"/>
            <end position="1758"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1830"/>
            <end position="2075"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2104"/>
            <end position="2344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2378"/>
            <end position="2473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2503"/>
            <end position="3018"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3077"/>
            <end position="3422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3434"/>
            <end position="3516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3549"/>
            <end position="3569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3617"/>
            <end position="3640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3785"/>
            <end position="3947"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3975"/>
            <end position="4015"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="438"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="527"/>
            <end position="536"/>
        </location>
    </feature>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQB1</accession>
    <name>A0A1J1GQB1_PLAGA</name>
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    <organism evidence="2 3">
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        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527275.1">
        <property type="nucleotide sequence ID" value="XM_028670531.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQB1"/>
    <dbReference type="GeneID" id="39730373"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00184600"/>
    <dbReference type="OMA" id="IHINDIC"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="287" mass="33266" checksum="56EB15B7528BEFE6" modified="2017-02-15" version="1">MNGGKQVIGEETREHGKQEISKETKYPNSQDEKINENDITKETINNDQNKKGILINEHQKISDNVSGVNNEIDKIIREHGKQDKKMKNDDDIEETFHSDQKKNDKLTNEHQSGDNMNGGKHEISKTTKDPNSQVVKINENDTTKDTINNDQNKKGTLINEHQKTSDNVSGVNNEIDKIIREHGKQDKEMNNGDNKEEEIFHFDQNKNDKLTNEHQTYDNIDREKQEISKTIKDPNSPDEKINENDITKKTINNDQNNNDSLKVLKSDKNKKKIKIYAYFIKVRIQFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQC1</accession>
    <name>A0A1J1GQC1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ATP-dependent RNA helicase DBP10, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00120200</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526317.1">
        <property type="nucleotide sequence ID" value="XM_028674714.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQC1"/>
    <dbReference type="GeneID" id="39729727"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00120200"/>
    <dbReference type="OMA" id="KYHILFF"/>
    <dbReference type="OrthoDB" id="10261375at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF8">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="10">
        <location>
            <begin position="154"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="186"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="387"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="541"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="803"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="868"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="154"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG93495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1161" mass="136337" checksum="4DBD010DF719DA10" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQH7</accession>
    <name>A0A1J1GQH7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">FYVE and coiled-coil domain-containing protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">FCP</name>
        <name evidence="7" type="ORF">PGAL8A_00219400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527612.1">
        <property type="nucleotide sequence ID" value="XM_028670906.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQH7"/>
    <dbReference type="GeneID" id="39730721"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00219400"/>
    <dbReference type="OMA" id="QKNMNIK"/>
    <dbReference type="OrthoDB" id="79871at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052113">
        <property type="entry name" value="FYVE-type_Zinc_Finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39490">
        <property type="entry name" value="ARRESTIN DOMAIN-CONTAINING PROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39490:SF8">
        <property type="entry name" value="ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01363">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50178">
        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="6">
        <location>
            <begin position="34"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="164"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG94797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="324" mass="37961" checksum="55AB5BA38A1A3C42" modified="2017-02-15" version="1">MGNSTENDCYITPSTSFNGDVENENEKKLFWVPDEEVTNCYSCNVFFNVRIRKHHCRACGNVFCSNCSDNKLKISEYYYAEKVRVCDRCFIERSSPQTLLLQEDLGARKQINQDLKKALSEKMAIVERFKTFLIEFDSEILNNNNYQEDSTDVISLLKRGEKGLKILNDKIKNYDTVIEKQKNELEQLKKEKEQKIELNKILNLKNQEILQKNMNIKNLLKEKNDLILVKEESEDIIELYKKQVEKLIIRCNKLEMEKKSRSKSENNNYSFTKTSNATSSSYFQNSYSTPQNEMCLSYTVADGPSENVEENCCNRCQRRICFIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQR7</accession>
    <name>A0A1J1GQR7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Heat shock protein 90, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">HSP90</name>
        <name evidence="6" type="ORF">PGAL8A_00203100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527449.1">
        <property type="nucleotide sequence ID" value="XM_028670725.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQR7"/>
    <dbReference type="GeneID" id="39730557"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00203100"/>
    <dbReference type="OrthoDB" id="28737at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16927">
        <property type="entry name" value="HATPase_Hsp90-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.80:FF:000007">
        <property type="entry name" value="Heat shock protein 90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11260:FF:000007">
        <property type="entry name" value="Heat shock protein 90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.790">
        <property type="entry name" value="Heat shock protein 90, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00505">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019805">
        <property type="entry name" value="Heat_shock_protein_90_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037196">
        <property type="entry name" value="HSP90_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001404">
        <property type="entry name" value="Hsp90_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020575">
        <property type="entry name" value="Hsp90_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003555">
        <property type="entry name" value="PRK05218.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11528">
        <property type="entry name" value="HEAT SHOCK PROTEIN 90 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00183">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00775">
        <property type="entry name" value="HEATSHOCK90"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110942">
        <property type="entry name" value="HSP90 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00298">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="816"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="867"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="821"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="867"/>
            <end position="897"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG94634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="906" mass="105344" checksum="56B148DBDB6DA4B7" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQW8</accession>
    <name>A0A1J1GQW8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00233200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527748.1">
        <property type="nucleotide sequence ID" value="XM_028671057.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQW8"/>
    <dbReference type="GeneID" id="39730859"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00233200"/>
    <dbReference type="OMA" id="FPLIWKA"/>
    <dbReference type="OrthoDB" id="376937at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="55"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="119" mass="12938" checksum="C786557A56F944ED" modified="2017-02-15" version="1">MPIEIPLVLSSAFPLIWKAGVAQLSFAKAGGSLAALKGSSILLSKVASTGKSGLLASTSSQLDNIKEAAQKLVEEIEKNVNLSLLFYNIDDEETAGYYLMKKREEYEKLNMFHENGEIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR48</accession>
    <name>A0A1J1GR48_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GPI-anchored micronemal antigen, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00122100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526336.1">
        <property type="nucleotide sequence ID" value="XM_028674735.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR48"/>
    <dbReference type="GeneID" id="39729746"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00122100"/>
    <dbReference type="OrthoDB" id="377662at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013085605" evidence="3">
        <location>
            <begin position="22"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="730"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="347"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="347"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="436"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="751" mass="85704" checksum="CC81A91A5A090B55" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR88</accession>
    <name>A0A1J1GR88_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Inner membrane complex protein 1j, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ALV7</name>
        <name evidence="1" type="ORF">PGAL8A_00149900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526613.1">
        <property type="nucleotide sequence ID" value="XM_028675042.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR88"/>
    <dbReference type="GeneID" id="39730023"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00149900"/>
    <dbReference type="OMA" id="VNPTIEY"/>
    <dbReference type="OrthoDB" id="390934at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022086">
        <property type="entry name" value="IMCp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12314">
        <property type="entry name" value="IMCp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="532" mass="61224" checksum="078B4C9CC87A795A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRE4</accession>
    <name>A0A1J1GRE4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cyclin-dependent kinase 2 homolog</fullName>
            <ecNumber evidence="3">2.7.11.22</ecNumber>
            <ecNumber evidence="2">2.7.11.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Cell division control protein 2 homolog</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">cdc2-related kinase 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="primary">PK6</name>
        <name evidence="19" type="ORF">PGAL8A_00248000</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10216"/>
            <dbReference type="Rhea" id="RHEA-COMP:11321"/>
            <dbReference type="Rhea" id="RHEA-COMP:11322"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43176"/>
            <dbReference type="ChEBI" id="CHEBI:68546"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.23"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">May form a complex composed of at least the catalytic subunit CRK2 and a cyclin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="3"/>
    <dbReference type="EC" id="2.7.11.23" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527894.1">
        <property type="nucleotide sequence ID" value="XM_028671220.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRE4"/>
    <dbReference type="GeneID" id="39731008"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00248000"/>
    <dbReference type="OMA" id="FLCVIGK"/>
    <dbReference type="OrthoDB" id="1732493at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008353">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000624">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF495">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 16 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 16 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 17" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5 19" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="18">
        <location>
            <begin position="9"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00039612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00041902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00042858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="CRG95081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="285" mass="33272" checksum="A3FEEC140D63DF00" modified="2017-02-15" version="1">MNTSDILNFDFLCIIGKGTYGIVYKALDKKENNFVAIKKIKNLCDENYGINLKYVFYGKDIEEKLKGENLENSCLYLTFEYCDIDLLNFTKKYNLNIKEIKYIIFELLLAISYLHSNNYIHRDIKPENIFINSNGRIKLGDLGMSVEKSNHMTPTVVTLWYRAPEILLKSKSYDQKVDIWSLGCLFMELITGRPLFPGKNDYSQLELIYLTLGDKNKISAEDVDRFNMFPYFEKNIIKNTIPEESIVDLISKMLIYDPNYRISSKEAIKHSCFSDIEKIKFSCNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRG9</accession>
    <name>A0A1J1GRG9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA-3-methyladenine glycosylase II</fullName>
            <ecNumber evidence="4">3.2.2.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">3-methyladenine DNA glycosidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00226500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine.</text>
            <dbReference type="EC" id="3.2.2.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DNA glycosylase MPG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.21" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527683.1">
        <property type="nucleotide sequence ID" value="XM_028670985.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRG9"/>
    <dbReference type="GeneID" id="39730792"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00226500"/>
    <dbReference type="OrthoDB" id="6353017at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003905">
        <property type="term" value="F:alkylbase DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.300.10">
        <property type="entry name" value="Methylpurine-DNA glycosylase (MPG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00527">
        <property type="entry name" value="3MGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011034">
        <property type="entry name" value="Formyl_transferase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003180">
        <property type="entry name" value="MPG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036995">
        <property type="entry name" value="MPG_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10429">
        <property type="entry name" value="DNA-3-METHYLADENINE GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10429:SF0">
        <property type="entry name" value="DNA-3-METHYLADENINE GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02245">
        <property type="entry name" value="Pur_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50486">
        <property type="entry name" value="FMT C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="468" mass="55765" checksum="50AB5E6FB2CDC27D" modified="2017-02-15" version="1">MNMKVEKKQNKSLINKQDIEISNQKDLKQKLNIKKKKIIKEIKILEKKKPIDTFNLAYVYILLKYFFDNNNIDILNEHFYLQDNVLNITEDLIGHILWVFDKNENKLYGSRIIELESYNGAKDKASHAYNNKKTNRNLSMFEKGGRSYVYICYGIHNCLNIVTNLENIPEAILIRSLEPIYNIEYFISNKFKNTSENLYFENFFENDRGYKVEDKEYMKKRKNDIKDLINKENYLKKIDKVDNVLKMINKKKLVKLCSGPGCVTKCLKVTRQDDMEYFYIDLLNNNIKKEDKLKKEVNYNKNMMISINYNDNNKSSKYFNNSKLLNDKGKSKKKNIDGINVSNKNNSSSNILLHDSSKNIKSNYYFSSNINNLEKSRFFISICPTVNDILYFYETLRADKNEEEYIIKNIYDDNKMYLLEYFDYMKWQKDKLIIQKDKRIGINYAEEAALYEYRFLLKNHPSVTFPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRQ8</accession>
    <name>A0A1J1GRQ8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Apicoplast ribosomal protein L18, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00142000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526536.1">
        <property type="nucleotide sequence ID" value="XM_028674957.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRQ8"/>
    <dbReference type="GeneID" id="39729944"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00142000"/>
    <dbReference type="OMA" id="NRVVNNG"/>
    <dbReference type="OrthoDB" id="309483at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008097">
        <property type="term" value="F:5S rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00432">
        <property type="entry name" value="Ribosomal_L18_L5e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057268">
        <property type="entry name" value="Ribosomal_L18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005484">
        <property type="entry name" value="Ribosomal_uL18_bac/plant/anim"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12899">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L18, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12899:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL18M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00861">
        <property type="entry name" value="Ribosomal_L18p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53137">
        <property type="entry name" value="Translational machinery components"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="207" mass="23904" checksum="106A506DBA6F6BD1" modified="2017-02-15" version="1">MYISFIIFPLFLVYLGVLEGFIINRNIFHNYNNFLLLASSKKKKNTIEEAPKRKNKNIKEKKKKNKILETLLKEKVEKVKVNLDYSGSQNVDKEILEGKRVPRLRIKKTNNHIYATIVDDYKRHVLCFSCSHDSTLSQILGTYRKKTTNRIINNGKTIKAAWEIGKIVAKKALNKGIFKVKFDRANYKYEGRVEALAEGARAVGLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRT2</accession>
    <name>A0A1J1GRT2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00262200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0587 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528030.1">
        <property type="nucleotide sequence ID" value="XM_028671371.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRT2"/>
    <dbReference type="GeneID" id="39731151"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00262200"/>
    <dbReference type="OMA" id="NWCDYNQ"/>
    <dbReference type="OrthoDB" id="10248838at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008584">
        <property type="entry name" value="CXXC_Zn-binding_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12857">
        <property type="entry name" value="CXXC MOTIF CONTAINING ZINC BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12857:SF0">
        <property type="entry name" value="CXXC MOTIF CONTAINING ZINC BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05907">
        <property type="entry name" value="CXXC_Zn-b_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141678">
        <property type="entry name" value="MAL13P1.257-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="155" mass="18487" checksum="67BF0A35F18CB90E" modified="2017-02-15" version="1">MKNTTIRIKAELENVKRLYCDDEYLWIFNIRDSSSSLTRDNIQFRKIDKLDIPNSRGTANFMVKWTEYPKYSTINFVNTKNCCSYGEESNIWKDFASFECRGIEIVDFIPSNNFIVEDTKGKLYYDVNLSEFNWCDYNEENEMCVGIYNLEYEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRX9</accession>
    <name>A0A1J1GRX9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Exportin-1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00002200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the exportin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528068.1">
        <property type="nucleotide sequence ID" value="XM_028671413.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRX9"/>
    <dbReference type="GeneID" id="39728544"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00002200"/>
    <dbReference type="OMA" id="WAFKHNN"/>
    <dbReference type="OrthoDB" id="27218at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005049">
        <property type="term" value="F:nuclear export signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006611">
        <property type="term" value="P:protein export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000056">
        <property type="term" value="P:ribosomal small subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041235">
        <property type="entry name" value="Exp1_repeat_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013598">
        <property type="entry name" value="Exportin-1/Importin-b-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045065">
        <property type="entry name" value="XPO1/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014877">
        <property type="entry name" value="XPO1_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040485">
        <property type="entry name" value="XPO1_repeat_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11223">
        <property type="entry name" value="EXPORTIN 1/5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11223:SF2">
        <property type="entry name" value="EXPORTIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08767">
        <property type="entry name" value="CRM1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18784">
        <property type="entry name" value="CRM1_repeat_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18787">
        <property type="entry name" value="CRM1_repeat_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08389">
        <property type="entry name" value="Xpo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01102">
        <property type="entry name" value="CRM1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="7">
        <location>
            <begin position="45"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="881"/>
            <end position="908"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1228" mass="144811" checksum="015F8D4F6006C6A4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS74</accession>
    <name>A0A1J1GS74_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PI31 proteasome regulator N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00386400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome inhibitor PI31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526981.1">
        <property type="nucleotide sequence ID" value="XM_028670206.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS74"/>
    <dbReference type="GeneID" id="39732394"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00386400"/>
    <dbReference type="OrthoDB" id="370646at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004866">
        <property type="term" value="F:endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1000.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045128">
        <property type="entry name" value="PI31-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021625">
        <property type="entry name" value="PI31_Prot_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13266">
        <property type="entry name" value="PROTEASOME INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13266:SF1">
        <property type="entry name" value="PROTEASOME INHIBITOR PI31 SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11566">
        <property type="entry name" value="PI31_Prot_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0647">Proteasome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PI31 proteasome regulator N-terminal" evidence="3">
        <location>
            <begin position="20"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="283" mass="33357" checksum="8F2104B3721393CB" modified="2017-02-15" version="1">MKMRVHNTFKDLIKFNDNLKKEEILILFFHSSILDHNFIYELEDKKKSLIIENENMKISEGYIRYIADNNKEKVFIGRILIDPEWRKNSNNYNFIYKNHENNNRYILNISKIDNSLVLHVINISEPSSIHSVTIKINEYIKNNNEINIENIEESIKIQKLENIFQTHILGNMKFNHNSNVASTNLINKFNVNELPNPKNNIRQDSHFIKNFNDDNFDDKNPVIRESILPNYIKQIPILKPDGLLVGPNNRFFDPKNLRYDPIGPFGLEPNADTPTKFPDNFPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSB8</accession>
    <name>A0A1J1GSB8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">6-cysteine protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">P47</name>
        <name evidence="11" type="ORF">PGAL8A_00257900</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cell surface</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527987.1">
        <property type="nucleotide sequence ID" value="XM_028671324.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSB8"/>
    <dbReference type="GeneID" id="39731107"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00257900"/>
    <dbReference type="OMA" id="DFALNPH"/>
    <dbReference type="OrthoDB" id="392220at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2860">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010884">
        <property type="entry name" value="6_CYS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038160">
        <property type="entry name" value="6_CYS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07422">
        <property type="entry name" value="s48_45"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00970">
        <property type="entry name" value="s48_45"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51701">
        <property type="entry name" value="6_CYS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009618936" evidence="9">
        <location>
            <begin position="17"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="411"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="10">
        <location>
            <begin position="24"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="10">
        <location>
            <begin position="278"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG95174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="430" mass="49638" checksum="B5301ABB970DE663" modified="2017-02-15" version="1">MKFLVSVLFFIYFINSFRVNGINHLFMCDFYFNPAKSIKPILVGKHDETEEVGCTINNPILGEIVFLICPKRKEGDYENMELVPSNCFASHLYSPYTAGKNEKDIEKLDIDKKYTHSFSYDDYEIKTFRVPSIYKHNKTIYCRCDNRKTEKEHNDKEKFQGKTGLVKIILSEKIDNSNILDFTDSNISKNKNIKVNGTNYEIDLVENNIFSARIENIKDGNFENCNDMLYVKFNKIDENDFSIRTPTIFFEDINCKATFISTENKTFTIVMKASKTENIEGCDFTKPNGDGIYKHGFVLNDISDNEKICTAYIGSSKKKIVAGIKCPYKLIPTYCFRHVLYEKEISGNKVFKTFLLEDILGFRDIEYYSNINNGSYIVGLPIKSERYAAVRCICENNGKRGIMELKIASSYTSFISFILLFITIILLYLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSI7</accession>
    <name>A0A1J1GSI7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">EH (Eps15 homology) protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00003500</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Endosome membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528081.1">
        <property type="nucleotide sequence ID" value="XM_028671428.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSI7"/>
    <dbReference type="GeneID" id="39728557"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00003500"/>
    <dbReference type="OMA" id="LMIGQYS"/>
    <dbReference type="OrthoDB" id="1716625at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00052">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09913">
        <property type="entry name" value="EHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000147">
        <property type="entry name" value="EH domain-containing protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.268.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040990">
        <property type="entry name" value="DUF5600"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000261">
        <property type="entry name" value="EH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031692">
        <property type="entry name" value="EHD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216:SF31">
        <property type="entry name" value="AT21416P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216">
        <property type="entry name" value="EH DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18150">
        <property type="entry name" value="DUF5600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12763">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16880">
        <property type="entry name" value="EHD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00027">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50031">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="10">
        <location>
            <begin position="52"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="EH" evidence="9">
        <location>
            <begin position="441"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG95270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="525" mass="61420" checksum="926D27D7C7BE6A76" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSM4</accession>
    <name>A0A1J1GSM4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00267500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000036">
        <property type="protein sequence ID" value="CRG95472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528282.1">
        <property type="nucleotide sequence ID" value="XM_028671651.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSM4"/>
    <dbReference type="GeneID" id="39731204"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00267500"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006496">
        <property type="entry name" value="CHP01606_Plasmodium_spp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09688">
        <property type="entry name" value="Wx5_PLAF3D7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013017921" evidence="2">
        <location>
            <begin position="29"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="250" mass="29819" checksum="68D04E470B75754E" modified="2017-02-15" version="1">MKTLILYLKITSFLLLIWMYPCFNKCNSYKTLIDKNILEAKNELKYERLLAEGDIADKKQTKAEGGLEECALDNKKNEYKNPVQYENPCDHWHNVVTPILRKQFDEETSEMDPKWRDQKWNNEWNNISSTKVNDLSSIYQQQDISEEEKKKKIFSVMEEISSEFAKFLDECKKEIKNNKTESKSKKEMRDNKTESESMKEMKNNKIESKSMKEMIDNKTESESKNEQGKNKIKNKKSNFLKFLFKRFDNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSN2</accession>
    <name>A0A1J1GSN2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP-dependent Clp protease proteolytic subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ClpP</name>
        <name evidence="9" type="ORF">PGAL8A_00006800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>Hydrolysis of proteins to small peptides in the presence of ATP and magnesium. alpha-casein is the usual test substrate. In the absence of ATP, only oligopeptides shorter than five residues are hydrolyzed (such as succinyl-Leu-Tyr-|-NHMec, and Leu-Tyr-Leu-|-Tyr-Trp, in which cleavage of the -Tyr-|-Leu- and -Tyr-|-Trp bonds also occurs).</text>
            <dbReference type="EC" id="3.4.21.92"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase S14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528113.1">
        <property type="nucleotide sequence ID" value="XM_028671463.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSN2"/>
    <dbReference type="GeneID" id="39728590"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00006800"/>
    <dbReference type="OMA" id="LENYGCE"/>
    <dbReference type="OrthoDB" id="1721884at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009368">
        <property type="term" value="C:endopeptidase Clp complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051117">
        <property type="term" value="F:ATPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07017">
        <property type="entry name" value="S14_ClpP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00444">
        <property type="entry name" value="ClpP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033135">
        <property type="entry name" value="ClpP_His_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381:SF11">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00382">
        <property type="entry name" value="CLP_PROTEASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013266810" description="ATP-dependent Clp protease proteolytic subunit" evidence="8">
        <location>
            <begin position="21"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG95302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="336" mass="39049" checksum="F5382EEFF39AF089" modified="2017-02-15" version="1">MIYLLLFLFFILLRKSEIQSKKSFKKLNILNFIPFPNKNLITKRIEKEILNSSLKKNEDNIIICKEKRNISNLSNISKSSKEIKKKSVLNNLENYGCENGMKNFKNDKQDIVKQDENIISENNNVIGKKKKKKKSYKKVQNIMPTNDIKDLKKDIKLFFFKKRIIYITDEINKKTADEIISQLLYLDNLNHDDIKIYINSPGGSINEGLAILDIFNYIKSDIQTISFGLVASMASVILASGKKGKRKSLPNCRIMIHQPLGNAFGHPHDIEIQTKEILYLKSLLYNYLSRFTNQSIETIEKHSDRDFYMNALEAKNYGIIDEIIETKLPHPYFNEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSR1</accession>
    <name>A0A1J1GSR1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CCT-beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">CCT2</name>
        <name evidence="11" type="ORF">PGAL8A_00006100</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528107.1">
        <property type="nucleotide sequence ID" value="XM_028671457.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSR1"/>
    <dbReference type="GeneID" id="39728583"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00006100"/>
    <dbReference type="OMA" id="CAEMVMS"/>
    <dbReference type="OrthoDB" id="10248520at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03336">
        <property type="entry name" value="TCP1_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000002">
        <property type="entry name" value="T-complex protein 1 subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000017">
        <property type="entry name" value="T-complex protein 1 subunit eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012716">
        <property type="entry name" value="Chap_CCT_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02341">
        <property type="entry name" value="chap_CCT_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG95296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="532" mass="58989" checksum="A5AD06903454AD20" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSW2</accession>
    <name>A0A1J1GSW2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Endonuclease, putative</fullName>
            <ecNumber evidence="5">4.2.99.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00384300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.18" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526960.1">
        <property type="nucleotide sequence ID" value="XM_028670182.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSW2"/>
    <dbReference type="GeneID" id="39732373"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00384300"/>
    <dbReference type="OrthoDB" id="1937206at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008409">
        <property type="term" value="F:5'-3' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006086">
        <property type="entry name" value="XPG-I_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081:SF9">
        <property type="entry name" value="FLAP ENDONUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081">
        <property type="entry name" value="FLAP ENDONUCLEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00867">
        <property type="entry name" value="XPG_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00853">
        <property type="entry name" value="XPGRADSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00484">
        <property type="entry name" value="XPGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XPG-I" evidence="4">
        <location>
            <begin position="230"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="385" mass="45324" checksum="7C3E1A78BF7F3051" modified="2017-02-15" version="1">MTIKGLIRFINKKIPNTIKKIDDIKSFKGKKFIIDGTFFIYKFMYVAWKHILNDKNRENKYKNNEIATHILIRQYIIKKSIELLKNQHEYFKSLKINTLYIIEDIGARSELQPIDYKCKKHVWKERDLIRKKKNLFDILNIDASKKCNSKNTESLNDNTLNNCHIKKNINMNKFLNDKKSNICNVCEKKNLKKCKMEIVVDEDGVHDLFKKNIFIKINSKTANDIYNYLLLEKIPIFITKNDAEKECAIQCSHEKDIVVSDDTDALAFGAPNLIRFITNKKKRHIINKEELLSELNINYEQFIDFCILSGCDYSAKIPGIGPVKAHEIIKKYKTIETFLESKAFNKYKNSKLFNEKLNGISMSLNDYIINEFTYEQARKVFFNSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSX5</accession>
    <name>A0A1J1GSX5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00179700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527229.1">
        <property type="nucleotide sequence ID" value="XM_028670481.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730324"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00179700"/>
    <dbReference type="OMA" id="TIMTANI"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="660"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="262"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="311"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="433"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1341"/>
            <end position="1371"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="121"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1122"/>
            <end position="1170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="268"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="317"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="433"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1349"/>
            <end position="1371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1554" mass="182607" checksum="70B2E904832600D1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSZ4</accession>
    <name>A0A1J1GSZ4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Merozoite surface protein 4, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">MSP4</name>
        <name evidence="5" type="ORF">PGAL8A_00017500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528217.1">
        <property type="nucleotide sequence ID" value="XM_028671579.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSZ4"/>
    <dbReference type="GeneID" id="39728697"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00017500"/>
    <dbReference type="OMA" id="NIFCAKR"/>
    <dbReference type="OrthoDB" id="10060424at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024731">
        <property type="entry name" value="NELL2-like_EGF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12947">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="5" id="KW-0477">Merozoite</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EGF-like" evidence="4">
        <location>
            <begin position="185"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="46"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="66"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="144"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="225" mass="23493" checksum="67200BCC0C56D716" modified="2017-02-15" version="1">MNIIKFLSATNFFIFLSLYFEKSSINFSNDLSNNNVLTLKRFLTQSPTSAGSSNDGSAGTASVQNTGSGTDSGTDSGTDSGTGGAVKVTGAVPAEVPASSSPAEPKSGAKGSTEPRRKGKQRRQNESEATSGDDITLQQKDTESEGDSPASEDDGEEDEDLCADNNGGCSSDQICESLGGGRVKCICTEGFKLVNNKCVKISESSSLNSIFSICLFFFLTLSVIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT24</accession>
    <name>A0A1J1GT24_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00016900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528211.1">
        <property type="nucleotide sequence ID" value="XM_028671572.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728691"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00016900"/>
    <dbReference type="OMA" id="KWEFFEE"/>
    <dbReference type="OrthoDB" id="419768at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010828">
        <property type="term" value="P:positive regulation of D-glucose transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090314">
        <property type="term" value="P:positive regulation of protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031340">
        <property type="term" value="P:positive regulation of vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072659">
        <property type="term" value="P:protein localization to plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038983">
        <property type="entry name" value="C2CD5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057815">
        <property type="entry name" value="C2CD5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056431">
        <property type="entry name" value="C2CD5_YbjQ-rel_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035439">
        <property type="entry name" value="UPF0145_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37412">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37412:SF2">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23025">
        <property type="entry name" value="YbjQ_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23128">
        <property type="entry name" value="YbjQ_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117782">
        <property type="entry name" value="YbjQ-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="3">
        <location>
            <begin position="256"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="3">
        <location>
            <begin position="405"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="C2CD5 C-terminal" evidence="4">
        <location>
            <begin position="1428"/>
            <end position="1516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="657"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="775"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="875"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1117"/>
            <end position="1145"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1067"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="665"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="895"/>
            <end position="912"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1517" mass="178644" checksum="7002D43FC5EBF1BD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTJ8</accession>
    <name>A0A1J1GTJ8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Chromatin assembly factor 1 P55 subunit, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00304800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528644.1">
        <property type="nucleotide sequence ID" value="XM_028672052.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTJ8"/>
    <dbReference type="GeneID" id="39731581"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00304800"/>
    <dbReference type="OMA" id="MPQNPDV"/>
    <dbReference type="OrthoDB" id="427795at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022052">
        <property type="entry name" value="Histone-bd_RBBP4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050459">
        <property type="entry name" value="WD_repeat_RBAP46/RBAP48/MSI1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22850">
        <property type="entry name" value="WD40 REPEAT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12265">
        <property type="entry name" value="CAF1C_H4-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Histone-binding protein RBBP4-like N-terminal" evidence="7">
        <location>
            <begin position="31"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="187"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="426" mass="49786" checksum="B2D83AB7FDD98C9B" modified="2017-02-15" version="1">MKKQGNNLSTLNDINNQNEESQHNYLNSNLDNYKYWQYNTILLYNVIMIYTCEWPSLFIEWLPNVYKSDEDYYYQDLILGTYTTEKNNYILILEVSLPSEQFSFSSFYYEKINDYRHNFCNDTSKNFKIKNKIYHECEINKISCNPKNSDVIACFSSDGNINILNLANYQYEENELKKNIGNFDFILKGHLYQGWGLQWDEENDLISSCADDSYLCIWDINSGKKVVNPLMKFFNNNIPLQDCCWKDKNVLTVSENGYINIYDIRSKNLVNSIKATNFTLNSIDINPHNRNIFATAGTNKEIDLWDIRCTSKSLHRIISQKETIIKLKWDKYQPGILSSSSSDKYIYFFDTNKIGIEQTYEDSQDGPPELIFIHGGHSSNILDFSLNTSYSMMISSISEDNTLHIWQPSKQAFEDASDTYDDTEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTW2</accession>
    <name>A0A1J1GTW2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Hemolysin III, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">HlyIII</name>
        <name evidence="8" type="ORF">PGAL8A_00214700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ADIPOR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527565.1">
        <property type="nucleotide sequence ID" value="XM_028670853.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTW2"/>
    <dbReference type="GeneID" id="39730674"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00214700"/>
    <dbReference type="OMA" id="RIHQIAF"/>
    <dbReference type="OrthoDB" id="186812at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004254">
        <property type="entry name" value="AdipoR/HlyIII-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855:SF52">
        <property type="entry name" value="ADIPONECTIN RECEPTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855">
        <property type="entry name" value="ADIPOR/PROGESTIN RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03006">
        <property type="entry name" value="HlyIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="156"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="271"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="273"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR604254-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="296" mass="34390" checksum="6E43D2A071327A5D" modified="2017-02-15" version="1">MKKLNLNDYFNLQYYKSVFLSFLKNDNKTSIFNMPLRDHNIDDTVIRSFLKSKDLSENDKKIVELYNDKKISKIMLVKYIGRKDKTWFRGKIHLMLVFLSPIWIFHMLNLSKTLTTKICTSVAILCIFFNFFASFLFHNFEWNPHFFFFIEKLDHFGIFLMISGSSLPVQALLFNKGKLLLFISLQSMSILFGFLCIFCGCFSSGNRFIRTFTFLSAGFLHSVFIKDYFISLYTSELIFLVSLAVLYVIGAVIYSIKKPNVLPGLIGFHELFHFCCLGSALCTFALNCSVIKRNTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTW4</accession>
    <name>A0A1J1GTW4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nrap protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00294200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528545.1">
        <property type="nucleotide sequence ID" value="XM_028671942.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731475"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00294200"/>
    <dbReference type="OMA" id="KICKLWF"/>
    <dbReference type="OrthoDB" id="10251401at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032545">
        <property type="term" value="C:CURI complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034456">
        <property type="term" value="C:UTP-C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006409">
        <property type="term" value="P:tRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005554">
        <property type="entry name" value="NOL6/Upt22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035368">
        <property type="entry name" value="Nrap_D3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17972:SF0">
        <property type="entry name" value="NUCLEOLAR PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17972">
        <property type="entry name" value="NUCLEOLAR RNA-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17404">
        <property type="entry name" value="Nrap_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nrap protein" evidence="2">
        <location>
            <begin position="590"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="653"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="707"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1106"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1328"/>
            <end position="1354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="715"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1106"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1130"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1155"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1334"/>
            <end position="1353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1541" mass="184272" checksum="07874712FE11E5F7" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU66</accession>
    <name>A0A1J1GU66_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00326800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000053">
        <property type="protein sequence ID" value="CRG96052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528860.1">
        <property type="nucleotide sequence ID" value="XM_028672293.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU66"/>
    <dbReference type="GeneID" id="39731798"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00326800"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="183" mass="21978" checksum="098D815428CC8C29" modified="2017-02-15" version="1">MKTLTLYLKITTFLLLIWMYQCFYNCDYYKTWTDKNILQTKHELKYERVLTEGDIADKKQTKAEGCLEECPSYNKKKKKKNRFQYQNPSHGVKKPSLWESFDKKAKEMDPNLRDHEMNIEWKNISRDKVINLSSKIYQQNIPDEGRQILILSDTKDHSELKKLLDVLKKEMRDNKTESESKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUF8</accession>
    <name>A0A1J1GUF8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Succinyl-CoA synthetase alpha subunit, putative</fullName>
            <ecNumber evidence="7">6.2.1.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00335800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the succinate/malate CoA ligase alpha subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.4" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528948.1">
        <property type="nucleotide sequence ID" value="XM_028672391.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUF8"/>
    <dbReference type="GeneID" id="39731888"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00335800"/>
    <dbReference type="OMA" id="VIICITE"/>
    <dbReference type="OrthoDB" id="1664372at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009361">
        <property type="term" value="C:succinate-CoA ligase complex (ADP-forming)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004776">
        <property type="term" value="F:succinate-CoA ligase (GDP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.261:FF:000010">
        <property type="entry name" value="Succinate--CoA ligase [ADP-forming] subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01988">
        <property type="entry name" value="Succ_CoA_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017440">
        <property type="entry name" value="Cit_synth/succinyl-CoA_lig_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033847">
        <property type="entry name" value="Citrt_syn/SCS-alpha_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005810">
        <property type="entry name" value="CoA_lig_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="SUCC_ACL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004230">
        <property type="entry name" value="PRK05678.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01019">
        <property type="entry name" value="sucCoAalpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11117:SF2">
        <property type="entry name" value="SUCCINATE--COA LIGASE [ADP_GDP-FORMING] SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11117">
        <property type="entry name" value="SUCCINYL-COA LIGASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02629">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001553">
        <property type="entry name" value="SucCS_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01798">
        <property type="entry name" value="SCOASYNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="Succinyl-CoA synthetase domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01216">
        <property type="entry name" value="SUCCINYL_COA_LIG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00399">
        <property type="entry name" value="SUCCINYL_COA_LIG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="CoA-binding" evidence="6">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="4">
        <location>
            <position position="241"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001553-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="285" mass="30559" checksum="69DA16EEF332AFA3" modified="2017-02-15" version="1" fragment="single">GSFHTTEALKYGTKMVGGVNPRKKGTLWKSNDNKYTLPVFGSILEAKEQTNCYASVIYVPPEHAKNAIIESIESEIPLIVCITEGICQHDMIEVKNCLNMSKKSTLIGPNCPGIIKPGECKIGIMPSHIHKKGCVGIVSRSGTLTYEGVNQTTKVGLGQSTCIGIGGDPFHGTNFIDCLKLFLEDDETKCILLIGEIGGNAEEQVAEWLIQNNVDDGKRKKKPVFAFIAGKCAPPGKRMGHAGALISGGKGTADEKIEALRSAGVHTITNPTQMGSAIYSIMKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUG0</accession>
    <name>A0A1J1GUG0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00315000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528745.1">
        <property type="nucleotide sequence ID" value="XM_028672164.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731683"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00315000"/>
    <dbReference type="OMA" id="KMKYLIM"/>
    <dbReference type="OrthoDB" id="372946at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="223"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1616"/>
            <end position="1676"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="725"/>
            <end position="1437"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1945"/>
            <end position="1979"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="223"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1619"/>
            <end position="1633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1641"/>
            <end position="1667"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2472" mass="295224" checksum="1DCDD9B09083C782" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUG3</accession>
    <name>A0A1J1GUG3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-hydroxyacyl-[acyl-carrier-protein] dehydratase</fullName>
            <ecNumber evidence="2">4.2.1.59</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">FabZ</name>
        <name evidence="10" type="ORF">PGAL8A_00234900</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.59" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527765.1">
        <property type="nucleotide sequence ID" value="XM_028671075.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUG3"/>
    <dbReference type="GeneID" id="39730877"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00234900"/>
    <dbReference type="OMA" id="KLRGCAY"/>
    <dbReference type="OrthoDB" id="4155at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019171">
        <property type="term" value="F:(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01288">
        <property type="entry name" value="FabZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.129.10:FF:000001">
        <property type="entry name" value="3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00406">
        <property type="entry name" value="FabZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013114">
        <property type="entry name" value="FabA_FabZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010084">
        <property type="entry name" value="FabZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01750">
        <property type="entry name" value="fabZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000582">
        <property type="entry name" value="PRK00006.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30272">
        <property type="entry name" value="3-HYDROXYACYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30272:SF1">
        <property type="entry name" value="3-HYDROXYACYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07977">
        <property type="entry name" value="FabA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012701216" description="3-hydroxyacyl-[acyl-carrier-protein] dehydratase" evidence="9">
        <location>
            <begin position="17"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG94952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="218" mass="24756" checksum="9F3618F29106F8C1" modified="2017-02-15" version="1">MNLFFIFIIVISPILSLDIKKNELFYLSPSSKNYNKNAYFKKYKKNIYLSNETKNDNLTGEYISSKLSYSDYKTIDIEDIKNTLPHRYPFLLVDKVLHIEPNKKIIGVKQVSVNENFFNGHFPEKPIMPGVLQIEALAQLGGVLCLKSEENQKNNLFLFAGVDGVRWKKPVLPGDTLVMEVEQISFKPSLGIAKLRGVGYVNGNVVIKVSEMTFALSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUI8</accession>
    <name>A0A1J1GUI8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">4a-hydroxytetrahydrobiopterin dehydratase</fullName>
            <ecNumber evidence="3">4.2.1.96</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">4-alpha-hydroxy-tetrahydropterin dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00335600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin = (6R)-L-erythro-6,7-dihydrobiopterin + H2O</text>
            <dbReference type="Rhea" id="RHEA:11920"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15642"/>
            <dbReference type="ChEBI" id="CHEBI:43120"/>
            <dbReference type="EC" id="4.2.1.96"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pterin-4-alpha-carbinolamine dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.96" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528946.1">
        <property type="nucleotide sequence ID" value="XM_028672389.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUI8"/>
    <dbReference type="GeneID" id="39731886"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00335600"/>
    <dbReference type="OMA" id="WAEKWNH"/>
    <dbReference type="OrthoDB" id="277398at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008124">
        <property type="term" value="F:4-alpha-hydroxytetrahydrobiopterin dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00488">
        <property type="entry name" value="PCD_DCoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.20">
        <property type="entry name" value="Transcriptional coactivator/pterin dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036428">
        <property type="entry name" value="PCD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001533">
        <property type="entry name" value="Pterin_deHydtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12599">
        <property type="entry name" value="PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12599:SF0">
        <property type="entry name" value="PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01329">
        <property type="entry name" value="Pterin_4a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55248">
        <property type="entry name" value="PCD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="107" mass="13144" checksum="BC190A816E4B3F5E" modified="2017-02-15" version="1">MIIFDKNKINTLIPLWNYKTKKECYNYIERKIRFPSFSQAWKFMNEISKYNEKLNHHCKYINDYNKVKIKIHTHISKDITDKDIKLAHIIDETLKNYEHDTIKEKTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUK6</accession>
    <name>A0A1J1GUK6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00238900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527805.1">
        <property type="nucleotide sequence ID" value="XM_028671121.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUK6"/>
    <dbReference type="GeneID" id="39730917"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00238900"/>
    <dbReference type="OMA" id="RRIHNTH"/>
    <dbReference type="OrthoDB" id="363990at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="400" mass="46817" checksum="0A6784DD65DB7564" modified="2017-02-15" version="1">MQNVENKKIKMKFKLNNIDKKNTLNLNKGKNDINSRYNLNCTNNNTTQNNIISNNKSSLENSNSNNLINNIKINIVSSNSNNNNNNNNTNNNIISNNNNNSSLNGNSNSNNNNSNLLNGNKYILKSNLKIYYKNEIIPFSFLYHKIITILKSHYNNHISNNPVVANKGISFFHLENMLINFGFKGVDINNHFLLSYLASSKQIKIDLNEKRICYINPYIDITNITSLLNKINKYGFLYGYEINDDLINTNKEIYKWVNTLLFEKKVRCIRSNNSHLRGKLKCKNLPTFCDIYSKNKCDNCFYNLKGFIFFPLSYEQIEKERYTITNDIKTLWDEITLPNLDNILKEYKLKSTNNLFLNDNIQKRKTKDDKFAPILKKMKRIYNTHLFTPDEIKNEFIQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUS7</accession>
    <name>A0A1J1GUS7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00351500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529102.1">
        <property type="nucleotide sequence ID" value="XM_028672562.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732045"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00351500"/>
    <dbReference type="OMA" id="ANVSMKK"/>
    <dbReference type="OrthoDB" id="10690721at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="365"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="611"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="750"/>
            <end position="1674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1712"/>
            <end position="1755"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1777"/>
            <end position="1815"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="63"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="299"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="424"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1815"/>
            <end position="1842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="382"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="618"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="750"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="792"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="811"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="828"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="861"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="916"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="940"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="956"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="976"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1046"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1058"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1103"/>
            <end position="1114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1139"/>
            <end position="1156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1157"/>
            <end position="1179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1180"/>
            <end position="1197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1198"/>
            <end position="1211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1219"/>
            <end position="1232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1233"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1245"/>
            <end position="1256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1257"/>
            <end position="1274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1282"/>
            <end position="1292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1293"/>
            <end position="1314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1321"/>
            <end position="1345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1352"/>
            <end position="1394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1395"/>
            <end position="1431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1432"/>
            <end position="1472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1473"/>
            <end position="1628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1638"/>
            <end position="1674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1741"/>
            <end position="1753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1785"/>
            <end position="1815"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1843" mass="223225" checksum="A3EC0645CAE7FA15" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUS9</accession>
    <name>A0A1J1GUS9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00327300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000053">
        <property type="protein sequence ID" value="CRG96057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528865.1">
        <property type="nucleotide sequence ID" value="XM_028672298.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUS9"/>
    <dbReference type="GeneID" id="39731803"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00327300"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="136" mass="16498" checksum="CA89033A2918E911" modified="2017-02-15" version="1">MKAFTLCLKIFTFLILTWIFHCFYNYDSCRSFIDKDTLLINNKLKDKRLLAEGNILEKNQTHIIERKEHYQYGEKDNKNEKLINLKNMYSVYYSAIYLLMCELFFIETNEICSKCKEQMLSFYRSNNSYTKYLEPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUU1</accession>
    <name>A0A1J1GUU1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00247100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527885.1">
        <property type="nucleotide sequence ID" value="XM_028671210.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUU1"/>
    <dbReference type="GeneID" id="39730999"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00247100"/>
    <dbReference type="OMA" id="CIVPIYN"/>
    <dbReference type="OrthoDB" id="376457at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="226"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="410" mass="48698" checksum="EEDAD86A34C7DA73" modified="2017-02-15" version="1">MDKFKESTDNEKNKTNEVKSLSKDFFNQEPKFLNEMKNEESSEKNALTIQNTASYSNEQKENIQNNFNFPKSNTEILKKIENNSNDKLKNNIEKSDLQKNHIGNSLENKFNFGSSLKIRKSLTEQLCEEISMKLGKIFLCKSYLETFIYEKNPYVMNFIYQRDDMSESKNRVLNSLLLSSFSNLVWSNNIYKHEYLLSKEILSKYIKALEKNPDKTNCCIIPIFSLDKIKEVLNDQEKNIRILKKKKLTIKKNNENLLFILNIIKNNFDEIKMKAQRIIQRLLFRLDILDKLFILKNNSVFFSNKYEYNKIKLIEILDFFNSFNIDNKLQKINKNITEIVKEKKNFQKFIYCDNEFSNSLKNNIAKNEQDIIELKSTTSEICINLEENKEHLYHLNHLNVFEGEENYEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV48</accession>
    <name>A0A1J1GV48_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">GPI-anchor transamidase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">GPI8</name>
        <name evidence="7" type="ORF">PGAL8A_00355600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529143.1">
        <property type="nucleotide sequence ID" value="XM_028672607.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV48"/>
    <dbReference type="GeneID" id="39732086"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00355600"/>
    <dbReference type="OMA" id="NCRNIIE"/>
    <dbReference type="OrthoDB" id="192611at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042765">
        <property type="term" value="C:GPI-anchor transamidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003923">
        <property type="term" value="F:GPI-anchor transamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016255">
        <property type="term" value="P:attachment of GPI anchor to protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028361">
        <property type="entry name" value="GPI_transamidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001096">
        <property type="entry name" value="Peptidase_C13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48067">
        <property type="entry name" value="GPI-ANCHOR TRANSAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48067:SF1">
        <property type="entry name" value="GPI-ANCHOR TRANSAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01650">
        <property type="entry name" value="Peptidase_C13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00776">
        <property type="entry name" value="HEMOGLOBNASE"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012204620" evidence="6">
        <location>
            <begin position="21"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="444"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="463" mass="55391" checksum="19CC792D439418A4" modified="2017-02-15" version="1">MELKFFLNFIILFGIKCVTASVNFTGLDIKNIKGKYKELENSAQKHNVNEQFLNELNKSNYKNINVIALSTSRHYFNYRHTSNLLIAYKYLKNLGDIMDKNIILMIPFDQACDCRNIIEGTIFKEYEHFPGESFDEKKENPNLYKNIYIDYKNNNVRDEQIRRVIRHRYDGFTPKKNRLYTSGDKKKNLFIYMTGHGGVNFLKIQEFNIMSSSEFNLYIQELLIKNIYKYIFVIIDTCQGYSFYDDVLKFIYKNKINNVFLLSSSNRTENSYSLFSSKYLSVSTVDRFTYNFFNYLENIYRIYPNEPYKNAKSFSMYNILNYLKTQNIMSEPTINNSKFSSSTFLHDKNILFYNSNFFIINKDFYESPHKYDYMKNKEERLSFQNECLGDLSFCGHIKGNIYTNMINLYNNRSYYSDIKVYMKEETHFADYYFTSKIFDTNNSIKILLALFFILFSILFFFFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVZ7</accession>
    <name>A0A1J1GVZ7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-(apurinic or apyrimidinic site) lyase</fullName>
            <ecNumber evidence="2">4.2.99.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00430000</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66592"/>
            <dbReference type="Rhea" id="RHEA-COMP:13180"/>
            <dbReference type="Rhea" id="RHEA-COMP:16897"/>
            <dbReference type="Rhea" id="RHEA-COMP:17067"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136412"/>
            <dbReference type="ChEBI" id="CHEBI:157695"/>
            <dbReference type="ChEBI" id="CHEBI:167181"/>
            <dbReference type="EC" id="4.2.99.18"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-1 OGG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.18" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529524.1">
        <property type="nucleotide sequence ID" value="XM_028673030.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVZ7"/>
    <dbReference type="GeneID" id="39732832"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00430000"/>
    <dbReference type="OMA" id="ECKIKNG"/>
    <dbReference type="OrthoDB" id="238681at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034039">
        <property type="term" value="F:8-oxo-7,8-dihydroguanine DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006285">
        <property type="term" value="P:base-excision repair, AP site formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="entry name" value="Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012904">
        <property type="entry name" value="OGG_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052054">
        <property type="entry name" value="Oxidative_DNA_repair_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10242">
        <property type="entry name" value="8-OXOGUANINE DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10242:SF2">
        <property type="entry name" value="N-GLYCOSYLASE_DNA LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07934">
        <property type="entry name" value="OGG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55945">
        <property type="entry name" value="TATA-box binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH-GPD" evidence="10">
        <location>
            <begin position="431"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG96720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="658" mass="78995" checksum="7AE151F202E1F305" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWD5</accession>
    <name>A0A1J1GWD5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PIH1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00444800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PIH1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529670.1">
        <property type="nucleotide sequence ID" value="XM_028673192.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWD5"/>
    <dbReference type="GeneID" id="39732981"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00444800"/>
    <dbReference type="OMA" id="SHEHADK"/>
    <dbReference type="OrthoDB" id="5135119at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050734">
        <property type="entry name" value="PIH1/Kintoun_subfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012981">
        <property type="entry name" value="PIH1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22997:SF10">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_56, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22997">
        <property type="entry name" value="PIH1 DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08190">
        <property type="entry name" value="PIH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PIH1 N-terminal" evidence="4">
        <location>
            <begin position="34"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="530"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="409"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="530"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="708" mass="84051" checksum="B55527DE2EC61C86" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWH5</accession>
    <name>A0A1J1GWH5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fam-h protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00448800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529710.1">
        <property type="nucleotide sequence ID" value="XM_028673237.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWH5"/>
    <dbReference type="GeneID" id="39733021"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00448800"/>
    <dbReference type="OMA" id="RYSEHNT"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022139">
        <property type="entry name" value="Fam-L/Fam-M-like_plasmodium"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12420">
        <property type="entry name" value="DUF3671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="186" mass="22073" checksum="A0C77F5A4F68FEBA" modified="2017-02-15" version="1">MYYKKQKIRISLFFKFFIFTLLIWISQYSNNYTCRFLKDKNNFERAINLIYKRTLSEYELIESDEKNLNISDKTNPSDREEESYHNNLNSDYINLINLDNDSEVKLDMRNIKENKKINEHNGGHPIIKLIILSGMFICYIFVVLSCLYKNYYIHNTPNGITQDLFSLLTVTLLLLCSIIIVDRGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWL6</accession>
    <name>A0A1J1GWL6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Actin-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00423500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529459.1">
        <property type="nucleotide sequence ID" value="XM_028672958.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWL6"/>
    <dbReference type="GeneID" id="39732767"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00423500"/>
    <dbReference type="OrthoDB" id="421448at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="538" mass="63677" checksum="01FDBA8CDABFF143" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWN0</accession>
    <name>A0A1J1GWN0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00019000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528232.1">
        <property type="nucleotide sequence ID" value="XM_028671595.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWN0"/>
    <dbReference type="GeneID" id="39728712"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00019000"/>
    <dbReference type="OMA" id="HFTICLN"/>
    <dbReference type="OrthoDB" id="378594at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="522" mass="62064" checksum="EFF836260ABB19EB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWZ0</accession>
    <name>A0A1J1GWZ0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">60S ribosomal protein L14, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00303300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528629.1">
        <property type="nucleotide sequence ID" value="XM_028672036.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWZ0"/>
    <dbReference type="GeneID" id="39731566"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00303300"/>
    <dbReference type="OMA" id="ANWRFVE"/>
    <dbReference type="OrthoDB" id="1875589at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23702">
        <property type="entry name" value="eL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039660">
        <property type="entry name" value="Ribosomal_eL14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002784">
        <property type="entry name" value="Ribosomal_eL14_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11127">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11127:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01929">
        <property type="entry name" value="Ribosomal_L14e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein eL14" evidence="5">
        <location>
            <begin position="65"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="145"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="146"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="156"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="168" mass="19766" checksum="ED18C9C8BDEEA5DB" modified="2017-02-15" version="1">MPRVELTEEEKLNLTKKNLLFKRFVEPGRLCLIEYGPYAGKLCFIVDIITLTRVIVDGAFVTGVPRMIVPIKRLKLLKERIKINKNCKSGFLRKTIKSTNVLEKFKESNLGKKMLIKKRRDLATDYERFKIYYAKRELKKKINFLKNEKERNNKKENKKVKKSSAKGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX24</accession>
    <name>A0A1J1GX24_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Selenoprotein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">Sel2</name>
        <name evidence="2" type="ORF">PGAL8A_00444300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529665.1">
        <property type="nucleotide sequence ID" value="XM_028673186.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732976"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00444300"/>
    <dbReference type="OrthoDB" id="391295at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0711">Selenium</keyword>
    <keyword evidence="2" id="KW-0712">Selenocysteine</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="non-standard amino acid" description="Selenocysteine" evidence="2">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="222" mass="27259" checksum="33736D7E2B68B6A9" modified="2017-02-15" version="1">MKMCYLKFFLKICFLLFLSYDFIYLKSENKKEQGNLFKNGYEIFFVQKDILPSYIKRDNHISIFFCKSUQSQYVLKRIKQYFDILNGEETQLYLENSKFSVDNNKYIIFLMNYKPALIYRLISYFIIFIYILISINVIFPKQSEYFMPSFLINNENYNRIFQEMRKKKLAVFAIMFFSFNIIYGILCNTNVIHIYQNRNLIYNDYYIEHVFIEQLRRNLKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX86</accession>
    <name>A0A1J1GX86_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Actin-1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Actin I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PGAL8A_00466800</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm. Polymerizes into shorter and less stable actin filaments compared to ACT2/actin-2; this is thought to facilitate gliding motility and host cell invasion. Has ATPase activity. ATP hydrolysis leads to the formation of a stable intermediate ADP-inorganic phosphate (Pi) actin, which is followed by the release of Pi. ATP hydrolysis affects filament stability; ADP-bound actin depolymerizes much faster than ATP- or ADP-Pi-bound actin. Plays an essential role during the asexual blood stage. At the segmented schizont stage, required for apicoplast migration and segregation into individual daughter merozoites. Also, required for the separation of daughter merozoites in the final stages of cytokinesis. Essential for merozoite invasion of, but not adhesion to or reorientation towards, host erythrocytes.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">Monomer (G-actin). Oligomer (F-actin). Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Unlike for mammalian monomeric actin, parasite monomeric actin is able to induce oligomerization in the presence of ATP or ADP. Mg(2+), which is used to coordinate ATP, is required for polymerization. Interacts with MyoA. Interacts with DNase I with low affinity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529890.1">
        <property type="nucleotide sequence ID" value="XM_028673438.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX86"/>
    <dbReference type="GeneID" id="39733201"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00466800"/>
    <dbReference type="OMA" id="FHTTAER"/>
    <dbReference type="OrthoDB" id="422673at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10224">
        <property type="entry name" value="ASKHA_NBD_actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000205">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000001">
        <property type="entry name" value="Actin, muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000018">
        <property type="entry name" value="Actin-like protein (Centractin)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000404">
        <property type="entry name" value="Major actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000058">
        <property type="entry name" value="Putative actin-related protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00406">
        <property type="entry name" value="ACTINS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00432">
        <property type="entry name" value="ACTINS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00060256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00062163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00074755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00075592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="CRG97087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="376" mass="41857" checksum="1C5227360E472696" modified="2017-02-15" version="1">MGDEDVQALVVDNGSGNVKAGVAGDDAPRSVFPSIVGRPKNPGIMVGMEEKDAFVGDEAQTKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRAAPEEHPVLLTEAPLNPKGNRERMTQIMFESFNVPAMYVAIQAVLSLYSSGRTTGIVLDSGDGVSHTVPIYEGYALPHAIMRLDLAGRDLTEYLMKILHERGYGFSTSAEKEIVRDIKEKLCYIALNFDEEMKTSEQSSDIEKSYELPDGNIITVGNERFRCPEALFQPSFLGKEAAGIHTTTFNSIKKCDVDIRKDLYGNIVLSGGTTMYEGIGERLTRDITTLAPSTMKIKVVAPPERKYSVWIGGSILSSLSTFQQMWITKEEYDESGPSIVHRKCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX95</accession>
    <name>A0A1J1GX95_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mini-chromosome maintenance complex-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00283700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528448.1">
        <property type="nucleotide sequence ID" value="XM_028671835.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX95"/>
    <dbReference type="GeneID" id="39731370"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00283700"/>
    <dbReference type="OrthoDB" id="329666at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019140">
        <property type="entry name" value="MCM_complex-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13489">
        <property type="entry name" value="MINI-CHROMOSOME MAINTENANCE COMPLEX-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13489:SF0">
        <property type="entry name" value="MINI-CHROMOSOME MAINTENANCE COMPLEX-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09739">
        <property type="entry name" value="MCM_bind"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="87"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="895" mass="106995" checksum="9B9D2677CE72DD6B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXK2</accession>
    <name>A0A1J1GXK2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ankyrin, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00294900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528552.1">
        <property type="nucleotide sequence ID" value="XM_028671950.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXK2"/>
    <dbReference type="GeneID" id="39731482"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00294900"/>
    <dbReference type="OMA" id="NERANEW"/>
    <dbReference type="OrthoDB" id="409391at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="612"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="646"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="679"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="713"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="850"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="154"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="935" mass="111400" checksum="A3861CBE5CF9CD22" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXP4</accession>
    <name>A0A1J1GXP4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">WW domain-binding protein 11, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00299600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528592.1">
        <property type="nucleotide sequence ID" value="XM_028671995.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXP4"/>
    <dbReference type="GeneID" id="39731529"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00299600"/>
    <dbReference type="OMA" id="IPTDAYR"/>
    <dbReference type="OrthoDB" id="373038at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019007">
        <property type="entry name" value="Wbp11/ELF5/Saf1_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09429">
        <property type="entry name" value="Wbp11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Wbp11/ELF5/Saf1 N-terminal" evidence="2">
        <location>
            <begin position="7"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="366"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="366"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="430"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="697" mass="82211" checksum="5EB4867FA9E5875F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXU0</accession>
    <name>A0A1J1GXU0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Syntaxin, Qa-SNARE family, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">SYN11</name>
        <name evidence="5" type="ORF">PGAL8A_00303600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528632.1">
        <property type="nucleotide sequence ID" value="XM_028672039.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXU0"/>
    <dbReference type="GeneID" id="39731569"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00303600"/>
    <dbReference type="OrthoDB" id="10255013at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="340"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="4">
        <location>
            <begin position="267"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="260"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="365" mass="43596" checksum="263921879B6FAEE4" modified="2017-02-15" version="1">MEDILNEIISLSEKKREEKEEKEKKKKKKNTSKDDDNYNFCDASTNCTVDDDLNIEKINIFSKIINDNKTNESDMFEDIEKNICENTPLFQNENTLNTYLLNVNDININISNIYKNIDKINVIKKKIDLNIYDNEKLYKKVNLIINDSEKIIEYIKIKINDLNKENNEFEKSSNMISEIKLRINIFIDVVNKYKGCINKYKNICNQYYEYVNKNIIKHYKLIHPNLSDHKIHKLIKQNNHSIEDFLNMNKTYQNSDIYSTNVEQIEIEKIKEKYNELKNLEKSILSLNELYIELAYVIKKRKNVINNIENNVFQVREYTEDALINIIEAKKYNAMIKQKILYFSIFLLIVAFIILFPIFFNFTLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY00</accession>
    <name>A0A1J1GY00_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial</fullName>
            <ecNumber evidence="15">1.3.5.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">SDHA</name>
        <name evidence="18" type="ORF">PGAL8A_00493900</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 15">
            <text>a quinone + succinate = fumarate + a quinol</text>
            <dbReference type="Rhea" id="RHEA:40523"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="13">Flavinylated by SdhE, about 5% flavinylation occurs in the absence of SdhE.</text>
    </comment>
    <comment type="pathway">
        <text evidence="15">Carbohydrate metabolism; tricarboxylic acid cycle; fumarate from succinate (eukaryal route): step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="15">Mitochondrion inner membrane</location>
            <topology evidence="15">Peripheral membrane protein</topology>
            <orientation evidence="15">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.1" evidence="15"/>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530162.1">
        <property type="nucleotide sequence ID" value="XM_028673739.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY00"/>
    <dbReference type="GeneID" id="39733472"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00493900"/>
    <dbReference type="OMA" id="NRCAETI"/>
    <dbReference type="OrthoDB" id="71672at2759"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER01006"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008177">
        <property type="term" value="F:succinate dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006121">
        <property type="term" value="P:mitochondrial electron transport, succinate to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.700.10:FF:000001">
        <property type="entry name" value="Mitochondrial succinate dehydrogenase flavoprotein subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.80.40:FF:000002">
        <property type="entry name" value="Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.100:FF:000001">
        <property type="entry name" value="Succinate dehydrogenase flavoprotein subunit (SdhA)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.100">
        <property type="entry name" value="Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.80.40">
        <property type="entry name" value="succinate dehydrogenase protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-dep_OxRdtase_2_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003952">
        <property type="entry name" value="FRD_SDH_FAD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037099">
        <property type="entry name" value="Fum_R/Succ_DH_flav-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015939">
        <property type="entry name" value="Fum_Rdtase/Succ_DH_flav-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030664">
        <property type="entry name" value="SdhA/FrdA/AprA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011281">
        <property type="entry name" value="Succ_DH_flav_su_fwd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014006">
        <property type="entry name" value="Succ_Dhase_FrdA_Gneg"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01816">
        <property type="entry name" value="sdhA_forward"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01812">
        <property type="entry name" value="sdhA_frdA_Gneg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11632">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11632:SF51">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN SUBUNIT, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02910">
        <property type="entry name" value="Succ_DH_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000171">
        <property type="entry name" value="SDHA_APRA_LASPO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46977">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00504">
        <property type="entry name" value="FRD_SDH_FAD_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 15" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6 13 15" id="KW-0274">FAD</keyword>
    <keyword evidence="5 13 15" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="3 15" id="KW-0813">Transport</keyword>
    <keyword evidence="4 15" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="FAD-dependent oxidoreductase 2 FAD-binding" evidence="16">
        <location>
            <begin position="35"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal" evidence="17">
        <location>
            <begin position="494"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="313"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="40"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="63"/>
            <end position="78"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="281"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="380"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="422"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="433"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="438"/>
            <end position="439"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="Tele-8alpha-FAD histidine" evidence="14">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000171-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR611281-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR611281-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR611281-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU362051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="CRG97360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="631" mass="70604" checksum="161680BC2E19C53E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY69</accession>
    <name>A0A1J1GY69_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">E3 ubiquitin-protein ligase CHFR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00316500</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CHFR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528760.1">
        <property type="nucleotide sequence ID" value="XM_028672181.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731698"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00316500"/>
    <dbReference type="OMA" id="QVNNGQV"/>
    <dbReference type="OrthoDB" id="6105938at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027370">
        <property type="entry name" value="Znf-RING_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23327">
        <property type="entry name" value="RING FINGER PROTEIN 127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13445">
        <property type="entry name" value="zf-RING_UBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="313"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="8">
        <location>
            <begin position="679"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="168"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="779"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="938"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1022"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="170"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="191"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="780"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="938"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1022"/>
            <end position="1035"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG95952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1336" mass="154843" checksum="F9B4E3D85454B78F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYD2</accession>
    <name>A0A1J1GYD2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">CCAAT-binding transcription factor, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00504200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530270.1">
        <property type="nucleotide sequence ID" value="XM_028673859.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYD2"/>
    <dbReference type="GeneID" id="39733575"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00504200"/>
    <dbReference type="OrthoDB" id="386949at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008623">
        <property type="term" value="C:CHRAC"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008622">
        <property type="term" value="C:epsilon DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031507">
        <property type="term" value="P:heterochromatin formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006272">
        <property type="term" value="P:leading strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22928">
        <property type="entry name" value="HFD_POLE3_DPB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051377">
        <property type="entry name" value="DNA_Pol-Epsilon_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46172">
        <property type="entry name" value="DNA POLYMERASE EPSILON SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46172:SF1">
        <property type="entry name" value="DNA POLYMERASE EPSILON SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription factor CBF/NF-Y/archaeal histone" evidence="4">
        <location>
            <begin position="36"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="111"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="149" mass="17396" checksum="E8301F9608CA9106" modified="2017-02-15" version="1">MENNNNIENINLIKETMFGLPNSVILKTIHNNIDLKNYRVKKEAIQTLSKCLSMFILYITDGALEHCENEKRSTIFIRDILNSLDDSLFLEIHDELKKQLTIQEEKDIIKNSKEGNNVEENNKNSEQNTQNNTREQNKDDFDILLQALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYK6</accession>
    <name>A0A1J1GYK6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Syntaxin, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00331400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528904.1">
        <property type="nucleotide sequence ID" value="XM_028672342.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYK6"/>
    <dbReference type="GeneID" id="39731844"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00331400"/>
    <dbReference type="OMA" id="ITRNRYF"/>
    <dbReference type="OrthoDB" id="75754at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006011">
        <property type="entry name" value="Syntaxin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14523">
        <property type="entry name" value="Syntaxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="323"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="3">
        <location>
            <begin position="251"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="247"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="345" mass="41037" checksum="248562FD01D57BE2" modified="2017-02-15" version="1">MSYSKKNDNKKLIEKNVYNYEFNSDIQKDIEVIQSYTLEISNISQNELCSIESSEKVQKIVQQGKIKIQEIQKKLKNCSNTEGFSQNEKVRKKLMLQKLSNSYMKAINNFQNASKNYINKTTLKYSYPNNFSTPDDLEGFNSFNNFSRNSSSNYDSNQDKFNVNIYDYNFYENKYENTYNSYKSNEFQSIDSRIEEKRKKKKYKNNIFTGNKKNEINEYLLQNDTYIENEKDNNYPQEKQFVSVKTVDIEKEILNQKNREIKKLHKDIINIQELYKELSEQINIQGENIDNIDSQIISTHDNIIMSGREIEIARNRYFRNFKCMFYIFIAILVLITIILVVLKVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYL3</accession>
    <name>A0A1J1GYL3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00513000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530358.1">
        <property type="nucleotide sequence ID" value="XM_028673957.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYL3"/>
    <dbReference type="GeneID" id="39733663"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00513000"/>
    <dbReference type="OMA" id="NSFQRHH"/>
    <dbReference type="OrthoDB" id="329083at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.560">
        <property type="entry name" value="Exo-inulinase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011977973" evidence="2">
        <location>
            <begin position="17"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="104"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="598" mass="70947" checksum="311D3B2647FEAD82" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYN0</accession>
    <name>A0A1J1GYN0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-editing substrate-binding complex 6 protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00492400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530147.1">
        <property type="nucleotide sequence ID" value="XM_028673723.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYN0"/>
    <dbReference type="GeneID" id="39733457"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00492400"/>
    <dbReference type="OrthoDB" id="432905at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058917">
        <property type="entry name" value="RESC6_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26188">
        <property type="entry name" value="RESC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA-editing substrate-binding complex 6 protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF26188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="504" mass="60178" checksum="B8B127A87A2C11F3" modified="2017-02-15" version="1">MNKYFNFLLRVKGSHNDIRSLFKNYFFFSTDRNINQIIIENNYSNIKNLKTQELRLLSENCCVKKINNVIIWSEISRNAIEKCNNFKYFDALLLLSSFDKMNILDKNLYKSFSDVFIKQINYLEPRHFILLINLYCKADIFPRVLFIQVFHSIIKYSSKLYPDEYVDLLICFANLKIVNKDLIKTLCKSIIKNINLFDYLHLCSIVGCLRSLDISDDVFYYVLDEKQLKELKFLTVQELYDNLKKIKLLTYSWEIYEKDLIKEFLLRINEFKNEKDVNQLDDPFTCLNYLISKNCVSNNFLIALSKWCANQVYEYPSRSAKRPLSFQLIKLYELMKEKKVENYDFIEKAIYRFVISRGGLENNRDKMVKPVSYQKGRKYIFTKDPLLNHNNSVDISKTRNNDININNNTNSNKNDMNENESFDDNINSFNKYIDNENYKGVNKNDSTYDNINNIKMTEKQKMINLSFEKKTEKKKNTYSYSRYCNFKLRQRPKRIKNKPVPAEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYQ8</accession>
    <name>A0A1J1GYQ8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00529100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530515.1">
        <property type="nucleotide sequence ID" value="XM_028674131.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYQ8"/>
    <dbReference type="GeneID" id="39733824"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00529100"/>
    <dbReference type="OrthoDB" id="371302at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="75" mass="9102" checksum="B2DB164668F43C72" modified="2017-02-15" version="1" fragment="single">MFKIHCIYLFIHFYFLVYIKCVFSYSYDKANLDNCSSIFCSYDKLSNIYKNSKFILTELENLLYDVRDEKTSHQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYT4</accession>
    <name>A0A1J1GYT4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00518900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530417.1">
        <property type="nucleotide sequence ID" value="XM_028674023.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYT4"/>
    <dbReference type="GeneID" id="39733722"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00518900"/>
    <dbReference type="OMA" id="YNTHEIS"/>
    <dbReference type="OrthoDB" id="385349at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="690"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="848"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="181"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="692"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="848"/>
            <end position="871"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1268" mass="149862" checksum="2BC1C4808FD35747" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ34</accession>
    <name>A0A1J1GZ34_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00514000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530368.1">
        <property type="nucleotide sequence ID" value="XM_028673968.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ34"/>
    <dbReference type="GeneID" id="39733673"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00514000"/>
    <dbReference type="OrthoDB" id="371247at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="155" mass="18362" checksum="875AD70BBEF15EE9" modified="2017-02-15" version="1">MKEKNTEKDFSNEEQISSSDDTDKENIISLRGFNISYKKKLEKLKTIDKIDNNKKIIKLILEDIQIDPKEIMQRVVNLLKEKAVLNGIIEINDQLYKIKYKEVIPDDNILFPEDINNIINCKHAYIGILKISKYTKKCTFNEKYLQKWQNESMDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ51</accession>
    <name>A0A1J1GZ51_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00030300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530667.1">
        <property type="nucleotide sequence ID" value="XM_028674300.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ51"/>
    <dbReference type="GeneID" id="39728826"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00030300"/>
    <dbReference type="OMA" id="KEDVCLA"/>
    <dbReference type="OrthoDB" id="1904536at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050576">
        <property type="entry name" value="Cilia_flagella_integrity"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45973:SF33">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_20, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45973">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52075">
        <property type="entry name" value="Outer arm dynein light chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="346" mass="40745" checksum="3D42CCE5961FD860" modified="2017-02-15" version="1">MEENNIILDDKKIMNYKIIKKICRENNLYETDELNNVLYLHMKGFHNIDGLSTFKNLKCLYINNNCIKKIQNLDGLTNLKALYLQNNDISTIENIECSSLIILNLSNNKIKTIKNLKHLKLLQTLNISNNLIENIIDLEEVSELQNLSHLDISGNNISFSSKYEISSISDCEKFIDSYVEKQSTSEIKKENTMKSIGNGNKEIDFFSFYKNFDEELNINENSDSIKYHQKIEEMDSVTKKKFSFLCEFIILIKKIKKLRTLFIKNNPFTNEIKYVSKYLIANIPRLVFLDDKKIKKEDICLAQIFLKKGLKEENELKKIFEKKKIEKYKNLREKFHTFLLKKSEKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ94</accession>
    <name>A0A1J1GZ94_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fam-b protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00032300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530685.1">
        <property type="nucleotide sequence ID" value="XM_028674320.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ94"/>
    <dbReference type="GeneID" id="39728846"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00032300"/>
    <dbReference type="OMA" id="LMYKEHS"/>
    <dbReference type="OrthoDB" id="376913at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013289308" description="Fam-b protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="119" mass="13807" checksum="92B25BF88D56B69C" modified="2017-02-15" version="1">MKIILFLTLIFVLLNCKSYGKSKIKKGKKGNSVTLGGDFLGDITPVPNSVYNLHVDLSKNYELNDFIIHNNEKINNALFLMYKEHYNTMKELQEIMNLRQELTDHLISEAKKLKNVFKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZF6</accession>
    <name>A0A1J1GZF6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD(+) kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00426100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529485.1">
        <property type="nucleotide sequence ID" value="XM_028672987.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZF6"/>
    <dbReference type="GeneID" id="39732793"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00426100"/>
    <dbReference type="OMA" id="GFKDDYI"/>
    <dbReference type="OrthoDB" id="185618at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019674">
        <property type="term" value="P:NAD+ metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.30">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017437">
        <property type="entry name" value="ATP-NAD_kinase_PpnK-typ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13158">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13158:SF5">
        <property type="entry name" value="NAD KINASE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="273"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="584" mass="68985" checksum="BF034930110C1FC8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZM8</accession>
    <name>A0A1J1GZM8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA repair protein RAD14, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RAD14</name>
        <name evidence="4" type="ORF">PGAL8A_00050500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530867.1">
        <property type="nucleotide sequence ID" value="XM_028674523.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZM8"/>
    <dbReference type="GeneID" id="39729030"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00050500"/>
    <dbReference type="OMA" id="YSKQMKL"/>
    <dbReference type="OrthoDB" id="68328at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000110">
        <property type="term" value="C:nucleotide-excision repair factor 1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901255">
        <property type="term" value="P:nucleotide-excision repair involved in interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000715">
        <property type="term" value="P:nucleotide-excision repair, DNA damage recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070914">
        <property type="term" value="P:UV-damage excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21075">
        <property type="entry name" value="DBD_XPA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.530.10">
        <property type="entry name" value="XPA C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000465">
        <property type="entry name" value="XPA/RAD14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037129">
        <property type="entry name" value="XPA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10142">
        <property type="entry name" value="DNA REPAIR PROTEIN COMPLEMENTING XP-A CELLS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10142:SF0">
        <property type="entry name" value="DNA REPAIR PROTEIN COMPLEMENTING XP-A CELLS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="Putative DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG98070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="350" mass="42214" checksum="055A5B4C15AE4E31" modified="2017-02-15" version="1">MIHTDESENEQEVNYNNILYDDNIGDGIEYYNDNLPHINFYLKFQKKHFLQNFFNEIEKEKGKKCIEKGKEEKICEDKESDDKIKEKDKNIKINELNVLNEGGFYIDDIPEECSDNSTENFYENPFISLSENIFHLDENEEQTKKINLIFQNHKNKFTFSIERILENDETSEQKCFLCYKKKKFNKILVNIKIYVCNECKSIDSNFRMISLSKLINKYCLNNYDLLKYEKQLALFSTKNPRGYLKQMKLYFLFQIKEIAIRKYGSLEKVKNLYNSKILNIRNKKVIKKNIHKLKKPKNIYSKEMMNMNKYKIICDNNEHDFDPPYCINQNDNIYKKNCKKCSYYVEYMQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZT5</accession>
    <name>A0A1J1GZT5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Proteasome subunit alpha type 5, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00052300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530885.1">
        <property type="nucleotide sequence ID" value="XM_028674543.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZT5"/>
    <dbReference type="GeneID" id="39729048"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00052300"/>
    <dbReference type="OMA" id="CLDIISY"/>
    <dbReference type="OrthoDB" id="1731724at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.410:FF:000005">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027040">
        <property type="entry name" value="PSMD4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10223">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10223:SF0">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13519">
        <property type="entry name" value="VWA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0647">Proteasome</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="5"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="384"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="385"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="410"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="426" mass="49298" checksum="EB9AD89E15E7A6E9" modified="2017-02-15" version="1">MSNIEATIICIDNSDYNRNEDIIPNRFLSQIDCINVLCCNKTSMHYKNNIGILMMAGDKIKVKVSLTNDIGQLLSCIHDIKLDGTCDIIRSLLIAQLALKHRVDKNLEQKIILFIGSPFDVNEKQLINTGKQLKKNNISVDIISFGNTNKNRDKLMKLFESVNNNDNCRFIECPENETNLSKFVLNSFLNHNDFNIDNMQDEQLISAMQMSLEENQNLNEKNNNNNDLPTIEEIENMKDIDNELKEALILSLKEYTEKNKSDNTNKEESDNNIHYNKKEENLTLVNESYKNNFDNNNENKLEDSKEKKENESYEKVFKLDKDENIVENSKYVINENIYNNDKNISKENDLTKTDEIDKNNASLIQDTNYISDILSKINNNSNVFDKNESKENSSNNKKTETNEQSNNEEDLVKNEENKDLSNNQNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H051</accession>
    <name>A0A1J1H051_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">6-cysteine protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00055600</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cell surface</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530918.1">
        <property type="nucleotide sequence ID" value="XM_028674580.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H051"/>
    <dbReference type="GeneID" id="39729081"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00055600"/>
    <dbReference type="OrthoDB" id="392647at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2860">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010884">
        <property type="entry name" value="6_CYS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038160">
        <property type="entry name" value="6_CYS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051444">
        <property type="entry name" value="Parasite_Repro/Invasion_Surf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38796">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38796:SF1">
        <property type="entry name" value="ANCHORED PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G09600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07422">
        <property type="entry name" value="s48_45"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00970">
        <property type="entry name" value="s48_45"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51701">
        <property type="entry name" value="6_CYS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012317362" evidence="10">
        <location>
            <begin position="21"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="11">
        <location>
            <begin position="21"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="11">
        <location>
            <begin position="221"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="125"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="125"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG98121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="358" mass="40940" checksum="A3A42F9E516CEAA8" modified="2017-02-15" version="1">MKVYLLYVLLLCLQQLSVYSLDHVCDFTKESNMRGTSNKKICEINAKPFDLITFKCPKKFGPKCFSSVSLSDDINNPNKLEAPMNQVLYGSIVYGDSVLISPVVPRNTTFYCFCNIESKISKETKNVVPKSEKKQEKEEEEEEEEEEVIEEPEEINEDAQRALDRVKKGRSVKYSEKTKPKESVVQEELIEEEEAQEQTQGKSRISKIGIMKVVVSSSPNKIKGCDFGSTFSDYFTKPFPLEKHGGSRVCKIEANPGEFVGFKCIYDSEGSIEPKNCFEKVYHNNTEKNLKDIMPGYISYNNGQNAHYAFYIRLPHFIQSSYTIQCKCRSTQSEFDNYIFELDVTGGESDIIENSFKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H059</accession>
    <name>A0A1J1H059_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Eukaryotic translation initiation factor 3 subunit I</fullName>
            <shortName evidence="7">eIF3i</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00063900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the WD repeat STRAP family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the eIF-3 subunit I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530997.1">
        <property type="nucleotide sequence ID" value="XM_028674668.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H059"/>
    <dbReference type="GeneID" id="39729164"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00063900"/>
    <dbReference type="OMA" id="VWFSHNG"/>
    <dbReference type="OrthoDB" id="24966at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071541">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex, eIF3m"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03008">
        <property type="entry name" value="eIF3i"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027525">
        <property type="entry name" value="eIF3i"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19877">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19877:SF1">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24805">
        <property type="entry name" value="EIF3I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 9" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="6"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="284"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG98200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="327" mass="37308" checksum="4B446FAADE497319" modified="2017-02-15" version="1">MKRKYLCGHNRPLTHVNTNYDGDLLFTTGRDKKFILWRVSDGTQIGLYECSGAVYNSDVTYDSKRIVCSSAANKVFLFDVYTGETLKIIEESGPVRFVEFNRNPLDQNKIIVAHDRLKADHKRFIKLYDLKSDNLIWKQEHESRCIQVRWCLFDKIILSAHENGEIIIWNAEDGHQIRKFQAHSKEVTNLAFDKNRMIMLSSSIDGTAILRDAVNFEIINEYKTDRPLNTCDISPLFKSENNPKNHIILAGGQAAEHVTTTASGEGKFQTLLYDIIHANELGSIKGHFGPVHSIKFLPHGDGFVSGGEDGFARIYHFDNDYFIGKYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0B1</accession>
    <name>A0A1J1H0B1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00062400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530982.1">
        <property type="nucleotide sequence ID" value="XM_028674651.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729149"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00062400"/>
    <dbReference type="OMA" id="KNIYFYH"/>
    <dbReference type="OrthoDB" id="377691at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1176"/>
            <end position="1195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1266"/>
            <end position="1286"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="9"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1375"/>
            <end position="1402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1743" mass="209387" checksum="D9E5E8FB3B025DAC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0M3</accession>
    <name>A0A1J1H0M3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fam-j protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00042600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG97997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530794.1">
        <property type="nucleotide sequence ID" value="XM_028674442.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0M3"/>
    <dbReference type="GeneID" id="39728951"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00042600"/>
    <dbReference type="OMA" id="TRIETHK"/>
    <dbReference type="OrthoDB" id="10580834at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="773" mass="90308" checksum="775B674CFFB11731" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0P7</accession>
    <name>A0A1J1H0P7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00045200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530818.1">
        <property type="nucleotide sequence ID" value="XM_028674469.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0P7"/>
    <dbReference type="GeneID" id="39728977"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00045200"/>
    <dbReference type="OMA" id="DKYQKNN"/>
    <dbReference type="OrthoDB" id="392474at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG98021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="756" mass="89720" checksum="B078A8429D7D7084" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H164</accession>
    <name>A0A1J1H164_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Amine oxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00063600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530994.1">
        <property type="nucleotide sequence ID" value="XM_028674664.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H164"/>
    <dbReference type="GeneID" id="39729161"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00063600"/>
    <dbReference type="OrthoDB" id="370517at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG98197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="451" mass="53921" checksum="E4A8C1E1A5163A6D" modified="2017-02-15" version="1">MRMGKTICLIGNGIDSLCLAYFMQRIKLRTHILLIKKKCNYINTYFHDSNIIENGCYSFILSENSKLFPSLLMNLNIETKILERNKYSNNISYLDENGNIYKINKFLFRIFYYFFKDYFFNKTINIEKSENLHSFSLKYFDKEICENLIFPYCYHYFNYSPQYVLMNSYFPNLMKEIKDKKSLIKSLLSCNKNNSIIFSKNKKIFTFKDGNEILTKKLIENLELSDDIKLTNNINNLQIKSKKNKVKIFLGRKVLKCKKVVFCLNPLELKNFLKKSKLENKKKNIIIKYLSNFRTTKIKITNVCFKKNVLPFSYSLESLLLIKKNEKNKLISLLYDNNIFPQFNKNISEKKNSEEDIFETSLRFLSKEQNDNKSINEINDFLQNILKVKEKPDLVISNNYDVFSYNEKFDKIFKKLINKHFRNVKIFWAFSFFKNFEFCLSEAKSFFETNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2I8</accession>
    <name>A0A1J1H2I8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Protein kinase, putative</fullName>
            <ecNumber evidence="10">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00512300</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="10"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530351.1">
        <property type="nucleotide sequence ID" value="XM_028673949.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2I8"/>
    <dbReference type="GeneID" id="39733656"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00512300"/>
    <dbReference type="OMA" id="GFMVQNI"/>
    <dbReference type="OrthoDB" id="272141at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:001316">
        <property type="entry name" value="Protein kinase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050591">
        <property type="entry name" value="GSK-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24057">
        <property type="entry name" value="GLYCOGEN SYNTHASE KINASE-3 ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24057:SF0">
        <property type="entry name" value="PROTEIN KINASE SHAGGY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="14"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG97550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="328" mass="38193" checksum="10D0924C96F9ECC9" modified="2017-02-15" version="1">MNKVKSIKKENPRYRLIKLIGKGTFGKVYSAVDLCTQEAVAIKRSPKWRNKVSREVDLLKKMNSSKNIVNIKSIFYTITKKGFRIQNIVFKYMTHSLGKYIRLKKQEKKENKSTRISPSDLKTIIYQICLGLKNLHKYNFAHRDLKPDNILIDLDSSTIQVEICDLGSAKKVHNNIISIPYICSRWYRAPELLCGSMYYTTEVDLWSLGCIIFELINFCPLFPGKFKKDQFSEECSQIINIIEVLGSPKMSFYENIKDYTSKKNNLLIKELCELNILPLSWNNILKHSLEENEKELINIIDGLLKWAPSERLKIEEVLSNPYFFSLND</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3A7</accession>
    <name>A0A1J1H3A7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)</fullName>
            <ecNumber evidence="3">1.2.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Branched-chain alpha-keto acid dehydrogenase E1 component beta chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">BCKDHB</name>
        <name evidence="10" type="ORF">PGAL8A_00025800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>N(6)-[(R)-lipoyl]-L-lysyl-[protein] + 3-methyl-2-oxobutanoate + H(+) = N(6)-[(R)-S(8)-2-methylpropanoyldihydrolipoyl]-L-lysyl-[protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:13457"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10497"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83142"/>
            <dbReference type="EC" id="1.2.4.4"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:13458"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.4" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530623.1">
        <property type="nucleotide sequence ID" value="XM_028674251.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3A7"/>
    <dbReference type="GeneID" id="39728781"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00025800"/>
    <dbReference type="OMA" id="SEAYYMA"/>
    <dbReference type="OrthoDB" id="878at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003863">
        <property type="term" value="F:branched-chain 2-oxo acid dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009083">
        <property type="term" value="P:branched-chain amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007584">
        <property type="term" value="P:response to nutrient"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07036">
        <property type="entry name" value="TPP_PYR_E1-PDHc-beta_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.920:FF:000004">
        <property type="entry name" value="2-oxoisovalerate dehydrogenase subunit beta 1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000001">
        <property type="entry name" value="Pyruvate dehydrogenase E1 beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42980:SF1">
        <property type="entry name" value="2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42980">
        <property type="entry name" value="2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="9">
        <location>
            <begin position="50"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00051764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00082400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG97823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="371" mass="41854" checksum="C8E2719C6A01F389" modified="2017-02-15" version="1">MKQLSNVTNLLKNSLKKNVNIVTKYDMYRNRKIQDGLRNFSTQNMEKKKMNMFTAINSAMHNVFEKDPNSILLGEDVAFGGVFRCSLDLLNKYGDKRVFNTPLCEQGIIGFAIGLAENGFTTIAEIQFGDYIFPAFDQIVNDVAKYRYRSGSSFDVGKLTIRSTWGAVGHGGLYHSQSPEAFFAHAAGIKIIVPSDAYKAKGLLLSAIKDPNPCLFFEPKNLYRSSVCEVPIDEYELELGKADVVKEGKDVTIVTWGSLVHKMKIAADILAKKHNIDCEIIDLQTIIPWDIDTVQKSVEKTGRLLISHEAQVTNGFGAEIAAKIQERCFYNLHTPIKRVCGYDTPFPHVYEPFYLPDEHKIVYEVKNMMKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3P6</accession>
    <name>A0A1J1H3P6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00054600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530908.1">
        <property type="nucleotide sequence ID" value="XM_028674569.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3P6"/>
    <dbReference type="GeneID" id="39729071"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00054600"/>
    <dbReference type="OrthoDB" id="375781at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG98111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="81" mass="9317" checksum="5039E7B612569AAE" modified="2017-02-15" version="1" fragment="single">KKKKKKKDKEKETSYISDTVTLCGTLIRDSMIAASEIIQNNYYPIKESIINAYDSYFCEYSQQSSSVNGNVPFFTIKPDNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3U3</accession>
    <name>A0A1J1H3U3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PPM-type phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00044900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530815.1">
        <property type="nucleotide sequence ID" value="XM_028674465.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728974"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00044900"/>
    <dbReference type="OMA" id="FNNYRFR"/>
    <dbReference type="OrthoDB" id="10266364at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039123">
        <property type="entry name" value="PPTC7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320:SF1">
        <property type="entry name" value="PROTEIN PHOSPHATASE PTC7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="2">
        <location>
            <begin position="148"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="528"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="822"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="987"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1262"/>
            <end position="1281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="528"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="828"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="997"/>
            <end position="1008"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1341" mass="158184" checksum="2B5F62205DE66AE0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2012-05-16" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>H7CDX1</accession>
    <name>H7CDX1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Apicoplast ribosomal protein S19, putative</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="4">Small subunit ribosomal protein 19</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rps19</name>
        <name evidence="5" type="synonym">RPS19</name>
        <name evidence="5" type="ORF">PGAL8A_API01500</name>
    </gene>
    <organism evidence="4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <geneLocation type="apicoplast" evidence="4"/>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2012" name="Mol. Biol. Evol." volume="29" first="2095" last="2099">
            <title>The Plasmodium Apicoplast Genome: Conserved Structure and Close Relationship of P. ovale to Rodent Malaria Parasites.</title>
            <authorList>
                <person name="Arisue N."/>
                <person name="Hashimoto T."/>
                <person name="Mitsui H."/>
                <person name="Palacpac N.M.Q."/>
                <person name="Kaneko A."/>
                <person name="Kawai S."/>
                <person name="Hasegawa M."/>
                <person name="Tanabe K."/>
                <person name="Horii T."/>
            </authorList>
            <dbReference type="PubMed" id="22396524"/>
            <dbReference type="DOI" id="10.1093/molbev/mss082"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">A8</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <dbReference type="EMBL" id="AB649424">
        <property type="protein sequence ID" value="BAL70741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LN835293">
        <property type="protein sequence ID" value="CRG98230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009325457.1">
        <property type="nucleotide sequence ID" value="NC_031963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="H7CDX1"/>
    <dbReference type="GeneID" id="30315797"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_API01500"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Apicoplast API"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="entry name" value="30s Ribosomal Protein S19, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_uS19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_uS19_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="Ribosomal protein S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0933">Apicoplast</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAL70741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG98230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="89" mass="10994" checksum="66204FF1368AF3A8" modified="2012-05-16" version="1">MIKLYWLKISLNNKYIFKNLNKNNNKNIILKIYNKNIYIYKKLLNIYLKVYNGCKFIPIYINKYKLYKKIGNFIYTKFIKNNIKELILD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKW9</accession>
    <name>A0A1J1GKW9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00073400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525852.1">
        <property type="nucleotide sequence ID" value="XM_028674956.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKW9"/>
    <dbReference type="GeneID" id="39729259"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00073400"/>
    <dbReference type="OrthoDB" id="372679at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012181803" description="Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2" evidence="2">
        <location>
            <begin position="22"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="249"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="283"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="308"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="338" mass="41314" checksum="21D6531E73B68195" modified="2017-02-15" version="1">MKILSLVFFFFLTYNYRKVLSYENNFVNNSNFLVLNKIKITSSYFTRNKREEKDLLTKTIDGNENENSYILINEKINSYNLININCTFKIKKEFDKTKLTIFLIKKLMDNHKENKNSYDIKELKTNETFIFTNEFKNHLVISNLSILVVNLIAFNGYYNFDILITDGKYSLKIPFFRVFLFFYNNLPITAYPIKKENMIIMSFMKKHLTRNYKKKYVNNVVYNYRDYYSLPLIQENNNFEKHEQMNTKIIIFIIFLMAYLFIVYIYLIFIYLKYNIKNVHTNYYNYVFIFSFMLIMFLFILYDFFLNIIQISYIFIFSFTFFLVVFYKTLTNLREIRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL68</accession>
    <name>A0A1J1GL68_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Chaperone protein ClpB1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00085600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525974.1">
        <property type="nucleotide sequence ID" value="XM_028671065.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL68"/>
    <dbReference type="GeneID" id="39729380"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00085600"/>
    <dbReference type="OMA" id="IDLHYTK"/>
    <dbReference type="OrthoDB" id="47330at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19499">
        <property type="entry name" value="RecA-like_ClpB_Hsp104-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000017">
        <property type="entry name" value="ATP-dependent chaperone ClpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000025">
        <property type="entry name" value="ATP-dependent Clp protease subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000010">
        <property type="entry name" value="Chaperone clpB 1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="entry name" value="Clp, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050130">
        <property type="entry name" value="ClpA_ClpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638:SF18">
        <property type="entry name" value="HEAT SHOCK PROTEIN 104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="Double Clp-N motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Clp R" evidence="7">
        <location>
            <begin position="135"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="602"/>
            <end position="660"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1031" mass="118077" checksum="9BEF89E3198DF403" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLA6</accession>
    <name>A0A1J1GLA6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00089400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526012.1">
        <property type="nucleotide sequence ID" value="XM_028671488.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLA6"/>
    <dbReference type="GeneID" id="39729418"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00089400"/>
    <dbReference type="OMA" id="LETFRCM"/>
    <dbReference type="OrthoDB" id="346839at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051229">
        <property type="entry name" value="ALYREF_mRNA_export"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19965">
        <property type="entry name" value="RNA AND EXPORT FACTOR BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19965:SF35">
        <property type="entry name" value="RNA ANNEALING PROTEIN YRA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101447">
        <property type="entry name" value="Formin homology 2 domain (FH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="396"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="20"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="38"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="471" mass="53818" checksum="7AE4E973892CB7DE" modified="2017-02-15" version="1">MEMPKETSAKLDMSLDEIVNKEALNNEKNGDKNDKKSVNLKKNRKKISLRKSKKKILNLSKNNQKNNNKILQKFPMNNANTSIVCPPPPPPPPPPPPMSKENSMNWNYRKSHNVNPNPTHLIANNTNHNLNLSHISSNPSHLNHVSTNPIGHNPNINIKTTNVNLSCISNCNMHMSTNVQSNLYYSNNSKKNYKINNIGDSANFITSPTLRPAPYQQNNNSININVEKKNSFVTNNFVHQNNNEYSYSDIHQQQNNNKKLSFSSNIRPNYSNLPIHNNSKFYLLKPPCDIVISKPPQNHLRPNEFNENKIIFANYQNNINENNTPKYFQPRNFVNESNTNFWGNNMNVPLPNNLQDSNTVNMKYPIFDQNIDKIKYNKYKEKITRMNNSVYAKKPHNIIVTNIPKNLTSREILETFRCMGNVLRADIMLTSKGEHSGCACITFADLESAALAASRYDGGTLNKQKIKVFVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLH8</accession>
    <name>A0A1J1GLH8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Repressor of RNA polymerase III transcription MAF1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00090000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526018.1">
        <property type="nucleotide sequence ID" value="XM_028671555.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLH8"/>
    <dbReference type="GeneID" id="39729424"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00090000"/>
    <dbReference type="OMA" id="FYVIENI"/>
    <dbReference type="OrthoDB" id="277029at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000994">
        <property type="term" value="F:RNA polymerase III core binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016480">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1000.50">
        <property type="entry name" value="Repressor of RNA polymerase III transcription Maf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015257">
        <property type="entry name" value="Maf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038564">
        <property type="entry name" value="Maf1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22504">
        <property type="entry name" value="REPRESSOR OF RNA POLYMERASE III TRANSCRIPTION MAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22504:SF0">
        <property type="entry name" value="REPRESSOR OF RNA POLYMERASE III TRANSCRIPTION MAF1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09174">
        <property type="entry name" value="Maf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="218" mass="26293" checksum="7D863F13C13520B6" modified="2017-02-15" version="1">MINLDIENLNDVNLILERLDAHDRFIEAKIELFEEIDKIKNNNSTNKKNICKKKIPEIINKKEKKSILSNIINILNYVFPDYEFKYLNNSNYKYIKNINSVIDNINYNLFYIIENIYRGFNKKIWKILKELIDFKYCDVYTYLNDTDNDPYVDKESISSFNYFFFAKKNKRILFISCITKPKYKNQNDEDFNNIYIGIQDEPSMNEQNEYDDENSSIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLZ3</accession>
    <name>A0A1J1GLZ3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">TatD-like deoxyribonuclease, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00107700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526194.1">
        <property type="nucleotide sequence ID" value="XM_028673510.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLZ3"/>
    <dbReference type="GeneID" id="39729603"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00107700"/>
    <dbReference type="OMA" id="CSDIFFE"/>
    <dbReference type="OrthoDB" id="6079689at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008296">
        <property type="term" value="F:3'-5'-DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01310">
        <property type="entry name" value="TatD_DNAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018228">
        <property type="entry name" value="DNase_TatD-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050891">
        <property type="entry name" value="TatD-type_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10060:SF15">
        <property type="entry name" value="DEOXYRIBONUCLEASE TATDN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10060">
        <property type="entry name" value="TATD FAMILY DEOXYRIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01091">
        <property type="entry name" value="TATD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="454" mass="54077" checksum="5F44B1093F226371" modified="2017-02-15" version="1">MQSIIYFIKYVIFLLYIYNIILKAKSFKVSKNIRYFIFFEKNIVFKRETKINLKKSTNIKKMDSQENLFIDIGANLTDKMFDGIYNKKKHENDLKYVLNRAKNNNVEKIIITCTCFEDIDKSLKICETYDPECNFLFLTAGVHPTSCFEFTGKKHIEETEMLAKKEFEDFIKYYENEKNFVEKKKCEDLVENKESNVNLSTTIINERKINSDEIRKEDFKIPGFVYDEKDQNYLEKLKEKIKNNSNRIVSIGEIGLDFDRLFFCPKYTQIKYFIYQLKLVEIFRLPIFLHMRNCSDIFFEILEKYKPLIEDVGAVIHSFTDQKETIERICNYKNLYIGVNGCSLKTFENINAVKKIPLNLLLLETDAPWCSLKKTHASYQFIKEKYEKRSYTNLKKIKNVIQCDDTTIFKERNEPYNIVDIAEITYKIKDPNITFDAFCKKIRCNTLNLFKKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM25</accession>
    <name>A0A1J1GM25_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Clp1-related protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00114700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526263.1">
        <property type="nucleotide sequence ID" value="XM_028674276.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM25"/>
    <dbReference type="GeneID" id="39729672"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00114700"/>
    <dbReference type="OMA" id="CILGVSY"/>
    <dbReference type="OrthoDB" id="258143at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051731">
        <property type="term" value="F:polynucleotide 5'-hydroxyl-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006388">
        <property type="term" value="P:tRNA splicing, via endonucleolytic cleavage and ligation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1030">
        <property type="entry name" value="Clp1, DNA binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045116">
        <property type="entry name" value="Clp1/Grc3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032324">
        <property type="entry name" value="Clp1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038239">
        <property type="entry name" value="Clp1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032319">
        <property type="entry name" value="CLP1_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12755">
        <property type="entry name" value="CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12755:SF6">
        <property type="entry name" value="POLYRIBONUCLEOTIDE 5'-HYDROXYL-KINASE CLP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16573">
        <property type="entry name" value="CLP1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16575">
        <property type="entry name" value="CLP1_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Clp1 N-terminal" evidence="4">
        <location>
            <begin position="55"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Clp1 P-loop" evidence="5">
        <location>
            <begin position="135"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="320"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="328"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="535" mass="61898" checksum="8BD1C233AD069FF3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM42</accession>
    <name>A0A1J1GM42_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">GTPase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00110000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526217.1">
        <property type="nucleotide sequence ID" value="XM_028673766.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM42"/>
    <dbReference type="GeneID" id="39729626"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00110000"/>
    <dbReference type="OMA" id="IYCHGNP"/>
    <dbReference type="OrthoDB" id="188276at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14858">
        <property type="entry name" value="TrmE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="entry name" value="Probable tRNA modification gtpase trme, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.430">
        <property type="entry name" value="tRNA modification GTPase MnmE domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00379">
        <property type="entry name" value="GTPase_MnmE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018948">
        <property type="entry name" value="GTP-bd_TrmE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004520">
        <property type="entry name" value="GTPase_MnmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027368">
        <property type="entry name" value="MnmE_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025867">
        <property type="entry name" value="MnmE_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42714">
        <property type="entry name" value="TRNA MODIFICATION GTPASE GTPBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42714:SF2">
        <property type="entry name" value="TRNA MODIFICATION GTPASE GTPBP3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12631">
        <property type="entry name" value="MnmE_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10396">
        <property type="entry name" value="TrmE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103025">
        <property type="entry name" value="Folate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116878">
        <property type="entry name" value="TrmE connector domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GTP-binding protein TrmE N-terminal" evidence="4">
        <location>
            <begin position="115"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="MnmE helical" evidence="5">
        <location>
            <begin position="316"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="domain" description="G" evidence="3">
        <location>
            <begin position="414"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="708" mass="84366" checksum="563E1EBA29D23456" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM85</accession>
    <name>A0A1J1GM85_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Rhomboid-like protease</fullName>
            <ecNumber evidence="10">3.4.21.105</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00121200</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Serine protease involved in intramembrane proteolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that are contributed by different transmembrane domains.</text>
            <dbReference type="EC" id="3.4.21.105"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Membrane</location>
            <topology evidence="2 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the peptidase S54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.105" evidence="10"/>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526327.1">
        <property type="nucleotide sequence ID" value="XM_028674725.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM85"/>
    <dbReference type="GeneID" id="39729737"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00121200"/>
    <dbReference type="OMA" id="HANWWHL"/>
    <dbReference type="OrthoDB" id="418595at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002610">
        <property type="entry name" value="Peptidase_S54_rhomboid-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22936:SF69">
        <property type="entry name" value="RHOMBOID-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22936">
        <property type="entry name" value="RHOMBOID-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10 12" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="128"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="184"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="207"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S54 rhomboid" evidence="11">
        <location>
            <begin position="87"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG93505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="267" mass="30683" checksum="E491EC2AF9B4F9F5" modified="2017-02-15" version="1">MLRKDTQNEENLDFLSENIELIGKNIKSKYYNVLFPDISLNKIIVWISFFQIIIYILSCLLSENLEAPNVQVLMFLGATYGPSIKQGELWRLLFPIFLHANWWHLIINILCILNLGLIIESKYKRSRFLLIYFLSGIIGNVLTTICNPCQLAVGASTSGFGLIGCSILEIFLAWENLTKKAKNYYIFNISIFLIFFLFVSFSPSVDFFGHIGGFLCGAFLACHYNKFIGYNFFQESLYYSFAAICTLIILYLPIRLFVNNMSCELGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GME9</accession>
    <name>A0A1J1GME9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">leucine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Leucyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PGAL8A_00121400</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>tRNA(Leu) + L-leucine + ATP = L-leucyl-tRNA(Leu) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:11688"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.4" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526329.1">
        <property type="nucleotide sequence ID" value="XM_028674727.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729739"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00121400"/>
    <dbReference type="OrthoDB" id="15954at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004823">
        <property type="term" value="F:leucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006429">
        <property type="term" value="P:leucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002302">
        <property type="entry name" value="Leu-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43740:SF2">
        <property type="entry name" value="LEUCINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43740">
        <property type="entry name" value="LEUCYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00985">
        <property type="entry name" value="TRNASYNTHLEU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="337"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="12">
        <location>
            <begin position="110"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="12">
        <location>
            <begin position="590"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="12">
        <location>
            <begin position="966"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="13">
        <location>
            <begin position="1172"/>
            <end position="1297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG93507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1336" mass="160751" checksum="D946C124057DF423" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMQ7</accession>
    <name>A0A1J1GMQ7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Myosin motor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00141600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526532.1">
        <property type="nucleotide sequence ID" value="XM_028674952.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMQ7"/>
    <dbReference type="GeneID" id="39729940"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00141600"/>
    <dbReference type="OMA" id="MELDEYA"/>
    <dbReference type="OrthoDB" id="6108017at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000146">
        <property type="term" value="F:microfilament motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.4820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140">
        <property type="entry name" value="MYOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140:SF270">
        <property type="entry name" value="MYOSIN-12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00193">
        <property type="entry name" value="MYOSINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0505">Motor protein</keyword>
    <keyword evidence="3 6" id="KW-0518">Myosin</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myosin motor" evidence="7">
        <location>
            <begin position="91"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="region of interest" description="Actin-binding" evidence="6">
        <location>
            <begin position="730"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="186"/>
            <end position="193"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="922" mass="109072" checksum="0CD8482BC6E02275" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN23</accession>
    <name>A0A1J1GN23_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">acetate--CoA ligase</fullName>
            <ecNumber evidence="2">6.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00156300</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.1" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526676.1">
        <property type="nucleotide sequence ID" value="XM_028675113.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN23"/>
    <dbReference type="GeneID" id="39730088"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00156300"/>
    <dbReference type="OMA" id="INVSYNC"/>
    <dbReference type="OrthoDB" id="1706066at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003987">
        <property type="term" value="F:acetate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006085">
        <property type="term" value="P:acetyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05966">
        <property type="entry name" value="ACS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12780:FF:000045">
        <property type="entry name" value="Acetyl-CoA synthetase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032387">
        <property type="entry name" value="ACAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24095">
        <property type="entry name" value="ACETYL-COENZYME A SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24095:SF14">
        <property type="entry name" value="ACETYL-COENZYME A SYNTHETASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16177">
        <property type="entry name" value="ACAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acetyl-coenzyme A synthetase N-terminal" evidence="8">
        <location>
            <begin position="57"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="6">
        <location>
            <begin position="115"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="6">
        <location>
            <begin position="440"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="7">
        <location>
            <begin position="737"/>
            <end position="845"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="891" mass="100883" checksum="773819716FD0131C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN38</accession>
    <name>A0A1J1GN38_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GDT1 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00155850</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the GDT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526671.1">
        <property type="nucleotide sequence ID" value="XM_028675106.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN38"/>
    <dbReference type="GeneID" id="39730083"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00155850"/>
    <dbReference type="OMA" id="ILGHAIC"/>
    <dbReference type="OrthoDB" id="442680at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015085">
        <property type="term" value="F:calcium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032468">
        <property type="term" value="P:Golgi calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032472">
        <property type="term" value="P:Golgi calcium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001727">
        <property type="entry name" value="GDT1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12608:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 165"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12608">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN HTP-1 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01169">
        <property type="entry name" value="GDT1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="207" mass="24066" checksum="6DB66A067407FFA6" modified="2017-02-15" version="1">MKSYVSELALIFFSVTASEIFDKTFFIVILLGFTTKSWVQVFLGSYIGLISMTVIICLMGNHLSKYFSKFTFQVVSSVLFFLFSLQIFFNLFKEKKKSSCEEAEEEIKKLNFKHKLFTLYPIFFKTFILTVLSEFGDKSQIASFMLSSTYSFSIVIFASLFAYAFCIGLAILINFFGKCNINEFYIQMLSGFFFLFASFYTIYEIFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN53</accession>
    <name>A0A1J1GN53_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RAP protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00157400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526687.1">
        <property type="nucleotide sequence ID" value="XM_028675125.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN53"/>
    <dbReference type="GeneID" id="39730099"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00157400"/>
    <dbReference type="OMA" id="KNHYWYF"/>
    <dbReference type="OrthoDB" id="385235at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013584">
        <property type="entry name" value="RAP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08373">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00952">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51286">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RAP" evidence="1">
        <location>
            <begin position="1130"/>
            <end position="1193"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1197" mass="144071" checksum="C2C49DC266A9963D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNE3</accession>
    <name>A0A1J1GNE3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10 12">Adenylosuccinate synthetase</fullName>
            <shortName evidence="10">AMPSase</shortName>
            <shortName evidence="10">AdSS</shortName>
            <ecNumber evidence="10 12">6.3.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">IMP--aspartate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ADSS</name>
        <name evidence="13" type="ORF">PGAL8A_00160900</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Plays an important role in the de novo pathway of purine nucleotide biosynthesis.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Plays an important role in the salvage pathway for purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.</text>
    </comment>
    <comment type="function">
        <text evidence="9">Plays an important role in the salvage pathway for purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 12">
            <text>IMP + L-aspartate + GTP = N(6)-(1,2-dicarboxyethyl)-AMP + GDP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:15753"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="6.3.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10 12">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1 10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="10">Parasitic protozoa lack the de novo purine biosynthesis pathway and rely exclusively on the salvage pathway for their purine nucleotide requirements.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10 12">Belongs to the adenylosuccinate synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.4" evidence="10 12"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526722.1">
        <property type="nucleotide sequence ID" value="XM_028675163.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNE3"/>
    <dbReference type="GeneID" id="39730134"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00160900"/>
    <dbReference type="OMA" id="FHHAKPI"/>
    <dbReference type="OrthoDB" id="10265645at2759"/>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004019">
        <property type="term" value="F:adenylosuccinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046040">
        <property type="term" value="P:IMP metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03108">
        <property type="entry name" value="AdSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.170.10:FF:000001">
        <property type="entry name" value="Adenylosuccinate synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.440.10">
        <property type="entry name" value="Adenylosuccinate Synthetase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.300.10">
        <property type="entry name" value="Adenylosuccinate Synthetase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.170.10">
        <property type="entry name" value="Adenylosuccinate Synthetase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00011">
        <property type="entry name" value="Adenylosucc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018220">
        <property type="entry name" value="Adenylosuccin_syn_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033128">
        <property type="entry name" value="Adenylosuccin_syn_Lys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042109">
        <property type="entry name" value="Adenylosuccinate_synth_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042110">
        <property type="entry name" value="Adenylosuccinate_synth_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042111">
        <property type="entry name" value="Adenylosuccinate_synth_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001114">
        <property type="entry name" value="Adenylosuccinate_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002223">
        <property type="entry name" value="PRK01117.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00184">
        <property type="entry name" value="purA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11846">
        <property type="entry name" value="ADENYLOSUCCINATE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11846:SF0">
        <property type="entry name" value="ADENYLOSUCCINATE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00709">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00788">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01266">
        <property type="entry name" value="ADENYLOSUCCIN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00513">
        <property type="entry name" value="ADENYLOSUCCIN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 10 12" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 10 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 10 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 10 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 10 12" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="26"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="25"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="26"/>
            <end position="29"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="51"/>
            <end position="54"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="53"/>
            <end position="55"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="307"/>
            <end position="313"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="339"/>
            <end position="341"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="425"/>
            <end position="427"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG93901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="442" mass="50114" checksum="37C2EEFED4461CD3" modified="2017-02-15" version="1">MDIFNHDIKNVDKGNVVAVLGAQWGDEGKGKIIDILSKYSDITCRFNGGSNAGHTISVNNKKYALHLLPCGVLYENNINVLGNGMVVHIKSLIEEINSIGGNILDRLYLSNKLHILFDIHQIIDSLQENEKLKEGSQLGTTKRGIGPCYSTKASRIGVRLGTLKNFENFKKIYIKLIDHLMGLYNITQYDKEEELNLFYKYHLILKDKIVDVVSFMNKSIENNKKILIEGANAAMLDIDFGTYPYVTSSSTTVGGIFSGLGINYKKLNLVIGVVKSYLTRVGCGPFLTELDNEIGEYLREKGYEYGTTTKRPRRCGWLDIPMLLYVKHINSIDIINLTKLDVLSGLKEILLCTNFVNKKTGKLLEKDCYPIDEDELAEYDPVYEKFEGWEEDISCCKEFEDLPLNARKYIFAIEKYLKIPIVWIGVGPNRENMITKKIFSIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNG0</accession>
    <name>A0A1J1GNG0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ferrochelatase, putative</fullName>
            <ecNumber evidence="9">4.99.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">FC</name>
        <name evidence="9" type="ORF">PGAL8A_00171400</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Porphyrin-containing compound metabolism; protoheme biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the ferrochelatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.99.1.1" evidence="9"/>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526828.1">
        <property type="nucleotide sequence ID" value="XM_028670036.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNG0"/>
    <dbReference type="GeneID" id="39730241"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00171400"/>
    <dbReference type="OMA" id="RFLSGYC"/>
    <dbReference type="OrthoDB" id="1323at2759"/>
    <dbReference type="UniPathway" id="UPA00252"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004325">
        <property type="term" value="F:ferrochelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006783">
        <property type="term" value="P:heme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00419">
        <property type="entry name" value="Ferrochelatase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03411">
        <property type="entry name" value="Ferrochelatase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1400:FF:000002">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1400">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00323">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001015">
        <property type="entry name" value="Ferrochelatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033644">
        <property type="entry name" value="Ferrochelatase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033659">
        <property type="entry name" value="Ferrochelatase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00109">
        <property type="entry name" value="hemH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11108">
        <property type="entry name" value="FERROCHELATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11108:SF1">
        <property type="entry name" value="FERROCHELATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00762">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53800">
        <property type="entry name" value="Chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="6 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="350" mass="40901" checksum="1C2F296CC85B1B1F" modified="2017-02-15" version="1">MDLNEFLKYNNLKISKDKIKNLDKNKIGILITNLGSPERPTYWALYKYLSQFLGDPRVVKLNRFFWLPILYGFILPFRSGNSASKYKKIWTKEGSPLCVNTYNQYMALKKLLFEKYNDKIIISYGMRYGEKSIKNGLDYLKKENINKLLIFPLYPQSAECTVASTLDSVSDSLKNWINIPELRFLSGYCFHERYINSLKENIENFWKVNGKGKKLIISYHGLPTKTVMEGDLYPFFCIESTNKLIHKLNLKKDNYVLAFQSRIEGQEWIQPNIEDIIIKLALEGYDKVDVICPSFSSDCLETLEEIKISYQELFQKHCKGELRYIKCLNDSKIGIDLLMNIIEENIVGWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNV7</accession>
    <name>A0A1J1GNV7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">50S ribosomal protein L22, mitochondrial, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00387100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526988.1">
        <property type="nucleotide sequence ID" value="XM_028670214.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNV7"/>
    <dbReference type="GeneID" id="39732401"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00387100"/>
    <dbReference type="OMA" id="RIREMPM"/>
    <dbReference type="OrthoDB" id="416470at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.10">
        <property type="entry name" value="Ribosomal protein L22/L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001063">
        <property type="entry name" value="Ribosomal_uL22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047867">
        <property type="entry name" value="Ribosomal_uL22_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036394">
        <property type="entry name" value="Ribosomal_uL22_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13501">
        <property type="entry name" value="CHLOROPLAST 50S RIBOSOMAL PROTEIN L22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13501:SF10">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL22M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00237">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54843">
        <property type="entry name" value="Ribosomal protein L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="288" mass="35720" checksum="715158D68E2C294F" modified="2017-02-15" version="1">MFNNLSKIIYSNLFLINKKYINTNVQLRNPYYRKKGFWEWRRRIIHRYNEKRYIKKNIKPKVKNKNEVSIKNKKEDVYWTFKVYQLKISLRNLYNFGRLIKGLHLEDAIVFLESIPQIRVNSILNSLLNSKEKIINNFNGDASRLYIDNVQIHYNTPMKYIKYHAMGHFGLVKSYRNTFTYTIKQMNIQEFYHKIFIRGNVPRTLSHNMRLYLNQNRINMNTLIEWYPYICANSRYYFREKLRYLNNMYQFNYYKSRHKWIQNYFNNIERRTNELRLQRNIITEKMKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPB6</accession>
    <name>A0A1J1GPB6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00396500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527082.1">
        <property type="nucleotide sequence ID" value="XM_028670318.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPB6"/>
    <dbReference type="GeneID" id="39732495"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00396500"/>
    <dbReference type="OMA" id="LMLREME"/>
    <dbReference type="OrthoDB" id="380041at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="131"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="403" mass="48644" checksum="DB8BBB9DF127FDA1" modified="2017-02-15" version="1">MIIENRKKDLEIRIYEEEIYEDLQKVYKEKYSKYVNEDNYEIFAYEANTDIIDYNIYYENYQNKNKKNNSEIILKNIDANESFKKFIGKKLNAQSEYYELTKNDKRKMEAIQKYIPFCKYNKGVLSRITQIKNTLSNIKNYINSKKKLENNKQLLTTDILLHLLEIDNKISAIIKYGEIYDLDFFNNVKYYKYINNSIRCKSLNIFEIIQKLKSIANNNQLDKKIKIVNFNNILSFQKKIFYDKFKEISYKIDNFQSLLYENCFNERENIANILLSFYLFISLCFNENMNKRILNYIYLVNLKIRKCKEYLENEKNIKILKMLSDFKSITNIYYDEKSFKETFFISLNQDNEILLQLYKKLLHNEISIGLILNETDKINNLIELLNQNLDKNNKMIKSLFNVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPD6</accession>
    <name>A0A1J1GPD6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Palmitoyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">DHHC11</name>
        <name evidence="9" type="ORF">PGAL8A_00406500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527182.1">
        <property type="nucleotide sequence ID" value="XM_028670429.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPD6"/>
    <dbReference type="GeneID" id="39732595"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00406500"/>
    <dbReference type="OMA" id="VCVVMTW"/>
    <dbReference type="OrthoDB" id="331948at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12246">
        <property type="entry name" value="PALMITOYLTRANSFERASE ZDHHC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="135"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="8">
        <location>
            <begin position="88"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="256" mass="30430" checksum="C403A462C6E3871D" modified="2017-02-15" version="1">MKPNIKETFYTLYKSFYVFLTYVLILQSIYLCSKFILTFTIKIKIFFLFSFWFSSFMTLWCYIKCLLKNPGTLSHSEITEENIIECNNKIEMCKKCNLLKIKRSHHCSACNKCIIKMDHHCMWINNCVGLYNQKYFILLNFYSLLMCLNCSFIIIYKIITCIKIQFNLKREICVISRMDIFLILLNAICSLIFGMLAFVMLVDQYCAIRTNTTGVEFLKKEKGEKKSFNELIIEVFGHSFSYLWFFPIDKNIKKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPN0</accession>
    <name>A0A1J1GPN0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">COX assembly mitochondrial protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00095300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the CMC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526069.1">
        <property type="nucleotide sequence ID" value="XM_028672121.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPN0"/>
    <dbReference type="GeneID" id="39729477"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00095300"/>
    <dbReference type="OrthoDB" id="6224010at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013892">
        <property type="entry name" value="Cyt_c_biogenesis_Cmc1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08583">
        <property type="entry name" value="Cmc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU364104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="163" mass="20076" checksum="FE94C291CDBD8B8B" modified="2017-02-15" version="1">MRKIWTPIRRSEDQKIIKNNYDEEEKENFEKSLPKDFIENNRKNRNPYFEIKESTLIEQKEKKEAQKILALELRDKCRAEIDEYVECSVGRLWTILKCKDLMVKMRKCLKKYENLEYVKFREKQILEERKKNGTSLLRSDERARYNRFVYTDKEKGWIPEKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPN4</accession>
    <name>A0A1J1GPN4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00396400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527081.1">
        <property type="nucleotide sequence ID" value="XM_028670317.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPN4"/>
    <dbReference type="GeneID" id="39732494"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00396400"/>
    <dbReference type="OMA" id="EVWAIRV"/>
    <dbReference type="OrthoDB" id="363220at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="279" mass="32431" checksum="126FC0D34EDDB97B" modified="2017-02-15" version="1">MVKIELVDAGCFISQMNELLLIDPLYITYAITHYFNCFINDKKDLLPQESLNGIYFPNAKAGLWSSFAIRENNNFSCNSKDTDRKKYDQDKSYNNEMVISLICFNNTEFMHEYMTIQKINELDWQTYEINKNHIGNSLNNKNNNLNNEKDYSDESFHLSNYFTNILTVESGQVGLFCIESIKRSSNILFEKNTNNDINNKEQLDNLFRENLNVLYPWYNKICDLTLSSSIGIIDLIDKPVGCVCISNSDCVVNYLCEIVKDDITDEIWAIRVNFLKPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPQ8</accession>
    <name>A0A1J1GPQ8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Stomatin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00398200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the band 7/mec-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527099.1">
        <property type="nucleotide sequence ID" value="XM_028670337.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPQ8"/>
    <dbReference type="GeneID" id="39732512"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00398200"/>
    <dbReference type="OMA" id="YLQMLPK"/>
    <dbReference type="OrthoDB" id="434619at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08829">
        <property type="entry name" value="SPFH_paraslipin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.479.30:FF:000004">
        <property type="entry name" value="Putative membrane protease family, stomatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050710">
        <property type="entry name" value="Band7/mec-2_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032435">
        <property type="entry name" value="STML2-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43327">
        <property type="entry name" value="STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43327:SF10">
        <property type="entry name" value="STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16200">
        <property type="entry name" value="Band_7_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="5">
        <location>
            <begin position="77"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="184"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG94278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="374" mass="42697" checksum="0604B931334E5C2E" modified="2017-02-15" version="1">MIILNRRIIWGKAFLQNYKCIKYNKNTLNQNRNYYTSNYILQNHKSTNCNRNVFNQSRNFYTSNGNKKFSKKFWNSLGFVIIPQETAYIVERLGKYKKTLLAGFHFLIPFIDKIAYVFSLKEETITIPNQTAITKDNVTLNIDGVLYIKCENPYNSSYGIEDAVFAVTQLAQVTMRSELGKLTLDATFLERDNLNEKIVKAINESAKNWGIKCMRYEIRDIILPLNIKNAMEKQAEAERRKRAEILQSEGERESEINIAIGKKRKSILIAEGQSFAIKAKADATAEAIEIISNKIKKLDSNNAISLLIAEQYIDVFSNICKNNNTIIIPADLNNISSLISQSLSIYNNIKNSKNTSNNIESLSNNNLIQSDVKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPU7</accession>
    <name>A0A1J1GPU7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00402200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527139.1">
        <property type="nucleotide sequence ID" value="XM_028670381.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPU7"/>
    <dbReference type="GeneID" id="39732552"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00402200"/>
    <dbReference type="OMA" id="LFLTWAN"/>
    <dbReference type="OrthoDB" id="346371at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042410">
        <property type="entry name" value="WBSCR13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44321">
        <property type="entry name" value="TRANSDUCIN BETA-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44321:SF1">
        <property type="entry name" value="TRANSDUCIN BETA-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="358"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="394" mass="45548" checksum="1D5B9F75DFD4D0E3" modified="2017-02-15" version="1">MLTIIFSVLVIVFIIWGSRLLNKKKKEANLKTDNITKNKVKETPRHKKTTLEVKKNIPLIKTVKNNIPHVLFDRNIAVLKGNNYPLSLCINEKYGIIAISCNNGNIQIHKIYKDNVNKSIINKKMGEVYSCIDIDEEGNHLVAVDELTSTLRIFNIEKSENNIKNFSLILKGKTELHKKDVKFLYVHKNSYIITGSELDETEVKIWNMKGEIIKIISIKQIYNHDYAISTSGRFFGVACWSPGVKVFEIKLKENVFQNIEKVMDLKTNSGTKCICFSNDEEKAFIIDKHGILTAYNLNIRYKLQEDSKILYKKDLKEYNFEDFSRMSMSGDSKYLILISGCNLLILKQENLEMVNKIMDSHQCEIYNVRPIPNSSLFLTWANDGYIKLWNISKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ50</accession>
    <name>A0A1J1GQ50_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00182000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527249.1">
        <property type="nucleotide sequence ID" value="XM_028670503.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730347"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00182000"/>
    <dbReference type="OMA" id="IPLLWIR"/>
    <dbReference type="OrthoDB" id="21449at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026320">
        <property type="entry name" value="PRR14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14522">
        <property type="entry name" value="EMO2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14522:SF2">
        <property type="entry name" value="PROLINE-RICH PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="63"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="356"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="824"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="882"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1511"/>
            <end position="1536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1768"/>
            <end position="1798"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1907"/>
            <end position="1934"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2663"/>
            <end position="2684"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1546"/>
            <end position="1585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="70"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="365"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="392"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="402"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="534"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1517"/>
            <end position="1526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1527"/>
            <end position="1536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1768"/>
            <end position="1787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1913"/>
            <end position="1934"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2667"/>
            <end position="2684"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3380" mass="407765" checksum="26A7B36ED13B6C77" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQA7</accession>
    <name>A0A1J1GQA7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Allantoicase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00199700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the allantoicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527415.1">
        <property type="nucleotide sequence ID" value="XM_028670687.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQA7"/>
    <dbReference type="GeneID" id="39730523"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00199700"/>
    <dbReference type="OMA" id="ENQNTPW"/>
    <dbReference type="OrthoDB" id="10266039at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004037">
        <property type="term" value="F:allantoicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000256">
        <property type="term" value="P:allantoin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005164">
        <property type="entry name" value="Allantoicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015908">
        <property type="entry name" value="Allantoicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12045">
        <property type="entry name" value="ALLANTOICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12045:SF3">
        <property type="entry name" value="INACTIVE ALLANTOICASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03561">
        <property type="entry name" value="Allantoicase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Allantoicase" evidence="3">
        <location>
            <begin position="94"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="Allantoicase" evidence="3">
        <location>
            <begin position="323"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="16"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="474" mass="55914" checksum="061C01D168241206" modified="2017-02-15" version="1">MNECKDINEEENKILCQTKETKISKKRKLYENEENNNNNEENRKQKKKKKFLNIFNGFFNWITSRSIKIPSKEIESINEVNFLNFNNVLSKHYGSKVLFVTDESIGKSDNLLVDDKMGWITRRRRDVGHEWLILKLKYPSIIYGIELNFENIDEDICPHLSIEVVENCSIDDVIKEEEFIISETEKDEKLVKKKSYNFLESYKIDKSISDLLESQDTPWIELLQADCVDFLKCFTKKKLYYFKINDQSLIKPWTHIRINLYPDGGINKINLYGEFVSLFKKHTIVSKQKIFLNKPENGCTLIYYHCDDIYKGHPKNMIDSYKTEGFCTNRLFNRPPIILRTLIYNSIKNISIFKFGVRGIIENFTIDIGNYKYDHPECIQIYLLDCIDILTLDLLEQKRIFEEDEKLQKKKIDWLQLPPCKLATDQQKTFYNFNLLEYNFTIMERTATHFKVSLHPDGGISQINVIGTVLSTPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQC8</accession>
    <name>A0A1J1GQC8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-f protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00186700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000025">
        <property type="protein sequence ID" value="CRG94472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527291.1">
        <property type="nucleotide sequence ID" value="XM_028670550.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQC8"/>
    <dbReference type="GeneID" id="39730394"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00186700"/>
    <dbReference type="OrthoDB" id="1490254at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="584" mass="70374" checksum="5386F9F13A9D01DC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQE2</accession>
    <name>A0A1J1GQE2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine hydroxymethyltransferase, putative</fullName>
            <ecNumber evidence="4">2.1.2.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SHMT</name>
        <name evidence="4" type="ORF">PGAL8A_00215400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.1" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527572.1">
        <property type="nucleotide sequence ID" value="XM_028670861.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQE2"/>
    <dbReference type="GeneID" id="39730681"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00215400"/>
    <dbReference type="OrthoDB" id="392000at2759"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004372">
        <property type="term" value="F:glycine hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019264">
        <property type="term" value="P:glycine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049943">
        <property type="entry name" value="Ser_HO-MeTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039429">
        <property type="entry name" value="SHMT-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680">
        <property type="entry name" value="SERINE HYDROXYMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680:SF35">
        <property type="entry name" value="SERINE HYDROXYMETHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00464">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Serine hydroxymethyltransferase-like" evidence="3">
        <location>
            <begin position="79"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="453" mass="53578" checksum="225A306AB8015622" modified="2017-02-15" version="1">MLRKKFNNIKYNLKRYISFDSLRNRSSLKDVDDGIFNMLSLYKNNNNINLSVINNIIPLYLKECLINDINKTIQCNKNVSEMIENRALNSFNLEKKYWGFLINSYSNCINSHNDYFLLKLYNSLINNRNKIMHISFSLEKKNNKNKRNCLLDTVYNTIKIENENNINYKQIKDIYEIFRPDIIYIDETNNPYNFEYEFIKNLKDINNSIVIVNISNKANLISQNLIPTPFEYSDIVFSFLNENFRAHNSYIVFYKKGFKYFNNEGKLISYDFEEKLKNIFSENNLNNIVFSLATSFKLMKNTEFKEYANQVQKNASILFKYINKEYFNIHYSGNNSFLNLNPSNYSFNVQEFYTLCTKLNIFFDVLSPTKCIQKSFNIGTSYLTSLGLLEKDMKIVADFINQSISLYFHMKQKENLSNEKFIEYINNSTTSEILSLANDVFCFISSFPCMKSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQK4</accession>
    <name>A0A1J1GQK4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00218800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527606.1">
        <property type="nucleotide sequence ID" value="XM_028670900.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQK4"/>
    <dbReference type="GeneID" id="39730715"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00218800"/>
    <dbReference type="OMA" id="HLYSYAF"/>
    <dbReference type="OrthoDB" id="377164at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="876" mass="105338" checksum="1FAB6BB83C3B47D0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQL5</accession>
    <name>A0A1J1GQL5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Replication factor C3, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">RFC3</name>
        <name evidence="8" type="ORF">PGAL8A_00222600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the activator 1 small subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527644.1">
        <property type="nucleotide sequence ID" value="XM_028670941.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQL5"/>
    <dbReference type="GeneID" id="39730753"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00222600"/>
    <dbReference type="OMA" id="AEDNLPW"/>
    <dbReference type="OrthoDB" id="4199794at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005663">
        <property type="term" value="C:DNA replication factor C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18140">
        <property type="entry name" value="HLD_clamp_RFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.272.10:FF:000004">
        <property type="entry name" value="Replication factor C subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000129">
        <property type="entry name" value="Replication factor C subunit 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050238">
        <property type="entry name" value="DNA_Rep/Repair_Clamp_Loader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013748">
        <property type="entry name" value="Rep_factorC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047854">
        <property type="entry name" value="RFC_lid"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001679">
        <property type="entry name" value="PRK00440.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669">
        <property type="entry name" value="REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669:SF9">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25361">
        <property type="entry name" value="AAA_lid_RFC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08542">
        <property type="entry name" value="Rep_fac_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="7">
        <location>
            <begin position="45"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="344" mass="39567" checksum="2F09825495FACD81" modified="2017-02-15" version="1">MTEVQHQKTEELTPWVEKYRPNVLSDIISHEQVISTIKKFVQKGELPHLLLHGPPGTGKTSTILAVCKELYGDSRSSFVLELNASDDRGINVIRDQIKTFAESKNHYNTCEKTTLKLIILDEADHMTFPAQNAMRRIMENYAKNVRFCLLCNYVNKITPAIQSRCTAFRFSPLKKEYMMNKALDIAKSENVNVTKEGLESLIRVGHGDMRRILNCLQVVSLSHKNLTIDENIILSTLDIPLPNEIKQILEHFMKNTIKESYEFVSELQYNKGYSIKDIMKCLYDMVLTYDFPDSAFCLLLKNFGEIEERCSSGANEQITLSALISSFVEFREELFKLKYDIKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQS3</accession>
    <name>A0A1J1GQS3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Enkurin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00226000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527678.1">
        <property type="nucleotide sequence ID" value="XM_028670980.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQS3"/>
    <dbReference type="GeneID" id="39730787"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00226000"/>
    <dbReference type="OMA" id="HRVIYIA"/>
    <dbReference type="OrthoDB" id="2123594at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027012">
        <property type="entry name" value="Enkurin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052102">
        <property type="entry name" value="Enkurin_domain-protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21490:SF0">
        <property type="entry name" value="ENKURIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21490">
        <property type="entry name" value="ENKURIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13864">
        <property type="entry name" value="Enkurin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51665">
        <property type="entry name" value="ENKURIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enkurin" evidence="7">
        <location>
            <begin position="186"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="209"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="271" mass="32308" checksum="C8D7B25C0080B8F2" modified="2017-02-15" version="1">MEDYEKLFEDMKLEEDNAYNIIKKSEEKKIKRILYKSKHDPNVLPSYSTFNLKGKRYNISNVTGMLIKKEEKQKSITELKNSYNKKILKKGEKNQMIPSLNEIKKVNPAILTVKKKKKKFKDPLPDRNDNPLLNLRDEEIDYIYDNAVEVIHTKPVEKKKRQGKILLDENPLDKKDYGKISPYLIKIKNELKEKENLKKQDIIDEEKTAKEIEEKRNILLMELKNKYNEINKEYLKISHVVDVNSVRKLKKKENYEKQLNQLEKDIQKLET</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQT3</accession>
    <name>A0A1J1GQT3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">50S ribosomal protein L22, apicoplast, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">L22</name>
        <name evidence="5" type="ORF">PGAL8A_00226800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527686.1">
        <property type="nucleotide sequence ID" value="XM_028670989.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQT3"/>
    <dbReference type="GeneID" id="39730795"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00226800"/>
    <dbReference type="OrthoDB" id="1840754at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.470.10:FF:000014">
        <property type="entry name" value="50S ribosomal protein L22, apicoplast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.10">
        <property type="entry name" value="Ribosomal protein L22/L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001063">
        <property type="entry name" value="Ribosomal_uL22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047867">
        <property type="entry name" value="Ribosomal_uL22_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018260">
        <property type="entry name" value="Ribosomal_uL22_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036394">
        <property type="entry name" value="Ribosomal_uL22_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13501">
        <property type="entry name" value="CHLOROPLAST 50S RIBOSOMAL PROTEIN L22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13501:SF10">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL22M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00237">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54843">
        <property type="entry name" value="Ribosomal protein L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00464">
        <property type="entry name" value="RIBOSOMAL_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="279" mass="33378" checksum="1EC0B8FC8C3833AA" modified="2017-02-15" version="1">MFILQVILDHSIYVYNFTINNKKKITYLKYGNQIMNRGGIIPFKDPKKKYYNVSFLLRTTSEIQEENKLSETFCKMENINEKESSLFDEMDLFHNEGIQLKQWYSAQKVKEAWKEKHIENIKSNYKKVLLNNKYNELFNMYRNVNNNNVENYKKRVKTNRINPVIYVKKRLVSATAKYIKMSFIKTRKILWKIRYMPIIKAFAFLYYYGTNKYTVNIYKCIKSCLHNAINKYGKNNIKPVFHTLQANMGGYTKKINIRAKGKTDIIREPHTHIRVVLEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQT8</accession>
    <name>A0A1J1GQT8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mitochondrial pyruvate carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">MPC2</name>
        <name evidence="10" type="ORF">PGAL8A_00229900</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Mediates the uptake of pyruvate into mitochondria.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion inner membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527716.1">
        <property type="nucleotide sequence ID" value="XM_028671022.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQT8"/>
    <dbReference type="GeneID" id="39730826"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00229900"/>
    <dbReference type="OMA" id="PQQFAIC"/>
    <dbReference type="OrthoDB" id="869189at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006850">
        <property type="term" value="P:pyruvate import into mitochondria"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005336">
        <property type="entry name" value="MPC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14154">
        <property type="entry name" value="UPF0041 BRAIN PROTEIN 44-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03650">
        <property type="entry name" value="MPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG94902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="135" mass="15687" checksum="CA026EF1C0502101" modified="2017-02-15" version="1">MSLIKKIFYPNIIPKIKNRIECYNINHNIKNALVSDTGLLSIHFWAPTFKWSISLANLAEINRDANILSLPQQFAIFFTGLLFSRFAYVVKPRNYNLLTINLFMSLTALYQITRIANCKYNLKMKDKINNPISKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQV5</accession>
    <name>A0A1J1GQV5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13">Fructose-bisphosphate aldolase</fullName>
            <ecNumber evidence="6 13">4.1.2.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PGAL8A_00204000</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:14729"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 14">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Host cell membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 13">Belongs to the class I fructose-bisphosphate aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.13" evidence="6 13"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527459.1">
        <property type="nucleotide sequence ID" value="XM_028670736.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQV5"/>
    <dbReference type="GeneID" id="39730567"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00204000"/>
    <dbReference type="OMA" id="WRAVITI"/>
    <dbReference type="OrthoDB" id="36455at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00183"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020002">
        <property type="term" value="C:host cell plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004332">
        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051289">
        <property type="term" value="P:protein homotetramerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00948">
        <property type="entry name" value="FBP_aldolase_I_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000187">
        <property type="entry name" value="Fructose-bisphosphate aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029768">
        <property type="entry name" value="Aldolase_I_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000741">
        <property type="entry name" value="FBA_I"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF033379">
        <property type="entry name" value="FrucBisAld_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11627">
        <property type="entry name" value="FRUCTOSE-BISPHOSPHATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00274">
        <property type="entry name" value="Glycolytic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00158">
        <property type="entry name" value="ALDOLASE_CLASS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 13" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="8" id="KW-1032">Host cell membrane</keyword>
    <keyword evidence="9" id="KW-1043">Host membrane</keyword>
    <keyword evidence="11 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0704">Schiff base</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG94644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="369" mass="39784" checksum="0B156E7AD80CD760" modified="2017-02-15" version="1">MAASTEYRNTPLKLPADVAEELATTAKNLVAPGKGILAADESTQTIKKRFDTIKLENTIENRASYRDLLFGTKGLGKFISGAILFEETLFQKNEGGTPLVNLLHNEGIIPGIKVDKGLVPIPCTDDEKATQGLDGLADRCKEYYKAGARFAKWRAVLVIDPAKGKPTDLSINETAWGLARYAAICQQNRLVPIVEPEILADGAHTIEVCANVTQKVLSCVFKALNDNGVLLEGALLKPNMVTAGYECPKPAKTQDVGFFTVRTLRRTVPPALPGVVFLSGGQSEEEASINLNSINASGPHPWALTFSYGRALQASVLNTWKGKKENVAKAREVLLQRAEANSLATCGKYKGGAGGENAATSLYEKKYVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQV9</accession>
    <name>A0A1J1GQV9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase</fullName>
            <ecNumber evidence="10">2.7.8.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">PGPS</name>
        <name evidence="12" type="ORF">PGAL8A_00113200</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>a CDP-1,2-diacyl-sn-glycerol + sn-glycerol 3-phosphate = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycero-3'-phosphate) + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12593"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:60110"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="2.7.8.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Phospholipid metabolism; phosphatidylglycerol biosynthesis; phosphatidylglycerol from CDP-diacylglycerol: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the CDP-alcohol phosphatidyltransferase class-II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.5" evidence="10"/>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526248.1">
        <property type="nucleotide sequence ID" value="XM_028674110.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQV9"/>
    <dbReference type="GeneID" id="39729657"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00113200"/>
    <dbReference type="OMA" id="NYGYRAT"/>
    <dbReference type="OrthoDB" id="10250191at2759"/>
    <dbReference type="UniPathway" id="UPA00084">
        <property type="reaction ID" value="UER00503"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008444">
        <property type="term" value="F:CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032049">
        <property type="term" value="P:cardiolipin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09135">
        <property type="entry name" value="PLDc_PGS1_euk_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09137">
        <property type="entry name" value="PLDc_PGS1_euk_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016270">
        <property type="entry name" value="PGS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12586:SF1">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12586">
        <property type="entry name" value="CDP-DIACYLGLYCEROL--SERINE O-PHOSPHATIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 10" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="11">
        <location>
            <begin position="126"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG93426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="634" mass="74566" checksum="19ED7D6710B1DBCA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR54</accession>
    <name>A0A1J1GR54_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00145700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526573.1">
        <property type="nucleotide sequence ID" value="XM_028674997.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR54"/>
    <dbReference type="GeneID" id="39729981"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00145700"/>
    <dbReference type="OMA" id="KFMDELM"/>
    <dbReference type="OrthoDB" id="378291at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="98"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="976"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="370"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="800"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="989"/>
            <end position="1001"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1255" mass="151774" checksum="E6E7B295E4770B4A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR72</accession>
    <name>A0A1J1GR72_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00236200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527778.1">
        <property type="nucleotide sequence ID" value="XM_028671092.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730890"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00236200"/>
    <dbReference type="OMA" id="RNYRARE"/>
    <dbReference type="OrthoDB" id="378415at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="634"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="673"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1275"/>
            <end position="1292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1312"/>
            <end position="1331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="4093" mass="499762" checksum="9BC887A0EDFBD920" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRF9</accession>
    <name>A0A1J1GRF9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Amino acid transporter, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00158000</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amino acid/polyamine transporter 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526693.1">
        <property type="nucleotide sequence ID" value="XM_028675131.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRF9"/>
    <dbReference type="GeneID" id="39730105"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00158000"/>
    <dbReference type="OMA" id="YHKTIID"/>
    <dbReference type="OrthoDB" id="438545at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061459">
        <property type="term" value="F:L-arginine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005313">
        <property type="term" value="F:L-glutamate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005290">
        <property type="term" value="F:L-histidine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015189">
        <property type="term" value="F:L-lysine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015194">
        <property type="term" value="F:L-serine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005302">
        <property type="term" value="F:L-tyrosine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF678">
        <property type="entry name" value="VACUOLAR AMINO ACID TRANSPORTER 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="200"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="273"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="311"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="393"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="431"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="456"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="522"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="545"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="579"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="11">
        <location>
            <begin position="169"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG93872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="606" mass="70057" checksum="0E7C979A56FB2625" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRG2</accession>
    <name>A0A1J1GRG2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00249700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527910.1">
        <property type="nucleotide sequence ID" value="XM_028671238.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRG2"/>
    <dbReference type="GeneID" id="39731025"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00249700"/>
    <dbReference type="OrthoDB" id="390891at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="605" mass="71526" checksum="6F5563A8A0D2A351" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRK3</accession>
    <name>A0A1J1GRK3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00254200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527950.1">
        <property type="nucleotide sequence ID" value="XM_028671282.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRK3"/>
    <dbReference type="GeneID" id="39731070"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00254200"/>
    <dbReference type="OMA" id="WIKQSEN"/>
    <dbReference type="OrthoDB" id="390600at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="313" mass="37292" checksum="E8E2E45D8F85BF6A" modified="2017-02-15" version="1">MKSNFQNEPFKEDNYIKAWIKQSENPELYKDFNDLEDESCTNEFIKVVDFNNFNSNFINTIMKEHSPEKIKENKKRKAYCLFYNSEIESESNYYNDEHKNYNNIYSSYEDTEIKYFKPLDKTPSCDMKDRQIHHYKDENLSIKKLKRENVCSENNYDIFCHNLMDSSPYLKLKQCNKPNYGSESTSEFFNNYEFETPIKVLRSKEKSYDIKNKKDNSTNTTKENSYQENVSSNNSETKRTINFSNKTEDFNDLQSNSDNEYLTSSEYVDEEDLSRYGQKKQSEVNFLGQKLDYKVVGNVINCSKDHPRFTILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRM8</accession>
    <name>A0A1J1GRM8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">1-deoxy-D-xylulose-5-phosphate synthase</fullName>
            <ecNumber evidence="6">2.2.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">DXS</name>
        <name evidence="15" type="ORF">PGAL8A_00248100</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Metabolic intermediate biosynthesis; 1-deoxy-D-xylulose 5-phosphate biosynthesis; 1-deoxy-D-xylulose 5-phosphate from D-glyceraldehyde 3-phosphate and pyruvate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the transketolase family. DXPS subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.7" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527895.1">
        <property type="nucleotide sequence ID" value="XM_028671221.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRM8"/>
    <dbReference type="GeneID" id="39731009"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00248100"/>
    <dbReference type="OMA" id="IFISPAM"/>
    <dbReference type="OrthoDB" id="10266385at2759"/>
    <dbReference type="UniPathway" id="UPA00064">
        <property type="reaction ID" value="UER00091"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008661">
        <property type="term" value="F:1-deoxy-D-xylulose-5-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07033">
        <property type="entry name" value="TPP_PYR_DXS_TK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005477">
        <property type="entry name" value="Dxylulose-5-P_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020826">
        <property type="entry name" value="Transketolase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43322">
        <property type="entry name" value="1-D-DEOXYXYLULOSE 5-PHOSPHATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43322:SF5">
        <property type="entry name" value="1-DEOXY-D-XYLULOSE-5-PHOSPHATE SYNTHASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13292">
        <property type="entry name" value="DXP_synthase_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00802">
        <property type="entry name" value="TRANSKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="11" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="7 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="14">
        <location>
            <begin position="736"/>
            <end position="902"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG95082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1079" mass="125753" checksum="6AAC448EA96A461D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRS2</accession>
    <name>A0A1J1GRS2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00143600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526552.1">
        <property type="nucleotide sequence ID" value="XM_028674974.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRS2"/>
    <dbReference type="GeneID" id="39729960"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00143600"/>
    <dbReference type="OMA" id="PIIYVPT"/>
    <dbReference type="OrthoDB" id="5970161at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716:SF4">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 245"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="221"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="245"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="301"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="637"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="712"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="739"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="768"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="804"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="844"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="844"/>
            <end position="862"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1034" mass="125096" checksum="45F208EE99C48BEF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRS3</accession>
    <name>A0A1J1GRS3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nucleoporin NUP205</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00170700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526821.1">
        <property type="nucleotide sequence ID" value="XM_028670028.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730234"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00170700"/>
    <dbReference type="OMA" id="DESCFIM"/>
    <dbReference type="OrthoDB" id="378784at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071763">
        <property type="term" value="P:nuclear membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33416">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33416:SF20">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="573"/>
            <end position="607"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1695" mass="195451" checksum="9E5B183B53C4BBD4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRT9</accession>
    <name>A0A1J1GRT9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00263100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528038.1">
        <property type="nucleotide sequence ID" value="XM_028671380.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731160"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00263100"/>
    <dbReference type="OrthoDB" id="1696305at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050896">
        <property type="entry name" value="Mito_lipid_metab_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46434">
        <property type="entry name" value="GENETIC INTERACTOR OF PROHIBITINS 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46434:SF1">
        <property type="entry name" value="GENETIC INTERACTOR OF PROHIBITINS 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009618933" description="G domain-containing protein" evidence="3">
        <location>
            <begin position="22"/>
            <end position="1714"/>
        </location>
    </feature>
    <feature type="domain" description="G" evidence="4">
        <location>
            <begin position="1477"/>
            <end position="1539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="347"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="540"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1063"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="203"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="361"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="380"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="463"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="514"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="558"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1714" mass="206577" checksum="3B3E73223A916C71" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRV3</accession>
    <name>A0A1J1GRV3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00173900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526853.1">
        <property type="nucleotide sequence ID" value="XM_028670063.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRV3"/>
    <dbReference type="GeneID" id="39730266"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00173900"/>
    <dbReference type="OMA" id="CEKIAHT"/>
    <dbReference type="OrthoDB" id="392571at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000480">
        <property type="term" value="P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000472">
        <property type="term" value="P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000056">
        <property type="term" value="P:ribosomal small subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040000">
        <property type="entry name" value="NOP9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13102">
        <property type="entry name" value="NUCLEOLAR PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13102:SF0">
        <property type="entry name" value="NUCLEOLAR PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22493">
        <property type="entry name" value="PUF_NOP9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="913"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1006"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="921"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1007"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1018"/>
            <end position="1030"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1030" mass="123534" checksum="38F6014D0828DFC2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS18</accession>
    <name>A0A1J1GS18_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00154400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526656.1">
        <property type="nucleotide sequence ID" value="XM_028675090.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS18"/>
    <dbReference type="GeneID" id="39730068"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00154400"/>
    <dbReference type="OMA" id="ICEYFAY"/>
    <dbReference type="OrthoDB" id="377101at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="311" mass="36514" checksum="B86586CCF27A40E3" modified="2017-02-15" version="1">MKAGYTSIGNKIEKKISKKNEGNSNIKKFFFFQKKNGKNKFYGERFKLKINKKKEKNTSNLNAQNNTNNLQGIIDKSKSANTDEINEDNHLEEKSKINNEKKIKSIKINFNNHIKKSVSSKFYFEGDNNKLPKLSNNYSFKKTELFPKNKIELSMKNIKEISDSLKSENIYESDSYGKFFEINNEAKRELSEHVKTLIISKNDSNIDFKTKEIFSDDEESEYQNFNKLKTLYESAHATTRFFLTKIINSKEYIERNIPLYDDILNKNSESLFKKLDIFDEDEKVDNCEQGYDIVDSICEYFTYLMSLTLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS84</accession>
    <name>A0A1J1GS84_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RAP protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00161500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526728.1">
        <property type="nucleotide sequence ID" value="XM_028675170.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS84"/>
    <dbReference type="GeneID" id="39730140"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00161500"/>
    <dbReference type="OMA" id="HMLYKSI"/>
    <dbReference type="OrthoDB" id="9985850at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013584">
        <property type="entry name" value="RAP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08373">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00952">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51286">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RAP" evidence="1">
        <location>
            <begin position="818"/>
            <end position="876"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="943" mass="111772" checksum="24F114B02C53A9D2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSE1</accession>
    <name>A0A1J1GSE1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Protein kinase, putative</fullName>
            <ecNumber evidence="9">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00010700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="9"/>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528151.1">
        <property type="nucleotide sequence ID" value="XM_028671505.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728629"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00010700"/>
    <dbReference type="OrthoDB" id="10252171at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE PLK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24345:SF91">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE PLK4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="158"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="523"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1156"/>
            <end position="1186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2871"/>
            <end position="2891"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1256"/>
            <end position="1336"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="2059"/>
            <end position="2129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="532"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG95340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2975" mass="352052" checksum="950CEF0BD6CA24E4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSU1</accession>
    <name>A0A1J1GSU1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Transporter, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00011700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC43A transporter (TC 2.A.1.44) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528161.1">
        <property type="nucleotide sequence ID" value="XM_028671516.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSU1"/>
    <dbReference type="GeneID" id="39728639"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00011700"/>
    <dbReference type="OMA" id="FFANHMY"/>
    <dbReference type="OrthoDB" id="371800at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052599">
        <property type="entry name" value="SLC43A_AATransporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20772">
        <property type="entry name" value="PROTEIN FMP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20772:SF2">
        <property type="entry name" value="PROTEIN FMP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="209"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="416"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="451"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="478"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="505"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="538"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="569"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="359"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG95350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="605" mass="71598" checksum="56A25E1E16C85EDA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT62</accession>
    <name>A0A1J1GT62_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glycine--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Diadenosine tetraphosphate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00292200</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.14" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528526.1">
        <property type="nucleotide sequence ID" value="XM_028671922.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT62"/>
    <dbReference type="GeneID" id="39731455"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00292200"/>
    <dbReference type="OMA" id="HFVNFQR"/>
    <dbReference type="OrthoDB" id="57698at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004820">
        <property type="term" value="F:glycine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070150">
        <property type="term" value="P:mitochondrial glycyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00774">
        <property type="entry name" value="GlyRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000091">
        <property type="entry name" value="Glycine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.720.200:FF:000001">
        <property type="entry name" value="Glycine--tRNA ligase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.800:FF:000004">
        <property type="entry name" value="Glycine--tRNA ligase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.720.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027031">
        <property type="entry name" value="Gly-tRNA_synthase/POLG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033731">
        <property type="entry name" value="GlyRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002315">
        <property type="entry name" value="tRNA-synt_gly"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00389">
        <property type="entry name" value="glyS_dimeric"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003211">
        <property type="entry name" value="PRK04173.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10745:SF0">
        <property type="entry name" value="GLYCINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10745">
        <property type="entry name" value="GLYCYL-TRNA SYNTHETASE/DNA POLYMERASE SUBUNIT GAMMA-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01043">
        <property type="entry name" value="TRNASYNTHGLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="12">
        <location>
            <begin position="364"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="68"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="240"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG95718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="809" mass="94757" checksum="C46B717F95E3FB28" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTC9</accession>
    <name>A0A1J1GTC9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="5">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PP7</name>
        <name evidence="7" type="ORF">PGAL8A_00295100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the PPP phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528554.1">
        <property type="nucleotide sequence ID" value="XM_028671952.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTC9"/>
    <dbReference type="GeneID" id="39731484"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00295100"/>
    <dbReference type="OMA" id="EWKNECF"/>
    <dbReference type="OrthoDB" id="445564at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051134">
        <property type="entry name" value="PPP_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45668">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45668:SF5">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00015">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="639"/>
            <end position="674"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="957" mass="112259" checksum="A6719ABA679D7067" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTG1</accession>
    <name>A0A1J1GTG1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00404300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527160.1">
        <property type="nucleotide sequence ID" value="XM_028670404.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732573"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00404300"/>
    <dbReference type="OMA" id="HECMNFD"/>
    <dbReference type="OrthoDB" id="377941at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="565"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="657"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="725"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="836"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1549"/>
            <end position="1568"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="444"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1190"/>
            <end position="1221"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1245"/>
            <end position="1272"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1426"/>
            <end position="1453"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1895"/>
            <end position="1930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1549"/>
            <end position="1567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1944" mass="234904" checksum="8E2DE0B4C9AF0847" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTJ7</accession>
    <name>A0A1J1GTJ7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Exodeoxyribonuclease III, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00302200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="5">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="5">Probably binds two magnesium or manganese ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA repair enzymes AP/ExoA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528618.1">
        <property type="nucleotide sequence ID" value="XM_028672024.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTJ7"/>
    <dbReference type="GeneID" id="39731555"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00302200"/>
    <dbReference type="OMA" id="CWDTYKQ"/>
    <dbReference type="OrthoDB" id="391817at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003906">
        <property type="term" value="F:DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008311">
        <property type="term" value="F:double-stranded DNA 3'-5' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004808">
        <property type="entry name" value="AP_endonuc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748">
        <property type="entry name" value="AP ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748:SF6">
        <property type="entry name" value="DNA-(APURINIC OR APYRIMIDINIC SITE) ENDONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="7">
        <location>
            <begin position="7"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="260"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="6">
        <location>
            <position position="650"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604808-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR604808-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="855" mass="101562" checksum="AFDD8EA4DB744438" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTV8</accession>
    <name>A0A1J1GTV8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CCAAT-box DNA binding protein subunit B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00287200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528483.1">
        <property type="nucleotide sequence ID" value="XM_028671874.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTV8"/>
    <dbReference type="GeneID" id="39731405"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00287200"/>
    <dbReference type="OMA" id="SEHTDYC"/>
    <dbReference type="OrthoDB" id="372172at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="773"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="815"/>
            <end position="837"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="849" mass="102102" checksum="3A4FED8D6616C0D4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU03</accession>
    <name>A0A1J1GU03_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00314800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528743.1">
        <property type="nucleotide sequence ID" value="XM_028672162.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731681"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00314800"/>
    <dbReference type="OrthoDB" id="378198at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048024">
        <property type="term" value="P:regulation of mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052225">
        <property type="entry name" value="Ser/Arg_repetitive_matrix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23148">
        <property type="entry name" value="SERINE/ARGININE REGULATED NUCLEAR MATRIX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23148:SF0">
        <property type="entry name" value="SERINE_ARGININE REPETITIVE MATRIX PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="288"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="4">
        <location>
            <begin position="2048"/>
            <end position="2073"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="2048"/>
            <end position="2073"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="448"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1916"/>
            <end position="1949"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2165"/>
            <end position="2214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2235"/>
            <end position="2259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="448"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1916"/>
            <end position="1926"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3112" mass="368896" checksum="7267D9AA47517461" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU33</accession>
    <name>A0A1J1GU33_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Mitochondrial ribosomal protein L15, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00301300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528609.1">
        <property type="nucleotide sequence ID" value="XM_028672014.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU33"/>
    <dbReference type="GeneID" id="39731546"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00301300"/>
    <dbReference type="OMA" id="DKCPGKG"/>
    <dbReference type="OrthoDB" id="361383at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.100.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_uL15/eL18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="Ribosomal_uL15/eL18_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005749">
        <property type="entry name" value="Ribosomal_uL15_bac-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934:SF11">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL15M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="Ribosomal proteins L15p and L18e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL15/eL18" evidence="5">
        <location>
            <begin position="173"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="106"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="329"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="128"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="329"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="374" mass="44897" checksum="0156D9A142EE7679" modified="2017-02-15" version="1">MIKNGKICNTLRKLLIVNKFPLCRHTSSQKYFEKENVKNASEENSNLKDSNNKLNWNLCELKIGKHFREMFHDGSEKNFESHPFNRRFAYSKKSFFPIEPRNLRSLGLNRQRKKKRGRGDKCPGKGIRDKHKHRKSGRPNSRTFESGRTPLYRRLPKWPEAWLSRQKKNYDCLNLSKLRYFIEKGRLDIRFPITQRHLHDSKCIKVKNGVKLFNVNDYPFPYKIDIEVSNADQSSIDVIKKVGGSVTIIYMERVNLRAHIKPYKFEILPKTARPNLDMIHFLERMRSKGCIVKYIKPLWLIEEEKRIINELTEMEENAKLCEEFDENKNTHKKEKVDKINDKEKIYEQEEDEDERRDRLLQKYRLQYTQMRKDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU65</accession>
    <name>A0A1J1GU65_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00328700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000057">
        <property type="protein sequence ID" value="CRG96073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528878.1">
        <property type="nucleotide sequence ID" value="XM_028672314.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU65"/>
    <dbReference type="GeneID" id="39731816"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00328700"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="236" mass="28325" checksum="AA745F3F92176B2F" modified="2017-02-15" version="1">MKTLTLYLKITTFLLLIWIYQCFYNCYSYKTLIDENILQKKNELKYERVLTEGKIAGKKQAYAVGYLEECPLDNKKKKWENPGQYKNPCDQWHNVITPLLRELFNKEASEMDPKLRDQKWNKEWNKISANKVNDLSAIFYRSDISEEEKRKLIRSVKEELHMEFVKFLGECRKEMRDNKTESESTKEMTENKTESESTKEIRENRTESECKKEMRENKAESKSKKEKGKKKIKNKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUA0</accession>
    <name>A0A1J1GUA0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00327400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000053">
        <property type="protein sequence ID" value="CRG96058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528866.1">
        <property type="nucleotide sequence ID" value="XM_028672300.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUA0"/>
    <dbReference type="GeneID" id="39731804"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00327400"/>
    <dbReference type="OrthoDB" id="6362699at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="285"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="318" mass="37747" checksum="01D5D3D91C231510" modified="2017-02-15" version="1">MTIFSNNDEDGILFLYEYNPYNNEYPEKTYLCRLSTTEQKITLCEAVNMEYLGRTLKFDSYDIVNEENNKKNISSLKNPNHKIIKSKYDKLLFKEYPYHHIKTKYISYYNKKNILCKKINNDNMECIDANYGGRLIFLDDGYYDLHKKYLYVPNNCLGENLNSSCSPYICDIQDTNEFVPCEYEEMSVVKNIRPINNIMPTKIIMPKKDMRPINEIIPCEDLMPCKYVRSYKHMLPPYNIIPLKGIRPIKNIGPNSKNPHAISLKNKDINHENRLNNSALFAMSFMSFLVIFIFFFCLLYRFLFFLNVIFIFILLKFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV22</accession>
    <name>A0A1J1GV22_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">PQ-loop repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00362500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MPDU1 (TC 2.A.43.3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529206.1">
        <property type="nucleotide sequence ID" value="XM_028672678.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV22"/>
    <dbReference type="GeneID" id="39732155"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00362500"/>
    <dbReference type="OMA" id="LQVLYYW"/>
    <dbReference type="OrthoDB" id="271506at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016817">
        <property type="entry name" value="MannP-dilichol_defect-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12226">
        <property type="entry name" value="MANNOSE-P-DOLICHOL UTILIZATION DEFECT 1 LEC35 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12226:SF2">
        <property type="entry name" value="MANNOSE-P-DOLICHOL UTILIZATION DEFECT 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF023381">
        <property type="entry name" value="MannP-dilichol_defect-1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="173"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="9">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG96401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="212" mass="24711" checksum="07673D58EC49B1A1" modified="2017-02-15" version="1" fragment="single">VLYDIFVNLIIVGSCFIKFPQIIKIIANKSVVGLSFLSLYLEILVASSLIVFSIKENINIKLFLDVILINAQNIFIVLLMWRYSNKYPKYINAIKISFYVFFNIYLIYWLPNVFVPFLGIVSAPISCFSKAPQIYLNYKNKNTGNLSLVTYIIVFLGNLGRIFTIFFSSNNKIYLIHCIFISTLNFTILYQIIYYWKNTKNISTQIKKEKHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVA5</accession>
    <name>A0A1J1GVA5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00361800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529199.1">
        <property type="nucleotide sequence ID" value="XM_028672670.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732148"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00361800"/>
    <dbReference type="OMA" id="HNGIHEN"/>
    <dbReference type="OrthoDB" id="383482at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052503">
        <property type="entry name" value="S100-fused_Epidermal_Struct"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22571:SF50">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22571">
        <property type="entry name" value="FILAGGRIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="179"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2013" mass="239033" checksum="52F164A1065C831A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVG9</accession>
    <name>A0A1J1GVG9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Acyl-CoA-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00345600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529043.1">
        <property type="nucleotide sequence ID" value="XM_028672496.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVG9"/>
    <dbReference type="GeneID" id="39731986"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00345600"/>
    <dbReference type="OMA" id="TMSKMKP"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000062">
        <property type="term" value="F:fatty-acyl-CoA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000582">
        <property type="entry name" value="Acyl-CoA-binding_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035984">
        <property type="entry name" value="Acyl-CoA-binding_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014352">
        <property type="entry name" value="FERM/acyl-CoA-bd_prot_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24119">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24119:SF0">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00887">
        <property type="entry name" value="ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47027">
        <property type="entry name" value="Acyl-CoA binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51228">
        <property type="entry name" value="ACB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="domain" description="ACB" evidence="6">
        <location>
            <begin position="76"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="252"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="4">
        <location>
            <begin position="285"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="329" mass="38271" checksum="8F5F6849C4986EED" modified="2017-02-15" version="1">MFRNISKPAFAFNVVSVVVIIYLLTSYRKKSHILDKLYDLKNWLFNGPFSFYKKYIKIKLPPIDKNITINISDEELEEKFSQTCNAVKIYRNKLKFEEWIYLYGLYKQITNGNIKLNNDEEIECNDYNNNENNNNKKKNDLKLSKNDYIENEKINSWKNCYDVDKKVCKFLYVEFFNKLFPNAIENLNSNLSFEFSKSISKMKSLKENNYTEDNTDNNLCDLLCHNVVFSNIEYVKKILDSHPHLISQKNSDGLTALHYACDRGHLEIAKLLVERGADINMEDSYGDTALHIAAYSDKKEIIDYLTSVGADIDKKNSDGLTVGSILNQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVP0</accession>
    <name>A0A1J1GVP0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00375000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529330.1">
        <property type="nucleotide sequence ID" value="XM_028672815.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVP0"/>
    <dbReference type="GeneID" id="39732280"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00375000"/>
    <dbReference type="OMA" id="CSGMDGY"/>
    <dbReference type="OrthoDB" id="375409at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="519" mass="62542" checksum="8D448DCA2D6B0B50" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVR9</accession>
    <name>A0A1J1GVR9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00000100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000069">
        <property type="protein sequence ID" value="CRG96558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529362.1">
        <property type="nucleotide sequence ID" value="XM_028672850.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728523"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00000100"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="563"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1021"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="131"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1524" mass="182632" checksum="1177DC892451734F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVT0</accession>
    <name>A0A1J1GVT0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Kelch protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00359000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529171.1">
        <property type="nucleotide sequence ID" value="XM_028672638.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732120"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00359000"/>
    <dbReference type="OrthoDB" id="10251809at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052124">
        <property type="entry name" value="Rab9_kelch_effector"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46647">
        <property type="entry name" value="RAB9 EFFECTOR PROTEIN WITH KELCH MOTIFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46647:SF1">
        <property type="entry name" value="RAB9 EFFECTOR PROTEIN WITH KELCH MOTIFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="971"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="2631"/>
            <end position="2665"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2797" mass="332524" checksum="36B8AD91D427D8E8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVT2</accession>
    <name>A0A1J1GVT2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00412800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000063">
        <property type="protein sequence ID" value="CRG96546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529351.1">
        <property type="nucleotide sequence ID" value="XM_028672838.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732658"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00412800"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="649"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="376"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="781"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="376"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="416"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="439"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="470"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="491"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="558"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="575"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="781"/>
            <end position="798"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1614" mass="191007" checksum="5119BFC03107639C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW88</accession>
    <name>A0A1J1GW88_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00004200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528088.1">
        <property type="nucleotide sequence ID" value="XM_028671436.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW88"/>
    <dbReference type="GeneID" id="39728564"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00004200"/>
    <dbReference type="OMA" id="HRKCACA"/>
    <dbReference type="OrthoDB" id="383683at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="170" mass="20861" checksum="BCF1605FFF7E312D" modified="2017-02-15" version="1">MGEQILYDNFPLIFLNNDENENFDDKNERDFRKEIKNIIEKLKLLRIEINEKYSIRSVLEEKLTILQKEEHVKQNNMKYIMNFSENNLYEREVLNYKNNIKYLKKQIKNSTCKIKLLLEKEFKVRKQLQLNYMALYDLLSERINYILNDYIKHRKCSCAIYAYQQENKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWB8</accession>
    <name>A0A1J1GWB8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Merozoite surface protein 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Merozoite surface antigen</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">PMMSA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="24" type="primary">MSP1</name>
        <name evidence="24" type="ORF">PGAL8A_00443200</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">During the asexual blood stage, involved in merozoite egress from host erythrocytes possibly via its interaction with the host cytoskeleton protein spectrin resulting in the destabilization of the host cytoskeleton and thus leading to erythrocyte cell membrane rupture. Involved in the binding to host erythrocytes and is required for host erythrocyte invasion.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
            <topology evidence="1">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529654.1">
        <property type="nucleotide sequence ID" value="XM_028673174.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732965"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00443200"/>
    <dbReference type="OMA" id="KLNDMCA"/>
    <dbReference type="OrthoDB" id="10045365at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010901">
        <property type="entry name" value="MSP1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024730">
        <property type="entry name" value="MSP1_EGF_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12946">
        <property type="entry name" value="EGF_MSP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07462">
        <property type="entry name" value="MSP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="18" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="14" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="11 20" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 24" id="KW-0477">Merozoite</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0964">Secreted</keyword>
    <keyword evidence="9 21" id="KW-0732">Signal</keyword>
    <keyword evidence="20" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="20" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="21">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012453009" description="Merozoite surface protein 1" evidence="21">
        <location>
            <begin position="20"/>
            <end position="1623"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="1595"/>
            <end position="1620"/>
        </location>
    </feature>
    <feature type="domain" description="Merozoite surface 1 C-terminal" evidence="22">
        <location>
            <begin position="896"/>
            <end position="1430"/>
        </location>
    </feature>
    <feature type="domain" description="Merozoite surface protein EGF" evidence="23">
        <location>
            <begin position="1520"/>
            <end position="1556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="627"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="820"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1147"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1173"/>
            <end position="1247"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="18">
        <location>
            <begin position="228"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="18">
        <location>
            <begin position="504"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="18">
        <location>
            <begin position="940"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="627"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="656"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="689"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="821"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="840"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="850"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="19">
        <location>
            <begin position="1147"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="1182"/>
            <end position="1203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="19">
        <location>
            <begin position="1204"/>
            <end position="1213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="1217"/>
            <end position="1247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00031689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00032276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00045963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF07462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF12946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="CRG96851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1623" mass="187988" checksum="E113C28AEFF3F692" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWC1</accession>
    <name>A0A1J1GWC1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-i protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00000200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000069">
        <property type="protein sequence ID" value="CRG96559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529363.1">
        <property type="nucleotide sequence ID" value="XM_028672851.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWC1"/>
    <dbReference type="GeneID" id="39728524"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00000200"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="121"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="235" mass="28021" checksum="7063EA533546CCC9" modified="2017-02-15" version="1">MDLNLSDIIYIDSCETLDEEDSTEGFAHREIKDATVSIPENPLHDNLNSPDAIQNPSKDINLDSATSTNLLDKKSLSIFQLVIIIISFLRFKRTYSLKLKAKNEMNVRLQKILHNSNKKMKGDLEKEMQKEKKKMEDDQKKLLKKKKEIEVQEKGVLRRKEEWEEIKLKEKHGYDKSILKHLEEREKRILKRGEDWKKRTLKEKIKLDKKMRKNKEEGEKRMLEIIEKFEKEMLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWR4</accession>
    <name>A0A1J1GWR4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cilia- and flagella-associated protein 61 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00457500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529798.1">
        <property type="nucleotide sequence ID" value="XM_028673336.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733108"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00457500"/>
    <dbReference type="OMA" id="HFQENNH"/>
    <dbReference type="OrthoDB" id="382863at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038884">
        <property type="entry name" value="CFAP61"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21178">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21178:SF8">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1858" mass="224545" checksum="B4C40DA7BB74DFAD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWW1</accession>
    <name>A0A1J1GWW1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Parasitophorous vacuolar protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00438700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529609.1">
        <property type="nucleotide sequence ID" value="XM_028673125.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWW1"/>
    <dbReference type="GeneID" id="39732920"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00438700"/>
    <dbReference type="OMA" id="LCRCTKY"/>
    <dbReference type="OrthoDB" id="391128at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="Lipocalins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013380426" description="Parasitophorous vacuolar protein 5" evidence="1">
        <location>
            <begin position="19"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="206" mass="23920" checksum="3690531400AD1C9E" modified="2017-02-15" version="1">MIKLIFYIFLLMSYVVIGKNDGNLRVITKNIDLKSLQGTFYEIAINTTDKIFLGLACRCTKYEFSGLKRDGNQAYILMNFTCDRNFLIKEEKSNVNFKLILNKPLDENTTTVEEFDASLFLVENNQQILLSNHISIIYAEFNDQNEIEHFILGGNKSSEPMIIMSKYRTILQETYKRLINSLYLSGYESALLNWPFIIQTDQTLCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX08</accession>
    <name>A0A1J1GX08_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">GPI mannosyltransferase 2</fullName>
            <ecNumber evidence="11">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00468000</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the PIGV family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="11"/>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529902.1">
        <property type="nucleotide sequence ID" value="XM_028673451.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX08"/>
    <dbReference type="GeneID" id="39733213"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00468000"/>
    <dbReference type="OMA" id="GALFIWC"/>
    <dbReference type="OrthoDB" id="10252502at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031501">
        <property type="term" value="C:mannosyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000009">
        <property type="term" value="F:alpha-1,6-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004376">
        <property type="term" value="F:GPI mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007315">
        <property type="entry name" value="PIG-V/Gpi18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12468">
        <property type="entry name" value="GPI MANNOSYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12468:SF2">
        <property type="entry name" value="GPI MANNOSYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04188">
        <property type="entry name" value="Mannosyl_trans2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 11 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4 11" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="125"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="298"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="345"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="406"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="436"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="463"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="488"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG97099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="513" mass="61821" checksum="B290261F6FFD85F8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX82</accession>
    <name>A0A1J1GX82_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00474000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000087">
        <property type="protein sequence ID" value="CRG97161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529964.1">
        <property type="nucleotide sequence ID" value="XM_028673519.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX82"/>
    <dbReference type="GeneID" id="39733273"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00474000"/>
    <dbReference type="OMA" id="THITYES"/>
    <dbReference type="OrthoDB" id="348930at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="483"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="774"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="289"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="324"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="389"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="484"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="502"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="532"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="553"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="572"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="590"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="618"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="659"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="672"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="702"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="782"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="808"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="808" mass="87610" checksum="EFA7CB502474A7A9" modified="2017-02-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXH1</accession>
    <name>A0A1J1GXH1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dynein regulatory complex subunit 7 MORN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00451600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529739.1">
        <property type="nucleotide sequence ID" value="XM_028673269.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXH1"/>
    <dbReference type="GeneID" id="39733049"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00451600"/>
    <dbReference type="OMA" id="AYVVCGE"/>
    <dbReference type="OrthoDB" id="10262874at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031514">
        <property type="term" value="C:motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048870">
        <property type="term" value="P:cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033551">
        <property type="entry name" value="DRC7/lobo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056291">
        <property type="entry name" value="MORN_DRC7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35249">
        <property type="entry name" value="DYNEIN REGULATORY COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35249:SF2">
        <property type="entry name" value="DYNEIN REGULATORY COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24667">
        <property type="entry name" value="MORN_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynein regulatory complex subunit 7 MORN" evidence="2">
        <location>
            <begin position="325"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="578"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="713" mass="86981" checksum="CABFD59E8B07E654" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXR7</accession>
    <name>A0A1J1GXR7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sec1 family protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00493500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the STXBP/unc-18/SEC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530158.1">
        <property type="nucleotide sequence ID" value="XM_028673735.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXR7"/>
    <dbReference type="GeneID" id="39733468"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00493500"/>
    <dbReference type="OMA" id="TMNIHIH"/>
    <dbReference type="OrthoDB" id="10251230at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.830.10">
        <property type="entry name" value="Syntaxin Binding Protein 1, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043154">
        <property type="entry name" value="Sec-1-like_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043127">
        <property type="entry name" value="Sec-1-like_dom3a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001619">
        <property type="entry name" value="Sec1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027482">
        <property type="entry name" value="Sec1-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036045">
        <property type="entry name" value="Sec1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11679">
        <property type="entry name" value="VESICLE PROTEIN SORTING-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00995">
        <property type="entry name" value="Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005715">
        <property type="entry name" value="VPS45_Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56815">
        <property type="entry name" value="Sec1/munc18-like (SM) proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="319"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="621" mass="72100" checksum="E153C233B8141AFA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY11</accession>
    <name>A0A1J1GY11_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00338600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528973.1">
        <property type="nucleotide sequence ID" value="XM_028672418.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY11"/>
    <dbReference type="GeneID" id="39731916"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00338600"/>
    <dbReference type="OMA" id="CYVVSFW"/>
    <dbReference type="OrthoDB" id="372380at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="768" mass="92500" checksum="A4B136760A632701" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY72</accession>
    <name>A0A1J1GY72_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">H(+)-transporting two-sector ATPase</fullName>
            <ecNumber evidence="2">7.1.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PGAL8A_00508100</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O + 4 H(+)(in) = ADP + phosphate + 5 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530309.1">
        <property type="nucleotide sequence ID" value="XM_028673903.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY72"/>
    <dbReference type="GeneID" id="39733614"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00508100"/>
    <dbReference type="OMA" id="RIVKTFW"/>
    <dbReference type="OrthoDB" id="1676488at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033180">
        <property type="term" value="C:proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046034">
        <property type="term" value="P:ATP metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18111">
        <property type="entry name" value="ATP-synt_V_A-type_alpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18119">
        <property type="entry name" value="ATP-synt_V_A-type_alpha_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01134">
        <property type="entry name" value="V_A-ATPase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1140.10:FF:000002">
        <property type="entry name" value="V-type proton ATPase catalytic subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.20:FF:000009">
        <property type="entry name" value="V-type proton ATPase catalytic subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000008">
        <property type="entry name" value="V-type proton ATPase catalytic subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000052">
        <property type="entry name" value="V-type proton ATPase catalytic subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1140.10">
        <property type="entry name" value="Bovine Mitochondrial F1-atpase, Atp Synthase Beta Chain, Chain D, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00309">
        <property type="entry name" value="ATP_synth_A_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055190">
        <property type="entry name" value="ATP-synt_VA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031686">
        <property type="entry name" value="ATP-synth_a_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024034">
        <property type="entry name" value="ATPase_F1/V1_b/a_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005725">
        <property type="entry name" value="ATPase_V1-cplx_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022878">
        <property type="entry name" value="V-ATPase_asu"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003220">
        <property type="entry name" value="PRK04192.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01042">
        <property type="entry name" value="V-ATPase_V1_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43607:SF1">
        <property type="entry name" value="H(+)-TRANSPORTING TWO-SECTOR ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43607">
        <property type="entry name" value="V-TYPE PROTON ATPASE CATALYTIC SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16886">
        <property type="entry name" value="ATP-synt_ab_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22919">
        <property type="entry name" value="ATP-synt_VA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47917">
        <property type="entry name" value="C-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="N-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-1278">Translocase</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit N-terminal" evidence="11">
        <location>
            <begin position="14"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="ATPsynthase alpha/beta subunit barrel-sandwich" evidence="12">
        <location>
            <begin position="118"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding" evidence="10">
        <location>
            <begin position="224"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="ATP synthase A/B type C-terminal" evidence="13">
        <location>
            <begin position="458"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF16886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF22919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG97508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="611" mass="68661" checksum="DB6659D51BBE12AD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYH7</accession>
    <name>A0A1J1GYH7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">S-antigen protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00494600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">S antigens are soluble heat-stable proteins present in the sera of some infected individuals.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Parasitophorous vacuole</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530169.1">
        <property type="nucleotide sequence ID" value="XM_028673747.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733479"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00494600"/>
    <dbReference type="OMA" id="KKTTHEP"/>
    <dbReference type="OrthoDB" id="392935at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020003">
        <property type="term" value="C:symbiont-containing vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008825">
        <property type="entry name" value="S-antigen"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05756">
        <property type="entry name" value="S-antigen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012046044" description="S-antigen protein" evidence="6">
        <location>
            <begin position="25"/>
            <end position="2024"/>
        </location>
    </feature>
    <feature type="domain" description="S-antigen" evidence="7">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="41"/>
            <end position="1986"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="41"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="126"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="203"/>
            <end position="217"/>
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    </feature>
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            <begin position="227"/>
            <end position="265"/>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
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            <begin position="277"/>
            <end position="287"/>
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    <feature type="compositionally biased region" description="Low complexity" evidence="5">
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            <begin position="394"/>
            <end position="408"/>
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    </feature>
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        <location>
            <begin position="423"/>
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        <location>
            <begin position="440"/>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="489"/>
            <end position="507"/>
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    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="520"/>
            <end position="529"/>
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    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="530"/>
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    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="605"/>
            <end position="616"/>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="623"/>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="684"/>
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        <location>
            <begin position="720"/>
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        <location>
            <begin position="747"/>
            <end position="763"/>
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        <location>
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            <begin position="1275"/>
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        <location>
            <begin position="1403"/>
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    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
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            <begin position="1442"/>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1456"/>
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    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1505"/>
            <end position="1518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1530"/>
            <end position="1551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1561"/>
            <end position="1578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1585"/>
            <end position="1594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1609"/>
            <end position="1626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1631"/>
            <end position="1656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1663"/>
            <end position="1676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="1677"/>
            <end position="1686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1715"/>
            <end position="1747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1753"/>
            <end position="1771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1779"/>
            <end position="1791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1814"/>
            <end position="1885"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1886"/>
            <end position="1919"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1932"/>
            <end position="1964"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1976"/>
            <end position="1986"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2024" mass="223697" checksum="54C771EDF2F6E73D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYN8</accession>
    <name>A0A1J1GYN8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Histone acetyltransferase subunit NuA4, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00526600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EAF6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530491.1">
        <property type="nucleotide sequence ID" value="XM_028674105.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYN8"/>
    <dbReference type="GeneID" id="39733799"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00526600"/>
    <dbReference type="OMA" id="EYHQNCN"/>
    <dbReference type="OrthoDB" id="440324at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000123">
        <property type="term" value="C:histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015418">
        <property type="entry name" value="Eaf6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09340">
        <property type="entry name" value="NuA4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="6"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG97690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="98" mass="11567" checksum="AADAE071AD2E1A4C" modified="2017-02-15" version="1">MKHKVKRDIIKCKKKLENSIKALEEKILRLESEYHQNCNVNGGNLMKGWESYLRKTSIEPLSFRTFRDDYNDFYIERMLSLTSCTSPATSLFLNENSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYU3</accession>
    <name>A0A1J1GYU3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00506000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530288.1">
        <property type="nucleotide sequence ID" value="XM_028673880.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYU3"/>
    <dbReference type="GeneID" id="39733593"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00506000"/>
    <dbReference type="OrthoDB" id="375552at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.250">
        <property type="entry name" value="Flavinator of succinate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005631">
        <property type="entry name" value="SDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036714">
        <property type="entry name" value="SDH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03937">
        <property type="entry name" value="Sdh5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109910">
        <property type="entry name" value="YgfY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="176" mass="21269" checksum="248E5F86F90C9E79" modified="2017-02-15" version="1">MKIYYIHLISFTKLPLCYFTTVQLYKPSKFKDIKKKLYLKKKFFKIFNKKQDSDIKNDTFYNIISEYQKNKIRIYKNNKFNICENFNKSPSLENILFKSTTFGYLELQYILSTFLDFEKNRLKKEDILTLSNFFNLSEKEIYDYLCGNELIPKKYSETEVIKSLLKFINVNHPSLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYW1</accession>
    <name>A0A1J1GYW1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cysteine proteinase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00342100</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529008.1">
        <property type="nucleotide sequence ID" value="XM_028672458.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYW1"/>
    <dbReference type="GeneID" id="39731951"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00342100"/>
    <dbReference type="OMA" id="NGYRKPC"/>
    <dbReference type="OrthoDB" id="190265at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02248">
        <property type="entry name" value="Peptidase_C1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000332">
        <property type="entry name" value="Cathepsin L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000169">
        <property type="entry name" value="Pept_cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025660">
        <property type="entry name" value="Pept_his_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013128">
        <property type="entry name" value="Peptidase_C1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000668">
        <property type="entry name" value="Peptidase_C1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039417">
        <property type="entry name" value="Peptidase_C1A_papain-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013201">
        <property type="entry name" value="Prot_inhib_I29"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12411">
        <property type="entry name" value="CYSTEINE PROTEASE FAMILY C1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08246">
        <property type="entry name" value="Inhibitor_I29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00112">
        <property type="entry name" value="Peptidase_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00705">
        <property type="entry name" value="PAPAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00848">
        <property type="entry name" value="Inhibitor_I29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00645">
        <property type="entry name" value="Pept_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00139">
        <property type="entry name" value="THIOL_PROTEASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00639">
        <property type="entry name" value="THIOL_PROTEASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0865">Zymogen</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="Cathepsin propeptide inhibitor" evidence="12">
        <location>
            <begin position="164"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C1A papain C-terminal" evidence="11">
        <location>
            <begin position="262"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG96203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="483" mass="56076" checksum="034C5A78EF01ED4A" modified="2017-02-15" version="1">MEYHMQYPPNEEIKQEKEVFVEKPLEKKFIKKKKSFLIILSISVFSLIALILIYINKDGNKNDILKGTSNENINDEYIINTLLKSKNGKKFFLSKLEELISSYDKNNVTDDKKESDEYKRNSNDRNVTTFKKKEGNLKVVKKEDFVNLHDVGFLMSNLEVVNAFYLFLKENNKKYTTSNKMEEKFFIFSQNYKKIEEHNKKNTLYKKKINKFGDLTYEEFAKKYLNLKHFDIKKNIDNLSGLSNYEEIIQRYKKENEEFSLASFDWRELGGVTPVKDQQTCGSCWAFSSVGAVESQYAIRRNEHVSLSEQQLVDCSSDNYGCNGGYIPLAFEYMIKDGGLCSAEEYPYVDVTPEMCYRKKCKTKHEIKSFVSIPQDKIKEAIKFLGPISISIAVSEDFSFYDSGIYDGDCAKEVNHAVMLVGYGMEETFNTDLNKNENIFYYIIKNSWGEAWGEKGFMKIETNEEGTQKKCLLAKDAYVALID</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYX1</accession>
    <name>A0A1J1GYX1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sporozoite surface protein 3, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SSP3</name>
        <name evidence="4" type="ORF">PGAL8A_00523700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530462.1">
        <property type="nucleotide sequence ID" value="XM_028674072.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYX1"/>
    <dbReference type="GeneID" id="39733770"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00523700"/>
    <dbReference type="OrthoDB" id="369004at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010884">
        <property type="entry name" value="6_CYS_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07422">
        <property type="entry name" value="s48_45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00970">
        <property type="entry name" value="s48_45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51701">
        <property type="entry name" value="6_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013176092" evidence="2">
        <location>
            <begin position="18"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="384"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="3">
        <location>
            <begin position="21"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="431" mass="50096" checksum="F816CEF3154DD861" modified="2017-02-15" version="1">MYILCFLFFFYFFFCSSVENTGYICDFTSEKYNLGININKSEDVICYHKLSRGDTIGIIIPKYEKGYEDFHIITKCFDEISLEPSGDSRKSIYSIFKKNQIELSETQITFNNDNNTSILKINEVEKPTLFYCIFENRDDNKLLTHRGIVEISVDKNPTYNSPSSTDIILDLFNKLTPNVNVGQNSFYIMGYPGYTLYILAQLLNKPLYFFNDNCPLNFEKIGDIYKYTFPKGNAQNFKFFCPMYYEDNNVQIYIALIIIEFRDVGQSLDDIKKGIINKQMKDDIEKNLNKMLNGVEHDYIGNDQLQGLSIEMNDEKNIDLQLDYPCRDSCNNDKCKDFFDNSSCSSKCGHGYRLMNGYDLNNIAHIVVPCNNGECKIEDEIEPLIIFTYTSMIFFCIIITIFTIMIYFLITNRNKKVADPFVTYDSNLNTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYZ4</accession>
    <name>A0A1J1GYZ4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">U1 small nuclear ribonucleoprotein A, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00503000</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRM U1 A/B'' family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530258.1">
        <property type="nucleotide sequence ID" value="XM_028673846.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYZ4"/>
    <dbReference type="GeneID" id="39733563"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00503000"/>
    <dbReference type="OMA" id="ACKILFV"/>
    <dbReference type="OrthoDB" id="277802at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030532">
        <property type="term" value="C:small nuclear ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12246">
        <property type="entry name" value="RRM1_U1A_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12247">
        <property type="entry name" value="RRM2_U1A_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000039">
        <property type="entry name" value="U1 small nuclear ribonucleoprotein A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000029">
        <property type="entry name" value="U2 small nuclear ribonucleoprotein B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10501">
        <property type="entry name" value="U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="9 13" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="RRM" evidence="12">
        <location>
            <begin position="285"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="12">
        <location>
            <begin position="486"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="148"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="22"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="148"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG97457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="558" mass="65176" checksum="3162B52BE69084EC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ91</accession>
    <name>A0A1J1GZ91_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00512600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530354.1">
        <property type="nucleotide sequence ID" value="XM_028673952.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ91"/>
    <dbReference type="GeneID" id="39733659"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00512600"/>
    <dbReference type="OMA" id="YEVQNIY"/>
    <dbReference type="OrthoDB" id="369725at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012362530" evidence="1">
        <location>
            <begin position="18"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="104" mass="12273" checksum="4BC273881C769E88" modified="2017-02-15" version="1">MKHFIFVFFFLFYLVYAQIPYDILSIYKPLNSQSVKVLPGDKVSIDYKLKDIKDDIGKEYSENSLKKLAEKYYKDVDSTDQNILEELDQLKDLLGEKSLFLTIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZH6</accession>
    <name>A0A1J1GZH6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">subtilisin</fullName>
            <ecNumber evidence="2">3.4.21.62</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00028400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyzes peptide amides.</text>
            <dbReference type="EC" id="3.4.21.62"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.62" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530649.1">
        <property type="nucleotide sequence ID" value="XM_028674280.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZH6"/>
    <dbReference type="GeneID" id="39728807"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00028400"/>
    <dbReference type="OMA" id="YSYCESS"/>
    <dbReference type="OrthoDB" id="387243at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="5">
        <location>
            <begin position="155"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="806"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="810"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="855"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="877"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="907"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="925"/>
            <end position="934"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="934" mass="111325" checksum="F5C25AAAE75A776C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZL0</accession>
    <name>A0A1J1GZL0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytoskeleton associated protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00048100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TBCE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530843.1">
        <property type="nucleotide sequence ID" value="XM_028674496.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZL0"/>
    <dbReference type="GeneID" id="39729006"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00048100"/>
    <dbReference type="OMA" id="DNYLHDY"/>
    <dbReference type="OrthoDB" id="409725at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd17044">
        <property type="entry name" value="Ubl_TBCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.190">
        <property type="entry name" value="CAP Gly-rich-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036859">
        <property type="entry name" value="CAP-Gly_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000938">
        <property type="entry name" value="CAP-Gly_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044079">
        <property type="entry name" value="Ubl_TBCE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01302">
        <property type="entry name" value="CAP_GLY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74924">
        <property type="entry name" value="Cap-Gly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CAP-Gly" evidence="7">
        <location>
            <begin position="79"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG98046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="798" mass="96163" checksum="8E4D1285FEC1092F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZQ5</accession>
    <name>A0A1J1GZQ5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cell cycle associated protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00534500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530568.1">
        <property type="nucleotide sequence ID" value="XM_028674190.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733878"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00534500"/>
    <dbReference type="OMA" id="DDPYINH"/>
    <dbReference type="OrthoDB" id="16281at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051553">
        <property type="entry name" value="Ran_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982:SF1">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13540">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="RCC1" evidence="1">
        <location>
            <begin position="2046"/>
            <end position="2100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="689"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1904"/>
            <end position="1925"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="689"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1904"/>
            <end position="1913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1916"/>
            <end position="1925"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2467" mass="295896" checksum="10E21807587AF8D9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZR0</accession>
    <name>A0A1J1GZR0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RAP protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00037500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530737.1">
        <property type="nucleotide sequence ID" value="XM_028674378.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZR0"/>
    <dbReference type="GeneID" id="39728899"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00037500"/>
    <dbReference type="OMA" id="WKIIPIN"/>
    <dbReference type="OrthoDB" id="360738at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013584">
        <property type="entry name" value="RAP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08373">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00952">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51286">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RAP" evidence="2">
        <location>
            <begin position="920"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="515"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="519"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="992" mass="119539" checksum="A8F1381D863A94D9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZT6</accession>
    <name>A0A1J1GZT6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Gametocyte associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00375600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529336.1">
        <property type="nucleotide sequence ID" value="XM_028672822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZT6"/>
    <dbReference type="GeneID" id="39732286"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00375600"/>
    <dbReference type="OMA" id="DMAFRIS"/>
    <dbReference type="OrthoDB" id="378047at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3030.10">
        <property type="entry name" value="Gametocyte protein Pfg27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015299">
        <property type="entry name" value="Gamete_antigen_PLAspp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036469">
        <property type="entry name" value="Pfg27_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09216">
        <property type="entry name" value="Pfg27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89162">
        <property type="entry name" value="Gametocyte protein Pfg27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="258" mass="30255" checksum="5DF581131BFD56C4" modified="2017-02-15" version="1">MYTYLFFEMKIFRIIYFFCFLYVNLWTTILYDIYLFLILNNDIFHKYNLDIWQKTKRNLAEASRDGLKRKRTHDDSLTDDESLHLSVVCNLEYIALKMSTQMVIDASGDSIDDTVLDMVRINNTVRSLLDYNNITLSEEKIQNMALRISDRFEEMFSSGSFTLDKINNMLKFYMIEAVLSYNLLRSATSQPHEDDRISMLNNVDGIKYEISKRFNHSNVLLSASTINNMALRIRESVQDLLDAVYTTELPLSKNIRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZX0</accession>
    <name>A0A1J1GZX0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ketoreductase (KR) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00060100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530963.1">
        <property type="nucleotide sequence ID" value="XM_028674629.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZX0"/>
    <dbReference type="GeneID" id="39729126"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00060100"/>
    <dbReference type="OMA" id="ICGVFEE"/>
    <dbReference type="OrthoDB" id="37659at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047560">
        <property type="term" value="F:3-dehydrosphinganine reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006666">
        <property type="term" value="P:3-keto-sphinganine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013968">
        <property type="entry name" value="PKS_KR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43550">
        <property type="entry name" value="3-KETODIHYDROSPHINGOSINE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43550:SF3">
        <property type="entry name" value="3-KETODIHYDROSPHINGOSINE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08659">
        <property type="entry name" value="KR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="367"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="Ketoreductase (KR)" evidence="2">
        <location>
            <begin position="70"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="402" mass="47069" checksum="596C25D67BE4CADF" modified="2017-02-15" version="1">MLDYFRKYIYFELLLILFFINYRNPLNVYINIAIIFYLTLLGLIYLIFKFKYTNYKKAQINYNLSDKHICIIGGSEGLGLSLAKRIIKEKPKTLTLMSRNIDKLKEAKKYLLKEIERKSNEEGDNYFGIKINIIKCDISIKESIKEAFDNALTNNSLDIEENEEDYIVSNSTRSRKQKIIKEECHLEEKNYIDVLICNAAYVTTGEYNKLQLYDLIYTINTNIYGNIDIMSKVIINMKKKKSGLILFINTEGVLYPIYGFSYYLMSKSSMWTYTYILDQELKYFNIHIVNAFLPSVDTPGFAQESIKKPDITKKLENLTNTLNSDYVADKVINNVKKGKKFITLEFNGYILSILHSNYRNPESYFDYLIYVSFSSLIVFISSLYKLYIEYVIKKGVQSALYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZZ2</accession>
    <name>A0A1J1GZZ2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00062900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530987.1">
        <property type="nucleotide sequence ID" value="XM_028674657.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZZ2"/>
    <dbReference type="GeneID" id="39729154"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00062900"/>
    <dbReference type="OrthoDB" id="369853at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG98190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="324" mass="38379" checksum="D08B9C5D71A54B8F" modified="2017-02-15" version="1">MKIEKRSDNRSFDSILPIHIDIDQINEENKTCKYISGNINGVIYNKNTNNKLIKIVGGDYNYEIKDNKKIILGNGSKSLVTTTLIGPTQNNLIFSKDIEYVQFNIRIKNMNGNRTEREKIFEEIITKNFEQIFDHSLYKFQQFYFKVQILHECSYILSSIINSIMINCIYNNISLNYVINSINIGIVDKQKYQNFIDDKYSSSDFILEDDDNNNKENKNEYQNIRDKLFYEYKSKYIPKIILDPLNEEIELYCNSAFCFIVAPKFHKVLSNILIKNHLGISRELFLLSESYAYQVSNFLHENIKKNYKLHLNKMETYLNNNYFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H018</accession>
    <name>A0A1J1H018_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00033400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530696.1">
        <property type="nucleotide sequence ID" value="XM_028674333.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H018"/>
    <dbReference type="GeneID" id="39728857"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00033400"/>
    <dbReference type="OMA" id="MQNIDYE"/>
    <dbReference type="OrthoDB" id="354856at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="125" mass="15371" checksum="9BC08513BABC9B58" modified="2017-02-15" version="1">MFYIIKNVVKNIKHFNDVKTILILKENILKEKNLVDEYKFSNSLSHIFFNGTPIFLENNKKENTLLFNKVRNDKKYRKRGFQKRGYWKKMHYFIRKNNMMCYAFKVQNIDYEKIKKLKRGEIYSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0H3</accession>
    <name>A0A1J1H0H3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00436300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529584.1">
        <property type="nucleotide sequence ID" value="XM_028673097.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0H3"/>
    <dbReference type="GeneID" id="39732895"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00436300"/>
    <dbReference type="OMA" id="NTYEINE"/>
    <dbReference type="OrthoDB" id="385054at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="302"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="452"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="304"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="325"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1036" mass="125943" checksum="B96976790414D738" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0I8</accession>
    <name>A0A1J1H0I8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00462200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529845.1">
        <property type="nucleotide sequence ID" value="XM_028673387.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0I8"/>
    <dbReference type="GeneID" id="39733155"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00462200"/>
    <dbReference type="OMA" id="CFDLFFN"/>
    <dbReference type="OrthoDB" id="370906at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="455" mass="54260" checksum="DBEFB49E82EA4227" modified="2017-02-15" version="1">MDKKLKKGILLIRKYAEKYKNVIFKTLKLKSRKTINKKKKKKEKKILKIIEKNNNNTEYKEEKKRKLDNYLINQEKELDFQENYSFFNKFHDRTDNIFYKNENDNVPDSLKLKKTKHNNEEQTFNSINDNFLDSLNSLHFKIKQEIEANNDLLSLKEFSERNNITKVESNTQNDINKQKISQTDEDLKASFKKEENFTEKQLVYPSKKKIKKKKNDSKYMLSSKCEKKINHSSDIELNENYQSIYLGKEKLNLLENKDEEKKNEKIVSSFNMNPKKIIDDTIQKNNEILTEKKKNDLVFGKNKFENINELFQKVFEGNEYNQNNSNEIVKYNNQEKDEDNINVNEYGEKNMTIYHNILNKKEGTYVNEYFKGDINCQDTKIISEENVNCNDNKNNLNHVEKDEYRDNIGDINTPCNQNNLEEIKKYNNVLTPFKEDNSFDFFFNESLGTPSIFQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0Q5</accession>
    <name>A0A1J1H0Q5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nucleolar protein Nop52, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00444200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529664.1">
        <property type="nucleotide sequence ID" value="XM_028673185.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0Q5"/>
    <dbReference type="GeneID" id="39732975"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00444200"/>
    <dbReference type="OMA" id="TIEYIPR"/>
    <dbReference type="OrthoDB" id="2019504at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010301">
        <property type="entry name" value="RRP1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05997">
        <property type="entry name" value="Nop52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="486"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="486"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="508"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="522"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="613" mass="73024" checksum="F71AB625DF53E35B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H168</accession>
    <name>A0A1J1H168_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcription initiation factor IIE, alpha subunit, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00064400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028531002.1">
        <property type="nucleotide sequence ID" value="XM_028674673.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H168"/>
    <dbReference type="GeneID" id="39729169"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00064400"/>
    <dbReference type="OMA" id="FMELQDE"/>
    <dbReference type="OrthoDB" id="361102at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005673">
        <property type="term" value="C:transcription factor TFIIE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039997">
        <property type="entry name" value="TFE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017919">
        <property type="entry name" value="TFIIE/TFIIEa_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002853">
        <property type="entry name" value="TFIIE_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024550">
        <property type="entry name" value="TFIIEa/SarR/Rpc3_HTH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13097:SF7">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13097">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIE, ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02002">
        <property type="entry name" value="TFIIE_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00531">
        <property type="entry name" value="TFIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51344">
        <property type="entry name" value="HTH_TFE_IIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH TFE/IIEalpha-type" evidence="4">
        <location>
            <begin position="9"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="286"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG98205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="388" mass="46245" checksum="4F07F6618852C8DF" modified="2017-02-15" version="1">MDKTKEIFYDKEKKFFLYLMIYISRFFMSDEEIVIFDLFIHNECLYLEKDIINSINMNEHKIRSILSKLLRDKFIIEVQKYKNNEKGSNSQTYYCLNNYIVYVIDFRIKQMENEIQKKKNESDIYICNYCNCTYSQLDAQTLPLDSYDAHFLCFCNNKIELIENDDNNDEKIYNKYTKYLNILKEYIEKLKNYFIPLYTEKFNRSNLNSSNSFLSDNSSDGSVTNNSSEISLTNNSSLISQIHLNESIENGKRKKEEIYTDTCSSVIRKNKKIKICMNVKTKNIIRKNLNDDKIKISNTINDTKEENIINKNKNNDTSENNESIEKSNQNAKNITNEQQTKEPEFPLFFIQKFNKKFTLIDAQKLQQDMSQEEFENFMELQDIYLDKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1I6</accession>
    <name>A0A1J1H1I6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00376800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000097">
        <property type="protein sequence ID" value="CRG97395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530197.1">
        <property type="nucleotide sequence ID" value="XM_028673779.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1I6"/>
    <dbReference type="GeneID" id="39732298"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00376800"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="96" mass="11508" checksum="EF1714D5E2C21982" modified="2017-02-15" version="1">MSYNQINTTTTPGLPLNISLHNELHNITNNKYKSINPYKFLFFIFVVIYLIVKLFSCRLFRCVHRRQRRDNNYDLISIDSGYFENFHEDGQEENVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1L4</accession>
    <name>A0A1J1H1L4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00478400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530008.1">
        <property type="nucleotide sequence ID" value="XM_028673569.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1L4"/>
    <dbReference type="GeneID" id="39733317"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00478400"/>
    <dbReference type="OMA" id="ANENSCI"/>
    <dbReference type="OrthoDB" id="371350at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="234" mass="27981" checksum="EBD171797CC5CF0E" modified="2017-02-15" version="1">MKYYLDFLKKKLTIKSDTNKHSENKSLYIKKEEIDIVKKKLTEKDKIKEDSNLKLIKLANTNNLEFCTNVNFTIENIKCNEIRRFYLNNSNNFVNYDGLKCNILSAVYCDKKNILFYLLVFSFTNIDKYYLELIKIHIKNSKTEESIVKNTEFILVNNNDDIKNENKRTFTNIKIAMKIQENKEISQFANQNSFIQDISLDNIFYIIEYRKWNNYCECFENANYNALNSNYKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2R4</accession>
    <name>A0A1J1H2R4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EIPR1-like beta-propeller domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00535700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat EIPR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530580.1">
        <property type="nucleotide sequence ID" value="XM_028674204.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2R4"/>
    <dbReference type="GeneID" id="39733890"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00535700"/>
    <dbReference type="OrthoDB" id="427795at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059104">
        <property type="entry name" value="Beta-prop_EIPR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040323">
        <property type="entry name" value="EIPR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14205:SF15">
        <property type="entry name" value="EARP AND GARP COMPLEX-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14205">
        <property type="entry name" value="WD-REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23609">
        <property type="entry name" value="Beta-prop_EIPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="EIPR1-like beta-propeller" evidence="5">
        <location>
            <begin position="261"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="308"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="451" mass="53077" checksum="FB794906438FAF5B" modified="2017-02-15" version="1">MYSNKCSKNVYYLPFKSKCLSNVNGKLLSEAYNLHYFLLSSNNPFNDNEVHLIEYNEQDFCVRNVNIFEYKGRIDQIICLDMYEEEERKKKKILLCTSGCNTSDLCNNENNKNEIENSCSLWLGDIETSEEQEKENIEIEEEKDLENMEIEDNLKVEQNDTEKLKHILSDETNQDKKECNEDDKKKENELKTNEINKRITKNKLIKQKKVPLKKIYELKSDQIYKSIKKIAIDDYEKEISKIAVIDKYSYSIFTKNNKDIQFIQSKNVGKQLTYGIFDPHHQDILTVMSDINIYGYDIKSNKQIFSAYTNHKANLSSIDFNSNIPNIVITSSNDGYIKLWDLRFLKNSFLTINIHSHWITSVNFNHFHDELLLTTSTDNTVKLHKIEFRNNLNLQNKDTNYELIKTYKDHEESVYQGKWSKTDAWIFASLSYDGKCVVNSVPNEQKYKILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H322</accession>
    <name>A0A1J1H322_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Histamine-releasing factor, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">TCTP</name>
        <name evidence="5" type="ORF">PGAL8A_00032200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TCTP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530684.1">
        <property type="nucleotide sequence ID" value="XM_028674319.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H322"/>
    <dbReference type="GeneID" id="39728845"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00032200"/>
    <dbReference type="OMA" id="CAMITEG"/>
    <dbReference type="OrthoDB" id="10248936at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.10">
        <property type="entry name" value="Metal Binding Protein, Guanine Nucleotide Exchange Factor, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011323">
        <property type="entry name" value="Mss4/transl-control_tumour"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034737">
        <property type="entry name" value="TCTP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018105">
        <property type="entry name" value="Translational_control_tumour_p"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11991">
        <property type="entry name" value="TRANSLATIONALLY CONTROLLED TUMOR PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11991:SF0">
        <property type="entry name" value="TRANSLATIONALLY-CONTROLLED TUMOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00838">
        <property type="entry name" value="TCTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01653">
        <property type="entry name" value="TCTPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="Mss4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51797">
        <property type="entry name" value="TCTP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TCTP" evidence="4">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="171" mass="20060" checksum="9BA880139213DD42" modified="2017-02-15" version="1">MKVYKDVFTNDEVCSDSYNQEDPFGNPEFRNIAFEVKSNKRIKGNEDYGIADNSEEMQEGMGADVEQVIDIVDSFQLTSTSFSKKEYSAYIKNYMQKVVKYLEEKKPDRVEVFKTQAQPFIKHILTNYNDFELYMGESLDMEAGLIYSYYKGEELTPRFVYISDGLYEEKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H408</accession>
    <name>A0A1J1H408_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00052500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530887.1">
        <property type="nucleotide sequence ID" value="XM_028674546.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H408"/>
    <dbReference type="GeneID" id="39729050"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00052500"/>
    <dbReference type="OMA" id="NADHNMD"/>
    <dbReference type="OrthoDB" id="386880at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="189"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="309"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="533"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="925"/>
            <end position="1108"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="216"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="464"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="309"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="349"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="540"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="932"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="953"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="972"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="989"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1061"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1090"/>
            <end position="1101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG98090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1108" mass="132393" checksum="AC5BC0D10837B709" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H4B7</accession>
    <name>A0A1J1H4B7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00062500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530983.1">
        <property type="nucleotide sequence ID" value="XM_028674652.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729150"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00062500"/>
    <dbReference type="OMA" id="FICLEKC"/>
    <dbReference type="OrthoDB" id="372201at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="332"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="875"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="914"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1446"/>
            <end position="1465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1497"/>
            <end position="1518"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="2139"/>
            <end position="2157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="2178"/>
            <end position="2197"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3536" mass="432792" checksum="CD6A0E7165245E84" modified="2017-02-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2012-05-16" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>H7CDY9</accession>
    <name>H7CDY9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Apicoplast ribosomal protein S2, putative</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="3">Small subunit ribosomal protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rps2</name>
        <name evidence="4" type="synonym">RPS2</name>
        <name evidence="4" type="ORF">PGAL8A_API03900</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <geneLocation type="apicoplast" evidence="3"/>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Mol. Biol. Evol." volume="29" first="2095" last="2099">
            <title>The Plasmodium Apicoplast Genome: Conserved Structure and Close Relationship of P. ovale to Rodent Malaria Parasites.</title>
            <authorList>
                <person name="Arisue N."/>
                <person name="Hashimoto T."/>
                <person name="Mitsui H."/>
                <person name="Palacpac N.M.Q."/>
                <person name="Kaneko A."/>
                <person name="Kawai S."/>
                <person name="Hasegawa M."/>
                <person name="Tanabe K."/>
                <person name="Horii T."/>
            </authorList>
            <dbReference type="PubMed" id="22396524"/>
            <dbReference type="DOI" id="10.1093/molbev/mss082"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">A8</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS2 family.</text>
    </comment>
    <dbReference type="EMBL" id="AB649424">
        <property type="protein sequence ID" value="BAL70759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LN835293">
        <property type="protein sequence ID" value="CRG98249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009325476.1">
        <property type="nucleotide sequence ID" value="NC_031963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="H7CDY9"/>
    <dbReference type="GeneID" id="30315789"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_API03900"/>
    <dbReference type="OrthoDB" id="387575at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Apicoplast API"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005763">
        <property type="term" value="C:mitochondrial small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.610">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00291_B">
        <property type="entry name" value="Ribosomal_uS2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001865">
        <property type="entry name" value="Ribosomal_uS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005706">
        <property type="entry name" value="Ribosomal_uS2_bac/mit/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023591">
        <property type="entry name" value="Ribosomal_uS2_flav_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12534">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S2 PROKARYOTIC AND ORGANELLAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12534:SF0">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00318">
        <property type="entry name" value="Ribosomal_S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52313">
        <property type="entry name" value="Ribosomal protein S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0933">Apicoplast</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0934">Plastid</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAL70759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG98249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="228" mass="27585" checksum="250F560882853B94" modified="2012-05-16" version="1">MFITFKNLLKSNIYIGNNFQNIHFNNYKFIYKIKYNNCILNFTLIALYLYKLYIYIYNIFLLNQKILFINNNNNLMLNFIIKICNLTNNFYIIKWIPGLLTNWSIFKKKIIIYIWLYKLLKNKYLINIISKKCLIKLNIIYNKLNNKFKGIKYMLNIPKYIFLTNFNNDLILNEILKLKLILISFINLSLDSNIINIKILGNYNNYKSLKLIYQIIYTSIIHSKIKNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKQ1</accession>
    <name>A0A1J1GKQ1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cell division control protein 73 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00068000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CDC73 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG92976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525798.1">
        <property type="nucleotide sequence ID" value="XM_028671310.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKQ1"/>
    <dbReference type="GeneID" id="39729205"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00068000"/>
    <dbReference type="OrthoDB" id="2186602at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016593">
        <property type="term" value="C:Cdc73/Paf1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032968">
        <property type="term" value="P:positive regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11990">
        <property type="entry name" value="RNA polymerase II accessory factor, Cdc73 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007852">
        <property type="entry name" value="Cdc73/Parafibromin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031336">
        <property type="entry name" value="CDC73_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038103">
        <property type="entry name" value="CDC73_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12466">
        <property type="entry name" value="CDC73 DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12466:SF8">
        <property type="entry name" value="PARAFIBROMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05179">
        <property type="entry name" value="CDC73_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="Cell division control protein 73 C-terminal" evidence="6">
        <location>
            <begin position="747"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="576"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG92976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="923" mass="110974" checksum="4DE6F21CECA5F276" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL46</accession>
    <name>A0A1J1GL46_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">BIR protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00083800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525956.1">
        <property type="nucleotide sequence ID" value="XM_028670866.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL46"/>
    <dbReference type="GeneID" id="39729362"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00083800"/>
    <dbReference type="OrthoDB" id="6288734at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="231" mass="28268" checksum="A7874148D2F5C68E" modified="2017-02-15" version="1">MNINVFKGKRNYFTAIDRKLREVPYLSRYIILEKFKKKPRYMSECVGTPRRAYGYNTFDKIRYKSTFNPYVKLNKDKKYRLDNWNSRNHEIFDPLKCYVRGSRKSYDIPFSILPNKDELGNFHPPVLSGRYKADIEKQYYMHDLPWVWHKNFYTGTNHFCDNMVVGKKKWYRKEQQKEKMKESMKKINDLVLEYREECKNKKRYNFLENVVNTLGEEIAHKYIRKIKNVYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL69</accession>
    <name>A0A1J1GL69_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Meiotic recombination protein DMC1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00085400</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RecA family. DMC1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525972.1">
        <property type="nucleotide sequence ID" value="XM_028671043.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL69"/>
    <dbReference type="GeneID" id="39729378"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00085400"/>
    <dbReference type="OMA" id="ANPMKPV"/>
    <dbReference type="OrthoDB" id="10251254at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000794">
        <property type="term" value="C:condensed nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070192">
        <property type="term" value="P:chromosome organization involved in meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000730">
        <property type="term" value="P:DNA recombinase assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042148">
        <property type="term" value="P:DNA strand invasion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006312">
        <property type="term" value="P:mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19514">
        <property type="entry name" value="DMC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000080">
        <property type="entry name" value="Meiotic recombination protein DMC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000239">
        <property type="entry name" value="Meiotic recombination protein DMC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011940">
        <property type="entry name" value="Dmc1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016467">
        <property type="entry name" value="DNA_recomb/repair_RecA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010995">
        <property type="entry name" value="DNA_repair_Rad51/TF_NusA_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013632">
        <property type="entry name" value="Rad51_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020587">
        <property type="entry name" value="RecA_monomer-monomer_interface"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003301">
        <property type="entry name" value="PRK04301.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02238">
        <property type="entry name" value="recomb_DMC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22942:SF30">
        <property type="entry name" value="MEIOTIC RECOMBINATION PROTEIN DMC1_LIM15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22942">
        <property type="entry name" value="RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14520">
        <property type="entry name" value="HHH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08423">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005856">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47794">
        <property type="entry name" value="Rad51 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50163">
        <property type="entry name" value="RECA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0469">Meiosis</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecA family profile 1" evidence="10">
        <location>
            <begin position="106"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="RecA family profile 2" evidence="11">
        <location>
            <begin position="284"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG93150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="347" mass="37822" checksum="A0765CAE6C1453C8" modified="2017-02-15" version="1">MSTLPASKSVSKVAIATSIEEDIAKEQQFQEIEKLQDLGINAADINKLKGSGYCTILSLIQSTKKELCNVKGISETKVDKILEVASKIENCSSFITANQLVQKRSKVLKITTGSKVLDQTLGGGIESMSITELFGENRCGKTQICHTLTVTAQLPKNLNGGNGKVCYIDTEGTFRPEKICKIAERYGLNGEAVLDNILYARAFTHEHLYQLLAISAAKMCEEPFALLVVDSIISLFRVDFSGRGELSERQQKLNKTMSILSKLGEQFNIAILITNQVMSDPGATMTFIANPMKPVGGHVIGHASTVRLSLRKGKGDQRVCKVYDAPNLPEVECVFQLSDTGIIDATD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLH6</accession>
    <name>A0A1J1GLH6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Regulator of chromosome condensation, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00092100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526039.1">
        <property type="nucleotide sequence ID" value="XM_028671788.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729445"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00092100"/>
    <dbReference type="OrthoDB" id="10256179at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051709">
        <property type="entry name" value="Ub-ligase/GTPase-reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45622:SF57">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_59, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45622">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13540">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="441"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1354" mass="159478" checksum="1E41EABCC030DB25" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLJ9</accession>
    <name>A0A1J1GLJ9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleoside transporter 4, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">NT4</name>
        <name evidence="2" type="ORF">PGAL8A_00099200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526108.1">
        <property type="nucleotide sequence ID" value="XM_028672555.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLJ9"/>
    <dbReference type="GeneID" id="39729516"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00099200"/>
    <dbReference type="OMA" id="LSYGRIC"/>
    <dbReference type="OrthoDB" id="392444at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="288"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="323"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="354"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="387"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="427"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="451" mass="51921" checksum="788262B7F9BADC7A" modified="2017-02-15" version="1">MLKGEETQIKLIFFFLGILLSLPSNIIINVSFLINNIYNEEISITILGFISGFMIISSLIQLTFEFTSFKSIIICNFLNAANLFIFLILICLCNASKHYIYIISAFIGFFIGFLYSANTKYSLLFGMRINGYLVSGISFCALFFFIINLLMSYLTIEDGNVKSYYNAITLSIGTVVVLKVLIIIYIIFMHLRSPYFLEQKERIESRKTKEINIDSELNTFNEVENGENNLSKGVSSYDKNSNDNDDKKIEVTVKDNISKISKINKKLKFPKKIFNCNNIIDGARLIKYYYLCLIPISFNIFITFVIYPHIIPNKLKKGVYYKYLFMFLFQCSDLIFSFLVTVYLNLFSFFKQQYVTILCICRILLLVLAYKIKNLQEDSFLYTNEFIAFVIFLVGSTNGSLINLSYGRICDCFKHSDQKEKNIAVSSSFCALTFLISFALSPWFCGLIIDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLL8</accession>
    <name>A0A1J1GLL8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribosome-recycling factor, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RRF2</name>
        <name evidence="5" type="ORF">PGAL8A_00094000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RRF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526058.1">
        <property type="nucleotide sequence ID" value="XM_028671999.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLL8"/>
    <dbReference type="GeneID" id="39729464"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00094000"/>
    <dbReference type="OrthoDB" id="386993at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.20">
        <property type="entry name" value="Ribosome-recycling factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002661">
        <property type="entry name" value="Ribosome_recyc_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023584">
        <property type="entry name" value="Ribosome_recyc_fac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036191">
        <property type="entry name" value="RRF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982:SF3">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME RECYCLING FACTOR PSEUDO 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982">
        <property type="entry name" value="RIBOSOME RECYCLING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01765">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55194">
        <property type="entry name" value="Ribosome recycling factor, RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosome recycling factor" evidence="4">
        <location>
            <begin position="100"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="189"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="260" mass="31129" checksum="F347A459C37BE158" modified="2017-02-15" version="1">MKIPRSYRPFYQSLYFTKWKFKFCSVYNFFIQQMDFGSKKQKEKIGKETKKIRKILKISNMNNDEIESINLNEKQKITIEKNKIDYKVYDFKLQEIIKNFENKIKKIFDNSLSIETFNNISVIKDKKNFKLSDLAQVVIKSSSLIYFYPYMINDIQKIIHNLKIKDNSWNPIASNDNQSILLQIPPLTNEAKLKKKKEAKDLLEKIKGDIRNIRHKIRDDIIKNIEGEEWKVVEKNKLDNYIKTKIKNIENIYENSIKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLQ2</accession>
    <name>A0A1J1GLQ2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">1-cys peroxiredoxin, putative</fullName>
            <ecNumber evidence="9">1.11.1.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">AOP</name>
        <name evidence="9" type="ORF">PGAL8A_00095700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peroxiredoxin family. Prx5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.15" evidence="9"/>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526073.1">
        <property type="nucleotide sequence ID" value="XM_028672165.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLQ2"/>
    <dbReference type="GeneID" id="39729481"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00095700"/>
    <dbReference type="OrthoDB" id="1882547at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03013">
        <property type="entry name" value="PRX5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037944">
        <property type="entry name" value="PRX5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10430">
        <property type="entry name" value="PEROXIREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10430:SF16">
        <property type="entry name" value="PEROXIREDOXIN-5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="4 6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 6 9" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="6" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012610876" evidence="7">
        <location>
            <begin position="19"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="Redoxin" evidence="8">
        <location>
            <begin position="75"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="5">
        <location>
            <position position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR637944-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="237" mass="28082" checksum="7B234E29B672C086" modified="2017-02-15" version="1">MTKIILIFFHILVNFSFCFKNLLYNQSLNIVAKRCPNRCRSSQKLYESKNIDLANDIKENDFIPNVKVMIDVKNINNIPETNGENNFKVIDTHELFKNKKILLISLPGAFTPTCTSKMIPQYEYEYEFFIKEKKFDDIYCITNNDIFVLKSWFKNMNIKNIKYISDGNSSFTESMNMLVDKSNFFMGMRPWRFVAIIEHNILVKMFQEKDKQHNIQSDPYEISSVDNVKQFLMNNEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLS5</accession>
    <name>A0A1J1GLS5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UDP-N-acetylglucosamine transferase subunit ALG13</fullName>
            <ecNumber evidence="3">2.4.1.141</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00108900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.141" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526206.1">
        <property type="nucleotide sequence ID" value="XM_028673644.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLS5"/>
    <dbReference type="GeneID" id="39729615"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00108900"/>
    <dbReference type="OMA" id="HENHQAE"/>
    <dbReference type="OrthoDB" id="20273at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004577">
        <property type="term" value="F:N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039042">
        <property type="entry name" value="Alg13-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007235">
        <property type="entry name" value="Glyco_trans_28_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12867">
        <property type="entry name" value="GLYCOSYL TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12867:SF6">
        <property type="entry name" value="N-ACETYLGLUCOSAMINYLDIPHOSPHODOLICHOL N-ACETYLGLUCOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04101">
        <property type="entry name" value="Glyco_tran_28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyl transferase family 28 C-terminal" evidence="8">
        <location>
            <begin position="3"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="169" mass="20039" checksum="E5D436F24AE5F8BE" modified="2017-02-15" version="1">MYLFVTVGSTKFDELIKFIDNEEFHFFLKKKGFAYMTIQIGNGSYIPKLIYKNKEDNNLLKKVDYFTFKSSLDYFYEKCDLVLSHAGAGTTIECLRKRKKILIVVNTNLMNNHQMEFAEYMYSCNYLEICKNLNTLKDNIHTCLNKKYKIFPKPNIQNFLQDINNLMNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLW9</accession>
    <name>A0A1J1GLW9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cleavage and polyadenylation specificity factor subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Cleavage and polyadenylation specificity factor 100 kDa subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00112000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526236.1">
        <property type="nucleotide sequence ID" value="XM_028673977.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729645"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00112000"/>
    <dbReference type="OrthoDB" id="64353at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006398">
        <property type="term" value="P:mRNA 3'-end processing by stem-loop binding and cleavage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022712">
        <property type="entry name" value="Beta_Casp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027075">
        <property type="entry name" value="CPSF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45922">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45922:SF1">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16661">
        <property type="entry name" value="Lactamase_B_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01027">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Beta-Casp" evidence="4">
        <location>
            <begin position="312"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="654"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="467"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="654"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="688"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="711"/>
            <end position="805"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU365006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1440" mass="171664" checksum="0B0AB76EC36775DB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLY7</accession>
    <name>A0A1J1GLY7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PCIF1 WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00115400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526270.1">
        <property type="nucleotide sequence ID" value="XM_028674354.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729679"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00115400"/>
    <dbReference type="OMA" id="RYCFFFY"/>
    <dbReference type="OrthoDB" id="193787at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016422">
        <property type="term" value="F:mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099122">
        <property type="term" value="F:RNA polymerase II C-terminal domain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039881">
        <property type="entry name" value="PCIF1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022035">
        <property type="entry name" value="PCIF1_WW"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21727:SF0">
        <property type="entry name" value="MRNA (2'-O-METHYLADENOSINE-N(6)-)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21727">
        <property type="entry name" value="PHOSPHORYLATED CTD INTERACTING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12237">
        <property type="entry name" value="PCIF1_WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="402"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="785"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1035"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1058"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1115"/>
            <end position="1133"/>
        </location>
    </feature>
    <feature type="domain" description="PCIF1 WW" evidence="3">
        <location>
            <begin position="1112"/>
            <end position="1266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="462"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="468"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1314" mass="161112" checksum="B2B89F7153A5D946" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMD2</accession>
    <name>A0A1J1GMD2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="6">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">UBE4B</name>
        <name evidence="13" type="ORF">PGAL8A_00119700</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ubiquitin conjugation factor E4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526313.1">
        <property type="nucleotide sequence ID" value="XM_028674709.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMD2"/>
    <dbReference type="GeneID" id="39729722"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00119700"/>
    <dbReference type="OrthoDB" id="20295at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000151">
        <property type="term" value="C:ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034450">
        <property type="term" value="F:ubiquitin-ubiquitin ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000055">
        <property type="entry name" value="Ubiquitin conjugation factor e4 a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019474">
        <property type="entry name" value="Ub_conjug_fac_E4_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045132">
        <property type="entry name" value="UBE4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13931:SF2">
        <property type="entry name" value="UBIQUITIN CONJUGATION FACTOR E4 B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13931">
        <property type="entry name" value="UBIQUITINATION FACTOR E4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04564">
        <property type="entry name" value="U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10408">
        <property type="entry name" value="Ufd2P_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="U-box" evidence="12">
        <location>
            <begin position="1138"/>
            <end position="1212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="238"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="943"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1212"/>
            <end position="1263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="240"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="945"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1212"/>
            <end position="1221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1230"/>
            <end position="1263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG93491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1263" mass="148492" checksum="1F22923BB8BE3E77" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMD7</accession>
    <name>A0A1J1GMD7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">JmjC domain containing protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00131300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526430.1">
        <property type="nucleotide sequence ID" value="XM_028674839.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMD7"/>
    <dbReference type="GeneID" id="39729838"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00131300"/>
    <dbReference type="OrthoDB" id="263283at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461:SF105">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1-ALPHA INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="2">
        <location>
            <begin position="260"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="550"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="692" mass="83255" checksum="8C736200DC5DDA87" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GME0</accession>
    <name>A0A1J1GME0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Lipoprotein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00120600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526321.1">
        <property type="nucleotide sequence ID" value="XM_028674718.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GME0"/>
    <dbReference type="GeneID" id="39729731"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00120600"/>
    <dbReference type="OrthoDB" id="371412at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009618925" description="Lipoprotein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="206" mass="24160" checksum="52C51A0D9DAEB698" modified="2017-02-15" version="1">MKYPFFFVLLFIYLFSYFCNCEKVKKNKNLRNLLKSLTNRVDTDDGKNEYSRLTQSPKIEMKLSKANFKTTLQNILIQSYSENVKELISKTNYEIQKEKSLLDEINNSNFNLNKIADILSGSTNIKRSNKLRNKYSHYLGDNDLGLIFLPIYKTFKSNSSHFNNNLYSSLLPHELLEKGYLSNEQILRNSQKKLLFPERGDITLEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMQ1</accession>
    <name>A0A1J1GMQ1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">SNARE associated Golgi protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00139500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TMEM41 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526511.1">
        <property type="nucleotide sequence ID" value="XM_028674929.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMQ1"/>
    <dbReference type="GeneID" id="39729919"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00139500"/>
    <dbReference type="OMA" id="CIKIPRD"/>
    <dbReference type="OrthoDB" id="3364966at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045014">
        <property type="entry name" value="TM41A/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="VTT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43220:SF18">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 41B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="VTT_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="220"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="VTT" evidence="7">
        <location>
            <begin position="124"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="283" mass="33294" checksum="39DF2DA079BD6EBC" modified="2017-02-15" version="1">MKKEKKKFTKYESISISKKKNKKVKLHLFYLSVIFFFFILVIGLYIYLMPGLNVESKNRLKILIPKSFKDLKYLSNKEKVKILYDSLILYKNEHGFVLLILLSLFYIFYQSFPLFLWWITGTASIITILIGAFYNYLFSIFYCSILSTISPLIAYVIFKYYGKTVIEHFFKKSLIKFNVQIKKRVKNKFDLFFYIAILRLTPIFPNALINILGASLSLPLLPFLLATYFGLLPNTVILVSVGQAINRLSSVDMKQQFYVPLIFIILLLFFQKLIRNKYKEISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMY9</accession>
    <name>A0A1J1GMY9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00133400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526451.1">
        <property type="nucleotide sequence ID" value="XM_028674862.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMY9"/>
    <dbReference type="GeneID" id="39729859"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00133400"/>
    <dbReference type="OMA" id="TTYNEWK"/>
    <dbReference type="OrthoDB" id="371212at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="47"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="93" mass="10662" checksum="BBD7E7D786492205" modified="2017-02-15" version="1">MDKLKNLLFVKNGNFSSAQIKILAFTSISMLILMVTGDGLQTPLGYIKNVKREMKREEEEKESLEKKLLRELGVTTYQEWKKAGIIPSDDKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN01</accession>
    <name>A0A1J1GN01_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">16S rRNA (uracil(1498)-N(3))-methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.193</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00151000</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>uridine(1498) in 16S rRNA + S-adenosyl-L-methionine = N(3)-methyluridine(1498) in 16S rRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:42920"/>
            <dbReference type="Rhea" id="RHEA-COMP:10283"/>
            <dbReference type="Rhea" id="RHEA-COMP:10284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74502"/>
            <dbReference type="EC" id="2.1.1.193"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNA methyltransferase RsmE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.193" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526623.1">
        <property type="nucleotide sequence ID" value="XM_028675053.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN01"/>
    <dbReference type="GeneID" id="39730034"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00151000"/>
    <dbReference type="OMA" id="EQAMCTQ"/>
    <dbReference type="OrthoDB" id="2021042at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070042">
        <property type="term" value="F:rRNA (uridine-N3-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18084">
        <property type="entry name" value="RsmE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006700">
        <property type="entry name" value="RsmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046886">
        <property type="entry name" value="RsmE_MTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00046">
        <property type="entry name" value="RsmE family RNA methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30027:SF3">
        <property type="entry name" value="16S RRNA (URACIL(1498)-N(3))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30027">
        <property type="entry name" value="RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04452">
        <property type="entry name" value="Methyltrans_RNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 12" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribosomal RNA small subunit methyltransferase E methyltransferase" evidence="11">
        <location>
            <begin position="81"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG93801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="430" mass="50633" checksum="55D64B076D386A7E" modified="2017-02-15" version="1">MNLILISSKCIYEINNEFFFRTDDRQTNHLKSILKVQLNQHVKVGVINKGKGEGIIIEENKNYYVIKLLSPIHLEKPESRFIPIDVVICIPRPKILNKMLQQLSSVGVKKIIIVFSEYSNKSYESSKIFRNEEIKYALQLGLEQAMCTQFPETYIHYSFNSFFMNIQKYADDNTIKLCAHTDIKTNTTSNEFSILNKEEGKILLMLGCERGFSDLEIYLIKKLGFNFLYLTERILKCETAILIIIGQLLLLTENTYLRPNGKKMRRYSKDRNGYIEKNIMKSKNKEEIIENNYNFQDKTEIIHEIKDILVNETFSSEQLKTYISNFIKEHESMKDFENIFSSNEDNVLKQKTNIIDEILKNISSFNKNDENNFENIYLSLLLKKIKYKNRFCLSYNDVKNNVDDDGVFIYRTQRYITKKKKNLLNDLHST</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN18</accession>
    <name>A0A1J1GN18_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">6-pyruvoyltetrahydropterin synthase</fullName>
            <ecNumber evidence="4">4.2.3.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00156500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; tetrahydrobiopterin biosynthesis; tetrahydrobiopterin from 7,8-dihydroneopterin triphosphate: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PTPS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.12" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526678.1">
        <property type="nucleotide sequence ID" value="XM_028675115.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN18"/>
    <dbReference type="GeneID" id="39730090"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00156500"/>
    <dbReference type="OMA" id="CAHFIAF"/>
    <dbReference type="OrthoDB" id="14045at2759"/>
    <dbReference type="UniPathway" id="UPA00849">
        <property type="reaction ID" value="UER00819"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003874">
        <property type="term" value="F:6-pyruvoyltetrahydropterin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.10">
        <property type="entry name" value="6-pyruvoyl tetrahydropterin synthase/QueD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007115">
        <property type="entry name" value="6-PTP_synth/QueD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038418">
        <property type="entry name" value="6-PTP_synth/QueD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12589:SF7">
        <property type="entry name" value="6-PYRUVOYL TETRAHYDROBIOPTERIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12589">
        <property type="entry name" value="PYRUVOYL TETRAHYDROBIOPTERIN SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01242">
        <property type="entry name" value="PTPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55620">
        <property type="entry name" value="Tetrahydrobiopterin biosynthesis enzymes-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0783">Tetrahydrobiopterin biosynthesis</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="172" mass="19937" checksum="80921AB8D8AD5167" modified="2017-02-15" version="1">MDKKLINLENVVSEVLVESPSFSFNCAHFIAYKGFKEKLHGHNYKVSLKMKGSIQNDGYVIDFSILKDVIKKICKELDHRFILPIYSDVLKIEKVNNNIKITCEDNSEYSFPESDCVEIPIKHSSSEEIGNYIIERVIEEIDLSFLKSRKINYIEMCVSESPTQKAILYKYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN30</accession>
    <name>A0A1J1GN30_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">dAMP1 SANT/Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00157100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526684.1">
        <property type="nucleotide sequence ID" value="XM_028675121.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN30"/>
    <dbReference type="GeneID" id="39730096"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00157100"/>
    <dbReference type="OMA" id="CEKYECH"/>
    <dbReference type="OrthoDB" id="19740at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000812">
        <property type="term" value="C:Swr1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032563">
        <property type="entry name" value="DAMP1_SANT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027109">
        <property type="entry name" value="Swc4/Dmap1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12855:SF10">
        <property type="entry name" value="DNA METHYLTRANSFERASE 1-ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12855">
        <property type="entry name" value="DNA METHYLTRANSFERASE 1-ASSOCIATED PROTEIN 1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16282">
        <property type="entry name" value="SANT_DAMP1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="DAMP1 SANT/Myb-like" evidence="7">
        <location>
            <begin position="99"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="347"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="382" mass="46484" checksum="118F56A338640EDC" modified="2017-02-15" version="1">MSHIYDMLGINVEKIKSKKKQKEKKSKKELNFLKENDNLFSLPTSSKIINFNNKNVSIWRLIKFRNKCRYDDLILRKWKKIGYKDDKKLFNENNVEDDYSFERFNKKISVVKYNDEFYNREIKNMNMKWTKEETDYLFDLCEKYECHFIIIYDVYDNKYKRTIEELKDRFYSVSKKIIEDTYDQKIKLEESKKIKNNNDILKLKEGKAKHPLIKFTYNMEADIERKNLLHKTYIVSKKDIMLEETTMENIKKFENKIKHELKKASDMKKLKKKFELTNDEIVPINKIPEDDKEERNVYSARYYFQKLKIDVSYFDKLDAYLKDNNIEKPTIYTESICFLYGTDVAILLNLRKKIEKLKQEKEFWNNQVNNLEEGYLKSKNKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNA0</accession>
    <name>A0A1J1GNA0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00166100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526774.1">
        <property type="nucleotide sequence ID" value="XM_028675220.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730187"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00166100"/>
    <dbReference type="OMA" id="DKNMITT"/>
    <dbReference type="OrthoDB" id="4744100at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="987"/>
            <end position="1162"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="53"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1554"/>
            <end position="1611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="997"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1016"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1084"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1143"/>
            <end position="1162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1863" mass="217379" checksum="27DEAF4A6C3D5AB6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNR8</accession>
    <name>A0A1J1GNR8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mitochondrial carrier protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00175200</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526866.1">
        <property type="nucleotide sequence ID" value="XM_028670078.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNR8"/>
    <dbReference type="GeneID" id="39730279"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00175200"/>
    <dbReference type="OMA" id="NTFHCIK"/>
    <dbReference type="OrthoDB" id="270584at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="388"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="146"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="279"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="387"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="480" mass="56485" checksum="26CF0F78AFC47173" modified="2017-02-15" version="1">MEAYNKNEEEKKEIKNKNKILICGLISGILTKTMFAPFDRIKLFYQIQPMFYHYNTKKKKFILKNTKESTNNNILLNGVDNKNFSKTSEIKKFISNKNIVFHNFKNSLKEIIRTNKKKEKKIYMTNKTSQIYKNYNNSINSHKTFKKILFNYKNNLYLNNLSKNYRFLNSYNVKNMLQNKFSYLTGRKVNNQTFKYKNIIQSFIYIIKEEGILGLWKGNLINTIRGGLVYSSKFGTNDIIKESYKRKKKKNNETLNEYDIKLENSNNYTKNTVEKKKKINYYESLTAGYASGVIQKTVSYPLDLLSIRMALGINEKYLRSNLQYKRKSIFKIIKEINTNEGFSGFFKGFFPTLLTGVPYVTLQMLFFDFYKNIFQNYFSHKSNSLSSIAFYSSISGSLSNLTSLIIVFPGDTVRKRMMNNGIDNKNYIYKNTFHCIKNIYCCEGFKNFYYGLFPSMLKAVPSGAIQFMTYEILKYMLTQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP68</accession>
    <name>A0A1J1GP68_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Inner membrane complex protein 1c, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">IMC1c</name>
        <name evidence="1" type="ORF">PGAL8A_00379800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526915.1">
        <property type="nucleotide sequence ID" value="XM_028670132.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP68"/>
    <dbReference type="GeneID" id="39732328"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00379800"/>
    <dbReference type="OMA" id="YQKADNI"/>
    <dbReference type="OrthoDB" id="448535at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022086">
        <property type="entry name" value="IMCp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12314">
        <property type="entry name" value="IMCp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="282" mass="32957" checksum="9E773E6B858497FF" modified="2017-02-15" version="1">MEGTNKNLNAYQKADNIEPKETSTVDRKWVALTAYQPVDVVTKTVEVPVIKTVEKIVPRTILQEKIVHVPKSVTHVVEKIVEVPEVKYIEKIVEVPHIHYKNKYVPKIEVVEKIIERQKIIEKWHDKIVEVPQIKEVVRFKQIEDAEEIIKYIPKNSGNIDWEAEYRKYMQRKELAGYNVNNTATYQQKINSYNDYNENAYTQNAYDRTYEYMNNQTSLNEPTDYSREAYSQGNLYNQYSRVNYEQEKSIPRSNFDLSGSMQIKRMPSEDTKPVGCCAGACS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPH0</accession>
    <name>A0A1J1GPH0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00410800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527222.1">
        <property type="nucleotide sequence ID" value="XM_028670473.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPH0"/>
    <dbReference type="GeneID" id="39732638"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00410800"/>
    <dbReference type="OMA" id="RNRINID"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="433"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="495"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="433"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="454"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="495"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="508"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="556"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="571" mass="69580" checksum="98BAB18E8EDBA731" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPI1</accession>
    <name>A0A1J1GPI1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00405000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527167.1">
        <property type="nucleotide sequence ID" value="XM_028670412.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732580"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00405000"/>
    <dbReference type="OMA" id="VIVPFCE"/>
    <dbReference type="OrthoDB" id="387391at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="569"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1164"/>
            <end position="1203"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="630"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="569"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1165"/>
            <end position="1200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1593" mass="191506" checksum="D9E392E9112ED489" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPL4</accession>
    <name>A0A1J1GPL4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">mRNA 5'-phosphatase</fullName>
            <ecNumber evidence="7">3.6.1.74</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">Prt1</name>
        <name evidence="11" type="ORF">PGAL8A_00394200</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a 5'-end triphospho-ribonucleoside in mRNA + H2O = a 5'-end diphospho-ribonucleoside in mRNA + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:67004"/>
            <dbReference type="Rhea" id="RHEA-COMP:17164"/>
            <dbReference type="Rhea" id="RHEA-COMP:17165"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:167616"/>
            <dbReference type="ChEBI" id="CHEBI:167618"/>
            <dbReference type="EC" id="3.6.1.74"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:67005"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fungal TPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.74" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527059.1">
        <property type="nucleotide sequence ID" value="XM_028670292.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPL4"/>
    <dbReference type="GeneID" id="39732472"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00394200"/>
    <dbReference type="OrthoDB" id="272147at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140818">
        <property type="term" value="F:mRNA 5'-triphosphate monophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004651">
        <property type="term" value="F:polynucleotide 5'-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07470">
        <property type="entry name" value="CYTH-like_mRNA_RTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.100.10">
        <property type="entry name" value="mRNA triphosphatase Cet1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040343">
        <property type="entry name" value="Cet1/Ctl1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033469">
        <property type="entry name" value="CYTH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004206">
        <property type="entry name" value="mRNA_triPase_Cet1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037009">
        <property type="entry name" value="mRNA_triPase_Cet1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28118:SF1">
        <property type="entry name" value="POLYNUCLEOTIDE 5'-TRIPHOSPHATASE CTL1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28118">
        <property type="entry name" value="POLYNUCLEOTIDE 5'-TRIPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02940">
        <property type="entry name" value="mRNA_triPase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55154">
        <property type="entry name" value="CYTH-like phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="mRNA triphosphatase Cet1-like" evidence="10">
        <location>
            <begin position="37"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="mRNA triphosphatase Cet1-like" evidence="10">
        <location>
            <begin position="220"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="444"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="444"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="466"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="479"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="494"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG94238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="524" mass="61860" checksum="D2FCFB41796C8A48" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPM5</accession>
    <name>A0A1J1GPM5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00184900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000024">
        <property type="protein sequence ID" value="CRG94457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527278.1">
        <property type="nucleotide sequence ID" value="XM_028670536.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPM5"/>
    <dbReference type="GeneID" id="39730376"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00184900"/>
    <dbReference type="OMA" id="FISHTYK"/>
    <dbReference type="OrthoDB" id="365638at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="163" mass="19672" checksum="78E2C69B456DD98B" modified="2017-02-15" version="1">MNYNFNSLKKSLNFKVNNVFFYYRCKVRNTKENFFNKITYSTKNNEYNNSLNINTTEKNKNEKNKIFFSNTKYKAVNSQPKRNLSVFGYNRGKLFVSIKKDFTSFVVNSLIIFVFLYSVYTLAPNETISQRRKRIIRERLMKEYEISEKDLEMIEDFDEILEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPP8</accession>
    <name>A0A1J1GPP8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00187700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000026">
        <property type="protein sequence ID" value="CRG94482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527300.1">
        <property type="nucleotide sequence ID" value="XM_028670560.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPP8"/>
    <dbReference type="GeneID" id="39730404"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00187700"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="346" mass="41649" checksum="47257535142BDD6D" modified="2017-02-15" version="1">MKSITLYLKITTFFLLIWMYQCFFNCDSYKTLIDKNIPQAKNELKNERVLTEGDISGIKRTYVKECIEKCPLYNKKNKCKDPDKYKDPSDYWYMVVIPKMWDRFNQETSEMDPKLKKKKWNVEWHKISTSKVKDLHLMSRRRDITYEEKKRRTDNVLKELDSKFEIFLCECNKEMRDNKTESKSKKEMRENKTESESKKKMRDNKAESESKKEMRDNKTESESDKEMRDYKTESESKKEMKDNKTESESDKVMKDNKTESESDKEMKDNKTESESDKEKKDNKTESESKKEMRENKTESESRKEQGSNEIKNYKLKIWKLLIILIILRRININGLTENIGLVMHKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPQ2</accession>
    <name>A0A1J1GPQ2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Early transcribed membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00180700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527239.1">
        <property type="nucleotide sequence ID" value="XM_028670492.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPQ2"/>
    <dbReference type="GeneID" id="39730334"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00180700"/>
    <dbReference type="OMA" id="CHCDNEN"/>
    <dbReference type="OrthoDB" id="374974at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006389">
        <property type="entry name" value="Early_transc_mb_plasmodium"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01495">
        <property type="entry name" value="ETRAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09716">
        <property type="entry name" value="ETRAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012407671" description="Early transcribed membrane protein" evidence="3">
        <location>
            <begin position="25"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="63"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="116" mass="12791" checksum="DCDFA2B81610FD8D" modified="2017-02-15" version="1">MKFSKVLFIFSVFLAVKYFNPCHCDNENAPSEQIIQVPSSALDEASLAKVDLDIEKKKRNEKLLLISSIATGLAVLIASAVGLGIYTKKRGESEEEEPAEKNSNEETKNSEQGDEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPY8</accession>
    <name>A0A1J1GPY8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA/RNA-binding protein Alba-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00406800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527185.1">
        <property type="nucleotide sequence ID" value="XM_028670432.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPY8"/>
    <dbReference type="GeneID" id="39732598"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00406800"/>
    <dbReference type="OMA" id="TCKVTID"/>
    <dbReference type="OrthoDB" id="372290at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="202" mass="23933" checksum="F08454FD3B06CF8B" modified="2017-02-15" version="1">MFNDLNKKKKKKKKNEITIETIQKENSPILKKKNIDIYITSNKSINIYYERILKILNNSKEVDNIIEGNNKINNLLVSNNEVHIYAVGTNIIKASYLVQDLIKYYYLLLKNIQDSSKKNIKKKIDIYSFIDIKVNSKTLIMNDNVILNKFLIKEEFLSDNYDDLINFSKQSYNQNFHKYIEKNKERRLTNVIISLKKKNVES</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ78</accession>
    <name>A0A1J1GQ78_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WD repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00181400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527243.1">
        <property type="nucleotide sequence ID" value="XM_028670496.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ78"/>
    <dbReference type="GeneID" id="39730341"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00181400"/>
    <dbReference type="OMA" id="NDLPVMW"/>
    <dbReference type="OrthoDB" id="18388at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037379">
        <property type="entry name" value="WDR74/Nsa1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16038">
        <property type="entry name" value="NOP SEVEN ASSOCIATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16038:SF4">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 74"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="387"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="478"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="759" mass="90746" checksum="D3F17B5D4CD4F05F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQR9</accession>
    <name>A0A1J1GQR9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Thioredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00216500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the thioredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527583.1">
        <property type="nucleotide sequence ID" value="XM_028670874.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQR9"/>
    <dbReference type="GeneID" id="39730692"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00216500"/>
    <dbReference type="OMA" id="HIHYVTD"/>
    <dbReference type="OrthoDB" id="2121326at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000104">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01068">
        <property type="entry name" value="thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46115">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000077">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4 7" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Thioredoxin" evidence="8">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="30"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="33"/>
        </location>
    </feature>
    <feature type="site" description="Deprotonates C-terminal active site Cys" evidence="6">
        <location>
            <position position="24"/>
        </location>
    </feature>
    <feature type="site" description="Contributes to redox potential value" evidence="6">
        <location>
            <position position="31"/>
        </location>
    </feature>
    <feature type="site" description="Contributes to redox potential value" evidence="6">
        <location>
            <position position="32"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="7">
        <location>
            <begin position="30"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000077-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000077-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="104" mass="11765" checksum="4ED65EC68AEB0100" modified="2017-02-15" version="1">MVKIISSQADFEDIISQNDVVIVDFFAEWCGPCKRIAPFYEECSEKYKNIVFIKVDVDEASEVTEKENITSMPTFKVYKKGVSVETLLGANDTALKQLIEKYAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQS6</accession>
    <name>A0A1J1GQS6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NEDD8-activating enzyme E1 catalytic subunit</fullName>
            <ecNumber evidence="4">6.2.1.64</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00109900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 4">
            <text>ATP + [NEDD8 protein] + [E1 NEDD8-activating enzyme]-L-cysteine = AMP + diphosphate + [E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine.</text>
            <dbReference type="EC" id="6.2.1.64"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; protein neddylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.64" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526216.1">
        <property type="nucleotide sequence ID" value="XM_028673755.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQS6"/>
    <dbReference type="GeneID" id="39729625"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00109900"/>
    <dbReference type="OMA" id="PYLENYM"/>
    <dbReference type="OrthoDB" id="10255449at2759"/>
    <dbReference type="UniPathway" id="UPA00885"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019781">
        <property type="term" value="F:NEDD8 activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045116">
        <property type="term" value="P:protein neddylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.520">
        <property type="entry name" value="Ubiquitin activating enzymes (Uba3). Chain: B, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023318">
        <property type="entry name" value="Ub_act_enz_dom_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF6">
        <property type="entry name" value="NEDD8-ACTIVATING ENZYME E1 CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="5">
        <location>
            <begin position="6"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU368009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="382" mass="44756" checksum="5E8E97B7F6C79506" modified="2017-02-15" version="1">MIYEFEKLNVLVVGCGGLGNEVIKNLIYINIKNITIVDYDFVEISNLQRQLFFTPNDIGNFKVNVINRIIKDKYKDVNIRSYIKKIELFDLGFFEDFDFIIGCLDNIDSRIYLNNLIFNLKKDIIYIDGGVEGFKGSIKIIDRKNEFACFNCTIENYSNYSFPICSIINKPKTPEECILYVMNVSFKDIKKEKLDKDNENHIKWIYEESKKRAQLFHINNLSYSLTEKVVKNSIPTTISTLMIISSLMITELFNIITFRNRENNYSDILYVGDNGIYMYYYKIYKSPNCMICNKKEIKLTFNKIDKLNKLVDFIKTNYNSKNINISSDSSILFISSKYLRKNYEQKLNSTFQQLIDKGEITIGNSLNIQTDKNNFILFLNLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQU8</accession>
    <name>A0A1J1GQU8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Translation initiation factor IF-1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">IF1</name>
        <name evidence="10" type="ORF">PGAL8A_00228400</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IF-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527702.1">
        <property type="nucleotide sequence ID" value="XM_028671006.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQU8"/>
    <dbReference type="GeneID" id="39730811"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00228400"/>
    <dbReference type="OMA" id="FEQRRGK"/>
    <dbReference type="OrthoDB" id="1714886at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006196">
        <property type="entry name" value="RNA-binding_domain_S1_IF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004368">
        <property type="entry name" value="TIF_IF1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00008">
        <property type="entry name" value="infA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33370">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33370:SF1">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR IF-1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01176">
        <property type="entry name" value="eIF-1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50832">
        <property type="entry name" value="S1_IF1_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 6 10" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="domain" description="S1-like" evidence="9">
        <location>
            <begin position="74"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="54"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG94887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="160" mass="19169" checksum="834DA2FA1C6E1E64" modified="2017-02-15" version="1">MFDKISFFFFFFCYVYFLYLTNELSLKRSCFINPNNKIDIWKKTISEIYKKSTLNEKKKIIQNLKRRHNNLKNNILRGKENDVIEMNGTVEECLANTNFIVKISNGEKFLCFISGKLRINKVKINLGDLVKIQVHKLDFEKRRGRIIFRYLQQATLKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQY4</accession>
    <name>A0A1J1GQY4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00115600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526272.1">
        <property type="nucleotide sequence ID" value="XM_028674376.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQY4"/>
    <dbReference type="GeneID" id="39729681"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00115600"/>
    <dbReference type="OMA" id="YIITINE"/>
    <dbReference type="OrthoDB" id="372094at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="12"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="168"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="315"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="500"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="531" mass="63679" checksum="B2AED3AFBD0BB5BA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRA4</accession>
    <name>A0A1J1GRA4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00222300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527641.1">
        <property type="nucleotide sequence ID" value="XM_028670938.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRA4"/>
    <dbReference type="GeneID" id="39730750"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00222300"/>
    <dbReference type="OMA" id="FQNVCII"/>
    <dbReference type="OrthoDB" id="383152at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="1">
        <location>
            <begin position="454"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="665" mass="80635" checksum="38AB87B009879A08" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS40</accession>
    <name>A0A1J1GS40_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Eukaryotic translation initiation factor 2-alpha kinase PK4</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Protein kinase PK4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="23" type="primary">PK4</name>
        <name evidence="23" type="ORF">PGAL8A_00156700</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">During the asexual blood stage, phosphorylates translation factor eIF2alpha in late schizonts resulting in protein translation inhibition. Plays a role in trophozoite differentiation into schizonts.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:17990"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:46609"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="16">May form oligomers in response to stress; oligomerization may result in catalytic activity. Interacts with BIP; the interaction is disrupted in response to stress.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526680.1">
        <property type="nucleotide sequence ID" value="XM_028675117.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730092"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00156700"/>
    <dbReference type="OMA" id="NTIMERY"/>
    <dbReference type="OrthoDB" id="1405469at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004694">
        <property type="term" value="F:eukaryotic translation initiation factor 2alpha kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000516">
        <property type="entry name" value="Protein kinase PK4, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050339">
        <property type="entry name" value="CC_SR_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042:SF160">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 23" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 21" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-0652">Protein synthesis inhibitor</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="21" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="21" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="34"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="291"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="491"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="22">
        <location>
            <begin position="2467"/>
            <end position="2764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="1998"/>
            <end position="2047"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="2364"/>
            <end position="2390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="2494"/>
            <end position="2515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="2802"/>
            <end position="2874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="1998"/>
            <end position="2007"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="2025"/>
            <end position="2039"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="2378"/>
            <end position="2390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="20">
        <location>
            <begin position="2494"/>
            <end position="2511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="2802"/>
            <end position="2871"/>
        </location>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="2135"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00037982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00054050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00062343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00071199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00076829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="CRG93859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2910" mass="346938" checksum="60C49AC99C6F1A46" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS80</accession>
    <name>A0A1J1GS80_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">phosphoenolpyruvate carboxykinase (ATP)</fullName>
            <ecNumber evidence="3">4.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PEPCK</name>
        <name evidence="10" type="ORF">PGAL8A_00253900</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>oxaloacetate + ATP = phosphoenolpyruvate + ADP + CO2</text>
            <dbReference type="Rhea" id="RHEA:18617"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.49" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527947.1">
        <property type="nucleotide sequence ID" value="XM_028671279.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS80"/>
    <dbReference type="GeneID" id="39731067"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00253900"/>
    <dbReference type="OMA" id="VTIKHNP"/>
    <dbReference type="OrthoDB" id="184182at2759"/>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004612">
        <property type="term" value="F:phosphoenolpyruvate carboxykinase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00484">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.8.10:FF:000001">
        <property type="entry name" value="Phosphoenolpyruvate carboxykinase (ATP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.449.10:FF:000006">
        <property type="entry name" value="Phosphoenolpyruvate carboxykinase (ATP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.449.10">
        <property type="entry name" value="Phosphoenolpyruvate Carboxykinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.8.10">
        <property type="entry name" value="Phosphoenolpyruvate Carboxykinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00453">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001272">
        <property type="entry name" value="PEP_carboxykinase_ATP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013035">
        <property type="entry name" value="PEP_carboxykinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008210">
        <property type="entry name" value="PEP_carboxykinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015994">
        <property type="entry name" value="PEPCK_ATP_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00224">
        <property type="entry name" value="pckA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006820">
        <property type="entry name" value="PRK09344.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006821">
        <property type="entry name" value="PRK09344.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031:SF0">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYKINASE ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01293">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006294">
        <property type="entry name" value="PEP_crbxkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68923">
        <property type="entry name" value="PEP carboxykinase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53795">
        <property type="entry name" value="PEP carboxykinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00532">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="4" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="8 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG95134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="583" mass="66121" checksum="203CA1316B80F1AE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSV7</accession>
    <name>A0A1J1GSV7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00277700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528388.1">
        <property type="nucleotide sequence ID" value="XM_028671769.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSV7"/>
    <dbReference type="GeneID" id="39731310"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00277700"/>
    <dbReference type="OMA" id="YVDYCIE"/>
    <dbReference type="OrthoDB" id="3945418at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051945">
        <property type="entry name" value="RRM_MRD1_RNA_proc_ribogen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN 14B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039:SF5">
        <property type="entry name" value="RNA-BINDING PROTEIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="262"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="356"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="819"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="863"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="356"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="377"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="428"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="865"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="889"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="927"/>
            <end position="942"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="954" mass="114534" checksum="9E124348F9698CA1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSY1</accession>
    <name>A0A1J1GSY1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tubulin--tyrosine ligase, putative</fullName>
            <ecNumber evidence="4">6.3.2.25</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00385900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.25" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526976.1">
        <property type="nucleotide sequence ID" value="XM_028670201.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSY1"/>
    <dbReference type="GeneID" id="39732389"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00385900"/>
    <dbReference type="OMA" id="NIKMQPR"/>
    <dbReference type="OrthoDB" id="202825at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070740">
        <property type="term" value="F:tubulin-glutamic acid ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004835">
        <property type="term" value="F:tubulin-tyrosine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004344">
        <property type="entry name" value="TTL/TTLL_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12241">
        <property type="entry name" value="TUBULIN POLYGLUTAMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12241:SF147">
        <property type="entry name" value="TUBULIN POLYGLUTAMYLASE TTLL7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03133">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51221">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 4" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="508" mass="60690" checksum="57D9D201AEC31889" modified="2017-02-15" version="1">MDECLINHEKNKYDAILKKNKFLYKIQLSNTRYDIIRRVVQDSKYWVESPPDSNDWDVIWIDTSISEERFRKLKKFQKINHFIGMRGITRKDELSRNLKKMKKNFPQSYNFFPLTWILPNEISDFKNYYKQKSNSKTYIVKLKNSCQGKGIYLTKKLDNINKYESCIIQKYIHKPLLINGLKFDIRLYVLITGCDPLRIFLHEDGLVRFSIEKYKLPKSKNLKQVNMHLTNFAINKKSDKFENSLNPDDATIGHKRSWKVVLEKLKEQGLPMDSIMTKIEHMIVKTICSIQPELKHFYNSAHISDYSNSMCFEILGFDILLDHKLKPWLLEVNHSPSFRTCSMVDEKVKYAVIRDTLNILYMRSKYRLIHIQEYLNLQKFRKKYNHLLVKNKKELKEKLTISRFQYENKNLGGYKRIYPLEELLDYENLILYVSNAWNKSIGIPYSMKKDSFEYLFEEQIKKKKMAKEKLSINDKSTEEQVFSQNNLEYNKYYSHRAHVNISNCSTSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSZ7</accession>
    <name>A0A1J1GSZ7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="17">DNA repair helicase, putative</fullName>
            <ecNumber evidence="17">3.6.4.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">PGAL8A_00279900</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="17"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528410.1">
        <property type="nucleotide sequence ID" value="XM_028671793.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSZ7"/>
    <dbReference type="GeneID" id="39731332"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00279900"/>
    <dbReference type="OMA" id="NCATIVA"/>
    <dbReference type="OrthoDB" id="19182at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070182">
        <property type="term" value="F:DNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045910">
        <property type="term" value="P:negative regulation of DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904430">
        <property type="term" value="P:negative regulation of t-circle formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010569">
        <property type="term" value="P:regulation of double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090657">
        <property type="term" value="P:telomeric loop disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18788">
        <property type="entry name" value="SF2_C_XPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001352">
        <property type="entry name" value="DNA repair helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006554">
        <property type="entry name" value="Helicase-like_DEXD_c2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010614">
        <property type="entry name" value="RAD3-like_helicase_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013020">
        <property type="entry name" value="Rad3/Chl1-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00604">
        <property type="entry name" value="rad3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472:SF34">
        <property type="entry name" value="REGULATOR OF TELOMERE ELONGATION HELICASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06733">
        <property type="entry name" value="DEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00488">
        <property type="entry name" value="DEXDc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 17" id="KW-0347">Helicase</keyword>
    <keyword evidence="6 17" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="16">
        <location>
            <begin position="25"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="807"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="807"/>
            <end position="825"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="CRG95602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1045" mass="122888" checksum="ABD11ADE40B8E6D7" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSZ9</accession>
    <name>A0A1J1GSZ9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Adenylyl cyclase alpha, putative</fullName>
            <ecNumber evidence="3">4.6.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00276400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.1" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528375.1">
        <property type="nucleotide sequence ID" value="XM_028671753.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSZ9"/>
    <dbReference type="GeneID" id="39731296"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00276400"/>
    <dbReference type="OMA" id="CDFYGGS"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43336:SF3">
        <property type="entry name" value="GUANYLATE CYCLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43336">
        <property type="entry name" value="OXYGEN SENSOR HISTIDINE KINASE RESPONSE REGULATOR DEVS/DOSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="432"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="2">
        <location>
            <begin position="558"/>
            <end position="725"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="912" mass="109438" checksum="4C0EABE3B82941A3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT87</accession>
    <name>A0A1J1GT87_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="8">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00286000</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the PPP phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528471.1">
        <property type="nucleotide sequence ID" value="XM_028671860.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT87"/>
    <dbReference type="GeneID" id="39731393"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00286000"/>
    <dbReference type="OMA" id="TVQMSEN"/>
    <dbReference type="OrthoDB" id="1930084at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07414">
        <property type="entry name" value="MPP_PP1_PPKL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000004">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050341">
        <property type="entry name" value="PP1_catalytic_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031675">
        <property type="entry name" value="STPPase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668">
        <property type="entry name" value="SERINE/THREONINE PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11668:SF300">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16891">
        <property type="entry name" value="STPPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="9">
        <location>
            <begin position="119"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG95663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="304" mass="34964" checksum="9CFCDBB29FEFEFC6" modified="2017-02-15" version="1">MALEIDIDNVISKLIEVRGTRPGKNVNLTENEIKILCLSSREIFLNQPILLELEAPIKICGDIHGQFYDLLRLFEYGGFPPDANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYSVKLWKTFIDCFNCLPVAAIIDEKIFCMHGGLSPELNNMEQIRKITRPTDVPDNGLLCDLLWSDPEKEINGWGENDRGVSFTFGQDVVHNFLRKHELDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPVEKKKTTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT94</accession>
    <name>A0A1J1GT94_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00191500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000028">
        <property type="protein sequence ID" value="CRG94517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527333.1">
        <property type="nucleotide sequence ID" value="XM_028670596.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT94"/>
    <dbReference type="GeneID" id="39730440"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00191500"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="298"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="253"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="333" mass="41138" checksum="090A89D2F6F2E7BC" modified="2017-02-15" version="1">MLPYQINSYKIFINFNNLFYFILFLFIKLIYSFLLKMTSFFFTHYPYINFIFFIFSNVNLFLFFARLRETKKNLIEKLILNKIIHKNNNNNKLNGKPNLIKEDIEWIKDKKNMLKELLIRNSQEMLNLSLWVKNKRCRESLINEKILEEIETWEQWKNAKDEEFAKQEDYKSPENMYGCFAKLLWHIDQKRLKKIEDATQKDIKIIHLNKRYISPIREILEMKISTYNETLRSTITEFEEIFKSYYWITWKELKELEKRKSTLEKKKEEIIKENEKLQMEITIKNDEERTVKKRLRKFRKGERSHEIKKKKKKKKSKKERIYISMFFHNLKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTD9</accession>
    <name>A0A1J1GTD9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DEAD-box helicase OB fold domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00196100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527381.1">
        <property type="nucleotide sequence ID" value="XM_028670650.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTD9"/>
    <dbReference type="GeneID" id="39730488"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00196100"/>
    <dbReference type="OMA" id="IILTNVH"/>
    <dbReference type="OrthoDB" id="360515at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF91">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE PRP16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box helicase OB fold" evidence="6">
        <location>
            <begin position="870"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="237"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="317"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="329"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="342"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG94566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="962" mass="115786" checksum="90186290EA11862D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTH2</accession>
    <name>A0A1J1GTH2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PhIL1 interacting protein PIP3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00302400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528620.1">
        <property type="nucleotide sequence ID" value="XM_028672026.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTH2"/>
    <dbReference type="GeneID" id="39731557"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00302400"/>
    <dbReference type="OMA" id="HFTCGIN"/>
    <dbReference type="OrthoDB" id="330677at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="267" mass="30613" checksum="20D84B2CC251F792" modified="2017-02-15" version="1">MSESTYKDTQIFKPNGTNIYDDHLGEVYKLKDNISAEELFHSKNIYRDVKSNVIPGPVKTTTIEKVTKIPKIIFKERPLDTKKEKKEKKVITKEVEIENVVEVIENKEKVVYNEVKVPKYVDVPIIQPRQEVCYQQISKNIPRGVELVITQTLEVPKIKPKYVEIPVPIYVPCYIEVPIPAQYIPTEQNEEKDYFASGISNSSKFSKRANFYNSSLAHSQNFNTPITLNQNLNINDEKSLDFSSKCSIPNISSEQKNVEKMVIAGNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTS8</accession>
    <name>A0A1J1GTS8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00310200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528698.1">
        <property type="nucleotide sequence ID" value="XM_028672113.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTS8"/>
    <dbReference type="GeneID" id="39731635"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00310200"/>
    <dbReference type="OMA" id="IKELYCQ"/>
    <dbReference type="OrthoDB" id="10036721at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17756">
        <property type="entry name" value="MCM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000501">
        <property type="entry name" value="DNA replication licensing factor MCM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054125">
        <property type="entry name" value="MCM5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF42">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21933">
        <property type="entry name" value="MCM5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="6">
        <location>
            <begin position="365"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="758" mass="85584" checksum="B25C0CA5770FE89B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTT4</accession>
    <name>A0A1J1GTT4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Derlin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00211500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the derlin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527533.1">
        <property type="nucleotide sequence ID" value="XM_028670818.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTT4"/>
    <dbReference type="GeneID" id="39730642"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00211500"/>
    <dbReference type="OrthoDB" id="19102at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007599">
        <property type="entry name" value="DER1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11009">
        <property type="entry name" value="DER1-LIKE PROTEIN, DERLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04511">
        <property type="entry name" value="DER1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012610882" description="Derlin" evidence="8">
        <location>
            <begin position="25"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="231"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="276"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="306"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="353" mass="41989" checksum="E808A65F5A6F9624" modified="2017-02-15" version="1">MNIIFYTVLILIYIINIKKTDVQCAKIYDFKKIKITYSFNSLREFKKKKINDLNDAFYKKGKFFHIRIPKKTIKKINLYSRDIYNEKIINFIKNKKKNKLYYLCIPNNNKFVLKNKNKNKVLQLFFEKKKLLELYLYKFKSSLLYKYRDIKIITKIFLFSSLIITTLNIFGLKPEDIALHSKRVIRSFEFYRIVTSALFYGDISLYVLTNIYMLYVQSQELEKLLGSSETLSFYLSQIVILSFICSYLKKPFYSTAILKSLLFLNCMLNPYQKSKLIFGISIYNIYLPYLSILIDILHAQNLKASLSGILGVTSGSIYYFLNIYLYEKFNKKFFKIPMSLKNYLDSLNSEELF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU05</accession>
    <name>A0A1J1GU05_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00320900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000047">
        <property type="protein sequence ID" value="CRG95996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528804.1">
        <property type="nucleotide sequence ID" value="XM_028672231.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU05"/>
    <dbReference type="GeneID" id="39731742"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00320900"/>
    <dbReference type="OMA" id="HNINTDK"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012565844" evidence="2">
        <location>
            <begin position="23"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="803" mass="93345" checksum="2D02CCB7A7414525" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU41</accession>
    <name>A0A1J1GU41_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00318800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528783.1">
        <property type="nucleotide sequence ID" value="XM_028672208.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU41"/>
    <dbReference type="GeneID" id="39731721"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00318800"/>
    <dbReference type="OMA" id="MKNMGGK"/>
    <dbReference type="OrthoDB" id="1919336at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.30.10:FF:000037">
        <property type="entry name" value="High mobility group protein B2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050342">
        <property type="entry name" value="HMGB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112">
        <property type="entry name" value="HIGH MOBILITY GROUP PROTEIN DSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48112:SF22">
        <property type="entry name" value="MITOCHONDRIAL TRANSCRIPTION FACTOR A, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00886">
        <property type="entry name" value="HIGHMOBLTY12"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="5">
        <location>
            <begin position="30"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="3">
        <location>
            <begin position="30"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="106" mass="12297" checksum="66A7CEFD5B2A3CB2" modified="2017-02-15" version="1">MEGKKNKETKNNGGKEVRKRRKNKKDPHAPKRSLSAYMFFAKEKRAEIIRNDPELSKDVATVGKMIGEAWNKLGEKEKIPFEKKAQEDKIRYEKEKAEYASSKVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU52</accession>
    <name>A0A1J1GU52_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome b-c1 complex subunit 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00298300</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the UQCRH/QCR6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528579.1">
        <property type="nucleotide sequence ID" value="XM_028671981.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU52"/>
    <dbReference type="GeneID" id="39731516"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00298300"/>
    <dbReference type="OMA" id="GHCLGQH"/>
    <dbReference type="OrthoDB" id="405848at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.20:FF:000001">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.20">
        <property type="entry name" value="Ubiquinol-cytochrome C reductase hinge domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003422">
        <property type="entry name" value="Cyt_b-c1_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023184">
        <property type="entry name" value="Ubol_cytC_Rdtase_hinge_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036811">
        <property type="entry name" value="Ubol_cytC_Rdtase_hinge_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15336:SF0">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15336">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 7.8 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02320">
        <property type="entry name" value="UCR_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000019">
        <property type="entry name" value="Bc1_11K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81531">
        <property type="entry name" value="Non-heme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 10" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Ubiquinol-cytochrome C reductase hinge" evidence="12">
        <location>
            <begin position="27"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="36"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="50"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG95771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="88" mass="10519" checksum="A91527E355B54932" modified="2017-02-15" version="1">MSYPYNPEFFVRYPKFKEREEKDRIVDPKIELEKKCAVKCVRPVNEYQNCVSRVKARTDDKGNCLGQYEELYVCIDHCVAKDLFNYLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU81</accession>
    <name>A0A1J1GU81_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Vesicle-associated membrane protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00199000</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527408.1">
        <property type="nucleotide sequence ID" value="XM_028670680.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU81"/>
    <dbReference type="GeneID" id="39730517"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00199000"/>
    <dbReference type="OMA" id="VTKYMGY"/>
    <dbReference type="OrthoDB" id="264603at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090158">
        <property type="term" value="P:endoplasmic reticulum membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061817">
        <property type="term" value="P:endoplasmic reticulum-plasma membrane tethering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000535">
        <property type="entry name" value="MSP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008962">
        <property type="entry name" value="PapD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016763">
        <property type="entry name" value="VAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10809:SF6">
        <property type="entry name" value="AT11025P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10809">
        <property type="entry name" value="VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00635">
        <property type="entry name" value="Motile_Sperm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019693">
        <property type="entry name" value="VAMP-associated"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49354">
        <property type="entry name" value="PapD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50202">
        <property type="entry name" value="MSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="223"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="MSP" evidence="8">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="186"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="241" mass="27768" checksum="81A8212DF0872EA4" modified="2017-02-15" version="1">MKLLKVIPEKNIEFPLVHFQAVTQIVKLENISEKKVAFKIKTTAPNNYLVRPSFGLINVKETVEIQIILQPLSDKDNISNDKFQVQCLNVEDDTTVDKQFWVTVNKNEIQDHKLIVVLNDENSNKLTHSCLPSNNIPLTEMNNKNSQNLNYTDNNNINQEDTNLSEGLKGGLPGMQRKYHELLNYCVFVDKQKAALEKENESLKNQLKALNSNYNKFFIDNKYIPIIIVILAIVTKYLGYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUA4</accession>
    <name>A0A1J1GUA4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Centrin-4, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">CEN4</name>
        <name evidence="9" type="ORF">PGAL8A_00332800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the centrin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528918.1">
        <property type="nucleotide sequence ID" value="XM_028672358.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUA4"/>
    <dbReference type="GeneID" id="39731858"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00332800"/>
    <dbReference type="OMA" id="SAWKNDP"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000362">
        <property type="entry name" value="Centrin-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF59">
        <property type="entry name" value="EF-HAND SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="8">
        <location>
            <begin position="14"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="8">
        <location>
            <begin position="87"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="8">
        <location>
            <begin position="123"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG96113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="167" mass="19682" checksum="61532456B2A73012" modified="2017-02-15" version="1">MIIENNKEFTINEDIEKEICECFSLFDTNKCGYIDIREFYFALKSLGLNFKKEEVKNLFLQIKKSTDDKLNFDEFFHVASQNIHKRYNDEEIEQIFSLFDPNDTGKITLHSLKKVCEDIGENISDNELNNMIEYADKNNDKVIDKEEFKKILISAWKNDPLSDIDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUE3</accession>
    <name>A0A1J1GUE3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein uS5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">40S ribosomal protein S2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00206200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the universal ribosomal protein uS5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527480.1">
        <property type="nucleotide sequence ID" value="XM_028670760.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUE3"/>
    <dbReference type="GeneID" id="39730589"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00206200"/>
    <dbReference type="OMA" id="PYEEWSD"/>
    <dbReference type="OrthoDB" id="10253125at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.20:FF:000002">
        <property type="entry name" value="40S ribosomal protein S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000004">
        <property type="entry name" value="40S ribosomal protein S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000851">
        <property type="entry name" value="Ribosomal_uS5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005324">
        <property type="entry name" value="Ribosomal_uS5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005711">
        <property type="entry name" value="Ribosomal_uS5_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_uS5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01020">
        <property type="entry name" value="uS5_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13718:SF4">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13718">
        <property type="entry name" value="RIBOSOMAL S SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03719">
        <property type="entry name" value="Ribosomal_S5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="S5 DRBM" evidence="9">
        <location>
            <begin position="87"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="17"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG94665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="271" mass="29885" checksum="C42850810ABA791C" modified="2017-02-15" version="1">MEADRGGFSKGFGRGVRGTRGRGRGRGRGRGSAEDDLKNWVPVTKLGRLVKEGKISSIEEIYLHSLPIKEYQIIDYFFQPNECAHPLKDDVVKIMPVQKQTRAGQRTRFKAFVAIGDGNGHCGLGVKCAKEVATAIRGAIIAAKLSLIPVRRGYWGNKIGDPHTVPMKVSGKCGSVRIRLVPAPRGTQIVGAPTTKKMLNFAGIKDCFSSSCGKTKTRGNFLRAIFNALSKTYGYLTPDLWKVTKFDKSPYEEWSDFLETYQNLKGIKATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUK0</accession>
    <name>A0A1J1GUK0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Mon2/Sec7/BIG1-like dimerisation and cyclophilin-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00211800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527536.1">
        <property type="nucleotide sequence ID" value="XM_028670822.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730645"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00211800"/>
    <dbReference type="OMA" id="NMFELHI"/>
    <dbReference type="OrthoDB" id="392523at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032629">
        <property type="entry name" value="DCB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010301">
        <property type="entry name" value="RRP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13026">
        <property type="entry name" value="NNP-1 PROTEIN NOVEL NUCLEAR PROTEIN 1 NOP52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13026:SF0">
        <property type="entry name" value="RIBOSOMAL RNA PROCESSING 1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16213">
        <property type="entry name" value="DCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="600"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="628"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1627"/>
            <end position="1650"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1967"/>
            <end position="1984"/>
        </location>
    </feature>
    <feature type="domain" description="Mon2/Sec7/BIG1-like dimerisation and cyclophilin-binding" evidence="8">
        <location>
            <begin position="7"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="314"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="761"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="883"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1062"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1338"/>
            <end position="1367"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="2610"/>
            <end position="2655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="326"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="898"/>
            <end position="907"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3143" mass="379093" checksum="EA2A427F3D0186EB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUP6</accession>
    <name>A0A1J1GUP6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00323800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000051">
        <property type="protein sequence ID" value="CRG96025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528833.1">
        <property type="nucleotide sequence ID" value="XM_028672263.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUP6"/>
    <dbReference type="GeneID" id="39731771"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00323800"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="136" mass="16359" checksum="53A58C4DF16E2045" modified="2017-02-15" version="1">MKIFTLCLNIFTFIILTWIFHCFYKYDSSKSIIHKDTLQIKHKLKDKRTLAEGNILKKNQTHIKERKEHYLSGEKDNKNEKVISLKNMYSMWIIPFYLLMCELLSIQENKISSICRDHMLTIYRCNNSSMAIIDRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUV5</accession>
    <name>A0A1J1GUV5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fam-j protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00329700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528889.1">
        <property type="nucleotide sequence ID" value="XM_028672326.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUV5"/>
    <dbReference type="GeneID" id="39731827"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00329700"/>
    <dbReference type="OMA" id="CSTINDE"/>
    <dbReference type="OrthoDB" id="10578264at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013334868" description="Fam-j protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="353"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="400"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="431"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="458"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="947" mass="109557" checksum="0D1907377EEF047A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUV9</accession>
    <name>A0A1J1GUV9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HECT-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00346000</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.26"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.26" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529047.1">
        <property type="nucleotide sequence ID" value="XM_028672501.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731990"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00346000"/>
    <dbReference type="OrthoDB" id="8068875at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2410.10:FF:000003">
        <property type="entry name" value="probable E3 ubiquitin-protein ligase HERC4 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2160.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2410.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.10">
        <property type="entry name" value="Hect, E3 ligase catalytic domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044611">
        <property type="entry name" value="E3A/B/C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000569">
        <property type="entry name" value="HECT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035983">
        <property type="entry name" value="Hect_E3_ubiquitin_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45700:SF2">
        <property type="entry name" value="UBIQUITIN-PROTEIN LIGASE E3C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00632">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00119">
        <property type="entry name" value="HECTc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56204">
        <property type="entry name" value="Hect, E3 ligase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50237">
        <property type="entry name" value="HECT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="346"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="390"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="800"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="842"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="domain" description="HECT" evidence="8">
        <location>
            <begin position="1224"/>
            <end position="1701"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="886"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="5">
        <location>
            <position position="1669"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG96242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1701" mass="202873" checksum="8A2249A8F220DAFB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV03</accession>
    <name>A0A1J1GV03_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00350800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529095.1">
        <property type="nucleotide sequence ID" value="XM_028672554.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV03"/>
    <dbReference type="GeneID" id="39732038"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00350800"/>
    <dbReference type="OMA" id="IFMNTYK"/>
    <dbReference type="OrthoDB" id="270602at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02958">
        <property type="entry name" value="UAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14273">
        <property type="entry name" value="UBA_TAP-C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006577">
        <property type="entry name" value="UAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050730">
        <property type="entry name" value="UBX_domain-protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23322">
        <property type="entry name" value="FAS-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23322:SF6">
        <property type="entry name" value="UBX DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13899">
        <property type="entry name" value="Thioredoxin_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14555">
        <property type="entry name" value="UBA_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00594">
        <property type="entry name" value="UAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UAS" evidence="2">
        <location>
            <begin position="116"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="347" mass="41535" checksum="DB1E11782A6A45E5" modified="2017-02-15" version="1">MISKNDIDEFLRNTEDTTEETALYYLEMCNGNCKDALNLYYEINGGNNSENDRRNAEEQQLKEYNHHDTNECNENIRSPDKHFSQKLIHDMDESNFLHFREINKKEKKTKIDLGGTFEKLFSPPESLICSLSFEEVRKKSKEENKFILVNIQNSEFDSMRLNRDIWNNDIIQQILKDFFIFWLRYEYEQEAMIFMNTYKVNKLPYICVLCKRTGRLLKVWNTKHFEDPVCAQSQLYEFIEMIELKNNVNNINNNKNNNSVNNTLNDLEKNKINYNVDDNKLYNTTKEIKYIEEIQKDIDKNINPSNPLNLSENKERTSNNENIKDYNKINNELSELHKLRLQRLQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV87</accession>
    <name>A0A1J1GV87_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00366400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529244.1">
        <property type="nucleotide sequence ID" value="XM_028672719.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732194"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00366400"/>
    <dbReference type="OMA" id="NIYMNIY"/>
    <dbReference type="OrthoDB" id="372814at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="86"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="568"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1115"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="93"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="130"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="160"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="179"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1523" mass="182422" checksum="530AEF51BBC61938" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVD5</accession>
    <name>A0A1J1GVD5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Vesicle-fusing ATPase</fullName>
            <ecNumber evidence="6">3.6.4.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">NSF</name>
        <name evidence="8" type="ORF">PGAL8A_00002300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.6" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528069.1">
        <property type="nucleotide sequence ID" value="XM_028671414.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVD5"/>
    <dbReference type="GeneID" id="39728545"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00002300"/>
    <dbReference type="OMA" id="CFDNEIA"/>
    <dbReference type="OrthoDB" id="9982946at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005795">
        <property type="term" value="C:Golgi stack"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043001">
        <property type="term" value="P:Golgi to plasma membrane protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035494">
        <property type="term" value="P:SNARE complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000115">
        <property type="entry name" value="N-ethylmaleimide-sensitive fusion protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000166">
        <property type="entry name" value="vesicle-fusing ATPase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000187">
        <property type="entry name" value="Vesicular-fusion ATPase SEC18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029067">
        <property type="entry name" value="CDC48_domain_2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039812">
        <property type="entry name" value="Vesicle-fus_ATPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23078:SF3">
        <property type="entry name" value="VESICLE-FUSING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23078">
        <property type="entry name" value="VESICULAR-FUSION PROTEIN NSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="ADC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54585">
        <property type="entry name" value="Cdc48 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="7">
        <location>
            <begin position="271"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="7">
        <location>
            <begin position="552"/>
            <end position="691"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="768" mass="87766" checksum="4E584ABE8E7DA131" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVE7</accession>
    <name>A0A1J1GVE7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">dolichyl-diphosphooligosaccharide--protein glycotransferase</fullName>
            <ecNumber evidence="6">2.4.99.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">PGAL8A_00343200</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a di-trans,poly-cis-dolichyl diphosphooligosaccharide + L-asparaginyl-[protein] = N(4)-(oligosaccharide-(1-&gt;4)-N-acetyl-beta-D-glucosaminyl-(1-&gt;4)-N-acetyl-beta-D-glucosaminyl)-L-asparaginyl-[protein] + a di-trans,poly-cis-dolichyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22980"/>
            <dbReference type="Rhea" id="RHEA-COMP:12804"/>
            <dbReference type="Rhea" id="RHEA-COMP:12805"/>
            <dbReference type="Rhea" id="RHEA-COMP:19506"/>
            <dbReference type="Rhea" id="RHEA-COMP:19509"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:50347"/>
            <dbReference type="ChEBI" id="CHEBI:57497"/>
            <dbReference type="ChEBI" id="CHEBI:57570"/>
            <dbReference type="ChEBI" id="CHEBI:132529"/>
            <dbReference type="EC" id="2.4.99.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endomembrane system</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the STT3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.99.18" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529019.1">
        <property type="nucleotide sequence ID" value="XM_028672470.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVE7"/>
    <dbReference type="GeneID" id="39731962"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00343200"/>
    <dbReference type="OMA" id="TWYAIGT"/>
    <dbReference type="OrthoDB" id="10261066at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004579">
        <property type="term" value="F:dolichyl-diphosphooligosaccharide-protein glycotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003674">
        <property type="entry name" value="Oligo_trans_STT3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048999">
        <property type="entry name" value="STT3-PglB_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048307">
        <property type="entry name" value="STT3_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13872">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13872:SF1">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT STT3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02516">
        <property type="entry name" value="STT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21436">
        <property type="entry name" value="STT3-PglB_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0464">Manganese</keyword>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 19" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="147"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="237"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="274"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="301"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="334"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="388"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="418"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="442"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="633"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="domain" description="Oligosaccharyl transferase STT3 N-terminal" evidence="17">
        <location>
            <begin position="52"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="STT3/PglB/AglB core" evidence="18">
        <location>
            <begin position="701"/>
            <end position="773"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF21436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="CRG96214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="871" mass="103232" checksum="3D67D8FC88EC9815" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVH8</accession>
    <name>A0A1J1GVH8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Dolichol-phosphate mannosyltransferase subunit 1</fullName>
            <ecNumber evidence="13">2.4.1.83</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">DPM1</name>
        <name evidence="15" type="ORF">PGAL8A_00369100</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a di-trans,poly-cis-dolichyl phosphate + GDP-alpha-D-mannose = a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate + GDP</text>
            <dbReference type="Rhea" id="RHEA:21184"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 13">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Component of the dolichol-phosphate mannose (DPM) synthase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 13">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 13">Belongs to the glycosyltransferase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.83" evidence="13"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529271.1">
        <property type="nucleotide sequence ID" value="XM_028672749.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVH8"/>
    <dbReference type="GeneID" id="39732221"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00369100"/>
    <dbReference type="OMA" id="KCFRREV"/>
    <dbReference type="OrthoDB" id="2603at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004582">
        <property type="term" value="F:dolichyl-phosphate beta-D-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006066">
        <property type="term" value="P:alcohol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006720">
        <property type="term" value="P:isoprenoid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035269">
        <property type="term" value="P:protein O-linked glycosylation via mannose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06442">
        <property type="entry name" value="DPM1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000036">
        <property type="entry name" value="Dolichol-phosphate mannosyltransferase subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039528">
        <property type="entry name" value="DPM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43398">
        <property type="entry name" value="DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43398:SF1">
        <property type="entry name" value="DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 13 15" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0464">Manganese</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 13 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="14">
        <location>
            <begin position="8"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00006739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU365083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG96466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="240" mass="27938" checksum="2BF134A44B1E553E" modified="2017-02-15" version="1">MSSANVYSIILPTYNEKENLPYIIYMIINEMKKKMIDFEIILVDDNSEDKTANVYKKLQTIFKEEKLLLIERKGKLGLGSAYIDALKIVSGNFVIIMDADLSHHPKYINDFIEKQKETNCDIVTGSRYNKYGGISGWSFKRVLISRVANFLSQFLLFINLSDLTGSFRLYRTETLKEIIEKIEGKGYLFQMEVIVRANKLNKKIEEVGYVFVDRLFGKSKLSSYDIFQFFFGLLKLFWSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVQ8</accession>
    <name>A0A1J1GVQ8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CBF1-interacting co-repressor CIR N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00013900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528181.1">
        <property type="nucleotide sequence ID" value="XM_028671539.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVQ8"/>
    <dbReference type="GeneID" id="39728661"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00013900"/>
    <dbReference type="OMA" id="IKKGHYI"/>
    <dbReference type="OrthoDB" id="2159131at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="241" mass="29443" checksum="F0F6629E0B2E4165" modified="2017-02-15" version="1">MGGHGGLNILPQKKWNVYRNDVQYKVNYDENKLIKEKGEIERKKNEHLFENYINELKNNINNNEGKIEYNEHINLFIEEEKEINRRKKLHEEYLIKNGHYIYNDNKFNGINCIYDKTNNTKIISDFDKIKISQNQWFLNRQKNVFLKNDGIELDNKNNTTLNKCYSGVKEKFLQKKTFCENEVRENDTDTFKYENKKKKESKNKYEHIKKLIKYKKEKEKKKNKRKKEKKMKMKIKMRKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVR8</accession>
    <name>A0A1J1GVR8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DnaJ protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00364400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529225.1">
        <property type="nucleotide sequence ID" value="XM_028672698.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVR8"/>
    <dbReference type="GeneID" id="39732174"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00364400"/>
    <dbReference type="OMA" id="DDRMRKK"/>
    <dbReference type="OrthoDB" id="552049at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030544">
        <property type="term" value="F:Hsp70 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071218">
        <property type="term" value="P:cellular response to misfolded protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051100">
        <property type="entry name" value="DnaJ_subfamily_B/C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43908">
        <property type="entry name" value="AT29763P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43908:SF3">
        <property type="entry name" value="AT29763P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="98"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="361" mass="43739" checksum="499628F79589AE3E" modified="2017-02-15" version="1">MIGNKEEAFECFNLALKYMNIGNYAHAKKLFLKAKRMFPDMEINDKLKICEEELKKTENIGTEKVTNNNDIYRENQNRMHERHKKKNDLMEKILKTNNYYEILGIPKNSNDETIRSAYKKLAKLYHPDKNKEKGAEEAFKKVSKAFQHLINKEKRYEYDNNSEEDIHQNFRTTHYYYNDDSFTPEDLFRNFFGINFATCNNRTFRTNINSNRAYTTTNNNVNNSQRNYSLIQILIFLIMFIIFFLSSHFEHPKAVYSLQKTSYFDTINYTTLNKVRFYTKRTFNYTYPRNSDSRFQIEYEVEYKYYEHECLILSKKIKNDYYKEKSKYNQKLNYQEIPESCIKLKTLEAQYNNYILKLKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVS7</accession>
    <name>A0A1J1GVS7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tyrosine-protein kinase ephrin type A/B receptor-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00414600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529370.1">
        <property type="nucleotide sequence ID" value="XM_028672859.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVS7"/>
    <dbReference type="GeneID" id="39732676"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00414600"/>
    <dbReference type="OMA" id="FCNYGEY"/>
    <dbReference type="OrthoDB" id="376968at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.50.10">
        <property type="entry name" value="Tumor Necrosis Factor Receptor, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01411">
        <property type="entry name" value="Ephrin_rec_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="337"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="406"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="445"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="499"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="549"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="575"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="630"/>
            <end position="653"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="947" mass="115968" checksum="7984400D90F19E17" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVU2</accession>
    <name>A0A1J1GVU2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00366900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529249.1">
        <property type="nucleotide sequence ID" value="XM_028672725.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732199"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00366900"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1441"/>
            <end position="1460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1470" mass="179654" checksum="BED4FC02810A06DC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVU6</accession>
    <name>A0A1J1GVU6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00425400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529478.1">
        <property type="nucleotide sequence ID" value="XM_028672980.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVU6"/>
    <dbReference type="GeneID" id="39732786"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00425400"/>
    <dbReference type="OMA" id="KGQHNIY"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="58"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="82" mass="9922" checksum="86BF5DE68CB104A8" modified="2017-02-15" version="1">MITYLKKVKLNKDKKFLEIIGRENFGTVKIPESLRSFYEKKKEEIELKKKKLEEKKKKMDKVTISKERKNKFKSSKGQHNIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVX4</accession>
    <name>A0A1J1GVX4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tyrosine-protein kinase ephrin type A/B receptor-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00416800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529391.1">
        <property type="nucleotide sequence ID" value="XM_028672883.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732699"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00416800"/>
    <dbReference type="OrthoDB" id="413581at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00185">
        <property type="entry name" value="TNFRSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.50.10">
        <property type="entry name" value="Tumor Necrosis Factor Receptor, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011641">
        <property type="entry name" value="Tyr-kin_ephrin_A/B_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46967">
        <property type="entry name" value="INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN,N-TERMINAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46967:SF2">
        <property type="entry name" value="SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07699">
        <property type="entry name" value="Ephrin_rec_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01411">
        <property type="entry name" value="Ephrin_rec_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="222"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="315"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="722"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="774"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="825"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="862"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1023"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1054"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine-protein kinase ephrin type A/B receptor-like" evidence="4">
        <location>
            <begin position="70"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="548"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="920"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1116"/>
            <end position="1143"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1790"/>
            <end position="1817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="554"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2694" mass="322529" checksum="A2749A4EB1576AE8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW06</accession>
    <name>A0A1J1GW06_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GTPase activator, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00419900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529423.1">
        <property type="nucleotide sequence ID" value="XM_028672918.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW06"/>
    <dbReference type="GeneID" id="39732731"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00419900"/>
    <dbReference type="OMA" id="IYVFEKI"/>
    <dbReference type="OrthoDB" id="294251at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000033">
        <property type="entry name" value="GTPase-activating protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF9">
        <property type="entry name" value="GTPASE ACTIVATING PROTEIN AND CENTROSOME-ASSOCIATED, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="3">
        <location>
            <begin position="226"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="588"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="861"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="588"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="613"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="625"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="637"/>
            <end position="653"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="989" mass="117478" checksum="814093DC835A9CE5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW11</accession>
    <name>A0A1J1GW11_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA-directed RNA polymerase III subunit RPC3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00373300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529313.1">
        <property type="nucleotide sequence ID" value="XM_028672796.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW11"/>
    <dbReference type="GeneID" id="39732263"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00373300"/>
    <dbReference type="OMA" id="YKYMKGC"/>
    <dbReference type="OrthoDB" id="272392at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="806" mass="95464" checksum="65CE10821B79330B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW23</accession>
    <name>A0A1J1GW23_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyridoxal phosphate homeostasis protein</fullName>
            <shortName evidence="2">PLP homeostasis protein</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00432500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529548.1">
        <property type="nucleotide sequence ID" value="XM_028673057.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW23"/>
    <dbReference type="GeneID" id="39732857"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00432500"/>
    <dbReference type="OMA" id="PLEWHMI"/>
    <dbReference type="OrthoDB" id="10264196at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="entry name" value="Alanine racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02087">
        <property type="entry name" value="PLP_homeostasis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011078">
        <property type="entry name" value="PyrdxlP_homeostasis"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00044">
        <property type="entry name" value="YggS family pyridoxal phosphate-dependent enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10146">
        <property type="entry name" value="PROLINE SYNTHETASE CO-TRANSCRIBED BACTERIAL HOMOLOG PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10146:SF14">
        <property type="entry name" value="PYRIDOXAL PHOSPHATE HOMEOSTASIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004848">
        <property type="entry name" value="YBL036c_PLPDEIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="PLP-binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01211">
        <property type="entry name" value="UPF0001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="1 2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2 3">
        <location>
            <position position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR004848-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="242" mass="28414" checksum="BE50CC0F576B724F" modified="2017-02-15" version="1">MKYITNLKNIENKVKTISEQCSVNTPKILIVTKYIGNNEINDIHSYDKKYHFGENYLDSLIEKSEQLPNSIKWHFIGNLQSNKCKNILKVKNLYMIESIDKEKKATLLNNYLKIINEDNLNTNENLKKIRVLIQIKTADDENKTGIIHDNYEEIENIVLYIIQNCNFLIFKGLMTISSLEISKRENSFIILNNIKNRLLNNKTINNYFHKKKFHMSMGMSDDLELAIKHQTTQLRIGRAIFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW48</accession>
    <name>A0A1J1GW48_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00413000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000064">
        <property type="protein sequence ID" value="CRG96548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529353.1">
        <property type="nucleotide sequence ID" value="XM_028672840.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW48"/>
    <dbReference type="GeneID" id="39732660"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00413000"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="210" mass="25643" checksum="55DCEED01D62F5A4" modified="2017-02-15" version="1">MKTLTLYLKITIFLLLIWMYQCFYNCYSYKTLIDKNIFQIKNELKYKRILTEGDIAAKKQTNAEECPKKCPLDNEKNESLVLDLYKNPYNYWFKFKVPIFWERFKNETSQMDHKWKLKKWNVEFQIFSNTKFNDLYSIIRSDIPDKERNEKIDNFMNEFDSEFEEFLLKCKQEMGVNKTECESMKEEGKNEKKNKKSNISKFLCCRFDNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW87</accession>
    <name>A0A1J1GW87_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Zinc finger protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00440000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529622.1">
        <property type="nucleotide sequence ID" value="XM_028673139.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW87"/>
    <dbReference type="GeneID" id="39732933"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00440000"/>
    <dbReference type="OMA" id="MNNNCMS"/>
    <dbReference type="OrthoDB" id="293532at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045877">
        <property type="entry name" value="ZFP36-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12547">
        <property type="entry name" value="CCCH ZINC FINGER/TIS11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12547:SF18">
        <property type="entry name" value="PROTEIN TIS11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="2"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="37"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="70"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="2"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="37"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="70"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="891"/>
            <end position="932"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1065" mass="125445" checksum="F4399EB47FFCA6FE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW98</accession>
    <name>A0A1J1GW98_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00375900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000060">
        <property type="protein sequence ID" value="CRG96534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529339.1">
        <property type="nucleotide sequence ID" value="XM_028672825.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW98"/>
    <dbReference type="GeneID" id="39732289"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00375900"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="292"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="329" mass="38444" checksum="B37F69D813DFB7FF" modified="2017-02-15" version="1">MALLYNDGCENLKGEIIKCFMRIFPLNSYKFTPIVWSYDFLPVKAENDSNNKLNDLSKNIFKYQRYEPYNHSRIIFLSNNDVDGIMFLFEYNALSYKYPSKTYLCRLRKISQKATICEHIDASYLGKTLSFNSYDVINGKDNIINIKRSKNSKHTVTKLKYRDLSFGRNTCHIVKTKYIEENKCMYHLCEVVNGHLSCFNAYYSGRLIFIDDILYSAIEKRKFLYLPGSCLTKDSNFICDPQLCQYNSTQKLTSCEKLEISSIKNVFPSRGILEPAPTYMPISHENRPSSSILLATSLLPFLVMLVFIWCFVYKFLRRRKSKLFINISV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWW8</accession>
    <name>A0A1J1GWW8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00462100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529844.1">
        <property type="nucleotide sequence ID" value="XM_028673386.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733154"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00462100"/>
    <dbReference type="OMA" id="NMCVERP"/>
    <dbReference type="OrthoDB" id="433924at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31804:SF2">
        <property type="entry name" value="CUE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31804">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="1151"/>
            <end position="1222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="386"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1109"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1644"/>
            <end position="1665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
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            <begin position="386"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
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            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
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            <begin position="428"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
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            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
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    </feature>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
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            <begin position="605"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="632"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="662"/>
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    </feature>
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            <end position="1118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1650"/>
            <end position="1665"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1809" mass="209948" checksum="A97FB2ACA1920726" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX84</accession>
    <name>A0A1J1GX84_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00464000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529863.1">
        <property type="nucleotide sequence ID" value="XM_028673407.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX84"/>
    <dbReference type="GeneID" id="39733173"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00464000"/>
    <dbReference type="OMA" id="LYRIEYM"/>
    <dbReference type="OrthoDB" id="390568at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="78" mass="9329" checksum="C1A45EC165CAA91F" modified="2017-02-15" version="1">MEDNKCDNSYSTKNKVTELLKSPYVKYGTSEIFSNASMHFEKPTREENKKYHIEYLKDGTAIYYKRKPGYIKNFFCCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXA5</accession>
    <name>A0A1J1GXA5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Eukaryotic translation initiation factor subunit eIF2A, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00478200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
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            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530006.1">
        <property type="nucleotide sequence ID" value="XM_028673567.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733315"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00478200"/>
    <dbReference type="OMA" id="PMNSINN"/>
    <dbReference type="OrthoDB" id="378109at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
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        <property type="entry name" value="GYF"/>
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    <dbReference type="InterPro" id="IPR035445">
        <property type="entry name" value="GYF-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="TIF2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013979">
        <property type="entry name" value="TIF_beta_prop-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13227">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13227:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08662">
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00444">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55277">
        <property type="entry name" value="GYF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50829">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="1 8" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="GYF" evidence="7">
        <location>
            <begin position="1998"/>
            <end position="2046"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="697"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="796"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1799"/>
            <end position="1819"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="808"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="852"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
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            <end position="987"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1540"/>
            <end position="1550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1551"/>
            <end position="1569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1642"/>
            <end position="1667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1799"/>
            <end position="1817"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2073" mass="244495" checksum="0140ADD136004690" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXJ6</accession>
    <name>A0A1J1GXJ6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome b5, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00454000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the cytochrome b5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529763.1">
        <property type="nucleotide sequence ID" value="XM_028673295.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXJ6"/>
    <dbReference type="GeneID" id="39733073"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00454000"/>
    <dbReference type="OMA" id="SKCCIII"/>
    <dbReference type="OrthoDB" id="260519at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050668">
        <property type="entry name" value="Cytochrome_b5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19359">
        <property type="entry name" value="CYTOCHROME B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19359:SF25">
        <property type="entry name" value="CYTOCHROME B5 HEME-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="6">
        <location>
            <begin position="6"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="151" mass="17739" checksum="1ED6C849BFB83A53" modified="2017-02-15" version="1">MVEQKLKVIDENDLKNFKNESKCCIIINDLVYDVSSFYEHPGGFDLFKEYEGIDATASFNEIGHSTYAKKLMKSYLIGVKKDTEKYKKKVETKIIENEREYINVSEEEIEEEEDVKTYKPPNVPEEKSNYSILALVIVLFSIAYYFMFIRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXT2</accession>
    <name>A0A1J1GXT2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH OST-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00302800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528624.1">
        <property type="nucleotide sequence ID" value="XM_028672030.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXT2"/>
    <dbReference type="GeneID" id="39731561"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00302800"/>
    <dbReference type="OrthoDB" id="382692at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.610">
        <property type="entry name" value="LOTUS domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056022">
        <property type="entry name" value="DUF7602"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041966">
        <property type="entry name" value="LOTUS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025677">
        <property type="entry name" value="OST-HTH-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025605">
        <property type="entry name" value="OST-HTH/LOTUS_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24549">
        <property type="entry name" value="DUF7602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14418">
        <property type="entry name" value="OHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51644">
        <property type="entry name" value="HTH_OST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH OST-type" evidence="1">
        <location>
            <begin position="816"/>
            <end position="891"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1005" mass="121609" checksum="5F53A362C8A073FC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXV1</accession>
    <name>A0A1J1GXV1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Vacuolar protein sorting-associated protein 54 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00466900</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
            <location evidence="1">trans-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529891.1">
        <property type="nucleotide sequence ID" value="XM_028673439.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733202"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00466900"/>
    <dbReference type="OMA" id="ICKSHWY"/>
    <dbReference type="OrthoDB" id="10259024at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000938">
        <property type="term" value="C:GARP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006896">
        <property type="term" value="P:Golgi to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039745">
        <property type="entry name" value="Vps54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012501">
        <property type="entry name" value="Vps54_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12965">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING 54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12965:SF0">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07928">
        <property type="entry name" value="Vps54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="583"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="702"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1026"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1086"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar protein sorting-associated protein 54 C-terminal" evidence="9">
        <location>
            <begin position="1017"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="508"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG97088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1509" mass="184700" checksum="6366FF4DAE1DB2EB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY46</accession>
    <name>A0A1J1GY46_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Golgi re-assembly stacking protein 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00476300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529987.1">
        <property type="nucleotide sequence ID" value="XM_028673546.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY46"/>
    <dbReference type="GeneID" id="39733296"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00476300"/>
    <dbReference type="OMA" id="KESNIHY"/>
    <dbReference type="OrthoDB" id="3318at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007583">
        <property type="entry name" value="GRASP55_65"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024958">
        <property type="entry name" value="GRASP_PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12893">
        <property type="entry name" value="GOLGI REASSEMBLY STACKING PROTEIN GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12893:SF0">
        <property type="entry name" value="GRASP65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04495">
        <property type="entry name" value="GRASP55_65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51865">
        <property type="entry name" value="PDZ_GRASP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PDZ GRASP-type" evidence="5">
        <location>
            <begin position="11"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ GRASP-type" evidence="5">
        <location>
            <begin position="109"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="527" mass="61924" checksum="F05B4F267D9D1D91" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYB6</accession>
    <name>A0A1J1GYB6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Spindle assembly abnormal protein 6 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00512700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530355.1">
        <property type="nucleotide sequence ID" value="XM_028673953.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYB6"/>
    <dbReference type="GeneID" id="39733660"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00512700"/>
    <dbReference type="OMA" id="RQHITFR"/>
    <dbReference type="OrthoDB" id="49058at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10142">
        <property type="entry name" value="HD_SAS6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.210.20">
        <property type="entry name" value="Spindle assembly abnormal protein 6, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032396">
        <property type="entry name" value="SAS-6_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038558">
        <property type="entry name" value="SAS-6_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34230">
        <property type="entry name" value="ASSEMBLY ABNORMAL PROTEIN 6, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34230:SF2">
        <property type="entry name" value="SPINDLE ASSEMBLY ABNORMAL PROTEIN 6 N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16531">
        <property type="entry name" value="SAS-6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Spindle assembly abnormal protein 6 N-terminal" evidence="1">
        <location>
            <begin position="32"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="235" mass="27609" checksum="02216C0E0E67CE6C" modified="2017-02-15" version="1">MNKYDLNNFLCQFDFSSFQELDPSLNGGYTLCYHKEVPFEIRIQELENGPQEMGSLEIITVKILVLGDELNAQSVKIELTNETDLFFHFTQTIDEISFATMQNNQKLMINFSEYLQVLIKMFNSCIKEPQSFLAIFTIKQNRKARLDFIKNMEYKFIELLVCDFNQSSEENIKESITFRYNLIKSKNTIMYKRLQDISTLIKSKNPSLLMQLQKAACRQLELIKNKKCTKNIKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYG6</accession>
    <name>A0A1J1GYG6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Fe-S cluster assembly protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00355400</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the Mrp/NBP35 ATP-binding proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529141.1">
        <property type="nucleotide sequence ID" value="XM_028672605.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYG6"/>
    <dbReference type="GeneID" id="39732084"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00355400"/>
    <dbReference type="OMA" id="YNVKIVW"/>
    <dbReference type="OrthoDB" id="1741334at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140663">
        <property type="term" value="F:ATP-dependent FeS chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02037">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2020.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="entry name" value="Fe-S cluster assembly (FSCA)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010376">
        <property type="entry name" value="GBBH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038492">
        <property type="entry name" value="GBBH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002744">
        <property type="entry name" value="MIP18-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019591">
        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044304">
        <property type="entry name" value="NUBPL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42961">
        <property type="entry name" value="IRON-SULFUR PROTEIN NUBPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42961:SF2">
        <property type="entry name" value="IRON-SULFUR PROTEIN NUBPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01883">
        <property type="entry name" value="FeS_assembly_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06155">
        <property type="entry name" value="GBBH-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="Fe-S cluster assembly (FSCA) domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MIP18 family-like" evidence="7">
        <location>
            <begin position="24"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="Gamma-butyrobetaine hydroxylase-like N-terminal" evidence="8">
        <location>
            <begin position="535"/>
            <end position="594"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF06155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG96336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="620" mass="73114" checksum="D8D84C85C6528999" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYM6</accession>
    <name>A0A1J1GYM6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00524400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530469.1">
        <property type="nucleotide sequence ID" value="XM_028674080.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYM6"/>
    <dbReference type="GeneID" id="39733777"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00524400"/>
    <dbReference type="OrthoDB" id="376143at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="433"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1019" mass="123998" checksum="0C083074508C1CA3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYX5</accession>
    <name>A0A1J1GYX5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Secreted ookinete protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00533400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530557.1">
        <property type="nucleotide sequence ID" value="XM_028674178.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYX5"/>
    <dbReference type="GeneID" id="39733867"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00533400"/>
    <dbReference type="OMA" id="AICINNG"/>
    <dbReference type="OrthoDB" id="347083at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058332">
        <property type="entry name" value="DUF8019"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42535:SF2">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_146, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42535">
        <property type="entry name" value="OOKINETE PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26058">
        <property type="entry name" value="DUF8019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13385">
        <property type="entry name" value="Laminin_G_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012768901" evidence="1">
        <location>
            <begin position="26"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="DUF8019" evidence="2">
        <location>
            <begin position="283"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="351" mass="39506" checksum="CC2A2EF12B91702B" modified="2017-02-15" version="1">MILFISKILHSLLLLLLFFKERIKCDTNNLSFPECDVSIDSAICINNGQKILLPESKPYGISAHISFDSIHPVDSSGNRNHAIGKFFASTGFGGIGNSSLFRKNYIYINHSDEYFKSVDFSYTFFIYLLEDDISLKNNMDEKFCPIIHKGIIKDKIQESSPAILINAKNGRIKIVLSTSSSINSAGEEFLSNFKLRHHQWYHIAVVRHINHVRLFVDGILDSSFLTEGITKTNDFPIYIGGAPYSIDVCDFPFLLDELKIYNISIGVDQIQSEASATLNGLEPSFVYFGCYHCDINSAILSCPNNYHLCNKVELFIGVYNIMRKFSLNINNIILPFSPENHVGIGICCADI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ70</accession>
    <name>A0A1J1GZ70_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Apical rhoptry neck protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ARNP</name>
        <name evidence="4" type="ORF">PGAL8A_00032900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530691.1">
        <property type="nucleotide sequence ID" value="XM_028674327.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ70"/>
    <dbReference type="GeneID" id="39728852"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00032900"/>
    <dbReference type="OMA" id="ININYCL"/>
    <dbReference type="OrthoDB" id="372826at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009618948" evidence="3">
        <location>
            <begin position="20"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="134"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="57"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="161" mass="19314" checksum="5BE4EA1C2B2DA27E" modified="2017-02-15" version="1">MKKIYLLLILLINLKLKNCFRKNIKKNSLKNSIGDLSSEKRENVLINDLKHLNKEKKDILKININSLNNEEKKKEKKNNDYSFLSLKIIPFILTSLLHTGVNQIPRDNEIHHYAFEKSPIIRYMLRLEERKNSFLYIFFIVISFLVVIIIAFFIFKYFFNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ74</accession>
    <name>A0A1J1GZ74_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DOC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00532200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the APC10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530545.1">
        <property type="nucleotide sequence ID" value="XM_028674164.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ74"/>
    <dbReference type="GeneID" id="39733855"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00532200"/>
    <dbReference type="OMA" id="IYCRCLQ"/>
    <dbReference type="OrthoDB" id="24948at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070979">
        <property type="term" value="P:protein K11-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08366">
        <property type="entry name" value="APC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.260:FF:000132">
        <property type="entry name" value="Anaphase promoting complex subunit 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016901">
        <property type="entry name" value="APC10/Doc1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004939">
        <property type="entry name" value="APC_su10/DOC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12936">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12936:SF0">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03256">
        <property type="entry name" value="ANAPC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01337">
        <property type="entry name" value="APC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51284">
        <property type="entry name" value="DOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="DOC" evidence="6">
        <location>
            <begin position="100"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="293" mass="35380" checksum="C9123BC617C15464" modified="2017-02-15" version="1">MYKNKYELRGNSEFFYENEYENEHNDEYSIESEDWHEDEKDNYDDNYLEENYDESENEEIFNTLNSNYKNKIKRRYNNNSLLNLIGELNVLTNEMPSNWTNDEKIMKKKKKLPKINLDKKYIEVGCLGFWKSSSSKNKFDLTNLKDNNVNTYWQSSSLAPHTITIHFIKLTKISKIYLLFNYLLDESYTPYEISIKIGNDENHLEFLYSTFCDIHKYSLNNPFWFIIDVKNITPLSYLYNYNTNFFKNNDFIYCRCLQIIILSSQHNGKDTRIRQIKIFGPNYSLYKYDKMLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZB1</accession>
    <name>A0A1J1GZB1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">COG complex component COG2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00357900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529160.1">
        <property type="nucleotide sequence ID" value="XM_028672626.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZB1"/>
    <dbReference type="GeneID" id="39732109"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00357900"/>
    <dbReference type="OMA" id="NNFYWLK"/>
    <dbReference type="OrthoDB" id="332281at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009316">
        <property type="entry name" value="COG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024603">
        <property type="entry name" value="COG_complex_COG2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12961">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12961:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12022">
        <property type="entry name" value="COG2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="COG complex component COG2 C-terminal" evidence="2">
        <location>
            <begin position="775"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="122"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="721"/>
            <end position="774"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="962" mass="115199" checksum="2C6EC6EDB68D559B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZD4</accession>
    <name>A0A1J1GZD4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Aquaglyceroporin, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">AQP</name>
        <name evidence="9" type="ORF">PGAL8A_00360300</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529184.1">
        <property type="nucleotide sequence ID" value="XM_028672653.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZD4"/>
    <dbReference type="GeneID" id="39732133"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00360300"/>
    <dbReference type="OMA" id="ITFAVFR"/>
    <dbReference type="OrthoDB" id="3222at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015254">
        <property type="term" value="F:glycerol channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015250">
        <property type="term" value="F:water channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050363">
        <property type="entry name" value="MIP/Aquaporin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829">
        <property type="entry name" value="AQUAPORIN OR AQUAGLYCEROPORIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43829:SF9">
        <property type="entry name" value="AQUAPORIN-9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="131"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG96379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="258" mass="28297" checksum="8BE005A873980474" modified="2017-02-15" version="1">MQLQPYKIPLKEFLGEFLGTFVLMFFGEGSTANYYTAGASNDWLKLCLGWSLGVFFGVLVSAKLSGAHLNLAVSIGLSSIKKFDAKKVPIYFLGQIIGALLGTFSVYRLFYGFVHAEQIPKYVWETGRNKLISLQCAFMNELLLTGLLLLVILVVTDESICGKFHVLKVSTVVGLTILCIGISFGGNTGFALNPSRDLGARLFSLMAYGGQAFSGDHFYFWIPLIAPILGGVIFCQFYDKIICPLLDIPSSEKDVIDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZI6</accession>
    <name>A0A1J1GZI6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EamA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00366000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529240.1">
        <property type="nucleotide sequence ID" value="XM_028672715.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZI6"/>
    <dbReference type="GeneID" id="39732190"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00366000"/>
    <dbReference type="OMA" id="YLLLMNH"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039632">
        <property type="entry name" value="TMEM42"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31965">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31965:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="143" mass="16982" checksum="6F0EE415F1C99073" modified="2017-02-15" version="1">MKDKKYIYMIYNSNIINSFISSICGTLGSVFFKKAFDISLLKSSFGVINKDLILQILLRIIYFLFFLFFNILMIKYYLLLMKQYSAFFSTVLNFSFNFFLSALFGIIFFNEKRNFFWLIGSILIMSGLILILKDTEYEEKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZM9</accession>
    <name>A0A1J1GZM9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ER membrane protein complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">EMC1</name>
        <name evidence="13" type="ORF">PGAL8A_00524900</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EMC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530474.1">
        <property type="nucleotide sequence ID" value="XM_028674085.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZM9"/>
    <dbReference type="GeneID" id="39733782"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00524900"/>
    <dbReference type="OrthoDB" id="28092at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072546">
        <property type="term" value="C:EMC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026895">
        <property type="entry name" value="EMC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011678">
        <property type="entry name" value="EMC1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21573">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21573:SF0">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07774">
        <property type="entry name" value="EMC1_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0732">Signal</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012746337" description="ER membrane protein complex subunit 1" evidence="11">
        <location>
            <begin position="19"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1013"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="domain" description="ER membrane protein complex subunit 1 C-terminal" evidence="12">
        <location>
            <begin position="853"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="domain" description="ER membrane protein complex subunit 1 C-terminal" evidence="12">
        <location>
            <begin position="961"/>
            <end position="1045"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG97673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1046" mass="124029" checksum="D9FC2D02D8B3C30D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H008</accession>
    <name>A0A1J1H008_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00046700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530833.1">
        <property type="nucleotide sequence ID" value="XM_028674485.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H008"/>
    <dbReference type="GeneID" id="39728992"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00046700"/>
    <dbReference type="OMA" id="KNKFFNC"/>
    <dbReference type="OrthoDB" id="372124at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="338"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="575" mass="70065" checksum="10E9630DB5881D80" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H037</accession>
    <name>A0A1J1H037_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mitochondrial import inner membrane translocase subunit TIM16, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00034900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530712.1">
        <property type="nucleotide sequence ID" value="XM_028674350.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H037"/>
    <dbReference type="GeneID" id="39728873"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00034900"/>
    <dbReference type="OMA" id="TCMNVEE"/>
    <dbReference type="OrthoDB" id="10262892at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000090">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit TIM16, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013221416" evidence="1">
        <location>
            <begin position="24"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="124" mass="14560" checksum="42DD2F36B637A400" modified="2017-02-15" version="1">MLPFRPLSQFVFQFLIVTSTALSKAFIQAYKEIIKNKKNTNFIKEKYNTCMNVEEALNILNLDKNKIYKNLNKEELMSLKEEINNRHLILHKLNEKSGPYNGSAYIQKKAKVAKDILFQHLKLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H090</accession>
    <name>A0A1J1H090_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Structural maintenance of chromosomes protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PGAL8A_00030200</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SMC family. SMC4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530666.1">
        <property type="nucleotide sequence ID" value="XM_028674299.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728825"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00030200"/>
    <dbReference type="OMA" id="CPALDNM"/>
    <dbReference type="OrthoDB" id="5575062at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000481">
        <property type="entry name" value="Structural maintenance of chromosomes 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1060.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024704">
        <property type="entry name" value="SMC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010935">
        <property type="entry name" value="SMC_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
        <property type="entry name" value="SMC_hinge_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937:SF172">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18937">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06470">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005719">
        <property type="entry name" value="SMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00968">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75553">
        <property type="entry name" value="Smc hinge domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="7 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC hinge" evidence="14">
        <location>
            <begin position="602"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1063"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="252"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="322"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="429"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="538"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1084"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="1094"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1151"/>
            <end position="1178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR005719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG97867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1475" mass="174851" checksum="D268ADB820D72F99" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0S1</accession>
    <name>A0A1J1H0S1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CSC1/OSCA1-like 7TM region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00471100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529933.1">
        <property type="nucleotide sequence ID" value="XM_028673485.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0S1"/>
    <dbReference type="GeneID" id="39733244"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00471100"/>
    <dbReference type="OMA" id="FFAICVC"/>
    <dbReference type="OrthoDB" id="365492at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005227">
        <property type="term" value="F:calcium-activated cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045122">
        <property type="entry name" value="Csc1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003864">
        <property type="entry name" value="CSC1/OSCA1-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027815">
        <property type="entry name" value="CSC1/OSCA1-like_cyt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018:SF114">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018">
        <property type="entry name" value="PROBABLE MEMBRANE PROTEIN DUF221-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14703">
        <property type="entry name" value="PHM7_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02714">
        <property type="entry name" value="RSN1_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="673"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="718"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="761"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="869"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="924"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="954"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like cytosolic" evidence="3">
        <location>
            <begin position="562"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like 7TM region" evidence="2">
        <location>
            <begin position="679"/>
            <end position="940"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1019" mass="120262" checksum="5C2E6A462D39FDFE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1M0</accession>
    <name>A0A1J1H1M0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cyclin, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">CYC4</name>
        <name evidence="3" type="ORF">PGAL8A_00500700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530236.1">
        <property type="nucleotide sequence ID" value="XM_028673822.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1M0"/>
    <dbReference type="GeneID" id="39733540"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00500700"/>
    <dbReference type="OMA" id="WEDVWSV"/>
    <dbReference type="OrthoDB" id="10264655at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20532">
        <property type="entry name" value="CYCLIN_CCNL_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20533">
        <property type="entry name" value="CYCLIN_CCNL_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036580">
        <property type="entry name" value="Cyclin_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0195">Cyclin</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="2">
        <location>
            <begin position="36"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="2">
        <location>
            <begin position="174"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="275" mass="32789" checksum="7E65D2A215B69B16" modified="2017-02-15" version="1">MINDIILIDKEKVKTPSEEKNIEKNTEIKLRIYGCQLIQEAGIILKLKPVTIATSQVLFHRFYFKKSLTDFDVKIIAPSSLYLSCKLEEDFHRVYKIINTFYFLYKYEDLKSKHYYFDVKNIKIEHFKIDIESQEYKNMKVDIYTYELLILKEIGFLVYKINQHPHLFILPYIHSLFSNLNKYDKDLTKKLAQISWGFLNDSMRTTLCCEYQPRCIAVASIFLAAYNLNIPLIKETNWFKLFDVDYSDIKQICIKILQLYKIGRCEYIDVLAKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H232</accession>
    <name>A0A1J1H232_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein phosphatase PP2A regulatory subunit A, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00516000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530388.1">
        <property type="nucleotide sequence ID" value="XM_028673991.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H232"/>
    <dbReference type="GeneID" id="39733693"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00516000"/>
    <dbReference type="OMA" id="ICNDESW"/>
    <dbReference type="OrthoDB" id="340346at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051023">
        <property type="entry name" value="PP2A_Regulatory_Subunit_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10648:SF4">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2 (FORMERLY 2A), REGULATORY SUBUNIT A, BETA ISOFORM-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10648">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="210"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="210"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="247"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="785" mass="92701" checksum="ECBC507A6928025D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2Q2</accession>
    <name>A0A1J1H2Q2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10">Ribulose-phosphate 3-epimerase</fullName>
            <ecNumber evidence="7 10">5.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PGAL8A_00534100</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>D-ribulose 5-phosphate = D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13677"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="EC" id="5.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="12">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 10">Belongs to the ribulose-phosphate 3-epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.1" evidence="7 10"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530564.1">
        <property type="nucleotide sequence ID" value="XM_028674185.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2Q2"/>
    <dbReference type="GeneID" id="39733874"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00534100"/>
    <dbReference type="OMA" id="SDTVHKC"/>
    <dbReference type="OrthoDB" id="1927044at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004750">
        <property type="term" value="F:D-ribulose-phosphate 3-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00429">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000004">
        <property type="entry name" value="Ribulose-phosphate 3-epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026019">
        <property type="entry name" value="Ribul_P_3_epim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000056">
        <property type="entry name" value="Ribul_P_3_epim-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004076">
        <property type="entry name" value="PRK05581.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11749">
        <property type="entry name" value="RIBULOSE-5-PHOSPHATE-3-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00834">
        <property type="entry name" value="Ribul_P_3_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001461">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01085">
        <property type="entry name" value="RIBUL_P_3_EPIMER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01086">
        <property type="entry name" value="RIBUL_P_3_EPIMER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="12" id="KW-0170">Cobalt</keyword>
    <keyword evidence="9 10 14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-0464">Manganese</keyword>
    <keyword evidence="8 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="38"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="150"/>
            <end position="153"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="201"/>
            <end position="202"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR001461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG97763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="227" mass="25614" checksum="B04C17282171520A" modified="2017-02-15" version="1">MCKLKAIIAPSVLASNISKLAEETQRMETLGAEWIHLDVMDMHFVPNLSFGPPVINNLKKYTNKIFFDVHLMVENPEKYVELLKTSNQITFHFESLNEDIKKCIELAKEIRNNNLWCGISIKPKTDVEKIVPLLDTNLINTVLIMTVEPGFGGQSFMHDMMSKVSFLRKKYPNLNIEVDGGLNIETTEIAASHGANIIVAGTSIFNASNPKFVIDTMRNSVQKYLQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2T2</accession>
    <name>A0A1J1H2T2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00523000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530455.1">
        <property type="nucleotide sequence ID" value="XM_028674064.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2T2"/>
    <dbReference type="GeneID" id="39733763"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00523000"/>
    <dbReference type="OrthoDB" id="347712at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="307"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="517" mass="60946" checksum="743045B03DECD39A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H4C5</accession>
    <name>A0A1J1H4C5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Programmed cell death protein 2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00063300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530991.1">
        <property type="nucleotide sequence ID" value="XM_028674661.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H4C5"/>
    <dbReference type="GeneID" id="39729158"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00063300"/>
    <dbReference type="OMA" id="CGDQVKC"/>
    <dbReference type="OrthoDB" id="443682at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007320">
        <property type="entry name" value="PDCD2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12298">
        <property type="entry name" value="PCDC2 PROGRAMMED CELL DEATH PROTEIN 2 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12298:SF4">
        <property type="entry name" value="PROGRAMMED CELL DEATH PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04194">
        <property type="entry name" value="PDCD2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Programmed cell death protein 2 C-terminal" evidence="2">
        <location>
            <begin position="331"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="474" mass="56058" checksum="904C7B9A76CBCCDC" modified="2017-02-15" version="1">MVHVLLGYLDEKNKKNELKEKNKINKKFISKIGGKPFWLDRINLPNEKSFHCTLCSKLMSFLLQIYAPLDNISKCFHRCLYLFVCLNCGDQVKCFRTQLPRSNLFYNYYLENINHTDNESNSSNELNESIEVCKLDESDESNSSNESIESIEVCKLDESNKSNKSNKCNENKEISSDYINLYENSNNTFNKKLEYYFCCNICGIPSINTKKHKFCELKNHVIFKEKKIYISDEDDCESSSTGNESFSEEYEETYINENYKDLYKENNNENEKNKNINENDKDDSLINDNKKYMNDDDIKNIENKDDNDLDISEMKAFEDIQKDMENQRKIDHVFKNYIKKIQRFPKQIIRYSYNGTPLYSSCDNYNYNQNNFCEEVGKIKHFNTNKNKIPNCHVCGGRMIFEFQVLSTIINYLKIKKNISFNKNITLNSKFSIIAIYTCENNCDMYDINDINLKKKKSKINRYVQEYAYVQIEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2012-07-11" modified="2026-01-28" version="45" xmlns="https://uniprot.org/uniprot">
    <accession>I2FKC6</accession>
    <name>I2FKC6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Aconitate hydratase</fullName>
            <shortName evidence="9">Aconitase</shortName>
            <ecNumber evidence="3 9">4.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ACO</name>
        <name evidence="13" type="ORF">PGAL8A_00253200</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2012" name="Gene" volume="502" first="36" last="39">
            <title>Age of the last common ancestor of extant Plasmodium parasite lineages.</title>
            <authorList>
                <person name="Hayakawa T."/>
                <person name="Tachibana S."/>
                <person name="Hikosaka K."/>
                <person name="Arisue N."/>
                <person name="Matsui A."/>
                <person name="Horii T."/>
                <person name="Tanabe K."/>
            </authorList>
            <dbReference type="PubMed" id="22555021"/>
            <dbReference type="DOI" id="10.1016/j.gene.2012.04.037"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="13 14" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>citrate = D-threo-isocitrate</text>
            <dbReference type="Rhea" id="RHEA:10336"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="EC" id="4.2.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.3" evidence="3 9"/>
    <dbReference type="EMBL" id="AB571135">
        <property type="protein sequence ID" value="BAM15611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="I2FKC6"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00253200"/>
    <dbReference type="OMA" id="NGGIMQY"/>
    <dbReference type="OrthoDB" id="2279155at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003994">
        <property type="term" value="F:aconitate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072350">
        <property type="term" value="P:tricarboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01586">
        <property type="entry name" value="AcnA_IRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01580">
        <property type="entry name" value="AcnA_IRP_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.19.10:FF:000001">
        <property type="entry name" value="Aconitate hydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.499.10:FF:000002">
        <property type="entry name" value="Aconitate hydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.499.10:FF:000014">
        <property type="entry name" value="Aconitate hydratase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="entry name" value="Aconitase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="entry name" value="Aconitase, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044137">
        <property type="entry name" value="AcnA_IRP_Swivel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006249">
        <property type="entry name" value="Aconitase/IRP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01341">
        <property type="entry name" value="aconitase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006757">
        <property type="entry name" value="PRK09277.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009520">
        <property type="entry name" value="PRK12881.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11670">
        <property type="entry name" value="ACONITASE/IRON-RESPONSIVE ELEMENT FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="Aconitase iron-sulfur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52016">
        <property type="entry name" value="LeuD/IlvD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5 9" id="KW-0408">Iron</keyword>
    <keyword evidence="6 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7 9 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha" evidence="10">
        <location>
            <begin position="81"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase A/isopropylmalate dehydratase small subunit swivel" evidence="11">
        <location>
            <begin position="705"/>
            <end position="831"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAM15611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG95127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="909" mass="102652" checksum="A43301D85D0FE09D" modified="2012-07-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKW6</accession>
    <name>A0A1J1GKW6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00072100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525839.1">
        <property type="nucleotide sequence ID" value="XM_028674812.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKW6"/>
    <dbReference type="GeneID" id="39729246"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00072100"/>
    <dbReference type="OMA" id="EQFLDME"/>
    <dbReference type="OrthoDB" id="3219396at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="380" mass="46128" checksum="7A0912A4C22ED3B8" modified="2017-02-15" version="1">MNEFSSDIIKEILKFLTYRDVIKNKYLINKEFYYALNYNDLWKYFYKYEYYEDSINRKRNDPFKELFYIRCIEKKKNKYIDLPKSAQEQFLDMEASLLSLKDCSLNSFNNYDLYNDNSNNWYNNFNNSLNIFHLNYNTNIQLKRHSLSYKNTCKTEEKISSINEVSNLESVIKKKNENNLNMKIRLTYENVSNQDKNIHICSFKHCEFQFIQKNNLYICLTSKNFHVCDDKCDLSIFSDIEWGYLVCPISGKMFDYLSHLKSGNTFLRIRNNISSSLKYIWPNINENSFPYYSDEEKNEIEEQDDQEMEQYFEYSNSFFKRKNKKNKFCFISNIKKNNKAYKKIKKKEKSENYKNNLFKKILNSYKNKKKNNTKKIIPKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLE0</accession>
    <name>A0A1J1GLE0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Serine/threonine-protein kinase RIO2</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Serine/threonine-protein kinase rio2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="primary">RIO2</name>
        <name evidence="18" type="ORF">PGAL8A_00093600</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526054.1">
        <property type="nucleotide sequence ID" value="XM_028671954.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLE0"/>
    <dbReference type="GeneID" id="39729460"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00093600"/>
    <dbReference type="OMA" id="CENEESY"/>
    <dbReference type="OrthoDB" id="10258631at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05144">
        <property type="entry name" value="RIO2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000053">
        <property type="entry name" value="Serine/threonine-protein kinase RIO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000052">
        <property type="entry name" value="Serine/threonine-protein kinase RIO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030484">
        <property type="entry name" value="Rio2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015285">
        <property type="entry name" value="RIO2_wHTH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018934">
        <property type="entry name" value="RIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000687">
        <property type="entry name" value="RIO_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018935">
        <property type="entry name" value="RIO_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45852">
        <property type="entry name" value="SER/THR-PROTEIN KINASE RIO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45852:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE RIO2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01163">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09202">
        <property type="entry name" value="Rio2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00090">
        <property type="entry name" value="RIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01245">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 18" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 18" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RIO kinase" evidence="17">
        <location>
            <begin position="64"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="475"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="366"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="477"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="585"/>
            <end position="621"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00068353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00068837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="CRG93232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="720" mass="86194" checksum="D5418A3E5EBEAFB4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLW6</accession>
    <name>A0A1J1GLW6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00102100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526137.1">
        <property type="nucleotide sequence ID" value="XM_028672877.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLW6"/>
    <dbReference type="GeneID" id="39729546"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00102100"/>
    <dbReference type="OrthoDB" id="360402at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="735" mass="87983" checksum="A55C35D88B554FE3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM09</accession>
    <name>A0A1J1GM09_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00097500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="5">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the peptidase T1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526091.1">
        <property type="nucleotide sequence ID" value="XM_028672366.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM09"/>
    <dbReference type="GeneID" id="39729499"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00097500"/>
    <dbReference type="OMA" id="NHYFTYN"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03753">
        <property type="entry name" value="proteasome_alpha_type_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000054">
        <property type="entry name" value="Proteasome subunit alpha type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033812">
        <property type="entry name" value="Proteasome_alpha_type_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003075">
        <property type="entry name" value="PRK03996.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 4 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="6">
        <location>
            <begin position="8"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="256" mass="28364" checksum="E1E150109F22DD99" modified="2017-02-15" version="1">MFSTRSEYDRGVNTFSPEGRLFQVEYALGAIKLGSTAVGICVNDGVILASERRISSALIEKDSVEKLLAIDDHIGCAMSGLMADARTLIDYARVECNHYKFIYNENINIKSCVELISELALDFSNLSDNKRKKIMSRPFGVALLIGGVDKNGPCLWYTEPSGTNTRFLAASIGSAQEGAELLLQENYNKNMSFQEAEILALTVLRQVMEDKLSSTNVEIAAIKKSEKTFYKYNSEDISRIIDILPSPTYPTIDMTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM39</accession>
    <name>A0A1J1GM39_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00100700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526123.1">
        <property type="nucleotide sequence ID" value="XM_028672721.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM39"/>
    <dbReference type="GeneID" id="39729531"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00100700"/>
    <dbReference type="OMA" id="KKIMYKS"/>
    <dbReference type="OrthoDB" id="392568at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013584">
        <property type="entry name" value="RAP"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51286">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RAP" evidence="3">
        <location>
            <begin position="1102"/>
            <end position="1173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="223"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="60"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="224"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1176" mass="141393" checksum="08A8AD8468DD7511" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMK8</accession>
    <name>A0A1J1GMK8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00137500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526492.1">
        <property type="nucleotide sequence ID" value="XM_028674908.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMK8"/>
    <dbReference type="GeneID" id="39729900"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00137500"/>
    <dbReference type="OMA" id="CIFNYMY"/>
    <dbReference type="OrthoDB" id="370252at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="808"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="410"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="410"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="847" mass="102702" checksum="61EC9D267966822B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMU2</accession>
    <name>A0A1J1GMU2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Endonuclease III homolog</fullName>
            <ecNumber evidence="12">3.2.2.-</ecNumber>
            <ecNumber evidence="12">4.2.99.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Bifunctional DNA N-glycosylase/DNA-(apurinic or apyrimidinic site) lyase</fullName>
            <shortName evidence="12">DNA glycosylase/AP lyase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">NTH1</name>
        <name evidence="16" type="ORF">PGAL8A_00143500</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66592"/>
            <dbReference type="Rhea" id="RHEA-COMP:13180"/>
            <dbReference type="Rhea" id="RHEA-COMP:16897"/>
            <dbReference type="Rhea" id="RHEA-COMP:17067"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136412"/>
            <dbReference type="ChEBI" id="CHEBI:157695"/>
            <dbReference type="ChEBI" id="CHEBI:167181"/>
            <dbReference type="EC" id="4.2.99.18"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 12">Belongs to the Nth/MutY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.-" evidence="12"/>
    <dbReference type="EC" id="4.2.99.18" evidence="12"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMU2"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00143500"/>
    <dbReference type="OMA" id="CTLTDYC"/>
    <dbReference type="OrthoDB" id="2099276at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000703">
        <property type="term" value="F:oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006285">
        <property type="term" value="P:base-excision repair, AP site formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.30:FF:000005">
        <property type="entry name" value="Endonuclease III-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="entry name" value="Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03183">
        <property type="entry name" value="Endonuclease_III_Nth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004036">
        <property type="entry name" value="Endonuclease-III-like_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000445">
        <property type="entry name" value="HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030841">
        <property type="entry name" value="NTH1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43286">
        <property type="entry name" value="ENDONUCLEASE III-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43286:SF1">
        <property type="entry name" value="ENDONUCLEASE III-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00633">
        <property type="entry name" value="HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01155">
        <property type="entry name" value="ENDONUCLEASE_III_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4 12" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8 12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="16" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="10 12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="16" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012498244" description="Endonuclease III homolog" evidence="13">
        <location>
            <begin position="16"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="HhH-GPD" evidence="15">
        <location>
            <begin position="206"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="Helix-hairpin-helix DNA-binding motif class 1" evidence="14">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="CRG93729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="384" mass="45249" checksum="80C9F311980BBA9C" modified="2017-02-15" version="1">MKLLCFFKRLFLVNLYFIKMEKPSKYFSKNKIKKIRVKYEEIPNNTISNVKKLQLEKNMENYQVKDEIMKSNIKGDNSLMNMMKLNKNNEIIQDNHVKNSEQVQSKKPLSKIRVKKEYGVKRKMSKSEINNENNKNILLKNIEKDENMNNYDINLKKEHFLFTYNKIKEMRKNIIAPVDKYGCNKLSEKTDDLKVYRFQTLISCLLSSRTKDEVTAMVMDKLKKHGLTVENILNTSEEYLKKLIYGIGFYNVKAKQIIQICHILKNKYNSDIPNNYEELKKLPGVGEKIAQLILQAALDKHEGIAVDIHVHRIANRLNWVNTKNELNTQKNLKNYVQKDLWSEINTLLVGFGQVICKGKKPICEKCTLTNYCQYYKENLIKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMV9</accession>
    <name>A0A1J1GMV9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00148000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526596.1">
        <property type="nucleotide sequence ID" value="XM_028675024.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMV9"/>
    <dbReference type="GeneID" id="39730004"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00148000"/>
    <dbReference type="OMA" id="FYIYNNE"/>
    <dbReference type="OrthoDB" id="370755at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="734" mass="90250" checksum="63DCD9D2348E1DD5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN58</accession>
    <name>A0A1J1GN58_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00160300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the peptidase T1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526716.1">
        <property type="nucleotide sequence ID" value="XM_028675157.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN58"/>
    <dbReference type="GeneID" id="39730128"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00160300"/>
    <dbReference type="OMA" id="ICMLDHH"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03755">
        <property type="entry name" value="proteasome_alpha_type_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000004">
        <property type="entry name" value="Proteasome subunit alpha type-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003075">
        <property type="entry name" value="PRK03996.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 3 4" id="KW-0647">Proteasome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="5">
        <location>
            <begin position="3"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="241" mass="27217" checksum="4FBFBC8DD194CD0F" modified="2017-02-15" version="1">MTYDRAITVFSPDGHLLQVEHALEAVKKGGCAVAIKSSNFAVLAVEKKNIPKLQNPKTTEKLIKLDEHNCLAFAGLNADARVLINKTRLECQRYYLNMDEPAPVDYIAKYVAKVQQKFTHRGGVRPFGIATLIVGFKNNKEICIYQTEPSGIYASWKAQAIGKNAKTVQEFLEKNYHENMEQNECILLALKAIFEVVELSSKNVEVALLTEKELCFIDEQQINLLVEVIEQERTKKSSQNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNK9</accession>
    <name>A0A1J1GNK9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Calpain, putative</fullName>
            <ecNumber evidence="8">3.4.22.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00168800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.22.-" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526802.1">
        <property type="nucleotide sequence ID" value="XM_028670007.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730215"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00168800"/>
    <dbReference type="OMA" id="HTKWENS"/>
    <dbReference type="OrthoDB" id="167576at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004198">
        <property type="term" value="F:calcium-dependent cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022683">
        <property type="entry name" value="Calpain_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036213">
        <property type="entry name" value="Calpain_III_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051297">
        <property type="entry name" value="PalB/RIM13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001300">
        <property type="entry name" value="Peptidase_C2_calpain_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46143">
        <property type="entry name" value="CALPAIN-7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46143:SF1">
        <property type="entry name" value="CALPAIN-7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00648">
        <property type="entry name" value="Peptidase_C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00720">
        <property type="entry name" value="calpain_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00230">
        <property type="entry name" value="CysPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49758">
        <property type="entry name" value="Calpain large subunit, middle domain (domain III)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50203">
        <property type="entry name" value="CALPAIN_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 4" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Calpain catalytic" evidence="7">
        <location>
            <begin position="897"/>
            <end position="1551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="63"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="156"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="501"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="679"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="65"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="87"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="167"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="501"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="951"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="1469"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="1489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2051" mass="241779" checksum="0BCCA7749867EAA5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNX8</accession>
    <name>A0A1J1GNX8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 5">Phosphoinositide phospholipase C</fullName>
            <ecNumber evidence="1 5">3.1.4.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PI-PLC</name>
        <name evidence="7" type="ORF">PGAL8A_00389700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33179"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:203600"/>
            <dbReference type="EC" id="3.1.4.11"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.11" evidence="1 5"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527014.1">
        <property type="nucleotide sequence ID" value="XM_028670242.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732427"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00389700"/>
    <dbReference type="OrthoDB" id="269822at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004435">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate phospholipase C activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032065">
        <property type="term" value="P:maintenance of protein location in cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051209">
        <property type="term" value="P:release of sequestered calcium ion into cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00275">
        <property type="entry name" value="C2_PLC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08558">
        <property type="entry name" value="PI-PLCc_eukaryota"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024774">
        <property type="entry name" value="PH_dom-Mcp5-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001192">
        <property type="entry name" value="PI-PLC_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001711">
        <property type="entry name" value="PLipase_C_Pinositol-sp_Y"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336:SF36">
        <property type="entry name" value="1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336">
        <property type="entry name" value="PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12814">
        <property type="entry name" value="Mcp5_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00387">
        <property type="entry name" value="PI-PLC-Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00390">
        <property type="entry name" value="PHPHLIPASEC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00149">
        <property type="entry name" value="PLCYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50008">
        <property type="entry name" value="PIPLC_Y_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="4 5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PI-PLC Y-box" evidence="6">
        <location>
            <begin position="901"/>
            <end position="999"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG94193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1294" mass="153826" checksum="65F6A6514564873C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNY8</accession>
    <name>A0A1J1GNY8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00382900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526946.1">
        <property type="nucleotide sequence ID" value="XM_028670167.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNY8"/>
    <dbReference type="GeneID" id="39732359"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00382900"/>
    <dbReference type="OMA" id="RETIPMV"/>
    <dbReference type="OrthoDB" id="272703at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000443">
        <property type="entry name" value="RNA-binding protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003:SF3">
        <property type="entry name" value="FI21236P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="10"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="162"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="240" mass="29092" checksum="B467D299BD580F07" modified="2017-02-15" version="1">MENNSPSKGCRVYVGNLPWKVTWPVLKTHMKKAGDVIRVDIFEDAQGRSKGCGIVEYATYEEAQEAISSLNDSKLEDRLIFVREDREENAGNYEKRRFSNIRKEKFYDYKRDYRRDDYRRDFRRDDYRRDFRRDDFRRDFRRDYRRDDFRRNDFRRSSKRNCTLIVYNLPPQVTWKELKDLFKKHGRVVRADLKNEENSSKELTGVVIMENEYEAKNAIDALNFCNFDGYILKVNFENSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNZ1</accession>
    <name>A0A1J1GNZ1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Mitochondrial processing peptidase alpha subunit, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00070300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG92999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525821.1">
        <property type="nucleotide sequence ID" value="XM_028673865.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNZ1"/>
    <dbReference type="GeneID" id="39729228"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00070300"/>
    <dbReference type="OMA" id="QFQSCTA"/>
    <dbReference type="OrthoDB" id="10251424at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050361">
        <property type="entry name" value="MPP/UQCRC_Complex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851">
        <property type="entry name" value="METALLOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11851:SF49">
        <property type="entry name" value="MITOCHONDRIAL-PROCESSING PEPTIDASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M16 N-terminal" evidence="3">
        <location>
            <begin position="113"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="4">
        <location>
            <begin position="270"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG92999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="533" mass="61497" checksum="730E10BCB743DB08" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP13</accession>
    <name>A0A1J1GP13_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Secreted ookinete protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00174300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526857.1">
        <property type="nucleotide sequence ID" value="XM_028670068.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP13"/>
    <dbReference type="GeneID" id="39730270"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00174300"/>
    <dbReference type="OrthoDB" id="372937at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012158944" evidence="2">
        <location>
            <begin position="24"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="448"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="577"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="717"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="462"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="474"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="492"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="510"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="583"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="717"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="749"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="774"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="784"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="815"/>
            <end position="844"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="901" mass="105003" checksum="96DBC7C9F0B8D13E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP61</accession>
    <name>A0A1J1GP61_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DnaJ protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00379000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526907.1">
        <property type="nucleotide sequence ID" value="XM_028670124.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP61"/>
    <dbReference type="GeneID" id="39732320"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00379000"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052276">
        <property type="entry name" value="Diphthamide-biosynth_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44240">
        <property type="entry name" value="DNAJ DOMAIN (PROKARYOTIC HEAT SHOCK PROTEIN)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44240:SF10">
        <property type="entry name" value="J DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="419"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1236" mass="149377" checksum="1CFF4830DA237794" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPY6</accession>
    <name>A0A1J1GPY6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tryptophan/threonine-rich plasmodium antigen C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00190700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000027">
        <property type="protein sequence ID" value="CRG94510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527327.1">
        <property type="nucleotide sequence ID" value="XM_028670590.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPY6"/>
    <dbReference type="GeneID" id="39730432"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00190700"/>
    <dbReference type="OMA" id="IMEWITK"/>
    <dbReference type="OrthoDB" id="370547at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022089">
        <property type="entry name" value="Plasmodium-antigen_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12319">
        <property type="entry name" value="TryThrA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="Tryptophan/threonine-rich plasmodium antigen C-terminal" evidence="4">
        <location>
            <begin position="116"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="79"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="11"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="350" mass="44290" checksum="7A27859577534FCC" modified="2017-02-15" version="1">MEPNNIAMNDITKTLISSPNSTAENDRNSPGTQNESFGAFYVYLSLSIILFFAFLQLFSDSIVKKMQEQFCESMMLEGKNEDEVNDKEIEEEMKREENKKEAGCNIKEEWIKNERSKWMRQLENDWKEWMVEIEKEKSNWIIERESEWNEWIKNEEKKWINWNKRMEDVFAHNEWEECMGWGRNEWIKWMEEKWMEFMIGNFKEWIKSSEDFMLNLKNTKWKNWKDKKLIEWLMKDWKQKEDDYWNNWEKKKWKRWILIKERKKWMKWKERIYMEKAEWKNWIELKEEEMNNQEKWWAWIKWKKEKLVYLKNWMKLIEKQWIKEERWKEWMNKRENMNKEKSNGNEINEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ04</accession>
    <name>A0A1J1GQ04_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">E2F-associated phosphoprotein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00408400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527201.1">
        <property type="nucleotide sequence ID" value="XM_028670450.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ04"/>
    <dbReference type="GeneID" id="39732614"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00408400"/>
    <dbReference type="OMA" id="KKYRFCT"/>
    <dbReference type="OrthoDB" id="122464at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019370">
        <property type="entry name" value="E2F-assoc_phosphoprotein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15967">
        <property type="entry name" value="E2F-ASSOCIATED PHOSPHOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15967:SF0">
        <property type="entry name" value="E2F-ASSOCIATED PHOSPHOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10238">
        <property type="entry name" value="Eapp_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="238" mass="28157" checksum="AD6E6AEEAA630FA7" modified="2017-02-15" version="1">MNNVINLLINEIKVIERKENVKDLSKEKGINVAKSFLNENFSDAKVSNFLSDKEKDNKRETKEKKINEGNEEKEDEDINDDDDHISESEKKVLQFYDEKIDDYNEEYVNKKYRFCTKNCDSSLCCCGCFTPVCYQSQRHEHYINQYRSLYAVNVKINEDTLLDEDEINSKNKNSNNLDGKEENNIKKDLNNITTTNKKRREKENSLKYHAVFCINCNNHIAYFEIKEKVFHFFDVLPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ80</accession>
    <name>A0A1J1GQ80_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00116100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526277.1">
        <property type="nucleotide sequence ID" value="XM_028674433.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ80"/>
    <dbReference type="GeneID" id="39729686"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00116100"/>
    <dbReference type="OrthoDB" id="392580at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="70"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="322"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="566"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="94"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="121"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="155"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="173"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="212"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="912" mass="106682" checksum="4FF54BC19E013FD9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ81</accession>
    <name>A0A1J1GQ81_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Plasmodium RESA N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00185500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000024">
        <property type="protein sequence ID" value="CRG94460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527281.1">
        <property type="nucleotide sequence ID" value="XM_028670539.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ81"/>
    <dbReference type="GeneID" id="39730382"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00185500"/>
    <dbReference type="OMA" id="YRAPFMS"/>
    <dbReference type="OrthoDB" id="10506423at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="257" mass="31306" checksum="CDD4AEFDC2FCB7D6" modified="2017-02-15" version="1">MENSKIIYLFYFLIVNNLLTSFLSLGNDIPTDIPSYVKNFLYDFNTYSLSKHLEFINFKYNLTRVILNEYDISSNSKKKMLLNSKNKLRDIINNILKEKNFYLSDNQLKDIIIFISNELRRSKIKRSQEQEIEDIECEKSKAYFYFYRDDKLEQILNNMKHFWSTSELINDKDPMWKNEKWNLWDYNFKSKVYNLKKKDSMFFLLLIQNNTPGKVCHSIYKYLETSWLESYRAPFMSDFYYFVYESLEELKEKKDTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ93</accession>
    <name>A0A1J1GQ93_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Maspardin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00200800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527426.1">
        <property type="nucleotide sequence ID" value="XM_028670700.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ93"/>
    <dbReference type="GeneID" id="39730534"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00200800"/>
    <dbReference type="OMA" id="QNDIFCH"/>
    <dbReference type="OrthoDB" id="10264550at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026151">
        <property type="entry name" value="Maspardin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15913">
        <property type="entry name" value="ACID CLUSTER PROTEIN 33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15913:SF0">
        <property type="entry name" value="MASPARDIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="5">
        <location>
            <begin position="45"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="321"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="416"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="331"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="416"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG94611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="571" mass="67620" checksum="57DD3CF673E2F3DE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQH3</accession>
    <name>A0A1J1GQH3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zinc finger protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00209600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527514.1">
        <property type="nucleotide sequence ID" value="XM_028670797.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730623"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00209600"/>
    <dbReference type="OMA" id="IFFCLNN"/>
    <dbReference type="OrthoDB" id="3838338at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072344">
        <property type="term" value="P:rescue of stalled ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044288">
        <property type="entry name" value="ZNF598/HEL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22938:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE ZNF598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22938">
        <property type="entry name" value="ZINC FINGER PROTEIN 598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RING-type" evidence="2">
        <location>
            <begin position="122"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="614"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="688"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1363"/>
            <end position="1412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1456"/>
            <end position="1486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="161"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1363"/>
            <end position="1382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1395"/>
            <end position="1404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1461"/>
            <end position="1470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1472"/>
            <end position="1486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1537" mass="185131" checksum="E906CEEB02741151" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQM6</accession>
    <name>A0A1J1GQM6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cysteine repeat modular protein 4, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00195900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527379.1">
        <property type="nucleotide sequence ID" value="XM_028670648.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730486"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00195900"/>
    <dbReference type="OMA" id="FIKECHY"/>
    <dbReference type="OrthoDB" id="6515930at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.50.10">
        <property type="entry name" value="Tumor Necrosis Factor Receptor, subunit A, domain 2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056048">
        <property type="entry name" value="CRMPA/B-like_DUF7631"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011641">
        <property type="entry name" value="Tyr-kin_ephrin_A/B_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46967">
        <property type="entry name" value="INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN,N-TERMINAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46967:SF1">
        <property type="entry name" value="KERATIN-ASSOCIATED PROTEIN 16-1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24634">
        <property type="entry name" value="DUF7631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07699">
        <property type="entry name" value="Ephrin_rec_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01411">
        <property type="entry name" value="Ephrin_rec_like"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="4118"/>
            <end position="4140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="4147"/>
            <end position="4170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="4182"/>
            <end position="4200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="4231"/>
            <end position="4252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="4484"/>
            <end position="4510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="4534"/>
            <end position="4553"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="4559"/>
            <end position="4582"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="4594"/>
            <end position="4614"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="4620"/>
            <end position="4639"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine-protein kinase ephrin type A/B receptor-like" evidence="3">
        <location>
            <begin position="3232"/>
            <end position="3270"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine-protein kinase ephrin type A/B receptor-like" evidence="3">
        <location>
            <begin position="3582"/>
            <end position="3627"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7631" evidence="4">
        <location>
            <begin position="3832"/>
            <end position="3880"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="4270"/>
            <end position="4345"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="5105"/>
            <end position="5187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF24634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="5223" mass="616604" checksum="8A9CE299F9960BF2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQN7</accession>
    <name>A0A1J1GQN7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Adaptor complexes medium subunit family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00199900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527417.1">
        <property type="nucleotide sequence ID" value="XM_028670690.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQN7"/>
    <dbReference type="GeneID" id="39730525"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00199900"/>
    <dbReference type="OMA" id="SHVEFRI"/>
    <dbReference type="OrthoDB" id="870at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1170">
        <property type="entry name" value="Mu homology domain, subdomain B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050431">
        <property type="entry name" value="Adaptor_comp_med_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10529">
        <property type="entry name" value="AP COMPLEX SUBUNIT MU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00928">
        <property type="entry name" value="Adap_comp_sub"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MHD" evidence="4">
        <location>
            <begin position="215"/>
            <end position="622"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="623" mass="73498" checksum="B3A8F6EAD53757BC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQP5</accession>
    <name>A0A1J1GQP5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Adenylate kinase isoenzyme 6 homolog</fullName>
            <shortName evidence="7">AK6</shortName>
            <ecNumber evidence="7">2.7.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Dual activity adenylate kinase/ATPase</fullName>
            <shortName evidence="7">AK/ATPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">AKLP1</name>
        <name evidence="8" type="ORF">PGAL8A_00106700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. Involved in the late cytoplasmic maturation steps of the 40S ribosomal particles, specifically 18S rRNA maturation. While NMP activity is not required for ribosome maturation, ATPase activity is. Associates transiently with small ribosomal subunit protein uS11. ATP hydrolysis breaks the interaction with uS11. May temporarily remove uS11 from the ribosome to enable a conformational change of the ribosomal RNA that is needed for the final maturation step of the small ribosomal subunit. Its NMP activity may have a role in nuclear energy homeostasis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 7">
            <text>AMP + ATP = 2 ADP</text>
            <dbReference type="Rhea" id="RHEA:12973"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Interacts with small ribosomal subunit protein uS11. Not a structural component of 43S pre-ribosomes, but transiently interacts with them by binding to uS11.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the adenylate kinase family. AK6 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.3" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526184.1">
        <property type="nucleotide sequence ID" value="XM_028673399.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQP5"/>
    <dbReference type="GeneID" id="39729593"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00106700"/>
    <dbReference type="OMA" id="QTGGMII"/>
    <dbReference type="OrthoDB" id="10251185at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:AMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00039">
        <property type="entry name" value="Adenylate_kinase_AK6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020618">
        <property type="entry name" value="Adenyl_kinase_AK6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12595:SF0">
        <property type="entry name" value="ADENYLATE KINASE ISOENZYME 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12595">
        <property type="entry name" value="POS9-ACTIVATING FACTOR FAP7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13238">
        <property type="entry name" value="AAA_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="2 7" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="NMPbind" evidence="7">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="LID" evidence="7">
        <location>
            <begin position="124"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="187" mass="22329" checksum="9223B02DB984E846" modified="2017-02-15" version="1">MKILPNIIVTGVPGVGKSTLCEELEELINKEIKEIKKNENLKMKHLNLSNIIKEERLYEEYDDELEASIYNEDLVNEKLKKLNIENGGYIIDFHDVNFIEEKELIDHIFLLTIKTSNLYERLEKRNYSEAKIKNNIECEIFQVIKEDILDYYENSNIFDELENNDLEQYEKNLQFIKKWILSYINES</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQX0</accession>
    <name>A0A1J1GQX0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RGS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00205700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527475.1">
        <property type="nucleotide sequence ID" value="XM_028670753.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730584"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00205700"/>
    <dbReference type="OrthoDB" id="378234at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025574">
        <property type="entry name" value="Nucleoporin_FG_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016137">
        <property type="entry name" value="RGS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13634">
        <property type="entry name" value="Nucleoporin_FG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50132">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RGS" evidence="2">
        <location>
            <begin position="2296"/>
            <end position="2356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1951"/>
            <end position="2049"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1951"/>
            <end position="1988"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1989"/>
            <end position="2036"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2037"/>
            <end position="2049"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2647" mass="311961" checksum="6DCC96FC55E58C43" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQZ0</accession>
    <name>A0A1J1GQZ0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RNA-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00116400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526280.1">
        <property type="nucleotide sequence ID" value="XM_028674466.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQZ0"/>
    <dbReference type="GeneID" id="39729689"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00116400"/>
    <dbReference type="OMA" id="HESMGWA"/>
    <dbReference type="OrthoDB" id="410044at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010629">
        <property type="term" value="P:negative regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009967">
        <property type="term" value="P:positive regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd12362">
        <property type="entry name" value="RRM3_CELF1-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000383">
        <property type="entry name" value="Sex lethal, isoform D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15241:SF304">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15241">
        <property type="entry name" value="TRANSFORMER-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="7"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="4">
        <location>
            <begin position="103"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="150"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="286" mass="32616" checksum="08E2536D6152338D" modified="2017-02-15" version="1">MSLTNSTKIFIGSIPKDVTEEELKAEASKYGTITQVYYVPATAQSPRGWAFITYEQRSEAYKAIEALDYKCIFPNSQRPLDVRFASYKYNNPTDIQAANKNIWQKHVTSDGHPYYYNSITGHSQWEKPKEILTTNYTGKSTVASFGPPGANVFVFHLPSHWTDMELYQHFQHFGYVISARIQRDSSGRNKGYGFVSFNNPESALNAIKGMHGFYVSGKHLKVQLKKGEEHYVQMNSPAQPQLTPAQPYSVQQPIIGNHHQPYMTHLMYGGMDSPNQMRYNTYSLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR19</accession>
    <name>A0A1J1GR19_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein BCP1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00235800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BCP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527774.1">
        <property type="nucleotide sequence ID" value="XM_028671085.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR19"/>
    <dbReference type="GeneID" id="39730886"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00235800"/>
    <dbReference type="OMA" id="WSQGIED"/>
    <dbReference type="OrthoDB" id="27543at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025602">
        <property type="entry name" value="BCP1_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13261">
        <property type="entry name" value="BRCA2 AND CDKN1A INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13261:SF0">
        <property type="entry name" value="BRCA2 AND CDKN1A-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13862">
        <property type="entry name" value="BCCIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="189"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="10"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="49"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="96"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="189"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="207"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="520" mass="62501" checksum="A42EC929775AC43D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR70</accession>
    <name>A0A1J1GR70_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Elongation factor Tu</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PGAL8A_00242900</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Apicoplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527844.1">
        <property type="nucleotide sequence ID" value="XM_028671164.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR70"/>
    <dbReference type="GeneID" id="39730957"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00242900"/>
    <dbReference type="OMA" id="EGDKEWG"/>
    <dbReference type="OrthoDB" id="2067at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020011">
        <property type="term" value="C:apicoplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070125">
        <property type="term" value="P:mitochondrial translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01884">
        <property type="entry name" value="EF_Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03697">
        <property type="entry name" value="EFTU_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03707">
        <property type="entry name" value="EFTU_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000001">
        <property type="entry name" value="Elongation factor Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000576">
        <property type="entry name" value="Elongation factor Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041709">
        <property type="entry name" value="EF-Tu_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050055">
        <property type="entry name" value="EF-Tu_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033720">
        <property type="entry name" value="EFTU_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004541">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_bac/org"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00485">
        <property type="entry name" value="EF-Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000766">
        <property type="entry name" value="PRK00049.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009372">
        <property type="entry name" value="PRK12735.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009373">
        <property type="entry name" value="PRK12736.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721:SF22">
        <property type="entry name" value="ELONGATION FACTOR TU, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43721">
        <property type="entry name" value="ELONGATION FACTOR TU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0933">Apicoplast</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 13 15" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="12 13" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0934">Plastid</keyword>
    <keyword evidence="11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="14">
        <location>
            <begin position="103"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG95031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="489" mass="55525" checksum="DBB62DC044DCB65D" modified="2017-02-15" version="1">MLKTKYNFLNVFPKNEKIKYGFNKLNQVLEVNKLNRNTNKCKEVKNIGNNNFNKTINNINNNNNNNLKNVNKLINDIYIEKRDENLFKIFKKNFAIGVFERKKPHMNIGTIGHVDHGKTTLTAAITKVCSNLNRGTYKSYEEIDKTPEEQKRGITINATHVEYETEKRHYSHIDCPGHLDYIKNMITGTSQMDGSILVVSAYDGLMPQTKEHVLLSRQIGIEKMIVYLNKIDMCEDQELVDLVELEIRELLSFHKYDGDNVPFIKGSALKALNDDKSEYGVPSILKLLDACDNYIDEPKRKIDLPFLMSIDDVLQISGKGTVATGRVEQGMLKLNDQVEVLGIKDKTIKTVITGIEMFRKTLDTAQAGDQIGVMLKNVKKNDISRGMVITKITNMKTYKKFESDIYVLKNEEGGRKNPFSSYYRPQAYIRTADVNCAVILNEDTQIANPGDNIKCTIELMYPLALDNGLRFSLREGGKTVASGVITKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR79</accession>
    <name>A0A1J1GR79_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BRO1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00125300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526368.1">
        <property type="nucleotide sequence ID" value="XM_028674770.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR79"/>
    <dbReference type="GeneID" id="39729778"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00125300"/>
    <dbReference type="OrthoDB" id="370520at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09034">
        <property type="entry name" value="BRO1_Alix_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.280">
        <property type="entry name" value="alix/aip1 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004328">
        <property type="entry name" value="BRO1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038499">
        <property type="entry name" value="BRO1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23030">
        <property type="entry name" value="PCD6 INTERACTING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23030:SF30">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03097">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01041">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRO1" evidence="2">
        <location>
            <begin position="13"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="458"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="687"/>
            <end position="725"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="817" mass="98164" checksum="E7319271DF8B0BDA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR85</accession>
    <name>A0A1J1GR85_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thioredoxin, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00242300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PITHD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527838.1">
        <property type="nucleotide sequence ID" value="XM_028671158.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR85"/>
    <dbReference type="GeneID" id="39730951"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00242300"/>
    <dbReference type="OMA" id="RLVFKPW"/>
    <dbReference type="OrthoDB" id="2635at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.470">
        <property type="entry name" value="PITH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045099">
        <property type="entry name" value="PITH1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010400">
        <property type="entry name" value="PITH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037047">
        <property type="entry name" value="PITH_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12175">
        <property type="entry name" value="AD039 HT014 THIOREDOXIN FAMILY TRP26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12175:SF1">
        <property type="entry name" value="PITH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06201">
        <property type="entry name" value="PITH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51532">
        <property type="entry name" value="PITH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PITH" evidence="2">
        <location>
            <begin position="13"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="206" mass="23420" checksum="28F9003A9BD8A76A" modified="2017-02-15" version="1">MTILHNEGCGCKSSDEVLKGGEFLLKYINLEKVTALNEKIHGSCRKILKSYDNRLSVDHCESDVDHELIINIPFTSPCKIVSLFLIGGEEGSYPRKMKIFSNREDIDFENINDFKCIQELELSQDYHGSVEYPLKVTSLFNVNYLTLYFSENYGSESTKIFYIGLKGVGTNYTRKPVETVYEASPNLADHKIEGNVNSTHFSFDAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRJ0</accession>
    <name>A0A1J1GRJ0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L23, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00244000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527855.1">
        <property type="nucleotide sequence ID" value="XM_028671176.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRJ0"/>
    <dbReference type="GeneID" id="39730968"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00244000"/>
    <dbReference type="OMA" id="MIQMQTR"/>
    <dbReference type="OrthoDB" id="407959at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00337">
        <property type="entry name" value="Ribosomal_uL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.150.20:FF:000008">
        <property type="entry name" value="60S ribosomal protein L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.150.20">
        <property type="entry name" value="Ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01367">
        <property type="entry name" value="Ribosomal_uL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000218">
        <property type="entry name" value="Ribosomal_uL14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036853">
        <property type="entry name" value="Ribosomal_uL14_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761">
        <property type="entry name" value="50S/60S RIBOSOMAL PROTEIN L14/L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761:SF8">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00238">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01374">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50193">
        <property type="entry name" value="Ribosomal protein L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="139" mass="14945" checksum="16C48E811C6BA7FB" modified="2017-02-15" version="1">MKRGRAGTLKNKMRITLSLPVGALINCCDNSGGKNLYIIAVQGFGSCLNRLPAASLGDMVLATVKKGKPDLRKKVLNAIIARQSKAWRRHEGYFIYFEDNAGVIVNPKGEMKGSAITGPVARECAELWPKLSSAASAIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRP9</accession>
    <name>A0A1J1GRP9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00167600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526789.1">
        <property type="nucleotide sequence ID" value="XM_028669993.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730202"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00167600"/>
    <dbReference type="OMA" id="CVINNVE"/>
    <dbReference type="OrthoDB" id="372950at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="569"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="612"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1727"/>
            <end position="1823"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="271"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="588"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="612"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="769"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="797"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1732"/>
            <end position="1745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1768"/>
            <end position="1780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1810"/>
            <end position="1823"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1853" mass="216364" checksum="E5D90D9FC7E4BB53" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS36</accession>
    <name>A0A1J1GS36_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 18">Pre-mRNA-processing factor 19</fullName>
            <ecNumber evidence="5 18">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="primary">PRPF19</name>
        <name evidence="21" type="ORF">PGAL8A_00008000</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 18">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="18">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 18">Belongs to the WD repeat PRP19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="5 18"/>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528124.1">
        <property type="nucleotide sequence ID" value="XM_028671475.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS36"/>
    <dbReference type="GeneID" id="39728602"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00008000"/>
    <dbReference type="OMA" id="SLDQHWA"/>
    <dbReference type="OrthoDB" id="687049at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071006">
        <property type="term" value="C:U2-type catalytic step 1 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070534">
        <property type="term" value="P:protein K63-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16656">
        <property type="entry name" value="RING-Ubox_PRP19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000027">
        <property type="entry name" value="Pre-mRNA-processing factor 19, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038959">
        <property type="entry name" value="Prp19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013915">
        <property type="entry name" value="Prp19_cc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055340">
        <property type="entry name" value="RING-Ubox_PRP19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43995">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43995:SF1">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08606">
        <property type="entry name" value="Prp19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="19" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="12 18" id="KW-0227">DNA damage</keyword>
    <keyword evidence="15 18" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 18" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="14 18" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="16 18" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0677">Repeat</keyword>
    <keyword evidence="10 18" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="9 18" id="KW-0808">Transferase</keyword>
    <keyword evidence="13 18" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7 17" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="U-box" evidence="20">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="17">
        <location>
            <begin position="251"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="17">
        <location>
            <begin position="297"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="17">
        <location>
            <begin position="339"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="17">
        <location>
            <begin position="381"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="17">
        <location>
            <begin position="466"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="19">
        <location>
            <begin position="109"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00015618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU367101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="CRG95313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="498" mass="56717" checksum="BE2761B2260D4224" modified="2017-02-15" version="1">MSILCTISGQTPEEPVVSKTGYIFEKRLIEKHIINYGICPVSGELLTLQDLYPIKNEKIVKPRPISASSIPGLLSIFQTEWDSIISEMFSLRTHVNDIRNQLSHSLYQYDAATRVIAKLLKEKNSYKEEIDNLRNQIFQLKSGNDINEFEIGITDDLLNEMQTTAKNLLMKRKKRKIENVCSVDLWKEFKNSNEFNIHSSVVAGVTCLSLDINKYKYNYYDDHSNHNFFSGGKDGNIYYVSLSDNKILSKLQGHLKKINSIVSHPSNFICISGSNDKTIRIWKGDSDTNEYVTSHLIKKHKDNITSLSLHPLENCFISSSKDNTWILHDLETSKTIKICKNNPSSFKNVSIHPDGMMLGVASDDSNIHIYDIKSQEYKASLTGHTKAVECISFSENGYYLASCSKDNTVKLWDLRKALSFQTLELEHTPKHITFDYSGKYLSVSIGNDIQIYNFETKNEVTLIKTLMSHTDAVTQTCFGSRTSYLLSSSMDKTIKLWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSA8</accession>
    <name>A0A1J1GSA8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Elongation factor Tu, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00259300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528001.1">
        <property type="nucleotide sequence ID" value="XM_028671339.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSA8"/>
    <dbReference type="GeneID" id="39731122"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00259300"/>
    <dbReference type="OMA" id="IYICMGG"/>
    <dbReference type="OrthoDB" id="364892at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042256">
        <property type="term" value="P:cytosolic ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04096">
        <property type="entry name" value="eEF2_snRNP_like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF3">
        <property type="entry name" value="ELONGATION FACTOR-LIKE GTPASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="2">
        <location>
            <begin position="11"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="802"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="802"/>
            <end position="817"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1280" mass="150028" checksum="E2EC6C861ACDBF14" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSE6</accession>
    <name>A0A1J1GSE6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PGAL8A_00015200</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the DEAD box helicase family. DECD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528194.1">
        <property type="nucleotide sequence ID" value="XM_028671553.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSE6"/>
    <dbReference type="GeneID" id="39728674"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00015200"/>
    <dbReference type="OMA" id="YAHVEPK"/>
    <dbReference type="OrthoDB" id="10265785at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17950">
        <property type="entry name" value="DEADc_DDX39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000111">
        <property type="entry name" value="DEAD-box ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 14" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="13">
        <location>
            <begin position="59"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="90"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="12">
        <location>
            <begin position="311"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="15"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="9">
        <location>
            <begin position="59"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="30"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG95383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="476" mass="54489" checksum="A02E23F9E4560F61" modified="2017-02-15" version="1">MASIDHSVQDELVDYEDDDNILDNKDTKGSLENNILNDSNKNVNENGAMRGSYATVHTGGFKDFFLKPELLRAISESGFEHPSEVQQETIPAAITGTDILCQAKSGMGKTAVFVLSILQQLDTNENKEIKEEKEINNIRANDNNNINVSDELKSNNKSQNKYVRCLGLAHTRELAYQIKNEFDRFSKYLKNVRCEVVYGGISMSKHIKLFKEENIPHIIIGTPGRILALIREKYLVTDKIQHFVLDECDKCLEKLDMRSDVQKIFISTPLKKQVMFFSATMAKEMRDVCKKFLQNPVEIFIDDEAKLKLHGLLQHYVKLQEKDKTRKLIEILDALEFNQVIIFVKSVTRAITLDKLLTECNFPSIAIHGGLDQQERIERYDKFKKFENRILVSTDLFGRGIDIERVNIVINYDMPENSDSYLHRVGRAGRFGTKGLAITFVSSQEDTLALNEVQTRFEVAISEMPNKIDCNEYINQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSI9</accession>
    <name>A0A1J1GSI9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00020000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528242.1">
        <property type="nucleotide sequence ID" value="XM_028671606.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSI9"/>
    <dbReference type="GeneID" id="39728722"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00020000"/>
    <dbReference type="OMA" id="YMNMRNE"/>
    <dbReference type="OrthoDB" id="376497at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="287"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="392"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="515"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="636" mass="77050" checksum="94C5C49DF9EFC9EF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSJ1</accession>
    <name>A0A1J1GSJ1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Gamete antigen 27/25, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00265200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000034">
        <property type="protein sequence ID" value="CRG95449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528260.1">
        <property type="nucleotide sequence ID" value="XM_028671626.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSJ1"/>
    <dbReference type="GeneID" id="39731181"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00265200"/>
    <dbReference type="OrthoDB" id="387098at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3030.10">
        <property type="entry name" value="Gametocyte protein Pfg27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015299">
        <property type="entry name" value="Gamete_antigen_PLAspp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036469">
        <property type="entry name" value="Pfg27_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09216">
        <property type="entry name" value="Pfg27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89162">
        <property type="entry name" value="Gametocyte protein Pfg27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="207" mass="24028" checksum="E5887564CEA9C17D" modified="2017-02-15" version="1">MAVDEVTENPSLKPGTKPRPCEKYIDNFFRCCDVEFKTTNSMLGKLKECKSNSEMEAKLKDYNAIKEEIVNVGMHECNFLIEKEFHDNMSYRISDRLRDFCFEEKLTDEYIFKVKEIYSAEDKAGADVFFETCNKEGNLERKKVIDDMALIKSNLRKHEQCTHIKLSEEKLNNAAKRVQRLLCDLCLLTLRPAKDLPLKPDDGKPPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSR5</accession>
    <name>A0A1J1GSR5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA-directed primase/polymerase protein</fullName>
            <ecNumber evidence="3">2.7.7.102</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00277100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:22509"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ssDNA + n NTP = ssDNA/pppN(pN)n-1 hybrid + (n-1) diphosphate.</text>
            <dbReference type="EC" id="2.7.7.102"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.102" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528382.1">
        <property type="nucleotide sequence ID" value="XM_028671762.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSR5"/>
    <dbReference type="GeneID" id="39731304"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00277100"/>
    <dbReference type="OMA" id="VSEIYYL"/>
    <dbReference type="OrthoDB" id="5988181at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006264">
        <property type="term" value="P:mitochondrial DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009411">
        <property type="term" value="P:response to UV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044917">
        <property type="entry name" value="PRIMPOL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31399">
        <property type="entry name" value="DNA-DIRECTED PRIMASE / POLYMERASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31399:SF0">
        <property type="entry name" value="DNA-DIRECTED PRIMASE_POLYMERASE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="337"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00026139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00044677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="870" mass="106367" checksum="08CDE8B978FA7F45" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSR9</accession>
    <name>A0A1J1GSR9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00272100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000042">
        <property type="protein sequence ID" value="CRG95521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528330.1">
        <property type="nucleotide sequence ID" value="XM_028671704.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSR9"/>
    <dbReference type="GeneID" id="39731253"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00272100"/>
    <dbReference type="OrthoDB" id="10554499at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="245"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="500"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="563"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="245"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1207" mass="147473" checksum="A244ECB6269DC7EC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSS0</accession>
    <name>A0A1J1GSS0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Choline kinase, putative</fullName>
            <ecNumber evidence="2">2.7.1.32</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">CK</name>
        <name evidence="2" type="ORF">PGAL8A_00273600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the choline/ethanolamine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.32" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528348.1">
        <property type="nucleotide sequence ID" value="XM_028671724.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSS0"/>
    <dbReference type="GeneID" id="39731268"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00273600"/>
    <dbReference type="OMA" id="VEGNTME"/>
    <dbReference type="OrthoDB" id="3649325at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004103">
        <property type="term" value="F:choline kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004305">
        <property type="term" value="F:ethanolamine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14021">
        <property type="entry name" value="ChoK-like_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22603">
        <property type="entry name" value="CHOLINE/ETHANOALAMINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22603:SF93">
        <property type="entry name" value="RE24176P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01633">
        <property type="entry name" value="Choline_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="437" mass="51486" checksum="D50F4D4A74657DDE" modified="2017-02-15" version="1">MEVNINEQIDINKNNSRGIGNNRGNINLVKNGDLCYSQDLKNYTTIQLNNEIEISKNPFPLHEINKKNDIPLCAQEFSDLTDPLHIKKICLEKVHDWNDLTEDDICVNQILCGLTNQLFEVSLKEDLAKKSNLKRKHVLFRIYGKDVQELYNPIYELEVYKTMSKYKIAPLLLNTFNGGRIEEWLYGDPLSTDDLKNPSILVGIANVLGKFHTISRKYPLPIHWEKTPCIYKRMEKWKNQVLKYSDLDKLTYDINKYIKESDKFIKFIKEYTQSDNIANHIVFCHNDLQENNIINTNKCLRLIDFEYSGYNYLSNDIANFFNETTIDYSVSTYPFFTIDKKKYIPYELRKLFVSTYLSAYLGNSYVASDEKVVNLFLDAVEVQALGVHLIWGFWSIIRGYQTKSYNEFDFFLYAKERFNMYDEQKEYLISNNIIKDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSS9</accession>
    <name>A0A1J1GSS9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00381100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526928.1">
        <property type="nucleotide sequence ID" value="XM_028670147.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSS9"/>
    <dbReference type="GeneID" id="39732341"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00381100"/>
    <dbReference type="OrthoDB" id="418962at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="310" mass="38306" checksum="489206576BF67C14" modified="2017-02-15" version="1">MQKVFIKLKNYNILKIEKKYGGTSLLTKIGQSFNQENLKNMKMKLNYEKDPSSTFKSGDTSIFKNFIDIFKRTNIKDKLKMNDNEKQEKKFFEHYMKCLMKYEGIFTYRKFQLFLKDLCDYFNLFSIRYKYKKKINPQLEKLKKQYEVLNSFLPYELDSDDYKIFHNESKKYLAQSCNVDVKFIDELLLFHDSLKTDRTWFYRRILLKRKLPESFEEREIEAPYDRPVTKTFNYNIKESSLEYEEYLNKNSRKLKFKKWYSKKHPWFRKNTSGKDRWRIRPYTKKFPYLYYSRIPKYLYLSKNKPKIKNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSW4</accession>
    <name>A0A1J1GSW4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00411300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000044">
        <property type="protein sequence ID" value="CRG95534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528343.1">
        <property type="nucleotide sequence ID" value="XM_028671718.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSW4"/>
    <dbReference type="GeneID" id="39732643"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00411300"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="110" mass="13913" checksum="C7163F45AB6C03E3" modified="2017-02-15" version="1">MMNFIKENFIQNNVIILEIKKKRSRNAILDIEKVEIEKWKKKKWFIELMLEMKRKEKEYIREVYEDMIAKKNEDKIRNPMLEMQKIIWKKHCEDIHRRWIEKNNKEILQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSW6</accession>
    <name>A0A1J1GSW6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00410700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527221.1">
        <property type="nucleotide sequence ID" value="XM_028670472.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSW6"/>
    <dbReference type="GeneID" id="39732637"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00410700"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="548"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="481"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="771" mass="94155" checksum="E2A2CC299BBD7661" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSX8</accession>
    <name>A0A1J1GSX8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00274800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528359.1">
        <property type="nucleotide sequence ID" value="XM_028671736.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSX8"/>
    <dbReference type="GeneID" id="39731280"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00274800"/>
    <dbReference type="OMA" id="WISEFIY"/>
    <dbReference type="OrthoDB" id="371591at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009290">
        <property type="entry name" value="Radial_spoke_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06098">
        <property type="entry name" value="Radial_spoke_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="447" mass="53620" checksum="E35A08A5EDDC586C" modified="2017-02-15" version="1">MEHNFQIKPIQLKFNKPQENNSNKYINSKKPLKAIKNNEKINDKKENVSSIKVENKKKEYNLFKNVKDIKTNTNDQKVKYNIKNKTNSKHNEFIDLKEEKNKLNYINKYCKNSEKKNEVNKENKKLGKSGIISSIKINNENEKCNDIKNSCKNNIQNTQNSKIYTKVIKYEDNYLNDLLKKENVCIQSVKCDEHNEENEEIMLSNNSTLEESSQEDIYSLDLIEQYKLKKKKELETKRKKIILYKKSKLIKKATFRNAETQVILDDFSKYYEKVKPKIEKIVEDILNKALKELYEEQELKKIKSEIDYYENIRKEKLLSLKKFEKTSEDFYEETQEKIKNRIKLKNKVEMIMKKKIANNKAQKNIHYIFQKNLDLYSLMDLLPNNFEKFINLIIIPWISEFIYYIVNVNKEIVHHIMTDMIEQSIISSSEIYEKFKRLTYIKNKKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSY5</accession>
    <name>A0A1J1GSY5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA-damage inducible protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00280900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DDI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528420.1">
        <property type="nucleotide sequence ID" value="XM_028671804.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSY5"/>
    <dbReference type="GeneID" id="39731342"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00280900"/>
    <dbReference type="OrthoDB" id="1047367at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05479">
        <property type="entry name" value="RP_DDI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019103">
        <property type="entry name" value="Peptidase_aspartic_DDI1-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12917">
        <property type="entry name" value="ASPARTYL PROTEASE DDI-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12917:SF1">
        <property type="entry name" value="AT13091P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09668">
        <property type="entry name" value="Asp_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="6">
        <location>
            <begin position="4"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="Aspartic peptidase DDI1-type" evidence="7">
        <location>
            <begin position="217"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="152"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="368" mass="42654" checksum="2A95F58212FAE2F1" modified="2017-02-15" version="1">MVFITISDDSKIITSLDVLEETEISTIMNIIENDFSISMNINELTYNGNALNKYDTIKKLNIKEGDLLFIRKKLSLDLDLINNNTNNQTTNNNNLNNTNKFSFNTLLEQFKEIQENEYIKKEAENLLHLKNDKSKMCVLEIQDKKLYDAIINGNIEEIKKILKEKYENEKKEKEREQQMYEKALKNPLSEDSQKYIYENIYKNQINSNLALAQEHFPEAFGVVFMLYIPVEINKKVVHAFVDSGAQSSIMSKKCAEKCNILRLMDKRFTGIAKGVGTKTILGKIHMIDIKIGNHFYAVSLTIIDEYDIEFIFGLDLLKRHQCSIDLKQNALIIDNDKIPFLSEKDVISRSSQNIDLDITKDEINDFYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTL1</accession>
    <name>A0A1J1GTL1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">DEAD/DEAH box ATP-dependent RNA helicase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00409100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527208.1">
        <property type="nucleotide sequence ID" value="XM_028670458.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTL1"/>
    <dbReference type="GeneID" id="39732621"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00409100"/>
    <dbReference type="OMA" id="GIGIKCC"/>
    <dbReference type="OrthoDB" id="10261904at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001804">
        <property type="entry name" value="ATP-dependent RNA helicase DDX47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF24">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="9">
        <location>
            <begin position="114"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="145"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="343"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="114"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG94387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="520" mass="60187" checksum="11ECFD3604019ED0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTP8</accession>
    <name>A0A1J1GTP8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">General transcription factor 3C polypeptide 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00311500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528710.1">
        <property type="nucleotide sequence ID" value="XM_028672126.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTP8"/>
    <dbReference type="GeneID" id="39731648"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00311500"/>
    <dbReference type="OMA" id="ANHSDDH"/>
    <dbReference type="OrthoDB" id="5598268at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000127">
        <property type="term" value="C:transcription factor TFIIIC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001002">
        <property type="term" value="F:RNA polymerase III type 1 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001003">
        <property type="term" value="F:RNA polymerase III type 2 promoter sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006384">
        <property type="term" value="P:transcription initiation at RNA polymerase III promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.160">
        <property type="entry name" value="TFIIIC, subcomplex tauA, subunit Sfc1, barrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019136">
        <property type="entry name" value="TF_IIIC_su-5_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040454">
        <property type="entry name" value="TF_IIIC_Tfc1/Sfc1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041499">
        <property type="entry name" value="Tfc1/Sfc1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042536">
        <property type="entry name" value="TFIIIC_tauA_Sfc1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13230:SF5">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13230">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR IIIC, POLYPEPTIDE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09734">
        <property type="entry name" value="Tau95"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17682">
        <property type="entry name" value="Tau95_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="Transcription factor IIIC subunit Tfc1/Sfc1 triple barrel" evidence="6">
        <location>
            <begin position="38"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Transcription factor IIIC subunit 5 HTH" evidence="5">
        <location>
            <begin position="677"/>
            <end position="789"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF09734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1016" mass="119887" checksum="83F957D19E7FAD6F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTR8</accession>
    <name>A0A1J1GTR8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">CWF21 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00209900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527517.1">
        <property type="nucleotide sequence ID" value="XM_028670801.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTR8"/>
    <dbReference type="GeneID" id="39730626"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00209900"/>
    <dbReference type="OMA" id="RNIDANE"/>
    <dbReference type="OrthoDB" id="10267305at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051372">
        <property type="entry name" value="CWC21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013170">
        <property type="entry name" value="mRNA_splic_Cwf21_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36562">
        <property type="entry name" value="SERINE/ARGININE REPETITIVE MATRIX 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36562:SF5">
        <property type="entry name" value="SERINE_ARGININE REPETITIVE MATRIX 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01115">
        <property type="entry name" value="cwf21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="CWF21" evidence="8">
        <location>
            <begin position="60"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="171"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="349"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="483"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="549"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="171"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="184"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="295"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="355"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="377"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="396"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="418"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="444"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="487"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="574"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="610"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="664"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="711"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="880"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="917"/>
            <end position="927"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="927" mass="113381" checksum="187F5EA982E8776A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU47</accession>
    <name>A0A1J1GU47_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transmission-blocking target antigen s230, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00195600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cell surface</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527376.1">
        <property type="nucleotide sequence ID" value="XM_028670645.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU47"/>
    <dbReference type="GeneID" id="39730483"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00195600"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2860">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010884">
        <property type="entry name" value="6_CYS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038160">
        <property type="entry name" value="6_CYS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07422">
        <property type="entry name" value="s48_45"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="s48_45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51701">
        <property type="entry name" value="6_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="6-Cys" evidence="8">
        <location>
            <begin position="157"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="343" mass="40414" checksum="905E63041BFCC159" modified="2017-02-15" version="1">MNKELNIHINGVLFVNETKNNKLDNEETKKKIYIYNNFFFNLNDNYNEYICRIKNFHMFSSCTEIASYNSNLTNDCLTSKNSTNYFYNVLVPFDNSYMNVKITDALQGSIIDYSKNLNNGSSFYLPYYVKEPITCMYKDEKNNTVANYIILKKNEKKILGCDFSDNSESFLSYHFDLQNFKEEILICNIHAKQYDFIGFFCSSKKNSTDYKISPYSCFNYVYDEKMNIQNIDDIIKPINFIPTNQNTNIKNPRYVKISSDKEKKFSCVCTYSNENAIKNGIMIINLSTEETENETLLSKKIYFKENILLTEEPESDDYSSDLFSLNNFEITLPFFIFFLFFIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUB1</accession>
    <name>A0A1J1GUB1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Importin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00303900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528635.1">
        <property type="nucleotide sequence ID" value="XM_028672042.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731572"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00303900"/>
    <dbReference type="OMA" id="EHILCMI"/>
    <dbReference type="OrthoDB" id="361693at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997:SF60">
        <property type="entry name" value="IMPORTIN N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997">
        <property type="entry name" value="IMPORTIN-7, 8, 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1036"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1205"/>
            <end position="1228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1240"/>
            <end position="1258"/>
        </location>
    </feature>
    <feature type="domain" description="Importin N-terminal" evidence="5">
        <location>
            <begin position="28"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1417" mass="169725" checksum="D2CCB6826E4DF8E6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUB3</accession>
    <name>A0A1J1GUB3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phosphodiesterase</fullName>
            <ecNumber evidence="5">3.1.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PDEdelta</name>
        <name evidence="9" type="ORF">PGAL8A_00230000</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="5">Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the cyclic nucleotide phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.-" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527717.1">
        <property type="nucleotide sequence ID" value="XM_028671023.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUB3"/>
    <dbReference type="GeneID" id="39730827"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00230000"/>
    <dbReference type="OMA" id="YIIINQV"/>
    <dbReference type="OrthoDB" id="68317at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004114">
        <property type="term" value="F:3',5'-cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1300.10">
        <property type="entry name" value="3'5'-cyclic nucleotide phosphodiesterase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023088">
        <property type="entry name" value="PDEase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002073">
        <property type="entry name" value="PDEase_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036971">
        <property type="entry name" value="PDEase_catalytic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023174">
        <property type="entry name" value="PDEase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11347">
        <property type="entry name" value="CYCLIC NUCLEOTIDE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00233">
        <property type="entry name" value="PDEase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00387">
        <property type="entry name" value="PDIESTERASE1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00126">
        <property type="entry name" value="PDEASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51845">
        <property type="entry name" value="PDEASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 4 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="PDEase" evidence="8">
        <location>
            <begin position="350"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="783"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="783"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="803"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="429"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="433"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="469"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="470"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="470"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
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        <location>
            <position position="586"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="815" mass="97184" checksum="30D6BAD473F9D51C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUE7</accession>
    <name>A0A1J1GUE7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00337100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528958.1">
        <property type="nucleotide sequence ID" value="XM_028672402.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUE7"/>
    <dbReference type="GeneID" id="39731901"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00337100"/>
    <dbReference type="OrthoDB" id="5973539at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39308">
        <property type="entry name" value="HEAVY PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39308:SF2">
        <property type="entry name" value="HEAVY PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="292"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="315"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="509"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="3">
        <location>
            <begin position="39"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="387"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="403"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="587" mass="69434" checksum="1258BE2319A79762" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUG4</accession>
    <name>A0A1J1GUG4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Dna2/nam7 helicase family member, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00334000</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA2/NAM7 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528930.1">
        <property type="nucleotide sequence ID" value="XM_028672371.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUG4"/>
    <dbReference type="GeneID" id="39731870"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00334000"/>
    <dbReference type="OMA" id="IFCVHGP"/>
    <dbReference type="OrthoDB" id="6513042at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050534">
        <property type="entry name" value="Coronavir_polyprotein_1ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43788:SF8">
        <property type="entry name" value="DNA-BINDING PROTEIN SMUBP-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43788">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="324"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="631"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="430"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="231"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="642"/>
            <end position="652"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG96125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="986" mass="116007" checksum="641A568DCFEE4AAB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUJ9</accession>
    <name>A0A1J1GUJ9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">AATF leucine zipper-containing domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00319000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AATF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528785.1">
        <property type="nucleotide sequence ID" value="XM_028672210.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUJ9"/>
    <dbReference type="GeneID" id="39731723"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00319000"/>
    <dbReference type="OMA" id="YSKKMCL"/>
    <dbReference type="OrthoDB" id="372499at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025160">
        <property type="entry name" value="AATF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039223">
        <property type="entry name" value="AATF/Bfr2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012617">
        <property type="entry name" value="AATF_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15565">
        <property type="entry name" value="AATF PROTEIN APOPTOSIS ANTAGONIZING TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15565:SF0">
        <property type="entry name" value="PROTEIN AATF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13339">
        <property type="entry name" value="AATF-Che1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08164">
        <property type="entry name" value="TRAUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AATF leucine zipper-containing" evidence="5">
        <location>
            <begin position="85"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Apoptosis-antagonizing transcription factor C-terminal" evidence="4">
        <location>
            <begin position="319"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="45"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="400" mass="47808" checksum="993DB112F816CC2C" modified="2017-02-15" version="1">MDLKRNSSKKKKKKNILNKKSSKINNKQSKKGLLKKNKYEKDKLGELYKLEIENFKKEKDQKNEKLTENLELINDDYDNIKEISKKVNDQINLYKVLLRTRILSQKVLSLSNKLPLLSFVSLKDKMLDNDNLSKDIRNSLNEVKCNEEKLKDDIGDLLTILHNFLKKYFLKCDIQINENLFNELNIINDEEDKLFYENRRKLYNEDTTKNEKKLFSIIDTWFLYSKKMCLNFFDIMHKITKISSTKSLKTYEQSISSQINQVMFELPSLIENSYPEALNYEIVGKKLYELLYKDERNFNLNKHIYDDEIYYKKFLLNAIQILKNNQEDSELLKSQREIYKIKKKYDNNNVNRGKILSYEPIPKLVNFMLPEPPDWKNESLYEYVNNPELINVLLSSLFQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUP8</accession>
    <name>A0A1J1GUP8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">GPI transamidase subunit PIG-U, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00243000</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PIGU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527845.1">
        <property type="nucleotide sequence ID" value="XM_028671165.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUP8"/>
    <dbReference type="GeneID" id="39730958"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00243000"/>
    <dbReference type="OMA" id="IYLKIMI"/>
    <dbReference type="OrthoDB" id="549017at2759"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042765">
        <property type="term" value="C:GPI-anchor transamidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016255">
        <property type="term" value="P:attachment of GPI anchor to protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009600">
        <property type="entry name" value="PIG-U"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13121">
        <property type="entry name" value="GPI TRANSAMIDASE COMPONENT PIG-U"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13121:SF0">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL GLYCAN ANCHOR BIOSYNTHESIS CLASS U PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06728">
        <property type="entry name" value="PIG-U"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="246"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="269"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="291"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="369"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="392"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="419"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="462"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="490"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG95032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="552" mass="66573" checksum="46A3A2300A9E2FD0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUT6</accession>
    <name>A0A1J1GUT6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00343600</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Lysosome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529023.1">
        <property type="nucleotide sequence ID" value="XM_028672474.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUT6"/>
    <dbReference type="GeneID" id="39731966"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00343600"/>
    <dbReference type="OMA" id="SCSTHIF"/>
    <dbReference type="OrthoDB" id="372399at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005765">
        <property type="term" value="C:lysosomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052187">
        <property type="entry name" value="MFSD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23512">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23512:SF3">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0458">Lysosome</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="17"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="124"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="320"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="345"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="387"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="830"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="870"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="897"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="928"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="962"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="996"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="682"/>
            <end position="709"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG96218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1043" mass="123439" checksum="CD40253CCA9FC65D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUZ7</accession>
    <name>A0A1J1GUZ7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Translation elongation factor EF-1, subunit alpha, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00350000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529087.1">
        <property type="nucleotide sequence ID" value="XM_028672546.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUZ7"/>
    <dbReference type="GeneID" id="39732030"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00350000"/>
    <dbReference type="OMA" id="IERYEEC"/>
    <dbReference type="OrthoDB" id="342024at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01883">
        <property type="entry name" value="EF1_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03704">
        <property type="entry name" value="eRF3_C_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04089">
        <property type="entry name" value="eRF3_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000020">
        <property type="entry name" value="Translation elongation factor EF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001202">
        <property type="entry name" value="Translation elongation factor EF-1 subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054696">
        <property type="entry name" value="GTP-eEF1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050100">
        <property type="entry name" value="TRAFAC_GTPase_members"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23115">
        <property type="entry name" value="TRANSLATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22594">
        <property type="entry name" value="GTP-eEF1A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="7">
        <location>
            <begin position="116"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="63"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="554" mass="62980" checksum="51103C8CC2F13C3C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV50</accession>
    <name>A0A1J1GV50_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Coatomer subunit delta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00362300</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9 10">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9 10">Cytoplasmic vesicle</location>
            <location evidence="9 10">COPI-coated vesicle membrane</location>
            <topology evidence="9 10">Peripheral membrane protein</topology>
            <orientation evidence="9 10">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9 10">Golgi apparatus membrane</location>
            <topology evidence="9 10">Peripheral membrane protein</topology>
            <orientation evidence="9 10">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529204.1">
        <property type="nucleotide sequence ID" value="XM_028672675.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV50"/>
    <dbReference type="GeneID" id="39732153"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00362300"/>
    <dbReference type="OMA" id="CEDNETT"/>
    <dbReference type="OrthoDB" id="10266042at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051645">
        <property type="term" value="P:Golgi localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09254">
        <property type="entry name" value="AP_delta-COPI_MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14830">
        <property type="entry name" value="Delta_COP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000019">
        <property type="entry name" value="Coatomer subunit delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1170">
        <property type="entry name" value="Mu homology domain, subdomain B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027059">
        <property type="entry name" value="Coatomer_dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10121">
        <property type="entry name" value="COATOMER SUBUNIT DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10121:SF0">
        <property type="entry name" value="COATOMER SUBUNIT DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00928">
        <property type="entry name" value="Adap_comp_sub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 9" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="4 9" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="6 9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="MHD" evidence="11">
        <location>
            <begin position="250"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG96399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="486" mass="56727" checksum="91937B572DD84411" modified="2017-02-15" version="1">MTVLSAVISTKSKILVSRQFRNISKCDLDSLTIPFHNLIERERSDHTYIETDKVRYVYQPLDSIYIFLITNINSNIIEDLEIIKVLSQIIQDICQGNINESTILKKCFTIIFYIDELIKNGVREIVNSNQIKAYIEMESHEEKLQTIIRENKEKEEKERRKFIASKLEKNRQKQNKVTTNSFPSNEYITNLDYNSNIDIYKSEEQYIIDESFNTYKGMQLSTKKENVKILNVVDIKTESKPTINVNSLFSKPINIVITENVICTLSSEGTLCDLDIQGTFNMQINNHKYSKVIMELENDYSEKAKIHPILDKNKYNSNILELKDKSKNFRTNTIYPLLKWKINYLNDSYIPLNISCWPCEDNETTLLNLEIENKRKNNDEIIYDLNVNIMCPSSSNPQIISKDKGVIEHDGILLAWRVDTLKNNQNCQIEISIQSKPESIFPFSVEAKSNILSHKLNVLKVYDEDTKENIEYELKKNITYLFTINK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVA3</accession>
    <name>A0A1J1GVA3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Myosin F, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">MyoF</name>
        <name evidence="10" type="ORF">PGAL8A_00368000</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529260.1">
        <property type="nucleotide sequence ID" value="XM_028672737.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732210"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00368000"/>
    <dbReference type="OMA" id="TPKMFCE"/>
    <dbReference type="OrthoDB" id="6108017at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000146">
        <property type="term" value="F:microfilament motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.4820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140:SF706">
        <property type="entry name" value="DILUTE CLASS UNCONVENTIONAL MYOSIN, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140">
        <property type="entry name" value="MYOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00193">
        <property type="entry name" value="MYOSINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 6" id="KW-0505">Motor protein</keyword>
    <keyword evidence="3 6" id="KW-0518">Myosin</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myosin motor" evidence="9">
        <location>
            <begin position="101"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="414"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="623"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Actin-binding" evidence="6">
        <location>
            <begin position="930"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="274"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="859"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="414"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="441"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="627"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="646"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="202"/>
            <end position="209"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG96455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1584" mass="189104" checksum="83161C759F3AD653" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVB6</accession>
    <name>A0A1J1GVB6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Actin-related protein 2/3 complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00345400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529041.1">
        <property type="nucleotide sequence ID" value="XM_028672494.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVB6"/>
    <dbReference type="GeneID" id="39731984"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00345400"/>
    <dbReference type="OMA" id="TIDMKCV"/>
    <dbReference type="OrthoDB" id="406844at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017383">
        <property type="entry name" value="ARPC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10709">
        <property type="entry name" value="ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10709:SF2">
        <property type="entry name" value="ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0853">WD repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="392" mass="45667" checksum="06E6F5B5AD757445" modified="2017-02-15" version="1">MIVEHIKCECIKYSLPDEDSEPIITASSNVDDLLVAVINNKKNVLLYKIVNKELIYCETFYIGNSNKIIGFEWSKKNELLIITIDMKCIIYIRDEKGIWSYNNVNIPTEELPTCACWHPYAHSFAIGFSSGVIFICSKKNKQKWSIKKLVNHTGSILYLQWNSSGLVLSTNSVDSTSLLICTLDLWEDNIVKKQSIKIFEKIKEFITEKNLKNYDIINKVECKGYIFIYATFSLSNEKVAMIANNFENNCEKQQIIIFDYLKSPIKVHFISWIGQTLHKCLFIDEDKLLVYGYELFPIIIERSNDEWVISKVVLPEFTIKNLTVDFFYDKKDIHDIEKEYNDMHGNKIIGEIVAHSNQILQISMLESYEYKKYTQFITVSSDFNVIVWSFIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVK8</accession>
    <name>A0A1J1GVK8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">G-patch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00415500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529380.1">
        <property type="nucleotide sequence ID" value="XM_028672871.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVK8"/>
    <dbReference type="GeneID" id="39732686"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00415500"/>
    <dbReference type="OMA" id="KVYFFYN"/>
    <dbReference type="OrthoDB" id="392265at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071008">
        <property type="term" value="C:U2-type post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000390">
        <property type="term" value="P:spliceosomal complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045211">
        <property type="entry name" value="TFP11/STIP/Ntr1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23329:SF1">
        <property type="entry name" value="TUFTELIN-INTERACTING PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23329">
        <property type="entry name" value="TUFTELIN-INTERACTING PROTEIN 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1029" mass="125225" checksum="7259A862F0035F80" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW17</accession>
    <name>A0A1J1GW17_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fam-h protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00269350</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000039">
        <property type="protein sequence ID" value="CRG95492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528301.1">
        <property type="nucleotide sequence ID" value="XM_028671672.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW17"/>
    <dbReference type="GeneID" id="39731224"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00269350"/>
    <dbReference type="OMA" id="KISISCF"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="229" mass="26401" checksum="74639143DEA4C449" modified="2017-02-15" version="1">MKSNTIFNIIKFPGFSNHVTKSYLTTNIKNSMICNKKQKISISCFSKFFLFMLLIIILQGFNSYIYKFENSKRKFVVPAHLINIRILSESNNEKLKTELKLKLLDSDEQKGKDKNLLKENLNDNNLDSGTNVYPEGSEDMLDNKNKSEIKRKSFNNGKINMALRSVLIASPLLILMAFSPFKSRTSLYIKKNLFLVYLAYTGGILYSNIISYLKEGDKETNKKEHKKPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWL0</accession>
    <name>A0A1J1GWL0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Sugar transporter, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00428900</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529513.1">
        <property type="nucleotide sequence ID" value="XM_028673018.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWL0"/>
    <dbReference type="GeneID" id="39732821"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00428900"/>
    <dbReference type="OrthoDB" id="6770063at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06174">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044770">
        <property type="entry name" value="MFS_spinster-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23505:SF9">
        <property type="entry name" value="PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23505">
        <property type="entry name" value="SPINSTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="711"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="753"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="780"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="839"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="888"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1010"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1047"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1085"/>
            <end position="1103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1109"/>
            <end position="1130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1151"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1189"/>
            <end position="1207"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="715"/>
            <end position="1212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="918"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="926"/>
            <end position="937"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG96709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1226" mass="142101" checksum="7805444149CB79D8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWQ9</accession>
    <name>A0A1J1GWQ9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Apicoplast ribosomal protein S6, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RPS6</name>
        <name evidence="3" type="ORF">PGAL8A_00445700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529679.1">
        <property type="nucleotide sequence ID" value="XM_028673203.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWQ9"/>
    <dbReference type="GeneID" id="39732990"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00445700"/>
    <dbReference type="OrthoDB" id="375701at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00360">
        <property type="entry name" value="Ribosomal_bS6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000529">
        <property type="entry name" value="Ribosomal_bS6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035980">
        <property type="entry name" value="Ribosomal_bS6_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020814">
        <property type="entry name" value="Ribosomal_S6_plastid/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribsomal_bS6"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00166">
        <property type="entry name" value="S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01250">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54995">
        <property type="entry name" value="Ribosomal protein S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013380403" evidence="2">
        <location>
            <begin position="26"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="223" mass="27043" checksum="67B94FCB9D9F8E84" modified="2017-02-15" version="1">MHIIFKCFLFFLCFFLLVLLDICKSYKIQKLDKYYIQNVNKYNNHFTFKKNGENKKLKIFKKYKLHGSLNDYIYKLLIRKFKKQKVKKDVNIYKTLQSAKSSYNIDFLFSCNFQLSEIKQKLAEYSYELKLIDAEKIKIMYLGKKKLVRPIKKQLEAYYILFSMEIYPSMIKEISEKLKLQIHVLRFIITKNKKESRTIEYKENDSIKGSVLKVEQNFFKKIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWT2</accession>
    <name>A0A1J1GWT2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00268000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000037">
        <property type="protein sequence ID" value="CRG95478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528288.1">
        <property type="nucleotide sequence ID" value="XM_028671658.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWT2"/>
    <dbReference type="GeneID" id="39731210"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00268000"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="139" mass="16893" checksum="D5A4C2B246ED940B" modified="2017-02-15" version="1">MKSFTLYLKIFTFLHLIWIFHCFYKYDSSKSLINRDTLQTEIGLKHERMLAEGDISEKKSSYIEKDIEHYTSGDMEIIPDELIYLMDMYIKCYYANIKLDYEISVFFNEENEIIYKCRDKILNAYRKNIKEDSHVEFFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWU4</accession>
    <name>A0A1J1GWU4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Myosin D, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00451500</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529738.1">
        <property type="nucleotide sequence ID" value="XM_028673268.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733048"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00451500"/>
    <dbReference type="OMA" id="HIYDIGN"/>
    <dbReference type="OrthoDB" id="370884at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000146">
        <property type="term" value="F:microfilament motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140:SF706">
        <property type="entry name" value="DILUTE CLASS UNCONVENTIONAL MYOSIN, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140">
        <property type="entry name" value="MYOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00193">
        <property type="entry name" value="MYOSINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="2 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 6" id="KW-0505">Motor protein</keyword>
    <keyword evidence="3 6" id="KW-0518">Myosin</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myosin motor" evidence="9">
        <location>
            <begin position="105"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Actin-binding" evidence="6">
        <location>
            <begin position="919"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1148"/>
            <end position="1216"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1321"/>
            <end position="1352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="277"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="206"/>
            <end position="213"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG96935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1990" mass="238931" checksum="0B4B2955799F554E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWX6</accession>
    <name>A0A1J1GWX6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Queuine tRNA-ribosyltransferase, putative</fullName>
            <ecNumber evidence="4">2.4.2.29</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00462900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.29" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529852.1">
        <property type="nucleotide sequence ID" value="XM_028673395.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWX6"/>
    <dbReference type="GeneID" id="39733162"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00462900"/>
    <dbReference type="OMA" id="SHRWYIR"/>
    <dbReference type="OrthoDB" id="10249838at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002099">
        <property type="term" value="P:tRNA wobble guanine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.105">
        <property type="entry name" value="Queuine tRNA-ribosyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050076">
        <property type="entry name" value="ArchSynthase1/Queuine_TRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036511">
        <property type="entry name" value="TGT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002616">
        <property type="entry name" value="tRNA_ribo_trans-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00449">
        <property type="entry name" value="tgt_general"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46499">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46499:SF1">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01702">
        <property type="entry name" value="TGT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51713">
        <property type="entry name" value="tRNA-guanine transglycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-guanine(15) transglycosylase-like" evidence="3">
        <location>
            <begin position="149"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-guanine(15) transglycosylase-like" evidence="3">
        <location>
            <begin position="308"/>
            <end position="612"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="613" mass="72513" checksum="174B43B4355F1B00" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWY1</accession>
    <name>A0A1J1GWY1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dynein light chain, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00440300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529625.1">
        <property type="nucleotide sequence ID" value="XM_028673142.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWY1"/>
    <dbReference type="GeneID" id="39732936"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00440300"/>
    <dbReference type="OMA" id="VNQWTSA"/>
    <dbReference type="OrthoDB" id="10059120at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21455">
        <property type="entry name" value="DLC-like_DYNLT1_DYNLT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.40">
        <property type="entry name" value="Tctex-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005334">
        <property type="entry name" value="Tctex-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038586">
        <property type="entry name" value="Tctex-1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21255:SF4">
        <property type="entry name" value="DYNEIN LIGHT CHAIN TCTEX-TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21255">
        <property type="entry name" value="T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03645">
        <property type="entry name" value="Tctex-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="112" mass="12990" checksum="E14CCA556835F33B" modified="2017-02-15" version="1">MNDTDKFEEEFDIEQMEEIGKQTISQFLEKMHYNEEKTNFWVSQILDTTLKELSKLNKPFKYIATCILMEKNGSPLTTSNVCLWDENSDGLCSVQMGNETLDCILCIYAIKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX44</accession>
    <name>A0A1J1GX44_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00459200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529815.1">
        <property type="nucleotide sequence ID" value="XM_028673354.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733125"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00459200"/>
    <dbReference type="OMA" id="FRNTFYT"/>
    <dbReference type="OrthoDB" id="387052at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="472"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="115"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1131"/>
            <end position="1278"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1384"/>
            <end position="1422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="152"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1865" mass="215250" checksum="3A78900C624BB7AB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX91</accession>
    <name>A0A1J1GX91_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00476600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529990.1">
        <property type="nucleotide sequence ID" value="XM_028673549.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX91"/>
    <dbReference type="GeneID" id="39733299"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00476600"/>
    <dbReference type="OMA" id="NQISYMI"/>
    <dbReference type="OrthoDB" id="5411773at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15522">
        <property type="entry name" value="PHD_TAF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024610">
        <property type="entry name" value="ING_N_histone-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01408">
        <property type="entry name" value="ING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="7">
        <location>
            <begin position="613"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="164"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="308"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="22"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="177"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="677" mass="80111" checksum="408B1E8F24ED1FF9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXB6</accession>
    <name>A0A1J1GXB6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00470000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529922.1">
        <property type="nucleotide sequence ID" value="XM_028673473.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXB6"/>
    <dbReference type="GeneID" id="39733233"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00470000"/>
    <dbReference type="OrthoDB" id="371374at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="53"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="179" mass="21516" checksum="B4C913CBB91B6276" modified="2017-02-15" version="1">MCKELDILNLLKKIKTKTNKISNDIEGFDFDLLEEDSNVFCDMYTIRELICWNNTKEKDLDKYKDVYNNYENEINFYFNEEVEKIIYSSLINKDGEFLIKPKDETIYKSSNIIDQKLNHTMLEYKKLRNYQYNVKYFKPVNLDNKRNFSDSSISSNKDNKNIECNLKDITKIIKQYTIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXE4</accession>
    <name>A0A1J1GXE4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">CDGSH iron-sulfur domain-containing protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00482200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530046.1">
        <property type="nucleotide sequence ID" value="XM_028673611.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXE4"/>
    <dbReference type="GeneID" id="39733355"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00482200"/>
    <dbReference type="OMA" id="FKPLMYI"/>
    <dbReference type="OrthoDB" id="15717at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.90">
        <property type="entry name" value="CDGSH iron-sulfur domain, mitoNEET-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052950">
        <property type="entry name" value="CISD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018967">
        <property type="entry name" value="FeS-contain_CDGSH-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042216">
        <property type="entry name" value="MitoNEET_CISD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46491">
        <property type="entry name" value="CDGSH IRON SULFUR DOMAIN PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46491:SF3">
        <property type="entry name" value="CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09360">
        <property type="entry name" value="zf-CDGSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00704">
        <property type="entry name" value="ZnF_CDGSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Iron-binding zinc finger CDGSH type" evidence="7">
        <location>
            <begin position="20"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="118" mass="13777" checksum="71441AD4A731FB4E" modified="2017-02-15" version="1">MSWGQWWPHDPVVKTDLVDPYLVKVEKKKVYWYCTCGTSKIQPWCDGSHKGTGFKPLMYIPQSSGYRLLCGCKQSLHKPHYDFTDLWVRANRNVPKAALFTYVALFSFGIMTTWLFHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXF9</accession>
    <name>A0A1J1GXF9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00482800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530052.1">
        <property type="nucleotide sequence ID" value="XM_028673617.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXF9"/>
    <dbReference type="GeneID" id="39733361"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00482800"/>
    <dbReference type="OrthoDB" id="370908at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="97" mass="11795" checksum="4E0A2A57B23101C1" modified="2017-02-15" version="1">MVIKNNQDKKRNFKILLERRIILSQESEKHIDKSIYTFYGICLISLSISAFIFSSMFFFFKMHPYAIYYFIVNVGSIPIYILYQYFKWISLELFKYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXW2</accession>
    <name>A0A1J1GXW2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00497700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000101">
        <property type="protein sequence ID" value="CRG97402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530204.1">
        <property type="nucleotide sequence ID" value="XM_028673786.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXW2"/>
    <dbReference type="GeneID" id="39733510"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00497700"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="138" mass="16943" checksum="FF2D73BF95C1750B" modified="2017-02-15" version="1">MKTFTLYLKIFTFFLIWIFHCFYNYDFSSCFFYKDTLQMKNRLKDERMLTEGGILEKKQTCIKKSLEHYPSSEGEFNIREFVYLMDMFIKCYSNIILSRSQEHVLFKEENEMRYKCRDKILNAYRNNIIEDELTALFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY27</accession>
    <name>A0A1J1GY27_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">methionine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Methionyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00494400</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.10" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530167.1">
        <property type="nucleotide sequence ID" value="XM_028673745.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY27"/>
    <dbReference type="GeneID" id="39733477"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00494400"/>
    <dbReference type="OrthoDB" id="5844513at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004825">
        <property type="term" value="F:methionine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006431">
        <property type="term" value="P:methionyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00814">
        <property type="entry name" value="MetRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.220.10:FF:000002">
        <property type="entry name" value="Methionine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.730.10:FF:000043">
        <property type="entry name" value="Methionine-tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041872">
        <property type="entry name" value="Anticodon_Met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014758">
        <property type="entry name" value="Met-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023457">
        <property type="entry name" value="Met-tRNA_synth_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033911">
        <property type="entry name" value="MetRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00398">
        <property type="entry name" value="metG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43326:SF2">
        <property type="entry name" value="METHIONINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43326">
        <property type="entry name" value="METHIONYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19303">
        <property type="entry name" value="Anticodon_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01041">
        <property type="entry name" value="TRNASYNTHMET"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methionyl/Leucyl tRNA synthetase" evidence="9">
        <location>
            <begin position="215"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Leucyl tRNA synthetase" evidence="9">
        <location>
            <begin position="363"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl-tRNA synthetase anticodon-binding" evidence="10">
        <location>
            <begin position="597"/>
            <end position="711"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF19303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG97365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="875" mass="102850" checksum="D2FE0EA6C4BC42F0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY47</accession>
    <name>A0A1J1GY47_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00021950</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000106">
        <property type="protein sequence ID" value="CRG97408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530210.1">
        <property type="nucleotide sequence ID" value="XM_028673793.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY47"/>
    <dbReference type="GeneID" id="39728742"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00021950"/>
    <dbReference type="OMA" id="VYEYQVY"/>
    <dbReference type="OrthoDB" id="196717at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014472">
        <property type="entry name" value="CHOPT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10414:SF37">
        <property type="entry name" value="BB IN A BOXCAR, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10414">
        <property type="entry name" value="ETHANOLAMINEPHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="82"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="136" mass="16869" checksum="05B46E83F3C72748" modified="2017-02-15" version="1">MGIFLKLNKNVYSNCKSYVYKSSGGSILDNIFNVYWSICVNFVPKSITANLLTLLGFLCSTIAFFLMYLFDPLEEKYNYIYIYIGLFLFLYQVRFFFFFFFFFFFFFKFLNFFFFFFFFFFFFFFFFLYVVGFYLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYB2</accession>
    <name>A0A1J1GYB2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00320500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528800.1">
        <property type="nucleotide sequence ID" value="XM_028672227.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYB2"/>
    <dbReference type="GeneID" id="39731738"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00320500"/>
    <dbReference type="OMA" id="SAFENMI"/>
    <dbReference type="OrthoDB" id="378232at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="246" mass="29517" checksum="07391CB08C090ADD" modified="2017-02-15" version="1">MKFIFSLHLIILTISFSCLRNFSFLYFIYKIKNDNSLHFLRANLKNNKFEYIRKLMEEDRLKIHLEDKLIDDFINYYNVADSSDFEEIIDPTIFDNLDEIEKIESSNKNTQVYKDERDKKRNKKKYSTNKSCESTEKACNAHIRDNLRTQRRAPKRYLDNEFYYDTSLNIDYKIKCNKNRRNNKRPSNYKRGVDKKTHKDKSHVIKKLSELNMNSKEEKIDNDVFTKFNSPTIDVAHDKAGPSHRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYB3</accession>
    <name>A0A1J1GYB3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00349000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529077.1">
        <property type="nucleotide sequence ID" value="XM_028672535.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYB3"/>
    <dbReference type="GeneID" id="39732020"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00349000"/>
    <dbReference type="OMA" id="YGFPFFW"/>
    <dbReference type="OrthoDB" id="370254at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="830" mass="99337" checksum="B2C1335818AEA1E1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYE9</accession>
    <name>A0A1J1GYE9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DnaJ protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00353000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529117.1">
        <property type="nucleotide sequence ID" value="XM_028672579.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYE9"/>
    <dbReference type="GeneID" id="39732060"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00353000"/>
    <dbReference type="OMA" id="EICENDQ"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="899"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="223"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="962" mass="114305" checksum="E895E7A20A3AEE2B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYN5</accession>
    <name>A0A1J1GYN5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Condensin-2 complex subunit D3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00363200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529213.1">
        <property type="nucleotide sequence ID" value="XM_028672685.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732162"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00363200"/>
    <dbReference type="OMA" id="KHENSFI"/>
    <dbReference type="OrthoDB" id="10263978at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000779">
        <property type="term" value="C:condensed chromosome, centromeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010032">
        <property type="term" value="P:meiotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026971">
        <property type="entry name" value="CND1/NCAPD3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14222">
        <property type="entry name" value="CONDENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14222:SF2">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1188"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1333"/>
            <end position="1356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1092"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1673"/>
            <end position="1724"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="231"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="546"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="906"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1092"/>
            <end position="1108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1705"/>
            <end position="1724"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1724" mass="206462" checksum="62F3369B40606784" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYU1</accession>
    <name>A0A1J1GYU1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Calcium/calmodulin-dependent protein kinase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00520000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530425.1">
        <property type="nucleotide sequence ID" value="XM_028674031.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYU1"/>
    <dbReference type="GeneID" id="39733733"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00520000"/>
    <dbReference type="OMA" id="TVCLCEW"/>
    <dbReference type="OrthoDB" id="1738954at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="140"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="445" mass="52383" checksum="474EC6A4655BF040" modified="2017-02-15" version="1">MSLKKTPFSFLSGISSNKNNENSKWEKTILSRKNSYEHIKESKVSEFGDFKILNVLLRGLSSIVCLCEWTIDLSRTLYLNHYVNYINNNILNENIQIKIRDTTNTDNISIMSNNKDTNTTVEIKDREKLEYCDIYDIEKSKNKKEIKNGEYNLEKINFKYNNNKIIHLVLKLKHKGLNYKISEIEQLREEIAIHKELNHFNILQMILCGEDENDIWVFFEYSSIGDLYSYVGFKTLEENEVKIIVSQILFALYYLHMNGIIHCDIKLQNILLFPLEPSLFERNDLSNTLKMNNSKKIKLNINKLLDSINENNQSNKNNNTFKSIIKLCDFGLSVKCKFDEFYPYRGIKGSSGFIAPELFQECDFNNKIDMWALGIIVFILLGGYRPFYPYSRFEEKVTFHERYWINISPEAKNFIQSLLQINPSKRLNVIEAMNHPWIKSYFIIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYY4</accession>
    <name>A0A1J1GYY4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00344500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529032.1">
        <property type="nucleotide sequence ID" value="XM_028672484.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731975"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00344500"/>
    <dbReference type="OMA" id="EDEHQYK"/>
    <dbReference type="OrthoDB" id="382551at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="409"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="164"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="427"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="459"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1348" mass="159210" checksum="093245A4730D9C25" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYZ8</accession>
    <name>A0A1J1GYZ8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Cop-coated vesicle membrane protein p24, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00510800</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the EMP24/GP25L family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530336.1">
        <property type="nucleotide sequence ID" value="XM_028673933.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYZ8"/>
    <dbReference type="GeneID" id="39733641"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00510800"/>
    <dbReference type="OMA" id="QEKMMET"/>
    <dbReference type="OrthoDB" id="62956at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015720">
        <property type="entry name" value="Emp24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009038">
        <property type="entry name" value="GOLD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22811">
        <property type="entry name" value="TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01105">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01190">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50866">
        <property type="entry name" value="GOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012837008" evidence="9">
        <location>
            <begin position="24"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="GOLD" evidence="10">
        <location>
            <begin position="33"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG97535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="205" mass="24490" checksum="2F7A9322E9B1D9AB" modified="2017-02-15" version="1">MNFFKHKIFIFFFLVLQLQKIYCTHFTITAHEKDCFHFKAETNNFIVGSYEIIDTNSSCIITILNRQDKNNDYLFKSRNSQDKFEIQAKTTGMHSFCYENKGNSDITIMFTLRVKEVHGTNESDLSTVDDVQKINDEAYELYEQFLEVYDEQERMMEKADLYKQFNEKINSKLILWSEIQIILLIILTLIHIYYIKSFFEIKTIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ03</accession>
    <name>A0A1J1GZ03_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VHS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00503800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530266.1">
        <property type="nucleotide sequence ID" value="XM_028673855.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ03"/>
    <dbReference type="GeneID" id="39733571"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00503800"/>
    <dbReference type="OrthoDB" id="366185at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002014">
        <property type="entry name" value="VHS_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48464">
        <property type="entry name" value="ENTH/VHS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50179">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VHS" evidence="2">
        <location>
            <begin position="322"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="558"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1187"/>
            <end position="1222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="558"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="585"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1199"/>
            <end position="1212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1255" mass="146710" checksum="EF906C4F3DC70FFB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZI7</accession>
    <name>A0A1J1GZI7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Stearoyl-CoA desaturase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PGAL8A_00032400</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11">The histidine box domains are involved in binding the catalytic metal ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the fatty acid desaturase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530686.1">
        <property type="nucleotide sequence ID" value="XM_028674322.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZI7"/>
    <dbReference type="GeneID" id="39728847"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00032400"/>
    <dbReference type="OMA" id="VYECKRG"/>
    <dbReference type="OrthoDB" id="1533126at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004768">
        <property type="term" value="F:stearoyl-CoA 9-desaturase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006636">
        <property type="term" value="P:unsaturated fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03505">
        <property type="entry name" value="Delta9-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015876">
        <property type="entry name" value="Acyl-CoA_DS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351">
        <property type="entry name" value="ACYL-COA DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351:SF31">
        <property type="entry name" value="DESATURASE 1, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00075">
        <property type="entry name" value="FACDDSATRASE"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10 11" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="3 11" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="270"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="303"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="333"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="359"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="392"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="480"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="661"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="705"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="749"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="789"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="816"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="146"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG97887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="948" mass="113715" checksum="84E3796B26BA7FC4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZS0</accession>
    <name>A0A1J1GZS0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00055300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530915.1">
        <property type="nucleotide sequence ID" value="XM_028674576.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729078"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00055300"/>
    <dbReference type="OMA" id="IDICEYS"/>
    <dbReference type="OrthoDB" id="386592at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1120"/>
            <end position="1148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1644"/>
            <end position="1746"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2250"/>
            <end position="2287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2993"/>
            <end position="3028"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1280"/>
            <end position="1314"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1418"/>
            <end position="1461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1652"/>
            <end position="1676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1677"/>
            <end position="1686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1707"/>
            <end position="1724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1725"/>
            <end position="1746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2250"/>
            <end position="2283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2993"/>
            <end position="3005"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3633" mass="432150" checksum="0D1E1E7C2EF55783" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZU0</accession>
    <name>A0A1J1GZU0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00040500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000127">
        <property type="protein sequence ID" value="CRG97970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530769.1">
        <property type="nucleotide sequence ID" value="XM_028674413.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZU0"/>
    <dbReference type="GeneID" id="39728929"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00040500"/>
    <dbReference type="OrthoDB" id="348930at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="775"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="369"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="576"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="387"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="437"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="452"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="478"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="576"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="599"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="623"/>
            <end position="637"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="874" mass="97285" checksum="E3331E2F66742D98" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZU2</accession>
    <name>A0A1J1GZU2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PIR-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00053100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000134">
        <property type="protein sequence ID" value="CRG98096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530893.1">
        <property type="nucleotide sequence ID" value="XM_028674552.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZU2"/>
    <dbReference type="GeneID" id="39729056"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00053100"/>
    <dbReference type="OrthoDB" id="394175at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="72" mass="8587" checksum="78609BD8C34EA5E0" modified="2017-02-15" version="1" fragment="single">YTRIGSLLGKGNLQKEKGRKRLRETSLDNIEDPSESSMEKEEMKPKRSRLNSFLRAFGYKYRNIFPYIDENR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZU9</accession>
    <name>A0A1J1GZU9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Phosphatidylserine decarboxylase proenzyme</fullName>
            <ecNumber evidence="12">4.1.1.65</ecNumber>
        </recommendedName>
        <component>
            <recommendedName>
                <fullName evidence="12">Phosphatidylserine decarboxylase beta chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="12">Phosphatidylserine decarboxylase alpha chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="14" type="primary">PSD</name>
        <name evidence="14" type="ORF">PGAL8A_00440700</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-L-serine + H(+) = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CO2</text>
            <dbReference type="Rhea" id="RHEA:20828"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="EC" id="4.1.1.65"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
        <text evidence="12">Binds 1 pyruvoyl group covalently per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Endoplasmic reticulum membrane</location>
            <topology evidence="12">Single-pass membrane protein</topology>
        </subcellularLocation>
        <text evidence="12">Equally found in the membrane-bound as well as in the soluble fraction.</text>
    </comment>
    <comment type="PTM">
        <text evidence="12">Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.65" evidence="12"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529629.1">
        <property type="nucleotide sequence ID" value="XM_028673147.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZU9"/>
    <dbReference type="GeneID" id="39732940"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00440700"/>
    <dbReference type="OMA" id="KDYHHYH"/>
    <dbReference type="OrthoDB" id="4330at2759"/>
    <dbReference type="UniPathway" id="UPA00558">
        <property type="reaction ID" value="UER00616"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004609">
        <property type="term" value="F:phosphatidylserine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016540">
        <property type="term" value="P:protein autoprocessing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03208">
        <property type="entry name" value="PS_decarb_PSD_B_type1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003817">
        <property type="entry name" value="PS_Dcarbxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033177">
        <property type="entry name" value="PSD-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033661">
        <property type="entry name" value="PSD_type1_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00163">
        <property type="entry name" value="PS_decarb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10067:SF6">
        <property type="entry name" value="PHOSPHATIDYLSERINE DECARBOXYLASE PROENZYME, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02666">
        <property type="entry name" value="PS_Dcarbxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="2 12" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6 12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 12 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 12" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="11 12" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="12" id="KW-0865">Zymogen</keyword>
    <feature type="chain" id="PRO_5023217332" description="Phosphatidylserine decarboxylase beta chain" evidence="12">
        <location>
            <begin position="1"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023217334" description="Phosphatidylserine decarboxylase alpha chain" evidence="12">
        <location>
            <begin position="308"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="12">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="12">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system; for autoendoproteolytic cleavage activity" evidence="12">
        <location>
            <position position="308"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity" evidence="12">
        <location>
            <position position="308"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage (non-hydrolytic); by autocatalysis" evidence="12">
        <location>
            <begin position="307"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="modified residue" description="Pyruvic acid (Ser); by autocatalysis" evidence="12">
        <location>
            <position position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG96826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="354" mass="41877" checksum="70D99198D5C229EB" modified="2017-02-15" version="1">MKKKRNNVNTYGLYKRKYIITGVTLLSFILMFQYKYHEVLSVYDDQINVKQSSKLFWTRLIFGRTRSRITGKIFNIEIPSSYRLLVYNSLIKYMNINKDEIKYPIESYRSISDFFSRYIREETRPIEDLSDYSIVSPCDSEIIDFGELKTDYLENIKGLKFNVKNFLGSNLKKKYNDDSTKFYYVIFYLSPRKYHHFHAPFNFKYKIRRHISGELFPVFQGMFKFINNLFDINERVILTGEWKGGNVYYAAVSAYNVGNIKIINDDDLLTNNLRTQLSYMGGDIDTKIYDNYKDLEVGDEIGEFKMGSSIILIFENKSDFLWNIKHNQNVCVGQRIGGINEIIESKDRFIKIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZY6</accession>
    <name>A0A1J1GZY6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NifU-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">IscU2</name>
        <name evidence="3" type="ORF">PGAL8A_00443900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NifU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529661.1">
        <property type="nucleotide sequence ID" value="XM_028673182.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZY6"/>
    <dbReference type="GeneID" id="39732972"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00443900"/>
    <dbReference type="OrthoDB" id="565552at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.130:FF:000015">
        <property type="entry name" value="NifU-like protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="entry name" value="Fe-S cluster assembly (FSCA)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001075">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11178">
        <property type="entry name" value="IRON-SULFUR CLUSTER SCAFFOLD PROTEIN NFU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11178:SF1">
        <property type="entry name" value="NFU1 IRON-SULFUR CLUSTER SCAFFOLD HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01106">
        <property type="entry name" value="NifU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="Fe-S cluster assembly (FSCA) domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NIF system FeS cluster assembly NifU C-terminal" evidence="2">
        <location>
            <begin position="111"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="188" mass="21940" checksum="B0706F2217EE8DB0" modified="2017-02-15" version="1">MIHFKNISNKLLCFKWKIKFNTYKKASVHFSDYVKIQNKYPINKITPAFFSTSKNSDYINYINDINSFLDIFQKNLESTSNNENIVSVLQKIKNEKKYEENEDILEIISSIKLLIEKRVRPIILNDGGDIKFICFDIDSGIVYVQLEGACVTCSQSEMTLQYMIKNMLTYYISEIKEIKNVTKNGDII</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H009</accession>
    <name>A0A1J1H009_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00418500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529408.1">
        <property type="nucleotide sequence ID" value="XM_028672902.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732716"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00418500"/>
    <dbReference type="OMA" id="FNEPSVM"/>
    <dbReference type="OrthoDB" id="387657at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="436"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1542"/>
            <end position="1568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1849"/>
            <end position="1895"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="441"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="462"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="524"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="548"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="581"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="596"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1543"/>
            <end position="1567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1857"/>
            <end position="1871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1872"/>
            <end position="1884"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1991" mass="238210" checksum="BEB7668E504EC282" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H061</accession>
    <name>A0A1J1H061_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin carboxyl-terminal hydrolase 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00038200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530744.1">
        <property type="nucleotide sequence ID" value="XM_028674385.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H061"/>
    <dbReference type="GeneID" id="39728906"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00038200"/>
    <dbReference type="OMA" id="KKNHRIW"/>
    <dbReference type="OrthoDB" id="265776at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000046">
        <property type="entry name" value="ubiquitin carboxyl-terminal hydrolase 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050185">
        <property type="entry name" value="Ub_carboxyl-term_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21646:SF46">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="USP" evidence="2">
        <location>
            <begin position="283"/>
            <end position="1148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="746"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="871"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="746"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="879"/>
            <end position="893"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1179" mass="139127" checksum="4DBE89AFD51DFC8F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0C4</accession>
    <name>A0A1J1H0C4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00058300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NELF-D family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530945.1">
        <property type="nucleotide sequence ID" value="XM_028674609.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729108"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00058300"/>
    <dbReference type="OrthoDB" id="364993at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032021">
        <property type="term" value="C:NELF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034244">
        <property type="term" value="P:negative regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006942">
        <property type="entry name" value="TH1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12144:SF0">
        <property type="entry name" value="NEGATIVE ELONGATION FACTOR C_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12144">
        <property type="entry name" value="NEGATIVE ELONGATION FACTOR D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="989"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="996"/>
            <end position="1088"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG98148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1690" mass="204515" checksum="AEBD75BC143B3E81" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0D1</accession>
    <name>A0A1J1H0D1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Flap endonuclease 1</fullName>
            <shortName evidence="16">FEN-1</shortName>
            <ecNumber evidence="16">3.1.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Flap structure-specific endonuclease 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="primary">FEN1</name>
        <name evidence="22" type="ORF">PGAL8A_00059100</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 16">Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="16">Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Interacts with PCNA1 and PCNA2. Three molecules of FEN1 bind to one PCNA trimer with each molecule binding to one PCNA monomer. PCNA stimulates the nuclease activity without altering cleavage specificity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="16">Nucleus</location>
            <location evidence="16">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="16">Nucleus</location>
            <location evidence="16">Nucleoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="16">Mitochondrion</location>
        </subcellularLocation>
        <text evidence="16">Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.</text>
    </comment>
    <comment type="similarity">
        <text evidence="14 16">Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="16"/>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530953.1">
        <property type="nucleotide sequence ID" value="XM_028674618.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0D1"/>
    <dbReference type="GeneID" id="39729116"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00059100"/>
    <dbReference type="OMA" id="MGIPWVQ"/>
    <dbReference type="OrthoDB" id="1937206at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008409">
        <property type="term" value="F:5'-3' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043137">
        <property type="term" value="P:DNA replication, removal of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09907">
        <property type="entry name" value="H3TH_FEN1-Euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09867">
        <property type="entry name" value="PIN_FEN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000009">
        <property type="entry name" value="Flap endonuclease 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1010:FF:000016">
        <property type="entry name" value="Flap endonuclease 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00614">
        <property type="entry name" value="Fen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002421">
        <property type="entry name" value="5-3_exonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023426">
        <property type="entry name" value="Flap_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006086">
        <property type="entry name" value="XPG-I_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019974">
        <property type="entry name" value="XPG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006085">
        <property type="entry name" value="XPG_DNA_repair_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081:SF9">
        <property type="entry name" value="FLAP ENDONUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081">
        <property type="entry name" value="FLAP ENDONUCLEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00867">
        <property type="entry name" value="XPG_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00752">
        <property type="entry name" value="XPG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00853">
        <property type="entry name" value="XPGRADSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00475">
        <property type="entry name" value="53EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00484">
        <property type="entry name" value="XPGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00485">
        <property type="entry name" value="XPGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00841">
        <property type="entry name" value="XPG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00842">
        <property type="entry name" value="XPG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="17" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 16" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11 16" id="KW-0234">DNA repair</keyword>
    <keyword evidence="2 16" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5 16 22" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8 16" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="7 16" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 16" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 16" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 16" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12 16" id="KW-0539">Nucleus</keyword>
    <keyword evidence="1 16" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XPG N-terminal" evidence="21">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="5'-3' exonuclease" evidence="19">
        <location>
            <begin position="28"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="XPG-I" evidence="20">
        <location>
            <begin position="148"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="387"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="17">
        <location>
            <begin position="99"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="398"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="442"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00034726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00063178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="SMART" id="SM00475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="SMART" id="SM00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="SMART" id="SM00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="CRG98156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="560" mass="63821" checksum="C97AADB8EB74C8AC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H132</accession>
    <name>A0A1J1H132_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF4200 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00482900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530053.1">
        <property type="nucleotide sequence ID" value="XM_028673618.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H132"/>
    <dbReference type="GeneID" id="39733362"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00482900"/>
    <dbReference type="OMA" id="AWKLSMT"/>
    <dbReference type="OrthoDB" id="378702at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051147">
        <property type="entry name" value="CFAP_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025252">
        <property type="entry name" value="DUF4200"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21683:SF3">
        <property type="entry name" value="CILIA AND FLAGELLA ASSOCIATED PROTEIN 100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21683">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 42 LIKE-2-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13863">
        <property type="entry name" value="DUF4200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4200" evidence="4">
        <location>
            <begin position="131"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="73"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="159"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="294"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="82"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="481" mass="58741" checksum="38A69BDB2820E979" modified="2017-02-15" version="1" fragment="single">IIEKEKLITRENYKDIKNFEKKTEEFSYNYTSLIIPSDISSENNSDKNDDIKEVINFHKDKEIEIIKQKLEEKKKEKKKKGSEKLKEQKWNNKTKLYENKNNNRDKKENKKKSALANNKLLKKNKSNIRDFINLEKEIFIAKTLMYKKKEKIDDIYKYTRKKEKIINNLNKNMNKESEKFQQSLMENFQKTEELIKRFEEVSSKKKKKKNQVQSLNIEISKLDVEYEKKEEKIKELDKYKFFLNKLANSDKLDENLFSDNQNENKEDNFSKKMEKYIKNSQLLIDNFNLLEEKHLQLIDDAQNAEYELEEHEKKYEEKKKAFEIKNNEIDKKIKDVKDFIKDHNDKIFQYENLIKNNQDQISFNNINNKIDYICTQFCYDINTDEIMKKLQILENKIYSYIATLTKYIEENSQLVYEYQREREQERRKQMRFEINLDRKSNNQNKLLKNKKVNNKNFTTNLKEKKEKRENIYMKFEKDLFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1K5</accession>
    <name>A0A1J1H1K5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Methyltransferase-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00499100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic/archaeal PrmC-related family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530220.1">
        <property type="nucleotide sequence ID" value="XM_028673804.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1K5"/>
    <dbReference type="GeneID" id="39733524"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00499100"/>
    <dbReference type="OMA" id="EWDDWME"/>
    <dbReference type="OrthoDB" id="406152at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035657">
        <property type="term" value="C:eRF1 methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052190">
        <property type="entry name" value="Euk-Arch_PrmC-MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004557">
        <property type="entry name" value="PrmC-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00537">
        <property type="entry name" value="hemK_rel_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45875">
        <property type="entry name" value="METHYLTRANSFERASE N6AMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45875:SF1">
        <property type="entry name" value="METHYLTRANSFERASE N6AMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase small" evidence="5">
        <location>
            <begin position="45"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="225" mass="26055" checksum="C7969E049DA009D1" modified="2017-02-15" version="1">MSSSSKIKKINFDFIYNNEEIKNNVYLPSSDTFTFIEALENEVKHIPSDVNIALEMGAGTGYLILSLYEMLLKRNKKLELLYCIDINEAACNCIKNLSNINKVSNVEILNNNLFNNMRKCNQFDLVLFNPPYVPTEEDEMNKTDIVASYSGGKLGREIILKFLLNVYDYVSNKGVIYLLLEKNNIPHEIMNNVDIKKRFNYIELKKKKTLNETIFIYKLSKKLIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2J4</accession>
    <name>A0A1J1H2J4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Protein transport protein SEC20, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00513100</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SEC20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530359.1">
        <property type="nucleotide sequence ID" value="XM_028673958.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2J4"/>
    <dbReference type="GeneID" id="39733664"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00513100"/>
    <dbReference type="OMA" id="NDTRYVW"/>
    <dbReference type="OrthoDB" id="365988at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005606">
        <property type="entry name" value="Sec20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056173">
        <property type="entry name" value="Sec20_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12825">
        <property type="entry name" value="BNIP1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12825:SF0">
        <property type="entry name" value="VESICLE TRANSPORT PROTEIN SEC20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03908">
        <property type="entry name" value="Sec20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="210"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="233"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="Sec20 C-terminal" evidence="11">
        <location>
            <begin position="147"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00037934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG97558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="289" mass="34623" checksum="1BAD25AF49DF8AFA" modified="2017-02-15" version="1">MNENIVSNFVKKNKNVDNFNKINTLINQMKLVDDNLKNLFLSEEGLNDHDSFLLFRSKVSRRIIDYSNTISQFNKIICLENIEKNVKEEYEYHLKNIENYKKKLSLWWNTWEKDYHRLCMKLFLKKKISNNYIENNEEKNKDMYNINLKDTRKMMIDEVNRMKNVKSELLDSSQKLKKQDEIFNSFEMKLKSSAQLIFSLKKKAENDTRYVWYSFFFFLSVCIYIILRRLGFIRAIIAIIKFIISILFYIGGTSFKLYTFIKKITSKNQIESEDLLINIGNDSITTNEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3F7</accession>
    <name>A0A1J1H3F7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00046200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530828.1">
        <property type="nucleotide sequence ID" value="XM_028674480.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728987"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00046200"/>
    <dbReference type="OMA" id="CVTEDLF"/>
    <dbReference type="OrthoDB" id="371921at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="231"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="272"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="554"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="884"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="690"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="556"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="884"/>
            <end position="895"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG98031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1531" mass="186181" checksum="EE35ADC011FFE450" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3R1</accession>
    <name>A0A1J1H3R1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00041500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG97986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530783.1">
        <property type="nucleotide sequence ID" value="XM_028674430.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3R1"/>
    <dbReference type="GeneID" id="39728940"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00041500"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="138" mass="16813" checksum="4BDC6BEE108D7547" modified="2017-02-15" version="1">MKTFTLYLKIFTFLLLIWIFPSFYKYDSSKSLINRDTLQTRIGLKHERMLAEDDISEEKSYYIKKRVEHYPSGEEEMILHELFHLMDIYFTCYNANIKSDFEIEVFLKKENEMRNKCRDKILNTYRNNISWSNVLPEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H418</accession>
    <name>A0A1J1H418_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00053300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000138">
        <property type="protein sequence ID" value="CRG98098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530895.1">
        <property type="nucleotide sequence ID" value="XM_028674554.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H418"/>
    <dbReference type="GeneID" id="39729058"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00053300"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="186" mass="22238" checksum="D25459AAC7E7A2D9" modified="2017-02-15" version="1" fragment="single">YDSYITLIDKNILQTKNELKYERILTEGNTEEKKQTNTEGCLKDRPLDNEKKKGKNPVQYKDPYDQWNKVIIPEMWKRFDQETSGMDSKWKDKKWNVEINKITAANAKDLYLIPRRCDISDEEKSKKIDSIMKEIDSEFEKFLSKCKEEMGDNKTESEYKKDQGKNEKKNNKLNILKFLFCRFDSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKQ8</accession>
    <name>A0A1J1GKQ8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosomal large subunit pseudouridylate synthase, putative</fullName>
            <ecNumber evidence="4">5.4.99.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00068800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pseudouridine synthase RluA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.12" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG92984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525806.1">
        <property type="nucleotide sequence ID" value="XM_028672199.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKQ8"/>
    <dbReference type="GeneID" id="39729213"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00068800"/>
    <dbReference type="OrthoDB" id="428658at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160147">
        <property type="term" value="F:tRNA pseudouridine(38-40) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050188">
        <property type="entry name" value="RluA_PseudoU_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600">
        <property type="entry name" value="MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600:SF87">
        <property type="entry name" value="RNA PSEUDOURIDYLATE SYNTHASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pseudouridine synthase RsuA/RluA-like" evidence="3">
        <location>
            <begin position="72"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="399"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG92984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="495" mass="59061" checksum="00DA5FC95CD9F799" modified="2017-02-15" version="1">MYFGKIFYDVSKYCKQNNILFLIRKYGFSSKNNFKYFLKENTNMIEDGKVNIPSYKSYKGHKLKVIYENDFFFVVNKPYDIKLEKGKYDDIYPSVETLIRQEKKLDVFRICGQLDYATSGLLIVAKDKLSSNILNYNIECKNISKIYLAILYGHLPLDIMHINAPISKIKNEFKMKLCYNYNDYYDNGKYCYSLIYPFKHCYLNNQKVTLCEMRTITGRRHQLRLHSIYIGSGIVGDETYFEDMIINKYKINCSNSNNDKMKDENNNYSIKKLNNDINDIQNIPIKKIELERMMLHCWIILKNKNKQINKLNKSENINFLEDKIFDTDYIICDDELSHYVNEKQRTYEECVLKNDDLININFINYNVKNINKNIKNIDKKLNKKKYDSLLYNSLILENLESAEQNNSNYTLQYNENKENKEIHIKNEKINEEIKKNEKDIDFINNKIETINVTDTYINNKLIDNNLIYKVKNDKYKNPNDLFDDIHDSVNKFNWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKZ3</accession>
    <name>A0A1J1GKZ3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="12">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">CNA</name>
        <name evidence="15" type="ORF">PGAL8A_00079000</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PPP phosphatase family. PP-2B subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="12"/>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525910.1">
        <property type="nucleotide sequence ID" value="XM_028670355.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKZ3"/>
    <dbReference type="GeneID" id="39729315"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00079000"/>
    <dbReference type="OMA" id="YPAACNF"/>
    <dbReference type="OrthoDB" id="5593063at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033192">
        <property type="term" value="F:calmodulin-dependent protein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097720">
        <property type="term" value="P:calcineurin-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07416">
        <property type="entry name" value="MPP_PP2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000031">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041751">
        <property type="entry name" value="MPP_PP2B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043360">
        <property type="entry name" value="PP2B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45673">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0112">Calmodulin-binding</keyword>
    <keyword evidence="5 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="14">
        <location>
            <begin position="144"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="416"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG93088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="527" mass="60929" checksum="D3D8CF4D6F86E182" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL97</accession>
    <name>A0A1J1GL97_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00067700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG92973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525795.1">
        <property type="nucleotide sequence ID" value="XM_028670976.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL97"/>
    <dbReference type="GeneID" id="39729202"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00067700"/>
    <dbReference type="OrthoDB" id="377551at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.31.10">
        <property type="entry name" value="Transcriptional Coactivator Pc4, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009044">
        <property type="entry name" value="ssDNA-bd_transcriptional_reg"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54447">
        <property type="entry name" value="ssDNA-binding transcriptional regulator domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG92973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="299" mass="35144" checksum="D8CBC6DA53BC6C9E" modified="2017-02-15" version="1">MKKNYIIRHFNKIAHVKYYNSTSKNVLNNGKNEYTGNLIKDNIDSKFINLVNKNKYNTYKNRVYNTSMYNNSHPSYMNNNENTNNNLLSHYNYKYDSSNYYQQKYNSNVSNESSDNTSYQYFNIFGSTAMCLIKPIFPDYIINKNKLTIYGKGGFQFMFMRKQNNSNKYDKNNKMNIFLKINSLSSVLSLDSIEKLTNAIVIKGNNNNYLTIDKHKEKKDHIVIKYKYQPSNAIDNNFNEINNNLNIDVNKNININELNEEKKNNFEELHVSSPFTEFLIFQKAANLLLPQLIGWSKPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLH5</accession>
    <name>A0A1J1GLH5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00076700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525883.1">
        <property type="nucleotide sequence ID" value="XM_028670055.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729292"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00076700"/>
    <dbReference type="OMA" id="VEMYSTA"/>
    <dbReference type="OrthoDB" id="371925at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1426"/>
            <end position="1462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1426"/>
            <end position="1449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1450"/>
            <end position="1462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1462" mass="172223" checksum="26B8038D38825303" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLR4</accession>
    <name>A0A1J1GLR4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">rRNA biogenesis protein RRP36</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00105600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Associates with 90S and pre-40S pre-ribosomal particles.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
            <location evidence="1 6">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the RRP36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526172.1">
        <property type="nucleotide sequence ID" value="XM_028673265.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLR4"/>
    <dbReference type="GeneID" id="39729581"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00105600"/>
    <dbReference type="OMA" id="HEAMKDI"/>
    <dbReference type="OrthoDB" id="448446at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009292">
        <property type="entry name" value="RRP36"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21738">
        <property type="entry name" value="RIBOSOMAL RNA PROCESSING PROTEIN 36 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21738:SF0">
        <property type="entry name" value="RIBOSOMAL RNA PROCESSING PROTEIN 36 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06102">
        <property type="entry name" value="RRP36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 6" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="69"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="187" mass="22773" checksum="EC41DE6C2059B499" modified="2017-02-15" version="1">MEQNQSKNQKKIKIKKSQKPLVVSNRKPFNVSEKKKNSKPQVRDPRFSEFSGAFNPNFFKKAYKFLYDSREEEKKLIEKKLKSKNLKEEEKIELKKKYNNYKSVDVLLKKKEEERKLKLQLVKEEKEKILTKNKKPFYYSDRKIKKMVEEKFSNNKSIKKVTKKEKRILQKEKKKNMIPARRYFENT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLT0</accession>
    <name>A0A1J1GLT0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00100600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526122.1">
        <property type="nucleotide sequence ID" value="XM_028672710.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLT0"/>
    <dbReference type="GeneID" id="39729530"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00100600"/>
    <dbReference type="OrthoDB" id="415460at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.50">
        <property type="entry name" value="Protein of unknown function (DUF3228), domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021610">
        <property type="entry name" value="DUF3228"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38666">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38666:SF2">
        <property type="entry name" value="FLAGELLAR ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11539">
        <property type="entry name" value="DUF3228"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="264" mass="32076" checksum="B8C6DCFB742BB5E7" modified="2017-02-15" version="1">MFKSYKLTKKYILYVLFIILFKQIRNVYMNKIRYCLKNKNFFYIKNNFFFFKEKKKIYLKKHEMDFCEVDLDEFCYKQFDKTKKSCSYIPYNKKEFIEKVNELIKEKKIKVVPGYAGFCKHIFIENFTDATIETIEINDKNRELIKTDYISRRDNELPVLIRWISKKDIKDIRKAKYLDLILYSREQIEKENKETKIVPHKKSNCLYSIICIKPQDEDYELPMTPITMLRNTLITEGGSGISLNREKYLESVKYWRHHVSIIDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLY8</accession>
    <name>A0A1J1GLY8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Mitochondrial carrier protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00104500</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526161.1">
        <property type="nucleotide sequence ID" value="XM_028673143.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLY8"/>
    <dbReference type="GeneID" id="39729570"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00104500"/>
    <dbReference type="OMA" id="CKDMCAT"/>
    <dbReference type="OrthoDB" id="250329at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015093">
        <property type="term" value="F:ferrous iron transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048250">
        <property type="term" value="P:iron import into the mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45758:SF19">
        <property type="entry name" value="CARRIER PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45758">
        <property type="entry name" value="MITOFERRIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="6"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="114"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="218"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG93339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="307" mass="36012" checksum="9F99513C96CF0E21" modified="2017-02-15" version="1">MKDNEDNILQTFLGSTFASTISRTLLYPLDTVKTNKQVHINNYKTDQNFNKNFFFSFIKKFGYKGLYKGFFFSSLTTIPATSLYFCSFEYLKLKRTNFKKKYTEKYGDENTDYLNFFDYFSLGLLAEAISCIIFVPIDVVKERMQAQKYLELKEYNKSYYLIKDLINKEGLFRLYRGYSSTCLTYGLFGGSFFFFQNIGNKLMKKLNIESSNFNIFQLNLICSFLSGLITSPLDIVRIRFQIQEKNKTLFYYNNSFDGINKLLKEGNIFNLFKGNLYRCSLVCLSMSINVTIIEMFKKIINSNTNKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM06</accession>
    <name>A0A1J1GM06_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">U5 snrnp-specific protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00116000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526276.1">
        <property type="nucleotide sequence ID" value="XM_028674422.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM06"/>
    <dbReference type="GeneID" id="39729685"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00116000"/>
    <dbReference type="OMA" id="ILYMLPG"/>
    <dbReference type="OrthoDB" id="1068471at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052234">
        <property type="entry name" value="U5_snRNP_Component"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44006">
        <property type="entry name" value="U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44006:SF1">
        <property type="entry name" value="U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="32"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="75"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="117"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="199"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="290"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="323" mass="37000" checksum="B30E556862293445" modified="2017-02-15" version="1">MAIVKSNIYTMEEEENEIKERKTGLYFPNMLINTHKGEVYSVNFSSDGRFLSSSSFDMTIMIHNVYNECETINVLRGHKNAVLQAKWSKDDSYICSASADHNLCLWDVENESKIKSFKGHTSIVNALDIINHNSFVSCSDDCTLKLWDFRCKKSIHTIKQDFPLLAVCSDKKGEFIYTSCVDNTIKVYDSKNYKLKDILTGHKDYISGLDINNDETILASISADETICFWDIQPFSCDEKLLFNLKAPKYNVDYNLIKLRFNNDNLLACGSGDNYLYIYDYKQKSLKYSLPGHHSTINDVCFHPFEEIIASCSSDHTIFLGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM62</accession>
    <name>A0A1J1GM62_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00115000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526266.1">
        <property type="nucleotide sequence ID" value="XM_028674310.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM62"/>
    <dbReference type="GeneID" id="39729675"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00115000"/>
    <dbReference type="OMA" id="QNHKLTW"/>
    <dbReference type="OrthoDB" id="359083at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056349">
        <property type="entry name" value="Microp_apicomplexa_10"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23519">
        <property type="entry name" value="Microp_apicomplexa_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="107" mass="12891" checksum="E03012AFFE5D8B6F" modified="2017-02-15" version="1">MKKIFQISKRFIYWPPKNKIRTLKFPSGKKCFIFVGKSDEDGKDEPVLCFVDNQNHKLTWMNEEEVLNFEKLMPRLDSYFSLYLEKAKKVKEQNLLLNEELNKSFHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM69</accession>
    <name>A0A1J1GM69_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SPRY domain, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00119500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526311.1">
        <property type="nucleotide sequence ID" value="XM_028674707.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM69"/>
    <dbReference type="GeneID" id="39729720"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00119500"/>
    <dbReference type="OrthoDB" id="10266026at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048188">
        <property type="term" value="C:Set1C/COMPASS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12872">
        <property type="entry name" value="SPRY_Ash2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037353">
        <property type="entry name" value="ASH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001870">
        <property type="entry name" value="B30.2/SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003877">
        <property type="entry name" value="SPRY_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10598">
        <property type="entry name" value="SET1/ASH2 HISTONE METHYLTRANSFERASE COMPLEX SUBUNIT ASH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10598:SF0">
        <property type="entry name" value="SET1_ASH2 HISTONE METHYLTRANSFERASE COMPLEX SUBUNIT ASH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00622">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00449">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50188">
        <property type="entry name" value="B302_SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B30.2/SPRY" evidence="4">
        <location>
            <begin position="272"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="81"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="81"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="520" mass="60167" checksum="50C3B557712F781B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMB5</accession>
    <name>A0A1J1GMB5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00129100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526406.1">
        <property type="nucleotide sequence ID" value="XM_028674813.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMB5"/>
    <dbReference type="GeneID" id="39729816"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00129100"/>
    <dbReference type="OMA" id="SMKETKC"/>
    <dbReference type="OrthoDB" id="364773at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="149" mass="17541" checksum="2E8C0E34595A3020" modified="2017-02-15" version="1">MNIFNICFRNFSKKAGWSWIKNRRGRKKIISITYPPKERSKIIKLTDESDKLIFVSNGKLRNNFLSIVKNMKETKCVVKNNFIITPCLVISKAKCHTLLEILTYDEILHLEKLSPCILKCFEEAEKKLDKEKENNILKKHEALKFKLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMC2</accession>
    <name>A0A1J1GMC2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00129900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526414.1">
        <property type="nucleotide sequence ID" value="XM_028674821.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729824"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00129900"/>
    <dbReference type="OMA" id="HKYEVSH"/>
    <dbReference type="OrthoDB" id="1741719at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033186">
        <property type="term" value="C:CAF-1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006335">
        <property type="term" value="P:DNA replication-dependent chromatin assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045145">
        <property type="entry name" value="PTHR15271"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15271">
        <property type="entry name" value="CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15271:SF4">
        <property type="entry name" value="CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="2123"/>
            <end position="2142"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="185"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="634"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1000"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1112"/>
            <end position="1142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1259"/>
            <end position="1291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1321"/>
            <end position="1359"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1961"/>
            <end position="1988"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="634"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="686"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="713"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="731"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="820"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="837"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="866"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1021"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1321"/>
            <end position="1337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1346"/>
            <end position="1359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2181" mass="259683" checksum="76F6C7E46A20738A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMP7</accession>
    <name>A0A1J1GMP7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00124000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526355.1">
        <property type="nucleotide sequence ID" value="XM_028674755.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMP7"/>
    <dbReference type="GeneID" id="39729765"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00124000"/>
    <dbReference type="OrthoDB" id="375095at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="441" mass="52643" checksum="11A6D64A2A901894" modified="2017-02-15" version="1">MLLVIRRNIKIFNIPKYDSEKIFKNLFLFKRKISNDINTSTQLIVKCVNEAYKSKSFSKMKWNCLSNDILKNMSNFNIKEILSIINILSHMHFGRNILIQFKSLIISKLSDLKANYILKILISYIKSNIKDDHFYNLLCLKLHNNLNTISQSSLINFLYNVNFNSNVKCDHLSNIEEQILIYLTKEFYTYNIDNKNINIECKENKNTDINESLKINEIVKKNIPEECINSNKKTLYNTKEKDETINNLKCLHLENYNFILLFYAFSHYLFNLYLKNKNNPINDNFVNQLNKYYDIIKNIINHKSKLTLLKEINSFHIFLLYKACLNTIYTFGDNSINKTLLDNIKENINNFILPLKNNNKHIKGQTNEMIRYMDILKQNLILYSENRKVHFQHYLNNNVMLIKIILSILQEKNKNDIKKYYIWHRKKVENIQKILRSIEID</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMY2</accession>
    <name>A0A1J1GMY2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transcription factor with AP2 domain(S), putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ApiAP2</name>
        <name evidence="8" type="ORF">PGAL8A_00139700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526513.1">
        <property type="nucleotide sequence ID" value="XM_028674931.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMY2"/>
    <dbReference type="GeneID" id="39729921"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00139700"/>
    <dbReference type="OrthoDB" id="371561at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00847">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="7">
        <location>
            <begin position="169"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="243"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="277" mass="33793" checksum="D5C516D3FDBF648D" modified="2017-02-15" version="1">MLNSLLLNEKYLNKSSCKNMYFNNQKILYKYFSNYLSCKIQPKSISLIFSIDKKCFGVKRVVQKRKYMLKLIQPHQEKFDIQKYRNYIEKEKLSEKININNINIDNEKEVELYENYLLNYKYNKREVEKNATLPLSLLSSSFIRRTIYSNREDVLKSLKNINWKKYCCNVKGVRWHASGAWRVLFCKRNYQHNFFVKCDCYFRVSIYGFEKSKELAVLYRKRLEYEYLLLMKRWKEIEIENAKKRKMKKESEKNNESFEDENDIGKIDNEYYNDENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMZ6</accession>
    <name>A0A1J1GMZ6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Enoyl-acyl carrier reductase, putative</fullName>
            <ecNumber evidence="9">1.3.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ENR</name>
        <name evidence="9" type="ORF">PGAL8A_00143800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.9" evidence="9"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526554.1">
        <property type="nucleotide sequence ID" value="XM_028674976.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMZ6"/>
    <dbReference type="GeneID" id="39729962"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00143800"/>
    <dbReference type="OMA" id="GLNIMFG"/>
    <dbReference type="OrthoDB" id="417891at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004318">
        <property type="term" value="F:enoyl-[acyl-carrier-protein] reductase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05372">
        <property type="entry name" value="ENR_SDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.400:FF:000001">
        <property type="entry name" value="Enoyl-[acyl-carrier-protein] reductase [NADH]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.400">
        <property type="entry name" value="Enoyl acyl carrier protein reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014358">
        <property type="entry name" value="Enoyl-ACP_Rdtase_NADH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004957">
        <property type="entry name" value="PRK06300.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43159">
        <property type="entry name" value="ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43159:SF2">
        <property type="entry name" value="ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH], CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012949829" evidence="8">
        <location>
            <begin position="21"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="390" mass="44271" checksum="8F8B9E99143E7664" modified="2017-02-15" version="1">MHKVLHNIVLIILNIYIINCFKNNASNKLNINFLVNGKNDYNKIYNRKKENVNIIRLNNAKNNENEINEQEKKVENNKDDICFIAGIGDTNGYGWGIAKELSKKNVKLIFGIWPPVYNIFMKNYQSGKFDKDMIIDNDKKMEILDILPFDASFDTYEDIDEETKNNKRYSNLKNYSIEEVSNLIHNKYGNISMLVHSLANAREVQKTLLDTSRKGYLDALSKSSYSLISLCKYFCKIMKPGSSVISLTYHASQKVVPGYGGGMSSAKAALESDTRFLAYYLGRNYKIRVNTISAGPLKSRAASAINKMNPKNMNSSGENNKENYSFIDYAIDYSEKYAPLQQKLYSTDVGSVASFLLSKESRAITGQTIYVDNGLNIMFGPDDLFQNENN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN79</accession>
    <name>A0A1J1GN79_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF4211 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00163800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526750.1">
        <property type="nucleotide sequence ID" value="XM_028675194.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN79"/>
    <dbReference type="GeneID" id="39730163"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00163800"/>
    <dbReference type="OMA" id="YDFLKMI"/>
    <dbReference type="OrthoDB" id="387164at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="411"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="523"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="418"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="429"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="523"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="543"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="996" mass="120038" checksum="4390D00F8479ED5F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNB6</accession>
    <name>A0A1J1GNB6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00166900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526782.1">
        <property type="nucleotide sequence ID" value="XM_028669985.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNB6"/>
    <dbReference type="GeneID" id="39730195"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00166900"/>
    <dbReference type="OMA" id="LKYLMSW"/>
    <dbReference type="OrthoDB" id="330493at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="384" mass="45403" checksum="0CA6E43328097DE1" modified="2017-02-15" version="1">MYNNNESSELKEKKINEINDIKEINEINEINEINDINEINEINEINEINDINDINDINDINDINDINDINDINDINDINDINDINDINEINEINEINEINDINDINEINDINIIPFCIKNILESTLGENIHNEKFLTEKNKELNTFIENNVHINVFNEEENEKNIVYDDFEFSNINNECFSNYRNKNHAIIESLNEKNSSNNSHIKPFGREKKNKKRKRNYININKLKFDFENEDFASSSNDEIVKIKYQNGNTNNNYINMENKIIKDLVEPPPIPFNENFQKFNKVVSDLYLKSKKDDETINIYLASQFLCLKEVNNFVNDNYFISDYFDKFIMKKLNIVNSSNENNIDQNKDLQELLKYLMSWYFSGFYSGKMSVLKELNKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GND8</accession>
    <name>A0A1J1GND8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Reactive oxygen species modulator 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00160100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MGR2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526714.1">
        <property type="nucleotide sequence ID" value="XM_028675154.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GND8"/>
    <dbReference type="GeneID" id="39730126"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00160100"/>
    <dbReference type="OMA" id="HKNLFIF"/>
    <dbReference type="OrthoDB" id="422939at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005744">
        <property type="term" value="C:TIM23 mitochondrial import inner membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045039">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018450">
        <property type="entry name" value="Romo1/Mgr2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28525">
        <property type="entry name" value="REACTIVE OXYGEN SPECIES MODULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28525:SF1">
        <property type="entry name" value="REACTIVE OXYGEN SPECIES MODULATOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10247">
        <property type="entry name" value="Romo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01378">
        <property type="entry name" value="Romo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="172" mass="19425" checksum="15D81F8D239E7251" modified="2017-02-15" version="1">MNWFRKKESSENKTVKSEYDDYVAPPPFGNHLAAAPEKPKFINEKNLTEFKGFTPPPKFEFKEDTSNMYDEDFSKYTNSGIVDSSAYDDKKYLSYDDKNNFFDLNLSYRTRACLESIKMGVKMGSMVGGIFGSLTGLYASFAHKNFFIFPVSVIGGAVSFGFFLGCGMIVRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNS3</accession>
    <name>A0A1J1GNS3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Iron-sulfur assembly protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00168000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526793.1">
        <property type="nucleotide sequence ID" value="XM_028669997.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNS3"/>
    <dbReference type="GeneID" id="39730206"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00168000"/>
    <dbReference type="OrthoDB" id="373638at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.600">
        <property type="entry name" value="IscX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007479">
        <property type="entry name" value="ISC_FeS_clus_asmbl_IscsX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036762">
        <property type="entry name" value="IscX-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03412">
        <property type="entry name" value="iscX_yfhJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37532">
        <property type="entry name" value="PROTEIN ISCX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37532:SF1">
        <property type="entry name" value="PROTEIN ISCX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04384">
        <property type="entry name" value="Fe-S_assembly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140319">
        <property type="entry name" value="IscX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="132" mass="15615" checksum="DE94E9C924A823E5" modified="2017-02-15" version="1">MAHNIKKYVCLVLNNFKSFSTSSYRSYGSIKYCNNNLYTSSFNSLNFNFKRFFNNNKNDVALDWENSDDIADLLFEEYKNVDPLTLRFEELENMIVDTVVNKNKKKLNGSCNESVLENIQMNWLEKYNEEND</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP60</accession>
    <name>A0A1J1GP60_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Translation initiation factor eIF2B subunit delta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">eIF2B GDP-GTP exchange factor subunit delta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00390100</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">Component of the translation initiation factor 2B (eIF2B) complex which is a heterodecamer of two sets of five different subunits: alpha, beta, gamma, delta and epsilon. Subunits alpha, beta and delta comprise a regulatory subcomplex and subunits epsilon and gamma comprise a catalytic subcomplex. Within the complex, the hexameric regulatory complex resides at the center, with the two heterodimeric catalytic subcomplexes bound on opposite sides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the eIF-2B alpha/beta/delta subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527018.1">
        <property type="nucleotide sequence ID" value="XM_028670247.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP60"/>
    <dbReference type="GeneID" id="39732431"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00390100"/>
    <dbReference type="OMA" id="CKKHSIS"/>
    <dbReference type="OrthoDB" id="10254737at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="entry name" value="Translation initiation factor eif-2b, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10233">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10233:SF14">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 12" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="137"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="195"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="808"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG94197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="965" mass="112824" checksum="145BFFE45EA4130B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP97</accession>
    <name>A0A1J1GP97_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">PPPDE peptidase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00383000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DeSI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526947.1">
        <property type="nucleotide sequence ID" value="XM_028670168.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP97"/>
    <dbReference type="GeneID" id="39732360"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00383000"/>
    <dbReference type="OrthoDB" id="412286at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0101005">
        <property type="term" value="F:deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1720.30">
        <property type="entry name" value="PPPDE domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008580">
        <property type="entry name" value="PPPDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042266">
        <property type="entry name" value="PPPDE_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12378">
        <property type="entry name" value="DESUMOYLATING ISOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12378:SF80">
        <property type="entry name" value="IP06716P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05903">
        <property type="entry name" value="Peptidase_C97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01179">
        <property type="entry name" value="DUF862"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51858">
        <property type="entry name" value="PPPDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPPDE" evidence="4">
        <location>
            <begin position="41"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="213" mass="24386" checksum="8047A9B87548B79A" modified="2017-02-15" version="1">MKKGSRENSIEHLNKEKEYNLIDYDESSEIKSIPEPDFNSNMVYLNIYDLDSVSKVVNMVARSMGAGAFHAGVEVYGYEYSFGYIVDGETGVTKTNARFHPYHVYRESIPMGKTPLTKEEVDLLVEVMKLQWIGDTYDILSRNCLNYADYFCNLLDVGSIPEWVMSLQKKVTWVKTNINVAATKIKELNKASGIPNIVKYLKKKYKENSDYEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPE3</accession>
    <name>A0A1J1GPE3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00407100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527188.1">
        <property type="nucleotide sequence ID" value="XM_028670436.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPE3"/>
    <dbReference type="GeneID" id="39732601"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00407100"/>
    <dbReference type="OMA" id="LYDSTCE"/>
    <dbReference type="OrthoDB" id="10474389at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016194">
        <property type="entry name" value="SPOC-like_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100939">
        <property type="entry name" value="SPOC domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="896" mass="107312" checksum="F0413644BF093288" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPM4</accession>
    <name>A0A1J1GPM4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">IMP1-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00094500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526061.1">
        <property type="nucleotide sequence ID" value="XM_028672032.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPM4"/>
    <dbReference type="GeneID" id="39729469"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00094500"/>
    <dbReference type="OMA" id="KTMKKDM"/>
    <dbReference type="OrthoDB" id="329578at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040785">
        <property type="entry name" value="IMP1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040955">
        <property type="entry name" value="IMP2_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18591">
        <property type="entry name" value="IMP2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18590">
        <property type="entry name" value="IMP2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Immune mapped protein 2 N-terminal" evidence="1">
        <location>
            <begin position="7"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="Immune Mapped Protein 1-like C-terminal" evidence="2">
        <location>
            <begin position="98"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="160" mass="18009" checksum="611C97AF6E2675C8" modified="2017-02-15" version="1">MSMADEKGAYLIFDSASNGSLFIVWKRERVENALMFIKPTKPVPEFKFTNHNGKSELIRNLQSDKKLFYSGLCQFIKEARDIKGEVNLLTHLDESSPIKVDIYFLKENNVLSVKVGTSFFAHEVDAVSILPKGSSSLMVKTMKKDMFVCRGNTEGASISF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ60</accession>
    <name>A0A1J1GQ60_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ATP-dependent RNA helicase prh1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00114500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526261.1">
        <property type="nucleotide sequence ID" value="XM_028674254.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ60"/>
    <dbReference type="GeneID" id="39729670"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00114500"/>
    <dbReference type="OMA" id="CTILQIH"/>
    <dbReference type="OrthoDB" id="10253254at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000390">
        <property type="term" value="P:spliceosomal complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17917">
        <property type="entry name" value="DEXHc_RHA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF85">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="4">
        <location>
            <begin position="14"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="5">
        <location>
            <begin position="269"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="612"/>
            <end position="636"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="813" mass="95325" checksum="A002BF44F7707406" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ87</accession>
    <name>A0A1J1GQ87_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">mRNA-binding protein PUF2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">PUF2</name>
        <name evidence="4" type="ORF">PGAL8A_00090600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526024.1">
        <property type="nucleotide sequence ID" value="XM_028671621.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ87"/>
    <dbReference type="GeneID" id="39729430"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00090600"/>
    <dbReference type="OMA" id="DNQFKLK"/>
    <dbReference type="OrthoDB" id="668540at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010608">
        <property type="term" value="P:post-transcriptional regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033133">
        <property type="entry name" value="PUM-HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537:SF12">
        <property type="entry name" value="MATERNAL PROTEIN PUMILIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12537">
        <property type="entry name" value="RNA BINDING PROTEIN PUMILIO-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00806">
        <property type="entry name" value="PUF"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50302">
        <property type="entry name" value="PUM"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50303">
        <property type="entry name" value="PUM_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PUM-HD" evidence="3">
        <location>
            <begin position="90"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="113"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="149"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="185"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="221"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="289"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="2">
        <location>
            <begin position="368"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="433" mass="51197" checksum="C3B28BA39B70B954" modified="2017-02-15" version="1">MGSMFFEETHFNNFKLDIQTNLNFKENLGNLKEMNSYSTNYSTPSSNIDTLYYSKNLNENNLLFLNDNEDNNLKMNENYVVNNYDLKNEKLAEFILNNNEMDEEKKVEVDLNKVMNDIFFLCFHKNGCEYIIKKLKENDNEQRQIILKSLLIDARSLCPDVYGSYVAQTIFDLKDEKYKERFTDEFLSYTSFLTLHTYGCRLIQKSLESLSDEYKCKIFKELEDDLITYICHQNGNHVIQKCVEVLPSNYIDIIIDIIEEYLPFLSSHAYGCRIVQRIYEIGNENQINRLNEKIIKKIHLIKNRYGNYVIQKCFEYSDDTVRFIITDAIVNDIYKLSAHKYACNIIEKILLKKEYKYKKKIIKKIINDISEGNENIINICKDCYGNFMMQKLLTTCRKKERNLIVKTIVGNLDKLKNETYGKYILRAINNLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQF6</accession>
    <name>A0A1J1GQF6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Large ribosomal subunit nuclear export factor, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00217000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CBF/MAK21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527588.1">
        <property type="nucleotide sequence ID" value="XM_028670880.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730697"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00217000"/>
    <dbReference type="OMA" id="FNFKEYN"/>
    <dbReference type="OrthoDB" id="371793at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005612">
        <property type="entry name" value="CCAAT-binding_factor"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03914">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="406"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="435"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="CCAAT-binding factor" evidence="4">
        <location>
            <begin position="860"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1296"/>
            <end position="1325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1309"/>
            <end position="1321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1345" mass="161840" checksum="2F0F2EF421A7E903" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQR4</accession>
    <name>A0A1J1GQR4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00200100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527419.1">
        <property type="nucleotide sequence ID" value="XM_028670692.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQR4"/>
    <dbReference type="GeneID" id="39730527"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00200100"/>
    <dbReference type="OMA" id="MYSEGEL"/>
    <dbReference type="OrthoDB" id="386973at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="205"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="237" mass="28966" checksum="95143B27260B751A" modified="2017-02-15" version="1">MHIGIKNINKNNEKRYSSMTNEEKLNLKKRIIQDGLNFSQNFSYSNFVNYQYLSLIYTKNIEELNKIEKIFEEIKFDDNKKKELIELARQKIPLFYVPLNNMYNEEELKYFESIVIPYVNKQNEITEIKKCIFNAYQNYIIYNDIFQMWSDELESLNKLIILETYQNKKKLYEDSEIHEEKKEIIHFNKIEKIKKRIKMHIAKDSKAIKENNEETQEEYKMQEEKIKKLNINIDEWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQX7</accession>
    <name>A0A1J1GQX7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Magnesium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00226400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527682.1">
        <property type="nucleotide sequence ID" value="XM_028670984.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQX7"/>
    <dbReference type="GeneID" id="39730791"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00226400"/>
    <dbReference type="OrthoDB" id="387043at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008521">
        <property type="entry name" value="Mg_trans_NIPA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12570:SF65">
        <property type="entry name" value="MAGNESIUM TRANSPORTER NIPA9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05653">
        <property type="entry name" value="Mg_trans_NIPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="511"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="534"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="566"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="606"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="637"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="682"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="740"/>
            <end position="761"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG94867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="780" mass="92460" checksum="95B229ADF1429037" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR67</accession>
    <name>A0A1J1GR67_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Serpentine receptor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00231800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527735.1">
        <property type="nucleotide sequence ID" value="XM_028671042.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR67"/>
    <dbReference type="GeneID" id="39730845"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00231800"/>
    <dbReference type="OMA" id="DLFMILN"/>
    <dbReference type="OrthoDB" id="446247at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009637">
        <property type="entry name" value="GPR107/GPR108-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21229:SF1">
        <property type="entry name" value="GH17801P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21229">
        <property type="entry name" value="LUNG SEVEN TRANSMEMBRANE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="262"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="293"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="323"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="367"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="397"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="440"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="475"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="517" mass="61808" checksum="50367395F1898706" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRA7</accession>
    <name>A0A1J1GRA7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribonuclease P protein subunit RPR2, putative</fullName>
            <ecNumber evidence="6">3.1.26.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPR2</name>
        <name evidence="6" type="ORF">PGAL8A_00239400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the eukaryotic/archaeal RNase P protein component 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.5" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527810.1">
        <property type="nucleotide sequence ID" value="XM_028671127.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRA7"/>
    <dbReference type="GeneID" id="39730922"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00239400"/>
    <dbReference type="OrthoDB" id="128536at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005655">
        <property type="term" value="C:nucleolar ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007175">
        <property type="entry name" value="Rpr2/Snm1/Rpp21"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14742:SF0">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14742">
        <property type="entry name" value="RIBONUCLEASE P SUBUNIT P21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04032">
        <property type="entry name" value="Rpr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="105"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG94997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="266" mass="31927" checksum="C7C68412E74D6209" modified="2017-02-15" version="1">MDNSKSEVKGINKNHLLKNQIKCNEIKRKLSDIYFYDEDPKNKLSSDSKIDINDKENKYERVKENNTFDNLLCEKKKFLETEKDLLKNKDIHEEMYINESCTNHSSRKKRKKKKKKSNNNTEIIKPTNQMIRINYLLQASFLMNKFNPNISREYIKTMRRFSNKFLIKYDKKFKKLFCKKCNSVLIPSVTCKVSVDPLNLQKKKIDKNEHIKDSIKKNNYFNIKSKDEYLVSYKCNYCQHNTKFVYDNNLITPQEKENFEENVHTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRH3</accession>
    <name>A0A1J1GRH3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transcription factor with AP2 domain(S), putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ApiAP2</name>
        <name evidence="9" type="ORF">PGAL8A_00254000</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527948.1">
        <property type="nucleotide sequence ID" value="XM_028671280.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731068"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00254000"/>
    <dbReference type="OrthoDB" id="333074at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2050">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00847">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="FHA" evidence="8">
        <location>
            <begin position="2018"/>
            <end position="2074"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1699"/>
            <end position="1791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2448"/>
            <end position="2494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2527"/>
            <end position="2555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2688"/>
            <end position="2714"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="3670"/>
            <end position="3699"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="3752"/>
            <end position="3786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1700"/>
            <end position="1765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1773"/>
            <end position="1791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="2448"/>
            <end position="2464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="2478"/>
            <end position="2494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="2527"/>
            <end position="2542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="2689"/>
            <end position="2706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="3673"/>
            <end position="3683"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG95135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="4017" mass="476029" checksum="2EE3A9962FBF2029" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRN7</accession>
    <name>A0A1J1GRN7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA/RNA-binding protein Alba 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00257400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histone-like Alba family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527982.1">
        <property type="nucleotide sequence ID" value="XM_028671318.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRN7"/>
    <dbReference type="GeneID" id="39731102"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00257400"/>
    <dbReference type="OMA" id="YEKEHTI"/>
    <dbReference type="OrthoDB" id="424402at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.20">
        <property type="entry name" value="Alba-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036882">
        <property type="entry name" value="Alba-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051958">
        <property type="entry name" value="Alba-like_NAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002775">
        <property type="entry name" value="DNA/RNA-bd_Alba-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13516:SF4">
        <property type="entry name" value="FI09323P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13516">
        <property type="entry name" value="RIBONUCLEASE P SUBUNIT P25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01918">
        <property type="entry name" value="Alba"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82704">
        <property type="entry name" value="AlbA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DNA/RNA-binding protein Alba-like" evidence="6">
        <location>
            <begin position="13"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="89"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="202" mass="23859" checksum="070FA6B0FA415E95" modified="2017-02-15" version="1">MSGSNKSDTKLDNEIRVSYKSDALDYVYKAIVLFETYDEVILSGVGKAISSVVNVAEMVKRRAKGIHQFTKLYEKEHIIKREDTSGLKKNTKYDNKISTEEEEDEENNKNKTTSNRIIEFSTTVPCMKIILSKNEEKIDKNEIGYQKPLDEKEINVMTPEQILKEKAYRRRYRRGRGDRGRGYRRTYYEASMWNNRRYEKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRT5</accession>
    <name>A0A1J1GRT5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00145200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526568.1">
        <property type="nucleotide sequence ID" value="XM_028674992.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRT5"/>
    <dbReference type="GeneID" id="39729976"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00145200"/>
    <dbReference type="OMA" id="IMMYSIP"/>
    <dbReference type="OrthoDB" id="10524027at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="507"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="530" mass="63097" checksum="73815DF4BED52F8F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRV0</accession>
    <name>A0A1J1GRV0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">LMBR1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00146800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526584.1">
        <property type="nucleotide sequence ID" value="XM_028675010.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRV0"/>
    <dbReference type="GeneID" id="39729992"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00146800"/>
    <dbReference type="OMA" id="KQDHIAT"/>
    <dbReference type="OrthoDB" id="73273at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31652">
        <property type="entry name" value="LIMR FAMILY PROTEIN DDB_G0283707-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31652:SF0">
        <property type="entry name" value="LIMR FAMILY PROTEIN DDB_G0283707-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="37"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="80"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="137"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="227"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="339"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="440"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="497"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="559" mass="66746" checksum="8CAE627FB32A294D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRV7</accession>
    <name>A0A1J1GRV7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00147600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526592.1">
        <property type="nucleotide sequence ID" value="XM_028675019.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRV7"/>
    <dbReference type="GeneID" id="39730000"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00147600"/>
    <dbReference type="OMA" id="YECQEWT"/>
    <dbReference type="OrthoDB" id="371488at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="496"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="650"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="496"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="506"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="936" mass="111918" checksum="3B3BF81B34A34CCA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRX7</accession>
    <name>A0A1J1GRX7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">CTLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00242800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527843.1">
        <property type="nucleotide sequence ID" value="XM_028671163.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRX7"/>
    <dbReference type="GeneID" id="39730956"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00242800"/>
    <dbReference type="OMA" id="VFCKRYK"/>
    <dbReference type="OrthoDB" id="1933455at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034657">
        <property type="term" value="C:GID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16659">
        <property type="entry name" value="RING-Ubox_Emp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024964">
        <property type="entry name" value="CTLH/CRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006595">
        <property type="entry name" value="CTLH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045098">
        <property type="entry name" value="Fyv10_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044063">
        <property type="entry name" value="ZF_RING_GID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12170:SF2">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN TRANSFERASE MAEA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12170">
        <property type="entry name" value="MACROPHAGE ERYTHROBLAST ATTACHER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10607">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00668">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50897">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51867">
        <property type="entry name" value="ZF_RING_GID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CTLH" evidence="8">
        <location>
            <begin position="447"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="RING-Gid-type" evidence="9">
        <location>
            <begin position="595"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="RING-Gid-type" evidence="6">
        <location>
            <begin position="595"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="269"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="56"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG95030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="677" mass="80122" checksum="1CB0265FC0606C53" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS47</accession>
    <name>A0A1J1GS47_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00157500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526688.1">
        <property type="nucleotide sequence ID" value="XM_028675126.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS47"/>
    <dbReference type="GeneID" id="39730100"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00157500"/>
    <dbReference type="OMA" id="YLLFHMG"/>
    <dbReference type="OrthoDB" id="10039976at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="286" mass="34675" checksum="B87F328C36B3671F" modified="2017-02-15" version="1">MENTKENNIPVINDYDSFKKSYLDVLNKKKVLYKYVFRFNNYKFKFKIISTYYEYLIICNNMLRDVTACNLFFGENLFFEMLGKSFYYPYVLYIYDLDNTYKSNVNSNNLNSLKFEKSCILDIEEIIRKGKNKNNKYFKKCNINYDRKVILNSNNINIELQNYDLKNKNIVGYIEVYLLFHMGRLFDSRIERLVVHKEYRNKCLGLIIMYICIYMLKYLYYCNRCDLNVENEIALKIYKKLRFINVETKVYRLYLHCNFNFLSGNNTVDNDKDNIQMFTENIIAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSC1</accession>
    <name>A0A1J1GSC1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ER membrane protein complex subunit 10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00016200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528204.1">
        <property type="nucleotide sequence ID" value="XM_028671564.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSC1"/>
    <dbReference type="GeneID" id="39728684"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00016200"/>
    <dbReference type="OMA" id="WIYIAIF"/>
    <dbReference type="OrthoDB" id="370020at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21203">
        <property type="entry name" value="ECM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012859634" description="ER membrane protein complex subunit 10" evidence="1">
        <location>
            <begin position="20"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="211" mass="25336" checksum="B078886755326088" modified="2017-02-15" version="1">MREKILYCIFYLFLIPVFCNKNIIELNYEINSYSLNNDKWNNIGYFILNNNEIHDTSNIYLGEKKKFIEKLKGEFDYVLFQLCYNVEEQKCIQTYVDKSRIYNIENFILLIGLDNNYLPFVMNYKTYEEYQNTKIFSGMFAIKVLSVSLPIDINNLTEENKIKTKANENMNEKEKKEPKSFLRKYWYVIVIFFISLSISKHLTENMPQTNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSG4</accession>
    <name>A0A1J1GSG4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PIR-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00266200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000035">
        <property type="protein sequence ID" value="CRG95459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528270.1">
        <property type="nucleotide sequence ID" value="XM_028671637.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSG4"/>
    <dbReference type="GeneID" id="39731191"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00266200"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="279"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="154"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="376" mass="41318" checksum="5EC35DEAF222C799" modified="2017-02-15" version="1">MLNLFLLNINLSCIDILNRKYFEIGKNNLKTELCLIRGRILAEEQQIKRSRGVRSANSIENIFKIWLESIEGEFFDELDKLTKNFTAKNAQDFLDWMHKKGGIITKTLNLSPGPDEKSFLNNTLASWEKLTEETLLNSIKDSLLHRMLSPENVTTNNNGSSITSASSNPTSSNSTSSPTPTQLYGLTTSSIYTSSVESTVSPTTALPSSSDLSPTTSSGSHINSTTSSTNDTSDLPTVLPTSGMNNSTTIMNNSTALIPPQHGGGLTSTACVGLYCAPAFAALPVSLALLGGVLVFVLLYKYTPVGKFLGRDNPKKKKAKKRLNEIPMERINSPKLLKEEKTENVKRSRLDSFLRAFGYNKKFPYIDEDVTSDQLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSL8</accession>
    <name>A0A1J1GSL8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein uL29m</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00400800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527125.1">
        <property type="nucleotide sequence ID" value="XM_028670365.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSL8"/>
    <dbReference type="GeneID" id="39732538"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00400800"/>
    <dbReference type="OMA" id="REIHQQC"/>
    <dbReference type="OrthoDB" id="270763at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038340">
        <property type="entry name" value="MRP-L47_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010729">
        <property type="entry name" value="Ribosomal_uL29_mit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21183:SF18">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL29M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21183">
        <property type="entry name" value="RIBOSOMAL PROTEIN L47, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06984">
        <property type="entry name" value="MRP-L47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="121"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="230" mass="27806" checksum="FA990304B9CF4183" modified="2017-02-15" version="1">MVFSRLNIKMNFIPKKGIEELWKNSFLDNVSMKKKLEYSKTGDAWPCVLLRKKSFDDLHKLYYICLKEKNKLLGEQYYNFQNSTKMINHGRLKKVKLTMKRILTVLSRRAIHEQCIRAKEILKKQKEREIYETQKFQLEEQLLYLKHKLNILKNTSSLEKNSLKLSMSKIENKIEQLNIILNPLRKETMHLLIPHFKYQRKYSDLPGFISWKKQNIIALRNNMSKLYRFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSM5</accession>
    <name>A0A1J1GSM5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Reticulocyte binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00269300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000039">
        <property type="protein sequence ID" value="CRG95491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528300.1">
        <property type="nucleotide sequence ID" value="XM_028671671.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731223"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00269300"/>
    <dbReference type="OMA" id="MAQMETK"/>
    <dbReference type="OrthoDB" id="386780at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009618927" evidence="3">
        <location>
            <begin position="20"/>
            <end position="2673"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2612"/>
            <end position="2632"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="952"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1238"/>
            <end position="1308"/>
        </location>
    </feature>
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        <location>
            <begin position="1348"/>
            <end position="1417"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1473"/>
            <end position="1504"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1549"/>
            <end position="1576"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1641"/>
            <end position="1718"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1778"/>
            <end position="1859"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1917"/>
            <end position="1985"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2426"/>
            <end position="2462"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2507"/>
            <end position="2588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2673" mass="313918" checksum="6B2247D898EBDB46" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSQ7</accession>
    <name>A0A1J1GSQ7_PLAGA</name>
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        <recommendedName>
            <fullName evidence="6">Sulfhydryl oxidase</fullName>
            <ecNumber evidence="6">1.8.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00378700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 R'C(R)SH + O2 = R'C(R)S-S(R)CR' + H2O2</text>
            <dbReference type="Rhea" id="RHEA:17357"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:16520"/>
            <dbReference type="ChEBI" id="CHEBI:17412"/>
            <dbReference type="EC" id="1.8.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.3.2" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526904.1">
        <property type="nucleotide sequence ID" value="XM_028670120.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSQ7"/>
    <dbReference type="GeneID" id="39732317"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00378700"/>
    <dbReference type="OMA" id="MWLQMCE"/>
    <dbReference type="OrthoDB" id="17199at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016972">
        <property type="term" value="F:thiol oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.310">
        <property type="entry name" value="ERV/ALR sulfhydryl oxidase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036774">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017905">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04777">
        <property type="entry name" value="Evr1_Alr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51324">
        <property type="entry name" value="ERV_ALR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 6" id="KW-0274">FAD</keyword>
    <keyword evidence="2 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERV/ALR sulfhydryl oxidase" evidence="8">
        <location>
            <begin position="91"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="52"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="200" mass="24436" checksum="D069B9F55B09A032" modified="2017-02-15" version="1">MGNKVPFKIFEDIYTKKSIDKSSDDRNNEIIDNCTRESLPLNIRNMEYNNIEQKEHMNNEKNTQEYTEDNENSEMEKIKKQNFYLLDESLNSNNIKHPCHAQWFLFWVFASYLNDKFSESEKEYVHSFYSYFPDQCIEGKGKNCFTEFLKIYPIRAETREELMTWLQMCENYCRKKADLPLKFFNYNKLLKRWRFDDEYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSU3</accession>
    <name>A0A1J1GSU3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="2">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00280300</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_028671797.1"/>
    </dbReference>
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    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00280300"/>
    <dbReference type="OrthoDB" id="2684236at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070530">
        <property type="term" value="F:K63-linked polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071947">
        <property type="term" value="P:protein deubiquitination involved in ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022099">
        <property type="entry name" value="DUF3638"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022105">
        <property type="entry name" value="DUF3645"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051346">
        <property type="entry name" value="OTU_Deubiquitinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13367">
        <property type="entry name" value="UBIQUITIN THIOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13367:SF28">
        <property type="entry name" value="UBIQUITIN THIOESTERASE ZRANB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12340">
        <property type="entry name" value="DUF3638"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12359">
        <property type="entry name" value="DUF3645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="DUF3638" evidence="8">
        <location>
            <begin position="3710"/>
            <end position="3853"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3645" evidence="9">
        <location>
            <begin position="4327"/>
            <end position="4358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="507"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
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            <end position="1650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
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        </location>
    </feature>
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        <location>
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            <end position="2838"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
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            <end position="4437"/>
        </location>
    </feature>
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        <location>
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            <end position="4540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
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            <end position="5007"/>
        </location>
    </feature>
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        <location>
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            <end position="5280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1608"/>
            <end position="1625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
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            <end position="1650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
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            <end position="1701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
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            <end position="1721"/>
        </location>
    </feature>
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            <end position="1742"/>
        </location>
    </feature>
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            <end position="2745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
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            <end position="2818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
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            <end position="2831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="4405"/>
            <end position="4420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="4523"/>
            <end position="4535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="4985"/>
            <end position="4998"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="5243"/>
            <end position="5280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG95606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="6254" mass="745676" checksum="67561E982CF014AD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSZ6</accession>
    <name>A0A1J1GSZ6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CERLI1-like PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00014500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528187.1">
        <property type="nucleotide sequence ID" value="XM_028671546.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSZ6"/>
    <dbReference type="GeneID" id="39728667"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00014500"/>
    <dbReference type="OMA" id="IHHINLK"/>
    <dbReference type="OrthoDB" id="391416at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056293">
        <property type="entry name" value="PH_CERLI1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23634">
        <property type="entry name" value="PH_CERLI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CERLI1-like PH" evidence="2">
        <location>
            <begin position="252"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="365"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="447" mass="54166" checksum="A028F499B1C8D094" modified="2017-02-15" version="1">MIYIDSHNLFYICSCFIGSVCTLCICKNRDLIPHISENKHIGQIYRLLNIHKYESFSIIIEIHHINLKFSEDEKSKYIIHLKIGNRYAYTHYYKEYQNKIHVEERKNMVVKQNNNILRIEVYKKGTLKNTFFGSSDIHIYNDIIKKLFPNNIYFNLVNKNQIVATISLSFHYINLNCIKKDDQIYTSLFIETIISVQKSQNKNNKKIEELINEGKEHFEAIKETDVSLNIYKNISNLAIEDKIHLFCRNLNGYLLYSNYYIKRFYYKYYFYLHFFKGKFYWCYYNDEADALVDNNRIDYIRLEYLVNVYSDVYNHKYFYIKYRKKNEKKENYLYLKTVDKDRNIWVNVIHDFIILINNYKHEKKSKKNKIKEQNKKDKKENSREMGENNNNLSHSLSMTSSIKNKYLDKKYKVDTLSNIDNEDDYRSNVDLKSIYKDMNKNMYTYSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT64</accession>
    <name>A0A1J1GT64_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Liver specific protein 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">LISP1</name>
        <name evidence="4" type="ORF">PGAL8A_00289700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528508.1">
        <property type="nucleotide sequence ID" value="XM_028671902.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731430"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00289700"/>
    <dbReference type="OMA" id="DMYSKWQ"/>
    <dbReference type="OrthoDB" id="392046at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013289336" evidence="3">
        <location>
            <begin position="22"/>
            <end position="3216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="622"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1029"/>
            <end position="1051"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="72"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="238"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="622"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="638"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="659"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1035"/>
            <end position="1051"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3216" mass="377152" checksum="928F367E7F61429D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTA1</accession>
    <name>A0A1J1GTA1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Zinc finger protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00297000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528566.1">
        <property type="nucleotide sequence ID" value="XM_028671966.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731503"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00297000"/>
    <dbReference type="OMA" id="NCENINQ"/>
    <dbReference type="OrthoDB" id="387492at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="120"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="155"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="120"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="155"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="669"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1052"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1256"/>
            <end position="1276"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="420"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1052"/>
            <end position="1064"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1065"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1262"/>
            <end position="1276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1575" mass="185488" checksum="A07714365131C6F1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTC2</accession>
    <name>A0A1J1GTC2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Leucine-rich repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00299400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the ANP32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528590.1">
        <property type="nucleotide sequence ID" value="XM_028671993.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTC2"/>
    <dbReference type="GeneID" id="39731527"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00299400"/>
    <dbReference type="OMA" id="VTNENAY"/>
    <dbReference type="OrthoDB" id="2160613at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045081">
        <property type="entry name" value="AN32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11375">
        <property type="entry name" value="ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11375:SF0">
        <property type="entry name" value="ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14580">
        <property type="entry name" value="LRR_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="199"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="199"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="245"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="281" mass="33208" checksum="4AE2C7D26CA76C4A" modified="2017-02-15" version="1">MEKAIKERVEKWKKENTVDGKEVTNENAYENLTELILDGKKFSTIKNEDKELLKKFKNLERLCLNQTGIQSLENLPKIDTLNVLELTDNHLSTIDILNFIVENFPNIKTLEIGGNHFKNIKDFEVLKNLKNLCRLGVQFNPFAEDPSYRKELFEFLPDVKIIDCYNKDGVEVLSSDEEEEEEYEEDNTLKNFYEADFKEEDEEDEEFIPNDHEEEEEDDELDDDLEEEEIDDLDKEDIDREDLDVETKESEDVEKEEKTNKRKKDSLDNTNEMDTKKTKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTC3</accession>
    <name>A0A1J1GTC3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">type I protein arginine methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.319</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PRMT1</name>
        <name evidence="9" type="ORF">PGAL8A_00297600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-arginyl-[protein] + S-adenosyl-L-methionine = N(omega)-methyl-L-arginyl-[protein] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48100"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:11990"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65280"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:48101"/>
        </physiologicalReaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.319" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528572.1">
        <property type="nucleotide sequence ID" value="XM_028671972.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTC3"/>
    <dbReference type="GeneID" id="39731509"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00297600"/>
    <dbReference type="OMA" id="QAMMEPI"/>
    <dbReference type="OrthoDB" id="7848332at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042054">
        <property type="term" value="F:histone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035242">
        <property type="term" value="F:protein-arginine omega-N asymmetric methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035241">
        <property type="term" value="F:protein-arginine omega-N monomethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.160.11:FF:000001">
        <property type="entry name" value="Blast:Protein arginine N-methyltransferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000003">
        <property type="entry name" value="Blast:Protein arginine N-methyltransferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.160.11">
        <property type="entry name" value="Hnrnp arginine n-methyltransferase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025799">
        <property type="entry name" value="Arg_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055135">
        <property type="entry name" value="PRMT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006:SF53">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22528">
        <property type="entry name" value="PRMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51678">
        <property type="entry name" value="SAM_MT_PRMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="7">
        <location>
            <begin position="121"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="Protein arginine N-methyltransferase" evidence="8">
        <location>
            <begin position="223"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF22528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG95764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="400" mass="47399" checksum="34FFB9D949A82DB7" modified="2017-02-15" version="1">MTSKYNKINKNNYETREAVYYNEENKNNCDKEKEIKDFNEKELKNFFNEWQQFYKDKINDGERKNFILLDDEKSMENGNNEYFNSYNYIHIHEDMIKDEIRTRTYYDAIRKNEHLIKDKIVLDVGSGTGILSFFAAKCGAKHVYSIEKSDIIYTALKIRDENNLTDKITFIKGLAEQIELPVDKVDIIISEWMGYCLLYENMLDTVIYCRDKWLKKGGLIFPDKAYMYIAGIEDSLYREEKFDFWKNCYDLNFSSVLPILKEEVVIDYVDKNFVVTDTCRILTLDLNTCTKDQLSFVSPFKLKMIRRDYIHALVIWFDVCFSACHTEISFTTGPFGGHTHWKQIVLYTDNIITAEKNEILKGIFALKKNKKNNRHLDMKLHYIFDGLHTRAKSIQYFNIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTF9</accession>
    <name>A0A1J1GTF9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycerophosphodiester phosphodiesterase, putative</fullName>
            <ecNumber evidence="2">3.1.4.46</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">GDPD</name>
        <name evidence="2" type="ORF">PGAL8A_00278200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.46" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528393.1">
        <property type="nucleotide sequence ID" value="XM_028671774.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTF9"/>
    <dbReference type="GeneID" id="39731315"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00278200"/>
    <dbReference type="OMA" id="NAEWAHF"/>
    <dbReference type="OrthoDB" id="1058301at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008889">
        <property type="term" value="F:glycerophosphodiester phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46211:SF14">
        <property type="entry name" value="GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46211">
        <property type="entry name" value="GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GP-PDE" evidence="1">
        <location>
            <begin position="6"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="478" mass="56485" checksum="698F4E1E04685AEE" modified="2017-02-15" version="1">MKTEKTTIVGHRGCGCSQVGGTSIYPENSLFSFKKAVDLKIDGIELDVWLTNDNEVVVIHGTNDGLIGHTLLYGEEMKGKYIEELTRKEIQSFHFKEPWILRKGKNYYIGNSNESIKFSILNENEKLEKIRDYDEFDSMYLNVEENDEIEKIINESFFNNCLTEKNNDVESDEKKREKEKKFYKEFGIDDNIEEEEFIKNIECSYCKFIYTNYLSKRTFEFKRKQVIFKFISMFYHVPLLKDILNIFKNKLTYDIELKGTKENIGLYILDILENYKGLKFKFSSFNWILQDNQIKKKLFKNKNMQKMDYSSYPYYNVEKIDLLKPLRNNKLNIPLALLFTNNEVMPNINSILCSMKYYNAEWAHFPCSLNKQSIILNCNRKDKIISVDYLVKVLHKNNKKIMIYWGAEDKDQDDDLMCYIKLNVDSICPNDIALAKEVMQKEKYINSKINEVSNNNIVNDLDTNSFLEKDEKTPLCIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTG8</accession>
    <name>A0A1J1GTG8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">rRNA 2'-O-methyltransferase fibrillarin</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Histone-glutamine methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PGAL8A_00279000</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ105me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-glutaminyl-[histone H2A] + S-adenosyl-L-methionine = N(5)-methyl-L-glutaminyl-[histone H2A] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50904"/>
            <dbReference type="Rhea" id="RHEA-COMP:12837"/>
            <dbReference type="Rhea" id="RHEA-COMP:12839"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61891"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyltransferase superfamily. Fibrillarin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528401.1">
        <property type="nucleotide sequence ID" value="XM_028671783.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTG8"/>
    <dbReference type="GeneID" id="39731323"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00279000"/>
    <dbReference type="OMA" id="HARFNGC"/>
    <dbReference type="OrthoDB" id="1859733at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031428">
        <property type="term" value="C:box C/D methylation guide snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990259">
        <property type="term" value="F:histone H2AQ104 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008649">
        <property type="term" value="F:rRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000494">
        <property type="term" value="P:box C/D sno(s)RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000001">
        <property type="entry name" value="Fibrillarin like 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000386">
        <property type="entry name" value="Fibrillarin, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00351">
        <property type="entry name" value="RNA_methyltransf_FlpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000692">
        <property type="entry name" value="Fibrillarin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020813">
        <property type="entry name" value="Fibrillarin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003276">
        <property type="entry name" value="PRK04266.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10335:SF17">
        <property type="entry name" value="FIBRILLARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10335">
        <property type="entry name" value="RRNA 2-O-METHYLTRANSFERASE FIBRILLARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01269">
        <property type="entry name" value="Fibrillarin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00052">
        <property type="entry name" value="FIBRILLARIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01206">
        <property type="entry name" value="Fibrillarin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00566">
        <property type="entry name" value="FIBRILLARIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="15">
        <location>
            <begin position="36"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="84"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00055431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="CRG95593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="328" mass="35121" checksum="1219E269B2A82114" modified="2017-02-15" version="1">MTDTFRGGLGNFKKGSNDFRRANNNSVRKGDSWKGLNGGRGGGGGRGGGGRGGGGRGGGGRGGGGRGGGGRGGGGRSGGGNRGFNKDKKNFKKDGKSGKVIVVPHRFPGVYLLKGKSDILVTKNLVPGESVYGEKRYEVMSEDDKVEYRVWNPFRSKLGACLMGGVGNMPIKPGSKVLYLGAANGTSVSHVSDMIGEEGVVYAVEFSHRSGRDLTNMSKKRSNIVPIVEDARQPIKYRMLVDMVDVVFADVAQPDQARIVALNAHMFLKTGGWFIISIKANCVDSTAKPEVVFASEMEKLKKENCKPKEKLTLEPFHRNHAIVLGVYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTK0</accession>
    <name>A0A1J1GTK0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-synthesizing GTPase</fullName>
            <ecNumber evidence="2">3.6.5.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00282200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.3" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528433.1">
        <property type="nucleotide sequence ID" value="XM_028671818.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTK0"/>
    <dbReference type="GeneID" id="39731355"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00282200"/>
    <dbReference type="OMA" id="NIGMVGH"/>
    <dbReference type="OrthoDB" id="1045173at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005850">
        <property type="term" value="C:eukaryotic translation initiation factor 2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001731">
        <property type="term" value="P:formation of translation preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01888">
        <property type="entry name" value="eIF2_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03688">
        <property type="entry name" value="eIF2_gamma_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15490">
        <property type="entry name" value="eIF2_gamma_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000009">
        <property type="entry name" value="Eukaryotic translation initiation factor 2 subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000011">
        <property type="entry name" value="Eukaryotic translation initiation factor 2 subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000065">
        <property type="entry name" value="Eukaryotic translation initiation factor 2 subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050543">
        <property type="entry name" value="eIF2G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015256">
        <property type="entry name" value="eIF2g_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044127">
        <property type="entry name" value="eIF2g_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044128">
        <property type="entry name" value="eIF2g_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003077">
        <property type="entry name" value="PRK04000.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42854">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42854:SF3">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09173">
        <property type="entry name" value="eIF2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 10" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="9">
        <location>
            <begin position="33"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG95625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="465" mass="51399" checksum="446014A206FFCDD2" modified="2017-02-15" version="1">MNINEKDKLAEQNLENLDVTKLTPLSEDVISRQATINLGTIGHVAHGKSTLVHAISGVHTVRFKHEKERNITIKLGYANAKIYKCTNPECRPPECYKSYESSKEDDPMCPRENCNHKMKLLRHVSFVDCPGHDILMATMLNGAAVMDAALLLVAGNESCPQPQTSEHLAAVEIMRLKHILILQNKVELIKEEQALKQQEEIRNFVSGTAADSAPIIPISAVLKYNIDVVCEYIVTQISIPKRDFISPPHMIVIRSFDVNKPGEDIETLQGGVAGGSILHGVLKVGDKIEIRPGIISKDEKGEITCRPIISQILTMFAENNNLKYAVPGGLIGVGTRIDPILTRADRLVGQVIGHLNKLPDCFAEIEISYYLLRRLLGVKSQDGEKNTKVAKLKNGEFLMINIGSTSIGCRVTGIKTELAKLELTGPVCTKIGDKIALSRRVDKHWRLIGWGQINKGKPLELQEPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTU5</accession>
    <name>A0A1J1GTU5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Targeted glyoxalase II, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00316300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528758.1">
        <property type="nucleotide sequence ID" value="XM_028672179.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTU5"/>
    <dbReference type="GeneID" id="39731696"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00316300"/>
    <dbReference type="OMA" id="NYAYIFY"/>
    <dbReference type="OrthoDB" id="515692at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004416">
        <property type="term" value="F:hydroxyacylglutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032282">
        <property type="entry name" value="HAGH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11935">
        <property type="entry name" value="BETA LACTAMASE DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11935:SF94">
        <property type="entry name" value="TENZING NORGAY, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16123">
        <property type="entry name" value="HAGH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="4">
        <location>
            <begin position="70"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="322" mass="38384" checksum="03ECA09587EFF27C" modified="2017-02-15" version="1">MYIKMKILKTLLSLNYFANIRYNLSTYKKLFIENGCLKKNICETDNKKKYYIINKKDICTNVIIIPLYKDNYSYIFYDNKEEGVAVDPSNYKIINEISEKENIKIKNILCTHKHYDHNSGNFFYFNKKINVYGIKENDNEYINKNLNNISNFEINNFKITTFISNFHCKNHISYLIENSRNKLKKIFFTGDFLFICGIGRNFESNNNDLYNSINNLNNLDKKNTYIFCGHEYTLDNIKFALSVDSFNNNLKSFYEKVKKDCNTPTVPSLLEEEFLYNPFLRYNDENIKKSIKNYAMKNNYVIKKNSDYLILLRIMKDNFKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU02</accession>
    <name>A0A1J1GU02_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Eukaryotic translation initiation factor 5A</fullName>
            <shortName evidence="8">eIF-5A</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00317500</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="8">eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the eIF-5A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528770.1">
        <property type="nucleotide sequence ID" value="XM_028672192.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU02"/>
    <dbReference type="GeneID" id="39731708"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00317500"/>
    <dbReference type="OMA" id="KDDVRMP"/>
    <dbReference type="OrthoDB" id="9975114at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045901">
        <property type="term" value="P:positive regulation of translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045905">
        <property type="term" value="P:positive regulation of translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04468">
        <property type="entry name" value="S1_eIF5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000007">
        <property type="entry name" value="Eukaryotic translation initiation factor 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000034">
        <property type="entry name" value="Eukaryotic translation initiation factor 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001884">
        <property type="entry name" value="IF5A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048670">
        <property type="entry name" value="IF5A-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020189">
        <property type="entry name" value="IF5A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019769">
        <property type="entry name" value="Trans_elong_IF5A_hypusine_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00037">
        <property type="entry name" value="eIF_5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11673">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR 5A FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01287">
        <property type="entry name" value="eIF-5a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21485">
        <property type="entry name" value="IF5A-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003025">
        <property type="entry name" value="eIF5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01376">
        <property type="entry name" value="eIF-5a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00302">
        <property type="entry name" value="IF5A_HYPUSINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="7 8" id="KW-0385">Hypusine</keyword>
    <keyword evidence="10" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Translation initiation factor 5A C-terminal" evidence="9">
        <location>
            <begin position="83"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG95962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="161" mass="17474" checksum="8299AC3C1B663727" modified="2017-02-15" version="1">MSDHETYDNIDAGASQTFPVQAGAIKKNGHVMLKDHPCKVVDYSTSKTGKHGHAKAHIVGIDIFTGKKYEDICPTSHNMDVPVVKRTELQLIDITEDGFVSLLHDNGETKDDLSLPKDSEGNLDDVAKQIRTLFDNGKSVLVSVLSACGQEKIIAAKELAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU11</accession>
    <name>A0A1J1GU11_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Rhodanese like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00315600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528751.1">
        <property type="nucleotide sequence ID" value="XM_028672171.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU11"/>
    <dbReference type="GeneID" id="39731689"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00315600"/>
    <dbReference type="OMA" id="INIPYHY"/>
    <dbReference type="OrthoDB" id="270167at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004792">
        <property type="term" value="F:thiosulfate-cyanide sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045078">
        <property type="entry name" value="TST/MPST-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11364:SF27">
        <property type="entry name" value="SULFURTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11364">
        <property type="entry name" value="THIOSULFATE SULFERTANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="3">
        <location>
            <begin position="140"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="3">
        <location>
            <begin position="242"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="364" mass="43708" checksum="B6E1F0D0176C6B3C" modified="2017-02-15" version="1">MKTCNFIIFSHYSNILFRSSFKSLYIFNKINNLRNYNTMKEKNNCLIETDELHSLIKNKKEYLLFDTSYYNLYPKSNEMDSDYDKIEKIKGSIPFDSRVTSNENPNFSFFFPEESEFFNYLKELLIKNQTIIGNSLENIPIIFYEKDEIFYAPRVWFMFKIFGFKNLKILNGGLNKWLCEKKEVIYEKKNNVQLKDNAKINKIKNIIEDHLKNNRDAIDNRKKNIYHYLDIKRLIESKKNKQMKNYILVDTRSNKTFSSLIQLNENKKVNNHIPFSINIPYSYFLNYHDENFKYVTFKNELEIKNIYDKYDLLNDEKIIISTCNKGVTACILLFLLHLLNKPFSKLILNQGSMVEYKYNEYNIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUI9</accession>
    <name>A0A1J1GUI9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CST complex subunit STN1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Suppressor of cdc thirteen homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00339300</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Telomere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528980.1">
        <property type="nucleotide sequence ID" value="XM_028672427.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUI9"/>
    <dbReference type="GeneID" id="39731923"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00339300"/>
    <dbReference type="OMA" id="IRAHRKD"/>
    <dbReference type="OrthoDB" id="370937at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04478">
        <property type="entry name" value="RPA2_DBD_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040260">
        <property type="entry name" value="RFA2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13989:SF33">
        <property type="entry name" value="CST COMPLEX SUBUNIT STN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13989">
        <property type="entry name" value="REPLICATION PROTEIN A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0779">Telomere</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG96175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="190" mass="22337" checksum="4FF7E33F8916CA42" modified="2017-02-15" version="1">MSGLLTNLNIESGYFNEELKEETNESNFMYTNISMLIRAYKKDRNKLMLLNKKLNLIKIVGFVINIEEKKEFIVYTIDDTTGYIKAKLLLTYSLNSYNEKKEDIKINDLIQIFGLCNTVSINEDLTISISSINKLNSFNYLCHHHLLVFHNYLKYTENEKKSLTDKTKNEYDENASVKNNDNPFFNSFFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUJ8</accession>
    <name>A0A1J1GUJ8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">WD repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00238100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527797.1">
        <property type="nucleotide sequence ID" value="XM_028671113.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUJ8"/>
    <dbReference type="GeneID" id="39730909"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00238100"/>
    <dbReference type="OMA" id="ECLFSAY"/>
    <dbReference type="OrthoDB" id="27537at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048188">
        <property type="term" value="C:Set1C/COMPASS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037867">
        <property type="entry name" value="Swd2/WDR82"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19861:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 82"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19861">
        <property type="entry name" value="WD40 REPEAT PROTEIN SWD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="340" mass="40090" checksum="A5246D160D6D74AE" modified="2017-02-15" version="1">MNEEATVNNICINEFDIYAAFENEGYISSIDLLNNIIATTNTKNIIKIYDLNERKEKLTYRIEDVVINDIKLLKRFKEKSGSIVDYDVEECLFAVYENNQKCKIYHFNIINKKIIHIFEFSNEIVDNSFVLHPNTHIFIVTLRSKELLVYHIKDKTTIYKTNIQNENCIASYNKTGIIYAYTFNVDTIYLCSCFGDDYNDEYFANFDISKITNNNNFCTHIDFSFDEKKMLIATKYNYIYTLDAYTGDILYAYNYIYESNMSHLSFFLSYPIYSFDSNFILSGGKDGYLHVWSIKGNYVCKKKIGNNIMFVKWIYNRVAFITTSNFLLIWQPSKKDENKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUR6</accession>
    <name>A0A1J1GUR6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00347300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529060.1">
        <property type="nucleotide sequence ID" value="XM_028672515.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUR6"/>
    <dbReference type="GeneID" id="39732003"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00347300"/>
    <dbReference type="OMA" id="KNTVNNH"/>
    <dbReference type="OrthoDB" id="376826at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="406"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1139" mass="135160" checksum="FC421F3C5284C8AD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUU9</accession>
    <name>A0A1J1GUU9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">H/ACA ribonucleoprotein complex subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Nucleolar protein family A member 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00350500</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Common component of the spliceosome and rRNA processing machinery.</text>
    </comment>
    <comment type="function">
        <text evidence="9">Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
            <location evidence="1 9">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the eukaryotic ribosomal protein eL8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529092.1">
        <property type="nucleotide sequence ID" value="XM_028672551.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUU9"/>
    <dbReference type="GeneID" id="39732035"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00350500"/>
    <dbReference type="OMA" id="IKNQIYA"/>
    <dbReference type="OrthoDB" id="1924699at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031429">
        <property type="term" value="C:box H/ACA snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031120">
        <property type="term" value="P:snRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.30:FF:000002">
        <property type="entry name" value="NHP2-like protein 1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050257">
        <property type="entry name" value="eL8/uL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002415">
        <property type="entry name" value="H/ACA_rnp_Nhp2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018492">
        <property type="entry name" value="Ribosomal_eL8/Nhp2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23105">
        <property type="entry name" value="RIBOSOMAL PROTEIN L7AE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00881">
        <property type="entry name" value="L7ARS6FAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00883">
        <property type="entry name" value="NUCLEARHMG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="10">
        <location>
            <begin position="39"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG96287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="145" mass="16046" checksum="2FCCE0649F9B2DE8" modified="2017-02-15" version="1">MSNTLISVENTNNSNIEEKEEEINAKIFPLASPELTNQILDIVQRATVYRQLKRGANETVKSLHKGISELVILAADAKPLEIISHIPLVCEDKNTPYVYVRSKMALGRACGISRSVIASSIITKDGSPLETQITELKDLIEQMLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVE8</accession>
    <name>A0A1J1GVE8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RBR-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00003100</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.31" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528077.1">
        <property type="nucleotide sequence ID" value="XM_028671424.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVE8"/>
    <dbReference type="GeneID" id="39728553"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00003100"/>
    <dbReference type="OMA" id="YIIESIM"/>
    <dbReference type="OrthoDB" id="10009520at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054694">
        <property type="entry name" value="Parkin-like_IBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01485">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22605">
        <property type="entry name" value="IBR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00647">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="11">
        <location>
            <begin position="187"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="392"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG95266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="562" mass="67699" checksum="EE8AA201E9EE0208" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVU7</accession>
    <name>A0A1J1GVU7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00425200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the SAP domain-containing ribonucleoprotein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529476.1">
        <property type="nucleotide sequence ID" value="XM_028672978.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVU7"/>
    <dbReference type="GeneID" id="39732784"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00425200"/>
    <dbReference type="OMA" id="KMKNYIR"/>
    <dbReference type="OrthoDB" id="445357at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052240">
        <property type="entry name" value="SAP_domain_ribonucleoprotein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46551">
        <property type="entry name" value="SAP DOMAIN-CONTAINING RIBONUCLEOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46551:SF1">
        <property type="entry name" value="SAP DOMAIN-CONTAINING RIBONUCLEOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SAP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAP" evidence="3">
        <location>
            <begin position="3"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00046328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="302" mass="35458" checksum="16F5B781021A61C9" modified="2017-02-15" version="1">MNYQNLKCSELKDLLAKRGLPSHGKKNELLERLLKYEQKDNVKSSSYIIDKNDNSINRENVELFVEEKGGIKNNNDINVKSPTKEKFDEDKNNMETNIGVKENKENKKKYISINNKEELNKGNLKKMNDYIKNILTTNNGENSKYYENDKIKNNEKTCVSKNIEDTQKEKNNFLNDNDKKSKTVIPQITFSESSLSNKNTLEKNITSKDDKDTYISEEKKRELRKKRFGFVSTDEVLESRAKRFSIITHKMEEENKRKRAERFGLNMNKLNDVETKKKRAERFGLMKESEKLKARAIRFGIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVW4</accession>
    <name>A0A1J1GVW4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Vacuolar protein-sorting-associated protein 46, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">VPS46</name>
        <name evidence="1" type="ORF">PGAL8A_00418700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529410.1">
        <property type="nucleotide sequence ID" value="XM_028672904.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVW4"/>
    <dbReference type="GeneID" id="39732718"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00418700"/>
    <dbReference type="OMA" id="DMIFQLR"/>
    <dbReference type="OrthoDB" id="10266568at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007034">
        <property type="term" value="P:vacuolar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005024">
        <property type="entry name" value="Snf7_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10476">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03357">
        <property type="entry name" value="Snf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="191" mass="21586" checksum="95B7C8C06E69FD26" modified="2017-02-15" version="1">MSTEDHIFRLKLKTKELEKLSNRSEMEEKKLISDVKKAIQSGKIDIARLYAEKCIRKKNEKVNYLNLSNKLDVLVSRLESAHRCSSLVKEVNVMIPLIQKINSETNAVKIGNDVTKLENIFDEISISSDIINDTVQTSAVISAPTEEVDELISKIAEEHAIKLDGQLGPVNAIDKHLEEMSNMSERIKNLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVX9</accession>
    <name>A0A1J1GVX9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00428400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529508.1">
        <property type="nucleotide sequence ID" value="XM_028673013.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVX9"/>
    <dbReference type="GeneID" id="39732816"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00428400"/>
    <dbReference type="OrthoDB" id="392281at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="632" mass="76353" checksum="9EE67189DE89F8E7" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWJ6</accession>
    <name>A0A1J1GWJ6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00450200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000077">
        <property type="protein sequence ID" value="CRG96921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529724.1">
        <property type="nucleotide sequence ID" value="XM_028673252.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWJ6"/>
    <dbReference type="GeneID" id="39733035"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00450200"/>
    <dbReference type="OMA" id="HETICRY"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="299"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="337" mass="39673" checksum="B2CFDCE3329CCA8C" modified="2017-02-15" version="1">MALLYNEGCPNSEEDITKCNVLACFMEGGRFSTRHCNNAFESLMLYYPFNDNSNNLTKNIFTFEHSTPAYNFQSKVTILSNNDGEILLLYEKYIHQFSYSSQKFLCRFRDKDQKLILCGKVEREYLGKTLSFNSIDIIDKKGRENYRVRLKNLENPRHISRILNYNDIFFSKDTCHYMKDGHFHETICRYSICTKDQNDHTSCVDAKLNGKLFHLQKHSQRYEGKEKFIYLPNICLSKGFKIDCTPYLCEYERPLELTPCKKLGISIVNNVIPHSESSEVKYTRTKNLVHENNLNMSSLVAMSFIPFLILFFFIGCYMYKIIKENRSRKIKMRSKEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWM5</accession>
    <name>A0A1J1GWM5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00291300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528517.1">
        <property type="nucleotide sequence ID" value="XM_028671912.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWM5"/>
    <dbReference type="GeneID" id="39731446"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00291300"/>
    <dbReference type="OMA" id="FYHQVEN"/>
    <dbReference type="OrthoDB" id="386432at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="209" mass="25715" checksum="037247E304CC52D3" modified="2017-02-15" version="1">MDIEILEEKIKKIEDEFEKLKKEESYKIEKIKNEIKLLDINTKELNKKKIMKCIECNNRSFQKKIKEKNSSSKRTKFIKDVKKEMFFELRMLKNEKEKKKTNFLNKKYKYLKIYEITNEIKHNFLELNIRRQFLFKSIIEKLTKYKNRSLHFFNKYLNIQKEINSLFELISNNALIDIFVLSKNSSFFQNQLLKNFQRFYYQVENSLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWQ1</accession>
    <name>A0A1J1GWQ1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome c oxidase assembly protein COX14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00293800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528541.1">
        <property type="nucleotide sequence ID" value="XM_028671938.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWQ1"/>
    <dbReference type="GeneID" id="39731471"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00293800"/>
    <dbReference type="OMA" id="FHMWNDA"/>
    <dbReference type="OrthoDB" id="445189at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029208">
        <property type="entry name" value="COX14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14880">
        <property type="entry name" value="COX14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="93" mass="11415" checksum="84D17E7D635E5663" modified="2017-02-15" version="1">MGVKFEFFKFFKLNYYSFYVKKEKIYTFLHTTTAYSLVGLTIYLGYSFIHMWNDAVHYSYKHYIRKEKQRKELYEKIRKARESGLIPKSEIVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX04</accession>
    <name>A0A1J1GX04_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">AARP1</name>
        <name evidence="14" type="ORF">PGAL8A_00455200</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the E3 ubiquitin-protein ligase UBR1-like family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529775.1">
        <property type="nucleotide sequence ID" value="XM_028673308.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733085"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00455200"/>
    <dbReference type="OrthoDB" id="26387at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19673">
        <property type="entry name" value="UBR-box_UBR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.110.30:FF:000002">
        <property type="entry name" value="Putative e3 ubiquitin-protein ligase ubr3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044046">
        <property type="entry name" value="E3_ligase_UBR-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003126">
        <property type="entry name" value="Znf_UBR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38924">
        <property type="entry name" value="ASPARAGINE AND ASPARTATE RICH PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38924:SF2">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_10, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18995">
        <property type="entry name" value="PRT6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02207">
        <property type="entry name" value="zf-UBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00396">
        <property type="entry name" value="ZnF_UBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51157">
        <property type="entry name" value="ZF_UBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBR-type" evidence="13">
        <location>
            <begin position="69"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="UBR-type" evidence="10">
        <location>
            <begin position="69"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="486"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1090"/>
            <end position="1179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1470"/>
            <end position="1501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1517"/>
            <end position="1558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1865"/>
            <end position="1886"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="3889"/>
            <end position="3922"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="2007"/>
            <end position="2066"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="491"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="516"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1090"/>
            <end position="1173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1482"/>
            <end position="1501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="3896"/>
            <end position="3907"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00046341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG96972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="4654" mass="553200" checksum="E9D3E63293A41F08" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX40</accession>
    <name>A0A1J1GX40_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein phosphatase PPM4, putative</fullName>
            <ecNumber evidence="3">3.1.3.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">PPM4</name>
        <name evidence="3" type="ORF">PGAL8A_00470200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529924.1">
        <property type="nucleotide sequence ID" value="XM_028673475.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX40"/>
    <dbReference type="GeneID" id="39733235"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00470200"/>
    <dbReference type="OMA" id="VCINEDI"/>
    <dbReference type="OrthoDB" id="10264738at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47992">
        <property type="entry name" value="PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="2">
        <location>
            <begin position="667"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="259"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="288"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="314"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="364"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="402"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1008" mass="117474" checksum="1E94C3FF1D5FB534" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX45</accession>
    <name>A0A1J1GX45_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">LCCL domain-containing protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">CCp3</name>
        <name evidence="14" type="ORF">PGAL8A_00278900</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528400.1">
        <property type="nucleotide sequence ID" value="XM_028671782.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX45"/>
    <dbReference type="GeneID" id="39731322"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00278900"/>
    <dbReference type="OMA" id="AGENLCG"/>
    <dbReference type="OrthoDB" id="536948at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.250.10:FF:000016">
        <property type="entry name" value="Scavenger receptor cysteine-rich protein type 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.20">
        <property type="entry name" value="LCCL-like domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.60.20">
        <property type="entry name" value="PLAT/LH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.250.10">
        <property type="entry name" value="SRCR-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051957">
        <property type="entry name" value="CRISP-LCCL_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004043">
        <property type="entry name" value="LCCL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036609">
        <property type="entry name" value="LCCL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001024">
        <property type="entry name" value="PLAT/LH2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036392">
        <property type="entry name" value="PLAT/LH2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017229">
        <property type="entry name" value="Scavenger_rcpt_PxSR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001190">
        <property type="entry name" value="SRCR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036772">
        <property type="entry name" value="SRCR-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31331:SF1">
        <property type="entry name" value="CYSTEINE RICH SECRETORY PROTEIN LCCL DOMAIN CONTAINING 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31331">
        <property type="entry name" value="LCCL DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G08630)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13385">
        <property type="entry name" value="Laminin_G_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03815">
        <property type="entry name" value="LCCL"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01477">
        <property type="entry name" value="PLAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00530">
        <property type="entry name" value="SRCR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037512">
        <property type="entry name" value="PxSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00258">
        <property type="entry name" value="SPERACTRCPTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00603">
        <property type="entry name" value="LCCL"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00308">
        <property type="entry name" value="LH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00202">
        <property type="entry name" value="SR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69848">
        <property type="entry name" value="LCCL domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49723">
        <property type="entry name" value="Lipase/lipooxygenase domain (PLAT/LH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56487">
        <property type="entry name" value="SRCR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50820">
        <property type="entry name" value="LCCL"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50095">
        <property type="entry name" value="PLAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50287">
        <property type="entry name" value="SRCR_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 10" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012723838" evidence="10">
        <location>
            <begin position="23"/>
            <end position="1255"/>
        </location>
    </feature>
    <feature type="domain" description="PLAT" evidence="11">
        <location>
            <begin position="157"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="LCCL" evidence="13">
        <location>
            <begin position="271"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="SRCR" evidence="12">
        <location>
            <begin position="398"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="SRCR" evidence="12">
        <location>
            <begin position="523"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="domain" description="LCCL" evidence="13">
        <location>
            <begin position="690"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="domain" description="LCCL" evidence="13">
        <location>
            <begin position="1063"/>
            <end position="1125"/>
        </location>
    </feature>
    <feature type="domain" description="LCCL" evidence="13">
        <location>
            <begin position="1151"/>
            <end position="1238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG95592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1255" mass="140414" checksum="8AEC7BA68A8E4E2F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX64</accession>
    <name>A0A1J1GX64_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Eukaryotic translation initiation factor 2A</fullName>
            <shortName evidence="5">eIF-2A</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00309700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the WD repeat EIF2A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528693.1">
        <property type="nucleotide sequence ID" value="XM_028672107.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX64"/>
    <dbReference type="GeneID" id="39731630"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00309700"/>
    <dbReference type="OMA" id="NIMTNKG"/>
    <dbReference type="OrthoDB" id="2194683at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011387">
        <property type="entry name" value="TIF2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013979">
        <property type="entry name" value="TIF_beta_prop-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13227">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13227:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08662">
        <property type="entry name" value="eIF2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017222">
        <property type="entry name" value="eIF2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 5 9" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Translation initiation factor beta propellor-like" evidence="8">
        <location>
            <begin position="335"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="185"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="580"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="27"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="207"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="597"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="609"/>
            <end position="627"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR017222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG95885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="627" mass="72922" checksum="889F018B4417F28D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXV8</accession>
    <name>A0A1J1GXV8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Translation initiation factor eIF2B subunit beta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">eIF2B GDP-GTP exchange factor subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00471500</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">Component of the translation initiation factor 2B (eIF2B) complex which is a heterodecamer of two sets of five different subunits: alpha, beta, gamma, delta and epsilon. Subunits alpha, beta and delta comprise a regulatory subcomplex and subunits epsilon and gamma comprise a catalytic subcomplex. Within the complex, the hexameric regulatory complex resides at the center, with the two heterodimeric catalytic subcomplexes bound on opposite sides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the eIF-2B alpha/beta/delta subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529937.1">
        <property type="nucleotide sequence ID" value="XM_028673490.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXV8"/>
    <dbReference type="GeneID" id="39733248"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00471500"/>
    <dbReference type="OMA" id="VCLNDMR"/>
    <dbReference type="OrthoDB" id="269919at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005851">
        <property type="term" value="C:eukaryotic translation initiation factor 2B complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="entry name" value="Translation initiation factor eif-2b, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051855">
        <property type="entry name" value="eIF2B_beta_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45859">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45859:SF1">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 10" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG97134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="588" mass="68252" checksum="BC0FB6171DEF58A4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXV9</accession>
    <name>A0A1J1GXV9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00305200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528648.1">
        <property type="nucleotide sequence ID" value="XM_028672057.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731585"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00305200"/>
    <dbReference type="OMA" id="DMYRLHF"/>
    <dbReference type="OrthoDB" id="377448at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013312126" evidence="2">
        <location>
            <begin position="20"/>
            <end position="1972"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="831"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1084"/>
            <end position="1111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1972" mass="241736" checksum="771994632F7A60CC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY30</accession>
    <name>A0A1J1GY30_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">hydroxymethylbilane synthase</fullName>
            <ecNumber evidence="4">2.5.1.61</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Pre-uroporphyrinogen synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00312500</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>4 porphobilinogen + H2O = hydroxymethylbilane + 4 NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57845"/>
            <dbReference type="ChEBI" id="CHEBI:58126"/>
            <dbReference type="EC" id="2.5.1.61"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 2/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the HMBS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.61" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528720.1">
        <property type="nucleotide sequence ID" value="XM_028672137.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY30"/>
    <dbReference type="GeneID" id="39731658"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00312500"/>
    <dbReference type="OMA" id="NAHEWAG"/>
    <dbReference type="OrthoDB" id="564646at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004418">
        <property type="term" value="F:hydroxymethylbilane synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006783">
        <property type="term" value="P:heme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.10:FF:000086">
        <property type="entry name" value="Probable porphobilinogen deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.40">
        <property type="entry name" value="Porphobilinogen deaminase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000860">
        <property type="entry name" value="HemC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022417">
        <property type="entry name" value="Porphobilin_deaminase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022418">
        <property type="entry name" value="Porphobilinogen_deaminase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036803">
        <property type="entry name" value="Porphobilinogen_deaminase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11557">
        <property type="entry name" value="PORPHOBILINOGEN DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11557:SF0">
        <property type="entry name" value="PORPHOBILINOGEN DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01379">
        <property type="entry name" value="Porphobil_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03900">
        <property type="entry name" value="Porphobil_deamC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00151">
        <property type="entry name" value="PORPHBDMNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54782">
        <property type="entry name" value="Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Porphobilinogen deaminase N-terminal" evidence="9">
        <location>
            <begin position="65"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="Porphobilinogen deaminase C-terminal" evidence="10">
        <location>
            <begin position="350"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00030685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG95912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="435" mass="50771" checksum="3ABDDEC0EB034806" modified="2017-02-15" version="1">MYILVFTILNIYLSIYVWGNVYIKRDNIININYLMHIRNKKLNINNLFRKNNHKKNICYIPHKEIIIGTRDSPLALKQSEKVKKKLLNHFKKINKKVKIILKPIKTTGDKILDKSVSLFGGKGIFTKELDEQLIKNNVDICVHSLKDVPMILPEDIYLPCFLKRDTINDVFLSIKYKNLNQMNKCKFNNLEKVESNIKNNFYLKKDEDKDSLCTVATSSLRRRSQIKYMYKNIELKSIRGNINTRLVKLFNGYCDSIIIALCGLERLIKRKVIVDIVKNKKRNIHKPYIIRYNNTSIDLSFLNIQKINRKFIYPALCQGIIAITSNKNNSEINDILKDINDEKSEIMGKTERAFLSQIEGNCMMPIGGYTKIVNNKIFFNAIINDIHGYEKFQIREKGEINNYLDIATNAATNIKKIIGVEKFHKIKEEAALYYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYN3</accession>
    <name>A0A1J1GYN3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00333800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528928.1">
        <property type="nucleotide sequence ID" value="XM_028672369.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731868"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00333800"/>
    <dbReference type="OMA" id="CISKIFY"/>
    <dbReference type="OrthoDB" id="377119at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012091296" evidence="2">
        <location>
            <begin position="22"/>
            <end position="1711"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="111"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1711" mass="205596" checksum="5217D4062240C668" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYT6</accession>
    <name>A0A1J1GYT6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Drug/metabolite exporter, drug/metabolite transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00520500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530430.1">
        <property type="nucleotide sequence ID" value="XM_028674037.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYT6"/>
    <dbReference type="GeneID" id="39733738"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00520500"/>
    <dbReference type="OMA" id="TALMSYY"/>
    <dbReference type="OrthoDB" id="1728340at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050638">
        <property type="entry name" value="AA-Vitamin_Transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32322">
        <property type="entry name" value="INNER MEMBRANE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32322:SF18">
        <property type="entry name" value="S-ADENOSYLMETHIONINE_S-ADENOSYLHOMOCYSTEINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="249"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="306"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="345"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="403"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="7">
        <location>
            <begin position="188"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="7">
        <location>
            <begin position="276"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="429" mass="49998" checksum="C675658A9191422F" modified="2017-02-15" version="1">MSSVLNNDNFDKDKYLVNNEKDKEKKKFLLITVNLLLLFSMLLYGINYTLMKYFIKINGSTYIFIILRTTLTIPLMVYIYITKKSKPEKKKLLSNTNEVTTKEKYKKNKYNDNDFSGIFYNSSNYDDYMKFYNNNNNNNNNNNNKDISNFMINDNISDKYNSEKYEEYYNVESFNSNYLSIISKNDEKLIPKIAHIPIIILSVAGALRQIIVIIALQYTDSHNVGIIQPTIPIFTALMSYYLKIEKMNYITFLSIFLSFIGLAITAEIWNIHALDFGFLLLLTVPVTKGLQVIYINIAAKYVSNNIIQFFQMIVLLFIALPFGILGEMLFNQKYNIINEIYNLNVNQFLCILYSTVAIIFICWKIQIIALNHLSPITVSLYQSFQPCFTFILAKIFLNETISINKIIGTVFIIMSLFLYQYGCYKKIKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYZ7</accession>
    <name>A0A1J1GYZ7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peroxisome assembly protein 22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00375300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529333.1">
        <property type="nucleotide sequence ID" value="XM_028672818.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYZ7"/>
    <dbReference type="GeneID" id="39732283"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00375300"/>
    <dbReference type="OMA" id="GQDCRKY"/>
    <dbReference type="OrthoDB" id="77656at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007031">
        <property type="term" value="P:peroxisome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037485">
        <property type="entry name" value="PEX22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34126">
        <property type="entry name" value="PEROXISOME BIOGENESIS PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34126:SF1">
        <property type="entry name" value="PEROXISOME BIOGENESIS PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22978">
        <property type="entry name" value="HAD_Pex22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="218" mass="25225" checksum="C91E794917799841" modified="2017-02-15" version="1">MPRTCKNGKDCRKYKSYDNVEDKNISLIQPIFLVGIIFMFYFFYFRIFKRRYNVNNENYRRKLNNKNKSGKPVISLCLNDIVLKINDDNVYIIENSLEAFNKLCLISELFVIAQISNDVQEKNIIELFKSLNIFNKGLKEHRLMFCTTSNGRASMIRQLSPLTHVDNDETVIKTLTGKIPNLVQIYGNLNTNDHSNFFTSLQAFTQVISAVATVEGIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ87</accession>
    <name>A0A1J1GZ87_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00034400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530707.1">
        <property type="nucleotide sequence ID" value="XM_028674345.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ87"/>
    <dbReference type="GeneID" id="39728868"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00034400"/>
    <dbReference type="OMA" id="HTQIRIK"/>
    <dbReference type="OrthoDB" id="397220at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39767">
        <property type="entry name" value="CALCIUM/CALMODULIN-BINDING MEMBRANE PROTEIN PCM4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39767:SF2">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012949809" evidence="1">
        <location>
            <begin position="19"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="268" mass="31004" checksum="E78848E7E6E607FB" modified="2017-02-15" version="1">MFWIFFLFFFFLNKKVNNENDISVKGSLTVSNLKISSKDKRESGILFMNDEMEYKLGLNTKNELIISKKNKPLINIDEHDNLNFFNPDLTVKSLNVHGVFKILNINQFQMIVHEDFSNSSNTKGWIGENFDSFTSICGGINLLGGYGKLSKGKIYKIFENIPTHTQVRIKSNFHFIDNWNNQTAYMKIGRDEKEEFFFVWTDSHSQLNKENSINICGNSTGESKFFSLIDIIVPHNSKKLIVEFGTNIQNHEPNNISWGISNFQIYII</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZB6</accession>
    <name>A0A1J1GZB6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RSE1/DDB1/CPSF1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00034600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530709.1">
        <property type="nucleotide sequence ID" value="XM_028674347.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728870"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00034600"/>
    <dbReference type="OMA" id="ILHCINS"/>
    <dbReference type="OrthoDB" id="6109at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052428">
        <property type="entry name" value="Autophagy_HostDef_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004871">
        <property type="entry name" value="RSE1/DDB1/CPSF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45971:SF5">
        <property type="entry name" value="HEPTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45971">
        <property type="entry name" value="PHOX (PX) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03178">
        <property type="entry name" value="CPSF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 C-terminal" evidence="3">
        <location>
            <begin position="1993"/>
            <end position="2175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1872"/>
            <end position="1902"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="629"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="771"/>
            <end position="810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1872"/>
            <end position="1890"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2254" mass="270150" checksum="F57E8B01FA60E5DB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZB8</accession>
    <name>A0A1J1GZB8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC transporter F family member 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ABCF1</name>
        <name evidence="11" type="ORF">PGAL8A_00522300</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530448.1">
        <property type="nucleotide sequence ID" value="XM_028674057.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZB8"/>
    <dbReference type="GeneID" id="39733756"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00522300"/>
    <dbReference type="OMA" id="VFTFYNV"/>
    <dbReference type="OrthoDB" id="10255969at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042626">
        <property type="term" value="F:ATPase-coupled transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00267">
        <property type="entry name" value="ABC_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050095">
        <property type="entry name" value="ECF_ABC_transporter_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43553:SF27">
        <property type="entry name" value="ENERGY-COUPLING FACTOR TRANSPORTER ATP-BINDING PROTEIN ECFA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43553">
        <property type="entry name" value="HEAVY METAL TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="161"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="834"/>
            <end position="1126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1237"/>
            <end position="1263"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="609"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="1253"/>
            <end position="1263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG97647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1263" mass="151484" checksum="F6C39EECFB3B51B4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZE8</accession>
    <name>A0A1J1GZE8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Non-canonical E2 ubiquitin-conjugating enzyme C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00524700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530472.1">
        <property type="nucleotide sequence ID" value="XM_028674083.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZE8"/>
    <dbReference type="GeneID" id="39733780"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00524700"/>
    <dbReference type="OMA" id="MRPRWVG"/>
    <dbReference type="OrthoDB" id="406045at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018553">
        <property type="entry name" value="E2_Ub-conjug_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057668">
        <property type="entry name" value="E2_Ub-conjug_enz_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31560">
        <property type="entry name" value="UPF0652 PROTEIN C16A11.03C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31560:SF0">
        <property type="entry name" value="UPF0652 PROTEIN C22H10.08"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09418">
        <property type="entry name" value="DUF2009"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Non-canonical E2 ubiquitin-conjugating enzyme C-terminal" evidence="1">
        <location>
            <begin position="114"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="Non-canonical E2 ubiquitin-conjugating enzyme C-terminal" evidence="1">
        <location>
            <begin position="336"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="602" mass="70739" checksum="36788BE54656A2E0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZF8</accession>
    <name>A0A1J1GZF8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00525500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530480.1">
        <property type="nucleotide sequence ID" value="XM_028674093.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZF8"/>
    <dbReference type="GeneID" id="39733788"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00525500"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000008">
        <property type="entry name" value="ATP-dependent RNA helicase RhlB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="293"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="520"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="148"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="757"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="789"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="154"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG97679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="808" mass="94250" checksum="A5AB9F5C69DE4206" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZF9</accession>
    <name>A0A1J1GZF9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00028900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530654.1">
        <property type="nucleotide sequence ID" value="XM_028674285.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728812"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00028900"/>
    <dbReference type="OMA" id="NWFDDNE"/>
    <dbReference type="OrthoDB" id="191535at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40861">
        <property type="entry name" value="DUF2183 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40861:SF1">
        <property type="entry name" value="PHOSPHATIDATE PHOSPHATASE APP1 CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1034"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1034"/>
            <end position="1062"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1375" mass="161966" checksum="DBA2D7117B923A1E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZI3</accession>
    <name>A0A1J1GZI3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphoinositide-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00044500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530811.1">
        <property type="nucleotide sequence ID" value="XM_028674461.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZI3"/>
    <dbReference type="GeneID" id="39728970"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00044500"/>
    <dbReference type="OMA" id="IICVYED"/>
    <dbReference type="OrthoDB" id="430293at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06093">
        <property type="entry name" value="PX_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1520.10">
        <property type="entry name" value="Phox-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001683">
        <property type="entry name" value="PX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036871">
        <property type="entry name" value="PX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879:SF1">
        <property type="entry name" value="CANNONBALL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00787">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00312">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64268">
        <property type="entry name" value="PX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50195">
        <property type="entry name" value="PX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="PX" evidence="2">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="499"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="815" mass="95044" checksum="E3D931BA05F1D1D4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZJ5</accession>
    <name>A0A1J1GZJ5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00033200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530694.1">
        <property type="nucleotide sequence ID" value="XM_028674330.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZJ5"/>
    <dbReference type="GeneID" id="39728855"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00033200"/>
    <dbReference type="OMA" id="NECFIFP"/>
    <dbReference type="OrthoDB" id="392450at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="431"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="539"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="572"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="637" mass="77590" checksum="63A956FAD225A712" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZQ3</accession>
    <name>A0A1J1GZQ3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fam-m protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00036700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530729.1">
        <property type="nucleotide sequence ID" value="XM_028674369.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZQ3"/>
    <dbReference type="GeneID" id="39728891"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00036700"/>
    <dbReference type="OMA" id="QISFCGI"/>
    <dbReference type="OrthoDB" id="379557at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="135" mass="16289" checksum="893C0E56C86DEBE9" modified="2017-02-15" version="1">MVLFSSIMNNKYENAKKIKEDLDIKTVEEEYIECKINNKKKKWSEKKLNSELRNLNHDIICMKKYKYYPFKKKCYNNFSFLKEGEEYYSSNEKLKKRNYKIIYENLKSSPPIQIAFCGILMTIIIGLLELKNKKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZQ6</accession>
    <name>A0A1J1GZQ6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cg3 protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00049100</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the SCO1/2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530853.1">
        <property type="nucleotide sequence ID" value="XM_028674507.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZQ6"/>
    <dbReference type="GeneID" id="39729016"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00049100"/>
    <dbReference type="OMA" id="MLYFRVE"/>
    <dbReference type="OrthoDB" id="270009at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016531">
        <property type="term" value="F:copper chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006878">
        <property type="term" value="P:intracellular copper ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02968">
        <property type="entry name" value="SCO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000013">
        <property type="entry name" value="Blast:Protein SCO1 homolog, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003782">
        <property type="entry name" value="SCO1/SenC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017276">
        <property type="entry name" value="Synth_of_cyt-c-oxidase_Sco1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12151:SF5">
        <property type="entry name" value="AT19154P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12151">
        <property type="entry name" value="ELECTRON TRANSPORT PROTIN SCO1/SENC FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02630">
        <property type="entry name" value="SCO1-SenC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037736">
        <property type="entry name" value="SCO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0186">Copper</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="12">
        <location>
            <begin position="101"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="10">
        <location>
            <begin position="139"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR037736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR037736-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR603782-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG98056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="292" mass="34406" checksum="35106B21C5B632E8" modified="2017-02-15" version="1">MNRIIKNYINNLHNIKILNYMNFDIKRSYFNVKNLKKKNFGNKLKYSTNNKEKISKKKNVFLTWKCLAFNLALTIPTLYLYILQDQKKRRNNVSKTSVQNIGKPLIGGDFTLVNQNGEIITNKSFKNKYCLIYFGFTYCPDICPQELEKQTIVIEKLRKKYGDLITPIFISVDPNRDTVAQINYYCKSFSDKLIGLTGTKELIKSVAKLFRVYYNENINNENTTNANKNDQYNYLIDHSIIHYLLDTEGQFVDFFGKNCTINEMVEKISHYLDEYLENKNKENKLHIINKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H016</accession>
    <name>A0A1J1H016_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptide chain release factor 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00060300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530965.1">
        <property type="nucleotide sequence ID" value="XM_028674631.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H016"/>
    <dbReference type="GeneID" id="39729128"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00060300"/>
    <dbReference type="OrthoDB" id="277888at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003747">
        <property type="term" value="F:translation release factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052405">
        <property type="entry name" value="Mito_Transl_Release_Factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46203:SF1">
        <property type="entry name" value="MITOCHONDRIAL TRANSLATION RELEASE FACTOR IN RESCUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46203">
        <property type="entry name" value="PROBABLE PEPTIDE CHAIN RELEASE FACTOR C12ORF65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="Release factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Prokaryotic-type class I peptide chain release factors" evidence="5">
        <location>
            <begin position="70"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG98168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="196" mass="23620" checksum="06B9E84CD3797B38" modified="2017-02-15" version="1">MYFYFLCILLYVIFFIYINSINCLTKINKDTSYISFTFRKKKIAKVFRPLCSNNLSKNNLEEIKKKLEDIGIFQKDIEEVFVKGSGKGGQKVNKTNNCVMIKYNDNLHKIIIKCHKYRYDKKCLQKNRIYARKLLYNRIFSIKDKIEKEISYQIEKEKRKTLKLTEKEKNASINYKKRKSAIKKDRQKNFKYDDII</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H075</accession>
    <name>A0A1J1H075_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">L-dopachrome isomerase</fullName>
            <ecNumber evidence="9">5.3.2.1</ecNumber>
            <ecNumber evidence="8">5.3.3.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">L-dopachrome tautomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Phenylpyruvate tautomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">MIF</name>
        <name evidence="13" type="ORF">PGAL8A_00451000</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>3-phenylpyruvate = enol-phenylpyruvate</text>
            <dbReference type="Rhea" id="RHEA:17097"/>
            <dbReference type="ChEBI" id="CHEBI:16815"/>
            <dbReference type="ChEBI" id="CHEBI:18005"/>
            <dbReference type="EC" id="5.3.2.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-dopachrome = 5,6-dihydroxyindole-2-carboxylate</text>
            <dbReference type="Rhea" id="RHEA:13041"/>
            <dbReference type="ChEBI" id="CHEBI:16875"/>
            <dbReference type="ChEBI" id="CHEBI:57509"/>
            <dbReference type="EC" id="5.3.3.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MIF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.2.1" evidence="9"/>
    <dbReference type="EC" id="5.3.3.12" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529733.1">
        <property type="nucleotide sequence ID" value="XM_028673262.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H075"/>
    <dbReference type="GeneID" id="39733043"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00451000"/>
    <dbReference type="OMA" id="CELITNI"/>
    <dbReference type="OrthoDB" id="255819at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005125">
        <property type="term" value="F:cytokine activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004167">
        <property type="term" value="F:dopachrome isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050178">
        <property type="term" value="F:phenylpyruvate tautomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.429.10">
        <property type="entry name" value="Macrophage Migration Inhibitory Factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001398">
        <property type="entry name" value="Macrophage_inhib_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014347">
        <property type="entry name" value="Tautomerase/MIF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11954">
        <property type="entry name" value="D-DOPACHROME DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11954:SF6">
        <property type="entry name" value="MACROPHAGE MIGRATION INHIBITORY FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01187">
        <property type="entry name" value="MIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55331">
        <property type="entry name" value="Tautomerase/MIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0202">Cytokine</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00036735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00036823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00041912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00042730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG96930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="116" mass="12956" checksum="2BBA3C4B53A82B66" modified="2017-02-15" version="1">MPCCELITNINVPEDSIQNTLGQLENVISAVLSKPSSYIMSNYDYQKNLRFGGSNDDFCFVRLTSIGGINKSNNSSLADKITKILQMTLNVKPRRVYVEFRDCAAQNFAFNSSLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0C8</accession>
    <name>A0A1J1H0C8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Drug metabolite transporter, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00064000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530998.1">
        <property type="nucleotide sequence ID" value="XM_028674669.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0C8"/>
    <dbReference type="GeneID" id="39729165"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00064000"/>
    <dbReference type="OMA" id="QINFTRT"/>
    <dbReference type="OrthoDB" id="29773at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13146">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13146:SF1">
        <property type="entry name" value="SUGAR PHOSPHATE TRANSPORTER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="5"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="283"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="37"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="322" mass="37359" checksum="C9480189CD441AD2" modified="2017-02-15" version="1">MKNEIIFSTTFILFLISYCFQPLLIDIIKYNGCANSSTFIFLIPHYLSMIIVGLLPKKQKLIECQWMKIFFVSLLDIVNQVLKKIGLIYAGSSLYIIIDSCTLIFTAIWRKILLNKKINNFQLLGILLITFGIAIKSNNLKIEINKEEIIGIFLIFLSNIIMGLTFVLNEKYMKQMEGQNIVCLMGLFSFCFIFIWTIIWTIPNFEHLILNNIKKKQGSIKTILLSFFFLFLFNFITSSTLWYIMKISGSLSIGILKGLKVAIIFLFSHIFFCKYDSKQCLNFHSSLSVFFCIIGVLIYSYNEYLLLATSKLYLNKKDKFIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0G8</accession>
    <name>A0A1J1H0G8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein S12, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RPS12</name>
        <name evidence="6" type="ORF">PGAL8A_API02600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <geneLocation type="apicoplast" evidence="6"/>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uS12 family.</text>
    </comment>
    <dbReference type="EMBL" id="LN835293">
        <property type="protein sequence ID" value="CRG98241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009325468.1">
        <property type="nucleotide sequence ID" value="NC_031963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0G8"/>
    <dbReference type="GeneID" id="30315805"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_API02600"/>
    <dbReference type="OMA" id="VCIRVYT"/>
    <dbReference type="OrthoDB" id="361013at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Apicoplast API"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03368">
        <property type="entry name" value="Ribosomal_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000192">
        <property type="entry name" value="Mitochondrial ribosomal protein S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006032">
        <property type="entry name" value="Ribosomal_uS12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005679">
        <property type="entry name" value="Ribosomal_uS12_bac"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00981">
        <property type="entry name" value="rpsL_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11652">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S12 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00164">
        <property type="entry name" value="Ribosom_S12_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002133">
        <property type="entry name" value="Ribosomal_S12/S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01034">
        <property type="entry name" value="RIBOSOMALS12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00055">
        <property type="entry name" value="RIBOSOMAL_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0933">Apicoplast</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00043092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG98241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="125" mass="14216" checksum="CE8077C65A7D7B92" modified="2017-02-15" version="1">MISINKLLYNKKKLNFKNKKKNNNYLLNKCPQKKGIVLKILIKTPKKPNSALRKVAKIKLSNNKELLAYIPGEGKSIQEHNFVLIKGGRVKDLPGIKYKIIRGSLDSIGVINRKTSRSKYGTKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0L5</accession>
    <name>A0A1J1H0L5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00041800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG97989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530786.1">
        <property type="nucleotide sequence ID" value="XM_028674434.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0L5"/>
    <dbReference type="GeneID" id="39728943"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00041800"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006496">
        <property type="entry name" value="CHP01606_Plasmodium_spp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09688">
        <property type="entry name" value="Wx5_PLAF3D7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="177" mass="21635" checksum="2FFE1931DBDD7AB7" modified="2017-02-15" version="1">MKTLTLYLKITTFLLFIWMYQCFFNCDSYKTLIDKSILKTKNELKYERVLTEGDTSGKKQPYAKECIEECPFDNKKKKCKNPDLYKNPYKYWYRVIIPKLWERFDKETSGMSPNKKDREWNVEWHKISTEKANDLYFVKLRRYIPYEEKKKIIDSIMEELDSRFETFLCECKIRNGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0N9</accession>
    <name>A0A1J1H0N9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00442600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529648.1">
        <property type="nucleotide sequence ID" value="XM_028673168.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0N9"/>
    <dbReference type="GeneID" id="39732959"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00442600"/>
    <dbReference type="OrthoDB" id="375854at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="98" mass="11911" checksum="38757D645C7E220C" modified="2017-02-15" version="1">MKLLINYVKKKFIRTKYRLEVIDKRYKLFSCGIPLVLLMTLTISLGTYLIDLQYKIRNKREQNINIREIKLLEEKSKLLKILRDYDCNNYENIPIKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0P6</accession>
    <name>A0A1J1H0P6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">diacylglycerol kinase (ATP)</fullName>
            <ecNumber evidence="3">2.7.1.107</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">DGK1</name>
        <name evidence="17" type="ORF">PGAL8A_00443400</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic diacylglycerol kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.107" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529656.1">
        <property type="nucleotide sequence ID" value="XM_028673177.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0P6"/>
    <dbReference type="GeneID" id="39732967"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00443400"/>
    <dbReference type="OrthoDB" id="242257at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004143">
        <property type="term" value="F:ATP-dependent diacylglycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007200">
        <property type="term" value="P:phospholipase C-activating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00029">
        <property type="entry name" value="C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20805">
        <property type="entry name" value="C1_DGK_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037607">
        <property type="entry name" value="DGK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000756">
        <property type="entry name" value="Diacylglycerol_kin_accessory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PKC_DAG/PE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11255">
        <property type="entry name" value="DIACYLGLYCEROL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11255:SF54">
        <property type="entry name" value="DIACYLGLYCEROL KINASE THETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00609">
        <property type="entry name" value="DAGK_acc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00045">
        <property type="entry name" value="DAGKa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="15">
        <location>
            <begin position="116"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="15">
        <location>
            <begin position="179"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="DAGKc" evidence="16">
        <location>
            <begin position="371"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="DAGKc" evidence="16">
        <location>
            <begin position="805"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="664"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="741"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="664"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="689"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="741"/>
            <end position="755"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="CRG96853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1181" mass="139856" checksum="3CEE242BA92C8C6E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0Y9</accession>
    <name>A0A1J1H0Y9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">6-cysteine protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00055200</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cell surface</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530914.1">
        <property type="nucleotide sequence ID" value="XM_028674575.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0Y9"/>
    <dbReference type="GeneID" id="39729077"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00055200"/>
    <dbReference type="OMA" id="NQDKECN"/>
    <dbReference type="OrthoDB" id="386449at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2860">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010884">
        <property type="entry name" value="6_CYS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038160">
        <property type="entry name" value="6_CYS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07422">
        <property type="entry name" value="s48_45"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00970">
        <property type="entry name" value="s48_45"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51701">
        <property type="entry name" value="6_CYS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012091307" evidence="9">
        <location>
            <begin position="20"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="331"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="10">
        <location>
            <begin position="15"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="10">
        <location>
            <begin position="149"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG98117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="349" mass="40737" checksum="A0C5B97C60B65242" modified="2017-02-15" version="1">MITILFIIIVLEFKKNVFCLMEKDDLILCISEYNNEKECNITTEFGKQVNLYCPTDFLKNNESIYFNKIKISNDNICFNNIMVNNDKKLKKLEELLPDIILYEGNSLHLYSFFIPHNTYENIIFSCYCIDKDKKKAFKLNVKISKNTKKVKSCNFYYSENIRKNENPSEKNLYIKHNNNCTIDGNANDTIFFQCSSNANSNFIISPLFCFHMVLDENNEETNIFGLINGAKVIPESFFYYNDNKKKKLSSYLLLPSSIQETLIIKCSCIIIDFSSSDFYSGTLFLNLEKNSSLFAYNIYNKGKTEEKINKKIPNRNNISDENEGNSILEHYSFLLTVLIFTYLYIAIYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H116</accession>
    <name>A0A1J1H116_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein-histidine N-methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.85</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00481300</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the methyltransferase superfamily. METTL18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.85" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530037.1">
        <property type="nucleotide sequence ID" value="XM_028673601.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H116"/>
    <dbReference type="GeneID" id="39733346"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00481300"/>
    <dbReference type="OMA" id="KQNIYEG"/>
    <dbReference type="OrthoDB" id="1723750at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018064">
        <property type="term" value="F:protein-L-histidine N-tele-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF39">
        <property type="entry name" value="HISTIDINE PROTEIN METHYLTRANSFERASE 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG97234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="257" mass="30477" checksum="4E95BFB84490ABA6" modified="2017-02-15" version="1">MYEVYFLNENENFEKKKKNDDEIKSSLILKNHCVDSEKKAKLVKQNIYEGGYTIWECTWDMLKFLHFEKFDFKNKNVLELGCGHGLVGIKILLDKGNVVFQELNKDVINDILLPNIKKNLNIKLKREKLKKKKNFMKIKNKGTKCFIINKKWSKLNKKLKKENLNSFDFILGNEILYRKENYYHILKILKKNLKRDGKAYFGSKSYYFGFEDGAGSNCFVDYVNNNKKFFFVARIIQTNTNKTIYSRDIIEVTFKSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1J1</accession>
    <name>A0A1J1H1J1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">DNA polymerase</fullName>
            <ecNumber evidence="20">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">PGAL8A_00476000</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="25" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="25">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="19 20">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 20">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 20">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 20">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="25">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="20"/>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529984.1">
        <property type="nucleotide sequence ID" value="XM_028673542.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1J1"/>
    <dbReference type="GeneID" id="39733293"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00476000"/>
    <dbReference type="OMA" id="CNNCRPR"/>
    <dbReference type="OrthoDB" id="2414538at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043625">
        <property type="term" value="C:delta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008296">
        <property type="term" value="F:3'-5'-DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006287">
        <property type="term" value="P:base-excision repair, gap-filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045004">
        <property type="term" value="P:DNA replication proofreading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006297">
        <property type="term" value="P:nucleotide-excision repair, DNA gap filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05777">
        <property type="entry name" value="DNA_polB_delta_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05533">
        <property type="entry name" value="POLBc_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.132.60:FF:000010">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000004">
        <property type="entry name" value="DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.60">
        <property type="entry name" value="DNA polymerase family B, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.342.10">
        <property type="entry name" value="DNA Polymerase, chain B, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.690">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017964">
        <property type="entry name" value="DNA-dir_DNA_pol_B_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006133">
        <property type="entry name" value="DNA-dir_DNA_pol_B_exonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006134">
        <property type="entry name" value="DNA-dir_DNA_pol_B_multi_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042087">
        <property type="entry name" value="DNA_pol_B_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050240">
        <property type="entry name" value="DNA_pol_type-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056435">
        <property type="entry name" value="DPOD/Z_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025687">
        <property type="entry name" value="Znf-C4pol"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00592">
        <property type="entry name" value="pol2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10322">
        <property type="entry name" value="DNA POLYMERASE CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10322:SF23">
        <property type="entry name" value="DNA POLYMERASE DELTA CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00136">
        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03104">
        <property type="entry name" value="DNA_pol_B_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24055">
        <property type="entry name" value="POL3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14260">
        <property type="entry name" value="zf-C4pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00106">
        <property type="entry name" value="DNAPOLB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00116">
        <property type="entry name" value="DNA_POLYMERASE_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 20" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 20" id="KW-0235">DNA replication</keyword>
    <keyword evidence="17 20" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="14 20" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="13" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15 20" id="KW-0408">Iron</keyword>
    <keyword evidence="16 20" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 20" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6 20 25" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="18 20" id="KW-0539">Nucleus</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 20 25" id="KW-0808">Transferase</keyword>
    <keyword evidence="12 20" id="KW-0862">Zinc</keyword>
    <keyword evidence="10 20" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNA polymerase delta/zeta catalytic subunit N-terminal" evidence="24">
        <location>
            <begin position="134"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B exonuclease" evidence="22">
        <location>
            <begin position="231"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B multifunctional" evidence="21">
        <location>
            <begin position="533"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="domain" description="C4-type zinc-finger of DNA polymerase delta" evidence="23">
        <location>
            <begin position="1000"/>
            <end position="1070"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="RuleBase" id="RU000442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF14260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF24055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="CRG97181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1091" mass="126804" checksum="6D174083DC0663F9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2B6</accession>
    <name>A0A1J1H2B6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00521900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530444.1">
        <property type="nucleotide sequence ID" value="XM_028674052.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2B6"/>
    <dbReference type="GeneID" id="39733752"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00521900"/>
    <dbReference type="OrthoDB" id="370330at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902555">
        <property type="term" value="C:endoribonuclease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038085">
        <property type="entry name" value="Rnp2-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160350">
        <property type="entry name" value="Rnp2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="148" mass="17747" checksum="CC342E1F99661BBE" modified="2017-02-15" version="1">MVKKDNIWMLCKLCYKENNEIKNENKEEDIYKILENLNIPLSSFIKEEFDKKAILLFGRIFKSILFSRFYIVFANLKLRIFIIRTSNRYKREVSLLTRFVTICDDIRVKILYSGVTLCKCKRFLKELFIKLKIEDNIPTILKELESCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2V4</accession>
    <name>A0A1J1H2V4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00025500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530620.1">
        <property type="nucleotide sequence ID" value="XM_028674248.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2V4"/>
    <dbReference type="GeneID" id="39728778"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00025500"/>
    <dbReference type="OMA" id="NMHKKNE"/>
    <dbReference type="OrthoDB" id="385064at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="15"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="225" mass="27078" checksum="9E297A69051F04E7" modified="2017-02-15" version="1">MDEKKKNFYNYVDNMHKKNEEIHKTMQIKEKLKKEEQKKIEESEEVMKKNDIYMSNVDNINKNKELSYVNLERELSIQKNKLQNLKSLLSELPDAIDKEDEKYKEFKKKSYREINELMNTLESSIGSRSIDEMWDKIKECHNNTEKLNNAIQETYSELSMLNEKYYNSKDEFRDLVELEKNKKKKLKKISVTLQFIQNLKQGVGEKTNNENDLKKKLEEINDLYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3I3</accession>
    <name>A0A1J1H3I3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ras-related protein Rab-1B, putative</fullName>
            <ecNumber evidence="6">3.6.5.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RAB1b</name>
        <name evidence="6" type="ORF">PGAL8A_00034000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.2" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530703.1">
        <property type="nucleotide sequence ID" value="XM_028674340.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3I3"/>
    <dbReference type="GeneID" id="39728864"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00034000"/>
    <dbReference type="OMA" id="TQMAKDF"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003925">
        <property type="term" value="F:G protein activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01869">
        <property type="entry name" value="Rab1_Ypt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001287">
        <property type="entry name" value="Ras-related protein Rab-1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050227">
        <property type="entry name" value="Rab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057289">
        <property type="entry name" value="Rab1/Ypt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47977">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0636">Prenylation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="200" mass="22840" checksum="7D6FABAA0C8EB536" modified="2017-02-15" version="1">MNDSYDSLFKILLIGDSGVGKSCLLLRFADDTYTDSYISTIGVDFKIKTIEIDDKIIKLQIWDTAGQERFRTITSSYYRGAQGIIIVYDVTDRDSFNNVKNWIIEIEKYASEDVQKILIGNKIDLKNDRNVSYEEGKELADSCNIQFLETSAKIAHNVEQAFKTMAYEIKNKSHLENQQKGKANINLNAKPVKDNKKKCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3L2</accession>
    <name>A0A1J1H3L2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00051400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530876.1">
        <property type="nucleotide sequence ID" value="XM_028674534.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3L2"/>
    <dbReference type="GeneID" id="39729039"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00051400"/>
    <dbReference type="OMA" id="FNTPMYQ"/>
    <dbReference type="OrthoDB" id="375936at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG98079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="113" mass="13857" checksum="65ACFF1554EC9070" modified="2017-02-15" version="1">MNFNKFNDKKRHYSMYADTNNYQISKKPSSPIINQYFYPAMPQYAYTPYNQNVNYQNMTQNCDYNYNNKRSIKKKKNFHYFNKYQNNEHTNSKESIADPWSHLYANYPNIQFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3N3</accession>
    <name>A0A1J1H3N3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RAP protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00039700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530759.1">
        <property type="nucleotide sequence ID" value="XM_028674402.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3N3"/>
    <dbReference type="GeneID" id="39728921"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00039700"/>
    <dbReference type="OMA" id="SWNNTNE"/>
    <dbReference type="OrthoDB" id="2019031at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013584">
        <property type="entry name" value="RAP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08373">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00952">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51286">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1170"/>
            <end position="1191"/>
        </location>
    </feature>
    <feature type="domain" description="RAP" evidence="3">
        <location>
            <begin position="1141"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="323"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1210" mass="143734" checksum="8CAB6646C13BB609" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKU2</accession>
    <name>A0A1J1GKU2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">50S ribosomal protein L17, apicoplast, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00069700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG92993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525815.1">
        <property type="nucleotide sequence ID" value="XM_028673198.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKU2"/>
    <dbReference type="GeneID" id="39729222"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00069700"/>
    <dbReference type="OMA" id="TTECIRH"/>
    <dbReference type="OrthoDB" id="275000at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1030.10">
        <property type="entry name" value="Ribosomal protein L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000456">
        <property type="entry name" value="Ribosomal_bL17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047859">
        <property type="entry name" value="Ribosomal_bL17_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036373">
        <property type="entry name" value="Ribosomal_bL17_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00059">
        <property type="entry name" value="L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14413:SF16">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL17M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14413">
        <property type="entry name" value="RIBOSOMAL PROTEIN L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01196">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64263">
        <property type="entry name" value="Prokaryotic ribosomal protein L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01167">
        <property type="entry name" value="RIBOSOMAL_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012113925" evidence="5">
        <location>
            <begin position="17"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG92993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="166" mass="19344" checksum="7C588D5C1A86BBF6" modified="2017-02-15" version="1">MKICILLLFICKNVLSFKIKKNVSNNFIKIKSIYKGTFYKRNITLQAHTNKNFRKLGRNASQRRALLRALTTSLLRHGKIITTEAKAKEARRKVDRIITYAKRHDNNKQYAYRLIANYVYDRELANNIVKQAPIKYKERNGGYTKITLLPKSRKGDAARMAVLELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKY9</accession>
    <name>A0A1J1GKY9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nucleotide binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00069100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AFG1 ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG92987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525809.1">
        <property type="nucleotide sequence ID" value="XM_028672532.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKY9"/>
    <dbReference type="GeneID" id="39729216"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00069100"/>
    <dbReference type="OMA" id="IHYHNFM"/>
    <dbReference type="OrthoDB" id="548867at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005654">
        <property type="entry name" value="ATPase_AFG1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF040713">
        <property type="entry name" value="ZapE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12169:SF6">
        <property type="entry name" value="AFG1-LIKE ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12169">
        <property type="entry name" value="ATPASE N2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03969">
        <property type="entry name" value="AFG1_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG92987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="628" mass="76118" checksum="98EFD3297CDA1358" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLA5</accession>
    <name>A0A1J1GLA5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00068500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG92981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525803.1">
        <property type="nucleotide sequence ID" value="XM_028671865.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLA5"/>
    <dbReference type="GeneID" id="39729210"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00068500"/>
    <dbReference type="OrthoDB" id="406314at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036838">
        <property type="entry name" value="Ribosomal_uS10_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54999">
        <property type="entry name" value="Ribosomal protein S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG92981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="325" mass="39731" checksum="30DF3ABDEC520CB3" modified="2017-02-15" version="1">MGIENYFLKYVKVTYLSRRRSEMIKTIENLKKNIYTYNNYSCKNIIYHMNEDEENFKNQFNVKIDENILNILNLINPLNLNNEKNSELPISNNINKDYNNLKENNKNISDENSINKNYLNKNIMNDKNTYILKYKINHIIGKRGKREQYRYTYLKSPFKYKYALRHYVFEKYKYHFYFYNITHFNINIIFNIILSSMTSNTSVKCNINWFYPGDNLFDSMFFRKSFNIFIENNIKSSIMNSNIKNQMEELKNLEERNKLEHHFYDINLDLNKYNIQDLLPLFLENKLFSENYKKLILLEEKSFKQMKKKIRKKNVHWFLNKNPNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLV1</accession>
    <name>A0A1J1GLV1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">General transcription factor TFIIB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00106600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526183.1">
        <property type="nucleotide sequence ID" value="XM_028673388.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLV1"/>
    <dbReference type="GeneID" id="39729592"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00106600"/>
    <dbReference type="OrthoDB" id="25790at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097550">
        <property type="term" value="C:transcription preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070897">
        <property type="term" value="P:transcription preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000812">
        <property type="entry name" value="TFIIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013150">
        <property type="entry name" value="TFIIB_cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013137">
        <property type="entry name" value="Znf_TFIIB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618:SF13">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00382">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08271">
        <property type="entry name" value="Zn_Ribbon_TF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00685">
        <property type="entry name" value="TIFACTORIIB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51134">
        <property type="entry name" value="ZF_TFIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIB-type" evidence="7">
        <location>
            <begin position="42"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="160"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="366" mass="41943" checksum="634C38BC4078A19C" modified="2017-02-15" version="1">MSSTYNKKLALNSVNDKPVPLNINTNNENNNIKRKIYRSFRNTRNAFCPDCKEKGIIICDNSEGTQICNGCGLVVESNILSDEQEWRNFNNDGHSKGNDRNRVGEVSDIWLENNLTSTTFIKSSKKLQHLNMMTQINKNDQTLIAAFNILKLICETFFLRSNVIERAKEITKELQDLEQLKNRINNLNMLAVVYLACREAGHIKSIKELITFDRSYKEKDLGKTINKLKKVLPTRAFVYNENISHLIYTLSNRLQLSTDLIEAIEYVVKKATTLITTSHRLNSLCGGSIHLIVELNTNEEKNIKLPNLSQIASVCGVTTNTLKTTFKELLNASEYILPKYYLTENNQKLSLLKQKYISEEKKKKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLV2</accession>
    <name>A0A1J1GLV2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">4-hydroxy-3-methylbut-2-enyl diphosphate reductase</fullName>
            <ecNumber evidence="7">1.17.7.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00100500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the IspH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.7.4" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526121.1">
        <property type="nucleotide sequence ID" value="XM_028672699.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLV2"/>
    <dbReference type="GeneID" id="39729529"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00100500"/>
    <dbReference type="OMA" id="ICTECDI"/>
    <dbReference type="OrthoDB" id="1698201at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051745">
        <property type="term" value="F:4-hydroxy-3-methylbut-2-enyl diphosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050992">
        <property type="term" value="P:dimethylallyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13944">
        <property type="entry name" value="lytB_ispH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.20">
        <property type="entry name" value="4-hydroxy-3-methylbut-2-enyl diphosphate reductase, catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00191">
        <property type="entry name" value="IspH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003451">
        <property type="entry name" value="LytB/IspH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00216">
        <property type="entry name" value="ispH_lytB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30426">
        <property type="entry name" value="4-HYDROXY-3-METHYLBUT-2-ENYL DIPHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30426:SF0">
        <property type="entry name" value="4-HYDROXY-3-METHYLBUT-2-ENYL DIPHOSPHATE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02401">
        <property type="entry name" value="LYTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00046335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="478" mass="54968" checksum="9A9EEB5DA64CBDC0" modified="2017-02-15" version="1">MYYVLFYLFKKFSPHYIPCSKYSLKFFHIFFFKCLIILLNANIIKYTMKNPLKLLETPSKIPMAIWKVRNIGTFKTYKKNDVKLLNYTFLYYNLKFNNSRTFQNAGFFSERKLSSNSKFSEETNVKVMCKKIDGQETNSIINENNNMDKGLENISSDEKILYLVNPRGFCKGVSRAIETVEECLKLFNTQIYVKHKIVHNDIVCRDLEKKGAIFIEDLNEVPDGSILIYSAHGISPQIRELAKKKKLFEIDATCPLVNKVHVYVQVKAKEGYKIILIGHKNHVEVIGTYNEAPECTFIVENVKDVENLNFPKDEKLFYVTQTTLSMDDCALIVKKLKEKYPQILTIPSGSICYATTNRQQALNQICTECDLTIVVGSQSSSNAKKLVYSSQIRNVPSLLVNTVDEFNFDILKNVKKIALTSAASTPEEETQKFVQVLTAPPFIYKLKIFDGVKENVPKWKLPKNLLDFIKGKKQNETN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLW7</accession>
    <name>A0A1J1GLW7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine protein kinase, FIKK family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00108200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526199.1">
        <property type="nucleotide sequence ID" value="XM_028673566.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLW7"/>
    <dbReference type="GeneID" id="39729608"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00108200"/>
    <dbReference type="OMA" id="CEEAHIV"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044773">
        <property type="term" value="P:mitotic DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000505">
        <property type="entry name" value="Serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167">
        <property type="entry name" value="OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44167:SF24">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE CHK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="851"/>
            <end position="1214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1218" mass="143578" checksum="10C78D43F6E0E4E5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLY1</accession>
    <name>A0A1J1GLY1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00103700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526153.1">
        <property type="nucleotide sequence ID" value="XM_028673054.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLY1"/>
    <dbReference type="GeneID" id="39729562"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00103700"/>
    <dbReference type="OrthoDB" id="10445285at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="845"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="885"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="949"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1018"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1044"/>
            <end position="1068"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1167" mass="142235" checksum="9B365118F88761EF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM23</accession>
    <name>A0A1J1GM23_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">AN1-like zinc finger, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00099100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526107.1">
        <property type="nucleotide sequence ID" value="XM_028672544.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM23"/>
    <dbReference type="GeneID" id="39729515"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00099100"/>
    <dbReference type="OrthoDB" id="431929at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1110.10">
        <property type="entry name" value="AN1-like Zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035896">
        <property type="entry name" value="AN1-like_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000058">
        <property type="entry name" value="Znf_AN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14677">
        <property type="entry name" value="ARSENITE INDUCUBLE RNA ASSOCIATED PROTEIN AIP-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14677:SF20">
        <property type="entry name" value="ZINC FINGER AN1-TYPE CONTAINING 2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01428">
        <property type="entry name" value="zf-AN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00154">
        <property type="entry name" value="ZnF_AN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118310">
        <property type="entry name" value="AN1-like Zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="AN1-type" evidence="4">
        <location>
            <begin position="9"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="339" mass="40118" checksum="DB703DB51146E864" modified="2017-02-15" version="1">MKHEIDKQCSYDYCKINDFLPFLCRYCKKFFCINHQNAEDHECIDYLEIKNKIRICDDKKIAIKNDKDLYVVCEKCKALIKIDENENRYENSFINNVKEIYEKHEINECKNNVISPKYCSFNECIYNKYCINSNNNRKCIICQKIFCFNHVNAVNHNCEEMKKKMNLKKEEIKLKFQKRISSNTSSTVRDNIKSEIVNDTSNEKKKKLEEKIFRIKIKLTSIGLTSISESSRIFVKLIIDNSLIIIKNSFQIEKKTCMFKNRSVNIWLNGDITIGNNIELLSEIFKAVIFSKNENNFFLYKILKYRDGKLAFNDNELYFLDCSSFCRNVLSDGDTILIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMC0</accession>
    <name>A0A1J1GMC0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00125200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526367.1">
        <property type="nucleotide sequence ID" value="XM_028674769.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMC0"/>
    <dbReference type="GeneID" id="39729777"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00125200"/>
    <dbReference type="OMA" id="CGNINCI"/>
    <dbReference type="OrthoDB" id="408098at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="191" mass="22015" checksum="7A00AFCE028828D0" modified="2017-02-15" version="1">MDIFNCQYCSISPFDYILDYIYGERSSKKDEKKNSNVTYDDSSSNNVSQVVSKFGEQIEKRSTNEILLLCRAWENYVHPRAKEYWKDSHQLQNILCKIANGITKNDDPILGDDYACVFWYGDKNKNDNCPIISVKKGNDSVETITYVNRVLIFLYADEASFQELQKKPKKAFTMACGNINCINLTHISLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GML9</accession>
    <name>A0A1J1GML9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">S1 motif domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00120800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526323.1">
        <property type="nucleotide sequence ID" value="XM_028674720.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729733"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00120800"/>
    <dbReference type="OMA" id="EKMYYYF"/>
    <dbReference type="OrthoDB" id="372464at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012859622" description="S1 motif domain-containing protein" evidence="3">
        <location>
            <begin position="17"/>
            <end position="1545"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="4">
        <location>
            <begin position="130"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="4">
        <location>
            <begin position="420"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="811"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="229"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="620"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="811"/>
            <end position="861"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1545" mass="185853" checksum="6BEC1F54D779EAE0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMN3</accession>
    <name>A0A1J1GMN3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cytosolic fatty-acid binding proteins domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00140000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526516.1">
        <property type="nucleotide sequence ID" value="XM_028674935.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMN3"/>
    <dbReference type="GeneID" id="39729924"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00140000"/>
    <dbReference type="OMA" id="INRCIPK"/>
    <dbReference type="OrthoDB" id="390748at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="371" mass="43932" checksum="96C2BD2380AC397B" modified="2017-02-15" version="1">MKKENNYIKDDDNFQVLIKQICNELKKRDKNKNGLMLYNSFIEVMDMFQIEYGSHIIDYLMKHCSVTEDGFVNYKNLLLIHDPSKTVRNNSECIAESINPKFIHVQDKCEDIDKSMQKKNEIIRKLYAQWDKCLLKDEEFKNKLIEANIDITPEFERALYLYGPSRSLSFANVMKTLYINNCRNRKNRNNFINKIKDEKWRKLNVDENTQCFQEPNRNPIAWEEPNIIDADNLIENVEVISKYLNGEENFNLNKEIISKDFFNNTVKNLIKNYIANKISEKEFYLYLSKLNISITQELNNLIKYHESDSNGKFKDFATIIHRCIPRNITHNLQTNVESAEVGRNNKHTNLNFTFNNFHSNNLSSDNFNDNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GND4</accession>
    <name>A0A1J1GND4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Choline/ethanolaminephosphotransferase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CEPT</name>
        <name evidence="7" type="ORF">PGAL8A_00156800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526681.1">
        <property type="nucleotide sequence ID" value="XM_028675118.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GND4"/>
    <dbReference type="GeneID" id="39730093"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00156800"/>
    <dbReference type="OMA" id="SVYANCK"/>
    <dbReference type="OrthoDB" id="196717at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016780">
        <property type="term" value="F:phosphotransferase activity, for other substituted phosphate groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048254">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014472">
        <property type="entry name" value="CHOPT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10414:SF37">
        <property type="entry name" value="BB IN A BOXCAR, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10414">
        <property type="entry name" value="ETHANOLAMINEPHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="164"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="244"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="297" mass="34387" checksum="778D56A032E4B784" modified="2017-02-15" version="1" fragment="single">TFDAIDGKQARRTNTSSPLGQLFDHGCDSITSSLFIFIVGKVADLPKGLIYYILLSSIQLQTYLFSWVEYHTRVYNTSIGRFGITEAHVIVISICILRGIKGVGIFNTTVNDILPENIRKFLCEYMLGVKLNYLILIPVSFFILLTISRSIYMGLQHAKKKREALSQLAIFYIFVFIQYYFYKSPLTVKHELICFLIISLYSSVYTLHMNLSSVLKIQMELFPSPTIFYYISILVLLLKQSTNYQFLTIFIFKDIFILSCMLIFIIIYLLDYANTIISNVCRELNINFLFNKKIKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNZ9</accession>
    <name>A0A1J1GNZ9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MerC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00071100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525829.1">
        <property type="nucleotide sequence ID" value="XM_028674701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNZ9"/>
    <dbReference type="GeneID" id="39729236"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00071100"/>
    <dbReference type="OMA" id="CCEMKGR"/>
    <dbReference type="OrthoDB" id="45840at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="198" mass="22985" checksum="1DDE0DE2AAB692DF" modified="2017-02-15" version="1">MIKITKLSLNRISSIASIICLIDCTLIPILMFTLSIFNIVDYEIVYFNHLSDILALFVMAPICSLCIIFNYYQLKNVLLLLWGVFGIILFTISHGHFSINEKINIFLQKFHIIISLFSILILLSNNYVSQKILKKNNLDNCCFTKNNEKNENGQKYAYHINVNCSNLSSDYNKSSLNYENKNYKKFDKTENELVSFLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP38</accession>
    <name>A0A1J1GP38_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fam-h protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00177200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526881.1">
        <property type="nucleotide sequence ID" value="XM_028670095.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP38"/>
    <dbReference type="GeneID" id="39730299"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00177200"/>
    <dbReference type="OMA" id="NYRTWND"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022139">
        <property type="entry name" value="Fam-L/Fam-M-like_plasmodium"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12420">
        <property type="entry name" value="DUF3671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="106"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="230" mass="26952" checksum="B919AEAB59E3C0BF" modified="2017-02-15" version="1">MRDYINSNIILNSRCNSHTEENFVIEDISTLKKYRTRGKINKLFFFIKISLFTLLIWILLYCENYNYRTWNDKYNLKNKLDLGTKRSLSEGKEVIEPTNEELKVSSSNIQTNLEENNTKVEKLELKEEEKDKKEIIKIENENENVVQIKRESNNKVNSLHLMQKYKKILRIFNIASIVLLPLMSMTLSIVSLTTTDKENKYVNGSNIVTSLYLVLNSILLLDLKSNSNNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP57</accession>
    <name>A0A1J1GP57_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-editing substrate-binding complex 6 protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00077000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525885.1">
        <property type="nucleotide sequence ID" value="XM_028670077.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP57"/>
    <dbReference type="GeneID" id="39729295"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00077000"/>
    <dbReference type="OrthoDB" id="293274at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058917">
        <property type="entry name" value="RESC6_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26188">
        <property type="entry name" value="RESC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA-editing substrate-binding complex 6 protein" evidence="1">
        <location>
            <begin position="270"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF26188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="838" mass="99392" checksum="83C74D65BE58DCA4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP74</accession>
    <name>A0A1J1GP74_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00380600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526923.1">
        <property type="nucleotide sequence ID" value="XM_028670141.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP74"/>
    <dbReference type="GeneID" id="39732336"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00380600"/>
    <dbReference type="OMA" id="FSRDRYY"/>
    <dbReference type="OrthoDB" id="1099063at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12339">
        <property type="entry name" value="RRM2_SRSF1_4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050502">
        <property type="entry name" value="Euk_RNA-bind_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48025">
        <property type="entry name" value="OS02G0815200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48025:SF1">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="227"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="332"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="471"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="471"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="500"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="844"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="927"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="982"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="995"/>
            <end position="1012"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1055" mass="130543" checksum="56184405806728EB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP87</accession>
    <name>A0A1J1GP87_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">CPSF (Cleavage and polyadenylation specific factor), subunit A, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00398600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527103.1">
        <property type="nucleotide sequence ID" value="XM_028670341.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732516"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00398600"/>
    <dbReference type="OMA" id="FRENNAC"/>
    <dbReference type="OrthoDB" id="6109at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018846">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058543">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050358">
        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004871">
        <property type="entry name" value="RSE1/DDB1/CPSF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10433">
        <property type="entry name" value="Beta-prop_RSE1_1st"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23726">
        <property type="entry name" value="Beta-prop_RSE1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03178">
        <property type="entry name" value="CPSF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="2223"/>
            <end position="2242"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 first beta-propeller" evidence="7">
        <location>
            <begin position="15"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 first beta-propeller" evidence="7">
        <location>
            <begin position="437"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 second beta-propeller" evidence="8">
        <location>
            <begin position="1010"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 C-terminal" evidence="6">
        <location>
            <begin position="1971"/>
            <end position="2328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="215"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1679"/>
            <end position="1698"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="1713"/>
            <end position="1740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="248"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF23726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2370" mass="280027" checksum="A444A5CEA9E3000B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPF3</accession>
    <name>A0A1J1GPF3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lysine decarboxylase-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00087100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525989.1">
        <property type="nucleotide sequence ID" value="XM_028671233.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPF3"/>
    <dbReference type="GeneID" id="39729395"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00087100"/>
    <dbReference type="OMA" id="QQLVYCP"/>
    <dbReference type="OrthoDB" id="414463at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031100">
        <property type="entry name" value="LOG_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052341">
        <property type="entry name" value="LOG_family_nucleotidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43393">
        <property type="entry name" value="CYTOKININ RIBOSIDE 5'-MONOPHOSPHATE PHOSPHORIBOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43393:SF3">
        <property type="entry name" value="LYSINE DECARBOXYLASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03641">
        <property type="entry name" value="Lysine_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102405">
        <property type="entry name" value="MCP/YpsA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="72"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="334" mass="38377" checksum="CD0A5800D1629A72" modified="2017-02-15" version="1">MEKECESIKSDIDGEENEIEINEIYNKSSFINSRGARLIRIMSEFVGVQDALKDEGIFFTVVVFGSSRSLSKEKYESKKNDLEKKLENFNEKIKSNIELVDEELKEYNHIKKELEDLEKLKWTIEFYKKIYELSKMLTFFFSTDEGQKAVNNISSHLPKVHNFLPNKKEQKTPNIFTVAICTGGGPGFMEAANKGSKDAGGKSIGFMISLPFEKGANPYVDKSLSFKFHYFFTRKFWLVYLSLAFIILPGGFGTLDEMMEILTLKQCKKFKRDVPIVLLGKQFWFDVLNFQKLVDYGVISQTDLDSIFITDCVDEAYNFVISHLKNTPCLSNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPF8</accession>
    <name>A0A1J1GPF8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Replication factor C subunit 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00408700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the activator 1 small subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527204.1">
        <property type="nucleotide sequence ID" value="XM_028670453.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPF8"/>
    <dbReference type="GeneID" id="39732617"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00408700"/>
    <dbReference type="OMA" id="GATKYIQ"/>
    <dbReference type="OrthoDB" id="4199794at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005663">
        <property type="term" value="C:DNA replication factor C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18140">
        <property type="entry name" value="HLD_clamp_RFC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000952">
        <property type="entry name" value="Replication factor C subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050238">
        <property type="entry name" value="DNA_Rep/Repair_Clamp_Loader"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013748">
        <property type="entry name" value="Rep_factorC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047854">
        <property type="entry name" value="RFC_lid"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001679">
        <property type="entry name" value="PRK00440.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669">
        <property type="entry name" value="REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11669:SF20">
        <property type="entry name" value="REPLICATION FACTOR C SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21960">
        <property type="entry name" value="RCF1-5-like_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08542">
        <property type="entry name" value="Rep_fac_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="5">
        <location>
            <begin position="36"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG94383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="331" mass="37955" checksum="9081753E6FEC930D" modified="2017-02-15" version="1">MDNLPWVEKYRPKKLDDIVHQSNAVRMLKEVVKTKNMPHLIFHGPPGTGKTSAINALAHELFGKDNIKDRVLELNASDDRGINIVREKIKAYTRISISKNKINNETNETLPSWKLVVLDEADMMTDDAQSALRRIIEIYSNVTRFILICNYIHKISDPIFSRCSCYRFQSIPINIKKEKLLYICKSENINITDDALEKIIETTQGDLRRAVSILQLCSCINPQITLESVLDVSGLPNDNIILKIIDACKMKDLKNVEKTVQDIIEDGFDVSYIFKAFNNYFVTNSDYQDSLKYQILLELSRHDYRLHSGATQYIQLLSFAVKIHSLLNSIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPI8</accession>
    <name>A0A1J1GPI8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Rab3-GAP regulatory subunit N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00392400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527041.1">
        <property type="nucleotide sequence ID" value="XM_028670272.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPI8"/>
    <dbReference type="GeneID" id="39732454"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00392400"/>
    <dbReference type="OMA" id="HEGIICM"/>
    <dbReference type="OrthoDB" id="2019917at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026059">
        <property type="entry name" value="Rab3GAP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032839">
        <property type="entry name" value="RAB3GAP_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12472:SF0">
        <property type="entry name" value="RAB3 GTPASE-ACTIVATING PROTEIN NON-CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12472">
        <property type="entry name" value="RAB3-GAP REGULATORY DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14655">
        <property type="entry name" value="RAB3GAP2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101898">
        <property type="entry name" value="NHL repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab3-GAP regulatory subunit N-terminal" evidence="1">
        <location>
            <begin position="296"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="531" mass="63085" checksum="60D9DACA515A554A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPL8</accession>
    <name>A0A1J1GPL8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00183900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527268.1">
        <property type="nucleotide sequence ID" value="XM_028670524.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPL8"/>
    <dbReference type="GeneID" id="39730366"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00183900"/>
    <dbReference type="OMA" id="ETMSVCF"/>
    <dbReference type="OrthoDB" id="363195at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012317371" evidence="2">
        <location>
            <begin position="21"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="603" mass="69102" checksum="60E41B849FF9F7F3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPW6</accession>
    <name>A0A1J1GPW6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Early transcribed membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ETRAMP</name>
        <name evidence="3" type="ORF">PGAL8A_00001000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000031">
        <property type="protein sequence ID" value="CRG94549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527364.1">
        <property type="nucleotide sequence ID" value="XM_028670630.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPW6"/>
    <dbReference type="GeneID" id="39728532"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00001000"/>
    <dbReference type="OMA" id="YKCISPP"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006389">
        <property type="entry name" value="Early_transc_mb_plasmodium"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01495">
        <property type="entry name" value="ETRAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09716">
        <property type="entry name" value="ETRAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="400" mass="45547" checksum="7201EB25F01BC663" modified="2017-02-15" version="1">MRISKVFYFFNFLLVTHLLIPYLSKKNENLKGLNSLKDVEEELERREKKKKKIILYSTLASALALATVVAIGLGIYSHERKKGRDLKPLDKEFFEKEGDDEKPKKPYFPRWVSKESKSVKLEGDTSPKSYKKKYKHPPKEKPRTSKTVTEPKSRKYIKLAPTFTIPESIILPEPITSPEPTKFPEPPELPESLILPEPPKIPESLILPEPPKIPESLKLPEPPKIPESLILPEPPKIPKSLILPEPPKIPKSLILPEPPKIPKSLILPEPPKIPKSLILPEPPKIPKSLILPEPPKIPKSLILPEPPKIPKSLILPEPPKIPKSLILPEPPKIPKSLILPEPPKIPKSLILPEPPKIPKSLILPEPPKIPESIILPEPPKIPKSFFFFFFLHFNFFFFFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPX3</accession>
    <name>A0A1J1GPX3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">KELT protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00195200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527372.1">
        <property type="nucleotide sequence ID" value="XM_028670639.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPX3"/>
    <dbReference type="GeneID" id="39730479"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00195200"/>
    <dbReference type="OMA" id="NRCVRKV"/>
    <dbReference type="OrthoDB" id="376180at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="544" mass="64528" checksum="BD8DA4F6EC946EA2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPZ0</accession>
    <name>A0A1J1GPZ0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Peptidyl-prolyl cis-trans isomerase, putative</fullName>
            <ecNumber evidence="10">5.2.1.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">CYP81</name>
        <name evidence="10" type="ORF">PGAL8A_00079200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SYF2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="10"/>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525912.1">
        <property type="nucleotide sequence ID" value="XM_028670377.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPZ0"/>
    <dbReference type="GeneID" id="39729317"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00079200"/>
    <dbReference type="OrthoDB" id="408413at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013260">
        <property type="entry name" value="mRNA_splic_SYF2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13264">
        <property type="entry name" value="GCIP-INTERACTING PROTEIN P29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13264:SF5">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR SYF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08231">
        <property type="entry name" value="SYF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="9">
        <location>
            <begin position="8"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="217"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="411"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="296"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="221"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="413"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG93090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="651" mass="77689" checksum="067F5A70F444FBC0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPZ9</accession>
    <name>A0A1J1GPZ9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Vacuolar protein sorting-associated protein 45, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">VPS45</name>
        <name evidence="2" type="ORF">PGAL8A_00407000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the STXBP/unc-18/SEC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527187.1">
        <property type="nucleotide sequence ID" value="XM_028670435.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPZ9"/>
    <dbReference type="GeneID" id="39732600"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00407000"/>
    <dbReference type="OMA" id="VHQLNNA"/>
    <dbReference type="OrthoDB" id="10266265at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.830.10">
        <property type="entry name" value="Syntaxin Binding Protein 1, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043154">
        <property type="entry name" value="Sec-1-like_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043127">
        <property type="entry name" value="Sec-1-like_dom3a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001619">
        <property type="entry name" value="Sec1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027482">
        <property type="entry name" value="Sec1-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036045">
        <property type="entry name" value="Sec1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11679">
        <property type="entry name" value="VESICLE PROTEIN SORTING-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00995">
        <property type="entry name" value="Sec1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005715">
        <property type="entry name" value="VPS45_Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56815">
        <property type="entry name" value="Sec1/munc18-like (SM) proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="675" mass="80654" checksum="C8302475AC332B67" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ65</accession>
    <name>A0A1J1GQ65_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00183600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527265.1">
        <property type="nucleotide sequence ID" value="XM_028670520.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ65"/>
    <dbReference type="GeneID" id="39730363"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00183600"/>
    <dbReference type="OMA" id="YLLHMSF"/>
    <dbReference type="OrthoDB" id="371459at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="458" mass="55442" checksum="B8E8528E4ED2A57F" modified="2017-02-15" version="1">MEFPNKQWFDNKLYKLENFYRKNNSVHYYLKKNDIVTALAEIRKGTSPFMRDECNRTALDLAILLFMRKFHESIFTSFITDFIYKNISDKSRMEFVYNKKGEIINYDEKMFYCYDDIMEQLKKNKKSNRNKMKSYNDDNIISCLLLQKKIKYSPLLVKYQDDSKYTSELEYKKKDLLFLFEEVLTTPMSKNIQVQLDELLRKMNALLFFIKTLSKNITLKKYSESVIKEEISNLSFPFLYNTTIHTLFRLFPLNHYNEKWNIKNPADSRRLINKILSKNLIGNEIIKFIGKSLFYFSDLLKIYNPNVFKQDPIISQYLLHMSFTLDNEYLFNLIINKNNVFDKIDIFHWDELIDSISPYKKMFKPYYKPLIYARLKKEFLDILEKDFYEYKKKDIKNHKKNNTSKYIKDDLNSTFRILKIYEDIFNASDYNELEKVLKKKILKLEDKKRKKKGEKTKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ89</accession>
    <name>A0A1J1GQ89_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Thioredoxin peroxidase 1, putative</fullName>
            <ecNumber evidence="9">1.11.1.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">Trx-Px1</name>
        <name evidence="9" type="ORF">PGAL8A_00198100</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peroxiredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.15" evidence="9"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527399.1">
        <property type="nucleotide sequence ID" value="XM_028670670.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ89"/>
    <dbReference type="GeneID" id="39730508"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00198100"/>
    <dbReference type="OMA" id="VRHTTCN"/>
    <dbReference type="OrthoDB" id="185659at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033554">
        <property type="term" value="P:cellular response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03015">
        <property type="entry name" value="PRX_Typ2cys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000002">
        <property type="entry name" value="Alkyl hydroperoxide reductase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050217">
        <property type="entry name" value="Peroxiredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019479">
        <property type="entry name" value="Peroxiredoxin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10681">
        <property type="entry name" value="THIOREDOXIN PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10681:SF164">
        <property type="entry name" value="THIOREDOXIN PEROXIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10417">
        <property type="entry name" value="1-cysPrx_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 9" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="5 6" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="8">
        <location>
            <begin position="3"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity" evidence="7">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="195" mass="21819" checksum="32ECBEBC2B599CDC" modified="2017-02-15" version="1">MSMYVGKEAPFFKAEAVFGDNSFGEVSLTDFIGKKYVLLYFYPLDFTFVCPSEIIALDRALHKFKERDVELLGCSVDSKFSHLAWKKTSLSNGGIGNIKHTLLSDITKSISKDYNVLFDDSVSLRAFFLIDKKGIIQHALINNLAIGRSVDEILRIIDALQHHEKYGDVCPANWAKGKEAMKPSAEGVSDYLSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQG1</accession>
    <name>A0A1J1GQG1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00205300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527471.1">
        <property type="nucleotide sequence ID" value="XM_028670749.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQG1"/>
    <dbReference type="GeneID" id="39730580"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00205300"/>
    <dbReference type="OrthoDB" id="371976at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="408"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="716" mass="85439" checksum="2DF4D4150AC98E65" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQM0</accession>
    <name>A0A1J1GQM0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DEAD/DEAH box helicase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00198300</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527401.1">
        <property type="nucleotide sequence ID" value="XM_028670672.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730510"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00198300"/>
    <dbReference type="OMA" id="MCSATEF"/>
    <dbReference type="OrthoDB" id="5575at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001786">
        <property type="entry name" value="DEAD/DEAH box helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001787">
        <property type="entry name" value="Putative DEAD/DEAH box helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000024">
        <property type="entry name" value="U5 small nuclear ribonucleoprotein helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.10">
        <property type="entry name" value="Sec63 N-terminal domain-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050474">
        <property type="entry name" value="Hel308_SKI2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004179">
        <property type="entry name" value="Sec63-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057842">
        <property type="entry name" value="WH_MER3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961:SF4">
        <property type="entry name" value="ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47961">
        <property type="entry name" value="DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02889">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23445">
        <property type="entry name" value="WHD_SNRNP200"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039073">
        <property type="entry name" value="BRR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00973">
        <property type="entry name" value="Sec63"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158702">
        <property type="entry name" value="Sec63 N-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="323"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="649"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="1335"/>
            <end position="1511"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="1667"/>
            <end position="1840"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="383"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="66"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2319" mass="273813" checksum="BB35A80F4803FBAF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR17</accession>
    <name>A0A1J1GR17_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA/RNA-binding protein KIN17, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00226900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the KIN17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527687.1">
        <property type="nucleotide sequence ID" value="XM_028670990.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR17"/>
    <dbReference type="GeneID" id="39730796"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00226900"/>
    <dbReference type="OrthoDB" id="10266249at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.2030:FF:000001">
        <property type="entry name" value="DNA/RNA-binding protein KIN17, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2030">
        <property type="entry name" value="DNA/RNA-binding protein Kin17, conserved domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056767">
        <property type="entry name" value="C2H2-Znf_KIN17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019447">
        <property type="entry name" value="DNA/RNA-bd_Kin17_WH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037321">
        <property type="entry name" value="KIN17-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038254">
        <property type="entry name" value="KIN17_WH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041995">
        <property type="entry name" value="KOW_KIN17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12805:SF0">
        <property type="entry name" value="DNA_RNA-BINDING PROTEIN KIN17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12805">
        <property type="entry name" value="KIN17 KIN, ANTIGENIC DETERMINANT OF RECA PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25095">
        <property type="entry name" value="C2H2-zf_KIN17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25092">
        <property type="entry name" value="SH3_KIN17_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10357">
        <property type="entry name" value="WH_KIN17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01253">
        <property type="entry name" value="Kin17_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="233"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="279"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="233"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="426" mass="50368" checksum="80EE48CFE94C1199" modified="2017-02-15" version="1">MPRAEPGTPKWLANKMKAKGLQKLKWYCQMCEKQCRDENGFKCHRLSETHQRQMQIFCQDANKFMDEYSSMFEKEFMRLMKTRFCRTRILANTVYTNLISDKTHIHMNATVWVTLTDFVLYLGKTGKCKIEQTERGWYLEYIDREKIEREKSFQERKKIDYSYEQLKEKRINKAIEEAKKEGKFIESEYTGIKKKNDEKIVISSIKAKDNSQVTKPSINIFLNEALKKSEEKKKKADGLLNKQDNDKKELSKKRPLSSLDLLILENEEKKKLKGDTSDLSNYQNNIDKTKKLYEENEKKINRDYQNNEDEDNIWICKNIVVKVVDKKHKYYNKKGVIISLYSNDKKKCEIRMDNKEIFTAYQKQLQTVIPKIGKEVLILKGKYKGLKGKIKKILVDEEVVLVALDDKNSNEIITKHIPYDDVSKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR32</accession>
    <name>A0A1J1GR32_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein disulfide isomerase, putative</fullName>
            <ecNumber evidence="4">5.3.4.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">PDI-14</name>
        <name evidence="4" type="ORF">PGAL8A_00232100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein disulfide isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.4.1" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527738.1">
        <property type="nucleotide sequence ID" value="XM_028671046.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR32"/>
    <dbReference type="GeneID" id="39730848"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00232100"/>
    <dbReference type="OMA" id="LIVYTHW"/>
    <dbReference type="OrthoDB" id="72053at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034976">
        <property type="term" value="P:response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02995">
        <property type="entry name" value="PDI_a_PDI_a'_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000358">
        <property type="entry name" value="Protein disulfide-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18929">
        <property type="entry name" value="PROTEIN DISULFIDE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18929:SF219">
        <property type="entry name" value="THIOREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012046035" evidence="2">
        <location>
            <begin position="19"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="384"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="543" mass="65477" checksum="ABDC23C9508279C9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR33</accession>
    <name>A0A1J1GR33_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">SNARE protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00228500</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GOSR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527703.1">
        <property type="nucleotide sequence ID" value="XM_028671007.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR33"/>
    <dbReference type="GeneID" id="39730812"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00228500"/>
    <dbReference type="OMA" id="ITQQMKK"/>
    <dbReference type="OrthoDB" id="377411at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005801">
        <property type="term" value="C:cis-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005797">
        <property type="term" value="C:Golgi medial cisterna"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048219">
        <property type="term" value="P:inter-Golgi cisterna vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023601">
        <property type="entry name" value="Golgi_SNAP_su1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21094:SF2">
        <property type="entry name" value="GOLGI SNAP RECEPTOR COMPLEX MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21094">
        <property type="entry name" value="GOS-28 SNARE- RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12352">
        <property type="entry name" value="V-SNARE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="220"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="34"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG94888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="238" mass="29055" checksum="5FAE5480B36625C2" modified="2017-02-15" version="1">MKKNYSVLDDEEKLNDYDYNISYREYKKTIRNLQIKFEKDLSELKERINLYENNIQKKNENDIYEFISNNKKKIEELENCHKNGIENLFIMKSYFSKNSTYSIEIDRYLSIFDKFKIQLQSIKNTFDKIYLNCNIYIKKENNKFINNNEINHVFKERNALEYSLKELDNIISIGENTNFKLKNQNYHIMQHIKKINQLNSYLPQIQKILKKIKYYNLKRIIILSVTISLCIFFFFIFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR34</accession>
    <name>A0A1J1GR34_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00120500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526320.1">
        <property type="nucleotide sequence ID" value="XM_028674717.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR34"/>
    <dbReference type="GeneID" id="39729730"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00120500"/>
    <dbReference type="OMA" id="QNTRSEY"/>
    <dbReference type="OrthoDB" id="372968at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="655"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="669"/>
            <end position="679"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="931" mass="111744" checksum="8D19D088CA8CBD97" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR99</accession>
    <name>A0A1J1GR99_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Translation initiation factor eIF2B subunit gamma</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">eIF2B GDP-GTP exchange factor subunit gamma</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00238600</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">Component of the translation initiation factor 2B (eIF2B) complex which is a heterodecamer of two sets of five different subunits: alpha, beta, gamma, delta and epsilon. Subunits alpha, beta and delta comprise a regulatory subcomplex and subunits epsilon and gamma comprise a catalytic subcomplex. Within the complex, the hexameric regulatory complex resides at the center, with the two heterodimeric catalytic subcomplexes bound on opposite sides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eIF-2B gamma/epsilon subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527802.1">
        <property type="nucleotide sequence ID" value="XM_028671118.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR99"/>
    <dbReference type="GeneID" id="39730914"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00238600"/>
    <dbReference type="OMA" id="NCVINPK"/>
    <dbReference type="OrthoDB" id="285674at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005851">
        <property type="term" value="C:eukaryotic translation initiation factor 2B complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002183">
        <property type="term" value="P:cytoplasmic translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051960">
        <property type="entry name" value="eIF2B_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056764">
        <property type="entry name" value="LbH_EIF2B3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45989">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45989:SF1">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25084">
        <property type="entry name" value="LbH_EIF2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 11" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EIF2B subunit epsilon/gamma LbH" evidence="10">
        <location>
            <begin position="379"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="162"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00044196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF25084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG94989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="475" mass="55313" checksum="D3696B64E7D1A91B" modified="2017-02-15" version="1">MSNLNYSRVPAGTFIEFQVVILTNDENNFTNELCDNKCKALIKICNRCMIYYIIKNIIEQKLKYITIVVNGKYYNDMVNYINEAFPDNYKFDDKKSKNNYCIDIESYSTSDNEDIGSVQCLLQIKNKIKTDFIVVSCDILGFVDFHSLANLFRGENAMCGILLLEDDQIKSTEKKKKEIKDEYLNLENHVWVCIDKNSRVVSIKDSLSMKQNGKLKISKINLLLHKNFLLKTDLLDSHVYIFKHYILNILEHKEKKFTSIKYDLIPYLVKIQNTPVSSRYCKSEFKFNMYNTLIDKYEGTNDNEIKKVLPIADIIDNHENVESVVCYVQPKTTGFCQRINNIPNFFKANLLFCVTRHDQLKNVLPPYCFFLLTEKNQSYRDCIISSHFNHEENVLLKKSVLGKNIKIKKNTSIFRSILMDNITINENCVIQNSIICDNVVIENNCKLIDCIVKENSVIEKDGIFEKETLPLFISQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRA2</accession>
    <name>A0A1J1GRA2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00246200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527876.1">
        <property type="nucleotide sequence ID" value="XM_028671201.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRA2"/>
    <dbReference type="GeneID" id="39730990"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00246200"/>
    <dbReference type="OMA" id="NCGNVFH"/>
    <dbReference type="OrthoDB" id="365379at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16448">
        <property type="entry name" value="RING-H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="7"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="79"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="213"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="429" mass="50984" checksum="5280645C956D45AB" modified="2017-02-15" version="1">MYIIPECCICRLSLKNNLCIEKNCGNIFHYECMKKWIAFQKSCPLCKSTCYKKNLLSIHYEISEENKILIDDNIINKSKNELYEDLKKYESELIKIQNENEKYSLEILTLTNKNKILTETISKNNAKINEEKYEKLKLKELKDEYLKEKIILTTKIEEYDKELKKYKLIEKYLDDLNKEDLNKINLLFGFNVLSFDEQRNVILNYIKNSLNIQKKNESVIKELKENISEKDNEIISLKEKLYKYKLNNDIIDSNENNLSNDKNDSKSIKIKNKTIRRVATLESRNKNNRNNNLSFYSKSKTSDKTINNNFDFISFIDKKINSSNSPEKINLTPKKMKFHSIEVDLLRNKSIDKIFNNHIDKYDDKTEETFKKYSKEIEENHIDNSERTTKLIASSPSLKTFNNFKITKSRKRKSLNLQSTKITDFFRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRB3</accession>
    <name>A0A1J1GRB3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Asparagine synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00235900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527775.1">
        <property type="nucleotide sequence ID" value="XM_028671086.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRB3"/>
    <dbReference type="GeneID" id="39730887"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00235900"/>
    <dbReference type="OMA" id="KHPLCDE"/>
    <dbReference type="OrthoDB" id="10252281at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051857">
        <property type="entry name" value="Asn_synthetase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45937">
        <property type="entry name" value="ASPARAGINE SYNTHETASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45937:SF1">
        <property type="entry name" value="ASPARAGINE SYNTHETASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0061">Asparagine biosynthesis</keyword>
    <keyword evidence="3" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1121" mass="135393" checksum="625E81BD74FA00FB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRB8</accession>
    <name>A0A1J1GRB8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tryptophan--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Tryptophanyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00247800</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>tRNA(Trp) + L-tryptophan + ATP = L-tryptophyl-tRNA(Trp) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24080"/>
            <dbReference type="Rhea" id="RHEA-COMP:9671"/>
            <dbReference type="Rhea" id="RHEA-COMP:9705"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78535"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.2" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527892.1">
        <property type="nucleotide sequence ID" value="XM_028671218.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRB8"/>
    <dbReference type="GeneID" id="39731006"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00247800"/>
    <dbReference type="OrthoDB" id="10261385at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004830">
        <property type="term" value="F:tryptophan-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006436">
        <property type="term" value="P:tryptophanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00806">
        <property type="entry name" value="TrpRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.240.10:FF:000007">
        <property type="entry name" value="Tryptophan--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000138">
        <property type="entry name" value="Tryptophan--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.54.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.240.10">
        <property type="entry name" value="Tyrosyl-Transfer RNA Synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002306">
        <property type="entry name" value="Trp-tRNA-ligase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00233">
        <property type="entry name" value="trpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10055:SF1">
        <property type="entry name" value="TRYPTOPHAN--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10055">
        <property type="entry name" value="TRYPTOPHANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01039">
        <property type="entry name" value="TRNASYNTHTRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="ThrRS/AlaRS common domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG95079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="627" mass="72934" checksum="72CC2C69148C267E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRL9</accession>
    <name>A0A1J1GRL9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00255800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527966.1">
        <property type="nucleotide sequence ID" value="XM_028671300.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRL9"/>
    <dbReference type="GeneID" id="39731086"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00255800"/>
    <dbReference type="OMA" id="NIFHEYI"/>
    <dbReference type="OrthoDB" id="370501at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="9"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="999"/>
            <end position="1026"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1104" mass="132574" checksum="17372C1C3F422C18" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS29</accession>
    <name>A0A1J1GS29_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00007100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528116.1">
        <property type="nucleotide sequence ID" value="XM_028671467.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728593"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00007100"/>
    <dbReference type="OMA" id="HKYDKKY"/>
    <dbReference type="OrthoDB" id="386214at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36489:SF1">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36489">
        <property type="entry name" value="PROTEIN-COUPLED RECEPTOR GPR1, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="955"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1043"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1364"/>
            <end position="1444"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="429"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="955"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1055"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1075"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1394"/>
            <end position="1405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1413"/>
            <end position="1437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1566" mass="186330" checksum="8DE5C4F8CAC404F4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSA0</accession>
    <name>A0A1J1GSA0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Monocarboxylate transporter, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00014800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528190.1">
        <property type="nucleotide sequence ID" value="XM_028671549.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSA0"/>
    <dbReference type="GeneID" id="39728670"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00014800"/>
    <dbReference type="OMA" id="HQLWLMW"/>
    <dbReference type="OrthoDB" id="410267at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17353">
        <property type="entry name" value="MFS_OFA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052983">
        <property type="entry name" value="MFS_Riboflavin_Transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43385">
        <property type="entry name" value="RIBOFLAVIN TRANSPORTER RIBJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43385:SF1">
        <property type="entry name" value="RIBOFLAVIN TRANSPORTER RIBJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="283"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="318"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="348"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="374"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="408"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="436"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="457" mass="51607" checksum="BBEA1F7846EEFA17" modified="2017-02-15" version="1">MKKAESSNSSSKYKIILGGFLIHCTLGSIYCFSNISVYIISYMKIIGCSSVKYKDSSWIYVLTLIFQCFFGFFGGILNQNLGPQISVLLGGWLMCLGILLSYFTVFNFYLFLMTYGILCGIGCGIAYPIPLSVAVKKHYDYKGVISGIIFIGRGLSVFIICPLQNYFINKYNYMPDYIPEMEDSGEKYFSNLDILNKVPYLFIYEGIFFAIIQFIGACLISDSKEKSKEFMTFTDKNSKLLYFDEKSFSNKNNGISNSMKTLSNTSNFSYKETSNTFINRNFILIWLMIFFNWQAISYTQVFWKIFGLNYLYIDDRSLSILGAVSSLFNIFGRLFWGLISDLTNFKIALILMSLLMSFLTVTLTLSGLYGIITYSIWVCLIFFCHAGTFSIFPSITAHTFGTKNFGPIFGLLFTARAFSSIINAMISAVLLNNIGNIAMCAIVSISSFVSIMLAVVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSD1</accession>
    <name>A0A1J1GSD1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Derlin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00013600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the derlin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528178.1">
        <property type="nucleotide sequence ID" value="XM_028671536.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSD1"/>
    <dbReference type="GeneID" id="39728658"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00013600"/>
    <dbReference type="OMA" id="ASMYNEN"/>
    <dbReference type="OrthoDB" id="1716531at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007599">
        <property type="entry name" value="DER1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11009">
        <property type="entry name" value="DER1-LIKE PROTEIN, DERLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04511">
        <property type="entry name" value="DER1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009618926" description="Derlin" evidence="8">
        <location>
            <begin position="19"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG95367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="365" mass="44465" checksum="9E5E33784D46F77B" modified="2017-02-15" version="1">MFLCKFFLTSILISVIYAKIFMNNFTNSLLKNVHITSDKNEDILRTSYSKIKSRVKQYYAKEKNRILKKKKKKFSLNYSKCAEKYCFLNSLKFTEIKENVKVLFNLDYAENNIIFSYIKSFKRTPPITKFYLISTFLLSALIHINKNVYKLILFDFNKIFKKYEVWRLFSPYLYIGNLYLQYILMFNYLNIYMSAVEIAHYKKPEDFLIFLTFGYLSNIIFTIIGSMYNENIMNMKKNIHKIVNLIIKQKNNENIEIKKENYNHLGYVFSTYILYYWSRINEGSLINCFELFLIKAEYVPFFFIIQNMLLYNEFSFYEVASIFSSYIFFTYEKYIKLEFLKYIFLNFLKFIRVYNIYDKYKEEYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSF9</accession>
    <name>A0A1J1GSF9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00395200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527069.1">
        <property type="nucleotide sequence ID" value="XM_028670303.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732482"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00395200"/>
    <dbReference type="OMA" id="NINCGNI"/>
    <dbReference type="OrthoDB" id="372364at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1505" mass="181509" checksum="AD926CA3E780E425" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSN4</accession>
    <name>A0A1J1GSN4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tyrosine kinase-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">TKL1</name>
        <name evidence="4" type="ORF">PGAL8A_00402400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527141.1">
        <property type="nucleotide sequence ID" value="XM_028670383.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSN4"/>
    <dbReference type="GeneID" id="39732554"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00402400"/>
    <dbReference type="OMA" id="IHHEKVY"/>
    <dbReference type="OrthoDB" id="312720at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAM" evidence="3">
        <location>
            <begin position="730"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="822"/>
            <end position="1082"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="563"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="569"/>
            <end position="579"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1102" mass="130752" checksum="0B04A0E1BE6CF169" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSS1</accession>
    <name>A0A1J1GSS1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00277900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528390.1">
        <property type="nucleotide sequence ID" value="XM_028671771.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSS1"/>
    <dbReference type="GeneID" id="39731312"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00277900"/>
    <dbReference type="OrthoDB" id="15688at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12324">
        <property type="entry name" value="RRM_RBM8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008111">
        <property type="entry name" value="RNA-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033744">
        <property type="entry name" value="RRM_RBM8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45894">
        <property type="entry name" value="RNA-BINDING PROTEIN 8A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01738">
        <property type="entry name" value="RNABINDINGM8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="22"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="106" mass="12447" checksum="B92BB10C797349CA" modified="2017-02-15" version="1">MEDNLSNVFKKDEIPAKSIEGWIIIITNIHGEARDDYIREVFEKFGQIKNLHLNLDRRTGFLKGYAFLEYENFVDAKRAIDEMDGSILLNQEIHVDWAFVQEKSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSY0</accession>
    <name>A0A1J1GSY0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00280100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528412.1">
        <property type="nucleotide sequence ID" value="XM_028671795.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSY0"/>
    <dbReference type="GeneID" id="39731334"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00280100"/>
    <dbReference type="OMA" id="QRPHYRK"/>
    <dbReference type="OrthoDB" id="1703270at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11380">
        <property type="entry name" value="Ribosomal_S8e_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.290.70:FF:000001">
        <property type="entry name" value="40S ribosomal protein S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001047">
        <property type="entry name" value="Ribosomal_eS8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022309">
        <property type="entry name" value="Ribosomal_Se8/biogenesis_NSA2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00307">
        <property type="entry name" value="eS8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10394">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01201">
        <property type="entry name" value="Ribosomal_S8e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="125"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="128"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="218" mass="25140" checksum="7148BE47C6619A40" modified="2017-02-15" version="1">MGISRDGRHKLRLTGGKKKIHKKKRKYELGRPPSNTKLGSRQVHIVRGRGRNYKYRAIKLDSGSFSWPSFGISKMTRIIDVVYNASNNELVRTKTLVKNCIVLIDSHPFTAWYENTFGMTLGKKKKTKVEDENKEENKAEEEDKEEKKNNEKNKSYSVIKKIGKSKQIDPALLEQFKQGRVLACISSRPGQCGKADGYIIEGDELLFYKRKMDKKKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTF3</accession>
    <name>A0A1J1GTF3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Multidrug efflux pump, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00403500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527152.1">
        <property type="nucleotide sequence ID" value="XM_028670395.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTF3"/>
    <dbReference type="GeneID" id="39732565"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00403500"/>
    <dbReference type="OMA" id="FFMHPLG"/>
    <dbReference type="OrthoDB" id="2126698at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11206">
        <property type="entry name" value="MULTIDRUG RESISTANCE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="297"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="328"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="372"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="415"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="451"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="481"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="702"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="734"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="779"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="812"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="838"/>
            <end position="863"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="869" mass="102553" checksum="36E6D94F8AEE4B2B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTF6</accession>
    <name>A0A1J1GTF6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00298200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528578.1">
        <property type="nucleotide sequence ID" value="XM_028671980.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731515"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00298200"/>
    <dbReference type="OMA" id="NSFYCLH"/>
    <dbReference type="OrthoDB" id="372113at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="234"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1235"/>
            <end position="1260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1284"/>
            <end position="1316"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="740"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="243"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1238"/>
            <end position="1249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1284"/>
            <end position="1297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1304"/>
            <end position="1316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1579" mass="191102" checksum="08D6650D4C857DA9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTI1</accession>
    <name>A0A1J1GTI1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">KS1 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00200300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527421.1">
        <property type="nucleotide sequence ID" value="XM_028670694.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTI1"/>
    <dbReference type="GeneID" id="39730529"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00200300"/>
    <dbReference type="OMA" id="ELECEKD"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="249" mass="28997" checksum="1B3603D0399EC884" modified="2017-02-15" version="1">MVDSPKKKRTLNTSEDKKDKKNMGSKKNNPVESSENMEENIENVIGDKKNDNMKKERKKKKERKNKENDIDKINDDNEEQEEGNEEDTLKKFSVDTSENEDEKDDDDNDNDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDDFEDIDDDDDDDDDDDDEDDDEDDEDDDDDDEEEDDDKNDYIKEDTKNNDGEGDNAEVKKESDEEGFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTQ0</accession>
    <name>A0A1J1GTQ0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Btz domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PGAL8A_00287000</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CASC3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528481.1">
        <property type="nucleotide sequence ID" value="XM_028671872.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTQ0"/>
    <dbReference type="GeneID" id="39731403"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00287000"/>
    <dbReference type="OMA" id="YSNGMYS"/>
    <dbReference type="OrthoDB" id="373011at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035145">
        <property type="term" value="C:exon-exon junction complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018545">
        <property type="entry name" value="Btz_dom"/>
    </dbReference>
    <dbReference type="SMART" id="SM01044">
        <property type="entry name" value="Btz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="11" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="10" id="KW-0866">Nonsense-mediated mRNA decay</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="8" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Btz" evidence="14">
        <location>
            <begin position="50"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="30"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="260"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="562"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="659"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="33"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="50"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="260"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="575"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="595"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="676"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="700"/>
            <end position="710"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG95673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1026" mass="124313" checksum="C5117BC954DBC02A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTV2</accession>
    <name>A0A1J1GTV2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00317100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_028672188.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTV2"/>
    <dbReference type="GeneID" id="39731704"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00317100"/>
    <dbReference type="OMA" id="TWEILDY"/>
    <dbReference type="OrthoDB" id="433917at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="120" mass="14406" checksum="1AB233C7A2D0DA2F" modified="2017-02-15" version="1">MRYRLFPPLTFLSFLRKLHVYYSPARNEKTDVARRLIIFASSQKIKQRYPLLTVTWELLAYENPPMIEVEYLNGEKEKINIEYFSDRQKKEIINKWKYTASLDPFPEVLAPTIEKANKDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTV6</accession>
    <name>A0A1J1GTV6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-f protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00187300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000025">
        <property type="protein sequence ID" value="CRG94478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527296.1">
        <property type="nucleotide sequence ID" value="XM_028670556.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTV6"/>
    <dbReference type="GeneID" id="39730400"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00187300"/>
    <dbReference type="OMA" id="HETITLK"/>
    <dbReference type="OrthoDB" id="384111at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="595" mass="71555" checksum="279A04A0522F6043" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTW9</accession>
    <name>A0A1J1GTW9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Origin recognition complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ORC1</name>
        <name evidence="14" type="ORF">PGAL8A_00318700</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">ORC is composed of six subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the ORC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528782.1">
        <property type="nucleotide sequence ID" value="XM_028672207.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTW9"/>
    <dbReference type="GeneID" id="39731720"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00318700"/>
    <dbReference type="OMA" id="THYLKER"/>
    <dbReference type="OrthoDB" id="1926878at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005664">
        <property type="term" value="C:nuclear origin of replication recognition complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001186">
        <property type="entry name" value="Origin recognition complex subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054425">
        <property type="entry name" value="Cdc6_ORC1-like_ATPase_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050311">
        <property type="entry name" value="ORC1/CDC6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763:SF23">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22606">
        <property type="entry name" value="Cdc6-ORC-like_ATPase_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="13">
        <location>
            <begin position="611"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="91"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="226"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="493"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="92"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="226"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU365058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG95974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="992" mass="115590" checksum="8BE7C842E3A4440B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUN6</accession>
    <name>A0A1J1GUN6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Heat shock factor-binding protein 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">HSBP</name>
        <name evidence="4" type="ORF">PGAL8A_00347500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HSBP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529062.1">
        <property type="nucleotide sequence ID" value="XM_028672517.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUN6"/>
    <dbReference type="GeneID" id="39732005"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00347500"/>
    <dbReference type="OMA" id="QNSVNIC"/>
    <dbReference type="OrthoDB" id="4159489at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009643">
        <property type="entry name" value="HS1-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06825">
        <property type="entry name" value="HSBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="65"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="112" mass="13028" checksum="B85577BD70D42EC6" modified="2017-02-15" version="1">MLNNRSENFNFNESKNNNENNTSENLNNFCKSFNSSIPLEKNKKNTIPLNINDTFNSESKGDNLEIYVENMLNELKNKMQNLSNNLLSKVDNMEKSLEDLENIMIDFTNKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUQ3</accession>
    <name>A0A1J1GUQ3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00349100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529078.1">
        <property type="nucleotide sequence ID" value="XM_028672536.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732021"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00349100"/>
    <dbReference type="OMA" id="KHESTHQ"/>
    <dbReference type="OrthoDB" id="377384at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="2">
        <location>
            <begin position="1011"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1311"/>
            <end position="1339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1324"/>
            <end position="1339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1810" mass="212738" checksum="D8546D61471DF3A1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV12</accession>
    <name>A0A1J1GV12_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Zinc finger protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00227800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527696.1">
        <property type="nucleotide sequence ID" value="XM_028671000.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV12"/>
    <dbReference type="GeneID" id="39730805"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00227800"/>
    <dbReference type="OMA" id="IRYITIM"/>
    <dbReference type="OrthoDB" id="20534at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045234">
        <property type="entry name" value="Unkempt-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14493:SF50">
        <property type="entry name" value="RING FINGER PROTEIN UNKEMPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14493">
        <property type="entry name" value="UNKEMPT FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="5">
        <location>
            <begin position="14"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="5">
        <location>
            <begin position="58"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="5">
        <location>
            <begin position="100"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="14"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="58"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="100"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG94881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="653" mass="75539" checksum="D6314EA0B62E5C72" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVB0</accession>
    <name>A0A1J1GVB0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00344600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529033.1">
        <property type="nucleotide sequence ID" value="XM_028672485.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVB0"/>
    <dbReference type="GeneID" id="39731976"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00344600"/>
    <dbReference type="OMA" id="WFTEEQE"/>
    <dbReference type="OrthoDB" id="391347at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="199" mass="23531" checksum="662256E791546F17" modified="2017-02-15" version="1">MENFKVPSTYVYPNDMCELIRTLTNIIENKTKVDIDKKKIWDIINNIYDQWIKVAEREKEKDEKDYYKLISFLTLVLSTNWFNEEQEEIEYIVNEIYYSNMGITQSFSEEEVTKAIENSLGAEIKKCIINKNDLIIEFIKGDYGEGIFDGKIVLNINDGLFLHTEKEILQYTGKLPIDSYEIELAINSCDWKKYEEKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVH9</accession>
    <name>A0A1J1GVH9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fam-i protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00412700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000063">
        <property type="protein sequence ID" value="CRG96545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529350.1">
        <property type="nucleotide sequence ID" value="XM_028672837.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVH9"/>
    <dbReference type="GeneID" id="39732657"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00412700"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="121"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="235" mass="28029" checksum="516E602BBF555E87" modified="2017-02-15" version="1">MNLNLSDIIYIDSCETLDEEDSTASFAHREIKDATVSIPENPLHDDLNSRDSIQNPSEDINLDSVTSKNLLHKMSLSIFQLVIIFIFFLRFKKTYSLKLKAKNEMNMRLQKILNNSNKKVKDDLAKEMLEVKKKMEDGQKKLLKKKKEIEVQEKRVLKKKEEWEKKTLKEKQLCGEGMLKQLEEWEKRIINKGEVWKKRIKNEKIKLDKKMRKNKEEGEKKMLEIIEKFEKEMRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVI1</accession>
    <name>A0A1J1GVI1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L41</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00371800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">Component of the large ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the eukaryotic ribosomal protein eS32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529298.1">
        <property type="nucleotide sequence ID" value="XM_028672780.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVI1"/>
    <dbReference type="SMR" id="A0A1J1GVI1"/>
    <dbReference type="GeneID" id="39732248"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00371800"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007836">
        <property type="entry name" value="Ribosomal_eS32"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05162">
        <property type="entry name" value="Ribosomal_L41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00043969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU368055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="39" mass="5086" checksum="443B24066F98E651" modified="2017-02-15" version="1">MAHGASRYKKSRAKMRWKWKKKRTRRLQKKRRKMRQRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVI7</accession>
    <name>A0A1J1GVI7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00413600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000066">
        <property type="protein sequence ID" value="CRG96554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529358.1">
        <property type="nucleotide sequence ID" value="XM_028672846.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVI7"/>
    <dbReference type="GeneID" id="39732666"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00413600"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="185" mass="21597" checksum="1D664AA48EB60B12" modified="2017-02-15" version="1">MKTLTLYLKITTFLLLIWMYQCFYNCNSYKTLIDKNILEAKNELKYERLLAEGDIADKKQTKAEGGLEECALESEKNKSNNSAQYKNPCDPRHGVNTPSLWENFDKKAKEMDPKLRDQELNIELSKISHDNVNPFSKIYQRNIPDEGREILILSNTQGHSELKKLLDVFKKEMRDNKTESESKNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVQ4</accession>
    <name>A0A1J1GVQ4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Regulator of chromosome condensation, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00362800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529209.1">
        <property type="nucleotide sequence ID" value="XM_028672681.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVQ4"/>
    <dbReference type="GeneID" id="39732158"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00362800"/>
    <dbReference type="OMA" id="YSACLTK"/>
    <dbReference type="OrthoDB" id="10256179at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051625">
        <property type="entry name" value="Signaling_Regulatory_Domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22872">
        <property type="entry name" value="BTK-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22872:SF2">
        <property type="entry name" value="INHIBITOR OF BRUTON TYROSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00415">
        <property type="entry name" value="RCC1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13540">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="54"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="106"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="350"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="402"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="212"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="659"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="229"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="299"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1025" mass="120817" checksum="A252A6EE48E5DDE0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVQ6</accession>
    <name>A0A1J1GVQ6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00412300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000063">
        <property type="protein sequence ID" value="CRG96541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529346.1">
        <property type="nucleotide sequence ID" value="XM_028672833.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVQ6"/>
    <dbReference type="GeneID" id="39732653"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00412300"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="146" mass="17381" checksum="2ECEE5C0855460EE" modified="2017-02-15" version="1">MSTIQDDNLNEQSTKTTKRKNQKVGARKNVKENYKEVNIKEGNSQFCHRNFKLISLSLGYIINTFFYFLFIHIFSKILDKFIYMLSKISEYDYNDSLVIGSIKIIIILSLWYKYFSGGYDGDPFFQFFKHHFKLINKSKKTKNKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVT1</accession>
    <name>A0A1J1GVT1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA polymerase Rpb7-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00016300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPA43 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528205.1">
        <property type="nucleotide sequence ID" value="XM_028671565.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVT1"/>
    <dbReference type="GeneID" id="39728685"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00016300"/>
    <dbReference type="OMA" id="AQNPWYV"/>
    <dbReference type="OrthoDB" id="368781at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006362">
        <property type="term" value="P:transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.120">
        <property type="entry name" value="RNA polymerase Rpb7-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036898">
        <property type="entry name" value="RNA_pol_Rpb7-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045113">
        <property type="entry name" value="Rpb7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005576">
        <property type="entry name" value="Rpb7-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709:SF5">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II, III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03876">
        <property type="entry name" value="SHS2_Rpb7-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RNA polymerase Rpb7-like N-terminal" evidence="6">
        <location>
            <begin position="69"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="222" mass="25927" checksum="D42F16F2565F4CA2" modified="2017-02-15" version="1">MAQNPWYIKKSKVLRISKLENFINKFNEDYDHLICNPKFKYIKNTLNVILENPGLIINKKTFNIVRISCVAQLQPKYLDNVKDGLSIYLSNFMLKVNNDVEGFCICFNNIKLKEKEPKIINSDPSNMFLKISFKLLILVLKENYIIKAKINKIEPTKIHLDIFGIIEATLIEEIFKDFCYDSNNNTFIKDDKVYSLNDIINFTIKKVTYSDNGTNVKLIGYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVU1</accession>
    <name>A0A1J1GVU1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00413700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000067">
        <property type="protein sequence ID" value="CRG96555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529359.1">
        <property type="nucleotide sequence ID" value="XM_028672847.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVU1"/>
    <dbReference type="GeneID" id="39732667"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00413700"/>
    <dbReference type="OrthoDB" id="6362699at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="353"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="385" mass="45503" checksum="E20E167A83E7EAE5" modified="2017-02-15" version="1">MAFLNNDGCEDSEGDFTKCFMNICEINRNKFEASYCRIHPPIVDIKKTSNNNLNDLSKNLFTHEFIPSNFKSRIIILSNNDKDGILLLYEYNPHQHQYPDKTYLCRLRSINQKLTLCEAVNIEYLGRTLTFNSYDIINKENKNINMISLKNPNHKIIKSKYDKFLFKEHYCHHMKTNYISHCNKRYTVCKKINNDELHCSDANYSGNLIRLDYNKNSFLKRDYIYIPSGCLKENLDPVCTPHICVSHAFNEFFQCEYEEISVIKNIRPINNIIPTKNIMPKNDMRPINEIIPCNDLMQCKYMRSYKHILQPNSLKLMEDIRPIKNIGPNSKNPRAISLKHKDISDKNSFDNTALLAMSFMSFLVIFIFFFCLLYRTFRKKRRKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVZ5</accession>
    <name>A0A1J1GVZ5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00267000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000036">
        <property type="protein sequence ID" value="CRG95467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528277.1">
        <property type="nucleotide sequence ID" value="XM_028671646.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVZ5"/>
    <dbReference type="GeneID" id="39731199"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00267000"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="333" mass="40101" checksum="FF1E149D092903D8" modified="2017-02-15" version="1">MKTLTLYLKITTFLILIWIYQCFYNYDSYKTLIDKNRLQIKYELKYERVLTEGDIAGEKQTKVDGCQEECPVEKKKKEKKRKNWFITLVCHNTYDQWQRDTNEALFERFKNVTSEMDPKWRDQKWNNEWNEISANKFKEVSSIFHRSDVSKEEKKKLILDVKNELYILFVKFSEECKKEMRKNETKSESKKEMIDNKTDSESKKEIIDNKTDSESMKEMIDNKTDSESKKEMIENKTDSESKKEMIDNKTDSESMKDMIDNKTESESKNVIRDNISEPESMKEMRENRTESESKNEMRGNKRESESTKEQGKNKIKNEKSNIWKFLFNRFDNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW86</accession>
    <name>A0A1J1GW86_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Mitochondrial ATP synthase delta subunit, putative</fullName>
            <ecNumber evidence="11">3.6.3.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00375100</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase epsilon chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.14" evidence="11"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529331.1">
        <property type="nucleotide sequence ID" value="XM_028672816.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW86"/>
    <dbReference type="GeneID" id="39732281"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00375100"/>
    <dbReference type="OMA" id="KVLQQMC"/>
    <dbReference type="OrthoDB" id="270171at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12152">
        <property type="entry name" value="F1-ATPase_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.15.10">
        <property type="entry name" value="F0F1 ATP synthase delta/epsilon subunit, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001469">
        <property type="entry name" value="ATP_synth_F1_dsu/esu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020546">
        <property type="entry name" value="ATP_synth_F1_dsu/esu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036771">
        <property type="entry name" value="ATPsynth_dsu/esu_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13822">
        <property type="entry name" value="ATP SYNTHASE DELTA/EPSILON CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13822:SF7">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT DELTA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02823">
        <property type="entry name" value="ATP-synt_DE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51344">
        <property type="entry name" value="Epsilon subunit of F1F0-ATP synthase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP synthase F1 complex delta/epsilon subunit N-terminal" evidence="10">
        <location>
            <begin position="21"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG96526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="154" mass="17620" checksum="DD0C4944730A46D7" modified="2017-02-15" version="1">MLNKTRRIFFSTAKNSNLYLSLSSSSESIFRSQIIKRASFPGIEGYFTITNNHSPLVTLLRNGIITVEFDEKEKKQFFISDGIFIYKKSNDNNNNNNAEVVGVEIVPLEYLDKNKTIKVLQQLCAINDTTDDKWRKIKTMLGKELCSSILRITS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW94</accession>
    <name>A0A1J1GW94_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sugar transporter, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00432300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529546.1">
        <property type="nucleotide sequence ID" value="XM_028673055.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW94"/>
    <dbReference type="GeneID" id="39732855"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00432300"/>
    <dbReference type="OMA" id="GHMIWTH"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015149">
        <property type="term" value="F:hexose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045263">
        <property type="entry name" value="GLUT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503:SF8">
        <property type="entry name" value="FACILITATED GLUCOSE TRANSPORTER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="275"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="335"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="362"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="400"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="429"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="7">
        <location>
            <begin position="1"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="466" mass="54183" checksum="69FF996DCDC469EC" modified="2017-02-15" version="1">MLYLTKVISNACLAVINCGLCLSSTNLARKMIVDDFKLCPVGYRGCDKEKWYFSMFYFILYMSSFFGCFTSLFFKNTDRRKFIIIIHYLFIIGSLLTIYNTPHIIIFLFSQAFFGLAIGCSVVIVCFYVLEYSPKIYQNFYGFYIQTFFSIGILISYIFGACYENIKFQNPRTTDLVIKILYKVHLCLPMIFSLISLILLHFVFKLDTPLHLYVTKNYEKFEKLKTKINVKEFDEKKEYHMNPATNDVTLLYKDLPLIDFLKNKNLRKASFTGSFLCYLYSFNGCFLFFTKIFLFYRLFSSTMLNTFISVGFILLYVISTIISTFLAEHVQKKKLLIIGLVVQGLASAGLVITYFLSLENFLNQIIVTLSYATYFIGLSLGFGHMIWTHVFEMFPKECKVVGALCSYYPLFIGAFIISFIFEFASKQDYAYLFIIFLVSIIVSIICFNSFYKEDKELIAKKSSNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW97</accession>
    <name>A0A1J1GW97_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin-conjugating enzyme E2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00005000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528096.1">
        <property type="nucleotide sequence ID" value="XM_028671445.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW97"/>
    <dbReference type="GeneID" id="39728572"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00005000"/>
    <dbReference type="OMA" id="GPESCSY"/>
    <dbReference type="OrthoDB" id="6508832at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23807">
        <property type="entry name" value="UEV_UBE2V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000026">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="2">
        <location>
            <begin position="7"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="142" mass="16250" checksum="8E260CEBE2A38BF9" modified="2017-02-15" version="1">MSEVIVPRSFRLLDELERGQKGNVSEGVSFGLENADDITLSNWSCTIFGQPGTVFENRIYSLTIFCDDNYPDAPPTVKFDTKIEMTCVDNNGRVIKNNLPILKNWNRNYTIETILISLRQEMLSSANKRLPQPNEGEMYPHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWM1</accession>
    <name>A0A1J1GWM1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein MAM3, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00445200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529674.1">
        <property type="nucleotide sequence ID" value="XM_028673196.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWM1"/>
    <dbReference type="GeneID" id="39732985"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00445200"/>
    <dbReference type="OMA" id="HIMTDID"/>
    <dbReference type="OrthoDB" id="5353557at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010960">
        <property type="term" value="P:magnesium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045095">
        <property type="entry name" value="ACDP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12064">
        <property type="entry name" value="METAL TRANSPORTER CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12064:SF94">
        <property type="entry name" value="UNEXTENDED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="5">
        <location>
            <begin position="1"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="660"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="321"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="912" mass="107618" checksum="F08C48E74BCAD6F0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWT7</accession>
    <name>A0A1J1GWT7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cyclin-dependent kinases regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00436400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CKS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529585.1">
        <property type="nucleotide sequence ID" value="XM_028673098.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWT7"/>
    <dbReference type="GeneID" id="39732896"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00436400"/>
    <dbReference type="OMA" id="KMSINMH"/>
    <dbReference type="OrthoDB" id="440676at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.170.10">
        <property type="entry name" value="Cyclin-dependent kinase, regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000789">
        <property type="entry name" value="Cyclin-dep_kinase_reg-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036858">
        <property type="entry name" value="Cyclin-dep_kinase_reg-sub_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01111">
        <property type="entry name" value="CKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01084">
        <property type="entry name" value="CKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55637">
        <property type="entry name" value="Cell cycle regulatory proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU311113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="157" mass="18509" checksum="333054447DFC23C2" modified="2017-02-15" version="1">MNKSNRASLNQSNYNNNNDNYYSILEELAKSETPKFRSVKDSMDENLNLEFIRSSSENYTYKITSRGPVCYSAIYRDDKYVYRHIILSDGVRQYAENKVRKTNSFLTEHCIVNELQIDIGKGWKHFMIYDGKIRELILRKVLTSEDKLKMSINMHSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWW7</accession>
    <name>A0A1J1GWW7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">SAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00451200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529735.1">
        <property type="nucleotide sequence ID" value="XM_028673264.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWW7"/>
    <dbReference type="GeneID" id="39733045"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00451200"/>
    <dbReference type="OMA" id="NMLNGDN"/>
    <dbReference type="OrthoDB" id="364843at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013176090" description="SAP domain-containing protein" evidence="3">
        <location>
            <begin position="19"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="360"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="268"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="360"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="417"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="934" mass="111658" checksum="F9F9D739E89099E8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWZ2</accession>
    <name>A0A1J1GWZ2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Microtubule associated katanin, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00464500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat SWD2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529868.1">
        <property type="nucleotide sequence ID" value="XM_028673413.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWZ2"/>
    <dbReference type="GeneID" id="39733178"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00464500"/>
    <dbReference type="OMA" id="HNEGYIR"/>
    <dbReference type="OrthoDB" id="27537at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048188">
        <property type="term" value="C:Set1C/COMPASS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016070">
        <property type="term" value="P:RNA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037867">
        <property type="entry name" value="Swd2/WDR82"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19861:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 82"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19861">
        <property type="entry name" value="WD40 REPEAT PROTEIN SWD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0853">WD repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="383" mass="44308" checksum="D953E2DF36F4EDE8" modified="2017-02-15" version="1">MLILLKVIDNMLNTILYKKIKLTDDVVKKFEVIRAFKYKQSLTKNLAWSYYGELLLTSNENDSLTIYSLSKGNSLKTLHSKNCGVDVIRFLNNSNDVIVCSTRSSNLEHKQFLRFWDIKENKYLKSLPQIGNICELNGICVNQNKKLMLVNSDDGHVKLYYINCDTPLVLYKSDFMRPVSCFDNEGVIFAASFGKQEIHFYDLLMYDSGEYNIFNLKSNMDKNEFITNLLFTPNNKFIIISTNENKHFKIDSITGQYICSYNYPTYQENDNYFDINNNLSNEKNNISNSTINFCNQSNHIKNNNLNYNFEYSENDFFLPTITPDGQYIMCGWKDSGIHVWNENGNYITSLYGHEGPPKNVNFNPKCSILASSCLNVALWQPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX55</accession>
    <name>A0A1J1GX55_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00472800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529950.1">
        <property type="nucleotide sequence ID" value="XM_028673504.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX55"/>
    <dbReference type="GeneID" id="39733261"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00472800"/>
    <dbReference type="OMA" id="QRYDYES"/>
    <dbReference type="OrthoDB" id="372836at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="458"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="633" mass="74357" checksum="B9614BEA6D2A2E53" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXB0</accession>
    <name>A0A1J1GXB0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00285300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528464.1">
        <property type="nucleotide sequence ID" value="XM_028671852.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXB0"/>
    <dbReference type="GeneID" id="39731386"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00285300"/>
    <dbReference type="OMA" id="HNDEYHN"/>
    <dbReference type="OrthoDB" id="384271at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="321"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="695"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="338"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1143" mass="135784" checksum="6B6AF92EF71FF8FD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXB3</accession>
    <name>A0A1J1GXB3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pre-mRNA-splicing factor, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00467300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CWC26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529895.1">
        <property type="nucleotide sequence ID" value="XM_028673443.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXB3"/>
    <dbReference type="GeneID" id="39733206"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00467300"/>
    <dbReference type="OMA" id="CRYQTPY"/>
    <dbReference type="OrthoDB" id="6022at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070274">
        <property type="term" value="C:RES complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018609">
        <property type="entry name" value="Bud13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051112">
        <property type="entry name" value="CWC26_splicing_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31809">
        <property type="entry name" value="BUD13 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31809:SF0">
        <property type="entry name" value="BUD13 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09736">
        <property type="entry name" value="Bud13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="123"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="123"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="155"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="241"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="480" mass="57250" checksum="ECE926F7EEF1B777" modified="2017-02-15" version="1">MNEYLIKKYLKTSKKKNRRGKKSNIQIYDSEEETNKNIFRNNINKDDDEKFEFTESDRSSEIPITVTENNTMEILQLSNENKKKILESLSNNLVIGSCEAKNEINKEKGYYLKNISKKKEKKNENNTLKDYDSYNKNKESNNNNTNKNLNRHFKDKSMRYVESKEDSNLLSLRKKKDISESDSDLSVPRKKKYRNESDSDLSLPRKKKDRSESESDLSIPRRKKDRSESESDLSLPRKKKDRSESDSDLSYRRNTKYIKNEEDTLVNIKNEKNHEKKSESEYADSYISLALSSEMKNKELQFSDSKNFENEGVNSTIYRDKDGKIITREKWINEQRSEMKDKFEKNKKMREKKKRDNNNIKLEWGSGLVQKEIRKKNIEENEKLINKGNIINYDYDSDYELELKKKKRKEDPMNIYLDNKKENQKPTCRYQTPYNRFNILAGYRWDGVIRGNGFEQRRLEALELKRQQNKLTYMNNTSDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXD7</accession>
    <name>A0A1J1GXD7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00481400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530038.1">
        <property type="nucleotide sequence ID" value="XM_028673602.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXD7"/>
    <dbReference type="GeneID" id="39733347"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00481400"/>
    <dbReference type="OMA" id="SYAMITI"/>
    <dbReference type="OrthoDB" id="370797at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585:SF0">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="22"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="65"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="193"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="231"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="258"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="422"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="456"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="486"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="621" mass="73888" checksum="DD3A7F4A7B315523" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXI1</accession>
    <name>A0A1J1GXI1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00474300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000088">
        <property type="protein sequence ID" value="CRG97164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529967.1">
        <property type="nucleotide sequence ID" value="XM_028673523.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXI1"/>
    <dbReference type="GeneID" id="39733276"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00474300"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="98" mass="11674" checksum="6810B709D6E7E9AD" modified="2017-02-15" version="1">MSYNQSITTATPAVPLNTTLEDKIHNITNINYKPIKTYKLLFFIFVVIYLIVKLFSCRLFRCVQAHHRRRRNDNFDLISVDSGYFENFHEDEQEENVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXN2</accession>
    <name>A0A1J1GXN2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">25 kDa ookinete surface antigen, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00490300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530126.1">
        <property type="nucleotide sequence ID" value="XM_028673700.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXN2"/>
    <dbReference type="GeneID" id="39733436"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00490300"/>
    <dbReference type="OrthoDB" id="10060424at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.90.20.10">
        <property type="entry name" value="Plasmodium vivax P25 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010423">
        <property type="entry name" value="Pvs25/Psv28_EGF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06247">
        <property type="entry name" value="Plasmod_Pvs28"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013357531" evidence="2">
        <location>
            <begin position="22"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="3">
        <location>
            <begin position="25"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="3">
        <location>
            <begin position="62"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="3">
        <location>
            <begin position="107"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="3">
        <location>
            <begin position="154"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="215" mass="24497" checksum="936C2AB0876D4E7F" modified="2017-02-15" version="1">MNMSYLFFFFFIQLVLKYINSKVTENTICKDGFLIQMSNHFECNCNPGFVLTSESTCENKVECNANSLDKPCGDFSKCAYKDLQQKELTCKCIDGYDLEESICVPNECKNFRCESGKCVLDPKQEAKIPMCSCFIGIVPSKENNNTCTIEGQTECTLKCTKENETCKKTSGIYKCDCKDGYTFDKEENACISFSLFNILNLSIIFIISLIYFYII</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXX4</accession>
    <name>A0A1J1GXX4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00499000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530219.1">
        <property type="nucleotide sequence ID" value="XM_028673803.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXX4"/>
    <dbReference type="GeneID" id="39733523"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00499000"/>
    <dbReference type="OMA" id="LTAPYWF"/>
    <dbReference type="OrthoDB" id="1267328at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="116" mass="14009" checksum="D124A33D31CA5771" modified="2017-02-15" version="1">MPFIKKISQYFINGCYSCKNFSFRKFFNEDYFWTKANVGPFFIGLLTAPYWFSALKNIYWTLRYEKLNKQEILSDRFSWLYERMLEDEIHKTLLQKLPSYNFKNSGPENILGPSEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXX9</accession>
    <name>A0A1J1GXX9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00376100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000086">
        <property type="protein sequence ID" value="CRG97158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529961.1">
        <property type="nucleotide sequence ID" value="XM_028673516.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXX9"/>
    <dbReference type="GeneID" id="39732291"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00376100"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="292"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="326" mass="37849" checksum="0C6A7F95D0FDDAF9" modified="2017-02-15" version="1">MALLYNEGCEILKGEVTKCSMRICPLNSHKLTSLFCSYEILPVKAEKDSNNKLNDLSKNIFKYQRYKPHNHSRIIFLSNNDVDGIVFLFEYNAFSYKYPTKTYLCRFRKISQKATICEHIDASYLGKTLSFNSYDVINGKDNIINIKRSKNSKHTVTELKYRDLSFSRSACHILKGKYIENKPCMFYLCEVVNGHLSCFNANYSGRLIFINDIIDSAIEKQKFLYLPGSCLTKDSNFICDPQLCQYNSTQKLTSCEKLEISSIKNVFPSRGILEPAPTYMPISHENRPSSSILLATSLLPFLVMLVFIWCFVYKFLRRRKRKGYRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXY0</accession>
    <name>A0A1J1GXY0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PI3K/PI4K catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00499800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530227.1">
        <property type="nucleotide sequence ID" value="XM_028673812.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733531"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00499800"/>
    <dbReference type="OMA" id="HNYQNKH"/>
    <dbReference type="OrthoDB" id="5570127at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14025">
        <property type="entry name" value="FANCONI ANEMIA GROUP M FANCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14025:SF20">
        <property type="entry name" value="FANCONI ANEMIA GROUP M PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="520"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="565"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="4208"/>
            <end position="4230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="4459"/>
            <end position="4476"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="8">
        <location>
            <begin position="7749"/>
            <end position="8177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="877"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1944"/>
            <end position="1967"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="2705"/>
            <end position="2760"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="3572"/>
            <end position="3597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="4612"/>
            <end position="4669"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="7097"/>
            <end position="7162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="8405"/>
            <end position="8434"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="6660"/>
            <end position="6687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="7103"/>
            <end position="7112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="7127"/>
            <end position="7137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="7153"/>
            <end position="7162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG97426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="8470" mass="1022408" checksum="1F61400C380875AD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXZ3</accession>
    <name>A0A1J1GXZ3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Myb2 transcription factor, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">Myb2</name>
        <name evidence="16" type="ORF">PGAL8A_00493100</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CEF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530154.1">
        <property type="nucleotide sequence ID" value="XM_028673730.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXZ3"/>
    <dbReference type="SMR" id="A0A1J1GXZ3"/>
    <dbReference type="GeneID" id="39733464"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00493100"/>
    <dbReference type="OMA" id="QCLDHYE"/>
    <dbReference type="OrthoDB" id="1410009at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11659">
        <property type="entry name" value="SANT_CDC5_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000021">
        <property type="entry name" value="CDC5 cell division cycle 5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000091">
        <property type="entry name" value="CDC5 cell division cycle 5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047242">
        <property type="entry name" value="CDC5L/Cef1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021786">
        <property type="entry name" value="Cdc5p/Cef1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047240">
        <property type="entry name" value="SANT_CDC5L_II"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45885">
        <property type="entry name" value="CELL DIVISION CYCLE 5-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45885:SF1">
        <property type="entry name" value="CELL DIVISION CYCLE 5-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11831">
        <property type="entry name" value="Myb_Cef"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="HTH myb-type" evidence="15">
        <location>
            <begin position="2"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="14">
        <location>
            <begin position="2"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="15">
        <location>
            <begin position="54"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="14">
        <location>
            <begin position="54"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="113"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="694"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="231"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="550"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="857"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="694"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="720"/>
            <end position="731"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="CRG97352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="909" mass="107310" checksum="3B787DD8C9037D44" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY02</accession>
    <name>A0A1J1GY02_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF155 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00492000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RMD1/sif2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530143.1">
        <property type="nucleotide sequence ID" value="XM_028673718.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY02"/>
    <dbReference type="GeneID" id="39733453"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00492000"/>
    <dbReference type="OMA" id="SQPEHDY"/>
    <dbReference type="OrthoDB" id="242766at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003734">
        <property type="entry name" value="DUF155"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051624">
        <property type="entry name" value="RMD1/Sad1-interacting"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16255">
        <property type="entry name" value="REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16255:SF1">
        <property type="entry name" value="REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02582">
        <property type="entry name" value="DUF155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="318"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="DUF155" evidence="3">
        <location>
            <begin position="116"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="340" mass="40359" checksum="289F5BDFA9D68A68" modified="2017-02-15" version="1">MLSCKKNFFEKNCLKYLSFLYNIKSYHASNKKSVNKIYTQKKIIKRDKLLGNVKPFINEKYDKPEPTVIAYYLNNSLNLNILKNAYENVGSKVLYKEPYLYVESCEYFEQQNSSAVFFKNGCIVIWNMNKKNIKKFLNFCKNYLKLDDNIETYDFEELEVQNVNNKSYVNNSIIYLTNNNNRTTDKISFSFGLLSAVRLNNLEKKIENKLLLENNNIDILKKKIKSSNLDLLSKQLFSSKITLHNLRYELNIEQDILDVPESLWELEYQKKLFLNILNIFDIKQRVDLLNHRLGWTFDYLNSFLDYVNQKHSSRLERIIIIIIGLELILGIMQMIKTFEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY77</accession>
    <name>A0A1J1GY77_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00317300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528768.1">
        <property type="nucleotide sequence ID" value="XM_028672190.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY77"/>
    <dbReference type="GeneID" id="39731706"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00317300"/>
    <dbReference type="OrthoDB" id="374157at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037264">
        <property type="entry name" value="TFIID_NTD2_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160897">
        <property type="entry name" value="Taf5 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="278" mass="33690" checksum="F2959719C16AB66D" modified="2017-02-15" version="1">MYTIDIVNEEKYVQRVGDICGEHYVPVSLPGRYKYNIEDIENILYIWMDKKYEIKNKEYKDLYIFSLIFKETKFSLILCKSRYENNFCTWQILWYAWRDIFRKSFEKNNKYFEKYKNNIIDFQAGCIYLLFLLYFCQHVESNHYAYPLYMSTETINLCLDVTEECEKRNIFKELRFILNFMIDSNSIILSCNDCLSEIYQDRYGAPLHIEKGKLYVENSIEINNVDVQKFFDYFINDIRDLSELCDEQRKKNTLSNTSTYNLLLKLENIKNIINKDNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYC8</accession>
    <name>A0A1J1GYC8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">choline-phosphate cytidylyltransferase</fullName>
            <ecNumber evidence="8">2.7.7.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00512900</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytidylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.15" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530357.1">
        <property type="nucleotide sequence ID" value="XM_028673956.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYC8"/>
    <dbReference type="GeneID" id="39733662"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00512900"/>
    <dbReference type="OMA" id="CSDIDTR"/>
    <dbReference type="OrthoDB" id="17102at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004105">
        <property type="term" value="F:choline-phosphate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031210">
        <property type="term" value="F:phosphatidylcholine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02174">
        <property type="entry name" value="CCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041723">
        <property type="entry name" value="CCT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045049">
        <property type="entry name" value="Pcy1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10739:SF13">
        <property type="entry name" value="CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10739">
        <property type="entry name" value="CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4 11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cytidyltransferase-like" evidence="10">
        <location>
            <begin position="37"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Cytidyltransferase-like" evidence="10">
        <location>
            <begin position="527"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="407"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="407"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG97556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="801" mass="93914" checksum="AA85FE83722ED425" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYJ3</accession>
    <name>A0A1J1GYJ3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA/RNA-binding protein Alba 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00521800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histone-like Alba family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530443.1">
        <property type="nucleotide sequence ID" value="XM_028674051.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYJ3"/>
    <dbReference type="GeneID" id="39733751"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00521800"/>
    <dbReference type="OMA" id="ERRDPNM"/>
    <dbReference type="OrthoDB" id="424402at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.110.20:FF:000003">
        <property type="entry name" value="DNA/RNA-binding protein Alba 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.20">
        <property type="entry name" value="Alba-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036882">
        <property type="entry name" value="Alba-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051958">
        <property type="entry name" value="Alba-like_NAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002775">
        <property type="entry name" value="DNA/RNA-bd_Alba-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13516:SF4">
        <property type="entry name" value="FI09323P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13516">
        <property type="entry name" value="RIBONUCLEASE P SUBUNIT P25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01918">
        <property type="entry name" value="Alba"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82704">
        <property type="entry name" value="AlbA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DNA/RNA-binding protein Alba-like" evidence="6">
        <location>
            <begin position="12"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="201"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="201"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="223"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="246" mass="27056" checksum="05A0CA82F5C48F6B" modified="2017-02-15" version="1">MKKDREPIDEDEMRITSTGRMTNYVNYAAKLLGEEEKKSIKIKATGNAIAKAVTLTEIVKRRFKGLHQITKCGSTIITDQYVSGQDNNEHVVQEKTVSFIEILLSRDQLDTKDAGYQPPLDEKYVKEMTPEEIVNSRGFRGRGFRPRYYRGFRGGRGSGFLRRGGYRGFSERMYEGRNSFRGGRGGGYGGSFGRGGYRSGGGGMGGGRGGYRGGYRGGREGGYRGGNRGGGYRSGRGGYRGGRALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYK9</accession>
    <name>A0A1J1GYK9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ubiquitin-conjugating enzyme, putative</fullName>
            <ecNumber evidence="6">6.3.2.19</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00523400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.19" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530459.1">
        <property type="nucleotide sequence ID" value="XM_028674069.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYK9"/>
    <dbReference type="GeneID" id="39733767"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00523400"/>
    <dbReference type="OMA" id="QERANCT"/>
    <dbReference type="OrthoDB" id="9984419at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd23790">
        <property type="entry name" value="UBCc_UBE2A_2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000054">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="5">
        <location>
            <begin position="4"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="3">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="163" mass="18779" checksum="B5ADD0D810B1B5C4" modified="2017-02-15" version="1">MSNLAKKRLIRDFRKLQMDSPYGISGSPIGNDIMKWRAVIFGPTDTPWEGGTFQLELLFGNEYPNKPPKVKFLTKMFHPNIYMDGNICIDILQKHWSPIYDISAILTSIQSLLSDPNPNSPANQEAALLFVENRIEYNRRIKNCVKESFNFIENKVEEKAQNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYL6</accession>
    <name>A0A1J1GYL6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">OTU-like cysteine protease, putative</fullName>
            <ecNumber evidence="3">3.4.22.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00490800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.22.-" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530131.1">
        <property type="nucleotide sequence ID" value="XM_028673705.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYL6"/>
    <dbReference type="GeneID" id="39733441"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00490800"/>
    <dbReference type="OrthoDB" id="415023at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22771">
        <property type="entry name" value="OTU_plant_OTU7-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050704">
        <property type="entry name" value="Peptidase_C85-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12419">
        <property type="entry name" value="OTU DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12419:SF7">
        <property type="entry name" value="OTU DOMAIN-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02338">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OTU" evidence="2">
        <location>
            <begin position="50"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="769" mass="91696" checksum="4B5C7733EC713959" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYM5</accession>
    <name>A0A1J1GYM5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00491600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530139.1">
        <property type="nucleotide sequence ID" value="XM_028673714.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYM5"/>
    <dbReference type="GeneID" id="39733449"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00491600"/>
    <dbReference type="OMA" id="NLFERWT"/>
    <dbReference type="OrthoDB" id="386332at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="131" mass="15942" checksum="8CF1424E4C1DC1C5" modified="2017-02-15" version="1">MDDYLNEDSVIKHKAWNLHFMDKRKNNKFKYSKKKNMKYNVKWIKKKDNENLFERWIQIKTLNENYNSEEEKEKDETKKQIGRNVLSNNNETRKSYRLNLQSILNENNTKKNYVDPSSDISSEEQENDNNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYZ2</accession>
    <name>A0A1J1GYZ2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CCR4-associated factor 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">CAF1</name>
        <name evidence="2" type="ORF">PGAL8A_00524800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530473.1">
        <property type="nucleotide sequence ID" value="XM_028674084.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733781"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00524800"/>
    <dbReference type="OMA" id="HEDNANG"/>
    <dbReference type="OrthoDB" id="1164111at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030014">
        <property type="term" value="C:CCR4-NOT complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004535">
        <property type="term" value="F:poly(A)-specific ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.10:FF:000048">
        <property type="entry name" value="CCR4-associated factor 1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039637">
        <property type="entry name" value="CNOT7/CNOT8/Pop2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10797">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="811"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1050"/>
            <end position="1215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="827"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="874"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="925"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1050"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1081"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1191"/>
            <end position="1214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1585" mass="181881" checksum="BE96C9D3D1424DA1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZH0</accession>
    <name>A0A1J1GZH0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00364300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529224.1">
        <property type="nucleotide sequence ID" value="XM_028672697.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZH0"/>
    <dbReference type="GeneID" id="39732173"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00364300"/>
    <dbReference type="OMA" id="KYKKCYT"/>
    <dbReference type="OrthoDB" id="360686at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="386"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="406" mass="47730" checksum="A985B268A5572D56" modified="2017-02-15" version="1">MLTDELIKENVKEIFLSYNDMIRDDQSETSVESYKDVNNFLEDSDNESYFTYSNESDSSSIYNSDTTDEKNIKIYSYVSRSFIPKKDKKYKKFHTVSYINNMNSIVNFPLKNYGSILISDKIRKIKNYQWKPPGKNIPSISSIKLSHKKAWDIGKEGCNGLLIENLLESYKKKKLNYIVLDGTNIENFLTVYTHSYQDTIKGVNSSILNTFSFYDLEEAHFLYDIKSIHIYKDIKKKKKTIILKDLNDNFFNAILVCMNEIIIYLKIFNLKKSLLNKSNKKKKKKNLDEEIYFVKSVKNENNLYKNRIKDVISANKRKSIKYNFTDVKNIEKGNVNNLICLDENNDHIKDKLKLSKKFPSNNSEKFCYKYLCDALKKEENELKEFNKNDDNAKNEYTSHTSDSNEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZK2</accession>
    <name>A0A1J1GZK2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">V-type proton ATPase subunit F</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00367600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the V-ATPase F subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529256.1">
        <property type="nucleotide sequence ID" value="XM_028672733.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZK2"/>
    <dbReference type="GeneID" id="39732206"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00367600"/>
    <dbReference type="OMA" id="IIICQHI"/>
    <dbReference type="OrthoDB" id="10261947at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033180">
        <property type="term" value="C:proton-transporting V-type ATPase, V1 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10580:FF:000004">
        <property type="entry name" value="V-type proton ATPase subunit F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10580">
        <property type="entry name" value="ATPase, V1 complex, subunit F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008218">
        <property type="entry name" value="ATPase_V1-cplx_f_g_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005772">
        <property type="entry name" value="ATPase_V1-cplx_fsu_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036906">
        <property type="entry name" value="ATPase_V1_fsu_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01101">
        <property type="entry name" value="V_ATP_synt_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13861:SF2">
        <property type="entry name" value="V-TYPE PROTON ATPASE SUBUNIT F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13861">
        <property type="entry name" value="VACUOLAR ATP SYNTHASE SUBUNIT F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01990">
        <property type="entry name" value="ATP-synt_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015945">
        <property type="entry name" value="ATPase_V1_F_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159468">
        <property type="entry name" value="AtpF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR015945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="128" mass="14676" checksum="8F578C6B1E844D4C" modified="2017-02-15" version="1">MASRRHKFFNETDLKIYIIGDEDSVVGFLLAGIGFRDGLGKKNFFIVNSKTNKTEIEDVFKEYTSKHDCGVILMNQQIADEIRYLVDLHDKILPTILEIPSKDKPFDPNKDSIIQRVKLFFGGDISHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZP7</accession>
    <name>A0A1J1GZP7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Clathrin heavy chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00533700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <location evidence="1">Coated pit</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the clathrin heavy chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530560.1">
        <property type="nucleotide sequence ID" value="XM_028674181.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733870"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00533700"/>
    <dbReference type="OMA" id="WLKEDKX"/>
    <dbReference type="OrthoDB" id="421917at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030132">
        <property type="term" value="C:clathrin coat of coated pit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030130">
        <property type="term" value="C:clathrin coat of trans-Golgi network vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071439">
        <property type="term" value="C:clathrin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032051">
        <property type="term" value="F:clathrin light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006898">
        <property type="term" value="P:receptor-mediated endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000307">
        <property type="entry name" value="Clathrin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.110">
        <property type="entry name" value="Clathrin heavy-chain terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055358">
        <property type="entry name" value="CHCR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000547">
        <property type="entry name" value="Clathrin_H-chain/VPS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012331">
        <property type="entry name" value="Clathrin_H-chain_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016025">
        <property type="entry name" value="Clathrin_H-chain_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022365">
        <property type="entry name" value="Clathrin_H-chain_propeller_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016341">
        <property type="entry name" value="Clathrin_heavy_chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10292:SF1">
        <property type="entry name" value="CLATHRIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10292">
        <property type="entry name" value="CLATHRIN HEAVY CHAIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00637">
        <property type="entry name" value="Clathrin"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01394">
        <property type="entry name" value="Clathrin_propel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002290">
        <property type="entry name" value="Clathrin_H_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00299">
        <property type="entry name" value="CLH"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50989">
        <property type="entry name" value="Clathrin heavy-chain terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50236">
        <property type="entry name" value="CHCR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0168">Coated pit</keyword>
    <keyword evidence="1" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="CHCR" evidence="2">
        <location>
            <begin position="626"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="2">
        <location>
            <begin position="795"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="2">
        <location>
            <begin position="993"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="2">
        <location>
            <begin position="1141"/>
            <end position="1309"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="2">
        <location>
            <begin position="1392"/>
            <end position="1535"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="2">
        <location>
            <begin position="1540"/>
            <end position="1686"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="2">
        <location>
            <begin position="1689"/>
            <end position="1832"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR002290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1945" mass="227496" checksum="21736B7F2F50486F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZY5</accession>
    <name>A0A1J1GZY5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00416100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529384.1">
        <property type="nucleotide sequence ID" value="XM_028672875.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZY5"/>
    <dbReference type="GeneID" id="39732692"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00416100"/>
    <dbReference type="OMA" id="EQMIPQL"/>
    <dbReference type="OrthoDB" id="49395at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116907">
        <property type="entry name" value="Hook domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="644" mass="76087" checksum="021834D9D0509D37" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H007</accession>
    <name>A0A1J1H007_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Queuine tRNA-ribosyltransferase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00064500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028531003.1">
        <property type="nucleotide sequence ID" value="XM_028674674.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H007"/>
    <dbReference type="GeneID" id="39729170"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00064500"/>
    <dbReference type="OrthoDB" id="10249838at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002099">
        <property type="term" value="P:tRNA wobble guanine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.105:FF:000004">
        <property type="entry name" value="Queuine tRNA-ribosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.105">
        <property type="entry name" value="Queuine tRNA-ribosyltransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050076">
        <property type="entry name" value="ArchSynthase1/Queuine_TRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036511">
        <property type="entry name" value="TGT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002616">
        <property type="entry name" value="tRNA_ribo_trans-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00449">
        <property type="entry name" value="tgt_general"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46499">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46499:SF1">
        <property type="entry name" value="QUEUINE TRNA-RIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01702">
        <property type="entry name" value="TGT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51713">
        <property type="entry name" value="tRNA-guanine transglycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA-guanine(15) transglycosylase-like" evidence="4">
        <location>
            <begin position="163"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-guanine(15) transglycosylase-like" evidence="4">
        <location>
            <begin position="281"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="75"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG98206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="715" mass="83744" checksum="1A18E7BB1ACE4B17" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H047</accession>
    <name>A0A1J1H047_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00054800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530910.1">
        <property type="nucleotide sequence ID" value="XM_028674571.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H047"/>
    <dbReference type="GeneID" id="39729073"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00054800"/>
    <dbReference type="OrthoDB" id="390282at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG98113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="160" mass="19120" checksum="23D1AEFA89B2B9DF" modified="2017-02-15" version="1">MIIHLNNKNLFHFILFKKINIIKRDTHTLKKKFHLYDEDLKKSFEKISKGVPPRANINKIIDFLLHSEILSCNWTKLEIIDEIYKRKIDKTLSFHLNVLYGLGSKGIHLNKKGIISPILFLPLLDYDQFKYMVEVMKVADKEKKFMVHKQNEFINNFFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0F6</accession>
    <name>A0A1J1H0F6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00434600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529568.1">
        <property type="nucleotide sequence ID" value="XM_028673079.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0F6"/>
    <dbReference type="GeneID" id="39732878"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00434600"/>
    <dbReference type="OMA" id="NYKVVWT"/>
    <dbReference type="OrthoDB" id="365182at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="563" mass="69229" checksum="797562FF0CEEC708" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0L8</accession>
    <name>A0A1J1H0L8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytoplasmic translation machinery associated protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00465500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529877.1">
        <property type="nucleotide sequence ID" value="XM_028673424.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0L8"/>
    <dbReference type="GeneID" id="39733188"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00465500"/>
    <dbReference type="OMA" id="GREMFYF"/>
    <dbReference type="OrthoDB" id="278280at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032378">
        <property type="entry name" value="ZC3H15/TMA46_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12681:SF0">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12681">
        <property type="entry name" value="ZINC FINGER-CONTAINING PROTEIN P48ZNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16543">
        <property type="entry name" value="DFRP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="141"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="141"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="233"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="49"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="233"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="291"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="335" mass="39884" checksum="13C9029347E16326" modified="2017-02-15" version="1">MPPKKDNKKIEKEKQKIVEDKTFGLKNKNKSKSVQRYIKGVQQQVFQTKKKSCDDKRKEEKEKEKLNQQKLLLNSIYQKTEKVKKINESSTYDPKKSKEAQKIDIYTDIRDAKNEKEDDTIDKWDIHKLTEVINIRHKNINKTDIICKYFLSAVENKQYGWFWVCPNGGDNCKYKHCLPQGYVLKKQETPENEKEEKPLEDIIEEERMKYINNGTPVTLELFKKWKTEREEKKKLKKEEQKEKDKSEKKNKNTVLSGKELFSYDPTLFVDDDNAANTNEYDDLFYDDEEEKKESIEKKNDANGEIKENKNDKREDEVPINSELFIDELDDLDELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H101</accession>
    <name>A0A1J1H101_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00452900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529752.1">
        <property type="nucleotide sequence ID" value="XM_028673283.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H101"/>
    <dbReference type="GeneID" id="39733062"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00452900"/>
    <dbReference type="OMA" id="YCENYLN"/>
    <dbReference type="OrthoDB" id="384906at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="378" mass="44941" checksum="AA5D81743D49009F" modified="2017-02-15" version="1">MSWKQFSRVLSKLLGKQGLKKSRLKFREIKKNFKIVFNLIFGNYFNQILNKPTKGLISNFFVKYIFNTFASLYNKNYKIGDFKLFICHFFLKNKLNGKLAKCKIGTHYTKKKKYKIIKDNISKCLESSYGLEPNEHYIIDMYDETHLHNEYHNTFLLNNKTFSFELDYNTTQMDDYGRINENDRLNSSSYLENDILSFDNIEYDEDEANESIKNCYLYNGYINADTYKNSEEYKFLKNHLKQKKDSIINIEIGIPSEYCDKQIKSESGSECESENKSDINSEENENEDKKMINKKRKKQKKKIYEIYNTETTIKQNIYCANYLNENYSSSYDYASEESSSSRSDFIDKDFYDEYFGDNYGNDFLCHCSVRSYDTFQST</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1M4</accession>
    <name>A0A1J1H1M4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Large subunit rRNA processing RRM protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00479200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530016.1">
        <property type="nucleotide sequence ID" value="XM_028673578.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1M4"/>
    <dbReference type="GeneID" id="39733325"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00479200"/>
    <dbReference type="OMA" id="KCTDEQM"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051945">
        <property type="entry name" value="RRM_MRD1_RNA_proc_ribogen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN 14B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039:SF5">
        <property type="entry name" value="RNA-BINDING PROTEIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="275"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="27"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="135"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="400" mass="46728" checksum="7550482F958EB097" modified="2017-02-15" version="1">MKKNKDKIFGSNTIVIKKKTIEKEKKIIKEKKKKNKIKKENKSKNTIENSTKDTRTNENNTKNLTEDYPKISKKNKKYSIKQNETKKKPTKVSKILKKLSSKNEPKKEKISSVVEFLNKNETIDSKINDKKNDKKITMNINSSNDKELKVSKKPLPQNKDGDKSLEKNKRTVFVGNIPLKNVTGPKLLKILNIKRSLVESIRFRSLPLEEKYANKKKLGVILKKFTDAKDNKNALITLKEEDHVPIILSRNGTVYDGYVLRVNRIGDNSFFNKKKSVCIRNLHKQLNEKDLYELMKDVDEIKGIRILRDNITSCSTGVAFILFKNRSSVKKAIEMFNGKMINNRPIVVQKVLDRNEIDNAKKKNKEIMKKEINKKFKKYRKKKKKYFRKKNRIDNNVETN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H444</accession>
    <name>A0A1J1H444_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="5">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00055700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="5">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530919.1">
        <property type="nucleotide sequence ID" value="XM_028674581.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H444"/>
    <dbReference type="GeneID" id="39729082"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00055700"/>
    <dbReference type="OrthoDB" id="3370at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="109"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="327"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="14"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG98122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="525" mass="62766" checksum="86DB2B071B60334C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLB1</accession>
    <name>A0A1J1GLB1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">60S ribosomal protein L11a, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00082800</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the universal ribosomal protein uL5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525946.1">
        <property type="nucleotide sequence ID" value="XM_028670755.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLB1"/>
    <dbReference type="GeneID" id="39729352"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00082800"/>
    <dbReference type="OMA" id="NPMKELK"/>
    <dbReference type="OrthoDB" id="1734943at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1440.10:FF:000004">
        <property type="entry name" value="60S ribosomal protein L11, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002132">
        <property type="entry name" value="Ribosomal_uL5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031309">
        <property type="entry name" value="Ribosomal_uL5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022803">
        <property type="entry name" value="Ribosomal_uL5_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057266">
        <property type="entry name" value="Ribosomal_uL5_euk/arc-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031310">
        <property type="entry name" value="Ribosomal_uL5_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003258">
        <property type="entry name" value="PRK04219.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11994">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00281">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00673">
        <property type="entry name" value="Ribosomal_L5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002161">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55282">
        <property type="entry name" value="RL5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7 10 13" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL5 N-terminal" evidence="11">
        <location>
            <begin position="7"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL5 C-terminal" evidence="12">
        <location>
            <begin position="64"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG93124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="173" mass="20352" checksum="7DC189E35CA343FE" modified="2017-02-15" version="1">MEKREENVMREIKVNKLVLNICVGESGDRLTRAARVLEQLTEQKPIFGKCRFTIRSFGVRRNEKISCYVTVRGKKALEILEKGLKVKEYELRRKNFSDTGNFGFGIQEHIDLGIKYDPSTGIYGMDFYVHLSRPGYRVTRRRRKRSRISKTHKVTKEDAMKWFQTKFDGILLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLC6</accession>
    <name>A0A1J1GLC6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Trafficking protein particle complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">BET3</name>
        <name evidence="9" type="ORF">PGAL8A_00092000</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">May play a role in vesicular transport from endoplasmic reticulum to Golgi.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 8">Golgi apparatus</location>
            <location evidence="1 8">cis-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the TRAPP small subunits family. BET3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526038.1">
        <property type="nucleotide sequence ID" value="XM_028671777.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLC6"/>
    <dbReference type="GeneID" id="39729444"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00092000"/>
    <dbReference type="OMA" id="QRRPEYH"/>
    <dbReference type="OrthoDB" id="10262857at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030008">
        <property type="term" value="C:TRAPP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048193">
        <property type="term" value="P:Golgi vesicle transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14942">
        <property type="entry name" value="TRAPPC3_bet3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1380.20:FF:000001">
        <property type="entry name" value="Trafficking protein particle complex subunit BET3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.20">
        <property type="entry name" value="Trafficking protein particle complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016721">
        <property type="entry name" value="Bet3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007194">
        <property type="entry name" value="TRAPP_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13048">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04051">
        <property type="entry name" value="TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018293">
        <property type="entry name" value="TRAPP_I_complex_Bet3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="Ligand-binding domain in the NO signalling and Golgi transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 8" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="7 8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR018293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="187" mass="21358" checksum="02396A47EC619768" modified="2017-02-15" version="1">MSKDKYQKHGEAVFSKLEKVNSELLSLTYGALVSQLLKDLELVDEVNEQLEKMGYNIGIRLIEEFLAKSDISFCENFEETVEVIAKVAFKMFLGISGTVNCINRESNIFSIIFDSNPLSDFVELPKSLSSLNYCSLLCGVIKGALEQIRIKVNCYFVKDMLKGDDYYEIYIQLKEVMKEEILNDEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLG9</accession>
    <name>A0A1J1GLG9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">3'-5' exonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00097000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526086.1">
        <property type="nucleotide sequence ID" value="XM_028672311.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729494"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00097000"/>
    <dbReference type="OMA" id="CIHKYYD"/>
    <dbReference type="OrthoDB" id="377911at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="612"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="307"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1848" mass="223681" checksum="B127C089F0D199B8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLH0</accession>
    <name>A0A1J1GLH0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RING zinc finger protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00089200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526010.1">
        <property type="nucleotide sequence ID" value="XM_028671466.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLH0"/>
    <dbReference type="GeneID" id="39729416"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00089200"/>
    <dbReference type="OMA" id="YDNFRCP"/>
    <dbReference type="OrthoDB" id="6105938at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23327">
        <property type="entry name" value="RING FINGER PROTEIN 127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23327:SF51">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR OF YEAST FORM ADHERENCE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="78"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="171"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="721" mass="87265" checksum="C1C0E7DFB51E1A41" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLP0</accession>
    <name>A0A1J1GLP0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00103200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526148.1">
        <property type="nucleotide sequence ID" value="XM_028672999.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLP0"/>
    <dbReference type="GeneID" id="39729557"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00103200"/>
    <dbReference type="OrthoDB" id="333770at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="404"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="439" mass="52688" checksum="323A30EFD9690465" modified="2017-02-15" version="1">MFNLKKNQILLLNYIKIYKRNYSLSKNNYELSFEKEEVSLVNKKKKNIYKKSIFYEELSDKNNIENNINILKIIKNSKIENFSIYDSTLILNYLIKNKKNKEFSNELKNINKVKLSSTLYKDAISKVLKNILEYNPKHIYFFFNKFSDLRDLNSIEIIFLHIFNNHLLYFSLYYLTEITYNIAILNCNFKKAGPILNEFLDYIVLTTIKENKNIKNFEKKITNIITTKGINDKKAIYIKSFKNRIRIKGNNDVSNNIIIHDSKREEMHNQEKTKSNKKKSKFSIDSLSNVMLYKLIYSLAKINHNKDLIKELFVLLIPYIRYIIQNKNYVYSKDRNDILVKIIWSFSFLHIRDINLFVDFSLCIQIIIHELSLKYLKILRNIYENLLIFDELLLDKLEDRINQIEKDSPPSHSQPRKKQFKKKKKRIEITDEIKFKLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLZ5</accession>
    <name>A0A1J1GLZ5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Signal recognition particle SRP9, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00095900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526075.1">
        <property type="nucleotide sequence ID" value="XM_028672187.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLZ5"/>
    <dbReference type="GeneID" id="39729483"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00095900"/>
    <dbReference type="OrthoDB" id="360923at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.720.10">
        <property type="entry name" value="Signal recognition particle alu RNA binding heterodimer, srp9/1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009018">
        <property type="entry name" value="Signal_recog_particle_SRP9/14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039914">
        <property type="entry name" value="SRP9-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039432">
        <property type="entry name" value="SRP9_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12834">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 9 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12834:SF12">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 9 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05486">
        <property type="entry name" value="SRP9-21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54762">
        <property type="entry name" value="Signal recognition particle alu RNA binding heterodimer, SRP9/14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRP9" evidence="1">
        <location>
            <begin position="2"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="99" mass="11559" checksum="CDE5EC86F0C90F9B" modified="2017-02-15" version="1">MSWNDFIHTTRNIISKSPNKTRYVIKLHRPSETIILKVTDSKNSIMYRLSKSDNLKKLEELNSLFLIWGTSENQNETLPLKLNKTIDKASNDQKVKKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM45</accession>
    <name>A0A1J1GM45_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Dicarboxylate/tricarboxylate carrier, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00117100</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526287.1">
        <property type="nucleotide sequence ID" value="XM_028674544.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM45"/>
    <dbReference type="GeneID" id="39729696"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00117100"/>
    <dbReference type="OMA" id="MMDTSTM"/>
    <dbReference type="OrthoDB" id="756301at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000009">
        <property type="entry name" value="Mitochondrial 2-oxoglutarate/malate carrier protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050391">
        <property type="entry name" value="Mito_Metabolite_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45618">
        <property type="entry name" value="MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="33"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="124"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="222"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG93465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="318" mass="35618" checksum="539BC8B81AEBC2FD" modified="2017-02-15" version="1">MNKETAKYDLENSSIGELKKIKNEDKSTFEKVKPFMVGGVSGMFATFCIQPLDMIKVRIQLNAEGKNVVRNPFVVAKDIIKNEGVLSLYKGLDAGLTRQIVYTTARLGLFRTFSDMVKKEGEPLPFYKKCFCALAAGGLGAFIGNPADLSLIRLQADNTLPKELKRNYTGVFNALYRISKEEGILSLWKGSVPTIARAMSLNLGMLSTYDQSKEYLEKHLGSGMKTNLVASVISGFFAVTLSLPFDFVKTCMQKMKVDPVTKKMPYKNMLDCAYKMYKKGGISIFYSSYTTYYVRIAPHAMITLITVDYINNILKKFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GME3</accession>
    <name>A0A1J1GME3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RAP protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00127600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526391.1">
        <property type="nucleotide sequence ID" value="XM_028674796.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GME3"/>
    <dbReference type="GeneID" id="39729801"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00127600"/>
    <dbReference type="OrthoDB" id="385235at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035770">
        <property type="term" value="C:ribonucleoprotein granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000963">
        <property type="term" value="P:mitochondrial RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044528">
        <property type="term" value="P:regulation of mitochondrial mRNA stability"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050870">
        <property type="entry name" value="FAST_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013584">
        <property type="entry name" value="RAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058917">
        <property type="entry name" value="RESC6_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21228">
        <property type="entry name" value="FAST LEU-RICH DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21228:SF40">
        <property type="entry name" value="LD45607P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08373">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26188">
        <property type="entry name" value="RESC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00952">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51286">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RAP" evidence="1">
        <location>
            <begin position="1076"/>
            <end position="1132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1274" mass="151712" checksum="5F107C5372B40774" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GME6</accession>
    <name>A0A1J1GME6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00123900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526354.1">
        <property type="nucleotide sequence ID" value="XM_028674754.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GME6"/>
    <dbReference type="GeneID" id="39729764"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00123900"/>
    <dbReference type="OrthoDB" id="369888at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="5"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="262" mass="31036" checksum="824B82B276340CF9" modified="2017-02-15" version="1">MDRGLEKLLNQINDLESKNRLINIHIEELKTTESELQKKEKELISEIEYICKQLKCMEKEEIELNNDISRVNLICKNVEATLHNEFVKVEISAQKINQVEEYYEENDKKINEELMKSDAKIKKCLLNLNDTNDDFNKLKEIKNDHFLLNHISLEELYEIYEETKEKYQNSSFKNQCDQIVIVDYKTYTYFCNPTHLLHMINILIEKIKQSNNDPHFNLTSMGNYCGLKEQKTSEQIENFGLSELNKIMISHYKSKKINVNSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMG8</accession>
    <name>A0A1J1GMG8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00134500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526462.1">
        <property type="nucleotide sequence ID" value="XM_028674874.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMG8"/>
    <dbReference type="GeneID" id="39729870"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00134500"/>
    <dbReference type="OMA" id="YNFCKGV"/>
    <dbReference type="OrthoDB" id="377690at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="473"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="615"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="836"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="907"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="473"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="495"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="948" mass="113639" checksum="09FC488EF5F9F3C6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMR0</accession>
    <name>A0A1J1GMR0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00143400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526550.1">
        <property type="nucleotide sequence ID" value="XM_028674972.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMR0"/>
    <dbReference type="GeneID" id="39729958"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00143400"/>
    <dbReference type="OMA" id="FNTKYAW"/>
    <dbReference type="OrthoDB" id="377319at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="556" mass="66983" checksum="F0A7E732D0AC3EFB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN42</accession>
    <name>A0A1J1GN42_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">CDPK2</name>
        <name evidence="19" type="ORF">PGAL8A_00139100</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526507.1">
        <property type="nucleotide sequence ID" value="XM_028674925.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN42"/>
    <dbReference type="GeneID" id="39729915"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00139100"/>
    <dbReference type="OMA" id="YMTTRVG"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05117">
        <property type="entry name" value="STKc_CAMK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000315">
        <property type="entry name" value="Calcium-dependent protein kinase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000475">
        <property type="entry name" value="Calcium-dependent protein kinase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000003">
        <property type="entry name" value="Calmodulin A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050205">
        <property type="entry name" value="CDPK_Ser/Thr_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24349">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0106">Calcium</keyword>
    <keyword evidence="9 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5 19" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="17">
        <location>
            <begin position="63"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="18">
        <location>
            <begin position="361"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="18">
        <location>
            <begin position="433"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="18">
        <location>
            <begin position="471"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00024334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="CRG93685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="506" mass="58169" checksum="3F6474EC2BB070A3" modified="2017-02-15" version="1">MGNLILINKLRKKYNFIKKESKEKNEILVEENTNNLNNSTREGSTFERENFILSHAGKLEDKYVIDKKLGQGTYGCVYKGINKTTRQYYAIKGEKKDRLKNINRFFQEIEIMKKLDHPNIVKLYETFEDDNFIFLVMELCSGKELFDSIIEQGSFTEKNAATIMKQIFSAIFYLHSLNIVHRDIKPENFLFQSESKDSLLKIIDFGLSKKLYEGEFTTTKAGTPYYVAPQVLEGKYDKKCDIWSSGIIMYTLLCGYPPFYGDTDNEVLKKVKQGEFCFYENDWGNISLDAKDLITNLLKYNPDERCTIEEALNHPWITQMTKSKKNIALSSSLLNNLKNFKKENQLKKAALTIIAQHLCDVEINNLRNIFIALDVDNSGTLSSQEILDGLKKIGYQKIPPDIHQILKDIDSNGSGQIHYTDFLAATIDKRTYLKEEICLIPFKVFDIDGNGKISIEELKKIFGKADVKNSLGDKAIDSLLQEIDLNGDGEIDFNEFMLMMKKKNRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN55</accession>
    <name>A0A1J1GN55_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">leucine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Leucyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PGAL8A_00151300</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>tRNA(Leu) + L-leucine + ATP = L-leucyl-tRNA(Leu) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:11688"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.4" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526626.1">
        <property type="nucleotide sequence ID" value="XM_028675057.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730037"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00151300"/>
    <dbReference type="OMA" id="KFIEWQF"/>
    <dbReference type="OrthoDB" id="10249672at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004823">
        <property type="term" value="F:leucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006429">
        <property type="term" value="P:leucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000203">
        <property type="entry name" value="Leucine--tRNA ligase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="entry name" value="Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004493">
        <property type="entry name" value="Leu-tRNA-synth_Ia_arc/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45794:SF1">
        <property type="entry name" value="LEUCINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45794">
        <property type="entry name" value="LEUCYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="12">
        <location>
            <begin position="14"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="12">
        <location>
            <begin position="174"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Leucyl tRNA synthetase" evidence="14">
        <location>
            <begin position="860"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="13">
        <location>
            <begin position="955"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1080"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1096"/>
            <end position="1126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1127"/>
            <end position="1141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF09334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG93804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1287" mass="152052" checksum="B901C19C79135E75" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="39" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN63</accession>
    <name>A0A1J1GN63_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">[histone H3]-lysine(4) N-trimethyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.354</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="primary">SET1</name>
        <name evidence="24" type="ORF">PGAL8A_00158200</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + 3 S-adenosyl-L-homocysteine + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:60260"/>
            <dbReference type="Rhea" id="RHEA-COMP:15537"/>
            <dbReference type="Rhea" id="RHEA-COMP:15547"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="EC" id="2.1.1.354"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6),N(6),N(6)-trimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:60272"/>
            <dbReference type="Rhea" id="RHEA-COMP:15537"/>
            <dbReference type="Rhea" id="RHEA-COMP:15540"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
            <dbReference type="ChEBI" id="CHEBI:61976"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>N(6)-methyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:60268"/>
            <dbReference type="Rhea" id="RHEA-COMP:15540"/>
            <dbReference type="Rhea" id="RHEA-COMP:15543"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61929"/>
            <dbReference type="ChEBI" id="CHEBI:61976"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.354" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526695.1">
        <property type="nucleotide sequence ID" value="XM_028675133.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730107"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00158200"/>
    <dbReference type="OMA" id="CCESIYN"/>
    <dbReference type="OrthoDB" id="308383at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048188">
        <property type="term" value="C:Set1C/COMPASS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140999">
        <property type="term" value="F:histone H3K4 trimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04369">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15489">
        <property type="entry name" value="PHD_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10518">
        <property type="entry name" value="SET_SETD1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034732">
        <property type="entry name" value="EPHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044570">
        <property type="entry name" value="Set1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45814">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SETD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45814:SF2">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SETD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51805">
        <property type="entry name" value="EPHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50868">
        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10 15" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="9" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="17" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 24" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 24" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 16" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="20">
        <location>
            <begin position="1767"/>
            <end position="1825"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="19">
        <location>
            <begin position="1858"/>
            <end position="1908"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="23">
        <location>
            <begin position="5321"/>
            <end position="5436"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="21">
        <location>
            <begin position="6266"/>
            <end position="6383"/>
        </location>
    </feature>
    <feature type="domain" description="Post-SET" evidence="22">
        <location>
            <begin position="6391"/>
            <end position="6407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="519"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1512"/>
            <end position="1595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="3262"/>
            <end position="3296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="4027"/>
            <end position="4051"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="4160"/>
            <end position="4238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="4511"/>
            <end position="4644"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="17">
        <location>
            <begin position="690"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="17">
        <location>
            <begin position="5554"/>
            <end position="5581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="18">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="13"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="519"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="1535"/>
            <end position="1553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="1554"/>
            <end position="1568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="1569"/>
            <end position="1595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="3268"/>
            <end position="3281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="4027"/>
            <end position="4050"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="4170"/>
            <end position="4185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="18">
        <location>
            <begin position="4192"/>
            <end position="4208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="18">
        <location>
            <begin position="4209"/>
            <end position="4223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="4225"/>
            <end position="4238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="4529"/>
            <end position="4538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="4545"/>
            <end position="4558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="4569"/>
            <end position="4578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="4585"/>
            <end position="4610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS51805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="CRG93874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="6407" mass="762635" checksum="3F2C0C0E3486360C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN97</accession>
    <name>A0A1J1GN97_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00143900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526555.1">
        <property type="nucleotide sequence ID" value="XM_028674977.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN97"/>
    <dbReference type="GeneID" id="39729963"/>
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    <dbReference type="OMA" id="CISACKR"/>
    <dbReference type="OrthoDB" id="385933at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="267"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="417" mass="50178" checksum="89C968DC23FDDEC8" modified="2017-02-15" version="1">MEIKKKKETNNNRKVSESKSKLSDILLKKNHIENYINYSLKENENSYKQNKINNMKDNKVDKNALEIQLKKLTEHLYSLKFKLEKEKKKEKKKKHCIINNIDEPKEKDITTKNRKDLIISKKNHDITERVFPNDKLVHNNTEREISMTKYIPELIKTIEIYKNRTLEEQRNKKYIIEKYENILRNIKKQHIDEISEIKNNILEDVDFLIQKYRKIALELLEITKKKEKEKKEEQKKITEVCINACKKFEEDVKNKAKISLEEYKSYMLTLINNVKKEKEALEKKINELKKKTEEEKCHTEKRVFHACENKIKEEHNLNKELKNRLVLQKEEQNVLINNIYSKVDKQIKIYEENIIKIFHNILINNNINMSISELCNCIKDTMDEQYKNDDLDNSIKNQDKVEEKLKIKYGFVSVFDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GND5</accession>
    <name>A0A1J1GND5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00166200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526775.1">
        <property type="nucleotide sequence ID" value="XM_028675221.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730188"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00166200"/>
    <dbReference type="OMA" id="FLQCQIY"/>
    <dbReference type="OrthoDB" id="381907at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052003">
        <property type="entry name" value="HR_DNA-Binding_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15361:SF5">
        <property type="entry name" value="C3H1-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15361">
        <property type="entry name" value="RAD51/NUKS-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1509"/>
            <end position="1536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2527"/>
            <end position="2553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2959"/>
            <end position="3037"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3568"/>
            <end position="3630"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="616"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3170"/>
            <end position="3213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1511"/>
            <end position="1525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="2996"/>
            <end position="3028"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="3568"/>
            <end position="3577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="3578"/>
            <end position="3597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="3606"/>
            <end position="3624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3954" mass="473745" checksum="95E0D29DBA60A2DE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNE0</accession>
    <name>A0A1J1GNE0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00169200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526806.1">
        <property type="nucleotide sequence ID" value="XM_028670012.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730219"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00169200"/>
    <dbReference type="OMA" id="NIEFMHL"/>
    <dbReference type="OrthoDB" id="376529at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="262"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1981" mass="239942" checksum="FE21EECD6C635680" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNL1</accession>
    <name>A0A1J1GNL1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phospholipase, putative</fullName>
            <ecNumber evidence="2">2.3.1.43</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">PL</name>
        <name evidence="2" type="ORF">PGAL8A_00157800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.43" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526691.1">
        <property type="nucleotide sequence ID" value="XM_028675129.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNL1"/>
    <dbReference type="GeneID" id="39730103"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00157800"/>
    <dbReference type="OMA" id="NPTTYLI"/>
    <dbReference type="OrthoDB" id="190846at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004607">
        <property type="term" value="F:phosphatidylcholine-sterol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003386">
        <property type="entry name" value="LACT/PDAT_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11440">
        <property type="entry name" value="LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02450">
        <property type="entry name" value="LCAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="723" mass="83377" checksum="866B302611F6305D" modified="2017-02-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNY1</accession>
    <name>A0A1J1GNY1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA-directed RNA polymerase II, putative</fullName>
            <ecNumber evidence="7">2.7.7.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00171300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526827.1">
        <property type="nucleotide sequence ID" value="XM_028670035.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNY1"/>
    <dbReference type="GeneID" id="39730240"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00171300"/>
    <dbReference type="OMA" id="VRDRGYF"/>
    <dbReference type="OrthoDB" id="248779at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006362">
        <property type="term" value="P:transcription elongation by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042797">
        <property type="term" value="P:tRNA transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1340.10:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerases I, II, and III subunit RPABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.940.20:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerases I, II, and III subunit RPABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1340.10">
        <property type="entry name" value="RNA polymerase, Rpb5, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.940.20">
        <property type="entry name" value="RPB5-like RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00025">
        <property type="entry name" value="RNApol_Rpo5_RPB5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014381">
        <property type="entry name" value="Arch_Rpo5/euc_Rpb5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005571">
        <property type="entry name" value="RNA_pol_Rpb5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036710">
        <property type="entry name" value="RNA_pol_Rpb5_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000783">
        <property type="entry name" value="RNA_pol_subH/Rpb5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035913">
        <property type="entry name" value="RPB5-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007129">
        <property type="entry name" value="PRK09570.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10535">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10535:SF0">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01191">
        <property type="entry name" value="RNA_pol_Rpb5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03871">
        <property type="entry name" value="RNA_pol_Rpb5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000747">
        <property type="entry name" value="RPB5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53036">
        <property type="entry name" value="Eukaryotic RPB5 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55287">
        <property type="entry name" value="RPB5-like RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNA polymerase Rpb5 N-terminal" evidence="6">
        <location>
            <begin position="3"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase subunit H/Rpb5 C-terminal" evidence="5">
        <location>
            <begin position="132"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG94006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="205" mass="24100" checksum="F802A76F0D6F4E9A" modified="2017-02-15" version="1">MEDPVTRFYKCRKTCCEMLEDRGYIITPREKLENFTAFKEIFEENEKLRSKMTIITSHKNDSNNKIIVYFADEIKKTGVKPLRELTEKMDEKSIQRAILVTQNTLTPFARDAIKEAAPRHIIENFLDTELLVNITKHELVPRHIPLSSEEKRNLLQRYKIKENKLPRIQDVDPVCRYFGLSKGQVVKIIRPSETAGRYVTYRLVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNZ0</accession>
    <name>A0A1J1GNZ0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">E3 ubiquitin-protein ligase, putative</fullName>
            <ecNumber evidence="9">6.3.2.19</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00388200</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.19" evidence="9"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526999.1">
        <property type="nucleotide sequence ID" value="XM_028670226.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNZ0"/>
    <dbReference type="GeneID" id="39732412"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00388200"/>
    <dbReference type="OrthoDB" id="302966at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16536">
        <property type="entry name" value="RING-HC_RNF10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039739">
        <property type="entry name" value="MAG2/RNF10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12983:SF9">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12983">
        <property type="entry name" value="RING FINGER 10 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="237"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="720"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="721"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="738"/>
            <end position="750"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="825" mass="98002" checksum="A3BC67774DC1FB99" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP20</accession>
    <name>A0A1J1GP20_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dynamin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00393700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527054.1">
        <property type="nucleotide sequence ID" value="XM_028670286.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP20"/>
    <dbReference type="GeneID" id="39732467"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00393700"/>
    <dbReference type="OrthoDB" id="372168at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="756"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1025"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1078"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="domain" description="Dynamin N-terminal" evidence="4">
        <location>
            <begin position="290"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="49"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="692"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="51"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="74"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1146" mass="137530" checksum="8096ABA24B43E92E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP21</accession>
    <name>A0A1J1GP21_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Mitochondrial import inner membrane translocase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">TIM9</name>
        <name evidence="10" type="ORF">PGAL8A_00175100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion inner membrane</location>
            <topology evidence="8">Peripheral membrane protein</topology>
            <orientation evidence="8">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the small Tim family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526865.1">
        <property type="nucleotide sequence ID" value="XM_028670076.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP21"/>
    <dbReference type="GeneID" id="39730278"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00175100"/>
    <dbReference type="OMA" id="QDFLRMY"/>
    <dbReference type="OrthoDB" id="1551503at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.810">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit tim13 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050673">
        <property type="entry name" value="Mito_inner_translocase_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004217">
        <property type="entry name" value="Tim10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035427">
        <property type="entry name" value="Tim10-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13172">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM9B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02953">
        <property type="entry name" value="zf-Tim10_DDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144122">
        <property type="entry name" value="Tim10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4 8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0811">Translocation</keyword>
    <keyword evidence="1 8" id="KW-0813">Transport</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Tim10-like" evidence="9">
        <location>
            <begin position="23"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG94044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="92" mass="10931" checksum="0704A7C95702358C" modified="2017-02-15" version="1">MEKSLDLSNFNKNDREKILRKINKAEYEDTMSTYNSIVERCFNECITSFRSKQLDNNENNCILTCVKKFSIFSQRIGMKFTQNLNNEMQKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP51</accession>
    <name>A0A1J1GP51_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Triosephosphate isomerase</fullName>
            <ecNumber evidence="4">5.3.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00397500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:18585"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="5.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the triosephosphate isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.1" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527092.1">
        <property type="nucleotide sequence ID" value="XM_028670329.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP51"/>
    <dbReference type="GeneID" id="39732505"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00397500"/>
    <dbReference type="OMA" id="GNWKCYL"/>
    <dbReference type="OrthoDB" id="6715177at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00189"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004807">
        <property type="term" value="F:triose-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046166">
        <property type="term" value="P:glyceraldehyde-3-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00311">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035990">
        <property type="entry name" value="TIM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000652">
        <property type="entry name" value="Triosephosphate_isomerase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139">
        <property type="entry name" value="TRIOSEPHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139:SF2">
        <property type="entry name" value="TRIOSEPHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00121">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51351">
        <property type="entry name" value="Triosephosphate isomerase (TIM)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51440">
        <property type="entry name" value="TIM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="4" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="3 4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG94271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="348" mass="40077" checksum="A4993EBACD1922B2" modified="2017-02-15" version="1">MQKKILLLYIYLFNLYYIKLSNCLSEYLYKLKIRKRYFISPKCILKVTKINSDDKYKLSKIKIKHANNKKLIKTYSLINSNIGEIKKKKKIIIGNWKCYLSKEQAYKLIDTITQIKYSSYIDLIISPNLLYIPYLQQKIKENNSKIITCSQDVSLVNGFGPFTGETTAKLIYDFGNKYTIIGHSERKKGFYNNVETIEQTVLKVYNAIHSKLKVILCVGEDYDYTNFHLFSSKIKELLSIIKKKISKNEMKNIIIAFEPNFAIGTGKSVSYNILNDCCLDIKKNIANEISPQISDDISIVFGGSINKSNMKNYIGNTISDGFLIGKASLDETFIDIIKYVDQYVLSNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPD2</accession>
    <name>A0A1J1GPD2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00084700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525965.1">
        <property type="nucleotide sequence ID" value="XM_028670965.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPD2"/>
    <dbReference type="GeneID" id="39729371"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00084700"/>
    <dbReference type="OMA" id="FILAICE"/>
    <dbReference type="OrthoDB" id="372911at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="776"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="813"/>
            <end position="831"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="840" mass="101890" checksum="2CBB7C1142D8264E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPE8</accession>
    <name>A0A1J1GPE8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Hypoxanthine phosphoribosyltransferase</fullName>
            <ecNumber evidence="19">2.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="primary">HGPRT</name>
        <name evidence="21" type="ORF">PGAL8A_00388600</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to the N(9) of hypoxanthine, guanine or xanthine, leading to IMP, GMP and XMP, respectively. Plays a central role in the generation of purine nucleotides through the purine salvage pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>GMP + diphosphate = guanine + 5-phospho-alpha-D-ribose 1-diphosphate</text>
            <dbReference type="Rhea" id="RHEA:25424"/>
            <dbReference type="ChEBI" id="CHEBI:16235"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="EC" id="2.4.2.8"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="14">
            <dbReference type="Rhea" id="RHEA:25426"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate</text>
            <dbReference type="Rhea" id="RHEA:17973"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="2.4.2.8"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="15">
            <dbReference type="Rhea" id="RHEA:17975"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>XMP + diphosphate = xanthine + 5-phospho-alpha-D-ribose 1-diphosphate</text>
            <dbReference type="Rhea" id="RHEA:10800"/>
            <dbReference type="ChEBI" id="CHEBI:17712"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.22"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="16">
            <dbReference type="Rhea" id="RHEA:10802"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 19">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Purine metabolism; GMP biosynthesis via salvage pathway; GMP from guanine: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 19">Purine metabolism; IMP biosynthesis via salvage pathway; IMP from hypoxanthine: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="18">Purine metabolism; XMP biosynthesis via salvage pathway; XMP from xanthine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 19">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 19">Belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.8" evidence="19"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527003.1">
        <property type="nucleotide sequence ID" value="XM_028670230.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPE8"/>
    <dbReference type="GeneID" id="39732416"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00388600"/>
    <dbReference type="OMA" id="YQAYEIS"/>
    <dbReference type="OrthoDB" id="9449045at2759"/>
    <dbReference type="UniPathway" id="UPA00591">
        <property type="reaction ID" value="UER00648"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052657">
        <property type="term" value="F:guanine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004422">
        <property type="term" value="F:hypoxanthine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000310">
        <property type="term" value="F:xanthine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032263">
        <property type="term" value="P:GMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006178">
        <property type="term" value="P:guanine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046100">
        <property type="term" value="P:hypoxanthine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032264">
        <property type="term" value="P:IMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000064">
        <property type="entry name" value="Hypoxanthine phosphoribosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050408">
        <property type="entry name" value="HGPRT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005904">
        <property type="entry name" value="Hxn_phspho_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01203">
        <property type="entry name" value="HGPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43340:SF1">
        <property type="entry name" value="HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43340">
        <property type="entry name" value="HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 19" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 19 21" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="13 19" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10 19" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 19" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 19 21" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="20">
        <location>
            <begin position="52"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00052714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00054537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00060716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU364099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="CRG94182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="232" mass="26847" checksum="D1FE0FBCB52FFA5A" modified="2017-02-15" version="1">MMKIPNNPGAGENALEPIYIKDDDGYDIDAFLVPVHYKNYITKVLIPNGVLKNRIEKLAFDIKRVYKNEEFHIICLLKGSRGFFSALLKYLNRIHNYSSSESSKHLYVEHYVRVKSYCNDKSLDRLEIVSEDLSCLKDKHVLIVEDIIDTGKTLLKFCDYLKKFEVKTVAVACLFIKRTPLWNGFKADFVGFSIPDGFVVGYSLDYNEIFRDLEHLCLVNEEGIKKFKDVKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPP9</accession>
    <name>A0A1J1GPP9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">DUF1682 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00397400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527091.1">
        <property type="nucleotide sequence ID" value="XM_028670328.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPP9"/>
    <dbReference type="GeneID" id="39732504"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00397400"/>
    <dbReference type="OMA" id="FRRHYCY"/>
    <dbReference type="OrthoDB" id="10039147at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032469">
        <property type="term" value="P:endoplasmic reticulum calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012879">
        <property type="entry name" value="CCDC47"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12883">
        <property type="entry name" value="ADIPOCYTE-SPECIFIC PROTEIN 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12883:SF0">
        <property type="entry name" value="PAT COMPLEX SUBUNIT CCDC47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07946">
        <property type="entry name" value="CCDC47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="352"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="352"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG94270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="397" mass="47690" checksum="FD91FFEB64E035BD" modified="2017-02-15" version="1">MRKFTTLFLIFTIYLSFYLICSNDIFDDIIIIEESDELNSSDIDPLKTSGDENIVDNTNNIKEIMFKWTGENEKLFYYKIILFICILIIAILNGIIGKKKNKFVALYWLRSCKDIFIENFAKIGNEKSFLLEKSYDNYEFFCTGRKNCNFYLVNLNLSKRQCIWRYYVLHYFIKQNDTMNIAINFEKLDKNILCIYKKNQKKQVENAFPILNKYTKFINKKELKEIYDVKGDSSEITDLVLSGRILNFINSHDKYINYICITDIPLYDYEEKTNDKKNENNKTEKHKYCYLNFIIPKNVEDLRKLINFSIYMIDACHCIELSEKVRDHVKKLRSIVEKEDIKRKQELKEIQEKKKAKKIQEEKEKIDKMSAEQQRKYEEKKKKKNLKKIKKIKVIKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPV6</accession>
    <name>A0A1J1GPV6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic peptide chain release factor subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00403000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Heterodimer of two subunits, one of which binds GTP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic release factor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527147.1">
        <property type="nucleotide sequence ID" value="XM_028670390.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPV6"/>
    <dbReference type="GeneID" id="39732560"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00403000"/>
    <dbReference type="OMA" id="GPGTEKM"/>
    <dbReference type="OrthoDB" id="10254527at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003747">
        <property type="term" value="F:translation release factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.60:FF:000001">
        <property type="entry name" value="Eukaryotic peptide chain release factor subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.960.10:FF:000002">
        <property type="entry name" value="Eukaryotic peptide chain release factor subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.30:FF:000006">
        <property type="entry name" value="Peptide chain release factor subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.960.10">
        <property type="entry name" value="eRF1 domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.60">
        <property type="entry name" value="eRF1 domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042226">
        <property type="entry name" value="eFR1_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024049">
        <property type="entry name" value="eRF1_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005141">
        <property type="entry name" value="eRF1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005142">
        <property type="entry name" value="eRF1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005140">
        <property type="entry name" value="eRF1_Pelota-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004403">
        <property type="entry name" value="Peptide_chain-rel_eRF1/aRF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03676">
        <property type="entry name" value="aRF1_eRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10113">
        <property type="entry name" value="PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03463">
        <property type="entry name" value="eRF1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03464">
        <property type="entry name" value="eRF1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03465">
        <property type="entry name" value="eRF1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01194">
        <property type="entry name" value="eRF1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55481">
        <property type="entry name" value="N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53137">
        <property type="entry name" value="Translational machinery components"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="eRF1/Pelota-like N-terminal" evidence="7">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="427" mass="48072" checksum="68582AA93607FAE3" modified="2017-02-15" version="1">MDDHDANVEQWKIKRLIKKLENAKGNGTSMISLIIKNKDEVSRINKMLADELGTASNIKSRVNRLSVLSAITSTQQKLKLYNKTPPKGLVVYCGTVITEDGKEKKMSIDFEPFRPINTSLYLCDNKFHVEALKELLESDDKFGFIIVDGNGALFGTIQGNTREVIRRFTVDLPKKHGRGGQSALRFARLRLEKRHNYVRKVAEVATSVFITNDKINVTGIVLAGSADFKNDLLNSDMFDPRLSSKVIKIVDISYGGDNGFNQAIELSAEALQNVKFIQEKKLIGKFFEEIAQDTGKVVYGIDDTLKALEIGAVELLIVYEGLDIIRLTTRNNITNQTKTMHISPNDEKQESLYKENNVELEVIEKISLTDWVINNYKKFGASLDFVTNKSQEGAQFQKGFGGFGGLLRYKLDFNIYDEDVESDAELF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ35</accession>
    <name>A0A1J1GQ35_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00084200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525960.1">
        <property type="nucleotide sequence ID" value="XM_028670910.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729366"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00084200"/>
    <dbReference type="OMA" id="ANEYEYQ"/>
    <dbReference type="OrthoDB" id="370976at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031431">
        <property type="term" value="C:Dbf4-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043539">
        <property type="term" value="F:protein serine/threonine kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010571">
        <property type="term" value="P:positive regulation of nuclear cell cycle DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901987">
        <property type="term" value="P:regulation of cell cycle phase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051590">
        <property type="entry name" value="Replication_Regulatory_Kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15375">
        <property type="entry name" value="ACTIVATOR OF S-PHASE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15375:SF26">
        <property type="entry name" value="PROTEIN CHIFFON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="861"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="885"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1548"/>
            <end position="1570"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1678"/>
            <end position="1695"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2498"/>
            <end position="2521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2533"/>
            <end position="2554"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2560"/>
            <end position="2580"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1862"/>
            <end position="1920"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2117"/>
            <end position="2142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2663"/>
            <end position="2685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1862"/>
            <end position="1880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1881"/>
            <end position="1893"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1899"/>
            <end position="1920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="2121"/>
            <end position="2131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2663"/>
            <end position="2677"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2725" mass="332165" checksum="054A0830995E1D39" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ53</accession>
    <name>A0A1J1GQ53_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00204900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527468.1">
        <property type="nucleotide sequence ID" value="XM_028670746.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ53"/>
    <dbReference type="GeneID" id="39730576"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00204900"/>
    <dbReference type="OMA" id="KSDEANW"/>
    <dbReference type="OrthoDB" id="371385at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="303"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="343" mass="41030" checksum="85559D43FD637B78" modified="2017-02-15" version="1">MATKIRYNVHTTNKYSVFDSDNSEEETENKNLKESTKNENNDMYEKIIDNSNEIKKSNELKSNSPVNKEYNAKKPTNQHNDRYKFTIPTLNEVNENSYRNYRDNFHSRGNIRNKFARKRGGGYSNVPTSAIGNNNFYRGSRNYDYKMNIDRRNYNNAYNYNKFDFREKMHNEYNENSCKYDNIKRENILDLKNKNCDENIKATRKHESVTIDYDLYRRQQEKKLNSNKTVESTDKKKKKNEMNNEKSNKISNNTKRNDIDEENKTDHPKRKAINVYQYILEEGGRVDRIPGFRRSFRNFRKGDENNWPNKNEKTKMPIDEKIFKKRDPPNINDTRAFPSLTSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ85</accession>
    <name>A0A1J1GQ85_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Major facilitator superfamily, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00200000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527418.1">
        <property type="nucleotide sequence ID" value="XM_028670691.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ85"/>
    <dbReference type="GeneID" id="39730526"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00200000"/>
    <dbReference type="OMA" id="IGMYLFY"/>
    <dbReference type="OrthoDB" id="370281at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23504:SF31">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="376"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="407"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="434"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="474"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="499"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG94603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="532" mass="62321" checksum="3055B0745E9F8068" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQC5</accession>
    <name>A0A1J1GQC5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00190100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000027">
        <property type="protein sequence ID" value="CRG94504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527321.1">
        <property type="nucleotide sequence ID" value="XM_028670583.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQC5"/>
    <dbReference type="GeneID" id="39730426"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00190100"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006496">
        <property type="entry name" value="CHP01606_Plasmodium_spp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09688">
        <property type="entry name" value="Wx5_PLAF3D7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="330"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="179"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="435" mass="51991" checksum="BE81AE848822AE3B" modified="2017-02-15" version="1">MKTFTLYMKISTLFLLIWMFQFFYNYDSSKSLLDQNTLNIKSCLNYERMLAEGSTSECEEQSDAEEFVEENSSDEEDSEVKDVLALSKDVKDRWSKLIDKMWEQYQNETSMMSKRWRGRKWHIDWHIISSKKINDLHTLILELGKPSEERRELIDKTFKELQEDFSKFLHDCKEEWKKQPKQKKKVKTRKRKLRKTNAPVKEGKIEGKKDFETLSKENISYKDKMEGKKDFETLSKENISYKDKMEGKKDFETLSKENISYKDKIEGKDFETLLKEKISYKDKIEGKKDFETLSKENISYKDKIEGKKDFETLSKENISYKDKIEGKKDFETLSKENINYEDKIEEKKEDHTKKCQVSLNPQEAKWIDDLKKTLENLQKKESKQLEEANDKYKGEDFISNATTIMKNNNDYWTNYLRVKINQLKDQYGLKGYDAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQG0</accession>
    <name>A0A1J1GQG0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">aspartate--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Aspartyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PGAL8A_00098800</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>tRNA(Asp) + L-aspartate + ATP = L-aspartyl-tRNA(Asp) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19649"/>
            <dbReference type="Rhea" id="RHEA-COMP:9660"/>
            <dbReference type="Rhea" id="RHEA-COMP:9678"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.12" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526104.1">
        <property type="nucleotide sequence ID" value="XM_028672510.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQG0"/>
    <dbReference type="GeneID" id="39729512"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00098800"/>
    <dbReference type="OMA" id="HYSEEVI"/>
    <dbReference type="OrthoDB" id="372395at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017101">
        <property type="term" value="C:aminoacyl-tRNA synthetase multienzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006422">
        <property type="term" value="P:aspartyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04320">
        <property type="entry name" value="AspRS_cyto_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00776">
        <property type="entry name" value="AsxRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000038">
        <property type="entry name" value="Aspartate--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02075">
        <property type="entry name" value="Asp_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004523">
        <property type="entry name" value="Asp-tRNA_synthase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00458">
        <property type="entry name" value="aspS_nondisc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003483">
        <property type="entry name" value="PRK05159.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450:SF1">
        <property type="entry name" value="ASPARTATE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450">
        <property type="entry name" value="ASPARTYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="13">
        <location>
            <begin position="298"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="56"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG93282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="610" mass="72384" checksum="E66AECF2385DA2E9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQG6</accession>
    <name>A0A1J1GQG6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">cAMP-dependent protein kinase regulatory subunit, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00124200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cAMP-dependent kinase regulatory chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526357.1">
        <property type="nucleotide sequence ID" value="XM_028674758.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQG6"/>
    <dbReference type="GeneID" id="39729767"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00124200"/>
    <dbReference type="OMA" id="MEEKHYT"/>
    <dbReference type="OrthoDB" id="417078at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005952">
        <property type="term" value="C:cAMP-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030552">
        <property type="term" value="F:cAMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004862">
        <property type="term" value="F:cAMP-dependent protein kinase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034236">
        <property type="term" value="F:protein kinase A catalytic subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000006">
        <property type="entry name" value="cAMP-dependent protein kinase type I-alpha regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050503">
        <property type="entry name" value="cAMP-dep_PK_reg_su-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012198">
        <property type="entry name" value="cAMP_dep_PK_reg_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11635">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11635:SF152">
        <property type="entry name" value="CAMP-DEPENDENT PROTEIN KINASE TYPE I REGULATORY SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000548">
        <property type="entry name" value="PK_regulatory"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00103">
        <property type="entry name" value="CAMPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00888">
        <property type="entry name" value="CNMP_BINDING_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0114">cAMP</keyword>
    <keyword evidence="3 7" id="KW-0116">cAMP-binding</keyword>
    <keyword evidence="5 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="9">
        <location>
            <begin position="188"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="9">
        <location>
            <begin position="310"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="13"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="375"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="384"/>
        </location>
        <ligand>
            <name>3',5'-cyclic AMP</name>
            <dbReference type="ChEBI" id="CHEBI:58165"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000548-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG93535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="439" mass="50859" checksum="94855828FF18C2AE" modified="2017-02-15" version="1">MGNVCTWRQGKGKSADENLSIKKENGIQNDLEKNDKNVKNENKPMISENKRNINEEKDITLKESSIDKRENENDPKESERIDENVENKECSKLNKQVVITLNKNQIINEEYSSDGDETEYHSEMDKNEIEKKESDIANIEGRKNKRLSVSAEAYGEWNKKKENFVAKIYEKDEEEKLKIREALNESFLFNHLNEKEFETIVDAFFDKNVNEGMNIINEGDDGDLLYVIDEGEVEIYKNKGDKKEILTVLKSKDVFGELALLYNSKRAATATALTNCHLWALDRESFTYIIKDNVAKKRQMYEDILKQVTILQDMDPYERSKVADCLKSKNYTDEEIIIKEGEEGDTFYMLIDGNAIALKNDKIIKTYKKGDYFGELALLKNQPRAATVKCQKFCQVVYLDRKSFKRLLGPIEEILYRNVENYKDVLKQLGLDTTCIEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQM7</accession>
    <name>A0A1J1GQM7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00129800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526413.1">
        <property type="nucleotide sequence ID" value="XM_028674820.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQM7"/>
    <dbReference type="GeneID" id="39729823"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00129800"/>
    <dbReference type="OMA" id="RFLKGIW"/>
    <dbReference type="OrthoDB" id="332676at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012385035" evidence="2">
        <location>
            <begin position="20"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="504"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="504"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="514"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1067" mass="128859" checksum="C2CB5095EB6D738D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR09</accession>
    <name>A0A1J1GR09_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">60S ribosome subunit biogenesis protein NIP7 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00226100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts with pre-ribosome complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the NIP7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527679.1">
        <property type="nucleotide sequence ID" value="XM_028670981.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR09"/>
    <dbReference type="GeneID" id="39730788"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00226100"/>
    <dbReference type="OMA" id="LISMGTC"/>
    <dbReference type="OrthoDB" id="27490at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042255">
        <property type="term" value="P:ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21146">
        <property type="entry name" value="Nip7_N_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21151">
        <property type="entry name" value="PUA_Nip7-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.130.10:FF:000002">
        <property type="entry name" value="60S ribosome subunit biogenesis protein NIP7 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.220:FF:000001">
        <property type="entry name" value="60S ribosome subunit biogenesis protein NIP7 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="entry name" value="PUA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040598">
        <property type="entry name" value="NIP7_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055359">
        <property type="entry name" value="Nip7_N_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016686">
        <property type="entry name" value="Ribosomal_synth_fac_NIP7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005155">
        <property type="entry name" value="UPF0113_PUA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17833">
        <property type="entry name" value="pre-PUA_NIP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03657">
        <property type="entry name" value="UPF0113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017190">
        <property type="entry name" value="Rbsml_synth_fac_NIP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88802">
        <property type="entry name" value="Pre-PUA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50890">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="PUA" evidence="7">
        <location>
            <begin position="95"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR017190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="179" mass="20262" checksum="EAEC557B1B955898" modified="2017-02-15" version="1">MRPLNDQETMIVFKKLAKFVGNNLLSMLSYNNEEYVFRLHKSNVYFVRADVAKQAESINKKSLISLGICLGKFTKANNFFIKITSISFLNEFCIHKIWLKESGEKNFLFGNNVLKSHLLKVSDNIKKGDGIIVLSGNDNPIGFGISTRNTQEIKILNVTDTILIHQGDVGEYLRSESTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR13</accession>
    <name>A0A1J1GR13_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">SP-RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00210500</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NSE2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527523.1">
        <property type="nucleotide sequence ID" value="XM_028670807.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR13"/>
    <dbReference type="GeneID" id="39730632"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00210500"/>
    <dbReference type="OMA" id="VNRYVKF"/>
    <dbReference type="OrthoDB" id="26899at2759"/>
    <dbReference type="UniPathway" id="UPA00886"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030915">
        <property type="term" value="C:Smc5-Smc6 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061665">
        <property type="term" value="F:SUMO ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16651">
        <property type="entry name" value="SPL-RING_NSE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026846">
        <property type="entry name" value="Nse2(Mms21)"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004181">
        <property type="entry name" value="Znf_MIZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21330">
        <property type="entry name" value="E3 SUMO-PROTEIN LIGASE NSE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21330:SF1">
        <property type="entry name" value="E3 SUMO-PROTEIN LIGASE NSE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11789">
        <property type="entry name" value="zf-Nse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SP-RING-type" evidence="10">
        <location>
            <begin position="117"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF11789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG94708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="231" mass="27908" checksum="02AF94B7A8151A60" modified="2017-02-15" version="1">MQKKKDSVEKILKGNEDELTEQIPFFKDIWNDLDKFEEEYTPSNEIQKYHYNLQKSLYNILFSIKYFRSDEINIDTDFLKLVNKFVKLKLEGNQNDEKDIARLARFHLKHQKENDEDELLVDEEVGVFPSRCPISQMPFETPVTQRFSKNRKACVHTFEKSFIHKLMQNKDTIECPIAACKKKVYKNSLHPDYEYLHYSRYKKFRENITEAKEYFKNLRNEEENKSFDFVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR37</accession>
    <name>A0A1J1GR37_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RlmI-like PUA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00237400</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the methyltransferase superfamily. RlmI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527790.1">
        <property type="nucleotide sequence ID" value="XM_028671105.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR37"/>
    <dbReference type="GeneID" id="39730902"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00237400"/>
    <dbReference type="OMA" id="FKGIHKY"/>
    <dbReference type="OrthoDB" id="333664at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="entry name" value="PUA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.80">
        <property type="entry name" value="RNA methyltransferase domain (HRMD) like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041532">
        <property type="entry name" value="RlmI-like_PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42873">
        <property type="entry name" value="RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42873:SF1">
        <property type="entry name" value="S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17785">
        <property type="entry name" value="PUA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50890">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RlmI-like PUA" evidence="8">
        <location>
            <begin position="172"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="121"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="589" mass="69909" checksum="060CC27C2693B294" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR69</accession>
    <name>A0A1J1GR69_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00240600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527822.1">
        <property type="nucleotide sequence ID" value="XM_028671140.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730934"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00240600"/>
    <dbReference type="OMA" id="GIESWNW"/>
    <dbReference type="OrthoDB" id="385537at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="218"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="334" mass="39008" checksum="89F9442A31B2B55A" modified="2017-02-15" version="1">MSLKNQXXVNELNETLFNENYKIKGNTTEVELMETIENFSDDLVSNNDSIDSNQSVNISSKKANEKGNEKSKKDNFKCNRKKNISSSNRKTENSYSNIPQIYETYDSNVKDEFHSENSNEEQNEKNIFSNVLAILYIIIAIVIILHLYLNEDHVIIKNITILKLKFVGLIKRIPIFKNLMKTVTLTNKKINYFLDNITTKSDLMKPYMEALKQLNTEFSILFIILIITFFTATFILHIMYGLMTMKQEKDNSEKENVVLVTNKMTVEEYEDKSFTYSELAKLHEDKDYICLKNKRAGEGIESWNWQVRKFKNEKNDNNDNDICSDIELSDMDEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRC5</accession>
    <name>A0A1J1GRC5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00130100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526416.1">
        <property type="nucleotide sequence ID" value="XM_028674824.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729826"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00130100"/>
    <dbReference type="OMA" id="YREINYL"/>
    <dbReference type="OrthoDB" id="370850at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="628"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="752"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="785"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="815"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1339"/>
            <end position="1358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1396"/>
            <end position="1413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1448"/>
            <end position="1474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="433"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="443"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1511" mass="182149" checksum="E1614E848EC81E0B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRE6</accession>
    <name>A0A1J1GRE6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rhoptry protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00226300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527681.1">
        <property type="nucleotide sequence ID" value="XM_028670983.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730790"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00226300"/>
    <dbReference type="OMA" id="HICASHI"/>
    <dbReference type="OrthoDB" id="371899at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="779"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1703"/>
            <end position="1727"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="535"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1120"/>
            <end position="1248"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1290"/>
            <end position="1369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1749" mass="209444" checksum="AF4673080A318C12" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRE7</accession>
    <name>A0A1J1GRE7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">KIF-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00239100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527807.1">
        <property type="nucleotide sequence ID" value="XM_028671124.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRE7"/>
    <dbReference type="GeneID" id="39730919"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00239100"/>
    <dbReference type="OMA" id="EIYIIYL"/>
    <dbReference type="OrthoDB" id="392779at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="205"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="288"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="58"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="353"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1085" mass="132788" checksum="E4E0B1131A3B2572" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRH6</accession>
    <name>A0A1J1GRH6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00229600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527713.1">
        <property type="nucleotide sequence ID" value="XM_028671018.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730823"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00229600"/>
    <dbReference type="OMA" id="FHENVNI"/>
    <dbReference type="OrthoDB" id="10253476at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048487">
        <property type="term" value="F:beta-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007023">
        <property type="term" value="P:post-chaperonin tubulin folding pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007021">
        <property type="term" value="P:tubulin complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033162">
        <property type="entry name" value="TBCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12658">
        <property type="entry name" value="BETA-TUBULIN COFACTOR D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12658:SF0">
        <property type="entry name" value="TUBULIN-SPECIFIC CHAPERONE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23579">
        <property type="entry name" value="ARM_TBCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="2038"/>
            <end position="2057"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2192" mass="264459" checksum="68400F587B961CA7" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRT6</accession>
    <name>A0A1J1GRT6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00240900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527825.1">
        <property type="nucleotide sequence ID" value="XM_028671143.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRT6"/>
    <dbReference type="GeneID" id="39730937"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00240900"/>
    <dbReference type="OMA" id="EEWFEHF"/>
    <dbReference type="OrthoDB" id="369006at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="376" mass="45330" checksum="F262CD8E9380A56F" modified="2017-02-15" version="1">MDDEILKTLTDRELKKIILNEAKNILSQRKLTESEKDGILQKNKSFESFFNIENTEKSEGKSEYNERKPTTHEKNEYLENKNKNFFNLQDFSLKYSETCKINNLNYENIEYELIISFINTFNNELKYQLKLNNINKQEDKENNIIHKMVKIFMDKLIFYCTHPIIFLSQNNNNNSLFEKEIISHIENFFKQLEETNDKDILFKNCLNEILKNIFNFKPNLNWISRQAFVDLIKIIIEENIKRNELCVICTTDLIKKNFKNLDFFQVDNVVVLIEIVQYAIIFLVEKKYSMKNFSLKNEKWFEHFGDLLQLLKNSEWKIFLNQLIAIETFLYDKKRENIKKSFNELYKHKIEFASTKNSSYSRWFKIEMPLSINLFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS44</accession>
    <name>A0A1J1GS44_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Roadblock/LAMTOR2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00383200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GAMAD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526949.1">
        <property type="nucleotide sequence ID" value="XM_028670170.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS44"/>
    <dbReference type="GeneID" id="39732362"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00383200"/>
    <dbReference type="OMA" id="CLQSCRF"/>
    <dbReference type="OrthoDB" id="9985637at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.30:FF:000012">
        <property type="entry name" value="Dynein light chain 2B, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.30">
        <property type="entry name" value="Dynein light chain 2a, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004942">
        <property type="entry name" value="Roadblock/LAMTOR2_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10779">
        <property type="entry name" value="DYNEIN LIGHT CHAIN ROADBLOCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03259">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103196">
        <property type="entry name" value="Roadblock/LC7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Roadblock/LAMTOR2" evidence="2">
        <location>
            <begin position="21"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="109" mass="12409" checksum="FBA7AE943BDD7499" modified="2017-02-15" version="1">MAGSSSEISESLNGWMNNNSSIISYVLINSDGIPLKYNEEVSYEYAVKQASLFSDLITKTKKCVKELLPQENEFNSNLRIRTKKETEYILCNHGDYSLITQQNCKDTTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS62</accession>
    <name>A0A1J1GS62_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Deubiquitinating enzyme MINDY-3/4 conserved domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00159100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MINDY deubiquitinase family. FAM188 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526704.1">
        <property type="nucleotide sequence ID" value="XM_028675143.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS62"/>
    <dbReference type="GeneID" id="39730116"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00159100"/>
    <dbReference type="OMA" id="AFLLPEC"/>
    <dbReference type="OrthoDB" id="10263628at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990380">
        <property type="term" value="F:K48-linked deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071108">
        <property type="term" value="P:protein K48-linked deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025257">
        <property type="entry name" value="MINDY-3/4_CD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039785">
        <property type="entry name" value="MINY3/4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12473">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12473:SF8">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13898">
        <property type="entry name" value="MINDY-3_4_CD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01174">
        <property type="entry name" value="DUF4205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Deubiquitinating enzyme MINDY-3/4 conserved" evidence="3">
        <location>
            <begin position="222"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="137"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="313"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="358"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="323"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="358"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="385"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="395"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="417"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="874" mass="103493" checksum="DDBB1D543360322A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSA4</accession>
    <name>A0A1J1GSA4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sugar phosphate phosphatase</fullName>
            <ecNumber evidence="7">3.1.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00015600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>beta-D-fructose 1-phosphate + H2O = D-fructose + phosphate</text>
            <dbReference type="Rhea" id="RHEA:35603"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:37721"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:138881"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>beta-D-fructose 6-phosphate = dihydroxyacetone + D-glyceraldehyde 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:28002"/>
            <dbReference type="ChEBI" id="CHEBI:16016"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="7">
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </cofactor>
    </comment>
    <comment type="domain">
        <text evidence="7">Subfamily III proteins have a conserved RTxK motif about 40-50 residues from the C-terminus; the threonine may be replaced by serine or cysteine.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.-" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528198.1">
        <property type="nucleotide sequence ID" value="XM_028671558.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSA4"/>
    <dbReference type="GeneID" id="39728678"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00015600"/>
    <dbReference type="OMA" id="IFARQKM"/>
    <dbReference type="OrthoDB" id="541375at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097023">
        <property type="term" value="F:fructose 6-phosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103026">
        <property type="term" value="F:fructose-1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10880:FF:000007">
        <property type="entry name" value="DUF89 domain protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10880">
        <property type="entry name" value="Uncharacterised protein PF01937, DUF89, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036075">
        <property type="entry name" value="ARMT-1-like_metal-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039763">
        <property type="entry name" value="ARMT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002791">
        <property type="entry name" value="ARMT1-like_metal-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12260">
        <property type="entry name" value="DAMAGE-CONTROL PHOSPHATASE ARMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12260:SF6">
        <property type="entry name" value="DAMAGE-CONTROL PHOSPHATASE ARMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01937">
        <property type="entry name" value="ARMT1-like_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111321">
        <property type="entry name" value="AF1104-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Damage-control phosphatase ARMT1-like metal-binding" evidence="8">
        <location>
            <begin position="48"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG95387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="450" mass="54349" checksum="91B063F65473B2EB" modified="2017-02-15" version="1">MYFKAFYENFKDEFIYLRKEDDTLPDMLTCEKSNTMENDTIVRRIPGTILKRVEEQNIEYTKKNNIDIKLEKLRELFKNAHKHTYEMLKCDLDEKYWNFLLSYHIDKDIKIINNLWLFNEYYFYRYLNCAYDFENSNYDFFESEKNDAINCNKDIIEEICSCAKKLIEMYNKNPDKKIFSIFFFFSLWSNQFDLSWNPTKNKNEQHKSDEKDIKKKTLREKKFYFSTENIDKLYNSFFLENILCNDIDNIHKDITTQKRKRFDIVLDNMGVELITDFCLLYFLTNYFDEITIHVKKFPLFVSDTMTKDIHYSLNILCGDNKYPNTVFMANKWKQLIETKKWVIRDDIYWNIPLPYWIISKSLLEELKKSSFVCFKGDANYRRCLGDLNFDFSLPHKDVLNYFPLKVIALRCLKSPLGCGINKNIVEKLNKSSDDWSNYGEYAILQYYSPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSF4</accession>
    <name>A0A1J1GSF4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">YGGT family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00012500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528167.1">
        <property type="nucleotide sequence ID" value="XM_028671523.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSF4"/>
    <dbReference type="GeneID" id="39728647"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00012500"/>
    <dbReference type="OrthoDB" id="392195at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003425">
        <property type="entry name" value="CCB3/YggT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33219:SF14">
        <property type="entry name" value="PROTEIN COFACTOR ASSEMBLY OF COMPLEX C SUBUNIT B CCB3, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33219">
        <property type="entry name" value="YLMG HOMOLOG PROTEIN 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02325">
        <property type="entry name" value="CCB3_YggT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="192" mass="23259" checksum="88C425C5C1C93020" modified="2017-02-15" version="1">MLYFSFYIIHCIKKMYFFFSLLVFFLLNINIQSKNIDFLKFNAFVYPYKKHKVFTKHHNNCVYKNKNIQNIIQRNVFLKQNIKNIVRSKSILKLKLFSSSSVSIFKFFLSNKQNIKLAALHFIRIYKFIIYIRCLLEWLPQINPHLNPFVFIFTFTNNYVQFFHKIVPNVFGIDLSGIFSWLFLEMIENFLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSH4</accession>
    <name>A0A1J1GSH4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sel1 repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00020200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528244.1">
        <property type="nucleotide sequence ID" value="XM_028671608.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728724"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00020200"/>
    <dbReference type="OrthoDB" id="272077at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012181807" description="Sel1 repeat-containing protein" evidence="3">
        <location>
            <begin position="22"/>
            <end position="2025"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1157"/>
            <end position="1205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1222"/>
            <end position="1251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1312"/>
            <end position="1337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1664"/>
            <end position="1690"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="24"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="702"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1184"/>
            <end position="1203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1222"/>
            <end position="1237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1238"/>
            <end position="1251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1665"/>
            <end position="1676"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2025" mass="242501" checksum="FF271FA0180586EC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSN7</accession>
    <name>A0A1J1GSN7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DDH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00273800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528350.1">
        <property type="nucleotide sequence ID" value="XM_028671726.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSN7"/>
    <dbReference type="GeneID" id="39731270"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00273800"/>
    <dbReference type="OMA" id="TCKNESR"/>
    <dbReference type="OrthoDB" id="374045at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004309">
        <property type="term" value="F:exopolyphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.20">
        <property type="entry name" value="DHHA2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1640.10">
        <property type="entry name" value="inorganic pyrophosphatase (n-terminal core)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001667">
        <property type="entry name" value="DDH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038222">
        <property type="entry name" value="DHHA2_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12112">
        <property type="entry name" value="BNIP - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12112:SF39">
        <property type="entry name" value="EG:152A3.5 PROTEIN (FBGN0003116_PN PROTEIN)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01368">
        <property type="entry name" value="DHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="DHH phosphoesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDH" evidence="1">
        <location>
            <begin position="121"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="501" mass="60220" checksum="B2F014152B66B92A" modified="2017-02-15" version="1">MLNDNINDDHSNLFSYKEPEINEDINLFQSNQVPWFYHLIHILQLKKDDFINIKNFVENEKSRGNEYNHVLNIIDYKTYQDEILKINSNSKNTLSAYLYSCKYFLSQYSKNIESNKNVHFVFVFGNITADLDSVCSSIIYSFFLYIWFCLKKKAEKKKNIDEIKFFIPVINIKKNDIKLKILITWWLRKSEILSDEDVFVFQDDIHLLEVLKHNNKYDICLVDFNDFEVNNIYNINNVKSIIDHHMIKEGSENKRITKSIYPIYICSCMVIIAYLYKNSSEFLGIPFINKNMMWLIYGTILRDSNNFIREDFGKRWIQPDLNIFLSLKKFYKISNKMDIYLTYKYKSIRFSVDLRKFGIENLLFCDYKDYNYQVSQKKIKIRIASIDFSVDLLFSNENVNRLIKELYELCEENNFSIFIFIGSYFNHYKLNKDMGLFFYKNDVNKDDLLDTLLTNKDIKLSNKSFKNITYNNNSKTVDIFQINNQNYSRKKLEYLLYEFFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSR6</accession>
    <name>A0A1J1GSR6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rhoptry neck protein 6, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RON6</name>
        <name evidence="3" type="ORF">PGAL8A_00405600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527173.1">
        <property type="nucleotide sequence ID" value="XM_028670418.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSR6"/>
    <dbReference type="GeneID" id="39732586"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00405600"/>
    <dbReference type="OMA" id="QNCTIND"/>
    <dbReference type="OrthoDB" id="392870at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012588420" evidence="2">
        <location>
            <begin position="16"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="508"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="408"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="447"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="508"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="525"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="882" mass="104641" checksum="3ED7DF2F75F483A1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTJ9</accession>
    <name>A0A1J1GTJ9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribonuclease H2 subunit B wHTH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00306600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528662.1">
        <property type="nucleotide sequence ID" value="XM_028672072.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTJ9"/>
    <dbReference type="GeneID" id="39731599"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00306600"/>
    <dbReference type="OrthoDB" id="364759at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019024">
        <property type="entry name" value="RNase_H2_suB_wHTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09468">
        <property type="entry name" value="RNase_H2-Ydr279"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribonuclease H2 subunit B wHTH" evidence="1">
        <location>
            <begin position="107"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="343" mass="42002" checksum="4E7E1086FA160C32" modified="2017-02-15" version="1">MEDKNAFLFHIYNTEINENEREERNKIKNYSFIKLPSISEPSKNVLYHFNEETNELYLLERNYYNPKIETIRHEKDKINKNNISIFINNYALENAYSYYCYPIDAIFIFISIIYENCSHNKFITLENYLNNILNDNEKTKNEVIKNTLSIFKKNVNRIKDRLKIVCDELHENEMFYYKPNINKVKNFYNFKCIILFNYIIENQIIFPDYAQYMEKEILEKYKSDENRHPFNLIKEEKKQIDKYNQYKKYIDNYLIEFNKQHYKINGDNLRAFIWLVIKGFMCLSLEEKIIPDDINKKLNEIKEDEEEKRKTQNMIFTKNKKHPLQVPRNQPMIDSFFKRKKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTU6</accession>
    <name>A0A1J1GTU6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00314500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528740.1">
        <property type="nucleotide sequence ID" value="XM_028672159.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTU6"/>
    <dbReference type="GeneID" id="39731678"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00314500"/>
    <dbReference type="OMA" id="IFIHLTQ"/>
    <dbReference type="OrthoDB" id="4207594at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009618934" evidence="1">
        <location>
            <begin position="17"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="120" mass="14585" checksum="1EB70B3013BBCB71" modified="2017-02-15" version="1" fragment="single">MRLLKIFLIFIHLTQSFILKKLKWEEKTNKKKFQLFKTRYFRKWKSIPYIRDSGENHLKELTRERVRLSKHTVNPVTLGANFLFICNLDNRLSSKDVTHFFNYFIGNDNCVARIKKNRFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTX1</accession>
    <name>A0A1J1GTX1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00314300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528738.1">
        <property type="nucleotide sequence ID" value="XM_028672157.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTX1"/>
    <dbReference type="GeneID" id="39731676"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00314300"/>
    <dbReference type="OMA" id="EYKKEEH"/>
    <dbReference type="OrthoDB" id="373013at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="164"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="628"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="87"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="164"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="175"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="343"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="384"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="642"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="656"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="687"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="729"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="741"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="789"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="809"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="828"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="840"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="855"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="882"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="905"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="918"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="941"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="966"/>
            <end position="997"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1006" mass="119343" checksum="D56D76122C1C9E83" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU85</accession>
    <name>A0A1J1GU85_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ER membrane protein complex subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">EMC4</name>
        <name evidence="9" type="ORF">PGAL8A_00306900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EMC4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528665.1">
        <property type="nucleotide sequence ID" value="XM_028672075.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU85"/>
    <dbReference type="GeneID" id="39731602"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00306900"/>
    <dbReference type="OMA" id="MNIFVMF"/>
    <dbReference type="OrthoDB" id="369569at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009445">
        <property type="entry name" value="TMEM85/Emc4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19315">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06417">
        <property type="entry name" value="EMC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG95857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="189" mass="21975" checksum="A36726C3D6BC1857" modified="2017-02-15" version="1">MNRWDFNLRKYDQKCENLIEPFGYKFVNDAKNTYGYGDSYLKVEKSINNLNKLNKNDNKSNLSEENTKILNKMAWNICINSIKGLAMNLFVMFMSGGASGIFGIIFIIYSIYNILKSLFNINDVFKSVENNTKQKFWLQKICFIIVNCSVFIYIMNVCSKSGLLPIRSGDYFYYIPHKKIKQKGVGSFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUH9</accession>
    <name>A0A1J1GUH9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00210200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527520.1">
        <property type="nucleotide sequence ID" value="XM_028670804.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUH9"/>
    <dbReference type="GeneID" id="39730629"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00210200"/>
    <dbReference type="OMA" id="DYAQDEP"/>
    <dbReference type="OrthoDB" id="442317at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043001">
        <property type="term" value="P:Golgi to plasma membrane protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034067">
        <property type="term" value="P:protein localization to Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45909">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-RELATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45909:SF1">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR-RELATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="574"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="804"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="574"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="605"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="626"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="804"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="847"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="909"/>
            <end position="926"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1050" mass="126395" checksum="CB88C6B75D11FE42" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUQ9</accession>
    <name>A0A1J1GUQ9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Trimethylguanosine synthase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Cap-specific guanine-N(2) methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00319200</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78479"/>
            <dbReference type="Rhea" id="RHEA-COMP:19087"/>
            <dbReference type="Rhea" id="RHEA-COMP:19089"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:167623"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:78480"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78507"/>
            <dbReference type="Rhea" id="RHEA-COMP:19088"/>
            <dbReference type="Rhea" id="RHEA-COMP:19090"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:167623"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="3">
            <dbReference type="Rhea" id="RHEA:78508"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78471"/>
            <dbReference type="Rhea" id="RHEA-COMP:19085"/>
            <dbReference type="Rhea" id="RHEA-COMP:19087"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:78472"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78475"/>
            <dbReference type="Rhea" id="RHEA-COMP:19086"/>
            <dbReference type="Rhea" id="RHEA-COMP:19088"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:78476"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528787.1">
        <property type="nucleotide sequence ID" value="XM_028672213.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUQ9"/>
    <dbReference type="GeneID" id="39731725"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00319200"/>
    <dbReference type="OMA" id="KYETYIY"/>
    <dbReference type="OrthoDB" id="194443at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071164">
        <property type="term" value="F:RNA cap trimethylguanosine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019012">
        <property type="entry name" value="RNA_cap_Gua-N2-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14741">
        <property type="entry name" value="S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14741:SF32">
        <property type="entry name" value="TRIMETHYLGUANOSINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09445">
        <property type="entry name" value="Methyltransf_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="677"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="716"/>
            <end position="738"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00018517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG95979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="916" mass="111100" checksum="AAD5958967F12905" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUX1</accession>
    <name>A0A1J1GUX1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Zinc finger protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00223800</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the ZNF593/BUD20 C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527656.1">
        <property type="nucleotide sequence ID" value="XM_028670955.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUX1"/>
    <dbReference type="GeneID" id="39730765"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00223800"/>
    <dbReference type="OMA" id="GCGQFKC"/>
    <dbReference type="OrthoDB" id="24683at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:002771">
        <property type="entry name" value="Zinc finger protein 593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051879">
        <property type="entry name" value="C2H2-ZF_Maturation_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46095">
        <property type="entry name" value="ZINC FINGER PROTEIN 593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46095:SF1">
        <property type="entry name" value="ZINC FINGER PROTEIN 593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG94841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="104" mass="12534" checksum="62EA63577025A230" modified="2017-02-15" version="1">MVLSSRKKKNPRNTIKSKILKTRKRKRDFDEVYKDYFNKPDLPHDEDLKGCGQFKCFACDIYFINNDAMKQHEKTKKHKRRVKLLNKEKVYTYKDSLKAAEITF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV05</accession>
    <name>A0A1J1GV05_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00227000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527688.1">
        <property type="nucleotide sequence ID" value="XM_028670991.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV05"/>
    <dbReference type="GeneID" id="39730797"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00227000"/>
    <dbReference type="OMA" id="RENNDKM"/>
    <dbReference type="OrthoDB" id="372820at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="100"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="199"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="409"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="830"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="25"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="109"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="129"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="199"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="210"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="412"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="426"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="496"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1039" mass="123825" checksum="C9DB463E805E36CB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV65</accession>
    <name>A0A1J1GV65_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00366600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529246.1">
        <property type="nucleotide sequence ID" value="XM_028672722.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV65"/>
    <dbReference type="GeneID" id="39732196"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00366600"/>
    <dbReference type="OMA" id="MYDDYFT"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048026">
        <property type="term" value="P:positive regulation of mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052084">
        <property type="entry name" value="SF3B4_spliceosome_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48030">
        <property type="entry name" value="SPLICING FACTOR 3B SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48030:SF3">
        <property type="entry name" value="SPLICING FACTOR 3B SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="2">
        <location>
            <begin position="625"/>
            <end position="705"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1181" mass="139114" checksum="890E5C9F9229ED4C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV83</accession>
    <name>A0A1J1GV83_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00362900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529210.1">
        <property type="nucleotide sequence ID" value="XM_028672682.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV83"/>
    <dbReference type="GeneID" id="39732159"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00362900"/>
    <dbReference type="OMA" id="CSYEEYL"/>
    <dbReference type="OrthoDB" id="383050at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="266"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="299"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="372"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="407" mass="48156" checksum="B1A6618A8E66159A" modified="2017-02-15" version="1">MGYSTALINTVTHIKKSKIILFGFRILWITSIIAYMIILKVTSDHHLLVGQVEEELYKISNKQLLKDDKIFHNYNKSFNIINFICGSFLIFSCLVNILFSINIRIKNIKLSNYKKIVRIINLNLQVLIISLIFMENFDNQVFFCNLKEYLYWFQNYNNKINLFVNSGNNLCIMHKYANFFSLSFLIFSLIEFFTLYINTEKPFRKKFFIFYIKISTAFISLALFYFYLKNKYFFNNVLSKYNIFSLENFNESIKVIILSTQKQKTYYFQLLIFSTFFSGIFFLASGLYDLCSILKSCKFFLLVSVLISVCAFIIILSQLLFSTYILEESFFFCSYKEYVESNKNLEEKSLSTLGATSDITETNWFCNLKSFLFIYFVNIITGLIFFIVDFFVSVYLVFSKKYTAKYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVC4</accession>
    <name>A0A1J1GVC4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="16">ATP-dependent zinc metalloprotease FTSH, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PGAL8A_00346200</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the peptidase M41 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the N-terminal section; belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529049.1">
        <property type="nucleotide sequence ID" value="XM_028672503.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVC4"/>
    <dbReference type="GeneID" id="39731992"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00346200"/>
    <dbReference type="OMA" id="ANSGMDK"/>
    <dbReference type="OrthoDB" id="1413014at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005745">
        <property type="term" value="C:m-AAA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034982">
        <property type="term" value="P:mitochondrial protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19501">
        <property type="entry name" value="RecA-like_FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000019">
        <property type="entry name" value="AFG3-like AAA ATPase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.760:FF:000010">
        <property type="entry name" value="ATP-dependent zinc metalloprotease FTSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000001">
        <property type="entry name" value="ATP-dependent zinc metalloprotease FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1690.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="entry name" value="Peptidase M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01458">
        <property type="entry name" value="FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050928">
        <property type="entry name" value="ATP-dep_Zn_Metalloprotease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005936">
        <property type="entry name" value="FtsH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011546">
        <property type="entry name" value="Pept_M41_FtsH_extracell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01241">
        <property type="entry name" value="FtsH_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43655:SF2">
        <property type="entry name" value="AFG3 LIKE MATRIX AAA PEPTIDASE SUBUNIT 2, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43655">
        <property type="entry name" value="ATP-DEPENDENT PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06480">
        <property type="entry name" value="FtsH_ext"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="FtsH protease domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 16" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="247"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="15">
        <location>
            <begin position="444"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="896"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="896"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="953"/>
            <end position="975"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="CRG96244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="982" mass="113931" checksum="B52F5898A71BB755" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVF3</accession>
    <name>A0A1J1GVF3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RAP protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00350200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529089.1">
        <property type="nucleotide sequence ID" value="XM_028672548.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVF3"/>
    <dbReference type="GeneID" id="39732032"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00350200"/>
    <dbReference type="OMA" id="GPFIVDI"/>
    <dbReference type="OrthoDB" id="422904at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.960.10">
        <property type="entry name" value="VSR Endonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013584">
        <property type="entry name" value="RAP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08373">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00952">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51286">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RAP" evidence="2">
        <location>
            <begin position="622"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="499"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="501"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="699" mass="83515" checksum="C3313BA48B534054" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVF6</accession>
    <name>A0A1J1GVF6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Circumsporozoite protein</fullName>
            <shortName evidence="14">CS</shortName>
        </recommendedName>
        <component>
            <recommendedName>
                <fullName evidence="14">Circumsporozoite protein C-terminus</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="18" type="primary">CSP</name>
        <name evidence="18" type="ORF">PGAL8A_00003900</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 14">Essential sporozoite protein. In the mosquito vector, required for sporozoite development in the oocyst, migration through the vector hemolymph and entry into the vector salivary glands. In the vertebrate host, required for sporozoite migration through the host dermis and infection of host hepatocytes. Binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes.</text>
    </comment>
    <comment type="function">
        <molecule>Circumsporozoite protein C-terminus</molecule>
        <text evidence="14">In the vertebrate host, binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes and is required for sporozoite invasion of the host hepatocytes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Cell membrane</location>
            <topology evidence="14">Lipid-anchor</topology>
            <topology evidence="14">GPI-anchor</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 14">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="14">Localizes to the cytoplasm and the cell membrane in oocysts at day 6 post infection and then gradually distributes over the entire cell surface of the sporoblast and the budding sporozoites.</text>
    </comment>
    <comment type="domain">
        <text evidence="14">The GPI-anchor is essential for cell membrane localization and for sporozoite formation inside the oocyst.</text>
    </comment>
    <comment type="domain">
        <text evidence="14">The N-terminus is involved in the initial binding to heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes. The N-terminus masks the TSP type-1 (TSR) domain which maintains the sporozoites in a migratory state, enabling them to complete their journey to the salivary gland in the mosquito vector and then to the host liver. The unmasking of the TSP type-1 (TSR) domain when the sporozoite interacts with the host hepatocyte also protects sporozoites from host antibodies.</text>
    </comment>
    <comment type="domain">
        <text evidence="14">The TSP type-1 (TSR) domain is required for sporozoite development and invasion. CSP has two conformational states, an adhesive conformation in which the TSP type-1 (TSR) domain is exposed and a nonadhesive conformation in which the TSR is masked by the N-terminus. TSR-exposed conformation occurs during sporozoite development in the oocyst in the mosquito vector and during host hepatocyte invasion. TSR-masked conformation occurs during sporozoite migration through the hemolymph to salivary glands in the mosquito vector and in the host dermis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the plasmodium circumsporozoite protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528085.1">
        <property type="nucleotide sequence ID" value="XM_028671432.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVF6"/>
    <dbReference type="GeneID" id="39728561"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00003900"/>
    <dbReference type="OMA" id="GYSNTPN"/>
    <dbReference type="OrthoDB" id="5989160at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.100.10">
        <property type="entry name" value="Thrombospondin type-1 (TSP1) repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003067">
        <property type="entry name" value="Crcmsprzoite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000884">
        <property type="entry name" value="TSP1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036383">
        <property type="entry name" value="TSP1_rpt_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00090">
        <property type="entry name" value="TSP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01303">
        <property type="entry name" value="CRCMSPRZOITE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00209">
        <property type="entry name" value="TSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82895">
        <property type="entry name" value="TSP-1 type 1 repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 14" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 14" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11 14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 14" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="12 14" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="9 14 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="7 14 17" id="KW-0732">Signal</keyword>
    <keyword evidence="5 14" id="KW-0748">Sporozoite</keyword>
    <keyword evidence="16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012158948" description="Circumsporozoite protein" evidence="17">
        <location>
            <begin position="16"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="483"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="121"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="85"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="15">
        <location>
            <begin position="123"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="174"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="15">
        <location>
            <begin position="196"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="383"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="396"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="410"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU369056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="CRG95274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="505" mass="49263" checksum="9B413D968AD3A774" modified="2017-02-15" version="1">MKKLAILSASSFLFADFLFQEYQHNGNYKNFRLLNEVCYNNMNIQLYNELEMENYMSNTYFYNNKKTIRLLGENDNEANVNRANNNVANDNRANGNRGNVNRANDRNIPYFRENVVNLNQPVGGNGGVQPAGGNGGVQPAGGNGGVQPAGGNGGVQPAGGNGGAQPVAAGGGAQPVVADGGVQPLRQEGDAEEDGGNGGVQPAGGNGGVQPAGGNGGVQPAGGNGGVQPAGGNGGVQPAGGNGGVQPAGGNGGVQPAGGNGGVQPAGGNGGVQPAGGNGGVQPAGGNGGVQPAGGNGGAQPAGGNGGAQPAGGNGGAQPAGGNGGAQPAGGNGGAQPAGGNGGAQPAGGNGGAQPAGGNGGAQPAGGNGGAQPAGGNGGAQPAGGNDAAKPDGGNDDDKPEGGDEKSEEEKEDEPIPDPTQEEIDKYLKSILGNVTSEWTNCNVTCGKGIQAKIKSTSANKKREEITPNDVEVKICELERCSFSIFNVISNSLGLAIILTFLFFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVH4</accession>
    <name>A0A1J1GVH4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Regulator of chromosome condensation</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00371000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529290.1">
        <property type="nucleotide sequence ID" value="XM_028672771.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVH4"/>
    <dbReference type="GeneID" id="39732240"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00371000"/>
    <dbReference type="OMA" id="FRFNYHS"/>
    <dbReference type="OrthoDB" id="8068875at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051553">
        <property type="entry name" value="Ran_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982:SF1">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13540">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="839" mass="99963" checksum="E6FFA4C668253DF6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVI9</accession>
    <name>A0A1J1GVI9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fam-i protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00412500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000063">
        <property type="protein sequence ID" value="CRG96543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529348.1">
        <property type="nucleotide sequence ID" value="XM_028672835.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVI9"/>
    <dbReference type="GeneID" id="39732655"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00412500"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="74"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="138" mass="17147" checksum="CF77C04F571CE50A" modified="2017-02-15" version="1">MRVRLQKILNNCNKKMKDDLEKEMQEEKKKMEKDQEKLLKKKKEMEHWEKGVLRHKEEWERTLKEKQVFDESMLKVLEGRKKRITEEGEKWKKRMLIEKMELEKKIQKNKEEGEERMLKVIEKFEEKMLNEKKSGKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVS0</accession>
    <name>A0A1J1GVS0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ras-related protein Rab-11B, putative</fullName>
            <ecNumber evidence="2">3.6.5.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">RAB11b</name>
        <name evidence="2" type="ORF">PGAL8A_00251700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.2" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527928.1">
        <property type="nucleotide sequence ID" value="XM_028671258.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVS0"/>
    <dbReference type="GeneID" id="39731045"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00251700"/>
    <dbReference type="OMA" id="RVRAQIW"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003925">
        <property type="term" value="F:G protein activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001689">
        <property type="entry name" value="Ras-related protein Rab-11B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="229" mass="25814" checksum="7EBE37A11CAC7E5A" modified="2017-02-15" version="1">MSNEEYDHLYKIILVGDATVGKTHLLSRYIRGSLPSVSKATIGVEFATRTIPLAVGGTVKAQIWDTAGQERYRSITSAHYRRSAGAILVYDITKKKTFLSISKWLEEIRQNADKDIVIMLVGNKVDLTEQDESKRKVTYEQGANFAKENNLFFAETSAVSKLNVKHIFESLLQEIYNNRLKNNNGSFSNRSNATCESAIQLTKAQSVIKLNDKNENEIEEDNKNKVKCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVZ1</accession>
    <name>A0A1J1GVZ1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00430200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529526.1">
        <property type="nucleotide sequence ID" value="XM_028673033.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVZ1"/>
    <dbReference type="GeneID" id="39732834"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00430200"/>
    <dbReference type="OMA" id="ERRRNTW"/>
    <dbReference type="OrthoDB" id="328211at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="285"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="339" mass="40356" checksum="60A90AFBF70C0ED7" modified="2017-02-15" version="1">MDKKKSKKPGRIGKMINEFYINWNYRRHSWRASFYYNCLTTIAAFNIIFTLIFQQFIKSFNFFINYSCEYASINFMLTDLLIFLILTSFISILAFFLSRICSIFSNFTINDFMSLGKWIKRIGCTAKWFPWVLAILFVLWFIINLFNLITLYVTPSLWCKKRLNVTGTFVVNNCRIFEGKRTACTNIVAEQRGNANITYIRKCNDLNYLKNHNYFIFIPDFRKENYKQCNFNNLKVCIAYKDLRNDRFASEKAKAMKMEGCLENIPTNIEEFYDKDIQTSDLYKYAQIFTIGSNVTFFLLMFFFYFIKCTTQFDGLFYQSADNSEIFILQILRPLTPWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW13</accession>
    <name>A0A1J1GW13_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">P1 nuclease, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00420700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the nuclease type I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529431.1">
        <property type="nucleotide sequence ID" value="XM_028672927.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW13"/>
    <dbReference type="GeneID" id="39732739"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00420700"/>
    <dbReference type="OMA" id="HQPLRIA"/>
    <dbReference type="OrthoDB" id="441446at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11010">
        <property type="entry name" value="S1-P1_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.575.10">
        <property type="entry name" value="P1 Nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008947">
        <property type="entry name" value="PLipase_C/P1_nuclease_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003154">
        <property type="entry name" value="S1/P1nuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33146">
        <property type="entry name" value="ENDONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33146:SF26">
        <property type="entry name" value="ENDONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02265">
        <property type="entry name" value="S1-P1_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48537">
        <property type="entry name" value="Phospholipase C/P1 nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012181808" evidence="9">
        <location>
            <begin position="23"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="346"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG96627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="390" mass="45969" checksum="1E5135309AFD3DEA" modified="2017-02-15" version="1">MIIKRKWCINIIIFVISILCKNNKSFIKGFNNEGHEAIGMVAMSGLKSDQLYELKKLLNGKDLVDLGKWGHLVHDKIRGAEPMHFNLQNNDCKNISFSCDDKNGLCLINSIKYFYNKLLLPPNSNLNEDIKFKYPRNISFTDSDSLKYLVTLISDMHQPLRISFISDNGGKNINVTFFDNKLQKVKSNLFEYLENKIINKMIQKYQSSWYSGWTHVNRIFNDHKKDEDLFKKNGIDVIYIWAKDIVNDFCSEFYMNNSIESYMTLKEEKLYFDTTTELEISYELEYQLERLIRNNILRAGSRISILLNHIFAKKKFSNFRKRSEFDKVEYEELKKSKAASIYKNNALFINLAIIFVILLAIFYFNVLMNRRNKMRLPNKINEAELQEKCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWD0</accession>
    <name>A0A1J1GWD0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Leucine-rich repeat protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">LRR8</name>
        <name evidence="3" type="ORF">PGAL8A_00443000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529652.1">
        <property type="nucleotide sequence ID" value="XM_028673172.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWD0"/>
    <dbReference type="GeneID" id="39732963"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00443000"/>
    <dbReference type="OrthoDB" id="27917at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050576">
        <property type="entry name" value="Cilia_flagella_integrity"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45973:SF33">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_20, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45973">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14580">
        <property type="entry name" value="LRR_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52075">
        <property type="entry name" value="Outer arm dynein light chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="626" mass="75269" checksum="C3039A4CC7251DCF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWG4</accession>
    <name>A0A1J1GWG4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pre-mRNA polyadenylation factor Fip1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00447000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FIP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529692.1">
        <property type="nucleotide sequence ID" value="XM_028673217.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWG4"/>
    <dbReference type="GeneID" id="39733003"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00447000"/>
    <dbReference type="OMA" id="FEYINHN"/>
    <dbReference type="OrthoDB" id="1917198at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007854">
        <property type="entry name" value="Fip1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05182">
        <property type="entry name" value="Fip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pre-mRNA polyadenylation factor Fip1" evidence="5">
        <location>
            <begin position="83"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="289" mass="34807" checksum="F4CDB7D524FB5A56" modified="2017-02-15" version="1">MEDTDDEENVQVIVFGNSSKADFDDFYREEIIKEKNDEDKNNTNTNNSIKNEIQNEEIEDLDLDAQVLKATKENKVFMKYEYTNEKPWLYHNDISMWFNYNFDENSFKEWIQKHIDRRIEKHQNYQIENSDNIYNENFKNNINTSAYEDDLQISKNPNYKNQNIKNKMKYKNTKNNFYNNKNNILNNFNKDNSSIDDENYFDNDAYKNEDFYTYSNINKSNGSNKDIKNNFTQNYIYSNNNNASMNNYNNNNNNNINKLRDDTVDIPIQNDDLRQLQNLINFFKENPEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWI6</accession>
    <name>A0A1J1GWI6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">Uracil-DNA glycosylase</fullName>
            <shortName evidence="5">UDG</shortName>
            <ecNumber evidence="5 7">3.2.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00286600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 7">Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 7">
            <text>Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.</text>
            <dbReference type="EC" id="3.2.2.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 7">Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.27" evidence="5 7"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528477.1">
        <property type="nucleotide sequence ID" value="XM_028671868.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWI6"/>
    <dbReference type="GeneID" id="39731399"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00286600"/>
    <dbReference type="OrthoDB" id="10031947at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004844">
        <property type="term" value="F:uracil DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097510">
        <property type="term" value="P:base-excision repair, AP site formation via deaminated base removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10027">
        <property type="entry name" value="UDG-F1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="entry name" value="Uracil-DNA glycosylase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00148">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002043">
        <property type="entry name" value="UDG_fam1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018085">
        <property type="entry name" value="Ura-DNA_Glyclase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003588">
        <property type="entry name" value="PRK05254.1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003589">
        <property type="entry name" value="PRK05254.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003592">
        <property type="entry name" value="PRK05254.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00628">
        <property type="entry name" value="ung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11264">
        <property type="entry name" value="URACIL-DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11264:SF0">
        <property type="entry name" value="URACIL-DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00987">
        <property type="entry name" value="UreE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="Uracil-DNA glycosylase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00130">
        <property type="entry name" value="U_DNA_GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4 5 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uracil-DNA glycosylase-like" evidence="8">
        <location>
            <begin position="146"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5 6">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG95669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="314" mass="36846" checksum="31FA343BD9286B78" modified="2017-02-15" version="1">MNKVKVQKTIDYFFKSKRQKITNTKAEENANKCVESIGSSCLENSEINENDCKKRKIMNKDELENTKNIYDNNLNMIRKTENEIKNNEKASDYIEEIRKLMDIEWFKELQDELKKSYFKNMYLKIKEERKIKVIYPPEQLVFNAFLKTPLSKIKVVIVGQDPYHQKNQAMGLSFSVPFGIKIPPSLKNILKEIKQKSNHGNLISWSEQGVFLLNTSLTVEENKPASHKNYGWETFTDKVINIINQKKEKIIFMLWGNFAIKKCSKIDTTKHFILKAGHPSPLSIRHFENCDHFNKCNKILIENNLVPIKWELPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWP8</accession>
    <name>A0A1J1GWP8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Protein disulfide isomerase, putative</fullName>
            <ecNumber evidence="4">5.3.4.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">PDI9</name>
        <name evidence="4" type="ORF">PGAL8A_00432200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein disulfide isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.4.1" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529545.1">
        <property type="nucleotide sequence ID" value="XM_028673053.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWP8"/>
    <dbReference type="GeneID" id="39732854"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00432200"/>
    <dbReference type="OMA" id="ALFCNNK"/>
    <dbReference type="OrthoDB" id="72053at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034976">
        <property type="term" value="P:response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18929">
        <property type="entry name" value="PROTEIN DISULFIDE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18929:SF243">
        <property type="entry name" value="PROTEIN DISULFIDE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="397"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="510" mass="60651" checksum="0F45118428444CFF" modified="2017-02-15" version="1">MVVKLNYSFYLFFLYFFYIKFQFIQCVTDDGISEEETKNIKHLTHEVELQIYSQHSENVIALFCNNKELKCKNAYKEFIEASNELVDNEIVFVYVDTLTLPKTADNFEIKNVPKILTFRDFDPEKGYTFSKKYTKENIIEWFKLLPLPSIEVMDKTNVDKYVELQKKKGYASIIAFAIKNSDNAHKFVHFGETHKIPNLSVGLAYVEKEEETKIEIFNGPGSTIPNDLIRYKDVYIPDNNIWVSDKIYKFTKDYMDQFPIIINYSRKIIRPINNDIYFYIFSNLGDYSESLYAELYNVIKNYPEIKFVFPKSEEKSELFQLEHDMNLVCILDYRNASFDAVYQLLRPKKFIKEIDGDIKSEIVKNFIEDFYNNKITQYRKSQKPIKRREQQHYQIICTNNFESFVFDPERIVLIFYHVQGCKECKPILSFWESVSNYFHLENKYKNVLVATMDAKLNDMIDETVEFFPTLAIYPKGEDKLKRRKVFLFPVKLDTLIDIVDEMLEDIEEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWZ8</accession>
    <name>A0A1J1GWZ8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00465400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAM133 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529876.1">
        <property type="nucleotide sequence ID" value="XM_028673423.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWZ8"/>
    <dbReference type="GeneID" id="39733187"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00465400"/>
    <dbReference type="OMA" id="RPTWDDL"/>
    <dbReference type="OrthoDB" id="341593at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026766">
        <property type="entry name" value="Fam133"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31911:SF1">
        <property type="entry name" value="FAMILY WITH SEQUENCE SIMILARITY 133 MEMBER B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31911">
        <property type="entry name" value="PROTEIN FAM133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="89"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="111"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="165" mass="20064" checksum="EE89974E61F78452" modified="2017-02-15" version="1">MPKQRGFRPQGLIAPIQRIKYNGPTLLDKINRETRPTWDDLKDRIKNQEGNKMLEEYENAKYIEELNKNREEKIKEQEKRYIKKLKKEYKKKYKKKSDDNSTDSSDDDISKKRKRKRKKKKKKDRYSHSLSSDTTSNYSDKKKHKKQKKNDDINPFKLSNFFKMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX05</accession>
    <name>A0A1J1GX05_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00466200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529884.1">
        <property type="nucleotide sequence ID" value="XM_028673431.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX05"/>
    <dbReference type="GeneID" id="39733195"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00466200"/>
    <dbReference type="OMA" id="CTFYAEH"/>
    <dbReference type="OrthoDB" id="378536at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="431"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="476"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="500"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="101"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="500"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="539"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="560" mass="68631" checksum="3556508FADC72578" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX10</accession>
    <name>A0A1J1GX10_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine/threonine protein phosphatase CPPED1, putative</fullName>
            <ecNumber evidence="2">3.1.3.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">CPPED1</name>
        <name evidence="2" type="ORF">PGAL8A_00275700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528368.1">
        <property type="nucleotide sequence ID" value="XM_028671746.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX10"/>
    <dbReference type="GeneID" id="39731289"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00275700"/>
    <dbReference type="OMA" id="NEPTHET"/>
    <dbReference type="OrthoDB" id="45007at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051918">
        <property type="entry name" value="STPP_CPPED1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43143">
        <property type="entry name" value="METALLOPHOSPHOESTERASE, CALCINEURIN SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43143:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE CPPED1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="1">
        <location>
            <begin position="27"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="298" mass="35133" checksum="157D32480FAB80BF" modified="2017-02-15" version="1">MVLIKVQNNQGKSINENSFSPFYFILYGDIQYGMLRSDIGWFEERILLKKAIEKTNKLKPPFVIAMGDLSNANPSTEAQNEQYNDLKEDFKLLNKSIDLYVFCGNHDVGNSPTCETIKKYEDVWGDGYYSFIYNNCGFIILNSSILYDDTYVKSLRDKQLEWLEETLKKMQSLNLKYKFIFMHHPLMYDNIDEDENIGLIYVDKIRLYVDKNRFHIKKETRLIIYELMKKYNVNHIFCAHLHFNKEGNIDSNIKQIVISAVGMQVRDDKSGILIVQVNEKNVDYKYYPFDYIPNMISN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX25</accession>
    <name>A0A1J1GX25_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00469600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529918.1">
        <property type="nucleotide sequence ID" value="XM_028673469.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX25"/>
    <dbReference type="GeneID" id="39733229"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00469600"/>
    <dbReference type="OMA" id="VLNDYTN"/>
    <dbReference type="OrthoDB" id="375586at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="89" mass="10651" checksum="9D0FA4B6519A97E5" modified="2017-02-15" version="1">MNIKVFKNFLRVLKIEEKNGLDKNVLKELKNWGKEKLLKNDEILNEYLIYKNVLNDYTKILQENKAENKECKIEKIANYVGLTTNYTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXB5</accession>
    <name>A0A1J1GXB5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00451400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529737.1">
        <property type="nucleotide sequence ID" value="XM_028673267.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXB5"/>
    <dbReference type="GeneID" id="39733047"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00451400"/>
    <dbReference type="OMA" id="RVSNLWV"/>
    <dbReference type="OrthoDB" id="372693at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="638" mass="77532" checksum="CF9EA8CA381D18F3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXF8</accession>
    <name>A0A1J1GXF8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00472100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529943.1">
        <property type="nucleotide sequence ID" value="XM_028673496.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXF8"/>
    <dbReference type="GeneID" id="39733254"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00472100"/>
    <dbReference type="OMA" id="YRPCDFF"/>
    <dbReference type="OrthoDB" id="375351at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="133" mass="15231" checksum="A801AEA179C8C762" modified="2017-02-15" version="1">MGKKSDNSSQNNSNSSEKTRSTKLETQNSCDKKNSEISCEKNRHILKYKKGHNKNNNKINNYSKKIFSSINYIFCILGIICAWGAIDSLVDVISGKQVYISLICYSVVLLVAFVFLTLYICFIDRNYKPHELF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXG9</accession>
    <name>A0A1J1GXG9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Enoyl-CoA hydratase-related protein, putative</fullName>
            <ecNumber evidence="4">4.2.1.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00476200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.17" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529986.1">
        <property type="nucleotide sequence ID" value="XM_028673545.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXG9"/>
    <dbReference type="GeneID" id="39733295"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00476200"/>
    <dbReference type="OMA" id="EIIHDHF"/>
    <dbReference type="OrthoDB" id="16820at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004300">
        <property type="term" value="F:enoyl-CoA hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045004">
        <property type="entry name" value="ECH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052377">
        <property type="entry name" value="Mitochondrial_ECH-domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43602">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43602:SF1">
        <property type="entry name" value="ENOYL-COA HYDRATASE DOMAIN-CONTAINING PROTEIN 3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16113">
        <property type="entry name" value="ECH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl-CoA hydratase/isomerase" evidence="3">
        <location>
            <begin position="87"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="528" mass="63162" checksum="D13F65392FBB00EA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXI7</accession>
    <name>A0A1J1GXI7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">U3 small nucleolar ribonucleoprotein protein MPP10, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MPP10</name>
        <name evidence="8" type="ORF">PGAL8A_00486300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MPP10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530086.1">
        <property type="nucleotide sequence ID" value="XM_028673656.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXI7"/>
    <dbReference type="GeneID" id="39733396"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00486300"/>
    <dbReference type="OMA" id="HFAEDFG"/>
    <dbReference type="OrthoDB" id="445326at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034457">
        <property type="term" value="C:Mpp10 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005732">
        <property type="term" value="C:sno(s)RNA-containing ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012173">
        <property type="entry name" value="Mpp10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17039">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17039:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04006">
        <property type="entry name" value="Mpp10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="101"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="249"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="481"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="641"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="117"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="249"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="265"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="664"/>
            <end position="674"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="748" mass="90240" checksum="B0CBD8982F7C023D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYA3</accession>
    <name>A0A1J1GYA3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA-directed RNA polymerase II, putative</fullName>
            <ecNumber evidence="8">2.7.7.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00486600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530089.1">
        <property type="nucleotide sequence ID" value="XM_028673659.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYA3"/>
    <dbReference type="GeneID" id="39733399"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00486600"/>
    <dbReference type="OMA" id="ITCMASI"/>
    <dbReference type="OrthoDB" id="1162399at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003727">
        <property type="term" value="F:single-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031369">
        <property type="term" value="F:translation initiation factor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060213">
        <property type="term" value="P:positive regulation of nuclear-transcribed mRNA poly(A) tail shortening"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045948">
        <property type="term" value="P:positive regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04329">
        <property type="entry name" value="RNAP_II_Rpb7_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04462">
        <property type="entry name" value="S1_RNAPII_Rpb7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000043">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.120:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase II subunit RPB7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.120">
        <property type="entry name" value="RNA polymerase Rpb7-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036898">
        <property type="entry name" value="RNA_pol_Rpb7-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045113">
        <property type="entry name" value="Rpb7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005576">
        <property type="entry name" value="Rpb7-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709:SF4">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II, III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03876">
        <property type="entry name" value="SHS2_Rpb7-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88798">
        <property type="entry name" value="N-terminal, heterodimerisation domain of RBP7 (RpoE)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNA polymerase Rpb7-like N-terminal" evidence="7">
        <location>
            <begin position="9"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="6">
        <location>
            <begin position="78"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="177" mass="20225" checksum="516AEAF1ECC01630" modified="2017-02-15" version="1">MYFVIEEWKNVTIKPSQLGPRYQQCIEDMLRNSVEGQCNAKYGYIICVIRIIHNEPGRVQDGTGMIVVRVKYQAIVFKPFKDEVLDAIVTDVNKLGFFAQAGPLKIFISRTAIPKCFEYTEDAHYPSFSSGDYNIKPQTAVRIKLQGIRYDLSNMFAIATINNEYLGCIEYSSLQVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYE3</accession>
    <name>A0A1J1GYE3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Small nuclear ribonucleoprotein Sm D1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">snRNP core protein D1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00352200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the snRNP core protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529109.1">
        <property type="nucleotide sequence ID" value="XM_028672570.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYE3"/>
    <dbReference type="GeneID" id="39732052"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00352200"/>
    <dbReference type="OMA" id="TFLMKLT"/>
    <dbReference type="OrthoDB" id="9626941at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01724">
        <property type="entry name" value="Sm_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000050">
        <property type="entry name" value="Small nuclear ribonucleoprotein Sm D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027141">
        <property type="entry name" value="LSm4/Sm_D1/D3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034102">
        <property type="entry name" value="Sm_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23338">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="3 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 8" id="KW-0687">Ribonucleoprotein</keyword>
    <feature type="domain" description="Sm" evidence="7">
        <location>
            <begin position="2"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="96"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="96"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="113"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="123" mass="14026" checksum="032CCA87B6C62BFC" modified="2017-02-15" version="1">MKLVSFLMKLTNENVTIELKNGTLITGVITGVDIKMNTHMKNVKVVIKHKNIGEYNVNNKQFLSLEHVTIRGNNIRYFILSDSLPLDTLLVDDTPKQKVSKDKSFSNKERNKGKGRGRKISKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYJ6</accession>
    <name>A0A1J1GYJ6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S acidic ribosomal protein P1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPP1</name>
        <name evidence="5" type="ORF">PGAL8A_00330400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein P1/P2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528896.1">
        <property type="nucleotide sequence ID" value="XM_028672334.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYJ6"/>
    <dbReference type="GeneID" id="39731834"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00330400"/>
    <dbReference type="OMA" id="REELMCV"/>
    <dbReference type="OrthoDB" id="2194681at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030295">
        <property type="term" value="F:protein kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043021">
        <property type="term" value="F:ribonucleoprotein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05831">
        <property type="entry name" value="Ribosomal_P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1410:FF:000002">
        <property type="entry name" value="60S acidic ribosomal protein P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038716">
        <property type="entry name" value="P1/P2_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45696">
        <property type="entry name" value="60S ACIDIC RIBOSOMAL PROTEIN P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45696:SF10">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00428">
        <property type="entry name" value="Ribosomal_60s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="75"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="75"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="89"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="103"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="118" mass="13177" checksum="0C1CD1A4C5519DD5" modified="2017-02-15" version="1">MASIPVSELAECEKQELLCTYAALILFEEKMSITSDNIIKLIKKSNNSVLPYLPMLFEKTLKGKDIESLLSNLSLGGAPSTSVQATTEKPSEEKKETKKEEKVEEEEEEDDLGFSLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYX3</accession>
    <name>A0A1J1GYX3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA-editing substrate-binding complex 6 protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00535600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530579.1">
        <property type="nucleotide sequence ID" value="XM_028674203.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYX3"/>
    <dbReference type="GeneID" id="39733889"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00535600"/>
    <dbReference type="OMA" id="YEEKMHF"/>
    <dbReference type="OrthoDB" id="430737at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035770">
        <property type="term" value="C:ribonucleoprotein granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000963">
        <property type="term" value="P:mitochondrial RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044528">
        <property type="term" value="P:regulation of mitochondrial mRNA stability"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050870">
        <property type="entry name" value="FAST_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058917">
        <property type="entry name" value="RESC6_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21228">
        <property type="entry name" value="FAST LEU-RICH DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21228:SF40">
        <property type="entry name" value="LD45607P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26188">
        <property type="entry name" value="RESC6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA-editing substrate-binding complex 6 protein" evidence="2">
        <location>
            <begin position="64"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="RNA-editing substrate-binding complex 6 protein" evidence="2">
        <location>
            <begin position="155"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="500"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="790" mass="93632" checksum="9F0B53D7FA042563" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ05</accession>
    <name>A0A1J1GZ05_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-i protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00411800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000061">
        <property type="protein sequence ID" value="CRG96536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529341.1">
        <property type="nucleotide sequence ID" value="XM_028672827.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ05"/>
    <dbReference type="GeneID" id="39732648"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00411800"/>
    <dbReference type="OMA" id="YEENCIM"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="403" mass="49439" checksum="0B29B9B507BCD919" modified="2017-02-15" version="1">MDLNLSDAISTASNDSLSEGYSTAGFAHSPIKDAVVSIPKNSLYDNLNLSNAIQNPSEDINLDSAKSINLLHKKSLSIFQLVMIIISFLRFARAYSPKLKAKHKERVKLQNKWDNRDKKMKGDWEKMEKKWDERKEKENREKEELNKKEEERKKKTNNEMKKFNIRWNGEKDIENEKKRIETLYRQVVQLDEKWKKYEENCIMMNERKKEERKILEEKRRERREKHEEKMLKENEEWKKSMIEKNKEWKMSMIEKNKEWEKRMLKEKEGMGNGVLKEMEELEKKKLKKMEELDKKMKKKKEELEKRMIKKKEELEKKLLKEKKGKKEKEEEENRMQKEKEEWEKEMQKEKEEWEKGMQKEKEEWGKSIKEKNEKWEKEENMKVDEEESEFNLKWKKEFDKIKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ36</accession>
    <name>A0A1J1GZ36_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Dolichol-phosphate mannosyltransferase subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">DPM3</name>
        <name evidence="8" type="ORF">PGAL8A_00414850</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the dolichol-phosphate mannose (DPM) synthase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DPM3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529373.1">
        <property type="nucleotide sequence ID" value="XM_028672862.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ36"/>
    <dbReference type="GeneID" id="39732679"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00414850"/>
    <dbReference type="OMA" id="STILWIY"/>
    <dbReference type="OrthoDB" id="2014333at2759"/>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013174">
        <property type="entry name" value="DPM3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08285">
        <property type="entry name" value="DPM3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="35"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="90" mass="10682" checksum="A783529F2E33E66D" modified="2017-02-15" version="1">MLTRGKVIVLIFLFSTIIWINVYDKYKNSNSLIKWIYIPLYLITILAIYAIICISINLYNFNNIPNGHEELLKELSHIKNELEKKNFTFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZI9</accession>
    <name>A0A1J1GZI9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ATPase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00521700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530442.1">
        <property type="nucleotide sequence ID" value="XM_028674050.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZI9"/>
    <dbReference type="GeneID" id="39733750"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00521700"/>
    <dbReference type="OMA" id="NNLIYEF"/>
    <dbReference type="OrthoDB" id="370857at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990275">
        <property type="term" value="F:preribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000567">
        <property type="entry name" value="ATPase, AAA family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF171">
        <property type="entry name" value="NUCLEAR VALOSIN-CONTAINING PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="258"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="6">
        <location>
            <begin position="662"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="113"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1119" mass="130825" checksum="7F940CC6DCF7739A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZQ1</accession>
    <name>A0A1J1GZQ1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Pre-mRNA-splicing factor, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00038800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530750.1">
        <property type="nucleotide sequence ID" value="XM_028674392.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZQ1"/>
    <dbReference type="GeneID" id="39728912"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00038800"/>
    <dbReference type="OMA" id="PREPAYP"/>
    <dbReference type="OrthoDB" id="1099063at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12338">
        <property type="entry name" value="RRM1_SRSF1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000413">
        <property type="entry name" value="Serine/arginine-rich splicing factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000623">
        <property type="entry name" value="Splicing factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003:SF62">
        <property type="entry name" value="SERINE_ARGININE (SR)-TYPE SHUTTLING MRNA BINDING PROTEIN NPL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="8"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="111"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="175"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="198"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="245"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="271"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG97951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="300" mass="34589" checksum="591CAC48F9422FEB" modified="2017-02-15" version="1">MVIRDSVSRIYVGNLPSHVSSRDVENEFRKYGNIIKCDVKKTVSGAAFAFIEFEDARDAADAIKEKDGCEFEGNKLRVEVPFNARENGRYNSRGGGRGMMNRGPKSRRGRYVVEVTGLPTSGSWQDLKDHLRDAGECGHADVFKDGTGEVSFFNKADMLEAIDKFNGSIFRSHEGEKSKITIRQKKTSWRHDDGGYGRYSSRNRSYSSRSYSRSGNRSYTRSRSYSSRSYSRSRSRSSSSRSRSRSMDRRRDAYDKKRSYSRSLSYQERRRNNRSLSRSKSRSRSRTDSRSSSWSHKRRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZQ2</accession>
    <name>A0A1J1GZQ2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ras-related protein Rab-6, putative</fullName>
            <ecNumber evidence="6">3.6.5.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">RAB6</name>
        <name evidence="6" type="ORF">PGAL8A_00372400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.2" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529304.1">
        <property type="nucleotide sequence ID" value="XM_028672786.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZQ2"/>
    <dbReference type="GeneID" id="39732254"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00372400"/>
    <dbReference type="OMA" id="PVSNDGC"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003925">
        <property type="term" value="F:G protein activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01861">
        <property type="entry name" value="Rab6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000970">
        <property type="entry name" value="Ras-related protein Rab-6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050227">
        <property type="entry name" value="Rab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47977">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0636">Prenylation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="208" mass="23682" checksum="D03EB82A4D596EB5" modified="2017-02-15" version="1">MMDEFQNSGLNKYKLVFLGEQAVGKTSIITRFMYDTFDNNYQSTIGIDFLSKTLYLDEGPVRLQLWDTAGQERFRSLIPSYIRDSAAAIVVYDITNRQSFENTTKWIQDILNERGQDVIIALVGNKTDLGELRKVTYEEGLQKAQEYNTMFHETSAKAGHNIKVLFKKIASKLPNLENTNTNEANVVDIQLTNNSAQNEKSMLSKCLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZR3</accession>
    <name>A0A1J1GZR3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lysophospholipase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00049900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530861.1">
        <property type="nucleotide sequence ID" value="XM_028674516.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZR3"/>
    <dbReference type="GeneID" id="39729024"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00049900"/>
    <dbReference type="OMA" id="HGQSDGW"/>
    <dbReference type="OrthoDB" id="2498029at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051044">
        <property type="entry name" value="MAG_DAG_Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006494">
        <property type="entry name" value="PST_A"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01607">
        <property type="entry name" value="PST-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11614">
        <property type="entry name" value="PHOSPHOLIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="2">
        <location>
            <begin position="89"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="359" mass="41038" checksum="AEA81EB769EFA582" modified="2017-02-15" version="1">MAEGESSSKVKKKSTLDGNPKVDSFRNRDGLLLKTYAWLVQNPIGILILVHGMNSHIQFEYLKPNVEVVSNKEAKLIDGENFYLYQGSWIEQFNKNNFSVYGLDLQGHGQSEAWRGLRSNIKRYDDLVYDVLQFINRVHDMLSLSNKKDNSATLHENINSPNIPPIYIMGFSMGGNIVLRILEILGKSKDNSKVKISGCISLAGMVSIEHLKQKKSYKYFYIPMSKLASNLIPNARITPSLEFEKYPFVNDVMAFDKLKCDKPITCRFGYELLRAVDTLHEDMEHIDENIPLLFIHSKEDSACHYEGVVEFCNKLKNSKKELFTVENMDHMLTMEPGNEAILQKIIEWLTQISKELGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZX1</accession>
    <name>A0A1J1GZX1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fam-b protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00027500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530640.1">
        <property type="nucleotide sequence ID" value="XM_028674270.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZX1"/>
    <dbReference type="GeneID" id="39728798"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00027500"/>
    <dbReference type="OMA" id="RKENKAM"/>
    <dbReference type="OrthoDB" id="371349at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009618951" description="Fam-b protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="113" mass="13523" checksum="23C2491CEF3F4941" modified="2017-02-15" version="1">MTRLTYFCLSFFFFFLLTKVTNSFEFDPGNISHNQFSFTEINVNKLKIADPPYTVFNFATEVVNTHDIIENELQKKEKKAMRRFKYDLDEKIDRSNKILNKILKDSKAFFEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZX6</accession>
    <name>A0A1J1GZX6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00532300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530546.1">
        <property type="nucleotide sequence ID" value="XM_028674166.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZX6"/>
    <dbReference type="GeneID" id="39733856"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00532300"/>
    <dbReference type="OrthoDB" id="378626at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="438" mass="52504" checksum="A91CC668A9DD8E4E" modified="2017-02-15" version="1">MKFVFFQKSRKMYKNIKDNTENKIDEKDEKVIIRLKRKVEETTIPSIYVKKSNKRICNGIFYKHIDTIFPEEDTDKKNVDCINLFLKYEQLNCNAYTQFLEKKRKFNSLKNYEKDLKGTINSLKKFKIVNQNIQYVNLDGEKKGTFKIIDIDLHKNINDNIESVEKEKNKEGKYMKEQDYEYDLYILDNEKLQLDNYMDYLYNIKNNNVDPSEVVVLEDIYGSNSEEYEMYSYTSSFDSNSKKEMSDYPDESSCNRNDTSECSDYFDENIYNDDYDKNENIYNDDYDKNENIYNDDYDKNVNSDDRDQNMNNDNHDYITYSDNFNDSNCSDDYNESINSDKCNMNVSDNGEQGNFRNIESYIHKNNPLEYNIYKHNFKKKNENKISTYNIKMNSLSFEEKIKDELKKRLKKKNGNLLNVALSDKLKILEQMENEYYNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZZ6</accession>
    <name>A0A1J1GZZ6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cysteine-rich secretory protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00045900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530825.1">
        <property type="nucleotide sequence ID" value="XM_028674476.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZZ6"/>
    <dbReference type="GeneID" id="39728984"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00045900"/>
    <dbReference type="OMA" id="TWYEGIN"/>
    <dbReference type="OrthoDB" id="337038at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05380">
        <property type="entry name" value="CAP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00837">
        <property type="entry name" value="V5TPXLIKE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="2">
        <location>
            <begin position="28"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="196" mass="23131" checksum="1B5B09D46235A5D7" modified="2017-02-15" version="1">MITFFLFNIFCFLFICFYIIVEGKSCKFNKNLIIEKHNDFRLKHNAKPIYWNKKLENASQKEANLIKTNSDCILTSKQINTNYFNFFVNNEIELAVNSWYEGINDYDFELGVIKRNNNVFEFTQILWKTVENIGCSTACCKTTGIFICKYDNYPNRPGYFSDNVGTIDTTFVFDDLIVEKETNTNFSIYNKNTFYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H198</accession>
    <name>A0A1J1H198_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00488600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530109.1">
        <property type="nucleotide sequence ID" value="XM_028673681.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H198"/>
    <dbReference type="GeneID" id="39733419"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00488600"/>
    <dbReference type="OMA" id="REKNHIT"/>
    <dbReference type="OrthoDB" id="270651at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="646" mass="77441" checksum="535D69BDFC2F7BA5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1R8</accession>
    <name>A0A1J1H1R8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cyanocobalamin reductase (cyanide-eliminating)</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00484100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530064.1">
        <property type="nucleotide sequence ID" value="XM_028673630.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1R8"/>
    <dbReference type="GeneID" id="39733374"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00484100"/>
    <dbReference type="OMA" id="HKYGGWF"/>
    <dbReference type="OrthoDB" id="376656at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48147:SF3">
        <property type="entry name" value="MYELIN TRANSCRIPTION FACTOR 1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48147">
        <property type="entry name" value="PROTEIN CBG23787"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1073"/>
            <end position="1094"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="59"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="114"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="980"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="811"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="64"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="114"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="153"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="229"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="980"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1002"/>
            <end position="1014"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1134" mass="133365" checksum="07B3FC729011CAEF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3M0</accession>
    <name>A0A1J1H3M0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tyrosine--tRNA ligase</fullName>
            <ecNumber evidence="4">6.1.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Tyrosyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PGAL8A_00052200</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>tRNA(Tyr) + L-tyrosine + ATP = L-tyrosyl-tRNA(Tyr) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10220"/>
            <dbReference type="Rhea" id="RHEA-COMP:9706"/>
            <dbReference type="Rhea" id="RHEA-COMP:9707"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78536"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.1" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530884.1">
        <property type="nucleotide sequence ID" value="XM_028674542.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3M0"/>
    <dbReference type="GeneID" id="39729047"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00052200"/>
    <dbReference type="OMA" id="RKIHMLA"/>
    <dbReference type="OrthoDB" id="197206at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004831">
        <property type="term" value="F:tyrosine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006437">
        <property type="term" value="P:tyrosyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000085">
        <property type="entry name" value="Tyrosine--tRNA ligase 1 cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000103">
        <property type="entry name" value="tyrosine--tRNA ligase 1, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023617">
        <property type="entry name" value="Tyr-tRNA-ligase_arc/euk-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050489">
        <property type="entry name" value="Tyr-tRNA_synthase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006330">
        <property type="entry name" value="PRK08560.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46264:SF4">
        <property type="entry name" value="TYROSINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46264">
        <property type="entry name" value="TYROSINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006588">
        <property type="entry name" value="TyrRS_arch_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 13 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG98087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="372" mass="43727" checksum="12C93E59A1AED17F" modified="2017-02-15" version="1">MEKNIIKREENEVEERNEEIDNIENIDKRFNEIISISCECIQPEELKTKLLLKRRLICYDGFEPSGRMHIAQGLLKCLIVNKLTSNGCKFIFWIADWFAQLNNKMSGDLKKIRKMGNYFIEVWKSCGMNMENVEFLWASDEINKKPNDYWSLVIDISRSFNINRIKRCLKIMGRSEGEDNYCSQILYPCMQCADIFFLNVDICQLGIDQRKVNMLAREYCDIKKMKKKPIILSHEMLPGLLEGQEKMSKSDENSAIFMDDLEADVNRKIKKAYCPPNIIENNPIFSYAKSIIYPYYNKFHLVRKEKNGGDKIYYDIKELENDYISGLVHPLDLKDNVAIYINKLLQPVRDHFQNNAEAKKLLSEIKKYKVTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3V8</accession>
    <name>A0A1J1H3V8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribosomal protein L37</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">RPL37</name>
        <name evidence="10" type="ORF">PGAL8A_00046500</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the eukaryotic ribosomal protein eL37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530831.1">
        <property type="nucleotide sequence ID" value="XM_028674483.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3V8"/>
    <dbReference type="GeneID" id="39728990"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00046500"/>
    <dbReference type="OMA" id="RMAYLKH"/>
    <dbReference type="OrthoDB" id="10259236at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.30:FF:000001">
        <property type="entry name" value="Ribosomal protein L37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001569">
        <property type="entry name" value="Ribosomal_eL37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011331">
        <property type="entry name" value="Ribosomal_eL37/eL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018267">
        <property type="entry name" value="Ribosomal_eL37_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10768">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10768:SF0">
        <property type="entry name" value="RIBOSOMAL PROTEIN L37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01907">
        <property type="entry name" value="Ribosomal_L37e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01077">
        <property type="entry name" value="RIBOSOMAL_L37E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7 9 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 9" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG98034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="92" mass="10511" checksum="399A003C590FBA9F" modified="2017-02-15" version="1">MGKAGKGTGSFGKRNGKSHFLCIRCGKRSYHLQKKKCASCGYPSAKKRRFNWSVKAKRRNTTGTGRCRYIKTLRRKLKNNFTEGSTPKPKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2012-05-16" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>H7CDY6</accession>
    <name>H7CDY6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Open reading frame 129</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ORF129</name>
        <name evidence="2" type="ORF">PGAL8A_API03400</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <geneLocation type="apicoplast" evidence="1"/>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2012" name="Mol. Biol. Evol." volume="29" first="2095" last="2099">
            <title>The Plasmodium Apicoplast Genome: Conserved Structure and Close Relationship of P. ovale to Rodent Malaria Parasites.</title>
            <authorList>
                <person name="Arisue N."/>
                <person name="Hashimoto T."/>
                <person name="Mitsui H."/>
                <person name="Palacpac N.M.Q."/>
                <person name="Kaneko A."/>
                <person name="Kawai S."/>
                <person name="Hasegawa M."/>
                <person name="Tanabe K."/>
                <person name="Horii T."/>
            </authorList>
            <dbReference type="PubMed" id="22396524"/>
            <dbReference type="DOI" id="10.1093/molbev/mss082"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">A8</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">8A</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AB649424">
        <property type="protein sequence ID" value="BAL70756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LN835293">
        <property type="protein sequence ID" value="CRG98245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009325472.1">
        <property type="nucleotide sequence ID" value="NC_031963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="H7CDY6"/>
    <dbReference type="GeneID" id="30315773"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_API03400"/>
    <dbReference type="OMA" id="ILYKCKF"/>
    <dbReference type="OrthoDB" id="392886at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Apicoplast API"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0933">Apicoplast</keyword>
    <keyword evidence="1" id="KW-0934">Plastid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAL70756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="118" mass="14591" checksum="02FA187469F809EC" modified="2012-05-16" version="1">MAIIYKCKFLIKNIKTNLNPILNLKFKLYNININFLNKLITEYLNNYNINIFIIYIYSNKTFKIIYNYTIFNLYKKFLKIINKIILIYKILLYKKNQLLFYNIYQLLNIIYNNIKNYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2012-05-16" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>H7CDZ4</accession>
    <name>H7CDZ4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Open reading frame 51</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ORF51</name>
        <name evidence="2" type="ORF">PGAL8A_API04500</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <geneLocation type="apicoplast" evidence="1"/>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2012" name="Mol. Biol. Evol." volume="29" first="2095" last="2099">
            <title>The Plasmodium Apicoplast Genome: Conserved Structure and Close Relationship of P. ovale to Rodent Malaria Parasites.</title>
            <authorList>
                <person name="Arisue N."/>
                <person name="Hashimoto T."/>
                <person name="Mitsui H."/>
                <person name="Palacpac N.M.Q."/>
                <person name="Kaneko A."/>
                <person name="Kawai S."/>
                <person name="Hasegawa M."/>
                <person name="Tanabe K."/>
                <person name="Horii T."/>
            </authorList>
            <dbReference type="PubMed" id="22396524"/>
            <dbReference type="DOI" id="10.1093/molbev/mss082"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">A8</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">8A</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AB649424">
        <property type="protein sequence ID" value="BAL70764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LN835293">
        <property type="protein sequence ID" value="CRG98255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009325482.1">
        <property type="nucleotide sequence ID" value="NC_031963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="H7CDZ4"/>
    <dbReference type="GeneID" id="30315788"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_API04500"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Apicoplast API"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0933">Apicoplast</keyword>
    <keyword evidence="1" id="KW-0934">Plastid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAL70764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="47" mass="5985" checksum="14C8933681B54D89" modified="2012-05-16" version="1">MNTFNKNLYINKYKKLLKYYKNNIKIKYILYRKNILILKKLRYLNII</sequence>
</entry>
<entry dataset="TrEMBL" created="2012-07-11" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>I2FKB9</accession>
    <name>I2FKB9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Glucose-6-phosphate isomerase</fullName>
            <ecNumber evidence="3 8">5.3.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">GPI</name>
        <name evidence="10" type="ORF">PGAL8A_00307500</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2012" name="Gene" volume="502" first="36" last="39">
            <title>Age of the last common ancestor of extant Plasmodium parasite lineages.</title>
            <authorList>
                <person name="Hayakawa T."/>
                <person name="Tachibana S."/>
                <person name="Hikosaka K."/>
                <person name="Arisue N."/>
                <person name="Matsui A."/>
                <person name="Horii T."/>
                <person name="Tanabe K."/>
            </authorList>
            <dbReference type="PubMed" id="22555021"/>
            <dbReference type="DOI" id="10.1016/j.gene.2012.04.037"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11816"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="EC" id="5.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the GPI family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.9" evidence="3 8"/>
    <dbReference type="EMBL" id="AB571128">
        <property type="protein sequence ID" value="BAM15604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="I2FKB9"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00307500"/>
    <dbReference type="OMA" id="DWYRQLW"/>
    <dbReference type="OrthoDB" id="5831190at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00181"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004347">
        <property type="term" value="F:glucose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048029">
        <property type="term" value="F:monosaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051156">
        <property type="term" value="P:glucose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05015">
        <property type="entry name" value="SIS_PGI_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05016">
        <property type="entry name" value="SIS_PGI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00473">
        <property type="entry name" value="G6P_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001672">
        <property type="entry name" value="G6P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023096">
        <property type="entry name" value="G6P_Isomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018189">
        <property type="entry name" value="Phosphoglucose_isomerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035476">
        <property type="entry name" value="SIS_PGI_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035482">
        <property type="entry name" value="SIS_PGI_2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001211">
        <property type="entry name" value="PRK00179.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469:SF1">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00342">
        <property type="entry name" value="PGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00662">
        <property type="entry name" value="G6PISOMERASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SIS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00765">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00174">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51463">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="5 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6 8 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAM15604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG95863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="575" mass="66741" checksum="300E2139AACBC2BB" modified="2012-07-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL48</accession>
    <name>A0A1J1GL48_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-actin-capping protein subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">CPalpha</name>
        <name evidence="4" type="ORF">PGAL8A_00075800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterodimer of an alpha and a beta subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the F-actin-capping protein alpha subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525874.1">
        <property type="nucleotide sequence ID" value="XM_028675200.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL48"/>
    <dbReference type="GeneID" id="39729283"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00075800"/>
    <dbReference type="OMA" id="KSEWTFA"/>
    <dbReference type="OrthoDB" id="340550at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030863">
        <property type="term" value="C:cortical cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008290">
        <property type="term" value="C:F-actin capping protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030036">
        <property type="term" value="P:actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051016">
        <property type="term" value="P:barbed-end actin filament capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.60">
        <property type="entry name" value="F-actin capping protein, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.210">
        <property type="entry name" value="F-actin capping protein, beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002189">
        <property type="entry name" value="CapZ_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037282">
        <property type="entry name" value="CapZ_alpha/beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042276">
        <property type="entry name" value="CapZ_alpha/beta_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042489">
        <property type="entry name" value="CapZ_alpha_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10653">
        <property type="entry name" value="F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10653:SF0">
        <property type="entry name" value="F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01267">
        <property type="entry name" value="F-actin_cap_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90096">
        <property type="entry name" value="Subunits of heterodimeric actin filament capping protein Capz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0117">Actin capping</keyword>
    <keyword evidence="2 3" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU365077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="302" mass="35568" checksum="F608D7B68F444E7C" modified="2017-02-15" version="1">MEKLLNEKKKFIRHVILNAPPGKIYDLVSDLKVLFGSNQFILNSIKEAILNYNENNYALIPVGENDYIITCEQSKIDNSYIHPKLKLLVNVNHMKRKVTSMSELKELNYSNELENYRKICYEKLEKYIQLHYLKWNEIQTINFPTVNINSKNGLIVKCNSSVYACEKEQKFNLSFIICCDRHYLKNFYTSSWRSSWNVNFLPTDEEILLNGTIDIALTYFEDASINFKTTKTFEKKVQDIEKFASNILSAIGECENYTLYDLNNFLINTNKELIKNIRKIIPLNGEKFDWRNTHQDIPIQIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL91</accession>
    <name>A0A1J1GL91_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00088000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525998.1">
        <property type="nucleotide sequence ID" value="XM_028671333.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL91"/>
    <dbReference type="GeneID" id="39729404"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00088000"/>
    <dbReference type="OMA" id="EWYKGKA"/>
    <dbReference type="OrthoDB" id="364608at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00821">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="2">
        <location>
            <begin position="158"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="238" mass="27411" checksum="6833D023AC2900BA" modified="2017-02-15" version="1">MGNTVPYSCYERWGKRTPDGPLINYNPQIPNNGSMAILLENFEYELNEETNDTTKNNNLSINRKDENNNENINKNNINLNVIRSARRRPTYSPTARKVIIETEDEDDDKLSTDGSDENISAKDIKDEKIQQYRKTLTKVVKIKTAIFHETVKVTCSKDGKMLEWYKGKADGDGKKKPIGSFPLNKITSIRTKADNLKSLEIAVSSVQISTYLFIFKTREEREDWQNNLESFKKVMSMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLI6</accession>
    <name>A0A1J1GLI6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">LETM1-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00090800</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526026.1">
        <property type="nucleotide sequence ID" value="XM_028671644.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLI6"/>
    <dbReference type="GeneID" id="39729432"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00090800"/>
    <dbReference type="OMA" id="ICKDRGM"/>
    <dbReference type="OrthoDB" id="275278at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030003">
        <property type="term" value="P:intracellular monoatomic cation homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033122">
        <property type="entry name" value="LETM1-like_RBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044202">
        <property type="entry name" value="LETM1/MDM38-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14009">
        <property type="entry name" value="LEUCINE ZIPPER-EF-HAND CONTAINING TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14009:SF1">
        <property type="entry name" value="MITOCHONDRIAL PROTON_CALCIUM EXCHANGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07766">
        <property type="entry name" value="LETM1_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51758">
        <property type="entry name" value="LETM1_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="341"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="Letm1 RBD" evidence="11">
        <location>
            <begin position="383"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="166"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="582"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="129"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="140"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="167"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG93204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="729" mass="86536" checksum="03B13C91FFEE0DCF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLV9</accession>
    <name>A0A1J1GLV9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00107400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526191.1">
        <property type="nucleotide sequence ID" value="XM_028673477.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLV9"/>
    <dbReference type="GeneID" id="39729600"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00107400"/>
    <dbReference type="OrthoDB" id="390912at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="116" mass="14323" checksum="A83AF716A646B6DC" modified="2017-02-15" version="1">MILKRNKTLNDFPYHLCWFGLKPNLKFLIDTNFKFSCLEEFYLFRFSNITSFNLLNLNHSNNNFVNVWFDNLDNLIKCFKIKYSSNKSKIYLYEKYFNKKYPVNDIFNYKKPEQFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM02</accession>
    <name>A0A1J1GM02_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Actin-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ALP3</name>
        <name evidence="4" type="ORF">PGAL8A_00096700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526083.1">
        <property type="nucleotide sequence ID" value="XM_028672277.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM02"/>
    <dbReference type="GeneID" id="39729491"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00096700"/>
    <dbReference type="OrthoDB" id="337660at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="79"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="504" mass="60218" checksum="BFE6EE24D840BD84" modified="2017-02-15" version="1">MEKKLKKNDNENDYKHIILQIGRKYTYVGFSGLHKPLSVINTPDIFVYNEKFHNSNEDNEIYEIIEVFSKTKKKENDKNNDEKLLQLNDKKEKEKSKKKNEINDDDRDEEKKIKKETKKKEKNLIYHYEYKYSQDLNLWNIFFEEYLFKIFHNLIKTNIKTKKVIVVLNMFIPTIIKYALCKSLIVNSENSSISYINDLISPLYLCNCNTCLVVDLGYLNCRLLPVMNGLPLYHYCTYINNGGFYINKEIKRLLKEQYIKRDTFKNENLHKKIDNIINDECNSNKDVFNNNDLKNDSKYIKEEMKDESDDFLNYYWNLYTQEEIINVIDSLSDNDIENIKIKYFYLKNDKNNFFSNKYILFQYKKYEIIIEPETRWKACEILFHKNYDQNLYSLFSNILEKLNIMETSVFHNILLVGGCSNIKGIISKIAEVVFQVLKEKNKLAGNFENKVNFLFPKISPNLRQFIGASIYSNLENLPEYTEEHINNNVLYDHLNEDVYMTFKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMM7</accession>
    <name>A0A1J1GMM7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Mitochondrial inner membrane protein OXA1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">OXA1</name>
        <name evidence="8" type="ORF">PGAL8A_00121600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the OXA1/ALB3/YidC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526331.1">
        <property type="nucleotide sequence ID" value="XM_028674729.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMM7"/>
    <dbReference type="GeneID" id="39729741"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00121600"/>
    <dbReference type="OMA" id="LNCTKIM"/>
    <dbReference type="OrthoDB" id="264532at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032977">
        <property type="term" value="F:membrane insertase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032979">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane from matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20069">
        <property type="entry name" value="5TM_Oxa1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001708">
        <property type="entry name" value="YidC/ALB3/OXA1/COX18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028055">
        <property type="entry name" value="YidC/Oxa/ALB_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428:SF65">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX18, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428">
        <property type="entry name" value="OXA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02096">
        <property type="entry name" value="60KD_IMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="266"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="319"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="373"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="Membrane insertase YidC/Oxa/ALB C-terminal" evidence="7">
        <location>
            <begin position="193"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="453" mass="54106" checksum="DC0B7CE69D97C6D8" modified="2017-02-15" version="1">MIFTYLQNNLQNSQLKKNSLNLFINSICLKNKRYIIINRNYKNIICKNLKNDNYSSLMFFRNFSIFTNFINNKYPKQNESKIRENFTNYPEHMNKNENKYDEDKKEKSYEFLENENNLLVEKNKLDNNSLLNDKKKLEGTEEEYYNNDSFTHFIIEKCKNNARNDEDIYEDTWYVRLIYELLNCTKIILDCSWMTSIIATTIFMRIIILPLTISAERDRRKQKILNPLIKDLTNKLKINAQDGNIKKALEYKKRILNIRNTHGISLIPKSIILMTFFQTPLFCIFYFSMKKMSSYPDIFKDFTFESPLWLDSLSLPDPYYILPFLSSLLLLSNNELTSLIDKNINNNNQNKLYLEESEFQKNIRKATKIGMRLFYISSVFFFKSMPSGLFIYFITNTFFQLFITQICKVKFVERFLDLPPLHSKGFSFDNDDNHNNLKKNNIHMDDLLKNKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMV7</accession>
    <name>A0A1J1GMV7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00149000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526606.1">
        <property type="nucleotide sequence ID" value="XM_028675035.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMV7"/>
    <dbReference type="GeneID" id="39730014"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00149000"/>
    <dbReference type="OMA" id="FIANWFF"/>
    <dbReference type="OrthoDB" id="376917at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="151"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="46"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="290" mass="34478" checksum="588B4B8FB6DAA517" modified="2017-02-15" version="1">MKSRTFDNLFASFLNISSSSGDSIDSSSEKCSSEISVSSLSTENLFDNENINPSKTNSQRKSSIAYDEEKETSNSDLEYEITSKYVKSILKNKEKKKFYEFKKYLSDTDVFSTFVQIFLHLIKNKEEIKNPYDYIINFFKLKNNDYDNEKKKVLIEENKFYKKENEELNNKINLLEVEIYDIQKKNCCNTIVKIFFKDDDEQFNASDIFNKIIKNNKKFKIEPSFIFTKDIFFLFLNFLNDATRTKLHDILIQKTCEQNHSFFYDKLLKKLMKFINYYLSFDKSSINEHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMY1</accession>
    <name>A0A1J1GMY1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcription factor with AP2 domain(S), putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ApiAP2</name>
        <name evidence="3" type="ORF">PGAL8A_00132600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526443.1">
        <property type="nucleotide sequence ID" value="XM_028674853.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729851"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00132600"/>
    <dbReference type="OrthoDB" id="385798at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053300">
        <property type="entry name" value="Homeobox-like_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45795">
        <property type="entry name" value="EARLY GAMETOCYTE ENRICHED PHOSPHOPROTEIN EGXP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45795:SF1">
        <property type="entry name" value="MACRO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="42"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="708"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="821"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1638"/>
            <end position="1665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="53"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="273"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="711"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="731"/>
            <end position="747"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1939" mass="227187" checksum="B41C3AF7FE1BF1FD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN02</accession>
    <name>A0A1J1GN02_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Polypyrimidine tract binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00135000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526467.1">
        <property type="nucleotide sequence ID" value="XM_028674880.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN02"/>
    <dbReference type="GeneID" id="39729875"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00135000"/>
    <dbReference type="OMA" id="CYNIPKD"/>
    <dbReference type="OrthoDB" id="296632at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12422">
        <property type="entry name" value="RRM2_PTBP1_hnRNPL_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021790">
        <property type="entry name" value="PTBP1-like_RRM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15592">
        <property type="entry name" value="MATRIN 3/NUCLEAR PROTEIN 220-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13893">
        <property type="entry name" value="RRM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11835">
        <property type="entry name" value="RRM_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="558"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="60"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="258"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="60"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="272"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="638" mass="74460" checksum="C7A86C14FC75A05F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN09</accession>
    <name>A0A1J1GN09_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Uroporphyrinogen decarboxylase</fullName>
            <ecNumber evidence="3 7">4.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">UROD</name>
        <name evidence="11" type="ORF">PGAL8A_00135800</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>uroporphyrinogen III + 4 H(+) = coproporphyrinogen III + 4 CO2</text>
            <dbReference type="Rhea" id="RHEA:19865"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57308"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="EC" id="4.1.1.37"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the uroporphyrinogen decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.37" evidence="3 7"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526475.1">
        <property type="nucleotide sequence ID" value="XM_028674888.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN09"/>
    <dbReference type="GeneID" id="39729883"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00135800"/>
    <dbReference type="OMA" id="LWLMRQA"/>
    <dbReference type="OrthoDB" id="339900at2759"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00321"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004853">
        <property type="term" value="F:uroporphyrinogen decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00717">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006361">
        <property type="entry name" value="Uroporphyrinogen_deCO2ase_HemE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000257">
        <property type="entry name" value="Uroporphyrinogen_deCOase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01464">
        <property type="entry name" value="hemE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21091">
        <property type="entry name" value="METHYLTETRAHYDROFOLATE:HOMOCYSTEINE METHYLTRANSFERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21091:SF169">
        <property type="entry name" value="UROPORPHYRINOGEN DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01208">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="UROD/MetE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00906">
        <property type="entry name" value="UROD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5 7 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 7" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009618920" description="Uroporphyrinogen decarboxylase" evidence="9">
        <location>
            <begin position="19"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="Uroporphyrinogen decarboxylase (URO-D)" evidence="10">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG93653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="412" mass="48976" checksum="6D755311B9C0BA7F" modified="2017-02-15" version="1">MFKNFLLILFLLFNETFCYINIRKINLKIFKIYRKLQMTNVDEVYCRPQSLKYKTYGRPKNDLVLRVIENKNENKFFEKIPIWIMRQAGRYLPEYLEYRKKYDFFEICKKAELSSEVTIMPYKRFSIDMLVIFSDILIIFNAMGLEIEFIEKVGPIFNKKITSYEDFEKLNLNIPEIIDNLHYVYDAINLTKKKIDNSVPILGFAGSPFTLFTYLTKNNKKTYEDSLKLIYEKPEDTHKILNKLSDICANHLINQIDSGANIIQIFDSNAEVVDKNIFKEFSVKYLEKVINLIKKHRPQCYIILFIKDNFHECIKNLMIDVLSITHKQLSEKSSEFYYKLFQNQIILQGALDPHILLLDDNKLIKNYTKKMIDKIFYKNKYIANLGHGILPNSKIDNVHTFINTINEYELQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN56</accession>
    <name>A0A1J1GN56_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Leucine-rich repeat protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00140700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526523.1">
        <property type="nucleotide sequence ID" value="XM_028674942.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729931"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00140700"/>
    <dbReference type="OMA" id="GDDNNHY"/>
    <dbReference type="OrthoDB" id="271226at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45617:SF165">
        <property type="entry name" value="COMMON DPR-INTERACTING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45617">
        <property type="entry name" value="LEUCINE RICH REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="353"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="411"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1506"/>
            <end position="1546"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="1708"/>
            <end position="1773"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="1940"/>
            <end position="2022"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="353"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="369"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="411"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="438"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="461"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="471"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="483"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="574"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="585"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="597"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="671"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="825"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1518"/>
            <end position="1537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2077" mass="248612" checksum="8B20BB4090B793C6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNA4</accession>
    <name>A0A1J1GNA4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">pyridoxal kinase</fullName>
            <ecNumber evidence="2">2.7.1.35</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PDXK</name>
        <name evidence="8" type="ORF">PGAL8A_00144700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pyridoxine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.35" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526563.1">
        <property type="nucleotide sequence ID" value="XM_028674986.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNA4"/>
    <dbReference type="GeneID" id="39729971"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00144700"/>
    <dbReference type="OMA" id="FLWICDP"/>
    <dbReference type="OrthoDB" id="3689at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008478">
        <property type="term" value="F:pyridoxal kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009443">
        <property type="term" value="P:pyridoxal 5'-phosphate salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01173">
        <property type="entry name" value="pyridoxal_pyridoxamine_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013749">
        <property type="entry name" value="PM/HMP-P_kinase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004625">
        <property type="entry name" value="PyrdxlKinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10534">
        <property type="entry name" value="PYRIDOXAL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10534:SF2">
        <property type="entry name" value="PYRIDOXAL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08543">
        <property type="entry name" value="Phos_pyr_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyridoxamine kinase/Phosphomethylpyrimidine kinase" evidence="7">
        <location>
            <begin position="121"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="312" mass="35923" checksum="E4083BA44638DA48" modified="2017-02-15" version="1">MNKENIISIQSQVFDGFCGNNVAIFVLRRRGHIPKILNTVQYYSKFKHIGVEIKSEELKTILNEFNESIQNVDNNIYFLTGYIRSKECVETVINNIIELKKKKKAICSNEKILKKDNYLIENLIDENFFWICDPVMGDNGKLYVDNGVVNTYKNFISFADIITPNQYELELLCNTKISDENDVINSIKSLLFKGVKIVIVTSINYIFDKDNLYLYIGFLNNKNKPVCFKYKFLRFDFNICGTGDLFSSLLLSFITRQKGNILLIISQVLNILQNVIKNSLNSLELLIIENQDIIASNGLNGTMIKEEEVFIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GND1</accession>
    <name>A0A1J1GND1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00168400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526798.1">
        <property type="nucleotide sequence ID" value="XM_028670003.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GND1"/>
    <dbReference type="GeneID" id="39730211"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00168400"/>
    <dbReference type="OMA" id="YYPTSEM"/>
    <dbReference type="OrthoDB" id="389832at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="199" mass="23704" checksum="0CECBD5D29153E23" modified="2017-02-15" version="1">MAISRSKIRHLFANATLQSYYPNSDMFKIPKVGNAPRLYNGLDPRKVHNYPWVNMFKTRTKKETGYQYGNWAGPSIHAMTPDELVTFFNNKDYLKHFTYKQILKATVGQFQFLFLLVGSLVVTVLPIFIFTMYIQKFEPLEVTMDPDEYYKHFHWHYYGGEIDHHAFSQYLEARRAVRYRNADINPVDWIPPEYRNEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNK3</accession>
    <name>A0A1J1GNK3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Checkpoint protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00157000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526683.1">
        <property type="nucleotide sequence ID" value="XM_028675120.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNK3"/>
    <dbReference type="GeneID" id="39730095"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00157000"/>
    <dbReference type="OMA" id="CRNNKDD"/>
    <dbReference type="OrthoDB" id="369002at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.70.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="298" mass="34893" checksum="CB4F72B3F26AE9D2" modified="2017-02-15" version="1">MKLHAEFKQDSIDDFLHVLKGLKEFSSYAIENSFLCFKFSEKYLYIFGNEKKHVEIFITITMNDLFYENFILKSNSNNEIIILVYIFQIYDIFKNISKNTKITIDLFEKNGICILLFKHHCNVTDAFKKYECGIEIINPSITKFPNIKMNKHSLCVNCKLKKCCKILNTYSKFHSDIIELNFQVNNKNCDIIFLMDSITIKNITTLKNNYVLKNILDKKNISESKEDSKNDLKKVIYIKTLTKALNILNECRNNKDDIGIFKITVPYNKCWFALKLGQFESSGNWKVVIVITDLNLNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNL6</accession>
    <name>A0A1J1GNL6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PIR-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00178300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000021">
        <property type="protein sequence ID" value="CRG94071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526892.1">
        <property type="nucleotide sequence ID" value="XM_028670107.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNL6"/>
    <dbReference type="GeneID" id="39730310"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00178300"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="334" mass="37719" checksum="CC32F7E7532ED2A2" modified="2017-02-15" version="1">MLNYSTIIFYFYFLINSINLKTENFFTTWRTLAEEQATVPLVRIARSSSSMQNSLYRWLENIQEKFFSNIENVKSNSTGIDEVIQWVQNKTNILKHALNSTMDPGDRSFLSQTLNSWNNLTRTLLNTTFGLDFNDDPSSSNLLNMSTPSSTSPSFSTTDVSKAAENITTMISQNHTGISGLLPTTSSGIAQESSLGYSISEGCSGIFCESTTIALSLPFIIIGGLLFFVYLYKFTRIGTFLGRSNIKKERRKRRIYNVSMENIEDPYESSQETESMKSTLESSEETEAKRSRLENSEKTGAKRSGFSSLAKAFGYKYRNIFPYVDSNSYENETV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNP1</accession>
    <name>A0A1J1GNP1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00178600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000021">
        <property type="protein sequence ID" value="CRG94074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526895.1">
        <property type="nucleotide sequence ID" value="XM_028670110.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNP1"/>
    <dbReference type="GeneID" id="39730313"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00178600"/>
    <dbReference type="OrthoDB" id="6362699at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="311"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="343" mass="40783" checksum="EF0BDA891303A6C2" modified="2017-02-15" version="1">MALLYNEGCEYSEGDLTKCNMNICHISQNKFVTSLCKIHSPVVDIKKPSNNNLNDLSKNVFTHEYNPSNFHSRITILSNNDRDGILLLYEYNPYHNKYPEKTYLCRLRNIKQKLTLCEYINMEYIGRSLTFDSYDIINEESKNNNMISLKNPNHKIIKSKYDKLIFKEHFCHHMKTKYISYCNKRNTICKKINNDQLHCTDANYSGHLIKLDHIEYYVLKRKHIYLPSGCLKENLNPVCTPHICISHAINEFFECEYQEISVIKNIRPIKKIMPIKEIRPIKNIRTNSNNLAMTSLKHEDIYHKNSFYNTALFAMSFMSFLVLFTFFFCLLYRTFRKKRRKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNW1</accession>
    <name>A0A1J1GNW1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Chromatin target of PRMT1 protein C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00067100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG92967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525789.1">
        <property type="nucleotide sequence ID" value="XM_028670310.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNW1"/>
    <dbReference type="GeneID" id="39729196"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00067100"/>
    <dbReference type="OrthoDB" id="385632at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025715">
        <property type="entry name" value="FoP_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13865">
        <property type="entry name" value="FoP_duplication"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01218">
        <property type="entry name" value="FoP_duplication"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Chromatin target of PRMT1 protein C-terminal" evidence="2">
        <location>
            <begin position="25"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG92967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="126" mass="15303" checksum="8F7AE6838E748BF6" modified="2017-02-15" version="1">MNRKYFNRGNAFFSRNKRKLGNKFEDRIFGNSNEHDFYLRKTKNNNFRKRRNSFRSNRRRNFFYKRNQNLHDKIGKLTSKDLDDELDKYMGSTNVKTRLDNDLDSYFKNNALTQVDVNKGFNKVPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNZ2</accession>
    <name>A0A1J1GNZ2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ubiquitin-activating enzyme, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00171900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526833.1">
        <property type="nucleotide sequence ID" value="XM_028670041.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNZ2"/>
    <dbReference type="GeneID" id="39730246"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00171900"/>
    <dbReference type="OMA" id="SNCYRCL"/>
    <dbReference type="OrthoDB" id="10261062at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004792">
        <property type="term" value="F:thiosulfate-cyanide sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042292">
        <property type="term" value="F:URM1 activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00757">
        <property type="entry name" value="ThiF_MoeB_HesA_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000033">
        <property type="entry name" value="Adenylyltransferase and sulfurtransferase MOCS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF102">
        <property type="entry name" value="ADENYLYLTRANSFERASE AND SULFURTRANSFERASE MOCS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="4">
        <location>
            <begin position="88"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="517" mass="60488" checksum="38CC210A7DAB2109" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP50</accession>
    <name>A0A1J1GP50_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Kinesin-8, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00396900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527086.1">
        <property type="nucleotide sequence ID" value="XM_028670323.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP50"/>
    <dbReference type="GeneID" id="39732499"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00396900"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00106">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000112">
        <property type="entry name" value="Kinesin-8, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968">
        <property type="entry name" value="CENTROMERE PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968:SF13">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KIF19 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0493">Microtubule</keyword>
    <keyword evidence="5 6" id="KW-0505">Motor protein</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="8">
        <location>
            <begin position="313"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="652"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="400"/>
            <end position="407"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1166" mass="135657" checksum="5F0407EEFE12E272" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPE4</accession>
    <name>A0A1J1GPE4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sugar transporter SWEET1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PGAL8A_00407300</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SWEET sugar transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527190.1">
        <property type="nucleotide sequence ID" value="XM_028670438.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPE4"/>
    <dbReference type="GeneID" id="39732603"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00407300"/>
    <dbReference type="OMA" id="FCYGFII"/>
    <dbReference type="OrthoDB" id="409725at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051119">
        <property type="term" value="F:sugar transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000025">
        <property type="entry name" value="MtN3-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000004">
        <property type="entry name" value="Sugar transporter SWEET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047664">
        <property type="entry name" value="SWEET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004316">
        <property type="entry name" value="SWEET_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10791">
        <property type="entry name" value="RAG1-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10791:SF30">
        <property type="entry name" value="SUGAR TRANSPORTER SWEET1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03083">
        <property type="entry name" value="MtN3_slv"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="15" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="8 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013063014" description="Sugar transporter SWEET1" evidence="15">
        <location>
            <begin position="23"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="252"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="288"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="312"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="343"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="372"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="404"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="430"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="74"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="74"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="CRG94369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="547" mass="62809" checksum="79470786BE7A86F3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPH6</accession>
    <name>A0A1J1GPH6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2 NT-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00089500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526013.1">
        <property type="nucleotide sequence ID" value="XM_028671499.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPH6"/>
    <dbReference type="GeneID" id="39729419"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00089500"/>
    <dbReference type="OrthoDB" id="387147at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019448">
        <property type="entry name" value="NT-C2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51840">
        <property type="entry name" value="C2_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2 NT-type" evidence="2">
        <location>
            <begin position="8"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="343"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="472"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="732"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="874"/>
            <end position="908"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="927" mass="110810" checksum="47F0D95B18871ABA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPR4</accession>
    <name>A0A1J1GPR4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00189400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000026">
        <property type="protein sequence ID" value="CRG94498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527316.1">
        <property type="nucleotide sequence ID" value="XM_028670578.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPR4"/>
    <dbReference type="GeneID" id="39730420"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00189400"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="172" mass="20939" checksum="0D43984E3C455A0D" modified="2017-02-15" version="1">MKSLTLYLKITTFLLLIWMYQCFYNCYSYITLTGKNILETKNELKYERVLTEGDIVGNKQTNDKGCLEECPLDNEKNIWENPVKYRDPYNFWYKIIIPQLWKRFDKETSGMSPNSKNRKWNIEWHKISTTKVNDLHLMSRRRDIPDEEKNKIIDRVMKELELQFKEFLFECK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ00</accession>
    <name>A0A1J1GQ00_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Ubiquinol-cytochrome c reductase iron-sulfur, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PGAL8A_00198600</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Rieske iron-sulfur protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527404.1">
        <property type="nucleotide sequence ID" value="XM_028670675.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ00"/>
    <dbReference type="GeneID" id="39730513"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00198600"/>
    <dbReference type="OMA" id="TICKSVH"/>
    <dbReference type="OrthoDB" id="1637982at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008121">
        <property type="term" value="F:quinol-cytochrome-c reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03470">
        <property type="entry name" value="Rieske_cytochrome_bc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.102.10.10:FF:000001">
        <property type="entry name" value="Cytochrome b-c1 complex subunit Rieske, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014349">
        <property type="entry name" value="Rieske_Fe-S_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005805">
        <property type="entry name" value="Rieske_Fe-S_prot_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006317">
        <property type="entry name" value="Ubiquinol_cyt_c_Rdtase_Fe-S-su"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01416">
        <property type="entry name" value="Rieske_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10134">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00162">
        <property type="entry name" value="RIESKE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81502">
        <property type="entry name" value="ISP transmembrane anchor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="192"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="Rieske" evidence="13">
        <location>
            <begin position="259"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG94589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="355" mass="40917" checksum="C66180BCE957128E" modified="2017-02-15" version="1">MIRIKNINIFQQCSLLKKNQLYKLSKRFGGTFHHNIKENEKIPPASENPSYKNLFDHAEDIKLWEIEEKANISHKKVEDLSELVEPSNHPHQYEGFFVRTRYAHYNQTAEPLFPRKPDLEKGELASGANVTRTDVWHNPNEPAVVSVGKFEPSNFRPAGYAENAPNPDSINSEYHPDFREYRLRKGHADRRTFMYFISASYFFIMSSIMRSTICKVVHFWWISRDLVAAGTTEVDIKSVSPGQQVIIKWRGKPVFVKHRTPDEIERAKEEDKLVETMKDPQLDSDRTIKPEWLINIGVCTHLGCIPVEGGNFNGYFCPCHGSHYDNSGRIRQGPAPSNLEIPPYEFIDENTIKIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ70</accession>
    <name>A0A1J1GQ70_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00198400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527402.1">
        <property type="nucleotide sequence ID" value="XM_028670673.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ70"/>
    <dbReference type="GeneID" id="39730511"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00198400"/>
    <dbReference type="OMA" id="CFSFIYN"/>
    <dbReference type="OrthoDB" id="381456at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="152"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="374"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1153" mass="138998" checksum="B129DE5199E75708" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ84</accession>
    <name>A0A1J1GQ84_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heme detoxification protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">HDP</name>
        <name evidence="2" type="ORF">PGAL8A_00206000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527478.1">
        <property type="nucleotide sequence ID" value="XM_028670758.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ84"/>
    <dbReference type="GeneID" id="39730587"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00206000"/>
    <dbReference type="OMA" id="EFKNCDH"/>
    <dbReference type="OrthoDB" id="286301at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAS1" evidence="1">
        <location>
            <begin position="47"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="205" mass="24134" checksum="55FA53FAECE97D5B" modified="2017-02-15" version="1">MKNSGYNLIIKRLYTRSGGLRKPQKVTNDPESINRKVYWCFEHKPIKRTIVNLIFSHKELKFFSNFLNHPNVGVSLIHELSLEGPFTGFLPSNEALKLINSECLNKLYKDDNKLSEFVLNHFTKDFWLYRDLYGSSYQPWLIYNEKREAPEKITNLMNNDLIVKIKGEFKNCDHSIYLNESKIIRPNMKCHNGVVHIVDKPIIFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQJ9</accession>
    <name>A0A1J1GQJ9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sodium-and chloride-dependent neutral and basic amino acid transporter, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00193800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000029">
        <property type="protein sequence ID" value="CRG94540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527355.1">
        <property type="nucleotide sequence ID" value="XM_028670620.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQJ9"/>
    <dbReference type="GeneID" id="39730463"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00193800"/>
    <dbReference type="OrthoDB" id="333653at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035725">
        <property type="term" value="P:sodium ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616:SF240">
        <property type="entry name" value="BLOATED TUBULES, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616">
        <property type="entry name" value="SODIUM/CHLORIDE DEPENDENT TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00176">
        <property type="entry name" value="NANEUSMPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SNF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="280"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="355"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="393"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="433"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="468"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="528"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="574"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="604"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="643"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="982"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="168"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1110" mass="131539" checksum="4D29FFE9F95DE4CC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQU3</accession>
    <name>A0A1J1GQU3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Serine aminopeptidase S33 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00111600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526232.1">
        <property type="nucleotide sequence ID" value="XM_028673932.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQU3"/>
    <dbReference type="GeneID" id="39729641"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00111600"/>
    <dbReference type="OMA" id="QYWTSED"/>
    <dbReference type="OrthoDB" id="10249433at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008474">
        <property type="term" value="F:palmitoyl-(protein) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277">
        <property type="entry name" value="ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277:SF81">
        <property type="entry name" value="PROTEIN ABHD13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="1">
        <location>
            <begin position="80"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="274" mass="32136" checksum="992FFA735150EB45" modified="2017-02-15" version="1">MYFYQDSYIFQYGKLEPNYEYTIGDNYEYVYLKTEEGYLHKCWFIKAEGQEKKPVILYFLGSGGIIEKHIDVFNKMIENLSVDIFSCSNRGSGTNEGKPTEKDLYKDAEIYLNYLKKENIPHIFVFGSSMGGAVAIEMALRHQDYITGLIIQNTFLSLKKLAKYTYPFLYYCLINYNLIIRSKMDNESKIKEIHIPTLFNISLKDKVVPPFHSNLLHELCPSIFKFLYLSPNGTHANITKDDEVKYYASFKEFVEFSVFLKERNEEKKNELLDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR40</accession>
    <name>A0A1J1GR40_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00233000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527746.1">
        <property type="nucleotide sequence ID" value="XM_028671055.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR40"/>
    <dbReference type="GeneID" id="39730857"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00233000"/>
    <dbReference type="OrthoDB" id="376802at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="371"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="371"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="819" mass="97107" checksum="2368A0A7187CFF89" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR87</accession>
    <name>A0A1J1GR87_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nucleotidyltransferase, putative</fullName>
            <ecNumber evidence="3">2.7.7.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00244600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527860.1">
        <property type="nucleotide sequence ID" value="XM_028671182.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR87"/>
    <dbReference type="GeneID" id="39730974"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00244600"/>
    <dbReference type="OMA" id="LWAQLIM"/>
    <dbReference type="OrthoDB" id="273917at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031499">
        <property type="term" value="C:TRAMP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990817">
        <property type="term" value="F:poly(A) RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043634">
        <property type="term" value="P:polyadenylation-dependent ncRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05402">
        <property type="entry name" value="NT_PAP_TUTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054708">
        <property type="entry name" value="MTPAP-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045862">
        <property type="entry name" value="Trf4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23092:SF15">
        <property type="entry name" value="INACTIVE NON-CANONICAL POLY(A) RNA POLYMERASE PROTEIN TRF4-2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23092">
        <property type="entry name" value="POLY(A) RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22600">
        <property type="entry name" value="MTPAP-like_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Poly(A) RNA polymerase mitochondrial-like central palm" evidence="2">
        <location>
            <begin position="348"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="200"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="757" mass="88816" checksum="9E9A610BB3110C7F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR92</accession>
    <name>A0A1J1GR92_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00237800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527794.1">
        <property type="nucleotide sequence ID" value="XM_028671109.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730906"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00237800"/>
    <dbReference type="OMA" id="NICERNH"/>
    <dbReference type="OrthoDB" id="378010at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="786"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1977"/>
            <end position="2007"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="384"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="485"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="618"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="740"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1290"/>
            <end position="1324"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2232"/>
            <end position="2273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2489" mass="297427" checksum="A2529F28DBF047F3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRD4</accession>
    <name>A0A1J1GRD4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00249500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527908.1">
        <property type="nucleotide sequence ID" value="XM_028671236.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRD4"/>
    <dbReference type="GeneID" id="39731023"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00249500"/>
    <dbReference type="OMA" id="LIHYNNI"/>
    <dbReference type="OrthoDB" id="376043at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="639" mass="77467" checksum="CD4BE1AC2D80B0D8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRI8</accession>
    <name>A0A1J1GRI8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Parasitophorous vacuolar protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00247600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527890.1">
        <property type="nucleotide sequence ID" value="XM_028671216.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRI8"/>
    <dbReference type="GeneID" id="39731004"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00247600"/>
    <dbReference type="OMA" id="FEMEDEY"/>
    <dbReference type="OrthoDB" id="10630006at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012656050" description="Parasitophorous vacuolar protein 3" evidence="2">
        <location>
            <begin position="23"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="140" mass="15605" checksum="EC5C6153FCCF5D23" modified="2017-02-15" version="1">MILKNLFFIFVLLSIIVHFNKKYQCSSDYAQPNPFAQPEDEEQESSPSPTVLEREAPEAKADDGNVNGGNVGGNDNYGSFFGNDDGDDDDDDDDNDEDINETVDDDLDNDDDELLGDDDEDDDENPKKKKGNDDDNESEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRR7</accession>
    <name>A0A1J1GRR7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNase I-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00169900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526813.1">
        <property type="nucleotide sequence ID" value="XM_028670019.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRR7"/>
    <dbReference type="GeneID" id="39730226"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00169900"/>
    <dbReference type="OMA" id="KLYQLCY"/>
    <dbReference type="OrthoDB" id="10253982at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050410">
        <property type="entry name" value="CCR4/nocturin_mRNA_transcr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121">
        <property type="entry name" value="CARBON CATABOLITE REPRESSOR PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121:SF34">
        <property type="entry name" value="PROTEIN ANGEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="576"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="576"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="736" mass="88418" checksum="4F6A17CD89D64AA9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRT7</accession>
    <name>A0A1J1GRT7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00172300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526837.1">
        <property type="nucleotide sequence ID" value="XM_028670046.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRT7"/>
    <dbReference type="GeneID" id="39730250"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00172300"/>
    <dbReference type="OMA" id="IKHVSYI"/>
    <dbReference type="OrthoDB" id="371754at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="295" mass="34860" checksum="A5DF7213D44E8210" modified="2017-02-15" version="1">MRAFVDKQFRKSSESLKDDDEFYIERKHLNSLHNYFSHSLLYLERLESAIKNINIMISDLNTCLMSFFENDVNLEIIKHVSYILNSFNNVREQITSQITESKTMVNNTLNKIKNVQNLCIKKRHLSSSIEHYEKKIKKLQTVTTSNQKHLDKVIRNEHKLNKVKTDYLEYHENIKKGFDSILENKTNKVLFDARKKLKFFDKKTRKLPIEYNFFLEEEDKMNIFAEKKKNNNPFSYDIDNNENNTCKSSESSSIRIGSNDKKSNNIFKIKSFLKVTNKPSKIKTLPSNLPPIFPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRZ3</accession>
    <name>A0A1J1GRZ3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Trafficking protein particle complex subunit 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">TRAPPC2</name>
        <name evidence="1" type="ORF">PGAL8A_00244500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527859.1">
        <property type="nucleotide sequence ID" value="XM_028671181.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRZ3"/>
    <dbReference type="GeneID" id="39730973"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00244500"/>
    <dbReference type="OMA" id="RYMNQFI"/>
    <dbReference type="OrthoDB" id="10252102at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14825">
        <property type="entry name" value="TRAPPC2_sedlin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006722">
        <property type="entry name" value="Sedlin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12403">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04628">
        <property type="entry name" value="Sedlin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="162" mass="18538" checksum="83880512087CC389" modified="2017-02-15" version="1">MNRNIGNNSLLPYQVFVLTIIGKGDIPIYEADLSINGKKDISEHLAQFIIHQSLDSLDELVWRSSSMFLKSIDSFNNYSVSAYCTPGHIKFLLLFKNKNEINNSTNTNIYVPSDENIRSFFEIVHENYIKVLLNPLYEPNGIITSSLFDQNVHLAAKKFLHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS70</accession>
    <name>A0A1J1GS70_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Phosphatidylinositol 3-and 4-kinase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00010600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528150.1">
        <property type="nucleotide sequence ID" value="XM_028671504.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS70"/>
    <dbReference type="GeneID" id="39728628"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00010600"/>
    <dbReference type="OMA" id="IMPHIMD"/>
    <dbReference type="OrthoDB" id="5839at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044571">
        <property type="entry name" value="P4KG1-8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45800:SF11">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 3-KINASE-RELATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45800">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="7">
        <location>
            <begin position="163"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="701"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="701"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="716"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="735"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="754"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="769"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="786"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="796"/>
            <end position="823"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="919" mass="107663" checksum="72C39EF337784547" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSE0</accession>
    <name>A0A1J1GSE0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Tyrosine kinase-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">TKL3</name>
        <name evidence="11" type="ORF">PGAL8A_00260300</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528011.1">
        <property type="nucleotide sequence ID" value="XM_028671350.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731132"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00260300"/>
    <dbReference type="OrthoDB" id="371082at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09487">
        <property type="entry name" value="SAM_superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF288">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM" evidence="10">
        <location>
            <begin position="1052"/>
            <end position="1115"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="1145"/>
            <end position="1499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="186"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="943"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1222"/>
            <end position="1245"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="815"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1223"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="1172"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG95199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1515" mass="178676" checksum="1D7D53ABC855F2A0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSV9</accession>
    <name>A0A1J1GSV9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00010300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528147.1">
        <property type="nucleotide sequence ID" value="XM_028671501.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSV9"/>
    <dbReference type="GeneID" id="39728625"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00010300"/>
    <dbReference type="OrthoDB" id="390922at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="188" mass="22807" checksum="A245F13180AE34BB" modified="2017-02-15" version="1">MFNIDLGKPEVDLTVCDYTDIQMYVSLLRYEYKFEPWSNDSRYLYSHENMQRIIKELNILMKSKIPSFSVFFISTFSYALMVTSYVGIFIFYIIEYDLFIAFLFSCLFLIAFVHYIMCMIYRYIVTKSVIESIEKRIKHLNKKYKDEQIYFKLINFSGLGFKYLKILPTFRGQKYFTLRVIYMYCKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTR3</accession>
    <name>A0A1J1GTR3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Signal peptidase complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00305100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Dispensable for SPC enzymatic activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SPCS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528647.1">
        <property type="nucleotide sequence ID" value="XM_028672056.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTR3"/>
    <dbReference type="GeneID" id="39731584"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00305100"/>
    <dbReference type="OMA" id="IHLTLWT"/>
    <dbReference type="OrthoDB" id="263893at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005787">
        <property type="term" value="C:signal peptidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045047">
        <property type="term" value="P:protein targeting to ER"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009542">
        <property type="entry name" value="Spc1/SPCS1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13202">
        <property type="entry name" value="MICROSOMAL SIGNAL PEPTIDASE 12 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13202:SF0">
        <property type="entry name" value="SIGNAL PEPTIDASE COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06645">
        <property type="entry name" value="SPC12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="30"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00045204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG95839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="101" mass="11791" checksum="7298CEF7157331F3" modified="2017-02-15" version="1">MSTFKDIKSIIQNTYFCLKRNQMDFVGQKLAFLIKNIIFTISTILAIVIGYYYQNLALSAYIILAGTLMATILVLPTWPMYNRNNIEWSKDEDSLKEKKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTS1</accession>
    <name>A0A1J1GTS1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cysteine repeat modular protein 3, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CRMP3</name>
        <name evidence="5" type="ORF">PGAL8A_00313900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528734.1">
        <property type="nucleotide sequence ID" value="XM_028672152.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731672"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00313900"/>
    <dbReference type="OMA" id="NYQNRCW"/>
    <dbReference type="OrthoDB" id="410989at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00185">
        <property type="entry name" value="TNFRSF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.50.10">
        <property type="entry name" value="Tumor Necrosis Factor Receptor, subunit A, domain 2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056048">
        <property type="entry name" value="CRMPA/B-like_DUF7631"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052071">
        <property type="entry name" value="SCUB_EGF-like_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011641">
        <property type="entry name" value="Tyr-kin_ephrin_A/B_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24046:SF5">
        <property type="entry name" value="EGF-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24046">
        <property type="entry name" value="SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24634">
        <property type="entry name" value="DUF7631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07699">
        <property type="entry name" value="Ephrin_rec_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM01411">
        <property type="entry name" value="Ephrin_rec_like"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012407673" evidence="3">
        <location>
            <begin position="22"/>
            <end position="3351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2247"/>
            <end position="2266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2278"/>
            <end position="2298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2359"/>
            <end position="2379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2533"/>
            <end position="2554"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2575"/>
            <end position="2596"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2625"/>
            <end position="2647"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2683"/>
            <end position="2702"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2708"/>
            <end position="2728"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2740"/>
            <end position="2757"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2763"/>
            <end position="2783"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="4">
        <location>
            <begin position="917"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="4">
        <location>
            <begin position="984"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="4">
        <location>
            <begin position="1030"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="4">
        <location>
            <begin position="1727"/>
            <end position="1776"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3247"/>
            <end position="3278"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3321"/>
            <end position="3348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3351" mass="398432" checksum="FDECDEA5E66C410F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTT2</accession>
    <name>A0A1J1GTT2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="6">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00290900</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="6">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528513.1">
        <property type="nucleotide sequence ID" value="XM_028671907.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTT2"/>
    <dbReference type="GeneID" id="39731442"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00290900"/>
    <dbReference type="OMA" id="DYATCIC"/>
    <dbReference type="OrthoDB" id="7396459at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025313">
        <property type="entry name" value="SPB4-like_CTE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13959">
        <property type="entry name" value="CTE_SPB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01178">
        <property type="entry name" value="DUF4217"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="3 6 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="647"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="39"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="428"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="742"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="858"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="742"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="767"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="777"/>
            <end position="791"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG95705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="881" mass="106459" checksum="289D3CF561D2CBF0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTY2</accession>
    <name>A0A1J1GTY2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00190000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000027">
        <property type="protein sequence ID" value="CRG94503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_028670582.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTY2"/>
    <dbReference type="GeneID" id="39730425"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00190000"/>
    <dbReference type="OMA" id="YSIVNFN"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006496">
        <property type="entry name" value="CHP01606_Plasmodium_spp"/>
    </dbReference>
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        <property type="entry name" value="Wx5_PLAF3D7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="118"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="242" mass="29223" checksum="C478CF91A3D59189" modified="2017-02-15" version="1">MDKDKRLFVSTLFIQLLKSHHKIVRVNVLIVFLNITIFYLLICICRCFCITKDSVKYFNCKYVLNDKLKVGYERCLSEADEHELLHGFYIPESKVEERTVNQEDSPEESYDSDDSYSEENNSANYNDNGESLQMELLRDLCKKLSYIWISFYFEMQEIYQEKTRRMNSSWRFNMWYSEWVSYLKLCHGIIMRMMVNLNLSIEYKESNFHSWLNFISRDFQSFLKKVEQNWIGCKITTDDLDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTZ8</accession>
    <name>A0A1J1GTZ8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00320100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528796.1">
        <property type="nucleotide sequence ID" value="XM_028672223.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTZ8"/>
    <dbReference type="GeneID" id="39731734"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00320100"/>
    <dbReference type="OMA" id="PILMYKE"/>
    <dbReference type="OrthoDB" id="386624at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="165" mass="19396" checksum="708E340EC4A674F9" modified="2017-02-15" version="1">METNCIQDEDLYTISKKKAMIFFIISLFLAFFKVVLFIFDTLAFCILIIFILLSMFLGYSGLISRNPSLVCAKAYVGVVFFCIMLDFLISFLCCCYIYRLAVGDYDYMHITKVDYIYSYFIFISVVVFCLLSTIINIFSIYYTRKFKKLIIPFQMRNEKKDVCLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU51</accession>
    <name>A0A1J1GU51_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Large ribosomal subunit associated GTPase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00302900</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528625.1">
        <property type="nucleotide sequence ID" value="XM_028672031.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU51"/>
    <dbReference type="GeneID" id="39731562"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00302900"/>
    <dbReference type="OrthoDB" id="61815at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01857">
        <property type="entry name" value="HSR1_MMR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043358">
        <property type="entry name" value="GNL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45709:SF2">
        <property type="entry name" value="LARGE SUBUNIT GTPASE 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45709">
        <property type="entry name" value="LARGE SUBUNIT GTPASE 1 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G" evidence="6">
        <location>
            <begin position="603"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="186"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="194"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="210"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="836" mass="99330" checksum="77719878B7BC7C6A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU73</accession>
    <name>A0A1J1GU73_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Copper transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00198200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527400.1">
        <property type="nucleotide sequence ID" value="XM_028670671.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU73"/>
    <dbReference type="GeneID" id="39730509"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00198200"/>
    <dbReference type="OMA" id="FQNTTHT"/>
    <dbReference type="OrthoDB" id="73901at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005375">
        <property type="term" value="F:copper ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007274">
        <property type="entry name" value="Cop_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483:SF27">
        <property type="entry name" value="COPPER TRANSPORT PROTEIN CTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04145">
        <property type="entry name" value="Ctr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0186">Copper</keyword>
    <keyword evidence="5" id="KW-0187">Copper transport</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012498248" description="Copper transport protein" evidence="6">
        <location>
            <begin position="24"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="182"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG94585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="236" mass="27264" checksum="E9F781E36213031A" modified="2017-02-15" version="1">MNKYLASVLFIILILNSIDINAGSTNSKNNCTPDFTISCSHKCCKKKLAFIQECWDNYKKYSEIINEHKRNENNIIYSLEENMDLMGKGESMPMSFQFSTHTIILFKSWETLSKGSYYISLVVCFFFGLISVMLKVFRLNIERSLPKTKDRNVFKSETLFKNNTIRMILAFIIYSWDYLLMLIVMTFNVGLFFSVIFGLAFGFFLFGSHFVTSKKCATTDLDIHKQFYGDPACCGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUD2</accession>
    <name>A0A1J1GUD2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mitochondrial acidic protein MAM33</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00306300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528659.1">
        <property type="nucleotide sequence ID" value="XM_028672069.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUD2"/>
    <dbReference type="GeneID" id="39731596"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00306300"/>
    <dbReference type="OMA" id="RWLNNVK"/>
    <dbReference type="OrthoDB" id="278212at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.280.10:FF:000004">
        <property type="entry name" value="Mitochondrial acidic protein MAM33, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.280.10">
        <property type="entry name" value="Mitochondrial glycoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003428">
        <property type="entry name" value="MAM33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036561">
        <property type="entry name" value="MAM33_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10826">
        <property type="entry name" value="COMPLEMENT COMPONENT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10826:SF1">
        <property type="entry name" value="COMPLEMENT COMPONENT 1 Q SUBCOMPONENT-BINDING PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02330">
        <property type="entry name" value="MAM33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54529">
        <property type="entry name" value="Mitochondrial glycoprotein MAM33-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="252" mass="29058" checksum="010123B2F1DA0A5E" modified="2017-02-15" version="1">MNFIFRNTVNLSKSKPFNKQISNSVNRLANLNKRKITNINNIGKYDQRLQTNFSAINKRTFSSSESQKLLEVVKAEVQHEKSNYEAPENIKKFLQTSGWKYEEQEGDVNMVLTKNVDGMKIIVDFQLVSPFQAEGENEAQAEMTDFSVTVEKPNKQGGITFYCTTLQNDEKFRYMIGNVKYYKNEEGKNSVSSYNGPEFEDLDDSLQTSLDEWLANLGVDSELCDFIDSCSIDKEQREYMSWLQNISNFIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUG9</accession>
    <name>A0A1J1GUG9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA helicase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00339500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528982.1">
        <property type="nucleotide sequence ID" value="XM_028672429.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUG9"/>
    <dbReference type="GeneID" id="39731925"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00339500"/>
    <dbReference type="OMA" id="PLHKLYQ"/>
    <dbReference type="OrthoDB" id="10265467at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008047">
        <property type="term" value="F:enzyme activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000731">
        <property type="term" value="P:DNA synthesis involved in DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18139">
        <property type="entry name" value="HLD_clamp_RarA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.272.10:FF:000001">
        <property type="entry name" value="Putative AAA family ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051314">
        <property type="entry name" value="AAA_ATPase_RarA/MGS1/WRNIP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021886">
        <property type="entry name" value="MgsA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13779:SF7">
        <property type="entry name" value="ATPASE WRNIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13779">
        <property type="entry name" value="WERNER HELICASE-INTERACTING PROTEIN 1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12002">
        <property type="entry name" value="MgsA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14532">
        <property type="entry name" value="Sigma54_activ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="6">
        <location>
            <begin position="136"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="MgsA AAA+ ATPase C-terminal" evidence="5">
        <location>
            <begin position="386"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="71"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="28"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="78"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="532" mass="62181" checksum="1CC4DE3B61219D82" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUH7</accession>
    <name>A0A1J1GUH7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Translocon component PTEX88, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00332900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528919.1">
        <property type="nucleotide sequence ID" value="XM_028672359.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUH7"/>
    <dbReference type="GeneID" id="39731859"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00332900"/>
    <dbReference type="OMA" id="IMNNKEM"/>
    <dbReference type="OrthoDB" id="391178at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63825">
        <property type="entry name" value="YWTD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012136499" evidence="1">
        <location>
            <begin position="18"/>
            <end position="727"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="727" mass="85328" checksum="D789865A58D40940" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUR1</accession>
    <name>A0A1J1GUR1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RING zinc finger protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00349900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529086.1">
        <property type="nucleotide sequence ID" value="XM_028672545.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUR1"/>
    <dbReference type="GeneID" id="39732029"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00349900"/>
    <dbReference type="OMA" id="WFKTTNT"/>
    <dbReference type="OrthoDB" id="265776at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16514">
        <property type="entry name" value="RING-HC_LONFs_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23327">
        <property type="entry name" value="RING FINGER PROTEIN 127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23327:SF51">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR OF YEAST FORM ADHERENCE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="521"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="137"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="26"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="80"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="547" mass="63933" checksum="3C5CCAC760B300EF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUZ1</accession>
    <name>A0A1J1GUZ1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00359300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529174.1">
        <property type="nucleotide sequence ID" value="XM_028672641.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUZ1"/>
    <dbReference type="GeneID" id="39732123"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00359300"/>
    <dbReference type="OrthoDB" id="377340at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="5"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="537"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="645" mass="77656" checksum="4C613F2450BEFDB2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV73</accession>
    <name>A0A1J1GV73_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Splicing factor 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">SF1</name>
        <name evidence="7" type="ORF">PGAL8A_00233600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527752.1">
        <property type="nucleotide sequence ID" value="XM_028671061.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV73"/>
    <dbReference type="GeneID" id="39730863"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00233600"/>
    <dbReference type="OMA" id="RYFAGNT"/>
    <dbReference type="OrthoDB" id="5411533at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12283">
        <property type="entry name" value="RRM1_RBM39_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12285">
        <property type="entry name" value="RRM3_RBM39_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029123">
        <property type="entry name" value="RBM39_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006509">
        <property type="entry name" value="RBM39_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01622">
        <property type="entry name" value="SF-CC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48036">
        <property type="entry name" value="SPLICING FACTOR (PAD-1), PUTATIVE (AFU_ORTHOLOGUE AFUA_1G15810)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15519">
        <property type="entry name" value="RBM39linker"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="479"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="578"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="757"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="95"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="184"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="184"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="230"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="260"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="273"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="326"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="338"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="376"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="392"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG94938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="852" mass="100288" checksum="3DF3F2853B4B7F8E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV89</accession>
    <name>A0A1J1GV89_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">N-alpha-acetyltransferase 40</fullName>
            <ecNumber evidence="4">2.3.1.257</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00235200</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>N-terminal L-seryl-[histone H2A] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-seryl-[histone H2A] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50600"/>
            <dbReference type="Rhea" id="RHEA-COMP:12742"/>
            <dbReference type="Rhea" id="RHEA-COMP:12744"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:64738"/>
            <dbReference type="ChEBI" id="CHEBI:83690"/>
            <dbReference type="EC" id="2.3.1.257"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>N-terminal L-seryl-[histone H4] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-seryl-[histone H4] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:50596"/>
            <dbReference type="Rhea" id="RHEA-COMP:12740"/>
            <dbReference type="Rhea" id="RHEA-COMP:12743"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:64738"/>
            <dbReference type="ChEBI" id="CHEBI:83690"/>
            <dbReference type="EC" id="2.3.1.257"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the acetyltransferase family. NAA40 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.257" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527768.1">
        <property type="nucleotide sequence ID" value="XM_028671079.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV89"/>
    <dbReference type="GeneID" id="39730880"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00235200"/>
    <dbReference type="OMA" id="RYADQRV"/>
    <dbReference type="OrthoDB" id="424551at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043998">
        <property type="term" value="F:histone H2A acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010485">
        <property type="term" value="F:histone H4 acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990189">
        <property type="term" value="F:protein N-terminal-serine acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039949">
        <property type="entry name" value="NAA40"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20531">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20531:SF1">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="12">
        <location>
            <begin position="152"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG94955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="313" mass="37710" checksum="39F6A98DDD7CADE5" modified="2017-02-15" version="1">METLHINKRINKKKKKENNSKYKIRDQKNIEFLKSYIKNKNKTIYKNEKNNINDGNIKSIYNEKDKIQLIRNCKNNDNIFDFIDIKYKKYFLENKDNNDSNICQFVFFESINAYELKKYNLSKKVFNIILEITKNNMKKMYNESNFLNKGWSDIRKMKELKNDKSKLILGFLKVNIKMKNEEKYNFLDIIKSNDQKKIDNYLQNYKLICFVHFRLTPDYYPYQKNIICYLYEIQIIPNYTKLGLGVHLISMLENLCKNIKLKKIICTVLKKNIRAISFYKNKCSFEIDENSPDNFITDNSESCEYEILKKVIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVA4</accession>
    <name>A0A1J1GVA4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcription factor with AP2 domain(S), putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ApiAP2</name>
        <name evidence="2" type="ORF">PGAL8A_00370600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529286.1">
        <property type="nucleotide sequence ID" value="XM_028672767.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732236"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00370600"/>
    <dbReference type="OMA" id="MNNENMS"/>
    <dbReference type="OrthoDB" id="372949at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2050">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1700"/>
            <end position="1719"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1893"/>
            <end position="1919"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="317"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="342"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="360"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="523"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="562"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="580"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="608"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="659"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="695"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="794"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1700"/>
            <end position="1716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1901"/>
            <end position="1919"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1937" mass="224763" checksum="F8CD7FA443865922" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVB2</accession>
    <name>A0A1J1GVB2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP-dependent (S)-NAD(P)H-hydrate dehydratase</fullName>
            <ecNumber evidence="6">4.2.1.93</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ATP-dependent NAD(P)HX dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00371400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(6S)-NADHX + ATP = ADP + phosphate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19017"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:64074"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.2.1.93"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(6S)-NADPHX + ATP = ADP + phosphate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:32231"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.2.1.93"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the NnrD/CARKD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.93" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529294.1">
        <property type="nucleotide sequence ID" value="XM_028672775.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVB2"/>
    <dbReference type="GeneID" id="39732244"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00371400"/>
    <dbReference type="OMA" id="IMNSIPH"/>
    <dbReference type="OrthoDB" id="8110916at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047453">
        <property type="term" value="F:ATP-dependent NAD(P)H-hydrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110051">
        <property type="term" value="P:metabolite repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046496">
        <property type="term" value="P:nicotinamide nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01171">
        <property type="entry name" value="YXKO-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01965">
        <property type="entry name" value="NADHX_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000631">
        <property type="entry name" value="CARKD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12592:SF0">
        <property type="entry name" value="ATP-DEPENDENT (S)-NAD(P)H-HYDRATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12592">
        <property type="entry name" value="ATP-DEPENDENT (S)-NAD(P)H-HYDRATE DEHYDRATASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01256">
        <property type="entry name" value="Carb_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51383">
        <property type="entry name" value="YJEF_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 6" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="YjeF C-terminal" evidence="7">
        <location>
            <begin position="26"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="193"/>
            <end position="199"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="232"/>
            <end position="236"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="259"/>
            <end position="268"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="357" mass="41086" checksum="DA0152546D67F48D" modified="2017-02-15" version="1">MEEFNICSNLLLNSIDLNRKLHNRDLYHLKDYIIPELSESDYKGCSGKICVIGGNEVYCGAPFLSAMTSLKLGADLCFVITSKENSIPLKSYSCELIVYPYLYNNKSEITEVKESDLEKCVEYLMNRIDSCVIGPGLGLIDETTRKCLIYIIEKFIEKNVFLILDADIIEFIISNNNLFELIKNYENCIFTPNKNEFKKMILLLTDDKSIKFEQIDSHQIIYSAHKMNLIFKGPKILIKGFYDIFISQNFFFVSFISNPCLKRLGGLGDILTGLLAVFYCWASKKKKKISQHIKEILNIDNTDHHNECLDALSAFNGSYFLKILCKEGFNKNHRGLIASDIMNSIPHYFYNIYDKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVC1</accession>
    <name>A0A1J1GVC1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00363400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529215.1">
        <property type="nucleotide sequence ID" value="XM_028672687.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVC1"/>
    <dbReference type="GeneID" id="39732164"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00363400"/>
    <dbReference type="OMA" id="NGYKNLM"/>
    <dbReference type="OrthoDB" id="383576at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="146" mass="17325" checksum="753B4D8128458479" modified="2017-02-15" version="1">MNENIPELILTHERKEKERLKKKRKKCKIYNTNYSFIYFLFLFNKNNLVEITTNNFDSLKGEIIEIKRNINNRLKGIVLTNVIKNNQTSFSFKKLYISILNVYTCLPINNNLNNNIKEKNISNVILNGYKNLMLNEIYKKFKKIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVC8</accession>
    <name>A0A1J1GVC8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ABC transporter B family member 3, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ABCB3</name>
        <name evidence="11" type="ORF">PGAL8A_00373000</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529310.1">
        <property type="nucleotide sequence ID" value="XM_028672793.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVC8"/>
    <dbReference type="GeneID" id="39732260"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00373000"/>
    <dbReference type="OMA" id="IPYYINP"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03228">
        <property type="entry name" value="ABCC_MRP_Like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF1">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012610885" evidence="8">
        <location>
            <begin position="21"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="219"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="321"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="407"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="183"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="577"/>
            <end position="801"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG96505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="801" mass="95558" checksum="3C48DD469B30174B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVN9</accession>
    <name>A0A1J1GVN9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sm protein F</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00353600</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529123.1">
        <property type="nucleotide sequence ID" value="XM_028672585.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVN9"/>
    <dbReference type="GeneID" id="39732066"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00353600"/>
    <dbReference type="OMA" id="GYMNVQL"/>
    <dbReference type="OrthoDB" id="409625at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034715">
        <property type="term" value="C:pICln-Sm protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01722">
        <property type="entry name" value="Sm_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016487">
        <property type="entry name" value="Lsm6/sSmF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034100">
        <property type="entry name" value="Sm_F"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11021:SF0">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11021">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN F SNRNP-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006609">
        <property type="entry name" value="snRNP_SmF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 10" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10 12" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 10" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="11">
        <location>
            <begin position="9"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR006609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG96318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="86" mass="9948" checksum="2164D3AD56D92B2C" modified="2017-02-15" version="1">MSVGIAPLNPKPFLNSLAGKRVVIKLKWGMEYKGNLKSFDAYMNIRLINAEEWIHGDYKGTLGEIFLRCNNILYIREENEKSKTEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVS4</accession>
    <name>A0A1J1GVS4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00412000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000061">
        <property type="protein sequence ID" value="CRG96538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529343.1">
        <property type="nucleotide sequence ID" value="XM_028672829.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVS4"/>
    <dbReference type="GeneID" id="39732650"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00412000"/>
    <dbReference type="OMA" id="YENESKY"/>
    <dbReference type="OrthoDB" id="371302at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="97" mass="11783" checksum="2DBD5BDDD8C4ABB2" modified="2017-02-15" version="1">MDYEDLTYLTSDDEYENESKYREPVPYITINRLDEDSDNIEKSLLSNNINDIDNSVDRLLKNSERIDVALSSIYDLEERQKKFKEEKKKYNFKRYLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVW6</accession>
    <name>A0A1J1GVW6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nucleoporin NUP138</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00416000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529383.1">
        <property type="nucleotide sequence ID" value="XM_028672874.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732691"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00416000"/>
    <dbReference type="OMA" id="SEQCDML"/>
    <dbReference type="OrthoDB" id="386105at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="568"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="735"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="833"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1131"/>
            <end position="1158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="568"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="670"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="684"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="749"/>
            <end position="761"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1345" mass="155640" checksum="D6417D5EA3852F35" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVX3</accession>
    <name>A0A1J1GVX3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00419400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529418.1">
        <property type="nucleotide sequence ID" value="XM_028672913.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVX3"/>
    <dbReference type="GeneID" id="39732726"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00419400"/>
    <dbReference type="OMA" id="FFFYYHS"/>
    <dbReference type="OrthoDB" id="378549at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="621" mass="75962" checksum="901EA2F6AFA44947" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVZ2</accession>
    <name>A0A1J1GVZ2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sporozoite surface protein essential for liver stage development</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00365500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529235.1">
        <property type="nucleotide sequence ID" value="XM_028672709.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVZ2"/>
    <dbReference type="GeneID" id="39732185"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00365500"/>
    <dbReference type="OMA" id="VEPFYYT"/>
    <dbReference type="OrthoDB" id="387505at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="143" mass="17263" checksum="6BDA984A1A675D07" modified="2017-02-15" version="1">MYRTYSVEPIIYNTYNCVYLKPKKTISSPFYYPLAVTGEYLLSSKTEGCCSSTRKYALYPESYFYPNYYYYYYYYPSYTTDNSYLNNYTYKDDDNTEKKKNDSEKKKEYEYVDRDKYVCNHFSVESSYVPKRAVYIPPTIIVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW74</accession>
    <name>A0A1J1GW74_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HIT-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00429800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529522.1">
        <property type="nucleotide sequence ID" value="XM_028673028.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW74"/>
    <dbReference type="GeneID" id="39732830"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00429800"/>
    <dbReference type="OrthoDB" id="18412at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007529">
        <property type="entry name" value="Znf_HIT"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51083">
        <property type="entry name" value="ZF_HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="HIT-type" evidence="2">
        <location>
            <begin position="108"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="251" mass="30151" checksum="AC167CF52CF7B603" modified="2017-02-15" version="1">MDEYEYNYSCDLENYPNNFENNVSYHDINYLNVDRTFDNFGNDLYLCDEAIEEDNEKEYFSSLNNNNLLKNEKELEKMINNNSIIKKRKICNDSIFNNKKVKNNENLCIICLKNEKKYKFTCCYEYYCSLQCFNKHNKKDCCKKKKKKLNEIKNTNSDNHGSLINNNFYVLNNNKIYESNEDYTEDNILTEEQKYKLKEDLELKLLLKNKYVRSIFKQFTSSNDKISYLSHYINDPTIIQVIDQIMKTIDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWD8</accession>
    <name>A0A1J1GWD8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 18">Inosine-5'-monophosphate dehydrogenase</fullName>
            <shortName evidence="12">IMP dehydrogenase</shortName>
            <shortName evidence="12">IMPD</shortName>
            <shortName evidence="12">IMPDH</shortName>
            <ecNumber evidence="12 18">1.1.1.205</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">PGAL8A_00433700</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 12">Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 12 18">
            <text>IMP + NAD(+) + H2O = XMP + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11708"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="1.1.1.205"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="12">Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12 18">Purine metabolism; XMP biosynthesis via de novo pathway; XMP from IMP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12 17">Belongs to the IMPDH/GMPR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.205" evidence="12 18"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529559.1">
        <property type="nucleotide sequence ID" value="XM_028673069.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWD8"/>
    <dbReference type="GeneID" id="39732869"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00433700"/>
    <dbReference type="OMA" id="MGYCGAK"/>
    <dbReference type="OrthoDB" id="418595at2759"/>
    <dbReference type="UniPathway" id="UPA00601">
        <property type="reaction ID" value="UER00295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003938">
        <property type="term" value="F:IMP dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006177">
        <property type="term" value="P:GMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006183">
        <property type="term" value="P:GTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04601">
        <property type="entry name" value="CBS_pair_IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00381">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000086">
        <property type="entry name" value="IMP dehydrogenase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01964">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005990">
        <property type="entry name" value="IMP_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015875">
        <property type="entry name" value="IMP_DH/GMP_Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001093">
        <property type="entry name" value="IMP_DH_GMPRt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01302">
        <property type="entry name" value="IMP_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11911:SF111">
        <property type="entry name" value="INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11911">
        <property type="entry name" value="INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00478">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000130">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01240">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00487">
        <property type="entry name" value="IMP_DH_GMP_RED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 16" id="KW-0129">CBS domain</keyword>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 12 18" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="3 12 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12 14" id="KW-0520">NAD</keyword>
    <keyword evidence="7 12 17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 12 15" id="KW-0630">Potassium</keyword>
    <keyword evidence="5 12 18" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="19">
        <location>
            <begin position="101"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="active site" description="Thioimidate intermediate" evidence="12 13">
        <location>
            <position position="314"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12 13">
        <location>
            <position position="413"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12 14">
        <location>
            <begin position="257"/>
            <end position="259"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12 14">
        <location>
            <begin position="307"/>
            <end position="309"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="12 15">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="12 15">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="12 15">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="347"/>
            <end position="349"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="370"/>
            <end position="371"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="394"/>
            <end position="398"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="435"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00056556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU003927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU003928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="CRG96755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="510" mass="56345" checksum="389CBD104C8C2596" modified="2017-02-15" version="1">MANGWNAEQIFGGVMSYTYDDIICMPGYIDFSLSEIDLCNNLTSNISLKTPIISSPMDTVTEHKMSISLALSGGLGLIHNNMSIENQIEEVKKVKRFENGFIFDPYTFSPENTVADVLETKKRVGYKSYPITVDGKVGSKLVGIITSVDYLYLTNKSKKIRDIMTTDVVTGNYPINLTDANKVLCEEKKSVLPIVNNNYELIALVCRNDMHKNKIFPYASKSKNKQLIVGAAISTREEDLERANQLIKNMIDVICIDSSQGNSIYQIDTIKKIKSAYPEVPIIGGNVVTCDQAKNLIDAGADILRIGMGSGSICTTQDVCAVGRAQGTAVYHVSNYAHTRNIKTIADGGIKNSGNIVKALSLGADFVMLGNLLAATEESCSDYYFENNVRLKIYRGMGSMEAMYNKNFNSKSRYLVEDKKISSFDDQNEEIKVSQGVSASLVDKGSVLNLIPHLVKAVKHGFQSMGIKNIQELHKKLYSGDLKFDVRSFNAIKEGKISDNLIFSNNKYTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWF6</accession>
    <name>A0A1J1GWF6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00446200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529684.1">
        <property type="nucleotide sequence ID" value="XM_028673208.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWF6"/>
    <dbReference type="GeneID" id="39732995"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00446200"/>
    <dbReference type="OMA" id="SIMQMVN"/>
    <dbReference type="OrthoDB" id="372153at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="660"/>
            <end position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="733" mass="87896" checksum="E62086AB09788857" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWF9</accession>
    <name>A0A1J1GWF9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA repair protein REV1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00423300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529457.1">
        <property type="nucleotide sequence ID" value="XM_028672956.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732765"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00423300"/>
    <dbReference type="OrthoDB" id="427711at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017125">
        <property type="term" value="F:deoxycytidyl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070987">
        <property type="term" value="P:error-free translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.100">
        <property type="entry name" value="DNA polymerase, Y-family, little finger domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036775">
        <property type="entry name" value="DNA_pol_Y-fam_lit_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001126">
        <property type="entry name" value="UmuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45990">
        <property type="entry name" value="DNA REPAIR PROTEIN REV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45990:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN REV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50173">
        <property type="entry name" value="UMUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="3">
        <location>
            <begin position="166"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="UmuC" evidence="4">
        <location>
            <begin position="562"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1162"/>
            <end position="1181"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="789"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1171"/>
            <end position="1181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1458" mass="174784" checksum="B4DAFBEE42ED976F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWJ9</accession>
    <name>A0A1J1GWJ9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Procollagen lysine 5-dioxygenase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00442800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529650.1">
        <property type="nucleotide sequence ID" value="XM_028673170.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWJ9"/>
    <dbReference type="GeneID" id="39732961"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00442800"/>
    <dbReference type="OMA" id="YSNIWYL"/>
    <dbReference type="OrthoDB" id="69177at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22997">
        <property type="entry name" value="GT_LH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057589">
        <property type="entry name" value="GT_PLOD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36587">
        <property type="entry name" value="EXPRESSION SITE-ASSOCIATED GENE 3 (ESAG3)-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36587:SF2">
        <property type="entry name" value="EXPRESSION SITE-ASSOCIATED GENE 3 (ESAG3)-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25342">
        <property type="entry name" value="GT_PLOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="442"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="498"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="domain" description="PLOD1-3-like GT" evidence="2">
        <location>
            <begin position="26"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="523" mass="62630" checksum="D234E8FBCF89BC28" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXG1</accession>
    <name>A0A1J1GXG1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RAP protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00483900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530062.1">
        <property type="nucleotide sequence ID" value="XM_028673628.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXG1"/>
    <dbReference type="GeneID" id="39733372"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00483900"/>
    <dbReference type="OMA" id="HYYTFGG"/>
    <dbReference type="OrthoDB" id="385235at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.960.10">
        <property type="entry name" value="VSR Endonuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013584">
        <property type="entry name" value="RAP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08373">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51286">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RAP" evidence="1">
        <location>
            <begin position="360"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="409" mass="49016" checksum="712896E79B2F5157" modified="2017-02-15" version="1" fragment="single">MIIKIIDSLIKKSSNSFFRRCLACYNHKVINMPKNDQIISNNFNIEDEMDKDKLIYLIKNIQIINLKDKNILNNISNLLKKYINDYNIEEIYLIIHSFCKLNFTKHSLYTNFVKIIMNKKPLMNTRMLTQILIDLHKLSSLDINVLTFFTEHYIKGSINKFSLFDLSMILFIYNKYNYNDFITINTICEIIKEYFLPIINEDKGVLTTILLSISTLNLNYEIYYYLLKKYIYKNYEHFEIKYLCNISYSIVLRLANNSIKDDLLNIILNDIITLLLNNLHKLKNEELKQIHIVLYYLRDEKEKYENAIKKIEKKNIKNTVTISKMQQQIEKIFKEIGIYVQKEYKIGPYILDFALKKKKICIEVNGFTHYYIFTSTLNAKTKLKYFILNKLNWNVVTIEYMDWKNKSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXG3</accession>
    <name>A0A1J1GXG3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">WD repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00021800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000082">
        <property type="protein sequence ID" value="CRG96928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529731.1">
        <property type="nucleotide sequence ID" value="XM_028673260.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXG3"/>
    <dbReference type="GeneID" id="39728740"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00021800"/>
    <dbReference type="OrthoDB" id="538223at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051179">
        <property type="entry name" value="WD_repeat_multifunction"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857:SF8">
        <property type="entry name" value="ANGIO-ASSOCIATED MIGRATORY CELL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857">
        <property type="entry name" value="MITOCHONDRIAL DIVISION PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="896" mass="106683" checksum="30F9F9A8841BB77D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXV2</accession>
    <name>A0A1J1GXV2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GDP dissociation inhibitor, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00496700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Rab GDI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530190.1">
        <property type="nucleotide sequence ID" value="XM_028673771.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXV2"/>
    <dbReference type="GeneID" id="39733500"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00496700"/>
    <dbReference type="OrthoDB" id="1923006at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005093">
        <property type="term" value="F:Rab GDP-dissociation inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.405.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.519.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018203">
        <property type="entry name" value="GDP_dissociation_inhibitor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787:SF8">
        <property type="entry name" value="RAB GDP DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787">
        <property type="entry name" value="RAB GDP-DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00996">
        <property type="entry name" value="GDI"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00891">
        <property type="entry name" value="RABGDIREP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="750"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="302"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="750"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="763"/>
            <end position="774"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="865" mass="102772" checksum="B9DF5FEB4E643B0F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXY6</accession>
    <name>A0A1J1GXY6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00490400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530127.1">
        <property type="nucleotide sequence ID" value="XM_028673701.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXY6"/>
    <dbReference type="GeneID" id="39733437"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00490400"/>
    <dbReference type="OrthoDB" id="380119at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="182" mass="22027" checksum="13C5C08DE6CE6CAF" modified="2017-02-15" version="1">MNEEKKNEKFIVKESIIYIKKYFALHDKTCASINELINIILNKNFNSNKGINEKETLTIIFKKELKYEFIKVYEILKITLEEMKKCIKKMKNFKNIIEESKTNSIILHSLHKFLKNTLIYFKRDYKLKENLHKAIIYVDETCENEINRIQLIWKETPFLFLIFQKFNTNKLIKDCELFLNKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY26</accession>
    <name>A0A1J1GY26_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Zinc finger protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00478500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530009.1">
        <property type="nucleotide sequence ID" value="XM_028673570.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733318"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00478500"/>
    <dbReference type="OMA" id="NINCGEK"/>
    <dbReference type="OrthoDB" id="411372at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="4">
        <location>
            <begin position="31"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="4">
        <location>
            <begin position="63"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="31"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="1">
        <location>
            <begin position="63"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="679"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1194"/>
            <end position="1258"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="530"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="935"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1198"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1243"/>
            <end position="1258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1652" mass="193714" checksum="A1BD5BD9697A0B80" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY37</accession>
    <name>A0A1J1GY37_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Zinc finger protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00313300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528728.1">
        <property type="nucleotide sequence ID" value="XM_028672146.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY37"/>
    <dbReference type="GeneID" id="39731666"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00313300"/>
    <dbReference type="OMA" id="HFQYFIW"/>
    <dbReference type="OrthoDB" id="10017393at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="477"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="642"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="689"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="725"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="764"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="789"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="935"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="180"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="180"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1010" mass="119752" checksum="D6443744D6B9FED9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY42</accession>
    <name>A0A1J1GY42_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00496000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530183.1">
        <property type="nucleotide sequence ID" value="XM_028673763.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY42"/>
    <dbReference type="GeneID" id="39733493"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00496000"/>
    <dbReference type="OMA" id="MYKLFLY"/>
    <dbReference type="OrthoDB" id="377793at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1084" mass="131546" checksum="E216922A0AB51718" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY57</accession>
    <name>A0A1J1GY57_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Serine/arginine-rich splicing factor 4, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SRSF4</name>
        <name evidence="9" type="ORF">PGAL8A_00481700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530041.1">
        <property type="nucleotide sequence ID" value="XM_028673605.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY57"/>
    <dbReference type="GeneID" id="39733350"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00481700"/>
    <dbReference type="OMA" id="YANIEHG"/>
    <dbReference type="OrthoDB" id="1099063at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000638">
        <property type="entry name" value="Serine/arginine-rich splicing factor 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003:SF62">
        <property type="entry name" value="SERINE_ARGININE (SR)-TYPE SHUTTLING MRNA BINDING PROTEIN NPL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="13"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="113"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="193"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="220"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="239"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="265"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="278"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="288"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="312"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="351"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="432"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="459"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="494"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="508"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG97238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="632" mass="73688" checksum="93DFA752A4F8BF44" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYB1</accession>
    <name>A0A1J1GYB1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zinc finger, C3HC4 type, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00487400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530097.1">
        <property type="nucleotide sequence ID" value="XM_028673668.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYB1"/>
    <dbReference type="GeneID" id="39733407"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00487400"/>
    <dbReference type="OMA" id="NDIFTRW"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010182">
        <property type="term" value="P:sugar mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044793">
        <property type="entry name" value="SIS3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47179">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SIS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47179:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SIS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="89"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="133"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="221"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="275" mass="33120" checksum="CC8CF91157B19A38" modified="2017-02-15" version="1">MIKMESERDRIRIKITFNDFILILSVCYSIADIFIQWKNFSKCYKPIQLWLVISFISIVLFRLSHFLAQHLSNENDHFIIYRRNNPPNFINFLVLCVLFPFFIIWNIIGTIWIYKIIKYTPNCLPSNNHPWFIVLWIVLCYIWILLYLFFIILSIYLEYQSRIYERAFTNMQSNDIFSRWSDNIDLIRNYGIFIYRKGLRLKQIENLPFYYIKDVSQETKCSICLNDFQVDECVRTLLLCNHTFHKSCIDLWLIRSATCPNCKSPIATQGVFMNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYP7</accession>
    <name>A0A1J1GYP7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00494000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530163.1">
        <property type="nucleotide sequence ID" value="XM_028673740.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733473"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00494000"/>
    <dbReference type="OMA" id="NFFFYKK"/>
    <dbReference type="OrthoDB" id="371480at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051023">
        <property type="entry name" value="PP2A_Regulatory_Subunit_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10648">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10648:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="806"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="830"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="506"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1000"/>
            <end position="1219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="509"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="523"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1000"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1042"/>
            <end position="1123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1129"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1208"/>
            <end position="1219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1582" mass="189272" checksum="3435C762EFF51911" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYR3</accession>
    <name>A0A1J1GYR3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphodiesterase</fullName>
            <ecNumber evidence="6">3.1.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">PDEbeta</name>
        <name evidence="9" type="ORF">PGAL8A_00517800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="6">Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cyclic nucleotide phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.-" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530406.1">
        <property type="nucleotide sequence ID" value="XM_028674011.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYR3"/>
    <dbReference type="GeneID" id="39733711"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00517800"/>
    <dbReference type="OMA" id="HVTNMIQ"/>
    <dbReference type="OrthoDB" id="189220at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004114">
        <property type="term" value="F:3',5'-cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1300.10">
        <property type="entry name" value="3'5'-cyclic nucleotide phosphodiesterase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023088">
        <property type="entry name" value="PDEase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002073">
        <property type="entry name" value="PDEase_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036971">
        <property type="entry name" value="PDEase_catalytic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023174">
        <property type="entry name" value="PDEase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11347">
        <property type="entry name" value="CYCLIC NUCLEOTIDE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00233">
        <property type="entry name" value="PDEase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00387">
        <property type="entry name" value="PDIESTERASE1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00126">
        <property type="entry name" value="PDEASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51845">
        <property type="entry name" value="PDEASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="420"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="453"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="486"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="525"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="560"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="583"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="domain" description="PDEase" evidence="8">
        <location>
            <begin position="762"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="837"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="837"/>
            <end position="841"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="841"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="877"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="878"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="878"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="878"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="990"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="990"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="1042"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG97605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1129" mass="132365" checksum="082B0E1D1D371094" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYW6</accession>
    <name>A0A1J1GYW6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Thrombospondin-related apical membrane protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">TRAMP</name>
        <name evidence="5" type="ORF">PGAL8A_00532600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530549.1">
        <property type="nucleotide sequence ID" value="XM_028674169.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYW6"/>
    <dbReference type="GeneID" id="39733859"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00532600"/>
    <dbReference type="OrthoDB" id="446173at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.100.10">
        <property type="entry name" value="Thrombospondin type-1 (TSP1) repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021805">
        <property type="entry name" value="Pept_M10A_metallopeptidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000884">
        <property type="entry name" value="TSP1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036383">
        <property type="entry name" value="TSP1_rpt_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11857">
        <property type="entry name" value="DUF3377"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00090">
        <property type="entry name" value="TSP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00209">
        <property type="entry name" value="TSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82895">
        <property type="entry name" value="TSP-1 type 1 repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50092">
        <property type="entry name" value="TSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="298"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M10A matrix metallopeptidase C-terminal" evidence="4">
        <location>
            <begin position="293"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF11857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="340" mass="39917" checksum="31B6117D530B513B" modified="2017-02-15" version="1">MLKFFFYNLFYIFLYYKGIISDNFKLRNNENFIELLQKNGNYKIEILEPECTSESNVSSDQIKESYNFDRKEFLMHDFVVVKNSQFSNDTALELYHLKEKKKTSYLVLTFYIGDFKFPEGDSYEANLILNVVPVSTKNTCKHNTYIVSLLKTIDVNNPSEFEISKGPLKITISKTSGSFRINVTNFFKDDKWRAFSKNKISFLLKPEDYCYTKLENKLNKPSLIVEKKTIFYTEWGEWSSCSMTCDHPDNVQIRERQCIRENDDCFQGDLKESKMCEAILPKCSDTISKSNGFSTLKIILIILPLLLIICILLILYHIFYRKKGAEKELYENVAGRFMYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYY7</accession>
    <name>A0A1J1GYY7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dynein light chain, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00374500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529325.1">
        <property type="nucleotide sequence ID" value="XM_028672809.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYY7"/>
    <dbReference type="GeneID" id="39732275"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00374500"/>
    <dbReference type="OMA" id="SDFFFKE"/>
    <dbReference type="OrthoDB" id="10260741at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21451">
        <property type="entry name" value="DLC-like_TCTEX1D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.40">
        <property type="entry name" value="Tctex-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005334">
        <property type="entry name" value="Tctex-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038586">
        <property type="entry name" value="Tctex-1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21255:SF7">
        <property type="entry name" value="DYNEIN LIGHT CHAIN TCTEX-TYPE PROTEIN 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21255">
        <property type="entry name" value="T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03645">
        <property type="entry name" value="Tctex-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="102" mass="12174" checksum="DC1359F99761579D" modified="2017-02-15" version="1">MKEEIINSLKTLMKNELKNHLNNYINKKEISYHISNLIKSHIKSLTSNNYKIIVEILLNENNEQGINISTRLFYNKQSDFFFKERIINDTCHCFIVVYLIHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ10</accession>
    <name>A0A1J1GZ10_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Magnesium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00346900</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Mitochondrion inner membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529056.1">
        <property type="nucleotide sequence ID" value="XM_028672511.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ10"/>
    <dbReference type="GeneID" id="39731999"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00346900"/>
    <dbReference type="OMA" id="LVRKNMI"/>
    <dbReference type="OrthoDB" id="10251508at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12823">
        <property type="entry name" value="Mrs2_Mfm1p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039204">
        <property type="entry name" value="MRS2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13890:SF0">
        <property type="entry name" value="MAGNESIUM TRANSPORTER MRS2 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13890">
        <property type="entry name" value="RNA SPLICING PROTEIN MRS2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22099">
        <property type="entry name" value="MRS2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="344"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="381"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="208"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG96251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="417" mass="50096" checksum="0B7033FA9F8694DA" modified="2017-02-15" version="1">MIEWRYMKKYKNKIIHSIYLTSKTYIPVRFSSKYINVKNENKIYSKKNFNNILMQNIKITDEKIICEKVYFSKYNLPYVLKIPFSDLRLIDTYNNNHNPTILVRKNVILLRTGFISCIIRFNELWLFDPNNPLVIKAINLIKENFKKKCNLKIEECTDDVKNDDNSEDKRNDEKEDINDLNVKNNFYRYNTNNFFEFLCLDICMQLSLKEYENDIDQINGKIREKIQLQRREENNEINMLTNKLLRDMMKIKNNLQKLSNLLNALRSNIEKILKDDNDMKNMYLTFLHNNYINQLKDHSDLEILLETHLQLTDELYGELENIEEKITHYEELMRLNLDYNRNKFILLNAKISFSTLFCSICSVITSLFGMNLKNFIENNDYAFFIVSIFISGWSIIGIYFTKNINMLLKFFDKYKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ22</accession>
    <name>A0A1J1GZ22_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mediator of RNA polymerase II transcription subunit 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00027000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530635.1">
        <property type="nucleotide sequence ID" value="XM_028674264.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ22"/>
    <dbReference type="GeneID" id="39728793"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00027000"/>
    <dbReference type="OMA" id="QQECFRK"/>
    <dbReference type="OrthoDB" id="370430at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="126" mass="15043" checksum="5057BD48E26B63F8" modified="2017-02-15" version="1">MNENHMSSLKRLKEISKMIEATLHQNNRLKNILASELYFRKKCEASLELIDNTTNEQECYRKVSKIFIKKPRDSLKKELKEEIGEYEKHTPHLVELRKKLVDKLSNLKEQFVQTHECIEKETNRNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZA4</accession>
    <name>A0A1J1GZA4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00356500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529152.1">
        <property type="nucleotide sequence ID" value="XM_028672617.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZA4"/>
    <dbReference type="GeneID" id="39732095"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00356500"/>
    <dbReference type="OMA" id="STRQCWF"/>
    <dbReference type="OrthoDB" id="376860at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="180" mass="21779" checksum="5205F67B14743AB7" modified="2017-02-15" version="1">MSNNLKNCINYDFNQKVKWNFYINLRDVTDLKELDELLSEEDNCYTKMNNENKIKNINNICEKNLLGEIIKAYIFCKSVKIKETCNLCLMSWISTRQCWFDCDELLLNKYFEGLLEPLIFICKVLKEKVIYHFYQIPKELYIVFINKFKKYLRIYKDKEIILSIISSAWDIFYSKIYSQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZC1</accession>
    <name>A0A1J1GZC1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Myosin-A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">MyoB</name>
        <name evidence="11" type="ORF">PGAL8A_00024900</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530614.1">
        <property type="nucleotide sequence ID" value="XM_028674241.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZC1"/>
    <dbReference type="GeneID" id="39728772"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00024900"/>
    <dbReference type="OMA" id="SSCIEIF"/>
    <dbReference type="OrthoDB" id="312459at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016459">
        <property type="term" value="C:myosin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000146">
        <property type="term" value="F:microfilament motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007015">
        <property type="term" value="P:actin filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.820:FF:000001">
        <property type="entry name" value="Myosin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.4820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.720">
        <property type="entry name" value="Myosin VI head, motor domain, U50 subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001609">
        <property type="entry name" value="Myosin_head_motor_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140">
        <property type="entry name" value="MYOSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13140:SF270">
        <property type="entry name" value="MYOSIN-12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00063">
        <property type="entry name" value="Myosin_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00193">
        <property type="entry name" value="MYOSINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00242">
        <property type="entry name" value="MYSc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51456">
        <property type="entry name" value="MYOSIN_MOTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9" id="KW-0505">Motor protein</keyword>
    <keyword evidence="4 9" id="KW-0518">Myosin</keyword>
    <keyword evidence="2 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myosin motor" evidence="10">
        <location>
            <begin position="86"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="region of interest" description="Actin-binding" evidence="9">
        <location>
            <begin position="628"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="175"/>
            <end position="182"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00056291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00068456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG97814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="798" mass="93307" checksum="1EDA9B5562511B3A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZW9</accession>
    <name>A0A1J1GZW9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00043500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530801.1">
        <property type="nucleotide sequence ID" value="XM_028674450.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZW9"/>
    <dbReference type="GeneID" id="39728960"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00043500"/>
    <dbReference type="OMA" id="HILYIFP"/>
    <dbReference type="OrthoDB" id="381830at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="688" mass="83571" checksum="2AB9263027286CDE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZY9</accession>
    <name>A0A1J1GZY9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcription factor, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00057900</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530941.1">
        <property type="nucleotide sequence ID" value="XM_028674605.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZY9"/>
    <dbReference type="GeneID" id="39729104"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00057900"/>
    <dbReference type="OMA" id="PVLCENT"/>
    <dbReference type="OrthoDB" id="10056816at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10507">
        <property type="entry name" value="Zn-ribbon_RPA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034004">
        <property type="entry name" value="Zn_ribbon_RPA12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001222">
        <property type="entry name" value="Znf_TFIIS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01096">
        <property type="entry name" value="Zn_ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00440">
        <property type="entry name" value="ZnF_C2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51133">
        <property type="entry name" value="ZF_TFIIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIS-type" evidence="6">
        <location>
            <begin position="197"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG98144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="240" mass="29083" checksum="EF797E0053D9BB22" modified="2017-02-15" version="1" fragment="single">KEKNKEKYKIEKQNKDKEKKKVRFKQEEITYETILNYFIESFNNEINIEHDELCQILTGKKFYDIERLAKNATEITHYSIMSKNIQKEKESFCKNCGYTYNYDDYTFMYMKIFNLLKMGEKEFAFDSIRCIYCGTKIDDIELQNNFNDNENYIELHSYREKYIFDKNKKKYWKNKITSFDKNTSLFKEEKNKTYNITYEKCTDCGNDFLHFINIQTRSADEGSTIIYFCPNCKKQTTVNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZZ4</accession>
    <name>A0A1J1GZZ4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Chloroquine resistance transporter, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">CRT</name>
        <name evidence="11" type="ORF">PGAL8A_00049200</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CRT-like transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530854.1">
        <property type="nucleotide sequence ID" value="XM_028674508.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZZ4"/>
    <dbReference type="GeneID" id="39729017"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00049200"/>
    <dbReference type="OMA" id="FAYIIPM"/>
    <dbReference type="OrthoDB" id="416555at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013936">
        <property type="entry name" value="CRT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017258">
        <property type="entry name" value="Transprt_Chloroquine"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31326">
        <property type="entry name" value="PROTEIN CLT2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31326:SF1">
        <property type="entry name" value="PROTEIN CLT2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08627">
        <property type="entry name" value="CRT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037671">
        <property type="entry name" value="Transprt_Chloroquine_res"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="181"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="342"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="373"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG98057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="424" mass="49413" checksum="61D04789F1816CFA" modified="2017-02-15" version="1">MTVNTKNSQNNLSKMDEHYKELDTLLEDRNEIQRNRISFLRTLINWGKFIFYEIKSNIFIYLLSLLYLSVCVMNKVFAKRTMNKIGNYSFVTSEIHNTICIFVLFLVYFFFSNYNNNSKKRRKEPIFYYLFISLLDASTVIISFIGLTKTTGNIQSFALQLSIPINMFFCFLILRYRYHLFNYLGAFIIVATIAIVEMKMSMEIQEENSIIFNLIFISALIPLCFSNMTREIVFKKYKINILKLNAMISLFQLFTSCLILPVYTLPFLKQLQLPFSEILINIKNGFSCLFLGKNTIIENCGPGMTKMCDDCEGAWKTFITYSFFNICDNLVSSYIIDKFSTMTYTIVSCIQGPAIAIAYYFKFIAGDVMRKPRILDFVTLFGYLLGSIVYRAGNIILERKKIREDNYEENSDEQMTDEESVLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZZ5</accession>
    <name>A0A1J1GZZ5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cilia- and flagella-associated protein 299</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00444700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May be involved in spermatogenesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529669.1">
        <property type="nucleotide sequence ID" value="XM_028673191.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZZ5"/>
    <dbReference type="GeneID" id="39732980"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00444700"/>
    <dbReference type="OrthoDB" id="2136125at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027887">
        <property type="entry name" value="DUF4464"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33588">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33588:SF1">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14713">
        <property type="entry name" value="DUF4464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="249" mass="30008" checksum="C3E71FEF2F82725C" modified="2017-02-15" version="1">MQENRDNVITLESYEEYIKKKITPTDLFYIEDEELLFEIFTLGLKSRGILSKEDFNSTYKKKKKNEKITVKEENKENIIWDINILYNSTNDFFYIINYHIHFCKENRISTILFIRYLNKSKSEISSYIDINNNKVIEKIKNKKYIYASKKDLSYYNWKNNYISTNSNENYEIIINKKIGLIFKHKNSEKYFMLNSSKDLKIKLCDNIYKDNINTYFGENEEIIKLCDDIKKTEIKDSNYLQCLLYTLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H041</accession>
    <name>A0A1J1H041_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Selenide water dikinase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00423200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529456.1">
        <property type="nucleotide sequence ID" value="XM_028672955.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H041"/>
    <dbReference type="GeneID" id="39732764"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00423200"/>
    <dbReference type="OrthoDB" id="409395at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004756">
        <property type="term" value="F:selenide, water dikinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016260">
        <property type="term" value="P:selenocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="entry name" value="PurM-like C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="entry name" value="PurM-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004536">
        <property type="entry name" value="SPS/SelD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10256:SF0">
        <property type="entry name" value="INACTIVE SELENIDE, WATER DIKINASE-LIKE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10256">
        <property type="entry name" value="SELENIDE, WATER DIKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="PurM C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="PurM N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0711">Selenium</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="488"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="PurM-like N-terminal" evidence="8">
        <location>
            <begin position="667"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="domain" description="PurM-like C-terminal" evidence="9">
        <location>
            <begin position="842"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="785"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="785"/>
            <end position="800"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG96652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1088" mass="127711" checksum="4B46C08160828D02" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H049</accession>
    <name>A0A1J1H049_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Rhomboid protease ROM9, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ROM9</name>
        <name evidence="7" type="ORF">PGAL8A_00036600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530728.1">
        <property type="nucleotide sequence ID" value="XM_028674368.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H049"/>
    <dbReference type="GeneID" id="39728890"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00036600"/>
    <dbReference type="OMA" id="TYTLMFP"/>
    <dbReference type="OrthoDB" id="418595at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050925">
        <property type="entry name" value="Rhomboid_protease_S54"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43731">
        <property type="entry name" value="RHOMBOID PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43731:SF26">
        <property type="entry name" value="RHOMBOID-LIKE PROTEIN 10, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="189"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="248"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="287"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="338"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="370"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S54 rhomboid" evidence="6">
        <location>
            <begin position="246"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="396" mass="47521" checksum="9DD724377D61DE47" modified="2017-02-15" version="1">MKKKNLLEVKLIRNFHSRINYSKEIKHVLLEKNKYYLKCEKKSKFLNSNIIREFSRYSNKGKDEKGRNILLLIKKESMKNYITNLNNKIQSIIIKERNIQKFINKLYYKLHIKYMFLKNKYQNEISKYKNISSNISMIHLIKNDKKIKQLLNKLLIQKKYILNNIYYYYKNFNKSYYKSLILHHYNKSPITYSLMILHFLVFLLWLKSKPANSYDYFRKQYLSSYRLTSDFMYKYFCCSLQSLKEKKLFTLITSLISHNTIQSFLLNTISLYYIGTALEMLINSRNFIITYIMSGIISTYIQLLYHKNNYNNIYVFGASGSISSILMTYTFLYPKQNIYLYGIIALPLALFSGLYFLNEFYCVLTGKEDNTGHIAHLTGMGLGILYYYYIKRRMFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0A2</accession>
    <name>A0A1J1H0A2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ag-1 blood stage membrane protein homologue, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00055900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530921.1">
        <property type="nucleotide sequence ID" value="XM_028674583.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0A2"/>
    <dbReference type="GeneID" id="39729084"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00055900"/>
    <dbReference type="OrthoDB" id="359169at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053336">
        <property type="entry name" value="Rhoptry_Surface_Assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37320">
        <property type="entry name" value="AG-1 BLOOD STAGE MEMBRANE PROTEIN HOMOLOGUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37320:SF1">
        <property type="entry name" value="RHOPTRY SURFACE PROTEIN CERLI2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG98124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="454" mass="54374" checksum="A55ED475EC5C2289" modified="2017-02-15" version="1">MLGTNFILNFFKNKFNDLSKKCLTCVIRSYKRACPHISDFEPFASMYYFSGLHNYRTFYLLIRITEIFNINKYKKIYIIFSTDKYDFKTNEIATNKKNRIYTDQRIDIKIRQCDETLNVNLFTTKLTKKIHIGEIKIDINSNIVMKSFPKNQWFVCFKDGQEICKVQMSFYKIQKYACPNECMMIQDGLEMWKNSSKNLNKNNYKKINFQDIHKNFDDDDENLSIIDIDTDINDISLMQKLRLISFVLEQEIFVFDFYAYVPKYMSAKEIMGEWFLCFLCFKNSKEDETINIETIIERNIHRDINIPLFSIHRIVIDNKDNTNASIIYSYEDVKYNLCIHSKKHLSYIIDAITLFTNELRILKESYGEKLELRKNRIMQETNMRKLIGKRRVSSPRFRRSLPKSTNKMINEMYLEKSNSTEIKEKKEEFVNVKIIENNNKNEVENNRESCNYEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H115</accession>
    <name>A0A1J1H115_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein CINCH</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00058400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530946.1">
        <property type="nucleotide sequence ID" value="XM_028674611.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729109"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00058400"/>
    <dbReference type="OrthoDB" id="377737at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="267"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1318"/>
            <end position="1355"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="454"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="271"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1334"/>
            <end position="1355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1355" mass="161168" checksum="D24BCBFE9B4B514E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H203</accession>
    <name>A0A1J1H203_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Apicoplast ribosomal protein L27, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00493700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530160.1">
        <property type="nucleotide sequence ID" value="XM_028673737.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H203"/>
    <dbReference type="GeneID" id="39733470"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00493700"/>
    <dbReference type="OMA" id="DPKPMTY"/>
    <dbReference type="OrthoDB" id="1867012at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005762">
        <property type="term" value="C:mitochondrial large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000060">
        <property type="entry name" value="Apicoplast ribosomal protein L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001684">
        <property type="entry name" value="Ribosomal_bL27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018261">
        <property type="entry name" value="Ribosomal_bL27_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL27M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893">
        <property type="entry name" value="RIBOSOMAL PROTEIN L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01016">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00063">
        <property type="entry name" value="RIBOSOMALL27"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110324">
        <property type="entry name" value="Ribosomal L27 protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00831">
        <property type="entry name" value="RIBOSOMAL_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012023507" evidence="4">
        <location>
            <begin position="19"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="210" mass="24392" checksum="3D87064A8EB857D0" modified="2017-02-15" version="1">MKIHFLFIFLTLIKYVINSKIKSNIGNSGIYLGYIRKDSNLKLIPKKKYSYINNLCFFKRRNSEIYKIFKCNLFISTNYLKKFFIKNSYGKMKIIKFRNFNKLWAKKKGVGSTKNGRDSNPKNLGVKILGNNFAYPGNIIVRQRGRTFKPGYGVKQGRDFTLVATRAGKVNFFKGVVSIIDVNEPKKMTFKDIYQENPTILSLSKMWTST</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H236</accession>
    <name>A0A1J1H236_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Leucine-rich repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00496900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530192.1">
        <property type="nucleotide sequence ID" value="XM_028673773.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H236"/>
    <dbReference type="GeneID" id="39733502"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00496900"/>
    <dbReference type="OMA" id="IFHFMSK"/>
    <dbReference type="OrthoDB" id="341587at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="101"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="353" mass="41237" checksum="27C09457F9D7B8D8" modified="2017-02-15" version="1">MGKENSNKTNENYKNFVDCYYLLLRKFKKKSSYIIDEFLIKENKDSNGVLTIYEDINIDSFYFLILSMIDSNYDKINILNVQNGNNIIRAICFYMDNIKINELLKKNTKNIRNKNSNLEKNNNNNNNKIKIKKKDIEEEKNIDINKKSQCNINSLSIFNSNVDINGIILLSKSLYDNNYSKIENLSIDCNPLTFDCVKYLSFSLCNYNNLKNLSFQYCNLKNDSIKYIIDIIIYLNSSLRTLNLSGNNFTSEGMSKLFESFLLNHSLTNVDVSYNMFNLDNLFTEIFCKLIISETSISNITLIGNFIEENNLSKINEAMNYNKSISILKLPQELICKKKEKTFFFLIFHFMSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2A8</accession>
    <name>A0A1J1H2A8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">carbamoyl-phosphate synthase (ammonia)</fullName>
            <ecNumber evidence="5">6.3.4.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00504300</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>hydrogencarbonate + NH4(+) + 2 ATP = carbamoyl phosphate + 2 ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:18029"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.16"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.16" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530271.1">
        <property type="nucleotide sequence ID" value="XM_028673860.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733576"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00504300"/>
    <dbReference type="OMA" id="WSPFNGK"/>
    <dbReference type="OrthoDB" id="1924069at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005951">
        <property type="term" value="C:carbamoyl-phosphate synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004087">
        <property type="term" value="F:carbamoyl-phosphate synthase (ammonia) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:L-arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01744">
        <property type="entry name" value="GATase1_CPSase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01423">
        <property type="entry name" value="MGS_CPS_I_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000051">
        <property type="entry name" value="Carbamoyl phosphate synthetase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.20:FF:000019">
        <property type="entry name" value="Carbamoyl phosphate synthetase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.20:FF:000001">
        <property type="entry name" value="Carbamoyl-phosphate synthase large chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000001">
        <property type="entry name" value="Carbamoyl-phosphate synthase large chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.20:FF:000002">
        <property type="entry name" value="Carbamoyl-phosphate synthase large chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1030.10:FF:000003">
        <property type="entry name" value="Carbamoyl-phosphate synthase, large subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.20">
        <property type="entry name" value="Carbamoyl-phosphate synthase small subunit, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1030.10">
        <property type="entry name" value="Carbamoyl-phosphate synthetase, large subunit oligomerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="entry name" value="Methylglyoxal synthase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01209">
        <property type="entry name" value="CPSase_S_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036897">
        <property type="entry name" value="CarbamoylP_synth_lsu_oligo_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006274">
        <property type="entry name" value="CarbamoylP_synth_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002474">
        <property type="entry name" value="CarbamoylP_synth_ssu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036480">
        <property type="entry name" value="CarbP_synth_ssu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005483">
        <property type="entry name" value="CPSase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035686">
        <property type="entry name" value="CPSase_GATase1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005480">
        <property type="entry name" value="CPSase_lsu_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058047">
        <property type="entry name" value="CPSase_preATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003671">
        <property type="entry name" value="PRK05294.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405:SF5">
        <property type="entry name" value="CAD PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405">
        <property type="entry name" value="CARBAMOYLTRANSFERASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25596">
        <property type="entry name" value="CPSase_L_D1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02787">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00988">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02142">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00098">
        <property type="entry name" value="CPSASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00099">
        <property type="entry name" value="CPSGATASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00096">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01096">
        <property type="entry name" value="CPSase_L_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01097">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00851">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48108">
        <property type="entry name" value="Carbamoyl phosphate synthetase, large subunit connection domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52021">
        <property type="entry name" value="Carbamoyl phosphate synthetase, small subunit N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="Methylglyoxal synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ATP-grasp" evidence="9">
        <location>
            <begin position="771"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="9">
        <location>
            <begin position="1749"/>
            <end position="1940"/>
        </location>
    </feature>
    <feature type="domain" description="MGS-like" evidence="10">
        <location>
            <begin position="2006"/>
            <end position="2165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1205"/>
            <end position="1237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1360"/>
            <end position="1381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1531"/>
            <end position="1586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1223"/>
            <end position="1237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1360"/>
            <end position="1372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1535"/>
            <end position="1545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00044063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG97470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2165" mass="249083" checksum="06C097CD9DE07E56" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2D9</accession>
    <name>A0A1J1H2D9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00524300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530468.1">
        <property type="nucleotide sequence ID" value="XM_028674079.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2D9"/>
    <dbReference type="GeneID" id="39733776"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00524300"/>
    <dbReference type="OrthoDB" id="391553at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="469" mass="57331" checksum="AB11DBB3A351C70D" modified="2017-02-15" version="1">MITKKFHKIRKGYLNCYRNISNNGKISYKDKNLNLCVSFNNNANVNHERFDNKFYLYNINSTIFKLFKYIHIFRKKYKKDTDLNNKMKDKYKIEQIFMCYISIYKNINRNLFLKLTLEILKFSILNKKIINDNEFYEELLKEVIGCRKEKELEKTIFYEYLIKILSILLMNSNFFNENFHRIFFIEALEMMKKEENINSFMKNFTYILSCISFYNRILKKELYGNTSVLLNIPSNNQIFLNQLKKNTLVNSLSIILDIFDRIQNYNYFNEVDICNIFDFLNEFKKTHNIKTIIYKNIHKYFTTLSQMKNLCLFLYLISTCTNAIHQNIYIYIYNIIFLKRKELTDLKNINLFLLSIIKYKNEKSNLDINKIKRNNLIKKRNLKKIKNINKKFELCLKLKHGYIKKRKRNDEKVIYFFIKHQFIQLIKKKKMSAKHVKTFYQYFLFYHIKKNFTRKKNYVSPINIINNYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2P2</accession>
    <name>A0A1J1H2P2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DnaJ protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00518700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530415.1">
        <property type="nucleotide sequence ID" value="XM_028674020.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2P2"/>
    <dbReference type="GeneID" id="39733720"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00518700"/>
    <dbReference type="OMA" id="ENRGIHN"/>
    <dbReference type="OrthoDB" id="10461005at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="1">
        <location>
            <begin position="8"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="496" mass="59420" checksum="70048B2C4024A324" modified="2017-02-15" version="1">MGKDNATKAFKYFNLSLNCSEKELKKNYFNKIKNLHPDKHLYKNISIQKKYSNEFLEAHRQFQIAISFLKKKRNEKDKLKYDQEDNPFNNLNKNNRQSYSSTISSSNFFFKNIKLTKVLFYLKKSYFLFSIPFIIYFIENIIDTKNCKNTNDKEDYNFTIKINKENNKRQDSNILRNELCKSHIGNVYNEKKDALSLFKLRYIFNVVKIRKAEKKPNANYINRNIFEEEKNDLNYLKKQILFQNKMEDINIFKDSKFLNHNKMFFDDLLENKKISMNLVAHPKNVLQNFIIFSKEISNKNSFNYNIISFSNFKKNSMKKEDKVKKIKHKNSFLKKNIDNNPLYKNFLLSENRGIHNESRYINGIGGLCGGYNLIKGENEQINEEGIIKKEKFLSKDMIYMNEIRNNELIDDLINLQNSIIYEKSKYINFSNPLKYIKYRRGNKINLNNYFKCRNCKINLKDTNFRNNIKKHTFNNLNNQTEDKNFNLSHSLDKKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H353</accession>
    <name>A0A1J1H353_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ras-related protein Rab-1A, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RAB1a</name>
        <name evidence="3" type="ORF">PGAL8A_00035300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530716.1">
        <property type="nucleotide sequence ID" value="XM_028674355.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H353"/>
    <dbReference type="GeneID" id="39728877"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00035300"/>
    <dbReference type="OMA" id="HEIDTNC"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001929">
        <property type="entry name" value="Ras-related protein Rab-1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050227">
        <property type="entry name" value="Rab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47977">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="206" mass="23720" checksum="5F3132D6E34E91DF" modified="2017-02-15" version="1">MSENRSRDYDYLYKIILIGDSGVGKSCILLRFSDDHFTESYITTIGVDFRFRTIKVDEKIVKLQIWDTAGQERFRTITSAYYRGADGIIIIYDTTDRNSFLHIDEWMNEINKYTNEDTCKLLVGNKADCREEIEITTNEGENKAKELDIPFIETSAKDATNVELAFTMITQELIKKKKKNSNSNKNNQTKVKLSAEERAQGSFCSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3D1</accession>
    <name>A0A1J1H3D1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Centrin, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00043000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG97999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530796.1">
        <property type="nucleotide sequence ID" value="XM_028674445.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3D1"/>
    <dbReference type="GeneID" id="39728955"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00043000"/>
    <dbReference type="OMA" id="NEYMIFI"/>
    <dbReference type="OrthoDB" id="10263155at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013312131" evidence="2">
        <location>
            <begin position="24"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="41"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="77"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="105" mass="12550" checksum="ED089271A84F61BF" modified="2017-02-15" version="1">MKLSFQLFFLFFFFLIFWNKLKSESKYNDEVNKTNDGISEEEKEEVYLEFAEYDLNRDGLIDAEEITLVLKNMKKSDFVNFFIKVDLDSSGTISFDEYMIFIESN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3F9</accession>
    <name>A0A1J1H3F9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Purine nucleoside phosphorylase, putative</fullName>
            <ecNumber evidence="2">2.4.2.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00031500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.1" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530679.1">
        <property type="nucleotide sequence ID" value="XM_028674314.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3F9"/>
    <dbReference type="GeneID" id="39728838"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00031500"/>
    <dbReference type="OMA" id="AQNREYK"/>
    <dbReference type="OrthoDB" id="416752at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004731">
        <property type="term" value="F:purine-nucleoside phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004850">
        <property type="term" value="F:uridine phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006218">
        <property type="term" value="P:uridine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17767">
        <property type="entry name" value="UP_EcUdp-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="entry name" value="Nucleoside phosphorylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43691:SF11">
        <property type="entry name" value="FI09636P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43691">
        <property type="entry name" value="URIDINE PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="Purine and uridine phosphorylases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleoside phosphorylase" evidence="1">
        <location>
            <begin position="18"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="245" mass="27287" checksum="6EE5F69B27980FE8" modified="2017-02-15" version="1">MEEVERHIKLSKKNYCSVALIVGDPERVDKVKLLCDSYVDLAYHREYKSAECHYKGQKFLCVSHGVGSAGCAICVEELINIGVKVLIRAGSCGTLQPHEMKRGDICVCHAAIREDRLSHLIINADFPAVADFEVYDTLLKCANELNEHIFTGMCLTSDLYYKHSLIPNQLELYSKAHVAINDMELATVMVIGSLKKVKVGGIFIVDGSPLKWDEGNFDPVLNPEKLKNMIIISLNACARLAAKYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2012-05-16" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>H7CDW9</accession>
    <name>H7CDW9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Large subunit ribosomal protein 23</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Ribosomal protein L23, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpl23</name>
        <name evidence="2" type="synonym">RPL23</name>
        <name evidence="2" type="ORF">PGAL8A_API01300</name>
    </gene>
    <organism evidence="1">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <geneLocation type="apicoplast" evidence="1"/>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2012" name="Mol. Biol. Evol." volume="29" first="2095" last="2099">
            <title>The Plasmodium Apicoplast Genome: Conserved Structure and Close Relationship of P. ovale to Rodent Malaria Parasites.</title>
            <authorList>
                <person name="Arisue N."/>
                <person name="Hashimoto T."/>
                <person name="Mitsui H."/>
                <person name="Palacpac N.M.Q."/>
                <person name="Kaneko A."/>
                <person name="Kawai S."/>
                <person name="Hasegawa M."/>
                <person name="Tanabe K."/>
                <person name="Horii T."/>
            </authorList>
            <dbReference type="PubMed" id="22396524"/>
            <dbReference type="DOI" id="10.1093/molbev/mss082"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">A8</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">8A</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AB649424">
        <property type="protein sequence ID" value="BAL70739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LN835293">
        <property type="protein sequence ID" value="CRG98228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009325455.1">
        <property type="nucleotide sequence ID" value="NC_031963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="H7CDW9"/>
    <dbReference type="GeneID" id="30315800"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_API01300"/>
    <dbReference type="OrthoDB" id="372952at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Apicoplast API"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0933">Apicoplast</keyword>
    <keyword evidence="1" id="KW-0934">Plastid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAL70739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="69" mass="8671" checksum="CAF0C9F9CF546558" modified="2012-05-16" version="1">MKEIILNLYLNNIFYKVNFINKFIIIYTNKYLTKLDIKYILKYIFNKKFIKINNINNNKVFKKYYISFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2015-01-07" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A097F754</accession>
    <name>A0A097F754_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9 10">Apical membrane antigen 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ama-1</name>
        <name evidence="10" type="synonym">AMA1</name>
        <name evidence="10" type="ORF">PGAL8A_00360900</name>
    </gene>
    <organism evidence="9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2014" name="Malar. J." volume="13" first="382" last="382">
            <title>Transcriptome sequencing and analysis of Plasmodium gallinaceum reveals polymorphisms and selection on the apical membrane antigen-1.</title>
            <authorList>
                <person name="Lauron E.J."/>
                <person name="Oakgrove K.S."/>
                <person name="Tell L.A."/>
                <person name="Biskar K."/>
                <person name="Roy S.W."/>
                <person name="Sehgal R.N."/>
            </authorList>
            <dbReference type="PubMed" id="25261185"/>
            <dbReference type="DOI" id="10.1186/1475-2875-13-382"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="10 11" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the apicomplexan parasites AMA1 family.</text>
    </comment>
    <dbReference type="EMBL" id="KJ722597">
        <property type="protein sequence ID" value="AIT18314.1"/>
        <property type="molecule type" value="mRNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A097F754"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00360900"/>
    <dbReference type="OMA" id="KDEMLDP"/>
    <dbReference type="OrthoDB" id="345315at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1010.10">
        <property type="entry name" value="Apical membrane antigen 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003298">
        <property type="entry name" value="Apmem_Ag1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024056">
        <property type="entry name" value="Apmem_Ag1_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02430">
        <property type="entry name" value="AMA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01361">
        <property type="entry name" value="MEROZOITESA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00815">
        <property type="entry name" value="AMA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82910">
        <property type="entry name" value="Apical membrane antigen 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="479"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AIT18314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG96385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="556" mass="63626" checksum="4F4C7B46E41775FC" modified="2015-01-07" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKS6</accession>
    <name>A0A1J1GKS6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Karyopherin beta, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00071200</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525830.1">
        <property type="nucleotide sequence ID" value="XM_028674712.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKS6"/>
    <dbReference type="GeneID" id="39729237"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00071200"/>
    <dbReference type="OMA" id="GRAMECG"/>
    <dbReference type="OrthoDB" id="543373at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058584">
        <property type="entry name" value="IMB1_TNPO1-like_TPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040122">
        <property type="entry name" value="Importin_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041653">
        <property type="entry name" value="Importin_rep_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041389">
        <property type="entry name" value="Importin_rep_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034085">
        <property type="entry name" value="TOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057672">
        <property type="entry name" value="TPR_IPO4/5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10527">
        <property type="entry name" value="IMPORTIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18808">
        <property type="entry name" value="Importin_rep_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18829">
        <property type="entry name" value="Importin_rep_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25574">
        <property type="entry name" value="TPR_IMB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25780">
        <property type="entry name" value="TPR_IPO5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12755">
        <property type="entry name" value="Vac14_Fab1_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01349">
        <property type="entry name" value="TOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="TOG" evidence="8">
        <location>
            <begin position="418"/>
            <end position="665"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1123" mass="127467" checksum="947BB3B9341E1DA1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKT3</accession>
    <name>A0A1J1GKT3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ubiquitin fusion degradation protein UFD1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00072000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UFD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525838.1">
        <property type="nucleotide sequence ID" value="XM_028674801.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKT3"/>
    <dbReference type="GeneID" id="39729245"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00072000"/>
    <dbReference type="OMA" id="LIFPTRH"/>
    <dbReference type="OrthoDB" id="422728at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034098">
        <property type="term" value="C:VCP-NPL4-UFD1 AAA ATPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.50">
        <property type="entry name" value="Ubiquitin fusion degradation protein UFD1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004854">
        <property type="entry name" value="Ufd1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042299">
        <property type="entry name" value="Ufd1-like_Nn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055417">
        <property type="entry name" value="UFD1_N1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055418">
        <property type="entry name" value="UFD1_N2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12555">
        <property type="entry name" value="UBIQUITIN FUSION DEGRADATON PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12555:SF13">
        <property type="entry name" value="UBIQUITIN RECOGNITION FACTOR IN ER-ASSOCIATED DEGRADATION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03152">
        <property type="entry name" value="UFD1_N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24842">
        <property type="entry name" value="UFD1_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin fusion degradation protein UFD1 N-terminal subdomain 1" evidence="3">
        <location>
            <begin position="63"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin fusion degradation protein UFD1 N-terminal subdomain 2" evidence="4">
        <location>
            <begin position="165"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF24842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="647" mass="76337" checksum="AA35161271D92C92" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKZ4</accession>
    <name>A0A1J1GKZ4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="6">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00074500</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525863.1">
        <property type="nucleotide sequence ID" value="XM_028675078.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKZ4"/>
    <dbReference type="GeneID" id="39729270"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00074500"/>
    <dbReference type="OMA" id="GRDWHIA"/>
    <dbReference type="OrthoDB" id="333239at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061136">
        <property type="term" value="P:regulation of proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16104">
        <property type="entry name" value="Ubl_USP14_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000119">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044635">
        <property type="entry name" value="UBP14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43982:SF1">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="3 6" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="8">
        <location>
            <begin position="4"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="9">
        <location>
            <begin position="110"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="386"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="402"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG93041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="584" mass="68786" checksum="AFA1DEE883E75F82" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLQ5</accession>
    <name>A0A1J1GLQ5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Chromatin assembly factor 1 protein WD40 domain, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00106500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526182.1">
        <property type="nucleotide sequence ID" value="XM_028673377.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLQ5"/>
    <dbReference type="GeneID" id="39729591"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00106500"/>
    <dbReference type="OMA" id="CDIRTNQ"/>
    <dbReference type="OrthoDB" id="427795at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022052">
        <property type="entry name" value="Histone-bd_RBBP4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050459">
        <property type="entry name" value="WD_repeat_RBAP46/RBAP48/MSI1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22850">
        <property type="entry name" value="WD40 REPEAT FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12265">
        <property type="entry name" value="CAF1C_H4-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Histone-binding protein RBBP4-like N-terminal" evidence="6">
        <location>
            <begin position="47"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="291"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="334"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="19"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="446" mass="50929" checksum="AB508C9737205841" modified="2017-02-15" version="1">MSSPKDNKKRKSNTLDEACIELSEEVENEEVTKEKEESEEEDIEVQFNNWKTNSGLLYDFVCRKELEWPSLSIDFGDFHDENIENNVLNQIVCVGTHTSNKEPNFLYVCDVLFPLEKVPQEKCVYKENENYEGFEFCTEKKKFTIKSKIAHTGEVNRIKFLPMEKKNFVVTKAVDGNLHLFDINKHKIETNDDKMSPEVSFIGNQSDGFGLDFNTHKKNILTCGNDGLINVYDYNDLSSNIVNPFYKVQYKSPINDISPTNDPNLILACADNGYILLYDLRIKTSEPAQQVLGQQVPVNSVSLNKFTGYFASGSDNGKIKIWDIKKFNEPQHIINAHQEAIIRLNFSPNDSSLLASASNNRFINVYDLNKIGEELDAIDLSDGPSELIFSHGGHTQSITDFNWNHHKKLKMFIGSTSEDNTLQFWQLKMELLDETNTVPTTDTDVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLT5</accession>
    <name>A0A1J1GLT5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acetyltransferase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00107900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the acetyltransferase family. MAK3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526196.1">
        <property type="nucleotide sequence ID" value="XM_028673533.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLT5"/>
    <dbReference type="GeneID" id="39729605"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00107900"/>
    <dbReference type="OrthoDB" id="249099at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031417">
        <property type="term" value="C:NatC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004596">
        <property type="term" value="F:protein-N-terminal amino-acid acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044542">
        <property type="entry name" value="NAA30-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45896">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45896:SF1">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="4">
        <location>
            <begin position="70"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="220" mass="25688" checksum="9C86B18AD92962AE" modified="2017-02-15" version="1">MNREITSVDESVNEKIENCGSSFFLNRTDIVLENTYDQSKENTHEQFNNTIKKSTIYQTVIFNKKKIEVYQFKEFPKKYLNSVYELLSEELSEPYSIFLLKTILKNYSEIALMSLYDEKCVGTVISKISSKYKNDDEPISFGYICMIAVHKSIKGCGSYLLNENIKLMQSLYGVNEVHLEAEATNNPTLRFYEKNGFIRVKRKPYYYLNGVDAFKLKKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLX3</accession>
    <name>A0A1J1GLX3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ras-related protein Rab-5C, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RAB5c</name>
        <name evidence="3" type="ORF">PGAL8A_00102900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526145.1">
        <property type="nucleotide sequence ID" value="XM_028672965.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLX3"/>
    <dbReference type="GeneID" id="39729554"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00102900"/>
    <dbReference type="OMA" id="TEWIPTI"/>
    <dbReference type="OrthoDB" id="63533at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000823">
        <property type="entry name" value="Small GTPase RAB, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47978">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="150" mass="16961" checksum="05CB5979D1CE4F5C" modified="2017-02-15" version="1">MTQLIDIGECTIKFEIWDTAGQERYRSLAPMYYRGASAAVIVYDITNKKSFEGAKGWINELKSVHSNDIIIALAGNKNDLEDSRVVDRELAESFANSNNILFIETSAKTGQNVNELFLRIAKKLPLNKKEQDKNSGIQINNTEETKRRCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM83</accession>
    <name>A0A1J1GM83_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cold-shock protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00105500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526171.1">
        <property type="nucleotide sequence ID" value="XM_028673254.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM83"/>
    <dbReference type="GeneID" id="39729580"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00105500"/>
    <dbReference type="OrthoDB" id="422005at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003730">
        <property type="term" value="F:mRNA 3'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043488">
        <property type="term" value="P:regulation of mRNA stability"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04458">
        <property type="entry name" value="CSP_CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052069">
        <property type="entry name" value="Ca-reg_mRNA-binding_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019844">
        <property type="entry name" value="CSD_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002059">
        <property type="entry name" value="CSP_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12962">
        <property type="entry name" value="CALCIUM-REGULATED HEAT STABLE PROTEIN CRHSP-24-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12962:SF1">
        <property type="entry name" value="COLD SHOCK DOMAIN-CONTAINING PROTEIN CG9705"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00313">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00352">
        <property type="entry name" value="CSD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51857">
        <property type="entry name" value="CSD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CSD" evidence="2">
        <location>
            <begin position="29"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="140" mass="16774" checksum="08B158B40176C0FC" modified="2017-02-15" version="1">MFKRKQSHTFLNFFKKFFFSEFINKENDKITGNVVKFDKRKGYGFIKPNDGGPDVFVHYSDICHNRSYAITSKEKNKLTWNSNMNLRNNKDDLNFENDYKKEQEIKKEFKYLIPGERVKFSVIYDEKSHSSKAINVEYLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMC4</accession>
    <name>A0A1J1GMC4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Asparagine-rich antigen, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00110200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526219.1">
        <property type="nucleotide sequence ID" value="XM_028673788.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729628"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00110200"/>
    <dbReference type="OrthoDB" id="372751at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="75"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="578"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="857"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1216"/>
            <end position="1272"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1298"/>
            <end position="1366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="857"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1216"/>
            <end position="1225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1233"/>
            <end position="1248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1260"/>
            <end position="1270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1920" mass="224539" checksum="0EFFD12DF6202BC8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMX8</accession>
    <name>A0A1J1GMX8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">EGF-like membrane protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00151800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526630.1">
        <property type="nucleotide sequence ID" value="XM_028675061.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMX8"/>
    <dbReference type="GeneID" id="39730042"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00151800"/>
    <dbReference type="OMA" id="FLCCCNV"/>
    <dbReference type="OrthoDB" id="5953235at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012453005" evidence="3">
        <location>
            <begin position="24"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="194"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="4">
        <location>
            <begin position="76"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="4">
        <location>
            <begin position="115"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="80"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="103"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="236" mass="27206" checksum="580B60D783FA3FB7" modified="2017-02-15" version="1">MIRHCYLIIKLLLFFYFLDKIHIFYCQNCDGQHNCKDKCLMLSDDKKVCLCNSNEKGIYCKAKWNVCENDCNILGIKESCSVALCKTGTCNPIETKPYYKCECGDFFKGKNCEIENNPCTFPETNPCLNGTCIFIAKLNRIICKCNNGWTQKNVQNSSLLNWGNQKVEVPPPCDEQIKRGLSKYVIYHTPASYAMWWLIYVISVLVLFLCCCNVCFDIFSNSMLSYFGGFNNRKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN16</accession>
    <name>A0A1J1GN16_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ankyrin-repeat protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00155600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526668.1">
        <property type="nucleotide sequence ID" value="XM_028675103.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730080"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00155600"/>
    <dbReference type="OMA" id="HLIYHKL"/>
    <dbReference type="OrthoDB" id="20872at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050889">
        <property type="entry name" value="Dendritic_Spine_Reg/Scaffold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24166:SF48">
        <property type="entry name" value="PROTEIN VAPYRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24166">
        <property type="entry name" value="ROLLING PEBBLES, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1142"/>
            <end position="1174"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1178"/>
            <end position="1206"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1313"/>
            <end position="1345"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1346"/>
            <end position="1378"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1415"/>
            <end position="1447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="47"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="412"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="614"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="722"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="47"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="412"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="620"/>
            <end position="630"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1534" mass="179115" checksum="3E94C58A804F1491" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNB9</accession>
    <name>A0A1J1GNB9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00164700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526759.1">
        <property type="nucleotide sequence ID" value="XM_028675204.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730172"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00164700"/>
    <dbReference type="OMA" id="ENHSDHD"/>
    <dbReference type="OrthoDB" id="392829at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1035"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="4"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="150"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="781"/>
            <end position="818"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1472" mass="178468" checksum="764D0DDE4E233CE6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNC7</accession>
    <name>A0A1J1GNC7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein DJ-1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">DJ1</name>
        <name evidence="3" type="ORF">PGAL8A_00156000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526673.1">
        <property type="nucleotide sequence ID" value="XM_028675108.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNC7"/>
    <dbReference type="GeneID" id="39730085"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00156000"/>
    <dbReference type="OMA" id="KATCYPG"/>
    <dbReference type="OrthoDB" id="543156at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903189">
        <property type="term" value="P:glyoxal metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03135">
        <property type="entry name" value="GATase1_DJ-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.880:FF:000015">
        <property type="entry name" value="Protein DJ-1 homolog C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006287">
        <property type="entry name" value="DJ-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050325">
        <property type="entry name" value="Prot/Nucl_acid_deglycase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01383">
        <property type="entry name" value="not_thiJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48094:SF12">
        <property type="entry name" value="PARKINSON DISEASE PROTEIN 7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48094">
        <property type="entry name" value="PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="DJ-1/PfpI" evidence="2">
        <location>
            <begin position="5"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="189" mass="20451" checksum="493BB7D768A82458" modified="2017-02-15" version="1">MSVKKTALVVVASGSEDVEYITVVDILRRANMDVTTASVEETEKVCLQSKNIVMADVTIAEISNLTFDVIVIPGGMKGSNAIANCEPFIKMLKEQKNSNRLYAAICAAPQTVLNRHSLIDDVEAVAYPSLDKDFKYVGNGRVCVSKNCITSVGPGSATEFALKIVEVLLGRDVAQKLAKDFILHPSIIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNQ1</accession>
    <name>A0A1J1GNQ1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">riboflavin kinase</fullName>
            <ecNumber evidence="2">2.7.1.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00165600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (ATP route): step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.26" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526769.1">
        <property type="nucleotide sequence ID" value="XM_028675215.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNQ1"/>
    <dbReference type="GeneID" id="39730182"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00165600"/>
    <dbReference type="OMA" id="SWRIFYI"/>
    <dbReference type="OrthoDB" id="276388at2759"/>
    <dbReference type="UniPathway" id="UPA00276">
        <property type="reaction ID" value="UER00406"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008531">
        <property type="term" value="F:riboflavin kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009398">
        <property type="term" value="P:FMN biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.30">
        <property type="entry name" value="Riboflavin kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023468">
        <property type="entry name" value="Riboflavin_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015865">
        <property type="entry name" value="Riboflavin_kinase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023465">
        <property type="entry name" value="Riboflavin_kinase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22749:SF6">
        <property type="entry name" value="RIBOFLAVIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22749">
        <property type="entry name" value="RIBOFLAVIN KINASE/FMN ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01687">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00904">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82114">
        <property type="entry name" value="Riboflavin kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0288">FMN</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Riboflavin kinase" evidence="8">
        <location>
            <begin position="454"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG93948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="599" mass="71525" checksum="1F5DF9D5EA060019" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP71</accession>
    <name>A0A1J1GP71_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ubiquitin-conjugating enzyme, putative</fullName>
            <ecNumber evidence="6">6.3.2.19</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00397000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.19" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527087.1">
        <property type="nucleotide sequence ID" value="XM_028670324.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP71"/>
    <dbReference type="GeneID" id="39732500"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00397000"/>
    <dbReference type="OMA" id="MMYCHAI"/>
    <dbReference type="OrthoDB" id="9984419at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd23790">
        <property type="entry name" value="UBCc_UBE2A_2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000054">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="5">
        <location>
            <begin position="4"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="3">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG94266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="160" mass="18507" checksum="68441A62B0120918" modified="2017-02-15" version="1">MSTFARRRIIQDLNKVNREQNKSFEASPFADNIMCCHAIIRGPQDTIWECGIFHLIINFSEEYPICPPKLKFLSKIFHPNIYTDGNICLDILQNQWSPIYDITSLLTSIQSLLNDPNTSSPANPEAARIFINNKTLYNKRVLMCVEDSWEIPKFNINNLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPD5</accession>
    <name>A0A1J1GPD5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 19">DNA-directed RNA polymerase subunit beta</fullName>
            <ecNumber evidence="5 19">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="28" type="primary">RPB2</name>
        <name evidence="28" type="ORF">PGAL8A_00406300</name>
    </gene>
    <organism evidence="28 29">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="28" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="28">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 19">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="16">In plastids the minimal PEP RNA polymerase catalytic core is composed of four subunits: alpha, beta, beta', and beta''. When a (nuclear-encoded) sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Plastid</location>
            <location evidence="3">Apicoplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 18">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="28">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="5 19"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527180.1">
        <property type="nucleotide sequence ID" value="XM_028670427.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732593"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00406300"/>
    <dbReference type="OMA" id="LQAQVYF"/>
    <dbReference type="OrthoDB" id="10248617at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020011">
        <property type="term" value="C:apicoplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.270.10:FF:000006">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.270.10:FF:000011">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1110.10:FF:000005">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1800.10:FF:000002">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1100.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="entry name" value="DNA-directed RNA polymerase, subunit 2, domain 6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1800.10">
        <property type="entry name" value="RNA polymerase alpha subunit dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007646">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007647">
        <property type="entry name" value="RNA_pol_Rpb2_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007175">
        <property type="entry name" value="PRK09606.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04566">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04567">
        <property type="entry name" value="RNA_pol_Rpb2_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0933">Apicoplast</keyword>
    <keyword evidence="7 19 28" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 19 28" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-0934">Plastid</keyword>
    <keyword evidence="29" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14 19" id="KW-0804">Transcription</keyword>
    <keyword evidence="9 19 28" id="KW-0808">Transferase</keyword>
    <keyword evidence="12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RNA polymerase beta subunit protrusion" evidence="24">
        <location>
            <begin position="47"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="23">
        <location>
            <begin position="218"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="25">
        <location>
            <begin position="485"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="26">
        <location>
            <begin position="585"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="27">
        <location>
            <begin position="672"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase subunit 2 hybrid-binding" evidence="21">
        <location>
            <begin position="725"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase subunit 2 hybrid-binding" evidence="21">
        <location>
            <begin position="991"/>
            <end position="1209"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="22">
        <location>
            <begin position="1211"/>
            <end position="1302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="911"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="911"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="956"/>
            <end position="970"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00026088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU363031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF04561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF04563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="Pfam" id="PF04566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="27">
        <source>
            <dbReference type="Pfam" id="PF04567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="EMBL" id="CRG94359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="29">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1305" mass="148086" checksum="8CE6864B69AC8EE7" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPG1</accession>
    <name>A0A1J1GPG1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RNA-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00087900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525997.1">
        <property type="nucleotide sequence ID" value="XM_028671322.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPG1"/>
    <dbReference type="GeneID" id="39729403"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00087900"/>
    <dbReference type="OMA" id="VIAQDHE"/>
    <dbReference type="OrthoDB" id="1875751at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48033">
        <property type="entry name" value="RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48033:SF10">
        <property type="entry name" value="RNA-BINDING PROTEIN SQUID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="117"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="201"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="23"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="360" mass="42077" checksum="5A78C659E798D8F7" modified="2017-02-15" version="1">MTIDDNINETNDADISLKTKVSKNNEAEKKKKDSDTQKNEYDNTCEQREKRDRSSSRDSFKPEKKKICCCHETNSAKCSKYEKNNSNTKNKNVDSLSTASTGINEFVNNSKNINEPFKFFIGGIPQNITNKDIIEYFEKYGTVQNVVIAQDHETKRNRGFAFVTMLSQINKERILRDAHELNGKRVDVREEHNTTPSDIQRKIFVGGLNYYWTKDTLENYFSTFGDIDVVQIVVDSSGRSRCFGFVVFANENSVAKVLKHKRHKIYDKMVEVRKAEPKKPKMAMKRQNTKTYPKYPHHIPFMTPFPCNKETMAQWANFMYNTCGVPFLFNQRFQNIPDFYPNYNYYPNSMENLQQSEYNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPG5</accession>
    <name>A0A1J1GPG5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SRR1-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00403400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SRR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527151.1">
        <property type="nucleotide sequence ID" value="XM_028670394.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPG5"/>
    <dbReference type="GeneID" id="39732564"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00403400"/>
    <dbReference type="OMA" id="HCDISLY"/>
    <dbReference type="OrthoDB" id="551431at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012942">
        <property type="entry name" value="SRR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040044">
        <property type="entry name" value="SRR1L"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28626">
        <property type="entry name" value="SRR1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28626:SF3">
        <property type="entry name" value="SRR1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07985">
        <property type="entry name" value="SRR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRR1-like" evidence="2">
        <location>
            <begin position="76"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="344" mass="41821" checksum="A0000607CDE9EA22" modified="2017-02-15" version="1">MENWVLVKNKYKLKKNKNKKIEELYINKEEEKYLTYNTENYKENLDSDKKHIERIYNEIKKVISSLEKSIFFINFQKKFNEINRNNINIGVICLGLGSLTDINSNNKKSCFYQLSFILLLKKIYKIDNIYIYDPKITKIDKNIYNKFNIEILTCLQKNYIKHQNTEEEEDKNNNFKEKNNYDKNIKTIRITNQNEKILLFMPHCDINLYGEILYYIFMYEKLIYQNAHFFIHLENIIFLGNSFDYYKDHIYLYKPLGLPSCILQMLCEYEKHLNIKINQIIVNKLKNHFKEAHFIFYILNYSKEIKFPIFYEFISAFNDLSITLFNKINNKLIFWSNVYKNLID</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPL2</accession>
    <name>A0A1J1GPL2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00394800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527065.1">
        <property type="nucleotide sequence ID" value="XM_028670298.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPL2"/>
    <dbReference type="GeneID" id="39732478"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00394800"/>
    <dbReference type="OrthoDB" id="416344at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42776:SF4">
        <property type="entry name" value="ACYLAMINO-ACID-RELEASING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42776">
        <property type="entry name" value="SERINE PEPTIDASE S9 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="2">
        <location>
            <begin position="637"/>
            <end position="836"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="849" mass="100420" checksum="5F1DFE2A5DB18BCB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPX4</accession>
    <name>A0A1J1GPX4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RTR1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00404600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RPAP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527163.1">
        <property type="nucleotide sequence ID" value="XM_028670407.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPX4"/>
    <dbReference type="GeneID" id="39732576"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00404600"/>
    <dbReference type="OMA" id="YDKNRTY"/>
    <dbReference type="OrthoDB" id="361971at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007308">
        <property type="entry name" value="Rtr1/RPAP2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038534">
        <property type="entry name" value="Rtr1/RPAP2_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04181">
        <property type="entry name" value="RPAP2_Rtr1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51479">
        <property type="entry name" value="ZF_RTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RTR1-type" evidence="3">
        <location>
            <begin position="134"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="741"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="741"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="775"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="828"/>
            <end position="842"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1056" mass="126551" checksum="503E92750216E0EC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPZ2</accession>
    <name>A0A1J1GPZ2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH OST-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00198000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527398.1">
        <property type="nucleotide sequence ID" value="XM_028670669.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPZ2"/>
    <dbReference type="GeneID" id="39730507"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00198000"/>
    <dbReference type="OMA" id="MENEQKH"/>
    <dbReference type="OrthoDB" id="369831at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.610">
        <property type="entry name" value="LOTUS domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041966">
        <property type="entry name" value="LOTUS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025677">
        <property type="entry name" value="OST-HTH-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025605">
        <property type="entry name" value="OST-HTH/LOTUS_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14418">
        <property type="entry name" value="OHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12872">
        <property type="entry name" value="OST-HTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51644">
        <property type="entry name" value="HTH_OST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH OST-type" evidence="1">
        <location>
            <begin position="417"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="690" mass="82419" checksum="AA28906F52898A40" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPZ3</accession>
    <name>A0A1J1GPZ3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00197800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GET4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527396.1">
        <property type="nucleotide sequence ID" value="XM_028670667.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPZ3"/>
    <dbReference type="GeneID" id="39730505"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00197800"/>
    <dbReference type="OMA" id="IFKKCPP"/>
    <dbReference type="OrthoDB" id="10252405at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045048">
        <property type="term" value="P:protein insertion into ER membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007317">
        <property type="entry name" value="GET4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12875">
        <property type="entry name" value="GOLGI TO ER TRAFFIC PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12875:SF0">
        <property type="entry name" value="GOLGI TO ER TRAFFIC PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04190">
        <property type="entry name" value="GET4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="277" mass="33211" checksum="33F747DDB541BD32" modified="2017-02-15" version="1">MEKFKLSKEKLAKEKIENGLHYEAHQLIKSIINRKLQKNQINSCISILFYFSLKFANSKQYVLLCDLMYQCCIILIQKNIKFNLDYANKIIEIFKKCPPKSTEEKYKFMNKSILWSKNEENIYGYLEFHKTIGYSYFEEKQYGLSHNHFIYLDDNEILYKIICLWKKEAYPSESHFFVLRTVLCLLVLNKFNQALNLINMFESNLNRKDVPLPIQLAYLIACSCIYKSLALYEDVKYKYRLILNYDPEFQKYIKVIDTSVFNKRKNDIFSIFQSIFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQE5</accession>
    <name>A0A1J1GQE5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00097200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526088.1">
        <property type="nucleotide sequence ID" value="XM_028672333.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQE5"/>
    <dbReference type="GeneID" id="39729496"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00097200"/>
    <dbReference type="OrthoDB" id="372302at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="747" mass="90582" checksum="D604CA482E1FA3BD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQJ3</accession>
    <name>A0A1J1GQJ3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Bromodomain protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00195700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527377.1">
        <property type="nucleotide sequence ID" value="XM_028670646.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQJ3"/>
    <dbReference type="GeneID" id="39730484"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00195700"/>
    <dbReference type="OMA" id="CYTYNDK"/>
    <dbReference type="OrthoDB" id="422637at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051831">
        <property type="entry name" value="Bromodomain_contain_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22881:SF27">
        <property type="entry name" value="BROMODOMAIN CONTAINING 7_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22881">
        <property type="entry name" value="BROMODOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bromo" evidence="4">
        <location>
            <begin position="37"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="396"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="742" mass="88475" checksum="6195DCAD5FC5663B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQL1</accession>
    <name>A0A1J1GQL1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Lipid/sterol:H+ symporter, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00103600</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the patched family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526152.1">
        <property type="nucleotide sequence ID" value="XM_028673043.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729561"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00103600"/>
    <dbReference type="OMA" id="KPLCAVM"/>
    <dbReference type="OrthoDB" id="6510177at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1640.10">
        <property type="entry name" value="Multidrug efflux transporter AcrB transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051697">
        <property type="entry name" value="Patched_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003392">
        <property type="entry name" value="PTHD_SSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10796">
        <property type="entry name" value="PATCHED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10796:SF92">
        <property type="entry name" value="PATCHED-RELATED, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02460">
        <property type="entry name" value="Patched"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82866">
        <property type="entry name" value="Multidrug efflux transporter AcrB transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="444"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="474"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="509"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="549"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="578"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="930"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1260"/>
            <end position="1282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1288"/>
            <end position="1313"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="9">
        <location>
            <begin position="443"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="713"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="194"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG93330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1319" mass="153621" checksum="2E70870170CB64DD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQS5</accession>
    <name>A0A1J1GQS5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00203800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527457.1">
        <property type="nucleotide sequence ID" value="XM_028670734.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQS5"/>
    <dbReference type="GeneID" id="39730565"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00203800"/>
    <dbReference type="OMA" id="ERNKNLC"/>
    <dbReference type="OrthoDB" id="377126at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="123" mass="14416" checksum="37E8453E75610CC9" modified="2017-02-15" version="1">MKEKNIVSIGLKAQINELEKSINNIATEIDEKTLNNNVKSTYFLKLCEEKKSILIKFLNEEKKKVFDDIENNKSNMLQKISIINEKNEDVKKQSEILMIEKNKNLCFIKNLENKIEKIRGIIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR36</accession>
    <name>A0A1J1GR36_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cochaperone p23, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00212900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the p23/wos2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527547.1">
        <property type="nucleotide sequence ID" value="XM_028670834.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR36"/>
    <dbReference type="GeneID" id="39730656"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00212900"/>
    <dbReference type="OMA" id="WWTKLLR"/>
    <dbReference type="OrthoDB" id="1564555at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051131">
        <property type="term" value="P:chaperone-mediated protein complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06465">
        <property type="entry name" value="p23_hB-ind1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045250">
        <property type="entry name" value="p23-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22932:SF1">
        <property type="entry name" value="CO-CHAPERONE PROTEIN DAF-41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22932">
        <property type="entry name" value="TELOMERASE-BINDING PROTEIN P23 HSP90 CO-CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="3">
        <location>
            <begin position="2"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="168"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="178"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="204"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="247" mass="28576" checksum="8B04AF75AC2BC473" modified="2017-02-15" version="1">MPLYPIVLWAQKKECIYLTIELQEIENVKIDLKEDKLYFFATKDKNEYEFTLNFLKPINVDESKYSTKRNIKFKIIKKEKERWKTINNDGKKHWIKCDWNSWVDTDEENKTTEYDDMAMNSFGGMGGMPDMSQLGNMGGMGDLDFSKLGNMGGDDMANFSGLGGMDQFKNMPNMNNMNDDDSSSYGDDSSEEDDDDEEEDDDIDNKNTEEEKKNECNDSKCNIENENRNDSENKIQDPIVEVQEPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR90</accession>
    <name>A0A1J1GR90_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00243100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527846.1">
        <property type="nucleotide sequence ID" value="XM_028671167.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR90"/>
    <dbReference type="GeneID" id="39730959"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00243100"/>
    <dbReference type="OMA" id="YVHVALM"/>
    <dbReference type="OrthoDB" id="378874at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="604"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="679"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="19"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="80"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="151"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="204"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="215"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="233"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="257"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="271"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="312"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="328"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="349"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="369"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="390"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="413"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="430"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="443"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="462"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="679"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="708"/>
            <end position="754"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="760" mass="87713" checksum="03FA085351CE75AC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRM6</accession>
    <name>A0A1J1GRM6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Palmitoyltransferase</fullName>
            <ecNumber evidence="8">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">DHHC5</name>
        <name evidence="10" type="ORF">PGAL8A_00234500</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527761.1">
        <property type="nucleotide sequence ID" value="XM_028671071.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRM6"/>
    <dbReference type="GeneID" id="39730872"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00234500"/>
    <dbReference type="OMA" id="FWVGFRY"/>
    <dbReference type="OrthoDB" id="9909019at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24161">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24161:SF85">
        <property type="entry name" value="PALMITOYLTRANSFERASE HIP14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="289"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="325"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="489"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="523"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="7">
        <location>
            <begin position="45"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="9">
        <location>
            <begin position="444"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG94947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="649" mass="77930" checksum="3B280F6DD001DA23" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRT3</accession>
    <name>A0A1J1GRT3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00238700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527803.1">
        <property type="nucleotide sequence ID" value="XM_028671119.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730915"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00238700"/>
    <dbReference type="OMA" id="EDCCNNF"/>
    <dbReference type="OrthoDB" id="378389at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="948"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="951"/>
            <end position="970"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1993" mass="236110" checksum="A9DEEFF573560A97" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRU5</accession>
    <name>A0A1J1GRU5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00259400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528002.1">
        <property type="nucleotide sequence ID" value="XM_028671340.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731123"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00259400"/>
    <dbReference type="OrthoDB" id="378516at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051483">
        <property type="entry name" value="MAP7_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15073">
        <property type="entry name" value="MICROTUBULE-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15073:SF1">
        <property type="entry name" value="RETICULOCYTE-BINDING PROTEIN HOMOLOG 2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1459"/>
            <end position="1481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="2912"/>
            <end position="2933"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="838"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1585"/>
            <end position="1606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2123"/>
            <end position="2142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2428"/>
            <end position="2472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2825"/>
            <end position="2850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="841"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="860"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1587"/>
            <end position="1606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2127"/>
            <end position="2138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2428"/>
            <end position="2440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="2455"/>
            <end position="2470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2829"/>
            <end position="2840"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2841"/>
            <end position="2850"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3128" mass="375677" checksum="52E927A06FDDE283" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRU9</accession>
    <name>A0A1J1GRU9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Vacuolar fusion protein MON1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00263900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528046.1">
        <property type="nucleotide sequence ID" value="XM_028671389.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRU9"/>
    <dbReference type="GeneID" id="39731168"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00263900"/>
    <dbReference type="OMA" id="IRKKICC"/>
    <dbReference type="OrthoDB" id="272411at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043972">
        <property type="entry name" value="FUZ/MON1/HPS1_longin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043971">
        <property type="entry name" value="FUZ/MON1/HPS1_longin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004353">
        <property type="entry name" value="Mon1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13027">
        <property type="entry name" value="SAND PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13027:SF7">
        <property type="entry name" value="VACUOLAR FUSION PROTEIN MON1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19036">
        <property type="entry name" value="Fuz_longin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19037">
        <property type="entry name" value="Fuz_longin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01546">
        <property type="entry name" value="YEAST73DUF"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FUZ/MON1/HPS1 first Longin" evidence="2">
        <location>
            <begin position="464"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="domain" description="FUZ/MON1/HPS1 second Longin" evidence="3">
        <location>
            <begin position="589"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="818" mass="96709" checksum="00D3581BB4B048C3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRY3</accession>
    <name>A0A1J1GRY3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Histone H3-like centromeric protein CSE4, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CenH3</name>
        <name evidence="6" type="ORF">PGAL8A_00245900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histone H3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527873.1">
        <property type="nucleotide sequence ID" value="XM_028671196.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRY3"/>
    <dbReference type="GeneID" id="39730987"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00245900"/>
    <dbReference type="OMA" id="EIRAYQS"/>
    <dbReference type="OrthoDB" id="4025405at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22911">
        <property type="entry name" value="HFD_H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000088">
        <property type="entry name" value="Histone H3-like centromeric protein CSE4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000164">
        <property type="entry name" value="Histone_H3/CENP-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45810:SF1">
        <property type="entry name" value="HISTONE H3-LIKE CENTROMERIC PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45810">
        <property type="entry name" value="HISTONE H3.2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00622">
        <property type="entry name" value="HISTONEH3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00428">
        <property type="entry name" value="H3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="5">
        <location>
            <begin position="70"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="164" mass="18946" checksum="E607FE521406004A" modified="2017-02-15" version="1">MVRTKKHVPNHNPVSTFNKEKNINTNKTIPNRLHNQISGKSNNLNNGKLNGLSQNVMNKTRIRRPHRYRPGVLALKEIRAYQASTQLLIPKIPFVRVVKEITRLFELPDEQFRYTPEALLALQTAAEAYLVSLFEDAYLCSLHANRVTLMPKDIHLARRIRGRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRZ2</accession>
    <name>A0A1J1GRZ2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Fam-b protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00004000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528086.1">
        <property type="nucleotide sequence ID" value="XM_028671434.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRZ2"/>
    <dbReference type="GeneID" id="39728562"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00004000"/>
    <dbReference type="OMA" id="HSECENT"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012723830" description="Fam-b protein" evidence="3">
        <location>
            <begin position="20"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="265"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="72"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="410" mass="47878" checksum="FC37666A3B1D2103" modified="2017-02-15" version="1">MIVLSIYTLLLVSFKLINGASYSEDSTKKRSRLLTLPANFFSSPRKKKLFSSYNSSNSESSRPRIKLRERFRSHSECENTSHKDDLNFGESSSNESYLSLSSLEDEFEESQKLGLIPKTKLPTSYDFYLSDELTSNINQNILFQKPYQCNLNNDNSEEDEKNKTSSNKIFSLNRGMFNLQTKKDNTDKVKSLDKNESKKNYFARPLSFIRRRKSNSNFRIRDTSHLQSNNDCKKDYKNYAVRGIFTWANKDVDMLRTRPHRTCSLSSHVERNLNLKEENEELIELYASCINELNKLKNEDNLESRINEDNCFFEVPENKDVERKKFMKSKSEELKKMSSIFRMYEIKKKESKKNILTRSSSLRGHDKGIFDDNINISLTFKKKLKENKEENTSGDNVSEHSCCIESIDNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS17</accession>
    <name>A0A1J1GS17_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SNARE protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00250000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527913.1">
        <property type="nucleotide sequence ID" value="XM_028671241.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS17"/>
    <dbReference type="GeneID" id="39731028"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00250000"/>
    <dbReference type="OMA" id="SFANFYQ"/>
    <dbReference type="OrthoDB" id="374178at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.50">
        <property type="entry name" value="Longin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="187" mass="22112" checksum="57BFF33BEBE1D8A7" modified="2017-02-15" version="1">MEDFKIIYASIIKFKDKIPIFTYYTNIESELRVELVRSLNLFSQSSSIGAFPDSLPFEHGIIYSLYNKNLTLIYIIITKKGEMTDKHAFSFLEECMNKLENNIDYKNLHRLPKNYYSRSFANFYQNLIKKYNAEYLNNYERFDKKIVRILSTIHKGIESSLKNKNNLSKLERRLSSLAINAKIVCFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS69</accession>
    <name>A0A1J1GS69_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00004100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528087.1">
        <property type="nucleotide sequence ID" value="XM_028671435.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS69"/>
    <dbReference type="GeneID" id="39728563"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00004100"/>
    <dbReference type="OMA" id="NYMAASH"/>
    <dbReference type="OrthoDB" id="372195at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="415"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="609"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="660"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1203"/>
            <end position="1225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1246" mass="154450" checksum="1BC7F02C682E8B2B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSD5</accession>
    <name>A0A1J1GSD5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Hexose transporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">HT</name>
        <name evidence="18" type="ORF">PGAL8A_00019600</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Sodium-independent facilitative hexose transporter. Can transport D-glucose and D-fructose. Can transport D-mannose, D-galactose, D-xylose and D-glucosamine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>D-fructose(out) = D-fructose(in)</text>
            <dbReference type="Rhea" id="RHEA:60372"/>
            <dbReference type="ChEBI" id="CHEBI:37721"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:60373"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>D-galactose(in) = D-galactose(out)</text>
            <dbReference type="Rhea" id="RHEA:34915"/>
            <dbReference type="ChEBI" id="CHEBI:4139"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="7">
            <dbReference type="Rhea" id="RHEA:34917"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>D-glucosamine(out) = D-glucosamine(in)</text>
            <dbReference type="Rhea" id="RHEA:78423"/>
            <dbReference type="ChEBI" id="CHEBI:58723"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:78424"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>D-glucose(out) = D-glucose(in)</text>
            <dbReference type="Rhea" id="RHEA:60376"/>
            <dbReference type="ChEBI" id="CHEBI:4167"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:60377"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-mannose(out) = D-mannose(in)</text>
            <dbReference type="Rhea" id="RHEA:78391"/>
            <dbReference type="ChEBI" id="CHEBI:4208"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:78392"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-xylose(out) = D-xylose(in)</text>
            <dbReference type="Rhea" id="RHEA:78427"/>
            <dbReference type="ChEBI" id="CHEBI:53455"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:78428"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528238.1">
        <property type="nucleotide sequence ID" value="XM_028671602.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSD5"/>
    <dbReference type="GeneID" id="39728718"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00019600"/>
    <dbReference type="OMA" id="WAITASF"/>
    <dbReference type="OrthoDB" id="6612291at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015149">
        <property type="term" value="F:hexose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17315">
        <property type="entry name" value="MFS_GLUT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045263">
        <property type="entry name" value="GLUT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503:SF8">
        <property type="entry name" value="FACILITATED GLUCOSE TRANSPORTER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23503">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 15" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="202"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="327"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="357"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="388"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="425"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="454"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="17">
        <location>
            <begin position="28"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00044656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00045752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="CRG95427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="502" mass="56410" checksum="F1D5C8E26C3A3AE6" modified="2017-02-15" version="1">MKTDQDNTMESSIVKEKKDKFFNTSFKYVLSACIASFIFGYQVSVLNTIKNFIVVEFEWCKGADRLNCDTNTIQSSFLLASVFIGAVIGSGFSGYLVQFGRRFSLLVIYNFFVIVSILTSITHHFHTILFARLLSGFGVGLITVSVPMYISEMTHKDKKGAYGVLHQLFITFGIFIAVLLGLALGSGPNAKSKDPLSDFEKIWWRLMFLFPSFMSLFGIFLLVVFFKEETPYYLFEHGKVEESKKILKKIYGTEDVDEPLKAIQDAIEQNEAAKRNSLSLLAALKIPSYRYVILLGCILSGFQQLTGINVLVANSNELYKEFLNDNLITILSVIMTAVNFLMTFPAIYIVEKLGRKTLLLWGCVGVIIAYLPTAIANEIDKNAKFVKVLSIVATFIMIISFAVSYGPVLWIYLHEMFPSEIKDSAASLASLINWLCAIIVVFPSDVIIKKSPSVLFIIFAIMSIISFLFILFFVKETKGNEIGTSPYISMEERQKYMVKAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSH0</accession>
    <name>A0A1J1GSH0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fam-h protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00267100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000036">
        <property type="protein sequence ID" value="CRG95468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528278.1">
        <property type="nucleotide sequence ID" value="XM_028671647.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSH0"/>
    <dbReference type="GeneID" id="39731200"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00267100"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="187" mass="22239" checksum="355B066C2C65739C" modified="2017-02-15" version="1">MNSLFFLIKYLMFAFLILILQYSNNISFESWNIKKISEGTFRLKAKRTLSENIFKKSKSESTENLLDALEKEEIYEKQDEMEKNLIKSNAPKSIFHSFIIPKPSETIVELLNEHNVNKQEVTKYINKSIGSFFFSLISLSLPLYLVYLSHMEYFYNWKEHSEMYRLLMSYCILMISCFICLLYHKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT35</accession>
    <name>A0A1J1GT35_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ATP-dependent protease, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00286500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase S16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528476.1">
        <property type="nucleotide sequence ID" value="XM_028671867.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT35"/>
    <dbReference type="GeneID" id="39731398"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00286500"/>
    <dbReference type="OMA" id="WLTNIPW"/>
    <dbReference type="OrthoDB" id="2411602at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054594">
        <property type="entry name" value="Lon_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008269">
        <property type="entry name" value="Lon_proteolytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10046">
        <property type="entry name" value="ATP DEPENDENT LON PROTEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05362">
        <property type="entry name" value="Lon_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22667">
        <property type="entry name" value="Lon_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00830">
        <property type="entry name" value="ENDOLAPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
        <property type="entry name" value="LON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51787">
        <property type="entry name" value="LON_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51786">
        <property type="entry name" value="LON_PROTEOLYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 6 9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Lon N-terminal" evidence="8">
        <location>
            <begin position="38"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="Lon proteolytic" evidence="7">
        <location>
            <begin position="909"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="993"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="1036"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG95668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1093" mass="129516" checksum="239EBD6BE4771E4A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT40</accession>
    <name>A0A1J1GT40_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">H/ACA ribonucleoprotein complex subunit 4, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00289100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pseudouridine synthase TruB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528502.1">
        <property type="nucleotide sequence ID" value="XM_028671895.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT40"/>
    <dbReference type="GeneID" id="39731424"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00289100"/>
    <dbReference type="OMA" id="GPFKEDE"/>
    <dbReference type="OrthoDB" id="10250002at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031429">
        <property type="term" value="C:box H/ACA snoRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000495">
        <property type="term" value="P:box H/ACA sno(s)RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990481">
        <property type="term" value="P:mRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031118">
        <property type="term" value="P:rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031120">
        <property type="term" value="P:snRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02572">
        <property type="entry name" value="PseudoU_synth_hDyskerin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21148">
        <property type="entry name" value="PUA_Cbf5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2350.10:FF:000001">
        <property type="entry name" value="H/ACA ribonucleoprotein complex subunit CBF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="entry name" value="PUA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012960">
        <property type="entry name" value="Dyskerin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004802">
        <property type="entry name" value="tRNA_PsdUridine_synth_B_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032819">
        <property type="entry name" value="TruB_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00425">
        <property type="entry name" value="CBF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003280">
        <property type="entry name" value="PRK04270.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23127">
        <property type="entry name" value="CENTROMERE/MICROTUBULE BINDING PROTEIN CBF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23127:SF0">
        <property type="entry name" value="H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT DKC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08068">
        <property type="entry name" value="DKCLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01472">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16198">
        <property type="entry name" value="TruB_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01136">
        <property type="entry name" value="DKCLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50890">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <feature type="domain" description="Dyskerin-like" evidence="5">
        <location>
            <begin position="20"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="PUA" evidence="4">
        <location>
            <begin position="269"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="396"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="397"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="422"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="441"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="474" mass="53957" checksum="D914781E03C72270" modified="2017-02-15" version="1">MEEIKADYKIEPERKEAVIDTSNWPLLLKNYDKLNIRTSHFTPLPMGNSPYSRSLEEYLKYGIINLDKPSNPSSHEVVSWIRKILRCEKTGHSGTLDPKVTGVLLVCLNRATRLVKSQQESGKEYVCVCKFHSKPKSIEDVKLVLNNFQGAIFQRPPLICAVKRQLRVRTIYETKLLDYDDINNLCVFWVKCQAGTYIRTLCEHVGLLLGVGAHMQELRRVKSGNMTEYDNMCTLHDILDAQYIYDTTGDETYLRKIIAPLEKLLVNFPRIVIKDSAVNAICYGAKLTIPGVLRFDSNIDINSEIVLMTTKGEAVALAIAQMTSTVIATVDHGIVALTKRVIMDRDTYDVKWGFGNRSMEKKKLILAGLLDKYGKPNEKTPLSWIKSEGYAPKLIGDTSNYTLNTENNNISEEKRNNENTENDPNNQRNRSNHNSSLNNNDEQKITELLESNKPKNNDTEQPDSSVLKKKRRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT91</accession>
    <name>A0A1J1GT91_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NTF2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00295500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528558.1">
        <property type="nucleotide sequence ID" value="XM_028671957.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT91"/>
    <dbReference type="GeneID" id="39731488"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00295500"/>
    <dbReference type="OMA" id="YYYVLHT"/>
    <dbReference type="OrthoDB" id="378854at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018222">
        <property type="entry name" value="Nuclear_transport_factor_2_euk"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50177">
        <property type="entry name" value="NTF2_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NTF2" evidence="2">
        <location>
            <begin position="365"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="645"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="840"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="966"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="105"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="217"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="302"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="645"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="663"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="753"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="783"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="840"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="981"/>
            <end position="995"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1158" mass="137191" checksum="CA07E438ED5C7823" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTE4</accession>
    <name>A0A1J1GTE4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Abscisic acid G-protein coupled receptor-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00292300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528527.1">
        <property type="nucleotide sequence ID" value="XM_028671923.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTE4"/>
    <dbReference type="GeneID" id="39731456"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00292300"/>
    <dbReference type="OMA" id="HIVHINI"/>
    <dbReference type="OrthoDB" id="264392at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025969">
        <property type="entry name" value="ABA_GPCR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022535">
        <property type="entry name" value="Golgi_pH-regulator_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015672">
        <property type="entry name" value="GPHR/GTG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15948">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR 89-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15948:SF0">
        <property type="entry name" value="GOLGI PH REGULATOR A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12430">
        <property type="entry name" value="ABA_GPCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12537">
        <property type="entry name" value="GPHR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="72"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="713"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="792"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="830"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="880"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="domain" description="Golgi pH regulator conserved" evidence="7">
        <location>
            <begin position="241"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="Abscisic acid G-protein coupled receptor-like" evidence="6">
        <location>
            <begin position="710"/>
            <end position="902"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="911" mass="109428" checksum="09154C228A8D830D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTK4</accession>
    <name>A0A1J1GTK4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquinol-cytochrome c chaperone domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00307400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528670.1">
        <property type="nucleotide sequence ID" value="XM_028672081.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTK4"/>
    <dbReference type="GeneID" id="39731607"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00307400"/>
    <dbReference type="OrthoDB" id="369458at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021150">
        <property type="entry name" value="Ubiq_cyt_c_chap"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03981">
        <property type="entry name" value="Ubiq_cyt_C_chap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquinol-cytochrome c chaperone" evidence="1">
        <location>
            <begin position="174"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="307" mass="37472" checksum="BE44E500968DA24F" modified="2017-02-15" version="1">MNKCFVSIYKFRYHHYVKRFKCSINNAINDKKLKWRTTEESYCEYLLSPEEEKELRKNHLNIISNNNINIDDNIIYESIKDCEKDNISAYYFNLNSNLNNLKNSSSIISYYFKPLSNIIKKFKEIPVINYLYKNIFFKYRVNIHIFISPIYERINNEKLFLKFNLNKNDVREIMYFLCIHVWIYCVKLNMINDNHLKVLLFEKVWDYYRALIMKYKISEFSFNTYLINMQEYSLGFCVGLDECISKKLYAGQIYHLLFNHIYRENKNFKNSKELTNLTIYCIRMYRFICLLPKENFLQAKFTWPDVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTM6</accession>
    <name>A0A1J1GTM6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00284600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528457.1">
        <property type="nucleotide sequence ID" value="XM_028671845.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTM6"/>
    <dbReference type="GeneID" id="39731379"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00284600"/>
    <dbReference type="OMA" id="YAYEHQL"/>
    <dbReference type="OrthoDB" id="386175at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="306"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="418" mass="49433" checksum="3CD478D42D7F62FD" modified="2017-02-15" version="1">MVTKSEKRKKTKIKAYDIDESKKIFLYAYEHQLKNEKIDWKKAEEMKITKHSGGSMRNHYLNSIKNEISLYLEMYPEEAAKIFNKVKRLKREEKKKKIFDFQNNLVKQRSNISLNRLTKCKSSNFNKHNSLNISNMFSMKNRNTDTKYKSFHNKNDNNEKIKKKNLNNNNKINELNLNRNLSKKSKLKRVRIVNKDIVTKNKKINKKKNNKSSKSIIIKSALERSNKIVNNSLNKENNDKMNKNVNEKTFKKNTEKTKEKNAKIYENYEKKLNEKNSKTTNEDFIENKKNRKFIKDENEIQIKLEKIDSNEKINKELNELKMLNKNLIERNQNISKGDNNSDKLNLESKLTKKSNEKKISLQNKIINKNSTLNDNINELNDLNNSIESPESNISNNNGENKKNTITSILGYIYKKIFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTP1</accession>
    <name>A0A1J1GTP1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Ribonucleoside-diphosphate reductase</fullName>
            <ecNumber evidence="3 12">1.17.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PGAL8A_00308800</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 12">Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 12">
            <text>a 2'-deoxyribonucleoside 5'-diphosphate + [thioredoxin]-disulfide + H2O = a ribonucleoside 5'-diphosphate + [thioredoxin]-dithiol</text>
            <dbReference type="Rhea" id="RHEA:23252"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="EC" id="1.17.4.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Heterodimer of a large and a small subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 12">Belongs to the ribonucleoside diphosphate reductase large chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="3 12"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528684.1">
        <property type="nucleotide sequence ID" value="XM_028672097.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTP1"/>
    <dbReference type="GeneID" id="39731621"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00308800"/>
    <dbReference type="OMA" id="TLFMTDK"/>
    <dbReference type="OrthoDB" id="3000483at2759"/>
    <dbReference type="UniPathway" id="UPA00326"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005971">
        <property type="term" value="C:ribonucleoside-diphosphate reductase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009263">
        <property type="term" value="P:deoxyribonucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01679">
        <property type="entry name" value="RNR_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.70.20:FF:000010">
        <property type="entry name" value="Ribonucleoside-diphosphate reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.70.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005144">
        <property type="entry name" value="ATP-cone_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013346">
        <property type="entry name" value="NrdE_NrdA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000788">
        <property type="entry name" value="RNR_lg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013509">
        <property type="entry name" value="RNR_lsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008926">
        <property type="entry name" value="RNR_R1-su_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039718">
        <property type="entry name" value="Rrm1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02506">
        <property type="entry name" value="NrdE_NrdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11573">
        <property type="entry name" value="RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11573:SF6">
        <property type="entry name" value="RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03477">
        <property type="entry name" value="ATP-cone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02867">
        <property type="entry name" value="Ribonuc_red_lgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00317">
        <property type="entry name" value="Ribonuc_red_lgN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01183">
        <property type="entry name" value="RIBORDTASEM1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51998">
        <property type="entry name" value="PFL-like glycyl radical enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48168">
        <property type="entry name" value="R1 subunit of ribonucleotide reductase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51161">
        <property type="entry name" value="ATP_CONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00089">
        <property type="entry name" value="RIBORED_LARGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 12" id="KW-0215">Deoxyribonucleotide synthesis</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-cone" evidence="13">
        <location>
            <begin position="42"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG95876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="847" mass="97103" checksum="C1A41D7283EBFC4B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTS7</accession>
    <name>A0A1J1GTS7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00306700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528663.1">
        <property type="nucleotide sequence ID" value="XM_028672073.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTS7"/>
    <dbReference type="GeneID" id="39731600"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00306700"/>
    <dbReference type="OMA" id="MKPKMWI"/>
    <dbReference type="OrthoDB" id="372577at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="347" mass="40999" checksum="E1DB97C3AEEE4DCA" modified="2017-02-15" version="1">MGNIASEQKKKPMTLQDLTTKIGEYRTINEGDPEMVEDPEFPQEMMLEALNKNNTIEGNSIQGTYVYYPNKRKPKMWIGNYKILNPEDILCKNVAEKIGMTEIEWKNYIKRKSTFQEEPKKNENFPHFNYPSSEQSRALKEIMKNSNIDYSYDKNEFLEHYNDKGYIIDSPHFNNNHELKNDYDYDQYPNNIEVIKNDYSLDENIYCDKKSTKDKKIFEDSYINKLNDEITKIREEQERMINEECKDIYAYSKSNTDHIIIPQKKRSFLIEENDTIAYDNKNIIEKLMNEKKNKVNSQFCALKQKNKKDGYKNLSSMSTKGSLGLDNSNINENISNKNVYLNRTLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTY3</accession>
    <name>A0A1J1GTY3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ubiquitin fusion degradation protein UFD1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">UFD1</name>
        <name evidence="7" type="ORF">PGAL8A_00289600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UFD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528507.1">
        <property type="nucleotide sequence ID" value="XM_028671901.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTY3"/>
    <dbReference type="GeneID" id="39731429"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00289600"/>
    <dbReference type="OMA" id="WMMQQLC"/>
    <dbReference type="OrthoDB" id="422728at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034098">
        <property type="term" value="C:VCP-NPL4-UFD1 AAA ATPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.50">
        <property type="entry name" value="Ubiquitin fusion degradation protein UFD1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029067">
        <property type="entry name" value="CDC48_domain_2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004854">
        <property type="entry name" value="Ufd1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042299">
        <property type="entry name" value="Ufd1-like_Nn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055417">
        <property type="entry name" value="UFD1_N1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055418">
        <property type="entry name" value="UFD1_N2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12555">
        <property type="entry name" value="UBIQUITIN FUSION DEGRADATON PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12555:SF13">
        <property type="entry name" value="UBIQUITIN RECOGNITION FACTOR IN ER-ASSOCIATED DEGRADATION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03152">
        <property type="entry name" value="UFD1_N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24842">
        <property type="entry name" value="UFD1_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54585">
        <property type="entry name" value="Cdc48 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin fusion degradation protein UFD1 N-terminal subdomain 1" evidence="5">
        <location>
            <begin position="22"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin fusion degradation protein UFD1 N-terminal subdomain 2" evidence="6">
        <location>
            <begin position="118"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF24842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="281" mass="32284" checksum="160AEEE8BACDE85D" modified="2017-02-15" version="1">MWSFTNFNNIWGRDFLNISDPFTEEYTCYPVSFIGKDDMENGNKIILPQTALNALARRHISWPMLFEVSNPITEKKTHSGVLEFISDEGTCHMPYWMMQQLQLKEGDIVRVKSVSLPKGTFVKLKPCSKDFMELSNHRAVLETALRNYATLTVGDNIVIHYLGKTYEIKIVDLKPAFACTIIETDVEVEFQEPLDYNENIQSVEETLPNEESKFKGKGQRTDGKACKNIKKENSKPKIIENKEPWKDKLVGGVRTKCIEYDELLKKGHIPGIVGKFKERKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU75</accession>
    <name>A0A1J1GU75_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00324700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000052">
        <property type="protein sequence ID" value="CRG96034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528842.1">
        <property type="nucleotide sequence ID" value="XM_028672273.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731780"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00324700"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="668"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="290"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="384"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="468"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1125"/>
            <end position="1176"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1216"/>
            <end position="1257"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1432"/>
            <end position="1459"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1510"/>
            <end position="1541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="393"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="411"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="469"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="489"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="526"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1601" mass="188877" checksum="FCEE8E511AE28830" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU80</accession>
    <name>A0A1J1GU80_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00330200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528894.1">
        <property type="nucleotide sequence ID" value="XM_028672331.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU80"/>
    <dbReference type="GeneID" id="39731832"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00330200"/>
    <dbReference type="OMA" id="YPKENIR"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="158" mass="17691" checksum="5E3FBD82B36E9066" modified="2017-02-15" version="1">MEGNKYPKENIRLVLEDDKAISGNTSDPFFITNLSPFPSSSTAEMQQSDSGVIPIYQTSNLTAEENPLLMNALAILVLLLNMFTIKYKRKVINRTPFKTIGDLKVEIVEDIQTLSLTPKENPLESDPQSTENEDGEGDNFFQESDDNYSETGDMSVME</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU97</accession>
    <name>A0A1J1GU97_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00228300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527701.1">
        <property type="nucleotide sequence ID" value="XM_028671005.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU97"/>
    <dbReference type="GeneID" id="39730810"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00228300"/>
    <dbReference type="OrthoDB" id="342064at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="1">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="235" mass="28499" checksum="DCB5E7EC316491E2" modified="2017-02-15" version="1" fragment="single">LGEYSNLNNELEKNNITDDNSRNICDDINNIHNENCKEKKSDNNKLQNMKKIYNNELISDYQLKWLINFDEEINDALKADYNKNIDIEKTKEFFNILKKNYILKTNNNENEIRCAKCKKLFHNIKDVPNHIFTKHNQIKMKLITETEVEIMKKNFFEAPHSFHFFYMMEKKYNSYSRNYLSKNFYKRNKNYKNENFHLIPKNAKNDYKDVDEPNLPVFENLKNDIKKKNDFYDDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUC1</accession>
    <name>A0A1J1GUC1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00230800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527725.1">
        <property type="nucleotide sequence ID" value="XM_028671031.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUC1"/>
    <dbReference type="GeneID" id="39730835"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00230800"/>
    <dbReference type="OMA" id="ICISSYK"/>
    <dbReference type="OrthoDB" id="391503at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013584">
        <property type="entry name" value="RAP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08373">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00952">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51286">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RAP" evidence="1">
        <location>
            <begin position="443"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="508" mass="61815" checksum="22D1F274E6472C0A" modified="2017-02-15" version="1">MMIILFRNILRRSFSSLKNELQKFETLSKNFVNSIEKYKQEKDISITSYVNYKKEIKECIGFLFNNNLDSLEEKDFKTIFTYSILLSRRVLIHKDLTKNVLLRYITIKKENKEKCIDDNQRYTQKDEIKELLLMLKFLFYLNIDFDKVIYNYLYSELNNEIEFYTLEELVETIKIISSFKNKKWVNYKVFSRCINEVIKRNQEEKNDIYKFLITIIKSCSRLNYEIYDIQDLLESFRQNYDKNIKGNMHILIKVLYNLFLCNYHNYKNTNQLINILKEEIMQVKKEEDYPLYNKYLYNSNVILDNNLDFNTGISKNEFDVNICNDNINNIHEMYFKTKERSKDILSNSAITSINLYRLKFIDLVIRSDNYLYNCFYSPNSHFFDFIKQLNLESKNTKETIFSKQVKFFIRENGFRIEYKYVNIYPIVFLSDFKNTYVEFVHNICINKKMKDSPNIFHKNYLNYKIKHLKFLGWDAITLYEYEWKKLRSYNEKFEYIKKAFKSIKSSSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUE8</accession>
    <name>A0A1J1GUE8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00307900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528675.1">
        <property type="nucleotide sequence ID" value="XM_028672086.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUE8"/>
    <dbReference type="GeneID" id="39731612"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00307900"/>
    <dbReference type="OrthoDB" id="370027at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1053" mass="127557" checksum="130974D0F31D0635" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUG1</accession>
    <name>A0A1J1GUG1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptidyl-prolyl cis-trans isomerase, putative</fullName>
            <ecNumber evidence="6">5.2.1.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00338700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528974.1">
        <property type="nucleotide sequence ID" value="XM_028672419.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUG1"/>
    <dbReference type="GeneID" id="39731917"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00338700"/>
    <dbReference type="OMA" id="YYECISE"/>
    <dbReference type="OrthoDB" id="2423701at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039663">
        <property type="entry name" value="AIP/AIPL1/TTC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11242">
        <property type="entry name" value="ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11242:SF0">
        <property type="entry name" value="TPR_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="346"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="370"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="189"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="395" mass="47347" checksum="70E6DD34E07BD608" modified="2017-02-15" version="1">MTIKTSEDVYKFVKDCIKIKEEVENAKIVKKKEKNRNESKNNLSKYNFDYSKFESCIKEIEEEEEEKKKIEKNKHHFINDRNPCTHDHSKERQLYEKDSKEKIKASNAFNEEGKKAFYEKNFKLACVYFRKGLIQLDYSFPDLEQEKCEQKKLEINLHLNMALTKFHMSKYYECISECSTVLNFDQNNIKAYYRKGQAYMKLDLYNEAKQEFLKVLEIDPSNNNAKRSLLDLKEKILIYNKKNKLVCSKFFSFNENKTKNEKKKANIQSNLNESNYENVNEKINNKNLLTDKDNIKEMDKNNNFDKNLINKIKDKKSYLCKVKKYIFMINSTSCFKNYYEFLMNNVLLCIFICFSIFSLIFTFVFTSYKNFLTCISFFPILSFIGFFFIYVLKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUM1</accession>
    <name>A0A1J1GUM1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00321400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000048">
        <property type="protein sequence ID" value="CRG96001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528809.1">
        <property type="nucleotide sequence ID" value="XM_028672237.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731747"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00321400"/>
    <dbReference type="OMA" id="QHRINAG"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="711"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="405"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="477"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="521"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="888"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1198"/>
            <end position="1229"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1501"/>
            <end position="1535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="405"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="430"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="477"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="489"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="521"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1676" mass="197519" checksum="A20B5384B809F64F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUW8</accession>
    <name>A0A1J1GUW8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Dynein heavy chain, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PGAL8A_00349500</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynein heavy chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529082.1">
        <property type="nucleotide sequence ID" value="XM_028672540.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732025"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00349500"/>
    <dbReference type="OMA" id="WAYLVND"/>
    <dbReference type="OrthoDB" id="424310at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097729">
        <property type="term" value="C:9+2 motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008569">
        <property type="term" value="F:minus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060294">
        <property type="term" value="P:cilium movement involved in cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000738">
        <property type="entry name" value="Dynein heavy chain axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.20:FF:000012">
        <property type="entry name" value="Dynein heavy chain, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001275">
        <property type="entry name" value="Dynein heavy chain, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.710:FF:000007">
        <property type="entry name" value="Putative dynein heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.100">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.180.20">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.720">
        <property type="entry name" value="Region D6 of dynein motor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035699">
        <property type="entry name" value="AAA_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041658">
        <property type="entry name" value="AAA_lid_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042219">
        <property type="entry name" value="AAA_lid_11_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011704">
        <property type="entry name" value="ATPase_dyneun-rel_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041589">
        <property type="entry name" value="DNAH3_AAA_lid_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042222">
        <property type="entry name" value="Dynein_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043157">
        <property type="entry name" value="Dynein_AAA1S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041466">
        <property type="entry name" value="Dynein_AAA5_ext"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041228">
        <property type="entry name" value="Dynein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043160">
        <property type="entry name" value="Dynein_C_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024743">
        <property type="entry name" value="Dynein_HC_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024317">
        <property type="entry name" value="Dynein_heavy_chain_D4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004273">
        <property type="entry name" value="Dynein_heavy_D6_P-loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013602">
        <property type="entry name" value="Dynein_heavy_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042228">
        <property type="entry name" value="Dynein_linker_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10676">
        <property type="entry name" value="DYNEIN HEAVY CHAIN FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10676:SF392">
        <property type="entry name" value="DYNEIN HEAVY CHAIN-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07728">
        <property type="entry name" value="AAA_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12774">
        <property type="entry name" value="AAA_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12775">
        <property type="entry name" value="AAA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12780">
        <property type="entry name" value="AAA_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17857">
        <property type="entry name" value="AAA_lid_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18198">
        <property type="entry name" value="AAA_lid_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08393">
        <property type="entry name" value="DHC_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17852">
        <property type="entry name" value="Dynein_AAA_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18199">
        <property type="entry name" value="Dynein_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03028">
        <property type="entry name" value="Dynein_heavy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12777">
        <property type="entry name" value="MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-0243">Dynein</keyword>
    <keyword evidence="3" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="11" id="KW-0505">Motor protein</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="15">
        <location>
            <begin position="1835"/>
            <end position="1973"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="15">
        <location>
            <begin position="2191"/>
            <end position="2326"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="15">
        <location>
            <begin position="2513"/>
            <end position="2658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="668"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1741"/>
            <end position="1770"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="2117"/>
            <end position="2142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="4055"/>
            <end position="4166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="4828"/>
            <end position="4852"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="1117"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="3443"/>
            <end position="3484"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="4201"/>
            <end position="4256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="677"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="691"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="4070"/>
            <end position="4081"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="4082"/>
            <end position="4096"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="4097"/>
            <end position="4128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="4135"/>
            <end position="4166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="CRG96277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="5144" mass="605258" checksum="B776341FD5DD902E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV27</accession>
    <name>A0A1J1GV27_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Actin-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00330900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528899.1">
        <property type="nucleotide sequence ID" value="XM_028672337.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV27"/>
    <dbReference type="GeneID" id="39731839"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00330900"/>
    <dbReference type="OMA" id="MFHNFVG"/>
    <dbReference type="OrthoDB" id="5132116at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="490" mass="56575" checksum="CD89AEA0D0624A4D" modified="2017-02-15" version="1">MFQNIQTIILDINDGEMRAGYSGECSPRYNSNLILGLPLGHNATLKHTIFPLLPEIKRDNVELLYGMKYIYNDNNNSKYDINYEVMEKLFEDISGSKALDDNFQDHPILLTEPNKTDSKYREKFTELMFESYNVFQLFLSRRSVLSCYGCARTSGLVLNVEKNCTNLCGIQEGYIFQKHIEEVPIGGDLIDRIYLSYLENIKKIKIYPYFSIDKNQNSEKRNNEVKILKCPLVTKSYYLWGSLYVVNQLKEDLINDRQNTCDKNKNSSNTNETNNYKLPDGNIIDECTVNSLNLIIPYVFFRKKYNQNNISKISGITSLNNIDLNLFYDSLKNLKLPILYTYNYKINSSNSVIEKILENPADKNSNICHSDQIDNYFEIFDGLQNFVKKGILSFISSNINLDEVLNFLIVTGESTMFNNFIGILKSYLPFIDTIKEKNTKIIYSKGTDRKYNCFIGASILSSLGSFSQFCMTKNEYEEYGVKNIVDKKCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV51</accession>
    <name>A0A1J1GV51_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RuvB-like helicase</fullName>
            <ecNumber evidence="8">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00333300</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the RuvB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528923.1">
        <property type="nucleotide sequence ID" value="XM_028672363.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV51"/>
    <dbReference type="GeneID" id="39731863"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00333300"/>
    <dbReference type="OMA" id="AMGICGQ"/>
    <dbReference type="OrthoDB" id="10060499at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.360:FF:000001">
        <property type="entry name" value="RuvB-like helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.360">
        <property type="entry name" value="RuvB-like helicase, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027238">
        <property type="entry name" value="RuvB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041048">
        <property type="entry name" value="RuvB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042487">
        <property type="entry name" value="RuvBL1/2_DNA/RNA_bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010339">
        <property type="entry name" value="TIP49_P-loop"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11093">
        <property type="entry name" value="RUVB-RELATED REPTIN AND PONTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06068">
        <property type="entry name" value="TIP49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17856">
        <property type="entry name" value="TIP49_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="9">
        <location>
            <begin position="81"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG96118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="475" mass="53359" checksum="0F1A00B276866392" modified="2017-02-15" version="1">MQINLANINSTGETKKERVNIHSHIKGLGVNTNIYMHENEVNLSDEKYSMFFDNTCGLVGQYKAREASLFLVDLIKKKKLAGKCILLAGPSGSGKSALAIGISREINKKMPFVFLSGSEVYSNEIKKTEVILEAFRKSIHIKIKEEKLVYEGEVVDMVVEENECLYSLNKAKQINAIIITLKAVKGSKTLRLAPKIHEQIVREKIKIGDVIYIETNTGHVKRLGRCNAYSKEFDIEFDEYVSLPKGEVHKKKEVVQQISLHDIDLANANPTVGEDLASVLNSYLRPKKTEITEKLRVEINKTVNKFLEMGLAEIIPGVLYIDEAHMLDIECFSYLNRAIESPLAPIVIMATNRGICTVKGTDNIEPHGIPVDLLDRLIIIKTFPYTLKEIVQILALRAHTEKINISEEGMNYLAKIGIQSSLRFAMLLLEPSRILASLEGKSIIDIKHIEQADELFMDAKTSAHRVAEQSNKFVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV88</accession>
    <name>A0A1J1GV88_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00369000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529270.1">
        <property type="nucleotide sequence ID" value="XM_028672748.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV88"/>
    <dbReference type="GeneID" id="39732220"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00369000"/>
    <dbReference type="OMA" id="DFVFSYP"/>
    <dbReference type="OrthoDB" id="371956at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="296" mass="35668" checksum="DF59C9E874711B18" modified="2017-02-15" version="1">MGEYIRKIPFFNDYEKKKDLLKFPHLKESDNDGKKNLNNNINQDVYYIKKRENMKDILTYLPNLNNRTQRDIFNERKNKLKEDISESYYSYEEKFPFLINTCVKKIEETRNMGDVLNNKYEPDETRKTRIYEGIKTKTMLLEARKKLYMDELKSINREAKNYMYNIIKKNNKNNMDIIKDKNKILTLKNYGLGLAPSNFVFSYPHIQAKGRGGFATDIMKSIILKNKNEKINKKINVNDINDLYKDKNNKEREEKVFLMINRFKYINYTRKSYSVDNYLKEKPHIILRYKGFQRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV96</accession>
    <name>A0A1J1GV96_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00369800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529278.1">
        <property type="nucleotide sequence ID" value="XM_028672758.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732228"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00369800"/>
    <dbReference type="OMA" id="IFLHYYF"/>
    <dbReference type="OrthoDB" id="340611at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="468"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="498"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="523"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1102"/>
            <end position="1125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1131"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1217"/>
            <end position="1237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1269"/>
            <end position="1300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1332"/>
            <end position="1356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1269"/>
            <end position="1285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1291"/>
            <end position="1300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1338"/>
            <end position="1350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1445" mass="171948" checksum="86E61C8E800078C2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVH7</accession>
    <name>A0A1J1GVH7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Alternative splicing factor ASF-1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ASF1</name>
        <name evidence="8" type="ORF">PGAL8A_00346400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529051.1">
        <property type="nucleotide sequence ID" value="XM_028672505.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVH7"/>
    <dbReference type="GeneID" id="39731994"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00346400"/>
    <dbReference type="OMA" id="TIAEYDC"/>
    <dbReference type="OrthoDB" id="1099063at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003:SF62">
        <property type="entry name" value="SERINE_ARGININE (SR)-TYPE SHUTTLING MRNA BINDING PROTEIN NPL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="8"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="99"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="257" mass="29960" checksum="2FD85715D20BC616" modified="2017-02-15" version="1">MKKVSNGSRLYVGNIPGSATKQEIIKIFEEHGKISDIDIKYNRNSNGTNYAFIEYENPKSAEKTILKRNGKKFKGYMLKVEYSIEKKNKDVNDFNRSQYRVVVKNLPKVLKWKSIKEFLSKAGKLIYTHAENGITIAEYEDKESMLKAVNTLDRIIYNNKRKMYVRVLKDIPYDESDMDDNLDYNVFSSFNKNDNLNKKFNFFSSNTSAKVSNYSDMVNDNSNNNSNNNNLTIKKNKQNIGYNTNKNIKYESFKEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVM5</accession>
    <name>A0A1J1GVM5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GINS subunit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00246600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GINS2/PSF2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527880.1">
        <property type="nucleotide sequence ID" value="XM_028671205.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVM5"/>
    <dbReference type="GeneID" id="39730994"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00246600"/>
    <dbReference type="OMA" id="KHCRTEK"/>
    <dbReference type="OrthoDB" id="1938138at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000811">
        <property type="term" value="C:GINS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11712">
        <property type="entry name" value="GINS_A_psf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021151">
        <property type="entry name" value="GINS_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036224">
        <property type="entry name" value="GINS_bundle-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007257">
        <property type="entry name" value="GINS_Psf2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12772">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12772:SF0">
        <property type="entry name" value="DNA REPLICATION COMPLEX GINS PROTEIN PSF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05916">
        <property type="entry name" value="Sld5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158573">
        <property type="entry name" value="GINS helical bundle-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GINS subunit" evidence="5">
        <location>
            <begin position="337"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="487" mass="58215" checksum="8942A0E154B88508" modified="2017-02-15" version="1">MDDIFSIFKKKHKAKKRASNTDRIENKNETKSLFNLNKKTQRRAHNEDDSLNYYNKYDKTTKDKIYNDIENTITIEFPPLPCKNSELCVSFYYIQYLRNQLIYGNKNIKIDENTKMIAESLLDKIENHIYELEFNKNNEEKNKNEIKIVIFKAIYDRYYKIFTTFIAYSEIIPLPNNLYQYVLNNGVYIRSKKSNDFNSRENIHNIYSYLDNIEVGDNDLSVNNEKIYIDNIDISRPTIINKSLINIDIDIEYLPLKFNSSYYYNNIQYAKLFLNDAINMSLYDKALGELIVVKALVDIPFGFEIKEMKAGERQWMPIYLAIFLSSFTYVDVEFPFWFYIKNFINIKEEEYKNPNELFELPSPYFFEICFMFIDQKIFSKATPIETVGQKSFFKYIAKVAGYIEDIKHCRAEKIIKHLEEQNVHSTHIYIKNLQYSETYLINLSLYSFWKYDEYINEKVNNIDFTSYLLEPFIKEDSDNDENVLQDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW40</accession>
    <name>A0A1J1GW40_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00412200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000062">
        <property type="protein sequence ID" value="CRG96540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529345.1">
        <property type="nucleotide sequence ID" value="XM_028672831.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW40"/>
    <dbReference type="GeneID" id="39732652"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00412200"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3030.10">
        <property type="entry name" value="Gametocyte protein Pfg27"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036469">
        <property type="entry name" value="Pfg27_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="401" mass="47487" checksum="8A41369659FCC1AE" modified="2017-02-15" version="1">MNILKAFNFYIILLVPYFIIFILDFRLLRKSFNHILQIDYHEMKLISQRSLAESIPYVREFYSKTKDDDTFLEKDNFIIKFPYSEYLLSQELFFKVNSENYSIEQATNDMESMLEKINSRFYFEGITLPLREMFNILNRMIERVMELPIESRMTRENLLQKIFELEKCATEELLKSLITSDEEVKYNIKDNMDKILDLVRRKLSLQNITLSDSVITKIATRISQSVDSAVIVYNEKFKNAPWKNEEYVQLYSNLHYEVMKDLLDIIYSKDYSHTARDVFFDSKLIMQTINGIAKKNNILLSYAQLRNMFIRVKECIRLTSLESISKSRISNMLKIFLLESDLVYEIAMQILNSGVQEDDIEYIAMTKAKTDNLLESQNIPLPEDVEQMAYRIKIYVSDIIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW52</accession>
    <name>A0A1J1GW52_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Elongation factor 1-alpha, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00265000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528056.1">
        <property type="nucleotide sequence ID" value="XM_028671400.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW52"/>
    <dbReference type="GeneID" id="39731179"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00265000"/>
    <dbReference type="OrthoDB" id="407705at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03705">
        <property type="entry name" value="EF1_alpha_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000005">
        <property type="entry name" value="Elongation factor 1-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054696">
        <property type="entry name" value="GTP-eEF1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44830">
        <property type="entry name" value="ELONGATION FACTOR 1 ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44830:SF1">
        <property type="entry name" value="TR-TYPE G DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22594">
        <property type="entry name" value="GTP-eEF1A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GTP-eEF1A C-terminal" evidence="6">
        <location>
            <begin position="46"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF22594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="168" mass="18343" checksum="3D09F65B3AD5AD30" modified="2017-02-15" version="1">MHKEVLEEARPGDNIGFNVKNVSVKEIKRGYVASDTKNEPAKGCAKFTAQVIILNHPGEIKNGYTPVLDCHTSHISCKFVNIDSKIDKRSGKVVEENPKAIKSGDSALVSLEPKKPMVVETFTEYPPLGRFAIRDMRQTIAVGIIKSVEKKEPGAVSSNKPAKTGAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW70</accession>
    <name>A0A1J1GW70_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00415200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529377.1">
        <property type="nucleotide sequence ID" value="XM_028672868.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732683"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00415200"/>
    <dbReference type="OMA" id="YVEYKII"/>
    <dbReference type="OrthoDB" id="378254at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1185"/>
            <end position="1221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1248"/>
            <end position="1271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1379"/>
            <end position="1404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1450"/>
            <end position="1476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2125"/>
            <end position="2152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1201"/>
            <end position="1220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1259"/>
            <end position="1268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1382"/>
            <end position="1404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2765" mass="331613" checksum="3B32A80E98E12EAD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW90</accession>
    <name>A0A1J1GW90_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Prefoldin subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00417000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the prefoldin subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529393.1">
        <property type="nucleotide sequence ID" value="XM_028672885.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW90"/>
    <dbReference type="GeneID" id="39732701"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00417000"/>
    <dbReference type="OMA" id="KFGRAIN"/>
    <dbReference type="OrthoDB" id="10250441at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002777">
        <property type="entry name" value="PFD_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016661">
        <property type="entry name" value="PFDN4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21100">
        <property type="entry name" value="PREFOLDIN SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21100:SF9">
        <property type="entry name" value="PREFOLDIN SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01920">
        <property type="entry name" value="Prefoldin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016477">
        <property type="entry name" value="Prefoldin_subunit_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="90"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR016477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="129" mass="15175" checksum="A627E75F9EA4E430" modified="2017-02-15" version="1">MSDIKDTKYDLGLDMTVDDQKKIGKFTNLHYKQSVYEQKIKLMKENLTNLDSSIDEVSLLFDSKDVMLNIGDCFFRFDTDYVEESLTEFKNEEKENLSKLEADYKTTLNEKQQLKTDLYAKFGNRIDLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWA5</accession>
    <name>A0A1J1GWA5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytochrome c oxidase subunit 5B, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">COX5B</name>
        <name evidence="3" type="ORF">PGAL8A_00440600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529628.1">
        <property type="nucleotide sequence ID" value="XM_028673146.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWA5"/>
    <dbReference type="GeneID" id="39732939"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00440600"/>
    <dbReference type="OMA" id="TERVVCC"/>
    <dbReference type="OrthoDB" id="10249250at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005740">
        <property type="term" value="C:mitochondrial envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045277">
        <property type="term" value="C:respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00924">
        <property type="entry name" value="Cyt_c_Oxidase_Vb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.11.10:FF:000005">
        <property type="entry name" value="Cytochrome c oxidase subunit 5b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.11.10">
        <property type="entry name" value="Cytochrome c oxidase, subunit Vb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002124">
        <property type="entry name" value="Cyt_c_oxidase_su5b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036972">
        <property type="entry name" value="Cyt_c_oxidase_su5b_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10122:SF0">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 5B, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10122">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 5B, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01215">
        <property type="entry name" value="COX5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57802">
        <property type="entry name" value="Rubredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51359">
        <property type="entry name" value="COX5B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="278" mass="32836" checksum="12D8AC2147FA2A40" modified="2017-02-15" version="1">MNFGRIIKNFSCKKIENIGKRSISNYCDKTKYNKLYRNENLYLKNIQKRTYLHFARTLPEDYELPLDTFPENISEILKKDKKSLDFIQSYWYWKIRSESNLLNYEKLIKKSYKQLAIDMGMQIANPDNEHMLALLEFYEYLKSSPFVGPFGTIENPVIVPSVHTERVVCCTGGTGENEHVPLFFRCREGFLYRCGECDQIFMHVRVLYSLSDGNDPFPNDPDVDDVFDLNLIEENMRLYNDDQYVRWPTGNVTYRQMFLEGKWGNEKPNNISNLSLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWH1</accession>
    <name>A0A1J1GWH1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00437000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529591.1">
        <property type="nucleotide sequence ID" value="XM_028673105.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWH1"/>
    <dbReference type="GeneID" id="39732902"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00437000"/>
    <dbReference type="OMA" id="DDICQYI"/>
    <dbReference type="OrthoDB" id="385030at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="590" mass="70833" checksum="18A1789D79CE20C5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWK4</accession>
    <name>A0A1J1GWK4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">T-complex protein 1 subunit gamma</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">CCT3</name>
        <name evidence="10" type="ORF">PGAL8A_00451100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529734.1">
        <property type="nucleotide sequence ID" value="XM_028673263.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWK4"/>
    <dbReference type="GeneID" id="39733044"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00451100"/>
    <dbReference type="OMA" id="DKMLVNP"/>
    <dbReference type="OrthoDB" id="10248520at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005832">
        <property type="term" value="C:chaperonin-containing T-complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03337">
        <property type="entry name" value="TCP1_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.560.10:FF:000085">
        <property type="entry name" value="T-complex protein 1 subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000005">
        <property type="entry name" value="T-complex protein 1 subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012719">
        <property type="entry name" value="Chap_CCT_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053374">
        <property type="entry name" value="TCP-1_chaperonin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054827">
        <property type="entry name" value="thermosome_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02344">
        <property type="entry name" value="chap_CCT_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041082">
        <property type="entry name" value="thermosome_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF041083">
        <property type="entry name" value="thermosome_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG96931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="543" mass="60678" checksum="E2F2ABFBA1B7BF66" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWV1</accession>
    <name>A0A1J1GWV1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Exosome complex exonuclease RRP41, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">RRP41</name>
        <name evidence="3" type="ORF">PGAL8A_00299300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNase PH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528589.1">
        <property type="nucleotide sequence ID" value="XM_028671992.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWV1"/>
    <dbReference type="GeneID" id="39731526"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00299300"/>
    <dbReference type="OMA" id="ECRINTH"/>
    <dbReference type="OrthoDB" id="27298at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071051">
        <property type="term" value="P:poly(A)-dependent snoRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050080">
        <property type="entry name" value="RNase_PH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11953:SF0">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="2">
        <location>
            <begin position="21"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="246" mass="27901" checksum="65C150B6806EC110" modified="2017-02-15" version="1">MSIQEYINEEGYRIDGRKSNECRLIKIHLGNENIFTDEDGFAFFEIGNTKILSYVQGPTELKKSDDKCSIKCEVFLSPFSVYEKRKKKTKDNITNEISAYVRNICENIILLDLYKNSEINIFLYIIERDGGLKHAAINTCLLALIDAGIAIKYFISSCSVLYLQNTMIVDANQLEINSGSPELTLVIELNTHKIILLEFDAEVPIDIFESMVKTCIECCIHLGNIMKLTVKENAIKLLSLNNILNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX20</accession>
    <name>A0A1J1GX20_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Hyaluronan/mRNA-binding protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00456800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529791.1">
        <property type="nucleotide sequence ID" value="XM_028673328.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX20"/>
    <dbReference type="GeneID" id="39733101"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00456800"/>
    <dbReference type="OMA" id="TGKFNWG"/>
    <dbReference type="OrthoDB" id="373812at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006861">
        <property type="entry name" value="HABP4_PAIRBP1-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04774">
        <property type="entry name" value="HABP4_PAI-RBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hyaluronan/mRNA-binding protein" evidence="2">
        <location>
            <begin position="13"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="71" mass="8030" checksum="A05F925F9D83A299" modified="2017-02-15" version="1">MANSNKDKNIRLERHSAGKTPAYGDSSVRAGTGKFNWGNTTDISLTEQKPIDQKDPMYDSDNEKNNREEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX49</accession>
    <name>A0A1J1GX49_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Osmiophilic body protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">G377</name>
        <name evidence="3" type="ORF">PGAL8A_00471000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529932.1">
        <property type="nucleotide sequence ID" value="XM_028673484.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733243"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00471000"/>
    <dbReference type="OMA" id="DHHNHHI"/>
    <dbReference type="OrthoDB" id="391720at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40201:SF1">
        <property type="entry name" value="AP-3 COMPLEX SUBUNIT DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40201">
        <property type="entry name" value="OSMIOPHILIC BODY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012227315" evidence="2">
        <location>
            <begin position="20"/>
            <end position="2527"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="603"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1136"/>
            <end position="1210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2527" mass="301992" checksum="8F902766334A16B4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXF4</accession>
    <name>A0A1J1GXF4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00318600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528781.1">
        <property type="nucleotide sequence ID" value="XM_028672206.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXF4"/>
    <dbReference type="GeneID" id="39731719"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00318600"/>
    <dbReference type="OMA" id="DAYMAQD"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="152" mass="18285" checksum="EF94E0BDD88C57D1" modified="2017-02-15" version="1">MNIEYVEGSDINELIKKIDINYKECEKYDIFIEENNIDEEKESFNNLKFRKKKNDIKNFETKNLNNNHDDKNEIKKGIDNIKNIIFQKKINDKNKKYVNFKKVNNKNVLTNLNVRKKRILESSDDESDENEFSSSVKTIVDYVKKRKNQRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXH9</accession>
    <name>A0A1J1GXH9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Protein transport protein SEC13, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00452400</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat SEC13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529747.1">
        <property type="nucleotide sequence ID" value="XM_028673278.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXH9"/>
    <dbReference type="GeneID" id="39733057"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00452400"/>
    <dbReference type="OMA" id="MNDKPHN"/>
    <dbReference type="OrthoDB" id="364224at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030127">
        <property type="term" value="C:COPII vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031080">
        <property type="term" value="C:nuclear pore outer ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090114">
        <property type="term" value="P:COPII-coated vesicle budding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000655">
        <property type="entry name" value="Protein transport protein SEC13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037363">
        <property type="entry name" value="Sec13/Seh1_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11024">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN SEC13 / SEH1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11024:SF2">
        <property type="entry name" value="PROTEIN SEC13 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="9" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="434"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="510"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="434"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="455"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="517"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="535"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="580"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="657"/>
            <end position="667"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG96944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="757" mass="84744" checksum="70AB36C95053257D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXL2</accession>
    <name>A0A1J1GXL2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">WD repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00488500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530108.1">
        <property type="nucleotide sequence ID" value="XM_028673680.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXL2"/>
    <dbReference type="GeneID" id="39733418"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00488500"/>
    <dbReference type="OMA" id="EYFMFCP"/>
    <dbReference type="OrthoDB" id="10261640at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051179">
        <property type="entry name" value="WD_repeat_multifunction"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857:SF8">
        <property type="entry name" value="ANGIO-ASSOCIATED MIGRATORY CELL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857">
        <property type="entry name" value="MITOCHONDRIAL DIVISION PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="516" mass="61742" checksum="BDF6E274F2815C7E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXQ0</accession>
    <name>A0A1J1GXQ0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00459600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529819.1">
        <property type="nucleotide sequence ID" value="XM_028673359.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXQ0"/>
    <dbReference type="GeneID" id="39733129"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00459600"/>
    <dbReference type="OMA" id="IWYLTSE"/>
    <dbReference type="OrthoDB" id="443257at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="265"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="403"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="555"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="319"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="275"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="406"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="555"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="574"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="616"/>
            <end position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="626" mass="73829" checksum="F0CBBB125C251644" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXW0</accession>
    <name>A0A1J1GXW0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methyltransferase, putative</fullName>
            <ecNumber evidence="4">2.1.1.61</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00487200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.61" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530095.1">
        <property type="nucleotide sequence ID" value="XM_028673665.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXW0"/>
    <dbReference type="GeneID" id="39733405"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00487200"/>
    <dbReference type="OMA" id="NNWAILL"/>
    <dbReference type="OrthoDB" id="271595at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106335">
        <property type="term" value="F:tRNA (5-carboxymethyluridine(34)-5-O)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004808">
        <property type="term" value="F:tRNA (5-methylaminomethyl-2-thiouridylate)(34)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000489">
        <property type="entry name" value="Methyltransferase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051422">
        <property type="entry name" value="AlkB_tRNA_MeTrf/Diox"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13069">
        <property type="entry name" value="ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13069:SF21">
        <property type="entry name" value="ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="3">
        <location>
            <begin position="384"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="571" mass="67756" checksum="78F46CE0A822C8B9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXW9</accession>
    <name>A0A1J1GXW9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA dimethylallyltransferase</fullName>
            <ecNumber evidence="3">2.5.1.75</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00490700</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>adenosine(37) in tRNA + dimethylallyl diphosphate = N(6)-dimethylallyladenosine(37) in tRNA + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:26482"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10375"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74415"/>
            <dbReference type="EC" id="2.5.1.75"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the IPP transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.75" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530130.1">
        <property type="nucleotide sequence ID" value="XM_028673704.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXW9"/>
    <dbReference type="GeneID" id="39733440"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00490700"/>
    <dbReference type="OMA" id="IKMRNHK"/>
    <dbReference type="OrthoDB" id="775260at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052381">
        <property type="term" value="F:tRNA dimethylallyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00185">
        <property type="entry name" value="IPP_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039657">
        <property type="entry name" value="Dimethylallyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018022">
        <property type="entry name" value="IPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00174">
        <property type="entry name" value="miaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11088">
        <property type="entry name" value="TRNA DIMETHYLALLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11088:SF60">
        <property type="entry name" value="TRNA DIMETHYLALLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01715">
        <property type="entry name" value="IPPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="281"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG97328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="508" mass="61460" checksum="B4A542D4C82A8903" modified="2017-02-15" version="1">MFCNLYIYIIYFFLIILLCFKTSSILIDCFIIKNKNIILTKEKKIYKIKLKNYNIFSSFKRKRNYTYPIYYNYKLQYPFNNNVLSKNKKKFIDKIFYPKKKRKNVMYLCKGNFTKKTGLMLYDKNKNMDDEYKLTEYKNENKNISEDDRIINPNFYKYGNNKKKKEKIILIIGVTCSGKTKFSIDLSEELLKYNIHSEIISSDSMQVYQNFNIGIAKINEEEKRDIKHHLLDICHHNDTFNVHKFINYTIPIIKNINYNNKLAIITGGTLLYIESLLWESVIDLKDEKDKKKEKHEQECEKDNYEDKTNDELYEKLKEVDEERANQLHKNDRKRICRSLDIFYTYNKKHSELIKIKNHKNNKLDEMRYIPCFFYLDYDNDDTLKKEIEKRVDLMISKGLLDEVIKLKELNKNRNIKASYKGINQSIAYKEFDAYIEKKINKINDDNLFNVCKDNLIRKTYKYAKKQRRWIFNRFVKTYHIPLNKIDVTKNYKEQLSESVHTILKFLHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY15</accession>
    <name>A0A1J1GY15_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Merozoite surface protein 3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00473500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000084">
        <property type="protein sequence ID" value="CRG97152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529955.1">
        <property type="nucleotide sequence ID" value="XM_028673509.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY15"/>
    <dbReference type="GeneID" id="39733268"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00473500"/>
    <dbReference type="OMA" id="KHAFNSA"/>
    <dbReference type="OrthoDB" id="392935at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0477">Merozoite</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="300"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="337"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="435"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="506"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="542"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="585"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="616" mass="68468" checksum="0B7EA62D3C9A51EE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYA9</accession>
    <name>A0A1J1GYA9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00504500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530273.1">
        <property type="nucleotide sequence ID" value="XM_028673862.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733578"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00504500"/>
    <dbReference type="OrthoDB" id="378159at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061574">
        <property type="term" value="C:ASAP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052793">
        <property type="entry name" value="EJC-associated_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46589">
        <property type="entry name" value="APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46589:SF1">
        <property type="entry name" value="APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="2427"/>
            <end position="2444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="2464"/>
            <end position="2482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="4693"/>
            <end position="4715"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="362"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="656"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1290"/>
            <end position="1808"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3715"/>
            <end position="3741"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="4551"/>
            <end position="4573"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="964"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2184"/>
            <end position="2218"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="4007"/>
            <end position="4088"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="362"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="656"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1290"/>
            <end position="1340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1341"/>
            <end position="1353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1354"/>
            <end position="1365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1372"/>
            <end position="1400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1401"/>
            <end position="1652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1660"/>
            <end position="1777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="3723"/>
            <end position="3732"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="5012" mass="604013" checksum="CDA827BF2925A52A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYD7</accession>
    <name>A0A1J1GYD7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribosome biogenesis regulatory protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00351400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in ribosomal large subunit assembly.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the RRS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529101.1">
        <property type="nucleotide sequence ID" value="XM_028672561.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYD7"/>
    <dbReference type="GeneID" id="39732044"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00351400"/>
    <dbReference type="OMA" id="FVHEYKP"/>
    <dbReference type="OrthoDB" id="28455at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007023">
        <property type="entry name" value="Ribosom_reg"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04939">
        <property type="entry name" value="RRS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="140"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="245" mass="29638" checksum="DAD37C0A951A5123" modified="2017-02-15" version="1">MDIEFCPQHLLAYDNSVINEEDDIKIKVEENLSSIIKKINELKNEKHNDGELIYFLEKNNFFNIPRYSKIPKTKKSTKWEMFAEKKLMKKKNKSGLIFDKNSKGWVRRYQKKHIKENEEKLKFVHEYKDNENLYEDPFEKKEEEKEIKKMKQKMREMKNKFDQKGISNEDIKYIQRQKRKRENLIDNLKMAQISSSTFGREDKKLKKEKKLKVKNNVTKQKYENRLPKDEINQNNKIAAIVLKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYF0</accession>
    <name>A0A1J1GYF0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Type I signal peptidase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00516700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase S26 family. IMP1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530395.1">
        <property type="nucleotide sequence ID" value="XM_028673998.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYF0"/>
    <dbReference type="GeneID" id="39733700"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00516700"/>
    <dbReference type="OMA" id="DSRNYGC"/>
    <dbReference type="OrthoDB" id="308440at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042720">
        <property type="term" value="C:mitochondrial inner membrane peptidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006627">
        <property type="term" value="P:protein processing involved in protein targeting to mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.109.10">
        <property type="entry name" value="Umud Fragment, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052064">
        <property type="entry name" value="Mito_IMP1_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000223">
        <property type="entry name" value="Pept_S26A_signal_pept_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019758">
        <property type="entry name" value="Pept_S26A_signal_pept_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12383:SF16">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12383">
        <property type="entry name" value="PROTEASE FAMILY S26 MITOCHONDRIAL INNER MEMBRANE PROTEASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10502">
        <property type="entry name" value="Peptidase_S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00727">
        <property type="entry name" value="LEADERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="LexA/Signal peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00761">
        <property type="entry name" value="SPASE_I_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S26" evidence="8">
        <location>
            <begin position="254"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR600223-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG97594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="319" mass="38093" checksum="909237C1FB6DD668" modified="2017-02-15" version="1">MIIYSHFIKSISFLKILQKKILYKNKVNYNTLGYNKANKRKYRLPNNNKIYMKNIKLNKNGLQSKNRVNLVRKYPSKKRNNNNFKINALNKKNFNINFTKIKYLLNFTKKITLCSLFIYAINNYFFDMTLTSGSSMHPLIDKNGVILFYICNDALKFFYKLHKIYIDSYIYILQKYNNIIKFMFRLNNIIYFNENISEKITNLKKKKEKSKHIYNRGDVVLLISPVNSNKRVCKRIIAIEKDKIYVDNFYSFIEIPKNNVWIEGDNKNDSFDSRNYGCVHVNLIVGKAFFLLDPFKSFSFINSKKNYQIESSRFLYLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYH9</accession>
    <name>A0A1J1GYH9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00509800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530326.1">
        <property type="nucleotide sequence ID" value="XM_028673922.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733631"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00509800"/>
    <dbReference type="OMA" id="IFANFQG"/>
    <dbReference type="OrthoDB" id="372022at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033489">
        <property type="entry name" value="RBBP6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15439:SF22">
        <property type="entry name" value="C3H1-TYPE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15439">
        <property type="entry name" value="RETINOBLASTOMA-BINDING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="319"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="359"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="424"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="466"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="503"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="534"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="782"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="975"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1006"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1176"/>
            <end position="1203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1223"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1265"/>
            <end position="1288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1300"/>
            <end position="1318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1325"/>
            <end position="1355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="618"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="618"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="653"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="674"/>
            <end position="684"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1501" mass="179154" checksum="4353AE6F7FE8113F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYN1</accession>
    <name>A0A1J1GYN1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Protein phosphatase PPM5, putative</fullName>
            <ecNumber evidence="8">3.1.3.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PPM5</name>
        <name evidence="8" type="ORF">PGAL8A_00525800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530483.1">
        <property type="nucleotide sequence ID" value="XM_028674096.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYN1"/>
    <dbReference type="GeneID" id="39733791"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00525800"/>
    <dbReference type="OMA" id="LPYMIIR"/>
    <dbReference type="OrthoDB" id="10264738at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47992">
        <property type="entry name" value="PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="7">
        <location>
            <begin position="118"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="217"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="231"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="493" mass="56517" checksum="3EE29D3ECE17CBAC" modified="2017-02-15" version="1">MGTCTSSIKKQTALKGDKNTRRRLSISTKSELPNDTEEIKRSIQELKENEDRFKESSENVIIERESTIKEKEKKVDKQKRNIKKRSSVAGVRASHFQEDFEKKCVKIKGSVDRLNQNGIGYVCRKGLKPESPNQDDFIIITMENLALYAIFDGHGPYGHDVSNYVQKELPYMIIKNENFLKNPKEVFTEAFLNIHESIEKTTNAYLESFANQNNNNPLGSDIYLNKHNDSSDEEDENDETDSDSYDNEDSDNCFEKKKSDETCKNDNEKENLIQKKEEKTLKKKKKKKKKIFFDSTMSGTTATIIVHLFKEKKLYIAYVGDSRAVLGKKKDGSNHLVAVELTKDHKPNSSGEKKRILNSGGQVIKLEGDIPYRVFIKNKFYPGLAMSRAIGDTIGHQIGIISEPDFIEVNINEEEDILVLICSDGVWEFISSEEAINLIYEFGYENVQDAVENLAKESWNRWLNEEENIVDDITIQAIYLSEKSKNQQKKNIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYR5</accession>
    <name>A0A1J1GYR5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00502800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530256.1">
        <property type="nucleotide sequence ID" value="XM_028673844.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYR5"/>
    <dbReference type="GeneID" id="39733561"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00502800"/>
    <dbReference type="OMA" id="RYDWMSS"/>
    <dbReference type="OrthoDB" id="378345at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="338" mass="40443" checksum="1B286189230BD30D" modified="2017-02-15" version="1">MLGKRKTNESQQKKRKKWIEELDDDLEEIDLECLNDLKENEKANIEEGLKEEEKEVSNNNLDEEKSNENLNELNDCVMHNENNKKRKRYEWMSSDDEDISSEDEENTNDEYDEDKIEENTDETKEDKNSENKDSENSTKSELSEKDKEKLNYINDNEKSNNKGNLKKNYEESDNKNNSLEIIDNINKYSINQLDIKLEDIEHIITYVYFNNIHFNCVTEKLVEFLENYTNNKIIQVNSDKSTNYTVLYKYDEKNNDKVTINNFSHYGKLFVHVKNYQDVLSLLKLNETQFMGRVIKSIQAYKKKNRFFILQAPSHYKYFIQVVINEKNKNNVNYVWMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYV2</accession>
    <name>A0A1J1GYV2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">40S ribosomal protein S16, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00522100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530446.1">
        <property type="nucleotide sequence ID" value="XM_028674055.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYV2"/>
    <dbReference type="GeneID" id="39733754"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00522100"/>
    <dbReference type="OMA" id="AHCKKGQ"/>
    <dbReference type="OrthoDB" id="426865at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000007">
        <property type="entry name" value="40S ribosomal protein S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000754">
        <property type="entry name" value="Ribosomal_uS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020574">
        <property type="entry name" value="Ribosomal_uS9_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001749">
        <property type="entry name" value="PRK00474.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569:SF16">
        <property type="entry name" value="RIBOSOMAL PROTEIN S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569">
        <property type="entry name" value="RIBOSOMAL PROTEIN S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00380">
        <property type="entry name" value="Ribosomal_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00360">
        <property type="entry name" value="RIBOSOMAL_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="144" mass="16387" checksum="3351551365933FE2" modified="2017-02-15" version="1">MTTKVKRVQTFGKKKTSVAVATVTNGKGLIKLNGKNLDLVEPYILRTKVYEPLWLIGSSKLKNLDIRIRVKGGGQTSQIYAIRQAIGKGIISYYQKYVDESTKKELKDILLRYDRTLLVGDTRRCEPKKFGGKGARARYQKSYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ20</accession>
    <name>A0A1J1GZ20_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">U4/U6 small nuclear ribonucleoprotein PRP3, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00505400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530282.1">
        <property type="nucleotide sequence ID" value="XM_028673873.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ20"/>
    <dbReference type="GeneID" id="39733587"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00505400"/>
    <dbReference type="OMA" id="CSLIWSG"/>
    <dbReference type="OrthoDB" id="10264544at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd24162">
        <property type="entry name" value="Prp3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013881">
        <property type="entry name" value="Pre-mRNA_splic_Prp3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027104">
        <property type="entry name" value="Prp3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010541">
        <property type="entry name" value="Prp3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14212">
        <property type="entry name" value="U4/U6-ASSOCIATED RNA SPLICING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14212:SF0">
        <property type="entry name" value="U4_U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08572">
        <property type="entry name" value="PRP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06544">
        <property type="entry name" value="Prp3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <feature type="domain" description="Pre-mRNA-splicing factor 3" evidence="7">
        <location>
            <begin position="167"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="Small nuclear ribonucleoprotein Prp3 C-terminal" evidence="6">
        <location>
            <begin position="503"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="406"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="412"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="658" mass="78127" checksum="82C50C6B1E5BDB91" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ62</accession>
    <name>A0A1J1GZ62_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nuclear protein localization protein 4, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00028800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530653.1">
        <property type="nucleotide sequence ID" value="XM_028674284.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ62"/>
    <dbReference type="GeneID" id="39728811"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00028800"/>
    <dbReference type="OMA" id="MYGYYKE"/>
    <dbReference type="OrthoDB" id="10251089at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08061">
        <property type="entry name" value="MPN_NPL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016563">
        <property type="entry name" value="Npl4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007717">
        <property type="entry name" value="NPL4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024682">
        <property type="entry name" value="Npl4_Ub-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12710">
        <property type="entry name" value="NUCLEAR PROTEIN LOCALIZATION 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12710:SF0">
        <property type="entry name" value="NUCLEAR PROTEIN LOCALIZATION PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05021">
        <property type="entry name" value="NPL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11543">
        <property type="entry name" value="UN_NPL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010052">
        <property type="entry name" value="Polyub_prc_Npl4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="2"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="490" mass="57156" checksum="88D27AE82E645D58" modified="2017-02-15" version="1">MTEIIVRLKCEIGLYRLEIDKNKKLIDLKKKIEEILNVPSEKQQLYLDEKPNVLLNNDFSILSECSIHNGSMILLKSEIKPNKKSNNNKDGANISNKEKDNSDYNEIRKKEAQKEVVSKGKDKDDKSDNKNESKSNFKSFDYFLKLRGYNTTDLPLNLTYKSIYLTKGKFIKIPLSITLKHQEYRHVDHLELMNVEEIKDFVHYWCYNNNMIEQRAGWMYGYYKEDSHYNLGIRAVCECIYEPPQINENNQVKFLPDEFLESVDLIAERLGLERIGWIFTHLPRKEYLTSDEVVHIAKLQLANMKKNMHYTNYSVSNFITCTISPDPLLSNEPVTNAFMVSDLGMALIRDNFIEENQMDPSHIHLRNPNKNELLPQILESGKETNKFDTDWFIVRVNESAPKVVRSIFRNFHFPRENRVNLQTANDIKEYFTSKKLDRGNNGNFKCSDFHLILFVSKVLDIETALALCDATLGKKEIDPIMEEVLTSIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ65</accession>
    <name>A0A1J1GZ65_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Splicing factor 3B subunit 4, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00517200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530400.1">
        <property type="nucleotide sequence ID" value="XM_028674004.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ65"/>
    <dbReference type="GeneID" id="39733705"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00517200"/>
    <dbReference type="OMA" id="YKPVWID"/>
    <dbReference type="OrthoDB" id="193499at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12347">
        <property type="entry name" value="RRM_PPIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034168">
        <property type="entry name" value="PPIE_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48038">
        <property type="entry name" value="RIBONUCLEOPROTEIN RB97D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48038:SF1">
        <property type="entry name" value="RIBONUCLEOPROTEIN RB97D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="6"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="123" mass="14524" checksum="5B1444DE790B40F9" modified="2017-02-15" version="1">MDDNAEIIFVGGIDETVDEKCLYDIFSSFGDIRNIEIPMNLVSKKNRGFAFIEYVEKDDAKHALYNMNNFEINGKRIYVNYSKTKKVDQYKPVWIDDLYNQEKMKLLEENSKEENLDKDNSFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ82</accession>
    <name>A0A1J1GZ82_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Maf-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00418900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529413.1">
        <property type="nucleotide sequence ID" value="XM_028672907.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ82"/>
    <dbReference type="GeneID" id="39732721"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00418900"/>
    <dbReference type="OMA" id="CRKSHDP"/>
    <dbReference type="OrthoDB" id="10267058at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047429">
        <property type="term" value="F:nucleoside triphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003697">
        <property type="entry name" value="Maf-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43213:SF4">
        <property type="entry name" value="7-METHYL-GTP PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43213">
        <property type="entry name" value="BIFUNCTIONAL DTTP/UTP PYROPHOSPHATASE/METHYLTRANSFERASE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02545">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="ITPase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="16"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="411" mass="48250" checksum="E927442D189B2BBB" modified="2017-02-15" version="1">MNEPNYKEYKTNNIYNKENELNNRNILKEEENIKNEDQLYNEFELEIDEEVISNLSFCVYNKNVNHKIIKVNNLIDSNLYNYIVNDKVYVEKEVNEISNNSLHFDNTKKNISVKNSSDELCNSVIEENQNTCICEEYDNLNKIEMMKCISEDINIYSNKKKNDVLFLCYDEKNDECDLCDRYRKNYMSNMQTLNSSNIKNLNDLNDYFFILGSTSNSRKYILKKNNLNFLSIHIKIDEKKIGCRKRHDPFTLTSNISIAKGLKLLSMIKNNIELKKKILELSKNKKLLLLVGDEVIYCNNKIYEKPKDKNEAYNFLKSYNNNKCFSYSSITLIDFITERIVTGIDESVIKICDMNDNIINKILDDLTIYFCAGALKIENTFMHKHIKEIKGNIDSIFGLSVNLLFHLVNFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0C3</accession>
    <name>A0A1J1H0C3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00431200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529536.1">
        <property type="nucleotide sequence ID" value="XM_028673044.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732844"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00431200"/>
    <dbReference type="OMA" id="NRIHYAY"/>
    <dbReference type="OrthoDB" id="6130531at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012656051" description="EGF-like domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="1572"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1532"/>
            <end position="1559"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="3">
        <location>
            <begin position="1357"/>
            <end position="1370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1572" mass="186832" checksum="A3F7F6D3DE316752" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0G3</accession>
    <name>A0A1J1H0G3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Glutamine synthetase, putative</fullName>
            <ecNumber evidence="9">6.3.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00435500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the glutamine synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.2" evidence="9"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529576.1">
        <property type="nucleotide sequence ID" value="XM_028673089.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0G3"/>
    <dbReference type="GeneID" id="39732887"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00435500"/>
    <dbReference type="OMA" id="PHPHEFE"/>
    <dbReference type="OrthoDB" id="77835at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamine synthetase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006542">
        <property type="term" value="P:glutamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.70">
        <property type="entry name" value="Glutamine synthetase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.590.10">
        <property type="entry name" value="Glutamine synthetase/guanido kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008147">
        <property type="entry name" value="Gln_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036651">
        <property type="entry name" value="Gln_synt_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027303">
        <property type="entry name" value="Gln_synth_gly_rich_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43785">
        <property type="entry name" value="GAMMA-GLUTAMYLPUTRESCINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43785:SF14">
        <property type="entry name" value="GLUTAMINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03951">
        <property type="entry name" value="Gln-synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54368">
        <property type="entry name" value="Glutamine synthetase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00181">
        <property type="entry name" value="GLNA_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51987">
        <property type="entry name" value="GS_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GS catalytic" evidence="8">
        <location>
            <begin position="112"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG96773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="542" mass="63081" checksum="B51DE05745E5DCB9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0K8</accession>
    <name>A0A1J1H0K8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00040900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG97980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530778.1">
        <property type="nucleotide sequence ID" value="XM_028674425.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0K8"/>
    <dbReference type="GeneID" id="39728934"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00040900"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006496">
        <property type="entry name" value="CHP01606_Plasmodium_spp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09688">
        <property type="entry name" value="Wx5_PLAF3D7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013153652" evidence="2">
        <location>
            <begin position="23"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="276" mass="32886" checksum="29810DF028AE2007" modified="2017-02-15" version="1">MKTLTLYLKITIFLLLIWMYHCFYNCDSNKTLVDKNILQTKNKLKYERLLTEGDIAGKKQSYGEECLEKCPLDNKKNKWKNPVLHENPYDHWNKVVTPFLRQEFNKETDGMDPKWREQKWNNEWNNISANNVNELSSIFDRSDISEEEKQKLIRSTKQELHIKFVKFLDECKKEIIGNKTESESKNDMTDNKTESESKNEMTHNKTESESKNEMTHNKTESESMNEMTDNKTESESKNEMTDNKTESESKNEKGKNKIKNKKSNIFKFFFKKFDNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0S9</accession>
    <name>A0A1J1H0S9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00471900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the p23/wos2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529941.1">
        <property type="nucleotide sequence ID" value="XM_028673494.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0S9"/>
    <dbReference type="GeneID" id="39733252"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00471900"/>
    <dbReference type="OMA" id="GDPNDCE"/>
    <dbReference type="OrthoDB" id="1564555at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051131">
        <property type="term" value="P:chaperone-mediated protein complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045250">
        <property type="entry name" value="p23-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22932:SF1">
        <property type="entry name" value="CO-CHAPERONE PROTEIN DAF-41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22932">
        <property type="entry name" value="TELOMERASE-BINDING PROTEIN P23 HSP90 CO-CHAPERONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012181811" description="CS domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="CS" evidence="3">
        <location>
            <begin position="22"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="183" mass="21643" checksum="D59543263774AB6A" modified="2017-02-15" version="1">MIKVLFFFLLLSTLFGSQSLQKQMPIIRWGQNSYQLTLIVSIPLIEKEEVKFNENNIYLSAISKHGEEYELNLNLLREIIPEKCSYALSELGLKLKVYKKAKEPCWIRLTKEQHKNNFLIKDKKLSDANDCEEAKDTWLENYKLYIRKNNPQNNEKPTKKNDIVQNIIENLKNVHPNFSLHEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0U0</accession>
    <name>A0A1J1H0U0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Microprotein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00447400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529696.1">
        <property type="nucleotide sequence ID" value="XM_028673222.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0U0"/>
    <dbReference type="GeneID" id="39733007"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00447400"/>
    <dbReference type="OMA" id="YIFMAGK"/>
    <dbReference type="OrthoDB" id="384245at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056324">
        <property type="entry name" value="Microp_apicomplexa_19"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23533">
        <property type="entry name" value="Microp_apicomplexa_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="Microprotein" evidence="2">
        <location>
            <begin position="44"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="140" mass="16116" checksum="FA0240A225A01668" modified="2017-02-15" version="1">MSGRNCFKNIFKNIFSKNTISKKSTNMTKVGKGVGGTMLLVSPILFELKHKEEENSPKSEYIFMAGKSIDFLTQKIFENEYGTSILYLVFFVAYLALLVHDNKVNLMVQKLKFKFSNNMFSVGHPNYKQYLPKNPLIKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0V9</accession>
    <name>A0A1J1H0V9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Macro domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00064200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028531000.1">
        <property type="nucleotide sequence ID" value="XM_028674671.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0V9"/>
    <dbReference type="GeneID" id="39729167"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00064200"/>
    <dbReference type="OrthoDB" id="365077at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="entry name" value="Leucine Aminopeptidase, subunit E, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053300">
        <property type="entry name" value="Homeobox-like_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002589">
        <property type="entry name" value="Macro_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45795">
        <property type="entry name" value="EARLY GAMETOCYTE ENRICHED PHOSPHOPROTEIN EGXP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45795:SF1">
        <property type="entry name" value="MACRO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01661">
        <property type="entry name" value="Macro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="Macro domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51154">
        <property type="entry name" value="MACRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="676"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="703"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="741"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="domain" description="Macro" evidence="3">
        <location>
            <begin position="298"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG98203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="792" mass="94893" checksum="1A9877317458EB29" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0Z6</accession>
    <name>A0A1J1H0Z6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Liver specific protein 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">LISP2</name>
        <name evidence="11" type="ORF">PGAL8A_00056000</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cell surface</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530922.1">
        <property type="nucleotide sequence ID" value="XM_028674584.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0Z6"/>
    <dbReference type="GeneID" id="39729085"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00056000"/>
    <dbReference type="OrthoDB" id="378063at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2860">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010884">
        <property type="entry name" value="6_CYS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038160">
        <property type="entry name" value="6_CYS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07422">
        <property type="entry name" value="s48_45"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00970">
        <property type="entry name" value="s48_45"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51701">
        <property type="entry name" value="6_CYS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="10">
        <location>
            <begin position="12"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="10">
        <location>
            <begin position="164"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="10">
        <location>
            <begin position="428"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="10">
        <location>
            <begin position="644"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="439"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="865"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="927"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1109"/>
            <end position="1137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="439"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="865"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="932"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="949"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="979"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1117"/>
            <end position="1137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG98125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1137" mass="133284" checksum="4AAD6833FC25FDF8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2C3</accession>
    <name>A0A1J1H2C3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nucleoplasmin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00522700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530452.1">
        <property type="nucleotide sequence ID" value="XM_028674061.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2C3"/>
    <dbReference type="GeneID" id="39733760"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00522700"/>
    <dbReference type="OMA" id="GCKSCTR"/>
    <dbReference type="OrthoDB" id="1902587at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.340">
        <property type="entry name" value="Nucleoplasmin core domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041232">
        <property type="entry name" value="NPL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17800">
        <property type="entry name" value="NPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleoplasmin-like" evidence="2">
        <location>
            <begin position="2"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="334" mass="38216" checksum="D111600C5C4F6741" modified="2017-02-15" version="1">MFYGKVIKAGETIIPEVKDGYSVIHISRACLNNPKEDGKVYVQVEDSKGCYNICCLQKNVCEDTSLDIFLMLDTDVKIKTSGSKNDVHIVGYYEVSFGQDNMDEDEDEFEDEDEYENEEVRMLTKKNTLKNSLSNGNAKKKKDVEDNEDDETNVGKNDEDDDDDEEDEDEKDKDDEDEDEDDDDDDDDDDEDGDDKDDDEDDEDEDEEDDEDEDDDEAEDAEEKEDEDDDGDEEEVTKSKGDKKKNEQKKSGGNKNKRALDNKNEGPSKKSKLDDESQYEKDLVAFLKKNGKSKLTELGKVKRPESVKVKLGFFIKKRTNVFKFDKDGQTVSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H308</accession>
    <name>A0A1J1H308_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00530300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530527.1">
        <property type="nucleotide sequence ID" value="XM_028674145.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733836"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00530300"/>
    <dbReference type="OMA" id="ESKNSHI"/>
    <dbReference type="OrthoDB" id="386851at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="617"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="678"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1371"/>
            <end position="1396"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="480"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="704"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1313"/>
            <end position="1340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="628"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="641"/>
            <end position="658"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1816" mass="212146" checksum="44303B1880CD4345" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2012-05-16" modified="2026-01-28" version="54" xmlns="https://uniprot.org/uniprot">
    <accession>H7CDZ2</accession>
    <name>H7CDZ2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">DNA-directed RNA polymerase subunit beta</fullName>
            <ecNumber evidence="4 14">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">rpoB</name>
        <name evidence="20" type="ORF">PGAL8A_API04300</name>
    </gene>
    <organism evidence="19">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <geneLocation type="apicoplast" evidence="19"/>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2012" name="Mol. Biol. Evol." volume="29" first="2095" last="2099">
            <title>The Plasmodium Apicoplast Genome: Conserved Structure and Close Relationship of P. ovale to Rodent Malaria Parasites.</title>
            <authorList>
                <person name="Arisue N."/>
                <person name="Hashimoto T."/>
                <person name="Mitsui H."/>
                <person name="Palacpac N.M.Q."/>
                <person name="Kaneko A."/>
                <person name="Kawai S."/>
                <person name="Hasegawa M."/>
                <person name="Tanabe K."/>
                <person name="Horii T."/>
            </authorList>
            <dbReference type="PubMed" id="22396524"/>
            <dbReference type="DOI" id="10.1093/molbev/mss082"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">A8</strain>
        </source>
    </reference>
    <reference evidence="20 21" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 14">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12 14">In plastids the minimal PEP RNA polymerase catalytic core is composed of four subunits: alpha, beta, beta', and beta''. When a (nuclear-encoded) sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Apicoplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="4 14"/>
    <dbReference type="EMBL" id="AB649424">
        <property type="protein sequence ID" value="BAL70762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LN835293">
        <property type="protein sequence ID" value="CRG98253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009325480.1">
        <property type="nucleotide sequence ID" value="NC_031963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="H7CDZ2"/>
    <dbReference type="GeneID" id="30315803"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_API04300"/>
    <dbReference type="OMA" id="FMTWEGY"/>
    <dbReference type="OrthoDB" id="35661at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Apicoplast API"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020011">
        <property type="term" value="C:apicoplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="entry name" value="DNA-directed RNA polymerase, subunit 2, domain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1800.10">
        <property type="entry name" value="RNA polymerase alpha subunit dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 19" id="KW-0933">Apicoplast</keyword>
    <keyword evidence="6 14 19" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 14" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7 19" id="KW-0934">Plastid</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 14" id="KW-0804">Transcription</keyword>
    <keyword evidence="8 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="97"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="141"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="18">
        <location>
            <begin position="330"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase subunit 2 hybrid-binding" evidence="16">
        <location>
            <begin position="533"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="17">
        <location>
            <begin position="935"/>
            <end position="1009"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00026088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU363031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="BAL70762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="CRG98253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1027" mass="123263" checksum="913B841D24FC83E1" modified="2012-05-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2012-07-11" modified="2026-01-28" version="53" xmlns="https://uniprot.org/uniprot">
    <accession>I2FKC7</accession>
    <name>I2FKC7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Isocitrate dehydrogenase [NADP]</fullName>
            <ecNumber evidence="10">1.1.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">IDH1</name>
        <name evidence="17" type="ORF">PGAL8A_00256800</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Gene" volume="502" first="36" last="39">
            <title>Age of the last common ancestor of extant Plasmodium parasite lineages.</title>
            <authorList>
                <person name="Hayakawa T."/>
                <person name="Tachibana S."/>
                <person name="Hikosaka K."/>
                <person name="Arisue N."/>
                <person name="Matsui A."/>
                <person name="Horii T."/>
                <person name="Tanabe K."/>
            </authorList>
            <dbReference type="PubMed" id="22555021"/>
            <dbReference type="DOI" id="10.1016/j.gene.2012.04.037"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19629"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="10 13">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="10 13">Binds 1 Mg(2+) or Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.42" evidence="10"/>
    <dbReference type="EMBL" id="AB571136">
        <property type="protein sequence ID" value="BAM15612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="I2FKC7"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00256800"/>
    <dbReference type="OMA" id="HGTVQRH"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004450">
        <property type="term" value="F:isocitrate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006097">
        <property type="term" value="P:glyoxylate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006102">
        <property type="term" value="P:isocitrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006739">
        <property type="term" value="P:NADP+ metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.718.10:FF:000002">
        <property type="entry name" value="Isocitrate dehydrogenase [NADP]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.718.10">
        <property type="entry name" value="Isopropylmalate Dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004790">
        <property type="entry name" value="Isocitrate_DH_NADP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00127">
        <property type="entry name" value="nadp_idh_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006156">
        <property type="entry name" value="PRK08299.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11822:SF21">
        <property type="entry name" value="ISOCITRATE DEHYDROGENASE [NADP], MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11822">
        <property type="entry name" value="NADP-SPECIFIC ISOCITRATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000108">
        <property type="entry name" value="IDH_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0329">Glyoxylate bypass</keyword>
    <keyword evidence="6 10 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 10 13" id="KW-0464">Manganese</keyword>
    <keyword evidence="5 10 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10" id="KW-0521">NADP</keyword>
    <keyword evidence="8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Isopropylmalate dehydrogenase-like" evidence="15">
        <location>
            <begin position="36"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="447"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="447"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>D-threo-isocitrate</name>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="121"/>
            <end position="127"/>
        </location>
        <ligand>
            <name>D-threo-isocitrate</name>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>D-threo-isocitrate</name>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>D-threo-isocitrate</name>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="site" description="Critical for catalysis" evidence="11">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <feature type="site" description="Critical for catalysis" evidence="11">
        <location>
            <position position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000108-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000108-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000108-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="BAM15612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="CRG95163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="466" mass="53241" checksum="0DF0D127DE751545" modified="2012-07-11" version="1">MVNKKVLKDNLFNIIKYNVHNNSAFNICGKIKVANPIVELDGDEMTRIIWKDIKDKLILPYLDLKIKYFDLSIQSRDKTNDEVTLEAAEEIKKHSVGIKCATITPDAARVKEFNLKQMWKSPNGTIRNILDGTVFRAPILIKNIPRLIPNWKKPIIIGRHAYADQYKQKSLKIDKTGKFEIVFTPDDNSGVIRETIFNFKSPGVCLGMYNTEESIRNFALSCFQYALDLKMPVYMSTKSTILKIYDGLFKDIFSEIYEEKFRKSFEQHNLWYEHKLIDDMVAQVLKSEGGFVWACKNYDGDIQSDAVAQGYGSLGLMSSILMCPDGVTCVAEAAHGTVTKHYRCYQKGQKTSTNPIASIFAWTRGLQQRAKLDNNQKLQQFCYALEKACIETVEDGLMSKDLAACIKGIKNVTEKDYLYTDDFIDAINEKLKLKLLVYQSKNDSQATTTKLNNDNWNHYAPQEHSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKR6</accession>
    <name>A0A1J1GKR6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chorein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00069600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG92992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525814.1">
        <property type="nucleotide sequence ID" value="XM_028673087.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729221"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00069600"/>
    <dbReference type="OrthoDB" id="383349at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031431">
        <property type="term" value="C:Dbf4-dependent protein kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043539">
        <property type="term" value="F:protein serine/threonine kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010571">
        <property type="term" value="P:positive regulation of nuclear cell cycle DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901987">
        <property type="term" value="P:regulation of cell cycle phase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051590">
        <property type="entry name" value="Replication_Regulatory_Kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15375">
        <property type="entry name" value="ACTIVATOR OF S-PHASE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15375:SF26">
        <property type="entry name" value="PROTEIN CHIFFON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="8076"/>
            <end position="8096"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="8117"/>
            <end position="8136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="8195"/>
            <end position="8221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2830"/>
            <end position="2850"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="4828"/>
            <end position="4849"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="6866"/>
            <end position="6885"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="7001"/>
            <end position="7030"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="4829"/>
            <end position="4845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="7014"/>
            <end position="7025"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG92992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="8278" mass="991374" checksum="2366923400629D31" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLB5</accession>
    <name>A0A1J1GLB5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00081900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525937.1">
        <property type="nucleotide sequence ID" value="XM_028670655.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLB5"/>
    <dbReference type="GeneID" id="39729343"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00081900"/>
    <dbReference type="OrthoDB" id="382651at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="274"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="426"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="454" mass="53310" checksum="5F83B0494B74895C" modified="2017-02-15" version="1">MNYPLKKKYLLNNYLPENILIRNFSKLKCKLFCNFSLNNYGYLKKDKLNKFKNIYYRKKGEMHIAYSKNYKWSKESNKKKKEYCEDQTSKKFLYYPESTSFPYGTICIVLGMVGVSTFLKILIYNLRNCDTEENILLQIDKILDYLDNYFIIYNSESNKKNINKSDIFDIKYLTSQFFTNENILQCSVQLSTFFLASRFLEKQYGSIRFLALFLTGSLLSILVSFYFFKYIKKVESLNFIDFVLIHPSGSMAFICALCSLCFKNSSIWKNIPVHCSILIVPYLFSSFYGLLSLYKIKKYNFIEESKENDANINENILLQNKDTILENKSEKNSPSNKVINITDDNVIKQKNDMNNKNKENYYNSNLIQKNENKVLNILKNFLIINACDSIIQKGKKENMFSNKRIINLKKEALKNINEINNKSQKIFFGLSSSFTDIFGIILASTTFLFLKFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLC5</accession>
    <name>A0A1J1GLC5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RGS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00070900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525827.1">
        <property type="nucleotide sequence ID" value="XM_028674532.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLC5"/>
    <dbReference type="GeneID" id="39729234"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00070900"/>
    <dbReference type="OMA" id="YYIFKHL"/>
    <dbReference type="OrthoDB" id="392728at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016137">
        <property type="entry name" value="RGS"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50132">
        <property type="entry name" value="RGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="305"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="344"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="RGS" evidence="2">
        <location>
            <begin position="525"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1280" mass="155717" checksum="2CCD94C8A6531B53" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLI5</accession>
    <name>A0A1J1GLI5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA (Cytosine-5)-methyltransferase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">DNMT</name>
        <name evidence="3" type="ORF">PGAL8A_00097600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526092.1">
        <property type="nucleotide sequence ID" value="XM_028672377.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLI5"/>
    <dbReference type="GeneID" id="39729500"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00097600"/>
    <dbReference type="OrthoDB" id="414133at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.120.10">
        <property type="entry name" value="DNA Methylase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050750">
        <property type="entry name" value="C5-MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46098">
        <property type="entry name" value="TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46098:SF1">
        <property type="entry name" value="TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="185"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="738" mass="88321" checksum="728497B915F7962A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLV6</accession>
    <name>A0A1J1GLV6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00103800</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526154.1">
        <property type="nucleotide sequence ID" value="XM_028673065.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729563"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00103800"/>
    <dbReference type="OMA" id="CELSEYI"/>
    <dbReference type="OrthoDB" id="371850at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050660">
        <property type="entry name" value="NEK_Ser/Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43671">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE NEK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43671:SF98">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE NEK11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 12" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1670"/>
            <end position="1690"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="1710"/>
            <end position="1729"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="2999"/>
            <end position="3286"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="3282"/>
            <end position="3637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="2683"/>
            <end position="2704"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG93332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3640" mass="441481" checksum="2498B8F2E0200129" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLW1</accession>
    <name>A0A1J1GLW1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">14-3-3 protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00111200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the 14-3-3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526228.1">
        <property type="nucleotide sequence ID" value="XM_028673888.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLW1"/>
    <dbReference type="GeneID" id="39729637"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00111200"/>
    <dbReference type="OMA" id="MIKNYRQ"/>
    <dbReference type="OrthoDB" id="10260625at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08774">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.190.20:FF:000001">
        <property type="entry name" value="14-3-3 gamma 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.190.20">
        <property type="entry name" value="14-3-3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000308">
        <property type="entry name" value="14-3-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023409">
        <property type="entry name" value="14-3-3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036815">
        <property type="entry name" value="14-3-3_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023410">
        <property type="entry name" value="14-3-3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18860">
        <property type="entry name" value="14-3-3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00244">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000868">
        <property type="entry name" value="14-3-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00305">
        <property type="entry name" value="1433ZETA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00101">
        <property type="entry name" value="14_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48445">
        <property type="entry name" value="14-3-3 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00796">
        <property type="entry name" value="1433_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00797">
        <property type="entry name" value="1433_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="14-3-3" evidence="4">
        <location>
            <begin position="11"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with phosphoserine on interacting protein" evidence="2">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with phosphoserine on interacting protein" evidence="2">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000868-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="262" mass="30265" checksum="E04AA62CA279BDA2" modified="2017-02-15" version="1">MATSEELKQLRCDCTYRSKLAEQAERYDEMAEAMRTLVEQCVNNDKDELTVEERNLLSVAYKNAVGARRASWRIISSVEQKEMSKANVHNKNVAATYRKKVEEELNNICQDILNLLTKKLIPNTSESESKVFYYKMKGDYYRYISEFSCDEGKKEASNFAQEAYQKATEIAENELPSTHPIRLGLALNYSVFFYEILNQPHQACEMAKRAFDDAITEFDNVSEDSYKDSTLIMQLLRDNLTLWTSDLQGDQTEEKSKDEGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM16</accession>
    <name>A0A1J1GM16_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00098300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526099.1">
        <property type="nucleotide sequence ID" value="XM_028672455.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM16"/>
    <dbReference type="GeneID" id="39729507"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00098300"/>
    <dbReference type="OrthoDB" id="2161449at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="648" mass="77952" checksum="AD5B13734F38D94F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMC5</accession>
    <name>A0A1J1GMC5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Crystalloid-specific PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00118900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526305.1">
        <property type="nucleotide sequence ID" value="XM_028674700.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMC5"/>
    <dbReference type="GeneID" id="39729714"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00118900"/>
    <dbReference type="OrthoDB" id="375723at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009618924" description="Crystalloid-specific PH domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="295" mass="34695" checksum="77B8B237772F4518" modified="2017-02-15" version="1">MKILSIIIIVSFISLCRSHRSFSKKNNYLQFLRSQNFIQEKPKYKKLNKNYSEDLNEFDDYEDEQTYNENEVGHMSNKQLNNNNLENYNNNNENKLDFKDIENELNNDELLRQDSNINLVRGGKECTINEKGIINVSIDSNDIFNLNKYNVEITSSNILIKDINDLKIIKSIPFKSIKLPIETIEETRECWNIKLNKEKILFCEQKKEDRDIWITNILKALFCYNTNNLMIEKSNTSNNESIHIPKESTVEERLKASKEGQDISNNNSPQYIKSSNYNNINISNLRNDEPKILFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="43" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GML4</accession>
    <name>A0A1J1GML4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transcription elongation factor SPT5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">SPT5</name>
        <name evidence="8" type="ORF">PGAL8A_00139400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the SPT5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526510.1">
        <property type="nucleotide sequence ID" value="XM_028674928.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GML4"/>
    <dbReference type="GeneID" id="39729918"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00139400"/>
    <dbReference type="OMA" id="QIFEVHE"/>
    <dbReference type="OrthoDB" id="28901at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032044">
        <property type="term" value="C:DSIF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06081">
        <property type="entry name" value="KOW_Spt5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09888">
        <property type="entry name" value="NGN_Euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.940">
        <property type="entry name" value="NusG, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041973">
        <property type="entry name" value="KOW_Spt5_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041975">
        <property type="entry name" value="KOW_Spt5_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041977">
        <property type="entry name" value="KOW_Spt5_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005100">
        <property type="entry name" value="NGN-domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036735">
        <property type="entry name" value="NGN_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039385">
        <property type="entry name" value="NGN_Euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005825">
        <property type="entry name" value="Ribosomal_uL24_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039659">
        <property type="entry name" value="SPT5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017071">
        <property type="entry name" value="TF_Spt5_eukaryote"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11125">
        <property type="entry name" value="SUPPRESSOR OF TY 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11125:SF7">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR SPT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23284">
        <property type="entry name" value="KOW2_Spt5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23291">
        <property type="entry name" value="KOW4_SPT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03439">
        <property type="entry name" value="Spt5-NGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036945">
        <property type="entry name" value="Spt5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01108">
        <property type="entry name" value="RIBOSOMAL_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="KOW" evidence="7">
        <location>
            <begin position="325"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="7">
        <location>
            <begin position="533"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="7">
        <location>
            <begin position="583"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="7">
        <location>
            <begin position="711"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="7">
        <location>
            <begin position="792"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="7">
        <location>
            <begin position="1091"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="42"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="973"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1051"/>
            <end position="1082"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="99"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="976"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="996"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1051"/>
            <end position="1079"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR036945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1198" mass="140771" checksum="43978DF9040D1A87" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMR3</accession>
    <name>A0A1J1GMR3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase I, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00133200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526449.1">
        <property type="nucleotide sequence ID" value="XM_028674860.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMR3"/>
    <dbReference type="GeneID" id="39729857"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00133200"/>
    <dbReference type="OMA" id="DEDKLHM"/>
    <dbReference type="OrthoDB" id="16820at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004462">
        <property type="term" value="F:lactoylglutathione lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019243">
        <property type="term" value="P:methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06587">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46036">
        <property type="entry name" value="LACTOYLGLUTATHIONE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46036:SF5">
        <property type="entry name" value="LACTOYLGLUTATHIONE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="50"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="304" mass="35717" checksum="2692F029FC6EB442" modified="2017-02-15" version="1">MKIFLVLIFSLFLKKYYFLNILKGKHNCFINKNNSFKKNKRYICRKLKCKLEGIEYKVQNLDASIDFYKNVLNFHISDKEKNFAKLTLGNDQAYIKLIQNEGNMNIGEHSFLGLGIKLNEFEINKTKLYKGNIEEQIEKRPITPCILPDEDAQIRKYWNNCFITDPDGYGIEIVLEKEENKLDRVRFFTTSTKDSQKFYTDILGMDLVKIQSHLEEISYPWNIYGGMSYFFSSKLNSTLLQFAYAYDEDKLHMGNSLGNLILSFKDLNEIEKKLNENNIEILKKGDDILVKDLNGYSVYLRKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GN21</accession>
    <name>A0A1J1GN21_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytosolic Fe-S cluster assembly factor NAR1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00142900</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NARF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526545.1">
        <property type="nucleotide sequence ID" value="XM_028674966.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GN21"/>
    <dbReference type="GeneID" id="39729953"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00142900"/>
    <dbReference type="OMA" id="LNFDYVY"/>
    <dbReference type="OrthoDB" id="10253113at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.20:FF:000042">
        <property type="entry name" value="Cytosolic Fe-S cluster assembly factor NAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1780">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.950.10">
        <property type="entry name" value="Fe-only Hydrogenase (Larger Subunit), Chain L, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050340">
        <property type="entry name" value="Cytosolic_Fe-S_CAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009016">
        <property type="entry name" value="Fe_hydrogenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004108">
        <property type="entry name" value="Fe_hydrogenase_lsu_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11615">
        <property type="entry name" value="NITRATE, FORMATE, IRON DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02906">
        <property type="entry name" value="Fe_hyd_lg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53920">
        <property type="entry name" value="Fe-only hydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Iron hydrogenase large subunit C-terminal" evidence="6">
        <location>
            <begin position="437"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="855" mass="101836" checksum="C16EDE971BD97689" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNK2</accession>
    <name>A0A1J1GNK2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fam-h protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00176900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526878.1">
        <property type="nucleotide sequence ID" value="XM_028670092.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNK2"/>
    <dbReference type="GeneID" id="39730296"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00176900"/>
    <dbReference type="OMA" id="CEQQDMI"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022139">
        <property type="entry name" value="Fam-L/Fam-M-like_plasmodium"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12420">
        <property type="entry name" value="DUF3671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="204"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="230" mass="27031" checksum="4058D40DE43E95B3" modified="2017-02-15" version="1">MRDYVNSNIILNSRRISHKEENFIIENSSTLKKYRTRGKINKLFFFIKISLFTLLIWILLYCENYNYRLWNDKYNLKNKLDLGSKRSLAEGKEVKEPTNEELKVSSSNMQTNLEENNTEVEKLELKEEEKDKKEIIKIENENENVVEKKRESNNKVNSLHLMQKYKKILRIFNIASIVLLPLMSMTLSIVAVSTNDKDNKYVSGSNIVTSLYLVLNSILLMDLKSNSNYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNL5</accession>
    <name>A0A1J1GNL5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Development protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00175700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526871.1">
        <property type="nucleotide sequence ID" value="XM_028670083.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730284"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00175700"/>
    <dbReference type="OMA" id="EYFYHKK"/>
    <dbReference type="OrthoDB" id="377778at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053097">
        <property type="entry name" value="Prespore_vesicle_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34586:SF3">
        <property type="entry name" value="FOLLISTATIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34586">
        <property type="entry name" value="SPERACT/SCAVENGER RECEPTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="933"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1181"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1022"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1397"/>
            <end position="1424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1022"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1399"/>
            <end position="1424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2102" mass="252356" checksum="AF52E3A3D3373FC1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNL7</accession>
    <name>A0A1J1GNL7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Bifunctional polynucleotide phosphatase/kinase, putative</fullName>
            <ecNumber evidence="1">2.7.1.78</ecNumber>
            <ecNumber evidence="1">3.1.3.32</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">PNKP</name>
        <name evidence="1" type="ORF">PGAL8A_00169600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.78" evidence="1"/>
    <dbReference type="EC" id="3.1.3.32" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526810.1">
        <property type="nucleotide sequence ID" value="XM_028670016.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNL7"/>
    <dbReference type="GeneID" id="39730223"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00169600"/>
    <dbReference type="OMA" id="AADWKWW"/>
    <dbReference type="OrthoDB" id="19045at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046404">
        <property type="term" value="F:ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046403">
        <property type="term" value="F:polynucleotide 3'-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006549">
        <property type="entry name" value="HAD-SF_hydro_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013954">
        <property type="entry name" value="PNK3P"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01662">
        <property type="entry name" value="HAD-SF-IIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12083">
        <property type="entry name" value="BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12083:SF9">
        <property type="entry name" value="BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08645">
        <property type="entry name" value="PNK3P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="462" mass="54940" checksum="390D28E4378C58F7" modified="2017-02-15" version="1">MKKRSISHFNLPNKKWNIVEDSLLYRIVKDKEDTIYKKIYSFDLDNTLILSRTYFKPAQNEYDYIFYSDNVIEFLKKKYSENYKIIIFSNQKGVSTGKISLLNIINRFDNIIDKIGIPLECYLALKNDKYRKPRIGMYNFAKQNNNHEIEEIIYVGDNANRIYDDNFKMIFINHLKYIYAKNNVKINIDEIYKKLKKDYTDTDLKFALNINATFYTPEELFLNLKNDISTNFSFEPRNLTKNVENINEFPYFIDQNKNEKKNEEKNEEKNEEKIDDIIGKEKKDIIPEFTKKNSKENDCQKLIILIGPPGCGKTFLCKNYFPYFIKISTIELKTKSKCLEALKESIIQGKSVIIDNVNKSVNDRLIYINEAKKINKNIKIEAIYFNYPKDLVFHLNAFKLITDKLNEIKDIPTISIHAFYKYVEDPTPKENYDKIIILNEKNFVPSKFENEEQKRLFFLYLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNM3</accession>
    <name>A0A1J1GNM3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00179100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000021">
        <property type="protein sequence ID" value="CRG94079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526900.1">
        <property type="nucleotide sequence ID" value="XM_028670116.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNM3"/>
    <dbReference type="GeneID" id="39730318"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00179100"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="153" mass="18239" checksum="5CB34AC90AC75140" modified="2017-02-15" version="1">MKTFTLYLKFFIFLLLIWIFHCFYNYDSSKSLVNKDKLQTKIGLKHERTLAEVDISEKKSSYIDKHTEHYTSGDMDIRLDEMVYLIGMYFKCYNANIKKDHAIDAFFKEENKMIYKCRDKILNAYRNIILSLMELEAFNGLISIVLGMKKEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNN0</accession>
    <name>A0A1J1GNN0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00171200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526826.1">
        <property type="nucleotide sequence ID" value="XM_028670034.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNN0"/>
    <dbReference type="GeneID" id="39730239"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00171200"/>
    <dbReference type="OMA" id="DANNYTY"/>
    <dbReference type="OrthoDB" id="383669at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050505">
        <property type="entry name" value="WDR55/POC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44019:SF8">
        <property type="entry name" value="POC1 CENTRIOLAR PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44019">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="154"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="155"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="425" mass="49889" checksum="6B37133F5E418A51" modified="2017-02-15" version="1">MNRALFYLSNHEDNIYSVKFFDENNLLSSCNCGLVTLWDLCKIKSIINFKVSNYSALYSNFFNNDKFFVKTKEGSLKIWDMNYDKCVTKLNTNNFTFAKPYSLNNQLVTPINHNGDIAICDINIKQNTSFNKDAFINDEFYNFNNIPLSNRSEVNDNNTFNKSDNNTFNKSDNNPFNKSDNNSFNKSDNNTFNKSDNKIYNNFNDYILTPGKTNTFNKLVISFKEIKKKIKNIEILSNKEDKDYEKFLNNNLNMFNEIIDIYPLKYFGETFILVCYEPSLFCIYDYRMTNNLISSFMLDMNKNVLSFNINNNNCIISTNNNFMYYLSFDKNQKIQLKKVVCNEYNNNQVVIRPDDQIFLSISNNSTINIYELNKIKLIDHISSYKFNHFNFLDFHNLSGFFAAAENSKISIWSNYANNFNSIKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNP2</accession>
    <name>A0A1J1GNP2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">60S ribosomal protein L7-2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00161000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526723.1">
        <property type="nucleotide sequence ID" value="XM_028675164.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNP2"/>
    <dbReference type="GeneID" id="39730135"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00161000"/>
    <dbReference type="OMA" id="CEYIFEC"/>
    <dbReference type="OrthoDB" id="28644at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.20">
        <property type="entry name" value="Ribosomal protein L30, ferredoxin-like fold domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036919">
        <property type="entry name" value="Ribo_uL30_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039699">
        <property type="entry name" value="Ribosomal_uL30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11524">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11524:SF16">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55129">
        <property type="entry name" value="Ribosomal protein L30p/L7e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="252" mass="30624" checksum="D5942A0B71CDC5AE" modified="2017-02-15" version="1">MNKSEITKEPKNKIGNNKIKRVKFRRVKKIKFKDEKILVEKRKSKVKKNKSKKKFDTIFKKKEYEKKLEKQKDEFYNLQKQWKNQNFDQEKSCIFVLRNDVDCIYNAPKKILQKLKLNNKYDGILLINTKKNMKILFIISPYICYGYIKKYNFYNLMEKRLFLKDDNNKIKRVNSNKIIEELFGKQGILSFSSLCDYIFECKENADLITKKYIMPFDFSFLNNKMTFDFLQFKNEFKGFMKEEINEILEKII</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNR3</accession>
    <name>A0A1J1GNR3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00382500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526942.1">
        <property type="nucleotide sequence ID" value="XM_028670162.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNR3"/>
    <dbReference type="GeneID" id="39732355"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00382500"/>
    <dbReference type="OrthoDB" id="375842at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013584">
        <property type="entry name" value="RAP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00952">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51286">
        <property type="entry name" value="RAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RAP" evidence="1">
        <location>
            <begin position="737"/>
            <end position="797"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="802" mass="95212" checksum="7B67AC3991C22C0C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNU3</accession>
    <name>A0A1J1GNU3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metallopeptidase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00385700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526974.1">
        <property type="nucleotide sequence ID" value="XM_028670197.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNU3"/>
    <dbReference type="GeneID" id="39732387"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00385700"/>
    <dbReference type="OMA" id="NELMITQ"/>
    <dbReference type="OrthoDB" id="261960at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2010.10">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013536">
        <property type="entry name" value="WLM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053000">
        <property type="entry name" value="WSS1-like_metalloprotease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46622">
        <property type="entry name" value="DNA-DEPENDENT METALLOPROTEASE WSS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46622:SF1">
        <property type="entry name" value="DNA-DEPENDENT METALLOPROTEASE WSS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08325">
        <property type="entry name" value="WLM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51397">
        <property type="entry name" value="WLM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WLM" evidence="1">
        <location>
            <begin position="4"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="341" mass="39733" checksum="5B6B52C983FB5745" modified="2017-02-15" version="1">MNIKTLDDLKYKIHKIKVLNENDKKAKSILRKAAEQVMPIMRKRRFSVELLSEFLPANPSLLGLNIAKNSEIKIRLRNKKGSELFHFNDIMGTLLHELAHIVHSRHDKSFYELLDKLILEYNELYAYKNLGYTGKKVGNSKNKSIFFNSNPKVMAAQAAEKRLMNNFINKDGKIINLSLESCLTEEQRENLFKSRTEYDDKICSVNNDVIIIDPVNNFYKNKENENFVNYMPTKKDKQLPTNSINTKYTVNCANSNNKNKNYLNSKMNINYINKKSYEDNFDDNPKRKAPVLNSYNDDSVHFLGAKKVDSDQKEVKNGNNSFFCDNFYINKNKKRKIIILD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNX9</accession>
    <name>A0A1J1GNX9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00389500</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nicastrin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527012.1">
        <property type="nucleotide sequence ID" value="XM_028670240.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNX9"/>
    <dbReference type="GeneID" id="39732425"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00389500"/>
    <dbReference type="OMA" id="GGCITAY"/>
    <dbReference type="OrthoDB" id="5913609at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009966">
        <property type="term" value="P:regulation of signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016574">
        <property type="entry name" value="Nicalin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31826">
        <property type="entry name" value="NICALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="568"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG94191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="599" mass="72457" checksum="192CE1F338A473D0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNY3</accession>
    <name>A0A1J1GNY3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">S-adenosylmethionine-dependent methyltransferase, putative</fullName>
            <ecNumber evidence="7">2.1.1.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00069500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.12" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG92991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525813.1">
        <property type="nucleotide sequence ID" value="XM_028672976.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNY3"/>
    <dbReference type="GeneID" id="39729220"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00069500"/>
    <dbReference type="OMA" id="KHYLVVQ"/>
    <dbReference type="OrthoDB" id="2877at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030732">
        <property type="term" value="F:methionine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016435">
        <property type="term" value="F:rRNA (guanine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070476">
        <property type="term" value="P:rRNA (guanine-N7)-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000364">
        <property type="entry name" value="S-adenosylmethionine-dependent methyltransferase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039769">
        <property type="entry name" value="Bud23-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022238">
        <property type="entry name" value="Bud23_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12734:SF0">
        <property type="entry name" value="18S RRNA (GUANINE-N(7))-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12734">
        <property type="entry name" value="METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12589">
        <property type="entry name" value="WBS_methylT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="6">
        <location>
            <begin position="52"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23 C-terminal" evidence="5">
        <location>
            <begin position="220"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="249"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="249"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG92991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="273" mass="31663" checksum="DD6F6C8049049B79" modified="2017-02-15" version="1">MVRPEYTSPPEIFYNEDEAKKYVRNSRIRDIQSKMTERALELLVLPDTPCLLLDIGCGSGISGMTLNESDHFWIGIDISIHMIRAGLQNEAHLGGEMILSDMGKLMRFQSCIFDGVVSISALQWLCNWDKKDENPIARINTFFKWLYNCLRKGARAVFQFYPDSAEQIETLTNFAMKSGFGGGVVVDFPNSAKSKKYYLCLWAGSSIIPKLPEAIKDEDEVISHEKRRFNKKTKKQIKKNKEWIMKKKEQRRMKGLEVKRDSKYTGRKRKRRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP69</accession>
    <name>A0A1J1GP69_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Prohibitin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00390900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the prohibitin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527026.1">
        <property type="nucleotide sequence ID" value="XM_028670256.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP69"/>
    <dbReference type="GeneID" id="39732439"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00390900"/>
    <dbReference type="OMA" id="VPFIQNP"/>
    <dbReference type="OrthoDB" id="275637at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03401">
        <property type="entry name" value="SPFH_prohibitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.479.30:FF:000001">
        <property type="entry name" value="Prohibitin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000163">
        <property type="entry name" value="Prohibitin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222">
        <property type="entry name" value="PROHIBITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222:SF1">
        <property type="entry name" value="PROHIBITIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00679">
        <property type="entry name" value="PROHIBITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="7">
        <location>
            <begin position="39"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="283" mass="32049" checksum="D1CD6187652754F0" modified="2017-02-15" version="1">MNNPHNFDINNLKKLGKIGISIGAVIGVTSFSSWLFKNSLYNVEAGKRAIKYNRIFGLSNKIYGEGTHFLIPYFERSIIYDVRTKPRVLMSLTGSRDLQMVNITCRVLSRPNEKKLVEIYRTLGKEYDEKVLPSIINEVLKSVVAQYNASQLITQREVVSKSVREQLVQRAKDFNILLDDASITHLSFSNEYEKAVEAKQVAQQEAERSKYIVLKAEQEKKSTIIKAQGEAEVAKLIGLAVKDNPAFMELKKIELSKEVSNIISKCQNKVMLSADSLLLNFVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPE5</accession>
    <name>A0A1J1GPE5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Dihydrolipoyl dehydrogenase, apicoplast, putative</fullName>
            <ecNumber evidence="15">1.8.1.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PGAL8A_00086300</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="9">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.4" evidence="15"/>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525981.1">
        <property type="nucleotide sequence ID" value="XM_028671144.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPE5"/>
    <dbReference type="GeneID" id="39729387"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00086300"/>
    <dbReference type="OrthoDB" id="361797at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045252">
        <property type="term" value="C:oxoglutarate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004148">
        <property type="term" value="F:dihydrolipoyl dehydrogenase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006103">
        <property type="term" value="P:2-oxoglutarate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.30:FF:000001">
        <property type="entry name" value="Dihydrolipoyl dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050151">
        <property type="entry name" value="Class-I_Pyr_Nuc-Dis_Oxidored"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22912:SF151">
        <property type="entry name" value="DIHYDROLIPOYL DEHYDROGENASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22912">
        <property type="entry name" value="DISULFIDE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="FAD/NAD-linked reductases, dimerisation (C-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 9 11" id="KW-0274">FAD</keyword>
    <keyword evidence="2 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 11 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7 11" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="14">
        <location>
            <begin position="115"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridine nucleotide-disulphide oxidoreductase dimerisation" evidence="13">
        <location>
            <begin position="509"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="629"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="280"/>
            <end position="282"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="317"/>
            <end position="324"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="340"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="416"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="462"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="468"/>
            <end position="471"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="10">
        <location>
            <begin position="154"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG93159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="649" mass="73738" checksum="981E1F8E34F41A39" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPG4</accession>
    <name>A0A1J1GPG4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00410000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527214.1">
        <property type="nucleotide sequence ID" value="XM_028670464.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPG4"/>
    <dbReference type="GeneID" id="39732630"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00410000"/>
    <dbReference type="OMA" id="CYSARRN"/>
    <dbReference type="OrthoDB" id="386016at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="90"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="121" mass="14924" checksum="50E0F12C6818567C" modified="2017-02-15" version="1">MIRYIFKSQNYNTIYFQFKKYNFNSTNFFKEIKYYYSSKKNEEQKEKLSKEANERDYLWNILAFDRNISFFSISFYILLVATLSLHFYNNMNENNKLNKVNEAIEREKKILTELQNKRKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPL1</accession>
    <name>A0A1J1GPL1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Proteasome assembly chaperone 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00183100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527260.1">
        <property type="nucleotide sequence ID" value="XM_028670515.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPL1"/>
    <dbReference type="GeneID" id="39730358"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00183100"/>
    <dbReference type="OMA" id="EPHSYGN"/>
    <dbReference type="OrthoDB" id="368507at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043248">
        <property type="term" value="P:proteasome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032157">
        <property type="entry name" value="PAC4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33559">
        <property type="entry name" value="PROTEASOME ASSEMBLY CHAPERONE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33559:SF1">
        <property type="entry name" value="PROTEASOME ASSEMBLY CHAPERONE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16093">
        <property type="entry name" value="PAC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="137" mass="15958" checksum="711227D6D094A244" modified="2017-02-15" version="1">MNEPCEYSENYSSTIQKGKECNVNVEIYRYHKIYMSYLNLYFCVIDFNETMFISVSDENNELNDLQASYPLKYEDADNTVCLVGEPNSYGNDVARLLGKKFKIPFYVSVNVDESDENLTNFIFSSCLDILKPIFENR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPR2</accession>
    <name>A0A1J1GPR2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00189700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000026">
        <property type="protein sequence ID" value="CRG94500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527318.1">
        <property type="nucleotide sequence ID" value="XM_028670580.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPR2"/>
    <dbReference type="GeneID" id="39730422"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00189700"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="115" mass="13975" checksum="1B7FAB7C8A99474F" modified="2017-02-15" version="1" fragment="single">HDHSRYFMNKYTLQIKNKLKDKRVLAEGDISEKKQTIIKEHKEYYPFGEKDNQVEKLVYFINIYSMLYNAFLLLIYELFSKKTNKMSNKCKEQISNVCRNNNSEPYYMTEFSLIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPR3</accession>
    <name>A0A1J1GPR3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Plasmodium RESA N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00180200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527234.1">
        <property type="nucleotide sequence ID" value="XM_028670486.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPR3"/>
    <dbReference type="GeneID" id="39730329"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00180200"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="276" mass="32407" checksum="A8F0CF0B5D6CA5DE" modified="2017-02-15" version="1">MNFYIESNISPKIPLAKSVVNNDHYSRYSYEEKEKSIKKRNFISIMSSKLFILSFFTLLYILLISIHKSYVKVGSDLKSCNIYSRKLAEFIPGLSKEEEELDVAEKLESMNLNDSSNNDPVVKPKKKSRNRGSRRQRRYLVSDKPLTEDEINDEIENLLECTFKKYAKLSTVIVDEHLEILDETSTKLNALYKRMKNSNSNEMKSKKDIWDCLDVDYFTEKAIKQQKENFKLLKELSENNSSNIQEISKHTRNIIETSYKMTKEMIELWKSIFTSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ62</accession>
    <name>A0A1J1GQ62_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00203600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527454.1">
        <property type="nucleotide sequence ID" value="XM_028670730.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ62"/>
    <dbReference type="GeneID" id="39730562"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00203600"/>
    <dbReference type="OMA" id="TICNYFY"/>
    <dbReference type="OrthoDB" id="379794at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="491" mass="59733" checksum="B69FC24B784C710D" modified="2017-02-15" version="1">MSLEKFDEFEIIEKHYNFKNNVKKLDENEEDKIIYLLIVCKNKIEVEKENKENLNNYIKALKILIFYIPFNDSLKKKITEKKIYKFLLLGKSFNISNNLSEEPCNNLNKSSNVSSVNKLNEYLIYEVDKYELIFLINLITHNEKNEEIFEFLYPSYVYYIILNKSNMDNIFMLLNNFIINRKTYELLNKLNDLSLLIFLSVIDSLKKIKNQINICNYFYVFIENSLKYENKLFLNIFENLKKLYTDFFEYIKKLKENFLFSNMLKKWKIINKKENKYYLLKYIALMFRLVLETLYNILDEKNLDNEQISKYQNLYRTIIEEIKNNLIYINEINYFDNFDISHIDLYNKNILFMDMFIYYRKNFILENFKLILFISNIFSDRYEELDYLSCEEKKNFIDIIFVYLKTISKMRNSHILEKQEILYHKFILNRYIISAVANFSSDNIISNYVKKINGIDVLRKFMYIDDKDTCLPEYSILAIKHIKENENFEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQD3</accession>
    <name>A0A1J1GQD3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00191000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000028">
        <property type="protein sequence ID" value="CRG94513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527329.1">
        <property type="nucleotide sequence ID" value="XM_028670592.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQD3"/>
    <dbReference type="GeneID" id="39730435"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00191000"/>
    <dbReference type="OMA" id="NIELFEI"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="320"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="499"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="159"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="499"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="510"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="573" mass="70073" checksum="445FD6EA14ED2C42" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQG8</accession>
    <name>A0A1J1GQG8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="5">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00099600</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="5">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526112.1">
        <property type="nucleotide sequence ID" value="XM_028672599.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729520"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00099600"/>
    <dbReference type="OMA" id="FFLHCPT"/>
    <dbReference type="OrthoDB" id="386952at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="906"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="1126"/>
            <end position="1296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="261"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="576"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1023"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="121"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG93290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1301" mass="155852" checksum="DAD9CB23B943A2EF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQR3</accession>
    <name>A0A1J1GQR3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">WD repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00227400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527692.1">
        <property type="nucleotide sequence ID" value="XM_028670995.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730801"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00227400"/>
    <dbReference type="OMA" id="YIHYYDN"/>
    <dbReference type="OrthoDB" id="372074at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031514">
        <property type="term" value="C:motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050630">
        <property type="entry name" value="WD_repeat_EMAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720:SF13">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 251"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13720">
        <property type="entry name" value="WD-40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1353"/>
            <end position="1373"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="574"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1089"/>
            <end position="1116"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1212"/>
            <end position="1239"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1274"/>
            <end position="1301"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1469"/>
            <end position="1524"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1606"/>
            <end position="1640"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1701"/>
            <end position="1799"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG94877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1820" mass="220783" checksum="924FF8DD9DB1FD8E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR27</accession>
    <name>A0A1J1GR27_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">SNARE protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">YKT6.2</name>
        <name evidence="11" type="ORF">PGAL8A_00236600</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endomembrane system</location>
            <topology evidence="7">Lipid-anchor</topology>
            <orientation evidence="7">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the synaptobrevin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527782.1">
        <property type="nucleotide sequence ID" value="XM_028671096.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR27"/>
    <dbReference type="GeneID" id="39730894"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00236600"/>
    <dbReference type="OMA" id="HYIGIIR"/>
    <dbReference type="OrthoDB" id="27923at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14824">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.50">
        <property type="entry name" value="Longin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010908">
        <property type="entry name" value="Longin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001388">
        <property type="entry name" value="Synaptobrevin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042855">
        <property type="entry name" value="V_SNARE_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45806">
        <property type="entry name" value="SYNAPTOBREVIN HOMOLOG YKT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45806:SF1">
        <property type="entry name" value="SYNAPTOBREVIN HOMOLOG YKT6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00957">
        <property type="entry name" value="Synaptobrevin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00219">
        <property type="entry name" value="SYNAPTOBREVN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01270">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50859">
        <property type="entry name" value="LONGIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50892">
        <property type="entry name" value="V_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0488">Methylation</keyword>
    <keyword evidence="4" id="KW-0564">Palmitate</keyword>
    <keyword evidence="6" id="KW-0636">Prenylation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Longin" evidence="9">
        <location>
            <begin position="23"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="V-SNARE coiled-coil homology" evidence="10">
        <location>
            <begin position="160"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00046278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG94969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="220" mass="25508" checksum="97B453685A932860" modified="2017-02-15" version="1">MVDSSNNVPYTENSNKIALYALLIYKYDISQPIFLSASFDLSSFPFFHRSSLKEHIYFHSRLVCSRTPRGNREVIELESGIGHLHIYTNSENNISVLVLSTPSYPLRIAFGLIDNTQKLFIEKCKGQYENITQDLKEGVLFNNELNELLKKYQNPSEADKLSKVQKDLDEVKDVMLKNIEDLLQRGEKLDDLMKKSQDLSNSSYQFYRQAKKNNQCCKLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR81</accession>
    <name>A0A1J1GR81_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00219900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527617.1">
        <property type="nucleotide sequence ID" value="XM_028670912.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730726"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00219900"/>
    <dbReference type="OMA" id="DTQILFY"/>
    <dbReference type="OrthoDB" id="387374at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="410"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="834"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1155"/>
            <end position="1181"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="31"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="417"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1156"/>
            <end position="1179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1381" mass="163668" checksum="88C5A5C004AD856F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRA0</accession>
    <name>A0A1J1GRA0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA sliding clamp PCNA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PCNA2</name>
        <name evidence="7" type="ORF">PGAL8A_00127700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processivity during elongation of the leading strand.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the PCNA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526392.1">
        <property type="nucleotide sequence ID" value="XM_028674797.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRA0"/>
    <dbReference type="GeneID" id="39729802"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00127700"/>
    <dbReference type="OMA" id="MDNSHIS"/>
    <dbReference type="OrthoDB" id="534348at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043626">
        <property type="term" value="C:PCNA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030337">
        <property type="term" value="F:DNA polymerase processivity factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006272">
        <property type="term" value="P:leading strand elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006275">
        <property type="term" value="P:regulation of DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019985">
        <property type="term" value="P:translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00577">
        <property type="entry name" value="PCNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.70.10.10:FF:000009">
        <property type="entry name" value="Proliferating cell nuclear antigen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.70.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00317">
        <property type="entry name" value="DNApol_clamp_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046938">
        <property type="entry name" value="DNA_clamp_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000730">
        <property type="entry name" value="Pr_cel_nuc_antig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022649">
        <property type="entry name" value="Pr_cel_nuc_antig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022659">
        <property type="entry name" value="Pr_cel_nuc_antig_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022648">
        <property type="entry name" value="Pr_cel_nuc_antig_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00590">
        <property type="entry name" value="pcna"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11352">
        <property type="entry name" value="PROLIFERATING CELL NUCLEAR ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11352:SF0">
        <property type="entry name" value="PROLIFERATING CELL NUCLEAR ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02747">
        <property type="entry name" value="PCNA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00705">
        <property type="entry name" value="PCNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00339">
        <property type="entry name" value="PCNACYCLIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55979">
        <property type="entry name" value="DNA clamp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01251">
        <property type="entry name" value="PCNA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Proliferating cell nuclear antigen PCNA N-terminal" evidence="5">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="Proliferating cell nuclear antigen PCNA C-terminal" evidence="6">
        <location>
            <begin position="133"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="264" mass="30172" checksum="84549E90B39913B8" modified="2017-02-15" version="1">MFECRIDGQFFKKLFETLKDICTEVNLECDENGIKMQSMDCSHVSLVDLNIVSDFFQHYRCDKNCVLGISINFMLKILSVIKEKSTVFLFKEDNENDAVLNIGIIDEEEQSSSDDSLEIQVKLINAQKEHLEIPQSEYHCQCTMKSKKFQEFTKYLNSIGDNVSISMKKDTMILSTTGSDIKVTKQFTNDMTDVSITCTKSVSQEFATRYLVMFSRASSLSDEVLISLSPNIPISIKFNFKQQIADLQENSHLTFFLAPKIGDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRC7</accession>
    <name>A0A1J1GRC7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ribonuclease Z</fullName>
            <ecNumber evidence="4">3.1.26.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00224700</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule.</text>
            <dbReference type="EC" id="3.1.26.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase Z family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.11" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527665.1">
        <property type="nucleotide sequence ID" value="XM_028670964.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRC7"/>
    <dbReference type="GeneID" id="39730774"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00224700"/>
    <dbReference type="OMA" id="INYICQL"/>
    <dbReference type="OrthoDB" id="527344at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042781">
        <property type="term" value="F:3'-tRNA processing endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990180">
        <property type="term" value="P:mitochondrial tRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07718">
        <property type="entry name" value="RNaseZ_ELAC1_ELAC2-C-term-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.15.10:FF:000078">
        <property type="entry name" value="Ribonuclease Z, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047151">
        <property type="entry name" value="RNZ2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027794">
        <property type="entry name" value="tRNase_Z_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12553">
        <property type="entry name" value="ZINC PHOSPHODIESTERASE ELAC PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12553:SF49">
        <property type="entry name" value="ZINC PHOSPHODIESTERASE ELAC PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23023">
        <property type="entry name" value="Anti-Pycsar_Apyc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13691">
        <property type="entry name" value="Lactamase_B_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="9 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNase Z endonuclease" evidence="12">
        <location>
            <begin position="29"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="186"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF13691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG94850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="806" mass="93591" checksum="919A2CBE352C6A06" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRD1</accession>
    <name>A0A1J1GRD1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mitochondrial fission 1 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">FIS1</name>
        <name evidence="4" type="ORF">PGAL8A_00237500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the FIS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527791.1">
        <property type="nucleotide sequence ID" value="XM_028671106.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRD1"/>
    <dbReference type="GeneID" id="39730903"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00237500"/>
    <dbReference type="OMA" id="ISMVMAR"/>
    <dbReference type="OrthoDB" id="421154at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000266">
        <property type="term" value="P:mitochondrial fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12212">
        <property type="entry name" value="Fis1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000347">
        <property type="entry name" value="Mitochondrial fission 1 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016543">
        <property type="entry name" value="Fis1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033745">
        <property type="entry name" value="Fis1_cytosol"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028061">
        <property type="entry name" value="Fis1_TPR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13247:SF0">
        <property type="entry name" value="MITOCHONDRIAL FISSION 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13247">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 11 TPR REPEAT PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14853">
        <property type="entry name" value="Fis1_TPR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF008835">
        <property type="entry name" value="TPR_repeat_11_Fis1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="1" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="66"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR008835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="141" mass="16137" checksum="389A76B3A88B7C32" modified="2017-02-15" version="1">MDSPEFLKIELQRLKSDYETELSIDHVMPKTQFDYACLLICSSDTKNIKFASSLLHELLLINYNRIDCLYQLAIAHIKLRDYKKAKNYLNALLKIDARNSNALALKSLLFDLISSDGLIGALLVALTMCGIYLSFKSFKYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRK5</accession>
    <name>A0A1J1GRK5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00162900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526741.1">
        <property type="nucleotide sequence ID" value="XM_028675184.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRK5"/>
    <dbReference type="GeneID" id="39730154"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00162900"/>
    <dbReference type="OMA" id="RYIWFIF"/>
    <dbReference type="OrthoDB" id="377522at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="195" mass="23166" checksum="A640B641402224AE" modified="2017-02-15" version="1">MCIRRIPGFHEKIHRSIFRRKNSGPSPLYKTPLRHIWAIFFYIDVFILYIYVLSFFFSIITRHECFEIFPIVFLTAVNLISSFFIDFFFLLIKDKEVVSEDEIILSTFFTILCCIIKIIVNVYIFYTSLNYFGKIFDSSDNDIKTRCHTSVTKGILLNFIVITAFPFVETYIESILTFFSIVHFKSQVQKYEMII</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRQ4</accession>
    <name>A0A1J1GRQ4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00235500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527771.1">
        <property type="nucleotide sequence ID" value="XM_028671082.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRQ4"/>
    <dbReference type="GeneID" id="39730883"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00235500"/>
    <dbReference type="OMA" id="MQFNGEN"/>
    <dbReference type="OrthoDB" id="363961at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013357567" evidence="1">
        <location>
            <begin position="21"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="403" mass="46975" checksum="33F308EAD7CE736A" modified="2017-02-15" version="1">MKSKSVLFFFLYLFTLFIDGIHISNKSYINEKNILIHENNTLKKNRGNIYKNNNRGNYLPNEKRGISRKRSNLLYLGNYPKLKRKKTNFNRNINILYAENYQINLTEKPVIDDVPRNVKGRLNEWINEFDENNTLGFFPILLEEMSNEPSPLQIGFEDYMQFNGENVEEIFKSMTREVSINGEKKKIFGMCFFNHKTGVLAPLAIYAEIKDVTKVGNNLAVKGLVRGRIIIDEIISQEPCILGKISPIEDKKGLIDGEESLKVIDEIIRIHSQCTTMESQLMEQLDQSFASMNIKLRNDLKESIDSKLEKFQIDPSDIEQRQAFIQIVSFAAFDFHLMIVDRYDALMLQNSEDRLRFVRDKIRQKQKQLAIIKNTPKEKLQEILEQVQNLKNQNLPPVNFPKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRZ0</accession>
    <name>A0A1J1GRZ0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WD repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00246700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527881.1">
        <property type="nucleotide sequence ID" value="XM_028671206.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRZ0"/>
    <dbReference type="GeneID" id="39730995"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00246700"/>
    <dbReference type="OMA" id="DMYRIKK"/>
    <dbReference type="OrthoDB" id="370170at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="330"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="385" mass="46323" checksum="ED2EE5D390B6EB63" modified="2017-02-15" version="1">MNIENKMMKSCFKWRNIFSFLKEKEKEKVLLHNCIQTLLSDPIVVLYTDDDYICTGSLTGKVCLYKITKKENKEVNTEISLIDNKKKIESDEQILNDMNKNEFKEINNNSNNEDVLRNKKEINNNEIIEKYHIICMFRNNSIKSIYIDKQYVYIYYENCIDVFSIKTYQFIKKVNLEVSNNKQVIYYENLILFNNSKNLFIYDITNNFMSYFYKNFLKNIVIFDFNINYLLCYKNNFGKCHIRVLQISTNSQKCDHELIFCVDFSSSKFISHGKFLDDEKIIVAKNGNRLIIFDFKKAIDMYRIKKLKKKILDIYKSVENMLFILVENQILIFNLSTFLFFKCVQLPVGLFYFKWSYFIRYKNNKIIFSCDKGIYFIDYQFEEND</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS15</accession>
    <name>A0A1J1GS15_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">U5 small nuclear ribonuclear protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00380000</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526917.1">
        <property type="nucleotide sequence ID" value="XM_028670135.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS15"/>
    <dbReference type="GeneID" id="39732330"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00380000"/>
    <dbReference type="OMA" id="YIFRPIR"/>
    <dbReference type="OrthoDB" id="364892at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071007">
        <property type="term" value="C:U2-type catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030623">
        <property type="term" value="F:U5 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04098">
        <property type="entry name" value="eEF2_C_snRNP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04090">
        <property type="entry name" value="EF2_II_snRNP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01683">
        <property type="entry name" value="EF2_IV_snRNP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16264">
        <property type="entry name" value="snRNP_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04167">
        <property type="entry name" value="Snu114p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.240:FF:000004">
        <property type="entry name" value="116 kDa U5 small nuclear ribonucleoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000029">
        <property type="entry name" value="116 kDa U5 small nuclear ribonucleoprotein component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000002">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1430.10">
        <property type="entry name" value="Yeast translation eEF2 (G' domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
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        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031950">
        <property type="entry name" value="EFTUD2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044121">
        <property type="entry name" value="Snu114_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035655">
        <property type="entry name" value="U5-116kDa_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF6">
        <property type="entry name" value="116 KDA U5 SMALL NUCLEAR RIBONUCLEOPROTEIN COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16004">
        <property type="entry name" value="EFTUD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="8">
        <location>
            <begin position="164"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="17"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1184" mass="137365" checksum="225CF0CAD49453E7" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSA9</accession>
    <name>A0A1J1GSA9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transporter, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00015400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528196.1">
        <property type="nucleotide sequence ID" value="XM_028671556.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSA9"/>
    <dbReference type="GeneID" id="39728676"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00015400"/>
    <dbReference type="OMA" id="CIKYIGT"/>
    <dbReference type="OrthoDB" id="6581954at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035725">
        <property type="term" value="P:sodium ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616:SF240">
        <property type="entry name" value="BLOATED TUBULES, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616">
        <property type="entry name" value="SODIUM/CHLORIDE DEPENDENT TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SNF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="278"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="307"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="346"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="476"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="500"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="541"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="588"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="649"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="688"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="712"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="751"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="779"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="847"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="896"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="979" mass="114746" checksum="9A0CF40FBDC90D88" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSH1</accession>
    <name>A0A1J1GSH1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter B family member 4, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ABCB4</name>
        <name evidence="10" type="ORF">PGAL8A_00001900</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528065.1">
        <property type="nucleotide sequence ID" value="XM_028671409.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSH1"/>
    <dbReference type="GeneID" id="39728541"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00001900"/>
    <dbReference type="OMA" id="QSCTIEQ"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF1">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012430210" evidence="7">
        <location>
            <begin position="19"/>
            <end position="1272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="282"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="314"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="159"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="937"/>
            <end position="1270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="568"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="802"/>
            <end position="835"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG95254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1272" mass="150782" checksum="9AF27E2C253BE6FF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSH9</accession>
    <name>A0A1J1GSH9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Palmitoyltransferase</fullName>
            <ecNumber evidence="8">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">DHHC1</name>
        <name evidence="10" type="ORF">PGAL8A_00002700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528073.1">
        <property type="nucleotide sequence ID" value="XM_028671418.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSH9"/>
    <dbReference type="GeneID" id="39728549"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00002700"/>
    <dbReference type="OMA" id="YYYVFLY"/>
    <dbReference type="OrthoDB" id="331948at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24161">
        <property type="entry name" value="ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24161:SF85">
        <property type="entry name" value="PALMITOYLTRANSFERASE HIP14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="474"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="506"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="7">
        <location>
            <begin position="157"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="7">
        <location>
            <begin position="190"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="9">
        <location>
            <begin position="426"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG95262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="609" mass="72971" checksum="AE387B3B50B6C1A1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSL2</accession>
    <name>A0A1J1GSL2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">KHDC4/BBP-like KH-domain type I domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00002100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528067.1">
        <property type="nucleotide sequence ID" value="XM_028671412.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSL2"/>
    <dbReference type="GeneID" id="39728543"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00002100"/>
    <dbReference type="OMA" id="NMIQQVR"/>
    <dbReference type="OrthoDB" id="377772at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055256">
        <property type="entry name" value="KH_1_KHDC4/BBP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22675">
        <property type="entry name" value="KH-I_KHDC4-BBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KHDC4/BBP-like KH-domain type I" evidence="1">
        <location>
            <begin position="253"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="443" mass="51439" checksum="F62815231902732C" modified="2017-02-15" version="1">MNNILLNQQMYPINSKDQNNLKLNNNISNRDTSYQRNNNIGKMSMNNITSNNIYNNSNNLNSNNYSLGLFIDNPQNAFIFDEKDLKTLFSHYKGAKSIRILNDKAAAQITFYDQNMIQQVKKDINGLTINDIGTIRCIILNEGKVIEQFLPFSANDPAHLQNSNLSSNNENTVNMLKKLATLLQPQNNTNIKKKNDMNQMTKNQLSNKTNYTNYINSNNNFNPVHNKNDQNENPYANKRLSRIELIDIFGFPSEFDVMKKILGKNNSNITYINEQTNNNVKIEIKGKPINEAPVVERMHISVSSDDIPSYKKGIELVIKLLNSIFKEFCDFCYEKKYPIPDNLAFKKHEYTYNPDGTTKYLGYKEKSHVLKENMKNDYMHKKNKNIQKGEKDKRVPNISYNMYSNSNPQYNNQNMLSGDFKEINYKESNQGNFRNIKLNRTRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSU9</accession>
    <name>A0A1J1GSU9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GTPase-activating protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00276900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528380.1">
        <property type="nucleotide sequence ID" value="XM_028671760.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSU9"/>
    <dbReference type="GeneID" id="39731302"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00276900"/>
    <dbReference type="OMA" id="IQEDKFW"/>
    <dbReference type="OrthoDB" id="18431at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050302">
        <property type="entry name" value="Rab_GAP_TBC_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219:SF9">
        <property type="entry name" value="GTPASE ACTIVATING PROTEIN AND CENTROSOME-ASSOCIATED, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47219">
        <property type="entry name" value="RAB GTPASE-ACTIVATING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="661"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="733"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="758"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="domain" description="Rab-GAP TBC" evidence="4">
        <location>
            <begin position="419"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="516"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="202"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="524"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="536"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="567"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="841" mass="101629" checksum="C08C095CA14B28E3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSV3</accession>
    <name>A0A1J1GSV3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00383500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526952.1">
        <property type="nucleotide sequence ID" value="XM_028670173.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSV3"/>
    <dbReference type="GeneID" id="39732365"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00383500"/>
    <dbReference type="OMA" id="HIYEQEY"/>
    <dbReference type="OrthoDB" id="372726at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="99"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="207" mass="24398" checksum="1AEB87534E06A6C8" modified="2017-02-15" version="1">MNFVKTHIYKQIYTNEGIQELEKDTRSKKELVENQILKGLPEFKRDNQFLSLSEQLELKKNTATLEDNDNNTNLYGLPSLTEEDLEYYENYEKNDNYSIEKLKERERELVNEFNEAIKGYIKKKRKKETDLDILKENVNLSEIKKSINKKKAVEFKPTVKAIIKTKKNKNTINSENKKINLKVSCENKKIETEENSLLFGYSDNSDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT49</accession>
    <name>A0A1J1GT49_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Calmodulin, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00289900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528510.1">
        <property type="nucleotide sequence ID" value="XM_028671904.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT49"/>
    <dbReference type="GeneID" id="39731432"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00289900"/>
    <dbReference type="OMA" id="SFIIMDK"/>
    <dbReference type="OrthoDB" id="429467at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13405">
        <property type="entry name" value="EF-hand_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="1">
        <location>
            <begin position="3"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="138" mass="16039" checksum="91A6E4037902AABD" modified="2017-02-15" version="1">MSKTDAIIRESFLLIDKDFDGSISLNELMYALRFIGVPFDYSMIEEKNNMKYSLGEYVQIAKKHLGTLTPEEQFINTIKKFDKKNDGTLAIDTTIHLVMTMSDILCDEDLINFKKFIDPYDKKMIPMEEFANKVFSQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT84</accession>
    <name>A0A1J1GT84_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ERCC1 nucleotide excision repair protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00021000</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ERCC1/RAD10/SWI10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528251.1">
        <property type="nucleotide sequence ID" value="XM_028671616.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT84"/>
    <dbReference type="GeneID" id="39728732"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00021000"/>
    <dbReference type="OMA" id="PHCVLVH"/>
    <dbReference type="OrthoDB" id="10262814at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070522">
        <property type="term" value="C:ERCC4-ERCC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000110">
        <property type="term" value="C:nucleotide-excision repair factor 1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006312">
        <property type="term" value="P:mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070914">
        <property type="term" value="P:UV-damage excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22325">
        <property type="entry name" value="ERCC1_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10130:FF:000001">
        <property type="entry name" value="DNA excision repair protein ERCC-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047260">
        <property type="entry name" value="ERCC1-like_central_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004579">
        <property type="entry name" value="ERCC1/RAD10/SWI10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00597">
        <property type="entry name" value="rad10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12749:SF0">
        <property type="entry name" value="DNA EXCISION REPAIR PROTEIN ERCC-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12749">
        <property type="entry name" value="EXCISION REPAIR CROSS-COMPLEMENTING 1 ERCC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03834">
        <property type="entry name" value="Rad10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="Restriction endonuclease-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="RuvA domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERCC1-like central" evidence="8">
        <location>
            <begin position="34"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG95440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="226" mass="26480" checksum="C11589F7F58273E0" modified="2017-02-15" version="1">MSEDISKLKSVEDKPSDTHETNEVFYDDDSENFLIISHRQKLNPLIKKINRVRYKFNNIIPDFLIGKNNACLFISMKYHRLRSNYLKARIETLSNKYNNRILLCLVDIDNIDNSLGEINQLAFCLNMTLILCWSNEECARVIEDFKIYEKKISYLKNKVSSKQDEKIFELLKKIRCINSTDCVTLIKKFKNFKNIIKAKKDELINCSGLGNKKINALISTFNDPFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT93</accession>
    <name>A0A1J1GT93_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Copper transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00293700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528540.1">
        <property type="nucleotide sequence ID" value="XM_028671937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT93"/>
    <dbReference type="GeneID" id="39731470"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00293700"/>
    <dbReference type="OrthoDB" id="161814at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005375">
        <property type="term" value="F:copper ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007274">
        <property type="entry name" value="Cop_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483:SF27">
        <property type="entry name" value="COPPER TRANSPORT PROTEIN CTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12483">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04145">
        <property type="entry name" value="Ctr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0186">Copper</keyword>
    <keyword evidence="5" id="KW-0187">Copper transport</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="158" mass="18696" checksum="F17C23F4AA8356CD" modified="2017-02-15" version="1">MVGKYSKYSLCTIVIIYILSNFQFVSSSCHSEYNKDGLLLPMYFSNNINIKFLFDYFQVKNVYQFVFLNILCILMGFSSIYIKMIKKGFDKKNSEDVEEKHFLLKIFRNKDFIYGLLSFLNYAIDYLLMLIVMTFNPYIFLSIMIGLSSAYFFYGHLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTL0</accession>
    <name>A0A1J1GTL0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00276800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528379.1">
        <property type="nucleotide sequence ID" value="XM_028671759.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTL0"/>
    <dbReference type="GeneID" id="39731301"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00276800"/>
    <dbReference type="OMA" id="NILCHVI"/>
    <dbReference type="OrthoDB" id="371139at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="689" mass="84041" checksum="22E6CB5970772B70" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUA5</accession>
    <name>A0A1J1GUA5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mediator of RNA polymerase II transcription subunit 6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Mediator complex subunit 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MED6</name>
        <name evidence="7" type="ORF">PGAL8A_00229200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the Mediator complex subunit 6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUA5"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00229200"/>
    <dbReference type="OMA" id="IHIYYNT"/>
    <dbReference type="OrthoDB" id="344220at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.580">
        <property type="entry name" value="Mediator complex, subunit Med6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007018">
        <property type="entry name" value="Mediator_Med6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038566">
        <property type="entry name" value="Mediator_Med6_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04934">
        <property type="entry name" value="Med6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0010">Activator</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 6" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG94895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="203" mass="24019" checksum="A475963584581B53" modified="2017-02-15" version="1">MEEPYYESVLKKENKIEYVDNLYLSKNILNNKENALNYFYTSPFYTSRSHLSLNEKIRSGKNISDDEEGYIFGVTYDNLSILKSNEPNDLVNIHIYYNTNSIFHISLTHRFKLKNIICSKTVQMFCIFNGKIYSSRSFGELLTNKINNIVRNVENFFDCVNNMMNFNITSNYYFESKIDEEIDDIYKNYQLEDVFVSTKKTNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUB0</accession>
    <name>A0A1J1GUB0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00326100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000053">
        <property type="protein sequence ID" value="CRG96047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528855.1">
        <property type="nucleotide sequence ID" value="XM_028672287.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUB0"/>
    <dbReference type="GeneID" id="39731793"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00326100"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009618946" evidence="2">
        <location>
            <begin position="23"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="254" mass="30471" checksum="7C86E9529276B782" modified="2017-02-15" version="1">MKTLTLYLKITTFFLLIWMYQCFYNCDCNKCLIDKNILQAKNKLKYERVLTEGDIPGKKQTNTEGCLEECPLDDKKNKCKNPDQCENPCDRWQRVNTPLLWERFYGETSGIDPKLKKKKWNVEWNEISANNVNHLSSIIYRRDIPDEEKGKLILSVMKEQLKLKKLLDEYEKEMRDNKTESESKNEMRDNKTESESKKEMRDNKKESESMNEMRESKAESESKKKQGKNKKKNKKLNIWKFLFNRFDNLYENKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUC7</accession>
    <name>A0A1J1GUC7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nucleic acid binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00334400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528934.1">
        <property type="nucleotide sequence ID" value="XM_028672375.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUC7"/>
    <dbReference type="GeneID" id="39731874"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00334400"/>
    <dbReference type="OMA" id="DIYMPND"/>
    <dbReference type="OrthoDB" id="21467at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050441">
        <property type="entry name" value="RBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48034">
        <property type="entry name" value="TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="333"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="617"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="158"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="158"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="189"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="202"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="707" mass="82628" checksum="5790127214795CD3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUJ6</accession>
    <name>A0A1J1GUJ6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Zinc finger transcription factor, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">KROX1</name>
        <name evidence="14" type="ORF">PGAL8A_00312800</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the krueppel C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528723.1">
        <property type="nucleotide sequence ID" value="XM_028672140.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731661"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00312800"/>
    <dbReference type="OMA" id="TCPYENC"/>
    <dbReference type="OrthoDB" id="372803at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000145">
        <property type="entry name" value="Zinc finger protein 574"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050636">
        <property type="entry name" value="C2H2-ZF_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47772:SF15">
        <property type="entry name" value="REDUCED EXPRESSION 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47772">
        <property type="entry name" value="ZINC FINGER PROTEIN 200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12874">
        <property type="entry name" value="zf-met"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="876"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="905"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="1184"/>
            <end position="1212"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="1213"/>
            <end position="1240"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="1244"/>
            <end position="1266"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="1324"/>
            <end position="1352"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="1354"/>
            <end position="1384"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="13">
        <location>
            <begin position="1385"/>
            <end position="1409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="276"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="439"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="688"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1008"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="538"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="465"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="479"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="719"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="797"/>
            <end position="808"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG95915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1409" mass="166563" checksum="6DD06C7374642D09" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUK3</accession>
    <name>A0A1J1GUK3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dynein light chain type 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00340900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528996.1">
        <property type="nucleotide sequence ID" value="XM_028672445.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUK3"/>
    <dbReference type="GeneID" id="39731939"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00340900"/>
    <dbReference type="OMA" id="FQFFANT"/>
    <dbReference type="OrthoDB" id="10248487at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21459">
        <property type="entry name" value="DLC-like_TCTEX1D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.40">
        <property type="entry name" value="Tctex-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005334">
        <property type="entry name" value="Tctex-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038586">
        <property type="entry name" value="Tctex-1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21255:SF7">
        <property type="entry name" value="DYNEIN LIGHT CHAIN TCTEX-TYPE PROTEIN 2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21255">
        <property type="entry name" value="T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03645">
        <property type="entry name" value="Tctex-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="89"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="182" mass="21126" checksum="4E3CABD0DC284676" modified="2017-02-15" version="1">MEIGNKNNATNVEANGIEKNNDENSKVDMEGFRFFANICEEKLKIFLENFFSSKNQDELFYLEDKIITTKTDINDENHDSSNENHDSSNENQNNYSEKNNIIKSNYDKMVISLVDDVEQFMKSFVNERYKIIVQGVIGENKKQGIHIASKSLWNVETDNYISANYVNDSIFVTVMVFLLYNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUM7</accession>
    <name>A0A1J1GUM7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Shewanella-like protein phosphatase 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SHLP2</name>
        <name evidence="3" type="ORF">PGAL8A_00316000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528755.1">
        <property type="nucleotide sequence ID" value="XM_028672175.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUM7"/>
    <dbReference type="GeneID" id="39731693"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00316000"/>
    <dbReference type="OMA" id="GPTLNRY"/>
    <dbReference type="OrthoDB" id="5976022at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46546">
        <property type="entry name" value="SHEWANELLA-LIKE PROTEIN PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46546:SF4">
        <property type="entry name" value="SHEWANELLA-LIKE PROTEIN PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012181806" evidence="1">
        <location>
            <begin position="19"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="2">
        <location>
            <begin position="32"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="294" mass="34417" checksum="6BC037C97CC10056" modified="2017-02-15" version="1">MFIYFLIVLFDTFYICDMNFSNFKWTHDLFSISDLHGDMDSFIKILLNEQIIDKDNNILKENVLIVITGDILDPNYDDINIVFFIEGFNEKGKDKNSSILLILGNHEVKNLCLDFNKKKKDSNKYNSRNKLFKKNEKIYNYLIKNPFVVKVNDIIFSHAGVLPFYSSYGINFINEEGKKEIENNCELLKEKKKKKEELCICCEYGPTLNRYYSYISNNIFKKSKVCSTLIKSLKLLKSNKMVIGHTVQKNKKVNSFCEGKLLLADTAISKWKKGVISYVQYFKNGTYNVKYIER</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUS8</accession>
    <name>A0A1J1GUS8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">glutaminase</fullName>
            <ecNumber evidence="2">3.5.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00342800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-glutamine + H2O = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutaminase PdxT/SNO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.2" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529015.1">
        <property type="nucleotide sequence ID" value="XM_028672465.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUS8"/>
    <dbReference type="GeneID" id="39731958"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00342800"/>
    <dbReference type="OMA" id="GMIMLAD"/>
    <dbReference type="OrthoDB" id="2039at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903600">
        <property type="term" value="C:glutaminase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042823">
        <property type="term" value="P:pyridoxal phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008614">
        <property type="term" value="P:pyridoxine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01749">
        <property type="entry name" value="GATase1_PB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002161">
        <property type="entry name" value="PdxT/SNO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021196">
        <property type="entry name" value="PdxT/SNO_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03800">
        <property type="entry name" value="PLP_synth_Pdx2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31559">
        <property type="entry name" value="PYRIDOXAL 5'-PHOSPHATE SYNTHASE SUBUNIT SNO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31559:SF0">
        <property type="entry name" value="PYRIDOXAL 5'-PHOSPHATE SYNTHASE SUBUNIT SNO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01174">
        <property type="entry name" value="SNO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005639">
        <property type="entry name" value="Glut_amidoT_SNO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01236">
        <property type="entry name" value="PDXT_SNO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51130">
        <property type="entry name" value="PDXT_SNO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="52"/>
            <end position="54"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="153"/>
            <end position="154"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR005639-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR005639-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG96210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="219" mass="24813" checksum="37E2BF22AC553AB9" modified="2017-02-15" version="1">MSSVTIGVLSLQGDFQPHINHFLKLEEPSLQIKEVRDKKDLSECDGLVIPGGESTTLRKCFAYDNDSLFNAIKNFIHVEQNPVWGTCAGCILLSKKVENIEMHSEYGKNFSLGGLDIVICRNFYGSQNDSFICSLNINSYNNIFNKNLRAACIRSPYIKEVLSDDVEILATFTHEITGSNIIAAVEQNNCIGTVFHPELMPYSSFHRYFYEKVKNYKYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUX0</accession>
    <name>A0A1J1GUX0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Adenine DNA glycosylase</fullName>
            <ecNumber evidence="4">3.2.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PGAL8A_00356300</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolyzes free adenine bases from 7,8-dihydro-8-oxoguanine:adenine mismatched double-stranded DNA, leaving an apurinic site.</text>
            <dbReference type="EC" id="3.2.2.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Nth/MutY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.31" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529150.1">
        <property type="nucleotide sequence ID" value="XM_028672615.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUX0"/>
    <dbReference type="GeneID" id="39732093"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00356300"/>
    <dbReference type="OMA" id="YLKWMNK"/>
    <dbReference type="OrthoDB" id="10248838at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034039">
        <property type="term" value="F:8-oxo-7,8-dihydroguanine DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035485">
        <property type="term" value="F:adenine/guanine mispair binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032357">
        <property type="term" value="F:oxidized purine DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000701">
        <property type="term" value="F:purine-specific mismatch base pair DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="entry name" value="Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044298">
        <property type="entry name" value="MIG/MutY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42944">
        <property type="entry name" value="ADENINE DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42944:SF1">
        <property type="entry name" value="ADENINE DNA GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH-GPD" evidence="13">
        <location>
            <begin position="197"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG96345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="577" mass="68948" checksum="20C23933A91566C9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVA2</accession>
    <name>A0A1J1GVA2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tetratricopeptide repeat family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00343800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529025.1">
        <property type="nucleotide sequence ID" value="XM_028672476.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731968"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00343800"/>
    <dbReference type="OrthoDB" id="377203at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="146"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1491" mass="180661" checksum="677150C056B76759" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVA6</accession>
    <name>A0A1J1GVA6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">L-lactate dehydrogenase</fullName>
            <ecNumber evidence="4">1.1.1.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">LDH</name>
        <name evidence="15" type="ORF">PGAL8A_00236800</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(S)-lactate + NAD(+) = pyruvate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23444"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16651"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Fermentation; pyruvate fermentation to lactate; (S)-lactate from pyruvate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LDH/MDH superfamily. LDH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.27" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527784.1">
        <property type="nucleotide sequence ID" value="XM_028671098.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVA6"/>
    <dbReference type="GeneID" id="39730896"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00236800"/>
    <dbReference type="OMA" id="EWDLDDY"/>
    <dbReference type="OrthoDB" id="5405561at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004459">
        <property type="term" value="F:L-lactate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006089">
        <property type="term" value="P:lactate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01339">
        <property type="entry name" value="LDH-like_MDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000362">
        <property type="entry name" value="L-lactate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="entry name" value="Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011275">
        <property type="entry name" value="Malate_DH_type3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004863">
        <property type="entry name" value="PRK06223.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43128">
        <property type="entry name" value="L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+))"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43128:SF16">
        <property type="entry name" value="L-LACTATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00086">
        <property type="entry name" value="LLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="LDH C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0520">NAD</keyword>
    <keyword evidence="6 12 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactate/malate dehydrogenase N-terminal" evidence="13">
        <location>
            <begin position="6"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Lactate/malate dehydrogenase C-terminal" evidence="14">
        <location>
            <begin position="154"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="11"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="125"/>
            <end position="127"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG94971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="316" mass="34427" checksum="306B8587985823CE" modified="2017-02-15" version="1">MAPKPKFVLVGSGMIGGVMATLIVQKNLGDVVLFDIVKNMPQGKALDTSHTNVMAYSNCKVTGSNSYDDLKGADVVIVTAGFTKAPGKSDKEWNRDDLLPLNNKIMIEIGGHIKKNCPNAFIIVVTNPVDVMVQLLYQHSGVPKNKIIGLGGVLDTSRLKYYISQKLNVCPRDVNALIVGAHGNKMVPLLRYITVGGVPLQEFIDNKKISKEEIDTIFDRTINTALEIVNLYASPFVAPAAAIIEMAESYVRDLKKVLVCSTLLEGQYGHTDIFGGTPIVLGANGVEQVIELQLTKDEKKKFDEAIAETRRMKALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVK0</accession>
    <name>A0A1J1GVK0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPS21</name>
        <name evidence="5" type="ORF">PGAL8A_00371500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529295.1">
        <property type="nucleotide sequence ID" value="XM_028672776.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVK0"/>
    <dbReference type="GeneID" id="39732245"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00371500"/>
    <dbReference type="OMA" id="GESDACM"/>
    <dbReference type="OrthoDB" id="278325at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022626">
        <property type="term" value="C:cytosolic ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1230.20:FF:000001">
        <property type="entry name" value="40S ribosomal protein S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1230.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001931">
        <property type="entry name" value="Ribosomal_eS21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038579">
        <property type="entry name" value="Ribosomal_eS21_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10442">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01249">
        <property type="entry name" value="Ribosomal_S21e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002148">
        <property type="entry name" value="Ribosomal_S21e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR002148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="82" mass="9122" checksum="1280C0242364B88B" modified="2017-02-15" version="1">MFNDQKVLVDIYIPRKCSATSRLIPAKEHGAVQINVGMVDENGVYNGKSETFAISGHVRQKGESDACLNRLLHEKNMLSFSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVR5</accession>
    <name>A0A1J1GVR5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">50S ribosomal protein L33, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00014700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528189.1">
        <property type="nucleotide sequence ID" value="XM_028671548.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVR5"/>
    <dbReference type="GeneID" id="39728669"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00014700"/>
    <dbReference type="OMA" id="MHGINYA"/>
    <dbReference type="OrthoDB" id="275534at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.120">
        <property type="entry name" value="Ribosomal protein L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001705">
        <property type="entry name" value="Ribosomal_bL33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038584">
        <property type="entry name" value="Ribosomal_bL33_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01023">
        <property type="entry name" value="rpmG_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00471">
        <property type="entry name" value="Ribosomal_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="119" mass="14150" checksum="20F9EE6DA476B3CB" modified="2017-02-15" version="1">MLFLSNVFFRSKSKRVHINLISSCASNYIYSTYISPNKSKFRLSLRKHDPVVNRHVMFYQKHMKSKSKKKLSLHGINYARFTGKNKNLRPLLKRVEKAYLYGKFNKLVDNTYRSLPRMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVU3</accession>
    <name>A0A1J1GVU3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA-directed RNA polymerase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00017900</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528221.1">
        <property type="nucleotide sequence ID" value="XM_028671583.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVU3"/>
    <dbReference type="GeneID" id="39728701"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00017900"/>
    <dbReference type="OMA" id="MEFCDEC"/>
    <dbReference type="OrthoDB" id="282152at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006386">
        <property type="term" value="P:termination of RNA polymerase III transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10509">
        <property type="entry name" value="Zn-ribbon_RPC11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.10:FF:000031">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012164">
        <property type="entry name" value="Rpa12/Rpb9/Rpc10/TFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034014">
        <property type="entry name" value="Zn_ribbon_RPC11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001222">
        <property type="entry name" value="Znf_TFIIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239:SF12">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01096">
        <property type="entry name" value="Zn_ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005586">
        <property type="entry name" value="RNApol_RpoM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00440">
        <property type="entry name" value="ZnF_C2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00466">
        <property type="entry name" value="ZF_TFIIS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51133">
        <property type="entry name" value="ZF_TFIIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 9 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIS-type" evidence="11">
        <location>
            <begin position="65"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="9">
        <location>
            <begin position="5"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="5"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR005586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR005586-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR005586-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG95410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="106" mass="12592" checksum="6417FFF5BB93E50C" modified="2017-02-15" version="1">MAFFCPNCHNIVLVHIENGVYFYCKSCNYRYKIKNKIYNKFDCQKYNKTISLDAVDMSNKNMSKTQAVCPKCTNDEAYFYSLQIRSADEPSTIFYICVKCNYHWKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVV5</accession>
    <name>A0A1J1GVV5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Elongation factor 1-beta, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00426000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EF-1-beta/EF-1-delta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529484.1">
        <property type="nucleotide sequence ID" value="XM_028672986.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVV5"/>
    <dbReference type="GeneID" id="39732792"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00426000"/>
    <dbReference type="OMA" id="YRWYKHI"/>
    <dbReference type="OrthoDB" id="331763at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005853">
        <property type="term" value="C:eukaryotic translation elongation factor 1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00292">
        <property type="entry name" value="EF1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.60:FF:000004">
        <property type="entry name" value="Elongation factor 1-beta, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036219">
        <property type="entry name" value="eEF-1beta-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049720">
        <property type="entry name" value="EF1B_bsu/dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014038">
        <property type="entry name" value="EF1B_bsu/dsu_GNE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribsomal_bS6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11595">
        <property type="entry name" value="EF-HAND AND COILED-COIL DOMAIN-CONTAINING FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11595:SF21">
        <property type="entry name" value="ELONGATION FACTOR 1-BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00736">
        <property type="entry name" value="EF1_GNE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00888">
        <property type="entry name" value="EF1_GNE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54984">
        <property type="entry name" value="eEF-1beta-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 6" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Translation elongation factor EF1B beta/delta subunit guanine nucleotide exchange" evidence="5">
        <location>
            <begin position="143"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="117"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="270" mass="31813" checksum="F690247EF0CDC2E5" modified="2017-02-15" version="1">MANNANLLNVQGENDYNKLNAFFADHSYYQNYMLSTSDIKIYNQITTTINKDKYPHLYRWYKHISSLPTHIFNQYNKCNEKVKKNNLPEKKINETKNDDDDVDNDIDLFGDNDDCDKDILLEKKKQKEEELKKKQQKEKDKHRSILIIEIKPKSIDTDISKISKLVKQKIVDENIKWGEEVKKIPVAFGLYKLQMSCIIYDDFVNTNDLIEKIENIDLDNEEDRKKRTLILGLDEENEDADEMSETEDIEVEDDLDFLVQSAEIVSFNKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVW2</accession>
    <name>A0A1J1GVW2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00256000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527968.1">
        <property type="nucleotide sequence ID" value="XM_028671302.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731088"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00256000"/>
    <dbReference type="OMA" id="MYSNSPI"/>
    <dbReference type="OrthoDB" id="372210at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="601"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="913"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1050"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1136"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="601"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="731"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="747"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="757"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1050"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1142"/>
            <end position="1161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1523" mass="179167" checksum="B61C9ADEEF6F5466" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVX2</accession>
    <name>A0A1J1GVX2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">mitogen-activated protein kinase kinase</fullName>
            <ecNumber evidence="6">2.7.12.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00021200</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10596"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.12.2" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528253.1">
        <property type="nucleotide sequence ID" value="XM_028671618.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728734"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00021200"/>
    <dbReference type="OMA" id="NIDVNEW"/>
    <dbReference type="OrthoDB" id="10252354at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004708">
        <property type="term" value="F:MAP kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48013:SF9">
        <property type="entry name" value="DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48013">
        <property type="entry name" value="DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="1798"/>
            <end position="2084"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="675"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="809"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1720"/>
            <end position="1801"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="31"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="2169"/>
            <end position="2196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1728"/>
            <end position="1791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1792"/>
            <end position="1801"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00051693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG95442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2214" mass="263587" checksum="1FC88A713A5D5741" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVY5</accession>
    <name>A0A1J1GVY5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ubiquitin fusion degradation protein 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">UFD1</name>
        <name evidence="6" type="ORF">PGAL8A_00429400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UFD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529518.1">
        <property type="nucleotide sequence ID" value="XM_028673024.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVY5"/>
    <dbReference type="GeneID" id="39732826"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00429400"/>
    <dbReference type="OrthoDB" id="422728at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034098">
        <property type="term" value="C:VCP-NPL4-UFD1 AAA ATPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.50">
        <property type="entry name" value="Ubiquitin fusion degradation protein UFD1, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004854">
        <property type="entry name" value="Ufd1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042299">
        <property type="entry name" value="Ufd1-like_Nn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055417">
        <property type="entry name" value="UFD1_N1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055418">
        <property type="entry name" value="UFD1_N2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12555">
        <property type="entry name" value="UBIQUITIN FUSION DEGRADATON PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12555:SF13">
        <property type="entry name" value="UBIQUITIN RECOGNITION FACTOR IN ER-ASSOCIATED DEGRADATION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03152">
        <property type="entry name" value="UFD1_N1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24842">
        <property type="entry name" value="UFD1_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012498290" evidence="3">
        <location>
            <begin position="18"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin fusion degradation protein UFD1 N-terminal subdomain 1" evidence="4">
        <location>
            <begin position="88"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin fusion degradation protein UFD1 N-terminal subdomain 2" evidence="5">
        <location>
            <begin position="206"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF24842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="287" mass="34068" checksum="AE9232974A6D63A0" modified="2017-02-15" version="1">MVKIILSILLIFSFTLNISIYSKYTTKNNLSYFLTNKNNNKKNPYSNILTKIKNYTIKAIYKTELLTYLNDINNLNLGNGKNEFYLIALPLSTFCHNNIQYSDKASLPIFIYDILLNKHIEVPWNFVIEKVNIKKPLTYENVFMTDINKFCEHKNINKLDRIFINVLDFKSKKNFIFLPTWIMKTLNLNCFDVVRLRFVKLETCISVVLQPHDKKFFELEEPKKILEEKLRYYSCLTKNSTICINHDNFIYYFDVVRIDSENKKNVEVASIQDTDVIFDFVKEKYAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWI5</accession>
    <name>A0A1J1GWI5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Translation initiation factor SUI1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00420300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529427.1">
        <property type="nucleotide sequence ID" value="XM_028672923.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWI5"/>
    <dbReference type="GeneID" id="39732735"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00420300"/>
    <dbReference type="OMA" id="MIPGICK"/>
    <dbReference type="OrthoDB" id="199771at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001731">
        <property type="term" value="P:formation of translation preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11608">
        <property type="entry name" value="eIF2D_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21156">
        <property type="entry name" value="PUA_eIF2d-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.780.10:FF:000012">
        <property type="entry name" value="Translation initiation factor SUI1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.400.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.780.10">
        <property type="entry name" value="SUI1-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039757">
        <property type="entry name" value="EIF2D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039759">
        <property type="entry name" value="eIF2D_SUI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041366">
        <property type="entry name" value="Pre-PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048248">
        <property type="entry name" value="PUA_eIF2d-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001950">
        <property type="entry name" value="SUI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036877">
        <property type="entry name" value="SUI1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058886">
        <property type="entry name" value="SWIB_eIF2D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036885">
        <property type="entry name" value="SWIB_MDM2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057429">
        <property type="entry name" value="WH_eIF2D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12217">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12217:SF4">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17832">
        <property type="entry name" value="Pre-PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26292">
        <property type="entry name" value="PUA_elF2D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01253">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26291">
        <property type="entry name" value="SWIB_eIF2D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25304">
        <property type="entry name" value="WHD_eIF2D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55159">
        <property type="entry name" value="eIF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47592">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50296">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SUI1" evidence="2">
        <location>
            <begin position="725"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="368"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="809" mass="95460" checksum="B88280510E22D28C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="42" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWI7</accession>
    <name>A0A1J1GWI7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 4">Histone deacetylase</fullName>
            <ecNumber evidence="1 4">3.5.1.98</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">HDAC1</name>
        <name evidence="10" type="ORF">PGAL8A_00438500</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>N(6)-acetyl-L-lysyl-[histone] + H2O = L-lysyl-[histone] + acetate</text>
            <dbReference type="Rhea" id="RHEA:58196"/>
            <dbReference type="Rhea" id="RHEA-COMP:9845"/>
            <dbReference type="Rhea" id="RHEA-COMP:11338"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="3.5.1.98"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the histone deacetylase family. HD Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.98" evidence="1 4"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529607.1">
        <property type="nucleotide sequence ID" value="XM_028673123.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWI7"/>
    <dbReference type="GeneID" id="39732918"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00438500"/>
    <dbReference type="OMA" id="NIPLMMV"/>
    <dbReference type="OrthoDB" id="1918432at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141221">
        <property type="term" value="F:histone deacetylase activity, hydrolytic mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040029">
        <property type="term" value="P:epigenetic regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09991">
        <property type="entry name" value="HDAC_classI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.800.20:FF:000010">
        <property type="entry name" value="Histone deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003084">
        <property type="entry name" value="HDAC_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF44">
        <property type="entry name" value="HISTONE DEACETYLASE 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037913">
        <property type="entry name" value="His_deacetylse_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01271">
        <property type="entry name" value="HISDACETLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="2 4 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="9">
        <location>
            <begin position="24"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="390"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="390"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR037913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR037913-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR037913-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR037913-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG96804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="448" mass="51422" checksum="E8B0B7341452D40C" modified="2017-02-15" version="1">MSNRKKVAYFHDPDIGSYYYGAGHPMKPQRIRMTHSLIVSYNLYKYMEVYRPHKSDVHEMTLFHDYEYVDFLSSITLENYREFTYQLKRFNVGEATDCPVFDGLFQFQQSCAGASIDGASKLNHHCADICINWSGGLHHAKMSEASGFCYINDIVLGILELLKYHARVMYIDIDVHHGDGVEEAFYVTHRVMTVSFHKFGDYFPGTGDITDIGVHHGKYYSVNVPLNDGITDEAFVDLFKVVIDKCVQTYKPGAIIIQCGADSLTGDRLGRFNLTIKGHAKCVEHVRSYNLPLLVLGGGGYTIRNVARCWTYETGVVLNKHHEMPDQISLNDYYDYYAPDFQLHLQPSNMPNYNSPEHLNRIKMKITENLRNIEHAPGVQFSYVPPDFFDSEMDDESDKNQYELDDDSGGGRAAGTRIKEHSSSHHLRRKNYEDDFFDLSDRDQKMIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWN9</accession>
    <name>A0A1J1GWN9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="11">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">RECQ1</name>
        <name evidence="15" type="ORF">PGAL8A_00431400</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="11"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529537.1">
        <property type="nucleotide sequence ID" value="XM_028673045.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWN9"/>
    <dbReference type="GeneID" id="39732846"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00431400"/>
    <dbReference type="OMA" id="CISTWGC"/>
    <dbReference type="OrthoDB" id="10261556at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17920">
        <property type="entry name" value="DEXHc_RecQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18794">
        <property type="entry name" value="SF2_C_RecQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004589">
        <property type="entry name" value="DNA_helicase_ATP-dep_RecQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032284">
        <property type="entry name" value="RecQ_Zn-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00614">
        <property type="entry name" value="recQ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710">
        <property type="entry name" value="DNA HELICASE RECQ FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710:SF153">
        <property type="entry name" value="RECQ-LIKE DNA HELICASE BLM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16124">
        <property type="entry name" value="RecQ_Zn_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 11 15" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="57"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="271"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="560"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU364117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG96733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="617" mass="72099" checksum="514F1E323AF95087" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWQ3</accession>
    <name>A0A1J1GWQ3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">XRRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00021500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528256.1">
        <property type="nucleotide sequence ID" value="XM_028671622.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWQ3"/>
    <dbReference type="GeneID" id="39728737"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00021500"/>
    <dbReference type="OMA" id="MVDVCLM"/>
    <dbReference type="OrthoDB" id="375014at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014886">
        <property type="entry name" value="La_xRRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08777">
        <property type="entry name" value="RRM_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="XRRM" evidence="3">
        <location>
            <begin position="15"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="71"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="120" mass="14681" checksum="268A165ED1CFFF73" modified="2017-02-15" version="1">MENKISCIYPNKPTGCIIRIKNIKCFENEIEIKHFFEHLVDICLIHSDYVKNEAYALMHSKQEALHFMKFYQQIFKNMKFLELENQNIEIEILNKEEEKIFWSNIRMKKIDFYICCKKHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWS1</accession>
    <name>A0A1J1GWS1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">P25-alpha family protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00458300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TPPP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529806.1">
        <property type="nucleotide sequence ID" value="XM_028673345.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWS1"/>
    <dbReference type="GeneID" id="39733116"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00458300"/>
    <dbReference type="OMA" id="NAFYIYT"/>
    <dbReference type="OrthoDB" id="548799at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001578">
        <property type="term" value="P:microtubule bundle formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046785">
        <property type="term" value="P:microtubule polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032273">
        <property type="term" value="P:positive regulation of protein polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008907">
        <property type="entry name" value="TPP/p25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12932">
        <property type="entry name" value="P25 ALPHA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12932:SF9">
        <property type="entry name" value="TUBULIN POLYMERIZATION-PROMOTING PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05517">
        <property type="entry name" value="p25-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="152" mass="17257" checksum="5CF9053E5C25CEB6" modified="2017-02-15" version="1">MENAFYIYTKNASDMDSRTFVKILKDSNLLNKKLTTVDADLTFARVKTKGAKRINYNQFVEAIRSLVDKHSLDYDKFVEQLCSEASNGPILYGTKTDHVRFFDDKSTYTGVHKQGGPTIVDKNRTKFSDLSEIVDRSEFNTRGVNVSVAKNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWU8</accession>
    <name>A0A1J1GWU8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00461500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529838.1">
        <property type="nucleotide sequence ID" value="XM_028673380.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733148"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00461500"/>
    <dbReference type="OMA" id="GKDHKSP"/>
    <dbReference type="OrthoDB" id="377534at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="47"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="486"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="705"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1047"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1208"/>
            <end position="1242"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1336"/>
            <end position="1582"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1607"/>
            <end position="1707"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1761"/>
            <end position="1837"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2000"/>
            <end position="2041"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2104"/>
            <end position="2198"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2248"/>
            <end position="2296"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2326"/>
            <end position="2409"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2493"/>
            <end position="2520"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2562"/>
            <end position="2596"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2738"/>
            <end position="2903"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2930"/>
            <end position="2985"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3069"/>
            <end position="3138"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3162"/>
            <end position="3256"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3285"/>
            <end position="3319"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3399"/>
            <end position="3507"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3544"/>
            <end position="3687"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3770"/>
            <end position="3990"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="4073"/>
            <end position="4100"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="4281"/>
            <end position="4500"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="4526"/>
            <end position="4602"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="4821"/>
            <end position="5037"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="5088"/>
            <end position="5115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="5246" mass="630510" checksum="B6CC61B0EEA00B5D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWX3</accession>
    <name>A0A1J1GWX3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Serine/threonine-protein phosphatase 2A activator</fullName>
            <ecNumber evidence="7">5.2.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Phosphotyrosyl phosphatase activator</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">PTPA</name>
        <name evidence="8" type="ORF">PGAL8A_00301700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the PTPA-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528613.1">
        <property type="nucleotide sequence ID" value="XM_028672018.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWX3"/>
    <dbReference type="GeneID" id="39731550"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00301700"/>
    <dbReference type="OMA" id="IHESQDV"/>
    <dbReference type="OrthoDB" id="16120at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008160">
        <property type="term" value="F:protein tyrosine phosphatase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04087">
        <property type="entry name" value="PTPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1150:FF:000005">
        <property type="entry name" value="Serine/threonine-protein phosphatase 2A activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004327">
        <property type="entry name" value="Phstyr_phstse_ac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043170">
        <property type="entry name" value="PTPA_C_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037218">
        <property type="entry name" value="PTPA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10012">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10012:SF0">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 2A ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03095">
        <property type="entry name" value="PTPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016325">
        <property type="entry name" value="Phstyr_phstse_ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140984">
        <property type="entry name" value="PTPA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0697">Rotamase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="318" mass="37149" checksum="704D010948ABD139" modified="2017-02-15" version="1">MSDNSGLSYKIINDESVIKFINSPIYNEIIDFISNLNKSVVAIEMRPLENFKLANENKKSSDDFLLLSRNVYNIFQLVKNMNKCIDSCPPVKQSSRFGNKGFQNFCDEYYKEIDDNLPQILSESNIPNISEHIFQLAHYLKNSIGNKNRIDYGTGHELNFLLFLFCLNKLNFFNVSDYKHLVLVLYRQYLEGVRRIQVIYTVEPAGSRGAWGLDDFQFLVFLFGAAQLSYNRNIKTDDIEKRELVELWAPKYLYFDALKYISMLKHAPFHESSQMLYNISGVETWEKICSGLLKMYQAEIIQKRQILQHILFGKLIDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX43</accession>
    <name>A0A1J1GX43_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PPP4</name>
        <name evidence="6" type="ORF">PGAL8A_00440500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PPP phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529627.1">
        <property type="nucleotide sequence ID" value="XM_028673145.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX43"/>
    <dbReference type="GeneID" id="39732938"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00440500"/>
    <dbReference type="OMA" id="KWWFNKS"/>
    <dbReference type="OrthoDB" id="1930084at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07415">
        <property type="entry name" value="MPP_PP2A_PP4_PP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047129">
        <property type="entry name" value="PPA2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45619">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="5">
        <location>
            <begin position="110"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="307" mass="35819" checksum="0E9CD7DF20829741" modified="2017-02-15" version="1">MNTKDLEKQIEILKKCQLLGEKEVKILCNEAKALLIKEENIRYVDLPVIICGDIHGQFHDLKELFNIGNELPEVNYIFLGDYVDRGKYSIETFLLLLALKIRYPDQITLIRGNHESRQITEVYGFYDECIKKYGSINVWKYCTEVFDYLSIGALIENNYFCIHGGLSPYFDKIDELKKIKRFQEIPRSGSLCDIMWSDPSDKNGWDKSPRGAGYLFGPDTVHKFCHVNNIEIIARAHQLVMEGYKWWFNRKLVTVWSAPNYCYRCGNLASIMEIDENSIFNFKCFGPSDIENNSNEFVKKYPPIYFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX71</accession>
    <name>A0A1J1GX71_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNase III domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00465200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529874.1">
        <property type="nucleotide sequence ID" value="XM_028673419.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX71"/>
    <dbReference type="GeneID" id="39733185"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00465200"/>
    <dbReference type="OrthoDB" id="382298at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012475673" description="RNase III domain-containing protein" evidence="2">
        <location>
            <begin position="28"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="domain" description="RNase III" evidence="3">
        <location>
            <begin position="727"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="348"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="357"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="790" mass="93298" checksum="597FC4CFCAA185F7" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXF0</accession>
    <name>A0A1J1GXF0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00376200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000086">
        <property type="protein sequence ID" value="CRG97159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529962.1">
        <property type="nucleotide sequence ID" value="XM_028673517.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXF0"/>
    <dbReference type="GeneID" id="39732292"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00376200"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="296"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="334" mass="38361" checksum="93B97E9D63660C49" modified="2017-02-15" version="1">MALLYNEGCENPEKDITECNVTACVLHGSKFKSVECDPAFKKAIKYSQKNSGDNIKKNIFVFEDTPPPYKNDAKITFLSQDSNKDIVFLYEVNPKSGYASSLVFLCRFRNLKPGLSLCKQVEKTFLGRPLSFNSIDILDRDNDNKFLNGLKYLKNERHATRKARYEEIFFSKDSCHYVTDSNTSEQVCRFSVCKKYSNGGLFCKDAKFNGKLCQLEPSNGVKEPTKFIYLPNNCIKGDSNYCTPYLCQYDQPNELYPCSKLEISTIKDVVPHSQSLALASKQDRYISNEDNTSSSLIAMSFFPFLILFFFVGCYLYKVLRKNRKKKRYASYKEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXN7</accession>
    <name>A0A1J1GXN7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RNA cytidine acetyltransferase</fullName>
            <ecNumber evidence="9">2.3.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">18S rRNA cytosine acetyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PGAL8A_00479900</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a cytidine in 18S rRNA + acetyl-CoA + ATP + H2O = an N(4)-acetylcytidine in 18S rRNA + ADP + phosphate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:51424"/>
            <dbReference type="Rhea" id="RHEA-COMP:13575"/>
            <dbReference type="Rhea" id="RHEA-COMP:13576"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:74900"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a cytidine in tRNA + acetyl-CoA + ATP + H2O = an N(4)-acetylcytidine in tRNA + ADP + phosphate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53876"/>
            <dbReference type="Rhea" id="RHEA-COMP:13670"/>
            <dbReference type="Rhea" id="RHEA-COMP:13671"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:74900"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
            <location evidence="1 9">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="9"/>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530023.1">
        <property type="nucleotide sequence ID" value="XM_028673585.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXN7"/>
    <dbReference type="GeneID" id="39733332"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00479900"/>
    <dbReference type="OMA" id="HLHYIMS"/>
    <dbReference type="OrthoDB" id="10067491at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990883">
        <property type="term" value="F:18S rRNA cytidine N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051392">
        <property type="term" value="F:tRNA cytidine N4-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904812">
        <property type="term" value="P:rRNA acetylation involved in maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051391">
        <property type="term" value="P:tRNA acetylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03211">
        <property type="entry name" value="RNA_acetyltr_Nat10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033688">
        <property type="entry name" value="NAT10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007807">
        <property type="entry name" value="TcmA/NAT10_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032672">
        <property type="entry name" value="TmcA/NAT10/Kre33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013562">
        <property type="entry name" value="TmcA/NAT10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027992">
        <property type="entry name" value="tRNA_bind_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10925">
        <property type="entry name" value="N-ACETYLTRANSFERASE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10925:SF5">
        <property type="entry name" value="RNA CYTIDINE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13718">
        <property type="entry name" value="GNAT_acetyltr_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05127">
        <property type="entry name" value="NAT10_TcmA_helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08351">
        <property type="entry name" value="TmcA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13725">
        <property type="entry name" value="tRNA_bind_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 14" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3 9 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 9" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TmcA/NAT10 N-terminal" evidence="11">
        <location>
            <begin position="15"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="TcmA/NAT10 helicase" evidence="10">
        <location>
            <begin position="363"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="12">
        <location>
            <begin position="602"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="12">
        <location>
            <begin position="739"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="12">
        <location>
            <begin position="837"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="domain" description="Possible tRNA binding" evidence="13">
        <location>
            <begin position="899"/>
            <end position="1121"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="368"/>
            <end position="377"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="544"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="790"/>
            <end position="796"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="862"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF13718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF13725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG97220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1149" mass="135783" checksum="9C39D0570FF8E58F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXP9</accession>
    <name>A0A1J1GXP9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Derlin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">Der1-2</name>
        <name evidence="8" type="ORF">PGAL8A_00491900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the derlin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530142.1">
        <property type="nucleotide sequence ID" value="XM_028673717.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXP9"/>
    <dbReference type="GeneID" id="39733452"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00491900"/>
    <dbReference type="OMA" id="LWRCVTS"/>
    <dbReference type="OrthoDB" id="1716531at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007599">
        <property type="entry name" value="DER1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11009">
        <property type="entry name" value="DER1-LIKE PROTEIN, DERLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04511">
        <property type="entry name" value="DER1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="121"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="262" mass="31096" checksum="8445BEFED5CC3B2D" modified="2017-02-15" version="1">MEISGPEVWYNNLPHVTKYMITLIFLVTLLISCNLLNVIYFILDWNLIYNNYHIWRIFLNFLFIGKFSLSWVFFMSLLSQFSSSLEKNTIFTSPGSYLYFITIQCIFLSCISILFYWPRGYPFLGNSLLFAIIYYWSRREAWSQVSIYFFTVKGYQLPFALIFLHLIMGQSLWVDIMGLLSGHIYYFFREILPREGGPNILEKTPQFFDKIMLKIQEFRFMNGIRSNFSNYGYNSINNQRNINTTGTNRRVFIGRGVRLSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXQ2</accession>
    <name>A0A1J1GXQ2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00481500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530039.1">
        <property type="nucleotide sequence ID" value="XM_028673603.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXQ2"/>
    <dbReference type="GeneID" id="39733348"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00481500"/>
    <dbReference type="OMA" id="DKNHNHK"/>
    <dbReference type="OrthoDB" id="10507478at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="500"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="545"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="572"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="666"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="710"/>
            <end position="731"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="790" mass="95116" checksum="3AB257C7C4E4EA62" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXR5</accession>
    <name>A0A1J1GXR5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosome-binding factor A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00462000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529843.1">
        <property type="nucleotide sequence ID" value="XM_028673385.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXR5"/>
    <dbReference type="GeneID" id="39733153"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00462000"/>
    <dbReference type="OMA" id="IRWFKMS"/>
    <dbReference type="OrthoDB" id="418445at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000238">
        <property type="entry name" value="RbfA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023799">
        <property type="entry name" value="RbfA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02033">
        <property type="entry name" value="RBFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89919">
        <property type="entry name" value="Ribosome-binding factor A, RbfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="320"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="561" mass="67434" checksum="BE4B55352C2CCC8F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY10</accession>
    <name>A0A1J1GY10_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00492800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530151.1">
        <property type="nucleotide sequence ID" value="XM_028673727.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY10"/>
    <dbReference type="GeneID" id="39733461"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00492800"/>
    <dbReference type="OMA" id="YMCWRCD"/>
    <dbReference type="OrthoDB" id="418622at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="122" mass="14386" checksum="027789272DFFE8E1" modified="2017-02-15" version="1">MVKHKDFKKSDLIRILSSNISKERNKAVKLLKKFEPLPKKHLDNKFDTKNVIVHKYNVLKAFMCWRCDKVKQTNVKVHWDTSEGLKTICTSCHTNLLSMKEMEKVRKENSTNNEVLKKLNKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYB8</accession>
    <name>A0A1J1GYB8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00488200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530105.1">
        <property type="nucleotide sequence ID" value="XM_028673676.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYB8"/>
    <dbReference type="GeneID" id="39733415"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00488200"/>
    <dbReference type="OrthoDB" id="10314398at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="177" mass="21140" checksum="D564E2FD8E8FBE99" modified="2017-02-15" version="1">MLHSGCYNTYNLNKDKLHNYVIKNFKLLLRQKNSRTIINDNNIMCKYEKKENIFKVFNSKIIFYEPFVDISTFTLCPVYPRNFYFKFHLDWFISLIFVKKINICIYKALKLILSSNFLTFLLIVAEVVAFAESLFGYYILIIFICKKIIIPLFKVICSGIAIFLTFKYFVLFIIHIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYC6</accession>
    <name>A0A1J1GYC6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00489000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530113.1">
        <property type="nucleotide sequence ID" value="XM_028673685.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYC6"/>
    <dbReference type="GeneID" id="39733423"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00489000"/>
    <dbReference type="OrthoDB" id="371812at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="629"/>
            <end position="650"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="751" mass="89011" checksum="D55FFE7BC873F067" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYE6</accession>
    <name>A0A1J1GYE6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00324500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000051">
        <property type="protein sequence ID" value="CRG96032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528840.1">
        <property type="nucleotide sequence ID" value="XM_028672271.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYE6"/>
    <dbReference type="GeneID" id="39731778"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00324500"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="152" mass="18409" checksum="A0AA589E72CF14EB" modified="2017-02-15" version="1">MKTYTLCLKIFTFFILTWIFHCFYDYDSNRSFVDKDILQKKNMLKDKRLLAEGNISEKKQTHIKERNEHYPSGEKDNKDEKPAYFMNIYNMLYSAFFLLIYKLFPKRTNRMSNKFIDHILNVNRKNNSEPYLLPELSLNDLLIECSVTFLEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYS6</accession>
    <name>A0A1J1GYS6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00518100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530409.1">
        <property type="nucleotide sequence ID" value="XM_028674014.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYS6"/>
    <dbReference type="GeneID" id="39733714"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00518100"/>
    <dbReference type="OrthoDB" id="380399at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="256"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="649"/>
            <end position="676"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="979" mass="119258" checksum="F2B9CC146EA17F42" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZK7</accession>
    <name>A0A1J1GZK7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Radial spoke head protein 9 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00530400</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell projection</location>
            <location evidence="8">Kinocilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Flagellum axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the flagellar radial spoke RSP9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530528.1">
        <property type="nucleotide sequence ID" value="XM_028674146.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZK7"/>
    <dbReference type="GeneID" id="39733837"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00530400"/>
    <dbReference type="OMA" id="HEHIVFK"/>
    <dbReference type="OrthoDB" id="10258956at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035082">
        <property type="term" value="P:axoneme assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060294">
        <property type="term" value="P:cilium movement involved in cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044458">
        <property type="term" value="P:motile cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055316">
        <property type="entry name" value="RSP9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22069">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22069:SF0">
        <property type="entry name" value="RADIAL SPOKE HEAD PROTEIN 9 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0282">Flagellum</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="117"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="130"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG97727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="354" mass="42156" checksum="7141E30AC9A4CD91" modified="2017-02-15" version="1">MINLKNLDFHLENLCESNRCFNDEEKLGLLYGMINLEDKIKKEIYLWGKIEGVQNDYYITYYFNYDDFFPNKKFFYCNNDYEFHEIKKGNDTLIKNIEKKTPFTLFNGTPNSFYWRNDKKKMRKEKNNEDSENEESANEDSENESNESNDNENDDNENNDSENNDNENDDNENDDNENEGSENDNNKNEKNIKDKNEMVEKNENNKKDDNQNVIELERLSYIVRKIDEEAFIIPYNSVKITNNLEVKFSNFSGLNILDALKLTSWVHFRYPKNLTYDKIKNYDTFFLNNFLDSIESDNPTNMWNIKINEELSKISIINHLYPGYIFYHILNTPFYASLYIGNGISNYDLPFLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZV9</accession>
    <name>A0A1J1GZV9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphopantetheine adenylyltransferase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00044800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530814.1">
        <property type="nucleotide sequence ID" value="XM_028674464.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZV9"/>
    <dbReference type="GeneID" id="39728973"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00044800"/>
    <dbReference type="OMA" id="YCLTMSK"/>
    <dbReference type="OrthoDB" id="330671at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025224">
        <property type="entry name" value="CCAR1/CCAR2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14304">
        <property type="entry name" value="CELL DIVISION CYCLE AND APOPTOSIS REGULATOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14304:SF11">
        <property type="entry name" value="SAP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="301"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="678"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="706"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="772"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="806"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="215"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="807"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="851"/>
            <end position="865"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1278" mass="157576" checksum="D3D5558C714DB505" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZY3</accession>
    <name>A0A1J1GZY3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">SET domain protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00029200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530656.1">
        <property type="nucleotide sequence ID" value="XM_028674288.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728815"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00029200"/>
    <dbReference type="OMA" id="NGYNPFE"/>
    <dbReference type="OrthoDB" id="430364at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053010">
        <property type="entry name" value="SET_SmydA-8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46455">
        <property type="entry name" value="SET AND MYND DOMAIN CONTAINING, ARTHROPOD-SPECIFIC, MEMBER 4, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46455:SF5">
        <property type="entry name" value="SET AND MYND DOMAIN CONTAINING, ARTHROPOD-SPECIFIC, MEMBER 4, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="830"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="1189"/>
            <end position="1221"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="1222"/>
            <end position="1254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1541"/>
            <end position="1592"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="523"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1541"/>
            <end position="1562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1563"/>
            <end position="1580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1581"/>
            <end position="1591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1612" mass="188409" checksum="CEBD67CB937F5AEE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H062</accession>
    <name>A0A1J1H062_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Small ubiquitin-related modifier, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">SUMO</name>
        <name evidence="3" type="ORF">PGAL8A_00026900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530634.1">
        <property type="nucleotide sequence ID" value="XM_028674263.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H062"/>
    <dbReference type="GeneID" id="39728792"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00026900"/>
    <dbReference type="OMA" id="MKIYCAR"/>
    <dbReference type="OrthoDB" id="442921at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16116">
        <property type="entry name" value="Ubl_Smt3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000202">
        <property type="entry name" value="Small ubiquitin-related modifier I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022617">
        <property type="entry name" value="Rad60/SUMO-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10562">
        <property type="entry name" value="SMALL UBIQUITIN-RELATED MODIFIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11976">
        <property type="entry name" value="Rad60-SLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="23"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="100" mass="11208" checksum="96F541308789254C" modified="2017-02-15" version="1">MVDETSTINNTSGTTNNNQGEHIQVKVRSPDGDEVFFKIKRKTKLEKLMEVYCNRLGQSMEAVRFLYDGDRIHGDSTPDQLCIEDGDVIDAMVQQTGGNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H080</accession>
    <name>A0A1J1H080_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00058800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530950.1">
        <property type="nucleotide sequence ID" value="XM_028674615.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H080"/>
    <dbReference type="GeneID" id="39729113"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00058800"/>
    <dbReference type="OMA" id="IYAFKKQ"/>
    <dbReference type="OrthoDB" id="269872at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="225"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="471" mass="55655" checksum="E1F12279C2C5B139" modified="2017-02-15" version="1">MSTNKLKNSNLFKLESKNIEKKDEINNLKKLTSIKIVKKKVETKNEKNVDSIIDNGEKTIKKKNPKKKDTGDTDNLSLKINNDENKKVIVKRIIQKFNINNDEIDNKFNNNDIITKKNETKKKKLKEQLSKTDFLHNNNETNVEPNDENKQILKEDSENEILDSFIEKKSFLVDKKKGVKKKKVLVKKSTIIEKLKNNEKCNSTLFNNYDNELNEKKKIIETEDSEKINKELVKRKVELEELKNLHEAEINNIKEERKNEVNNLNIYIKNLNEEINVLNNSLNEELKEKTKIQQINTELMDEKLKLKEKVNSMKTKIEESNELYNLLNEKYLTLEEENRLLFEKDEQNSTKIKNLEEEKLKLEKKIEEKNILIKKKEDIITKYSNEIENYKNVLKNKGEILLNSCTIDKNSSDKSNQKEYINKLSKEKKELIHAFKKQLDLIVILKKQINLLENNKILNLTCNEFKKIVHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0E1</accession>
    <name>A0A1J1H0E1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00059900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530961.1">
        <property type="nucleotide sequence ID" value="XM_028674627.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0E1"/>
    <dbReference type="GeneID" id="39729124"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00059900"/>
    <dbReference type="OMA" id="ESASQYH"/>
    <dbReference type="OrthoDB" id="411785at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051419">
        <property type="entry name" value="Lys/N-term_MeTrsfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12176:SF80">
        <property type="entry name" value="EEF1A LYSINE METHYLTRANSFERASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12176">
        <property type="entry name" value="SAM-DEPENDENT METHYLTRANSFERASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG98164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="847" mass="100623" checksum="692EF589357230FA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0N3</accession>
    <name>A0A1J1H0N3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Calmodulin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">MTIP</name>
        <name evidence="7" type="ORF">PGAL8A_00467100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529893.1">
        <property type="nucleotide sequence ID" value="XM_028673441.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0N3"/>
    <dbReference type="GeneID" id="39733204"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00467100"/>
    <dbReference type="OMA" id="WGPGFEW"/>
    <dbReference type="OrthoDB" id="435273at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049007">
        <property type="entry name" value="MTIP_EFh"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF0">
        <property type="entry name" value="CALMODULIN LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21550">
        <property type="entry name" value="MTIP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0007">Acetylation</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="136"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="39"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="50"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00020786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="201" mass="23172" checksum="A81544D7A62CEE88" modified="2017-02-15" version="1">MEKNCPVCYFNLPDPESTLAPYDTELNYFMWGPGFEWQPEPQEKASSVEETYEESEESDADLENLDEKVDKNDAKTFFNEKSKNGKISVENASVNARKLGLAPSSTDEEKIKEKYGDNLTYDQYLEYLSLCIHDRDNTEELVKMFAHFDINATGYLSKKQMKNILTTWGDALTEEEATDALNAFSKEDKIDYKLFCEEILQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0X6</accession>
    <name>A0A1J1H0X6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00476500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529989.1">
        <property type="nucleotide sequence ID" value="XM_028673548.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0X6"/>
    <dbReference type="GeneID" id="39733298"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00476500"/>
    <dbReference type="OrthoDB" id="380479at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="85" mass="10015" checksum="207346EEA0252F7F" modified="2017-02-15" version="1" fragment="single">TISMDYWLNFARKHFSYEEPYKHIVNVNEKDSNLQIRIDNFIGVMKALDTRLTDKDLEILMQITNPEKKDTLDLKTVSQKLAQSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1J0</accession>
    <name>A0A1J1H1J0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00497800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000101">
        <property type="protein sequence ID" value="CRG97403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530205.1">
        <property type="nucleotide sequence ID" value="XM_028673787.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1J0"/>
    <dbReference type="GeneID" id="39733511"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00497800"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012294787" evidence="2">
        <location>
            <begin position="23"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="178"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="294" mass="34966" checksum="68DC282C3459B8DE" modified="2017-02-15" version="1">MKTLTLCLKITTFLLLIWMYQCFYNCDSYKTFIYKNILQTKNELKYGRVLAEGHIAGKKQTNAEGCLEERPLDNKKNICKDPDLYKDPYNYWRKVMIPQFWDRFIKETREMDSKSKLRKWNDEFNNISNTKVNDLYSISRRRNIPNEEKIKKIDSIMRELNSEFEKFLFECKKEMTGDKTESESKKDMTDNKTESESVKEMIDNKTESASKNEVTDNKTETESMNEMIENKTESESKKEITDNKTESESNKEITDNKTESESMIEVGINKIKSYKLNICKFFTKRLDNLYENKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2P7</accession>
    <name>A0A1J1H2P7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">c-Myc-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">MYCBP</name>
        <name evidence="5" type="ORF">PGAL8A_00519800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AMY1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530423.1">
        <property type="nucleotide sequence ID" value="XM_028674029.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2P7"/>
    <dbReference type="GeneID" id="39733731"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00519800"/>
    <dbReference type="OrthoDB" id="524165at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026060">
        <property type="entry name" value="AMY1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13168">
        <property type="entry name" value="ASSOCIATE OF C-MYC AMY-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13168:SF0">
        <property type="entry name" value="C-MYC-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02028">
        <property type="entry name" value="CMYCBINDINGP"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="60"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="100" mass="11959" checksum="D0AC2B4FEB67814A" modified="2017-02-15" version="1">MSDNENISNLKDEFISYLEENEVINHISRVLLKLYEEKEKPDDAIKFIRENLYSTSDISLEDLKRENLFLREENQKLTKKFEELNDTLKKLVSSQNNITY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3R4</accession>
    <name>A0A1J1H3R4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00056200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530924.1">
        <property type="nucleotide sequence ID" value="XM_028674586.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3R4"/>
    <dbReference type="GeneID" id="39729087"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00056200"/>
    <dbReference type="OrthoDB" id="369177at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG98127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="221" mass="26361" checksum="ADBD68CFE88C7CED" modified="2017-02-15" version="1">MNEENIKEKLRTSINHLNNRRLKFDIKNFPIEKTVYEIFNIFSKNLKSKLKEVLLELKKRKKNCDICSKNIDTFNPTLLYDVDVNNATFSFIRIEVCCIKCYTIKNFSIFSNKLYKNLDSSSFLNFSSIYEHYYNVNNLEIEQKNILENDINNYFIISILAKNLRWKCSTPHKTFEEFLEYSLNNYKSNQNTGNTKILKKKKKEILKIIPNNGKKKKLNHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3T2</accession>
    <name>A0A1J1H3T2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">peptidyl-tRNA hydrolase</fullName>
            <ecNumber evidence="1">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PTH2</name>
        <name evidence="6" type="ORF">PGAL8A_00057800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an N-acyl-L-alpha-aminoacyl-tRNA + H2O = an N-acyl-L-amino acid + a tRNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54448"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:13883"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59874"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:138191"/>
            <dbReference type="EC" id="3.1.1.29"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PTH2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530940.1">
        <property type="nucleotide sequence ID" value="XM_028674604.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3T2"/>
    <dbReference type="GeneID" id="39729103"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00057800"/>
    <dbReference type="OMA" id="GHAAVEC"/>
    <dbReference type="OrthoDB" id="1733656at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:peptidyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02430">
        <property type="entry name" value="PTH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1490.10:FF:000001">
        <property type="entry name" value="Peptidyl-tRNA hydrolase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1490.10">
        <property type="entry name" value="Bit1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023476">
        <property type="entry name" value="Pep_tRNA_hydro_II_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002833">
        <property type="entry name" value="PTH2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00283">
        <property type="entry name" value="arch_pth2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003314">
        <property type="entry name" value="PRK04322.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12649">
        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12649:SF11">
        <property type="entry name" value="PEPTIDYL-TRNA HYDROLASE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01981">
        <property type="entry name" value="PTH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102462">
        <property type="entry name" value="Peptidyl-tRNA hydrolase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG98143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="184" mass="21164" checksum="C7E7DB4219ECA7AA" modified="2017-02-15" version="1">MNPNYNLRFLKNDKCDNFLLLFIFICGFILGLLLKFLNSFKIKAVKDVFANINLNCDCKMVFCVRTDIKMNKGKICSQCCHACLSVYEKIIKRNNQLQKKNLSKNCSSYFEIWKKTGQKKIVLKISSLEEMYEIEKKAQMENLLTSIIIDAGRTQIDPNTPTVIAIEPVPDEIVNKITGQLKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H405</accession>
    <name>A0A1J1H405_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Reticulocyte binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00065400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028531012.1">
        <property type="nucleotide sequence ID" value="XM_028674684.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729179"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00065400"/>
    <dbReference type="OMA" id="VINQAEN"/>
    <dbReference type="OrthoDB" id="385684at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012972612" evidence="3">
        <location>
            <begin position="24"/>
            <end position="2583"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2520"/>
            <end position="2539"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="536"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="958"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1200"/>
            <end position="1234"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1288"/>
            <end position="1338"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1369"/>
            <end position="1417"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1644"/>
            <end position="1731"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1792"/>
            <end position="1829"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1978"/>
            <end position="2012"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2336"/>
            <end position="2370"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2447"/>
            <end position="2490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG98215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2583" mass="304225" checksum="7BAE744DA01478AB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2012-05-16" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>H7CDZ5</accession>
    <name>H7CDZ5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3 4">SufB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">sufB</name>
        <name evidence="4" type="ORF">PGAL8A_API04600</name>
    </gene>
    <organism evidence="3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <geneLocation type="apicoplast" evidence="3"/>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2012" name="Mol. Biol. Evol." volume="29" first="2095" last="2099">
            <title>The Plasmodium Apicoplast Genome: Conserved Structure and Close Relationship of P. ovale to Rodent Malaria Parasites.</title>
            <authorList>
                <person name="Arisue N."/>
                <person name="Hashimoto T."/>
                <person name="Mitsui H."/>
                <person name="Palacpac N.M.Q."/>
                <person name="Kaneko A."/>
                <person name="Kawai S."/>
                <person name="Hasegawa M."/>
                <person name="Tanabe K."/>
                <person name="Horii T."/>
            </authorList>
            <dbReference type="PubMed" id="22396524"/>
            <dbReference type="DOI" id="10.1093/molbev/mss082"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">A8</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron-sulfur cluster assembly SufBD family.</text>
    </comment>
    <dbReference type="EMBL" id="AB649424">
        <property type="protein sequence ID" value="BAL70765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LN835293">
        <property type="protein sequence ID" value="CRG98256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009325483.1">
        <property type="nucleotide sequence ID" value="NC_031963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="H7CDZ5"/>
    <dbReference type="GeneID" id="30315791"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_API04600"/>
    <dbReference type="OMA" id="YYSAPKQ"/>
    <dbReference type="OrthoDB" id="446132at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Apicoplast API"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055346">
        <property type="entry name" value="Fe-S_cluster_assembly_SufBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010231">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000825">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037284">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01980">
        <property type="entry name" value="sufB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30508">
        <property type="entry name" value="FES CLUSTER ASSEMBLY PROTEIN SUF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30508:SF1">
        <property type="entry name" value="UPF0051 PROTEIN ABCI8, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01458">
        <property type="entry name" value="SUFBD_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101960">
        <property type="entry name" value="Stabilizer of iron transporter SufD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0933">Apicoplast</keyword>
    <keyword evidence="3" id="KW-0934">Plastid</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SUF system FeS cluster assembly SufBD core" evidence="2">
        <location>
            <begin position="201"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00043967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAL70765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG98256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="469" mass="55542" checksum="66262E538D4CEC0F" modified="2012-05-16" version="1">MTFKQLLNIYNLNYKYQYKNKINLYLIRNGLNKNLIKNLSNNIYLYLFIYKFKIYSLKILNIFRFPDWSFFDCPNINYDNIIYYSSILKDNNLIFYLKKNLNINFLDSIVIKNNSIDIIFDSISILHTTQYFLKKFGIIFSPLFDIIYKYPLLIKKYLGTVVSYKDNFFANINSIIFSEGSFCYIPKYIKCNFNLSTYFKTNSYDFAQFERTLLIINEYSYVIYLEGCIAPIYKESQLHVAIVEIIVKNYSYVKYYTLQNWYRGDYLGNGGLYNFTTKRGICFYFSKLDWIQIEIGSIITWKYPSTILKGDFSISNFYSISFISCMQIADTGSKMYHIGSYTKSYIISKSISLNNSLNIFRGLVYIKPNSYKSYNYTECNSLIFGNNSLTITIPYIKNYNYTSYIKQEAYISKIEIIYLFLLMQRGLSISESISLLVIGFCSEVYNKLPFEFNLEIPMLFSLKIKDIFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKN6</accession>
    <name>A0A1J1GKN6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histone RNA hairpin-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">SLBP</name>
        <name evidence="4" type="ORF">PGAL8A_00066400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SLBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG92960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525782.1">
        <property type="nucleotide sequence ID" value="XM_028674778.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKN6"/>
    <dbReference type="GeneID" id="39729189"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00066400"/>
    <dbReference type="OMA" id="NEYMENQ"/>
    <dbReference type="OrthoDB" id="265795at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071204">
        <property type="term" value="C:histone pre-mRNA 3'end processing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071207">
        <property type="term" value="F:histone pre-mRNA stem-loop binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006398">
        <property type="term" value="P:mRNA 3'-end processing by stem-loop binding and cleavage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1120">
        <property type="entry name" value="Histone RNA hairpin-binding protein RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026502">
        <property type="entry name" value="SLBP1/SLBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029344">
        <property type="entry name" value="SLBP_RNA_bind"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038294">
        <property type="entry name" value="SLBP_RNA_bind_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17408">
        <property type="entry name" value="HISTONE RNA HAIRPIN-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17408:SF0">
        <property type="entry name" value="HISTONE RNA HAIRPIN-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15247">
        <property type="entry name" value="SLBP_RNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Histone RNA hairpin-binding protein RNA-binding" evidence="3">
        <location>
            <begin position="21"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF15247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG92960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="288" mass="34654" checksum="4A3214132DEAD2C7" modified="2017-02-15" version="1">MNKISNFQRNKHPFNNNELNEAQINQRLKNINLTKRLISYERYISAIPKNERSNDLKNGWHPETPRINKHLSLSQWNKEVKKWRKQVHAWGNISEEVHKYICSLSSSEKYNYLSNLKLPELSQSEIKNLKKKNEEISDIALRNILFISDKKNPDNCVDNIIIDKPLFFLPQNFNGTILNNEFIIIKQNYLEKSLFSLKNEYDENYEYLFEKYYRLYFLMKDFNLNNENREIKTNDIIVISKKKEQSKNNNNINAVNEYMENQKIEASKYLYCSSMNTEKKNEKKKRRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKV5</accession>
    <name>A0A1J1GKV5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">50S ribosomal protein L12, apicoplast, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00071800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525836.1">
        <property type="nucleotide sequence ID" value="XM_028674779.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKV5"/>
    <dbReference type="GeneID" id="39729243"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00071800"/>
    <dbReference type="OMA" id="HRRKNYL"/>
    <dbReference type="OrthoDB" id="250175at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00387">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1390.10:FF:000007">
        <property type="entry name" value="50S ribosomal protein L12, apicoplast"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.710">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00368">
        <property type="entry name" value="Ribosomal_bL12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000206">
        <property type="entry name" value="Ribosomal_bL12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013823">
        <property type="entry name" value="Ribosomal_bL12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_bL12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008932">
        <property type="entry name" value="Ribosomal_bL12_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036235">
        <property type="entry name" value="Ribosomal_bL12_oligo_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987:SF4">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL12M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00542">
        <property type="entry name" value="Ribosomal_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16320">
        <property type="entry name" value="Ribosomal_L12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="ClpS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48300">
        <property type="entry name" value="Ribosomal protein L7/12, oligomerisation (N-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="34"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein bL12 oligomerization" evidence="7">
        <location>
            <begin position="109"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein bL12 C-terminal" evidence="6">
        <location>
            <begin position="173"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="143"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="147"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="158"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="241" mass="28656" checksum="84CBFB2BA12511A4" modified="2017-02-15" version="1">MKSKGRMLINLIKKKVETFDNKKRCKFAKSFKKIAFPIFFFFFIIHIYFIECVCFKLLREQNKFNCDNYLFNKNKVTDHYSRKNDLNYRNIYKKSLFNYNRKFKLRSEKVDNIIESLKKLTLLEASELVKKIELTFSVDTKQNVDNSKNDKENKPDESDSNSNEEEEEENKVYDLILENIEPNKKIPIIKIVKEIKKDLNLKQAKDLVDNLPQTLFEKINKETADKWKAKLTEAGGTVKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL03</accession>
    <name>A0A1J1GL03_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Outer arm dynein lc3, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00070700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525825.1">
        <property type="nucleotide sequence ID" value="XM_028674309.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL03"/>
    <dbReference type="GeneID" id="39729232"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00070700"/>
    <dbReference type="OMA" id="WSNVICE"/>
    <dbReference type="OrthoDB" id="10059120at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21455">
        <property type="entry name" value="DLC-like_DYNLT1_DYNLT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.40">
        <property type="entry name" value="Tctex-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005334">
        <property type="entry name" value="Tctex-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038586">
        <property type="entry name" value="Tctex-1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21255:SF4">
        <property type="entry name" value="DYNEIN LIGHT CHAIN TCTEX-TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21255">
        <property type="entry name" value="T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03645">
        <property type="entry name" value="Tctex-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="114" mass="13791" checksum="F9F05FF04704A987" modified="2017-02-15" version="1">MRNTDTWEEKECMKQIYSIIDDTLRNKSYSNNEINQWSNVICENCMTFLCSKMLPMKYIISCYILKKDDKETSIHLSTYWDKEDKHFQICWPQDLKSCNMLCYVNIYIIKISDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL18</accession>
    <name>A0A1J1GL18_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RING zinc finger protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00077200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525887.1">
        <property type="nucleotide sequence ID" value="XM_028670100.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL18"/>
    <dbReference type="GeneID" id="39729297"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00077200"/>
    <dbReference type="OMA" id="IIYWNDC"/>
    <dbReference type="OrthoDB" id="1302410at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051834">
        <property type="entry name" value="RING_finger_E3_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45931:SF3">
        <property type="entry name" value="RING ZINC FINGER-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45931">
        <property type="entry name" value="SI:CH211-59O9.10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="120"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="143"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="208"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="256" mass="30689" checksum="B3C7D07B570690A1" modified="2017-02-15" version="1" fragment="single">ASDQEMQNNADPIMDIIATAPSDSLYFIERINLISAIISMSTSFPYLTYLIIYWNDCSCNDILRWWIVINSILQLIQAPVRFFLYFLLRKYKRENERMHIHALRRLTSSKGWKLSKRFSLLNYLWFITGTVVMVVTRKYTKNFYLWFISWTIILSCIFRVFFTIIWFCFFFPYNQNVPKKKKGVPKQFFSEVHSFKYSPDMNLKNESCSICLSEFVEKEDIIQLNCLHDFHTKCAKKWLSQRRQCPLCQRDVMKGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLI2</accession>
    <name>A0A1J1GLI2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cysteine repeat modular protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00092900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526047.1">
        <property type="nucleotide sequence ID" value="XM_028671877.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729453"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00092900"/>
    <dbReference type="OMA" id="VCNTYYL"/>
    <dbReference type="OrthoDB" id="376142at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013131280" description="Cysteine repeat modular protein 4" evidence="2">
        <location>
            <begin position="23"/>
            <end position="2062"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="2011"/>
            <end position="2032"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2062" mass="251030" checksum="B6A54161A6E875FD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLM3</accession>
    <name>A0A1J1GLM3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00082100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525939.1">
        <property type="nucleotide sequence ID" value="XM_028670677.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLM3"/>
    <dbReference type="GeneID" id="39729345"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00082100"/>
    <dbReference type="OrthoDB" id="425723at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="245" mass="28575" checksum="B487312125028D96" modified="2017-02-15" version="1">MQSLKILYLHIYENAKTKKIRKMLEKIYGKDNVLSSKNKSRTLDVLILIFVYILCIFCISISFYFLYASKMYMLVIPCIFIMIMIFLIGSIVIYEVVYQRSLVEANLLFKKFKPNVIVAFQFGCILAMNLDPPQVPMLLISPVQENLFSTKMRKKINIKDYPYIIFVHSTNDKKRSLNKTLELVKSVDKQKYRVEIVDGGYNLELLSASDYKGWIDEIYAEERVNAKLISENISDTDDGSFKNYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM78</accession>
    <name>A0A1J1GM78_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00104700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526163.1">
        <property type="nucleotide sequence ID" value="XM_028673165.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM78"/>
    <dbReference type="GeneID" id="39729572"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00104700"/>
    <dbReference type="OMA" id="YAHELIP"/>
    <dbReference type="OrthoDB" id="376275at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="60"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="297" mass="36595" checksum="179374FA73885DCB" modified="2017-02-15" version="1">MLSNIKHCKCLNLQKILKHTNIKNKYFIYFSFCNVYNEKNINYFDYDEDLKLLKRLQNNEIDDILNINDERNILKIKKKYLKLLKVYHPDVYMKEKNEKRKKNKEEIFLQIYKKYKSINEKYQNTYDTDINDESIYENEEEKSERLEKYKRYSEGKRNDVNHKYLEIYILIGILSTFCVVFLICIYLPFNIDNYKEEFHDSSENNKVEILSCFYNPAMKRYEYFSDNFLPPHPYQLYHFYKNMFPNLSLDEDILKLKYFEVVKLPKNRAKKARLLYDKKRNELIFLKKKKKIQLKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMA3</accession>
    <name>A0A1J1GMA3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00126500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526380.1">
        <property type="nucleotide sequence ID" value="XM_028674784.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMA3"/>
    <dbReference type="GeneID" id="39729790"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00126500"/>
    <dbReference type="OMA" id="GQPIMSN"/>
    <dbReference type="OrthoDB" id="372969at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013730">
        <property type="entry name" value="Fyv7/TAP26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15657">
        <property type="entry name" value="THYROID TRANSCRIPTION FACTOR 1-ASSOCIATED PROTEIN 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15657:SF1">
        <property type="entry name" value="THYROID TRANSCRIPTION FACTOR 1-ASSOCIATED PROTEIN 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08524">
        <property type="entry name" value="rRNA_processing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="228" mass="27845" checksum="8F2AEEB8915773B4" modified="2017-02-15" version="1">MKKKHHFVNKNYIKSKSYHRKKKKYFIDQKFLRKYKKSIINENKVEVTKKDPIENFFFTPIRKEKDVGKDELEEKEKKHKESYNLNIEKQNNLYRKEGSKKDNFHDKCNIIHNLNENDNSTENNEENNEENNEKKNEEKNEKKKIIIGNNMKKRKKGSIYSKEINYSNLKKKEKEMYLKEKEATLLKNEKERRKKRLIRIQKFKKLNKKTKKGQPIMSNIINHLLKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMR7</accession>
    <name>A0A1J1GMR7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cytoplasmic tRNA 2-thiolation protein 1</fullName>
            <ecNumber evidence="2">2.7.7.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Cytoplasmic tRNA adenylyltransferase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00141100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.-" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526527.1">
        <property type="nucleotide sequence ID" value="XM_028674947.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMR7"/>
    <dbReference type="GeneID" id="39729935"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00141100"/>
    <dbReference type="OMA" id="KPVRGIC"/>
    <dbReference type="OrthoDB" id="198857at2759"/>
    <dbReference type="UniPathway" id="UPA00988"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002144">
        <property type="term" value="C:cytosolic tRNA wobble base thiouridylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032447">
        <property type="term" value="P:protein urmylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002143">
        <property type="term" value="P:tRNA wobble position uridine thiolation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01713">
        <property type="entry name" value="CTU1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03053">
        <property type="entry name" value="CTU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056369">
        <property type="entry name" value="CTU1-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000541">
        <property type="entry name" value="Ncs6/Tuc1/Ctu1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020554">
        <property type="entry name" value="UPF0021_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00269">
        <property type="entry name" value="TIGR00269 family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11807">
        <property type="entry name" value="ATPASES OF THE PP SUPERFAMILY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11807:SF12">
        <property type="entry name" value="CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01263">
        <property type="entry name" value="UPF0021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="tRNA(Ile)-lysidine/2-thiocytidine synthase N-terminal" evidence="3">
        <location>
            <begin position="50"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="417" mass="48746" checksum="F9509D0829BBBEE1" modified="2017-02-15" version="1">MLCEKCNEKSICLMKPSNREKLCKECFIKNFEDEVHMTIIKKRMFEANDKICIAVSGGKDSSVLTHVLVNIKKKYNYKWDLFLLAIDEGIKGYRDDSLKVVYKLEKLYNLPLKILKFNDIFSYTMDDVVKFIGKKNNCTVCGVFRRQAMEKGALLFNATKLVTGHNADDMAETILMNLCRGDIDKLARNINDYTFTSPLNNSMEKEILTVNKKHIENNYDYMNGIENDIDKQNLLQNEIYNDKLCQVKTKDNIEKSPIQNKINDHFNNEKNISNNIINPKESEKRKNFFLPRLKPLMWCYEKEIVLYAFHLKLDYFSTECTYSPNSFRGNLRSFIKDIETINPQFILNIIHSAEFFYFNANNKKMLNVCIKCGAYTSNQVCKACLIVTGLNNYKDNSFLYSNKKKNKKKISINYEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMY0</accession>
    <name>A0A1J1GMY0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00142200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526538.1">
        <property type="nucleotide sequence ID" value="XM_028674959.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMY0"/>
    <dbReference type="GeneID" id="39729946"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00142200"/>
    <dbReference type="OMA" id="NKIDDQC"/>
    <dbReference type="OrthoDB" id="387338at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="632" mass="76031" checksum="A6200F43003EA915" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNM0</accession>
    <name>A0A1J1GNM0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00162500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526737.1">
        <property type="nucleotide sequence ID" value="XM_028675180.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNM0"/>
    <dbReference type="GeneID" id="39730150"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00162500"/>
    <dbReference type="OMA" id="YKKYYFI"/>
    <dbReference type="OrthoDB" id="372224at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052599">
        <property type="entry name" value="SLC43A_AATransporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20772:SF5">
        <property type="entry name" value="DYNEIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20772">
        <property type="entry name" value="PROTEIN FMP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="624"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="859"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="625"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="649"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="861"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="872"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="939"/>
            <end position="964"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="964" mass="114575" checksum="C43F18D5BC827726" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNM5</accession>
    <name>A0A1J1GNM5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Merozoite surface protein 10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00378500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526902.1">
        <property type="nucleotide sequence ID" value="XM_028670118.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNM5"/>
    <dbReference type="GeneID" id="39732315"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00378500"/>
    <dbReference type="OrthoDB" id="382013at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012701208" description="Merozoite surface protein 10" evidence="3">
        <location>
            <begin position="21"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="395"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="417" mass="48289" checksum="88168247ED55260C" modified="2017-02-15" version="1">MSSMLLWILTFAFFFNLICSLIASNLTTLKDEDFEIIYESHSRNLVILSQNPKKCNNDTYYINDECKIINPQIKVNMNNVETCLNKNKCSHVAKYIFENINIDITSEQIFSKKLPCNNESDEKNYECNKELFINENMKCMCCKKELSDFIKDETDNNVYEKCKNYNQYVFTDCKCLLKNVANDSNIYINNCENFTCNGGLCTLKTNGDPFCSCFDKYYFDMKKNACVKHEDENDILLYKDKNNNSEENHKNTSTINESSSNDNPVNSLTTSLTKNRENELIDNGNKKKTINNSCSKNHIKNKHGICEQKNILEESVCLRIECFNDHEKSECFCLNKNGEKIDYNTFDVSYISTCTLNNINCDNGKCNNSLKKDKLGCICDENYIYDNDLRVCINFSLRTFLNFTIIIAIYAIMSIIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNP4</accession>
    <name>A0A1J1GNP4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00164900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526761.1">
        <property type="nucleotide sequence ID" value="XM_028675206.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNP4"/>
    <dbReference type="GeneID" id="39730174"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00164900"/>
    <dbReference type="OMA" id="SDNMQNK"/>
    <dbReference type="OrthoDB" id="375678at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="132" mass="15905" checksum="B1C7048932705141" modified="2017-02-15" version="1">MSRNVDLDRLGDIFKNTLSLMKNAMQDLAKRNSTIYNLLYTSDNMQNKHDNYNELLSSEMHFDRNKIIKWVLIALIIYMAFMVFSYLFVNYILFYFVIFSICFIIIKYIVYYYNNNDIPLLQSYQYFESNGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNP7</accession>
    <name>A0A1J1GNP7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00380700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526924.1">
        <property type="nucleotide sequence ID" value="XM_028670142.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNP7"/>
    <dbReference type="GeneID" id="39732337"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00380700"/>
    <dbReference type="OrthoDB" id="391540at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="106"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="202" mass="24418" checksum="0FB0F693AF64CA83" modified="2017-02-15" version="1">MSTIEELKFIWNFLFSDITSPKNNKEIEDEKNYEENINLLKKLMKTENIKFEQKYNAINILDKLKEVEDVRYEDIFNEYAKNFLKFLKESFENVAEEIQINDKISFRRNELIKQDLNNKLQNLNNNYNLEYINLNKCLGTEDFENQLNASLKFNSLKDILSKLLIEMKEYENQYYNLSETDKFLDMKIFELESYLNKNDENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP70</accession>
    <name>A0A1J1GP70_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00379600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526913.1">
        <property type="nucleotide sequence ID" value="XM_028670130.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732326"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00379600"/>
    <dbReference type="OMA" id="HISCCLL"/>
    <dbReference type="OrthoDB" id="378331at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1193"/>
            <end position="1220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1442"/>
            <end position="1481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1206"/>
            <end position="1220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1442"/>
            <end position="1459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1463"/>
            <end position="1481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1711" mass="203983" checksum="582C5AE6DA324F95" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPN2</accession>
    <name>A0A1J1GPN2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">nicotinamidase</fullName>
            <ecNumber evidence="6">3.5.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Nicotinamide deamidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00395800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; nicotinate biosynthesis; nicotinate from nicotinamide: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.19" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527075.1">
        <property type="nucleotide sequence ID" value="XM_028670309.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPN2"/>
    <dbReference type="GeneID" id="39732488"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00395800"/>
    <dbReference type="OrthoDB" id="1739143at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008936">
        <property type="term" value="F:nicotinamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019363">
        <property type="term" value="P:pyridine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="entry name" value="Isochorismatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052347">
        <property type="entry name" value="Isochorismatase_Nicotinamidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11080:SF2">
        <property type="entry name" value="LD05707P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11080">
        <property type="entry name" value="PYRAZINAMIDASE/NICOTINAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="Isochorismatase-like hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase-like" evidence="8">
        <location>
            <begin position="284"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00039017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00043224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="406" mass="48342" checksum="356F7614DB992FA8" modified="2017-02-15" version="1">MKCFFIVDAQNDFLPQGSFNSKTEYLDVLHKINSIRLKLYNCNEENLISLKDCMKLTENKESSHDKNIEEYYKCHSEIDDEKSLDKIFIFPFFNNSINLNGYRTLQKRYKENSKKKGNFDIHFEGKNEKKSYNGDVDKYGDNINEKFIEKYDKLQGDCNLFNFSLFILSVDYHPQFHISFAETHKIIYEQICNNNLYINENKTNEKLLSFHNKNIQEGKDNESINIVDNLNYNFLKNNNINNLSDVWKNIKRIRKTKEIYKNVNSINDIKEFQKIEFLNQTIDIWPVHCVKNTRGCKVHEKLIRHLNDIIVKKAQDENKDSYTIFENEEVNENLINILKEKNVTSVYICGFIFEYCVKETALSFLKRGYETYIIEDATAYLYEREEEKNDLKKKGIKFIQSYDIFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPU6</accession>
    <name>A0A1J1GPU6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00186200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000025">
        <property type="protein sequence ID" value="CRG94467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527287.1">
        <property type="nucleotide sequence ID" value="XM_028670546.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPU6"/>
    <dbReference type="GeneID" id="39730389"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00186200"/>
    <dbReference type="OrthoDB" id="6362699at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="352"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="395" mass="46854" checksum="1ECC06B3A0C61FC7" modified="2017-02-15" version="1">MAFLYNEGCKKSEGDFSECIMNICEISLNKFEKTYCSIHPLGVYIQKHLNSDLNDPSRNVFTYEYYPPNSKSRMTILSNNDEDGILFLYEYNPYNNEYPEKTYLCRLRTTEQKITLCEAVNMEYLGRTLKFDSYDIINEENNKKNISSLKNPNHKIIKSKYDKLLFKRHPYHHIKTEYISYYNKKNILCKKINNDNMECTDANYGGRLIYLDDRYYDLNNKYLYVPNNCLGENLNSSCSPYICDIQATNEFVPCEYEEMSVVKNIRPINNIMPTKIIMPKKDMRPINEIMPCKDLMPCKYIMRHKSMLPPYNVMPMKGIRPIKNIGPNSKNPHAISLKNKDIYHENRLNNSALFAMSFMSFLVIFIFFFCLLYRTFRKKRSRLLIKHFNILMLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ06</accession>
    <name>A0A1J1GQ06_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">GTPase-activating protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00081000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525928.1">
        <property type="nucleotide sequence ID" value="XM_028670555.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ06"/>
    <dbReference type="GeneID" id="39729334"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00081000"/>
    <dbReference type="OMA" id="NEWIERC"/>
    <dbReference type="OrthoDB" id="10266696at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048205">
        <property type="term" value="P:COPI coating of Golgi vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08831">
        <property type="entry name" value="ArfGap_ArfGap2_3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45686:SF4">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45686">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00405">
        <property type="entry name" value="REVINTRACTNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Arf-GAP" evidence="6">
        <location>
            <begin position="26"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="420" mass="49024" checksum="F33C7CBA7C63479A" modified="2017-02-15" version="1">MKKNLISEILEYEQDDRGYVLDFLKDKTFKIIMSKNENKNCFDCGNKNPKWLSLTYAIFICLNCSGKHRQLGTHISFVRSTGMDKFTAKQLVRICLGGNLKASEFLKRNKDSILDYSSSNSLKYKMYLDNLLEETLIKYSNENTKNIEPDNNTNNIINVSNNQPNDLIDDNRKNEEIINEEIDDNKKEFSNSFFSFNNVKKGDMNNFVPTHFIEEKMVFNNCNKNFKAKKIDINFDDTIFEDNGIIDNVSRKNILENKNIDNSDNLLKIYDNNIEKKFDEKGNDNRYNYCDKNFNNNNIMENKKNLNIYSKSNNNNNNNLNVTTDTKLNKFKDSKSIRSDQYFYDENQRNEEVISNVPITNSISSDQYFNKNVNKKGVWNLDEQTFQNLQGLKLTAREGLSNIVAAGNEVFLKAKEWFNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ23</accession>
    <name>A0A1J1GQ23_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Vacuolar-sorting protein SNF7, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00201000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SNF7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527428.1">
        <property type="nucleotide sequence ID" value="XM_028670702.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ23"/>
    <dbReference type="GeneID" id="39730536"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00201000"/>
    <dbReference type="OMA" id="GVKQMQK"/>
    <dbReference type="OrthoDB" id="3973241at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005771">
        <property type="term" value="C:multivesicular body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032511">
        <property type="term" value="P:late endosome to vacuole transport via multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006900">
        <property type="term" value="P:vesicle budding from membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005024">
        <property type="entry name" value="Snf7_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22761">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22761:SF12">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03357">
        <property type="entry name" value="Snf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="189"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="16"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="194"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="229" mass="26799" checksum="F1439E6C45E56D2C" modified="2017-02-15" version="1">MRFFKPKKDPTLDETYGYLEKNVKNIDENIEKYNKELNIIKQKIEEEKKKNPVNKYAIDNLRTKAANIIKKKRIYESNKENTLGIQFNIDQIKFANDNVQMSIDTCKALKNTSKILKKNIKKVNISKIEKLQDDIHDYIEEAKEIGEILSSSYEIPVDLDENEIDAELSLIEDSILDENLEGENITNYLENENENEKMLQEEASVTEKSDPTIQNEVKHTEKYFTQKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ96</accession>
    <name>A0A1J1GQ96_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-f protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00187400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000025">
        <property type="protein sequence ID" value="CRG94479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527297.1">
        <property type="nucleotide sequence ID" value="XM_028670557.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ96"/>
    <dbReference type="GeneID" id="39730401"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00187400"/>
    <dbReference type="OrthoDB" id="1490254at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="594" mass="71060" checksum="FE456F17EBC5A70F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQI2</accession>
    <name>A0A1J1GQI2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00207700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527495.1">
        <property type="nucleotide sequence ID" value="XM_028670776.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730604"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00207700"/>
    <dbReference type="OMA" id="KICHDDH"/>
    <dbReference type="OrthoDB" id="378424at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053311">
        <property type="entry name" value="Mucosal_Integrity_Assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37999">
        <property type="entry name" value="MUCIN-17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37999:SF2">
        <property type="entry name" value="MUCIN-17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2037"/>
            <end position="2061"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2631"/>
            <end position="2682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2635"/>
            <end position="2649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2650"/>
            <end position="2663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2937" mass="352277" checksum="3B1A5EDCF70EDB0B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR06</accession>
    <name>A0A1J1GR06_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00229700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527714.1">
        <property type="nucleotide sequence ID" value="XM_028671019.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR06"/>
    <dbReference type="GeneID" id="39730824"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00229700"/>
    <dbReference type="OMA" id="NIHYYPY"/>
    <dbReference type="OrthoDB" id="377179at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="168" mass="20541" checksum="D3B066F7AF6CC078" modified="2017-02-15" version="1">MKMNEKEKQSFDEQPISEFDLQKVLNKFNMSDYNEDFVITNNILKYHMKSIEVYNYEKNKIYDKSELDLYKEKLINKDNVHYYPYELYFNTYKNIYKEDKMLLSIPNNIKKTKEKENDEKEEEQEDKEKEDNASNIFEEEQGSEDDYNFDYNKSEDELDNDDNDENVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR38</accession>
    <name>A0A1J1GR38_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribonuclease, putative</fullName>
            <ecNumber evidence="4">3.1.13.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00144100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.1" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526557.1">
        <property type="nucleotide sequence ID" value="XM_028674980.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729965"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00144100"/>
    <dbReference type="OMA" id="IDCEIAF"/>
    <dbReference type="OrthoDB" id="372421at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008859">
        <property type="term" value="F:exoribonuclease II activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041505">
        <property type="entry name" value="Dis3_CSD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022966">
        <property type="entry name" value="RNase_II/R_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050180">
        <property type="entry name" value="RNR_Ribonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355:SF9">
        <property type="entry name" value="DIS3-LIKE EXONUCLEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355">
        <property type="entry name" value="RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17849">
        <property type="entry name" value="OB_Dis3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01175">
        <property type="entry name" value="RIBONUCLEASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNB" evidence="3">
        <location>
            <begin position="1951"/>
            <end position="2494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="371"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="967"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1024"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1729"/>
            <end position="1858"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2108"/>
            <end position="2164"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="791"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="380"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="466"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="967"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1032"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1738"/>
            <end position="1748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1773"/>
            <end position="1853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2110"/>
            <end position="2127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2129"/>
            <end position="2142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2640" mass="316664" checksum="5B6AC5CF788AD2EB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRC2</accession>
    <name>A0A1J1GRC2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Guanylate-binding protein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00221700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527635.1">
        <property type="nucleotide sequence ID" value="XM_028670931.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730744"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00221700"/>
    <dbReference type="OMA" id="FQEFYYL"/>
    <dbReference type="OrthoDB" id="2135133at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015894">
        <property type="entry name" value="Guanylate-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23313:SF0">
        <property type="entry name" value="TESTIS-EXPRESSED PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23313">
        <property type="entry name" value="TSEC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02263">
        <property type="entry name" value="GBP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012339658" description="Guanylate-binding protein N-terminal domain-containing protein" evidence="3">
        <location>
            <begin position="21"/>
            <end position="1389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1186"/>
            <end position="1209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1216"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1253"/>
            <end position="1277"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate-binding protein N-terminal" evidence="4">
        <location>
            <begin position="189"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate-binding protein N-terminal" evidence="4">
        <location>
            <begin position="325"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="590"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="590"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1389" mass="165171" checksum="448EDDD84E404147" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRF0</accession>
    <name>A0A1J1GRF0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Nucleolar complex protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00251300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NOC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527924.1">
        <property type="nucleotide sequence ID" value="XM_028671253.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRF0"/>
    <dbReference type="GeneID" id="39731041"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00251300"/>
    <dbReference type="OrthoDB" id="392163at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030690">
        <property type="term" value="C:Noc1p-Noc2p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030691">
        <property type="term" value="C:Noc2p-Noc3p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005343">
        <property type="entry name" value="Noc2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12687">
        <property type="entry name" value="NUCLEOLAR COMPLEX 2 AND RAD4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12687:SF4">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03715">
        <property type="entry name" value="Noc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="694"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="775" mass="92815" checksum="38537C7AE8A84697" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRG4</accession>
    <name>A0A1J1GRG4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1279 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00240700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527823.1">
        <property type="nucleotide sequence ID" value="XM_028671141.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRG4"/>
    <dbReference type="GeneID" id="39730935"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00240700"/>
    <dbReference type="OMA" id="NLRIFSC"/>
    <dbReference type="OrthoDB" id="426386at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045866">
        <property type="entry name" value="FAM210A/B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009688">
        <property type="entry name" value="FAM210A/B-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21377">
        <property type="entry name" value="PROTEIN FAM210B, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21377:SF0">
        <property type="entry name" value="PROTEIN FAM210B, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06916">
        <property type="entry name" value="FAM210A-B_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="293"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1279" evidence="2">
        <location>
            <begin position="285"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="392" mass="46753" checksum="06929CBB342942B6" modified="2017-02-15" version="1">MINLRIFSCGGIIKENNKRILIKTNLNYFSTLKNHEKYYRKFICPSNKICIGPKKTFFNLNVNHINATCKIIDNCTIYNKKKILQKCVNFNSLSNNEHSDTNLFSNLKGKEEMKKNNVDDNGNNNMNIEKKKMNYDIKYLKKNENIPYDKNGKSKRNKLFKRNYLKNMHSLLLTKKIKESLNGLKSRHSYKILMKRIKIEKNKINSILIKYQIKKGNLKINFNEHIYRKAIINTKTKIFTFLKRNNNKSLMDIYYEEKKKYKLRKQKLFELQEKFIKNSKIAQSSIKKFFKKYGYVGLTTYFIIFLITFCCSYFCVHYKYISLSDLKYVSEKIHLNKYIDEDLHKKIDSLWGELLFAYIASKISEPLRIVITILITPYIAKVIRLKKKSRIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRJ8</accession>
    <name>A0A1J1GRJ8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DEAD/DEAH box ATP-dependent RNA helicase, putative</fullName>
            <ecNumber evidence="8">3.6.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00244900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.-" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527863.1">
        <property type="nucleotide sequence ID" value="XM_028671185.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRJ8"/>
    <dbReference type="GeneID" id="39730977"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00244900"/>
    <dbReference type="OMA" id="IMIFTDT"/>
    <dbReference type="OrthoDB" id="10261904at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF24">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="83"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="283"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="18"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="470" mass="54644" checksum="6A3861FBCAC1F61C" modified="2017-02-15" version="1">MSKRLLLRYSKLNRLSQIKKYLKKLLLEKKKKRKKEEEEDEEDTNEKENNNITFENLGIEDWLIKISKSVQINYPTKIQQLCLPLIIQGKNVIGTSETGSGKTICYCWSILQELNKNFFAIFALILLPTRELVFQIIEQFLLYGSKIGVKVLSCIGGYSLIEQRRNILSKPHIVIGTPGRVSDILNNCEDIKSCFKRLKFLVLDEADLLLQKCFESKLKIILDNLQKSNERRTLFFSSTITHSIQLLIKSFPNDNLMLVNANKNQKPVKNLDQRYIYVDDIAQITYLVYILKNKLTDLSGIIFTANSYKCQLIYSVLNILGNFSVECIHSSKEQKKRISSLSKFKNGLCKIMVATDIISRGIDIPRVAFVINFDFPNDTIQYIHRIGRTARANRKGLAISFIDKKDIKNFKDVKKIMKDKLKPYILDKNEVLKDMFKIGKAIKKAEIMLEEQKDIRKENEQLKYFIYHNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRL3</accession>
    <name>A0A1J1GRL3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00137900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526496.1">
        <property type="nucleotide sequence ID" value="XM_028674913.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRL3"/>
    <dbReference type="GeneID" id="39729904"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00137900"/>
    <dbReference type="OMA" id="QDISHDI"/>
    <dbReference type="OrthoDB" id="372574at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="223"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="497"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="649"/>
            <end position="676"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="985" mass="118894" checksum="41ABB031E92A73CF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRU2</accession>
    <name>A0A1J1GRU2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Signal recognition particle receptor alpha subunit, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">SRPR-alpha</name>
        <name evidence="10" type="ORF">PGAL8A_00173100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GTP-binding SRP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526845.1">
        <property type="nucleotide sequence ID" value="XM_028670054.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRU2"/>
    <dbReference type="GeneID" id="39730258"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00173100"/>
    <dbReference type="OMA" id="HLGWIDK"/>
    <dbReference type="OrthoDB" id="1727884at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005785">
        <property type="term" value="C:signal recognition particle receptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005047">
        <property type="term" value="F:signal recognition particle binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14826">
        <property type="entry name" value="SR_alpha_SRX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17876">
        <property type="entry name" value="SRalpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000188">
        <property type="entry name" value="signal recognition particle receptor subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="entry name" value="Signal recognition particle SRP54, nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007222">
        <property type="entry name" value="Sig_recog_particle_rcpt_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036225">
        <property type="entry name" value="SRP/SRP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43134">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43134:SF1">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04086">
        <property type="entry name" value="SRP-alpha_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47364">
        <property type="entry name" value="Domain of the SRP/SRP receptor G-proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRP54-type proteins GTP-binding" evidence="9">
        <location>
            <begin position="503"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="127"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG94024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="529" mass="60658" checksum="479B081AF3D13BA5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS37</accession>
    <name>A0A1J1GS37_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00008200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528126.1">
        <property type="nucleotide sequence ID" value="XM_028671478.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS37"/>
    <dbReference type="GeneID" id="39728604"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00008200"/>
    <dbReference type="OMA" id="QYRGRFE"/>
    <dbReference type="OrthoDB" id="363224at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056347">
        <property type="entry name" value="Microp_apicomplexa_8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23512">
        <property type="entry name" value="Microp_apicomplexa_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="108" mass="12828" checksum="0670304EC1BAAC6B" modified="2017-02-15" version="1">MIKLKLFKFNTAICNCSNFLVLKRYKSHLNSVSILQQFYNRLPIRKKYIKAIKKGTLIWDKGQVKIPPLKIEGYDPPKKCLSPLSKNRNNQYRGRFENLKSHRVEFQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS67</accession>
    <name>A0A1J1GS67_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pre-mRNA splicing factor, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00010400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528148.1">
        <property type="nucleotide sequence ID" value="XM_028671502.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS67"/>
    <dbReference type="GeneID" id="39728626"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00010400"/>
    <dbReference type="OMA" id="ISIRINQ"/>
    <dbReference type="OrthoDB" id="163257at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048024">
        <property type="term" value="P:regulation of mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1390.10">
        <property type="entry name" value="PWI domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002483">
        <property type="entry name" value="PWI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036483">
        <property type="entry name" value="PWI_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052225">
        <property type="entry name" value="Ser/Arg_repetitive_matrix"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23148">
        <property type="entry name" value="SERINE/ARGININE REGULATED NUCLEAR MATRIX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23148:SF0">
        <property type="entry name" value="SERINE_ARGININE REPETITIVE MATRIX PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01480">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00311">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101233">
        <property type="entry name" value="PWI domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51025">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PWI" evidence="4">
        <location>
            <begin position="28"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="185"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="508"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="121"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="269"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="296"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="324"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="348"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="380"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="421"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="439"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="463"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="527" mass="63913" checksum="5D2DCC57CC633957" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS82</accession>
    <name>A0A1J1GS82_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PIH1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00387200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526989.1">
        <property type="nucleotide sequence ID" value="XM_028670215.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS82"/>
    <dbReference type="GeneID" id="39732402"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00387200"/>
    <dbReference type="OrthoDB" id="375489at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="342" mass="40560" checksum="E7E7139FFDB46A92" modified="2017-02-15" version="1">MDLKNAECIWDALNDLCKNDRKAYDKFIKKHMDKIHKAKPVKPKFCFCVVADVEQVAIKTNINEYKEKICDYYIYIYYTNKIRAPILPKDFMNNIDSINFENIFISTSKIKGESSKDMYAEAVIHSIIYKNMNNLYFKNKIVTRILEIMNDYEKTFRNDIIVNTNTFKYIELQYVPKSCHYLNPHCIDNNSIEKNDETIDEEDIKFYNILNEKQNQNNDPINEEKKEIKIHSTSSDILNDIKLVKTTKKNNDNESTKVNIPKQIRSYHYTIIDRFLHIILTFNNISYDDIEILKKNNNIDIYVSNQSNECMSLNFKENLSDNVKAYFNEKLLKLTISIELLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS86</accession>
    <name>A0A1J1GS86_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00013000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528172.1">
        <property type="nucleotide sequence ID" value="XM_028671528.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS86"/>
    <dbReference type="GeneID" id="39728652"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00013000"/>
    <dbReference type="OMA" id="IYEECVG"/>
    <dbReference type="OrthoDB" id="377141at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013266790" evidence="1">
        <location>
            <begin position="22"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="569" mass="69119" checksum="036F5FC2124ECD45" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSB4</accession>
    <name>A0A1J1GSB4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Rhomboid protease ROM7, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00164800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526760.1">
        <property type="nucleotide sequence ID" value="XM_028675205.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSB4"/>
    <dbReference type="GeneID" id="39730173"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00164800"/>
    <dbReference type="OMA" id="KCKLDRV"/>
    <dbReference type="OrthoDB" id="418595at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43066:SF11">
        <property type="entry name" value="PEPTIDASE S54 RHOMBOID DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43066">
        <property type="entry name" value="RHOMBOID-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012768913" evidence="6">
        <location>
            <begin position="19"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="204"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="282"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="308"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S54 rhomboid" evidence="7">
        <location>
            <begin position="165"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="330" mass="39812" checksum="5588786CC2CD083C" modified="2017-02-15" version="1">MNIVILFFFSLYFLRGNSFHHNKIIYKKINTDNKSIIFKNKHKFYLLKKEKNINQLYSIRSPISNLLNNLNPTNVRRIIEVVPFDKIKNVFHGYFSYYNSLFKKCKLDRIIIALNTLLYLYLNQVDKNKEKKIFFHKGSLLEVKDEQRCEKYKCNYNDIYKNRNYKTFFTSIFIHKNILHLYFNMSSLISIYRLISLIYTNNQILIVFLLSGFLSNVFSYIYDMKQKNKNVFLKDVVDQNYVNKNYFINRSNKITCGSSSSIYSLYGMHITYIIFFYFKNRYIINTNFIYNFFYSFITSLLLENVSHFNHIFGFLCGSLFSFFIILFDKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSB7</accession>
    <name>A0A1J1GSB7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Iron-sulfur assembly protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">IscA1</name>
        <name evidence="9" type="ORF">PGAL8A_00017200</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; iron-sulfur cluster biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the HesB/IscA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528214.1">
        <property type="nucleotide sequence ID" value="XM_028671575.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSB7"/>
    <dbReference type="GeneID" id="39728694"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00017200"/>
    <dbReference type="OMA" id="SFQIHNP"/>
    <dbReference type="OrthoDB" id="1938621at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120510">
        <property type="term" value="C:mitochondrial [4Fe-4S] assembly complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.300.12:FF:000006">
        <property type="entry name" value="Iron-sulfur cluster assembly 2 mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="entry name" value="HesB-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016092">
        <property type="entry name" value="ATAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000361">
        <property type="entry name" value="ATAP_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00049">
        <property type="entry name" value="iron-sulfur cluster assembly accessory protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43011">
        <property type="entry name" value="IRON-SULFUR CLUSTER ASSEMBLY 2 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43011:SF1">
        <property type="entry name" value="IRON-SULFUR CLUSTER ASSEMBLY 2 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01521">
        <property type="entry name" value="Fe-S_biosyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="HesB-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core" evidence="8">
        <location>
            <begin position="55"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG95403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="164" mass="19040" checksum="E30F7C028DB326A7" modified="2017-02-15" version="1">MFRYLNKKCKIYNSLNFLKDYKLYFSSTESENKKSNYKEIIIESEKNKNVKDKILHLSNDAINKMKEINLKYKNSKALKICVEAGGCSGFKYSFSLIDKNQIKEKDVIVYDKECVITIDKEAVEILRNSKIHYTSNLISKKFTIENIQNVSSKCSCGNSFDINL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSL4</accession>
    <name>A0A1J1GSL4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Xrn1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00019700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'-3' exonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528239.1">
        <property type="nucleotide sequence ID" value="XM_028671603.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSL4"/>
    <dbReference type="GeneID" id="39728719"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00019700"/>
    <dbReference type="OrthoDB" id="372487at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004534">
        <property type="term" value="F:5'-3' RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027073">
        <property type="entry name" value="5_3_exoribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004859">
        <property type="entry name" value="Xrn1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341:SF7">
        <property type="entry name" value="5'-3' EXORIBONUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12341">
        <property type="entry name" value="5'-&gt;3' EXORIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03159">
        <property type="entry name" value="XRN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012068590" description="Xrn1 N-terminal domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="domain" description="Xrn1 N-terminal" evidence="3">
        <location>
            <begin position="23"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="925" mass="111406" checksum="86E3ECEF0B585F83" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSQ3</accession>
    <name>A0A1J1GSQ3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00178700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000021">
        <property type="protein sequence ID" value="CRG94075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526896.1">
        <property type="nucleotide sequence ID" value="XM_028670112.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSQ3"/>
    <dbReference type="GeneID" id="39730314"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00178700"/>
    <dbReference type="OrthoDB" id="6362699at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="323"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="355" mass="41697" checksum="AD4C10FAFF7F18EF" modified="2017-02-15" version="1">MAFLYNEGCENSDGNSTKCIMNICQISQNKFETSYCRIHPLIVYIQKHLNSDLNDPSRNVFTYEYYPPTIKSRITVLSNNDQDGILLLYEYNPYHNKYPEKTYLCRLRHIKQKITLCESVNVGYLGRTLTFDSFDIINEENTNKNIISLKNPNHKIIKSKYDKLLFKELPNQFIKTKYISHYNRRSTLCKKIDNDYMECSDANYSGRLILLDDNGYYDLNRKYLYLPNNCFEENLNSSCSPYICDNQVTKEFVPCVYEEICVVKNIRTIKNISPIKKVMPIKSIIPIENTTPIKNLMPNSENIAAISVKSQDISHENGFNRNALFAMSFMSFLVLFTFFFCLIYTIFRKKRRKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT11</accession>
    <name>A0A1J1GT11_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Actin-2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Actin II</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PGAL8A_00284100</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm. Polymerizes into longer and more stable actin filaments compared to ACT1/actin-1. Has ATPase activity. ATP hydrolysis leads to the formation of a stable intermediate ADP-inorganic phosphate (Pi) actin, which is followed by the release of Pi. ATP hydrolysis affects filament stability; ADP-bound actin depolymerizes much faster than ATP- or ADP-Pi-bound actin. Plays an essential role in male gametocyte development in the mosquito midgut, functioning in several processes including male gametocyte egress from host erythrocytes, formation of a beating flagellum and relocalization of ACT1/actin-1 to the cytoplasm. On the basal side of the mosquito midgut epithelium, required for the development of ookinetes into sporogonic oocysts.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Monomer (G-actin). Oligomer (F-actin). Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Unlike for mammalian monomeric actin, monomeric actin is able to induce oligomerization with ATP or ADP. Mg(2+), which is used to coordinate ATP, is required for polymerization.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528452.1">
        <property type="nucleotide sequence ID" value="XM_028671839.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT11"/>
    <dbReference type="GeneID" id="39731374"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00284100"/>
    <dbReference type="OMA" id="PNIMVGM"/>
    <dbReference type="OrthoDB" id="422673at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10224">
        <property type="entry name" value="ASKHA_NBD_actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000291">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000047">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000501">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000058">
        <property type="entry name" value="Putative actin-related protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00406">
        <property type="entry name" value="ACTINS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00432">
        <property type="entry name" value="ACTINS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0488">Methylation</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00056954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00063511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00074754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00075750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG95644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="376" mass="42604" checksum="E849F2FD298309F1" modified="2017-02-15" version="1">MSEESIALVVDNGSGMVKSGLAGDDAPKCVFPSIVGRPKMPNIMIGMEQKECYVGDEAQNKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVSPDEHPVLLTEAPLNPKTNRERMTQIMFETFEVPAMYVSIQAILSLYASGRTTGIVLDSGDGVSHTVPIYEGYVLPHAINRIDMAGRDLTYHMMKLFTERGHTFTTTAEREIVRDIKEKLCYIALDYDEELKKSEEHSDEIEEIYELPDGNLITVGSERFRCPEALFNPSLIGRECPGIHITAYQSIMKCDIDIRKDLYNNIVLSGGTTMYNNIGERLTKEMTNLAPSSMKIKVIAPPERKYSVWIGGSILSSLSTFQQMWITKEEYEESGPSIVHRKCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT14</accession>
    <name>A0A1J1GT14_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 16">Phosphatidate cytidylyltransferase</fullName>
            <ecNumber evidence="6 16">2.7.7.41</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">CDS</name>
        <name evidence="19" type="ORF">PGAL8A_00281500</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>a 1,2-diacyl-sn-glycero-3-phosphate + CTP + H(+) = a CDP-1,2-diacyl-sn-glycerol + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:16229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="2.7.7.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 16">Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 16">Belongs to the CDS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.41" evidence="6 16"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528426.1">
        <property type="nucleotide sequence ID" value="XM_028671811.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT14"/>
    <dbReference type="GeneID" id="39731348"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00281500"/>
    <dbReference type="OrthoDB" id="10260889at2759"/>
    <dbReference type="UniPathway" id="UPA00557">
        <property type="reaction ID" value="UER00614"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004605">
        <property type="term" value="F:phosphatidate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016024">
        <property type="term" value="P:CDP-diacylglycerol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000374">
        <property type="entry name" value="PC_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016720">
        <property type="entry name" value="PC_Trfase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13773">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13773:SF8">
        <property type="entry name" value="PHOSPHATIDATE CYTIDYLYLTRANSFERASE, PHOTORECEPTOR-SPECIFIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01148">
        <property type="entry name" value="CTP_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01315">
        <property type="entry name" value="CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 16 19" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="15" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 16 19" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 16 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="204"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="289"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="325"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="350"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="387"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="466"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU003938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="CRG95618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="615" mass="72809" checksum="7443D5A82AF9B813" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT56</accession>
    <name>A0A1J1GT56_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cysteine protease</fullName>
            <ecNumber evidence="11">3.4.22.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ATG4</name>
        <name evidence="14" type="ORF">PGAL8A_00288900</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[protein]-C-terminal L-amino acid-glycyl-phosphatidylethanolamide + H2O = [protein]-C-terminal L-amino acid-glycine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine</text>
            <dbReference type="Rhea" id="RHEA:67548"/>
            <dbReference type="Rhea" id="RHEA-COMP:17323"/>
            <dbReference type="Rhea" id="RHEA-COMP:17324"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="ChEBI" id="CHEBI:172940"/>
            <dbReference type="ChEBI" id="CHEBI:172941"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:67549"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the peptidase C54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.22.-" evidence="11"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528500.1">
        <property type="nucleotide sequence ID" value="XM_028671893.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT56"/>
    <dbReference type="GeneID" id="39731422"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00288900"/>
    <dbReference type="OMA" id="CMIRVVQ"/>
    <dbReference type="OrthoDB" id="2960936at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019786">
        <property type="term" value="F:protein-phosphatidylethanolamide deconjugating activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035973">
        <property type="term" value="P:aggrephagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005078">
        <property type="entry name" value="Peptidase_C54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046792">
        <property type="entry name" value="Peptidase_C54_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22624:SF49">
        <property type="entry name" value="CYSTEINE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22624">
        <property type="entry name" value="CYSTEINE PROTEASE ATG4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03416">
        <property type="entry name" value="Peptidase_C54"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0072">Autophagy</keyword>
    <keyword evidence="4 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 11 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 11 14" id="KW-0645">Protease</keyword>
    <keyword evidence="8 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Peptidase C54 catalytic" evidence="13">
        <location>
            <begin position="426"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C54 catalytic" evidence="13">
        <location>
            <begin position="648"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="334"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="334"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="375"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG95692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="945" mass="112526" checksum="8EB72A806653116D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTC8</accession>
    <name>A0A1J1GTC8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="7">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00290700</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="7">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528511.1">
        <property type="nucleotide sequence ID" value="XM_028671905.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTC8"/>
    <dbReference type="GeneID" id="39731440"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00290700"/>
    <dbReference type="OMA" id="QVRFMFE"/>
    <dbReference type="OrthoDB" id="10259640at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025313">
        <property type="entry name" value="SPB4-like_CTE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01178">
        <property type="entry name" value="DUF4217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 7 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="11">
        <location>
            <begin position="111"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="142"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="345"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="41"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="573"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="708"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="6">
        <location>
            <begin position="111"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG95703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="848" mass="100743" checksum="93CCDB94D6CF983F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTG9</accession>
    <name>A0A1J1GTG9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00405100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LTV1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527168.1">
        <property type="nucleotide sequence ID" value="XM_028670413.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTG9"/>
    <dbReference type="GeneID" id="39732581"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00405100"/>
    <dbReference type="OMA" id="ERRWDCE"/>
    <dbReference type="OrthoDB" id="5852896at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000056">
        <property type="term" value="P:ribosomal small subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007307">
        <property type="entry name" value="Ltv1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21531">
        <property type="entry name" value="LOW-TEMPERATURE VIABILITY PROTEIN LTV1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21531:SF0">
        <property type="entry name" value="PROTEIN LTV1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="456"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="510" mass="60864" checksum="338C4B36E361D82C" modified="2017-02-15" version="1">MKIKNKIKKVSFKDPEIYENIENDKHEFNEKPYSKNNDSISLTNEELKILLENFNPIDYGITEKLSESEKKIVIKEIYEKENVKSPTLNQNKIKNNIVIKENIKNDELKNTEVIKKDKLKKKKNKEDSLSYLDGDCYFPNDGYDYEQHLKPISKNFIEIKTKKETNFFEIKPNNEEEKEVYEAFEMDNLEELNDNFVYEAQNVNDIEKLEIDKELIWGNQDSYLFLNSIEYSNTLNNIQNGDIKYENVKEDKLYSYNYSNDIIDENVDYNNNDHIIFDKKLNSFKNIKDNDIISENEKGKKNEKNEKNFDSFKLSDLIEHKLKKDDDKNNEKKKIKKKKKINNCKSSEIFVNLNAEDKNKILQILNSQENEIINDEDNSFSEYSKEESSYDCETILTTKTNTTNHPYKLIIPKQIKAKPILNNNNINIKKKESDNKNESLKLERYLILEKIKTTRDKNETPEEKKERKKAVKEAQRLNRKLKKENSLLMKNEHYYLFIKNNSFFFFFFFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTH5</accession>
    <name>A0A1J1GTH5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Reticulocyte binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00273000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000043">
        <property type="protein sequence ID" value="CRG95530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528339.1">
        <property type="nucleotide sequence ID" value="XM_028671714.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731262"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00273000"/>
    <dbReference type="OMA" id="CDVEANL"/>
    <dbReference type="OrthoDB" id="385684at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012498252" evidence="4">
        <location>
            <begin position="24"/>
            <end position="2701"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="2638"/>
            <end position="2658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2497"/>
            <end position="2585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2606"/>
            <end position="2627"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="603"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1119"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1341"/>
            <end position="1405"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1669"/>
            <end position="1703"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1807"/>
            <end position="1911"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2067"/>
            <end position="2121"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2407"/>
            <end position="2438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2504"/>
            <end position="2522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2537"/>
            <end position="2559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2569"/>
            <end position="2585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2615"/>
            <end position="2626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2701" mass="316820" checksum="0CCAABD1D8A13E09" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="41" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTS4</accession>
    <name>A0A1J1GTS4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA replication licensing factor MCM2</fullName>
            <ecNumber evidence="2">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">MCM2</name>
        <name evidence="13" type="ORF">PGAL8A_00289400</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528505.1">
        <property type="nucleotide sequence ID" value="XM_028671898.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTS4"/>
    <dbReference type="GeneID" id="39731427"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00289400"/>
    <dbReference type="OMA" id="EYQIVNW"/>
    <dbReference type="OrthoDB" id="844at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902975">
        <property type="term" value="P:mitotic DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001141">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008045">
        <property type="entry name" value="MCM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF44">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01658">
        <property type="entry name" value="MCMPROTEIN2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="12">
        <location>
            <begin position="486"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG95697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="971" mass="111441" checksum="4174B383951FD44C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTX2</accession>
    <name>A0A1J1GTX2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NOT family protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00288800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528499.1">
        <property type="nucleotide sequence ID" value="XM_028671892.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731421"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00288800"/>
    <dbReference type="OMA" id="MNHINNM"/>
    <dbReference type="OrthoDB" id="1933107at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030015">
        <property type="term" value="C:CCR4-NOT core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000288">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.800">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007196">
        <property type="entry name" value="CCR4-Not_Not1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024557">
        <property type="entry name" value="CNOT1_dom_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040398">
        <property type="entry name" value="Not1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13162">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13162:SF8">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12842">
        <property type="entry name" value="DUF3819"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04054">
        <property type="entry name" value="Not1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCR4-NOT transcription complex subunit 1" evidence="4">
        <location>
            <begin position="2182"/>
            <end position="2326"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-Not complex component Not1 C-terminal" evidence="3">
        <location>
            <begin position="3826"/>
            <end position="4046"/>
        </location>
    </feature>
    <feature type="domain" description="CCR4-Not complex component Not1 C-terminal" evidence="3">
        <location>
            <begin position="4146"/>
            <end position="4272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="380"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1432"/>
            <end position="1522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3191"/>
            <end position="3246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3351"/>
            <end position="3372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3606"/>
            <end position="3699"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1312"/>
            <end position="1344"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="4079"/>
            <end position="4106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="203"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="392"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="404"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="538"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="648"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="675"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="697"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1432"/>
            <end position="1457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1467"/>
            <end position="1484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1504"/>
            <end position="1519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="3191"/>
            <end position="3217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="3351"/>
            <end position="3369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="3606"/>
            <end position="3657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="3680"/>
            <end position="3699"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="4279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="4279" mass="499612" checksum="4A14A0EABEF01B01" modified="2017-02-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU17</accession>
    <name>A0A1J1GU17_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00323500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000051">
        <property type="protein sequence ID" value="CRG96022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528830.1">
        <property type="nucleotide sequence ID" value="XM_028672260.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU17"/>
    <dbReference type="GeneID" id="39731768"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00323500"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="148" mass="17978" checksum="D83BB349FC287265" modified="2017-02-15" version="1">MKTFTLYLKIFTFLLLIWIFHCFYNYDSNKSLINRDILQTKIGLKHKRMLADGDKSEKKSSYIKKRVEYYPSGDMEIELYELVHLMDMYFKFYNANILSRYVEEVLFKKENEMRYKCRDKILNAYRKNISVERVLESFNCLISVVLQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU31</accession>
    <name>A0A1J1GU31_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fam-h protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00194200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000030">
        <property type="protein sequence ID" value="CRG94545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527360.1">
        <property type="nucleotide sequence ID" value="XM_028670626.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU31"/>
    <dbReference type="GeneID" id="39730468"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00194200"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="90"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="241" mass="28321" checksum="DFFCF9F4AFB5D963" modified="2017-02-15" version="1">MSTTKIYNKSRKKMMINFFIKIIIFTFLIWMLQDSSNKCKINLEKKLNLESKRSLAESKKELNSESEVIKMCISGELTFFKQRDVAKVTLHLKKKKKDESDKKVEETNEEIEEKIIEMDDLNKKLDEFNDMLEELNEMMENKLENDTLDDMDIEKGYLIETIKKKNKISFNKKKLCKYLKKLKPEPIVSILFLPFVACILSMITFATNNFQLYNITVLFLSLSLILTSILVINTKENKNVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUE4</accession>
    <name>A0A1J1GUE4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00329600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528887.1">
        <property type="nucleotide sequence ID" value="XM_028672324.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUE4"/>
    <dbReference type="GeneID" id="39731825"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00329600"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="287"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="325" mass="34484" checksum="665BE816934BA779" modified="2017-02-15" version="1">MNIEYDDTSNATISFANNSSSYEYILKQCYARIKIIAFVISISIFTFVAFILKLQYLFNYTSYSLCFPEHFLQIKSLPCNKRILTDQTKEKPFPIQELGIKNKENLIDGDVKRDVLRESTIEVERRRVRRKVREPIEGTTGGIAGGIVGGALGGITGGILITGGRIIGGTVGVTAGSVSGGVVGAAMGKSVGLVTRKLLNQTEISTYKNDEKSIREIIGGLIGGGAGGYVGGTIGGGMGGLIGALMGNPSGKFLRGISSRVTNRIPLSTGNISQEIVKEITRSAVKILGSVFGGITGGAAGMILGTIAGMEINKIRREKKKILSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUI1</accession>
    <name>A0A1J1GUI1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Prefoldin, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00334800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prefoldin subunit alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528938.1">
        <property type="nucleotide sequence ID" value="XM_028672380.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUI1"/>
    <dbReference type="GeneID" id="39731878"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00334800"/>
    <dbReference type="OMA" id="WSAKCAD"/>
    <dbReference type="OrthoDB" id="433124at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990113">
        <property type="term" value="P:RNA polymerase I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990114">
        <property type="term" value="P:RNA polymerase II core complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990115">
        <property type="term" value="P:RNA polymerase III assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23158">
        <property type="entry name" value="Prefoldin_UXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011599">
        <property type="entry name" value="PFD_alpha_archaea"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004127">
        <property type="entry name" value="Prefoldin_subunit_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12674">
        <property type="entry name" value="PREFOLDIN SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12674:SF2">
        <property type="entry name" value="PREFOLDIN SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02996">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="153" mass="18200" checksum="FA7F04BD37870709" modified="2017-02-15" version="1">MNLYEELGNAAINEENKGFKNLILKSEHFIDNVLHQQLRERQKKRDEILQDIFDMEILIENLNLFINTKDEKEIETLTSLGCDSYAYADILNKNKIFIQIGYEFYLEMTLEDAIVFLKKKINFYEDKLTYWNKQISKIKAHIQILMRAISNLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUI6</accession>
    <name>A0A1J1GUI6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00341900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529006.1">
        <property type="nucleotide sequence ID" value="XM_028672456.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUI6"/>
    <dbReference type="GeneID" id="39731949"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00341900"/>
    <dbReference type="OMA" id="INVIMPR"/>
    <dbReference type="OrthoDB" id="449128at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="305" mass="34993" checksum="63772E4B1A2428E5" modified="2017-02-15" version="1">MILLVKIINFSVYYFLIQLYLFKHYICSVKNKNESPLDKNMNLPNGPLDLPLDRKLNIGLRKYKYNLENEEFDNHLHNEMNEDAMKLKDAIDKNSLPREEYENYSTEDELDYNFPPWLVDMIKLSNNSKNTLESLGVENLPDVNLCKQIKHLKEQMICIIEALEDIKEVYENANDITSLTARTLAGGRLAIRALSRLKTLASAVENRQLMKTLGTPMATLILLQRETTSDRNRWLSGSILTLLTDLPVVSDLADIKTGSYGHINVIMPRQSRVRNADRNILKLREGASPSSLINGYTTIQEEYTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUK4</accession>
    <name>A0A1J1GUK4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00313600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528731.1">
        <property type="nucleotide sequence ID" value="XM_028672149.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731669"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00313600"/>
    <dbReference type="OMA" id="MNKYYHH"/>
    <dbReference type="OrthoDB" id="380368at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="279"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1409" mass="167616" checksum="DD99587327A2223D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUL1</accession>
    <name>A0A1J1GUL1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00341700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529004.1">
        <property type="nucleotide sequence ID" value="XM_028672453.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731947"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00341700"/>
    <dbReference type="OrthoDB" id="5334309at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017868">
        <property type="entry name" value="Filamin/ABP280_repeat-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00630">
        <property type="entry name" value="Filamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50194">
        <property type="entry name" value="FILAMIN_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="Filamin" evidence="1">
        <location>
            <begin position="1012"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="875"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="2131"/>
            <end position="2158"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1162"/>
            <end position="1189"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1743"/>
            <end position="1791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="2131"/>
            <end position="2152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2281" mass="271495" checksum="C091DE503FBE0A4A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUL6</accession>
    <name>A0A1J1GUL6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">4-hydroxy-3-methoxy-5-polyprenylbenzoate decarboxylase</fullName>
            <ecNumber evidence="6">4.1.1.130</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Coenzyme Q biosynthesis protein 4 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">COQ4</name>
        <name evidence="7" type="ORF">PGAL8A_00339100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Lyase that catalyzes the C1-decarboxylation of 4-hydroxy-3-methoxy-5-(all-trans-polyprenyl)benzoic acid into 2-methoxy-6-(all-trans-polyprenyl)phenol during ubiquinone biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 4-hydroxy-3-methoxy-5-(all-trans-polyprenyl)benzoate + H(+) = a 2-methoxy-6-(all-trans-polyprenyl)phenol + CO2</text>
            <dbReference type="Rhea" id="RHEA:81179"/>
            <dbReference type="Rhea" id="RHEA-COMP:9551"/>
            <dbReference type="Rhea" id="RHEA-COMP:10931"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:62731"/>
            <dbReference type="ChEBI" id="CHEBI:84443"/>
            <dbReference type="EC" id="4.1.1.130"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of a multi-subunit COQ enzyme complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Mitochondrion inner membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the COQ4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.130" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528978.1">
        <property type="nucleotide sequence ID" value="XM_028672425.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUL6"/>
    <dbReference type="GeneID" id="39731921"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00339100"/>
    <dbReference type="OMA" id="QIHDIGH"/>
    <dbReference type="OrthoDB" id="4249at2759"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031314">
        <property type="term" value="C:extrinsic component of mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120539">
        <property type="term" value="F:4-hydroxy-3-methoxy-5-polyprenylbenzoate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03111">
        <property type="entry name" value="Coq4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007715">
        <property type="entry name" value="Coq4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027540">
        <property type="entry name" value="Coq4_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12922">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12922:SF7">
        <property type="entry name" value="UBIQUINONE BIOSYNTHESIS PROTEIN COQ4 HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05019">
        <property type="entry name" value="Coq4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2 6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0830">Ubiquinone</keyword>
    <keyword evidence="1 6" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="355" mass="42689" checksum="5ADA9985982489BC" modified="2017-02-15" version="1">MYNFVKIFQSNFIGINTINKLEIFLKNIFRIYRTPGRTHLLAHAADVSSIYAVKKIYNYMKNDDEGKLILKEKPLLIRQEICFNELKNLPKNTLGYKYMEFLETYKIHAHDREVAHFFNDANYSYILTRYRHIHDIAHVVYNLNISIESEAALKLIELIQTKLPITLLAILVAPFMTPLYRFQYIFKDKIPKKFLSTDFDFTYNDLFNYTDELSIKQYEYNLTDYFHVDKREDPSFYYKLYKYYFDNLNNSNHVRGSIIYGFKNKSNNDIFYDKLNSEYVYIKNFEKKYLLFQYKPRKTLLKQLYPWAYKAGASITKPLHSIYIEKWLDKDIDLFRKHYNIIPLPSHLNLMAGIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUP1</accession>
    <name>A0A1J1GUP1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00242200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527837.1">
        <property type="nucleotide sequence ID" value="XM_028671157.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUP1"/>
    <dbReference type="GeneID" id="39730950"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00242200"/>
    <dbReference type="OMA" id="IWRARIF"/>
    <dbReference type="OrthoDB" id="370548at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="530" mass="64692" checksum="FE529964A98BC744" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUU8</accession>
    <name>A0A1J1GUU8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioredoxin-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">TLP1</name>
        <name evidence="2" type="ORF">PGAL8A_00221400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527632.1">
        <property type="nucleotide sequence ID" value="XM_028670928.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUU8"/>
    <dbReference type="GeneID" id="39730741"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00221400"/>
    <dbReference type="OMA" id="FHEINNE"/>
    <dbReference type="OrthoDB" id="10263751at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051766">
        <property type="entry name" value="TXND_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46135">
        <property type="entry name" value="NME/NM23 FAMILY MEMBER 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46135:SF3">
        <property type="entry name" value="NME_NM23 FAMILY MEMBER 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="14"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="121" mass="14302" checksum="2414FD1A4E7FCFC5" modified="2017-02-15" version="1">MKKIDDKIFHEINNEEEYKKLFDEKNDILYIIDIYTEWCGPCIFTFEIINKIYKSNLIFSESVKILAMCADKIASLKNYDNNSKPFYIIIKNGEIIQQIQGCNTPRIFSLIDDHLINKKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUV6</accession>
    <name>A0A1J1GUV6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="primary">CDPK5</name>
        <name evidence="19" type="ORF">PGAL8A_00248800</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527901.1">
        <property type="nucleotide sequence ID" value="XM_028671228.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUV6"/>
    <dbReference type="GeneID" id="39731016"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00248800"/>
    <dbReference type="OMA" id="TCVAYQL"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05117">
        <property type="entry name" value="STKc_CAMK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000315">
        <property type="entry name" value="Calcium-dependent protein kinase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000475">
        <property type="entry name" value="Calcium-dependent protein kinase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000003">
        <property type="entry name" value="Calmodulin A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050205">
        <property type="entry name" value="CDPK_Ser/Thr_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24349">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0106">Calcium</keyword>
    <keyword evidence="9 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="17">
        <location>
            <begin position="124"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="18">
        <location>
            <begin position="424"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="18">
        <location>
            <begin position="461"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="18">
        <location>
            <begin position="495"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="18">
        <location>
            <begin position="533"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00024334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="CRG95088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="567" mass="66279" checksum="A7D98250CD664320" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV54</accession>
    <name>A0A1J1GV54_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ubiquitin-related modifier 1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00365800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3/UBA4 homolog. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 6">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="5">C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of the MOCS3/UBA4 homolog, then thiocarboxylated (-COSH) via the rhodanese domain of the MOCS3/UBA4 homolog.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the URM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529238.1">
        <property type="nucleotide sequence ID" value="XM_028672713.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV54"/>
    <dbReference type="GeneID" id="39732188"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00365800"/>
    <dbReference type="OMA" id="QNNDKIC"/>
    <dbReference type="OrthoDB" id="10248987at2759"/>
    <dbReference type="UniPathway" id="UPA00988"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032447">
        <property type="term" value="P:protein urmylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034227">
        <property type="term" value="P:tRNA thio-modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01764">
        <property type="entry name" value="Ubl_Urm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03048">
        <property type="entry name" value="Urm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015221">
        <property type="entry name" value="Urm1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14986">
        <property type="entry name" value="RURM1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09138">
        <property type="entry name" value="Urm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="MoaD/ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="4 5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="modified residue" description="1-thioglycine" evidence="5">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <feature type="cross-link" description="Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)" evidence="5">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="126" mass="14762" checksum="13A1C2C98CDE5245" modified="2017-02-15" version="1">MKTKIELKFLGGLESYLENKSKNHVTFEIESEELNFENLIAYVRNYIIVERKDVFSDYVVRSDSSKMCKVLVDDIEYSNYNLNDKAKIKPGIIVLVNEYDWEILDTYSYKIQNNDKICFLSTLHGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVG1</accession>
    <name>A0A1J1GVG1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Serine/threonine protein kinase, putative</fullName>
            <ecNumber evidence="9">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00375400</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="9"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529334.1">
        <property type="nucleotide sequence ID" value="XM_028672819.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732284"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00375400"/>
    <dbReference type="OMA" id="EMPKIDQ"/>
    <dbReference type="OrthoDB" id="346907at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22974">
        <property type="entry name" value="MIXED LINEAGE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22974:SF23">
        <property type="entry name" value="TOUSLED-LIKE KINASE, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 9" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="1047"/>
            <end position="1317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="291"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="728"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="295"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="1076"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG96529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1323" mass="158590" checksum="A5F4EA9645D6669C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVG2</accession>
    <name>A0A1J1GVG2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Heat shock protein 90, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00344800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529035.1">
        <property type="nucleotide sequence ID" value="XM_028672487.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVG2"/>
    <dbReference type="GeneID" id="39731978"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00344800"/>
    <dbReference type="OMA" id="DHTQQNE"/>
    <dbReference type="OrthoDB" id="28737at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16927">
        <property type="entry name" value="HATPase_Hsp90-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.80:FF:000004">
        <property type="entry name" value="Heat shock protein 75 kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.790">
        <property type="entry name" value="Heat shock protein 90, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00505">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037196">
        <property type="entry name" value="HSP90_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001404">
        <property type="entry name" value="Hsp90_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020575">
        <property type="entry name" value="Hsp90_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003555">
        <property type="entry name" value="PRK05218.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11528">
        <property type="entry name" value="HEAT SHOCK PROTEIN 90 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00183">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002583">
        <property type="entry name" value="Hsp90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00775">
        <property type="entry name" value="HEATSHOCK90"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110942">
        <property type="entry name" value="HSP90 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="299"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="768"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="316"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="772"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="798"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="160"/>
            <end position="161"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="191"/>
            <end position="196"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="450"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR002583-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="814" mass="94043" checksum="EDAAF59D39A38051" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVL2</accession>
    <name>A0A1J1GVL2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA:m(4)X modification enzyme TRM13</fullName>
            <ecNumber evidence="1">2.1.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00358000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosine(4) in tRNA(His) + S-adenosyl-L-methionine = 2'-O-methyladenosine(4) in tRNA(His) + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:43196"/>
            <dbReference type="Rhea" id="RHEA-COMP:10401"/>
            <dbReference type="Rhea" id="RHEA-COMP:10402"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74477"/>
            <dbReference type="EC" id="2.1.1.225"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>cytidine(4) in tRNA(Gly)(GCC) + S-adenosyl-L-methionine = 2'-O-methylcytidine(4) in tRNA(Gly)(GCC) + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:43192"/>
            <dbReference type="Rhea" id="RHEA-COMP:10399"/>
            <dbReference type="Rhea" id="RHEA-COMP:10400"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.225"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>cytidine(4) in tRNA(Pro) + S-adenosyl-L-methionine = 2'-O-methylcytidine(4) in tRNA(Pro) + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:32767"/>
            <dbReference type="Rhea" id="RHEA-COMP:10397"/>
            <dbReference type="Rhea" id="RHEA-COMP:10398"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.225"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase TRM13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.225" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529161.1">
        <property type="nucleotide sequence ID" value="XM_028672627.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVL2"/>
    <dbReference type="GeneID" id="39732110"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00358000"/>
    <dbReference type="OrthoDB" id="258806at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106050">
        <property type="term" value="F:tRNA 2'-O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007871">
        <property type="entry name" value="Methyltransferase_TRM13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039044">
        <property type="entry name" value="Trm13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12998">
        <property type="entry name" value="TRNA:M(4)X MODIFICATION ENZYME TRM13 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12998:SF0">
        <property type="entry name" value="TRNA:M(4)X MODIFICATION ENZYME TRM13 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05206">
        <property type="entry name" value="TRM13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Methyltransferase TRM13" evidence="3">
        <location>
            <begin position="605"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="532"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU367103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="758" mass="91328" checksum="353299DB70A1D3C7" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVW7</accession>
    <name>A0A1J1GVW7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Phd finger protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00369300</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529273.1">
        <property type="nucleotide sequence ID" value="XM_028672751.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVW7"/>
    <dbReference type="GeneID" id="39732223"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00369300"/>
    <dbReference type="OMA" id="PHERTRN"/>
    <dbReference type="OrthoDB" id="5876363at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15532">
        <property type="entry name" value="PHD2_CHD_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031724">
        <property type="entry name" value="EELM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000949">
        <property type="entry name" value="ELM2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15863">
        <property type="entry name" value="EELM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51156">
        <property type="entry name" value="ELM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="7">
        <location>
            <begin position="72"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="ELM2" evidence="8">
        <location>
            <begin position="154"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="353"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="357"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG96468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="423" mass="51114" checksum="F3BCACF627ACE901" modified="2017-02-15" version="1">MEKSIVIMHDKIKRREIDKTKAKEISIIKNYGINNHKNETYDNNDKKINNKNLKPENTNLTLKNYNDNNENDSFCYECYHGGNLICCDHCIRSYHIYCLSATDRPQTNYNYWHCPLCVSIDISWKKRKKIKTINTYEKKKEKVKQKSEGSKYTSQINVGENYQVSNVSTFFLNNHSEKYDEVHKSELVYSPYLLERMKEKFLSEGQYELVIKNDYELAIFIKELAKNWKCQLGWHPFTPEYAFKILHRVDYNPKKAIELLKSSDFNFLEICDPPIRKYENKWRPRDKRGQISDSPYPSSELLQSYIKRSVEITLDEKKYNCNINEKNKYYCEINKNNIIEQNYPHERTRNALRKEVEEDEEEEEEEEEEEEEEEKEEVEEDEEEEDEEEDEEEDEEEDDEEDEEDEEYEEEEEEEEEKQIDKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW14</accession>
    <name>A0A1J1GW14_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glutamate--cysteine ligase</fullName>
            <ecNumber evidence="3">6.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Gamma-ECS</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Gamma-glutamylcysteine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00431700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glutamate--cysteine ligase type 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.2" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529540.1">
        <property type="nucleotide sequence ID" value="XM_028673048.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW14"/>
    <dbReference type="GeneID" id="39732849"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00431700"/>
    <dbReference type="OMA" id="KICTGAA"/>
    <dbReference type="OrthoDB" id="7939818at2759"/>
    <dbReference type="UniPathway" id="UPA00142">
        <property type="reaction ID" value="UER00209"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004357">
        <property type="term" value="F:glutamate-cysteine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006750">
        <property type="term" value="P:glutathione biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.960">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.590.50">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004308">
        <property type="entry name" value="GCS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11164">
        <property type="entry name" value="GLUTAMATE CYSTEINE LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11164:SF0">
        <property type="entry name" value="GLUTAMATE--CYSTEINE LIGASE CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03074">
        <property type="entry name" value="GCS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG96736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="988" mass="115604" checksum="B9A04F9920483E72" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW93</accession>
    <name>A0A1J1GW93_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00439000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529612.1">
        <property type="nucleotide sequence ID" value="XM_028673128.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW93"/>
    <dbReference type="GeneID" id="39732923"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00439000"/>
    <dbReference type="OMA" id="IKLCFAT"/>
    <dbReference type="OrthoDB" id="369085at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="51" mass="5891" checksum="1E1449AC1B4C1F49" modified="2017-02-15" version="1">MLSTIFSILITILKLCIATSPIICIVLIFVFNKNNVPDDKKRKPDFYFEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWE5</accession>
    <name>A0A1J1GWE5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00444600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529668.1">
        <property type="nucleotide sequence ID" value="XM_028673190.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWE5"/>
    <dbReference type="GeneID" id="39732979"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00444600"/>
    <dbReference type="OMA" id="FFFQSEN"/>
    <dbReference type="OrthoDB" id="381808at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="206" mass="25848" checksum="45D291060383F9C3" modified="2017-02-15" version="1">MNVFYLFCKDNYTFIYMFFILILCIAWIRFFLKKLKNKYSKFLNKENIKKNYKLILNKNNIIHKNLFKFISYNINKKNYEDRLIHRKNASFYYLKRAIFFLHNYKYLHIKKKLNFLFIRNNITDIRNLKYLTYKKVIQFKKEMNICLTEAYNTFSYKNKKELLYIYFKLYSKIFFFFQSENIYFFHFLTHVLLVSWVYTPLNLSLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWN7</accession>
    <name>A0A1J1GWN7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00446800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529690.1">
        <property type="nucleotide sequence ID" value="XM_028673215.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWN7"/>
    <dbReference type="GeneID" id="39733001"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00446800"/>
    <dbReference type="OMA" id="FNGKCYH"/>
    <dbReference type="OrthoDB" id="375059at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="183" mass="21544" checksum="EEB86966D2CAFACA" modified="2017-02-15" version="1">MDEKHFIQTFENINEDSIPSPLIKHSSECKNYNHKKNKNIDGFILESSHKTNGMKKDEDKKYFCININKFNGKCYHKKISIIDQTHLHLTLGESLIYILNIYLQKKIISKCLYNRILYSFQLAIIEILSEVKESKENKWNIKGKLINSKKENNTQLFYLENAFLSLKNIILHVPLLKIKSIDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWV8</accession>
    <name>A0A1J1GWV8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sun-family protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00452300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529746.1">
        <property type="nucleotide sequence ID" value="XM_028673277.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWV8"/>
    <dbReference type="GeneID" id="39733056"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00452300"/>
    <dbReference type="OMA" id="PDAKWKL"/>
    <dbReference type="OrthoDB" id="4418812at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009383">
        <property type="term" value="F:rRNA (cytosine-C5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000470">
        <property type="term" value="P:maturation of LSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000218">
        <property type="entry name" value="Sun-family protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1170">
        <property type="entry name" value="Sun protein, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049560">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054728">
        <property type="entry name" value="RsmB-like_ferredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807:SF54">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_82, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807">
        <property type="entry name" value="NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22458">
        <property type="entry name" value="RsmF-B_ferredox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM-dependent MTase RsmB/NOP-type" evidence="6">
        <location>
            <begin position="117"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="328"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="376" mass="43990" checksum="789C25B50D4CD4E1" modified="2017-02-15" version="1">MNSTRLRHIENALNNFNFISPLDIYMRLYFKSNNIKKKDKPYISEHVYNIIKNKTLLSYLSSPISLYTNIIKTYFSSDKWKYEMNNERIPAHVRYSFPKELYDQLVNCYGEKRTITLMSILNEKAPIFLRVNSQKISRNELYKILMSKGISVEKCVNSQHGLLLTKNQILKNIHEYKKGYFEIQDEASQIVSSKIPVKPGYKVLDYCAGSGGKTLAFSNYMENTGKIYLHDIRDKMLSQAKIRLRRAGIQNYILLNSNHILLKKLFGYMDTVIVDAPCTGTGALRRNPEMKYKFTNDKLYDYVNLQRQIFEKALLYLKKNGKIVYITCSILDAENVHQAKYFCQKHNLYLSEPPFHSLPQSKSMDGFFLAIFERKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX19</accession>
    <name>A0A1J1GX19_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00467800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529900.1">
        <property type="nucleotide sequence ID" value="XM_028673449.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX19"/>
    <dbReference type="GeneID" id="39733211"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00467800"/>
    <dbReference type="OMA" id="MGKMVIM"/>
    <dbReference type="OrthoDB" id="295715at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="245" mass="28311" checksum="0CD0627C3E58FFCB" modified="2017-02-15" version="1">MLDKNFHLIKDLKPFLNNISIQCLIIKYIDDPPDHVNNIVKYHYQIADISGSIILCIPHTLIQEELNKNNIDILSDDIEDVVDSYDDTNLNHNQNEVNINEKKHIYDINKKSSNTKTLKYFFKIGDILNIYGAVTTWSMGKMVLMPNTRIKKNSLHEIRGSIYRVGFFTMNINTEPNLSNLITSTTEKKYQLEENGTNNSNRNFSICKNTDKKNYVGNFLNNDKVSKYDIIPLLNDGDIDLSFKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXA2</accession>
    <name>A0A1J1GXA2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin-conjugating enzyme, putative</fullName>
            <ecNumber evidence="3">6.3.2.19</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00284500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.19" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528456.1">
        <property type="nucleotide sequence ID" value="XM_028671844.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXA2"/>
    <dbReference type="GeneID" id="39731378"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00284500"/>
    <dbReference type="OrthoDB" id="406833at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09212">
        <property type="entry name" value="PUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23808">
        <property type="entry name" value="UBCc_UBE2W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000072">
        <property type="entry name" value="Ubiquitin-conjugating enzyme E2 W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036339">
        <property type="entry name" value="PUB-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018997">
        <property type="entry name" value="PUB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09409">
        <property type="entry name" value="PUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00580">
        <property type="entry name" value="PUG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143503">
        <property type="entry name" value="PUG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBC core" evidence="2">
        <location>
            <begin position="157"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="159"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="301" mass="35264" checksum="B06C0EEA967515C5" modified="2017-02-15" version="1">MTTLKESISNVLSELNCDQKKEILNVLVHILRKIIENPSRAKFRSLKKDNKTFINKLLHFKGSDNILRSLGFEEDEEKWFFPLSKDDTLSRNLKEIQNYINDNLCLLYNNSESLFEKKILDTCNDYRNNLNENTYSQFNDNDKILKNNLDGLKLEGLSKRRLEKEKMELLNEKENTIQLIREYSDKWIIQIKGAENTLYSNETFKIQFKFTDKYPIESPEVIFIGEPPIHPHIYSNGHICLSILYDHWSPVLSVNAICLSIISMLSSCKKKRKPIDDILYCSAGGKVSPKNMKWMFHDDKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXD2</accession>
    <name>A0A1J1GXD2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TOG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00453000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529753.1">
        <property type="nucleotide sequence ID" value="XM_028673284.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXD2"/>
    <dbReference type="GeneID" id="39733063"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00453000"/>
    <dbReference type="OMA" id="HFLSECS"/>
    <dbReference type="OrthoDB" id="66599at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052607">
        <property type="entry name" value="CEP104-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048739">
        <property type="entry name" value="CEP104_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048738">
        <property type="entry name" value="CEP104_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13371:SF0">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 104 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13371">
        <property type="entry name" value="GLYCINE-, GLUTAMATE-, THIENYLCYCLOHEXYLPIPERIDINE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21038">
        <property type="entry name" value="CEP104_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21039">
        <property type="entry name" value="CEP104_ZnF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Centrosomal protein CEP104 N-terminal" evidence="3">
        <location>
            <begin position="47"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="Centrosomal protein CEP104 Zn finger" evidence="4">
        <location>
            <begin position="854"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="815"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="628"/>
            <end position="655"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF21038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF21039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="973" mass="114826" checksum="51378C2420959E79" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXD8</accession>
    <name>A0A1J1GXD8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">60 kDa chaperonin, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CPN60</name>
        <name evidence="6" type="ORF">PGAL8A_00453800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the chaperonin (HSP60) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529761.1">
        <property type="nucleotide sequence ID" value="XM_028673293.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXD8"/>
    <dbReference type="GeneID" id="39733071"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00453800"/>
    <dbReference type="OMA" id="CMMVDSE"/>
    <dbReference type="OrthoDB" id="496at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03344">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000001">
        <property type="entry name" value="60 kDa chaperonin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001844">
        <property type="entry name" value="Cpn60/GroEL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000592">
        <property type="entry name" value="PRK00013.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009487">
        <property type="entry name" value="PRK12849.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45633">
        <property type="entry name" value="60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00298">
        <property type="entry name" value="CHAPERONIN60"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="655"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="412"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="659"/>
            <end position="708"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="708" mass="80268" checksum="0B7460D41A765C46" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXM9</accession>
    <name>A0A1J1GXM9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Calmodulin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00490100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530124.1">
        <property type="nucleotide sequence ID" value="XM_028673697.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXM9"/>
    <dbReference type="GeneID" id="39733434"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00490100"/>
    <dbReference type="OMA" id="KIDYVML"/>
    <dbReference type="OrthoDB" id="429467at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF0">
        <property type="entry name" value="CALMODULIN LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0007">Acetylation</keyword>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="8"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="142"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00020786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="211" mass="25161" checksum="04273ABBE6DA43DE" modified="2017-02-15" version="1">MQYNFPEDKIKLIEKNFNLIDDNKDKKINENEFKTLLRLMGQTKTEKEFNTIIEEHFDDESEENENNKSENGINKESLKLGNDNHIKKLNLKINRSKDEVMGNSRNNIEDNTKMNELIKKKKKPINFEKFLKLFMLTYTEPISVDELIKSFEMFDNEKSGYINMEKFKYILTNCNEKLIDTDINLFLNSFNFKDKDKIDYVTLSKKLKNIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY06</accession>
    <name>A0A1J1GY06_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DEAD/DEAH box ATP-dependent RNA helicase, putative</fullName>
            <ecNumber evidence="9">3.6.4.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00472500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="9"/>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529947.1">
        <property type="nucleotide sequence ID" value="XM_028673501.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY06"/>
    <dbReference type="GeneID" id="39733258"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00472500"/>
    <dbReference type="OMA" id="MIDPPKQ"/>
    <dbReference type="OrthoDB" id="10259843at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050079">
        <property type="entry name" value="DEAD_box_RNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959:SF1">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47959">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE RHLE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 5 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="161"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="371"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="63"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="539"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG97144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="723" mass="85153" checksum="27D29250E8E2D2E6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY62</accession>
    <name>A0A1J1GY62_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Heat shock protein 101, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">HSP101</name>
        <name evidence="10" type="ORF">PGAL8A_00343400</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529021.1">
        <property type="nucleotide sequence ID" value="XM_028672472.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY62"/>
    <dbReference type="GeneID" id="39731964"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00343400"/>
    <dbReference type="OMA" id="VDTIRWR"/>
    <dbReference type="OrthoDB" id="47330at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19499">
        <property type="entry name" value="RecA-like_ClpB_Hsp104-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000025">
        <property type="entry name" value="ATP-dependent Clp protease subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="entry name" value="Clp, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050130">
        <property type="entry name" value="ClpA_ClpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638:SF18">
        <property type="entry name" value="HEAT SHOCK PROTEIN 104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="Double Clp-N motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="10" id="KW-0346">Stress response</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012791745" evidence="8">
        <location>
            <begin position="27"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="domain" description="Clp R" evidence="9">
        <location>
            <begin position="31"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="438"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG96216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="903" mass="103272" checksum="E5182131C3B538A6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYD0</accession>
    <name>A0A1J1GYD0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00485200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530075.1">
        <property type="nucleotide sequence ID" value="XM_028673642.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733385"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00485200"/>
    <dbReference type="OMA" id="PICSIDY"/>
    <dbReference type="OrthoDB" id="378004at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="163"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1026"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1168"/>
            <end position="1189"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="695"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="168"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="204"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="225"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="247"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="267"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="302"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="332"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1033"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1168"/>
            <end position="1186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1301" mass="152958" checksum="C6337FC96C2CD0AD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYD4</accession>
    <name>A0A1J1GYD4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">26S proteasome regulatory subunit RPN9, putative</fullName>
            <ecNumber evidence="4">3.4.25.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RPN9</name>
        <name evidence="4" type="ORF">PGAL8A_00489800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit S11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.25.1" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530121.1">
        <property type="nucleotide sequence ID" value="XM_028673694.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYD4"/>
    <dbReference type="GeneID" id="39733431"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00489800"/>
    <dbReference type="OMA" id="ANKRTIT"/>
    <dbReference type="OrthoDB" id="1093at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="C:proteasome regulatory particle, lid subcomplex"/>
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        <property type="term" value="F:hydrolase activity"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="F:structural molecule activity"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054179">
        <property type="entry name" value="PSD13_N"/>
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    <dbReference type="InterPro" id="IPR035298">
        <property type="entry name" value="PSMD13"/>
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    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
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        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10539">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10539:SF0">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
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    <dbReference type="Pfam" id="PF22037">
        <property type="entry name" value="PSD13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 4" id="KW-0647">Proteasome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="3">
        <location>
            <begin position="177"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="390" mass="46300" checksum="1961ACF51B77301F" modified="2017-02-15" version="1">MSSTEEINKLLNEKEDTLINELKEKYNFINFDEIKSYKEKKLYHELTLEIQKFVNNKNVNIKDKFRLFYTYLSPLITKLKKTIYAELLYLVTINFDTKWTVNYLKESEQNLENDKDAIIIYRCILILKYIELNDFKSCENEIENTKNMLQGVIGLNVASHKFYNFALMNYYKVLNKSDLFVKYALLYLAYTPLDDLDESDKIEIGKYICIHSIISEDVYNIGEITQLPLINVCIKNNEETKWLYQLIYVYNEGKIDAFNEIVQKYEVNIKNTILKDYKKNMLKKITLLALMDLAFRKKKQRSDISFTEIADHCKIDIKEVEKMLITAKSKNILTCKIDEIEKSVKITWVKPRVLNVDKIYFMKESIDKWITHSKNLLTYMEDLSVELLIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYF5</accession>
    <name>A0A1J1GYF5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Leucine-rich repeat protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">LRR1</name>
        <name evidence="7" type="ORF">PGAL8A_00492200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SDS22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530145.1">
        <property type="nucleotide sequence ID" value="XM_028673720.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYF5"/>
    <dbReference type="GeneID" id="39733455"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00492200"/>
    <dbReference type="OMA" id="NRIEEWN"/>
    <dbReference type="OrthoDB" id="7451790at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050576">
        <property type="entry name" value="Cilia_flagella_integrity"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003603">
        <property type="entry name" value="U2A'_phosphoprotein32A_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45973:SF23">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45973">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00019">
        <property type="entry name" value="LEURICHRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00446">
        <property type="entry name" value="LRRcap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="U2A'/phosphoprotein 32 family A C-terminal" evidence="6">
        <location>
            <begin position="279"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="310" mass="36515" checksum="8A6500681EC98FA7" modified="2017-02-15" version="1">MATYNVLGELTTFNEDETVISHQYSRIRKIENIEKCKKLKALLLISNCIDKIENLENNLELEHLELYENMIKKIENIAMLTKLKILDLSFNKIKIIENLGTLVNLEELYLSSNKISKIENLENCRKLRLLELGYNKIRKIENLENLVNLEELWLGKNKIEEMNIPLLPKLNKLSLQHNRLTKWCEKSINNILSINELYLSYNKLNCIIDNVKNLKNLKVLDLSYNEIDNIFICSELKSLDELWLNNNKINDLKMIENLNENKNLKTLYLEKNPIEEKLEKNYRQKVINILPQLKQLDALPITPLNISQKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYP8</accession>
    <name>A0A1J1GYP8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Polyadenylate-binding protein-interacting protein 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PAIP1</name>
        <name evidence="7" type="ORF">PGAL8A_00334600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic initiation factor 4G family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528936.1">
        <property type="nucleotide sequence ID" value="XM_028672378.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731876"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00334600"/>
    <dbReference type="OMA" id="ILINQCQ"/>
    <dbReference type="OrthoDB" id="514777at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016281">
        <property type="term" value="C:eukaryotic translation initiation factor 4F complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003890">
        <property type="entry name" value="MIF4G-like_typ-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23253">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23253:SF9">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00543">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MIF4G" evidence="6">
        <location>
            <begin position="3071"/>
            <end position="3298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="371"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="985"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1476"/>
            <end position="1506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1569"/>
            <end position="1674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1791"/>
            <end position="1810"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1839"/>
            <end position="1956"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="2087"/>
            <end position="2107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="2124"/>
            <end position="2144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="2156"/>
            <end position="2235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="3481"/>
            <end position="3516"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="2572"/>
            <end position="2614"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="2699"/>
            <end position="2767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="371"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="395"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="412"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="433"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="822"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="850"/>
            <end position="878"/>
        </location>
    </feature>
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        <location>
            <begin position="985"/>
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        </location>
    </feature>
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        <location>
            <begin position="1570"/>
            <end position="1589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1598"/>
            <end position="1628"/>
        </location>
    </feature>
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        <location>
            <begin position="1632"/>
            <end position="1647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1665"/>
            <end position="1674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1839"/>
            <end position="1859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1860"/>
            <end position="1870"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1871"/>
            <end position="1911"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1924"/>
            <end position="1950"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="2088"/>
            <end position="2099"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="2164"/>
            <end position="2195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="2196"/>
            <end position="2216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="2217"/>
            <end position="2233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="3481"/>
            <end position="3498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3697" mass="426000" checksum="02EBE618BF621489" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYT1</accession>
    <name>A0A1J1GYT1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RIIa domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00530100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530525.1">
        <property type="nucleotide sequence ID" value="XM_028674142.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYT1"/>
    <dbReference type="GeneID" id="39733834"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00530100"/>
    <dbReference type="OMA" id="FQYANEY"/>
    <dbReference type="OrthoDB" id="6334211at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd22973">
        <property type="entry name" value="DD_CATIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.890.10">
        <property type="entry name" value="cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047501">
        <property type="entry name" value="DD_CATIP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47391">
        <property type="entry name" value="Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="67" mass="8176" checksum="E5EC46E1C3F1002F" modified="2017-02-15" version="1">MEKDFNLIEKNNLNEEINNLKNENIKYMETHQELKDLLNDFISSILLHTPDDIFKYANEYFSYFKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYT9</accession>
    <name>A0A1J1GYT9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DUF1704 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00339700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528984.1">
        <property type="nucleotide sequence ID" value="XM_028672431.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYT9"/>
    <dbReference type="GeneID" id="39731927"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00339700"/>
    <dbReference type="OMA" id="CNHEIGT"/>
    <dbReference type="OrthoDB" id="449345at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012548">
        <property type="entry name" value="MATCAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31817">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31817:SF0">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_67, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08014">
        <property type="entry name" value="MATCAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01154">
        <property type="entry name" value="DUF1704"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="430" mass="51079" checksum="DF455AF0B2C9D64E" modified="2017-02-15" version="1">MTLSYKKLNKENENFLKKVDKKNIINNYKYNKRKKKKENDTTTIIYPNYVKLFFIPDERILNFVDHFIEILFNENTYINTIEKMISKKKCIIKNLIESQKKFFKSKMLTNPIFNYNMADDEVDNIFNKCSGDKIDFNLFYEARRIIQIAKEKFKTYDNYEKSVFYNELVTKYEFKNYIIKYLQNSGIKVKVKIEFKEHILSAVQVFKKGSTYFIQLQNQDIQKKLMKSLCDHEIGTHLLRMINHQNNNLEKYKINSCYSTEEGLAVINSMYTLRKNYLLLVTPALKYLAVCLGHFYSFSKLYIFLNDFVKDSDKCFKMCARVKRGLRDTSLPGSVYHDQLYFIGSYSILKWHKSIDFPLLYSGNIGLKHLNDITNHVDTQKNLLPSFMINKKKLNIYLKFLEKVSCINGITPEKCNFIQEKKKKNILVNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYX8</accession>
    <name>A0A1J1GYX8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fam-h protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00022100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000111">
        <property type="protein sequence ID" value="CRG97786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530587.1">
        <property type="nucleotide sequence ID" value="XM_028674212.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYX8"/>
    <dbReference type="GeneID" id="39728744"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00022100"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="176" mass="20924" checksum="24DFBF0BC5E4E8C5" modified="2017-02-15" version="1">MFAFLILILQYSNNISFESWNIKKISEGTFRLKAKRALSENIFKKSKSESTENLLDAHEKEEINVKQDEKEKDLIKSNTQKSIFHSIIIPKPSETIVEILNENNVNKQKVTKCKYKFIITFFFSLVFLSLPLYLVYLSHTEYLYNSKDHRKMYHFIMSYCFLMISCFICLLYRKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYY0</accession>
    <name>A0A1J1GYY0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00373700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529317.1">
        <property type="nucleotide sequence ID" value="XM_028672801.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYY0"/>
    <dbReference type="GeneID" id="39732267"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00373700"/>
    <dbReference type="OMA" id="YSIQYYH"/>
    <dbReference type="OrthoDB" id="377533at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="134"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="18"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="163" mass="19671" checksum="BD681DEE9F6F410A" modified="2017-02-15" version="1">MKEKLLEDALEEYRKIHKKNYEERILKENKLNEELKNEELTKEIIKNDDIYKQLQIEKDKEYSKQYYYEINNLQSRNNRSNNNSYILDNYTERLIDTPHSYLENIGTDNLLDTGGNITFTQRIRNFFLINNPRHFFVCTTFQVICNISVLILVIIFIVIFGYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ38</accession>
    <name>A0A1J1GZ38_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00507000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530298.1">
        <property type="nucleotide sequence ID" value="XM_028673891.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ38"/>
    <dbReference type="GeneID" id="39733603"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00507000"/>
    <dbReference type="OMA" id="GIKRKYQ"/>
    <dbReference type="OrthoDB" id="1936594at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044244">
        <property type="entry name" value="TTC27/Emw1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16193">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16193:SF0">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="985"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="1020"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="526"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="673"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="688"/>
            <end position="699"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1243" mass="148338" checksum="1B2228C1FEF1EB1F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ47</accession>
    <name>A0A1J1GZ47_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">tRNA (guanine(26)-N(2))-dimethyltransferase</fullName>
            <ecNumber evidence="7">2.1.1.216</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00515600</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>guanosine(26) in tRNA + 2 S-adenosyl-L-methionine = N(2)-dimethylguanosine(26) in tRNA + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:43140"/>
            <dbReference type="Rhea" id="RHEA-COMP:10359"/>
            <dbReference type="Rhea" id="RHEA-COMP:10360"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74513"/>
            <dbReference type="EC" id="2.1.1.216"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.216" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530384.1">
        <property type="nucleotide sequence ID" value="XM_028673986.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ47"/>
    <dbReference type="GeneID" id="39733689"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00515600"/>
    <dbReference type="OMA" id="YIFEGSV"/>
    <dbReference type="OrthoDB" id="6349953at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0160104">
        <property type="term" value="F:tRNA (guanine(26)-N2)-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002940">
        <property type="term" value="P:tRNA N2-guanine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.56.70:FF:000001">
        <property type="entry name" value="tRNA (guanine(26)-N(2))-dimethyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.56.70">
        <property type="entry name" value="N2,N2-dimethylguanosine tRNA methyltransferase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002905">
        <property type="entry name" value="Trm1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042296">
        <property type="entry name" value="tRNA_met_Trm1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10631">
        <property type="entry name" value="N 2 ,N 2 -DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10631:SF3">
        <property type="entry name" value="TRNA (GUANINE(26)-N(2))-DIMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02005">
        <property type="entry name" value="TRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51626">
        <property type="entry name" value="SAM_MT_TRM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 9 12" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 9" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="1 9" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="552"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="274"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="556"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="582"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00039099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00051897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG97583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="840" mass="99089" checksum="BDA92567AD18C1EB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ56</accession>
    <name>A0A1J1GZ56_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Rhomboid-like protease</fullName>
            <ecNumber evidence="11">3.4.21.105</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ROM4</name>
        <name evidence="14" type="ORF">PGAL8A_00028000</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Serine protease involved in intramembrane proteolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>Cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that are contributed by different transmembrane domains.</text>
            <dbReference type="EC" id="3.4.21.105"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Membrane</location>
            <topology evidence="2 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the peptidase S54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.105" evidence="11"/>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530645.1">
        <property type="nucleotide sequence ID" value="XM_028674275.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ56"/>
    <dbReference type="GeneID" id="39728803"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00028000"/>
    <dbReference type="OMA" id="KCTLGER"/>
    <dbReference type="OrthoDB" id="418595at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017092">
        <property type="entry name" value="Pept_S54_Rhomboid-like_Rom4/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002610">
        <property type="entry name" value="Peptidase_S54_rhomboid-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22936:SF69">
        <property type="entry name" value="RHOMBOID-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22936">
        <property type="entry name" value="RHOMBOID-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037023">
        <property type="entry name" value="Rhomboid-like_ROM4_ROM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 11 14" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="270"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="298"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="325"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="357"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="382"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="485"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S54 rhomboid" evidence="13">
        <location>
            <begin position="261"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="10">
        <location>
            <position position="330"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR037023-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG97845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="563" mass="63851" checksum="4C1414BBD7C38AE4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ63</accession>
    <name>A0A1J1GZ63_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00032000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530683.1">
        <property type="nucleotide sequence ID" value="XM_028674318.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ63"/>
    <dbReference type="GeneID" id="39728843"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00032000"/>
    <dbReference type="OMA" id="VSDDETW"/>
    <dbReference type="OrthoDB" id="538223at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050995">
        <property type="entry name" value="WD-F-box_domain-protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14604:SF3">
        <property type="entry name" value="SPERM-ASSOCIATED ANTIGEN 16 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14604">
        <property type="entry name" value="WD40 REPEAT PF20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="353"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="395"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="437"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="479"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="521"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="38"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="177"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="638" mass="74051" checksum="47ECFC1596191D12" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ81</accession>
    <name>A0A1J1GZ81_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cilia- and flagella-associated protein 91</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00518800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the CFAP91 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530416.1">
        <property type="nucleotide sequence ID" value="XM_028674022.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ81"/>
    <dbReference type="GeneID" id="39733721"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00518800"/>
    <dbReference type="OMA" id="PAQDICG"/>
    <dbReference type="OrthoDB" id="567787at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026720">
        <property type="entry name" value="CFAP91"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032840">
        <property type="entry name" value="CFAP91_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22455">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22455:SF10">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14738">
        <property type="entry name" value="CFAP91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CFAP91" evidence="8">
        <location>
            <begin position="104"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="138"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="452"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="543"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF14738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG97615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="619" mass="73872" checksum="373CED5CC6BB8DF5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ83</accession>
    <name>A0A1J1GZ83_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00511800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530346.1">
        <property type="nucleotide sequence ID" value="XM_028673944.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ83"/>
    <dbReference type="GeneID" id="39733651"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00511800"/>
    <dbReference type="OrthoDB" id="368933at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="181" mass="20958" checksum="F7A82F0E8C9F7397" modified="2017-02-15" version="1">MTGSNEDKGLIEFKNSYEMYNLNRENTLSIINEDDECIHHSVLVNRKNLDIFNIDSAMYQKLEYKRIFNLKSKIIKNEPVFASEPSISEGSLGEDEVKDNEENNITQPQIHTILCFFFPIIGCLSYILNLKYDESSLRYIYAKRALCLGSALSVIYSFIICSLLGHFLFQYNSDDLRGFTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZH2</accession>
    <name>A0A1J1GZH2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Secreted ookinete protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00520100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530426.1">
        <property type="nucleotide sequence ID" value="XM_028674033.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZH2"/>
    <dbReference type="GeneID" id="39733734"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00520100"/>
    <dbReference type="OrthoDB" id="368885at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013176093" evidence="2">
        <location>
            <begin position="26"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="193"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="223" mass="25888" checksum="36E6687CCEEDB5CC" modified="2017-02-15" version="1">MNIKMYKRVFFLLCIALLNIICAQSKNVVSSFFSFMNSKINSKKEISKIIQMGDALACLTNNENSFYNECSCSFTKIKDFEKKCSSNLKKNQEEAKNCSEEHCEICCILININNTTNSILESELSCKKKCTKSNLILNLNEDDYKLSFKKLIEFIRIFFPSNILNYYSIEKKNSPEYTNRLLDTNYQKIKEDLNSETDGDKIEEISLQSNNESEELFSPYNEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZM4</accession>
    <name>A0A1J1GZM4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glutathione synthetase</fullName>
            <shortName evidence="9">GSH-S</shortName>
            <ecNumber evidence="9">6.3.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00033500</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>gamma-L-glutamyl-L-cysteine + glycine + ATP = glutathione + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13557"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9 11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="9 11">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the eukaryotic GSH synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.3" evidence="9"/>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530697.1">
        <property type="nucleotide sequence ID" value="XM_028674334.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZM4"/>
    <dbReference type="GeneID" id="39728858"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00033500"/>
    <dbReference type="OMA" id="FEAHKNM"/>
    <dbReference type="OrthoDB" id="2020073at2759"/>
    <dbReference type="UniPathway" id="UPA00142">
        <property type="reaction ID" value="UER00210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043295">
        <property type="term" value="F:glutathione binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004363">
        <property type="term" value="F:glutathione synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1760">
        <property type="entry name" value="Glutathione synthase, substrate-binding domain superfamily, eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1080.10">
        <property type="entry name" value="Glutathione Synthetase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005615">
        <property type="entry name" value="Glutathione_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014042">
        <property type="entry name" value="Glutathione_synthase_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014709">
        <property type="entry name" value="Glutathione_synthase_C_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014049">
        <property type="entry name" value="Glutathione_synthase_N_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037013">
        <property type="entry name" value="GSH-S_sub-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004887">
        <property type="entry name" value="GSH_synth_subst-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11130">
        <property type="entry name" value="GLUTATHIONE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11130:SF0">
        <property type="entry name" value="GLUTATHIONE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03917">
        <property type="entry name" value="GSH_synth_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03199">
        <property type="entry name" value="GSH_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001558">
        <property type="entry name" value="GSHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 9" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="3 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="8 9 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 9 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutathione synthase substrate-binding" evidence="12">
        <location>
            <begin position="261"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="405"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="474"/>
            <end position="483"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="478"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="550"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="575"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="577"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="583"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR001558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001558-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001558-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG97898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="599" mass="71549" checksum="F4A39040CA79312D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H000</accession>
    <name>A0A1J1H000_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cysteine desulfurase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00063700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530995.1">
        <property type="nucleotide sequence ID" value="XM_028674665.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H000"/>
    <dbReference type="GeneID" id="39729162"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00063700"/>
    <dbReference type="OrthoDB" id="420046at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43586">
        <property type="entry name" value="CYSTEINE DESULFURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43586:SF8">
        <property type="entry name" value="CYSTEINE DESULFURASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013085611" evidence="2">
        <location>
            <begin position="17"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="Aminotransferase class V" evidence="3">
        <location>
            <begin position="69"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="Aminotransferase class V" evidence="3">
        <location>
            <begin position="440"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG98198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="551" mass="64272" checksum="511C82365017694A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0R5</accession>
    <name>A0A1J1H0R5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00470300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529925.1">
        <property type="nucleotide sequence ID" value="XM_028673476.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0R5"/>
    <dbReference type="GeneID" id="39733236"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00470300"/>
    <dbReference type="OMA" id="EYICGEI"/>
    <dbReference type="OrthoDB" id="390430at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="139" mass="16471" checksum="F0EC71FB665DE5C4" modified="2017-02-15" version="1">MKKVKNEISNFLSFDLKNKQSLINFYKVLNKEYICGEIHKNLILNPNQKSSFLYFELRQNEVVLGFKDTNNDLYQKLLKIKDSKIFGDDIKEDEDISHLIKDIKNYSYIQGGAIITFHKKLLTDYIILKLEKFKEITDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H103</accession>
    <name>A0A1J1H103_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal silencing factor RsfS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00479700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Iojap/RsfS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530021.1">
        <property type="nucleotide sequence ID" value="XM_028673583.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H103"/>
    <dbReference type="GeneID" id="39733330"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00479700"/>
    <dbReference type="OMA" id="CGPLKIH"/>
    <dbReference type="OrthoDB" id="21330at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090071">
        <property type="term" value="P:negative regulation of ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004394">
        <property type="entry name" value="Iojap/RsfS/C7orf30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21043">
        <property type="entry name" value="IOJAP SUPERFAMILY ORTHOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21043:SF0">
        <property type="entry name" value="MITOCHONDRIAL ASSEMBLY OF RIBOSOMAL LARGE SUBUNIT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02410">
        <property type="entry name" value="RsfS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="405" mass="48900" checksum="B1A338401586DA57" modified="2017-02-15" version="1">MLRKKFPFFLTKRYITEQKIFDKLKKLQNINECENLKKNESEKIEIINIDDKIYEHTMFKNSEQYENEKDEEFYENIKSLKNMNIKNFIEETLDYYCSKQFKENEWTNENINKFKDIYDTKNLNKTISNEDIEPEKKEKEKCTNENSYHIKEHNHLINENMKNEKFKDKYENLTPAQKFFEENKEKLIYESLKLYNEKKTKLSDNENNHDYYNYSNDPIVRLSENYLFDYENDENDDMKENLELEKGIMPTIEQVVCILKHEKVKNIKVIDLNKCGRRDIGMFLILCTGETAKHNKKVGKLISKIFIDLDIPYISNVVYCYCNKFDDWIISHCGPLKIHIVTKELRDFYDIENLFLYPHEHFDSQHFPSFFDYTPGIPPPYLVRSNESLDAYQNDVIYQKFISDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2D0</accession>
    <name>A0A1J1H2D0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="3">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00523500</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530460.1">
        <property type="nucleotide sequence ID" value="XM_028674070.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2D0"/>
    <dbReference type="GeneID" id="39733768"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00523500"/>
    <dbReference type="OMA" id="TDKKYYD"/>
    <dbReference type="OrthoDB" id="2083at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12235">
        <property type="entry name" value="RRM_PPIL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035542">
        <property type="entry name" value="CRIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45843">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45843:SF1">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="RRM" evidence="9">
        <location>
            <begin position="123"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="61"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="344"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="546"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="350"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="395"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="436"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="546"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="583"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="794"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="873"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="909"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="932"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="942"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="983"/>
            <end position="997"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG97659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="997" mass="121993" checksum="793A270A2A92291E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2L0</accession>
    <name>A0A1J1H2L0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00515500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530383.1">
        <property type="nucleotide sequence ID" value="XM_028673985.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2L0"/>
    <dbReference type="GeneID" id="39733688"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00515500"/>
    <dbReference type="OrthoDB" id="383194at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="26"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="506"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="152"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="758" mass="90316" checksum="47D1FE1443B5C08C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H347</accession>
    <name>A0A1J1H347_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Apicomplexan specific coiled coil protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00034500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530708.1">
        <property type="nucleotide sequence ID" value="XM_028674346.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H347"/>
    <dbReference type="GeneID" id="39728869"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00034500"/>
    <dbReference type="OMA" id="IVTKYDP"/>
    <dbReference type="OrthoDB" id="361055at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="29"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="250" mass="28934" checksum="9805A6CB9E4B4A8C" modified="2017-02-15" version="1">MTASQNNALFNSDLQTFIVTKYDPLLTIVKELNDKLQNSEKDRFRLERRIIRLEKQMLLLLEKLEVSDIIDNELREKKEEKKIHQTIEHDDNLLAPWLFSCQLGTPLSSLQVLLEFSVKDTMELNVKLWKREEDMWINFLEDLPSNSKNFLPDTLKLIDLRRAARKCLLNLCTNEILIVLRNVPGKSQAVYNTTTMTLVAILASAFYEAWKRIELTDPVSLGRIVLVLDGENVGSRLRAGNKKLKIEPLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3B5</accession>
    <name>A0A1J1H3B5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00027400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530639.1">
        <property type="nucleotide sequence ID" value="XM_028674269.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3B5"/>
    <dbReference type="GeneID" id="39728797"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00027400"/>
    <dbReference type="OMA" id="CSLIRFN"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="317" mass="38104" checksum="52EC950B7A59ECAA" modified="2017-02-15" version="1">MHFVKNFDENFLKIIKRKFAKNIENSLKPSSLRIKSDKKNFNDIINKYLPNKILKKKDKQPNKNYDSNEKYYLSSKIGRKIKFQDTNNDKNAKLLEQNNINLNDKNKTLLEENNRNDLFPKEYESNLNTLEKSDELLEISKEEYEIQKYKNKLHKKIWLTLKKNNEKEFQYYFDILNKYPLKDEVSYSILLHGNLIISNGENISESFKILNEMKLKKVHCSLIRFNERLLHSYYELIKLNARPNITQWNKVLRTVWFTSALIKARRQKYILRKIKKIKKDNSVSLSNFNNIFNIHNLEALYIENKDPLIGRNFKEIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3W6</accession>
    <name>A0A1J1H3W6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mediator of RNA polymerase II transcription subunit 10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00047700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530839.1">
        <property type="nucleotide sequence ID" value="XM_028674492.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3W6"/>
    <dbReference type="GeneID" id="39729002"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00047700"/>
    <dbReference type="OMA" id="TKEMYKY"/>
    <dbReference type="OrthoDB" id="370735at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG98042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="234" mass="27403" checksum="BA88CD67397DA3AA" modified="2017-02-15" version="1">MEESKGRIKLKINIGNDEDNNVKITEQKSSIVSDDNHSKENIKDDNSYISDKKLKEKNLEKKIISIISKLTKISCICENKRNNLNNDDNAKMCKKLVKQMYKYEKCLINLNSYINDKNHNLDDITFPSGLIKAIDNYISGDTWIYKYLLLECKKHNDKYRNLIQNISAFNSTLKSKIVNNNINDITMPIYAGVSEKKLSFLKNDEKNYYKNVHIPKELAEHYLKNFKKRKIEEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2012-05-16" modified="2026-01-28" version="48" xmlns="https://uniprot.org/uniprot">
    <accession>H7CDY7</accession>
    <name>H7CDY7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Caseinolytic protease C</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="7">Molecular chaperone, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">clpC</name>
        <name evidence="7" type="synonym">CLP</name>
        <name evidence="7" type="ORF">PGAL8A_API03500</name>
    </gene>
    <organism evidence="6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <geneLocation type="apicoplast" evidence="6"/>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2012" name="Mol. Biol. Evol." volume="29" first="2095" last="2099">
            <title>The Plasmodium Apicoplast Genome: Conserved Structure and Close Relationship of P. ovale to Rodent Malaria Parasites.</title>
            <authorList>
                <person name="Arisue N."/>
                <person name="Hashimoto T."/>
                <person name="Mitsui H."/>
                <person name="Palacpac N.M.Q."/>
                <person name="Kaneko A."/>
                <person name="Kawai S."/>
                <person name="Hasegawa M."/>
                <person name="Tanabe K."/>
                <person name="Horii T."/>
            </authorList>
            <dbReference type="PubMed" id="22396524"/>
            <dbReference type="DOI" id="10.1093/molbev/mss082"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">A8</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">8A</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AB649424">
        <property type="protein sequence ID" value="BAL70757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LN835293">
        <property type="protein sequence ID" value="CRG98246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009325473.1">
        <property type="nucleotide sequence ID" value="NC_031963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="H7CDY7"/>
    <dbReference type="GeneID" id="30315790"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_API03500"/>
    <dbReference type="OMA" id="YNIMLQI"/>
    <dbReference type="OrthoDB" id="47330at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Apicoplast API"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19499">
        <property type="entry name" value="RecA-like_ClpB_Hsp104-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000025">
        <property type="entry name" value="ATP-dependent Clp protease subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050130">
        <property type="entry name" value="ClpA_ClpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638:SF18">
        <property type="entry name" value="HEAT SHOCK PROTEIN 104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="Double Clp-N motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0933">Apicoplast</keyword>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="482"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="domain" description="Clp ATPase C-terminal" evidence="5">
        <location>
            <begin position="658"/>
            <end position="742"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAL70757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG98246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="759" mass="90291" checksum="1CCDCE8724C76A80" modified="2012-05-16" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2012-07-11" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>I2FKD5</accession>
    <name>I2FKD5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADH:ubiquinone reductase (non-electrogenic)</fullName>
            <ecNumber evidence="2">1.6.5.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ndh</name>
        <name evidence="14" type="ORF">PGAL8A_00427900</name>
    </gene>
    <organism evidence="13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2012" name="Gene" volume="502" first="36" last="39">
            <title>Age of the last common ancestor of extant Plasmodium parasite lineages.</title>
            <authorList>
                <person name="Hayakawa T."/>
                <person name="Tachibana S."/>
                <person name="Hikosaka K."/>
                <person name="Arisue N."/>
                <person name="Matsui A."/>
                <person name="Horii T."/>
                <person name="Tanabe K."/>
            </authorList>
            <dbReference type="PubMed" id="22555021"/>
            <dbReference type="DOI" id="10.1016/j.gene.2012.04.037"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="14 15" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a quinone + NADH + H(+) = a quinol + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:46160"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.6.5.9"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a ubiquinone + NADH + H(+) = a ubiquinol + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:23152"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.6.5.9" evidence="2"/>
    <dbReference type="EMBL" id="AB571144">
        <property type="protein sequence ID" value="BAM15620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="I2FKD5"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00427900"/>
    <dbReference type="OMA" id="QIPAQKD"/>
    <dbReference type="OrthoDB" id="3244603at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050136">
        <property type="term" value="F:NADH dehydrogenase (quinone) (non-electrogenic) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054585">
        <property type="entry name" value="NDH2-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054606">
        <property type="entry name" value="NDH2_hel_ins"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706:SF47">
        <property type="entry name" value="EXTERNAL NADH-UBIQUINONE OXIDOREDUCTASE 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="NADH DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22366">
        <property type="entry name" value="NDH2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22365">
        <property type="entry name" value="PfNDH2_hel_ins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="14" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="10">
        <location>
            <begin position="39"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="NADH:ubiquinone reductase helical insertion" evidence="11">
        <location>
            <begin position="361"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="External alternative NADH-ubiquinone oxidoreductase-like C-terminal" evidence="12">
        <location>
            <begin position="465"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF22365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF22366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="BAM15620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG96699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="529" mass="61080" checksum="B70FD707850CA9FB" modified="2012-07-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2012-07-11" modified="2026-01-28" version="46" xmlns="https://uniprot.org/uniprot">
    <accession>I2FKD8</accession>
    <name>I2FKD8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">ATP synthase subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">ATP5A1</name>
        <name evidence="17" type="ORF">PGAL8A_00407800</name>
    </gene>
    <organism evidence="16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2012" name="Gene" volume="502" first="36" last="39">
            <title>Age of the last common ancestor of extant Plasmodium parasite lineages.</title>
            <authorList>
                <person name="Hayakawa T."/>
                <person name="Tachibana S."/>
                <person name="Hikosaka K."/>
                <person name="Arisue N."/>
                <person name="Matsui A."/>
                <person name="Horii T."/>
                <person name="Tanabe K."/>
            </authorList>
            <dbReference type="PubMed" id="22555021"/>
            <dbReference type="DOI" id="10.1016/j.gene.2012.04.037"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="17 18" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Produces ATP from ADP in the presence of a proton gradient across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <dbReference type="EMBL" id="AB571147">
        <property type="protein sequence ID" value="BAM15623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="I2FKD8"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00407800"/>
    <dbReference type="OMA" id="INQRDNW"/>
    <dbReference type="OrthoDB" id="9805536at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18113">
        <property type="entry name" value="ATP-synt_F1_alpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18116">
        <property type="entry name" value="ATP-synt_F1_alpha_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01132">
        <property type="entry name" value="F1-ATPase_alpha_CD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.150.20:FF:000001">
        <property type="entry name" value="ATP synthase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002432">
        <property type="entry name" value="ATP synthase subunit alpha, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.150.20">
        <property type="entry name" value="ATP synthase alpha/beta chain, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01346">
        <property type="entry name" value="ATP_synth_alpha_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000793">
        <property type="entry name" value="ATP_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038376">
        <property type="entry name" value="ATP_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033732">
        <property type="entry name" value="ATP_synth_F1_a_nt-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005294">
        <property type="entry name" value="ATP_synth_F1_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00962">
        <property type="entry name" value="atpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009884">
        <property type="entry name" value="PRK13343.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48082">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48082:SF2">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00306">
        <property type="entry name" value="ATP-synt_ab_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039088">
        <property type="entry name" value="F_ATPase_subunit_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47917">
        <property type="entry name" value="C-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="N-terminal domain of alpha and beta subunits of F1 ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="6 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 12" id="KW-0139">CF(1)</keyword>
    <keyword evidence="5 11" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit N-terminal" evidence="15">
        <location>
            <begin position="55"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase F1/V1/A1 complex alpha/beta subunit nucleotide-binding" evidence="13">
        <location>
            <begin position="185"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="ATP synthase alpha subunit C-terminal" evidence="14">
        <location>
            <begin position="415"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="BAM15623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="CRG94374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="546" mass="61490" checksum="CEABD166AEFAEE73" modified="2012-07-11" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL07</accession>
    <name>A0A1J1GL07_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GINS subunit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00070800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525826.1">
        <property type="nucleotide sequence ID" value="XM_028674421.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL07"/>
    <dbReference type="GeneID" id="39729233"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00070800"/>
    <dbReference type="OrthoDB" id="363392at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="207" mass="24704" checksum="685DA1FE772BC377" modified="2017-02-15" version="1">MTAKSPCLDILPFLFREEQISNRIQNFPTETMKKAYLELKGYFEQYKIYAEKLINFSGSMNDENQRKEKLMIKLRCEYYAVIFSQASKLLHEYINFRNRLILELAINVNGLINSIHPNIIQRLNEDEQKELEKYCENIRSERTKSKLQNKFIVCFLNDLIIEDLNYEDIKKEKMPRNVFYSAGLKVSVFEDKAFDLQKCEWAKILKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL39</accession>
    <name>A0A1J1GL39_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ham1-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00084000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HAM1 NTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525958.1">
        <property type="nucleotide sequence ID" value="XM_028670888.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL39"/>
    <dbReference type="GeneID" id="39729364"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00084000"/>
    <dbReference type="OMA" id="NENDGAT"/>
    <dbReference type="OrthoDB" id="6288734at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047429">
        <property type="term" value="F:nucleoside triphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009143">
        <property type="term" value="P:nucleoside triphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00515">
        <property type="entry name" value="HAM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002637">
        <property type="entry name" value="RdgB/HAM1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11067:SF9">
        <property type="entry name" value="INOSINE TRIPHOSPHATE PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11067">
        <property type="entry name" value="INOSINE TRIPHOSPHATE PYROPHOSPHATASE/HAM1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01725">
        <property type="entry name" value="Ham1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="ITPase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="196" mass="23035" checksum="671ECE59C67AB32A" modified="2017-02-15" version="1">MDLYLVTGNKNKKMEIERMMNNELKIEFVDFDLIEIQSDNIIEINEHKVKNAFEMLNEKNSQNNKKQIVITEDTGLYIDCLNFFPGPFIKWMQKAIGSKGIYEIVSKFNDNKCHAICVYSIYDGENVHSFKGVTHGKIVEPRGSDKFSWDNIFLPNEFKKTFAEMTFCEKKEISPRFKAFVQLKEFLLKELNKYNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL67</accession>
    <name>A0A1J1GL67_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00077800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525898.1">
        <property type="nucleotide sequence ID" value="XM_028670222.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL67"/>
    <dbReference type="GeneID" id="39729303"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00077800"/>
    <dbReference type="OMA" id="VFVLMPN"/>
    <dbReference type="OrthoDB" id="328138at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="123" mass="14329" checksum="0212C9364F5DC269" modified="2017-02-15" version="1">MDINLEERSYTSPLLRYIYKKNYNLNKNSKGNNNGFIPFSIRLSSLPIKNASDNKYMSNINSLNVTNLLPLSLFSSYNSNNMSSTDILFLPKFSTFLFFTIPIFVMLPNLTLYTKHWFFFAPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL86</accession>
    <name>A0A1J1GL86_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">rRNA processing WD-repeat protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00078500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525905.1">
        <property type="nucleotide sequence ID" value="XM_028670299.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL86"/>
    <dbReference type="GeneID" id="39729310"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00078500"/>
    <dbReference type="OMA" id="VACEYIN"/>
    <dbReference type="OrthoDB" id="3142434at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034388">
        <property type="term" value="C:Pwp2p-containing subcomplex of 90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027145">
        <property type="entry name" value="PWP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19858:SF0">
        <property type="entry name" value="PERIODIC TRYPTOPHAN PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19858">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="466"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="578"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1054" mass="121836" checksum="247A7697689D09AD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL94</accession>
    <name>A0A1J1GL94_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">U3 small nucleolar RNA-associated protein 14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00079300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525913.1">
        <property type="nucleotide sequence ID" value="XM_028670388.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL94"/>
    <dbReference type="GeneID" id="39729318"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00079300"/>
    <dbReference type="OMA" id="QEPLINI"/>
    <dbReference type="OrthoDB" id="378860at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006709">
        <property type="entry name" value="SSU_processome_Utp14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14150">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14150:SF12">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 14 HOMOLOG A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04615">
        <property type="entry name" value="Utp14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="576"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="634"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="156"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1045" mass="123551" checksum="59A83031CC3BA944" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLB7</accession>
    <name>A0A1J1GLB7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Small heat shock protein HSP20, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00085700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525975.1">
        <property type="nucleotide sequence ID" value="XM_028671076.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLB7"/>
    <dbReference type="GeneID" id="39729381"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00085700"/>
    <dbReference type="OMA" id="IFKLPHN"/>
    <dbReference type="OrthoDB" id="1431247at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06464">
        <property type="entry name" value="ACD_sHsps-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031107">
        <property type="entry name" value="Small_HSP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11527">
        <property type="entry name" value="HEAT-SHOCK PROTEIN 20 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="SHSP" evidence="4">
        <location>
            <begin position="53"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="171" mass="19314" checksum="98AE578C2B685986" modified="2017-02-15" version="1">MSCLCSCSGDNGEIKLDHDYKMDIKEKPSVPKNKNALVDPNTVIEIEPDKTLKKQITFRPKVDIMFDSDKCQAILVLDIPGFKSDDIDVEIGDGILTIAGPRSQTELFETYGDNLVLHAKEREVGYFKRIFKLPNNILDDTATAMYRNGILEIKMECKQFSDVHKVEITEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLJ7</accession>
    <name>A0A1J1GLJ7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Inositol 5-phosphatase, putative</fullName>
            <ecNumber evidence="6">3.1.3.36</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00078700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.36" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525907.1">
        <property type="nucleotide sequence ID" value="XM_028670322.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLJ7"/>
    <dbReference type="GeneID" id="39729312"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00078700"/>
    <dbReference type="OrthoDB" id="405996at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043813">
        <property type="term" value="F:phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004439">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043573">
        <property type="entry name" value="Fig4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002013">
        <property type="entry name" value="SAC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45738">
        <property type="entry name" value="POLYPHOSPHOINOSITIDE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45738:SF5">
        <property type="entry name" value="POLYPHOSPHOINOSITIDE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02383">
        <property type="entry name" value="Syja_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50275">
        <property type="entry name" value="SAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="725"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="763"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="domain" description="SAC" evidence="5">
        <location>
            <begin position="135"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1229" mass="149401" checksum="FD6BDE717DAD5B73" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLR5</accession>
    <name>A0A1J1GLR5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Serine/threonine-protein phosphatase PGAM5, mitochondrial</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Serine/threonine-protein phosphatase Pgam5, mitochondrial</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">PGM2</name>
        <name evidence="6" type="ORF">PGAL8A_00086900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525987.1">
        <property type="nucleotide sequence ID" value="XM_028671211.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLR5"/>
    <dbReference type="GeneID" id="39729393"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00086900"/>
    <dbReference type="OMA" id="QLPLFAW"/>
    <dbReference type="OrthoDB" id="2118094at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090141">
        <property type="term" value="P:positive regulation of mitochondrial fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051021">
        <property type="entry name" value="Mito_Ser/Thr_phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20935">
        <property type="entry name" value="PHOSPHOGLYCERATE MUTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20935:SF0">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE PGAM5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00039765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="296" mass="35240" checksum="7E1849994496981E" modified="2017-02-15" version="1">MYQKFFNKLNFTKNARSNFFFKRKFTEAKKNIEVKYVKENKKKYIFYTTVTSISLSVLLTYVYEKYVLYKWNYKYDYYYNPNLKSIEKKEKGKNEGKKDKTVLKNIILVRHGQYERKYKDNEESKRLTKEGCNQAEITGKKLKDILNNKKISTIYHSNMIRAKETAQIISKYFPDAKLINDPNLNEGTPYLPDPIPKNSIFDAQKIKEDNKRINKAYETYFYQPSGDEDEYQLVICHGNVIRYFLCRALQLPLFAWLRFSSYNCGITWLVLDEEGSVILREFGSVSHLPFESVTYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLY4</accession>
    <name>A0A1J1GLY4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00113600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526252.1">
        <property type="nucleotide sequence ID" value="XM_028674154.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLY4"/>
    <dbReference type="GeneID" id="39729661"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00113600"/>
    <dbReference type="OrthoDB" id="70850at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38585">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38585:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="419"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="457" mass="55004" checksum="0F1C5D24368A4079" modified="2017-02-15" version="1">MKIFKLFLFTLILFFINLFFVKSSFKNDENFNIPLNVLFSKGNHMRKRVCNECFYKNEVNLIFHSCKAFENVKNNKINRKKIVYFIKESPRFIKKFVSMKSKSNIYEILSMKTLRIFLLNKTTLLLNGFNLLKYTYLRYNYTRSILGFFQTILLRFLVVYFIQLCSSFLLFHYFNMFSQKTQAYVLHISGSKIISRIIGFLELNLINYYINIFSEIIQILIIRMLFKQHDVCLIKTLLYNSEDYLVHTNLKNKYAILYQCAKNFVITRINKLSLFTFNYLRYFVLTNLFFKFFDGTYNKFSPSDVKMPGVYSDTKKSLEKDMKYATKKEIDILRNFCKHTGCHTCGVVCHEKFIGDHQPPIQVIKDMIEYYKDKKFKLYFLKLFKLYDTKQRLYPQCVRCSQIQSASVRCKKLKLIPHYYTIRIFHFSIIFHLFLKMILLTNWRKIIIWDGENVKPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM90</accession>
    <name>A0A1J1GM90_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Mitochondrial carrier protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00124900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526364.1">
        <property type="nucleotide sequence ID" value="XM_028674765.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM90"/>
    <dbReference type="GeneID" id="39729774"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00124900"/>
    <dbReference type="OMA" id="VEMTKHK"/>
    <dbReference type="OrthoDB" id="10253709at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005371">
        <property type="term" value="F:tricarboxylate secondary active transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015742">
        <property type="term" value="P:alpha-ketoglutarate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006843">
        <property type="term" value="P:mitochondrial citrate transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053017">
        <property type="entry name" value="Mito_Cit/Oxoglu_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46982">
        <property type="entry name" value="CITRATE/OXOGLUTARATE CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46982:SF1">
        <property type="entry name" value="CITRATE_OXOGLUTARATE CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="4">
        <location>
            <begin position="7"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="4">
        <location>
            <begin position="217"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="303" mass="34383" checksum="D2325354A1D42B65" modified="2017-02-15" version="1">MSKDLIDGSILHCLETATLGLPLEVWKTRMCIYRNENTIKSFKNIYNKGLGQFYAGFYAKLVESASKGAVLLLSKEQIINFCNNLNINKTTSGFIGGACGGICQSLVMTPCTFFITASIDKKINYKEKIVYILKNTGIKTLYKGNSAMCLRQGTNWASRQGITEWIRTKVIQKKNKKEEKKIKKIDDINNIKSVNDSSNFSLTNENIIKKKENSYNLTTFEEIICGIIGGALSVWNNPFDVIRVHMQNNANNNIKLTFFQSFTNLYKEGGILYLYKGVIPRCLLCIWQTLFMVTGVKILNKYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMA4</accession>
    <name>A0A1J1GMA4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00107800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526195.1">
        <property type="nucleotide sequence ID" value="XM_028673521.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMA4"/>
    <dbReference type="GeneID" id="39729604"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00107800"/>
    <dbReference type="OrthoDB" id="369263at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="157" mass="18356" checksum="3FE18523FAC9394A" modified="2017-02-15" version="1">MKVSLSYLATICMIFFFAIFVSVSSGRNNTNFNETENAAKAIRKLLNGEIDSIKLENGDELKIETTDENYENYERNNNYSFISNYSEENDKKDLLRKKEQSKKIENSVIEDKEDFFILDSENIKNIAKFFVLENKFDESEIELFEQSLKNIIKSLNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNE4</accession>
    <name>A0A1J1GNE4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Guanylyl cyclase beta, putative</fullName>
            <ecNumber evidence="10">4.6.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">GCbeta</name>
        <name evidence="10" type="ORF">PGAL8A_00167000</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.2" evidence="10"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526783.1">
        <property type="nucleotide sequence ID" value="XM_028669986.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730196"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00167000"/>
    <dbReference type="OMA" id="IKQHILW"/>
    <dbReference type="OrthoDB" id="6127067at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140326">
        <property type="term" value="F:ATPase-coupled intramembrane lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004383">
        <property type="term" value="F:guanylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="294"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="329"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="981"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1012"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1056"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1093"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1119"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1160"/>
            <end position="1176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1292"/>
            <end position="1313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1319"/>
            <end position="1340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1352"/>
            <end position="1370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1376"/>
            <end position="1394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1401"/>
            <end position="1417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="1454"/>
            <end position="1474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2677"/>
            <end position="2696"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2708"/>
            <end position="2728"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2749"/>
            <end position="2771"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2809"/>
            <end position="2827"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="2833"/>
            <end position="2853"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="9">
        <location>
            <begin position="1537"/>
            <end position="1689"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="9">
        <location>
            <begin position="2906"/>
            <end position="3040"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1767"/>
            <end position="1806"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2388"/>
            <end position="2407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2461"/>
            <end position="2485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1767"/>
            <end position="1787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1788"/>
            <end position="1798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="2461"/>
            <end position="2472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG93962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3123" mass="370486" checksum="E9E7A71D5487956D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNG2</accession>
    <name>A0A1J1GNG2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00169300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526807.1">
        <property type="nucleotide sequence ID" value="XM_028670013.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730220"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00169300"/>
    <dbReference type="OrthoDB" id="371701at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="459"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="180"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="462"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1474" mass="177959" checksum="317C472E7001A07A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNH3</accession>
    <name>A0A1J1GNH3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00173200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526846.1">
        <property type="nucleotide sequence ID" value="XM_028670056.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNH3"/>
    <dbReference type="GeneID" id="39730259"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00173200"/>
    <dbReference type="OMA" id="HVGQNCK"/>
    <dbReference type="OrthoDB" id="385625at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="283" mass="34130" checksum="1DA52DA80BA44CBD" modified="2017-02-15" version="1">MDEQIKFLLRNIKNNLIEKILLPKENIDVKYAINIIKIIIKKHIELNNNFLELFKKLDENLGNLNYTVFNSKITKSNNCHVLSKDEFLKKKKEEKILKDKLCNVENIIKNITTTFLDSYDNIKKIKELYLFFYMFIFKFSFDKIMFKNYIYGNNDINSNNKLTKISDNINAFISLNKISEYEFICYISKIKFLTKFYSNKDINKFIKICLYNNFNFNFLKEIKVFFFLTTIIYYIENDIKLKIKINNLIINNMYTHIINIKKYILILSYNPYISKMKKISNIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNN3</accession>
    <name>A0A1J1GNN3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Proteasome subunit alpha type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00160200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the peptidase T1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526715.1">
        <property type="nucleotide sequence ID" value="XM_028675155.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNN3"/>
    <dbReference type="GeneID" id="39730127"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00160200"/>
    <dbReference type="OMA" id="YVLNDNM"/>
    <dbReference type="OrthoDB" id="431557at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03752">
        <property type="entry name" value="proteasome_alpha_type_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000058">
        <property type="entry name" value="Proteasome subunit alpha type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050115">
        <property type="entry name" value="Proteasome_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003075">
        <property type="entry name" value="PRK03996.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11599">
        <property type="entry name" value="PROTEASOME SUBUNIT ALPHA/BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="1 2 3" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Proteasome alpha-type subunits" evidence="4">
        <location>
            <begin position="5"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="246" mass="28069" checksum="9A86851631CB3F87" modified="2017-02-15" version="1">MARRYDSRTTTFSPEGRLYQVEYALEAINNASITIGIITKEGVILGADKVFISKLIDKVNNFEKIYKIDNHIFCGVAGLNADANILINQSRLYTQRYLYNYNDIEPVSQLVVQICDIKQSYTQYGGLRPYGVSFLIAGYDMKDGYQLYHTDPSGNYSGWFATAIGTNNLTASSILKQEWKKEMTLEEGLLLALKTLAKSTDNEIPKSEKIELAYLSHKDGEVFQKYLTEKEIEELIKLYTQKYVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNS2</accession>
    <name>A0A1J1GNS2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ADP/ATP carrier protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00381000</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526927.1">
        <property type="nucleotide sequence ID" value="XM_028670146.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNS2"/>
    <dbReference type="GeneID" id="39732340"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00381000"/>
    <dbReference type="OMA" id="DTIHNCM"/>
    <dbReference type="OrthoDB" id="270584at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="122"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="243"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="310"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="16"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="116"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="337" mass="40728" checksum="48E474779BAB1726" modified="2017-02-15" version="1">MENYYLKKKKKIRYKELYITTFLTHGGSNLISKLIISPLERLVIIKQTQPVLFRNVLVQSSYTYKNIIKSIYINQGLTSFWWGYNANVLNFLSFSFFRLLFHDKIKYILSLENSKNDFVKNFFLLYASSCLAISITYPLDVAHTYMTLNHEKIKNKKLYNRSVFFFIYDQLLKKDIKNLYCGFSLCLLNFIPYLLISTKLNDLFTKYFIEFHMNRNNDELSNSEKRNHINEEYKKLFNKSPSFFYYIFLGVLTGYTAQIVTYPLETIRKKYQYYNLYEKKFPKSLMHYNYLNHKKTKHILNKISNSYKGFLMHSFKLIPEYFIFSFFFYYVKNNMPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNS6</accession>
    <name>A0A1J1GNS6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00176000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526874.1">
        <property type="nucleotide sequence ID" value="XM_028670086.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNS6"/>
    <dbReference type="GeneID" id="39730287"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00176000"/>
    <dbReference type="OMA" id="FFYISKQ"/>
    <dbReference type="OrthoDB" id="10252707at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005846">
        <property type="term" value="C:nuclear cap binding complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000339">
        <property type="term" value="F:RNA cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027159">
        <property type="entry name" value="CBP80"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12412">
        <property type="entry name" value="CAP BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12412:SF2">
        <property type="entry name" value="NUCLEAR CAP-BINDING PROTEIN SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="277"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="589"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="488"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="937"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="288"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="604"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1055" mass="126500" checksum="3001E44B0270382A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP00</accession>
    <name>A0A1J1GP00_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00172700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526841.1">
        <property type="nucleotide sequence ID" value="XM_028670050.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP00"/>
    <dbReference type="GeneID" id="39730254"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00172700"/>
    <dbReference type="OMA" id="LCNYSGM"/>
    <dbReference type="OrthoDB" id="365041at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="147" mass="17348" checksum="60E03DB770FD8B90" modified="2017-02-15" version="1">MNKLNKEKRLLLLITRVNMLINLLQSRLAYPLIYPFNTTALNNEKSLEIYLEKLKKDGNFNEQAFMKSLSFITPSIISLTKLVHILKAGYSLCNYSGVTNKLTYLDRKSNKNILNKYEKKLHLLKPQVWRLLKPNDELNTKHLKWRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP73</accession>
    <name>A0A1J1GP73_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amine oxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00078100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525901.1">
        <property type="nucleotide sequence ID" value="XM_028670255.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729306"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00078100"/>
    <dbReference type="OMA" id="SAHGEYS"/>
    <dbReference type="OrthoDB" id="5046242at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.660.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050281">
        <property type="entry name" value="Flavin_monoamine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742">
        <property type="entry name" value="FLAVIN MONOAMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742:SF410">
        <property type="entry name" value="LYSINE-SPECIFIC HISTONE DEMETHYLASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="2">
        <location>
            <begin position="1471"/>
            <end position="1538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="571"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2183"/>
            <end position="2397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2642"/>
            <end position="2667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3140"/>
            <end position="3284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="295"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="380"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="410"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="574"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2183"/>
            <end position="2396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2642"/>
            <end position="2652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="2653"/>
            <end position="2663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="3140"/>
            <end position="3152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="3153"/>
            <end position="3165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="3166"/>
            <end position="3255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="3256"/>
            <end position="3273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="3275"/>
            <end position="3284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3391" mass="402524" checksum="78CBB55B6AC373FB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP84</accession>
    <name>A0A1J1GP84_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00400700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527124.1">
        <property type="nucleotide sequence ID" value="XM_028670364.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP84"/>
    <dbReference type="GeneID" id="39732537"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00400700"/>
    <dbReference type="OMA" id="CHHSSHV"/>
    <dbReference type="OrthoDB" id="387632at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="245"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="389" mass="45503" checksum="B8D863F9040AE2BE" modified="2017-02-15" version="1">MDGNSKINNHEHTENLNDAIIQKYKIWVDLPETRNILSTSVSRSFINIPYENYKFNLRRMNTIDTADLINKQKLCELPKIVNKSINSEENINDCNETDQIKSVNGDIRKNNNCNLNEIKEDKKKYINGIKVKNQTYLKNDDTNPSFGTQFHEKGTCNPCRYEWTRGCHMGRFCRFCHHSSHVPLGTERVVPDPKILATTKVRPENILTFRKFASYATSMNSLLDANSPNHIYEDKVKTYNNSKMSSPNRNNINNANNYKNGNNYKNNSNFKKTSNYKSVNNYKSIKVYKNTNIYKNSDNYVNTNNLDNTGYLNFKYYNDTNYFNNYENLSNCYNRTKLLTNNKDNEFHKTLDTFSNNKDTLKNFKELNSFTRESALKTINSYQRIKLVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP92</accession>
    <name>A0A1J1GP92_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Immune mapped protein 2 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00382200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526939.1">
        <property type="nucleotide sequence ID" value="XM_028670159.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP92"/>
    <dbReference type="GeneID" id="39732352"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00382200"/>
    <dbReference type="OMA" id="YYECVIN"/>
    <dbReference type="OrthoDB" id="372931at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040955">
        <property type="entry name" value="IMP2_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18590">
        <property type="entry name" value="IMP2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Immune mapped protein 2 N-terminal" evidence="2">
        <location>
            <begin position="231"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="394" mass="46389" checksum="5ECC5CCC03655F82" modified="2017-02-15" version="1">MEKTSKKNVKEKKKGDKKDISSKKKPKKVNSKEKTIKSSKDNDKKNEKIHKNDSFKKNKVIEKNKNDTINVNNGRGKACFLCFCCGGNEEEKLNELIMEEERRKEEERKKIEKEDKKKREDEEKEREKERERERERLRLIEEQEKDRLILLEEKEKLRLLEEEKQKQLEEEEKQKKKDTILKKKEVKPKLFTKKRAKLNFIGAAAAPNPPPESACIGEPPQVKETSISVQEGIYLIYNHENDGQLELHYSRTGKKGKGVLAYIHSKTIPDFYFEKNMGKEVIFTEVSKKMQSVYVNDLKPYYECYIEFIKMKKIFNGILYFLPAFDEQPPPKLDIVFFNSKAKQLNFVPVEKPVEFTGDYLFVIQKGLEIFKKEINMESLFSYINSYGALLSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPA4</accession>
    <name>A0A1J1GPA4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00403100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527148.1">
        <property type="nucleotide sequence ID" value="XM_028670391.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732561"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00403100"/>
    <dbReference type="OMA" id="DAYNHND"/>
    <dbReference type="OrthoDB" id="378037at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40201:SF1">
        <property type="entry name" value="AP-3 COMPLEX SUBUNIT DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40201">
        <property type="entry name" value="OSMIOPHILIC BODY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="216"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="2232"/>
            <end position="2250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="2401"/>
            <end position="2423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="2455"/>
            <end position="2474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="2596"/>
            <end position="2616"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="2660"/>
            <end position="2681"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="2723"/>
            <end position="2741"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="848"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2793"/>
            <end position="2826"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="381"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="848"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="861"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2794"/>
            <end position="2812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2813"/>
            <end position="2826"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3212" mass="387106" checksum="94C134D759868760" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPE0</accession>
    <name>A0A1J1GPE0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-editing substrate-binding complex 6 protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00387800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526995.1">
        <property type="nucleotide sequence ID" value="XM_028670221.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPE0"/>
    <dbReference type="GeneID" id="39732408"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00387800"/>
    <dbReference type="OrthoDB" id="391211at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058917">
        <property type="entry name" value="RESC6_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26188">
        <property type="entry name" value="RESC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA-editing substrate-binding complex 6 protein" evidence="1">
        <location>
            <begin position="33"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF26188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="538" mass="64615" checksum="9C071723B8D991D7" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPF2</accession>
    <name>A0A1J1GPF2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00407900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527196.1">
        <property type="nucleotide sequence ID" value="XM_028670445.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732609"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00407900"/>
    <dbReference type="OMA" id="FYEIFTY"/>
    <dbReference type="OrthoDB" id="392635at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1233"/>
            <end position="1260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1361" mass="165328" checksum="380A8F305AEBA983" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPK6</accession>
    <name>A0A1J1GPK6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CID domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00406100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527178.1">
        <property type="nucleotide sequence ID" value="XM_028670425.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPK6"/>
    <dbReference type="GeneID" id="39732591"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00406100"/>
    <dbReference type="OMA" id="DAYTCAY"/>
    <dbReference type="OrthoDB" id="385244at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="133"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="256"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="547"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="702"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="149"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="260"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="554"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="708"/>
            <end position="722"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="837" mass="99461" checksum="C0BC880E41FFEAE8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPL9</accession>
    <name>A0A1J1GPL9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">rRNA methyltransferase 1, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00409000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527207.1">
        <property type="nucleotide sequence ID" value="XM_028670457.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPL9"/>
    <dbReference type="GeneID" id="39732620"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00409000"/>
    <dbReference type="OMA" id="QVPPYEY"/>
    <dbReference type="OrthoDB" id="270651at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016435">
        <property type="term" value="F:rRNA (guanine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047182">
        <property type="entry name" value="MRM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013123">
        <property type="entry name" value="SpoU_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46103">
        <property type="entry name" value="RRNA METHYLTRANSFERASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46103:SF1">
        <property type="entry name" value="RRNA METHYLTRANSFERASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08032">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00967">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="RNA 2-O ribose methyltransferase substrate binding" evidence="7">
        <location>
            <begin position="74"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="348" mass="41085" checksum="88BBA139F89CCC5D" modified="2017-02-15" version="1">MRKSIKYFLFLFLSSKRFKNLNIQLNSPKINNNNLKENVRKNYKLYPSSNQKNASINIKRNKFLYQNNIDDVDYVYGLNSVYSVLKKNERTIKSVIINKNIKLNRKIHKKTYEYVFNTIKERNIEIKLMDKNKMNELVGGFLHNDIIMKASYRIMKNYNYFIKNINKLIKSNIYICLHDVYDNMNIGNICRSIYFFGGNIIFLKKKKKVNEKKNQIKIDTPILHSSVGSSEYLEFFHINDMDNFMSEMKKIGFTIYSTSCLKDDTVMEKYIDLKNIKIKNNDKILIILGNESKGLSENILKNSDFCIYINSKQNRTNFDNKLSNENNNLILDSLNVSNVCSIVLHHFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ27</accession>
    <name>A0A1J1GQ27_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Elongation factor Ts, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00202000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527438.1">
        <property type="nucleotide sequence ID" value="XM_028670713.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ27"/>
    <dbReference type="GeneID" id="39730546"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00202000"/>
    <dbReference type="OMA" id="CVNILIY"/>
    <dbReference type="OrthoDB" id="374736at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070125">
        <property type="term" value="P:mitochondrial translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001816">
        <property type="entry name" value="Transl_elong_EFTs/EF1B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11741">
        <property type="entry name" value="ELONGATION FACTOR TS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11741:SF0">
        <property type="entry name" value="ELONGATION FACTOR TS, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="396" mass="47367" checksum="D4F3B37797FDE4EF" modified="2017-02-15" version="1">MFANHNKYYLRALIKKCFFSTSHSFSSKDNIKKIQEFRKLTNLSFGICKNVLNKNNYNIENSINYIFQNFRTNFENKKKELTEGYYCLKLKNNQIGLIELNCYNDLISENIFFKELLVNLCNNLIEGCTSKKISKEYWDKENIPHYLHLFYKDNKTNVDKKLENVNDTNIFKHIYFNRSINQLINYTSLILNDYIFLRKYLTLNLDNIHKENAYIIKNYYYHKELRIEDFILCKGFSFAFLFIKSKIDISENTKHILEKLSFLICVNILMYKPNYCSISYEFNIFECFKPYFNSSYTKFLGSKENKRINELSMEQLGEIDNNKQNVENTDDLMKKNVQAIHILSDCLEKGNYKTLNSLKKKNITFFELITLLEEELNIKIYTKIIYSLLNEDIIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ47</accession>
    <name>A0A1J1GQ47_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00085800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525976.1">
        <property type="nucleotide sequence ID" value="XM_028671089.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ47"/>
    <dbReference type="GeneID" id="39729382"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00085800"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="120"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="2">
        <location>
            <begin position="198"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="230" mass="27625" checksum="849931F021207430" modified="2017-02-15" version="1">MQRYLQKVLLNAFKRKTGNGFNYLSINYLNNFCTDNVNNSSKVFHMNKKCITRYWAESTNKKIHDSKINEWREQFKILADYDDKDLMIWRDSFNKMDKDKDNFISHADLQKSEWSLEKYNLFQNYDMDKNNLIDFGEYIQAVIDIDTQYFKNFFQGFSKIDIELEFQKYAITEKENNKKVIPLSKLMQMIKDKEFTCVTETDSLKLFKSMDMNKDGSIDFEDFLAWLGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ95</accession>
    <name>A0A1J1GQ95_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00091400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526032.1">
        <property type="nucleotide sequence ID" value="XM_028671710.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ95"/>
    <dbReference type="GeneID" id="39729438"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00091400"/>
    <dbReference type="OMA" id="WILTVNY"/>
    <dbReference type="OrthoDB" id="378325at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="365"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="135"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="304"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="365"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="387"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="756" mass="91478" checksum="D43EED4B79864D4B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQI5</accession>
    <name>A0A1J1GQI5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Rhoptry neck protein 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">RON2</name>
        <name evidence="4" type="ORF">PGAL8A_00211200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527530.1">
        <property type="nucleotide sequence ID" value="XM_028670815.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730639"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00211200"/>
    <dbReference type="OMA" id="QAPYFGH"/>
    <dbReference type="OrthoDB" id="345453at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012543174" evidence="3">
        <location>
            <begin position="21"/>
            <end position="1937"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1817"/>
            <end position="1843"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="640"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1390"/>
            <end position="1425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="370"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="397"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="448"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="462"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="493"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="514"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="531"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="561"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="640"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1410"/>
            <end position="1425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1937" mass="222764" checksum="FA03C0EF2447CA04" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQN4</accession>
    <name>A0A1J1GQN4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Vacuolar protein sorting-associated protein 4, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">VPS4</name>
        <name evidence="6" type="ORF">PGAL8A_00216800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527586.1">
        <property type="nucleotide sequence ID" value="XM_028670878.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQN4"/>
    <dbReference type="GeneID" id="39730695"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00216800"/>
    <dbReference type="OMA" id="IEWTNEF"/>
    <dbReference type="OrthoDB" id="29072at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007033">
        <property type="term" value="P:vacuole organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02656">
        <property type="entry name" value="MIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000126">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001003">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.80">
        <property type="entry name" value="Phosphotransferase system, lactose/cellobiose-type IIA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007330">
        <property type="entry name" value="MIT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036181">
        <property type="entry name" value="MIT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050304">
        <property type="entry name" value="MT-severing_AAA_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015415">
        <property type="entry name" value="Spast_Vps4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074">
        <property type="entry name" value="AAA DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074:SF83">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04212">
        <property type="entry name" value="MIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09336">
        <property type="entry name" value="Vps4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00745">
        <property type="entry name" value="MIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116846">
        <property type="entry name" value="MIT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MIT" evidence="5">
        <location>
            <begin position="3"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="146"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG94771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="419" mass="48392" checksum="63FDFA8F6F8A5C53" modified="2017-02-15" version="1">MDSEETINLAVKYAKDAVIEDEKKNYKEALNLYIQSLQYFHFFCKYEKNANIRELILKKMEIYMARAESLKKIINKKEVIETKEKVGNSEETKENMKKQVKEFIMNKNNNVKWSDVCGLELAKEVLKEAIIFPLKFPKLFNSSSLPYKGILLYGPPGTGKTFLALACANECSMNFFNVSSSDLISKYQGESEKYIKCLFETAKENSPSIIFIDEIDSLCGSRTDGENESTRRIKTEFLINMSGLQNYENNIIVMGATNTPWSLDSGFRRRFEKRIYIPLPNLYARMKIFEKYIKNSESSDIQKEDIKYFATLTENYTGADIDIICRDAVYMPIKKCLLSKFFKKVNKNNKIYYTPCSPGDTDKTKVEKNVMNINENELLLPTLSVQDFKTAITNAKPSLSLDDLKRYEEWTKQYGMSGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQN9</accession>
    <name>A0A1J1GQN9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00225000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527668.1">
        <property type="nucleotide sequence ID" value="XM_028670968.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQN9"/>
    <dbReference type="GeneID" id="39730777"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00225000"/>
    <dbReference type="OMA" id="NKYRIRC"/>
    <dbReference type="OrthoDB" id="371117at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="205"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="494" mass="58004" checksum="5D9E190A778267CD" modified="2017-02-15" version="1">MIRKRKSKIAEDEHLEENEEIMEGNFLFNKKNSTMKSIEEVVDENMEGENIEFKPMEELEKHKDSNKSIENNKEIKSNDNIESIKDNVNVKNDLELEHTYSTNIPDVNILENNTNEKHEINEVKFKAIDDLYNKYDKEVQSLLESFELLNFSELFKNPFDPTITRDEKIVRIFYFSGFSFLPYLGWVVASIYGSFCKEKNNKNIISLRIISSIQCAIFGLIIILIIALINLNGQNVLQCRNEGISFKKKLVNDAKYNVVFFGPMSTDDWMKSKLLKITEELKFNIYTISYPNLKHHTIKTKRHVFLKDALACARLKYSDVILFSFQIESAFNFTIPFLEKNEILGFFSFSKKFQKKIPTKENIGKENIIYLAPKEKNVYDIYSSITMRLCHDKNNNYYNILYIVHHSFNKYQIRCSKNLAEDYSIAVNNFNFNAIGTEEKASKYEDDDFKEVIDDFYQYLVFIRDVISQNNLEFYRKMLCNNVMCESKGAICVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQV1</accession>
    <name>A0A1J1GQV1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00206300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527481.1">
        <property type="nucleotide sequence ID" value="XM_028670761.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQV1"/>
    <dbReference type="GeneID" id="39730590"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00206300"/>
    <dbReference type="OMA" id="PRKLTTC"/>
    <dbReference type="OrthoDB" id="392654at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="121" mass="14478" checksum="3E86C9D2F2B549EE" modified="2017-02-15" version="1">MAIKNKRIKKKKSQINGILKKKKVNFINEKENDLSDNPFMQKEEIKPFNLKIEHEASEDEVQIDKFKELLKRRIKQINKIVEKNKKNFETNKMYGDDIEKSGKSWYEDKLVNDVPRKLTII</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQZ5</accession>
    <name>A0A1J1GQZ5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Conserved oligomeric Golgi complex subunit 6</fullName>
            <shortName evidence="9">COG complex subunit 6</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Component of oligomeric Golgi complex 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00224500</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Required for normal Golgi function.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the conserved oligomeric Golgi complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Golgi apparatus membrane</location>
            <topology evidence="1 9">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the COG6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527663.1">
        <property type="nucleotide sequence ID" value="XM_028670962.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQZ5"/>
    <dbReference type="GeneID" id="39730772"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00224500"/>
    <dbReference type="OrthoDB" id="382797at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010490">
        <property type="entry name" value="COG6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048369">
        <property type="entry name" value="COG6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048368">
        <property type="entry name" value="COG6_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21506">
        <property type="entry name" value="COMPONENT OF OLIGOMERIC GOLGI COMPLEX 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21506:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20653">
        <property type="entry name" value="COG6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06419">
        <property type="entry name" value="COG6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Conserved oligomeric complex COG6 N-terminal" evidence="10">
        <location>
            <begin position="65"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="Conserved Oligomeric Golgi complex subunit 6 C-terminal" evidence="11">
        <location>
            <begin position="634"/>
            <end position="819"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF06419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF20653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG94848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="828" mass="99569" checksum="3307DF90EED5B68C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRL0</accession>
    <name>A0A1J1GRL0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00250300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527914.1">
        <property type="nucleotide sequence ID" value="XM_028671242.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRL0"/>
    <dbReference type="GeneID" id="39731031"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00250300"/>
    <dbReference type="OMA" id="NMDTQTG"/>
    <dbReference type="OrthoDB" id="366397at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="73"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="113"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="292" mass="33738" checksum="FD7B6AA8D69694BF" modified="2017-02-15" version="1">MALLNIKNNANISLHSMRYSDLQLDYDSDSSSNEESPFFSVDDFSNELHSSFDDISDYIVVDESDLKRERSENTSSENNETTSTKDIEMKKDENVKNEKKYKNANYSEESKNCSDNNNDNKNNNNSDNNNDVNNNSTNGNNKKQCFSRTLGTEGRKRMLKLLRKAYKYNEECKLIMKNKNPPLSISYLPYFNLSMLWQLAEDFGVFNEALKIHRECIKKRNSNVRFRANGKASGNYNFQELNKNTKSSKSEYMSDYVGSNMDTQTGEDCEMANNNILNDDIQGKRKRKKSNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRS0</accession>
    <name>A0A1J1GRS0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Kinetochore protein SPC25</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">SPC25</name>
        <name evidence="11" type="ORF">PGAL8A_00257000</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the NDC80 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
            <location evidence="1">Centromere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Chromosome</location>
            <location evidence="9">Centromere</location>
            <location evidence="9">Kinetochore</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the SPC25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527978.1">
        <property type="nucleotide sequence ID" value="XM_028671314.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRS0"/>
    <dbReference type="GeneID" id="39731098"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00257000"/>
    <dbReference type="OMA" id="GDPQKKY"/>
    <dbReference type="OrthoDB" id="4056921at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031262">
        <property type="term" value="C:Ndc80 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd23784">
        <property type="entry name" value="RWD_Spc25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.457.50">
        <property type="entry name" value="Chromosome segregation protein Spc25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045143">
        <property type="entry name" value="Spc25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013255">
        <property type="entry name" value="Spc25_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14281:SF0">
        <property type="entry name" value="KINETOCHORE PROTEIN SPC25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14281">
        <property type="entry name" value="KINETOCHORE PROTEIN SPC25-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08234">
        <property type="entry name" value="Spindle_Spc25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="8 9" id="KW-0137">Centromere</keyword>
    <keyword evidence="3 9" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="5 9" id="KW-0498">Mitosis</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromosome segregation protein Spc25 C-terminal" evidence="10">
        <location>
            <begin position="145"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG95165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="216" mass="25639" checksum="A779703AABBD90AA" modified="2017-02-15" version="1">MENMLDNNEIKNSLQQQLNQIVGDQEKQYNEIKSYIENEKKQIEIMKNKTKEKKMSINRINHEIEANTVLVAELKESVLEEEKKLEEYPKLIDEINNKLNLILKNFDSSKLEYKTVKLHKDYIQNEWKKKLETLYNLLGFEIILEDDKILIEFSNIQESEPHKKYRATVALNNGSYEAVDTTPRINNFEDFVDNLNKGLPFTTFCCLLRRSFKELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRX0</accession>
    <name>A0A1J1GRX0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Nucleoside transporter 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">NT1</name>
        <name evidence="8" type="ORF">PGAL8A_00258300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527991.1">
        <property type="nucleotide sequence ID" value="XM_028671328.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRX0"/>
    <dbReference type="GeneID" id="39731111"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00258300"/>
    <dbReference type="OMA" id="MGIWTTY"/>
    <dbReference type="OrthoDB" id="46396at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005337">
        <property type="term" value="F:nucleoside transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002259">
        <property type="entry name" value="Eqnu_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10332">
        <property type="entry name" value="EQUILIBRATIVE NUCLEOSIDE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10332:SF10">
        <property type="entry name" value="EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01733">
        <property type="entry name" value="Nucleoside_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="37"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="274"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="304"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="340"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="378"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="412" mass="46696" checksum="99D1A6EF0C762888" modified="2017-02-15" version="1">MSTGKDSSKVSADIEMKEVYVDENKKSSKITSTNKRTLNILTFILIGLSSLNVWNTALGLNINLKYNTFQITGLVCSSIVALFIDIPKFLLPYFLGGLAILSAGFQITHQLLTENQFSIYCLITFVIIGIMAGLAQTIAFNIASTMEENMGGYMSTGIGISGVFIFVINLLLDQFVSSEKKYGINKEKLLYLYFICEICLVLAILLCVFNLELSKKKVKKDDEEISERSLSYMELIKDSYKAIISIFFVNMLTLQLFPGVGHKKWAKSHDISDYNVTIIVGMFQVFDFISRYPPNLSHIKYFKIFTFSLNKLLIANAIRIIFIPWFILNSCLKNSFFSNIVQHCFCMALFAFTNGWFNTVPFLVFVNELKVAKKPKDIETVSTFMVIAMFLGLCAGIWSTYIYDLFPIVIKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS45</accession>
    <name>A0A1J1GS45_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">SRPK1</name>
        <name evidence="13" type="ORF">PGAL8A_00001700</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528063.1">
        <property type="nucleotide sequence ID" value="XM_028671407.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728539"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00001700"/>
    <dbReference type="OrthoDB" id="2649at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050684">
        <property type="term" value="P:regulation of mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000797">
        <property type="entry name" value="CMGC/SRPK protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051334">
        <property type="entry name" value="SRPK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47634:SF9">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 13" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="54"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1031"/>
            <end position="1147"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="257"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="1205"/>
            <end position="1253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1031"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1045"/>
            <end position="1116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1117"/>
            <end position="1133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1135"/>
            <end position="1147"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG95252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1353" mass="160241" checksum="7FCB1F8CABB98DEC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS94</accession>
    <name>A0A1J1GS94_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00255500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527963.1">
        <property type="nucleotide sequence ID" value="XM_028671296.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS94"/>
    <dbReference type="GeneID" id="39731083"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00255500"/>
    <dbReference type="OMA" id="PLMINCK"/>
    <dbReference type="OrthoDB" id="381984at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="491" mass="57600" checksum="F18B24A622B481C6" modified="2017-02-15" version="1">MNKKDENENILNCKNFKRSFENFNNLDSQNSMYMFAFHKRRHNLDLKDEVKNNYENIEIISGLNRKNKRKLEANFIDKNKKRNFTETQKNFNFSNDAFSNNSSSGVSNIVIDEINDKCIKNSSRNNDRLLSESKIDENKKHSFELAIIPFEGNTSVSDYKYENNITLKNSNLKNIFSFLSKKDIFYKNLKNHIKKNKPLMINCKDFNILLNKYKYENEIGKKIDENHNTLDNNDNYEIENNLINNSLVMNNTIIEPTDLNDLSKNENNFCLKNNDLLNTKLNEMYLDSPINECDINYALNNNNMNDINNVKKGDKFDNLSKAFNTNNIDSSHNNFGEIKNPNEVNYMNNNYNFSNINISNNDINVNNYNLNDNNILNNLNNISFNKINDNSLRFNNNVNFNVLNNQNNFSNLNNDSNLSNNNFNNLNVIDNYDNLNNNYNMFNLSNFNYNDDSNSNENIYYLNNINNINKLLNLNNAYIQNNINNFNNINK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSH5</accession>
    <name>A0A1J1GSH5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Exosome complex component RRP45, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">RRP45</name>
        <name evidence="9" type="ORF">PGAL8A_00171000</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNase PH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526824.1">
        <property type="nucleotide sequence ID" value="XM_028670031.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSH5"/>
    <dbReference type="GeneID" id="39730237"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00171000"/>
    <dbReference type="OMA" id="FFWCNLK"/>
    <dbReference type="OrthoDB" id="10264038at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035925">
        <property type="term" value="F:mRNA 3'-UTR AU-rich region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071028">
        <property type="term" value="P:nuclear mRNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034473">
        <property type="term" value="P:U1 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034476">
        <property type="term" value="P:U5 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11368">
        <property type="entry name" value="RNase_PH_RRP45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050590">
        <property type="entry name" value="Exosome_comp_Rrp42_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033100">
        <property type="entry name" value="Rrp45"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097:SF14">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11097">
        <property type="entry name" value="EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="7">
        <location>
            <begin position="39"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Exoribonuclease phosphorolytic" evidence="8">
        <location>
            <begin position="185"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="496" mass="58014" checksum="FA0D456ED6F144E8" modified="2017-02-15" version="1">MKSCKNNANFFWCNLKNNLRLDGRNFEDSRNISFYFLGDYGNVEVSIGFTKVICRITSEIVKPFDKKPNEGIIKINLDIDSFTSVNDNLKINDECLEIRNLIERILKSSSILNFESLCIIPHKKVWCLLINIIVIENDGNLFDACYLSAYSALVHFRNNEVKVENSEIIIDQDESNYSPLSIHNSPILTTFAYFNSEDICLIDPSLHEEEFMSSKLSVALNKNGQLISILKPGGSPISYLKILEAIELAKKRVTCILKILEDALEEDKKLRDDLKKKNFHIKYSCNPVSIKYNDSYEKSMNIPVNQSLRNNWNIEKIIKKYEQYIKLQDMEQEENLVSSIEETNNNENTKYNKQYILNEELRKIKNENKIKHENYLYVDNYNDYMSNIKDNNFLEEPFKNKNILDNLDIGKIKRQEFGDNNSYLHNNKFLKTNDIQKKEIMNFSNTITKNIKEKKNINKENKTESMTTNKEYSSDIDFSIAINESLKKKKKKKKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSM3</accession>
    <name>A0A1J1GSM3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00272500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000043">
        <property type="protein sequence ID" value="CRG95525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528334.1">
        <property type="nucleotide sequence ID" value="XM_028671708.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSM3"/>
    <dbReference type="GeneID" id="39731257"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00272500"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="138" mass="16090" checksum="3C3C64C3CB91CCE4" modified="2017-02-15" version="1">MRQLLTTINTTIASYTSANFNVSESNNNNNNNSNSVDSIYLVILALILSIKLFFMFYTIIYTYRRRGRAIYDDLMLEVESVDSGYADIEYEDIDEEIDERARILDVDDRAERTVNERVTLNVYGQINSEEDEVEVRIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GT47</accession>
    <name>A0A1J1GT47_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DnaJ protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00285500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528466.1">
        <property type="nucleotide sequence ID" value="XM_028671855.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GT47"/>
    <dbReference type="GeneID" id="39731388"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00285500"/>
    <dbReference type="OrthoDB" id="10250354at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051787">
        <property type="term" value="F:misfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051948">
        <property type="entry name" value="Hsp70_co-chaperone_J-domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44360">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44360:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="209"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="362"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="55"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="381" mass="45645" checksum="97900BE3B3BBDD2C" modified="2017-02-15" version="1">MEEIIMHMIIIAPLTKWLIGSNRVWNKGKREYGIYLALLLLFCVGIYELRKPDKNFYEILNLNSYASKGDIQQSFRRMSRIYHPDKNKESDSLDRFNKIREAYEVLANEEKKYYYDRYGDFGESEITNFFYVEILIISIFQFAISFIFGFLYTYGKDNEKYRILICLYITLNFCMEIIYRFSQESNSFLSFLPIFCHYTPFERIQALRVLVPLVMNAILLLDIYFLDEDTEVYISSFCEYVFENNSKIIKNLEDTVIFYARLIDGKIDENNDFSWRKEKTNIQIKNVYELDEELTYDKKYDKDDLFYSLLYKIIENNKDQIDLKIPKKELCRRFDWSRWFIASVFEINAEEKNFIESNATKGIIFSSALYFIGLASHLLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTQ3</accession>
    <name>A0A1J1GTQ3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Kelch protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00181900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527248.1">
        <property type="nucleotide sequence ID" value="XM_028670502.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTQ3"/>
    <dbReference type="GeneID" id="39730346"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00181900"/>
    <dbReference type="OMA" id="KWIMGKP"/>
    <dbReference type="OrthoDB" id="45365at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052392">
        <property type="entry name" value="Kelch-BTB_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46375:SF3">
        <property type="entry name" value="KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46375">
        <property type="entry name" value="KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 13-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="392" mass="44752" checksum="DA50153653AEE520" modified="2017-02-15" version="1">MDVLNKDFSSACLNRDDYLNNENDVINIDKKKIINHDIFNNISSSNKANNVSNNKNHVNKTQIINRDNKTNNINDTHNKIHYNEINNFCNTKEELKKTNNEVEIVYSYVINDSKNINSNNELITIDISFDEDKKYIFRKTIKKLPFFRYGHFLCLTKNGCVLAIGGTDGKKKYGIVEKYCQEKKKWKQINIMHFSRSNFCGVCTDNNDLFILGGEGDQSILKSVEYFDSKINAWRSLPPLNCVRHSASAIIFQNFLFIIGGKDGIGDYGKVHKSVEMLNLNEKNMKWVMCNPLKQARLGLATIVFKNKIYAIGGSTGVKNLSSVEIYDLNTNSWIEGPNLNFARSNLVAFTWKNHLVVYGGINKQKGDLINSAEILNEKTSCWILLNENDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTQ5</accession>
    <name>A0A1J1GTQ5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Translocon component PTEX150, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">PTEX150</name>
        <name evidence="4" type="ORF">PGAL8A_00307800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528674.1">
        <property type="nucleotide sequence ID" value="XM_028672085.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTQ5"/>
    <dbReference type="GeneID" id="39731611"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00307800"/>
    <dbReference type="OMA" id="YVFTSVY"/>
    <dbReference type="OrthoDB" id="372932at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013085590" evidence="3">
        <location>
            <begin position="23"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="32"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="214"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="384"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="476"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="858"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="534"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="44"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="214"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="232"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="257"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="482"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="498"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="882"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="897"/>
            <end position="908"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="980" mass="113920" checksum="EB8FBB3BFA49B39E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTR2</accession>
    <name>A0A1J1GTR2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WIBG Mago-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00313100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528726.1">
        <property type="nucleotide sequence ID" value="XM_028672144.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTR2"/>
    <dbReference type="GeneID" id="39731664"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00313100"/>
    <dbReference type="OMA" id="GWNPVNE"/>
    <dbReference type="OrthoDB" id="21625at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035145">
        <property type="term" value="C:exon-exon junction complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903259">
        <property type="term" value="P:exon-exon junction complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039333">
        <property type="entry name" value="PYM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015362">
        <property type="entry name" value="WIBG_mago-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036348">
        <property type="entry name" value="WIBG_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22959:SF0">
        <property type="entry name" value="PARTNER OF Y14 AND MAGO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22959">
        <property type="entry name" value="PYM PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09282">
        <property type="entry name" value="Mago-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01273">
        <property type="entry name" value="Mago-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101931">
        <property type="entry name" value="Pym (Within the bgcn gene intron protein, WIBG), N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WIBG Mago-binding" evidence="2">
        <location>
            <begin position="47"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="135" mass="15957" checksum="96630C825D41037B" modified="2017-02-15" version="1" fragment="single">MNSQNFLESKFNNISYNTYEKDKNLEDYMKEVVTPLGDTYIINEKTNEKFIKATQRSDGTFRKTIRVRSDYMPQEENCVYKVKGKLLEEQNKIINTSKNLNTNTKVENTKKIPGWNPVNEHENTTNIKKKKKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTW6</accession>
    <name>A0A1J1GTW6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00188100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000026">
        <property type="protein sequence ID" value="CRG94486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527304.1">
        <property type="nucleotide sequence ID" value="XM_028670564.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTW6"/>
    <dbReference type="GeneID" id="39730408"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00188100"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="134" mass="15343" checksum="CE4ED44B948A73C1" modified="2017-02-15" version="1">MEPEKNHNPFSTLGDEHNKNSYVTIHLNDQDNCAVNFTNLCTPNNNEIPIQQNVISNNSPEKGVYIRNNGARDYIESFSCGIAFCSALLFFAIRHLFLGCYRGLRRLKRERFDNNNGNSEQKSLTSNVNNEQEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTX0</accession>
    <name>A0A1J1GTX0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RAP protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00215500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527573.1">
        <property type="nucleotide sequence ID" value="XM_028670862.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTX0"/>
    <dbReference type="GeneID" id="39730682"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00215500"/>
    <dbReference type="OMA" id="IWAGYYN"/>
    <dbReference type="OrthoDB" id="411182at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="876" mass="105508" checksum="A8F9E5D9EA00F8B9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU37</accession>
    <name>A0A1J1GU37_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00296700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528563.1">
        <property type="nucleotide sequence ID" value="XM_028671962.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU37"/>
    <dbReference type="GeneID" id="39731500"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00296700"/>
    <dbReference type="OMA" id="FHKKKMK"/>
    <dbReference type="OrthoDB" id="392389at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="63"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="308" mass="36743" checksum="74EFD2CF86FAA625" modified="2017-02-15" version="1">MDQKHNENLNDKEIQSFFNEIDNIFNEEDNNNFVKLEEELNEKCFQLIKKKENSHNLSIQSKLNLFIEEIEFINNVLDTYEKEKKKNENKNENLLKKDGYNESEDILNDLIYLELGLRDSDNTNETKKLLLKISENLYKIKSKEFILTMKKSLDIRINDFRKNEISEEYFSKKINEIYIDTKNQLDYEIDEKEKKSKENIIENSKNILIDSDTTNNLVDMNLDGNLIPLVPMDKCVNKIDKSEIDTKNENDQIKEAKISNKMINIKKNRKEQKIESSNFFHKKKLKLVERWNRVAEETKLLNDYDSSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUF2</accession>
    <name>A0A1J1GUF2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pescadillo homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">PES</name>
        <name evidence="7" type="ORF">PGAL8A_00335000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
            <location evidence="4">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
            <location evidence="4">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the pescadillo family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528940.1">
        <property type="nucleotide sequence ID" value="XM_028672382.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUF2"/>
    <dbReference type="GeneID" id="39731880"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00335000"/>
    <dbReference type="OMA" id="QKVTWIV"/>
    <dbReference type="OrthoDB" id="10264910at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070545">
        <property type="term" value="C:PeBoW complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043021">
        <property type="term" value="F:ribonucleoprotein complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000466">
        <property type="term" value="P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03028">
        <property type="entry name" value="Pescadillo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010613">
        <property type="entry name" value="PES"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12221">
        <property type="entry name" value="PESCADILLO - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12221:SF6">
        <property type="entry name" value="PESCADILLO HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16589">
        <property type="entry name" value="BRCT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06732">
        <property type="entry name" value="Pescadillo_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="2 4" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="BRCT" evidence="6">
        <location>
            <begin position="385"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="323"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="563"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="327"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="630" mass="75858" checksum="895B34AA005554FA" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVE4</accession>
    <name>A0A1J1GVE4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00348600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529073.1">
        <property type="nucleotide sequence ID" value="XM_028672529.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVE4"/>
    <dbReference type="GeneID" id="39732016"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00348600"/>
    <dbReference type="OMA" id="IMKSYAI"/>
    <dbReference type="OrthoDB" id="436833at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="480" mass="57322" checksum="16FFA6CF8E325215" modified="2017-02-15" version="1">MMNFSLLIKRYSKILNWKHDTYYASLMNKYVYFEEFMRFCNDNKEGFSKRDIIASLTYISHMKKVDLLSPTFNSYNNFIFSNINIFRSNISTLVHRYAILGHTKSLLFIYENVLKNNILNYDNKTISLIAWSYAKNSFYLADLFMEINKILHGCIKTMNLHELSLISWAYSKINRLPPLELICVKNRVYHLLNLLDEESNSELKKGTIKENIGIIKMDLNENITNYEKQKNNENYFHIKNLNSYNNNFKQYDQNKELEPQNQSLENIYEENNENKIDLYGCKKNLSQDICMIMKSYAIMNKTDPFFFFFLFNFMIKNIRNNKIMITAQGITSIWVCLREYEIKNKRIIEYALELSRFLRLDHTVNSSMMHEIITSIYKLKIKDRRILYHLFYHLKRKCVNMHIQHLYDIIIYLQEMNIHDDDLWKQFGVAIQKKAIDLELLQIKNLHNIFTINGKGNDRILGVLDTFIQIKEDVNAYGPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVF0</accession>
    <name>A0A1J1GVF0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00365900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529239.1">
        <property type="nucleotide sequence ID" value="XM_028672714.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVF0"/>
    <dbReference type="GeneID" id="39732189"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00365900"/>
    <dbReference type="OMA" id="REWGTEN"/>
    <dbReference type="OrthoDB" id="365936at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="185" mass="20539" checksum="51CC91F8643F9C13" modified="2017-02-15" version="1">MKIFNYICGRPLSGGAAPLIYNPVRKWLIILMMLYICLSILSYGIFLFPKASDLQCSALINSLFNFSLSIGVSNIMAPYFSIISCREWGTEHEWALVALVSAVMAIIDVSSSCYGIYVLYTIIDVIFVNISGIHGDCNSYKAVLFFSANSFLVVLHLIVAIVCTVVFFLLMAGIDKQLHDIRNTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVF8</accession>
    <name>A0A1J1GVF8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Inner membrane complex protein 1b, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">IMC1b</name>
        <name evidence="2" type="ORF">PGAL8A_00369400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529274.1">
        <property type="nucleotide sequence ID" value="XM_028672752.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVF8"/>
    <dbReference type="GeneID" id="39732224"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00369400"/>
    <dbReference type="OMA" id="HPLEMVH"/>
    <dbReference type="OrthoDB" id="390870at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022086">
        <property type="entry name" value="IMCp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12314">
        <property type="entry name" value="IMCp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="512" mass="60316" checksum="9A566B499E9E5353" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVL7</accession>
    <name>A0A1J1GVL7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">U3 snoRNA-associated small subunit rRNA processing associated protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00245800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527872.1">
        <property type="nucleotide sequence ID" value="XM_028671195.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVL7"/>
    <dbReference type="GeneID" id="39730986"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00245800"/>
    <dbReference type="OMA" id="SIMWISK"/>
    <dbReference type="OrthoDB" id="8883818at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034455">
        <property type="term" value="C:t-UTP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046351">
        <property type="entry name" value="UTP4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44163">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44163:SF1">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1064" mass="126881" checksum="CBDFCEE63CB93293" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW59</accession>
    <name>A0A1J1GW59_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA-directed RNA polymerase II subunit RPB3, putative</fullName>
            <ecNumber evidence="5">2.7.7.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPB3</name>
        <name evidence="5" type="ORF">PGAL8A_00435900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529580.1">
        <property type="nucleotide sequence ID" value="XM_028673093.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW59"/>
    <dbReference type="GeneID" id="39732891"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00435900"/>
    <dbReference type="OMA" id="DETKFHF"/>
    <dbReference type="OrthoDB" id="270173at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006366">
        <property type="term" value="P:transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.12">
        <property type="entry name" value="DNA-directed RNA polymerase, insert domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="entry name" value="RNA polymerase, RBP11-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00320">
        <property type="entry name" value="RNApol_arch_Rpo3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001514">
        <property type="entry name" value="DNA-dir_RNA_pol_30-40kDasu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011262">
        <property type="entry name" value="DNA-dir_RNA_pol_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011263">
        <property type="entry name" value="DNA-dir_RNA_pol_RpoA/D/Rpb3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022842">
        <property type="entry name" value="RNAP_Rpo3/Rpb3/RPAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036643">
        <property type="entry name" value="RNApol_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050518">
        <property type="entry name" value="Rpo3/RPB3_RNA_Pol_subunit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001988">
        <property type="entry name" value="PRK00783.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11800">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11800:SF2">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01000">
        <property type="entry name" value="RNA_pol_A_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01193">
        <property type="entry name" value="RNA_pol_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00662">
        <property type="entry name" value="RPOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56553">
        <property type="entry name" value="Insert subdomain of RNA polymerase alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="RBP11-like subunits of RNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00446">
        <property type="entry name" value="RNA_POL_D_30KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase RpoA/D/Rpb3-type" evidence="4">
        <location>
            <begin position="22"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="329" mass="37785" checksum="B8F503E5947821B1" modified="2017-02-15" version="1">MIASNDISNKHKIEITKLTKDEMSFILYNSNSGLANALRRIILSEIPTLAIDVVNVYENTSPFHDEYLAHRLGLIPIDSRNVNNYEFREKCKCKETCSKCTIQYVIEVKCNNANKIDISHYDIESLDHEPNIPMPIPHGKKNTKRENAIPIVTLSKNQTLHMKLIATKGIGKMHAKWIPANVSYRIDHKIKIKHHLIDKLPQSHKLMLANNLNKDCYVLKNIDEDRDVQLKLNENMSVVMAENCIEILNELGYKDVIKIIYDDTKFHFHIESVGSLPPEQIVEMALEVLENKLKNLEPQIKSSFYSIDEVAKQLKEQGVSLYGIQLDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWH9</accession>
    <name>A0A1J1GWH9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alpha-tubulin N-acetyltransferase</fullName>
            <shortName evidence="3">Alpha-TAT</shortName>
            <shortName evidence="3">TAT</shortName>
            <ecNumber evidence="3">2.3.1.108</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Acetyltransferase mec-17 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00437700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>L-lysyl-[alpha-tubulin] + acetyl-CoA = N(6)-acetyl-L-lysyl-[alpha-tubulin] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15277"/>
            <dbReference type="Rhea" id="RHEA-COMP:11278"/>
            <dbReference type="Rhea" id="RHEA-COMP:11279"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="EC" id="2.3.1.108"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the acetyltransferase ATAT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.108" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529599.1">
        <property type="nucleotide sequence ID" value="XM_028673114.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWH9"/>
    <dbReference type="GeneID" id="39732910"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00437700"/>
    <dbReference type="OMA" id="IKQPNNF"/>
    <dbReference type="OrthoDB" id="447510at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019799">
        <property type="term" value="F:tubulin N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070507">
        <property type="term" value="P:regulation of microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03130">
        <property type="entry name" value="mec17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038746">
        <property type="entry name" value="Atat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007965">
        <property type="entry name" value="GNAT_ATAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12327">
        <property type="entry name" value="ALPHA-TUBULIN N-ACETYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12327:SF0">
        <property type="entry name" value="ALPHA-TUBULIN N-ACETYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05301">
        <property type="entry name" value="Acetyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51730">
        <property type="entry name" value="GNAT_ATAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="4">
        <location>
            <begin position="1"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="113"/>
            <end position="126"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="149"/>
            <end position="158"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="site" description="Crucial for catalytic activity" evidence="3">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="204" mass="24284" checksum="B89B72242F67AA6A" modified="2017-02-15" version="1">MKYILNDISNEKLKKLDIKKYTKNDLLYLRDYSSFSFQKLEKEIEEIGRLSSEDQKLYGTLTSINNIIDQNYTLYCLIIENNLIGILKIGSKNLYLYDKKNLHYQRCTCVLDFYILNNFQKMGLGIKLFNFMLKDNNIAPSKLCYDNPSKKLQNFLKKYFSPCNLIKQPNNFVIFSEYFDSSLEYFNRNYANIENRNENTMRCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWJ0</accession>
    <name>A0A1J1GWJ0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00442000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529642.1">
        <property type="nucleotide sequence ID" value="XM_028673161.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWJ0"/>
    <dbReference type="GeneID" id="39732953"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00442000"/>
    <dbReference type="OMA" id="KNSCDNA"/>
    <dbReference type="OrthoDB" id="5382468at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="47"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="203"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="280" mass="32603" checksum="CFAB13909713821C" modified="2017-02-15" version="1">MSIKSKIDMSLDELIEKENIKVNLKSSNEKKTVNKFIEKNTGQKYLHSIIISNVNSKNLELYKKEFSKFGKIYNIFHDNDKKITYVKYDNKNSCDNAISTMNNKTLDGDTITIVLGKKILDKKNGKNMNQNNNIINNNINNNKIIPPYKVPIYNPNTYPYYVNNYTPYNNMPYPNTYQNNFFEKNITPYNNNNKNIYETHKNNTIIVTNVPTYLNAEDIFSAFQETGKIVDVQILMNEKRKLTGIVSIEYEKNEAASDAVRMYDGGFLNDNRIRVFLDCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWL4</accession>
    <name>A0A1J1GWL4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00444400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529666.1">
        <property type="nucleotide sequence ID" value="XM_028673188.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWL4"/>
    <dbReference type="GeneID" id="39732977"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00444400"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012046042" evidence="2">
        <location>
            <begin position="21"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="463"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="463"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="480"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="605" mass="68571" checksum="004CBBF6DBA272A0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWN3</accession>
    <name>A0A1J1GWN3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Zinc finger protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00292100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528525.1">
        <property type="nucleotide sequence ID" value="XM_028671920.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWN3"/>
    <dbReference type="GeneID" id="39731454"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00292100"/>
    <dbReference type="OrthoDB" id="512667at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050821">
        <property type="term" value="P:protein stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024158">
        <property type="entry name" value="Mt_import_TIM15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007853">
        <property type="entry name" value="Znf_DNL-typ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20922">
        <property type="entry name" value="DNL-TYPE ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20922:SF13">
        <property type="entry name" value="DNL-TYPE ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05180">
        <property type="entry name" value="zf-DNL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51501">
        <property type="entry name" value="ZF_DNL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNL-type" evidence="6">
        <location>
            <begin position="158"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="138"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="248" mass="28932" checksum="A13D746B1AE9AD03" modified="2017-02-15" version="1">MTEYLLKKIFEKTLISGISVSKNKFKQKYIFYSTLKNRYNCFNSKNVLSNNNIVKINSCNSLIFFKKEFTTKNEKENKNAKETSNNKIININNIEIEGKKLNNKEGETFVYQSDKEINLTKTCHNNEKSTNESLIEVNEEKNKKKENEGSSELAEEKKNKEYLVLMFTCKICEKKSAKKFSKQAYYNGVVIIRCPSCDNLHLISDQLGWFQDGKTNIEKILEEKGEKVIKKFSYNNLLEIDDLLNAYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWU1</accession>
    <name>A0A1J1GWU1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00448900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529711.1">
        <property type="nucleotide sequence ID" value="XM_028673238.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWU1"/>
    <dbReference type="GeneID" id="39733022"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00448900"/>
    <dbReference type="OMA" id="DSNCMER"/>
    <dbReference type="OrthoDB" id="10582022at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="403" mass="47151" checksum="9F399F99DB88C73C" modified="2017-02-15" version="1">MNFSKTFSFFSSLFISIIIAFIYNVNLLKNLFKDMLLLRSYELESMIKRNLAEMIPDTLEDDNKVVKTKLLNKDELIDKYIFAEHSASLEILKELVKNKNSTDETYDCMERDLSIINGIFSKNGIILSANGIMNVYSRIGKRYILFEKNSTEDNDDDFFRSILSIEKSITGELLKKIIFLEDRMIDKSNYIPILLDTLHLIDANEDSIIIRKYIFKLTFSSVINEIIYDIISFYNVRFREDERIDLPYVTKLLNLEGCVLHKLVSIVVRSDDDAVPIYYNSKLVLREIFEMFSKNNIDLSFLQFKNIYLRLLENFYGINSGNLTREIIDEITNSHRIERSVITQIVSEELENFNNGEEQEGPTDINSVKDKVAQQLQSRNITLEQHKVDKIVHRIHRYVTDDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX13</accession>
    <name>A0A1J1GX13_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Proline--tRNA ligase, putative</fullName>
            <ecNumber evidence="7">6.1.1.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00438100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.15" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529603.1">
        <property type="nucleotide sequence ID" value="XM_028673118.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX13"/>
    <dbReference type="GeneID" id="39732914"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00438100"/>
    <dbReference type="OMA" id="HEFQVLC"/>
    <dbReference type="OrthoDB" id="10267474at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004827">
        <property type="term" value="F:proline-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006433">
        <property type="term" value="P:prolyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050062">
        <property type="entry name" value="Pro-tRNA_synthetase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42753">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME PROTEIN L39/PROLYL-TRNA LIGASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42753:SF2">
        <property type="entry name" value="PROLINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="6">
        <location>
            <begin position="94"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="381"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="537" mass="64073" checksum="B2F436311C18826B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX62</accession>
    <name>A0A1J1GX62_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Translation initiation factor SUI1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00464300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Probably involved in translation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SUI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529866.1">
        <property type="nucleotide sequence ID" value="XM_028673411.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX62"/>
    <dbReference type="GeneID" id="39733176"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00464300"/>
    <dbReference type="OMA" id="VENHIHI"/>
    <dbReference type="OrthoDB" id="10248435at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11566">
        <property type="entry name" value="eIF1_SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.780.10:FF:000001">
        <property type="entry name" value="Eukaryotic translation initiation factor SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.780.10">
        <property type="entry name" value="SUI1-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001950">
        <property type="entry name" value="SUI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036877">
        <property type="entry name" value="SUI1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005874">
        <property type="entry name" value="SUI1_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01160">
        <property type="entry name" value="SUI1_MOF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10388">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01253">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004499">
        <property type="entry name" value="SUI1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55159">
        <property type="entry name" value="eIF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50296">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SUI1" evidence="4">
        <location>
            <begin position="33"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="115" mass="12879" checksum="A7FF9E6D02807354" modified="2017-02-15" version="1">MNLAIQNLGINDPFTNENIVDKGNGKSNTTNLIHIRNQQRNGRKSVTTVQGLGKAYDLKKMVRALKKEFNCNGTIIEDIEHGSIIQLQGDKRNNVKDFLIREGICAVEHIRIHGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXC1</accession>
    <name>A0A1J1GXC1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 7">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00468100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 7"/>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529903.1">
        <property type="nucleotide sequence ID" value="XM_028673452.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXC1"/>
    <dbReference type="GeneID" id="39733214"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00468100"/>
    <dbReference type="OMA" id="ICVASMK"/>
    <dbReference type="OrthoDB" id="1902587at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.40:FF:000043">
        <property type="entry name" value="Peptidylprolyl isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050754">
        <property type="entry name" value="FKBP4/5/8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46512">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46512:SF9">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 7" id="KW-0697">Rotamase</keyword>
    <keyword evidence="4 8" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="9">
        <location>
            <begin position="37"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="227"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG97100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="303" mass="34691" checksum="B686816584C4B00A" modified="2017-02-15" version="1">MENTENYEQIHLTGDGGVIKTILRRGDEGEENIPKKGNEVTVHYVGKLESNGKVFDSSLDRNVPFKFHLGQGEVIKGWDICVASMKKNEKCSVRLDSKYGYGEEGCGENIPGNSVLIFEIELLSFREAKKSIYDYTDEEKIQAAFDLKEEGNELFKKDQIDEAISKYKEALDFFMHAEEWEDKLLEKKKNIEIICNLNLSTCYNKNKDYPNAIEHASKVLKLDKNNFKALYKLGVANMHFGFLEEAKDNLYKAASLNPKNLEIRNNYELCITKLKEARKKDKITFGGMFNKGSLYDEKESSAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXD0</accession>
    <name>A0A1J1GXD0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Phosphatidylinositol N-acetylglucosaminyltransferase subunit P, putative</fullName>
            <ecNumber evidence="7">2.4.1.198</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00448500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.198" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529707.1">
        <property type="nucleotide sequence ID" value="XM_028673234.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXD0"/>
    <dbReference type="GeneID" id="39733018"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00448500"/>
    <dbReference type="OMA" id="YWAAIIP"/>
    <dbReference type="OrthoDB" id="690928at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017176">
        <property type="term" value="F:phosphatidylinositol N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052263">
        <property type="entry name" value="GPI_Anchor_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013717">
        <property type="entry name" value="PIG-P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46346">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46346:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08510">
        <property type="entry name" value="PIG-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="PIG-P" evidence="6">
        <location>
            <begin position="6"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG96904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="121" mass="14385" checksum="FBA7B76C3F8521B3" modified="2017-02-15" version="1">MSSIKEGYAFFTLYLSQILWTLYLIWAFVFDDILNLLYFPFPSKYWAAIIPTAILFSILCFFLFIAIFSLIKTEPINSINLIKDEHSVFEDKLTENSMNYMNDIKIEQINKLLYETSLYFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="37" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXG8</accession>
    <name>A0A1J1GXG8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">CCR4-NOT transcription complex subunit 4, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">NOT4</name>
        <name evidence="14" type="ORF">PGAL8A_00457000</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529793.1">
        <property type="nucleotide sequence ID" value="XM_028673330.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733103"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00457000"/>
    <dbReference type="OMA" id="NIYNIHE"/>
    <dbReference type="OrthoDB" id="1923159at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030014">
        <property type="term" value="C:CCR4-NOT complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16618">
        <property type="entry name" value="mRING-HC-C4C4_CNOT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12438">
        <property type="entry name" value="RRM_CNOT4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000006">
        <property type="entry name" value="CCR4-NOT transcription complex subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000416">
        <property type="entry name" value="CCR4-NOT transcription complex subunit 4, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034261">
        <property type="entry name" value="CNOT4_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039780">
        <property type="entry name" value="Mot2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039515">
        <property type="entry name" value="NOT4_mRING-HC-C4C4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12603">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12603:SF0">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14570">
        <property type="entry name" value="zf-RING_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="12">
        <location>
            <begin position="115"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="13">
        <location>
            <begin position="226"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="24"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="606"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="761"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="830"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="451"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="43"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="606"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="761"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="830"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="842"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="869"/>
            <end position="1018"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG96990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1414" mass="169788" checksum="B7BA8F97EDB0F3C9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXI2</accession>
    <name>A0A1J1GXI2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00321000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000047">
        <property type="protein sequence ID" value="CRG95997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528805.1">
        <property type="nucleotide sequence ID" value="XM_028672232.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXI2"/>
    <dbReference type="GeneID" id="39731743"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00321000"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="353"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="376"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="872" mass="102267" checksum="5D55AC2C69B754D5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXI5</accession>
    <name>A0A1J1GXI5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00477800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530002.1">
        <property type="nucleotide sequence ID" value="XM_028673562.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXI5"/>
    <dbReference type="GeneID" id="39733311"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00477800"/>
    <dbReference type="OMA" id="RIKNCNH"/>
    <dbReference type="OrthoDB" id="447200at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="501" mass="60227" checksum="45AA8D0BAEA965B8" modified="2017-02-15" version="1">MEEEKEENKKVAVTKNIIYNNFQNRGFLNNFNFFQENIINLDKSLEYNCNVLNKKLEYGKIFEKNNYKGKNKKKLIIHLIPSENSKFYNFLHKKKQEILKKYGKDETYKYDIHISLTGYFFCDNVNVFLNTLYIYMFYYVKLYYMSKNLSFNHLFFNISCNSNNYSICIKNNKNGDKEKKIIFEREENKEKIDKKKKKFLNEENDNTKSDAHVLITNDGYVIIPILCEWVKRIFENFSFLIKNNNFISNSKYKNINKLGSNYMYKNSIISENFKEKHKNDSKLFLSNSILKNKYKKDLINSNSLYTNNVICSNIKNNNKISELFVSFEEETKKNSNDSNITFYDPNNNSSENVFNKYTDNYSIFEKVETGNYNINYNKRLMESNNCNNKKIKRLKKYNKNNNNNDKKDEKKNKIKYKYNNTEVNLTEFRIKECNHISLASNRNNKEVQKDIASMFKDLKYYFSNCSWDMVMFECDEKQFPQEKIKNNFLNEIFRFKKFAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXP6</accession>
    <name>A0A1J1GXP6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Formin 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00484300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530066.1">
        <property type="nucleotide sequence ID" value="XM_028673633.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXP6"/>
    <dbReference type="GeneID" id="39733376"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00484300"/>
    <dbReference type="OMA" id="HSIWEYS"/>
    <dbReference type="OrthoDB" id="524326at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00052">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000261">
        <property type="entry name" value="EH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216">
        <property type="entry name" value="EH DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216:SF174">
        <property type="entry name" value="GH06923P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12763">
        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00027">
        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50031">
        <property type="entry name" value="EH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EH" evidence="4">
        <location>
            <begin position="48"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="EH" evidence="4">
        <location>
            <begin position="163"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="201"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="345"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="549"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="612"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="351"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="395"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="405"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="479"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="872" mass="105550" checksum="921015063032FAFC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXQ5</accession>
    <name>A0A1J1GXQ5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Potassium channel tetramerisation-type BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00460400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529827.1">
        <property type="nucleotide sequence ID" value="XM_028673368.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXQ5"/>
    <dbReference type="GeneID" id="39733137"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00460400"/>
    <dbReference type="OMA" id="YRNSRLC"/>
    <dbReference type="OrthoDB" id="2414723at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051260">
        <property type="term" value="P:protein homooligomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18316">
        <property type="entry name" value="BTB_POZ_KCTD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003131">
        <property type="entry name" value="T1-type_BTB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14499:SF136">
        <property type="entry name" value="GH08630P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14499">
        <property type="entry name" value="POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02214">
        <property type="entry name" value="BTB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Potassium channel tetramerisation-type BTB" evidence="1">
        <location>
            <begin position="10"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="410" mass="48722" checksum="2850A73707142A0A" modified="2017-02-15" version="1">MDKLNRNDIIRINVGGKIYMTTLKLICRYKNSHLYKIVFEKLKEIQDYATNDFNKREIFIDRNGNRFEYILDFLRDGVLICENDINLLTRILIEAIYFKLFSLIKIIKKKISLLYSSMDSIINKKILKSIINSIEKKGKVKTVRLKKLTEDVSEHSELKYFNFKKKKKHRINFLNTVNVVNDVEKENSNLNEHLDDKINIRNMNTINSTEIYKNKDEIMFNKSVNFEENITNNENNIMNMNIKKDEKNSSNGILYMNNANTSDEYNITNNYLNKGEKIYNKNYIYRNYLKNDNKEDNFIPLENKKLKNIDSKSVSFSENNKFFLYNNNDISAFNDDDQINENFRKFHYDINDTNHTNYNNNNNYKHNNINKSKNHILVYSEIDDVEETSHFPIVSNVNLGEQIFSTTVDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXS0</accession>
    <name>A0A1J1GXS0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00462800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529851.1">
        <property type="nucleotide sequence ID" value="XM_028673394.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXS0"/>
    <dbReference type="GeneID" id="39733161"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00462800"/>
    <dbReference type="OMA" id="GNMFFLS"/>
    <dbReference type="OrthoDB" id="390191at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="64" mass="7576" checksum="13132CC6037945CD" modified="2017-02-15" version="1">MIDNKSLSKESDLITKLNYKNINDVSIHELNYLKNNREVYLKRGNMFFLSTKEEALNVLKNKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXS9</accession>
    <name>A0A1J1GXS9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin-conjugating enzyme E2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00464400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529867.1">
        <property type="nucleotide sequence ID" value="XM_028673412.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXS9"/>
    <dbReference type="GeneID" id="39733177"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00464400"/>
    <dbReference type="OMA" id="WNPTSHY"/>
    <dbReference type="OrthoDB" id="5596422at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd23814">
        <property type="entry name" value="UEV_AKTIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBC core" evidence="2">
        <location>
            <begin position="100"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="326"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="475"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="524"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="534" mass="63315" checksum="A24924E7FF18F102" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXX2</accession>
    <name>A0A1J1GXX2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00473300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529953.1">
        <property type="nucleotide sequence ID" value="XM_028673507.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXX2"/>
    <dbReference type="GeneID" id="39733266"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00473300"/>
    <dbReference type="OMA" id="SNCVISI"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="171" mass="20602" checksum="E285D1F7BFD57200" modified="2017-02-15" version="1">MDSITSKLQNNLQQFKDSTSSSSNCVISILESLLPVKPQNIEEVLFIIMFAIFFYIWISVFCNGNNIEYSRRLAYSNVQVITENKTKEAFLRSKRKRRNKIMEGVREREERRREIRRFIEKLKEQQEENIRIRERIKRREGQIAKRKKKLEKMKSSTGETENEYKEIEENE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY19</accession>
    <name>A0A1J1GY19_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA transcription, translation and transport factor protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00339400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528981.1">
        <property type="nucleotide sequence ID" value="XM_028672428.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY19"/>
    <dbReference type="GeneID" id="39731924"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00339400"/>
    <dbReference type="OMA" id="FAYITRY"/>
    <dbReference type="OrthoDB" id="514167at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019265">
        <property type="entry name" value="RTRAF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10036">
        <property type="entry name" value="RLL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="279" mass="33257" checksum="0A61BC1559681466" modified="2017-02-15" version="1">MNSLEKKIKLLNYENIDIAKDDFYFMILKIEEEKIRLYKPKEREKINYMKEKNYIEHIIKYLKKLNINTNGINKNSINDIEIRTYILNNLTTLALIDDYKDFICYDDEDEDDMNNKRIDNNNSVGEPSNSNVENMRNEIQDDILENFFELKYLNGIDKEEYKKYDKKLNILYEKINEIFKKNDIPLLNSSNISNIISALHLINEKLKNNKKIDNSNYESLFGLNIDVSNNDLKDFAYILKYLFNNMLKKRKKCIKNVLNEIQILTHNPVIDIKQGRVGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY22</accession>
    <name>A0A1J1GY22_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00376300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000086">
        <property type="protein sequence ID" value="CRG97160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529963.1">
        <property type="nucleotide sequence ID" value="XM_028673518.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY22"/>
    <dbReference type="GeneID" id="39732293"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00376300"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="296"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="334" mass="38375" checksum="0FD6F5993C7743EE" modified="2017-02-15" version="1">MALLYNEGCENPEKDITKCNVTACVLHGSKFKSVECDPAFKTVVKYSQKNSGDDIKKNIFVFEDTPPPYKNDAKITFLSQDSNNDIVFLYEVNPKSGYASSLVYLCRFRNLKPGLSLCQEVEKTHIGRPLSFNTIDILDRDNENNFQIGLKYLKNKRHATHKAKYEDIFFSKDSCHYVTEGNSSEQVCRYSICKKNSNGNIFCKDAKFNGKLCQLEPYNGLTAPTKFVYLPNSCIKESPNYCTPYLCQYEKPNELYPCSKLEISTIKDVVPHSQSLALASKQDRYISNEDNTSSSLIAMSFFPFLILFFFVGCYLYKVLRRNRKKKRYASYKEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYB0</accession>
    <name>A0A1J1GYB0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HORMA domain protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00482700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530051.1">
        <property type="nucleotide sequence ID" value="XM_028673616.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYB0"/>
    <dbReference type="GeneID" id="39733360"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00482700"/>
    <dbReference type="OMA" id="IWHCTNI"/>
    <dbReference type="OrthoDB" id="21254at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016035">
        <property type="term" value="C:zeta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.900.10">
        <property type="entry name" value="HORMA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003511">
        <property type="entry name" value="HORMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036570">
        <property type="entry name" value="HORMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045091">
        <property type="entry name" value="Mad2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11842">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11842:SF10">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56019">
        <property type="entry name" value="The spindle assembly checkpoint protein mad2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50815">
        <property type="entry name" value="HORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HORMA" evidence="1">
        <location>
            <begin position="1"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="193" mass="23671" checksum="5CE947B43E31EEA7" modified="2017-02-15" version="1">METYLLEFIEAFTHLILYITNVYSYEYFEKRRKLNTLIWHCTNIQVEKYIQQALYPIKRILLNKSLYKYRITLKDLKNEVLNIFTIEFEQFYKTYAQFSYSSFEQFVWDFFTYIEMQIYEYYDTEKTFEISFDVLKDENDFSLNESLRDDWELISYDNLEVFDKKILKSMNISDGNVSNPICQIYVESRKSVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYK5</accession>
    <name>A0A1J1GYK5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Amino acid transporter, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00360000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529181.1">
        <property type="nucleotide sequence ID" value="XM_028672650.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732130"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00360000"/>
    <dbReference type="OMA" id="CDYDQIR"/>
    <dbReference type="OrthoDB" id="6581954at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035725">
        <property type="term" value="P:sodium ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616:SF240">
        <property type="entry name" value="BLOATED TUBULES, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11616">
        <property type="entry name" value="SODIUM/CHLORIDE DEPENDENT TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SNF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="632"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="662"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="700"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="827"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="857"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="900"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="940"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1029"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1068"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1093"/>
            <end position="1121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1133"/>
            <end position="1154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1160"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1248"/>
            <end position="1270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1377"/>
            <end position="1400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="368"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="368"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="413"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="523"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1519" mass="182218" checksum="83725942C6D0CA17" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYR6</accession>
    <name>A0A1J1GYR6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">10 kDa chaperonin, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00529900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GroES chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530523.1">
        <property type="nucleotide sequence ID" value="XM_028674140.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYR6"/>
    <dbReference type="GeneID" id="39733832"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00529900"/>
    <dbReference type="OMA" id="KERPMQG"/>
    <dbReference type="OrthoDB" id="184876at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00320">
        <property type="entry name" value="cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.33.40:FF:000002">
        <property type="entry name" value="10 kDa chaperonin, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.33.40">
        <property type="entry name" value="GroES chaperonin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00580">
        <property type="entry name" value="CH10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020818">
        <property type="entry name" value="Chaperonin_GroES"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037124">
        <property type="entry name" value="Chaperonin_GroES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018369">
        <property type="entry name" value="Chaprnonin_Cpn10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772">
        <property type="entry name" value="10 KDA HEAT SHOCK PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772:SF0">
        <property type="entry name" value="10 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00166">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00297">
        <property type="entry name" value="CHAPERONIN10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00883">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00681">
        <property type="entry name" value="CHAPERONINS_CPN10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="102" mass="11028" checksum="0C92DA9668A36F67" modified="2017-02-15" version="1">MSSTIAKKFIPLMDRILISKIVPKTTTKSGLFLPESATEPSYTGKVLAVGPGRITSNGNKIPPSVKEGDVVVLPEYGGSSLKIDGEEFFVYRDDDIIGILRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ29</accession>
    <name>A0A1J1GZ29_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00506200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530290.1">
        <property type="nucleotide sequence ID" value="XM_028673882.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ29"/>
    <dbReference type="GeneID" id="39733595"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00506200"/>
    <dbReference type="OMA" id="FKSTYEC"/>
    <dbReference type="OrthoDB" id="372066at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="573"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="999" mass="120552" checksum="03831569EF7A9960" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ37</accession>
    <name>A0A1J1GZ37_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00530200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SDHAF4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530526.1">
        <property type="nucleotide sequence ID" value="XM_028674144.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ37"/>
    <dbReference type="GeneID" id="39733835"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00530200"/>
    <dbReference type="OMA" id="CPKNENA"/>
    <dbReference type="OrthoDB" id="387655at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012875">
        <property type="entry name" value="SDHF4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07896">
        <property type="entry name" value="DUF1674"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="97"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="159" mass="19486" checksum="3496D0BC9510BAF4" modified="2017-02-15" version="1">MKKLYCEIFKKKNNFFLNNNSYLNYGINRIITGEYVKFYTKRDFLKLRKFNYKNLSTFEKNKINVNKKEDINVKEYNYSKKMNIKENMLKNESYSKKENLDKNIVEKKETLNEDKKEKKEKEKKNDLIKSLSEEFGYKYEKHEPTMFGDWSHNCRVTDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ97</accession>
    <name>A0A1J1GZ97_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L35</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00420500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529429.1">
        <property type="nucleotide sequence ID" value="XM_028672925.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ97"/>
    <dbReference type="GeneID" id="39732737"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00420500"/>
    <dbReference type="OrthoDB" id="162638at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.410.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00514">
        <property type="entry name" value="Ribosomal_bL35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001706">
        <property type="entry name" value="Ribosomal_bL35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021137">
        <property type="entry name" value="Ribosomal_bL35-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018265">
        <property type="entry name" value="Ribosomal_bL35_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037229">
        <property type="entry name" value="Ribosomal_bL35_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00001">
        <property type="entry name" value="rpmI_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33343">
        <property type="entry name" value="54S RIBOSOMAL PROTEIN BL35M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33343:SF1">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL35M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01632">
        <property type="entry name" value="Ribosomal_L35p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00064">
        <property type="entry name" value="RIBOSOMALL35"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143034">
        <property type="entry name" value="L35p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00936">
        <property type="entry name" value="RIBOSOMAL_L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012723837" description="50S ribosomal protein L35" evidence="5">
        <location>
            <begin position="21"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="152" mass="18063" checksum="D178E1F4F5A03B38" modified="2017-02-15" version="1">MKYFLLVLIIFIFFLDFSDGKKNIISKQLYLNKINENLKGKINYINFLKNKCIEKEKKKLYKFLFIKMNSNFIKNFHTFKLNVRGSTDIKPKTNKSIAKRFKITKNGKLIRKKAGRNHMLRKKTSSNKSSLRKRTTIASNRIAKKYKSVIFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZE0</accession>
    <name>A0A1J1GZE0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Cation transporting P-ATPase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ATPase3</name>
        <name evidence="14" type="ORF">PGAL8A_00025200</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530617.1">
        <property type="nucleotide sequence ID" value="XM_028674245.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728775"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00025200"/>
    <dbReference type="OMA" id="CGKIRIF"/>
    <dbReference type="OrthoDB" id="289856at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140358">
        <property type="term" value="F:P-type transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006544">
        <property type="entry name" value="P-type_TPase_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630">
        <property type="entry name" value="CATION-TRANSPORTING ATPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630:SF11">
        <property type="entry name" value="CATION-TRANSPORTING P-TYPE ATPASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="392"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="611"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="638"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1658"/>
            <end position="1677"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1724"/>
            <end position="1749"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1775"/>
            <end position="1795"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1807"/>
            <end position="1825"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1879"/>
            <end position="1900"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="13">
        <location>
            <begin position="427"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="865"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1330"/>
            <end position="1350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1377"/>
            <end position="1403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1340"/>
            <end position="1350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG97817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1921" mass="227469" checksum="8F9C3828318C1BA2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZF0</accession>
    <name>A0A1J1GZF0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00361900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529200.1">
        <property type="nucleotide sequence ID" value="XM_028672671.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZF0"/>
    <dbReference type="GeneID" id="39732149"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00361900"/>
    <dbReference type="OMA" id="FRLNAHK"/>
    <dbReference type="OrthoDB" id="373479at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="174" mass="20636" checksum="2D171CEEB8BA329F" modified="2017-02-15" version="1">MASLKNATGVRHNVFRLNAHKKIIYNRMRRFNWPPKECSTIHPIEPYGKQFFIFNAFKRDTKFDNEISNTVTPLINSNNEKIPSETVLCVCDFAKRPLMFLNYLDFKILQANMNKIKEGFRKIEEKLDKSNYLDTKFGLMLKYNLNKTYGMQRVKKGEHNSWGMKKGVFRQRKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZG4</accession>
    <name>A0A1J1GZG4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Palmitoyltransferase</fullName>
            <ecNumber evidence="10">2.3.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00519000</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="10"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530418.1">
        <property type="nucleotide sequence ID" value="XM_028674024.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZG4"/>
    <dbReference type="GeneID" id="39733723"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00519000"/>
    <dbReference type="OMA" id="ETKINCF"/>
    <dbReference type="OrthoDB" id="4096362at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883:SF43">
        <property type="entry name" value="PALMITOYLTRANSFERASE APP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22883">
        <property type="entry name" value="ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0564">Palmitate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="34"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="182"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="226"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="833"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="12">
        <location>
            <begin position="134"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="338"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG97617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="856" mass="102018" checksum="54ED3B0DA87C653A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZP0</accession>
    <name>A0A1J1GZP0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">S-adenosylmethionine synthase</fullName>
            <ecNumber evidence="10">2.5.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">SAMS</name>
        <name evidence="15" type="ORF">PGAL8A_00435100</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the formation of S-adenosylmethionine from methionine and ATP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-methionine + ATP + H2O = S-adenosyl-L-methionine + phosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21080"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.5.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="10">Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the AdoMet synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.6" evidence="10"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529573.1">
        <property type="nucleotide sequence ID" value="XM_028673084.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZP0"/>
    <dbReference type="SMR" id="A0A1J1GZP0"/>
    <dbReference type="GeneID" id="39732883"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00435100"/>
    <dbReference type="OMA" id="ASYMARY"/>
    <dbReference type="OrthoDB" id="5852090at2759"/>
    <dbReference type="UniPathway" id="UPA00315">
        <property type="reaction ID" value="UER00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004478">
        <property type="term" value="F:methionine adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006556">
        <property type="term" value="P:S-adenosylmethionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd18079">
        <property type="entry name" value="S-AdoMet_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.10:FF:000003">
        <property type="entry name" value="S-adenosylmethionine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.10:FF:000004">
        <property type="entry name" value="S-adenosylmethionine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00086">
        <property type="entry name" value="S_AdoMet_synth1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022631">
        <property type="entry name" value="ADOMET_SYNTHASE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022630">
        <property type="entry name" value="S-AdoMet_synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022629">
        <property type="entry name" value="S-AdoMet_synt_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022628">
        <property type="entry name" value="S-AdoMet_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002133">
        <property type="entry name" value="S-AdoMet_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022636">
        <property type="entry name" value="S-AdoMet_synthetase_sfam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01034">
        <property type="entry name" value="metK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11964">
        <property type="entry name" value="S-ADENOSYLMETHIONINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02773">
        <property type="entry name" value="S-AdoMet_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02772">
        <property type="entry name" value="S-AdoMet_synt_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00438">
        <property type="entry name" value="S-AdoMet_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000497">
        <property type="entry name" value="MAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55973">
        <property type="entry name" value="S-adenosylmethionine synthetase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00376">
        <property type="entry name" value="ADOMET_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00377">
        <property type="entry name" value="ADOMET_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 10" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="9 10" id="KW-0630">Potassium</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S-adenosylmethionine synthetase N-terminal" evidence="12">
        <location>
            <begin position="10"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="S-adenosylmethionine synthetase central" evidence="13">
        <location>
            <begin position="123"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="S-adenosylmethionine synthetase C-terminal" evidence="14">
        <location>
            <begin position="248"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG96769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="402" mass="44911" checksum="0C0387E7419C941A" modified="2017-02-15" version="1">MSQLKIKRGNFLFTSESVNEGHPDKICDQISDAILDYCLREDPDSKVACEVCAKNNFIFIFGEITTKAKVDYDKVARDVLKHIGYDDESKGLDYKTAKIKVSVDEQSPDIAQCVHENKSPELIGAGDQGIMFGYATDETENYMPLTHHYATLLGKRLTEVRKLGILPYLGPDGKTQITIEYKNKGSCGGHMEPLRVHTVLISTQHSENIKHEQLKSDLMENVVKYVIPEKLLDKDTFYYLNPSGKFVIGGPAADAGLTGRKIICDTYGGWGAHGGGAFSGKDASKVDRSAAYYLRYIAKSLVANKFCRRVLVQASYSIGIANPISLNVNSYGTVTTGYTDYDLEQIILRNFDLRPGFIIEELKLKQPIFSKTSAYGHFGRNDDSFTWEKVKDLTHEKNVLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZY4</accession>
    <name>A0A1J1GZY4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00061900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530979.1">
        <property type="nucleotide sequence ID" value="XM_028674648.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZY4"/>
    <dbReference type="GeneID" id="39729144"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00061900"/>
    <dbReference type="OMA" id="IYIRIDH"/>
    <dbReference type="OrthoDB" id="377517at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="entry name" value="TATA-Binding Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55945">
        <property type="entry name" value="TATA-box binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG98182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="656" mass="78531" checksum="FF06EDB22D9F42C0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZZ8</accession>
    <name>A0A1J1GZZ8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00030800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530672.1">
        <property type="nucleotide sequence ID" value="XM_028674305.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZZ8"/>
    <dbReference type="GeneID" id="39728831"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00030800"/>
    <dbReference type="OMA" id="YNECALT"/>
    <dbReference type="OrthoDB" id="376001at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="327" mass="38450" checksum="EEE87696100A6B7D" modified="2017-02-15" version="1">MRHELSSIFQSKNLDEQSFKQNNDYLNNNEALESYLNFYSSPGFYVEPVNFELNPLNVVDINNLLGDTEQNVFNNVDLKNLDTLENNTNALNTSATDFKEYKNDNINITSENVCDFEKDFKQNVEYFEIEKNNNLEVENETKNAIIEDEENLEIKENELNHQNYFNLINEDKNKKDNFELNESNILPLSYTNENEMMYNECALTNDFFETIENINTKVFEKYNNLKDMTENLIDIINKSEFEKRINNLLDLSDNNSELIDKFKKKSEDCIRQCRKFETTSESLIGECVNTLAQTSICYAEWVCLHSFEMDSIDNDLKEIQLFIETSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H026</accession>
    <name>A0A1J1H026_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">histidine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00447100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>tRNA(His) + L-histidine + ATP = L-histidyl-tRNA(His) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17313"/>
            <dbReference type="Rhea" id="RHEA-COMP:9665"/>
            <dbReference type="Rhea" id="RHEA-COMP:9689"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78527"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.21"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.21" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529693.1">
        <property type="nucleotide sequence ID" value="XM_028673218.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H026"/>
    <dbReference type="GeneID" id="39733004"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00447100"/>
    <dbReference type="OMA" id="NYRAICG"/>
    <dbReference type="OrthoDB" id="1906957at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004821">
        <property type="term" value="F:histidine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006427">
        <property type="term" value="P:histidyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041715">
        <property type="entry name" value="HisRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004516">
        <property type="entry name" value="HisRS/HisZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43707:SF1">
        <property type="entry name" value="HISTIDINE--TRNA LIGASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43707">
        <property type="entry name" value="HISTIDYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13393">
        <property type="entry name" value="tRNA-synt_His"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001549">
        <property type="entry name" value="His-tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core" evidence="4">
        <location>
            <begin position="156"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="118"/>
            <end position="120"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="341"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="345"/>
            <end position="346"/>
        </location>
        <ligand>
            <name>L-histidine</name>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00047639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001549-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="503" mass="60900" checksum="5456D07BC587429F" modified="2017-02-15" version="1">MLIKIIYLMIIIFLKIGSFKNIKEKKKFFFFFLLKTKNNYSLKKKFILNSVKGIRTFDSKNYQRREYLFKIWKNISKSFAYDFYDLPILENYDIFRKSNINESYDFVKNNRHLILRPEITPQLINYLFFKKNKLKEKNTNHDNNSQNYKKNYLLQNLKKVFKMCTIGQCFRYEKMSRCRKREHYQWNMDIIGIDNISAEIEIFTILISFFHYIKLIHNDIVFKINDKKIIHYIIFKIFKKSFDFSYNRTQLEIKKILHTLDKFHKINNYSFKLLLIKKCPYLKKRDIQLFNNVIHNITTLNQLEVYLNFNTSIYNDLKNLLSYFQKLNLHPFFQIDTTIVRGLDYYNNIIFEIFYKHKNYRAICGGGRYDFFLDGKKIFAVGFAMGDIVISEILFKNFMKETNLHKNINVVSFFPFIVKENIEDIHKEYYSILNILRNNNVKVYSLLQNNLKLSKALKKANSLNPDYFLFFQEKDNIIFLKNLKTRKQIAVNSQNILSAYNNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H048</accession>
    <name>A0A1J1H048_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00424000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529464.1">
        <property type="nucleotide sequence ID" value="XM_028672963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H048"/>
    <dbReference type="GeneID" id="39732772"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00424000"/>
    <dbReference type="OrthoDB" id="391731at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1370">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="176"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="204" mass="24299" checksum="5F299E1788092485" modified="2017-02-15" version="1">MADKICHKLINENLKTLCEHTLPNKNDYEIKNEKFNNININCSSKCEELCNNINERLQKIKDIVHLRSTRPNVILIDTLKYIKEYIKEIEKYIEIFNNVIHEENKAYAYFEDIFNSLNIQNQNVQKIYHICSKNIVITKNNNELILQKPQSYFSLSSKFVNNLLNICKEQNEKINENNNENQNENKNIIENENENKNKNDNYLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H060</accession>
    <name>A0A1J1H060_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00424800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529472.1">
        <property type="nucleotide sequence ID" value="XM_028672972.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732780"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00424800"/>
    <dbReference type="OMA" id="VNICNLY"/>
    <dbReference type="OrthoDB" id="392410at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1111"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1278"/>
            <end position="1297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="616"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="853"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="631"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1404" mass="167684" checksum="5E7DF57DCD490175" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0B9</accession>
    <name>A0A1J1H0B9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pentatricopeptide repeat protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00455000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529773.1">
        <property type="nucleotide sequence ID" value="XM_028673306.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0B9"/>
    <dbReference type="GeneID" id="39733083"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00455000"/>
    <dbReference type="OMA" id="HKVFHFY"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF24">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="411"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="509"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="411"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="427"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1267" mass="151707" checksum="B54CEB918650900F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0G7</accession>
    <name>A0A1J1H0G7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cg6 protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">GLP3</name>
        <name evidence="8" type="ORF">PGAL8A_00049400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530856.1">
        <property type="nucleotide sequence ID" value="XM_028674511.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0G7"/>
    <dbReference type="GeneID" id="39729019"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00049400"/>
    <dbReference type="OrthoDB" id="415696at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03028">
        <property type="entry name" value="GRX_PICOT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033658">
        <property type="entry name" value="GRX_PICOT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004480">
        <property type="entry name" value="Monothiol_GRX-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293">
        <property type="entry name" value="GLUTAREDOXIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293:SF72">
        <property type="entry name" value="MONOTHIOL GLUTAREDOXIN-S14, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="7">
        <location>
            <begin position="208"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="139"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="143"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG98059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="295" mass="34853" checksum="1B1ACECB6B65600F" modified="2017-02-15" version="1">MNRYKKATNIIYLYSVYNIYSNCMDHISENIFQLKISTKLQNVMTFCENRNNKNNIKYEKSSDTILKIFENEKKKNSITPKEIQKKKFIDNLNYKNVLNNENSLTNEKGENEKNSNYEDNFVSNEKDYFNTINKSNKLFNETKSNEKNEEKTMNNNKNDDKINNYESYDTEKNNKEEGGDINTMNKSEDELNEDMINLIENILKKHNIVLFMKGTALNPFCKYSKQAIHILKLNKVKEIHTVNILDNEKLRNSLKIYSKWPTFPQLYINSKFIGGIDKVQELHDSNKLKELIENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0K4</accession>
    <name>A0A1J1H0K4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Zinc finger protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00463800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529861.1">
        <property type="nucleotide sequence ID" value="XM_028673405.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0K4"/>
    <dbReference type="GeneID" id="39733171"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00463800"/>
    <dbReference type="OMA" id="VDHRRKW"/>
    <dbReference type="OrthoDB" id="30343at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:000491">
        <property type="entry name" value="zinc finger matrin-type protein 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040107">
        <property type="entry name" value="Snu23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45986">
        <property type="entry name" value="ZINC FINGER MATRIN-TYPE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45986:SF1">
        <property type="entry name" value="ZINC FINGER MATRIN-TYPE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="U1-type" evidence="6">
        <location>
            <begin position="102"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="182"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="188"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="232" mass="27611" checksum="DC709D4A1E3C4443" modified="2017-02-15" version="1">MNKKRSIDHQHENSDINKKKLNIDNYGRKVWDKEYYQKKVDEKVTNEEDELILKLLPDLKKPKVPPVLSERKLLEERKENLSLEKNLGKVQILTQKTPKEEQGGFYCKICECVIKDSQTYLDHINGKNHNRMLGYSMKVKRVTLDDVKKKLSTLKDKKDNKTKEIEKDAYEEAKKSMKEIQEMEERKIQKRKEKKLQKKLEKKKRKEELLSKLEEDTIHSEIKELGLPTSFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H139</accession>
    <name>A0A1J1H139_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00483800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530061.1">
        <property type="nucleotide sequence ID" value="XM_028673627.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H139"/>
    <dbReference type="GeneID" id="39733371"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00483800"/>
    <dbReference type="OrthoDB" id="377888at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="219" mass="26405" checksum="42D7F054B3C9A1E9" modified="2017-02-15" version="1">MKIKNFKIPIWSINKKRISFLKEFHFKFKKYENDRNEKHLYWPNKKSIFFLNKNELKNVDKKNVNKINTFKKEYKIYIAYYGVLITCFVAFSFCIIKLLFMIFEEPLPLKLVKEQVLKDKKLIDEYEGVIFSKFWTGYLNENDAKIMINIKSKKYNKKGKIISNLSKINDKWIIKTLTYYNVKKNDNLKTDDLKSLQNKSNSCPINNNMFCLKNEKIKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1A6</accession>
    <name>A0A1J1H1A6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Kinesin-13, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00465800</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529880.1">
        <property type="nucleotide sequence ID" value="XM_028673427.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1A6"/>
    <dbReference type="GeneID" id="39733191"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00465800"/>
    <dbReference type="OMA" id="WCESENL"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007019">
        <property type="term" value="P:microtubule depolymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01367">
        <property type="entry name" value="KISc_KIF2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000081">
        <property type="entry name" value="Kinesin-13, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47971:SF8">
        <property type="entry name" value="KINESIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47971">
        <property type="entry name" value="KINESIN-RELATED PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6 8" id="KW-0505">Motor protein</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="10">
        <location>
            <begin position="37"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="128"/>
            <end position="135"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG97077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1046" mass="121217" checksum="E7F3F45FC6B9BF09" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1N1</accession>
    <name>A0A1J1H1N1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="4">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">DLAT</name>
        <name evidence="8" type="ORF">PGAL8A_00480000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530024.1">
        <property type="nucleotide sequence ID" value="XM_028673586.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1N1"/>
    <dbReference type="GeneID" id="39733333"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00480000"/>
    <dbReference type="OMA" id="LYSKVEI"/>
    <dbReference type="OrthoDB" id="537444at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045254">
        <property type="term" value="C:pyruvate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004742">
        <property type="term" value="F:dihydrolipoyllysine-residue acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:pyruvate decarboxylation to acetyl-CoA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000010">
        <property type="entry name" value="Acetyltransferase component of pyruvate dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="entry name" value="E3-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045257">
        <property type="entry name" value="E2/Pdx1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151">
        <property type="entry name" value="DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151:SF75">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT 5 OF PYRUVATE DEHYDROGENASE COMPLEX, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 4" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012678600" description="Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex" evidence="5">
        <location>
            <begin position="18"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="6">
        <location>
            <begin position="52"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="6">
        <location>
            <begin position="169"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="7">
        <location>
            <begin position="347"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="623" mass="71707" checksum="0B6F3FC3BDD9BD95" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1R4</accession>
    <name>A0A1J1H1R4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">JAB1/MPN/MOV34 metalloenzyme domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00483300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530056.1">
        <property type="nucleotide sequence ID" value="XM_028673622.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1R4"/>
    <dbReference type="GeneID" id="39733366"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00483300"/>
    <dbReference type="OrthoDB" id="372413at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016563">
        <property type="entry name" value="Npl4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12710">
        <property type="entry name" value="NUCLEAR PROTEIN LOCALIZATION 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12710:SF0">
        <property type="entry name" value="NUCLEAR PROTEIN LOCALIZATION PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013153655" description="JAB1/MPN/MOV34 metalloenzyme domain-containing protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="493" mass="58015" checksum="D4A7BDA524647156" modified="2017-02-15" version="1">MKNNIILICIYFIFIKNICGGLKVHKIKENYFTISKNGGNTDIYKNNSSNNNIKKLGESKKENKFFHFENKKKISINPLFQSICKDVSVSETCLHNIQNFFSNVNYNNLKSKNSKESKYFCGVLYGKYENNEFIKIENVFFSMNISEGFYDIDYLLNSEDRKKADKLAKMLNLEVVGFLYAYPDIGVDINMANKKKKRYIKLNKKIKTLNDEENEIFIPMGGKEVLLSLMLMKQILDNSKKYSEKPNELHDNSNGNDQEENENDKYKKSKNDNYNINESKKRSLKKKKKKNSNIKPFIILSVGMSKNTDSIIVEAYEINYDLLKLVKHNIIKDMKKQNSILQFEKKQNEKEMKIKKFDSEVDIMNELYLKCKNNILIKKIELKKIDILFCVNNVPIFSHKSVYNYFFPYPSNDNYYNILQKFNNMIKTIDNKNDIVNVFRDFNFLFFLTNLFSIDHDFPYFCAAVNDITNSISIPDHYIYILKNLSKNTNILD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H1Z7</accession>
    <name>A0A1J1H1Z7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pre-mRNA-processing factor 40, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">PRP40</name>
        <name evidence="4" type="ORF">PGAL8A_00512800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530356.1">
        <property type="nucleotide sequence ID" value="XM_028673955.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H1Z7"/>
    <dbReference type="GeneID" id="39733661"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00512800"/>
    <dbReference type="OMA" id="RDEIFQD"/>
    <dbReference type="OrthoDB" id="187617at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.70.10:FF:000105">
        <property type="entry name" value="Pre-mRNA-processing factor 40, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.440">
        <property type="entry name" value="FF domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002713">
        <property type="entry name" value="FF_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036517">
        <property type="entry name" value="FF_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039726">
        <property type="entry name" value="Prp40-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11864">
        <property type="entry name" value="PRE-MRNA-PROCESSING PROTEIN PRP40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11864:SF0">
        <property type="entry name" value="PRP40 PRE-MRNA PROCESSING FACTOR 40 HOMOLOG A (YEAST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01846">
        <property type="entry name" value="FF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25432">
        <property type="entry name" value="FF_PRPF40A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00441">
        <property type="entry name" value="FF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81698">
        <property type="entry name" value="FF domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51676">
        <property type="entry name" value="FF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="235"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="278"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="FF" evidence="3">
        <location>
            <begin position="414"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="816"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="819"/>
            <end position="829"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="885" mass="105313" checksum="BA7C3C527D3B0CE5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2C8</accession>
    <name>A0A1J1H2C8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Small ribosomal subunit protein mS41 SAM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00505900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530287.1">
        <property type="nucleotide sequence ID" value="XM_028673879.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2C8"/>
    <dbReference type="GeneID" id="39733592"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00505900"/>
    <dbReference type="OMA" id="ISWKMKR"/>
    <dbReference type="OrthoDB" id="408360at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019083">
        <property type="entry name" value="SAM_Ribosomal_mS41"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09597">
        <property type="entry name" value="SAM_Ribosomal_mS41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Small ribosomal subunit protein mS41 SAM" evidence="2">
        <location>
            <begin position="69"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="259"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="321" mass="39305" checksum="968BE235E3B233A4" modified="2017-02-15" version="1">MNKSLIRFFKNIRLLHTSVFRRNSDDTGPLIKKKRRFFDLKLFRQHLRRQKTEEIEIEKKELLKSCAKEAPKNWDIRTFLEKIDIGENIDEIEKYFKSWQEFITITPKELYNIECLSNQQRRKIWKYVNKFNYGLYPEDSYDDFVKNFQAPPLENENKIWTKEDEQQLKYYLNYYDVNFGDPWLYISWKMKRTFDDVQNKYVELILKEKNKKRKCEICLTKCTTPLLMNRKFKLDPPFIFFIPSSFNFPPMTIYDYYKKKNSNNLNKNINENINEYDKNKHEKNEIFNLTEENLKKDPLYPSYASFIFSSKFLPFVNKNCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2F4</accession>
    <name>A0A1J1H2F4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cullin-like protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00525100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2 3">Belongs to the cullin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530476.1">
        <property type="nucleotide sequence ID" value="XM_028674089.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2F4"/>
    <dbReference type="GeneID" id="39733784"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00525100"/>
    <dbReference type="OMA" id="FKSNTHI"/>
    <dbReference type="OrthoDB" id="27073at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1310.10">
        <property type="entry name" value="Cullin Repeats"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.130">
        <property type="entry name" value="Cullin, Chain C, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045093">
        <property type="entry name" value="Cullin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059120">
        <property type="entry name" value="Cullin-like_AB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016158">
        <property type="entry name" value="Cullin_homology"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036317">
        <property type="entry name" value="Cullin_homology_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001373">
        <property type="entry name" value="Cullin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019559">
        <property type="entry name" value="Cullin_neddylation_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11932">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00888">
        <property type="entry name" value="Cullin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26557">
        <property type="entry name" value="Cullin_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10557">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00182">
        <property type="entry name" value="CULLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00884">
        <property type="entry name" value="Cullin_Nedd8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75632">
        <property type="entry name" value="Cullin homology domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50069">
        <property type="entry name" value="CULLIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cullin family profile" evidence="4">
        <location>
            <begin position="418"/>
            <end position="690"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="810" mass="97667" checksum="7E2CB3F6F7A266A8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2N5</accession>
    <name>A0A1J1H2N5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PPPDE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00532500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DeSI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530548.1">
        <property type="nucleotide sequence ID" value="XM_028674168.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2N5"/>
    <dbReference type="GeneID" id="39733858"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00532500"/>
    <dbReference type="OrthoDB" id="21221at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070646">
        <property type="term" value="P:protein modification by small protein removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1720.30">
        <property type="entry name" value="PPPDE domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008580">
        <property type="entry name" value="PPPDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042266">
        <property type="entry name" value="PPPDE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036339">
        <property type="entry name" value="PUB-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12378">
        <property type="entry name" value="DESUMOYLATING ISOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12378:SF7">
        <property type="entry name" value="DESUMOYLATING ISOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05903">
        <property type="entry name" value="Peptidase_C97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01179">
        <property type="entry name" value="DUF862"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143503">
        <property type="entry name" value="PUG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51858">
        <property type="entry name" value="PPPDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPPDE" evidence="4">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="389" mass="45449" checksum="CF301A67248D14D3" modified="2017-02-15" version="1" fragment="single">RVKTWSPLLIGKQIEGVWHTAVLVYNMEYFYGGGILCLDPKEFEAFYDINPVNIIDMGTTEIHQTYFHEYLNGIQKDFTVDKYNLVNWNCNNFTNEVCNFLVGKNIPEYILNTPYEVMSTSKGKLILDMMQSYQTMIAPGMEGSSLENNNSSENKSIHNKKDFCKLPSVTLDNFFDGNRVEDLIEEVIKNEKYNSNQKNTFLDTLKKILDDIVKNLDNLEYRVLYKNRCDIFNNLSTISEYNEILSSIGFFQGYIEKDEINNIQNFTIFIDSKRKGHSFSEHLNLFVNKKIFLKNENKTISKTSVLNFKDLIDYIPCLERKKNNSNDFLIFLSDAFINNNFDIINEKNDINYFKTIKEKMNVDPYIEKKFLLSTLEILKKNLSSLCSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H330</accession>
    <name>A0A1J1H330_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">EKC/KEOPS complex subunit CGI121, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">CGI121</name>
        <name evidence="6" type="ORF">PGAL8A_00033000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the CGI121/TPRKB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530692.1">
        <property type="nucleotide sequence ID" value="XM_028674328.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H330"/>
    <dbReference type="GeneID" id="39728853"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00033000"/>
    <dbReference type="OMA" id="FFLSAHE"/>
    <dbReference type="OrthoDB" id="329139at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000408">
        <property type="term" value="C:EKC/KEOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2380.10">
        <property type="entry name" value="CGI121/TPRKB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013926">
        <property type="entry name" value="CGI121/TPRKB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036504">
        <property type="entry name" value="CGI121/TPRKB_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15840">
        <property type="entry name" value="CGI-121 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15840:SF10">
        <property type="entry name" value="EKC_KEOPS COMPLEX SUBUNIT TPRKB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08617">
        <property type="entry name" value="CGI-121"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143870">
        <property type="entry name" value="PF0523-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="178" mass="21142" checksum="F60502720C96587A" modified="2017-02-15" version="1">MRKRELCILNNKLDTTLILFKNVVNAKNILESYNKHISDFNDTNHFFLLLDSELIFNENHILHSIYRAYYNFITKKRITKNMILEIFFLLSPHENINECLKQYQIKNDSSSIIYVGLNVTNEEIDTFVDLIEGERINFNEISFLHDKKKISDNFKCTDINNLEKFIYHNIASKKLNLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GKU4</accession>
    <name>A0A1J1GKU4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nucleolar Jumonji domain interacting protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00073600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat WDR55 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525854.1">
        <property type="nucleotide sequence ID" value="XM_028674978.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GKU4"/>
    <dbReference type="GeneID" id="39729261"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00073600"/>
    <dbReference type="OMA" id="GIIKHWD"/>
    <dbReference type="OrthoDB" id="2288928at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050505">
        <property type="entry name" value="WDR55/POC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44019">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44019:SF20">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24796">
        <property type="entry name" value="WDR55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="322" mass="36661" checksum="880EF3930ADC5662" modified="2017-02-15" version="1">MKGICVSIDCETLIFDLEFHPKLDMICAGLFNGNLILYKLNDDKKKFQKKWDVYNHEKALRCVTFSKNGNKILAASSDNNCSITDITGKVLWKNKCHDFTINSILFTSSNTFLTTDERGFIKHWDLRDESRNPIHKIKEFDDTISSMLLDPDEKSVVISSGGYIALYDILNKKKISSHSISTEYDDEFLSLQFIAHNTKIACATLNGYITIFSKKHWGNIEGKLKASKDIINTFVKLDEYTICYGTSDGIIKSAHLLPNKIGKSIGRHNGNDSIEKLAINKKKNLLASVSHDNSIKFYPIEIKNSHISNKMKKRTKSFFRDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL17</accession>
    <name>A0A1J1GL17_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Mitochondrial ribosomal protein S8, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00081600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525934.1">
        <property type="nucleotide sequence ID" value="XM_028670621.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL17"/>
    <dbReference type="GeneID" id="39729340"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00081600"/>
    <dbReference type="OrthoDB" id="409928at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000630">
        <property type="entry name" value="Ribosomal_uS8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035987">
        <property type="entry name" value="Ribosomal_uS8_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00410">
        <property type="entry name" value="Ribosomal_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56047">
        <property type="entry name" value="Ribosomal protein S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="129" mass="14801" checksum="DD70075DA221C23D" modified="2017-02-15" version="1">MQRACEMVVSLLRTDSMTQKCPFHVLNVQILELLQKEGLIRGFAIKGTKIDILLKHYKGAPVIRNIRVVSKPSRDIWLTPHELKFRTRFNTGLWVMQTSCGVISHRDCIRMGIGGKMLFAVNNGYQHFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL37</accession>
    <name>A0A1J1GL37_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00081400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525932.1">
        <property type="nucleotide sequence ID" value="XM_028670599.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729338"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00081400"/>
    <dbReference type="OrthoDB" id="371246at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1308" mass="155061" checksum="EC5A0DA64AC96658" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL51</accession>
    <name>A0A1J1GL51_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Apicoplast TIC22, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00076600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525882.1">
        <property type="nucleotide sequence ID" value="XM_028670044.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL51"/>
    <dbReference type="GeneID" id="39729291"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00076600"/>
    <dbReference type="OrthoDB" id="196308at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007378">
        <property type="entry name" value="Tic22-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33926">
        <property type="entry name" value="PROTEIN TIC 22, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33926:SF4">
        <property type="entry name" value="PROTEIN TIC 22, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04278">
        <property type="entry name" value="Tic22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0934">Plastid</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013244191" evidence="5">
        <location>
            <begin position="18"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="278" mass="33511" checksum="049F9AFB85CEB74F" modified="2017-02-15" version="1">MCFFFFLCIYLLNTVKALKSTNHPKKCLNILVSNEDIYKKKLLRRNLSLFRNGINFYFWKKKYHERSIEEKLNVIPVYILTNYNNSPYIFQENDKQVCYLFLCPHDAESMLNEITKNNSIKNISNIKIHSISMEKAYNLIKEFLLLKTMEKKNEDIKKNNIYWKLIPSKKQIQNALIFLSFKKKSDLIFPVFYVEGLYIHRDSKNIIPLFFDLEDLKKTIEEKFEKSSLKNYKIKVLNFVDLIFSFRIVTLKYNLLFIYLLPSFTFYTLSITYILFYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLA1</accession>
    <name>A0A1J1GLA1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Splicing factor Cactin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00080300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CACTIN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525921.1">
        <property type="nucleotide sequence ID" value="XM_028670477.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLA1"/>
    <dbReference type="GeneID" id="39729327"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00080300"/>
    <dbReference type="OMA" id="HIDFWND"/>
    <dbReference type="OrthoDB" id="265955at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019134">
        <property type="entry name" value="Cactin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018816">
        <property type="entry name" value="Cactin_central"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21737">
        <property type="entry name" value="POLYGLUTAMINE BINDING PROTEIN 1/MARVEL MEMBRANE-ASSOCIATING DOMAIN CONTAINING 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21737:SF4">
        <property type="entry name" value="SPLICING FACTOR CACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10312">
        <property type="entry name" value="Cactin_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09732">
        <property type="entry name" value="CactinC_cactus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01050">
        <property type="entry name" value="CactinC_cactus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Splicing factor cactin central" evidence="5">
        <location>
            <begin position="84"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Splicing factor Cactin C-terminal" evidence="4">
        <location>
            <begin position="425"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="58"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00034534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG93099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="542" mass="66132" checksum="F710856A4A194FB1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLG6</accession>
    <name>A0A1J1GLG6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cyclin-dependent kinase 2 homolog</fullName>
            <ecNumber evidence="2">2.7.11.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Cell division control protein 2 homolog</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">cdc2-related kinase 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">CRK1</name>
        <name evidence="16" type="ORF">PGAL8A_00091300</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">May form a complex composed of at least the catalytic subunit CRK2 and a cyclin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526031.1">
        <property type="nucleotide sequence ID" value="XM_028671699.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLG6"/>
    <dbReference type="GeneID" id="39729437"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00091300"/>
    <dbReference type="OMA" id="QDAMDFR"/>
    <dbReference type="OrthoDB" id="1732493at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007346">
        <property type="term" value="P:regulation of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07843">
        <property type="entry name" value="STKc_CDC2L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000738">
        <property type="entry name" value="Cdc2-related protein kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000054">
        <property type="entry name" value="Cyclin-dependent kinase 11B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045267">
        <property type="entry name" value="CDK11/PITSLRE_STKc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF107">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 11A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 16" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="498"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="23"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="234"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="325"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="437"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="25"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="71"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="236"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="450"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00039612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00042858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="CRG93209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="843" mass="99772" checksum="92B67C3D908BA380" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLG8</accession>
    <name>A0A1J1GLG8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00075900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525875.1">
        <property type="nucleotide sequence ID" value="XM_028675211.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLG8"/>
    <dbReference type="GeneID" id="39729284"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00075900"/>
    <dbReference type="OMA" id="RTMKIND"/>
    <dbReference type="OrthoDB" id="386801at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="8"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="100" mass="12109" checksum="3BDBAB8B068BE864" modified="2017-02-15" version="1">MIKDENLSLESMKKLKKLEEKLNEESQKKEKKKREENAINNYVKLKSLEHSLPQKIKKKIRTMKINDINDLKKLTVTKKKKYYIKILDKKDLKHKKKKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLH4</accession>
    <name>A0A1J1GLH4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00097800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526094.1">
        <property type="nucleotide sequence ID" value="XM_028672399.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLH4"/>
    <dbReference type="GeneID" id="39729502"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00097800"/>
    <dbReference type="OMA" id="IYMSSRV"/>
    <dbReference type="OrthoDB" id="361147at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="465"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="675"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="726"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="486"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="684"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="732"/>
            <end position="749"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="864" mass="104839" checksum="8408C16ECE6140B2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLI1</accession>
    <name>A0A1J1GLI1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00378200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000011">
        <property type="protein sequence ID" value="CRG93069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525891.1">
        <property type="nucleotide sequence ID" value="XM_028670144.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLI1"/>
    <dbReference type="GeneID" id="39732312"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00378200"/>
    <dbReference type="OrthoDB" id="6047286at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006496">
        <property type="entry name" value="CHP01606_Plasmodium_spp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09688">
        <property type="entry name" value="Wx5_PLAF3D7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="258" mass="30580" checksum="DF0B8D5D9D2E709C" modified="2017-02-15" version="1" fragment="single">MVLIAPYGFLWLFMGPNSTLWALWVLMAPCGSLWCPAGPNGTLWVLMVPYRFLWHPTGPNGTWENADIYKNPYNYWNEVTAPQMRKLFNDETSRMDPKWRDQKWNNDWNEISANHVKDLYSISHQQDISEEEKKKLIHSIMEKLMSEFLKFLDECEKEMRDYKIKSKCKNEMRDNKTKSESMKEIRDNKTESKGKNEMKDNKTESESKKEMIDNKTESESKNEMTDNKTESESKNDMTDNKTESEFKNEMTDNKTESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLL9</accession>
    <name>A0A1J1GLL9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MOLO1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00092300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526041.1">
        <property type="nucleotide sequence ID" value="XM_028671810.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLL9"/>
    <dbReference type="GeneID" id="39729447"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00092300"/>
    <dbReference type="OMA" id="YSYICDP"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005892">
        <property type="term" value="C:acetylcholine-gated channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033438">
        <property type="entry name" value="MOLO1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33748:SF5">
        <property type="entry name" value="GROUND-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33748">
        <property type="entry name" value="PROTEIN CBG04600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17175">
        <property type="entry name" value="MOLO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012000778" description="MOLO1 domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="267" mass="30601" checksum="D66119CC8DB6DC66" modified="2017-02-15" version="1">MNQNNIVSISFLFIVYYSVTHANVPIENPPFIFNNSKENGIKMFLDNQTPEDSLFKHSYSLDTTLENFPNPFIHPSLCNRNGLKYSYICDPNKILSRNTADKIEEILIYQRSNSSHYCIDKEVSYILGVALIKKLPYGVTADTFASQILEYWKLSNRNCNDGILLFFVKEDATFVLKWKKGAQSVINFRTATAMHKSFNQYIRRYSLEYSILRAVKLISEYLTEEIIPPTQTTQMVVALTIAIVVGLSYLACILIVFTDAQKVNKTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GM33</accession>
    <name>A0A1J1GM33_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Small nuclear ribonucleoprotein G</fullName>
            <shortName evidence="9">snRNP-G</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">SNRPG</name>
        <name evidence="11" type="ORF">PGAL8A_00115500</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Plays a role in pre-mRNA splicing.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000016">
        <property type="protein sequence ID" value="CRG93449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526271.1">
        <property type="nucleotide sequence ID" value="XM_028674365.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GM33"/>
    <dbReference type="GeneID" id="39729680"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00115500"/>
    <dbReference type="OMA" id="QENDIGM"/>
    <dbReference type="OrthoDB" id="274944at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043186">
        <property type="term" value="C:P granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034719">
        <property type="term" value="C:SMN-Sm protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097526">
        <property type="term" value="C:spliceosomal tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005689">
        <property type="term" value="C:U12-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005687">
        <property type="term" value="C:U4 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01719">
        <property type="entry name" value="Sm_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000061">
        <property type="entry name" value="Small nuclear ribonucleoprotein G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044641">
        <property type="entry name" value="Lsm7/SmG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034098">
        <property type="entry name" value="Sm_G"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10553">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10553:SF2">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9 11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Sm" evidence="10">
        <location>
            <begin position="9"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG93449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="83" mass="9509" checksum="A295C8581EDD563D" modified="2017-02-15" version="1">MTLTVGKAGPASDFRKFMEKRLQIYLNGNRQIVGILRGYDTFMNLVLDNTVEIKKDEQIEIGIVVIRGNSISYWECLDKVDVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMA6</accession>
    <name>A0A1J1GMA6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Diphthine--ammonia ligase</fullName>
            <ecNumber evidence="2">6.3.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Diphthamide synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Diphthamide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00123600</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>diphthine-[translation elongation factor 2] + NH4(+) + ATP = diphthamide-[translation elongation factor 2] + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19753"/>
            <dbReference type="Rhea" id="RHEA-COMP:10172"/>
            <dbReference type="Rhea" id="RHEA-COMP:10174"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16692"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:82696"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.1.14"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.14" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526351.1">
        <property type="nucleotide sequence ID" value="XM_028674751.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMA6"/>
    <dbReference type="GeneID" id="39729761"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00123600"/>
    <dbReference type="OMA" id="EVICHED"/>
    <dbReference type="OrthoDB" id="686384at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017178">
        <property type="term" value="F:diphthine-ammonia ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01994">
        <property type="entry name" value="AANH_PF0828-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000145">
        <property type="entry name" value="ATP-binding domain containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1490.10:FF:000001">
        <property type="entry name" value="Diphthine--ammonia ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1490.10">
        <property type="entry name" value="putative n-type atp pyrophosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002761">
        <property type="entry name" value="Diphthami_syn_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030662">
        <property type="entry name" value="DPH6/MJ0570"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00290">
        <property type="entry name" value="MJ0570_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12196:SF2">
        <property type="entry name" value="DIPHTHINE--AMMONIA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12196">
        <property type="entry name" value="DOMAIN OF UNKNOWN FUNCTION 71 DUF71 -CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01902">
        <property type="entry name" value="Diphthami_syn_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039123">
        <property type="entry name" value="Diphthamide_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Diphthamide synthase" evidence="10">
        <location>
            <begin position="1"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG93529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="249" mass="28437" checksum="0CBD80EDC7C05A46" modified="2017-02-15" version="1">MNVVGLISGGKDSLYNLVCCSKDGHNIITLAHLIPLKKQNETDSFMYQSAGFELIPSIAKCMEIPLIQHQIKREPINVDDLTYTYNSNDEVEDLYELLLEAKSKFPNINAVSCGAIISNYQKNRLEHVCKRLNLHVLTYLWGKNQKELLQNMISDGMDAIIVKIASFGLNKNHVGKTIKEIFNDLELVSEKYGLNICGEGGEYETITLDCSLYKYKIIIDEYEIIQHTYDVICPVFLLKPLKWKLEKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMA7</accession>
    <name>A0A1J1GMA7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Potassium channel, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PGAL8A_00128300</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>K(+)(in) = K(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29463"/>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526398.1">
        <property type="nucleotide sequence ID" value="XM_028674804.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729808"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00128300"/>
    <dbReference type="OrthoDB" id="433309at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005267">
        <property type="term" value="F:potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.70:FF:000146">
        <property type="entry name" value="Potassium channel, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047871">
        <property type="entry name" value="K_chnl_Slo-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10027">
        <property type="entry name" value="CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10027:SF10">
        <property type="entry name" value="SLOWPOKE 2, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22614">
        <property type="entry name" value="Slo-like_RCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10 16" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0631">Potassium channel</keyword>
    <keyword evidence="3" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="171"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="573"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="616"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="645"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="709"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="772"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="domain" description="Potassium channel" evidence="14">
        <location>
            <begin position="719"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="15">
        <location>
            <begin position="1528"/>
            <end position="1616"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1123"/>
            <end position="1226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="8"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1131"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1186"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1201"/>
            <end position="1224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF07885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF22614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="CRG93576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1881" mass="222343" checksum="567910DFDF22E71E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMT7</accession>
    <name>A0A1J1GMT7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Eukaryotic translation initiation factor 3 30 kDa subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00146600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526582.1">
        <property type="nucleotide sequence ID" value="XM_028675008.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMT7"/>
    <dbReference type="GeneID" id="39729990"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00146600"/>
    <dbReference type="OMA" id="WTEWLND"/>
    <dbReference type="OrthoDB" id="20381at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="201" mass="23503" checksum="5E0269AFE930021C" modified="2017-02-15" version="1">MEKDTMNNEVDNWMEWLDQDDEKREDIILDSTKDDIIKKNILQNNLDEIADFLDINENKKKNIENEKVGKTKTAEKIVTLESTPLNSIKDCETLGEILANRIKNCKAKSVSIERFLSIIIQACESKLNDIELQSIGKKIQLLIENRQKGKRYALINKKKPNEIKNSIKNYKDEVDMIYGDISYDEEDYDDDDEADKYFEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNW3</accession>
    <name>A0A1J1GNW3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptidase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00385000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526967.1">
        <property type="nucleotide sequence ID" value="XM_028670190.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732380"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00385000"/>
    <dbReference type="OMA" id="CEINVWN"/>
    <dbReference type="OrthoDB" id="76293at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147:SF22">
        <property type="entry name" value="ENDOPLASMIC RETICULUM METALLOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="METALLOPEPTIDASE M28 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="564"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="599"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="638"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="785"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="817"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="861"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="903"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="937"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M28" evidence="5">
        <location>
            <begin position="318"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG94146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1292" mass="153031" checksum="26CDDE5BD681455C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNY4</accession>
    <name>A0A1J1GNY4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00387400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526991.1">
        <property type="nucleotide sequence ID" value="XM_028670217.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNY4"/>
    <dbReference type="GeneID" id="39732404"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00387400"/>
    <dbReference type="OrthoDB" id="371165at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="378"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="735" mass="89350" checksum="C1A4E62D800576A1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNY9</accession>
    <name>A0A1J1GNY9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA topoisomerase VI, b subunit, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00172100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000020">
        <property type="protein sequence ID" value="CRG94014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526835.1">
        <property type="nucleotide sequence ID" value="XM_028670043.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNY9"/>
    <dbReference type="GeneID" id="39730248"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00172100"/>
    <dbReference type="OMA" id="HTFVQNF"/>
    <dbReference type="OrthoDB" id="1562195at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48444">
        <property type="entry name" value="DNA TOPOISOMERASE 6 SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48444:SF1">
        <property type="entry name" value="DNA TOPOISOMERASE 6 SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="499"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="503"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="518"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="544" mass="63863" checksum="F7AA9062199B536E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="40" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP63</accession>
    <name>A0A1J1GP63_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Vesicle-trafficking protein SEC22b</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">SEC22 vesicle-trafficking protein homolog B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="primary">SEC22</name>
        <name evidence="20" type="ORF">PGAL8A_00396200</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="13">Endoplasmic reticulum-Golgi intermediate compartment membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the synaptobrevin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527079.1">
        <property type="nucleotide sequence ID" value="XM_028670315.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP63"/>
    <dbReference type="GeneID" id="39732492"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00396200"/>
    <dbReference type="OMA" id="RKMAFAY"/>
    <dbReference type="OrthoDB" id="1719357at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033116">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14824">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15866">
        <property type="entry name" value="R-SNARE_SEC22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.50:FF:000016">
        <property type="entry name" value="Vesicle transporter Sec22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.50">
        <property type="entry name" value="Longin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010908">
        <property type="entry name" value="Longin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044565">
        <property type="entry name" value="Sec22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001388">
        <property type="entry name" value="Synaptobrevin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042855">
        <property type="entry name" value="V_SNARE_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45837">
        <property type="entry name" value="VESICLE-TRAFFICKING PROTEIN SEC22B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13774">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00957">
        <property type="entry name" value="Synaptobrevin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00219">
        <property type="entry name" value="SYNAPTOBREVN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01270">
        <property type="entry name" value="Longin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50859">
        <property type="entry name" value="LONGIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50892">
        <property type="entry name" value="V_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 16" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="12 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Longin" evidence="18">
        <location>
            <begin position="6"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="V-SNARE coiled-coil homology" evidence="19">
        <location>
            <begin position="139"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00024187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00024248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00033315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="CRG94258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="221" mass="26075" checksum="D56E413CF0FB3C69" modified="2017-02-15" version="1">MCDVVLLCRVSDGMTLVETNSETKNLSHKLELKKLCKKLESFPNLCTITSNQFNYHFLIENGIAYIAVFPITYPKKLAFLFLNDICKQFNEELMIQYGTHSIDYRSIIETIEKPYSFIKFDRKITKIKQEYKDPRSNIAIKKLNESLNEVSYIMKKNIDEILQRGENLEDVGRKAFNLKYESEKFKKVSRVLSLKHSLYQYGILFAILIFFLLIIIFKIYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP64</accession>
    <name>A0A1J1GP64_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nas2 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00398500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527102.1">
        <property type="nucleotide sequence ID" value="XM_028670340.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP64"/>
    <dbReference type="GeneID" id="39732515"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00398500"/>
    <dbReference type="OMA" id="HEYNCLE"/>
    <dbReference type="OrthoDB" id="72325at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070682">
        <property type="term" value="P:proteasome regulatory particle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040815">
        <property type="entry name" value="Nas2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035269">
        <property type="entry name" value="PSMD9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12651">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12651:SF1">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18265">
        <property type="entry name" value="Nas2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nas2 N-terminal" evidence="2">
        <location>
            <begin position="7"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="221" mass="26211" checksum="85B45B1A9E19EBBE" modified="2017-02-15" version="1">MDLKEFNELVKKRSEIENEINENLEFLEKPENKNIGMKGKLIDAEGFPRNDIDIYSIRVARNKIICLKNDYLDINKKIEEYLHKVHSTHPVIRVERNKNKNDEENLNWNKIYEDVNEVEIEHVKKNIFAIIDEMIDNSPSHKAGLKINDYIYQFGDVKKNENDDNENLDILKKISDYMKTNPSKIEIKVLREEKVYTYYIFPNKTHNGLYIGCHLTPIKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPB4</accession>
    <name>A0A1J1GPB4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AP-5 complex subunit sigma-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00384400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526961.1">
        <property type="nucleotide sequence ID" value="XM_028670183.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPB4"/>
    <dbReference type="GeneID" id="39732374"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00384400"/>
    <dbReference type="OMA" id="NIHLADY"/>
    <dbReference type="OrthoDB" id="370698at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030119">
        <property type="term" value="C:AP-type membrane coat adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005764">
        <property type="term" value="C:lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029392">
        <property type="entry name" value="AP-5_subunit_s1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16120">
        <property type="entry name" value="AP-5 COMPLEX SUBUNIT SIGMA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16120:SF0">
        <property type="entry name" value="AP-5 COMPLEX SUBUNIT SIGMA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15001">
        <property type="entry name" value="AP-5_subunit_s1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="207" mass="25216" checksum="823DCF7523F5D450" modified="2017-02-15" version="1">MVYGIIIHSSENETDFHFSYYYNGENEDEYKYIRQQSIIKRVIEENKYYEEDKGKSENISKRNTEKYLELFNIFLSKNANNEIKMDNEGIFRIVNPSLFKNKVNIMWKVLNKICYTLIFFTHENILLADYFLYNFIFVLREYYDKLKKFRKPDMNIFNPDEILAILYYFLPRGQLMLISFNQTKILYNKVKEFLENKAELPPKKRIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPI9</accession>
    <name>A0A1J1GPI9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PGAL8A_00405800</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the RING-type zinc finger family. LOG2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527175.1">
        <property type="nucleotide sequence ID" value="XM_028670420.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPI9"/>
    <dbReference type="GeneID" id="39732588"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00405800"/>
    <dbReference type="OMA" id="FCCKEEF"/>
    <dbReference type="OrthoDB" id="10261999at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16789">
        <property type="entry name" value="mRING-HC-C3HC5_MGRN1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045195">
        <property type="entry name" value="LOG2-like_mRING_C3HC5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045194">
        <property type="entry name" value="MGRN1/RNF157-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058981">
        <property type="entry name" value="MGRN1/RNF157-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22996">
        <property type="entry name" value="MAHOGUNIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22996:SF0">
        <property type="entry name" value="RE60872P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26192">
        <property type="entry name" value="RNF157-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0519">Myristate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="13">
        <location>
            <begin position="240"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG94354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="299" mass="34227" checksum="868252E813D8DBEA" modified="2017-02-15" version="1">MGIIGSSLANNQNDDFHNSPPRIISLNPSFNNRSANENLCDLISQGPNINIQKTSVVRNSINLRRKTLKLVNNGNNVYLINFIFDSLYDVELSIYFCCKEEISETQETLYIPTKYKTIKKIFHKEVNQVYISEPEDGIDLKNIDINDLKCKPSYEYIIPILIVLKSIGASIPQAQFNFAYIQENEIKENNNGEDKYKIVLYRQKIQFGNRSFEVQEIFGIEKSNEAQTDPVNNFLSGRECVICLSEERDTAILPCRHMCLCNLCANIVRMQNTKCPICRQAVRGLLQISIENNKVPNNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPJ0</accession>
    <name>A0A1J1GPJ0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00404500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527162.1">
        <property type="nucleotide sequence ID" value="XM_028670406.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPJ0"/>
    <dbReference type="GeneID" id="39732575"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00404500"/>
    <dbReference type="OMA" id="VIYENCE"/>
    <dbReference type="OrthoDB" id="371339at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="601"/>
            <end position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="632" mass="75328" checksum="18FAED2768818083" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPR7</accession>
    <name>A0A1J1GPR7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00399000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527107.1">
        <property type="nucleotide sequence ID" value="XM_028670346.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732520"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00399000"/>
    <dbReference type="OMA" id="NVHENTF"/>
    <dbReference type="OrthoDB" id="378101at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23160:SF3">
        <property type="entry name" value="SYNAPTONEMAL COMPLEX PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23160">
        <property type="entry name" value="SYNAPTONEMAL COMPLEX PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="619"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="2409"/>
            <end position="2429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="2600"/>
            <end position="2750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="2866"/>
            <end position="2890"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="121"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="335"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="856"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1011"/>
            <end position="1045"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1166"/>
            <end position="1364"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1392"/>
            <end position="1558"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1584"/>
            <end position="1663"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1750"/>
            <end position="1833"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="2034"/>
            <end position="2145"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="2177"/>
            <end position="2204"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="2510"/>
            <end position="2541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="624"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="2417"/>
            <end position="2429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="2631"/>
            <end position="2656"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="2664"/>
            <end position="2683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="2690"/>
            <end position="2702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="2710"/>
            <end position="2728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="2737"/>
            <end position="2750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="2866"/>
            <end position="2876"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2890" mass="345720" checksum="DD1E843C6F3B5C69" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPV2</accession>
    <name>A0A1J1GPV2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Leu/Phe-tRNA protein transferase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00403600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527153.1">
        <property type="nucleotide sequence ID" value="XM_028670396.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPV2"/>
    <dbReference type="GeneID" id="39732566"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00403600"/>
    <dbReference type="OMA" id="HENTWCV"/>
    <dbReference type="OrthoDB" id="2122564at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008914">
        <property type="term" value="F:leucyl-tRNA--protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.70:FF:000002">
        <property type="entry name" value="Leu/Phe-tRNA protein transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.70">
        <property type="entry name" value="Leucyl/phenylalanyl-tRNA-protein transferase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004616">
        <property type="entry name" value="Leu/Phe-tRNA_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042203">
        <property type="entry name" value="Leu/Phe-tRNA_Trfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30098">
        <property type="entry name" value="LEUCYL/PHENYLALANYL-TRNA--PROTEIN TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30098:SF2">
        <property type="entry name" value="LEUCYL_PHENYLALANYL-TRNA--PROTEIN TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03588">
        <property type="entry name" value="Leu_Phe_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="60"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="67"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG94332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="400" mass="47152" checksum="6216EC9CC2432B5B" modified="2017-02-15" version="1">MSTHENLKNDRNKLSDKIISDEIISDKIISDEIKSDEIKSDEIKSDEIISDEIKSEKVENKVIYSNEENKQRVEDKNNDEQDDIKKSDEKNEMKGDKRKTIKLDDDVNINKIIEKISKEEPQMLTKILNLMKNDNCLNFYPLLTPYHNIEKIVDILIEENYEYENTWCVHYDASFICQLFYEGFIPVASKQKVCKIENYETKIYKECLLIPKIHYIRSCMHPSEIHISKKVKKKCKNFYITIDKDFNGVMEGIVEKHGQNWLYPFVQKEFKRIFEKSVTYKNVQMHSVEVWYEDKLVAGEIGITVGSIYTSLTGFQRKNCAGTIQLCALAKLLEFQKFQLWDLGMLLPYKKEIGSKEIPMKEFFRKHRVFKFQNAEFKVPFKDKLNCSVLIKGTDNNDFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPZ1</accession>
    <name>A0A1J1GPZ1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00406200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527179.1">
        <property type="nucleotide sequence ID" value="XM_028670426.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPZ1"/>
    <dbReference type="GeneID" id="39732592"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00406200"/>
    <dbReference type="OMA" id="NDEHNQN"/>
    <dbReference type="OrthoDB" id="383784at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="291"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="321" mass="38498" checksum="672BCE81296650D9" modified="2017-02-15" version="1">MDKNSLKRRNRLLKKNESRMNILLGKSVDDNISQNNNNNDNLSNDKIYEQFSNNMSENIERKILNNVNNKKKIINENTDYEKNNNCVNMIDNNSNNFDYNKNVDNENYEDNEKQKNINDKIKNVKEDYLGSKKEILQEDVNFNHNENMSFNVIKDKNINYNSLKERSEFNINNMKKLHFSLLIILSILFSFIKLNYNNILLYNNIGKQFLYFIKSNNFFIYFSIIYNVIFLLFDIFLHCLKNNIRKKDLIENIKNVKKKLINESEFFLFIINNMLTVLTFLISIIKSYVVSIFLTYLFHDIFYNNIFYISSMNLNKKKHII</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ30</accession>
    <name>A0A1J1GQ30_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Surface-associated interspersed protein (SURFIN)</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00179300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527225.1">
        <property type="nucleotide sequence ID" value="XM_028670476.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ30"/>
    <dbReference type="GeneID" id="39730320"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00179300"/>
    <dbReference type="OMA" id="VGEWEHE"/>
    <dbReference type="OrthoDB" id="383264at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024288">
        <property type="entry name" value="SICA_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12879">
        <property type="entry name" value="SICA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Schizont-infected cell agglutination C-terminal" evidence="2">
        <location>
            <begin position="314"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="75"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="572" mass="71362" checksum="A9B7ECF8AAC197C3" modified="2017-02-15" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ43</accession>
    <name>A0A1J1GQ43_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Calmodulin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00203400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527452.1">
        <property type="nucleotide sequence ID" value="XM_028670728.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ43"/>
    <dbReference type="GeneID" id="39730560"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00203400"/>
    <dbReference type="OMA" id="WEFDENM"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016460">
        <property type="term" value="C:myosin II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050230">
        <property type="entry name" value="CALM/Myosin/TropC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048:SF0">
        <property type="entry name" value="CALMODULIN LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23048">
        <property type="entry name" value="MYOSIN LIGHT CHAIN 1, 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0007">Acetylation</keyword>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="43"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00020786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG94637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="207" mass="24923" checksum="EB8EA0A03972CF08" modified="2017-02-15" version="1">MNEKPYIPVIEKLNNEKNPNFYICGNGYIAPLDIKNLKKISNTEKKNLQRVFKMMDKDNTGKISVCNLHDILHKYNYKISKSEVERMIWEFDDNMDNCLDYDEIYFLYLRCVNDKKKQVPSDLYNIIQFFMFDYEMNGYITVEKTLQILYVRFGREKMDLEVQEIFGDKYEDESGVEKQIYLREYLDNEKKRIHKFKAESNKKGGKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ75</accession>
    <name>A0A1J1GQ75_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Gamete egress and sporozoite traversal protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00208200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527500.1">
        <property type="nucleotide sequence ID" value="XM_028670782.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ75"/>
    <dbReference type="GeneID" id="39730609"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00208200"/>
    <dbReference type="OMA" id="KSFVCYV"/>
    <dbReference type="OrthoDB" id="391223at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012227308" description="Gamete egress and sporozoite traversal protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="222"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="249" mass="29195" checksum="CA5E52BBC55F650A" modified="2017-02-15" version="1">MKLYIYYFGLFLTLALHLKAIQLHSVSYTPSAYIEIGDKISHRVGELWNNQFESFIDLVSKKIVDKLENNVSNDKISDKMMILLQNDAEIFDSHHYKDHNMALIQTIFFRKLKEKFNNSNFGKKIRELGSRAKSKIKSLYQKHKSKLQHFFNILMRSLVLPIAIKYIRKNIKKWKQKTLDATNKLDEDSKKIATPIINRLYENFGSKIDQYAEANSIDFEDEMQALDELAKDKKEIDALEKEEKAILKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQB8</accession>
    <name>A0A1J1GQB8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00203200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527450.1">
        <property type="nucleotide sequence ID" value="XM_028670726.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQB8"/>
    <dbReference type="GeneID" id="39730558"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00203200"/>
    <dbReference type="OrthoDB" id="371962at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="227" mass="28228" checksum="0FB1A7125F959F21" modified="2017-02-15" version="1">MQKFIDKVKLQNTQEDNSNNKRILNKKIYFDNLLNKKNKEVNKIEEDKILNVVKTYYQMKLKKKAFLIILNEYYRIQSILCVTKLNDTYRRWKIVFYIFLKNKYSCKIKKCVRESLGYIIEMHQRTNLKSHFFKILKNKIFNINKIYLKIKKKRVNKIMKNVFYKWFLLSMKSLNSKFEKAWDYYILRKKKRVFYLWKRLIDDENFFKNIDMTFFKLEKIASSWMEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQF3</accession>
    <name>A0A1J1GQF3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mitochondrial import inner membrane translocase subunit TIM50</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">TIM50</name>
        <name evidence="3" type="ORF">PGAL8A_00098000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the TIM23 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TIM50 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526096.1">
        <property type="nucleotide sequence ID" value="XM_028672422.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQF3"/>
    <dbReference type="GeneID" id="39729504"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00098000"/>
    <dbReference type="OrthoDB" id="445750at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005744">
        <property type="term" value="C:TIM23 mitochondrial import inner membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000139">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit TIM50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050365">
        <property type="entry name" value="TIM50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12210">
        <property type="entry name" value="DULLARD PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="1" id="KW-0653">Protein transport</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="1" id="KW-0811">Translocation</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="FCP1 homology" evidence="2">
        <location>
            <begin position="256"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU365079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="458" mass="54086" checksum="979E37DB7EA45777" modified="2017-02-15" version="1">MIKSLRNLVVHEKKIKGVLLRRNYIIKLFNSIDYRNKKINLYRLNKYLDLQNSKNDFMISKVNLFKGMNYPFNKWSENTSNENMLSKKSNISNYNEKMKNHTIIRNNINKIVNVEKSKSSNGINCNKLYVRNFSNISSNKNEQVKEEVLVSNVTKEKELNTTSKNNKTIKQMYIDKKQKEKMIKLYLLLSLILIPFGYTYMYCLQNNITIEDLLKIIKKNIELIETKYNDLLHEFIDKYFPLSNEPLLPDFKDLNYPENLPTLVIDLNYVIAKLEYNRKTGWRVLKRPYADLFFKELSSFYEIVIWSDDNFPVAQEVISRWGIPAIGCLHRDQCSKKKKFYVKDLKRLGRNLDRVVIIDHDSHAFMLQPENGILIKEFHGDVNDKEILCLIDLLKSFAISTYDIRQFLKKYGGGDYNIGKRYLQLKSDTEQKSKRIRNIGKIFHLDNKKTPNGISFNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQF5</accession>
    <name>A0A1J1GQF5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="5">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00204400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="5">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527463.1">
        <property type="nucleotide sequence ID" value="XM_028670740.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQF5"/>
    <dbReference type="GeneID" id="39730571"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00204400"/>
    <dbReference type="OMA" id="CICFITD"/>
    <dbReference type="OrthoDB" id="4310724at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="242"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="482"/>
            <end position="660"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="739" mass="86909" checksum="E7A960FF99ED9D6E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQG9</accession>
    <name>A0A1J1GQG9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutaminyl-peptide cyclotransferase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00206100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527479.1">
        <property type="nucleotide sequence ID" value="XM_028670759.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQG9"/>
    <dbReference type="GeneID" id="39730588"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00206100"/>
    <dbReference type="OMA" id="NDKLFQV"/>
    <dbReference type="OrthoDB" id="409395at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016603">
        <property type="term" value="F:glutaminyl-peptide cyclotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007788">
        <property type="entry name" value="QCT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31270">
        <property type="entry name" value="GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31270:SF1">
        <property type="entry name" value="GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05096">
        <property type="entry name" value="Glu_cyclase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="359" mass="41576" checksum="B54705D63BED0B27" modified="2017-02-15" version="1">MCLCRLVRKFVSLIILMVMLFLVAGILFTYYIIKNIKTSDIFSYVINTHTYEVLNKYKHIHDPSVGKEIKIDPKIETSSEKVHPFTQGFFFSDKNRLIESVGLYKSSFLREFDLVSGNTIRYTNFGPQYFGEGSAFIIEPSTYKKLILNLTYKEKTIFVFDYESLELYHTFTFDLDGYGLTSNVDTLQSVDALRKDNFVLNQKLWATTGDEYLYELQIPDDFKNSEKIYVSKKTKITCGGFIIDRTNELEYYAYSKTIFANIFLTNLIVEINSETGKCVKLINLDGLIKKCDNYEHIDENIDDVLNGIAISPQSKNEETPVLFVTGKNWSNIFEITIKRKIDELAHKVLLRGKFKLNLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQR6</accession>
    <name>A0A1J1GQR6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Inner membrane complex sub-compartment protein 3, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ISP3</name>
        <name evidence="2" type="ORF">PGAL8A_00220000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527618.1">
        <property type="nucleotide sequence ID" value="XM_028670913.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQR6"/>
    <dbReference type="GeneID" id="39730727"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00220000"/>
    <dbReference type="OMA" id="HRNSCES"/>
    <dbReference type="OrthoDB" id="345393at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041296">
        <property type="entry name" value="ISP3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18045">
        <property type="entry name" value="ISP3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ISP3 C-terminal" evidence="1">
        <location>
            <begin position="36"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="150" mass="17260" checksum="D864BB2F4FD1130F" modified="2017-02-15" version="1">MGNTLCCIHDLKNNKSNIDIIKSDNEIYGDYGDWTLEGWIDKYEKGDVIKVAFPDGNEIQCHLKIYLKEKCFELSLDNKVRVINFNDINCILNRNNCESLLESEKNLLKSPKVIGIRLISTLKAIAFAMDSPGEARMFTEFIEKYCLNEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQV4</accession>
    <name>A0A1J1GQV4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphatase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00224000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527658.1">
        <property type="nucleotide sequence ID" value="XM_028670957.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730767"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00224000"/>
    <dbReference type="OrthoDB" id="411211at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051558">
        <property type="entry name" value="Metallophosphoesterase_PAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10161">
        <property type="entry name" value="TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10161:SF14">
        <property type="entry name" value="TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="5">
        <location>
            <begin position="643"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="284"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1032"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1113"/>
            <end position="1192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="284"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1113"/>
            <end position="1136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1137"/>
            <end position="1189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG94843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1328" mass="157524" checksum="A2BB036DECA2A21C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQX8</accession>
    <name>A0A1J1GQX8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Mitochondrial ribosomal protein S14, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00206500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527483.1">
        <property type="nucleotide sequence ID" value="XM_028670763.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQX8"/>
    <dbReference type="GeneID" id="39730592"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00206500"/>
    <dbReference type="OMA" id="RFTRMSK"/>
    <dbReference type="OrthoDB" id="413436at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="112" mass="13311" checksum="1AA291D7279E3960" modified="2017-02-15" version="1">MAARNPGPYLNQVPLGFPSYNRRVFRDILARRAFMESEVNTRIYKNIFENLGFKGQIRINNKVGVNRIRMRCIQGGYSRGIYKFTRMAKMAFFQTAREGWLKKYGYRPDLFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR83</accession>
    <name>A0A1J1GR83_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Aminodeoxychorismate lyase, putative</fullName>
            <ecNumber evidence="1">4.1.3.38</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ADCL</name>
        <name evidence="1" type="ORF">PGAL8A_00217700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.38" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527595.1">
        <property type="nucleotide sequence ID" value="XM_028670887.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR83"/>
    <dbReference type="GeneID" id="39730704"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00217700"/>
    <dbReference type="OMA" id="EYIFNFT"/>
    <dbReference type="OrthoDB" id="59470at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008696">
        <property type="term" value="F:4-amino-4-deoxychorismate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="entry name" value="D-amino Acid Aminotransferase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47703">
        <property type="entry name" value="D-AMINOACID AMINOTRANSFERASE-LIKE PLP-DEPENDENT ENZYMES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47703:SF2">
        <property type="entry name" value="D-AMINOACID AMINOTRANSFERASE-LIKE PLP-DEPENDENT ENZYMES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="D-aminoacid aminotransferase-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="316" mass="37473" checksum="4986FC322B5E1DA5" modified="2017-02-15" version="1">MAILIKENIPSLVDMSIQDFIKLGINGVYTTMKTVLSHEYIFNLTLHMKNLCKYTTEFLNLQRTKDNEEYISKILKCVTVENIRKHCCENIKKAFEFLNNLNDDLKRKYFNENSDYMIIVTVMWETENNNISLNRNYSILCFIKSLPCHPNNIQIDIMYGQRKLPNIKYTDVFEIKDKLLKMKCPDSHEIVLYNDKHEITEGLTCNFFCFFNDTLYTSKDELVLNGTIRKEIIDLCEKEGVKLKKDSINIKDIEYFEFCFICSTTRNILPIKKIILFSDNKKTFEKNVNHPILIHLQKKLQEIIEKKKEKYDVYIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRC0</accession>
    <name>A0A1J1GRC0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AMMECR1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00245600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527870.1">
        <property type="nucleotide sequence ID" value="XM_028671193.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRC0"/>
    <dbReference type="GeneID" id="39730984"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00245600"/>
    <dbReference type="OMA" id="LFITWNK"/>
    <dbReference type="OrthoDB" id="24630at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.700.20">
        <property type="entry name" value="Hypothetical protein ph0010, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023473">
        <property type="entry name" value="AMMECR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036071">
        <property type="entry name" value="AMMECR1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002733">
        <property type="entry name" value="AMMECR1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027485">
        <property type="entry name" value="AMMECR1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13016:SF0">
        <property type="entry name" value="AMME SYNDROME CANDIDATE GENE 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13016">
        <property type="entry name" value="AMMECR1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01871">
        <property type="entry name" value="AMMECR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143447">
        <property type="entry name" value="AMMECR1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51112">
        <property type="entry name" value="AMMECR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMMECR1" evidence="1">
        <location>
            <begin position="18"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="231" mass="27433" checksum="CF7E7A3DD9CAE657" modified="2017-02-15" version="1">MNSSNLDEDDVNLNDEDIVSELVEKKDIICSWCFDILKHELKNEKFDYVPPILKKLHKKGVKIPFFVKWMKLIDIKDLGSYNCDLYDLKGCIGCLNDIDILQLYYYTLQSALNDTRFYPITLKDLPYLKVTITYLFNFEKCNHIYDWIIGKHGIKINFTINRKKYSSTFLPDVALQHNFDHKMTIRKLIRKANYKGEINDELLEKIQVERYEGISCSLTYQDYEKLKFSYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRF8</accession>
    <name>A0A1J1GRF8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L18a</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00252300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527932.1">
        <property type="nucleotide sequence ID" value="XM_028671262.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRF8"/>
    <dbReference type="GeneID" id="39731051"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00252300"/>
    <dbReference type="OMA" id="CIFAKND"/>
    <dbReference type="OrthoDB" id="1294322at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.10:FF:000001">
        <property type="entry name" value="60S ribosomal protein L18a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L18a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00273">
        <property type="entry name" value="Ribosomal_eL20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028877">
        <property type="entry name" value="Ribosomal_eL20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023573">
        <property type="entry name" value="Ribosomal_eL20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021138">
        <property type="entry name" value="Ribosomal_eL20_eukaryotes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10052">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L18A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01775">
        <property type="entry name" value="Ribosomal_L18A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002190">
        <property type="entry name" value="Ribosomal_L18a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160374">
        <property type="entry name" value="RplX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein eL20" evidence="5">
        <location>
            <begin position="13"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR002190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG95119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="184" mass="21811" checksum="AEAFC6F1830A828F" modified="2017-02-15" version="1">MVKTIDKSVTTNIKQYHIVGRAIPTEKDKNPNVYRMCIFAKNETNAKSRFWYFMKKINKLKKSNGEILACEIIRERFPLRVKNYGVLLRYDSRTGTHNMYKEFRDTTKEGAISQLYSEMAGRHRARASSISIIRISEISSNLVRRPHIRQLLRKKLRFPALHLPTLKREFRKKYAAKRPSTYRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRH9</accession>
    <name>A0A1J1GRH9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Rab GTPase activator, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00227300</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Synapse</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527691.1">
        <property type="nucleotide sequence ID" value="XM_028670994.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730800"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00227300"/>
    <dbReference type="OMA" id="LNDNGKH"/>
    <dbReference type="OrthoDB" id="26679at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030659">
        <property type="term" value="C:cytoplasmic vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006571">
        <property type="entry name" value="TLDc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23354:SF122">
        <property type="entry name" value="GTPASE-ACTIVATING PROTEIN SKYWALKER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23354">
        <property type="entry name" value="NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07534">
        <property type="entry name" value="TLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00584">
        <property type="entry name" value="TLDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51886">
        <property type="entry name" value="TLDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0770">Synapse</keyword>
    <feature type="domain" description="TLDc" evidence="8">
        <location>
            <begin position="1320"/>
            <end position="1483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="386"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="938"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1015"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="386"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="407"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1015"/>
            <end position="1034"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1483" mass="175682" checksum="81B7C012B65E8662" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRL5</accession>
    <name>A0A1J1GRL5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Calpain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00231400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527731.1">
        <property type="nucleotide sequence ID" value="XM_028671038.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730841"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00231400"/>
    <dbReference type="OMA" id="CFVRKIG"/>
    <dbReference type="OrthoDB" id="9374162at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="665"/>
            <end position="699"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1772" mass="213322" checksum="7A4CB91C696C8DE2" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRP3</accession>
    <name>A0A1J1GRP3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">CPW-WPC family protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00249800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527911.1">
        <property type="nucleotide sequence ID" value="XM_028671239.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRP3"/>
    <dbReference type="GeneID" id="39731026"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00249800"/>
    <dbReference type="OMA" id="NYYLKFC"/>
    <dbReference type="OrthoDB" id="368768at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006387">
        <property type="entry name" value="CPW_WPC_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01492">
        <property type="entry name" value="CPW_WPC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09717">
        <property type="entry name" value="CPW_WPC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01099">
        <property type="entry name" value="CPW_WPC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012227314" evidence="2">
        <location>
            <begin position="22"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="CPW-WPC" evidence="3">
        <location>
            <begin position="187"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="CPW-WPC" evidence="3">
        <location>
            <begin position="249"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="CPW-WPC" evidence="3">
        <location>
            <begin position="313"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="CPW-WPC" evidence="3">
        <location>
            <begin position="376"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="CPW-WPC" evidence="3">
        <location>
            <begin position="442"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="538" mass="62381" checksum="8BD1D8FACCB851D1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRS8</accession>
    <name>A0A1J1GRS8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00240100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527817.1">
        <property type="nucleotide sequence ID" value="XM_028671135.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRS8"/>
    <dbReference type="GeneID" id="39730929"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00240100"/>
    <dbReference type="OrthoDB" id="391033at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="124" mass="14966" checksum="35F917676B8DD02B" modified="2017-02-15" version="1">MNFDDFVHIIYGKNVFHDDENIEYIRDFIFPFLIPLVRSVNQEKEKHKYFKIVYDCGDKKKINNLCCEKNDTNIDHVNIFDTDKLEEKPTVLFEIQQEILTKYVKTNPILLLSQYLEEECRKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS24</accession>
    <name>A0A1J1GS24_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nuclear migration protein nudC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Nuclear distribution protein C homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">NUDC</name>
        <name evidence="9" type="ORF">PGAL8A_00247700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nudC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527891.1">
        <property type="nucleotide sequence ID" value="XM_028671217.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS24"/>
    <dbReference type="GeneID" id="39731005"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00247700"/>
    <dbReference type="OMA" id="TMEWWAT"/>
    <dbReference type="OrthoDB" id="416217at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06467">
        <property type="entry name" value="p23_NUDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.790:FF:000001">
        <property type="entry name" value="Nuclear migration protein nudC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037898">
        <property type="entry name" value="NudC_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025934">
        <property type="entry name" value="NudC_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12356:SF3">
        <property type="entry name" value="NUCLEAR MIGRATION PROTEIN NUDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12356">
        <property type="entry name" value="NUCLEAR MOVEMENT PROTEIN NUDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14050">
        <property type="entry name" value="Nudc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="8">
        <location>
            <begin position="147"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="84"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="94"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG95078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="320" mass="37735" checksum="AB482B51B7A9A191" modified="2017-02-15" version="1">MDPNAINEKFDFFMLNFARECGDINNLLNHFFYFLLRKTDFILKSKNLEQCEEIVLKNLRKQYAKKEKYMAELKKEQIKESECKENTVNSNLKKNKETEKNDNKVKDEKKNTKINENKQKNDDNKKEKKKSNSADSDDSLPPKDNGGITDKYRWIQTTSSLEMFIDAKEKIKTKDIKVDITYKKLFVKIKDKVIIDGEFYKKIKPEGSIWTLEDNQIIHILIEKLHTMEWWATAIKGDAEIDVKKIVPENSRMDDLDPETRAVVEKMLYDQRQKSLNLPTSDEQKKYEIFEKFKKMHPELDFSNANINFGNSSNNIFSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS27</accession>
    <name>A0A1J1GS27_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00004400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528090.1">
        <property type="nucleotide sequence ID" value="XM_028671438.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728566"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00004400"/>
    <dbReference type="OMA" id="FKMYFMH"/>
    <dbReference type="OrthoDB" id="387337at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13595">
        <property type="entry name" value="ARL6IP4 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13595:SF3">
        <property type="entry name" value="CXC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1464"/>
            <end position="1482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1494"/>
            <end position="1512"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1532"/>
            <end position="1554"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1749"/>
            <end position="1767"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="2206"/>
            <end position="2226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="2555"/>
            <end position="2573"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="2708"/>
            <end position="2730"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="2742"/>
            <end position="2760"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="685"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="739"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="860"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="938"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1085"/>
            <end position="1158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1171"/>
            <end position="1278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2830"/>
            <end position="2879"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2894"/>
            <end position="2924"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3670"/>
            <end position="3695"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2599"/>
            <end position="2626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="685"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="701"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="739"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="860"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="874"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="940"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="964"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1086"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1103"/>
            <end position="1148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1171"/>
            <end position="1201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1207"/>
            <end position="1220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1235"/>
            <end position="1278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="2833"/>
            <end position="2862"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2863"/>
            <end position="2879"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2897"/>
            <end position="2924"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="3675"/>
            <end position="3695"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3763" mass="450026" checksum="41FB93784C1B1381" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSA3</accession>
    <name>A0A1J1GSA3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00014600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528188.1">
        <property type="nucleotide sequence ID" value="XM_028671547.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSA3"/>
    <dbReference type="GeneID" id="39728668"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00014600"/>
    <dbReference type="OMA" id="FYPYELK"/>
    <dbReference type="OrthoDB" id="371808at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="558"/>
            <end position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1234" mass="149960" checksum="86D6328C37877D45" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSD2</accession>
    <name>A0A1J1GSD2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Serine repeat antigen, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00017000</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528212.1">
        <property type="nucleotide sequence ID" value="XM_028671573.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSD2"/>
    <dbReference type="GeneID" id="39728692"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00017000"/>
    <dbReference type="OMA" id="DCGLCWI"/>
    <dbReference type="OrthoDB" id="10253408at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02619">
        <property type="entry name" value="Peptidase_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000169">
        <property type="entry name" value="Pept_cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013128">
        <property type="entry name" value="Peptidase_C1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000668">
        <property type="entry name" value="Peptidase_C1A_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12411">
        <property type="entry name" value="CYSTEINE PROTEASE FAMILY C1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00112">
        <property type="entry name" value="Peptidase_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00705">
        <property type="entry name" value="PAPAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00645">
        <property type="entry name" value="Pept_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00139">
        <property type="entry name" value="THIOL_PROTEASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013153649" evidence="7">
        <location>
            <begin position="17"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C1A papain C-terminal" evidence="8">
        <location>
            <begin position="524"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="38"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="819"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG95401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="957" mass="108648" checksum="E83ED08AE74A2F36" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSF3</accession>
    <name>A0A1J1GSF3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">RuvB-like helicase</fullName>
            <ecNumber evidence="12">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PGAL8A_00168600</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16 17">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the RuvB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="12"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526800.1">
        <property type="nucleotide sequence ID" value="XM_028670005.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSF3"/>
    <dbReference type="GeneID" id="39730213"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00168600"/>
    <dbReference type="OMA" id="IINTEPY"/>
    <dbReference type="OrthoDB" id="10060499at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002221">
        <property type="entry name" value="RuvB-like 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000010">
        <property type="entry name" value="RuvB-like helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.360:FF:000002">
        <property type="entry name" value="RuvB-like helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.360">
        <property type="entry name" value="RuvB-like helicase, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027238">
        <property type="entry name" value="RuvB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041048">
        <property type="entry name" value="RuvB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042487">
        <property type="entry name" value="RuvBL1/2_DNA/RNA_bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010339">
        <property type="entry name" value="TIP49_P-loop"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11093">
        <property type="entry name" value="RUVB-RELATED REPTIN AND PONTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06068">
        <property type="entry name" value="TIP49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17856">
        <property type="entry name" value="TIP49_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0804">Transcription</keyword>
    <keyword evidence="8 12" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="13">
        <location>
            <begin position="62"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG93979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="482" mass="54509" checksum="C6B9FD9B82F8D084" modified="2017-02-15" version="1">MKLEEVKDIQKIERIGAHSHIRGLGLNDCLDARYCSEGMIGQMSARKAAGIVLRMIKEGRISGRAILLAGQPGTGKTAIAMGIAKALGEDTPFTHISGSEVYSLEMSKTEALTQAFRRSIGVRVKEESEVIEGEVVEIEIEKYNESDINNSNRKVGKMILKTTEMETLYDLGNKMIDALQKENITAGDVISIDKSTGKITKIGKSFARSKDYDAMDPNTNFVQCPEGELQKRKEVVHTVTLHDIDAINSRTQGFLALFSGDTGEIKNEIREHIDMKISEWQEDEKAEIVPGVLFIDEVHMLDIECFSYLNRALESEQSPIVIMATNRGITHIRGTDYKAPHGIPLDLLDRTLIIPTYPYKHQDILKILEQRAEEEDVEIDEYAKELLCKIASESSLRYALHLITLANLVSKKRKATEVTVQDVRRVYNLFIDVKRSTQYLIEYQNEFMFSELPKEDECVKEEVCEEKREIQEKQSVNSNISN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSM0</accession>
    <name>A0A1J1GSM0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00005900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528105.1">
        <property type="nucleotide sequence ID" value="XM_028671454.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSM0"/>
    <dbReference type="GeneID" id="39728581"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00005900"/>
    <dbReference type="OMA" id="WLFGNPF"/>
    <dbReference type="OrthoDB" id="409619at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="85" mass="10128" checksum="437B782024078A1C" modified="2017-02-15" version="1">MTSAPGLAFANLTLMLDVPQLPAIFFVNIRNNFKVFMNEIKQKIIEHEEIYYPHNRINLQNKRINKMGRIRKYSNNNNWLFGNPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GST9</accession>
    <name>A0A1J1GST9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">U1 small nuclear ribonucleoprotein C, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00274200</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528354.1">
        <property type="nucleotide sequence ID" value="XM_028671730.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GST9"/>
    <dbReference type="GeneID" id="39731274"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00274200"/>
    <dbReference type="OrthoDB" id="191651at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000690">
        <property type="entry name" value="Matrin/U1-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040023">
        <property type="entry name" value="WBP4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13173">
        <property type="entry name" value="WW DOMAIN BINDING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13173:SF10">
        <property type="entry name" value="WW DOMAIN-BINDING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50171">
        <property type="entry name" value="ZF_MATRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Matrin-type" evidence="8">
        <location>
            <begin position="11"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="290"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="419"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="44"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="290"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="419"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG95545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="553" mass="66706" checksum="3BBA474E9AD08D4E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSY9</accession>
    <name>A0A1J1GSY9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00279100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528402.1">
        <property type="nucleotide sequence ID" value="XM_028671784.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSY9"/>
    <dbReference type="GeneID" id="39731324"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00279100"/>
    <dbReference type="OMA" id="CEIEAYC"/>
    <dbReference type="OrthoDB" id="361164at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15841">
        <property type="entry name" value="SNARE_Qc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="2">
        <location>
            <begin position="186"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="286" mass="33747" checksum="CB85FEFD2BCEF063" modified="2017-02-15" version="1">MTKKKKDDNESNKTDLEDIKKKLEELKSKTEIPDVKLGIVAKNVDPFNDLKLHILNILDETRKCIREKENTQKFYGNNMEVIKRGNIIYNNMKNVDVYFTKLEEILNKQLKQKHLFNQEELCDKNETFDLLKKQIYECKKLSNYNEIKYAAPMDFNEFKNKPNLERKEMSDITHDEDDLIIINRWKERDKQFNEEILQIGEVIDKIGDNAVTITQKAEQQNEIILNLQDQTDKAHDNVKEANIEIKKVMIKQTQATWCCRISLIITLLILIVLTLSIISNKFIKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSZ8</accession>
    <name>A0A1J1GSZ8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">60S ribosomal protein L10, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00285900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528470.1">
        <property type="nucleotide sequence ID" value="XM_028671859.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSZ8"/>
    <dbReference type="GeneID" id="39731392"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00285900"/>
    <dbReference type="OMA" id="GNHEIYR"/>
    <dbReference type="OrthoDB" id="10258869at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01433">
        <property type="entry name" value="Ribosomal_L16_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1170.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.300:FF:000003">
        <property type="entry name" value="60S ribosomal protein L10, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.10">
        <property type="entry name" value="Ribosomal protein L10e/L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047873">
        <property type="entry name" value="Ribosomal_uL16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018255">
        <property type="entry name" value="Ribosomal_uL16_CS_euk_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016180">
        <property type="entry name" value="Ribosomal_uL16_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001197">
        <property type="entry name" value="Ribosomal_uL16_euk_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036920">
        <property type="entry name" value="Ribosomal_uL16_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003239">
        <property type="entry name" value="PRK04199.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00279">
        <property type="entry name" value="uL16_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11726">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00252">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005590">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54686">
        <property type="entry name" value="Ribosomal protein L16p/L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01257">
        <property type="entry name" value="RIBOSOMAL_L10E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG95662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="219" mass="25269" checksum="54A40C2CCA206990" modified="2017-02-15" version="1">MGRRPARCYRYCKNKPYPKSRYCRGVPDPKIRIYDMGKKKADVNEFSGVVHLVSYEYEQISSEALEAARICANKYMITNCGKDNFHLRIRVHPFHVLRINKMLSCAGADRLQTGMRGAFGKPNGVVARVDIGQVLLSIRTKENFVPKAAEALRRAKYKFPGRQKVFISNKWGFTKFSKDEYQEYKKKGRIISDGVNCKFIREKGPLENIYKDINTIIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTA2</accession>
    <name>A0A1J1GTA2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine/threonine protein phosphatase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00192400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000029">
        <property type="protein sequence ID" value="CRG94526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527341.1">
        <property type="nucleotide sequence ID" value="XM_028670605.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTA2"/>
    <dbReference type="GeneID" id="39730449"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00192400"/>
    <dbReference type="OrthoDB" id="10331477at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF827">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="1">
        <location>
            <begin position="189"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="507" mass="59186" checksum="70E75FE018475BD8" modified="2017-02-15" version="1">MKHLLNAIKVIKDCCTRREELEESNYKQLLDLLPLSESYEIVNERNLHILKKDIPLSNIKLKLFDKNKNRQNILNTNVKITEESWKKEDSENESFIKNRHEDLLYKKKKLNSSIIQENFLYDIDKNNENCSNSIIKENVIKNLKEKEVSSNIYCAHGKLSDRNAVEKNFKLKKIEIIPKFEKKENIMNSFSVVCMRGNQNEYYKSKNNNDYIYFNNYEQYFFIQAYELKIAGIISGTGKNSVSVCDNIVFHLLKTILRNLKNVYENKRNIWLSDQIEYILLSSINDTNNYIKINLQESFNSGCSLCVCAYSKKHELLTILNIGNIQTILVKNIDGKKKEDTKNHHISNALYETILITKKHDVLNKEEKERILSYGCIINDDSENENKNTWKNIDYLNKFNEKNDLKTLNITKAIGLFNFSNYGLSNIPDIIDIKLNIHTSGFLILVSHTISQVYNSHNLVEFLFNKSNNNSLFESSKKLIHNVHSVYMSTENSNIKDMTIIILPLID</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTZ9</accession>
    <name>A0A1J1GTZ9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoenolpyruvate carboxylase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00298100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528577.1">
        <property type="nucleotide sequence ID" value="XM_028671979.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTZ9"/>
    <dbReference type="GeneID" id="39731514"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00298100"/>
    <dbReference type="OMA" id="VFGWTQS"/>
    <dbReference type="OrthoDB" id="1365747at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008964">
        <property type="term" value="F:phosphoenolpyruvate carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015977">
        <property type="term" value="P:carbon fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.90">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021135">
        <property type="entry name" value="PEP_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033129">
        <property type="entry name" value="PEPCASE_His_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30523">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30523:SF6">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00311">
        <property type="entry name" value="PEPcase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00150">
        <property type="entry name" value="PEPCARBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00393">
        <property type="entry name" value="PEPCASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="1">
        <location>
            <position position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1129" mass="131334" checksum="A9920E59EB7E1E52" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU71</accession>
    <name>A0A1J1GU71_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00329500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528886.1">
        <property type="nucleotide sequence ID" value="XM_028672323.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU71"/>
    <dbReference type="GeneID" id="39731824"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00329500"/>
    <dbReference type="OrthoDB" id="387225at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="286" mass="35826" checksum="6694A0E6FE41FBCF" modified="2017-02-15" version="1">MTFYNDKGRKLPRTLSFSDMYTLVFFINYLRNKNEAFKRINLVNSKFYRLYSILFIISLYFLLQRISKRKDKTCLGLYFNNLNLRELSEQLSKEYRESVEDFPCLRLYFNKLNLRESTEHLSKECRKYYLESSESMYAKRKIYELDLFPDIETDEEKSKRLKEIWYKNCLKERASYWQKRMKYWNEIEENIYIDWYFGPKTKKMDKEWKDKKWNEWFEMFSKKMWKEDMKDTKSFKKKIKREYSLEVIVQSFMKKEKSFEKKKIKIMKEWDEFVNISVEQWENEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU91</accession>
    <name>A0A1J1GU91_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Reticulocyte binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00329300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528884.1">
        <property type="nucleotide sequence ID" value="XM_028672320.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731822"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00329300"/>
    <dbReference type="OMA" id="YQRDMRC"/>
    <dbReference type="OrthoDB" id="386780at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012227313" evidence="2">
        <location>
            <begin position="20"/>
            <end position="2674"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="585"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="666"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="954"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1095"/>
            <end position="1122"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1240"/>
            <end position="1310"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1350"/>
            <end position="1384"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1551"/>
            <end position="1578"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1660"/>
            <end position="1694"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1779"/>
            <end position="1816"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1918"/>
            <end position="1986"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2427"/>
            <end position="2463"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2508"/>
            <end position="2592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2674" mass="313137" checksum="87B12B6F9B03AC85" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUB5</accession>
    <name>A0A1J1GUB5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Polyubiquitin, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00310100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528697.1">
        <property type="nucleotide sequence ID" value="XM_028672112.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUB5"/>
    <dbReference type="GeneID" id="39731634"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00310100"/>
    <dbReference type="OMA" id="GGRGCYP"/>
    <dbReference type="OrthoDB" id="428577at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd01803">
        <property type="entry name" value="Ubl_ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000158">
        <property type="entry name" value="Polyubiquitin 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019954">
        <property type="entry name" value="Ubiquitin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00299">
        <property type="entry name" value="UBIQUITIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="7">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="77" mass="8698" checksum="1CB59A35397EFC9B" modified="2017-02-15" version="1">MQIFVKTLTGKTITLDVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUF0</accession>
    <name>A0A1J1GUF0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Calponin-homology (CH) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00207000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527488.1">
        <property type="nucleotide sequence ID" value="XM_028670769.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730597"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00207000"/>
    <dbReference type="OMA" id="LTYIFWQ"/>
    <dbReference type="OrthoDB" id="2021149at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42180:SF4">
        <property type="entry name" value="CALPONIN-HOMOLOGY (CH) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42180">
        <property type="entry name" value="HOMOLOGY DOMAIN-CONTAINING PROTEIN,PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="2">
        <location>
            <begin position="6"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="706"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1132"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1459"/>
            <end position="1528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1671" mass="199293" checksum="7C732E675D735E80" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUQ2</accession>
    <name>A0A1J1GUQ2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA (guanine(9)-N(1))-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.221</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00345700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>guanosine(9) in tRNA + S-adenosyl-L-methionine = N(1)-methylguanosine(9) in tRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:43156"/>
            <dbReference type="Rhea" id="RHEA-COMP:10367"/>
            <dbReference type="Rhea" id="RHEA-COMP:10368"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="EC" id="2.1.1.221"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.221" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529044.1">
        <property type="nucleotide sequence ID" value="XM_028672497.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUQ2"/>
    <dbReference type="GeneID" id="39731987"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00345700"/>
    <dbReference type="OMA" id="FKKNDGW"/>
    <dbReference type="OrthoDB" id="278300at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052905">
        <property type="term" value="F:tRNA (guanosine(9)-N1)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002939">
        <property type="term" value="P:tRNA N1-guanine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18089">
        <property type="entry name" value="SPOUT_Trm10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028564">
        <property type="entry name" value="MT_TRM10-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038459">
        <property type="entry name" value="MT_TRM10-typ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007356">
        <property type="entry name" value="tRNA_m1G_MeTrfase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13563">
        <property type="entry name" value="TRNA (GUANINE-9-) METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13563:SF13">
        <property type="entry name" value="TRNA METHYLTRANSFERASE 10 HOMOLOG A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51675">
        <property type="entry name" value="SAM_MT_TRM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM-dependent MTase TRM10-type" evidence="7">
        <location>
            <begin position="103"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="33"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="33"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="52"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG96239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="347" mass="42231" checksum="B114483C127DEE3B" modified="2017-02-15" version="1">MLREEYIENNEEINDFFYNLSNVIDENDIKKLDKNRKTKREKKKDKRELLKEKRKKNRPEEKKRKKNKRKEELLKILNDMNEEEKIAYLKERKILEKKMKEKKREFLLESFTMGYKICFNCNFQNYMEEKEISSLAKQIFLSYHYMTKNNIPIQFHFTSLNNNDSLFSYLKKYSINKWKVHKHTENYWDIFSKEKIVVLSPDAIEELEEVKKDEVYIIAALVDRSVSKNLSFYEASSYGFVTKKLPLEKYIKKKKSNVLNVNTVVEILINYIKIKNWKKVFEICIPQKKVLCFCHELSQNENKNINIYNNKYEYESENENMDRNLIQNINECNNKDIHENIYENMKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUQ7</accession>
    <name>A0A1J1GUQ7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein PET117</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00217400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527592.1">
        <property type="nucleotide sequence ID" value="XM_028670884.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUQ7"/>
    <dbReference type="GeneID" id="39730701"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00217400"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031568">
        <property type="entry name" value="Pet117"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15786">
        <property type="entry name" value="PET117"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="29"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="58" mass="7051" checksum="7E7B71AC39131E45" modified="2017-02-15" version="1">MKRFSGQILLISTCILSVGVYYYVKTTKYSDYRRRYEGVLNDIERQKKKIEKWKVKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVD7</accession>
    <name>A0A1J1GVD7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00371200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529292.1">
        <property type="nucleotide sequence ID" value="XM_028672773.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVD7"/>
    <dbReference type="GeneID" id="39732242"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00371200"/>
    <dbReference type="OMA" id="NYYNYVR"/>
    <dbReference type="OrthoDB" id="377382at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="760" mass="91532" checksum="8445DE0DE1A63FE1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVE5</accession>
    <name>A0A1J1GVE5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">CDPK6</name>
        <name evidence="18" type="ORF">PGAL8A_00349400</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529081.1">
        <property type="nucleotide sequence ID" value="XM_028672539.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732024"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00349400"/>
    <dbReference type="OMA" id="EYHIDAC"/>
    <dbReference type="OrthoDB" id="424326at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000315">
        <property type="entry name" value="Calcium-dependent protein kinase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000766">
        <property type="entry name" value="CAMK/CDPK protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050205">
        <property type="entry name" value="CDPK_Ser/Thr_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24349">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0106">Calcium</keyword>
    <keyword evidence="14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8 18" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4 18" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="EF-hand" evidence="17">
        <location>
            <begin position="993"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="16">
        <location>
            <begin position="1105"/>
            <end position="1357"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="17">
        <location>
            <begin position="1400"/>
            <end position="1435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="241"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="743"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="243"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="304"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="15">
        <location>
            <begin position="323"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="CRG96276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1557" mass="186189" checksum="A8624C29BF77A906" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVL5</accession>
    <name>A0A1J1GVL5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ethanolamine kinase</fullName>
            <ecNumber evidence="3">2.7.1.82</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">EK</name>
        <name evidence="5" type="ORF">PGAL8A_00351200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from ethanolamine: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the choline/ethanolamine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.82" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529099.1">
        <property type="nucleotide sequence ID" value="XM_028672559.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVL5"/>
    <dbReference type="GeneID" id="39732042"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00351200"/>
    <dbReference type="OMA" id="FALIPKY"/>
    <dbReference type="OrthoDB" id="10267235at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004305">
        <property type="term" value="F:ethanolamine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05157">
        <property type="entry name" value="ETNK_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22603">
        <property type="entry name" value="CHOLINE/ETHANOALAMINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22603:SF66">
        <property type="entry name" value="ETHANOLAMINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01633">
        <property type="entry name" value="Choline_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="15"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00037883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="448" mass="52878" checksum="39AB38C1A7AB3BB6" modified="2017-02-15" version="1">MLKKKEVTFFKLDNIINTQNDMNNMEEKKRKINETEKKNIEEVSINNVTLKNFNNIHNSYSQITEMKNKHGILPLTMSDLKINIGDDKNLKVEEFMTNFISNVFESKNALYLYCKYVLLFYGKDLIDEKNIDSLNFEIIKGGITNILVKVEDNLQKKKYLIRLYGPKTSEIINREREKKISSILCEVNISKKIYVFFPNGRIEEFMDGYALSKEDIKDKEFQKEIAKKLRLLHDISLNDSLFKQLQNLQNIESNESSFLWHTIWKYFNLLNEERKSNYTFSSKKNILNLIDFNMLKLTIKEVEKLCSQKKSPIVLCHCDLLSSNIINGIDGSISFIDFEYSCPMERAFDIANHFNEYAGFNCEWNLIPSRNEEYHFIKHYLKTDDENLIYKLIDEIQPFYLSSHIIWGLWALLQAMHSTIDFDFINYAIHRLSAAYSPIFRCKIDTNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVP9</accession>
    <name>A0A1J1GVP9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">26S proteasome regulatory subunit RPN3, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">RPN3</name>
        <name evidence="5" type="ORF">PGAL8A_00249100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit S3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527904.1">
        <property type="nucleotide sequence ID" value="XM_028671231.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVP9"/>
    <dbReference type="GeneID" id="39731019"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00249100"/>
    <dbReference type="OMA" id="AKVYFYF"/>
    <dbReference type="OrthoDB" id="1713558at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008541">
        <property type="term" value="C:proteasome regulatory particle, lid subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042176">
        <property type="term" value="P:regulation of protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050756">
        <property type="entry name" value="CSN3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013586">
        <property type="entry name" value="PSMD3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057985">
        <property type="entry name" value="TPR_PSMD3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10758:SF2">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10758">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3/COP9 SIGNALOSOME COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08375">
        <property type="entry name" value="Rpn3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25573">
        <property type="entry name" value="TPR_PSMD3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00753">
        <property type="entry name" value="PAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="4">
        <location>
            <begin position="251"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="464"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="466"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="487"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="501" mass="58733" checksum="F4D44A84D8F8E115" modified="2017-02-15" version="1">MKEKYKKVEYAKSDVEIKEIEKDDVNVTFVNNLLTSINYINNAIFYKDNRYILRMLKYIKSMRLSIKSDSHTLMPMIINLINKIFKETHPIYMILNKYINEFKELHKEINEFSNINDKTYSNSLPEIEVFFYIMILLYLLDKKFYEEAMNLSTVIVNRINKLNRRSLDYINAKVYFYYSWVHELGGKLSEVRQKLLYIYRNACLHRDVMTQTVVLNLILRDYIKHNLYDLAVKFISKTSFPENLSSNAQYARYLYYIGKILAIQLDYSEAHSKLIQAIRKAPQNSQSAKGFKLAATKMDIVVELLMGDIPDRSLFSNKYMRKKLIPYKHVVLAVRNGDINKFSKVMGDYNELFIHDGVYLLIKRIHHNVIKTALRIINLSYSRISIKDIGKKIGVESSLDVEGITAKAIHDGVIEATIDYENQYLESKSNSDIYITGEPMKTFHKRIAFCLQLYSDAIKAMQYPDENEKKENEEAKERKIRQQEELAQAEEGDLGDDNDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW22</accession>
    <name>A0A1J1GW22_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00368700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529267.1">
        <property type="nucleotide sequence ID" value="XM_028672745.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW22"/>
    <dbReference type="GeneID" id="39732217"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00368700"/>
    <dbReference type="OMA" id="GYKAWYM"/>
    <dbReference type="OrthoDB" id="359536at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="111" mass="13373" checksum="40EC6AB41E4073B9" modified="2017-02-15" version="1">MGFHIQNYIAMMGRGINPKTWRKLWINYKNKQITHLYNDVAQFTNNQIAQVVRVYQYRYWWWANPFGMGLIFYLGYKAWYMIYMNHKQRKVAQVVASAYGQGGQWLNPVPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWB5</accession>
    <name>A0A1J1GWB5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PIR-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00413200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000065">
        <property type="protein sequence ID" value="CRG96550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529355.1">
        <property type="nucleotide sequence ID" value="XM_028672842.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWB5"/>
    <dbReference type="GeneID" id="39732662"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00413200"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="277"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="373" mass="41312" checksum="BFA1A14F3AF84E65" modified="2017-02-15" version="1">MMIIYIYLLVCIFQYFYSINFEVGKNNLKTELYRRSGRILAEQQQGTSSRRVRSASSIESLFKIWLESFEGEFFDELSKLTKNFTAENAQNFLDSMYKRGGIITKTLNLRPDLDEKSFLNNALTSWRKFSKDVLLDSAIGSYVDSLFNTENITTNNTGLSSALPSTSTSLPIATETFNETILPISTPSPELTISPTALPSASDLSTTADLSPTTSDSHINFTTSSTNDMSDLPTVFSTSGMNNNTTIMNNSTALTPADQGSGLSNAACAGLLCGPTFAALPVSLVLLGGVFFFVLLYMYTPVGKFLGRDNPKKKKAKKRLNEIPMECINSPQLLKVKKKENAKRSVLDRFLRAFGYDKNFPYIDEEIASDQVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWG5</accession>
    <name>A0A1J1GWG5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glycogen synthase kinase 3, putative</fullName>
            <ecNumber evidence="10">2.7.11.26</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">GSK3</name>
        <name evidence="10" type="ORF">PGAL8A_00011600</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.26" evidence="10"/>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528160.1">
        <property type="nucleotide sequence ID" value="XM_028671515.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWG5"/>
    <dbReference type="GeneID" id="39728638"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00011600"/>
    <dbReference type="OMA" id="MKTTMPM"/>
    <dbReference type="OrthoDB" id="272141at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050321">
        <property type="term" value="F:tau-protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030154">
        <property type="term" value="P:cell differentiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14137">
        <property type="entry name" value="STKc_GSK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000082">
        <property type="entry name" value="Shaggy-related protein kinase kappa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050591">
        <property type="entry name" value="GSK-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039192">
        <property type="entry name" value="STKc_GSK3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24057">
        <property type="entry name" value="GLYCOGEN SYNTHASE KINASE-3 ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24057:SF0">
        <property type="entry name" value="PROTEIN KINASE SHAGGY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="68"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG95349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="443" mass="51813" checksum="1B590B96DC47C715" modified="2017-02-15" version="1">MKDWHIDDHINIYQENEKSNNKEYVTYNSCIINKSNENNSSSESSNNSKDQKHRILENEIHRSPNKAYRLGNIVGNGSFGVVYEAICLDTSEKVAIKKVLQDPQYKNRELMIMKNLNHVNIIYLKDYYYTESIKKNEKNIFLNVVMEYIPQTVHKYMKYYSRNNQSIPIFLVKLYSYQLCRALAYLHAKLICHRDLKPQNLLIDPKTHTLKLCDFGSAKNLLVGQRSVSYICSRFYRAPELMLGSTNYTTHIDLWSLGCIIAEMILGFPLFSGQSSVDQLVRIIQVLGTPTEEQMKEMNPNYADVKFPDVKPKDLKKIFPKSTSEDAINLVSRFLKYEPLKRLSSIEALSDPFFDELRDPSIKLPKYIDKLPELFNFCEEEIKVMSDECRKKVLPKHLYEKYEYLMNEHNNNNSVNENINKEFNESNMENNQSNNKSHLIIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWH8</accession>
    <name>A0A1J1GWH8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00285800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528469.1">
        <property type="nucleotide sequence ID" value="XM_028671858.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWH8"/>
    <dbReference type="GeneID" id="39731391"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00285800"/>
    <dbReference type="OrthoDB" id="378454at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="179"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="265" mass="31167" checksum="1EC3E1BF1766C940" modified="2017-02-15" version="1">MSAGAVGVENRYLMKNKKNKNNSHECINVDINHIIKDIYGYKNGRKRNIQFIYDDTIINQDTKKINKKVKTENNNFSNIIKCDNENENKKDDSVTYEDINNNNYCNYTEFNDLKNNDIVNVSPSLLSPKEENLKFISRKIESCIDNILESILTCNEINQAKRIMIPLLSDFIQNNFINNDDYEKNQNSYKLKIDTLQKEKKVLISAVKIQYQKIAQFQKLIENQKNELKKKSDELNQIKAKVHQYFYDINNPNKRNFSILSPDVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWI9</accession>
    <name>A0A1J1GWI9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00014200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528184.1">
        <property type="nucleotide sequence ID" value="XM_028671542.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWI9"/>
    <dbReference type="GeneID" id="39728664"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00014200"/>
    <dbReference type="OMA" id="NVHINIY"/>
    <dbReference type="OrthoDB" id="10380718at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016194">
        <property type="entry name" value="SPOC-like_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100939">
        <property type="entry name" value="SPOC domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="684" mass="81673" checksum="805399902C186032" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWN4</accession>
    <name>A0A1J1GWN4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">PRP2</name>
        <name evidence="11" type="ORF">PGAL8A_00453300</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529756.1">
        <property type="nucleotide sequence ID" value="XM_028673288.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWN4"/>
    <dbReference type="GeneID" id="39733066"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00453300"/>
    <dbReference type="OMA" id="ECKYHLY"/>
    <dbReference type="OrthoDB" id="10253254at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17917">
        <property type="entry name" value="DEXHc_RHA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002057">
        <property type="entry name" value="Pre-mRNA splicing factor RNA helicase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF83">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="349"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="537"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG96953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1017" mass="118556" checksum="171F2898F69276F0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWV4</accession>
    <name>A0A1J1GWV4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Mitochondrial carrier protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00462300</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529846.1">
        <property type="nucleotide sequence ID" value="XM_028673389.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWV4"/>
    <dbReference type="GeneID" id="39733156"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00462300"/>
    <dbReference type="OMA" id="IGPRTMW"/>
    <dbReference type="OrthoDB" id="276989at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45667">
        <property type="entry name" value="S-ADENOSYLMETHIONINE MITOCHONDRIAL CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="136"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="82"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="177"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG97043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="262" mass="29943" checksum="31E84A9AEC41DF9D" modified="2017-02-15" version="1">MEHLKNLIIGALSGVVVDSVLFPIDNLKTRAQAQKCFSIFETYKLYNGILPTLLGTVPASAFFYCFYEMSKKLLTEYNPNISKSHLYLISTSVAEIASCSVRLPFEIVKQRMQISDNSSLINTIYDISKKEGLYKYLLKSYLIMIVREIPFDFIQFFLWETFKEVAKKNFGKYSDKHPTITSSICGGLAGGISGFLTTPMDVIKSRQMIYGKHFNEIILEISNEGYLSFYKGCYYRTCYLFFGGLIFFGSLKFFSLLLKNDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX01</accession>
    <name>A0A1J1GX01_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TetQ family GTPase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00457100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529794.1">
        <property type="nucleotide sequence ID" value="XM_028673331.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX01"/>
    <dbReference type="GeneID" id="39733104"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00457100"/>
    <dbReference type="OMA" id="TCAIEPK"/>
    <dbReference type="OrthoDB" id="364892at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032790">
        <property type="term" value="P:ribosome disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01514">
        <property type="entry name" value="Elongation_Factor_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43261:SF1">
        <property type="entry name" value="RIBOSOME-RELEASING FACTOR 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43261">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="4">
        <location>
            <begin position="22"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1068" mass="125206" checksum="3A731272E1C1D59C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GX35</accession>
    <name>A0A1J1GX35_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">S-adenosyl-methyltransferase, putative</fullName>
            <ecNumber evidence="5">2.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00458400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. RsmH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529807.1">
        <property type="nucleotide sequence ID" value="XM_028673346.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GX35"/>
    <dbReference type="GeneID" id="39733117"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00458400"/>
    <dbReference type="OMA" id="YTEKEYI"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071424">
        <property type="term" value="F:rRNA (cytosine-N4-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.170">
        <property type="entry name" value="Putative methyltransferase TM0872, insert domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01007">
        <property type="entry name" value="16SrRNA_methyltr_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002903">
        <property type="entry name" value="RsmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023397">
        <property type="entry name" value="SAM-dep_MeTrfase_MraW_recog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11265:SF0">
        <property type="entry name" value="12S RRNA N4-METHYLCYTIDINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11265">
        <property type="entry name" value="S-ADENOSYL-METHYLTRANSFERASE MRAW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01795">
        <property type="entry name" value="Methyltransf_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81799">
        <property type="entry name" value="Putative methyltransferase TM0872, insert domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="475" mass="56063" checksum="A0D653C3EA6C5E43" modified="2017-02-15" version="1">MYKLLAILICLINNYKCYKIKNWKNYCEPFHLNYLVKKSKVSYKSNKFTNSFFSLRNNVREENESNIYDKSYVYHTPVLLSEVIQYINNKEECNKLNECINNSDKIELKLNSSPSNKNITNLNINKRCIDKEKCFLYESKDLKGMEKKNLRNYDSIKSFHISKEQKNTNGGEENNYYIDATLGGGGHTLEILKKIENSKVIAIDKDIESIYYNKLKLKNYIDKNRLFLIHGDYRNILHLLNYNSLPLSNYSGILIDLGVSSHQLKSIRRGFSYKYNGILDMNMNKYTEEEFVNSYFSNKNYSTISNNSDNINNKIHNILNTYSLKKLKFIIETFGEEKKALKIAKKIVQWRKNNGKIVTTYDLKHIVLLTCKKNYKSNNKVLSRVFQSFRIYINDELKALKEFLISAHKILKPTKRLITISYHSLEHMCIEKFVERKKKLWIKINKNAITPSENEIKLNNSSRSAKMFVFEKRKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXK0</accession>
    <name>A0A1J1GXK0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00460200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529825.1">
        <property type="nucleotide sequence ID" value="XM_028673365.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733135"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00460200"/>
    <dbReference type="OMA" id="ENETHKS"/>
    <dbReference type="OrthoDB" id="372279at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="714"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="851"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="930"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="288"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="714"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="853"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="933"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="953"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="976"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1011"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1040"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1068"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1095"/>
            <end position="1122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1661" mass="196649" checksum="D172EFDED247CA25" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXW5</accession>
    <name>A0A1J1GXW5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Midasin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">PGAL8A_00306000</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the midasin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528656.1">
        <property type="nucleotide sequence ID" value="XM_028672066.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39731593"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00306000"/>
    <dbReference type="OMA" id="SECTDIY"/>
    <dbReference type="OrthoDB" id="5186at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000142">
        <property type="entry name" value="Midasin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040848">
        <property type="entry name" value="AAA_lid_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011704">
        <property type="entry name" value="ATPase_dyneun-rel_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041190">
        <property type="entry name" value="Midasin_AAA_lid_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48103:SF2">
        <property type="entry name" value="MIDASIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48103">
        <property type="entry name" value="MIDASIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07728">
        <property type="entry name" value="AAA_5"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17865">
        <property type="entry name" value="AAA_lid_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17867">
        <property type="entry name" value="AAA_lid_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="319"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="3119"/>
            <end position="3138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="3150"/>
            <end position="3166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="3172"/>
            <end position="3190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="3280"/>
            <end position="3302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="3440"/>
            <end position="3460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="3472"/>
            <end position="3491"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="3726"/>
            <end position="3749"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="3850"/>
            <end position="3872"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="4062"/>
            <end position="4079"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="5555"/>
            <end position="5571"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="5762"/>
            <end position="5788"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="12">
        <location>
            <begin position="6821"/>
            <end position="7025"/>
        </location>
    </feature>
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        <location>
            <begin position="2292"/>
            <end position="2313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="5888"/>
            <end position="6086"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="6125"/>
            <end position="6336"/>
        </location>
    </feature>
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        <location>
            <begin position="6553"/>
            <end position="6591"/>
        </location>
    </feature>
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        <location>
            <begin position="6625"/>
            <end position="6650"/>
        </location>
    </feature>
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        <location>
            <begin position="1907"/>
            <end position="1934"/>
        </location>
    </feature>
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        <location>
            <begin position="4908"/>
            <end position="4935"/>
        </location>
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            <end position="6437"/>
        </location>
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            <begin position="6495"/>
            <end position="6525"/>
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        <location>
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            <end position="2313"/>
        </location>
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            <begin position="5904"/>
            <end position="5917"/>
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        <location>
            <begin position="5918"/>
            <end position="5932"/>
        </location>
    </feature>
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            <begin position="5933"/>
            <end position="5948"/>
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            <begin position="5970"/>
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        <location>
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        <location>
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        <location>
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            <end position="6170"/>
        </location>
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        <location>
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            <end position="6191"/>
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            <end position="6203"/>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="6204"/>
            <end position="6242"/>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="6250"/>
            <end position="6305"/>
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        <location>
            <begin position="6306"/>
            <end position="6318"/>
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        <location>
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        <location>
            <begin position="6559"/>
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            <end position="6650"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004642"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00007188"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00017143"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CRG95848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="7036" mass="840611" checksum="2283631FCEB68870" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXY8</accession>
    <name>A0A1J1GXY8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-e protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00474500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
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            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
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    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000090">
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    </dbReference>
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    <dbReference type="GeneID" id="39733278"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00474500"/>
    <dbReference type="Proteomes" id="UP000220797">
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="268" mass="32235" checksum="5BE4BC150CCC2F44" modified="2017-02-15" version="1" fragment="single">KICILKKKKKKKPYRSSRIIILSDNNQDGIVFLYEYNVHYDPYPTKTYLCRLRNINQTAALCESVDIYYLDKRLYFSSYDFISEKNDQPLKHLKNPNHKIIKSKYKDLFIKEHSCHHIKTRYISRRSCMYAICEKKNEDYMLCSDANYSGKLIFLDDYNLINRKFIYLPEGCLKIDSNFACNAYFCEINAKDKFFPCDHKEISAIKDVMPYARRSEVMPIEQQIVHHEDNLSASALSAMTLMPFLIIFVFFWCYIYKYFKKRRRRKIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYB9</accession>
    <name>A0A1J1GYB9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cytoadherence linked asexual protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00321300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
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    <reference evidence="3" key="1">
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            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000048">
        <property type="protein sequence ID" value="CRG96000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="CLAG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03805">
        <property type="entry name" value="CLAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013198725" evidence="2">
        <location>
            <begin position="25"/>
            <end position="1421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1223"/>
            <end position="1241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1421" mass="170052" checksum="871816F6DB41CD56" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYD5</accession>
    <name>A0A1J1GYD5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00322900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000049">
        <property type="protein sequence ID" value="CRG96016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528824.1">
        <property type="nucleotide sequence ID" value="XM_028672253.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYD5"/>
    <dbReference type="GeneID" id="39731762"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00322900"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006496">
        <property type="entry name" value="CHP01606_Plasmodium_spp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09688">
        <property type="entry name" value="Wx5_PLAF3D7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
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            <end position="355"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="170"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
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            <begin position="198"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="220"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG96016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="374" mass="45052" checksum="1F45CD172BB5E786" modified="2017-02-15" version="1">MKTLILFLKITTFLLLIWMYLFFYNCDSYKNLIDKNILQTKNELKYERVLTEGDTAGQKQTNCEGCKEECPVEKKKKEKKKKYRYIPLVRQNPYDRWQTVNNPTLFERFKNETIGMDDKWRDQKWNNEWNKISANKVNELSSIFNQSDISKKEKEKLIYTVKDELFGLFANFLKECKKEIRDNKAEYESKKEMIGNKTESEYMKEMGENGRQSESMNEMIDNKAKSESENEMRDNKMESESEKEMRDNKAECESEKEMRDNRTESESIKEMIDNRTESESIKEMIDNRTETESMKEMIENKAESESEKEMRYDKTESESRKEMRDNKEESESEEEMRYDKTESESRKEQGTNEIKNYKKKIRELLIVLIILRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYF2</accession>
    <name>A0A1J1GYF2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00516100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530389.1">
        <property type="nucleotide sequence ID" value="XM_028673992.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYF2"/>
    <dbReference type="GeneID" id="39733694"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00516100"/>
    <dbReference type="OMA" id="NGNIAYN"/>
    <dbReference type="OrthoDB" id="376712at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012294778" evidence="2">
        <location>
            <begin position="26"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="143" mass="16835" checksum="918B6D966EC3902A" modified="2017-02-15" version="1">MRKLFLFLFFTFTYFFLFKVRKCKANYKNGNIAYNPNYNTDLSSINSINEKVETQKGKKKNLTKTILKGIGIFFMLATSINLILQNAVLNEELSNHKRREIDLTARLMNAERDVLTSKIEYSRKVEEMQNVINHMIVHTFNNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYQ5</accession>
    <name>A0A1J1GYQ5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00335400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528944.1">
        <property type="nucleotide sequence ID" value="XM_028672386.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYQ5"/>
    <dbReference type="GeneID" id="39731884"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00335400"/>
    <dbReference type="OMA" id="FFIPPME"/>
    <dbReference type="OrthoDB" id="392930at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="828"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="674"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="833"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="844"/>
            <end position="853"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="853" mass="101046" checksum="D782D1F2B293D80C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYS3</accession>
    <name>A0A1J1GYS3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Histone H2B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">PGAL8A_00518600</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the histone H2B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530414.1">
        <property type="nucleotide sequence ID" value="XM_028674019.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYS3"/>
    <dbReference type="GeneID" id="39733719"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00518600"/>
    <dbReference type="OMA" id="FCPFAIR"/>
    <dbReference type="OrthoDB" id="1166527at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22910">
        <property type="entry name" value="HFD_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000043">
        <property type="entry name" value="Histone H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000558">
        <property type="entry name" value="Histone_H2B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055333">
        <property type="entry name" value="HISTONE_H2B_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23428">
        <property type="entry name" value="HISTONE H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00621">
        <property type="entry name" value="HISTONEH2B"/>
    </dbReference>
    <dbReference type="SMART" id="SM00427">
        <property type="entry name" value="H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00357">
        <property type="entry name" value="HISTONE_H2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 8" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="10">
        <location>
            <begin position="24"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG97613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="123" mass="13735" checksum="EBCFB32EA863220C" modified="2017-02-15" version="1">MSGKGPAQKSQAAKKTAGKTLGPRHKRKRRTESFSLYIFKVLKQVHPETGVTKKSMNIMNSFINDIFDRLVTEATRLIRYNKKRTLSSREIQTAVRLLLPGELSKHAVSEGTKAVTKYTTSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYW7</accession>
    <name>A0A1J1GYW7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fam-b protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00534800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530571.1">
        <property type="nucleotide sequence ID" value="XM_028674193.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYW7"/>
    <dbReference type="GeneID" id="39733881"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00534800"/>
    <dbReference type="OrthoDB" id="375294at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013244174" description="Fam-b protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="251"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="288"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="341" mass="40969" checksum="A06EA5AC3EE24D5D" modified="2017-02-15" version="1">MIIKFILFILFIKTYNSFQFNYKILPKSDYKHNCVKKFPSVNYFYKFQNVKSKEFKNKILSFFSNYFNRESDKYTLNQDEKDYLNKLGVSENDDYKDLVKSHEEYIKTISDIKSKLKYKDLFFFITQKLIHKNLYEFKRKQKYNIFQNDEYTSELSIDYVKNSNIEEKFKEILLKKLSRENNSHKFRLLRIFKWKSASDIFNISKLIIPIASIGLFLSKMAIFSVVVNMIITAHFLTFKKDQKKKMKISTLILTMVLILVHSSFGIVCNSIFFHYFKFNIPTYIKRENILSIFVNIQLYIASLIYFTNNNNHENEDVNEDVNDSIFNNIDFDDEFSLEKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYX9</accession>
    <name>A0A1J1GYX9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00524500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530470.1">
        <property type="nucleotide sequence ID" value="XM_028674081.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYX9"/>
    <dbReference type="GeneID" id="39733778"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00524500"/>
    <dbReference type="OrthoDB" id="391704at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009618947" evidence="1">
        <location>
            <begin position="21"/>
            <end position="1204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1204" mass="144126" checksum="1C24B388C5566D10" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ60</accession>
    <name>A0A1J1GZ60_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Perforin like protein 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00531300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530537.1">
        <property type="nucleotide sequence ID" value="XM_028674156.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ60"/>
    <dbReference type="GeneID" id="39733846"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00531300"/>
    <dbReference type="OMA" id="THVAHEM"/>
    <dbReference type="OrthoDB" id="1366754at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020864">
        <property type="entry name" value="MACPF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19324:SF33">
        <property type="entry name" value="MUCIN-5AC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19324">
        <property type="entry name" value="PERFORIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01823">
        <property type="entry name" value="MACPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51412">
        <property type="entry name" value="MACPF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MACPF" evidence="2">
        <location>
            <begin position="428"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="406"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1057" mass="121905" checksum="53AF38741EC02020" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZC3</accession>
    <name>A0A1J1GZC3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Ran-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00422900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the exportin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529453.1">
        <property type="nucleotide sequence ID" value="XM_028672951.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZC3"/>
    <dbReference type="GeneID" id="39732761"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00422900"/>
    <dbReference type="OMA" id="DCFHELC"/>
    <dbReference type="OrthoDB" id="244158at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005049">
        <property type="term" value="F:nuclear export signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006611">
        <property type="term" value="P:protein export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000332">
        <property type="entry name" value="Ran-binding protein 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057947">
        <property type="entry name" value="TPR_XPO7/RBP17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044189">
        <property type="entry name" value="XPO4/7-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12596">
        <property type="entry name" value="EXPORTIN 4,7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12596:SF2">
        <property type="entry name" value="EXPORTIN-7 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25795">
        <property type="entry name" value="TPR_XPO7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exportin-7/Ran-binding protein 17 TPR repeats" evidence="8">
        <location>
            <begin position="476"/>
            <end position="733"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF25795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG96649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1187" mass="138167" checksum="FB6BB3BEB16E6A30" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZC6</accession>
    <name>A0A1J1GZC6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RNA-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00359500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529176.1">
        <property type="nucleotide sequence ID" value="XM_028672645.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZC6"/>
    <dbReference type="GeneID" id="39732125"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00359500"/>
    <dbReference type="OrthoDB" id="266020at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="884"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="999"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="309"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="325"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="342"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG96371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1102" mass="128508" checksum="07C4EC9382F2796E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZF1</accession>
    <name>A0A1J1GZF1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00028100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530646.1">
        <property type="nucleotide sequence ID" value="XM_028674277.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZF1"/>
    <dbReference type="GeneID" id="39728804"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00028100"/>
    <dbReference type="OMA" id="FHPADGK"/>
    <dbReference type="OrthoDB" id="436298at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="105" mass="12591" checksum="F008041DA9E4A6C5" modified="2017-02-15" version="1">MSINRINKIILCSKVELKSIEKIDFYTNTSKSIVKDFCEFFLPFLKYNNFNVVCNFHNIKEKNEKVVLSPKNRDIHIINLCLYKYSQQLYDRIIFLDKKFSEAQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZF5</accession>
    <name>A0A1J1GZF5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BCNT-C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00026800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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</entry>
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            <strain evidence="9">8A</strain>
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</entry>
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            <strain evidence="9">8A</strain>
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    </reference>
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        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H093</accession>
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        <submittedName>
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        </source>
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    <comment type="subcellular location">
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        <subcellularLocation>
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        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR38796:SF1">
        <property type="entry name" value="ANCHORED PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G09600)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07422">
        <property type="entry name" value="s48_45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00970">
        <property type="entry name" value="s48_45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51701">
        <property type="entry name" value="6_CYS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="471"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="11">
        <location>
            <begin position="17"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="6-Cys" evidence="11">
        <location>
            <begin position="167"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="310"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG98116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="495" mass="57657" checksum="4A6D07F2F7697793" modified="2017-02-15" version="1">MLDNLEQNMKHKKVLLYYFLCVIYNYVVHSNRIKPVQKIGNVNLCIVNTRSDEVEECILENEFGKLLLFICKVDDSNSLIARAKPAECASKTYVNQNNPNENSPETNTYDIFQNLYGTNNSSLTASFAFYGTPYSNKDIEFSCLCYGDKKTNIKNIMRINFRKTSKKIKGCDFGDNVKSRRDLTSNRTLNENSSCVVHAFPGDIIGINCFKKYNDNSYNDKLELIPNKCFHNIFYGYDLVLNSKNLIPNSRVIPDPSSDVELTKMHSFFSYLILPDNLQENLRIGCACKRNQYAGYMVIYTKTRNNFLDDDNNEGKYSVKGSSEQHNQDESIEPIEPVNPVERIEQVEPVEPVEPVEPVKPVEPVKPVKPVEPVKQNERVERIVKKVDPIEQIEHIDNDIQNDQNYSNYHNEQNLDTQKYIYGYDNSNNSDNENTEDTERIFYKNGDEEYDIRDRLNMDKRKSRRTFWQNLFGLSSSYYLGLNYLLYMFLFIQIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0A4</accession>
    <name>A0A1J1H0A4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Asparagine-rich protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00061400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530974.1">
        <property type="nucleotide sequence ID" value="XM_028674641.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0A4"/>
    <dbReference type="GeneID" id="39729139"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00061400"/>
    <dbReference type="OMA" id="RKIYQNM"/>
    <dbReference type="OrthoDB" id="378554at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1078"/>
            <end position="1108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1126" mass="130411" checksum="272013C0E098F008" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0F0</accession>
    <name>A0A1J1H0F0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SHSP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00458200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529805.1">
        <property type="nucleotide sequence ID" value="XM_028673343.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0F0"/>
    <dbReference type="GeneID" id="39733115"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00458200"/>
    <dbReference type="OMA" id="NTEKVFY"/>
    <dbReference type="OrthoDB" id="374555at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06464">
        <property type="entry name" value="ACD_sHsps-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SHSP" evidence="1">
        <location>
            <begin position="182"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="256" mass="30734" checksum="EF7541075390571C" modified="2017-02-15" version="1">MDRIEVLKKNLNVEKVFSHLNWHELILDELSDDSHYEKLESYKNCNDLFSYPSQHNEDDYVSKKKALKKKKKLGNISNEKNYNCYSRDKCTNKNEEIEEKNEIAKSNTNNDYKCYFFQNISLFSYISNLFSREKKKYEMKKCNFIKEVKKGLTNKIDFIPPVNILYDDEKVIFLFFISGVLENFNIFTLNNYITISGKKVPYEVQRCTNYFSHEITTGYFMRTYYFTKSFDKEKIHYEHKNGVTQIYVYISNDHVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0J2</accession>
    <name>A0A1J1H0J2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ubiquitin regulatory protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00051800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530880.1">
        <property type="nucleotide sequence ID" value="XM_028674538.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0J2"/>
    <dbReference type="GeneID" id="39729043"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00051800"/>
    <dbReference type="OMA" id="SRCQRSC"/>
    <dbReference type="OrthoDB" id="25887at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061025">
        <property type="term" value="P:membrane fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031468">
        <property type="term" value="P:nuclear membrane reassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01770">
        <property type="entry name" value="UBX_UBXN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000270">
        <property type="entry name" value="Ubiquitin regulatory protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.210">
        <property type="entry name" value="SEP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036241">
        <property type="entry name" value="NSFL1C_SEP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012989">
        <property type="entry name" value="SEP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23333:SF20">
        <property type="entry name" value="NSFL1 COFACTOR P47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23333">
        <property type="entry name" value="UBX DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08059">
        <property type="entry name" value="SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00553">
        <property type="entry name" value="SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102848">
        <property type="entry name" value="NSFL1 (p97 ATPase) cofactor p47, SEP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51399">
        <property type="entry name" value="SEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SEP" evidence="2">
        <location>
            <begin position="57"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="UBX" evidence="1">
        <location>
            <begin position="167"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="242" mass="28142" checksum="3077D3E12F2EEB31" modified="2017-02-15" version="1">MHNFFYELFRSLSDLRKDEKKKKERISHYTGGHNSGLEVENSDDDLVQNFLSSKLSENCRHITLYKNGFIIDDGEFRDLEVEENKKFMENIEAGILPKELASKDKTVNVALKDKSNQIYTKKKQKDDDLYKGQGIKLGGNTSNTNEEELNKLLTSSPSEVKKINIDENKPLTTLHVRLYNGRKISQKFNYDHTVEDLFQYVYSVTPINFSLYFDFPLKLIERNEQTLENANLLDTIITQKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0M6</accession>
    <name>A0A1J1H0M6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Kinesin, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00466300</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529885.1">
        <property type="nucleotide sequence ID" value="XM_028673432.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733196"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00466300"/>
    <dbReference type="OMA" id="CKSILIC"/>
    <dbReference type="OrthoDB" id="3176171at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968">
        <property type="entry name" value="CENTROMERE PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968:SF36">
        <property type="entry name" value="KINESIN HEAVY CHAIN ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0493">Microtubule</keyword>
    <keyword evidence="5 6" id="KW-0505">Motor protein</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="9">
        <location>
            <begin position="78"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="517"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="655"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1152"/>
            <end position="1179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="517"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="656"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="166"/>
            <end position="173"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG97082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1345" mass="156619" checksum="64DB08AF4B3C2DD0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2F0</accession>
    <name>A0A1J1H2F0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GYF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00508300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530311.1">
        <property type="nucleotide sequence ID" value="XM_028673905.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2F0"/>
    <dbReference type="GeneID" id="39733616"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00508300"/>
    <dbReference type="OMA" id="CMMSYEM"/>
    <dbReference type="OrthoDB" id="392750at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003169">
        <property type="entry name" value="GYF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035445">
        <property type="entry name" value="GYF-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02213">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00444">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55277">
        <property type="entry name" value="GYF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50829">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GYF" evidence="3">
        <location>
            <begin position="210"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="343"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="504"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="434"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="509"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="529"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1163" mass="139920" checksum="0EC8EE60926DBBE7" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2K1</accession>
    <name>A0A1J1H2K1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Structural maintenance of chromosomes protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PGAL8A_00514700</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SMC family. SMC2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530375.1">
        <property type="nucleotide sequence ID" value="XM_028673975.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2K1"/>
    <dbReference type="GeneID" id="39733680"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00514700"/>
    <dbReference type="OMA" id="ECAGTTI"/>
    <dbReference type="OrthoDB" id="10255539at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030261">
        <property type="term" value="P:chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03273">
        <property type="entry name" value="ABC_SMC2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1060.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024704">
        <property type="entry name" value="SMC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027120">
        <property type="entry name" value="Smc2_ABC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010935">
        <property type="entry name" value="SMC_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
        <property type="entry name" value="SMC_hinge_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43977">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06470">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005719">
        <property type="entry name" value="SMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00968">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75553">
        <property type="entry name" value="Smc hinge domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="7 12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC hinge" evidence="14">
        <location>
            <begin position="524"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1195"/>
            <end position="1218"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="247"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="688"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="979"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1196"/>
            <end position="1218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR005719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG97574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1218" mass="143353" checksum="280A865D40D4D8D8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2S5</accession>
    <name>A0A1J1H2S5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GDP-mannose 4,6-dehydratase</fullName>
            <ecNumber evidence="3">4.2.1.47</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00522200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.47" evidence="3"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530447.1">
        <property type="nucleotide sequence ID" value="XM_028674056.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2S5"/>
    <dbReference type="GeneID" id="39733755"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00522200"/>
    <dbReference type="OMA" id="AFRDWSH"/>
    <dbReference type="OrthoDB" id="10253554at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008446">
        <property type="term" value="F:GDP-mannose 4,6-dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042351">
        <property type="term" value="P:'de novo' GDP-L-fucose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05260">
        <property type="entry name" value="GDP_MD_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000924">
        <property type="entry name" value="GDP-mannose 4,6 dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00955">
        <property type="entry name" value="GDP_Man_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006368">
        <property type="entry name" value="GDP_Man_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01472">
        <property type="entry name" value="gmd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43715:SF1">
        <property type="entry name" value="GDP-MANNOSE 4,6 DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43715">
        <property type="entry name" value="GDP-MANNOSE 4,6-DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="5">
        <location>
            <begin position="5"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG97646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="362" mass="41990" checksum="F9B09A816D425C12" modified="2017-02-15" version="1">MNVALIFGITGQDGSYLSELLLEKGYEVHGVIRRCSSFNTKRIDHIFDKLILHYGDVIDSSNICSLISKVKPTEIYNLAAQSHVKVSFEVPEYTAETTAVGTLRILEAIKISKIKNLKFYNASTSELFGKVKCIPQKEDTPFYPVSPYAIAKLYAHYITINYRESYNMFCVNGILFNHESPRRGETFVTRKITRGIAKIYKKLQNFITLGNIDTYRDWGHAKDYVYAMYLMLQEKEPQDFVICSNEQHSVREFCEISFSFVGIYIKWIGEGINEVGVSQNNEIVINKSSKYFRKCEVNTLLGDCSKAKKILKWEPTYNFTQLIYEMLKYDFDDYNIPIDDYETCLKRYENYKNTKISEIVNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3P7</accession>
    <name>A0A1J1H3P7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00040300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000123">
        <property type="protein sequence ID" value="CRG97968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530767.1">
        <property type="nucleotide sequence ID" value="XM_028674411.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3P7"/>
    <dbReference type="GeneID" id="39728927"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00040300"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="286" mass="34164" checksum="32FC54E10AE27F9F" modified="2017-02-15" version="1">MESVNKCVIGTKIFIKDKNKCDSYKTLVDKNILQTKNELKYGRVLAEGEITGKKQSNAEGCLKECPLDNKKNICKDPDLYKDPFNYYRKVMIPQFSKRFNKETNEMDPKSKSLKWNAYWNEISTTKVRDLYSISRRRNIRDEEKNKKIDIIMRELDSEFEKFLCECKKEMTDNKTESESNKVMRDNITESESEEEMRENKTESESEEEMRENKTESESEEEMRENKTEFESKKEMRDNKTVSESEKEMRYNKIESESKKEQGTNEIRNYKKKIWQLLIVLIILGRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H4D2</accession>
    <name>A0A1J1H4D2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00064100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530999.1">
        <property type="nucleotide sequence ID" value="XM_028674670.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H4D2"/>
    <dbReference type="GeneID" id="39729166"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00064100"/>
    <dbReference type="OrthoDB" id="371455at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG98202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="299" mass="35935" checksum="713507E2DF6BEF64" modified="2017-02-15" version="1">MLGENLIIERTMKDGMNIFVYNNYAIWVTKFSHLYFFFFFSIRNIFHFSTNLIFLIFFFGFVFIFFFFCMCWYSFYKFIKKILDANLLEDEEINPSILNEIIPQIFFSICNFLSIKLLYIGHLLVYLNLQDDVIFVPVESLIIFFIYFIACICYACLFKYENSMSVFLVGLNGIITLLFFIFKEKYIFLPSLLCSGYYLIYRINSFNRNKFLYHEAEENYMKILLRGCALNFIALFLKNFYLINIQIFSFLLLIAFVMFVYSDLNLQKMEILYEPMENRILYNYISSFQLNNKTPGTLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2012-07-11" modified="2026-01-28" version="44" xmlns="https://uniprot.org/uniprot">
    <accession>I2FKD6</accession>
    <name>I2FKD6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="18 19">Cytochrome c1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="primary">CYT1</name>
        <name evidence="19" type="ORF">PGAL8A_00222100</name>
    </gene>
    <organism evidence="18">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2012" name="Gene" volume="502" first="36" last="39">
            <title>Age of the last common ancestor of extant Plasmodium parasite lineages.</title>
            <authorList>
                <person name="Hayakawa T."/>
                <person name="Tachibana S."/>
                <person name="Hikosaka K."/>
                <person name="Arisue N."/>
                <person name="Matsui A."/>
                <person name="Horii T."/>
                <person name="Tanabe K."/>
            </authorList>
            <dbReference type="PubMed" id="22555021"/>
            <dbReference type="DOI" id="10.1016/j.gene.2012.04.037"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
    </reference>
    <reference evidence="19 20" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </cofactor>
        <text evidence="14">Binds 1 heme c group covalently per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome c family.</text>
    </comment>
    <dbReference type="EMBL" id="AB571145">
        <property type="protein sequence ID" value="BAM15621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="I2FKD6"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00222100"/>
    <dbReference type="OMA" id="KNRHTDY"/>
    <dbReference type="OrthoDB" id="5925at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.760.10:FF:000011">
        <property type="entry name" value="Cytochrome c1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="entry name" value="Cytochrome c-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.100">
        <property type="entry name" value="Cytochrome c1, transmembrane anchor, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002326">
        <property type="entry name" value="Cyt_c1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021157">
        <property type="entry name" value="Cyt_c1_TM_anchor_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10266">
        <property type="entry name" value="CYTOCHROME C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10266:SF3">
        <property type="entry name" value="CYTOCHROME C1, HEME PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02167">
        <property type="entry name" value="Cytochrom_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00603">
        <property type="entry name" value="CYTOCHROMEC1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="Cytochrome c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81496">
        <property type="entry name" value="Cytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4 14 15" id="KW-0349">Heme</keyword>
    <keyword evidence="11 14 15" id="KW-0408">Iron</keyword>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 14 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="6 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="356"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="17">
        <location>
            <begin position="175"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="14">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="14">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="14">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="14">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR602326-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="BAM15621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="CRG94824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="394" mass="45865" checksum="3A4E79EE6BDAB6A2" modified="2012-07-11" version="1">MAGGGALNNLFPGYKDKIWLKLPYQFRVYLIKSWNKEFERNISKAKIKNNRIKNLNFYILDKLKPNDSYKNSHTDYKRQICRGTLEEGCDFYLPDKKSQDRLKNHLEPYTDEENENRKNFKYLNLKYYLLCAFGFTIIHNSFQSRPVAWCMDSEPPHPPHYPFWFKSLFHSHDIPSVRRGFEVYRQICATCHSMEQLQFRHLVNEVYPENRVKQIAASYDIVDGPDDKGEMFTRPGILTDSFPKPYPNDEAARYANGGAVPPDLSVITSARHNGPDYLFALLTGYRDPPQGVVLRPGLYYNTYFPGGSISMPPPLQDDMIEYEDGTPCNVSQMAKDVVNFLCWATEPTHDERKLTALKLICGAFVAMVLMTVWQRFFWTVYATRRIDFGKVKYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL45</accession>
    <name>A0A1J1GL45_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00083000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000013">
        <property type="protein sequence ID" value="CRG93126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525948.1">
        <property type="nucleotide sequence ID" value="XM_028670777.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL45"/>
    <dbReference type="GeneID" id="39729354"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00083000"/>
    <dbReference type="OMA" id="YELWKLC"/>
    <dbReference type="OrthoDB" id="361829at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012949802" evidence="2">
        <location>
            <begin position="18"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="405"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="410"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="431"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="450" mass="54646" checksum="9D57183AB26C2151" modified="2017-02-15" version="1">MKILIFIILTIFTITLENNLSNSFYIQNNYSNKKDYSNRIYVSRPAQKKSNQLKTKIIINKRKKEENEKNKSYKEDFKSSPKYKSIEELINEYPYKIPDYDIQKEPYIILKDKIKSEYLKGYELPFGLIDPVKYELLKLIGKICDPFKPLCCYSLTPRLLISKLFTNKYEISYDDFCYNLEYKMRFYMPSYTQIFMYEKELLWKEWMAIRNLKEVSPETPIDDHDRVTRILEDDEATLPNTILKVNREINNQGIHPSILRMFFDFLNIEKCDNKLKRDNAFLKLETIKSQIKNRDFMEGIRPDYLYIMFNKTAHDYYSNFNEKEYEKTYLESVNYNTMRQKIISENSLYKKQRKEFSEKTKNSLMKFYDIELPSFFKEYIEKKKENYKIIQSKIKTMIDNKYLKRKKKREDKLSGKITLDTKTEENTEEKKKKKKKKKKKKKKKKKVTMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GL99</accession>
    <name>A0A1J1GL99_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Coatomer subunit zeta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">PGAL8A_00088800</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 12">Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 12">Golgi apparatus membrane</location>
            <topology evidence="1 12">Peripheral membrane protein</topology>
            <orientation evidence="1 12">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Cytoplasmic vesicle</location>
            <location evidence="12">COPI-coated vesicle membrane</location>
            <topology evidence="12">Peripheral membrane protein</topology>
            <orientation evidence="12">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the adaptor complexes small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526006.1">
        <property type="nucleotide sequence ID" value="XM_028671422.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GL99"/>
    <dbReference type="GeneID" id="39729412"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00088800"/>
    <dbReference type="OMA" id="NYYSDDW"/>
    <dbReference type="OrthoDB" id="6585768at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039652">
        <property type="entry name" value="Coatomer_zeta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11043:SF0">
        <property type="entry name" value="COATOMER SUBUNIT ZETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11043">
        <property type="entry name" value="ZETA-COAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 12" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6 12" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AP complex mu/sigma subunit" evidence="13">
        <location>
            <begin position="9"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU366053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG93184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="208" mass="23758" checksum="4FF6A0B548F2F8D3" modified="2017-02-15" version="1">MKSISIKQLEAIVILDTDGKRIAVKYYNDKLSFKGEDKLNNLISSKESINYNCEDIYNNFKTVEDQKLFENDITEKVKKLGFNSNEVEIVILNKYIILCLPINDVNIYIIGDENDNEIILHEIIQTVEKALNNITNNQIGKRQLIDKLDSVYLILDEIADSGIIMETNPNVIINRLYMHEGDLQEHTPLNQAISSAKENIIRSLLSGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLC2</accession>
    <name>A0A1J1GLC2_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chorein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00091200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526030.1">
        <property type="nucleotide sequence ID" value="XM_028671688.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLC2"/>
    <dbReference type="GeneID" id="39729436"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00091200"/>
    <dbReference type="OrthoDB" id="369649at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="527" mass="62377" checksum="5312467E36340675" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLD9</accession>
    <name>A0A1J1GLD9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Rad50/SbcC-type AAA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00072500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000004">
        <property type="protein sequence ID" value="CRG93021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028525843.1">
        <property type="nucleotide sequence ID" value="XM_028674856.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729250"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00072500"/>
    <dbReference type="OMA" id="FMCHRSL"/>
    <dbReference type="OrthoDB" id="10072614at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048018">
        <property type="term" value="F:receptor ligand activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37458">
        <property type="entry name" value="THISBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37458:SF1">
        <property type="entry name" value="THISBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rad50/SbcC-type AAA" evidence="3">
        <location>
            <begin position="193"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="16"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="75"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="391"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="481"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="903"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="16"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="37"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="87"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1496" mass="175993" checksum="1367B9BEC553FEA1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLK9</accession>
    <name>A0A1J1GLK9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00091500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000014">
        <property type="protein sequence ID" value="CRG93211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526033.1">
        <property type="nucleotide sequence ID" value="XM_028671721.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729439"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00091500"/>
    <dbReference type="OMA" id="EWLYFHY"/>
    <dbReference type="OrthoDB" id="392374at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45912">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45912:SF3">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="2211"/>
            <end position="2228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="2266"/>
            <end position="2286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2436"/>
            <end position="2470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3782"/>
            <end position="3801"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2573"/>
            <end position="2624"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3261"/>
            <end position="3295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2442"/>
            <end position="2453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="2454"/>
            <end position="2467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="3786"/>
            <end position="3801"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="4219" mass="506889" checksum="76F30E0B801EA07B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLP5</accession>
    <name>A0A1J1GLP5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00094900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526065.1">
        <property type="nucleotide sequence ID" value="XM_028672076.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLP5"/>
    <dbReference type="GeneID" id="39729473"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00094900"/>
    <dbReference type="OrthoDB" id="370029at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056352">
        <property type="entry name" value="Microp_apicomplexa_13"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23523">
        <property type="entry name" value="Microp_apicomplexa_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="109" mass="13017" checksum="E30CB5E7931FE098" modified="2017-02-15" version="1">MNIKKRLIKEVENFRRTVLLRGSPAFKIGVWFSGLTIGLTWILFSEYNQPKTNNLFFKKKEADIFTNDEIEKWNKPYFSNDNQNLLIKDSKLTVDEKRKIILKDIYKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLU9</accession>
    <name>A0A1J1GLU9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00109500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526212.1">
        <property type="nucleotide sequence ID" value="XM_028673710.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLU9"/>
    <dbReference type="GeneID" id="39729621"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00109500"/>
    <dbReference type="OrthoDB" id="361216at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="351" mass="42087" checksum="62A1E0967ED47E52" modified="2017-02-15" version="1">MENIIYRKNIITFLILIILLKNSFTFNLHREHSMGYVIVFKYNKLRNNVSITHSNFLRCKRNNKLNVMERSVDKVTGHFMKDKELFLEVDKKQKMIEEIEKMKVFDYDNVKKYLDVLSENDVYEEIINHKIHLYKKYNEKEKQNHIIKMQNFLNPYIVNLRKKKAKEKVEYLISRLITGDNVDQIIMEMFKKKLIDVYVLTFIDDKIIEAHSKLVKNDKLNSGEEMSISEKILRTLKDRIIAQEKLNKKGTFNFTRILFLSTTLDMNENREPLIKSIIKSIDELEEFELYLLDALEYAEDNEKMKKYIPHMELLLNTCKKMNPIHNQFLNKQSENIKFFPDNVDTSHLKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GLX8</accession>
    <name>A0A1J1GLX8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sulfhydryl oxidase</fullName>
            <ecNumber evidence="6">1.8.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ERV1</name>
        <name evidence="8" type="ORF">PGAL8A_00106100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 R'C(R)SH + O2 = R'C(R)S-S(R)CR' + H2O2</text>
            <dbReference type="Rhea" id="RHEA:17357"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:16520"/>
            <dbReference type="ChEBI" id="CHEBI:17412"/>
            <dbReference type="EC" id="1.8.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.3.2" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526178.1">
        <property type="nucleotide sequence ID" value="XM_028673333.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GLX8"/>
    <dbReference type="GeneID" id="39729587"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00106100"/>
    <dbReference type="OMA" id="FALWMCQ"/>
    <dbReference type="OrthoDB" id="17199at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016971">
        <property type="term" value="F:flavin-dependent sulfhydryl oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.310">
        <property type="entry name" value="ERV/ALR sulfhydryl oxidase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039799">
        <property type="entry name" value="ALR/ERV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036774">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017905">
        <property type="entry name" value="ERV/ALR_sulphydryl_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12645">
        <property type="entry name" value="ALR/ERV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12645:SF0">
        <property type="entry name" value="FAD-LINKED SULFHYDRYL OXIDASE ALR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04777">
        <property type="entry name" value="Evr1_Alr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69000">
        <property type="entry name" value="FAD-dependent thiol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51324">
        <property type="entry name" value="ERV_ALR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 6" id="KW-0274">FAD</keyword>
    <keyword evidence="2 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERV/ALR sulfhydryl oxidase" evidence="7">
        <location>
            <begin position="31"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU371123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG93356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="138" mass="16430" checksum="D4330BB96981C9D4" modified="2017-02-15" version="1">MDIEKCYENSCKDRGKIKIFENKNDTKKTIYPPDRAEIGRASWLILHTISANYPDQPTEEEKLKHTKFFYAFSNLYPCHICKLDLLHILKKYQLNCQNRVSYSTFIFNLHNMINEEIGKDIYPCDNIQNIIDKYKTKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMH7</accession>
    <name>A0A1J1GMH7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00127100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000017">
        <property type="protein sequence ID" value="CRG93564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526386.1">
        <property type="nucleotide sequence ID" value="XM_028674791.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GMH7"/>
    <dbReference type="GeneID" id="39729796"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00127100"/>
    <dbReference type="OrthoDB" id="361479at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2130.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="687"/>
            <end position="718"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="868" mass="102616" checksum="6A7695A716BEFEDC" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMJ5</accession>
    <name>A0A1J1GMJ5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GYF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00133000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526447.1">
        <property type="nucleotide sequence ID" value="XM_028674858.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729855"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00133000"/>
    <dbReference type="OMA" id="MWHKMSE"/>
    <dbReference type="OrthoDB" id="48509at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003169">
        <property type="entry name" value="GYF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035445">
        <property type="entry name" value="GYF-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02213">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00444">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55277">
        <property type="entry name" value="GYF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50829">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GYF" evidence="2">
        <location>
            <begin position="1472"/>
            <end position="1520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="529"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="621"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="824"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1864"/>
            <end position="1913"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1939"/>
            <end position="2109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2236"/>
            <end position="2272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="529"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="635"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="836"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1878"/>
            <end position="1909"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1939"/>
            <end position="1984"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1985"/>
            <end position="1996"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1998"/>
            <end position="2015"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2023"/>
            <end position="2109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2237"/>
            <end position="2256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2374" mass="278885" checksum="E91396EF25A4766E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMS8</accession>
    <name>A0A1J1GMS8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Rhoptry protein ROP14, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ROP14</name>
        <name evidence="11" type="ORF">PGAL8A_00141900</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the lipase maturation factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526535.1">
        <property type="nucleotide sequence ID" value="XM_028674955.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729943"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00141900"/>
    <dbReference type="OMA" id="KMQEHNM"/>
    <dbReference type="OrthoDB" id="434126at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22265">
        <property type="entry name" value="UDM1_RNF168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009613">
        <property type="entry name" value="LMF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057433">
        <property type="entry name" value="LMF1/2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057434">
        <property type="entry name" value="LMF1/2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14463">
        <property type="entry name" value="LIPASE MATURATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14463:SF10">
        <property type="entry name" value="LIPASE MATURATION FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06762">
        <property type="entry name" value="LMF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25179">
        <property type="entry name" value="LMF1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="66"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="124"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="272"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="297"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="456"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="482"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="512"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="537"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="568"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="domain" description="Lipase maturation factor 1/2 N-terminal" evidence="9">
        <location>
            <begin position="180"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="Lipase maturation factor 1/2 C-terminal" evidence="10">
        <location>
            <begin position="601"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="846"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="965"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1090"/>
            <end position="1254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1266"/>
            <end position="1312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1090"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1113"/>
            <end position="1127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1128"/>
            <end position="1145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1146"/>
            <end position="1165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1166"/>
            <end position="1185"/>
        </location>
    </feature>
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        <location>
            <begin position="1186"/>
            <end position="1205"/>
        </location>
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        <location>
            <begin position="1213"/>
            <end position="1223"/>
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            <begin position="1224"/>
            <end position="1246"/>
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            <begin position="1266"/>
            <end position="1297"/>
        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00005512"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF06762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF25179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG93713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1426" mass="172635" checksum="DC8BFB590A3C6E4A" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GMU4</accession>
    <name>A0A1J1GMU4_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FPL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00147400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526590.1">
        <property type="nucleotide sequence ID" value="XM_028675017.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729998"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00147400"/>
    <dbReference type="OMA" id="DDQIFQY"/>
    <dbReference type="OrthoDB" id="294052at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
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        <property type="entry name" value="CLEC16A/TT9"/>
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    </dbReference>
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        </location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
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            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG93768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1504" mass="181447" checksum="E301988B26507BA4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNB8</accession>
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        <submittedName>
            <fullName evidence="4">CPW-WPC family protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00158500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526698.1">
        <property type="nucleotide sequence ID" value="XM_028675137.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNB8"/>
    <dbReference type="GeneID" id="39730110"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00158500"/>
    <dbReference type="OMA" id="FAWKCEV"/>
    <dbReference type="OrthoDB" id="361898at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006387">
        <property type="entry name" value="CPW_WPC_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01492">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09717">
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    </dbReference>
    <dbReference type="SMART" id="SM01099">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
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            <begin position="23"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="CPW-WPC" evidence="3">
        <location>
            <begin position="122"/>
            <end position="182"/>
        </location>
    </feature>
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            <begin position="36"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
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            <position position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG93877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="208" mass="24436" checksum="C391D05C0B50D128" modified="2017-02-15" version="1" fragment="single">MKHMSIFFLSFFFFFISPSIKCYKNFCFSFLSVKSNKNISKDLNELYNINEELVANEKEDEDDEEEELENSNFDHIAHKNLENAEEQATIDLENAEIENLLDDEIFKIIQERLKKLWYIGKCRRDYSSICPLEWKISSYDENLCIPPDTYDGQCRSIDFSNSTSADKELFAWKCEVEWPCVDSPKLKVLDKCPMRWLSVGNNLCVAPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="28" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNQ0</accession>
    <name>A0A1J1GNQ0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA-binding protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00378600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_028670119.1"/>
    </dbReference>
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    <dbReference type="GeneID" id="39732316"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00378600"/>
    <dbReference type="OMA" id="YKGVQNM"/>
    <dbReference type="OrthoDB" id="5970at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050441">
        <property type="entry name" value="RBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48034">
        <property type="entry name" value="TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="20"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="161"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="164"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="250" mass="30287" checksum="3542E5662D921395" modified="2017-02-15" version="1">MNFKDAKKESEDRNHKNDGSTLYVSNLSSKITTAKLQDIFEKFGNIEKCYVISNPITRESRNFGFVTFNSSHEAHNALSKANKMEVEGRIINVEIAKRNEPHEPTPGEYKGVQNMMKRNGIRHDFYGKKYDRSYDKRRYESRRANPYNKEHIKSFSYRNNSYRNYDKYGRNKYSDYRNYDRRSNDNKYHRKNEYYKRNNRSSDDEKGYSRDENKKKKRYEKNRKSSSSSNSERRRYRNSPINRSPRYRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNU4</accession>
    <name>A0A1J1GNU4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00385500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526972.1">
        <property type="nucleotide sequence ID" value="XM_028670195.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GNU4"/>
    <dbReference type="GeneID" id="39732385"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00385500"/>
    <dbReference type="OrthoDB" id="10253869at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031956">
        <property type="term" value="F:medium-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201:SF32">
        <property type="entry name" value="2-SUCCINYLBENZOATE--COA LIGASE, CHLOROPLASTIC_PEROXISOMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43201">
        <property type="entry name" value="ACYL-COA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="586" mass="70125" checksum="AD75F1AB6AE53A90" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GNZ3</accession>
    <name>A0A1J1GNZ3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00391100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527028.1">
        <property type="nucleotide sequence ID" value="XM_028670258.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732441"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00391100"/>
    <dbReference type="OrthoDB" id="386089at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="230"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="762"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="820"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="978"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1555"/>
            <end position="1575"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1602"/>
            <end position="1633"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="438"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="762"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="776"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="820"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="855"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1001"/>
            <end position="1015"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1602"/>
            <end position="1613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1614"/>
            <end position="1627"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2132" mass="251989" checksum="181723BAA35AD2D3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP53</accession>
    <name>A0A1J1GP53_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">U3 snoRNA-associated small subunit rRNA processing protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00389300</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527010.1">
        <property type="nucleotide sequence ID" value="XM_028670238.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP53"/>
    <dbReference type="GeneID" id="39732423"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00389300"/>
    <dbReference type="OrthoDB" id="674604at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034511">
        <property type="term" value="F:U3 snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000480">
        <property type="term" value="P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000472">
        <property type="term" value="P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013934">
        <property type="entry name" value="Utp13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19854">
        <property type="entry name" value="TRANSDUCIN BETA-LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19854:SF15">
        <property type="entry name" value="TRANSDUCIN BETA-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08625">
        <property type="entry name" value="Utp13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="528"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="639"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="681"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="domain" description="U3 small nucleolar RNA-associated protein 13 C-terminal" evidence="8">
        <location>
            <begin position="1010"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="955"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="319"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1097" mass="130450" checksum="9D3E92436A75674C" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GP89</accession>
    <name>A0A1J1GP89_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Translation machinery-associated protein 7, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">TMA7</name>
        <name evidence="2" type="ORF">PGAL8A_00393300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000022">
        <property type="protein sequence ID" value="CRG94229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527050.1">
        <property type="nucleotide sequence ID" value="XM_028670282.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GP89"/>
    <dbReference type="GeneID" id="39732463"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00393300"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015157">
        <property type="entry name" value="TMA7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09072">
        <property type="entry name" value="TMA7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="54" mass="6140" checksum="616B32D7DDD35234" modified="2017-02-15" version="1">MPLNVQGGKKKPLKAPKKGTTEITEEEKSFKKEMAEKKKAEEEAKQKLLKAKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPN8</accession>
    <name>A0A1J1GPN8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-f protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00186800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000025">
        <property type="protein sequence ID" value="CRG94473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527292.1">
        <property type="nucleotide sequence ID" value="XM_028670551.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPN8"/>
    <dbReference type="GeneID" id="39730395"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00186800"/>
    <dbReference type="OMA" id="ELFMNIN"/>
    <dbReference type="OrthoDB" id="1490254at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="584" mass="69965" checksum="A3986C082D324761" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPR6</accession>
    <name>A0A1J1GPR6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00182600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527255.1">
        <property type="nucleotide sequence ID" value="XM_028670509.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPR6"/>
    <dbReference type="GeneID" id="39730353"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00182600"/>
    <dbReference type="OMA" id="FMAANFK"/>
    <dbReference type="OrthoDB" id="387671at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="557"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="667"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="75"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="332"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="513"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="566"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="672"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="682"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="701"/>
            <end position="953"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1051" mass="128547" checksum="B413EEE5396A449E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GPY7</accession>
    <name>A0A1J1GPY7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Splicing factor 3A subunit 1, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">SF3A1</name>
        <name evidence="9" type="ORF">PGAL8A_00196800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527388.1">
        <property type="nucleotide sequence ID" value="XM_028670658.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GPY7"/>
    <dbReference type="GeneID" id="39730495"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00196800"/>
    <dbReference type="OMA" id="VKYQEQQ"/>
    <dbReference type="OrthoDB" id="447637at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045292">
        <property type="term" value="P:mRNA cis splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000381">
        <property type="term" value="P:regulation of alternative mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.790:FF:000001">
        <property type="entry name" value="Splicing factor 3a, subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.790">
        <property type="entry name" value="Surp module"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045146">
        <property type="entry name" value="SF3A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022030">
        <property type="entry name" value="SF3A1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000061">
        <property type="entry name" value="Surp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035967">
        <property type="entry name" value="SWAP/Surp_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15316">
        <property type="entry name" value="SPLICEOSOME ASSOCIATED PROTEIN 114/SWAP SPLICING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15316:SF1">
        <property type="entry name" value="SPLICING FACTOR 3A SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12230">
        <property type="entry name" value="PRP21_like_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01805">
        <property type="entry name" value="Surp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00648">
        <property type="entry name" value="SWAP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109905">
        <property type="entry name" value="Surp module (SWAP domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50128">
        <property type="entry name" value="SURP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="SURP motif" evidence="8">
        <location>
            <begin position="44"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="SURP motif" evidence="8">
        <location>
            <begin position="182"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="567"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="590" mass="70158" checksum="3D41B13FFBFD958B" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ31</accession>
    <name>A0A1J1GQ31_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">PGAL8A_00192900</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the DEAD box helicase family. eIF4A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="CVMV01000029">
        <property type="protein sequence ID" value="CRG94531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527346.1">
        <property type="nucleotide sequence ID" value="XM_028670611.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ31"/>
    <dbReference type="GeneID" id="39730454"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00192900"/>
    <dbReference type="OMA" id="TRFHDFK"/>
    <dbReference type="OrthoDB" id="10265785at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000089">
        <property type="entry name" value="Eukaryotic initiation factor 4A-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000031">
        <property type="entry name" value="Eukaryotic initiation factor 4A-III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 16" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="15">
        <location>
            <begin position="17"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="48"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="229"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="11">
        <location>
            <begin position="17"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="CRG94531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="390" mass="44777" checksum="2A486051F0D2FAEE" modified="2017-02-15" version="1">MEKDDYYKSSEKYEICTSFENIGIDEGLLRGIYAYGFEKPSAIQQRGIKPILSGRDVILQSQSGTGKTCVFALGALNCVNRNLNETQVIILSPTRELAEQTQKVCLALADYIHVTIYCCIGGKKISDDIKALNNGVHIISGTPGRIYHMLNLRHLKCKYIKQLVIDEADEMLNKGFKEQVYDIYRFLSPNTQIILSSATLPQEVLEITNKFMHKPVKILVKRDELTLEGIKQFFVSIEKEQWKYETLADLYESLTITQAVVFCNTKLKVDWLTKKMLESNFTVCKMHAGMSQSERDDIMLKFRQCKFRVLISTDIWGRGLDVQEVSLVVNYDLPNSRESYIHRIGRSGRFGRKGVAINFVKNDDIKILRDIEQYYSTQIDEMPMNITELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQ74</accession>
    <name>A0A1J1GQ74_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Mediator of RNA polymerase II transcription subunit 31</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00196300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the Mediator complex subunit 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527383.1">
        <property type="nucleotide sequence ID" value="XM_028670652.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQ74"/>
    <dbReference type="GeneID" id="39730490"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00196300"/>
    <dbReference type="OMA" id="NYWRTKP"/>
    <dbReference type="OrthoDB" id="10257739at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1340">
        <property type="entry name" value="Mediator of RNA polymerase II, submodule Med31 (Soh1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038089">
        <property type="entry name" value="Med31_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008831">
        <property type="entry name" value="Mediator_Med31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13186">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05669">
        <property type="entry name" value="Med31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0010">Activator</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="129" mass="16317" checksum="726387FE9721E761" modified="2017-02-15" version="1">MENKITEILNKEENKKLLILYKNFKESSFENKLRFECELEFVQSLSNIEYIKYLYENKYFDDKKFLNYLKYLNYWRSKPYIFYIHFPICLYVLEILNDNKVHEYFKNSNSFNNFIYYLKLHWLYFSYQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQD0</accession>
    <name>A0A1J1GQD0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">60S ribosomal export protein NMD3, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">NMD3</name>
        <name evidence="3" type="ORF">PGAL8A_00095600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000015">
        <property type="protein sequence ID" value="CRG93250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526072.1">
        <property type="nucleotide sequence ID" value="XM_028672154.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQD0"/>
    <dbReference type="GeneID" id="39729480"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00095600"/>
    <dbReference type="OrthoDB" id="203821at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039768">
        <property type="entry name" value="Nmd3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007064">
        <property type="entry name" value="Nmd3_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12746:SF2">
        <property type="entry name" value="60S RIBOSOMAL EXPORT PROTEIN NMD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12746">
        <property type="entry name" value="NONSENSE-MEDIATED MRNA DECAY PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04981">
        <property type="entry name" value="NMD3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nmd3 N-terminal" evidence="2">
        <location>
            <begin position="242"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="573"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="573"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="752" mass="88313" checksum="E8F8CDA8EBD40FD6" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQD6</accession>
    <name>A0A1J1GQD6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Plasmodium RESA N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00187600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000025">
        <property type="protein sequence ID" value="CRG94481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527299.1">
        <property type="nucleotide sequence ID" value="XM_028670559.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQD6"/>
    <dbReference type="GeneID" id="39730403"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00187600"/>
    <dbReference type="OMA" id="FITKEAY"/>
    <dbReference type="OrthoDB" id="10603273at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.180">
        <property type="entry name" value="Plasmodium RESA, N-terminal helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019111">
        <property type="entry name" value="PRESA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044885">
        <property type="entry name" value="PRESA_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09687">
        <property type="entry name" value="PRESAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="Plasmodium RESA N-terminal" evidence="2">
        <location>
            <begin position="96"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="216" mass="25665" checksum="6695C7FC2208D3F1" modified="2017-02-15" version="1">MQNYSINSFQKRGYTIKEIKYHNFILSRIFSVSFLFLLFLFLHDSHNHLNMICLEFQFKHIFSRKLAELNAQENDERFEEVPGFNGDNSSNSTSFGSVSSAELMSLWNDMRLQKERKLNDTLSSLLDELNMRANFYGISDSKINDMWSFITKEAYIKVIQINQKIDDKLSIITTDGSCTFENKQKFIWEANFTWNHLIYCIERRFFRCFSNLNLMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQH9</accession>
    <name>A0A1J1GQH9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Plasmodium RESA N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00194300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000030">
        <property type="protein sequence ID" value="CRG94546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527361.1">
        <property type="nucleotide sequence ID" value="XM_028670627.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQH9"/>
    <dbReference type="GeneID" id="39730469"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00194300"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="332" mass="39952" checksum="2EFAA7802E3C25B0" modified="2017-02-15" version="1">MKSHKVKTNNLEKGPLVTSYVRTNELSYNFFGYMDIATEKRSSIKRMFSGTFIISLIIFFYIFLQYEHELLRNDIKKQYYNEYHSRIFAEKKGFFKKKKKEVSYYLEKKIFEDELNGYYENKRIIMLGMFFSMKEELLHSPQLDRIPDFIKHEIWDVWSYFSHIFISQLELKEQEDIRNIEENGYLHTETVNLCKEMTEKWFNMRLKLTNIYVRFLHYSFMIWKYDKSRAHVSVTSKGRVKLLHDGILGMPGMELIRLPDGNLRIQERESESSSDSSERVTRKPVQESLDALKNSLEIPRIQDQNLEEEEEPIEENRSTRCSCFGNLFRRCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQL6</accession>
    <name>A0A1J1GQL6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Early transcribed membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ETRAMP</name>
        <name evidence="2" type="ORF">PGAL8A_00195100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527371.1">
        <property type="nucleotide sequence ID" value="XM_028670638.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQL6"/>
    <dbReference type="GeneID" id="39730478"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00195100"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1330">
        <property type="entry name" value="Plasmodium falciparum UIS3 membrane protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006389">
        <property type="entry name" value="Early_transc_mb_plasmodium"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038403">
        <property type="entry name" value="PfUIS3_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01495">
        <property type="entry name" value="ETRAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09716">
        <property type="entry name" value="ETRAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="266" mass="31079" checksum="392D38FF823128F6" modified="2017-02-15" version="1">MRVSKILFFLSFFLVFNLLKICLYANQISSKNYSYLNKNNYEIKKKKKKKILSICLGISLAAAAAAIGIGFYMYKKGSNRRGRMLDFPDHDEEIKHENDKKKDLEYENFKEIVINKIKNEFDNLNDNEKINIINNDDYIRNIIGKLSLDKNVSLEKDVQKRLINDVNLSLKNKFLSFLNNNRNVNVLLNIEKAAHEELLKRFHKSDDKQKHLMIYNNKIVVNAVKSAATDRGLILSVDELNPITNNVFTRLEPTFDIFLRNRSKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQX9</accession>
    <name>A0A1J1GQX9_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">transketolase</fullName>
            <ecNumber evidence="6">2.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">PGAL8A_00139300</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = aldehydo-D-ribose 5-phosphate + D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:10508"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="16">Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="15">Binds 1 thiamine pyrophosphate per subunit. During the reaction, the substrate forms a covalent intermediate with the cofactor.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the transketolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.1" evidence="6"/>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526509.1">
        <property type="nucleotide sequence ID" value="XM_028674927.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQX9"/>
    <dbReference type="GeneID" id="39729917"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00139300"/>
    <dbReference type="OMA" id="ADYMRGS"/>
    <dbReference type="OrthoDB" id="10267175at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004802">
        <property type="term" value="F:transketolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07033">
        <property type="entry name" value="TPP_PYR_DXS_TK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02012">
        <property type="entry name" value="TPP_TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.920:FF:000011">
        <property type="entry name" value="Transketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000004">
        <property type="entry name" value="Transketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000045">
        <property type="entry name" value="Transketolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055152">
        <property type="entry name" value="Transketolase-like_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005478">
        <property type="entry name" value="Transketolase_bac-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020826">
        <property type="entry name" value="Transketolase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033247">
        <property type="entry name" value="Transketolase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00232">
        <property type="entry name" value="tktlase_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43522">
        <property type="entry name" value="TRANSKETOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43522:SF2">
        <property type="entry name" value="TRANSKETOLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22613">
        <property type="entry name" value="Transketolase_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00456">
        <property type="entry name" value="Transketolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00802">
        <property type="entry name" value="TRANSKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0106">Calcium</keyword>
    <keyword evidence="10 16" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 15" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="18">
        <location>
            <begin position="355"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="13">
        <location>
            <position position="412"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="116"/>
            <end position="118"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="358"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="385"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="438"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="462"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="470"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="474"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="521"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="17">
        <location>
            <position position="28"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="17">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR605478-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="CRG93687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="669" mass="75685" checksum="4853F7D98B0F3EF7" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQY1</accession>
    <name>A0A1J1GQY1_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fam-a protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00222900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527647.1">
        <property type="nucleotide sequence ID" value="XM_028670945.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQY1"/>
    <dbReference type="GeneID" id="39730756"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00222900"/>
    <dbReference type="OMA" id="WDENGTK"/>
    <dbReference type="OrthoDB" id="370643at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006486">
        <property type="entry name" value="PYST_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01599">
        <property type="entry name" value="PYST-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG94832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="258" mass="30042" checksum="5081300666C15DAE" modified="2017-02-15" version="1">MNNAENNHTNEISDRLNQMSHLICNHKSEIMKVNEIITEAVDVLYNFAVNDEDYYKYSTIDEHSNLYFKKVNNTEVGKIELIFPDTSKLEKIIGIIWDENGARNFDPHFIEGKIIRIYDQNLILVQQSYKGTLGKEGRYFYILAHKKKINKNTYLIACLSLNINDNNKKCNIPFTNPFINSANSFTLDIECDEKIKNSSLRKMHINLSGYFIKREESYIKLTYISSIDLGTSSLIPQFIIRKIKANKMLLLNLLRKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="33" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQY7</accession>
    <name>A0A1J1GQY7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Elongation factor 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00210300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527521.1">
        <property type="nucleotide sequence ID" value="XM_028670805.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQY7"/>
    <dbReference type="GeneID" id="39730630"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00210300"/>
    <dbReference type="OMA" id="DSMESAW"/>
    <dbReference type="OrthoDB" id="364892at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01681">
        <property type="entry name" value="aeEF2_snRNP_like_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04096">
        <property type="entry name" value="eEF2_snRNP_like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01885">
        <property type="entry name" value="EF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16261">
        <property type="entry name" value="EF2_snRNP_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000010">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000006">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.240:FF:000003">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000002">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000058">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF10">
        <property type="entry name" value="EUKARYOTIC TRANSLATION ELONGATION FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="7">
        <location>
            <begin position="17"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG94706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="832" mass="93504" checksum="FADEAD9EF3B40319" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQZ4</accession>
    <name>A0A1J1GQZ4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00208100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527499.1">
        <property type="nucleotide sequence ID" value="XM_028670781.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQZ4"/>
    <dbReference type="GeneID" id="39730608"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00208100"/>
    <dbReference type="OMA" id="TASWFIC"/>
    <dbReference type="OrthoDB" id="368515at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="74" mass="8924" checksum="63F416F182201CD6" modified="2017-02-15" version="1">MEENNSKNEASKIMKLQRSLSMGLYFVCISTLSWFICTTKRRKEWADIMLDYVHHKRCSFLSNSWEKFLKRLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GQZ8</accession>
    <name>A0A1J1GQZ8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00140900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526525.1">
        <property type="nucleotide sequence ID" value="XM_028674944.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GQZ8"/>
    <dbReference type="GeneID" id="39729933"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00140900"/>
    <dbReference type="OMA" id="AMEPQKS"/>
    <dbReference type="OrthoDB" id="370529at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:peptidyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1470">
        <property type="entry name" value="Peptidyl-tRNA hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001328">
        <property type="entry name" value="Pept_tRNA_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036416">
        <property type="entry name" value="Pept_tRNA_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01195">
        <property type="entry name" value="Pept_tRNA_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG93703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="234" mass="28001" checksum="427FCA59674B45E6" modified="2017-02-15" version="1">MISKSRILIALGNEIKKNSVSNFKKGDVSRMYLDYLNRKYNFDEWIKLSNINSYICEKNDIILIKPIISIFEKSGTLIKNILSYLNYADTKNICIIIPDFYRSVGTYKYKSYVKIHEKLGSDFYNILNSNIINNINSCNYLQLCLGINNLQKQEKKSTHFNFLEPIDEHEYKKFLKTFELADEYFNKKILNSHYITTNYIQFKKKYSAMEPQKHFKKDTSKRRYILDIYKHMYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GR98</accession>
    <name>A0A1J1GR98_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Biotin protein ligase, putative</fullName>
            <ecNumber evidence="4">6.3.4.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00219300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the biotin--protein ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.14" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527611.1">
        <property type="nucleotide sequence ID" value="XM_028670905.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GR98"/>
    <dbReference type="GeneID" id="39730720"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00219300"/>
    <dbReference type="OMA" id="CQIKWIN"/>
    <dbReference type="OrthoDB" id="10250105at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004075">
        <property type="term" value="F:biotin carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004077">
        <property type="term" value="F:biotin--[biotin carboxyl-carrier protein] ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004408">
        <property type="entry name" value="Biotin_CoA_COase_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00121">
        <property type="entry name" value="birA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12835">
        <property type="entry name" value="BIOTIN PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12835:SF5">
        <property type="entry name" value="BIOTIN--PROTEIN LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03099">
        <property type="entry name" value="BPL_LplA_LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="3">
        <location>
            <begin position="23"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG94796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="282" mass="32718" checksum="01690E1BF877A75D" modified="2017-02-15" version="1">MEEKILFEKYYHEYNAFRLHFNILDSTQLYCKRNMKLFLESGKLKNDNMIIVSCDSQTKGIGTRDTKENVDRMWLSEKGNIFTTFVFLWDKKNLEKTSCLAQTSTVAVSKTLEFYNLKTQIKWINDVLINNKKLAGCLVNLHYLDDSSLDNYVCIMVGIGVNVELIDDKNILNNNFTSIKKELEEDFNNPSSIPSVEDVMEKLIENFHLAINQLYNEGFSSLLDYISLRLLYREKKVLIDQDNNKIFGYLKGLANDGSILLLDDNNQTINVNNGHLFPYEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRB5</accession>
    <name>A0A1J1GRB5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fam-f protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00153300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526645.1">
        <property type="nucleotide sequence ID" value="XM_028675077.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRB5"/>
    <dbReference type="GeneID" id="39730057"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00153300"/>
    <dbReference type="OMA" id="TAISWFL"/>
    <dbReference type="OrthoDB" id="387072at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012113935" description="Fam-f protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG93824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="564" mass="67150" checksum="02FFF849D74ECDB5" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRB9</accession>
    <name>A0A1J1GRB9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00223900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527657.1">
        <property type="nucleotide sequence ID" value="XM_028670956.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730766"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00223900"/>
    <dbReference type="OMA" id="YIYAIID"/>
    <dbReference type="OrthoDB" id="372450at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="685"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="712"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="768"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1315"/>
            <end position="1338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2387"/>
            <end position="2409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2563"/>
            <end position="2583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="910"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="952"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1357"/>
            <end position="1377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="910"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="958"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1365"/>
            <end position="1377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG94842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2706" mass="326641" checksum="181E238C413EC419" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRD2</accession>
    <name>A0A1J1GRD2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MYND finger protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00130700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526424.1">
        <property type="nucleotide sequence ID" value="XM_028674832.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRD2"/>
    <dbReference type="GeneID" id="39729832"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00130700"/>
    <dbReference type="OMA" id="MMLQMDS"/>
    <dbReference type="OrthoDB" id="341421at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="216"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="56"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG93602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="254" mass="29853" checksum="3993CA363B80AE98" modified="2017-02-15" version="1">MAEDILKSVHSNFKYVLISCDINNEVKELNFKGSEEKFQNTLASYFRRIIFNEKGKNELKETIKEKLESNKEENKENKEKDDLNKISPDIINNAIETSQTYQIIPLTLPTEENDYYAVNCYIDDVGRIKQLPYNSRASRICNTDIYGDAFLSKTYDNEDFKRCDFTIKEYEEFLKNPPKSANRWDQAQAMQDLLSQMKSKKDGDNLNISNTKINKCENCYEEKNLKRCGKCKKVYYCSIECQKNDFVFHKRICS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRE1</accession>
    <name>A0A1J1GRE1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SDE2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00131500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000019">
        <property type="protein sequence ID" value="CRG93610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028526432.1">
        <property type="nucleotide sequence ID" value="XM_028674841.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRE1"/>
    <dbReference type="GeneID" id="39729840"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00131500"/>
    <dbReference type="OMA" id="NPLMNEK"/>
    <dbReference type="OrthoDB" id="392591at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053822">
        <property type="entry name" value="SDE2-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22782">
        <property type="entry name" value="SDE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="SDE2-like" evidence="2">
        <location>
            <begin position="275"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG93610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="421" mass="50635" checksum="C9024D36BFDE93EA" modified="2017-02-15" version="1">MTSNYIIHIGNKIINKRIKIKEFLNKYERKVLEKNVNVFFYILINLLFNLSIDRFRLVINRKYIFFKNRKRIDIVFNITKKLLTLNNIDIKEKITNLIENKKNCIDNSEINENELYEDINTKRNNFSNTSLVDNIYKEYRKLNIKNEKDYLNNKSETLLNNQEKFFDKKLFYENYTFENKSNYINYYENFKSDHLDNKVLFSSNLLNYKDVKNKINDFKIKSNEEYHKNKNILEQKVSNNKYDKKSIILIKKEKKTNINIFDEFLDIYLLFRLKGGKGGFGANLRVKKRKKKKKNNFDAARNLKGNRILVDRIIETSEILLKKKEQEQILIDKLNSSFIINETDENDHLLKNHIIKDEINENSSKSENFIKDNQKLDMRHIIANGIKEEKKQKKNLKKKIDKNVNNQIKNVKSIENMYNFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRE8</accession>
    <name>A0A1J1GRE8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Signal peptidase complex catalytic subunit SEC11</fullName>
            <ecNumber evidence="4">3.4.21.89</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Signal peptidase complex catalytic subunit sec11</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">SP21</name>
        <name evidence="16" type="ORF">PGAL8A_00243500</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.</text>
            <dbReference type="EC" id="3.4.21.89"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase S26B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.89" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527850.1">
        <property type="nucleotide sequence ID" value="XM_028671171.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRE8"/>
    <dbReference type="GeneID" id="39730963"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00243500"/>
    <dbReference type="OMA" id="GSMEPFM"/>
    <dbReference type="OrthoDB" id="10257561at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005787">
        <property type="term" value="C:signal peptidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009003">
        <property type="term" value="F:signal peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019758">
        <property type="entry name" value="Pept_S26A_signal_pept_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015927">
        <property type="entry name" value="Peptidase_S24_S26A/B/C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001733">
        <property type="entry name" value="Peptidase_S26B"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02228">
        <property type="entry name" value="sigpep_I_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10806">
        <property type="entry name" value="SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10806:SF6">
        <property type="entry name" value="SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00717">
        <property type="entry name" value="Peptidase_S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00728">
        <property type="entry name" value="SIGNALPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="LexA/Signal peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00761">
        <property type="entry name" value="SPASE_I_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="143"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="167"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S24/S26A/S26B/S26C" evidence="15">
        <location>
            <begin position="56"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="CRG95037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="184" mass="21276" checksum="F57EA59C5428384E" modified="2017-02-15" version="1">MDFLKEQYNTFMLDLKKTFRNTRDGISHVLNVICLLLNALMIWKLLVIFTGCESPVVVVLSGSMEPGYYRGDTLSLYYPNKIHAGDVVVYQINGRDIPIVHRILNMHVSKDDKFHILSKGDNNNIDDRGLYEPNQYWLENEHVLGLSVGYTPYIGILTIWINEYPSVKWFIVSVMLLMILLGYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRI3</accession>
    <name>A0A1J1GRI3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Kelch protein K13, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00254800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527956.1">
        <property type="nucleotide sequence ID" value="XM_028671289.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRI3"/>
    <dbReference type="GeneID" id="39731076"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00254800"/>
    <dbReference type="OMA" id="YFQEYKN"/>
    <dbReference type="OrthoDB" id="191037at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051260">
        <property type="term" value="P:protein homooligomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18316">
        <property type="entry name" value="BTB_POZ_KCTD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.120.10.80:FF:000058">
        <property type="entry name" value="Kelch protein K13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.710.10:FF:000115">
        <property type="entry name" value="Kelch protein K13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003131">
        <property type="entry name" value="T1-type_BTB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46344:SF27">
        <property type="entry name" value="KELCH REPEAT SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46344">
        <property type="entry name" value="OS02G0202900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02214">
        <property type="entry name" value="BTB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00501">
        <property type="entry name" value="KELCHREPEAT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="BTB" evidence="4">
        <location>
            <begin position="330"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="221"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG95143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="706" mass="81839" checksum="3A08B4CC43555538" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GRU0</accession>
    <name>A0A1J1GRU0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcription factor with AP2 domain(S), putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ApiAP2</name>
        <name evidence="1" type="ORF">PGAL8A_00262000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528028.1">
        <property type="nucleotide sequence ID" value="XM_028671369.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GRU0"/>
    <dbReference type="GeneID" id="39731149"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00262000"/>
    <dbReference type="OrthoDB" id="372114at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="457" mass="54086" checksum="002531678B259B1B" modified="2017-02-15" version="1">MNMNDFCDNRKSCLKKKKKIEKCYNVWESIFSKTTGCSKDEIRKKVAKRKRDKERLLSILYGSVFKGRKYLLYSRKWRGKTLSEIINQDKKNYLNLKHLKNVDNSYFCKLAIGYVDQNDKNYFKKNGENVFMKNEVNTMKKVQPTFNNTTNKRKGTHIEKSGTNNDIEEVYDRLNFLEKRSYKNKYKDNNNLSMNYPYNNRLPNDKCYEDNSDESKVVKYKYLPTGVFYSRVSKSFIANWIDDKTKKQIKIPYKISEFGVEKCMILAILSRNLRISNLNNVLKYYDNLTLDQKEKMLQAIRTTQKSEKLFNEILKQNNKDITNIVNSNNVVSKNNESDQKNISLKKNLIEKKKIKQSYNNSEKLPTGVYFYQGSYVANWWETNQKKQFKVPFKISEYGITRAKNLAIISRLIRSSSAQEVNLLLTQMEQNKNITKLNYTTISNLAFKYIKNQPKKDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GS46</accession>
    <name>A0A1J1GS46_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Protein FAM33A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PGAL8A_00006900</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
            <location evidence="2">Kinetochore</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Spindle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SKA2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528114.1">
        <property type="nucleotide sequence ID" value="XM_028671464.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GS46"/>
    <dbReference type="GeneID" id="39728591"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00006900"/>
    <dbReference type="OrthoDB" id="193920at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000940">
        <property type="term" value="C:outer kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005876">
        <property type="term" value="C:spindle microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026762">
        <property type="entry name" value="Ska2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042091">
        <property type="entry name" value="Ska2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32017">
        <property type="entry name" value="SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32017:SF3">
        <property type="entry name" value="SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11362">
        <property type="entry name" value="DUF3161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16740">
        <property type="entry name" value="SKA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-0132">Cell division</keyword>
    <keyword evidence="12" id="KW-0137">Centromere</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="7" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8" id="KW-0498">Mitosis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ska2 N-terminal" evidence="14">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="15">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF16740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG95303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="305" mass="35836" checksum="76B57851605F6573" modified="2017-02-15" version="1" fragment="single">FLNMNGDIELIERKLKDELCKIYEDDINPLLILNDFENIKNELNKINKELDSLYIKKKLSINYLHRQMQNYNFLLNLENNLNISSKEFNNYHNSEIILNNFFYDNIRKFLMNINYDEIKELIYISNYHKTIEKEIYSNGKLNGIYDEAKNSKNISLDSNFSKNNVDNNESKENIKILDNENTVDENKIGKAHHENDINNLFIPINQDTFQSVPVLIRRRAKLEDVNLIYKTLYDMAIKKGSCHPVEKSELTNMNLQVFGQTGEAKIATLRYLKIIEVINKTGSVRLLNCAGIKKKKKKKKTWLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSF6</accession>
    <name>A0A1J1GSF6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fam-h protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00265400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000034">
        <property type="protein sequence ID" value="CRG95451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528262.1">
        <property type="nucleotide sequence ID" value="XM_028671628.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSF6"/>
    <dbReference type="GeneID" id="39731183"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00265400"/>
    <dbReference type="OMA" id="REKINRX"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="216" mass="24853" checksum="FBCA1163CCA712A0" modified="2017-02-15" version="1">MRNLIISNVTSKSRNNTHIAENFIIEDISTSRKYHAKGKINKFIFFIKVFLFTLLNTQRSWNEKCSIKNNLNLGGKRFLAENKEITELTNDELKTRLSDLLKTLEEKNTKDSNVQSDVVQGKVETIEIENENSVSRKEKSNKKINSRDLMEKYKKCMRLFNLASIIILPILSMTVSIVALSTSEKTYINISNIITSLYLVLNSILLSDLRSNKDNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GSF7</accession>
    <name>A0A1J1GSF7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00018600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528228.1">
        <property type="nucleotide sequence ID" value="XM_028671591.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GSF7"/>
    <dbReference type="GeneID" id="39728708"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00018600"/>
    <dbReference type="OMA" id="NSNMFYV"/>
    <dbReference type="OrthoDB" id="5970at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="193" mass="22653" checksum="C02C1E9054847974" modified="2017-02-15" version="1">MNQILNSNATIICKNIPIDINHGPLLGEGIYFGKKKSGMFFIKYVHFKDAIKAYESLKNNKICEHDFKLSFSKNDEIKYKALKGNKKAIIELKNIYNKNEESKTNNDISIDIINELNEQNNELLKKKKKEKEIEKKKDKSFILNLLTKTDEIQINEQDIKEELKNYINLNCLCSYDFDENNKYDNYLTPIFPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTC1</accession>
    <name>A0A1J1GTC1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="5">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">PGAL8A_00294300</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 20">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HRD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528546.1">
        <property type="nucleotide sequence ID" value="XM_028671944.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTC1"/>
    <dbReference type="GeneID" id="39731476"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00294300"/>
    <dbReference type="OMA" id="ANLTMFT"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16479">
        <property type="entry name" value="RING-H2_synoviolin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000564">
        <property type="entry name" value="ERAD-associated E3 ubiquitin-protein ligase HRD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050731">
        <property type="entry name" value="HRD1_E3_ubiq-ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057992">
        <property type="entry name" value="TPR_SYVN1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058051">
        <property type="entry name" value="Znf_RING_synoviolin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22763:SF184">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SYNOVIOLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22763">
        <property type="entry name" value="RING ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25563">
        <property type="entry name" value="TPR_SYVN1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="14 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="12" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 15" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="179"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="215"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="17">
        <location>
            <begin position="298"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="CRG95738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="508" mass="59883" checksum="B4964CB50D076CCC" modified="2017-02-15" version="1">MEINMRLYIFLSHVGLAFILMYSFIKYGEFYSSVVYLSTEKFPKTIIYNFLLMIFIVFCKLLLNIFIGELRYLEVEQLIDNARAFIMDTILFLVLSKPTINGKEVSSIILIKYLSIIVILKAYHLVLYSRVSHIFELGVPRTRVLVRLFIFMCLLSVANLTMFTYFYKYSLKNSTMYLWLFFESLSIFESCQISIFKFFVNIIDLRSPNGLPSKATILFFLDILHDIMSLIIFLVFIIVFILNNFSNLPLHMTADIIHVVKTLISRFKSFQRYRELTKNIESKFIDATEEEIREVGTCIICRDDLKEGSKKLSCSHIFHVECLKSWFIQQQTCPICRNEIKPYTNTKNKNNDTNEIEKKEEKLNHISVTEIIHKAPFLPNEDSPYLNDVYPMNNFNLKEENYDCFKQNIDLKERIKILSDLCDYYKELSLACLKEIDKINHTTVPANIMLRNIYGSLNYNILNNTEENEIQKYLNKISHIPQMDVFKNYLEKILITDMKYIKDICALI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTT0</accession>
    <name>A0A1J1GTT0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Obg-like ATPase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">PGAL8A_00184300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000023">
        <property type="protein sequence ID" value="CRG94451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527272.1">
        <property type="nucleotide sequence ID" value="XM_028670528.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTT0"/>
    <dbReference type="GeneID" id="39730370"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00184300"/>
    <dbReference type="OMA" id="VLRCFDN"/>
    <dbReference type="OrthoDB" id="424823at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04867">
        <property type="entry name" value="TGS_YchF_OLA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01900">
        <property type="entry name" value="YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.300:FF:000001">
        <property type="entry name" value="Ribosome-binding ATPase YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000001">
        <property type="entry name" value="Ribosome-binding ATPase YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.300">
        <property type="entry name" value="TGS-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00944">
        <property type="entry name" value="YchF_OLA1_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004396">
        <property type="entry name" value="ATPase_YchF/OLA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023192">
        <property type="entry name" value="TGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013029">
        <property type="entry name" value="YchF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041706">
        <property type="entry name" value="YchF_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00092">
        <property type="entry name" value="redox-regulated ATPase YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305">
        <property type="entry name" value="OBG GTPASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23305:SF11">
        <property type="entry name" value="OBG-LIKE ATPASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06071">
        <property type="entry name" value="YchF-GTPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006641">
        <property type="entry name" value="CHP00092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="TGS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="4">
        <location>
            <begin position="21"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="5">
        <location>
            <begin position="301"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="30"/>
            <end position="35"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="CRG94451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="392" mass="45164" checksum="F562E36AAB45E871" modified="2017-02-15" version="1">MAPKKKEEEQKILLGRPKNTLKMGLVGLPNVGKSTTFNVLTKLNIPAENYPFCTIDPHEAKVTVEDDRFDWLVNHFKPKSSVHAYLSIFDIAGLVKNAHLGEGLGNNFLSNIAAVDGIYHVVRAFENEDIIHTEGNINPVRDMEIINSELIYKDISHCEKNLEEINKVLNRNKKDKIKQNEHDVLTGVLKHLKENKWIKDGNWKNSEVEVINDFNFLTAKPVVYLVNMSEEDFIRQKNKYLAKIYNWVQENNKGTIIPYCAEFEQKILNMTEEEKIDYFKQKNIKQSMLNKIIKTGYYEINLIHFFTCGQDEVKCWTIRKGTKAPQAAGVIHTDFEKGFICAEVYKYTDLVEHKSESEVKANGKYLQKGKDYIVEDGDIVFFKFNVSSSGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTW3</accession>
    <name>A0A1J1GTW3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mitochondrial import inner membrane translocase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">TIM10</name>
        <name evidence="11" type="ORF">PGAL8A_00313500</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Heterohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Mitochondrion inner membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
            <orientation evidence="9">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="9">The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the small Tim family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528730.1">
        <property type="nucleotide sequence ID" value="XM_028672148.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTW3"/>
    <dbReference type="GeneID" id="39731668"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00313500"/>
    <dbReference type="OMA" id="VGENMQK"/>
    <dbReference type="OrthoDB" id="274922at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045039">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.810">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit tim13 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004217">
        <property type="entry name" value="Tim10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035427">
        <property type="entry name" value="Tim10-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11038">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11038:SF16">
        <property type="entry name" value="MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02953">
        <property type="entry name" value="zf-Tim10_DDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144122">
        <property type="entry name" value="Tim10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="8 9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Tim10-like" evidence="10">
        <location>
            <begin position="17"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU367043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CRG95922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="75" mass="8503" checksum="5BBB122927B8D9BC" modified="2017-02-15" version="1">MNDNISKVNSTIVELLGMSDLFKRMQNVCWGKCIPDVNDPFLSVGETSCVDRCVHKYMEIHTLVGKNLQESQITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GTX6</accession>
    <name>A0A1J1GTX6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00317700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528772.1">
        <property type="nucleotide sequence ID" value="XM_028672194.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GTX6"/>
    <dbReference type="GeneID" id="39731710"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00317700"/>
    <dbReference type="OMA" id="TIAIYMH"/>
    <dbReference type="OrthoDB" id="372975at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="968" mass="114606" checksum="C5480E899B092A33" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU64</accession>
    <name>A0A1J1GU64_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Chitinase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">CHT1</name>
        <name evidence="7" type="ORF">PGAL8A_00321200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyl hydrolase 18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000048">
        <property type="protein sequence ID" value="CRG95999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528807.1">
        <property type="nucleotide sequence ID" value="XM_028672235.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU64"/>
    <dbReference type="ABCD" id="A0A1J1GU64">
        <property type="antibodies" value="1 sequenced antibody"/>
    </dbReference>
    <dbReference type="GeneID" id="39731745"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00321200"/>
    <dbReference type="OMA" id="VDIDWEP"/>
    <dbReference type="OrthoDB" id="76388at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001579">
        <property type="entry name" value="Glyco_hydro_18_chit_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00704">
        <property type="entry name" value="Glyco_hydro_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01095">
        <property type="entry name" value="GH18_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012046046" evidence="5">
        <location>
            <begin position="21"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="6">
        <location>
            <begin position="107"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG95999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="587" mass="67828" checksum="E8B53FE1BF079A00" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GU95</accession>
    <name>A0A1J1GU95_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00324400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000051">
        <property type="protein sequence ID" value="CRG96031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528839.1">
        <property type="nucleotide sequence ID" value="XM_028672270.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GU95"/>
    <dbReference type="GeneID" id="39731777"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00324400"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="136" mass="16556" checksum="B66454B8B508C39D" modified="2017-02-15" version="1">MKAFTLCLKIFTFLILTWIFHCFYNYDSSMSLINKDTMQIANRIKHERLLAEAGVLEKKQTNIKERKEYYPSDEKNNKDEKLVYFKRMFNMWCIAITLLMYELFCKKTNEMNNEYRYQMLNINRNNNSQPHELPIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUD1</accession>
    <name>A0A1J1GUD1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein YIPF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00231600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Golgi apparatus membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the YIP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527733.1">
        <property type="nucleotide sequence ID" value="XM_028671040.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUD1"/>
    <dbReference type="GeneID" id="39730843"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00231600"/>
    <dbReference type="OMA" id="KASFSYI"/>
    <dbReference type="OrthoDB" id="440385at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048280">
        <property type="term" value="P:vesicle fusion with Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045231">
        <property type="entry name" value="Yip1/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006977">
        <property type="entry name" value="Yip1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21236">
        <property type="entry name" value="GOLGI MEMBRANE PROTEIN YIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21236:SF2">
        <property type="entry name" value="PROTEIN YIPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04893">
        <property type="entry name" value="Yip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="276"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="Yip1" evidence="8">
        <location>
            <begin position="159"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="107"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG94919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="294" mass="34175" checksum="DB57B4E6B0B386BC" modified="2017-02-15" version="1">MNYYNQKLINRVNKNENDTSFVNENHLNNPHINKKIFENNYKPNLIPNIPYENNLYQNNLVAKNFNYTNSDNNDLLTNPFSNQSYINNEINKNNDIFNNYTITNKNDLNKNNKKENEQDQEEEEEELPLLEELGINFDLISKRMKSVFMFYKIDHSLFENSDLSGPLLIVLSLGFILLLAGKASFSYIYLIGIVSSLSIYLLLNMMSQNLTLDLYRTISMLGYALLPLVILSIISILINLRSKKGYSISFFCILWSALTASRFFEVALCMNSQRYLVAYPIFLLYSCFALIIIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUF4</accession>
    <name>A0A1J1GUF4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Variant-silencing SET protein, putative</fullName>
            <ecNumber evidence="14">2.1.1.43</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">SETvs</name>
        <name evidence="14" type="ORF">PGAL8A_00234100</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.43" evidence="14"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527757.1">
        <property type="nucleotide sequence ID" value="XM_028671067.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39730868"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00234100"/>
    <dbReference type="OrthoDB" id="308383at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10531">
        <property type="entry name" value="SET_SETD2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050777">
        <property type="entry name" value="SET2_Histone-Lys_MeTrsfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22884">
        <property type="entry name" value="SET DOMAIN PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 14" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SET" evidence="13">
        <location>
            <begin position="2261"/>
            <end position="2382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="148"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="184"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="358"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="859"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="2036"/>
            <end position="2068"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="1049"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="2119"/>
            <end position="2146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="185"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="261"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="285"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="362"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="378"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="575"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="728"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="860"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="2036"/>
            <end position="2046"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="CRG94943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2687" mass="317078" checksum="5C58AEFA32C564B8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUH2</accession>
    <name>A0A1J1GUH2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00209400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG94697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527512.1">
        <property type="nucleotide sequence ID" value="XM_028670795.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUH2"/>
    <dbReference type="GeneID" id="39730621"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00209400"/>
    <dbReference type="OMA" id="CFRACSM"/>
    <dbReference type="OrthoDB" id="370856at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="19"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG94697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="125" mass="14901" checksum="CF471E58AC19122E" modified="2017-02-15" version="1">MISHNNDFAGLNSLRTKNISEISELIKEAKENKKNLNIDCNEGENIEHLKIFAENQGNCFSICKNNLIKRFEKDIEEYKNFSYKNNININEENIKKLESDYKYLENQFCFYVCSKKYFHLLQDNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="34" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GUU7</accession>
    <name>A0A1J1GUU7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Endopeptidase, putative</fullName>
            <ecNumber evidence="8">3.4.24.59</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00247900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.59" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000032">
        <property type="protein sequence ID" value="CRG95080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028527893.1">
        <property type="nucleotide sequence ID" value="XM_028671219.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GUU7"/>
    <dbReference type="GeneID" id="39731007"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00247900"/>
    <dbReference type="OMA" id="QYYRNML"/>
    <dbReference type="OrthoDB" id="17530at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006518">
        <property type="term" value="P:peptide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804:SF79">
        <property type="entry name" value="MITOCHONDRIAL INTERMEDIATE PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M3A/M3B catalytic" evidence="7">
        <location>
            <begin position="360"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M3A/M3B catalytic" evidence="7">
        <location>
            <begin position="673"/>
            <end position="884"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG95080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="921" mass="109851" checksum="AF608FACFBD92E90" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV10</accession>
    <name>A0A1J1GV10_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">60S ribosomal protein L35, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00351600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529103.1">
        <property type="nucleotide sequence ID" value="XM_028672563.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV10"/>
    <dbReference type="GeneID" id="39732046"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00351600"/>
    <dbReference type="OMA" id="VMNQKAR"/>
    <dbReference type="OrthoDB" id="528635at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000463">
        <property type="term" value="P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.310:FF:000002">
        <property type="entry name" value="60S ribosomal protein L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00374">
        <property type="entry name" value="Ribosomal_uL29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001854">
        <property type="entry name" value="Ribosomal_uL29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018254">
        <property type="entry name" value="Ribosomal_uL29_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045059">
        <property type="entry name" value="Ribosomal_uL29_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036049">
        <property type="entry name" value="Ribosomal_uL29_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00012">
        <property type="entry name" value="L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45722">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45722:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL29-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00831">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46561">
        <property type="entry name" value="Ribosomal protein L29 (L29p)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00579">
        <property type="entry name" value="RIBOSOMAL_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="4"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="124" mass="14786" checksum="C6964AAB0D7543F9" modified="2017-02-15" version="1">MSNLKAFELRSLKKKELLEKLEELKKELSGLRISKAIGNSAKNSKIRSVRKNVARVLTVYNQKKKTELKNKYKGKRFKPYNLRKKLTKNKRLQLTDKQKKAMTLREKKKSLNFPKRKYLVVHRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="29" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV24</accession>
    <name>A0A1J1GV24_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">WD repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">PGAL8A_00353200</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529119.1">
        <property type="nucleotide sequence ID" value="XM_028672581.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV24"/>
    <dbReference type="GeneID" id="39732062"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00353200"/>
    <dbReference type="OMA" id="CNNKYNT"/>
    <dbReference type="OrthoDB" id="4096at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000234">
        <property type="term" value="P:positive regulation of rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045943">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053826">
        <property type="entry name" value="WDR75"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44215">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 75"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44215:SF1">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 75"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101908">
        <property type="entry name" value="Putative isomerase YbhE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="620"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="628"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="673"/>
            <end position="696"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG96314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1170" mass="140050" checksum="1911AAB92B11CD0E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV28</accession>
    <name>A0A1J1GV28_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00359900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529180.1">
        <property type="nucleotide sequence ID" value="XM_028672649.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV28"/>
    <dbReference type="GeneID" id="39732129"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00359900"/>
    <dbReference type="OMA" id="YFYDFPF"/>
    <dbReference type="OrthoDB" id="392906at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13146">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13146:SF3">
        <property type="entry name" value="EAMA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="296"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="332"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="569"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="596"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="627"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="691"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="911"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="968"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="999"/>
            <end position="1017"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1029"/>
            <end position="1049"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1067" mass="126432" checksum="B884D677F28D03BF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="36" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GV62</accession>
    <name>A0A1J1GV62_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Tudor staphylococcal nuclease, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">TSN</name>
        <name evidence="9" type="ORF">PGAL8A_00363900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529220.1">
        <property type="nucleotide sequence ID" value="XM_028672693.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GV62"/>
    <dbReference type="GeneID" id="39732169"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00363900"/>
    <dbReference type="OMA" id="ARCADHH"/>
    <dbReference type="OrthoDB" id="10023235at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031332">
        <property type="term" value="C:RNAi effector complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031047">
        <property type="term" value="P:regulatory ncRNA-mediated gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.140:FF:000018">
        <property type="entry name" value="Serine/threonine-protein kinase 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.90:FF:000037">
        <property type="entry name" value="Tudor staphylococcal nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.90">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016685">
        <property type="entry name" value="Silence_cplx_Nase-comp_TudorSN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035437">
        <property type="entry name" value="SNase_OB-fold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016071">
        <property type="entry name" value="Staphylococal_nuclease_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002999">
        <property type="entry name" value="Tudor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12302">
        <property type="entry name" value="EBNA2 BINDING PROTEIN P100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12302:SF2">
        <property type="entry name" value="STAPHYLOCOCCAL NUCLEASE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00565">
        <property type="entry name" value="SNase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00567">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017179">
        <property type="entry name" value="RISC-Tudor-SN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00318">
        <property type="entry name" value="SNc"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00333">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50199">
        <property type="entry name" value="Staphylococcal nuclease"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50830">
        <property type="entry name" value="TNASE_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50304">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="TNase-like" evidence="8">
        <location>
            <begin position="2"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="TNase-like" evidence="8">
        <location>
            <begin position="598"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="domain" description="Tudor" evidence="7">
        <location>
            <begin position="821"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="199"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="466"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="785"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="199"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="209"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="219"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="484"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR017179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG96415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="999" mass="117459" checksum="1D87F0E5BB950FDB" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="32" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVG4</accession>
    <name>A0A1J1GVG4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Carbonic anhydrase, putative</fullName>
            <ecNumber evidence="5">4.2.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">CA</name>
        <name evidence="5" type="ORF">PGAL8A_00367500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529255.1">
        <property type="nucleotide sequence ID" value="XM_028672731.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVG4"/>
    <dbReference type="GeneID" id="39732205"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00367500"/>
    <dbReference type="OMA" id="SHWRVIS"/>
    <dbReference type="OrthoDB" id="429145at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.200.10">
        <property type="entry name" value="Alpha carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001148">
        <property type="entry name" value="CA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036398">
        <property type="entry name" value="CA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023561">
        <property type="entry name" value="Carbonic_anhydrase_a-class"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18952">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18952:SF276">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_53, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00194">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01057">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51069">
        <property type="entry name" value="Carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51144">
        <property type="entry name" value="ALPHA_CA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012249878" evidence="3">
        <location>
            <begin position="25"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="618"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-carbonic anhydrase" evidence="4">
        <location>
            <begin position="217"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="637" mass="74997" checksum="8CBF0D0DD6BF181E" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVJ8</accession>
    <name>A0A1J1GVJ8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00008100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000033">
        <property type="protein sequence ID" value="CRG95314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528125.1">
        <property type="nucleotide sequence ID" value="XM_028671476.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVJ8"/>
    <dbReference type="GeneID" id="39728603"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00008100"/>
    <dbReference type="OMA" id="FWIHNLV"/>
    <dbReference type="OrthoDB" id="345648at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG95314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="433" mass="51592" checksum="5195181BE6788CD1" modified="2017-02-15" version="1">MNGSEILREKKKNQNKNFESSYEICNADEIQEFYQTEFIDSSNEEFLPNKSLLKNKEYSIYLDKKKKNYENKLKMEKEISFQNEMLKNILISSQKMKEMQKELFKVDVQNFIPILPPESRNSYSIQREYTGMYDNINQCCQYNNYNNNKNINHNYYNKCESNIDTNEDIPRNYLSGNIEKCSESKLISYPSRIGEIKVNIDDIKKGLLSYYSNIFSLEQYDIEDRINILRYGEKNISDSLNIKYSYLKKEIPKNPQFLYYNSELNNPYSSIYQNIPPEYYYSYHSDKNTNYLKDDIVKSNENCYSEKTQNEKSVFEGNFDHQGQISELLNSLKNKCEDAKFRVEHLSSKFNKKYENPDNKFWIHNLVPPHLRKPGLNDEDDIRKHLVTVYAQLFNEAMLNKKKITALEKKLHILKLKSKIYKNQCKIETRNAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="31" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVN0</accession>
    <name>A0A1J1GVN0_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Dynein light intermediate chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00419000</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Cytoplasm</location>
            <location evidence="1 10">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the dynein light intermediate chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529414.1">
        <property type="nucleotide sequence ID" value="XM_028672908.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVN0"/>
    <dbReference type="GeneID" id="39732722"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00419000"/>
    <dbReference type="OMA" id="PYNIISD"/>
    <dbReference type="OrthoDB" id="27603at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005813">
        <property type="term" value="C:centrosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045504">
        <property type="term" value="F:dynein heavy chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008467">
        <property type="entry name" value="Dynein1_light_intermed_chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022780">
        <property type="entry name" value="Dynein_light_int_chain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12688">
        <property type="entry name" value="DYNEIN LIGHT INTERMEDIATE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12688:SF0">
        <property type="entry name" value="DYNEIN LIGHT INTERMEDIATE CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05783">
        <property type="entry name" value="DLIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7 10" id="KW-0243">Dynein</keyword>
    <keyword evidence="4 10" id="KW-0493">Microtubule</keyword>
    <keyword evidence="8 10" id="KW-0505">Motor protein</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="180"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="656"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="203"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="214"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="239"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="250"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="659"/>
            <end position="677"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG96610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="709" mass="84230" checksum="4ACFA97E0B18EBCD" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVN2</accession>
    <name>A0A1J1GVN2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00374200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529322.1">
        <property type="nucleotide sequence ID" value="XM_028672806.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732272"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00374200"/>
    <dbReference type="OMA" id="YICRYIG"/>
    <dbReference type="OrthoDB" id="372452at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="699"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1092"/>
            <end position="1115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1919"/>
            <end position="2110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2402"/>
            <end position="2444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="699"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1919"/>
            <end position="1957"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1964"/>
            <end position="1996"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2008"/>
            <end position="2091"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2098"/>
            <end position="2107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2411"/>
            <end position="2444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2645" mass="311399" checksum="DC76C70FC0CAE2A4" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVQ1</accession>
    <name>A0A1J1GVQ1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase</fullName>
            <ecNumber evidence="7">2.1.1.205</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">2'-O-ribose RNA methyltransferase TRM7 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">PGAL8A_00421400</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>cytidine(32)/guanosine(34) in tRNA + 2 S-adenosyl-L-methionine = 2'-O-methylcytidine(32)/2'-O-methylguanosine(34) in tRNA + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:42396"/>
            <dbReference type="Rhea" id="RHEA-COMP:10246"/>
            <dbReference type="Rhea" id="RHEA-COMP:10247"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74445"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.205"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.205" evidence="7"/>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529438.1">
        <property type="nucleotide sequence ID" value="XM_028672935.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVQ1"/>
    <dbReference type="GeneID" id="39732746"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00421400"/>
    <dbReference type="OMA" id="YVCKPQS"/>
    <dbReference type="OrthoDB" id="289250at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106340">
        <property type="term" value="F:tRNA (guanosine(34)-2'-O)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002128">
        <property type="term" value="P:tRNA nucleoside ribose methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01547">
        <property type="entry name" value="RNA_methyltr_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03162">
        <property type="entry name" value="RNA_methyltr_E_TRM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028590">
        <property type="entry name" value="RNA_methyltr_E_TRM7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050082">
        <property type="entry name" value="RNA_methyltr_RlmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002877">
        <property type="entry name" value="RNA_MeTrfase_FtsJ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015507">
        <property type="entry name" value="rRNA-MeTfrase_E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10920">
        <property type="entry name" value="RIBOSOMAL RNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10920:SF12">
        <property type="entry name" value="TRNA (CYTIDINE(32)_GUANOSINE(34)-2'-O)-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01728">
        <property type="entry name" value="FtsJ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Ribosomal RNA methyltransferase FtsJ" evidence="9">
        <location>
            <begin position="21"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal RNA methyltransferase FtsJ" evidence="9">
        <location>
            <begin position="143"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="344"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="348"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="388"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="266"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG96634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="643" mass="75920" checksum="62BDE9285C0362EE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVV2</accession>
    <name>A0A1J1GVV2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00361400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529195.1">
        <property type="nucleotide sequence ID" value="XM_028672665.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVV2"/>
    <dbReference type="GeneID" id="39732144"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00361400"/>
    <dbReference type="OMA" id="FYVSYFS"/>
    <dbReference type="OrthoDB" id="376721at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012068588" evidence="2">
        <location>
            <begin position="24"/>
            <end position="1267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="553"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="553"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="586"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="634"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="788"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="815"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="840"/>
            <end position="852"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1267" mass="151918" checksum="01F430334DABBF5D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GVX7</accession>
    <name>A0A1J1GVX7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00428600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529510.1">
        <property type="nucleotide sequence ID" value="XM_028673015.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GVX7"/>
    <dbReference type="GeneID" id="39732818"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00428600"/>
    <dbReference type="OMA" id="YKRVEVP"/>
    <dbReference type="OrthoDB" id="360147at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="190" mass="22632" checksum="2CCC71A159AE8E69" modified="2017-02-15" version="1">MIFKSVKYLSNKVCDVLVSFGVRQNKTTFISHPGVMVVSQLLEMKLITRPRAKLTQENVNAMVEFDYELAKKAQIAVDNNLPINFFDLEYIDRPEYLKLLLEEKEILEKAREDVLKREKGNYKMPDILKNYKRVEIPRKWRQELEIDEKILNEQPGLKENIELQKIMHNYIQNKFKNKKIEETPKKHIKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW10</accession>
    <name>A0A1J1GW10_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PIR-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00268600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000038">
        <property type="protein sequence ID" value="CRG95484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528293.1">
        <property type="nucleotide sequence ID" value="XM_028671663.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW10"/>
    <dbReference type="GeneID" id="39731216"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00268600"/>
    <dbReference type="OrthoDB" id="10622804at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG95484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="329" mass="37472" checksum="28DED2F1B76C0C36" modified="2017-02-15" version="1">MFSYSGVIVYIFFFLILIFQYFCNKSFEISNKNLNIVSNLIGARVLTEQQLSQIIRTVRSSSDKPDILVELPEFTQEVLFGMSGKLSSNFTGDNTVEYTTWMSNKNIDIVRALNTHPEPNNKSNLNNFVYLWSKLAEDFILYTKVFSIYEVMLNGRISNNEPHIIPVLSSKFTPLSSTTSSSTYSSSITPATSAISSLVNNNLSEIVTNISSISTSLFKKLLTLTPSIETETIITSENNSSLLMPVEHSNLYKECFWFFCNPKNFIALYIPLVVVGRLLFFIYLYNHTHIRSVLGENNPKKEKGKRRMHKMDNGYNIHENSELPDIDPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="23" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW32</accession>
    <name>A0A1J1GW32_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ADP-ribosylation factor, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00433300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529556.1">
        <property type="nucleotide sequence ID" value="XM_028673066.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW32"/>
    <dbReference type="GeneID" id="39732865"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00433300"/>
    <dbReference type="OMA" id="HIVDRNC"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="29"/>
            <end position="36"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG96752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="189" mass="22290" checksum="EF47607078A1962D" modified="2017-02-15" version="1">MGNKIITFFRDCCNKLFNRKIIFQIRICGPAQSGKTTFVKYLLYNKFLKVKPTEGLFVEKIDFEEFSVIIWDSRYNIEDDVSINRIDIDAVIYFIDVSDRGRLKIAKKGFYKILQDFSHIDDFLILASKQDKKNCMLLEHIRKELKIDQIVDKNCHLAECSSKTGYGIDSSMNWLFNQLMIKRKKKLCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GW37</accession>
    <name>A0A1J1GW37_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00423100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529455.1">
        <property type="nucleotide sequence ID" value="XM_028672953.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GW37"/>
    <dbReference type="GeneID" id="39732763"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00423100"/>
    <dbReference type="OrthoDB" id="374708at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="363"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="393"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="426" mass="51148" checksum="A910C83ACCD4C1E3" modified="2017-02-15" version="1">MFFFSFFLYKVIFYLNLFYFCFNENFEKIKYPQDLTKIKYYESYNKIDKKYLYKHVGKPILQDIIISVKIEENEKEDKILYLPKKKNFLKIKGDWSEYPKDKIKMICIAFIQKNQLLSNEELKCPKDIFDSPTALSECYIENNFSIINLFLYIEISQINIEKLFSLYNIPVVINSDNYSKYFTNDKKKSKEQKPNLDLHLCYKSYNESPLYLGKVIFNAYPLNIQKNMDDYDVIYTKSFLTSNWDYNLFINGDYITIYNRVVFISFPREDNKNKKCAPFWDYGILGSGALNKIKKKDKNISSYEYVEYNFSNNIPNKYYIPFIKNDDLQTNENYLICLYSDENDFEGMELKNIHFYMNTTDSVILIFLIIFVIVFLPLIFSLTYLCVLVKMNILKIKMKKLQLLNRKDEIEEKLKKELNLDQYESI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWE6</accession>
    <name>A0A1J1GWE6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide repeat family protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00434500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529567.1">
        <property type="nucleotide sequence ID" value="XM_028673078.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39732877"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00434500"/>
    <dbReference type="OrthoDB" id="371503at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="892"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1512"/>
            <end position="1540"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="97"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="892"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="912"/>
            <end position="921"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1540" mass="184873" checksum="8C16F75A2505D9BF" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWJ2</accession>
    <name>A0A1J1GWJ2_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00426500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000070">
        <property type="protein sequence ID" value="CRG96685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529489.1">
        <property type="nucleotide sequence ID" value="XM_028672992.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWJ2"/>
    <dbReference type="GeneID" id="39732797"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00426500"/>
    <dbReference type="OrthoDB" id="360041at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012407683" evidence="2">
        <location>
            <begin position="22"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="586" mass="70394" checksum="6F468A8CEFCA6F22" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWN6</accession>
    <name>A0A1J1GWN6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00454300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529766.1">
        <property type="nucleotide sequence ID" value="XM_028673299.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWN6"/>
    <dbReference type="GeneID" id="39733076"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00454300"/>
    <dbReference type="OMA" id="DDCCYVR"/>
    <dbReference type="OrthoDB" id="369461at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="295" mass="35742" checksum="27BA68E46E3B5C48" modified="2017-02-15" version="1">MLKLQRKIFFLNYFNINVNNKNSLSTFKIFVHTEKNVIIQKNFENLLKFKDNVNTDIETVKKKYEVDNTFCSYITKRKKIFNLLSYNVKKYEENIFYKKSDGSENAFLYSNVIKPLKYCDRISDMLLINCFHNNSKTIIKKNLFDVLYKKCSLVYFFMDTKQINEMNKYLEDFEKNKKNFNIEHKINQDCFLKLKKKQKPIHIFYCYVSPYKFLLSNYFSKKISENLKSNYFDKKNFFFMNSKLSINDENALLLFRNNSLPSLLLFDEYCYIRYHIKGLFTNEASYYLFKVLLNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWX5</accession>
    <name>A0A1J1GWX5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Subpellicular microtubule protein 2, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">SPM2</name>
        <name evidence="1" type="ORF">PGAL8A_00452000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG96940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529743.1">
        <property type="nucleotide sequence ID" value="XM_028673273.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWX5"/>
    <dbReference type="GeneID" id="39733053"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00452000"/>
    <dbReference type="OMA" id="NIAPENY"/>
    <dbReference type="OrthoDB" id="389969at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG96940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="255" mass="29866" checksum="2AC66AFD15004C7A" modified="2017-02-15" version="1">MELSQYAGLSSERLDFLRNLDIRKRSVYNGSTFSYGNNIYEILHNCSDDQKSKKDGVFCPYDYKYPQKNRSFAGLESEIINDINMRNRRVKNDMNYRNDILKDIIQNNVEENEMNNSKYFFSDKGYALTPKRYLARHIDDSEISKYFSTKYAVTDKASGRTEIMVERKPGCSNIIVQNFSEFDAYVTFKKQGDKKNQEDSFVHTKMGIVPKNGLKNKKCKAQAIFTEALRYDNIAPDNYWMCPTIESEKKKKTKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GWY4</accession>
    <name>A0A1J1GWY4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Syntaxin, Qa-SNARE family, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00463700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529860.1">
        <property type="nucleotide sequence ID" value="XM_028673404.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GWY4"/>
    <dbReference type="GeneID" id="39733170"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00463700"/>
    <dbReference type="OMA" id="NRKMCII"/>
    <dbReference type="OrthoDB" id="10251371at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048278">
        <property type="term" value="P:vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15845">
        <property type="entry name" value="SNARE_syntaxin16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006012">
        <property type="entry name" value="Syntaxin/epimorphin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF224">
        <property type="entry name" value="HL02043P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00914">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="3">
        <location>
            <begin position="206"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="301" mass="35693" checksum="7CB50D85370023E4" modified="2017-02-15" version="1">MAMDIIFRNITNIYFDYRREIKKKKNRFKLSTYEKLDDEESGKEILLRQNEDIEMQKQIMLPPYWIEKIEECSEDINNIKSKLLDLQKLQKNKLLNVLNKDEKLTENITNMSADITFLIKNCEKKIQSISNDDEDDKNNLIEKLKKNAKHSLASQLQSLSQTFHRKQKIYIKEFRKLSNEYDQIESYQNFDGEEQLFYEKPNEVTSVNINKRNNDLKKIADTVIDLHNIFKELSVMLVDQGSLLDQIDYNIDITLDKSEQGLNKLKILQKRESDKKAKKCISFLTSLIFVLLILIIIKHLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXF5</accession>
    <name>A0A1J1GXF5_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DEK-C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00289300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000045">
        <property type="protein sequence ID" value="CRG95696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528504.1">
        <property type="nucleotide sequence ID" value="XM_028671897.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXF5"/>
    <dbReference type="GeneID" id="39731426"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00289300"/>
    <dbReference type="OMA" id="QLCINCS"/>
    <dbReference type="OrthoDB" id="361877at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014876">
        <property type="entry name" value="DEK_C"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51998">
        <property type="entry name" value="DEK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEK-C" evidence="2">
        <location>
            <begin position="5"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG95696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="225" mass="26069" checksum="5A2467FBB81A1956" modified="2017-02-15" version="1">MSVEDITTEQLENATKSFVSIESATQISRRYVRKKLEEIFNLEENALYERKKEINDIVEKVLTNLLEEENMKKNEGFSMKNEEVNNIKINDDKKENLDSKSNFINNNKDEIKEEIKNENNDNKSLCALSDEDKNSSKKRKKSSNDAVSTRKKQANIMTKEYFLNNAKSLFCNISENIKLKLEPRIFSTGSCGWHMMDKVYLLVGDHSVLCQFCINCSVIGSKQWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXP8</accession>
    <name>A0A1J1GXP8_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RNA-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00465100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529873.1">
        <property type="nucleotide sequence ID" value="XM_028673418.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXP8"/>
    <dbReference type="GeneID" id="39733184"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00465100"/>
    <dbReference type="OrthoDB" id="431068at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12254">
        <property type="entry name" value="RRM_hnRNPH_ESRPs_RBM12_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050666">
        <property type="entry name" value="ESRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13976">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5013357543" description="RNA-binding protein" evidence="4">
        <location>
            <begin position="23"/>
            <end position="1212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="636"/>
            <end position="664"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1212" mass="144636" checksum="1FB21A8EF1981BF7" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXQ7</accession>
    <name>A0A1J1GXQ7_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fam-g protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00329400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528885.1">
        <property type="nucleotide sequence ID" value="XM_028672321.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXQ7"/>
    <dbReference type="GeneID" id="39731823"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00329400"/>
    <dbReference type="OMA" id="KETFWEF"/>
    <dbReference type="OrthoDB" id="375954at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009618944" description="Fam-g protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG96080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="205" mass="25764" checksum="0B9F88D912472351" modified="2017-02-15" version="1">MLFLVLLYILLQCVSKLRNELPVKLQHDNFHSRTLIEYEHSEINNSKNEEYSIIIDREWKKEYNENRRCLYEIDKKLFWNWKKICIMNNIHYKWETERWNTWRELRNKMILKREEKNERDLTKFKNKNPNSNKIDLFIRKNKNSFKRFCKHIIKEWKIFLEKALKDWNEYKKQNATHGQQKKSDKIFKKYLKKYKTQIQKIKKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXS6</accession>
    <name>A0A1J1GXS6_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00494300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530166.1">
        <property type="nucleotide sequence ID" value="XM_028673744.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXS6"/>
    <dbReference type="GeneID" id="39733476"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00494300"/>
    <dbReference type="OrthoDB" id="365419at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="333" mass="40070" checksum="717CDCABEC73A6F4" modified="2017-02-15" version="1">MATKRLKLNYLSRNARYFNTSLIKSKIDILENYAKKNKLHKLKMDDLFEVFKLSKNEEDYKLSLHLLNIYYNFGRNLNTQQDVNLFFIFILRTKQLNEAKDFLKYFNGWLLCPPSNKYIILCMEEFFSKKKFYDVREIFSFVRQNSQIKLESSFYTITIKSMLMLKNNPIEESMIIYDDSYNMSIYLTNEVHNLLLEHNLFYYHNTREKKLENSRSLEFYEQNIRKIIIRLINELIKNRSSVQLSSKSLSLFAWANIYFDLKEIIKKSNNTFIDVEKCNSWFDIFKLSCLYNQMPQCYSGPFSEAFKNALEDMKNDKDAIKALEYVNIYFNED</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXT3</accession>
    <name>A0A1J1GXT3_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ADP-ribosylation factor GTPase-activating protein, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ARFGAP</name>
        <name evidence="8" type="ORF">PGAL8A_00465300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529875.1">
        <property type="nucleotide sequence ID" value="XM_028673420.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GXT3"/>
    <dbReference type="GeneID" id="39733186"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00465300"/>
    <dbReference type="OrthoDB" id="983479at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048205">
        <property type="term" value="P:COPI coating of Golgi vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08830">
        <property type="entry name" value="ArfGap_ArfGap1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45686:SF4">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45686">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00405">
        <property type="entry name" value="REVINTRACTNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Arf-GAP" evidence="7">
        <location>
            <begin position="6"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="310"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="310"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="348" mass="39845" checksum="27A8001DE9C5DCB7" modified="2017-02-15" version="1">MNPNAIELFNKLKREDESNNKCFDCRISNPDWVSVNHGIFLCINCSGVHRSMGVHISIVRSIKMDIFSDEQLKYMDKGGNKKFQTYLENYGISDFIPEKKYRTKAAEHYRKILRSIVHNSEPPSPLSLDEGKDIINYGINENINYNENNKNYNINEQNNYIPSINTSDIIENVSSTFSTLFNKASNITTNTINNINTNEIIETTKGTLISSGNWFTEKTKRIAENVSDSPWWTKSQNKIKDVTQNASGWISSISSTVSRSNSNLFFSNNNSNLKNNNMNTNEEINNTNNGNANFNNFSANNEYINYNSNNKNNFNRSNTSNSFKKGQSRNEFFNDAEETNWMSDSCKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GXZ8</accession>
    <name>A0A1J1GXZ8_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="15">DNA repair protein rhp16, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">PGAL8A_00471700</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529939.1">
        <property type="nucleotide sequence ID" value="XM_028673492.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733250"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00471700"/>
    <dbReference type="OMA" id="DHPYLIL"/>
    <dbReference type="OrthoDB" id="448448at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16448">
        <property type="entry name" value="RING-H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1740.10">
        <property type="entry name" value="Zinc finger, PARP-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001510">
        <property type="entry name" value="Znf_PARP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036957">
        <property type="entry name" value="Znf_PARP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF12">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01336">
        <property type="entry name" value="zf-PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50064">
        <property type="entry name" value="ZF_PARP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PARP-type" evidence="12">
        <location>
            <begin position="55"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="902"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="1334"/>
            <end position="1486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="826"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="716"/>
            <end position="757"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="CRG97136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1496" mass="175081" checksum="7273E73230473941" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY49</accession>
    <name>A0A1J1GY49_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chorein N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00480900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530033.1">
        <property type="nucleotide sequence ID" value="XM_028673596.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733342"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00480900"/>
    <dbReference type="OMA" id="YHNEYHN"/>
    <dbReference type="OrthoDB" id="378393at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39408">
        <property type="entry name" value="MUCIN-21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39408:SF3">
        <property type="entry name" value="MUCIN-21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="4309"/>
            <end position="4333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="4744"/>
            <end position="4767"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="4816"/>
            <end position="4836"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="4868"/>
            <end position="4896"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1182"/>
            <end position="1209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1592"/>
            <end position="1635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1799"/>
            <end position="1833"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3590"/>
            <end position="3609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="4006"/>
            <end position="4037"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2768"/>
            <end position="2795"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="4391"/>
            <end position="4431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1185"/>
            <end position="1204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1611"/>
            <end position="1627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1807"/>
            <end position="1829"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="3595"/>
            <end position="3609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="4014"/>
            <end position="4036"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="5267" mass="631704" checksum="9FCFE8042859EEF8" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY73</accession>
    <name>A0A1J1GY73_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00483400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000096">
        <property type="protein sequence ID" value="CRG97255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530057.1">
        <property type="nucleotide sequence ID" value="XM_028673623.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GY73"/>
    <dbReference type="GeneID" id="39733367"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00483400"/>
    <dbReference type="OMA" id="CNYDKQS"/>
    <dbReference type="OrthoDB" id="378548at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="366"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="521"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="109"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="369"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="387"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="407"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="417"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="437"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="535"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="545"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="599"/>
            <end position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="999" mass="120322" checksum="C28786A203E73850" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GY87</accession>
    <name>A0A1J1GY87_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00502100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530249.1">
        <property type="nucleotide sequence ID" value="XM_028673836.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733554"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00502100"/>
    <dbReference type="OMA" id="ETICILY"/>
    <dbReference type="OrthoDB" id="384723at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="959"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="997"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1240"/>
            <end position="1259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1274"/>
            <end position="1295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="339"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="558"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1085"/>
            <end position="1118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1327" mass="159279" checksum="F4E1B85CE3B75AA1" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYC3</accession>
    <name>A0A1J1GYC3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="5">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00503400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="5">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="5"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530262.1">
        <property type="nucleotide sequence ID" value="XM_028673850.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYC3"/>
    <dbReference type="GeneID" id="39733567"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00503400"/>
    <dbReference type="OMA" id="YMESVGI"/>
    <dbReference type="OrthoDB" id="193716at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001944">
        <property type="entry name" value="DEAD box helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="168"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="384"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="613" mass="72384" checksum="0EE427F79A82426F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYC4</accession>
    <name>A0A1J1GYC4_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transcription factor with AP2 domain(S), putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ApiAP2</name>
        <name evidence="9" type="ORF">PGAL8A_00513500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530363.1">
        <property type="nucleotide sequence ID" value="XM_028673962.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39733668"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00513500"/>
    <dbReference type="OrthoDB" id="384106at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00847">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="8">
        <location>
            <begin position="910"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1231"/>
            <end position="1316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1349"/>
            <end position="1373"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="76"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1408"/>
            <end position="1435"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1512"/>
            <end position="1573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1231"/>
            <end position="1284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1285"/>
            <end position="1303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1349"/>
            <end position="1358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1359"/>
            <end position="1372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="CRG97562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2459" mass="288770" checksum="BA1F87432CD3BC57" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYD3</accession>
    <name>A0A1J1GYD3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00506900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530297.1">
        <property type="nucleotide sequence ID" value="XM_028673890.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYD3"/>
    <dbReference type="GeneID" id="39733602"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00506900"/>
    <dbReference type="OrthoDB" id="372632at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="36"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="92"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="92"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG97496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="142" mass="16421" checksum="B4EEE21CE1DC6613" modified="2017-02-15" version="1">MICSQTCAANNTYIPSKMETFITKAPHEVTLTDSNSRLFIKNIKNGVTLEQFRHSLEKYGTVEVYLYEPGTNNNGWAWVGFENEEAALKVVEESEKPNDEEINEKEGSVHSRDDEKQDSNSFYEENEENQQNEEEEEEENDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYI7</accession>
    <name>A0A1J1GYI7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00329650</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000059">
        <property type="protein sequence ID" value="CRG96083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028528888.1">
        <property type="nucleotide sequence ID" value="XM_028672325.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYI7"/>
    <dbReference type="GeneID" id="39731826"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00329650"/>
    <dbReference type="OrthoDB" id="10641324at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG96083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="221" mass="24713" checksum="C115DDD704FE0820" modified="2017-02-15" version="1">MKSNIIFNIINMPGYGDYVAKGYMTTYIQNSKICNKKQKTNISLFSKFFLFALLIMVLEGFSSYTYKFENSKEILGGIVDLINKRNLSESSNEGITDQLKLNLLRIGDDVNREGNNPEQEPSLNESDSETDEGNDESLESLKKNEGNESNKISSGLKGKSNNMLQRSLMAAPFLFTMAMLTLNNSRTPHIPVKALAIYLGYVGALSFIDPFNTSDDDKKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="26" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYT0</accession>
    <name>A0A1J1GYT0_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="5">4-nitrophenylphosphatase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00519700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="4">Divalent metal ions. Mg(2+) is the most effective.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530422.1">
        <property type="nucleotide sequence ID" value="XM_028674028.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYT0"/>
    <dbReference type="GeneID" id="39733730"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00519700"/>
    <dbReference type="OMA" id="PPMHRET"/>
    <dbReference type="OrthoDB" id="413953at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006349">
        <property type="entry name" value="PGP_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01460">
        <property type="entry name" value="HAD-SF-IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01452">
        <property type="entry name" value="PGP_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19288">
        <property type="entry name" value="4-NITROPHENYLPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19288:SF46">
        <property type="entry name" value="HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13242">
        <property type="entry name" value="Hydrolase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000915">
        <property type="entry name" value="PGP-type_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01139">
        <property type="entry name" value="C2.A:_Pyridoxal_Phosphate_Phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00039">
        <property type="entry name" value="phosphoglycolate_phosphatase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000915-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000915-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000915-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="322" mass="37184" checksum="8D2F07EB0D7826DC" modified="2017-02-15" version="1">MSLIYSCRNNEDDLIKIEKKYEKFMKEWNIKNLVNAKDFLKNIQVFFFDCDGVLWHGDVLMDKAIEVVENLLKEEKKVYFITNNSTKSREKFLEKFHKLGFSFVKKENILCTAYAISKYFHDKEEYTSKKKKIYVIGEKGICDELDSYDLEWVGGFHDNDKKVIIKDDLEVKVDENIGAVVVGMDFNINYYKIQYAQLCINELDAEFIASNKDSTGNFTSKQKWAGTGSIVSCIEAVALKKPKILGKPNLFMIEDILKDLKVDKSKVVMIGDRLDTDINFAKNCKIKSILVSTGVTNSNIYLNHNHLNVEPDYFMKSISELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GYV9</accession>
    <name>A0A1J1GYV9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00534000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530563.1">
        <property type="nucleotide sequence ID" value="XM_028674184.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GYV9"/>
    <dbReference type="GeneID" id="39733873"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00534000"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="54" mass="6442" checksum="CCC8A86F8AEF2385" modified="2017-02-15" version="1">MNDDLEALVRKPSTEKDTDNCLNVRLYLIQILFIFIVCFVIFVFFFILFFLGVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="21" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZ24</accession>
    <name>A0A1J1GZ24_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein kinase, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">PGAL8A_00024800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530613.1">
        <property type="nucleotide sequence ID" value="XM_028674240.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZ24"/>
    <dbReference type="GeneID" id="39728771"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00024800"/>
    <dbReference type="OMA" id="KTNTIIC"/>
    <dbReference type="OrthoDB" id="447103at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051177">
        <property type="entry name" value="CIK-Related_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12984:SF3">
        <property type="entry name" value="N-TERMINAL KINASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12984">
        <property type="entry name" value="SCY1-RELATED S/T PROTEIN KINASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="HEAT" evidence="1">
        <location>
            <begin position="546"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CRG97813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="796" mass="93546" checksum="5114A944C27566D3" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZH3</accession>
    <name>A0A1J1GZH3_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SF-assemblin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00043700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530803.1">
        <property type="nucleotide sequence ID" value="XM_028674452.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZH3"/>
    <dbReference type="GeneID" id="39728962"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00043700"/>
    <dbReference type="OMA" id="EFKNEHK"/>
    <dbReference type="OrthoDB" id="298686at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038835">
        <property type="entry name" value="Giardin_beta-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37027:SF2">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_148, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37027">
        <property type="entry name" value="KDE4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="40"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="202"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="7"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG98006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="261" mass="31484" checksum="B7EFCAED7B734269" modified="2017-02-15" version="1">MDLNKSGIHSKQFSLSQNKHNNERLQRLEKRLSGLHFGIELQKNEKIEKLNEKVNVLEEKLIEMHENSNRTFEKLNEKLNDIRNDVNNYKSELEEFKNEHKKKLEILEKKADEFISKEKEEWNKLKTKLIKDFQNKTSLLKEEIIEEYGIFEEKEDSLRKYYDCELNNLKSLVQNEINERIKTERVILRDVDEKINEIMKIIKNEKVNRENYSENLVSLIEQYFSRIKKEIDKERLEREDTEETLVHLMEEALDKIGIPFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZI5</accession>
    <name>A0A1J1GZI5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fam-g protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">PGAL8A_00041300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG97984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530781.1">
        <property type="nucleotide sequence ID" value="XM_028674428.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1GZI5"/>
    <dbReference type="GeneID" id="39728938"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00041300"/>
    <dbReference type="OrthoDB" id="6475849at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CRG97984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="182" mass="22418" checksum="7F47EB5060544B1A" modified="2017-02-15" version="1">MRMLILYLKITTFLLLIWMYQCFYNCDFYKTLIDKNILQTKNELKYERVLTEGDISGKKQTYAKECIEESPLDNKKNKWENPDLYKDPYNYWYKVIIPKLWEQFDKETSEMSPNSKNREWNVEWHKLSTEKIKDLYLVTLRRYIPYEEKKKIIDSVMKELDSRFEIFLCECKIRKGKKKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="27" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZS9</accession>
    <name>A0A1J1GZS9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Pre-mRNA-processing-splicing factor 8, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">PRPF8</name>
        <name evidence="10" type="ORF">PGAL8A_00056100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000143">
        <property type="protein sequence ID" value="CRG98126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530923.1">
        <property type="nucleotide sequence ID" value="XM_028674585.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39729086"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00056100"/>
    <dbReference type="OMA" id="ANKWNTS"/>
    <dbReference type="OrthoDB" id="1931567at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
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    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097157">
        <property type="term" value="F:pre-mRNA intronic binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030619">
        <property type="term" value="F:U1 snRNA binding"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030620">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0030623">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017070">
        <property type="term" value="F:U6 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000244">
        <property type="term" value="P:spliceosomal tri-snRNP complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08056">
        <property type="entry name" value="MPN_PRP8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13838">
        <property type="entry name" value="RNase_H_like_Prp8_IV"/>
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    </dbReference>
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    <dbReference type="FunFam" id="3.30.420.230:FF:000001">
        <property type="entry name" value="Pre-mRNA-processing-splicing factor 8"/>
        <property type="match status" value="1"/>
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    <dbReference type="FunFam" id="3.90.1570.40:FF:000001">
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1570.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
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    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.40">
        <property type="entry name" value="Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PRO8NT"/>
    </dbReference>
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        <property type="entry name" value="PROCN"/>
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    <dbReference type="InterPro" id="IPR012984">
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    </dbReference>
    <dbReference type="InterPro" id="IPR027652">
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    <dbReference type="InterPro" id="IPR021983">
        <property type="entry name" value="PRP8_domainIV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043173">
        <property type="entry name" value="Prp8_domainIV_fingers"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043172">
        <property type="entry name" value="Prp8_domainIV_palm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019581">
        <property type="entry name" value="Prp8_U5-snRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042516">
        <property type="entry name" value="Prp8_U5-snRNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019580">
        <property type="entry name" value="Prp8_U6-snRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019582">
        <property type="entry name" value="RRM_spliceosomal_PrP8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11140">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR PRP8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11140:SF0">
        <property type="entry name" value="PRE-MRNA-PROCESSING-SPLICING FACTOR 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08082">
        <property type="entry name" value="PRO8NT"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF08083">
        <property type="entry name" value="PROCN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08084">
        <property type="entry name" value="PROCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12134">
        <property type="entry name" value="PRP8_domainIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10598">
        <property type="entry name" value="RRM_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10597">
        <property type="entry name" value="U5_2-snRNA_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10596">
        <property type="entry name" value="U6-snRNA_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRO8NT" evidence="3">
        <location>
            <begin position="564"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="domain" description="PROCN" evidence="4">
        <location>
            <begin position="1119"/>
            <end position="1526"/>
        </location>
    </feature>
    <feature type="domain" description="RNA recognition motif spliceosomal PrP8" evidence="8">
        <location>
            <begin position="1711"/>
            <end position="1801"/>
        </location>
    </feature>
    <feature type="domain" description="Pre-mRNA-processing-splicing factor 8 U5-snRNA-binding" evidence="7">
        <location>
            <begin position="2007"/>
            <end position="2143"/>
        </location>
    </feature>
    <feature type="domain" description="Pre-mRNA-processing-splicing factor 8 U6-snRNA-binding" evidence="6">
        <location>
            <begin position="2213"/>
            <end position="2369"/>
        </location>
    </feature>
    <feature type="domain" description="PRP8" evidence="9">
        <location>
            <begin position="2547"/>
            <end position="2776"/>
        </location>
    </feature>
    <feature type="domain" description="PROCT" evidence="5">
        <location>
            <begin position="3046"/>
            <end position="3166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="910"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1073"/>
            <end position="1092"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1947"/>
            <end position="1966"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="480"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="28"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="958"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="969"/>
            <end position="981"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1005"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1075"/>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1947"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG98126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="3170" mass="371787" checksum="F91C1E4280726A3F" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1GZV8</accession>
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        <recommendedName>
            <fullName evidence="4">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">PGAL8A_00025900</name>
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    <organism evidence="5 6">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
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            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
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            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="XM_028674252.1"/>
    </dbReference>
    <dbReference type="GeneID" id="39728782"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00025900"/>
    <dbReference type="OMA" id="LNCHHED"/>
    <dbReference type="OrthoDB" id="348671at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="Multihaem_cyt_sf"/>
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    </dbReference>
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        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
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    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
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        </location>
    </feature>
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            <end position="265"/>
        </location>
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            <end position="22"/>
        </location>
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            <end position="485"/>
        </location>
    </feature>
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            <end position="633"/>
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            <end position="1086"/>
        </location>
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            <end position="1208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
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            <begin position="1227"/>
            <end position="1258"/>
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            <end position="1448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
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            <end position="1814"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1845"/>
            <end position="1865"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
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        <location>
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        <location>
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            <end position="471"/>
        </location>
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        <location>
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        </location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
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        <location>
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        <location>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="CRG97824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="2304" mass="276534" checksum="D5C6D97E4DEAA62D" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="25" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H082</accession>
    <name>A0A1J1H082_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Triose phosphate transporter, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">TPT</name>
        <name evidence="7" type="ORF">PGAL8A_00029400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530658.1">
        <property type="nucleotide sequence ID" value="XM_028674290.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H082"/>
    <dbReference type="GeneID" id="39728817"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00029400"/>
    <dbReference type="OMA" id="FWYTVSS"/>
    <dbReference type="OrthoDB" id="6418713at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="166"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="323"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="6">
        <location>
            <begin position="44"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="344" mass="39350" checksum="A023AEC3188A7731" modified="2017-02-15" version="1">MMKDNEKNEYGTFPITINDAYSDKLKDKKYKGKDIYSTFYDKVKLIFLLITWYALNVLYNVDNKRALNMIKLPWLISCIQLFVGWIFIFIYWISGYKKVPKIYSYDLFLKNILIQSVCHILVHFGAVMSMSQTSVSFTHVVKACEPVFTAILSILLLKQYMKLNKYISLLVIVSGVVCASVKELHFTWISFWCATISNFGSSMRSIYAKKMMTQKSSIGENLNASNIYSLITIFSALISLPLVLIFEGRSAYSFLTNYQSTQSIHSFRDIVVKIFLSGMWYYLNNEVAFMCLEKINQITHAVANSVKRVVIIVSSIIIFKTQITLLGAVGSAVAIFGTFLYSIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H084</accession>
    <name>A0A1J1H084_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Elongation factor 1-alpha, putative</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">PGAL8A_00040400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000125">
        <property type="protein sequence ID" value="CRG97969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530768.1">
        <property type="nucleotide sequence ID" value="XM_028674412.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H084"/>
    <dbReference type="GeneID" id="39728928"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00040400"/>
    <dbReference type="OMA" id="KEAAEXM"/>
    <dbReference type="OrthoDB" id="407705at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03705">
        <property type="entry name" value="EF1_alpha_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000005">
        <property type="entry name" value="Elongation factor 1-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054696">
        <property type="entry name" value="GTP-eEF1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44830">
        <property type="entry name" value="ELONGATION FACTOR 1 ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44830:SF1">
        <property type="entry name" value="TR-TYPE G DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22594">
        <property type="entry name" value="GTP-eEF1A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GTP-eEF1A C-terminal" evidence="6">
        <location>
            <begin position="64"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF22594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="CRG97969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="181" mass="19911" checksum="798385FA68AE4FEF" modified="2017-02-15" version="1">MVLNFAPSAVVSECKSVEMHKEVLEEARPGDNIGFNVKNVSVKEIKRGYVASDTKNEPAKGCAKFTAQVIILNHPGEIKNGYTPVLDCHTSHISCKFVNIDSKIDKRSGKVVEENPKAIKSGDSALVSLEPKKPMVVETFTEYPPLGRFAIRDMRQTIAVGIIKSVEKKEPGAVSSNKFFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="24" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H0T7</accession>
    <name>A0A1J1H0T7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Tryptophan--tRNA ligase, putative</fullName>
            <ecNumber evidence="8">6.1.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">PGAL8A_00472700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.2" evidence="8"/>
    <dbReference type="EMBL" id="CVMV01000083">
        <property type="protein sequence ID" value="CRG97146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028529949.1">
        <property type="nucleotide sequence ID" value="XM_028673503.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H0T7"/>
    <dbReference type="GeneID" id="39733260"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00472700"/>
    <dbReference type="OMA" id="KPSGSIH"/>
    <dbReference type="OrthoDB" id="15808at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004830">
        <property type="term" value="F:tryptophan-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006436">
        <property type="term" value="P:tryptophanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.240.10">
        <property type="entry name" value="Tyrosyl-Transfer RNA Synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050203">
        <property type="entry name" value="Trp-tRNA_synthetase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43766">
        <property type="entry name" value="TRYPTOPHAN--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43766:SF1">
        <property type="entry name" value="TRYPTOPHAN--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 6 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5009618952" evidence="7">
        <location>
            <begin position="21"/>
            <end position="579"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="CRG97146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="579" mass="69165" checksum="D6C25B533231D0A0" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2G7</accession>
    <name>A0A1J1H2G7_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">PGAL8A_00526700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530492.1">
        <property type="nucleotide sequence ID" value="XM_028674106.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2G7"/>
    <dbReference type="GeneID" id="39733800"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00526700"/>
    <dbReference type="OrthoDB" id="448832at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="134"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="652"/>
            <end position="679"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="CRG97691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="874" mass="104594" checksum="D54E346F620246FE" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="38" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H2L6</accession>
    <name>A0A1J1H2L6_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glycerol-3-phosphate dehydrogenase [NAD(+)]</fullName>
            <ecNumber evidence="9">1.1.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">PGAL8A_00530800</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">8A</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4 9">
            <text>sn-glycerol 3-phosphate + NAD(+) = dihydroxyacetone phosphate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11092"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.8" evidence="9"/>
    <dbReference type="EMBL" id="CVMV01000110">
        <property type="protein sequence ID" value="CRG97731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530532.1">
        <property type="nucleotide sequence ID" value="XM_028674150.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H2L6"/>
    <dbReference type="GeneID" id="39733841"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00530800"/>
    <dbReference type="OMA" id="ENEVKMW"/>
    <dbReference type="OrthoDB" id="10263760at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141152">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046168">
        <property type="term" value="P:glycerol-3-phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000004">
        <property type="entry name" value="Glycerol-3-phosphate dehydrogenase [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006168">
        <property type="entry name" value="G3P_DH_NAD-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006109">
        <property type="entry name" value="G3P_DH_NAD-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017751">
        <property type="entry name" value="G3P_DH_NAD-dep_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011128">
        <property type="entry name" value="G3P_DH_NAD-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03376">
        <property type="entry name" value="glycerol3P_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11728">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11728:SF8">
        <property type="entry name" value="GLYCEROL-3-PHOSPHATE DEHYDROGENASE [NAD(+)]-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07479">
        <property type="entry name" value="NAD_Gly3P_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01210">
        <property type="entry name" value="NAD_Gly3P_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000114">
        <property type="entry name" value="Glycerol-3-P_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00077">
        <property type="entry name" value="GPDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 8" id="KW-0520">NAD</keyword>
    <keyword evidence="2 8 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal" evidence="10">
        <location>
            <begin position="15"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal" evidence="11">
        <location>
            <begin position="208"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="282"/>
            <end position="283"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="CRG97731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="367" mass="41465" checksum="BA42E61790DADB37" modified="2017-02-15" version="1">MYKNLFDKLKDGPLKISILGSGNWASAISKVVGTNAQNNYLFENEVKIWVRDEVFDGEKMEDIINQKHENLKYLKGVALPHNIVAYSDIAEVVNHADLLIFIIPCQYLENVLLMIHQNKSIKIAKHVKAISLTKGFIIKDNKINLCSKVISNFLNIPCCALSGANIAKDVGMEEFSEATIGGDDRDVLLIWQRVFDLPYFKINCVNETVGVEICGALKNIITLAAGFCDGLNASPNSKSAIIRIGINETKLFAKIFFNNFNESIFFESCGFADIITSFLGGRNAKCSAEFIKCKQKRSWEELENEILKGQKLQGTLTLKYIYQMIREKDLTKDFPLFTILHKISFEKEEPLNLLKTFMDNRMAPLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="35" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3F1</accession>
    <name>A0A1J1H3F1_PLAGA</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">asparagine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">AsnRS</name>
        <name evidence="10" type="ORF">PGAL8A_00030700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">8A</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.22" evidence="2"/>
    <dbReference type="EMBL" id="CVMV01000117">
        <property type="protein sequence ID" value="CRG97872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530671.1">
        <property type="nucleotide sequence ID" value="XM_028674304.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3F1"/>
    <dbReference type="GeneID" id="39728830"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00030700"/>
    <dbReference type="OMA" id="YLRNFPH"/>
    <dbReference type="OrthoDB" id="1931232at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004816">
        <property type="term" value="F:asparagine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006421">
        <property type="term" value="P:asparaginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04318">
        <property type="entry name" value="EcAsnRS_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004522">
        <property type="entry name" value="Asn-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00457">
        <property type="entry name" value="asnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594:SF34">
        <property type="entry name" value="ASPARAGINE--TRNA LIGASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594">
        <property type="entry name" value="ASPARTYL/LYSYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012746336" description="asparagine--tRNA ligase" evidence="8">
        <location>
            <begin position="25"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="9">
        <location>
            <begin position="403"/>
            <end position="632"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="CRG97872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="640" mass="75797" checksum="C1036CC175E49910" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2017-02-15" modified="2026-01-28" version="30" xmlns="https://uniprot.org/uniprot">
    <accession>A0A1J1H3U9</accession>
    <name>A0A1J1H3U9_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA helicase, putative</fullName>
            <ecNumber evidence="4">3.6.4.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">PGAL8A_00045700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">8A</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="4"/>
    <dbReference type="EMBL" id="CVMV01000132">
        <property type="protein sequence ID" value="CRG98026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="XP_028530823.1">
        <property type="nucleotide sequence ID" value="XM_028674474.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A1J1H3U9"/>
    <dbReference type="GeneID" id="39728982"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_00045700"/>
    <dbReference type="OMA" id="TKTFCIS"/>
    <dbReference type="OrthoDB" id="382810at2759"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="714"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="505"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="69"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="CRG98026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000220797"/>
        </source>
    </evidence>
    <sequence length="1025" mass="122910" checksum="1527C225E6FAF2F9" modified="2017-02-15" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2012-05-16" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>H7CDY5</accession>
    <name>H7CDY5_PLAGA</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Open reading frame 78</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ORF78</name>
        <name evidence="3" type="ORF">PGAL8A_API02900</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Plasmodium gallinaceum</name>
        <dbReference type="NCBI Taxonomy" id="5849"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Sar</taxon>
            <taxon>Alveolata</taxon>
            <taxon>Apicomplexa</taxon>
            <taxon>Aconoidasida</taxon>
            <taxon>Haemosporida</taxon>
            <taxon>Plasmodiidae</taxon>
            <taxon>Plasmodium</taxon>
            <taxon>Plasmodium (Haemamoeba)</taxon>
        </lineage>
    </organism>
    <geneLocation type="apicoplast" evidence="2"/>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2012" name="Mol. Biol. Evol." volume="29" first="2095" last="2099">
            <title>The Plasmodium Apicoplast Genome: Conserved Structure and Close Relationship of P. ovale to Rodent Malaria Parasites.</title>
            <authorList>
                <person name="Arisue N."/>
                <person name="Hashimoto T."/>
                <person name="Mitsui H."/>
                <person name="Palacpac N.M.Q."/>
                <person name="Kaneko A."/>
                <person name="Kawai S."/>
                <person name="Hasegawa M."/>
                <person name="Tanabe K."/>
                <person name="Horii T."/>
            </authorList>
            <dbReference type="PubMed" id="22396524"/>
            <dbReference type="DOI" id="10.1093/molbev/mss082"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">A8</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="2">
        <citation type="submission" date="2015-04" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <consortium name="Pathogen Informatics"/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">8A</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AB649424">
        <property type="protein sequence ID" value="BAL70755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LN835293">
        <property type="protein sequence ID" value="CRG98244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_009325471.1">
        <property type="nucleotide sequence ID" value="NC_031963.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="H7CDY5"/>
    <dbReference type="GeneID" id="30315816"/>
    <dbReference type="VEuPathDB" id="PlasmoDB:PGAL8A_API02900"/>
    <dbReference type="OMA" id="CQKSDLN"/>
    <dbReference type="Proteomes" id="UP000220797">
        <property type="component" value="Apicoplast API"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0933">Apicoplast</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0934">Plastid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAL70755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbRefer